locus-tag	class	description
H9S87_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9S87_00010	COG0592	DNA-directed DNA polymerase activity
H9S87_00015	COG2501	S4 domain
H9S87_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9S87_00030	COG0187	DNA topoisomerase II activity
H9S87_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9S87_00070	COG0516	GMP reductase activity
H9S87_00070	COG0517	IMP dehydrogenase activity
H9S87_00075	COG1686	Belongs to the peptidase S11 family
H9S87_00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9S87_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
H9S87_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
H9S87_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9S87_00100	COG0840	transmembrane signaling receptor activity
H9S87_00110	COG1428	Deoxynucleoside kinase
H9S87_00115	COG1428	Deoxynucleoside kinase
H9S87_00120	COG3858	chitin binding
H9S87_00120	COG1388	LysM domain
H9S87_00125	COG1335	isochorismatase
H9S87_00130	COG0590	tRNA wobble adenosine to inosine editing
H9S87_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9S87_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9S87_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9S87_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H9S87_00200	COG3853	Toxic anion resistance protein (TelA)
H9S87_00205	COG1982	Orn Lys Arg decarboxylase major
H9S87_00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9S87_00215	COG3870	Protein conserved in bacteria
H9S87_00220	COG1728	Protein conserved in bacteria
H9S87_00225	COG0470	DNA polymerase III
H9S87_00230	COG1774	PSP1 C-terminal conserved region
H9S87_00235	COG4467	Involved in initiation control of chromosome replication
H9S87_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9S87_00245	COG2827	Endonuclease containing a URI domain
H9S87_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9S87_00255	COG2002	toxin-antitoxin pair type II binding
H9S87_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9S87_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9S87_00265	COG0084	hydrolase, TatD family'
H9S87_00270	COG3584	3D domain protein
H9S87_00270	COG3583	domain protein
H9S87_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H9S87_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9S87_00290	COG4466	Protein conserved in bacteria
H9S87_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9S87_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9S87_00310	COG0251	oxidation-reduction process
H9S87_00315	COG2088	sporulation resulting in formation of a cellular spore
H9S87_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9S87_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H9S87_00335	COG0193	aminoacyl-tRNA hydrolase activity
H9S87_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9S87_00350	COG2002	toxin-antitoxin pair type II binding
H9S87_00355	COG2244	polysaccharide biosynthetic process
H9S87_00360	COG3956	TIGRFAM MazG family protein
H9S87_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9S87_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H9S87_00385	COG1098	S1 RNA binding domain
H9S87_00400	COG2208	phosphoserine phosphatase activity
H9S87_00405	COG2304	oxidoreductase activity
H9S87_00410	COG0515	serine threonine protein kinase
H9S87_00415	COG0037	tRNA processing
H9S87_00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H9S87_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9S87_00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9S87_00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9S87_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9S87_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9S87_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9S87_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
H9S87_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9S87_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9S87_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9S87_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9S87_00480	COG1396	sequence-specific DNA binding
H9S87_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9S87_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9S87_00570	COG4463	regulation of RNA biosynthetic process
H9S87_00575	COG3880	PFAM UvrB UvrC protein
H9S87_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
H9S87_00585	COG0542	response to heat
H9S87_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9S87_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H9S87_00600	COG4956	integral membrane protein (PIN domain superfamily)
H9S87_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9S87_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9S87_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9S87_00620	COG1045	serine acetyltransferase
H9S87_00625	COG0215	cysteine-tRNA ligase activity
H9S87_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H9S87_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9S87_00640	COG3688	RNA-binding protein containing a PIN domain
H9S87_00645	COG1595	DNA-templated transcription, initiation
H9S87_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9S87_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9S87_00660	COG0250	Participates in transcription elongation, termination and antitermination
H9S87_00670	COG0081	regulation of translation
H9S87_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9S87_00680	COG0222	ribosome binding
H9S87_00685	COG2813	Specifically methylates the guanine in position
H9S87_00690	COG0085	RNA polymerase activity
H9S87_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9S87_00700	COG1358	cellular component organization or biogenesis
H9S87_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9S87_00710	COG0049	tRNA binding
H9S87_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9S87_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9S87_00725	COG0596	Alpha beta hydrolase
H9S87_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9S87_00740	COG0088	Forms part of the polypeptide exit tunnel
H9S87_00745	COG0089	rRNA binding
H9S87_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9S87_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9S87_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9S87_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9S87_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
H9S87_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9S87_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9S87_00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9S87_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9S87_00800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9S87_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9S87_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9S87_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9S87_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9S87_00825	COG1841	ribosomal large subunit assembly
H9S87_00830	COG0200	Binds to the 23S rRNA
H9S87_00835	COG0201	protein transport
H9S87_00840	COG0563	adenylate kinase activity
H9S87_00845	COG0024	Methionine aminopeptidase
H9S87_00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9S87_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9S87_00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9S87_00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9S87_00870	COG0202	RNA polymerase activity
H9S87_00875	COG0203	ribosomal protein L17
H9S87_00880	COG1122	ATPase activity
H9S87_00885	COG1122	ATPase activity
H9S87_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H9S87_00895	COG0101	tRNA pseudouridine synthase activity
H9S87_00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9S87_00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9S87_00910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9S87_00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9S87_00945	COG0489	protein tyrosine kinase activity
H9S87_00955	COG2194	sulfuric ester hydrolase activity
H9S87_00960	COG0726	polysaccharide deacetylase
H9S87_00990	COG0659	secondary active sulfate transmembrane transporter activity
H9S87_00995	COG0385	Bile acid
H9S87_01000	COG3876	Protein conserved in bacteria
H9S87_01005	COG1472	Belongs to the glycosyl hydrolase 3 family
H9S87_01010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9S87_01015	COG1263	PTS System
H9S87_01015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_01020	COG1737	Transcriptional regulator
H9S87_01025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9S87_01060	COG1595	DNA-templated transcription, initiation
H9S87_01065	COG5662	AntiSigma factor
H9S87_01070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H9S87_01075	COG4856	YbbR-like protein
H9S87_01080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9S87_01085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9S87_01105	COG1131	(ABC) transporter
H9S87_01120	COG1131	(ABC) transporter
H9S87_01130	COG1413	lyase activity
H9S87_01135	COG2311	Membrane
H9S87_01155	COG1309	transcriptional regulator
H9S87_01170	COG1113	amino acid transport
H9S87_01175	COG0584	glycerophosphoryl diester phosphodiesterase
H9S87_01180	COG2271	Major facilitator Superfamily
H9S87_01190	COG1331	Highly conserved protein containing a thioredoxin domain
H9S87_01205	COG1937	Protein conserved in bacteria
H9S87_01210	COG2210	Belongs to the sulfur carrier protein TusA family
H9S87_01215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9S87_01220	COG0425	Belongs to the sulfur carrier protein TusA family
H9S87_01220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9S87_01225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9S87_01225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9S87_01230	COG0425	Belongs to the sulfur carrier protein TusA family
H9S87_01235	COG0730	response to heat
H9S87_01245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9S87_01250	COG2814	Major facilitator Superfamily
H9S87_01255	COG1846	Transcriptional regulator
H9S87_01265	COG1683	Conserved Protein
H9S87_01275	COG0656	L-ascorbic acid biosynthetic process
H9S87_01280	COG0371	Dehydrogenase
H9S87_01285	COG1054	Belongs to the UPF0176 family
H9S87_01290	COG0531	amino acid
H9S87_01300	COG3711	transcriptional antiterminator
H9S87_01305	COG2190	(PTS) system
H9S87_01305	COG1263	PTS System
H9S87_01305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_01310	COG2723	6-phospho-beta-galactosidase activity
H9S87_01320	COG3711	transcriptional antiterminator
H9S87_01320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_01325	COG1940	carbohydrate kinase activity
H9S87_01330	COG0383	alpha-mannosidase activity
H9S87_01335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_01340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_01350	COG1404	Belongs to the peptidase S8 family
H9S87_01365	COG0833	amino acid
H9S87_01370	COG2040	homocysteine
H9S87_01375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9S87_01380	COG1695	Transcriptional regulator
H9S87_01395	COG2814	Major facilitator Superfamily
H9S87_01400	COG0456	acetyltransferase
H9S87_01410	COG1404	Belongs to the peptidase S8 family
H9S87_01420	COG1309	transcriptional regulator
H9S87_01425	COG1917	Cupin 2, conserved barrel domain protein
H9S87_01430	COG1063	alcohol dehydrogenase
H9S87_01435	COG1846	Transcriptional regulator
H9S87_01440	COG0318	PFAM AMP-dependent synthetase and ligase
H9S87_01445	COG0531	amino acid
H9S87_01465	COG0596	Alpha beta hydrolase
H9S87_01470	COG1115	amino acid carrier protein
H9S87_01475	COG2066	Belongs to the glutaminase family
H9S87_01480	COG4191	Histidine kinase
H9S87_01485	COG0784	Response regulator, receiver
H9S87_01490	COG3012	SEC-C Motif Domain Protein
H9S87_01490	COG1405	negative regulation of cell septum assembly
H9S87_01500	COG0667	Aldo Keto reductase
H9S87_01505	COG3290	protein histidine kinase activity
H9S87_01510	COG3279	Response regulator of the LytR AlgR family
H9S87_01515	COG4555	ABC transporter
H9S87_01520	COG1668	transmembrane transport
H9S87_01535	COG3773	Cell wall hydrolase
H9S87_01540	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_01550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9S87_01555	COG2310	stress, protein
H9S87_01560	COG2310	stress, protein
H9S87_01565	COG2310	stress, protein
H9S87_01570	COG0861	Integral membrane protein TerC family
H9S87_01600	COG3853	Toxic anion resistance protein (TelA)
H9S87_01605	COG4175	Glycine betaine
H9S87_01605	COG0517	IMP dehydrogenase activity
H9S87_01610	COG4176	ABC-type proline glycine betaine transport system permease component
H9S87_01615	COG2113	Glycine betaine
H9S87_01630	COG1473	amidohydrolase
H9S87_01635	COG1288	antiporter activity
H9S87_01640	COG0039	L-malate dehydrogenase activity
H9S87_01645	COG1620	l-lactate permease
H9S87_01650	COG1609	Transcriptional regulator
H9S87_01655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9S87_01660	COG0561	phosphatase activity
H9S87_01665	COG0673	inositol 2-dehydrogenase activity
H9S87_01670	COG0738	Major facilitator superfamily
H9S87_01675	COG1280	lysine exporter protein (LysE YggA)
H9S87_01685	COG3403	YqcI/YcgG family
H9S87_01690	COG1113	amino acid transport
H9S87_01695	COG3665	Urea carboxylase-associated protein
H9S87_01700	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9S87_01705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9S87_01715	COG0477	Major facilitator Superfamily
H9S87_01720	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9S87_01725	COG2226	methyltransferase
H9S87_01730	COG0583	DNA-binding transcription factor activity
H9S87_01735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9S87_01740	COG3458	cephalosporin-C deacetylase activity
H9S87_01750	COG3541	Predicted nucleotidyltransferase
H9S87_01755	COG0506	proline dehydrogenase activity
H9S87_01760	COG1012	belongs to the aldehyde dehydrogenase family
H9S87_01765	COG2508	Transcriptional regulator
H9S87_01770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9S87_01775	COG0765	amino acid transport
H9S87_01780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_01790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H9S87_01795	COG1522	sequence-specific DNA binding
H9S87_01800	COG2746	aminoglycoside 3-N-acetyltransferase activity
H9S87_01815	COG3209	COG3209 Rhs family protein
H9S87_01835	COG3842	ATPase activity
H9S87_01840	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9S87_01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9S87_01855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9S87_01860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9S87_01875	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H9S87_01890	COG4555	ABC transporter
H9S87_01905	COG0697	spore germination
H9S87_01910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9S87_01920	COG2364	Membrane
H9S87_01925	COG1126	abc transporter atp-binding protein
H9S87_01930	COG0765	amino acid transport
H9S87_01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_01940	COG0833	amino acid
H9S87_01945	COG3104	oligopeptide transport
H9S87_01950	COG5434	Belongs to the glycosyl hydrolase 28 family
H9S87_01955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9S87_01960	COG0456	acetyltransferase
H9S87_01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_01970	COG0765	amino acid transport
H9S87_01975	COG1126	abc transporter atp-binding protein
H9S87_01980	COG1473	amidohydrolase
H9S87_01985	COG2079	MmgE PrpD family protein
H9S87_01990	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_01995	COG0527	aspartate kinase activity
H9S87_02000	COG2814	Major facilitator Superfamily
H9S87_02005	COG1309	transcriptional regulator
H9S87_02010	COG0640	Transcriptional regulator
H9S87_02015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9S87_02020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9S87_02025	COG0531	amino acid
H9S87_02030	COG1012	belongs to the aldehyde dehydrogenase family
H9S87_02035	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9S87_02040	COG4549	nuclear export factor GLE1
H9S87_02045	COG1276	copper resistance
H9S87_02045	COG2372	response to copper ion
H9S87_02050	COG2213	PTS system mannitol-specific
H9S87_02055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_02060	COG0246	Mannitol dehydrogenase
H9S87_02085	COG0346	lactoylglutathione lyase activity
H9S87_02095	COG0561	phosphatase activity
H9S87_02100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H9S87_02105	COG1914	H( )-stimulated, divalent metal cation uptake system
H9S87_02110	COG4336	lyase activity
H9S87_02115	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H9S87_02120	COG1984	allophanate hydrolase subunit 2
H9S87_02125	COG1414	Transcriptional regulator
H9S87_02130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9S87_02135	COG2755	lipolytic protein G-D-S-L family
H9S87_02145	COG3711	transcriptional antiterminator
H9S87_02150	COG2226	methyltransferase
H9S87_02155	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_02160	COG3871	stress protein (general stress protein 26)
H9S87_02175	COG2814	Major facilitator Superfamily
H9S87_02180	COG1802	Transcriptional regulator
H9S87_02185	COG2207	Transcriptional regulator
H9S87_02185	COG1917	Cupin 2, conserved barrel domain protein
H9S87_02190	COG0697	spore germination
H9S87_02195	COG0473	3-isopropylmalate dehydrogenase activity
H9S87_02200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9S87_02200	COG0551	DNA topoisomerase type I activity
H9S87_02205	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H9S87_02210	COG3706	GGDEF domain
H9S87_02215	COG5298	Protein conserved in bacteria
H9S87_02220	COG1215	transferase activity, transferring glycosyl groups
H9S87_02230	COG0531	amino acid
H9S87_02235	COG0028	Belongs to the TPP enzyme family
H9S87_02240	COG5444	nuclease activity
H9S87_02265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9S87_02270	COG1914	H( )-stimulated, divalent metal cation uptake system
H9S87_02275	COG2261	transglycosylase associated protein
