UP12_07020 ff3c1d0befb49c6cc893e54ff7db43ca 222 Pfam PF02254 TrkA-N domain 5 120 1.3E-28 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UP12_07020 ff3c1d0befb49c6cc893e54ff7db43ca 222 Pfam PF02080 TrkA-C domain 150 215 2.9E-15 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UP12_07020 ff3c1d0befb49c6cc893e54ff7db43ca 222 Gene3D G3DSA:3.30.70.1450 138 218 2.8E-27 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_07020 ff3c1d0befb49c6cc893e54ff7db43ca 222 SUPERFAMILY SSF51735 4 134 5.17E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_07020 ff3c1d0befb49c6cc893e54ff7db43ca 222 SUPERFAMILY SSF116726 131 215 6.93E-22 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_07020 ff3c1d0befb49c6cc893e54ff7db43ca 222 Gene3D G3DSA:3.40.50.720 1 137 9.5E-39 T 11-10-2018 UP12_06865 2ffc48f86f3bda9ac2c70ef5e15abd5c 141 SUPERFAMILY SSF52218 1 133 1.89E-36 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_06865 2ffc48f86f3bda9ac2c70ef5e15abd5c 141 Gene3D G3DSA:3.40.50.360 1 135 1.9E-34 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_06865 2ffc48f86f3bda9ac2c70ef5e15abd5c 141 TIGRFAM TIGR01753 flav_short: flavodoxin 1 133 3.0E-47 T 11-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 UP12_06865 2ffc48f86f3bda9ac2c70ef5e15abd5c 141 Pfam PF00258 Flavodoxin 1 124 4.1E-29 T 11-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 UP12_03645 1806085791acf0d5cdbb2346e5a68fd3 529 Gene3D G3DSA:3.30.1360.60 446 527 1.8E-20 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_03645 1806085791acf0d5cdbb2346e5a68fd3 529 Pfam PF00367 phosphotransferase system, EIIB 456 485 2.2E-14 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_03645 1806085791acf0d5cdbb2346e5a68fd3 529 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 464 481 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_03645 1806085791acf0d5cdbb2346e5a68fd3 529 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 1 524 4.8E-245 T 11-10-2018 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 UP12_03645 1806085791acf0d5cdbb2346e5a68fd3 529 Pfam PF02378 Phosphotransferase system, EIIC 9 343 1.3E-63 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_03645 1806085791acf0d5cdbb2346e5a68fd3 529 SUPERFAMILY SSF55604 452 525 1.19E-16 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 297 311 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 Gene3D G3DSA:2.70.20.10 212 455 2.7E-113 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 1.7E-24 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 188 206 1.7E-24 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 1.7E-24 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 488 502 1.7E-24 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 377 393 1.7E-24 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 SMART SM00493 1 125 6.3E-9 T 11-10-2018 IPR006171 TOPRIM domain UP12_19335 eefa9203994549783f0bb9f638b8d363 673 Gene3D G3DSA:3.40.50.140 1 154 1.0E-38 T 11-10-2018 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 SMART SM00437 260 525 1.5E-66 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 Pfam PF01751 Toprim domain 2 121 1.9E-11 T 11-10-2018 IPR006171 TOPRIM domain UP12_19335 eefa9203994549783f0bb9f638b8d363 673 Pfam PF01131 DNA topoisomerase 152 560 6.9E-98 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 SMART SM00436 126 218 1.4E-11 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 SUPERFAMILY SSF56712 1 577 2.88E-137 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain UP12_19335 eefa9203994549783f0bb9f638b8d363 673 Gene3D G3DSA:1.10.290.10 269 391 2.7E-113 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 UP12_19335 eefa9203994549783f0bb9f638b8d363 673 Gene3D G3DSA:1.10.460.10 162 570 2.7E-113 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 UP12_00665 9d96e5d9d37ead57fdbcc3e5baf5f3a4 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 11-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00665 9d96e5d9d37ead57fdbcc3e5baf5f3a4 166 Pfam PF00466 Ribosomal protein L10 6 101 9.8E-30 T 11-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 UP12_00665 9d96e5d9d37ead57fdbcc3e5baf5f3a4 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 29.405 T 11-10-2018 IPR022973 Ribosomal protein L10 UP12_00665 9d96e5d9d37ead57fdbcc3e5baf5f3a4 166 Gene3D G3DSA:3.30.70.1730 3 165 9.9E-43 T 11-10-2018 UP12_00665 9d96e5d9d37ead57fdbcc3e5baf5f3a4 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 5 144 0.003 T 11-10-2018 UP12_00665 9d96e5d9d37ead57fdbcc3e5baf5f3a4 166 SUPERFAMILY SSF160369 6 160 3.4E-55 T 11-10-2018 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 SUPERFAMILY SSF50677 202 393 3.77E-64 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 SUPERFAMILY SSF52374 1 640 3.49E-153 T 11-10-2018 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 833 0.0 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 2.3E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 2.3E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 2.3E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 2.3E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 2.3E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 20.486 T 11-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 Pfam PF08264 Anticodon-binding domain of tRNA 677 831 1.4E-30 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 Gene3D G3DSA:1.10.730.20 632 918 3.5E-90 T 11-10-2018 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 SUPERFAMILY SSF47323 644 917 7.29E-74 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 630 6.3E-221 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 Gene3D G3DSA:3.40.50.620 24 621 1.6E-262 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_07510 4af1d6867897f052e55ad6cc06aae5b8 921 Gene3D G3DSA:3.90.740.10 194 398 1.6E-262 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 Gene3D G3DSA:3.40.50.10490 58 226 2.2E-147 T 11-10-2018 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 26.721 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 11-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 6.3E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 6.3E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 6.3E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 6.3E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 6.3E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 6.3E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 11-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 Gene3D G3DSA:3.40.50.10490 227 417 2.2E-147 T 11-10-2018 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 Pfam PF00342 Phosphoglucose isomerase 76 296 8.2E-19 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 Pfam PF00342 Phosphoglucose isomerase 369 426 4.6E-5 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 SUPERFAMILY SSF53697 4 447 1.03E-142 T 11-10-2018 UP12_14790 6e5217d2b10c992d0f3c415ed6f281ca 451 Gene3D G3DSA:3.40.50.10490 1 57 1.5E-18 T 11-10-2018 UP12_08985 0819c448ed311463582a2972cd6be655 511 SUPERFAMILY SSF75005 41 383 5.85E-54 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UP12_08985 0819c448ed311463582a2972cd6be655 511 Pfam PF04616 Glycosyl hydrolases family 43 47 361 7.5E-30 T 11-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UP12_08985 0819c448ed311463582a2972cd6be655 511 Pfam PF03422 Carbohydrate binding module (family 6) 386 510 1.0E-33 T 11-10-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 UP12_08985 0819c448ed311463582a2972cd6be655 511 Gene3D G3DSA:2.115.10.20 33 375 2.5E-118 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UP12_08985 0819c448ed311463582a2972cd6be655 511 SMART SM00606 378 510 9.1E-51 T 11-10-2018 IPR006584 Cellulose binding, type IV GO:0030246 UP12_08985 0819c448ed311463582a2972cd6be655 511 SUPERFAMILY SSF49785 379 509 5.78E-27 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily UP12_08985 0819c448ed311463582a2972cd6be655 511 Gene3D G3DSA:2.60.120.260 376 511 2.7E-45 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily UP12_01815 4d869806a15c2ace7b96d2aac4c39d8f 239 Pfam PF01487 Type I 3-dehydroquinase 3 230 8.0E-64 T 11-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_01815 4d869806a15c2ace7b96d2aac4c39d8f 239 Gene3D G3DSA:3.20.20.70 1 236 4.5E-83 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_01815 4d869806a15c2ace7b96d2aac4c39d8f 239 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 1 229 1.2E-62 T 11-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_01815 4d869806a15c2ace7b96d2aac4c39d8f 239 SUPERFAMILY SSF51569 1 232 6.23E-66 T 11-10-2018 UP12_01815 4d869806a15c2ace7b96d2aac4c39d8f 239 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 1 233 32.732 T 11-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_07865 fdc718c27be1b8043c74ca3fa1dd196d 181 PIRSF PIRSF039093 1 181 3.8E-84 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 UP12_07865 fdc718c27be1b8043c74ca3fa1dd196d 181 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 40.612 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 UP12_07865 fdc718c27be1b8043c74ca3fa1dd196d 181 SUPERFAMILY SSF56235 4 180 6.11E-60 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_07865 fdc718c27be1b8043c74ca3fa1dd196d 181 Pfam PF00227 Proteasome subunit 5 178 1.0E-26 T 11-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 UP12_07865 fdc718c27be1b8043c74ca3fa1dd196d 181 Gene3D G3DSA:3.60.20.10 2 181 9.3E-68 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_07865 fdc718c27be1b8043c74ca3fa1dd196d 181 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 1.0E-81 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 UP12_16475 b81e03c91d8a48a5c696c3805577b565 111 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 40 107 1.6E-14 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_16475 b81e03c91d8a48a5c696c3805577b565 111 PIRSF PIRSF000025 1 111 6.1E-35 T 11-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 UP12_16475 b81e03c91d8a48a5c696c3805577b565 111 Gene3D G3DSA:1.10.760.10 42 111 9.7E-28 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UP12_16475 b81e03c91d8a48a5c696c3805577b565 111 SUPERFAMILY SSF46626 8 109 1.72E-18 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UP12_10660 ceb9b418c3403e601916bc93e7814602 108 SUPERFAMILY SSF89360 1 106 3.53E-24 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UP12_10660 ceb9b418c3403e601916bc93e7814602 108 Gene3D G3DSA:2.60.300.12 1 108 1.5E-7 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UP12_10660 ceb9b418c3403e601916bc93e7814602 108 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 105 8.5E-25 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 UP12_14895 462630e7d7b9d2810287d880c0817c68 511 SUPERFAMILY SSF52540 256 490 2.22E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_14895 462630e7d7b9d2810287d880c0817c68 511 Gene3D G3DSA:3.40.50.300 253 510 7.8E-41 T 11-10-2018 UP12_14895 462630e7d7b9d2810287d880c0817c68 511 SUPERFAMILY SSF52540 3 227 1.3E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_14895 462630e7d7b9d2810287d880c0817c68 511 Gene3D G3DSA:3.40.50.300 2 237 4.4E-56 T 11-10-2018 UP12_14895 462630e7d7b9d2810287d880c0817c68 511 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_14895 462630e7d7b9d2810287d880c0817c68 511 SMART SM00382 29 225 7.0E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_14895 462630e7d7b9d2810287d880c0817c68 511 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_14895 462630e7d7b9d2810287d880c0817c68 511 Pfam PF00005 ABC transporter 21 169 4.1E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_14895 462630e7d7b9d2810287d880c0817c68 511 Pfam PF00005 ABC transporter 274 429 1.7E-18 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_10980 7efab7716f247700ef846100f9c50d25 448 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 441 30.051 T 11-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 UP12_10980 7efab7716f247700ef846100f9c50d25 448 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 356 4.6E-137 T 11-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 UP12_10980 7efab7716f247700ef846100f9c50d25 448 Pfam PF02601 Exonuclease VII, large subunit 125 438 3.2E-99 T 11-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 UP12_10980 7efab7716f247700ef846100f9c50d25 448 Pfam PF13742 OB-fold nucleic acid binding domain 8 102 3.3E-30 T 11-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 UP12_10025 9000a8c84bc3f5ed4c60b569b73991a5 234 Gene3D G3DSA:1.10.10.10 1 115 3.2E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10025 9000a8c84bc3f5ed4c60b569b73991a5 234 Pfam PF07261 Replication initiation and membrane attachment 131 202 4.8E-25 T 11-10-2018 IPR006343 DnaD domain UP12_10025 9000a8c84bc3f5ed4c60b569b73991a5 234 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 129 201 1.2E-23 T 11-10-2018 IPR006343 DnaD domain UP12_10025 9000a8c84bc3f5ed4c60b569b73991a5 234 SUPERFAMILY SSF158499 130 195 8.11E-20 T 11-10-2018 IPR034829 DnaD-like domain superfamily UP12_10025 9000a8c84bc3f5ed4c60b569b73991a5 234 SUPERFAMILY SSF46785 23 88 3.29E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_10025 9000a8c84bc3f5ed4c60b569b73991a5 234 Gene3D G3DSA:1.10.10.630 125 201 1.9E-30 T 11-10-2018 IPR034829 DnaD-like domain superfamily UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 Pfam PF01476 LysM domain 165 207 2.0E-17 T 11-10-2018 IPR018392 LysM domain UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 SUPERFAMILY SSF47090 226 294 2.41E-15 T 11-10-2018 IPR036365 PGBD-like superfamily UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 SUPERFAMILY SSF55846 1 154 6.48E-48 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 Pfam PF01471 Putative peptidoglycan binding domain 232 293 5.8E-15 T 11-10-2018 IPR002477 Peptidoglycan binding-like UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 Gene3D G3DSA:1.10.101.10 222 296 3.1E-16 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 23 140 4.7E-24 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 Gene3D G3DSA:3.40.80.10 1 153 2.5E-54 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 Gene3D G3DSA:3.10.350.10 154 215 1.6E-20 T 11-10-2018 IPR036779 LysM domain superfamily UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 SMART SM00644 11 153 1.3E-32 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 SUPERFAMILY SSF54106 163 208 1.31E-13 T 11-10-2018 UP12_06155 bab015f5fdd134b953498cc9dcfafecd 299 SMART SM00257 164 208 5.7E-18 T 11-10-2018 IPR018392 LysM domain UP12_17785 695c4a42802759023d6c9c0853a932ad 249 Pfam PF00881 Nitroreductase family 8 165 1.8E-19 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UP12_17785 695c4a42802759023d6c9c0853a932ad 249 SUPERFAMILY SSF55469 2 248 4.19E-68 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_17785 