H9S87_02280	COG2217	Heavy metal translocating P-type atpase
H9S87_02285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9S87_02290	COG3290	protein histidine kinase activity
H9S87_02295	COG4565	transcriptional regulatory protein
H9S87_02300	COG1301	dicarboxylic acid transport
H9S87_02305	COG0628	permease
H9S87_02310	COG1301	dicarboxylic acid transport
H9S87_02315	COG1131	(ABC) transporter
H9S87_02320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H9S87_02335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_02340	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9S87_02345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9S87_02360	COG0513	Belongs to the DEAD box helicase family
H9S87_02365	COG3402	PFAM membrane-flanked domain
H9S87_02370	COG3428	Bacterial PH domain
H9S87_02375	COG0705	Rhomboid family
H9S87_02380	COG0736	holo-[acyl-carrier-protein] synthase activity
H9S87_02385	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H9S87_02390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9S87_02395	COG0864	Transcriptional regulator
H9S87_02400	COG2337	Toxic component of a toxin-antitoxin (TA) module
H9S87_02405	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_02410	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_02415	COG2172	sigma factor antagonist activity
H9S87_02420	COG2208	phosphoserine phosphatase activity
H9S87_02425	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_02430	COG2172	sigma factor antagonist activity
H9S87_02435	COG1191	sigma factor activity
H9S87_02440	COG2208	phosphoserine phosphatase activity
H9S87_02445	COG2183	response to ionizing radiation
H9S87_02455	COG3091	SprT-like family
H9S87_02460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9S87_02465	COG0022	dehydrogenase e1 component
H9S87_02470	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9S87_02475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9S87_02480	COG3284	Transcriptional regulator
H9S87_02520	COG0604	alcohol dehydrogenase
H9S87_02535	COG1278	Cold shock
H9S87_02540	COG1329	Transcriptional regulator
H9S87_02545	COG1064	alcohol dehydrogenase
H9S87_02550	COG0789	Transcriptional regulator
H9S87_02565	COG0477	Major facilitator Superfamily
H9S87_02570	COG0657	acetylesterase activity
H9S87_02590	COG0252	asparaginase activity
H9S87_02610	COG2814	Major facilitator Superfamily
H9S87_02640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9S87_02645	COG1846	Transcriptional regulator
H9S87_02650	COG0778	Nitroreductase
H9S87_02665	COG1396	sequence-specific DNA binding
H9S87_02675	COG0456	acetyltransferase
H9S87_02680	COG0583	DNA-binding transcription factor activity
H9S87_02685	COG0667	Aldo Keto reductase
H9S87_02700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H9S87_02705	COG0697	spore germination
H9S87_02715	COG1301	dicarboxylic acid transport
H9S87_02755	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H9S87_02760	COG0802	atpase or kinase
H9S87_02765	COG1214	PFAM Peptidase M22, glycoprotease
H9S87_02770	COG0456	acetyltransferase
H9S87_02775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9S87_02780	COG0488	(ABC) transporter
H9S87_02785	COG0315	cyclic pyranopterin monophosphate synthase activity
H9S87_02790	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H9S87_02795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9S87_02800	COG0805	protein transport
H9S87_02805	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
H9S87_02815	COG1266	CAAX protease self-immunity
H9S87_02820	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9S87_02825	COG0459	protein refolding
H9S87_02835	COG1846	Transcriptional regulator
H9S87_02840	COG0456	acetyltransferase
H9S87_02845	COG2808	Putative FMN-binding domain
H9S87_02865	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9S87_02870	COG0823	Involved in the tonB-independent uptake of proteins
H9S87_02885	COG2132	Multicopper oxidase
H9S87_02890	COG1113	amino acid transport
H9S87_02895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9S87_02900	COG0714	Associated with various cellular activities
H9S87_02905	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H9S87_02910	COG1305	Transglutaminase-like
H9S87_02915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9S87_02915	COG0519	Catalyzes the synthesis of GMP from XMP
H9S87_02930	COG2207	Transcriptional regulator
H9S87_02950	COG2814	Major facilitator Superfamily
H9S87_02955	COG0583	DNA-binding transcription factor activity
H9S87_02960	COG2252	PERMEase
H9S87_02965	COG3064	Membrane
H9S87_02970	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
H9S87_02980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9S87_02985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9S87_02990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9S87_02995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9S87_03000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9S87_03005	COG0047	phosphoribosylformylglycinamidine synthase activity
H9S87_03010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9S87_03015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H9S87_03020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9S87_03025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9S87_03030	COG0138	bifunctional purine biosynthesis protein purh
H9S87_03035	COG0151	Belongs to the GarS family
H9S87_03055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9S87_03060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H9S87_03065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H9S87_03070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9S87_03080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H9S87_03085	COG4496	protein, YerC YecD
H9S87_03090	COG0069	glutamate synthase activity
H9S87_03105	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H9S87_03110	COG0210	DNA helicase
H9S87_03115	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9S87_03120	COG4851	CamS sex pheromone cAM373 precursor
H9S87_03135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H9S87_03150	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9S87_03165	COG1960	acyl-CoA dehydrogenase activity
H9S87_03195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9S87_03200	COG1785	Belongs to the alkaline phosphatase family
H9S87_03205	COG1285	pathogenesis
H9S87_03210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9S87_03215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9S87_03220	COG0154	amidase activity
H9S87_03225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9S87_03230	COG1309	transcriptional regulator
H9S87_03235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9S87_03240	COG1957	nucleoside hydrolase
H9S87_03245	COG1597	lipid kinase activity
H9S87_03250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9S87_03270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9S87_03280	COG1737	Transcriptional regulator
H9S87_03285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_03285	COG1263	PTS System
H9S87_03305	COG0492	ferredoxin-NADP+ reductase activity
H9S87_03320	COG1486	melibiose metabolic process
H9S87_03330	COG2211	Major facilitator Superfamily
H9S87_03360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H9S87_03365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9S87_03370	COG1442	glycosyl transferase family 8
H9S87_03375	COG1216	Glycosyl transferase, family 2
H9S87_03380	COG1442	glycosyl transferase family 8
H9S87_03385	COG2223	nitrite transmembrane transporter activity
H9S87_03395	COG0471	metal ion transport
H9S87_03400	COG0531	amino acid
H9S87_03405	COG0457	Tetratricopeptide repeat
H9S87_03405	COG0463	Glycosyl transferase, family 2
H9S87_03410	COG0488	(ABC) transporter
H9S87_03415	COG1469	GTP cyclohydrolase I activity
H9S87_03420	COG0789	Transcriptional regulator
H9S87_03425	COG2814	Major facilitator Superfamily
H9S87_03430	COG0488	(ABC) transporter
H9S87_03435	COG0513	Belongs to the DEAD box helicase family
H9S87_03440	COG2130	NADP-dependent
H9S87_03460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9S87_03460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9S87_03465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H9S87_03475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9S87_03475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9S87_03485	COG3290	protein histidine kinase activity
H9S87_03490	COG4565	transcriptional regulatory protein
H9S87_03495	COG3181	Tripartite tricarboxylate transporter family receptor
H9S87_03500	COG2851	Citrate transporter
H9S87_03510	COG3479	Phenolic acid decarboxylase
H9S87_03515	COG1695	Transcriptional regulator
H9S87_03520	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H9S87_03525	COG1254	Belongs to the acylphosphatase family
H9S87_03530	COG2258	MOSC domain
H9S87_03540	COG0024	Methionine aminopeptidase
H9S87_03545	COG1263	PTS System
H9S87_03545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_03550	COG3739	integral membrane protein
H9S87_03565	COG1368	sulfuric ester hydrolase activity
H9S87_03570	COG0076	glutamate decarboxylase activity
H9S87_03575	COG0840	transmembrane signaling receptor activity
H9S87_03585	COG1263	PTS System
H9S87_03585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_03590	COG0366	Alpha amylase catalytic
H9S87_03595	COG2188	Transcriptional regulator
H9S87_03605	COG0737	Belongs to the 5'-nucleotidase family
H9S87_03610	COG0693	protein deglycase activity
H9S87_03615	COG4840	Belongs to the UPF0435 family
H9S87_03620	COG1115	amino acid carrier protein
H9S87_03625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9S87_03630	COG4980	gas vesicle protein
H9S87_03635	COG1295	ribonuclease BN
H9S87_03640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9S87_03645	COG0477	Major facilitator Superfamily
H9S87_03655	COG0387	Pfam Sodium calcium exchanger
H9S87_03665	COG0217	transcriptional regulatory protein
H9S87_03675	COG0668	transmembrane transport
H9S87_03680	COG0535	radical SAM domain protein
H9S87_03690	COG0726	polysaccharide deacetylase
H9S87_03700	COG0598	Magnesium transport protein CorA
H9S87_03710	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9S87_03715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9S87_03720	COG1309	transcriptional regulator
H9S87_03725	COG1090	epimerase
H9S87_03740	COG0789	Transcriptional regulator
H9S87_03745	COG2814	Major facilitator Superfamily
H9S87_03760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9S87_03800	COG2076	Multidrug Resistance protein
H9S87_03805	COG2076	Multidrug Resistance protein
H9S87_03810	COG1309	transcriptional regulator
H9S87_03820	COG4637	Psort location Cytoplasmic, score
H9S87_03825	COG2755	lipolytic protein G-D-S-L family
H9S87_03830	COG0492	ferredoxin-NADP+ reductase activity
H9S87_03835	COG1742	UPF0060 membrane protein
H9S87_03850	COG2318	DinB family
H9S87_03860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9S87_03875	COG1846	Transcriptional regulator
H9S87_03880	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H9S87_03880	COG0392	lysyltransferase activity
H9S87_03900	COG0778	Nitroreductase
H9S87_03915	COG1090	epimerase
H9S87_03920	COG2137	regulation of response to DNA damage stimulus
H9S87_03945	COG0463	Glycosyl transferase, family 2
H9S87_03950	COG4485	Bacterial membrane protein, YfhO
H9S87_03965	COG2140	Oxalate decarboxylase
H9S87_03975	COG1191	sigma factor activity
H9S87_03985	COG1988	membrane-bound metal-dependent
H9S87_03990	COG1194	a g-specific adenine glycosylase
H9S87_04000	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_04015	COG3557	Belongs to the UPF0374 family
H9S87_04020	COG1132	(ABC) transporter
H9S87_04025	COG0444	Belongs to the ABC transporter superfamily
H9S87_04030	COG4608	Belongs to the ABC transporter superfamily
H9S87_04035	COG0747	negative chemotaxis
H9S87_04040	COG0601	transmembrane transport
H9S87_04045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9S87_04050	COG4129	membrane
H9S87_04055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9S87_04060	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9S87_04065	COG0735	belongs to the Fur family
H9S87_04205	COG1368	sulfuric ester hydrolase activity
H9S87_04210	COG0681	Belongs to the peptidase S26 family
H9S87_04215	COG2873	o-acetylhomoserine
H9S87_04225	COG1131	(ABC) transporter
H9S87_04255	COG3382	B3 4 domain protein
H9S87_04260	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9S87_04270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9S87_04280	COG2766	serine protein kinase
H9S87_04285	COG2718	Belongs to the UPF0229 family
H9S87_04290	COG1566	PFAM secretion protein HlyD family protein
H9S87_04295	COG2814	Major facilitator Superfamily
H9S87_04300	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9S87_04310	COG1278	Cold shock
H9S87_04315	COG3706	GGDEF domain
H9S87_04340	COG5577	PFAM Coat F domain
H9S87_04345	COG5002	protein histidine kinase activity
H9S87_04350	COG0737	Belongs to the 5'-nucleotidase family
H9S87_04350	COG4085	toxin activity
H9S87_04350	COG1525	nuclease
H9S87_04355	COG3764	Sortase (surface protein transpeptidase)
H9S87_04360	COG0564	pseudouridine synthase activity
H9S87_04370	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9S87_04375	COG3153	acetyltransferase
H9S87_04375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9S87_04390	COG3835	regulator
H9S87_04395	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9S87_04400	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H9S87_04405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9S87_04410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9S87_04415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H9S87_04420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9S87_04425	COG4585	Histidine kinase
H9S87_04425	COG2203	Gaf domain
H9S87_04430	COG2197	response regulator
H9S87_04450	COG0753	catalase activity
H9S87_04455	COG1959	2 iron, 2 sulfur cluster binding
H9S87_04460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9S87_04460	COG1017	nitric oxide dioxygenase activity
H9S87_04465	COG2719	SpoVR family
H9S87_04470	COG2721	sulfolactate sulfo-lyase activity
H9S87_04475	COG2186	Transcriptional regulator
H9S87_04480	COG4948	Mandelate Racemase Muconate Lactonizing
H9S87_04485	COG2271	Major facilitator Superfamily
H9S87_04490	COG1012	belongs to the aldehyde dehydrogenase family
H9S87_04495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9S87_04500	COG1785	Belongs to the alkaline phosphatase family
H9S87_04505	COG0791	NLP P60 protein
H9S87_04505	COG1388	LysM domain
H9S87_04520	COG1595	DNA-templated transcription, initiation
H9S87_04525	COG0204	Acyl-transferase
H9S87_04530	COG1253	flavin adenine dinucleotide binding
H9S87_04535	COG0789	Transcriptional regulator
H9S87_04540	COG1253	flavin adenine dinucleotide binding
H9S87_04555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9S87_04560	COG0584	glycerophosphoryl diester phosphodiesterase
H9S87_04570	COG0668	transmembrane transport
H9S87_04575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9S87_04580	COG0726	polysaccharide deacetylase
H9S87_04590	COG0589	response to stress
H9S87_04595	COG1132	(ABC) transporter
H9S87_04600	COG1132	(ABC) transporter
H9S87_04605	COG0702	epimerase
H9S87_04615	COG3842	ATPase activity
H9S87_04620	COG2508	Transcriptional regulator
H9S87_04630	COG0189	ligase activity
H9S87_04635	COG0189	ligase activity
H9S87_04640	COG4399	Belongs to the UPF0754 family
H9S87_04645	COG3679	Belongs to the UPF0342 family
H9S87_04650	COG0561	phosphatase activity
H9S87_04655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9S87_04665	COG0475	glutathione-regulated potassium exporter activity
H9S87_04670	COG0490	domain, Protein
H9S87_04680	COG1024	Enoyl-CoA hydratase
H9S87_04690	COG0420	3'-5' exonuclease activity
H9S87_04695	COG4717	serine-type aminopeptidase activity
H9S87_04700	COG3481	metal-dependent phosphohydrolase, HD sub domain
H9S87_04710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9S87_04735	COG1846	Transcriptional regulator
H9S87_04740	COG4980	gas vesicle protein
H9S87_04755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H9S87_04760	COG0537	adenosine 5'-monophosphoramidase activity
H9S87_04765	COG1131	(ABC) transporter
H9S87_04770	COG4473	ABC transporter
H9S87_04785	COG1473	amidohydrolase
H9S87_04795	COG2329	Antibiotic biosynthesis monooxygenase
H9S87_04800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9S87_04805	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9S87_04810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9S87_04815	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H9S87_04820	COG1309	transcriptional regulator
H9S87_04825	COG1511	domain protein
H9S87_04830	COG1363	Peptidase, m42
H9S87_04835	COG1301	dicarboxylic acid transport
H9S87_04845	COG1234	tRNA 3'-trailer cleavage
H9S87_04850	COG0095	Lipoate-protein ligase
H9S87_04855	COG0318	PFAM AMP-dependent synthetase and ligase
H9S87_04865	COG0501	Belongs to the peptidase M48B family
H9S87_04870	COG1404	Belongs to the peptidase S8 family
H9S87_04875	COG0406	alpha-ribazole phosphatase activity
H9S87_04880	COG0840	transmembrane signaling receptor activity
H9S87_04885	COG0723	plastoquinol--plastocyanin reductase activity
H9S87_04885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9S87_04890	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_04900	COG4903	ComK protein
H9S87_04915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9S87_04920	COG2814	Major facilitator Superfamily
H9S87_04925	COG2732	(Barnase) inhibitor
H9S87_04930	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_04935	COG4605	iron ion homeostasis
H9S87_04940	COG4604	ABC transporter, ATP-binding protein
H9S87_04945	COG4607	ABC-type enterochelin transport system periplasmic component
H9S87_04950	COG1316	TRANSCRIPTIONal
H9S87_04960	COG0398	Pfam SNARE associated Golgi protein
H9S87_04965	COG0681	Belongs to the peptidase S26 family
H9S87_04970	COG3180	Ammonia monooxygenase
H9S87_04985	COG2259	Doxx family
H9S87_04990	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H9S87_04995	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H9S87_05000	COG1074	ATP-dependent DNA helicase activity
H9S87_05005	COG0420	3'-5' exonuclease activity
H9S87_05010	COG0419	ATPase involved in DNA repair
H9S87_05015	COG1403	HNH endonuclease
H9S87_05055	COG5337	Spore coat protein CotH
H9S87_05065	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9S87_05080	COG0367	asparagine synthase
H9S87_05095	COG1562	ergosterol biosynthetic process
H9S87_05100	COG0534	Mate efflux family protein
H9S87_05105	COG2207	Transcriptional regulator
H9S87_05105	COG1917	Cupin 2, conserved barrel domain protein
H9S87_05130	COG0076	glutamate decarboxylase activity
H9S87_05160	COG0646	methionine synthase
H9S87_05160	COG1410	methionine synthase
H9S87_05165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9S87_05165	COG0646	methionine synthase
H9S87_05170	COG1666	GTP binding
H9S87_05175	COG2996	Protein conserved in bacteria
H9S87_05180	COG1744	ABC transporter substrate-binding protein PnrA-like
H9S87_05185	COG0840	transmembrane signaling receptor activity
H9S87_05190	COG1307	EDD domain protein, DegV family
H9S87_05195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9S87_05215	COG0561	phosphatase activity
H9S87_05220	COG1073	alpha beta
H9S87_05225	COG2151	metal-sulfur cluster biosynthetic enzyme
H9S87_05235	COG2271	Major facilitator Superfamily
H9S87_05240	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9S87_05245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H9S87_05250	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9S87_05255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9S87_05260	COG0505	Belongs to the CarA family
H9S87_05265	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9S87_05270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9S87_05280	COG2814	Major facilitator Superfamily
H9S87_05290	COG2267	carboxylic ester hydrolase activity
H9S87_05300	COG1744	ABC transporter substrate-binding protein PnrA-like
H9S87_05315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9S87_05320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9S87_05325	COG5504	Zn-dependent protease
H9S87_05330	COG0444	Belongs to the ABC transporter superfamily
H9S87_05335	COG4608	Belongs to the ABC transporter superfamily
H9S87_05345	COG0601	transmembrane transport
H9S87_05350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9S87_05360	COG0180	Tryptophanyl-tRNA synthetase
H9S87_05365	COG4166	transmembrane transport
H9S87_05370	COG0601	transmembrane transport
H9S87_05375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9S87_05380	COG0444	Belongs to the ABC transporter superfamily
H9S87_05385	COG4608	Belongs to the ABC transporter superfamily
H9S87_05390	COG0456	acetyltransferase
H9S87_05395	COG1393	Belongs to the ArsC family
H9S87_05400	COG0861	Integral membrane protein TerC family
H9S87_05405	COG4862	establishment of competence for transformation
H9S87_05410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9S87_05420	COG1164	Oligoendopeptidase f
H9S87_05425	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H9S87_05430	COG2346	COG2346, Truncated hemoglobins
H9S87_05435	COG0741	lytic transglycosylase activity
H9S87_05440	COG4116	CYTH
H9S87_05450	COG2357	RelA SpoT domain protein
H9S87_05455	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9S87_05460	COG0564	pseudouridine synthase activity
H9S87_05465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9S87_05470	COG0569	domain protein
H9S87_05470	COG0475	glutathione-regulated potassium exporter activity
H9S87_05475	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9S87_05480	COG0352	thiamine-phosphate diphosphorylase activity
H9S87_05490	COG2104	thiamine diphosphate biosynthetic process
H9S87_05495	COG2022	thiamine diphosphate biosynthetic process
H9S87_05500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9S87_05505	COG0351	phosphomethylpyrimidine kinase
H9S87_05510	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9S87_05565	COG0210	DNA helicase
H9S87_05580	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H9S87_05585	COG2382	esterase
H9S87_05590	COG0626	cystathionine gamma-synthase activity
H9S87_05595	COG0626	cystathionine gamma-synthase activity
H9S87_05640	COG0457	Tetratricopeptide repeat
H9S87_05660	COG3173	Aminoglycoside phosphotransferase
H9S87_05665	COG0583	DNA-binding transcription factor activity
H9S87_05680	COG0583	DNA-binding transcription factor activity
H9S87_05685	COG2807	transmembrane transport
H9S87_05695	COG0457	Tetratricopeptide repeat
H9S87_05710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9S87_05720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9S87_05725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9S87_05745	COG4195	phage-related replication protein
H9S87_05750	COG2856	Zn peptidase
H9S87_05755	COG3409	Peptidoglycan-binding domain 1 protein
H9S87_05755	COG5632	N-Acetylmuramoyl-L-alanine amidase
H9S87_05770	COG0306	phosphate transporter
H9S87_05775	COG1392	Phosphate transport regulator
H9S87_05785	COG0405	Gamma-glutamyltransferase
H9S87_05795	COG3775	system Galactitol-specific IIC component
H9S87_05815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9S87_05820	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9S87_05820	COG0022	dehydrogenase e1 component
H9S87_05825	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9S87_05830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9S87_05835	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_05840	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_05845	COG2390	Transcriptional regulator
H9S87_05855	COG0531	amino acid
H9S87_05860	COG0346	lactoylglutathione lyase activity
H9S87_05865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9S87_05870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9S87_05875	COG2362	D-Aminopeptidase
H9S87_05880	COG0601	transmembrane transport
H9S87_05885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9S87_05890	COG0444	Belongs to the ABC transporter superfamily
H9S87_05895	COG4166	transmembrane transport
H9S87_05900	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9S87_05905	COG4948	Mandelate Racemase Muconate Lactonizing
H9S87_05910	COG0791	NLP P60 protein
H9S87_05915	COG4608	Belongs to the ABC transporter superfamily
H9S87_05920	COG1834	amidinotransferase
H9S87_05925	COG1607	acyl-coa hydrolase
H9S87_05930	COG1695	Transcriptional regulator
H9S87_05945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9S87_05955	COG2076	Multidrug Resistance protein
H9S87_05960	COG2076	Multidrug Resistance protein
H9S87_05970	COG0788	formyltetrahydrofolate deformylase activity
H9S87_05975	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9S87_05980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9S87_05985	COG0457	Tetratricopeptide repeat
H9S87_05995	COG1764	response to oxidative stress
H9S87_06000	COG1846	Transcriptional regulator
H9S87_06005	COG1764	response to oxidative stress
H9S87_06010	COG0590	tRNA wobble adenosine to inosine editing
H9S87_06015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9S87_06020	COG1404	Belongs to the peptidase S8 family
H9S87_06025	COG0745	RESPONSE REGULATOR receiver
H9S87_06030	COG3850	Histidine kinase
H9S87_06030	COG5002	protein histidine kinase activity
H9S87_06035	COG3212	peptidase
H9S87_06040	COG3212	peptidase
H9S87_06045	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9S87_06055	COG2239	Acts as a magnesium transporter
H9S87_06070	COG0583	DNA-binding transcription factor activity
H9S87_06080	COG0789	Transcriptional regulator
H9S87_06095	COG1846	Transcriptional regulator
H9S87_06100	COG5001	Diguanylate cyclase
H9S87_06100	COG3300	MHYT domain
H9S87_06105	COG0586	Pfam SNARE associated Golgi protein
H9S87_06110	COG0861	Integral membrane protein TerC family
H9S87_06115	COG1191	sigma factor activity
H9S87_06135	COG0501	Belongs to the peptidase M48B family
H9S87_06140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9S87_06145	COG2323	membrane
H9S87_06160	COG3594	Acyltransferase
H9S87_06165	COG5002	protein histidine kinase activity
H9S87_06170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9S87_06175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H9S87_06180	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H9S87_06185	COG0436	Aminotransferase
H9S87_06190	COG1850	ribulose-bisphosphate carboxylase activity
H9S87_06195	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
H9S87_06200	COG0235	Class ii aldolase
H9S87_06205	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H9S87_06215	COG3852	Histidine kinase
H9S87_06220	COG1846	Transcriptional regulator
H9S87_06225	COG1360	Flagellar Motor Protein
H9S87_06230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9S87_06235	COG0542	response to heat
H9S87_06240	COG3949	Membrane
H9S87_06245	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9S87_06250	COG0720	synthase
H9S87_06255	COG0602	queuosine metabolic process
H9S87_06260	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9S87_06270	COG4873	Protein conserved in bacteria
H9S87_06280	COG3773	Cell wall hydrolase
H9S87_06285	COG2244	polysaccharide biosynthetic process
H9S87_06290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_06295	COG2217	Heavy metal translocating P-type atpase
H9S87_06300	COG0006	proline dipeptidase activity
H9S87_06310	COG1609	Transcriptional regulator
H9S87_06315	COG3711	transcriptional antiterminator
H9S87_06320	COG2190	(PTS) system
H9S87_06320	COG1263	PTS System
H9S87_06320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_06325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_06330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9S87_06340	COG1533	DNA photolyase activity
H9S87_06345	COG0840	transmembrane signaling receptor activity
H9S87_06355	COG2084	Dehydrogenase
H9S87_06360	COG2340	Cysteine-rich secretory protein family
H9S87_06365	COG0768	penicillin binding
H9S87_06370	COG4191	Histidine kinase
H9S87_06375	COG0436	Aminotransferase
H9S87_06380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9S87_06390	COG1714	RDD family
H9S87_06400	COG0784	Response regulator, receiver
H9S87_06400	COG0835	chemotaxis
H9S87_06415	COG2814	Major facilitator Superfamily
H9S87_06420	COG1376	ErfK ybiS ycfS ynhG family protein
H9S87_06425	COG1408	metallophosphoesterase
H9S87_06430	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_06435	COG2200	EAL domain
H9S87_06440	COG3546	catalase activity
H9S87_06445	COG4703	Protein of unknown function (DUF1797)
H9S87_06450	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H9S87_06460	COG0517	IMP dehydrogenase activity
H9S87_06465	COG0583	DNA-binding transcription factor activity
H9S87_06470	COG0716	FMN binding
H9S87_06480	COG0716	FMN binding
H9S87_06485	COG2171	N-acyltransferase activity
H9S87_06490	COG1473	amidohydrolase
H9S87_06500	COG0668	transmembrane transport
H9S87_06505	COG0450	alkyl hydroperoxide reductase
H9S87_06510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_06525	COG0746	molybdenum cofactor guanylyltransferase activity
H9S87_06530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9S87_06535	COG0303	'Molybdopterin
H9S87_06540	COG1763	Mo-molybdopterin cofactor biosynthetic process
H9S87_06545	COG0314	molybdopterin synthase activity
H9S87_06550	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H9S87_06565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9S87_06570	COG1136	(ABC) transporter
H9S87_06575	COG0577	efflux transmembrane transporter activity
H9S87_06580	COG1349	DNA-binding transcription factor activity
H9S87_06585	COG1105	Belongs to the carbohydrate kinase PfkB family
H9S87_06590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_06590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_06590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_06605	COG0488	(ABC) transporter
H9S87_06610	COG2309	aminopeptidase activity
H9S87_06620	COG1077	Cell shape determining protein MreB Mrl
H9S87_06625	COG2002	toxin-antitoxin pair type II binding
H9S87_06630	COG3852	Histidine kinase
H9S87_06635	COG2105	PFAM AIG2 family protein
H9S87_06635	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H9S87_06640	COG0569	domain protein
H9S87_06645	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H9S87_06650	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9S87_06655	COG5503	Protein of unknown function (DUF1447)
H9S87_06660	COG0561	phosphatase activity
H9S87_06665	COG0242	peptide deformylase activity
H9S87_06680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9S87_06685	COG0022	dehydrogenase e1 component
H9S87_06690	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9S87_06695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9S87_06700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_06710	COG1982	Orn Lys Arg decarboxylase major
H9S87_06715	COG4476	Belongs to the UPF0223 family
H9S87_06720	COG4493	Belongs to the UPF0637 family
H9S87_06730	COG0483	inositol monophosphate 1-phosphatase activity
H9S87_06745	COG1217	gtp-binding protein TYPA
H9S87_06755	COG4896	Protein conserved in bacteria
H9S87_06765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9S87_06770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H9S87_06775	COG2066	Belongs to the glutaminase family
H9S87_06780	COG4838	Belongs to the UPF0358 family
H9S87_06785	COG0772	Belongs to the SEDS family
H9S87_06790	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H9S87_06795	COG0415	Belongs to the DNA photolyase family
H9S87_06800	COG1612	heme a metabolic process
H9S87_06805	COG0109	protoheme IX farnesyltransferase activity
H9S87_06810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9S87_06810	COG2010	Cytochrome c
H9S87_06815	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9S87_06820	COG1845	cytochrome c oxidase, subunit III
H9S87_06825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H9S87_06830	COG3336	cytochrome c oxidase
H9S87_06840	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H9S87_06845	COG2340	Cysteine-rich secretory protein family
H9S87_06865	COG3679	Belongs to the UPF0342 family
H9S87_06870	COG4471	UPF0298 protein
H9S87_06875	COG0742	ribosomal rna small subunit methyltransferase
H9S87_06880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9S87_06885	COG3314	Sporulation integral membrane protein YlbJ
H9S87_06890	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9S87_06895	COG3480	Lon protease (S16) C-terminal proteolytic domain
H9S87_06905	COG1399	metal-binding, possibly nucleic acid-binding protein
H9S87_06910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9S87_06920	COG0454	-acetyltransferase
H9S87_06925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9S87_06930	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H9S87_06935	COG2001	Belongs to the MraZ family
H9S87_06940	COG0275	rRNA processing
H9S87_06945	COG4839	cell division protein FtsL
H9S87_06950	COG0768	penicillin binding
H9S87_06955	COG0768	penicillin binding
H9S87_06960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9S87_06965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9S87_06970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9S87_06975	COG0772	Belongs to the SEDS family
H9S87_06980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9S87_06985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9S87_06990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9S87_06995	COG3879	Bacterial protein of unknown function (DUF881)
H9S87_07000	COG3879	Bacterial protein of unknown function (DUF881)
H9S87_07005	COG3856	small basic protein
H9S87_07010	COG0849	cell division
H9S87_07015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9S87_07020	COG1404	Belongs to the peptidase S8 family
H9S87_07020	COG4412	M6 family metalloprotease domain protein
H9S87_07030	COG1191	sigma factor activity
H9S87_07035	COG1191	sigma factor activity
H9S87_07040	COG2390	Transcriptional regulator
H9S87_07055	COG3730	PTS system glucitol sorbitol-specific
H9S87_07060	COG3732	PTS system glucitol sorbitol-specific
H9S87_07070	COG1119	ATPase activity
H9S87_07075	COG1873	PFAM PRC-barrel domain
H9S87_07080	COG1496	oxidoreductase activity
H9S87_07085	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9S87_07090	COG1799	cell septum assembly
H9S87_07095	COG0762	integral membrane protein
H9S87_07100	COG2302	S4 RNA-binding domain
H9S87_07105	COG3599	regulation of cell shape
H9S87_07110	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9S87_07115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9S87_07120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9S87_07125	COG0564	pseudouridine synthase activity
H9S87_07130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H9S87_07135	COG2233	PERMEase
H9S87_07140	COG0540	Belongs to the ATCase OTCase family
H9S87_07145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H9S87_07150	COG0505	Belongs to the CarA family
H9S87_07155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9S87_07160	COG0543	2 iron, 2 sulfur cluster binding
H9S87_07165	COG0167	dihydroorotate dehydrogenase activity
H9S87_07170	COG0284	orotidine-5'-phosphate decarboxylase activity
H9S87_07175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9S87_07185	COG0175	sulfate reduction
H9S87_07190	COG0306	phosphate transporter
H9S87_07195	COG2046	Belongs to the sulfate adenylyltransferase family
H9S87_07200	COG0529	Catalyzes the synthesis of activated sulfate
H9S87_07205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9S87_07210	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H9S87_07215	COG1648	precorrin-2 dehydrogenase activity
H9S87_07225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H9S87_07230	COG1561	YicC-like family, N-terminal region
H9S87_07235	COG2052	Domain of unknown function (DUF370)
H9S87_07240	COG0194	GDP metabolic process
H9S87_07245	COG1758	RNA polymerase activity
H9S87_07250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9S87_07255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9S87_07260	COG0242	peptide deformylase activity