695c4a42802759023d6c9c0853a932ad 249 PIRSF PIRSF005426 1 249 5.0E-91 T 11-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 UP12_17785 695c4a42802759023d6c9c0853a932ad 249 Gene3D G3DSA:3.40.109.10 1 249 4.2E-73 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_17355 ad65df5b00b08822035a81fb082092ef 204 Pfam PF00005 ABC transporter 18 145 7.8E-13 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17355 ad65df5b00b08822035a81fb082092ef 204 SUPERFAMILY SSF52540 9 196 4.02E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17355 ad65df5b00b08822035a81fb082092ef 204 SMART SM00382 26 203 8.0E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17355 ad65df5b00b08822035a81fb082092ef 204 Gene3D G3DSA:3.40.50.300 1 202 6.5E-30 T 11-10-2018 UP12_16680 4cc987df41057626b300c509e5455803 702 Pfam PF04122 Putative cell wall binding repeat 2 64 149 3.6E-12 T 11-10-2018 IPR007253 Putative cell wall binding repeat 2 UP12_16680 4cc987df41057626b300c509e5455803 702 Pfam PF04122 Putative cell wall binding repeat 2 162 241 1.2E-10 T 11-10-2018 IPR007253 Putative cell wall binding repeat 2 UP12_16680 4cc987df41057626b300c509e5455803 702 Pfam PF04122 Putative cell wall binding repeat 2 252 337 2.2E-7 T 11-10-2018 IPR007253 Putative cell wall binding repeat 2 UP12_16680 4cc987df41057626b300c509e5455803 702 Pfam PF08486 Stage II sporulation protein 412 488 3.8E-23 T 11-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal UP12_16680 4cc987df41057626b300c509e5455803 702 Gene3D G3DSA:3.40.50.12090 87 180 3.8E-5 T 11-10-2018 UP12_16680 4cc987df41057626b300c509e5455803 702 Gene3D G3DSA:3.40.50.12090 182 271 2.1E-5 T 11-10-2018 UP12_16680 4cc987df41057626b300c509e5455803 702 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 411 700 1.5E-77 T 11-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 SUPERFAMILY SSF56059 670 925 2.47E-77 T 11-10-2018 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 SUPERFAMILY SSF52440 1 127 3.17E-47 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 SUPERFAMILY SSF52440 555 672 7.63E-45 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 706 720 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1016 12.239 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 SUPERFAMILY SSF56059 128 399 5.3E-107 T 11-10-2018 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 SUPERFAMILY SSF48108 394 546 8.24E-43 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Gene3D G3DSA:3.40.50.20 550 659 1.5E-43 T 11-10-2018 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 542 6.4E-39 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.8E-61 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.8E-61 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.8E-61 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.8E-61 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 2.8E-61 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.8E-61 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 2.8E-61 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 953 0.0 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Gene3D G3DSA:3.30.1490.20 683 750 2.5E-82 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 7.0E-80 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 670 869 2.2E-34 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Gene3D G3DSA:3.30.470.20 664 922 2.5E-82 T 11-10-2018 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Gene3D G3DSA:1.10.1030.10 404 547 1.4E-40 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Gene3D G3DSA:3.40.50.20 1 116 6.0E-47 T 11-10-2018 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 832 839 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 Gene3D G3DSA:3.30.470.20 119 401 3.1E-122 T 11-10-2018 UP12_05590 bcea99a94b0613b7f34aa9e510feef6a 1026 SMART SM01096 420 542 1.6E-55 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 3.4E-29 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 3.4E-29 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 3.4E-29 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 3.4E-29 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 Pfam PF02154 Flagellar motor switch protein FliM 40 230 4.0E-80 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 PIRSF PIRSF002888 2 332 1.6E-121 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 322 1.6E-21 T 11-10-2018 IPR001543 Surface presentation of antigen (SpoA) UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 SUPERFAMILY SSF103039 47 232 5.84E-33 T 11-10-2018 IPR028976 CheC-like superfamily UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 Gene3D G3DSA:2.30.330.10 240 326 1.2E-10 T 11-10-2018 IPR036429 SpoA-like superfamily UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 322 2.0E-113 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 SUPERFAMILY SSF101801 251 323 8.76E-18 T 11-10-2018 IPR036429 SpoA-like superfamily UP12_07950 f975b726109a0cf9a80fc278aabcc698 332 Gene3D G3DSA:3.40.1550.10 46 231 8.1E-61 T 11-10-2018 IPR028976 CheC-like superfamily UP12_04395 2195d05bb3834dac5f6b892e04c667c4 340 Pfam PF00005 ABC transporter 28 183 1.2E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04395 2195d05bb3834dac5f6b892e04c667c4 340 SUPERFAMILY SSF52540 7 254 1.14E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04395 2195d05bb3834dac5f6b892e04c667c4 340 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_04395 2195d05bb3834dac5f6b892e04c667c4 340 SMART SM00382 36 241 4.5E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04395 2195d05bb3834dac5f6b892e04c667c4 340 Gene3D G3DSA:3.40.50.300 5 331 1.4E-104 T 11-10-2018 UP12_04395 2195d05bb3834dac5f6b892e04c667c4 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 1.1E-29 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_04395 2195d05bb3834dac5f6b892e04c667c4 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 3.9E-20 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 Pfam PF00295 Glycosyl hydrolases family 28 214 435 4.4E-27 T 11-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 Gene3D G3DSA:2.160.20.10 30 463 2.0E-140 T 11-10-2018 IPR012334 Pectin lyase fold UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 SMART SM00710 303 324 3.8 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 SMART SM00710 269 290 0.56 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 SMART SM00710 244 268 1100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 SMART SM00710 356 385 1400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 SMART SM00710 397 418 1700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 ProSitePatterns PS00502 Polygalacturonase active site. 310 324 - T 11-10-2018 IPR000743 Glycoside hydrolase, family 28 GO:0004650|GO:0005975 UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 Pfam PF12708 Pectate lyase superfamily protein 54 108 1.2E-6 T 11-10-2018 IPR024535 Pectate lyase superfamily protein UP12_15590 fa0a8b2502bc7d9ff9ba6a39605385f5 463 SUPERFAMILY SSF51126 46 433 2.42E-91 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_06400 4abf9c87b5b5d0cf570761964a3b1cb5 148 Pfam PF01047 MarR family 38 96 1.3E-18 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06400 4abf9c87b5b5d0cf570761964a3b1cb5 148 Gene3D G3DSA:1.10.10.10 1 147 4.1E-39 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06400 4abf9c87b5b5d0cf570761964a3b1cb5 148 SMART SM00347 31 129 1.5E-24 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06400 4abf9c87b5b5d0cf570761964a3b1cb5 148 SUPERFAMILY SSF46785 8 140 4.0E-34 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 Pfam PF00107 Zinc-binding dehydrogenase 162 275 6.2E-17 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 1.3E-5 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 SMART SM00829 12 326 7.5E-6 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 Gene3D G3DSA:3.40.50.720 128 296 3.0E-112 T 11-10-2018 UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 Gene3D G3DSA:3.90.180.10 20 327 3.0E-112 T 11-10-2018 UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 SUPERFAMILY SSF50129 4 145 2.59E-42 T 11-10-2018 IPR011032 GroES-like superfamily UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 SUPERFAMILY SSF51735 118 293 9.09E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_05940 8353e1517a04e526ed2796f1b71c94ae 328 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 5 327 2.2E-128 T 11-10-2018 IPR014188 Acrylyl-CoA reductase AcuI UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF51735 908 1140 1.85E-26 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1261 1276 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF52777 3013 3253 7.45E-52 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF47336 2289 2357 1.7E-14 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF52777 1511 1772 4.22E-62 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.559.10 1324 1698 1.1E-148 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF47336 1230 1303 2.09E-17 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1810 2208 1.7E-121 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.559.10 2362 2543 5.1E-46 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2317 2332 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2675 2823 4.2E-42 T 11-10-2018 IPR010060 Non-ribosomal peptide synthase UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF13193 AMP-binding enzyme C-terminal domain 2192 2265 2.7E-11 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.40.50.12780 84 539 7.9E-126 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.40.50.720 661 1162 6.6E-77 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 908 1096 2.4E-21 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.559.30 1508 1754 1.1E-148 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF56801 1747 2306 1.7E-143 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.559.30 3014 3266 2.4E-129 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.40.50.12780 1778 2178 1.6E-130 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF56801 92 649 1.96E-96 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF00550 Phosphopantetheine attachment site 2296 2356 1.3E-10 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF00550 Phosphopantetheine attachment site 1240 1302 2.7E-12 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:1.10.1200.10 1220 1313 7.5E-24 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:2.30.38.10 3299 3374 1.7E-7 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF52777 2559 2799 1.11E-27 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF08659 KR domain 908 1081 1.5E-37 T 11-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF52777 2833 3012 4.34E-40 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.559.10 2833 3201 2.4E-129 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF00501 AMP-binding enzyme 1789 2184 1.3E-96 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF00501 AMP-binding enzyme 106 545 4.3E-68 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF00668 Condensation domain 2829 3269 1.0E-105 T 11-10-2018 IPR001242 Condensation domain UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF00668 Condensation domain 2373 2801 6.9E-70 T 11-10-2018 IPR001242 Condensation domain UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Pfam PF00668 Condensation domain 1321 1769 6.5E-121 T 11-10-2018 IPR001242 Condensation domain UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF56801 3286 3374 3.66E-5 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.559.30 2544 2803 3.8E-60 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.300.30 2179 2283 2.4E-31 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF52777 2377 2553 1.06E-30 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF51735 667 891 1.65E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 SUPERFAMILY SSF52777 1325 1504 5.11E-50 T 11-10-2018 UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1930 1941 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:1.10.1200.10 2291 2361 2.6E-19 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02015 cf1689095b2f9f76cbfddaa94869ae27 3376 Gene3D G3DSA:3.30.300.30 540 647 5.7E-32 T 11-10-2018 UP12_12940 0d6235366d05117f3518615393c29749 362 SUPERFAMILY SSF53187 7 358 2.51E-74 T 11-10-2018 UP12_12940 0d6235366d05117f3518615393c29749 362 PIRSF PIRSF001123 4 361 1.2E-148 T 11-10-2018 IPR008007 Peptidase M42 UP12_12940 0d6235366d05117f3518615393c29749 362 Gene3D G3DSA:3.40.630.10 12 345 4.6E-137 T 11-10-2018 UP12_12940 0d6235366d05117f3518615393c29749 362 Gene3D G3DSA:2.40.30.40 77 164 4.6E-137 T 11-10-2018 IPR023367 Peptidase M42, domain 2 UP12_12940 0d6235366d05117f3518615393c29749 362 SUPERFAMILY SSF101821 73 182 6.26E-33 T 11-10-2018 UP12_12940 0d6235366d05117f3518615393c29749 362 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 3.6E-118 T 11-10-2018 IPR008007 Peptidase M42 UP12_16950 f468450599705113dad2b66f7e433565 439 SMART SM00984 314 416 1.5E-40 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16950 f468450599705113dad2b66f7e433565 439 SUPERFAMILY SSF52413 303 426 5.36E-33 T 11-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 UP12_16950 f468450599705113dad2b66f7e433565 439 SUPERFAMILY SSF48179 198 292 2.64E-32 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_16950 f468450599705113dad2b66f7e433565 439 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 412 5.5E-135 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UP12_16950 f468450599705113dad2b66f7e433565 439 Gene3D G3DSA:1.20.5.100 197 228 1.2E-18 T 11-10-2018 UP12_16950 f468450599705113dad2b66f7e433565 439 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 290 5.1E-39 T 11-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16950 f468450599705113dad2b66f7e433565 439 Gene3D G3DSA:3.40.50.720 1 196 9.6E-70 T 11-10-2018 UP12_16950 f468450599705113dad2b66f7e433565 439 PIRSF PIRSF000124 1 431 2.5E-140 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UP12_16950 f468450599705113dad2b66f7e433565 439 SUPERFAMILY SSF51735 1 189 6.1E-49 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16950 f468450599705113dad2b66f7e433565 439 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 183 9.6E-61 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16950 f468450599705113dad2b66f7e433565 439 Gene3D G3DSA:3.40.50.720 229 436 1.3E-72 T 11-10-2018 UP12_16950 f468450599705113dad2b66f7e433565 439 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 413 3.8E-30 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16950 f468450599705113dad2b66f7e433565 439 PIRSF PIRSF500134 1 434 2.3E-169 T 11-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 UP12_11085 2ddb1280ac10a2358962ff965544560e 291 SUPERFAMILY SSF52151 