H9S87_07265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9S87_07270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9S87_07270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9S87_07275	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9S87_07280	COG0631	protein serine/threonine phosphatase activity
H9S87_07285	COG2815	serine threonine protein kinase
H9S87_07285	COG0515	serine threonine protein kinase
H9S87_07290	COG1162	GTPase activity
H9S87_07295	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9S87_07300	COG1564	THIamine pyrophosphokinase
H9S87_07310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9S87_07315	COG1302	Protein conserved in bacteria
H9S87_07320	COG1461	Dihydroxyacetone kinase
H9S87_07325	COG1760	l-serine dehydratase
H9S87_07330	COG1760	l-serine dehydratase
H9S87_07335	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9S87_07340	COG1349	DNA-binding transcription factor activity
H9S87_07345	COG0416	fatty acid biosynthetic process
H9S87_07350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H9S87_07355	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_07360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9S87_07370	COG1196	nuclear chromosome segregation
H9S87_07375	COG0552	protein localization to endoplasmic reticulum
H9S87_07380	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H9S87_07385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9S87_07390	COG0228	four-way junction DNA binding
H9S87_07395	COG1837	Belongs to the UPF0109 family
H9S87_07405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9S87_07410	COG0336	Belongs to the RNA methyltransferase TrmD family
H9S87_07415	COG0335	large ribosomal subunit rRNA binding
H9S87_07420	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9S87_07425	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9S87_07435	COG2257	FlhB HrpN YscU SpaS Family
H9S87_07440	COG0045	succinate-CoA ligase (ADP-forming) activity
H9S87_07445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9S87_07450	COG0758	DNA mediated transformation
H9S87_07455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9S87_07460	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H9S87_07465	COG4974	Belongs to the 'phage' integrase family
H9S87_07470	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H9S87_07475	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9S87_07480	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H9S87_07485	COG1815	bacterial-type flagellum-dependent cell motility
H9S87_07490	COG1558	bacterial-type flagellum-dependent cell motility
H9S87_07495	COG1677	Flagellar hook-basal body complex protein FliE
H9S87_07500	COG1766	The M ring may be actively involved in energy transduction
H9S87_07505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9S87_07510	COG1317	bacterial-type flagellum organization
H9S87_07515	COG1157	protein secretion by the type III secretion system
H9S87_07520	COG2882	bacterial-type flagellum organization
H9S87_07525	COG3334	PFAM MgtE intracellular
H9S87_07530	COG3144	bacterial-type flagellum assembly
H9S87_07535	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9S87_07540	COG4786	Flagellar basal body rod
H9S87_07545	COG1582	Flagellar protein (FlbD)
H9S87_07550	COG1580	Controls the rotational direction of flagella during chemotaxis
H9S87_07555	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9S87_07560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9S87_07560	COG1776	CheC inhibitor of MCP methylation
H9S87_07565	COG2201	protein-glutamate methylesterase activity
H9S87_07570	COG3190	flagellar
H9S87_07575	COG1338	Plays a role in the flagellum-specific transport system
H9S87_07580	COG1987	bacterial-type flagellum assembly
H9S87_07585	COG1684	flagellar biosynthetic protein fliR
H9S87_07590	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9S87_07595	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9S87_07600	COG1419	protein localization to endoplasmic reticulum
H9S87_07605	COG0455	bacterial-type flagellum organization
H9S87_07610	COG2201	protein-glutamate methylesterase activity
H9S87_07615	COG2198	Histidine kinase
H9S87_07615	COG0643	Histidine kinase
H9S87_07620	COG0835	chemotaxis
H9S87_07625	COG1776	CheC inhibitor of MCP methylation
H9S87_07635	COG1191	sigma factor activity
H9S87_07645	COG0052	Belongs to the universal ribosomal protein uS2 family
H9S87_07650	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9S87_07655	COG0528	UMP kinase activity
H9S87_07660	COG0233	cytoplasmic translational termination
H9S87_07665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9S87_07670	COG4589	Belongs to the CDS family
H9S87_07675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9S87_07680	COG0750	zinc metalloprotease
H9S87_07685	COG0442	prolyl-tRNA aminoacylation
H9S87_07690	COG2176	DNA-directed DNA polymerase activity
H9S87_07705	COG3693	PFAM glycoside hydrolase, family 10
H9S87_07715	COG0779	Required for maturation of 30S ribosomal subunits
H9S87_07720	COG0195	Participates in both transcription termination and antitermination
H9S87_07725	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H9S87_07730	COG1358	cellular component organization or biogenesis
H9S87_07735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9S87_07740	COG1550	Protein conserved in bacteria
H9S87_07745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9S87_07750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9S87_07755	COG0196	riboflavin kinase activity
H9S87_07760	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9S87_07765	COG1185	polyribonucleotide nucleotidyltransferase activity
H9S87_07770	COG0726	polysaccharide deacetylase
H9S87_07775	COG0612	Peptidase, M16
H9S87_07785	COG1873	PFAM PRC-barrel domain
H9S87_07790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9S87_07795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9S87_07800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9S87_07805	COG0527	aspartate kinase activity
H9S87_07815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H9S87_07820	COG0740	serine-type endopeptidase activity
H9S87_07830	COG4980	gas vesicle protein
H9S87_07830	COG1674	ftsk spoiiie
H9S87_07835	COG2188	Transcriptional regulator
H9S87_07840	COG2814	Major facilitator Superfamily
H9S87_07845	COG2409	Drug exporters of the RND superfamily
H9S87_07845	COG1033	growth of symbiont in host cell
H9S87_07850	COG0612	Peptidase, M16
H9S87_07855	COG0612	Peptidase, M16
H9S87_07865	COG1033	growth of symbiont in host cell
H9S87_07865	COG2409	Drug exporters of the RND superfamily
H9S87_07870	COG0300	oxidoreductase activity
H9S87_07885	COG1426	Protein conserved in bacteria
H9S87_07890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9S87_07895	COG1058	Belongs to the CinA family
H9S87_07895	COG1546	Belongs to the CinA family
H9S87_07900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9S87_07905	COG1418	mRNA catabolic process
H9S87_07910	COG1692	metallophosphoesterase
H9S87_07915	COG2359	stage V sporulation protein S
H9S87_07920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9S87_07925	COG1063	alcohol dehydrogenase
H9S87_07930	COG0156	8-amino-7-oxononanoate synthase activity
H9S87_07940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9S87_07945	COG4550	Control of competence regulator ComK, YlbF/YmcA
H9S87_07955	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9S87_07960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9S87_07975	COG1329	Transcriptional regulator
H9S87_07980	COG4195	phage-related replication protein
H9S87_07985	COG0457	Tetratricopeptide repeat
H9S87_07990	COG1404	Belongs to the peptidase S8 family
H9S87_07995	COG4195	phage-related replication protein
H9S87_08000	COG1764	response to oxidative stress
H9S87_08005	COG2076	Multidrug Resistance protein
H9S87_08030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9S87_08035	COG1923	regulation of RNA biosynthetic process
H9S87_08050	COG1780	Probably involved in ribonucleotide reductase function
H9S87_08055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9S87_08060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9S87_08065	COG4112	unkown
H9S87_08075	COG0464	growth
H9S87_08080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9S87_08085	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H9S87_08090	COG0789	Transcriptional regulator
H9S87_08095	COG0174	glutamine synthetase
H9S87_08105	COG0457	Tetratricopeptide repeat
H9S87_08110	COG5444	nuclease activity
H9S87_08135	COG5646	InterPro IPR014922
H9S87_08160	COG0457	Tetratricopeptide repeat
H9S87_08170	COG3619	membrane
H9S87_08175	COG3285	dna ligase
H9S87_08175	COG1793	dna ligase
H9S87_08180	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H9S87_08185	COG4876	unkown
H9S87_08195	COG1959	2 iron, 2 sulfur cluster binding
H9S87_08200	COG0702	epimerase
H9S87_08205	COG0247	lactate metabolic process
H9S87_08210	COG1139	Iron-sulfur cluster binding protein
H9S87_08215	COG1556	Lactate utilization protein
H9S87_08240	COG1309	transcriptional regulator
H9S87_08245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9S87_08245	COG2124	cytochrome p450
H9S87_08250	COG3591	Belongs to the peptidase S1B family
H9S87_08255	COG3209	COG3209 Rhs family protein
H9S87_08260	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_08275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9S87_08280	COG1388	LysM domain
H9S87_08285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9S87_08290	COG4224	UPF0291 protein
H9S87_08295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9S87_08305	COG3763	UPF0154 protein
H9S87_08315	COG0785	Cytochrome C biogenesis protein
H9S87_08320	COG4846	Membrane protein involved in cytochrome C biogenesis
H9S87_08330	COG0071	Belongs to the small heat shock protein (HSP20) family
H9S87_08345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H9S87_08350	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_08370	COG0824	Thioesterase
H9S87_08380	COG4841	protein insertion into membrane
H9S87_08385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9S87_08390	COG1832	CoA-binding protein
H9S87_08395	COG0187	DNA topoisomerase II activity
H9S87_08400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9S87_08410	COG0738	Major facilitator superfamily
H9S87_08430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9S87_08435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H9S87_08440	COG0640	Transcriptional regulator
H9S87_08445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9S87_08450	COG0251	oxidation-reduction process
H9S87_08495	COG0657	acetylesterase activity
H9S87_08510	COG2205	protein histidine kinase activity
H9S87_08515	COG0745	RESPONSE REGULATOR receiver
H9S87_08525	COG3507	Belongs to the glycosyl hydrolase 43 family
H9S87_08530	COG1012	belongs to the aldehyde dehydrogenase family
H9S87_08535	COG1486	melibiose metabolic process
H9S87_08540	COG0395	ABC-type sugar transport system, permease component
H9S87_08545	COG1175	transmembrane transport
H9S87_08550	COG1653	transport
H9S87_08555	COG1609	Transcriptional regulator
H9S87_08560	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9S87_08575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_08590	COG1404	Belongs to the peptidase S8 family
H9S87_08595	COG1846	Transcriptional regulator
H9S87_08600	COG2814	Major facilitator Superfamily
H9S87_08610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_08610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_08610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_08615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_08615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_08615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9S87_08620	COG1105	Belongs to the carbohydrate kinase PfkB family
H9S87_08630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9S87_08660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9S87_08665	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9S87_08670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9S87_08675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9S87_08680	COG1024	Enoyl-CoA hydratase
H9S87_08685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9S87_08690	COG0511	ligase activity, forming carbon-carbon bonds
H9S87_08695	COG0439	Biotin carboxylase
H9S87_08700	COG0318	PFAM AMP-dependent synthetase and ligase
H9S87_08705	COG1960	acyl-CoA dehydrogenase activity
H9S87_08710	COG1649	PFAM Uncharacterised BCR, COG1649
H9S87_08715	COG2365	Tyrosine phosphatase family
H9S87_08720	COG1349	DNA-binding transcription factor activity
H9S87_08730	COG3835	regulator
H9S87_08735	COG0277	FAD linked oxidase domain protein
H9S87_08740	COG0247	lactate metabolic process
H9S87_08770	COG0166	Belongs to the GPI family
H9S87_08775	COG0586	Pfam SNARE associated Golgi protein
H9S87_08780	COG1587	Uroporphyrinogen-III synthase
H9S87_08790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9S87_08805	COG0534	Mate efflux family protein
H9S87_08810	COG2027	D-alanyl-D-alanine carboxypeptidase
H9S87_08815	COG4677	pectinesterase activity
H9S87_08820	COG2323	membrane
H9S87_08825	COG2146	nitrite reductase [NAD(P)H] activity
H9S87_08830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9S87_08835	COG0243	molybdopterin cofactor binding
H9S87_08840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9S87_08845	COG2223	nitrite transmembrane transporter activity
H9S87_08850	COG0493	'glutamate synthase
H9S87_08855	COG0067	glutamate synthase
H9S87_08855	COG0069	glutamate synthase activity
H9S87_08855	COG0070	glutamate synthase
H9S87_08860	COG0583	DNA-binding transcription factor activity
H9S87_08870	COG1132	(ABC) transporter
H9S87_08880	COG0454	-acetyltransferase
H9S87_08885	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9S87_08890	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9S87_08905	COG0243	molybdopterin cofactor binding
H9S87_08915	COG1070	Carbohydrate kinase
H9S87_08920	COG2115	Belongs to the xylose isomerase family
H9S87_08925	COG1940	carbohydrate kinase activity
H9S87_08935	COG2211	Major facilitator Superfamily
H9S87_08940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9S87_08945	COG1994	Peptidase M50
H9S87_08965	COG1309	transcriptional regulator
H9S87_08970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9S87_08975	COG3708	Transcriptional regulator
H9S87_08980	COG2378	regulation of single-species biofilm formation
H9S87_08990	COG0640	Transcriptional regulator
H9S87_08995	COG0531	amino acid
H9S87_09000	COG0741	lytic transglycosylase activity
H9S87_09015	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H9S87_09020	COG2079	MmgE PrpD family protein
H9S87_09025	COG0372	Belongs to the citrate synthase family
H9S87_09030	COG2322	membrane
H9S87_09040	COG3584	3D domain protein
H9S87_09040	COG1388	LysM domain
H9S87_09045	COG0514	ATP-dependent DNA helicase (RecQ)
H9S87_09055	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9S87_09080	COG1012	belongs to the aldehyde dehydrogenase family
H9S87_09085	COG1657	PFAM Prenyltransferase squalene oxidase
H9S87_09090	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9S87_09095	COG0385	Bile acid
H9S87_09100	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9S87_09105	COG0567	Dehydrogenase, E1 component
H9S87_09110	COG4548	von Willebrand factor, type A
H9S87_09115	COG0714	Associated with various cellular activities
H9S87_09120	COG2032	superoxide dismutase activity
H9S87_09125	COG1388	LysM domain
H9S87_09125	COG0791	NLP P60 protein
H9S87_09130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H9S87_09135	COG0534	Mate efflux family protein
H9S87_09140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9S87_09145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9S87_09155	COG2962	Rard protein
H9S87_09170	COG1733	regulation of RNA biosynthetic process
H9S87_09175	COG0778	Nitroreductase
H9S87_09185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9S87_09190	COG0793	Belongs to the peptidase S41A family
H9S87_09190	COG3409	Peptidoglycan-binding domain 1 protein
H9S87_09195	COG2226	methyltransferase
H9S87_09205	COG1876	peptidase activity
H9S87_09210	COG0813	purine-nucleoside phosphorylase activity
H9S87_09220	COG0671	phosphoesterase, PA-phosphatase related
H9S87_09235	COG4479	Belongs to the UPF0346 family
H9S87_09245	COG1509	lysine 2,3-aminomutase activity
H9S87_09250	COG3829	transcription factor binding
H9S87_09255	COG0463	Glycosyl transferase, family 2
H9S87_09270	COG4641	Protein conserved in bacteria
H9S87_09280	COG1086	Polysaccharide biosynthesis protein
H9S87_09285	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9S87_09290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9S87_09295	COG1846	Transcriptional regulator
H9S87_09315	COG4698	Protein conserved in bacteria
H9S87_09320	COG2755	lipolytic protein G-D-S-L family
H9S87_09325	COG1999	signal sequence binding
H9S87_09340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9S87_09345	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9S87_09350	COG1272	protein, Hemolysin III
H9S87_09355	COG0204	Acyl-transferase
H9S87_09360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H9S87_09365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9S87_09370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9S87_09380	COG2136	Putative SAM-dependent methyltransferase
H9S87_09380	COG2521	methyltransferase
H9S87_09390	COG0129	dihydroxy-acid dehydratase activity
H9S87_09395	COG1413	lyase activity
H9S87_09400	COG1418	mRNA catabolic process
H9S87_09405	COG0386	Belongs to the glutathione peroxidase family
H9S87_09410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H9S87_09415	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H9S87_09420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9S87_09430	COG1278	Cold shock
H9S87_09445	COG0328	RNA-DNA hybrid ribonuclease activity
H9S87_09450	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9S87_09455	COG0328	RNA-DNA hybrid ribonuclease activity