6 286 1.94E-42 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_11085 2ddb1280ac10a2358962ff965544560e 291 Gene3D G3DSA:3.40.1090.10 118 289 4.8E-21 T 11-10-2018 UP12_11085 2ddb1280ac10a2358962ff965544560e 291 Gene3D G3DSA:3.40.1090.10 1 117 1.1E-24 T 11-10-2018 UP12_11085 2ddb1280ac10a2358962ff965544560e 291 Pfam PF01734 Patatin-like phospholipase 6 195 7.9E-32 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 UP12_17160 6e01260e5d8731c06f03b1b942a21c89 244 Pfam PF08680 TATA-box binding 46 244 7.5E-57 T 11-10-2018 IPR014794 TATA-box binding UP12_17160 6e01260e5d8731c06f03b1b942a21c89 244 Gene3D G3DSA:3.30.360.40 169 244 1.7E-30 T 11-10-2018 UP12_17160 6e01260e5d8731c06f03b1b942a21c89 244 SUPERFAMILY SSF143842 31 242 5.23E-67 T 11-10-2018 IPR036209 YwmB-like superfamily UP12_17160 6e01260e5d8731c06f03b1b942a21c89 244 Gene3D G3DSA:3.30.2030.10 29 168 4.0E-39 T 11-10-2018 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 11-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 168 1.4E-54 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 SUPERFAMILY SSF48179 176 468 4.08E-132 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 PIRSF PIRSF000109 1 469 1.9E-245 T 11-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 Gene3D G3DSA:1.20.5.320 436 469 2.7E-22 T 11-10-2018 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 Gene3D G3DSA:3.40.50.720 1 179 6.9E-61 T 11-10-2018 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 4.7E-88 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 4.7E-88 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 4.7E-88 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 4.7E-88 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 4.7E-88 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 4.7E-88 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 SUPERFAMILY SSF51735 4 176 2.82E-55 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 SMART SM01350 178 468 4.3E-230 T 11-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 467 4.8E-137 T 11-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 Gene3D G3DSA:1.10.1040.10 180 435 2.0E-111 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_10795 0c8c9ceef7edb15e097abc155b96c796 469 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 6.6E-232 T 11-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 UP12_06150 e7f1ec9d8cdbb74ef9409635f761af2d 182 Pfam PF06114 IrrE N-terminal-like domain 48 147 1.7E-13 T 11-10-2018 IPR010359 IrrE N-terminal-like domain UP12_17315 24b409114d6c71956454aba1cd063867 429 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 42.795 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_17315 24b409114d6c71956454aba1cd063867 429 Gene3D G3DSA:3.65.10.10 6 413 2.2E-159 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UP12_17315 24b409114d6c71956454aba1cd063867 429 SUPERFAMILY SSF55205 1 416 4.41E-136 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 UP12_17315 24b409114d6c71956454aba1cd063867 429 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 7.3E-96 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 UP12_17315 24b409114d6c71956454aba1cd063867 429 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.7E-174 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_17315 24b409114d6c71956454aba1cd063867 429 Gene3D G3DSA:3.65.10.10 21 228 2.2E-159 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 Pfam PF03486 HI0933-like protein 4 412 1.9E-154 T 11-10-2018 UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 Gene3D G3DSA:3.50.50.60 7 408 6.7E-123 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 Gene3D G3DSA:1.10.8.260 278 342 6.7E-123 T 11-10-2018 IPR023166 HI0933-like insert domain superfamily UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 SUPERFAMILY SSF160996 194 360 5.89E-45 T 11-10-2018 UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 SUPERFAMILY SSF51905 2 415 8.27E-63 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.9E-7 T 11-10-2018 UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 367 389 5.9E-7 T 11-10-2018 UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 Gene3D G3DSA:2.40.30.10 193 359 6.7E-123 T 11-10-2018 UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 412 1.6E-144 T 11-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 169 2.8E-9 T 11-10-2018 UP12_13560 fa5bf7e16d3b89e1ed98327249b0bf8e 423 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.8E-9 T 11-10-2018 UP12_08140 d4126180403e3420c71cff29cc9bbea2 116 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 11-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 UP12_08140 d4126180403e3420c71cff29cc9bbea2 116 SUPERFAMILY SSF89919 2 110 3.66E-37 T 11-10-2018 IPR023799 Ribosome-binding factor A domain superfamily UP12_08140 d4126180403e3420c71cff29cc9bbea2 116 Gene3D G3DSA:3.30.300.20 1 115 9.5E-40 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_08140 d4126180403e3420c71cff29cc9bbea2 116 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 107 28.957 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UP12_08140 d4126180403e3420c71cff29cc9bbea2 116 Pfam PF02033 Ribosome-binding factor A 4 107 6.2E-35 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UP12_08140 d4126180403e3420c71cff29cc9bbea2 116 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 112 2.4E-43 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UP12_08140 d4126180403e3420c71cff29cc9bbea2 116 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 2.0E-42 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 UP12_05085 d4469e8d237db8b8e204b4678f096c9b 206 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UP12_05085 d4469e8d237db8b8e204b4678f096c9b 206 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 2 185 47.631 T 11-10-2018 IPR023488 HTH-type transcriptional regulator Hpr UP12_05085 d4469e8d237db8b8e204b4678f096c9b 206 Gene3D G3DSA:1.10.10.10 1 167 2.0E-45 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05085 d4469e8d237db8b8e204b4678f096c9b 206 SUPERFAMILY SSF46785 21 124 2.2E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_05085 d4469e8d237db8b8e204b4678f096c9b 206 Pfam PF01047 MarR family 44 101 1.3E-14 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05085 d4469e8d237db8b8e204b4678f096c9b 206 SMART SM00347 37 137 4.0E-18 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09240 8b015d415afb01bebdee154af834ed56 339 Pfam PF00296 Luciferase-like monooxygenase 27 304 8.9E-37 T 11-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UP12_09240 8b015d415afb01bebdee154af834ed56 339 Gene3D G3DSA:3.20.20.30 7 337 7.0E-98 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_09240 8b015d415afb01bebdee154af834ed56 339 SUPERFAMILY SSF51679 11 331 6.12E-84 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_09240 8b015d415afb01bebdee154af834ed56 339 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 12 331 2.0E-136 T 11-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 UP12_04155 51a24cf5ea8c5f687879e79d4c7abe5f 200 Gene3D G3DSA:2.40.260.10 25 199 1.9E-33 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_04155 51a24cf5ea8c5f687879e79d4c7abe5f 200 Pfam PF04203 Sortase family 70 185 3.8E-22 T 11-10-2018 IPR005754 Sortase family UP12_04155 51a24cf5ea8c5f687879e79d4c7abe5f 200 SUPERFAMILY SSF63817 67 190 1.96E-30 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_04155 51a24cf5ea8c5f687879e79d4c7abe5f 200 TIGRFAM TIGR01076 sortase_fam: sortase 70 193 1.0E-23 T 11-10-2018 IPR005754 Sortase family UP12_12935 904ad6fc8c8634335ad2a280a74fcc00 598 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 416 537 4.3E-29 T 11-10-2018 IPR025299 CstA, C-terminal domain UP12_12935 904ad6fc8c8634335ad2a280a74fcc00 598 Pfam PF02554 Carbon starvation protein CstA 1 371 3.8E-148 T 11-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 UP12_07975 505945f66c2df8ccbeb69a737609bf0f 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 4.5E-33 T 11-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 UP12_07975 505945f66c2df8ccbeb69a737609bf0f 89 PIRSF PIRSF004669 1 89 6.7E-35 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 UP12_07975 505945f66c2df8ccbeb69a737609bf0f 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.5E-29 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 UP12_07975 505945f66c2df8ccbeb69a737609bf0f 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.2E-24 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 UP12_07975 505945f66c2df8ccbeb69a737609bf0f 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.2E-24 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 UP12_07975 505945f66c2df8ccbeb69a737609bf0f 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.2E-24 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 SUPERFAMILY SSF109998 250 423 6.41E-43 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 2.0E-46 T 11-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 TIGRFAM TIGR00115 tig: trigger factor 12 421 1.3E-143 T 11-10-2018 IPR005215 Trigger factor GO:0015031 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 PIRSF PIRSF003095 1 424 2.7E-139 T 11-10-2018 IPR005215 Trigger factor GO:0015031 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 Gene3D G3DSA:1.10.3120.10 117 423 2.2E-96 T 11-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 SUPERFAMILY SSF102735 1 129 1.28E-39 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 Hamap MF_00303 Trigger factor [tig]. 1 424 23.862 T 11-10-2018 IPR005215 Trigger factor GO:0015031 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 Gene3D G3DSA:3.10.50.40 151 248 2.2E-96 T 11-10-2018 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 1.7E-47 T 11-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 SUPERFAMILY SSF54534 89 243 3.93E-38 T 11-10-2018 UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 3.6E-15 T 11-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain UP12_12390 2767c419f336af8ce18dcb65e90e047f 424 Gene3D G3DSA:3.30.70.1050 1 116 3.2E-32 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 502 637 1.0E-26 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Gene3D G3DSA:1.10.10.10 3 69 6.3E-8 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Gene3D G3DSA:1.10.1790.10 297 394 8.4E-15 T 11-10-2018 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Gene3D G3DSA:1.10.10.10 83 157 8.9E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Pfam PF05043 Mga helix-turn-helix domain 95 170 2.0E-11 T 11-10-2018 IPR007737 Mga helix-turn-helix domain UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Pfam PF08279 HTH domain 8 65 1.1E-6 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 SUPERFAMILY SSF63520 295 392 2.09E-16 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Gene3D G3DSA:1.10.1790.10 189 286 7.8E-11 T 11-10-2018 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 SUPERFAMILY SSF52794 402 482 2.67E-8 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Gene3D G3DSA:3.40.930.10 497 639 2.2E-24 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 SUPERFAMILY SSF46785 92 155 2.31E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Pfam PF00874 PRD domain 306 391 1.1E-15 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Pfam PF00874 PRD domain 209 283 3.0E-11 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 Gene3D G3DSA:3.40.50.2300 403 490 4.0E-9 T 11-10-2018 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 SUPERFAMILY SSF55804 499 638 5.49E-30 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_01405 9a0b6f04120cbb1918a0e9ee0e5ec7f4 639 SUPERFAMILY SSF63520 193 285 3.79E-12 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 SUPERFAMILY SSF53067 1 157 1.15E-57 T 11-10-2018 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 Gene3D G3DSA:2.60.34.10 348 476 2.7E-59 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 606 37.421 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 3.6E-287 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 Gene3D G3DSA:1.20.1270.10 477 580 1.1E-24 T 11-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 SUPERFAMILY SSF100920 354 510 6.93E-63 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 Gene3D G3DSA:3.90.640.10 198 279 1.3E-152 T 11-10-2018 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 53 61 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 358 377 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 439 455 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 172 182 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 304 320 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 112 132 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 PRINTS PR00301 70kDa heat shock protein signature 335 355 1.9E-78 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 SUPERFAMILY SSF53067 160 351 4.44E-68 T 11-10-2018 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 SUPERFAMILY SSF100934 477 580 3.27E-13 T 11-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 Gene3D G3DSA:3.30.420.40 159 337 1.3E-152 T 11-10-2018 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 Pfam PF00012 Hsp70 protein 76 573 3.9E-224 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UP12_11560 2424677ff09b069cb1b4d155be5d0eb1 613 Gene3D G3DSA:3.30.420.40 5 347 1.3E-152 T 11-10-2018 UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 SUPERFAMILY SSF47336 783 861 1.31E-16 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 295 692 1.2E-113 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 PRINTS PR00154 AMP-binding signature 406 417 6.9E-5 T 11-10-2018 IPR020459 AMP-binding UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 PRINTS PR00154 AMP-binding signature 418 426 6.9E-5 T 11-10-2018 IPR020459 AMP-binding UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 ProSitePatterns PS00455 Putative AMP-binding domain signature. 