H9S87_09465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9S87_09475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H9S87_09485	COG1755	Isoprenylcysteine carboxyl methyltransferase
H9S87_09490	COG3424	synthase
H9S87_09495	COG2233	PERMEase
H9S87_09500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9S87_09505	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9S87_09510	COG1199	ATP-dependent helicase activity
H9S87_09520	COG0116	Belongs to the methyltransferase superfamily
H9S87_09530	COG3599	regulation of cell shape
H9S87_09535	COG4474	Belongs to the UPF0398 family
H9S87_09545	COG3359	exonuclease
H9S87_09550	COG1111	helicase
H9S87_09550	COG1205	dead DEAH box helicase
H9S87_09555	COG1902	pentaerythritol trinitrate reductase activity
H9S87_09560	COG2190	(PTS) system
H9S87_09565	COG0071	Belongs to the small heat shock protein (HSP20) family
H9S87_09595	COG3331	DNA recombination
H9S87_09600	COG4499	WXG100 protein secretion system (Wss), protein YukC
H9S87_09600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9S87_09610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9S87_09615	COG3935	DnaD domain protein
H9S87_09620	COG0017	Asparaginyl-tRNA synthetase
H9S87_09625	COG5353	protein conserved in bacteria
H9S87_09635	COG1199	ATP-dependent helicase activity
H9S87_09635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9S87_09640	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H9S87_09645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9S87_09650	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9S87_09660	COG0617	tRNA 3'-terminal CCA addition
H9S87_09665	COG0438	transferase activity, transferring glycosyl groups
H9S87_09670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H9S87_09675	COG1803	Methylglyoxal synthase
H9S87_09680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9S87_09685	COG1694	Mazg nucleotide pyrophosphohydrolase
H9S87_09690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9S87_09700	COG4347	Protein of unknown function (DUF1405)
H9S87_09705	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9S87_09705	COG2010	Cytochrome c
H9S87_09710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9S87_09715	COG0723	plastoquinol--plastocyanin reductase activity
H9S87_09725	COG5582	Belongs to the UPF0302 family
H9S87_09730	COG0457	Tetratricopeptide repeat
H9S87_09735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9S87_09740	COG0287	Prephenate dehydrogenase
H9S87_09745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9S87_09750	COG0159	tryptophan synthase activity
H9S87_09755	COG0133	tryptophan synthase activity
H9S87_09760	COG0135	phosphoribosylanthranilate isomerase activity
H9S87_09765	COG0134	indole-3-glycerol-phosphate synthase activity
H9S87_09770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9S87_09780	COG4401	Chorismate mutase type I
H9S87_09785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9S87_09790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9S87_09795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9S87_09800	COG0105	UTP biosynthetic process
H9S87_09805	COG0142	geranyltranstransferase activity
H9S87_09810	COG2226	methyltransferase
H9S87_09815	COG0142	geranyltranstransferase activity
H9S87_09825	COG0302	gtp cyclohydrolase
H9S87_09830	COG0776	regulation of translation
H9S87_09835	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H9S87_09850	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9S87_09855	COG1160	GTP binding
H9S87_09880	COG1304	FMN binding
H9S87_09885	COG0539	negative regulation of cytoplasmic translation
H9S87_09890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9S87_09900	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H9S87_09905	COG2959	enzyme of heme biosynthesis
H9S87_09910	COG3409	Peptidoglycan-binding domain 1 protein
H9S87_09910	COG3773	Cell wall hydrolase
H9S87_09915	COG2339	peptidase activity
H9S87_09920	COG0492	ferredoxin-NADP+ reductase activity
H9S87_09925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9S87_09930	COG4862	establishment of competence for transformation
H9S87_09935	COG1408	metallophosphoesterase
H9S87_09945	COG1388	LysM domain
H9S87_09950	COG1266	CAAX protease self-immunity
H9S87_09955	COG0514	ATP-dependent DNA helicase (RecQ)
H9S87_09960	COG4955	Helix-turn-helix domain
H9S87_09965	COG1141	Ferredoxin
H9S87_09970	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H9S87_09975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9S87_09980	COG3409	Peptidoglycan-binding domain 1 protein
H9S87_09980	COG5632	N-Acetylmuramoyl-L-alanine amidase
H9S87_09990	COG1595	DNA-templated transcription, initiation
H9S87_09995	COG5002	protein histidine kinase activity
H9S87_10000	COG0745	RESPONSE REGULATOR receiver
H9S87_10005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9S87_10010	COG1333	cytochrome c biogenesis protein
H9S87_10015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_10020	COG1187	pseudouridine synthase activity
H9S87_10025	COG0700	Nucleoside recognition
H9S87_10030	COG2715	membrane protein required for spore maturation
H9S87_10035	COG1686	Belongs to the peptidase S11 family
H9S87_10045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H9S87_10050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H9S87_10060	COG1547	Domain of unknown function (DUF309)
H9S87_10065	COG0456	acetyltransferase
H9S87_10070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9S87_10075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9S87_10075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9S87_10080	COG0307	riboflavin synthase, alpha
H9S87_10100	COG2814	Major facilitator Superfamily
H9S87_10105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9S87_10110	COG4086	secreted protein
H9S87_10115	COG0019	diaminopimelate decarboxylase activity
H9S87_10120	COG0697	spore germination
H9S87_10135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9S87_10155	COG1191	sigma factor activity
H9S87_10160	COG2172	sigma factor antagonist activity
H9S87_10170	COG1686	Belongs to the peptidase S11 family
H9S87_10175	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H9S87_10180	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9S87_10185	COG4974	Belongs to the 'phage' integrase family
H9S87_10195	COG0735	belongs to the Fur family
H9S87_10200	COG1300	Membrane
H9S87_10205	COG1404	Belongs to the peptidase S8 family
H9S87_10215	COG2153	protein acetylation
H9S87_10220	COG1379	DNA repair
H9S87_10225	COG0494	nUDIX hydrolase
H9S87_10230	COG0667	Aldo Keto reductase
H9S87_10245	COG1073	alpha beta
H9S87_10250	COG0457	Tetratricopeptide repeat
H9S87_10260	COG4918	Iron-sulphur cluster biosynthesis
H9S87_10265	COG4305	rare lipoprotein A
H9S87_10270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H9S87_10270	COG0456	acetyltransferase
H9S87_10275	COG0456	acetyltransferase
H9S87_10285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9S87_10295	COG2211	Major facilitator Superfamily
H9S87_10300	COG1072	(Pantothenic acid kinase))
H9S87_10310	COG0300	oxidoreductase activity
H9S87_10315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9S87_10320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9S87_10330	COG4187	Peptidase family M20/M25/M40
H9S87_10335	COG1902	pentaerythritol trinitrate reductase activity
H9S87_10340	COG0596	Alpha beta hydrolase
H9S87_10345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9S87_10350	COG1234	tRNA 3'-trailer cleavage
H9S87_10355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9S87_10360	COG2188	Transcriptional regulator
H9S87_10365	COG2723	6-phospho-beta-galactosidase activity
H9S87_10370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9S87_10375	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9S87_10380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9S87_10385	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_10395	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9S87_10400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9S87_10410	COG0706	membrane insertase activity
H9S87_10420	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9S87_10425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9S87_10430	COG0346	lactoylglutathione lyase activity
H9S87_10440	COG1376	ErfK ybiS ycfS ynhG family protein
H9S87_10445	COG4129	membrane
H9S87_10450	COG1126	abc transporter atp-binding protein
H9S87_10455	COG0765	amino acid transport
H9S87_10460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_10470	COG1597	lipid kinase activity
H9S87_10480	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9S87_10485	COG0022	dehydrogenase e1 component
H9S87_10490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9S87_10495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9S87_10500	COG3426	butyrate kinase activity
H9S87_10505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9S87_10510	COG0280	phosphate acetyltransferase
H9S87_10515	COG3829	transcription factor binding
H9S87_10515	COG3290	protein histidine kinase activity
H9S87_10525	COG0584	glycerophosphoryl diester phosphodiesterase
H9S87_10530	COG0457	Tetratricopeptide repeat
H9S87_10535	COG0745	RESPONSE REGULATOR receiver
H9S87_10540	COG0750	zinc metalloprotease
H9S87_10545	COG0497	DNA recombination
H9S87_10550	COG1438	arginine binding
H9S87_10555	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H9S87_10560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9S87_10565	COG0142	geranyltranstransferase activity
H9S87_10570	COG1722	exodeoxyribonuclease VII activity
H9S87_10575	COG1570	exodeoxyribonuclease VII activity
H9S87_10580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9S87_10585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9S87_10590	COG1302	Protein conserved in bacteria
H9S87_10595	COG0439	Biotin carboxylase
H9S87_10600	COG0511	ligase activity, forming carbon-carbon bonds
H9S87_10640	COG3854	ATPases associated with a variety of cellular activities
H9S87_10650	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9S87_10655	COG0006	proline dipeptidase activity
H9S87_10660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9S87_10670	COG3872	metal-dependent enzyme
H9S87_10680	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9S87_10685	COG1321	iron dependent repressor
H9S87_10690	COG0095	Lipoate-protein ligase
H9S87_10695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9S87_10700	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9S87_10705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9S87_10710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H9S87_10715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9S87_10740	COG0681	Belongs to the peptidase S26 family
H9S87_10775	COG4970	Tfp pilus assembly protein FimT
H9S87_10780	COG4537	Required for transformation and DNA binding
H9S87_10785	COG1459	type II secretion system
H9S87_10790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9S87_10795	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_10805	COG1393	Belongs to the ArsC family
H9S87_10815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9S87_10825	COG0011	TIGRFAM Protein of
H9S87_10830	COG2814	Major facilitator Superfamily
H9S87_10835	COG2866	Carboxypeptidase
H9S87_10840	COG1368	sulfuric ester hydrolase activity
H9S87_10845	COG1940	carbohydrate kinase activity
H9S87_10850	COG4483	Protein conserved in bacteria
H9S87_10855	COG0705	Rhomboid family
H9S87_10855	COG0457	Tetratricopeptide repeat
H9S87_10865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9S87_10870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9S87_10880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9S87_10885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9S87_10890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9S87_10895	COG0581	inorganic phosphate transmembrane transporter activity
H9S87_10900	COG0573	inorganic phosphate transmembrane transporter activity
H9S87_10905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9S87_10910	COG0768	penicillin binding
H9S87_10915	COG0477	Major facilitator Superfamily
H9S87_10920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9S87_10925	COG2839	Protein conserved in bacteria
H9S87_10930	COG5521	maltodextrose utilization protein MalA
H9S87_10935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9S87_10940	COG1388	LysM domain
H9S87_10945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9S87_10950	COG4709	membrane
H9S87_10955	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H9S87_10960	COG1940	carbohydrate kinase activity
H9S87_10965	COG0735	belongs to the Fur family
H9S87_10970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9S87_10975	COG1121	(ABC) transporter
H9S87_10980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9S87_10990	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H9S87_10995	COG0513	Belongs to the DEAD box helicase family
H9S87_11005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9S87_11010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9S87_11015	COG2384	SAM-dependent methyltransferase
H9S87_11020	COG2010	Cytochrome c
H9S87_11025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9S87_11030	COG0358	DNA primase activity
H9S87_11035	COG1671	Belongs to the UPF0178 family
H9S87_11040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H9S87_11045	COG0517	IMP dehydrogenase activity
H9S87_11050	COG0751	glycine-tRNA ligase activity
H9S87_11055	COG0752	glycyl-tRNA synthetase alpha subunit
H9S87_11060	COG1381	Involved in DNA repair and RecF pathway recombination
H9S87_11070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9S87_11075	COG0295	cytidine deaminase activity
H9S87_11080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9S87_11085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9S87_11090	COG1480	7TM receptor with intracellular HD hydrolase
H9S87_11095	COG1702	phosphate starvation-inducible protein PhoH
H9S87_11100	COG0561	phosphatase activity
H9S87_11115	COG4864	UPF0365 protein
H9S87_11120	COG1030	water channel activity
H9S87_11125	COG1610	YqeY-like protein
H9S87_11135	COG1283	sodium-dependent phosphate transmembrane transporter activity
H9S87_11140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9S87_11145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9S87_11150	COG2264	protein methyltransferase activity
H9S87_11155	COG0484	heat shock protein binding
H9S87_11160	COG0443	Heat shock 70 kDa protein
H9S87_11165	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9S87_11170	COG1420	regulation of RNA biosynthetic process
H9S87_11175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9S87_11180	COG0481	GTPase activity
H9S87_11190	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9S87_11195	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H9S87_11200	COG0268	Binds directly to 16S ribosomal RNA
H9S87_11205	COG1466	dna polymerase III delta subunit
H9S87_11215	COG0658	competence protein
H9S87_11215	COG2333	competence protein COMEC
H9S87_11220	COG2131	deaminase
H9S87_11225	COG1555	photosystem II stabilization
H9S87_11230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9S87_11235	COG2226	methyltransferase
H9S87_11240	COG0799	negative regulation of ribosome biogenesis
H9S87_11245	COG1713	HD superfamily hydrolase involved in NAD metabolism
H9S87_11250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9S87_11255	COG1534	Rna-binding protein
H9S87_11260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9S87_11265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H9S87_11270	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H9S87_11285	COG2755	lipolytic protein G-D-S-L family
H9S87_11295	COG0457	Tetratricopeptide repeat
H9S87_11305	COG1063	alcohol dehydrogenase
H9S87_11310	COG4221	oxidoreductase activity
H9S87_11315	COG0300	oxidoreductase activity
H9S87_11320	COG1902	pentaerythritol trinitrate reductase activity
H9S87_11325	COG0596	Alpha beta hydrolase
H9S87_11325	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9S87_11330	COG1309	transcriptional regulator
H9S87_11340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9S87_11355	COG0726	polysaccharide deacetylase
H9S87_11390	COG1122	ATPase activity
H9S87_11410	COG2160	L-arabinose isomerase activity
H9S87_11425	COG1609	Transcriptional regulator
H9S87_11435	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H9S87_11440	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H9S87_11445	COG1733	regulation of RNA biosynthetic process
H9S87_11450	COG0657	acetylesterase activity
H9S87_11465	COG1309	transcriptional regulator
H9S87_11470	COG0109	protoheme IX farnesyltransferase activity
H9S87_11475	COG2602	Beta-lactamase
H9S87_11480	COG1960	acyl-CoA dehydrogenase activity
H9S87_11485	COG1126	abc transporter atp-binding protein
H9S87_11490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_11495	COG0765	amino acid transport
H9S87_11505	COG3546	catalase activity
H9S87_11510	COG1063	alcohol dehydrogenase
H9S87_11520	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_11525	COG2226	methyltransferase
H9S87_11530	COG1063	alcohol dehydrogenase
H9S87_11535	COG2226	methyltransferase
H9S87_11560	COG0626	cystathionine gamma-synthase activity
H9S87_11565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9S87_11570	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9S87_11575	COG2226	methyltransferase
H9S87_11590	COG0768	penicillin binding
H9S87_11595	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9S87_11600	COG0572	uridine kinase
H9S87_11605	COG0826	peptidase U32
H9S87_11610	COG0826	peptidase U32
H9S87_11615	COG4122	O-methyltransferase activity
H9S87_11620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9S87_11625	COG0183	Belongs to the thiolase family
H9S87_11630	COG0318	PFAM AMP-dependent synthetase and ligase
H9S87_11635	COG1268	BioY protein
H9S87_11640	COG3906	Belongs to the UPF0473 family
H9S87_11645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9S87_11650	COG4472	Bacterial protein of unknown function (DUF965)
H9S87_11655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9S87_11660	COG0628	permease
H9S87_11665	COG1126	abc transporter atp-binding protein
H9S87_11670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_11675	COG0765	amino acid transport
H9S87_11680	COG0765	amino acid transport
H9S87_11695	COG3881	PFAM PRC-barrel domain
H9S87_11700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9S87_11705	COG0457	Tetratricopeptide repeat
H9S87_11710	COG0482	sulfurtransferase activity
H9S87_11715	COG1104	cysteine desulfurase activity
H9S87_11720	COG1959	2 iron, 2 sulfur cluster binding
H9S87_11725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9S87_11730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9S87_11745	COG0124	histidyl-tRNA synthetase
H9S87_11755	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9S87_11755	COG4991	sh3 domain protein
H9S87_11755	COG3103	Sh3 type 3 domain protein
H9S87_11760	COG1490	D-aminoacyl-tRNA deacylase activity
H9S87_11765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9S87_11770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9S87_11775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9S87_11775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H9S87_11780	COG5416	Lipopolysaccharide assembly protein A domain
H9S87_11785	COG0490	domain, Protein
H9S87_11790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9S87_11790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9S87_11800	COG2244	polysaccharide biosynthetic process
H9S87_11805	COG2323	membrane
H9S87_11815	COG1862	Preprotein translocase
H9S87_11820	COG0343	queuine tRNA-ribosyltransferase activity
H9S87_11825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9S87_11835	COG2255	four-way junction helicase activity
H9S87_11840	COG0632	four-way junction helicase activity
H9S87_11850	COG2112	serine threonine protein kinase
H9S87_11865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9S87_11880	COG1388	LysM domain
H9S87_11880	COG1388	LysM domain
H9S87_11885	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H9S87_11890	COG0157	Belongs to the NadC ModD family
H9S87_11895	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9S87_11900	COG1104	cysteine desulfurase activity
H9S87_11905	COG1827	regulation of RNA biosynthetic process
H9S87_11910	COG0077	Prephenate dehydratase
H9S87_11915	COG4492	Belongs to the UPF0735 family
H9S87_11920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9S87_11925	COG3290	protein histidine kinase activity
H9S87_11930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9S87_11935	COG2868	ribosomal protein
H9S87_11940	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9S87_11945	COG1994	Peptidase M50
H9S87_11950	COG0739	heme binding
H9S87_11955	COG2894	cell division
H9S87_11960	COG0850	regulation of cytokinetic process
H9S87_11965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H9S87_11975	COG1077	Cell shape determining protein MreB Mrl
H9S87_11980	COG2003	Belongs to the UPF0758 family
H9S87_11985	COG0424	maF-like protein
H9S87_11995	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9S87_12000	COG0285	dihydrofolate synthase activity
H9S87_12005	COG0525	valine-tRNA ligase activity
H9S87_12015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9S87_12020	COG1388	LysM domain
H9S87_12025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9S87_12030	COG0113	porphobilinogen synthase activity
H9S87_12035	COG1587	Uroporphyrinogen-III synthase
H9S87_12040	COG0181	hydroxymethylbilane synthase activity
H9S87_12045	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9S87_12050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9S87_12060	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9S87_12065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9S87_12070	COG0470	DNA polymerase III
H9S87_12070	COG1067	ATP-dependent peptidase activity
H9S87_12075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9S87_12080	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9S87_12085	COG0457	Tetratricopeptide repeat
H9S87_12085	COG1477	protein flavinylation
H9S87_12090	COG0066	3-isopropylmalate dehydratase activity
H9S87_12095	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9S87_12100	COG0473	3-isopropylmalate dehydrogenase activity
H9S87_12105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9S87_12110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9S87_12115	COG0440	acetolactate synthase activity
H9S87_12120	COG0028	Belongs to the TPP enzyme family
H9S87_12125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9S87_12130	COG2706	6-phosphogluconolactonase activity
H9S87_12135	COG3339	Conserved Protein
H9S87_12140	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H9S87_12145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9S87_12150	COG1696	Membrane protein involved in D-alanine export
H9S87_12155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9S87_12190	COG0622	Phosphoesterase
H9S87_12195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9S87_12200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9S87_12205	COG5401	PFAM Sporulation and spore germination
H9S87_12210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H9S87_12215	COG1846	Transcriptional regulator
H9S87_12220	COG2197	response regulator
H9S87_12225	COG2851	Citrate transporter
H9S87_12230	COG0583	DNA-binding transcription factor activity
H9S87_12235	COG2828	Protein conserved in bacteria
H9S87_12245	COG0824	Thioesterase
H9S87_12250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9S87_12255	COG1053	succinate dehydrogenase
H9S87_12260	COG2009	succinate dehydrogenase
H9S87_12265	COG1719	4-vinyl reductase, 4VR
H9S87_12270	COG0527	aspartate kinase activity
H9S87_12275	COG0322	excinuclease ABC activity
H9S87_12280	COG3118	belongs to the thioredoxin family
H9S87_12285	COG3534	alpha-L-arabinofuranosidase
H9S87_12290	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H9S87_12295	COG2086	electron transfer activity
H9S87_12300	COG1024	Enoyl-CoA hydratase
H9S87_12305	COG1309	transcriptional regulator
H9S87_12310	COG0318	PFAM AMP-dependent synthetase and ligase
H9S87_12320	COG3766	membrane
H9S87_12325	COG1193	negative regulation of DNA recombination
H9S87_12330	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9S87_12330	COG1796	DNA polymerase
H9S87_12335	COG1286	toxin biosynthetic process
H9S87_12340	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H9S87_12345	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9S87_12350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9S87_12350	COG0072	phenylalanine-tRNA ligase activity
H9S87_12355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9S87_12360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9S87_12370	COG1966	Carbon starvation protein
H9S87_12375	COG1363	Peptidase, m42
H9S87_12385	COG3326	Membrane
H9S87_12390	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H9S87_12395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9S87_12400	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9S87_12405	COG1346	cytolysis
H9S87_12415	COG3279	Response regulator of the LytR AlgR family
H9S87_12420	COG3275	phosphorelay sensor kinase activity
H9S87_12425	COG1011	Hydrolase
H9S87_12430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9S87_12440	COG0398	Pfam SNARE associated Golgi protein
H9S87_12445	COG1484	DNA-dependent DNA replication
H9S87_12450	COG3611	Membrane attachment protein
H9S87_12455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9S87_12465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H9S87_12470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9S87_12475	COG0237	dephospho-CoA kinase activity
H9S87_12480	COG1971	Probably functions as a manganese efflux pump
H9S87_12485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9S87_12490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9S87_12490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9S87_12495	COG5002	protein histidine kinase activity
H9S87_12500	COG0745	RESPONSE REGULATOR receiver
H9S87_12505	COG0039	L-malate dehydrogenase activity
H9S87_12510	COG0538	isocitrate dehydrogenase activity
H9S87_12515	COG0372	Belongs to the citrate synthase family
H9S87_12520	COG2707	UPF0756 membrane protein
H9S87_12525	COG0628	permease
H9S87_12530	COG3030	protein affecting phage T7 exclusion by the F plasmid
H9S87_12540	COG0205	6-phosphofructokinase activity
H9S87_12545	COG0825	malonyl-CoA metabolic process
H9S87_12550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9S87_12555	COG0281	malic enzyme
H9S87_12560	COG0587	DNA-directed DNA polymerase activity
H9S87_12580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9S87_12590	COG4109	DRTGG domain
H9S87_12595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H9S87_12600	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_12605	COG0165	Argininosuccinate lyase
H9S87_12610	COG0137	argininosuccinate synthase activity
H9S87_12615	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9S87_12620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9S87_12625	COG0827	DNA restriction-modification system
H9S87_12630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H9S87_12635	COG3874	Sporulation protein YtfJ
H9S87_12645	COG1714	RDD family
H9S87_12650	COG0616	signal peptide processing
H9S87_12655	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9S87_12665	COG3239	Fatty acid desaturase
H9S87_12670	COG4585	Histidine kinase
H9S87_12675	COG2197	response regulator
H9S87_12680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_12685	COG0745	RESPONSE REGULATOR receiver
H9S87_12690	COG2205	protein histidine kinase activity
H9S87_12695	COG1136	(ABC) transporter
H9S87_12700	COG0577	efflux transmembrane transporter activity
H9S87_12705	COG0402	S-adenosylhomocysteine deaminase activity
H9S87_12710	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9S87_12740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9S87_12750	COG0301	tRNA thio-modification
H9S87_12755	COG1104	cysteine desulfurase activity
H9S87_12760	COG1114	Component of the transport system for branched-chain amino acids
H9S87_12765	COG1114	Component of the transport system for branched-chain amino acids
H9S87_12770	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H9S87_12775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9S87_12780	COG1309	transcriptional regulator
H9S87_12785	COG1956	GAF domain-containing protein
H9S87_12790	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9S87_12800	COG1335	isochorismatase
H9S87_12810	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H9S87_12815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9S87_12820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9S87_12825	COG0454	-acetyltransferase
H9S87_12830	COG0517	IMP dehydrogenase activity
H9S87_12835	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9S87_12840	COG1609	Transcriptional regulator
H9S87_12845	COG1605	Chorismate mutase
H9S87_12845	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H9S87_12850	COG3118	belongs to the thioredoxin family
H9S87_12855	COG4980	gas vesicle protein
H9S87_12860	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H9S87_12865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9S87_12870	COG1674	ftsk spoiiie
H9S87_12875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9S87_12880	COG4848	Belongs to the UPF0354 family
H9S87_12885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_12900	COG1363	Peptidase, m42
H9S87_12905	COG5584	Small secreted protein
H9S87_12910	COG0281	malic enzyme
H9S87_12915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9S87_12920	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9S87_12930	COG0510	thiamine kinase activity
H9S87_12935	COG1597	lipid kinase activity
H9S87_12945	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H9S87_12950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9S87_12955	COG3340	Belongs to the peptidase S51 family
H9S87_12960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9S87_12965	COG2252	PERMEase
H9S87_12970	COG1349	DNA-binding transcription factor activity
H9S87_12975	COG1187	pseudouridine synthase activity
H9S87_12980	COG2244	polysaccharide biosynthetic process
H9S87_12985	COG2081	HI0933 family
H9S87_12995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9S87_13000	COG3196	Protein conserved in bacteria
H9S87_13010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9S87_13015	COG5578	integral membrane protein
H9S87_13020	COG0673	inositol 2-dehydrogenase activity
H9S87_13025	COG1653	transport
H9S87_13030	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H9S87_13035	COG4209	transmembrane transport
H9S87_13040	COG2207	Transcriptional regulator
H9S87_13045	COG1733	regulation of RNA biosynthetic process
H9S87_13050	COG2814	Major facilitator Superfamily
H9S87_13055	COG0656	L-ascorbic acid biosynthetic process
H9S87_13060	COG1653	transport
H9S87_13065	COG0395	ABC-type sugar transport system, permease component
H9S87_13070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9S87_13075	COG1073	alpha beta
H9S87_13080	COG0495	leucyl-tRNA aminoacylation
H9S87_13090	COG2202	Pas domain
H9S87_13090	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_13095	COG2433	Pfam Transposase IS66
H9S87_13100	COG0577	efflux transmembrane transporter activity
H9S87_13105	COG1136	(ABC) transporter
H9S87_13115	COG1131	(ABC) transporter
H9S87_13120	COG1725	Transcriptional regulator
H9S87_13135	COG1242	4 iron, 4 sulfur cluster binding
H9S87_13140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H9S87_13150	COG2267	carboxylic ester hydrolase activity
H9S87_13155	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9S87_13160	COG0367	asparagine synthase
H9S87_13165	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9S87_13170	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H9S87_13180	COG1506	peptidase
H9S87_13185	COG1233	COG1233 Phytoene dehydrogenase and related
H9S87_13205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9S87_13210	COG1116	anion transmembrane transporter activity
H9S87_13215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9S87_13220	COG0494	nUDIX hydrolase
H9S87_13225	COG2310	stress, protein
H9S87_13240	COG4824	toxin secretion phage lysis holin
H9S87_13250	COG0783	Belongs to the Dps family
H9S87_13265	COG1854	S-ribosylhomocysteine lyase activity
H9S87_13270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H9S87_13275	COG0288	reversible hydration of carbon dioxide
H9S87_13280	COG3443	Belongs to the bacterial solute-binding protein 9 family
H9S87_13280	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9S87_13285	COG0254	rRNA binding
H9S87_13290	COG1271	oxidase subunit
H9S87_13295	COG1294	oxidase, subunit
H9S87_13310	COG4948	Mandelate Racemase Muconate Lactonizing
H9S87_13315	COG0318	PFAM AMP-dependent synthetase and ligase
H9S87_13320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H9S87_13325	COG0596	Alpha beta hydrolase
H9S87_13330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H9S87_13335	COG1169	isochorismate synthase
H9S87_13340	COG1575	Belongs to the MenA family. Type 1 subfamily
H9S87_13350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9S87_13480	COG3859	Proton-coupled thiamine transporter YuaJ
H9S87_13485	COG1247	-acetyltransferase
H9S87_13490	COG3339	Conserved Protein
H9S87_13495	COG0772	Belongs to the SEDS family
H9S87_13500	COG0772	Belongs to the SEDS family
H9S87_13505	COG2268	Band 7 protein
H9S87_13510	COG1585	Membrane protein implicated in regulation of membrane protease activity
H9S87_13515	COG2318	DinB family
H9S87_13520	COG1454	alcohol dehydrogenase
H9S87_13525	COG1012	belongs to the aldehyde dehydrogenase family
H9S87_13530	COG1510	regulation of RNA biosynthetic process
H9S87_13540	COG0457	Tetratricopeptide repeat
H9S87_13550	COG3409	Peptidoglycan-binding domain 1 protein
H9S87_13550	COG5632	N-Acetylmuramoyl-L-alanine amidase
H9S87_13565	COG3594	Acyltransferase
H9S87_13590	COG3778	Protein conserved in bacteria
H9S87_13595	COG3299	homolog of phage Mu protein gp47
H9S87_13600	COG3628	GPW Gp25 family protein
H9S87_13610	COG4193	domain, Protein
H9S87_13615	COG1652	LysM domain
H9S87_13620	COG3953	SLT domain
H9S87_13620	COG5280	Phage tail tape measure protein TP901
H9S87_13620	COG3953	SLT domain
H9S87_13620	COG5280	Phage tail tape measure protein TP901
H9S87_13680	COG4653	Phage capsid family
H9S87_13685	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H9S87_13695	COG2369	cell adhesion
H9S87_13700	COG5518	Phage portal protein
H9S87_13705	COG1783	phage Terminase large subunit
H9S87_13740	COG5444	nuclease activity
H9S87_13780	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H9S87_13795	COG0305	Participates in initiation and elongation during chromosome replication
H9S87_13860	COG1476	TRANSCRIPTIONal
H9S87_13865	COG3620	sequence-specific DNA binding
H9S87_13875	COG2856	Zn peptidase
H9S87_13880	COG0582	viral genome integration into host DNA
H9S87_13895	COG5632	N-Acetylmuramoyl-L-alanine amidase
H9S87_13895	COG3409	Peptidoglycan-binding domain 1 protein
H9S87_13925	COG3778	Protein conserved in bacteria
H9S87_13930	COG3299	homolog of phage Mu protein gp47
H9S87_13935	COG3628	GPW Gp25 family protein
H9S87_13945	COG4193	domain, Protein
H9S87_13950	COG1652	LysM domain
H9S87_13955	COG5280	Phage tail tape measure protein TP901
H9S87_13955	COG3953	SLT domain
H9S87_13955	COG3953	SLT domain
H9S87_13955	COG5280	Phage tail tape measure protein TP901
H9S87_14010	COG4653	Phage capsid family
H9S87_14015	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H9S87_14020	COG5518	Phage portal protein
H9S87_14025	COG1783	phage Terminase large subunit
H9S87_14030	COG5484	DNA packaging
H9S87_14035	COG1595	DNA-templated transcription, initiation
H9S87_14045	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H9S87_14065	COG1396	sequence-specific DNA binding
H9S87_14075	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9S87_14085	COG1968	undecaprenyl-diphosphatase activity
H9S87_14090	COG0628	permease