411 422 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 Pfam PF00550 Phosphopantetheine attachment site 788 853 4.8E-15 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 SUPERFAMILY SSF56801 232 800 4.06E-133 T 11-10-2018 UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 SMART SM00823 Phosphopantetheine attachment site 787 858 2.9E-4 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 Pfam PF00501 AMP-binding enzyme 274 673 8.3E-87 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 SUPERFAMILY SSF52777 18 237 5.23E-21 T 11-10-2018 UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 Gene3D G3DSA:3.30.300.30 668 775 5.2E-26 T 11-10-2018 UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 Pfam PF00668 Condensation domain 12 253 2.0E-17 T 11-10-2018 IPR001242 Condensation domain UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 Gene3D G3DSA:1.10.1200.10 779 864 4.1E-17 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 Gene3D G3DSA:3.40.50.12780 261 667 7.1E-115 T 11-10-2018 UP12_03535 8b15670f3fe7f4ec3286e53e61299d39 889 Gene3D G3DSA:3.30.559.30 16 259 2.8E-26 T 11-10-2018 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 PIRSF PIRSF000102 3 313 3.7E-115 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 SUPERFAMILY SSF51735 4 146 2.64E-56 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 4.5E-50 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 4.5E-50 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 PRINTS PR00086 L-lactate dehydrogenase signature 8 32 4.5E-50 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 4.5E-50 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 4.5E-50 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 Gene3D G3DSA:3.90.110.10 149 314 2.2E-66 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 6 315 47.674 T 11-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 11-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 312 2.4E-42 T 11-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 8 146 8.5E-50 T 11-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 SUPERFAMILY SSF56327 147 311 1.67E-59 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 11 309 2.5E-134 T 11-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 UP12_01715 c150e7c771c76db0a04229b7df2fa99b 315 Gene3D G3DSA:3.40.50.720 1 148 2.5E-58 T 11-10-2018 UP12_05045 db6aac16c94d95eb9a3b27b8e25e6f21 929 Gene3D G3DSA:3.40.50.300 703 925 3.8E-15 T 11-10-2018 UP12_05045 db6aac16c94d95eb9a3b27b8e25e6f21 929 Gene3D G3DSA:3.40.50.300 1 257 3.7E-20 T 11-10-2018 UP12_05045 db6aac16c94d95eb9a3b27b8e25e6f21 929 Pfam PF13514 AAA domain 1 200 9.8E-27 T 11-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain UP12_05045 db6aac16c94d95eb9a3b27b8e25e6f21 929 SUPERFAMILY SSF52540 1 922 1.84E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06185 723cae3462260eff60754a8eea5fe78c 583 Gene3D G3DSA:1.10.246.130 269 396 2.3E-50 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 SUPERFAMILY SSF56235 34 576 8.88E-177 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_06185 723cae3462260eff60754a8eea5fe78c 583 Pfam PF01019 Gamma-glutamyltranspeptidase 56 571 4.6E-170 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 41 569 7.3E-202 T 11-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 Gene3D G3DSA:3.60.20.40 397 575 2.1E-71 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 63 88 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 283 302 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 397 415 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 476 493 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 421 439 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 452 467 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 138 156 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 156 175 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 253 269 1.2E-75 T 11-10-2018 UP12_06185 723cae3462260eff60754a8eea5fe78c 583 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 397 421 - T 11-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 SUPERFAMILY SSF50156 335 450 3.42E-21 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 Pfam PF13365 Trypsin-like peptidase domain 169 313 2.9E-32 T 11-10-2018 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 Pfam PF13180 PDZ domain 351 450 6.3E-19 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 Gene3D G3DSA:2.40.10.10 115 231 2.1E-27 T 11-10-2018 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 SMART SM00228 351 441 3.7E-14 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 Gene3D G3DSA:2.40.10.10 234 350 1.2E-42 T 11-10-2018 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 Gene3D G3DSA:2.30.42.10 351 456 1.0E-26 T 11-10-2018 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 PRINTS PR00834 HtrA/DegQ protease family signature 284 301 6.8E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 PRINTS PR00834 HtrA/DegQ protease family signature 306 323 6.8E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 PRINTS PR00834 HtrA/DegQ protease family signature 398 410 6.8E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 PRINTS PR00834 HtrA/DegQ protease family signature 202 222 6.8E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 PRINTS PR00834 HtrA/DegQ protease family signature 181 193 6.8E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 PRINTS PR00834 HtrA/DegQ protease family signature 243 267 6.8E-41 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_15495 fec2bd365a05566df2921ce9d9a1645a 456 SUPERFAMILY SSF50494 130 348 7.45E-58 T 11-10-2018 IPR009003 Peptidase S1, PA clan UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 268 355 1.1E-5 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 Gene3D G3DSA:3.40.710.10 32 267 1.1E-88 T 11-10-2018 UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 Gene3D G3DSA:2.30.140.30 268 359 2.3E-28 T 11-10-2018 UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 SUPERFAMILY SSF56601 3 268 7.15E-65 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 251 2.5E-74 T 11-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 108 125 3.9E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 3.9E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_10435 5a87ac7c8557cdc3f06fb7735861dfdf 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 135 148 3.9E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_09410 8718496c359af75acd3f701246913dad 190 Gene3D G3DSA:1.10.357.10 51 183 4.3E-27 T 11-10-2018 UP12_09410 8718496c359af75acd3f701246913dad 190 SUPERFAMILY SSF48498 80 181 9.64E-19 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_09410 8718496c359af75acd3f701246913dad 190 SUPERFAMILY SSF46689 6 69 3.08E-11 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_09410 8718496c359af75acd3f701246913dad 190 Pfam PF13305 WHG domain 85 158 2.1E-13 T 11-10-2018 IPR025996 WHG domain UP12_09410 8718496c359af75acd3f701246913dad 190 Gene3D G3DSA:1.10.10.60 1 50 8.9E-21 T 11-10-2018 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 SUPERFAMILY SSF50447 263 402 7.07E-36 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 7.0E-16 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Pfam PF00679 Elongation factor G C-terminus 598 684 3.2E-32 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 SUPERFAMILY SSF54211 477 597 4.05E-43 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Gene3D G3DSA:3.30.70.240 602 672 8.7E-95 T 11-10-2018 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 SMART SM00838 598 685 1.8E-59 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 SUPERFAMILY SSF52540 6 279 2.06E-110 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Gene3D G3DSA:3.40.50.300 1 292 1.4E-113 T 11-10-2018 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Gene3D G3DSA:3.30.70.870 404 481 3.3E-32 T 11-10-2018 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 279 6.6E-70 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 SUPERFAMILY SSF54980 400 478 2.95E-25 T 11-10-2018 IPR035647 EF-G domain III/V-like UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Pfam PF14492 Elongation Factor G, domain II 402 475 9.7E-36 T 11-10-2018 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 SUPERFAMILY SSF54980 598 688 3.02E-31 T 11-10-2018 IPR035647 EF-G domain III/V-like UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 113.59 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 SMART SM00889 478 596 1.2E-72 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 5.6E-47 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Gene3D G3DSA:2.40.30.10 293 403 7.8E-47 T 11-10-2018 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Pfam PF03764 Elongation factor G, domain IV 477 595 3.7E-46 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 Gene3D G3DSA:3.30.230.10 482 685 8.7E-95 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00705 90035e675c73ea0c6f046a505879ef6f 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_02195 7840b1d3c773f71e6bf9367e1968f8ca 544 Pfam PF05425 Copper resistance protein D 331 422 8.5E-16 T 11-10-2018 IPR008457 Copper resistance protein D GO:0016021 UP12_02195 7840b1d3c773f71e6bf9367e1968f8ca 544 Gene3D G3DSA:2.60.40.1220 26 125 5.2E-26 T 11-10-2018 UP12_02195 7840b1d3c773f71e6bf9367e1968f8ca 544 Pfam PF04234 CopC domain 26 120 2.9E-21 T 11-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 UP12_02195 7840b1d3c773f71e6bf9367e1968f8ca 544 SUPERFAMILY SSF81296 25 120 4.76E-23 T 11-10-2018 IPR014756 Immunoglobulin E-set UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 SUPERFAMILY SSF53383 4 379 3.23E-113 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 Pfam PF00155 Aminotransferase class I and II 29 375 1.6E-64 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 195 218 5.4E-11 T 11-10-2018 UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 159 183 5.4E-11 T 11-10-2018 UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 113 134 5.4E-11 T 11-10-2018 UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 91 111 5.4E-11 T 11-10-2018 UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 Gene3D G3DSA:3.40.640.10 58 278 3.6E-129 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 Gene3D G3DSA:3.90.1150.10 29 375 3.6E-129 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_06755 a2ae3754f2f948b46176ae9554afc50a 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 228 241 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 218 6.6E-14 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 Gene3D G3DSA:1.10.540.10 7 126 8.3E-21 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 Gene3D G3DSA:1.20.140.10 241 381 3.3E-25 T 11-10-2018 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 SUPERFAMILY SSF56645 22 226 2.49E-43 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 98 2.2E-10 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 Gene3D G3DSA:2.40.110.10 136 226 5.0E-21 T 11-10-2018 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 248 362 7.0E-15 T 11-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 PIRSF PIRSF016578 4 106 3.2E-8 T 11-10-2018 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 PIRSF PIRSF016578 138 387 2.4E-24 T 11-10-2018 UP12_11810 a9f378108731a18541bca8f77cdcfd54 387 SUPERFAMILY SSF47203 236 382 2.74E-23 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-5 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 Gene3D G3DSA:3.40.190.290 85 287 1.7E-67 T 11-10-2018 UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 Gene3D G3DSA:1.10.10.10 1 84 1.6E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 SUPERFAMILY SSF46785 1 87 5.64E-17 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 Pfam PF03466 LysR substrate binding domain 87 288 1.9E-30 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 SUPERFAMILY SSF53850 88 290 9.45E-27 T 11-10-2018 UP12_06845 bc013885099f019f17fbb9a43bc4ba81 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.3E-14 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 SMART SM00304 176 230 0.0015 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 446 7.1E-23 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 SUPERFAMILY SSF55874 288 447 4.45E-40 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 Gene3D G3DSA:1.10.287.130 180 297 1.3E-24 T 11-10-2018 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 Gene3D G3DSA:3.30.565.10 301 449 4.3E-37 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 SMART SM00388 231 298 2.3E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 SMART SM00387 341 449 1.6E-33 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 297 4.7E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 SUPERFAMILY SSF47384 215 295 2.35E-16 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 2.6E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 404 2.6E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 2.6E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06430 9eaf8483d1862b252beac134e0bce9a3 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 2.6E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 Gene3D G3DSA:3.40.50.970 366 563 2.2E-56 T 11-10-2018 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 12 549 2.0E-249 T 11-10-2018 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 SUPERFAMILY SSF52467 190 353 2.97E-31 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 429 448 - T 11-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 538 4.0E-42 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 SUPERFAMILY SSF52518 366 553 8.84E-58 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 Gene3D G3DSA:3.40.50.970 1 186 8.3E-68 T 11-10-2018 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 332 5.9E-27 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 SUPERFAMILY SSF52518 7 183 1.18E-49 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 Gene3D G3DSA:3.40.50.1220 188 363 2.2E-37 T 11-10-2018 UP12_16925 bd545bb8c596efb7b6cddb3e4e1b41cb 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 177 1.6E-52 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UP12_07785 b6de24bcbc0735a3c445f989fb3e4694 90 Pfam PF00886 Ribosomal protein S16 9 67 3.3E-25 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07785 b6de24bcbc0735a3c445f989fb3e4694 90 Gene3D G3DSA:3.30.1320.10 1 90 1.3E-36 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07785 b6de24bcbc0735a3c445f989fb3e4694 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 24.71 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07785 b6de24bcbc0735a3c445f989fb3e4694 90 SUPERFAMILY SSF54565 2 86 4.32E-34 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07785 b6de24bcbc0735a3c445f989fb3e4694 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 5.3E-35 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_09835 22bb7cbd8e836cbb0588ed1d272eb205 302 PIRSF PIRSF000450 1 302 7.0E-146 T 11-10-2018 IPR033752 MetA family UP12_09835 22bb7cbd8e836cbb0588ed1d272eb205 302 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 299 43.392 T 11-10-2018 IPR033752 MetA family UP12_09835 22bb7cbd8e836cbb0588ed1d272eb205 302 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 1.0E-118 T 11-10-2018 UP12_09835 22bb7cbd8e836cbb0588ed1d272eb205 302 SUPERFAMILY SSF52317 17 297 2.4E-101 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_09835 22bb7cbd8e836cbb0588ed1d272eb205 302 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 1.1E-126 T 11-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 UP12_09835 22bb7cbd8e836cbb0588ed1d272eb205 302 Pfam PF04204 Homoserine O-succinyltransferase 2 299 2.9E-138 T 11-10-2018 IPR033752 MetA family UP12_09835 22bb7cbd8e836cbb0588ed1d272eb205 302 Gene3D G3DSA:3.40.50.880 1 301 1.9E-125 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_12970 1e6f89bebd518c99a3530262aac6b304 226 Pfam PF04172 LrgB-like family 10 223 4.1E-70 T 11-10-2018 IPR007300 CidB/LrgB family UP12_12970 1e6f89bebd518c99a3530262aac6b304 226 Hamap MF_01142 Antiholin-like protein LrgB [lrgB]. 