H9S87_14100	COG0673	inositol 2-dehydrogenase activity
H9S87_14105	COG0693	protein deglycase activity
H9S87_14110	COG0840	transmembrane signaling receptor activity
H9S87_14115	COG0840	transmembrane signaling receptor activity
H9S87_14120	COG0840	transmembrane signaling receptor activity
H9S87_14125	COG0840	transmembrane signaling receptor activity
H9S87_14140	COG2070	2-Nitropropane dioxygenase
H9S87_14145	COG0432	Pfam Uncharacterised protein family UPF0047
H9S87_14150	COG1253	flavin adenine dinucleotide binding
H9S87_14155	COG2738	Putative neutral zinc metallopeptidase
H9S87_14165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9S87_14180	COG0166	Belongs to the GPI family
H9S87_14185	COG1979	alcohol dehydrogenase
H9S87_14190	COG1979	alcohol dehydrogenase
H9S87_14195	COG2155	Conserved Protein
H9S87_14200	COG1098	S1 RNA binding domain
H9S87_14205	COG0436	Aminotransferase
H9S87_14210	COG1522	sequence-specific DNA binding
H9S87_14215	COG2267	carboxylic ester hydrolase activity
H9S87_14225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H9S87_14230	COG2205	protein histidine kinase activity
H9S87_14245	COG5018	Exonuclease
H9S87_14250	COG2814	Major facilitator Superfamily
H9S87_14255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9S87_14260	COG3011	Protein conserved in bacteria
H9S87_14270	COG3290	protein histidine kinase activity
H9S87_14275	COG4565	transcriptional regulatory protein
H9S87_14285	COG3845	ABC transporter
H9S87_14290	COG4603	Belongs to the binding-protein-dependent transport system permease family
H9S87_14295	COG1079	Belongs to the binding-protein-dependent transport system permease family
H9S87_14300	COG3493	citrate carrier protein
H9S87_14310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9S87_14310	COG2111	Na H antiporter
H9S87_14315	COG2111	Na H antiporter
H9S87_14320	COG1006	Multisubunit Na H antiporter MnhC subunit
H9S87_14325	COG0651	ATP synthesis coupled electron transport
H9S87_14330	COG1863	multisubunit Na H antiporter MnhE subunit
H9S87_14335	COG2212	antiporter activity
H9S87_14340	COG1320	monovalent cation:proton antiporter activity
H9S87_14345	COG2050	protein possibly involved in aromatic compounds catabolism
H9S87_14350	COG2197	response regulator
H9S87_14355	COG4585	Histidine kinase
H9S87_14365	COG0142	geranyltranstransferase activity
H9S87_14380	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H9S87_14385	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9S87_14390	COG1335	isochorismatase
H9S87_14395	COG5506	Protein of unknown function (DUF1694)
H9S87_14415	COG0628	permease
H9S87_14430	COG1418	mRNA catabolic process
H9S87_14435	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_14445	COG1511	domain protein
H9S87_14450	COG0433	COG0433 Predicted ATPase
H9S87_14450	COG1674	ftsk spoiiie
H9S87_14455	COG4499	WXG100 protein secretion system (Wss), protein YukC
H9S87_14460	COG5417	Belongs to the EsaB family
H9S87_14465	COG4842	Belongs to the WXG100 family
H9S87_14470	COG2508	Transcriptional regulator
H9S87_14470	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H9S87_14475	COG0686	Belongs to the AlaDH PNT family
H9S87_14480	COG1268	BioY protein
H9S87_14485	COG4326	sporulation control protein
H9S87_14490	COG2056	Na+-H+ antiporter family
H9S87_14495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9S87_14500	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H9S87_14505	COG3584	3D domain protein
H9S87_14520	COG1252	NADH dehydrogenase
H9S87_14525	COG0492	ferredoxin-NADP+ reductase activity
H9S87_14540	COG0316	Belongs to the HesB IscA family
H9S87_14545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9S87_14550	COG4844	belongs to the
H9S87_14555	COG1252	NADH dehydrogenase
H9S87_14565	COG4837	Protein of unknown function (DUF1462)
H9S87_14570	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9S87_14575	COG0823	Involved in the tonB-independent uptake of proteins
H9S87_14575	COG1506	peptidase
H9S87_14575	COG4946	Tricorn protease homolog
H9S87_14580	COG0083	homoserine kinase activity
H9S87_14585	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9S87_14590	COG0460	homoserine dehydrogenase
H9S87_14595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9S87_14600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9S87_14605	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9S87_14610	COG0647	UMP catabolic process
H9S87_14615	COG2445	Protein of unknown function DUF86
H9S87_14620	COG4470	Protein conserved in bacteria
H9S87_14630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9S87_14635	COG0739	heme binding
H9S87_14645	COG3377	Domain of unknown function (DUF1805)
H9S87_14650	COG0737	Belongs to the 5'-nucleotidase family
H9S87_14655	COG1801	Protein of unknown function DUF72
H9S87_14660	COG2508	Transcriptional regulator
H9S87_14670	COG2814	Major facilitator Superfamily
H9S87_14675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9S87_14680	COG2356	endonuclease I
H9S87_14690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_14695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_14700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_14710	COG0642	Histidine kinase
H9S87_14710	COG5002	protein histidine kinase activity
H9S87_14715	COG0745	RESPONSE REGULATOR receiver
H9S87_14720	COG2311	Membrane
H9S87_14730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9S87_14745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H9S87_14755	COG0719	Fe-S assembly protein
H9S87_14760	COG0822	iron-sulfur transferase activity
H9S87_14765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9S87_14770	COG0719	Fe-S assembly protein
H9S87_14775	COG0396	ATPase activity
H9S87_14785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9S87_14790	COG1464	Belongs to the NlpA lipoprotein family
H9S87_14795	COG2011	ABC-type metal ion transport system permease component
H9S87_14800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9S87_14810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9S87_14815	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H9S87_14825	COG0509	glycine decarboxylation via glycine cleavage system
H9S87_14830	COG1393	Belongs to the ArsC family
H9S87_14835	COG1960	acyl-CoA dehydrogenase activity
H9S87_14840	COG0183	Belongs to the thiolase family
H9S87_14845	COG1024	Enoyl-CoA hydratase
H9S87_14845	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9S87_14860	COG5577	PFAM Coat F domain
H9S87_14870	COG1120	ATPase activity
H9S87_14880	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_14885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9S87_14890	COG0745	RESPONSE REGULATOR receiver
H9S87_14895	COG2770	Histidine kinase
H9S87_14895	COG2205	protein histidine kinase activity
H9S87_14905	COG1309	transcriptional regulator
H9S87_14910	COG0114	fumarate hydratase activity
H9S87_14920	COG0697	spore germination
H9S87_14925	COG0814	amino acid
H9S87_14940	COG2197	response regulator
H9S87_14945	COG4585	Histidine kinase
H9S87_14950	COG4758	membrane
H9S87_14960	COG1842	Phage shock protein A
H9S87_14965	COG4758	membrane
H9S87_14970	COG2096	Adenosyltransferase
H9S87_14975	COG1120	ATPase activity
H9S87_14980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_14985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_14995	COG2721	sulfolactate sulfo-lyase activity
H9S87_15000	COG0246	Mannitol dehydrogenase
H9S87_15005	COG1609	Transcriptional regulator
H9S87_15010	COG1904	glucuronate isomerase
H9S87_15015	COG2205	protein histidine kinase activity
H9S87_15020	COG0745	RESPONSE REGULATOR receiver
H9S87_15025	COG1120	ATPase activity
H9S87_15030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_15035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_15040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_15045	COG0531	amino acid
H9S87_15060	COG1988	membrane-bound metal-dependent
H9S87_15065	COG1368	sulfuric ester hydrolase activity
H9S87_15070	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9S87_15075	COG4149	molybdate abc transporter
H9S87_15095	COG0656	L-ascorbic acid biosynthetic process
H9S87_15100	COG1940	carbohydrate kinase activity
H9S87_15105	COG0025	NhaP-type Na H and K H
H9S87_15110	COG2860	membrane
H9S87_15115	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H9S87_15120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9S87_15125	COG2217	Heavy metal translocating P-type atpase
H9S87_15130	COG1121	(ABC) transporter
H9S87_15135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9S87_15140	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9S87_15150	COG3226	Transcriptional regulator
H9S87_15155	COG0784	Response regulator, receiver
H9S87_15160	COG4191	Histidine kinase
H9S87_15165	COG1027	Aspartate ammonia-lyase
H9S87_15180	COG2217	Heavy metal translocating P-type atpase
H9S87_15185	COG2608	mercury ion transmembrane transporter activity
H9S87_15190	COG1937	Protein conserved in bacteria
H9S87_15205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9S87_15220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9S87_15225	COG0557	exoribonuclease II activity
H9S87_15230	COG1647	Serine aminopeptidase, S33
H9S87_15235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9S87_15240	COG2002	toxin-antitoxin pair type II binding
H9S87_15245	COG1476	TRANSCRIPTIONal
H9S87_15250	COG1396	sequence-specific DNA binding
H9S87_15255	COG1396	sequence-specific DNA binding
H9S87_15260	COG1733	regulation of RNA biosynthetic process
H9S87_15265	COG1174	glycine betaine transport
H9S87_15270	COG1732	Glycine betaine
H9S87_15275	COG1174	glycine betaine transport
H9S87_15280	COG1125	glycine betaine transport
H9S87_15280	COG0517	IMP dehydrogenase activity
H9S87_15285	COG1510	regulation of RNA biosynthetic process
H9S87_15290	COG2095	MarC family integral membrane protein
H9S87_15300	COG0456	acetyltransferase
H9S87_15320	COG1131	(ABC) transporter
H9S87_15330	COG0148	phosphopyruvate hydratase activity
H9S87_15335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9S87_15340	COG0149	triose-phosphate isomerase activity
H9S87_15345	COG0126	phosphoglycerate kinase activity
H9S87_15350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9S87_15355	COG2390	Transcriptional regulator
H9S87_15360	COG0833	amino acid
H9S87_15365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9S87_15370	COG3829	transcription factor binding
H9S87_15375	COG2186	Transcriptional regulator
H9S87_15380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H9S87_15390	COG0534	Mate efflux family protein
H9S87_15395	COG4608	Belongs to the ABC transporter superfamily
H9S87_15400	COG0444	Belongs to the ABC transporter superfamily
H9S87_15405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9S87_15410	COG0601	transmembrane transport
H9S87_15415	COG0747	negative chemotaxis
H9S87_15420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9S87_15425	COG0110	maltose O-acetyltransferase activity
H9S87_15430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9S87_15435	COG2244	polysaccharide biosynthetic process
H9S87_15440	COG5039	Polysaccharide pyruvyl transferase
H9S87_15445	COG1216	Glycosyl transferase, family 2
H9S87_15455	COG0438	transferase activity, transferring glycosyl groups
H9S87_15460	COG1215	transferase activity, transferring glycosyl groups
H9S87_15465	COG0438	transferase activity, transferring glycosyl groups
H9S87_15470	COG1086	Polysaccharide biosynthesis protein
H9S87_15475	COG0489	protein tyrosine kinase activity
H9S87_15480	COG3944	biosynthesis protein
H9S87_15485	COG1396	sequence-specific DNA binding
H9S87_15495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_15500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_15505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9S87_15510	COG0726	polysaccharide deacetylase
H9S87_15515	COG0488	(ABC) transporter
H9S87_15520	COG1124	(ABC) transporter
H9S87_15535	COG0601	transmembrane transport
H9S87_15540	COG0747	negative chemotaxis
H9S87_15545	COG1819	glycosyl
H9S87_15550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_15560	COG0740	serine-type endopeptidase activity
H9S87_15565	COG1611	Belongs to the LOG family
H9S87_15570	COG1694	Mazg nucleotide pyrophosphohydrolase
H9S87_15575	COG0659	secondary active sulfate transmembrane transporter activity
H9S87_15580	COG0288	reversible hydration of carbon dioxide
H9S87_15585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9S87_15595	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H9S87_15600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_15605	COG1481	regulation of sporulation
H9S87_15610	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H9S87_15615	COG1660	Displays ATPase and GTPase activities
H9S87_15620	COG1051	belongs to the nudix hydrolase family
H9S87_15625	COG0492	ferredoxin-NADP+ reductase activity
H9S87_15630	COG0791	NLP P60 protein
H9S87_15630	COG3883	PFAM NLP P60 protein
H9S87_15635	COG0457	Tetratricopeptide repeat
H9S87_15640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9S87_15640	COG0140	phosphoribosyl-ATP diphosphatase activity
H9S87_15645	COG0107	imidazoleglycerol-phosphate synthase activity
H9S87_15650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9S87_15655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9S87_15660	COG0131	Imidazoleglycerol-phosphate dehydratase
H9S87_15665	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9S87_15670	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9S87_15675	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H9S87_15680	COG4990	cell redox homeostasis
H9S87_15685	COG2910	NAD(P)H-binding
H9S87_15690	COG1959	2 iron, 2 sulfur cluster binding
H9S87_15695	COG0110	maltose O-acetyltransferase activity
H9S87_15700	COG0546	phosphoglycolate phosphatase activity
H9S87_15705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H9S87_15715	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H9S87_15720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9S87_15725	COG0363	glucosamine-6-phosphate deaminase activity
H9S87_15730	COG2188	Transcriptional regulator
H9S87_15735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H9S87_15740	COG1950	PFAM Membrane protein of
H9S87_15745	COG1983	PspC domain protein
H9S87_15750	COG3595	metallopeptidase activity
H9S87_15765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9S87_15775	COG4897	Protein conserved in bacteria
H9S87_15780	COG0574	Belongs to the PEP-utilizing enzyme family
H9S87_15780	COG3848	Pyruvate phosphate dikinase
H9S87_15785	COG1309	transcriptional regulator
H9S87_15790	COG2814	Major facilitator Superfamily
H9S87_15800	COG0745	RESPONSE REGULATOR receiver
H9S87_15805	COG5002	protein histidine kinase activity
H9S87_15810	COG1113	amino acid transport
H9S87_15815	COG0778	Nitroreductase
H9S87_15820	COG1733	regulation of RNA biosynthetic process
H9S87_15825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9S87_15835	COG3409	Peptidoglycan-binding domain 1 protein
H9S87_15835	COG0793	Belongs to the peptidase S41A family
H9S87_15840	COG0730	response to heat
H9S87_15845	COG0791	NLP P60 protein
H9S87_15845	COG3883	PFAM NLP P60 protein
H9S87_15850	COG2177	Part of the ABC transporter FtsEX involved in
H9S87_15855	COG2884	Cell division ATP-binding protein ftsE
H9S87_15860	COG2010	Cytochrome c
H9S87_15865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9S87_15885	COG0653	protein targeting
H9S87_15890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H9S87_15895	COG0840	transmembrane signaling receptor activity
H9S87_15910	COG1516	flagellar protein fliS
H9S87_15915	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H9S87_15920	COG1334	flagellar protein FlaG
H9S87_15925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H9S87_15930	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
H9S87_15940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9S87_15945	COG1256	bacterial-type flagellum assembly
H9S87_15945	COG4786	Flagellar basal body rod
H9S87_15950	COG3418	PFAM FlgN family protein
H9S87_15965	COG1040	competence protein
H9S87_15975	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H9S87_15980	COG1307	EDD domain protein, DegV family
H9S87_15985	COG2197	response regulator
H9S87_15990	COG4585	Histidine kinase
H9S87_15995	COG1739	Uncharacterized protein family UPF0029
H9S87_16000	COG1316	TRANSCRIPTIONal
H9S87_16005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9S87_16010	COG0438	transferase activity, transferring glycosyl groups
H9S87_16015	COG1215	transferase activity, transferring glycosyl groups
H9S87_16020	COG3206	protein involved in exopolysaccharide biosynthesis
H9S87_16025	COG3307	-O-antigen
H9S87_16030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9S87_16035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H9S87_16040	COG0297	glycogen (starch) synthase activity
H9S87_16040	COG0438	transferase activity, transferring glycosyl groups
H9S87_16045	COG2244	polysaccharide biosynthetic process
H9S87_16060	COG2247	cell wall binding repeat
H9S87_16060	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9S87_16065	COG2247	cell wall binding repeat
H9S87_16065	COG2385	sporulation resulting in formation of a cellular spore
H9S87_16075	COG1316	TRANSCRIPTIONal
H9S87_16085	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9S87_16090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9S87_16095	COG1134	teichoic acid transport
H9S87_16100	COG1682	transport, permease protein
H9S87_16105	COG0463	Glycosyl transferase, family 2
H9S87_16105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9S87_16110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9S87_16120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9S87_16125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H9S87_16130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9S87_16135	COG4193	domain, Protein
H9S87_16140	COG1482	cell wall glycoprotein biosynthetic process
H9S87_16145	COG0395	ABC-type sugar transport system, permease component
H9S87_16150	COG1175	transmembrane transport
H9S87_16155	COG1653	transport
H9S87_16160	COG2197	response regulator