1 226 31.11 T 11-10-2018 IPR024891 Antiholin-like protein LrgB UP12_03225 a5eddc749c9de2597bd08e6532a3ad71 122 Pfam PF03330 Lytic transglycolase 31 120 1.5E-7 T 11-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain UP12_03225 a5eddc749c9de2597bd08e6532a3ad71 122 Gene3D G3DSA:2.40.40.10 30 122 9.9E-6 T 11-10-2018 IPR036908 RlpA-like domain superfamily UP12_08145 3f0fdbc5271b41859a11cd007ed59dda 309 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 2 217 1.5E-87 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_08145 3f0fdbc5271b41859a11cd007ed59dda 309 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 178 8.9E-59 T 11-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 UP12_08145 3f0fdbc5271b41859a11cd007ed59dda 309 SUPERFAMILY SSF55120 1 237 9.5E-82 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_08145 3f0fdbc5271b41859a11cd007ed59dda 309 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 2.4E-16 T 11-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 UP12_08145 3f0fdbc5271b41859a11cd007ed59dda 309 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 303 19.608 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_08145 3f0fdbc5271b41859a11cd007ed59dda 309 Gene3D G3DSA:3.30.2350.10 1 242 4.6E-93 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.300.30 2917 3015 4.7E-31 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1648 1659 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00501 AMP-binding enzyme 1506 1903 1.2E-99 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00501 AMP-binding enzyme 464 869 5.8E-100 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00501 AMP-binding enzyme 2548 2922 8.9E-85 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3412 3564 6.2E-46 T 11-10-2018 IPR010060 Non-ribosomal peptide synthase UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00550 Phosphopantetheine attachment site 980 1043 1.3E-11 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00550 Phosphopantetheine attachment site 2010 2069 2.7E-9 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00550 Phosphopantetheine attachment site 3030 3087 1.4E-10 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF47336 970 1044 3.89E-18 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF13193 AMP-binding enzyme C-terminal domain 2930 3001 1.0E-10 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF13193 AMP-binding enzyme C-terminal domain 1911 1980 7.1E-9 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF13193 AMP-binding enzyme C-terminal domain 877 951 2.0E-5 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.30 2261 2506 3.1E-132 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.10 3095 3274 1.1E-57 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.10 2093 2451 3.1E-132 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.30 186 427 4.6E-77 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 2090 2277 3.34E-40 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.40.50.12780 2528 2916 6.3E-119 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.10 1064 1414 1.3E-134 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.40.50.12780 1496 1895 6.5E-127 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF47336 3019 3092 7.72E-19 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF56801 1463 2019 6.15E-146 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:1.10.1200.10 1996 2080 1.6E-23 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:1.10.1200.10 966 1051 8.1E-24 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 1226 1469 3.89E-61 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2031 2046 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.10 7 371 4.6E-77 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SMART SM00823 Phosphopantetheine attachment site 978 1047 0.033 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SMART SM00823 Phosphopantetheine attachment site 3027 3095 0.019 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 3293 3540 1.89E-35 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 2264 2511 7.0E-56 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF56801 423 990 7.59E-144 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.40.50.12780 457 862 4.4E-124 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 485 893 8.3E-128 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2563 2946 3.3E-119 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1527 1927 3.5E-122 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 188 427 3.34E-43 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.300.30 863 965 2.4E-28 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 604 615 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF56801 2499 3040 3.14E-146 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2679 2690 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 1059 1225 2.78E-41 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00668 Condensation domain 1061 1484 8.5E-120 T 11-10-2018 IPR001242 Condensation domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00668 Condensation domain 2091 2522 8.6E-127 T 11-10-2018 IPR001242 Condensation domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00668 Condensation domain 3105 3557 7.5E-110 T 11-10-2018 IPR001242 Condensation domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Pfam PF00668 Condensation domain 6 444 6.4E-98 T 11-10-2018 IPR001242 Condensation domain UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF47336 1999 2070 6.67E-17 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.300.30 1896 1995 1.4E-29 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.30 3275 3546 1.6E-67 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:3.30.559.30 1228 1470 1.3E-134 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 Gene3D G3DSA:1.10.1200.10 3016 3094 3.5E-23 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 8 182 3.89E-27 T 11-10-2018 UP12_02000 d086f33a6bb6faeeea16efe6bdacbe87 3568 SUPERFAMILY SSF52777 3111 3284 5.56E-36 T 11-10-2018 UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 Pfam PF01047 MarR family 31 88 4.9E-16 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 Gene3D G3DSA:1.10.10.10 1 139 3.6E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 1.7E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 1.7E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 1.7E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 1.7E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 SUPERFAMILY SSF46785 2 138 1.05E-30 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_05945 5d3345306ac0d52ef49514e7e828cf71 139 SMART SM00347 24 124 1.5E-20 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_02100 41fef20135975717dacd1b29c345d7a6 441 SUPERFAMILY SSF51679 5 435 1.31E-136 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_02100 41fef20135975717dacd1b29c345d7a6 441 PIRSF PIRSF000337 3 441 2.1E-163 T 11-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 UP12_02100 41fef20135975717dacd1b29c345d7a6 441 Gene3D G3DSA:3.20.20.30 1 441 5.1E-163 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_02100 41fef20135975717dacd1b29c345d7a6 441 Pfam PF00296 Luciferase-like monooxygenase 19 381 8.6E-69 T 11-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UP12_02100 41fef20135975717dacd1b29c345d7a6 441 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 429 1.4E-182 T 11-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 UP12_14955 00a067c7dbbb0c7b8aac498d1ce46b31 129 SUPERFAMILY SSF54637 7 128 3.56E-32 T 11-10-2018 IPR029069 HotDog domain superfamily UP12_14955 00a067c7dbbb0c7b8aac498d1ce46b31 129 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 125 5.1E-39 T 11-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 UP12_14955 00a067c7dbbb0c7b8aac498d1ce46b31 129 Pfam PF03061 Thioesterase superfamily 39 115 5.6E-17 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UP12_14955 00a067c7dbbb0c7b8aac498d1ce46b31 129 Gene3D G3DSA:3.10.129.10 1 129 8.0E-51 T 11-10-2018 UP12_12215 42007f24024621bc366b1b82c4624638 180 Pfam PF08279 HTH domain 12 64 1.5E-14 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_12215 42007f24024621bc366b1b82c4624638 180 Gene3D G3DSA:1.10.10.10 1 67 1.6E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_12215 42007f24024621bc366b1b82c4624638 180 PIRSF PIRSF037847 7 180 3.6E-67 T 11-10-2018 IPR026043 Transcription repressor NadR UP12_12215 42007f24024621bc366b1b82c4624638 180 SUPERFAMILY SSF46785 9 67 6.43E-9 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_12215 42007f24024621bc366b1b82c4624638 180 Gene3D G3DSA:3.30.1340.20 74 180 1.2E-33 T 11-10-2018 IPR035922 3H domain superfamily UP12_12215 42007f24024621bc366b1b82c4624638 180 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 85 178 5.0E-32 T 11-10-2018 IPR004173 3H domain GO:0036094 UP12_12215 42007f24024621bc366b1b82c4624638 180 SUPERFAMILY SSF75500 77 179 1.03E-33 T 11-10-2018 IPR035922 3H domain superfamily UP12_12215 42007f24024621bc366b1b82c4624638 180 Pfam PF02829 3H domain 81 177 2.1E-32 T 11-10-2018 IPR004173 3H domain GO:0036094 UP12_05405 69d98640243f90992847b66402d4fd4a 505 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 3 497 1.1E-143 T 11-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 UP12_05405 69d98640243f90992847b66402d4fd4a 505 Gene3D G3DSA:3.50.50.60 199 322 4.2E-17 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05405 69d98640243f90992847b66402d4fd4a 505 Gene3D G3DSA:3.50.50.60 1 88 8.1E-23 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05405 69d98640243f90992847b66402d4fd4a 505 Pfam PF01593 Flavin containing amine oxidoreductase 11 485 3.4E-26 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UP12_05405 69d98640243f90992847b66402d4fd4a 505 SUPERFAMILY SSF51905 1 487 2.43E-64 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05405 69d98640243f90992847b66402d4fd4a 505 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 2.2E-8 T 11-10-2018 UP12_05405 69d98640243f90992847b66402d4fd4a 505 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 2.2E-8 T 11-10-2018 UP12_13610 1a789212fdd4392512684213c1867835 321 SUPERFAMILY SSF161098 77 306 1.31E-47 T 11-10-2018 IPR035906 MetI-like superfamily UP12_13610 1a789212fdd4392512684213c1867835 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 314 1.3E-13 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_13610 1a789212fdd4392512684213c1867835 321 Gene3D G3DSA:1.10.3720.10 73 321 1.2E-59 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15240 027372ce15351922c10a8443a290d15e 326 SUPERFAMILY SSF51261 123 315 4.08E-34 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_15240 027372ce15351922c10a8443a290d15e 326 Pfam PF01551 Peptidase family M23 204 302 7.8E-20 T 11-10-2018 IPR016047 Peptidase M23 UP12_15240 027372ce15351922c10a8443a290d15e 326 Gene3D G3DSA:2.70.70.10 149 326 3.0E-53 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 SUPERFAMILY SSF51261 468 614 9.94E-53 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 SUPERFAMILY SSF55604 6 79 1.44E-18 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 470 595 3.0E-49 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 Gene3D G3DSA:2.70.70.10 460 616 8.3E-53 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 Pfam PF00367 phosphotransferase system, EIIB 8 41 2.1E-13 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 533 545 - T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 Pfam PF02378 Phosphotransferase system, EIIC 111 379 4.7E-28 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 Gene3D G3DSA:3.30.1360.60 1 76 1.3E-22 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 473 591 2.1E-43 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_18625 1b8e07053a95ff34624c0a8fb08ded3f 619 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 614 1.1E-219 T 11-10-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 SUPERFAMILY SSF54909 73 151 2.15E-11 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 Pfam PF01037 Lrp/AsnC ligand binding domain 79 148 6.2E-9 T 11-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 Gene3D G3DSA:3.30.70.920 66 158 1.4E-13 T 11-10-2018 UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 11-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 SMART SM00344 12 118 1.2E-40 T 11-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 Gene3D G3DSA:1.10.10.10 2 65 2.0E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 5.2E-15 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 5.2E-15 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 5.2E-15 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 Pfam PF13404 AsnC-type helix-turn-helix domain 12 52 6.9E-15 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_16935 6858a06cbb71c61f94f1f5d9d04fcf65 158 SUPERFAMILY SSF46785 11 71 8.32E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_16345 9b8cdb10994f486aaff799d95e73b23f 1285 Pfam PF00149 Calcineurin-like phosphoesterase 929 1121 5.0E-11 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_16345 9b8cdb10994f486aaff799d95e73b23f 1285 SUPERFAMILY SSF74853 152 233 1.44E-5 T 11-10-2018 IPR036415 Lamin tail domain superfamily UP12_16345 9b8cdb10994f486aaff799d95e73b23f 1285 Pfam PF00932 Lamin Tail Domain 153 239 4.2E-11 T 11-10-2018 IPR001322 Lamin tail domain UP12_16345 9b8cdb10994f486aaff799d95e73b23f 1285 SUPERFAMILY SSF56300 924 1172 2.48E-36 T 11-10-2018 UP12_16345 9b8cdb10994f486aaff799d95e73b23f 1285 Gene3D G3DSA:3.60.21.10 926 1145 1.6E-17 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_16345 9b8cdb10994f486aaff799d95e73b23f 1285 Gene3D G3DSA:2.60.40.10 652 741 5.6E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Gene3D G3DSA:3.30.54.20 626 679 4.1E-51 T 11-10-2018 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Gene3D G3DSA:2.40.30.130 477 556 7.0E-10 T 11-10-2018 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 SUPERFAMILY SSF55681 5 245 8.2E-89 T 11-10-2018 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Pfam PF02272 DHHA1 domain 735 873 8.5E-31 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Gene3D G3DSA:3.30.980.10 564 699 4.1E-51 T 11-10-2018 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 SMART SM00863 655 698 1.4E-21 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 878 185.146 T 11-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Gene3D G3DSA:3.30.930.10 3 242 9.8E-94 T 11-10-2018 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 9.2E-19 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Gene3D G3DSA:3.10.310.40 766 876 2.4E-36 T 11-10-2018 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 4.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 4.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 4.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 4.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 4.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 Pfam PF01411 tRNA synthetases class II (A) 8 556 3.7E-212 T 11-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 SUPERFAMILY SSF55186 556 720 7.06E-53 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 UP12_11985 4b8717296ac4e79923ae015a47d54606 878 SUPERFAMILY SSF50447 455 554 9.42E-19 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_11985 4b8717296ac4e79923ae015a47d54606 878 SUPERFAMILY SSF101353 246 438 1.44E-69 T 11-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 SUPERFAMILY SSF55681 244 526 1.19E-93 T 11-10-2018 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Pfam PF02824 TGS domain 6 65 7.7E-12 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 70 634 34.453 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Gene3D G3DSA:3.30.54.20 134 188 6.9E-63 T 11-10-2018 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Gene3D G3DSA:3.30.980.10 73 223 6.9E-63 T 11-10-2018 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Pfam PF03129 Anticodon binding domain 541 627 3.8E-21 T 11-10-2018 IPR004154 Anticodon-binding UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 SUPERFAMILY SSF81271 6 65 1.92E-15 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 SUPERFAMILY SSF52954 530 634 1.45E-29 T 11-10-2018 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 SUPERFAMILY SSF55186 67 241 5.23E-62 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Gene3D G3DSA:3.30.930.10 224 531 2.9E-131 T 11-10-2018 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 76 630 1.8E-234 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 363 386 1.7E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 1.7E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 1.7E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 1.7E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 330 358 1.7E-52 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 220 1.6E-14 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 SMART SM00863 171 220 5.1E-22 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Gene3D G3DSA:3.10.20.30 4 66 5.2E-23 T 11-10-2018 IPR012675 Beta-grasp domain superfamily UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Gene3D G3DSA:3.40.50.800 532 642 2.9E-32 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily UP12_04125 ea741ab370303fc3db6471a9dc4f4219 643 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 325 528 2.0E-38 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_14650 385544817d6c1d9bee7a8ba2e358cabc 172 Gene3D G3DSA:1.10.10.10 84 166 2.4E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_14650 385544817d6c1d9bee7a8ba2e358cabc 172 Pfam PF08281 Sigma-70, region 4 108 159 1.7E-13 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_14650 385544817d6c1d9bee7a8ba2e358cabc 172 SUPERFAMILY SSF88659 108 165 5.67E-13 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_14650 385544817d6c1d9bee7a8ba2e358cabc 172 SMART SM00421 113 171 0.0073 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_14650 385544817d6c1d9bee7a8ba2e358cabc 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 162 7.0E-14 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Pfam PF01624 MutS domain I 5 113 5.4E-45 T 11-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 4 850 25.422 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Gene3D G3DSA:3.40.1170.10 1 114 1.1E-47 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Gene3D G3DSA:1.10.1420.10 250 545 1.3E-100 T 11-10-2018 UP12_08355 f932db7fe29759a9235b54c516f72360 858 SUPERFAMILY SSF55271 2 109 4.71E-42 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Pfam PF00488 MutS domain V 597 783 9.8E-85 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 SMART SM00533 268 576 5.0E-114 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 PIRSF PIRSF037677 175 837 3.9E-130 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 PIRSF PIRSF037677 1 205 3.2E-34 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Gene3D G3DSA:1.10.1420.10 385 521 1.3E-100 T 11-10-2018 UP12_08355 f932db7fe29759a9235b54c516f72360 858 SUPERFAMILY SSF48334 251 549 1.83E-87 T 11-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily UP12_08355 f932db7fe29759a9235b54c516f72360 858 SMART SM00534 593 780 5.0E-119 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 674 690 - T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 SUPERFAMILY SSF52540 553 784 1.17E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08355 f932db7fe29759a9235b54c516f72360 858 Pfam PF05190 MutS family domain IV 413 504 2.5E-30 T 11-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Gene3D G3DSA:3.30.420.110 121 244 3.6E-15 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Pfam PF05192 MutS domain III 256 545 7.6E-45 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Gene3D G3DSA:3.40.50.300 554 857 1.7E-103 T 11-10-2018 UP12_08355 f932db7fe29759a9235b54c516f72360 858 SUPERFAMILY SSF53150 111 264 2.49E-30 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 Pfam PF05188 MutS domain II 122 237 1.4E-11 T 11-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 UP12_08355 f932db7fe29759a9235b54c516f72360 858 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 4 856 0.0 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 UP12_12980 a94213fcf91c595f7940082ffef89e31 245 Pfam PF04397 LytTr DNA-binding domain 147 242 2.4E-27 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UP12_12980 a94213fcf91c595f7940082ffef89e31 245 SUPERFAMILY SSF52172 3 154 2.7E-30 T 11-10-2018 IPR011006 CheY-like superfamily UP12_12980 a94213fcf91c595f7940082ffef89e31 245 Gene3D G3DSA:2.40.50.40 137 206 9.7E-16 T 11-10-2018 UP12_12980 a94213fcf91c595f7940082ffef89e31 245 SMART SM00448 2 113 7.2E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_12980 a94213fcf91c595f7940082ffef89e31 245 SMART SM00850 146 243 2.2E-34 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UP12_12980 a94213fcf91c595f7940082ffef89e31 245 Gene3D G3DSA:2.20.25.10 207 244 8.3E-8 T 11-10-2018 UP12_12980 a94213fcf91c595f7940082ffef89e31 245 Gene3D G3DSA:3.40.50.2300 1 133 5.3E-31 T 11-10-2018 UP12_12980 a94213fcf91c595f7940082ffef89e31 245 Pfam PF00072 Response regulator receiver domain 4 113 9.3E-24 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 11-10-2018 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Pfam PF02810 SEC-C motif 821 839 1.4E-7 T 11-10-2018 IPR004027 SEC-C motif UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Gene3D G3DSA:1.10.3060.10 571 773 0.0 T 11-10-2018 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Pfam PF07517 SecA DEAD-like domain 7 382 5.3E-127 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 ProSitePatterns PS01312 SecA family signature. 480 495 - T 11-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 SUPERFAMILY SSF52540 7 395 1.1E-82 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Gene3D G3DSA:3.40.50.300 15 396 0.0 T 11-10-2018 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 SUPERFAMILY SSF81767 225 348 2.49E-45 T 11-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 SUPERFAMILY SSF81886 571 829 2.09E-79 T 11-10-2018 IPR036266 SecA, Wing/Scaffold superfamily UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 SMART SM00958 226 338 2.1E-65 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 1.5E-242 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 19.589 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 SUPERFAMILY SSF52540 397 568 9.28E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 SMART SM00957 5 382 1.1E-279 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Gene3D G3DSA:3.40.50.300 397 570 0.0 T 11-10-2018 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Gene3D G3DSA:1.10.1200.230 621 705 0.0 T 11-10-2018 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Pfam PF07516 SecA Wing and Scaffold domain 568 777 4.5E-64 T 11-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Gene3D G3DSA:3.10.450.50 774 840 3.7E-8 T 11-10-2018 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 Pfam PF01043 SecA preprotein cross-linking domain 230 338 8.9E-41 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 PRINTS PR00906 SecA protein signature 393 406 1.7E-70 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 PRINTS PR00906 SecA protein signature 115 125 1.7E-70 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 PRINTS PR00906 SecA protein signature 356 373 1.7E-70 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 PRINTS PR00906 SecA protein signature 168 188 1.7E-70 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 PRINTS PR00906 SecA protein signature 61 85 1.7E-70 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 PRINTS PR00906 SecA protein signature 99 113 1.7E-70 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_16500 35e309d4b6689103aa68cc62f459d95c 841 PRINTS PR00906 SecA protein signature 319 341 1.7E-70 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 UP12_09380 34ad85c34d8997e141ef940b2d77cb91 463 Gene3D G3DSA:1.20.1250.20 16 214 3.3E-16 T 11-10-2018 UP12_09380 34ad85c34d8997e141ef940b2d77cb91 463 Gene3D G3DSA:1.20.1250.20 232 429 1.9E-10 T 11-10-2018 UP12_09380 34ad85c34d8997e141ef940b2d77cb91 463 Pfam PF13347 MFS/sugar transport protein 16 437 1.7E-104 T 11-10-2018 UP12_09380 34ad85c34d8997e141ef940b2d77cb91 463 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 14 450 9.6E-151 T 11-10-2018 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 UP12_09380 34ad85c34d8997e141ef940b2d77cb91 463 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 65 90 - T 11-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 UP12_09380 34ad85c34d8997e141ef940b2d77cb91 463 SUPERFAMILY SSF103473 17 424 3.14E-40 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_10825 4968af295664b463f253d4715244f764 373 SUPERFAMILY SSF53187 5 369 1.81E-63 T 11-10-2018 UP12_10825 4968af295664b463f253d4715244f764 373 PIRSF PIRSF001123 82 180 2.5E-4 T 11-10-2018 IPR008007 Peptidase M42 UP12_10825 4968af295664b463f253d4715244f764 373 PIRSF PIRSF001123 4 100 2.3E-4 T 11-10-2018 IPR008007 Peptidase M42 UP12_10825 4968af295664b463f253d4715244f764 373 PIRSF PIRSF001123 257 373 7.6E-6 T 11-10-2018 IPR008007 Peptidase M42 UP12_10825 4968af295664b463f253d4715244f764 373 Pfam PF01546 Peptidase family M20/M25/M40 73 367 1.3E-24 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_10825 4968af295664b463f253d4715244f764 373 SUPERFAMILY SSF55031 179 284 4.71E-22 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_10825 4968af295664b463f253d4715244f764 373 Pfam PF07687 Peptidase dimerisation domain 180 273 8.1E-16 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain UP12_10825 4968af295664b463f253d4715244f764 373 Gene3D G3DSA:3.30.70.360 176 287 2.5E-133 T 11-10-2018 UP12_10825 4968af295664b463f253d4715244f764 373 Gene3D G3DSA:3.40.630.10 14 362 2.5E-133 T 11-10-2018 UP12_10825 4968af295664b463f253d4715244f764 373 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 367 1.8E-171 T 11-10-2018 IPR010162 Peptidase M20B, peptidase T-like UP12_10825 4968af295664b463f253d4715244f764 373 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Pfam PF13184 NusA-like KH domain 229 296 1.3E-28 T 11-10-2018 IPR025249 KH domain, NusA-like GO:0003723 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 SMART SM00316 133 199 1.5E-11 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Gene3D G3DSA:3.30.300.20 277 371 8.5E-32 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Pfam PF00575 S1 RNA binding domain 133 195 3.6E-12 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 341 5.8E-129 T 11-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Gene3D G3DSA:3.30.300.20 198 276 1.4E-33 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 SMART SM00322 300 370 0.62 T 11-10-2018 IPR004087 K Homology domain GO:0003676 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 SMART SM00322 229 292 0.7 T 11-10-2018 IPR004087 K Homology domain GO:0003676 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 SUPERFAMILY SSF54814 199 277 1.83E-30 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 SUPERFAMILY SSF50249 132 198 1.0E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 SUPERFAMILY SSF69705 1 126 2.62E-44 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 369 30.61 T 11-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 SUPERFAMILY SSF54814 278 341 3.86E-16 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Gene3D G3DSA:2.40.50.140 136 197 6.9E-25 T 11-10-2018 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Pfam PF08529 NusA N-terminal domain 4 123 7.3E-46 T 11-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 UP12_08115 6b474fa0bc66dff0b5d1c65c7d7bc72a 371 Gene3D G3DSA:3.30.1480.10 1 124 3.6E-51 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 UP12_19250 99cffafec021eb85bdb3b3b97040bd5b 240 ProDom PD942754 PLASMID TRANSMEMBRANE MEMBRANE PXO2-22/BXB0021/GBAA_PXO2_0021 9 229 6.0E-26 T 11-10-2018 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Gene3D G3DSA:3.90.600.10 325 422 4.6E-34 T 11-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Gene3D G3DSA:3.30.1490.20 119 188 2.2E-27 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 326 415 8.6E-27 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 43.002 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 11-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 SMART SM01210 325 417 9.0E-45 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 2.3E-83 T 11-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 SUPERFAMILY SSF51246 324 417 6.67E-28 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 SUPERFAMILY SSF56059 102 322 2.47E-62 T 11-10-2018 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 SMART SM01209 101 293 5.9E-129 T 11-10-2018 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 417 6.1E-176 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Gene3D G3DSA:3.30.470.20 189 324 2.3E-59 T 11-10-2018 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 SUPERFAMILY SSF52440 2 101 3.88E-34 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Gene3D G3DSA:3.40.50.20 1 93 1.3E-35 T 11-10-2018 UP12_03390 3678689dffaf07d49f67516210eeaeb6 424 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 8.8E-33 T 11-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 Gene3D G3DSA:3.30.420.40 134 300 2.3E-123 T 11-10-2018 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 136 148 1.2E-51 T 11-10-2018 IPR017861 Kae1/TsaD family UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 1.2E-51 T 11-10-2018 IPR017861 Kae1/TsaD family UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 1.2E-51 T 11-10-2018 IPR017861 Kae1/TsaD family UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 159 180 1.2E-51 T 11-10-2018 IPR017861 Kae1/TsaD family UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 269 278 1.2E-51 T 11-10-2018 IPR017861 Kae1/TsaD family UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 10 23 1.2E-51 T 11-10-2018 IPR017861 Kae1/TsaD family UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 7 338 64.173 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 SUPERFAMILY SSF53067 107 315 3.14E-45 T 11-10-2018 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 SUPERFAMILY SSF53067 9 128 1.34E-31 T 11-10-2018 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 Gene3D G3DSA:3.30.420.40 9 322 2.3E-123 T 11-10-2018 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 11-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 Pfam PF00814 Glycoprotease family 29 313 1.3E-105 T 11-10-2018 IPR000905 Gcp-like domain UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 9 320 6.9E-134 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 UP12_03140 59c1297038c034a19ebb0f4c051e47ef 342 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 10 313 1.1E-108 T 11-10-2018 IPR017861 Kae1/TsaD family UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 Pfam PF01266 FAD dependent oxidoreductase 34 378 2.6E-42 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 Pfam PF00355 Rieske [2Fe-2S] domain 429 504 1.6E-13 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 PRINTS PR00162 Rieske 2Fe-2S subunit signature 479 491 2.3E-8 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 PRINTS PR00162 Rieske 2Fe-2S subunit signature 458 469 2.3E-8 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 PRINTS PR00162 Rieske 2Fe-2S subunit signature 491 503 2.3E-8 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 Gene3D G3DSA:2.102.10.10 399 509 1.2E-24 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 Gene3D G3DSA:3.50.50.60 34 380 1.6E-47 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 SUPERFAMILY SSF51905 33 387 3.24E-32 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 Gene3D G3DSA:3.30.9.10 127 338 1.6E-47 T 11-10-2018 UP12_05225 904d4c59a3b6030f80b5eabf8bba8da0 510 SUPERFAMILY SSF50022 427 505 2.88E-25 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 2.1E-23 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 Gene3D G3DSA:3.30.1360.10 17 221 3.8E-89 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 1.8E-125 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 SMART SM00662 20 227 2.2E-103 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 152 1.9E-24 T 11-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 SUPERFAMILY SSF55257 5 230 1.16E-31 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 1.0E-25 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 1.9E-29 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 SUPERFAMILY SSF47789 247 313 7.85E-25 T 11-10-2018 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 Gene3D G3DSA:1.10.150.20 237 314 1.5E-34 T 11-10-2018 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 37.158 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 SUPERFAMILY SSF56553 50 171 1.31E-43 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00865 ef701b55ad23a747966f3a3ba69d6915 314 Gene3D G3DSA:2.170.120.12 50 170 3.8E-89 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_03680 52da991d441728904df47fe37934de52 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 2.6E-51 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 2.6E-51 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 2.6E-51 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 2.6E-51 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 2.6E-51 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 2.6E-51 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 2.6E-51 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 412 5.2E-51 T 11-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 UP12_03680 52da991d441728904df47fe37934de52 442 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 11-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 SUPERFAMILY SSF56327 173 439 5.46E-96 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_03680 52da991d441728904df47fe37934de52 442 Gene3D G3DSA:3.40.50.720 1 170 2.6E-71 T 11-10-2018 UP12_03680 52da991d441728904df47fe37934de52 442 SUPERFAMILY SSF51735 4 168 1.73E-56 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03680 52da991d441728904df47fe37934de52 442 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 2.6E-71 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03680 52da991d441728904df47fe37934de52 442 Gene3D G3DSA:3.90.110.10 171 442 3.8E-102 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_09230 f5be05e458c302bd7a8ff94aa44286c1 273 SUPERFAMILY SSF69618 7 268 3.79E-53 T 11-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_09230 f5be05e458c302bd7a8ff94aa44286c1 273 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 259 1.1E-36 T 11-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_09230 f5be05e458c302bd7a8ff94aa44286c1 273 Gene3D G3DSA:3.40.50.10090 38 174 2.9E-75 T 11-10-2018 UP12_09230 f5be05e458c302bd7a8ff94aa44286c1 273 Gene3D G3DSA:3.40.50.10090 14 258 2.9E-75 T 11-10-2018 UP12_17280 af7ec9dea9c5f47b61c0654b1c60a385 182 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 1 181 20.291 T 11-10-2018 IPR023522 Chromosome-anchoring protein RacA UP12_17280 af7ec9dea9c5f47b61c0654b1c60a385 182 Pfam PF13411 MerR HTH family regulatory protein 3 64 8.2E-13 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_17280 af7ec9dea9c5f47b61c0654b1c60a385 182 Gene3D G3DSA:1.10.1660.10 1 66 3.9E-21 T 11-10-2018 UP12_17280 af7ec9dea9c5f47b61c0654b1c60a385 182 SUPERFAMILY SSF46955 2 107 3.34E-10 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_09095 398e477d9237e4fb996452e62eb7c493 226 SMART SM00100 15 133 5.1E-7 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain UP12_09095 398e477d9237e4fb996452e62eb7c493 226 Pfam PF13545 Crp-like helix-turn-helix domain 154 218 4.7E-12 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 UP12_09095 398e477d9237e4fb996452e62eb7c493 226 SUPERFAMILY SSF51206 24 141 6.55E-24 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like UP12_09095 398e477d9237e4fb996452e62eb7c493 226 Pfam PF00027 Cyclic nucleotide-binding domain 35 116 8.0E-15 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain UP12_09095 398e477d9237e4fb996452e62eb7c493 226 SUPERFAMILY SSF46785 151 221 2.12E-11 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09095 398e477d9237e4fb996452e62eb7c493 226 Gene3D G3DSA:2.60.120.10 12 155 1.6E-19 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_09095 398e477d9237e4fb996452e62eb7c493 226 Gene3D G3DSA:1.10.10.10 156 224 1.3E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 Pfam PF00873 AcrB/AcrD/AcrF family 303 1061 6.8E-164 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 Pfam PF00873 AcrB/AcrD/AcrF family 4 244 8.3E-41 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 Gene3D G3DSA:1.20.1640.10 863 1074 8.3E-56 T 11-10-2018 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 Gene3D G3DSA:3.30.70.1430 41 135 4.1E-20 T 11-10-2018 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 SUPERFAMILY SSF82866 844 1067 3.79E-46 T 11-10-2018 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 SUPERFAMILY SSF82714 184 246 1.24E-5 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 Gene3D G3DSA:1.20.1640.10 359 559 3.1E-56 T 11-10-2018 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 SUPERFAMILY SSF82714 758 841 1.31E-14 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 SUPERFAMILY SSF82693 134 374 9.68E-15 T 11-10-2018 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 PRINTS PR00702 Acriflavin resistance protein family signature 594 611 1.1E-24 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 PRINTS PR00702 Acriflavin resistance protein family signature 517 540 1.1E-24 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.1E-24 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 PRINTS PR00702 Acriflavin resistance protein family signature 492 515 1.1E-24 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.1E-24 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 SUPERFAMILY SSF82693 41 132 1.26E-20 T 11-10-2018 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 SUPERFAMILY SSF82866 342 543 2.62E-44 T 11-10-2018 UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 Gene3D G3DSA:3.30.2090.10 181 320 3.1E-5 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UP12_03595 733daa1bd07a8e106196c90e421ef192 1074 Gene3D G3DSA:3.30.2090.10 756 843 2.6E-13 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UP12_14775 34295e104d53f8ecd5defe4b1d8165df 328 Gene3D G3DSA:1.10.287.70 11 108 9.8E-19 T 11-10-2018 UP12_14775 34295e104d53f8ecd5defe4b1d8165df 328 Pfam PF07885 Ion channel 22 97 2.1E-14 T 11-10-2018 IPR013099 Potassium channel domain UP12_14775 34295e104d53f8ecd5defe4b1d8165df 328 SUPERFAMILY SSF51735 113 254 4.49E-17 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_14775 34295e104d53f8ecd5defe4b1d8165df 328 Gene3D G3DSA:3.40.50.720 110 251 1.8E-25 T 11-10-2018 UP12_14775 34295e104d53f8ecd5defe4b1d8165df 328 SUPERFAMILY SSF81324 10 130 3.79E-23 T 11-10-2018 UP12_14775 34295e104d53f8ecd5defe4b1d8165df 328 Pfam PF02254 TrkA-N domain 118 238 8.6E-17 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UP12_16865 45337cff92730b86e366b86a21795ab1 393 TIGRFAM TIGR04012 poly_gGlu_PgsB: poly-gamma-glutamate synthase PgsB 2 383 4.0E-174 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 SUPERFAMILY SSF53623 33 235 1.01E-17 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_16865 45337cff92730b86e366b86a21795ab1 393 Pfam PF08245 Mur ligase middle domain 37 201 2.4E-9 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UP12_16865 45337cff92730b86e366b86a21795ab1 393 Gene3D G3DSA:3.40.1190.10 29 238 7.2E-17 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 111 126 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 196 213 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 57 74 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 140 155 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 162 179 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 258 275 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 293 308 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 362 378 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 34 50 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_16865 45337cff92730b86e366b86a21795ab1 393 PRINTS PR01758 Capsule biosynthesis protein CapB signature 77 95 8.0E-107 T 11-10-2018 IPR008337 Capsule biosynthesis protein CapB GO:0016020|GO:0045227 UP12_08850 1c8823d426e0e4343b010e04dd250056 206 SUPERFAMILY SSF52218 1 205 1.68E-43 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08850 1c8823d426e0e4343b010e04dd250056 206 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 203 25.07 T 11-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 UP12_08850 1c8823d426e0e4343b010e04dd250056 206 Gene3D G3DSA:3.40.50.360 1 206 3.8E-52 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08850 1c8823d426e0e4343b010e04dd250056 206 Pfam PF02525 Flavodoxin-like fold 3 201 8.4E-38 T 11-10-2018 IPR003680 Flavodoxin-like fold UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 489 889 2.4E-129 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:1.10.287.490 1160 1206 1.5E-60 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 SUPERFAMILY SSF52777 15 192 3.34E-43 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:3.30.559.30 194 445 1.1E-139 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Pfam PF00550 Phosphopantetheine attachment site 976 1040 8.6E-16 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Pfam PF13193 AMP-binding enzyme C-terminal domain 874 949 3.2E-11 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 SUPERFAMILY SSF53474 1054 1255 2.48E-30 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:3.40.50.980 472 778 6.7E-104 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 SUPERFAMILY SSF52777 193 453 1.07E-52 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 SUPERFAMILY SSF56801 427 986 9.42E-153 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:3.40.50.980 490 625 6.7E-104 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:1.10.1200.10 963 1048 9.2E-24 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Pfam PF00501 AMP-binding enzyme 468 866 1.3E-100 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 SMART SM00823 Phosphopantetheine attachment site 975 1044 0.0036 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:2.30.38.10 779 856 4.1E-31 T 11-10-2018 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:3.40.50.1820 1057 1264 1.5E-60 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Pfam PF00975 Thioesterase domain 1060 1251 1.4E-18 T 11-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 SUPERFAMILY SSF47336 970 1040 1.03E-18 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:3.30.559.10 15 380 1.1E-139 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Pfam PF00668 Condensation domain 9 448 4.2E-115 T 11-10-2018 IPR001242 Condensation domain UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 ProSitePatterns PS00455 Putative AMP-binding domain signature. 610 621 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02010 87a0f0187629870e257c40bd915ee3c1 1277 Gene3D G3DSA:3.30.300.30 860 961 2.2E-31 T 11-10-2018 UP12_04280 670e52e9c105dca376ee367437460bb5 195 Pfam PF00881 Nitroreductase family 18 174 3.2E-24 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UP12_04280 670e52e9c105dca376ee367437460bb5 195 PIRSF PIRSF000232 8 195 5.2E-48 T 11-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like UP12_04280 670e52e9c105dca376ee367437460bb5 195 SUPERFAMILY SSF55469 12 192 2.22E-36 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_04280 670e52e9c105dca376ee367437460bb5 195 Gene3D G3DSA:3.40.109.10 6 194 8.8E-42 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 SMART SM00257 54 98 4.0E-6 T 11-10-2018 IPR018392 LysM domain UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 SMART SM00257 5 49 4.2E-14 T 11-10-2018 IPR018392 LysM domain UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 Pfam PF01476 LysM domain 6 49 3.2E-13 T 11-10-2018 IPR018392 LysM domain UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 Pfam PF01476 LysM domain 55 88 9.0E-8 T 11-10-2018 IPR018392 LysM domain UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 SUPERFAMILY SSF54106 4 49 1.26E-11 T 11-10-2018 UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 Gene3D G3DSA:3.10.50.10 325 384 3.8E-104 T 11-10-2018 IPR029070 Chitinase insertion domain superfamily UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 Gene3D G3DSA:3.20.20.80 132 418 3.8E-104 T 11-10-2018 UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 SUPERFAMILY SSF51445 130 428 9.1E-46 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 Gene3D G3DSA:3.10.350.10 53 109 1.3E-8 T 11-10-2018 IPR036779 LysM domain superfamily UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 Gene3D G3DSA:3.10.350.10 2 52 1.4E-15 T 11-10-2018 IPR036779 LysM domain superfamily UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 SMART SM00636 105 413 1.5E-28 T 11-10-2018 IPR011583 Chitinase II GO:0008061 UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 Pfam PF00704 Glycosyl hydrolases family 18 178 411 1.2E-26 T 11-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 UP12_00120 7c3e5f9df0f1bdcbe2922c7f98628ccc 433 SUPERFAMILY SSF54106 53 98 1.57E-7 T 11-10-2018 UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 11-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 SUPERFAMILY SSF46785 5 76 2.8E-15 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 4.0E-15 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 SMART SM00420 6 58 1.3E-19 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 SMART SM01134 73 232 7.6E-69 T 11-10-2018 UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 Pfam PF00455 DeoR C terminal sensor domain 75 231 2.2E-50 T 11-10-2018 IPR014036 DeoR C-terminal sensor domain UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 SUPERFAMILY SSF100950 74 231 7.74E-34 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 7.7E-8 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_06965 16dc6f4be77a36b64dcec6aa3ae49313 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 7.7E-8 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_08640 45efd352a8ff2edeb5070e717d1008e5 236 Gene3D G3DSA:3.30.240.20 81 155 9.8E-24 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily UP12_08640 45efd352a8ff2edeb5070e717d1008e5 236 SUPERFAMILY SSF160704 106 170 4.71E-5 T 11-10-2018 IPR036699 YehR-like superfamily UP12_08640 45efd352a8ff2edeb5070e717d1008e5 236 Gene3D G3DSA:3.30.240.20 170 229 6.7E-16 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily UP12_08640 45efd352a8ff2edeb5070e717d1008e5 236 Pfam PF04239 Protein of unknown function (DUF421) 89 205 9.7E-31 T 11-10-2018 IPR007353 Protein of unknown function DUF421 UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 Pfam PF13083 KH domain 63 130 9.3E-11 T 11-10-2018 UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 SMART SM00393 126 206 9.7E-19 T 11-10-2018 IPR001374 R3H domain GO:0003676 UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 SUPERFAMILY SSF82708 147 205 3.3E-8 T 11-10-2018 IPR036867 R3H domain superfamily GO:0003676 UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 SMART SM01245 5 57 3.2E-19 T 11-10-2018 IPR032782 Jag, N-terminal UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 Gene3D G3DSA:3.30.1370.50 141 207 1.5E-20 T 11-10-2018 IPR036867 R3H domain superfamily GO:0003676 UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 Pfam PF14804 Jag N-terminus 8 54 2.6E-16 T 11-10-2018 IPR032782 Jag, N-terminal UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 Gene3D G3DSA:3.30.300.20 59 140 5.9E-20 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 Gene3D G3DSA:3.30.30.80 1 57 6.0E-16 T 11-10-2018 IPR038247 Jag, N-terminal domain superfamily UP12_19170 1a10b5ca791526d569e8a9f25bb4889f 207 Pfam PF01424 R3H domain 145 203 1.1E-15 T 11-10-2018 IPR001374 R3H domain GO:0003676 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 SMART SM00859 2 141 7.2E-46 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 141 2.2E-34 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 339 43.229 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 Gene3D G3DSA:3.40.50.720 2 331 8.8E-128 T 11-10-2018 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 11-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 SUPERFAMILY SSF51735 2 177 2.3E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 SUPERFAMILY SSF55347 149 313 4.13E-58 T 11-10-2018 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 Gene3D G3DSA:3.30.360.10 147 313 8.8E-128 T 11-10-2018 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 316 2.2E-33 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_05565 4535e411dbe4c73b92725c3cdb1ab7a0 345 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 345 1.7E-139 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 SUPERFAMILY SSF46458 1 144 4.16E-31 T 11-10-2018 IPR009050 Globin-like superfamily UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 Gene3D G3DSA:3.40.50.80 253 395 3.5E-26 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 SUPERFAMILY SSF52343 255 389 2.23E-24 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 Gene3D G3DSA:2.40.30.10 152 252 4.3E-32 T 11-10-2018 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 Pfam PF00970 Oxidoreductase FAD-binding domain 158 252 4.4E-7 T 11-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 PRINTS PR00410 Phenol hydroxylase reductase family signature 185 197 9.9E-8 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 PRINTS PR00410 Phenol hydroxylase reductase family signature 356 364 9.9E-8 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 PRINTS PR00410 Phenol hydroxylase reductase family signature 263 282 9.9E-8 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 PRINTS PR00410 Phenol hydroxylase reductase family signature 247 256 9.9E-8 T 11-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 Gene3D G3DSA:1.10.490.10 1 145 1.4E-44 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 Pfam PF00175 Oxidoreductase NAD-binding domain 264 367 4.7E-8 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 Pfam PF00042 Globin 7 102 2.4E-6 T 11-10-2018 IPR000971 Globin GO:0020037 UP12_04845 530c24b5ef06916bd2dabc0bc3219dc0 399 SUPERFAMILY SSF63380 151 254 7.66E-25 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 565 578 3.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 3.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 3.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 3.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 Gene3D G3DSA:1.10.287.130 348 428 2.3E-11 T 11-10-2018 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 SUPERFAMILY SSF55874 414 578 5.89E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 SMART SM00388 356 424 1.6E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 SMART SM00387 470 581 9.4E-32 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 SUPERFAMILY SSF47384 342 424 1.67E-13 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 357 420 5.4E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 579 2.4E-25 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15615 30a90f57de40e44d2cf6bfffc8257d84 584 Gene3D G3DSA:3.30.565.10 429 581 6.0E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_00085 766c73add04ea29c6f003e5a0f38f400 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 4.5E-160 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00085 766c73add04ea29c6f003e5a0f38f400 294 SUPERFAMILY SSF51366 18 269 8.47E-69 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_00085 766c73add04ea29c6f003e5a0f38f400 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00085 766c73add04ea29c6f003e5a0f38f400 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 53.831 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00085 766c73add04ea29c6f003e5a0f38f400 294 PIRSF PIRSF029271 1 294 4.6E-154 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00085 766c73add04ea29c6f003e5a0f38f400 294 Gene3D G3DSA:3.20.20.70 2 294 3.1E-149 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_00085 766c73add04ea29c6f003e5a0f38f400 294 Pfam PF01680 SOR/SNZ family 7 212 3.3E-107 T 11-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_16705 29aaded179394e001b9605ac16d1fb26 534 SMART SM00382 49 221 7.0E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16705 29aaded179394e001b9605ac16d1fb26 534 Pfam PF00005 ABC transporter 41 171 4.2E-18 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16705 29aaded179394e001b9605ac16d1fb26 534 Gene3D G3DSA:3.40.50.300 2 281 3.3E-44 T 11-10-2018 UP12_16705 29aaded179394e001b9605ac16d1fb26 534 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16705 29aaded179394e001b9605ac16d1fb26 534 SUPERFAMILY SSF52540 34 234 9.03E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05295 beccc04baef6344dcb56a81fd299c152 140 Gene3D G3DSA:1.10.10.10 14 81 9.0E-17 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05295 beccc04baef6344dcb56a81fd299c152 140 Pfam PF03965 Penicillinase repressor 18 130 1.5E-22 T 11-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 UP12_05295 beccc04baef6344dcb56a81fd299c152 140 SUPERFAMILY SSF46785 18 124 3.38E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06550 6af82fce05b3327e3080b731131da344 165 Gene3D G3DSA:1.10.10.10 77 161 1.2E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06550 6af82fce05b3327e3080b731131da344 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 159 40.156 T 11-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 UP12_06550 6af82fce05b3327e3080b731131da344 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 80 160 1.6E-29 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UP12_06550 6af82fce05b3327e3080b731131da344 165 SUPERFAMILY SSF46767 77 161 1.57E-29 T 11-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 UP12_06550 6af82fce05b3327e3080b731131da344 165 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 3 75 3.8E-13 T 11-10-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UP12_06550 6af82fce05b3327e3080b731131da344 165 Gene3D G3DSA:3.30.160.70 3 73 9.4E-18 T 11-10-2018 UP12_06550 6af82fce05b3327e3080b731131da344 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 158 1.1E-34 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UP12_06550 6af82fce05b3327e3080b731131da344 165 SUPERFAMILY SSF53155 3 83 2.75E-17 T 11-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UP12_06550 6af82fce05b3327e3080b731131da344 165 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 11-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 SUPERFAMILY SSF54001 157 280 2.68E-39 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 Pfam PF00877 NlpC/P60 family 40 149 2.9E-21 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 Pfam PF00877 NlpC/P60 family 171 277 3.8E-29 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 Pfam PF00877 NlpC/P60 family 301 402 4.4E-18 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 Gene3D G3DSA:3.90.1720.10 282 407 2.1E-31 T 11-10-2018 UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 Gene3D G3DSA:3.90.1720.10 19 152 6.0E-36 T 11-10-2018 UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 Gene3D G3DSA:3.90.1720.10 155 281 4.7E-44 T 11-10-2018 UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 SUPERFAMILY SSF54001 288 406 1.23E-28 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_16850 316b5ede3a277703070b19f6cc5b073f 407 SUPERFAMILY SSF54001 31 153 4.27E-33 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_12270 b9888fc7066e1723bae4e6318e1dabd1 227 Gene3D G3DSA:2.160.20.70 102 225 1.0E-36 T 11-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 UP12_12270 b9888fc7066e1723bae4e6318e1dabd1 227 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 210 6.0E-41 T 11-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 UP12_12270 b9888fc7066e1723bae4e6318e1dabd1 227 Gene3D G3DSA:3.30.160.540 7 88 2.8E-26 T 11-10-2018 UP12_12270 b9888fc7066e1723bae4e6318e1dabd1 227 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 8 211 21.716 T 11-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 UP12_12270 b9888fc7066e1723bae4e6318e1dabd1 227 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 109 206 2.2E-31 T 11-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 UP12_12270 b9888fc7066e1723bae4e6318e1dabd1 227 SUPERFAMILY SSF63848 108 211 1.27E-29 T 11-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 Gene3D G3DSA:3.40.50.970 348 568 5.0E-60 T 11-10-2018 UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 526 1.4E-42 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 Gene3D G3DSA:3.40.50.1220 183 335 8.6E-51 T 11-10-2018 UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 SUPERFAMILY SSF52518 358 562 7.33E-61 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 SUPERFAMILY SSF52467 187 349 1.29E-47 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 Gene3D G3DSA:3.40.50.970 2 182 9.5E-57 T 11-10-2018 UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 417 436 - T 11-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 SUPERFAMILY SSF52518 4 177 2.33E-41 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 171 8.1E-43 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UP12_02390 4ed4119d344d74ae3037f379e268a5b2 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 321 6.3E-37 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 Gene3D G3DSA:3.40.50.300 299 550 1.5E-64 T 11-10-2018 UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 SUPERFAMILY SSF52540 4 237 1.24E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 Pfam PF00005 ABC transporter 319 465 1.8E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 Pfam PF00005 ABC transporter 23 173 5.0E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 SUPERFAMILY SSF52540 292 527 6.32E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 SMART SM00382 328 513 8.6E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 SMART SM00382 32 224 1.1E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 Gene3D G3DSA:3.40.50.300 3 257 1.4E-68 T 11-10-2018 UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 ProSitePatterns PS00211 ABC transporters family signature. 437 451 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18840 f74d15a15c668ad8a33de4604f86426e 571 Pfam PF12558 ATP-binding cassette cobalt transporter 237 310 1.8E-19 T 11-10-2018 IPR022216 Putative ABC cobalt transporter UP12_01650 1a73822cad5efea9272d7416f74acd5e 