H9S87_16165	COG2972	Histidine kinase
H9S87_16175	COG0454	-acetyltransferase
H9S87_16180	COG0800	Aldolase
H9S87_16185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9S87_16190	COG1609	Transcriptional regulator
H9S87_16195	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H9S87_16200	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_16205	COG0697	spore germination
H9S87_16210	COG0814	amino acid
H9S87_16225	COG2814	Major facilitator Superfamily
H9S87_16230	COG1316	TRANSCRIPTIONal
H9S87_16235	COG0561	phosphatase activity
H9S87_16240	COG0791	NLP P60 protein
H9S87_16250	COG2843	Capsule synthesis protein
H9S87_16260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9S87_16265	COG0697	spore germination
H9S87_16280	COG1609	Transcriptional regulator
H9S87_16285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9S87_16290	COG1869	D-ribose catabolic process
H9S87_16295	COG1129	ABC transporter
H9S87_16300	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9S87_16305	COG1879	ABC-type sugar transport system periplasmic component
H9S87_16310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H9S87_16315	COG0583	DNA-binding transcription factor activity
H9S87_16320	COG0028	Belongs to the TPP enzyme family
H9S87_16325	COG3527	Alpha-acetolactate decarboxylase
H9S87_16330	COG1522	sequence-specific DNA binding
H9S87_16335	COG2059	Chromate
H9S87_16340	COG2059	Chromate
H9S87_16345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H9S87_16355	COG4715	Zinc finger, swim domain protein
H9S87_16360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9S87_16365	COG1366	Belongs to the anti-sigma-factor antagonist family
H9S87_16365	COG2202	Pas domain
H9S87_16370	COG0561	phosphatase activity
H9S87_16385	COG1970	mechanosensitive ion channel activity
H9S87_16390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9S87_16395	COG0457	Tetratricopeptide repeat
H9S87_16400	COG4786	Flagellar basal body rod
H9S87_16405	COG4786	Flagellar basal body rod
H9S87_16410	COG1077	Cell shape determining protein MreB Mrl
H9S87_16415	COG1609	Transcriptional regulator
H9S87_16420	COG1846	Transcriptional regulator
H9S87_16425	COG2814	Major facilitator Superfamily
H9S87_16430	COG0671	phosphoesterase, PA-phosphatase related
H9S87_16435	COG0477	Major facilitator Superfamily
H9S87_16440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_16445	COG0765	amino acid transport
H9S87_16455	COG0004	ammonium transporteR
H9S87_16460	COG0347	Belongs to the P(II) protein family
H9S87_16465	COG0739	heme binding
H9S87_16470	COG1247	-acetyltransferase
H9S87_16505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9S87_16510	COG0523	cobalamin synthesis protein
H9S87_16515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9S87_16520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9S87_16525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9S87_16530	COG2223	nitrite transmembrane transporter activity
H9S87_16535	COG0243	molybdopterin cofactor binding
H9S87_16540	COG2304	oxidoreductase activity
H9S87_16545	COG2304	oxidoreductase activity
H9S87_16550	COG2385	sporulation resulting in formation of a cellular spore
H9S87_16555	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9S87_16565	COG4836	Membrane
H9S87_16575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9S87_16580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9S87_16585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9S87_16590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9S87_16595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9S87_16600	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9S87_16605	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9S87_16610	COG0356	it plays a direct role in the translocation of protons across the membrane
H9S87_16620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9S87_16625	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9S87_16630	COG4475	Protein of unknown function (DUF436)
H9S87_16635	COG0698	ribose 5-phosphate isomerase
H9S87_16640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9S87_16645	COG1971	Probably functions as a manganese efflux pump
H9S87_16650	COG0009	L-threonylcarbamoyladenylate synthase
H9S87_16655	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H9S87_16670	COG2890	protein-(glutamine-N5) methyltransferase activity
H9S87_16675	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9S87_16680	COG0789	Transcriptional regulator
H9S87_16685	COG0679	Auxin Efflux Carrier
H9S87_16690	COG0281	malic enzyme
H9S87_16695	COG1435	thymidine kinase activity
H9S87_16700	COG0254	rRNA binding
H9S87_16705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9S87_16710	COG1494	fructose-1,6-bisphosphatase
H9S87_16715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9S87_16720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9S87_16725	COG0191	fructose-bisphosphate aldolase activity
H9S87_16735	COG4821	SIS domain
H9S87_16740	COG0504	CTP synthase activity
H9S87_16745	COG3343	RNA polymerase activity
H9S87_16755	COG1960	acyl-CoA dehydrogenase activity
H9S87_16760	COG1960	acyl-CoA dehydrogenase activity
H9S87_16765	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9S87_16770	COG0183	Belongs to the thiolase family
H9S87_16775	COG0247	lactate metabolic process
H9S87_16775	COG2181	nitrate reductase activity
H9S87_16780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9S87_16785	COG4294	response to UV
H9S87_16795	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9S87_16800	COG1132	(ABC) transporter
H9S87_16805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9S87_16810	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9S87_16815	COG0018	arginyl-trna synthetase
H9S87_16820	COG4506	Protein conserved in bacteria
H9S87_16835	COG0010	Belongs to the arginase family
H9S87_16840	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H9S87_16845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9S87_16855	COG1994	Peptidase M50
H9S87_16860	COG1942	4-Oxalocrotonate Tautomerase
H9S87_16870	COG3465	dGTPase activity
H9S87_16875	COG1078	dGTPase activity
H9S87_16880	COG4844	belongs to the
H9S87_16940	COG0280	phosphate acetyltransferase
H9S87_16950	COG2814	Major facilitator Superfamily
H9S87_16955	COG1522	sequence-specific DNA binding
H9S87_16960	COG2814	Major facilitator Superfamily
H9S87_16965	COG0077	Prephenate dehydratase
H9S87_16970	COG1917	Cupin 2, conserved barrel domain protein
H9S87_16975	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_16980	COG0151	Belongs to the GarS family
H9S87_16985	COG0436	Aminotransferase
H9S87_16990	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_16995	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H9S87_17000	COG1091	dTDP-4-dehydrorhamnose reductase activity
H9S87_17005	COG1088	dTDP-glucose 4,6-dehydratase activity
H9S87_17010	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H9S87_17015	COG3980	spore coat polysaccharide biosynthesis protein
H9S87_17020	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H9S87_17025	COG2089	acid synthase
H9S87_17030	COG0456	acetyltransferase
H9S87_17035	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9S87_17040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H9S87_17045	COG0463	Glycosyl transferase, family 2
H9S87_17065	COG2363	Small membrane protein
H9S87_17070	COG2233	PERMEase
H9S87_17080	COG1012	belongs to the aldehyde dehydrogenase family
H9S87_17085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9S87_17090	COG1216	Glycosyl transferase, family 2
H9S87_17100	COG0351	phosphomethylpyrimidine kinase
H9S87_17125	COG0693	protein deglycase activity
H9S87_17165	COG1621	beta-fructofuranosidase activity
H9S87_17170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_17170	COG1263	PTS System
H9S87_17175	COG3711	transcriptional antiterminator
H9S87_17185	COG1404	Belongs to the peptidase S8 family
H9S87_17190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9S87_17195	COG0778	Nitroreductase
H9S87_17200	COG0772	Belongs to the SEDS family
H9S87_17210	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H9S87_17215	COG1845	cytochrome c oxidase, subunit III
H9S87_17220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9S87_17225	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9S87_17235	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H9S87_17240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9S87_17245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H9S87_17260	COG2246	polysaccharide biosynthetic process
H9S87_17280	COG3162	membrane
H9S87_17285	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9S87_17295	COG0352	thiamine-phosphate diphosphorylase activity
H9S87_17300	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H9S87_17305	COG0583	DNA-binding transcription factor activity
H9S87_17315	COG1346	cytolysis
H9S87_17320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9S87_17325	COG0346	lactoylglutathione lyase activity
H9S87_17335	COG0765	amino acid transport
H9S87_17340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9S87_17345	COG0457	Tetratricopeptide repeat
H9S87_17355	COG2357	RelA SpoT domain protein
H9S87_17360	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9S87_17365	COG1129	ABC transporter
H9S87_17375	COG3420	alginic acid biosynthetic process
H9S87_17380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9S87_17390	COG1486	melibiose metabolic process
H9S87_17395	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9S87_17400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9S87_17405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9S87_17410	COG3711	transcriptional antiterminator
H9S87_17410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_17425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9S87_17440	COG1595	DNA-templated transcription, initiation
H9S87_17450	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H9S87_17455	COG4988	ABC transporter
H9S87_17460	COG1294	oxidase, subunit
H9S87_17465	COG1271	oxidase subunit
H9S87_17485	COG4509	Sortase family
H9S87_17510	COG5386	Cell surface protein
H9S87_17515	COG5386	Cell surface protein
H9S87_17520	COG1733	regulation of RNA biosynthetic process
H9S87_17525	COG2514	catechol 2,3-dioxygenase activity
H9S87_17530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9S87_17530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9S87_17535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9S87_17535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9S87_17540	COG0346	lactoylglutathione lyase activity
H9S87_17545	COG0726	polysaccharide deacetylase
H9S87_17550	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9S87_17555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9S87_17560	COG2723	6-phospho-beta-galactosidase activity
H9S87_17565	COG1312	Catalyzes the dehydration of D-mannonate
H9S87_17570	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9S87_17575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9S87_17575	COG3711	transcriptional antiterminator
H9S87_17600	COG1757	Na H antiporter
H9S87_17605	COG1027	Aspartate ammonia-lyase
H9S87_17610	COG0252	asparaginase activity
H9S87_17615	COG1396	sequence-specific DNA binding
H9S87_17640	COG4842	Belongs to the WXG100 family
H9S87_17645	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9S87_17660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9S87_17665	COG2723	6-phospho-beta-galactosidase activity
H9S87_17670	COG2190	(PTS) system
H9S87_17670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_17670	COG1263	PTS System
H9S87_17675	COG3711	transcriptional antiterminator
H9S87_17680	COG3878	Protein conserved in bacteria
H9S87_17690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H9S87_17695	COG1122	ATPase activity
H9S87_17700	COG4721	ABC-type cobalt transport system, permease component
H9S87_17705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9S87_17740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H9S87_17745	COG0778	Nitroreductase
H9S87_17750	COG1846	Transcriptional regulator
H9S87_17755	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9S87_17760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9S87_17765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9S87_17770	COG2390	Transcriptional regulator
H9S87_17780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9S87_17780	COG2755	lipolytic protein G-D-S-L family
H9S87_17800	COG0561	phosphatase activity
H9S87_17805	COG0789	Transcriptional regulator
H9S87_17810	COG0673	inositol 2-dehydrogenase activity
H9S87_17815	COG0840	transmembrane signaling receptor activity
H9S87_17820	COG1113	amino acid transport
H9S87_17825	COG4335	DNA alkylation repair
H9S87_17835	COG1070	Carbohydrate kinase
H9S87_17840	COG1737	Transcriptional regulator
H9S87_17860	COG0583	DNA-binding transcription factor activity
H9S87_17865	COG1609	Transcriptional regulator
H9S87_17870	COG2182	Extracellular solute-binding protein
H9S87_17875	COG1175	transmembrane transport
H9S87_17880	COG3833	ABC-type maltose transport systems, permease component
H9S87_17890	COG1874	Beta-galactosidase
H9S87_17895	COG2851	Citrate transporter
H9S87_17905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H9S87_17910	COG1131	(ABC) transporter
H9S87_17915	COG2824	Alkylphosphonate utilization operon protein PhnA
H9S87_17920	COG1929	Belongs to the glycerate kinase type-1 family
H9S87_17925	COG2610	gluconate transmembrane transporter activity
H9S87_17930	COG3835	regulator
H9S87_17935	COG1309	transcriptional regulator
H9S87_17940	COG2814	Major facilitator Superfamily
H9S87_17950	COG1136	(ABC) transporter
H9S87_17955	COG0457	Tetratricopeptide repeat
H9S87_17960	COG3711	transcriptional antiterminator
H9S87_17965	COG2723	6-phospho-beta-galactosidase activity
H9S87_17970	COG1263	PTS System
H9S87_17970	COG2190	(PTS) system
H9S87_17970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9S87_18005	COG1113	amino acid transport
H9S87_18010	COG1609	Transcriptional regulator
H9S87_18015	COG2814	Major facilitator Superfamily
H9S87_18020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9S87_18025	COG2814	Major facilitator Superfamily
H9S87_18045	COG5444	nuclease activity
H9S87_18055	COG2723	6-phospho-beta-galactosidase activity
H9S87_18065	COG2188	Transcriptional regulator
H9S87_18090	COG1131	(ABC) transporter
H9S87_18095	COG1396	sequence-specific DNA binding
H9S87_18110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9S87_18115	COG2814	Major facilitator Superfamily
H9S87_18120	COG0640	Transcriptional regulator
H9S87_18155	COG1404	Belongs to the peptidase S8 family
H9S87_18175	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9S87_18185	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H9S87_18195	COG4720	Psort location CytoplasmicMembrane, score
H9S87_18215	COG0456	acetyltransferase
H9S87_18220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9S87_18225	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H9S87_18230	COG4853	Protein conserved in bacteria
H9S87_18235	COG4863	YycH protein
H9S87_18240	COG5002	protein histidine kinase activity
H9S87_18245	COG0745	RESPONSE REGULATOR receiver
H9S87_18270	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9S87_18280	COG2311	Membrane
H9S87_18285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9S87_18290	COG1309	transcriptional regulator
H9S87_18295	COG2124	cytochrome p450
H9S87_18300	COG0346	lactoylglutathione lyase activity
H9S87_18305	COG0305	Participates in initiation and elongation during chromosome replication
H9S87_18320	COG2819	hydrolase of the alpha beta superfamily
H9S87_18325	COG1028	Short-chain dehydrogenase reductase Sdr
H9S87_18330	COG1169	isochorismate synthase
H9S87_18335	COG1021	2,3-dihydroxybenzoate-AMP ligase
H9S87_18340	COG1535	isochorismatase
H9S87_18340	COG3433	isochorismatase activity
H9S87_18345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H9S87_18350	COG3251	PFAM MbtH domain protein
H9S87_18355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_18355	COG2207	Transcriptional regulator
H9S87_18360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9S87_18365	COG2819	hydrolase of the alpha beta superfamily
H9S87_18370	COG3093	addiction module antidote protein HigA
H9S87_18375	COG2807	transmembrane transport
H9S87_18380	COG0359	binds to the 23S rRNA
H9S87_18385	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H9S87_18390	COG4241	membrane
H9S87_18395	COG1227	inorganic diphosphatase activity
H9S87_18405	COG1595	DNA-templated transcription, initiation
H9S87_18415	COG0753	catalase activity
H9S87_18420	COG0655	NAD(P)H dehydrogenase (quinone) activity
H9S87_18425	COG0400	carboxylic ester hydrolase activity
H9S87_18430	COG0346	lactoylglutathione lyase activity
H9S87_18435	COG1174	glycine betaine transport
H9S87_18440	COG1125	glycine betaine transport
H9S87_18440	COG0517	IMP dehydrogenase activity
H9S87_18445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9S87_18450	COG0629	single-stranded DNA binding
H9S87_18455	COG0360	Binds together with S18 to 16S ribosomal RNA
H9S87_18460	COG0012	GTP binding
H9S87_18465	COG4481	Protein conserved in bacteria
H9S87_18480	COG3949	Membrane
H9S87_18490	COG1475	DNA binding
H9S87_18495	COG1192	Involved in chromosome partitioning
H9S87_18505	COG1475	DNA binding
H9S87_18510	COG0357	Ribosomal RNA small subunit methyltransferase G
H9S87_18515	COG0445	tRNA wobble uridine modification
H9S87_18520	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9S87_18525	COG1847	R3H domain protein
H9S87_18530	COG0706	membrane insertase activity
H9S87_18535	COG0594	ribonuclease P activity
H9S87_18540	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H9S87_18560	COG0791	NLP P60 protein
H9S87_18560	COG0741	lytic transglycosylase activity
H9S87_18670	COG0457	Tetratricopeptide repeat
H9S87_18800	COG2002	toxin-antitoxin pair type II binding
H9S87_18805	COG0457	Tetratricopeptide repeat
H9S87_18975	COG0629	single-stranded DNA binding
H9S87_19050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII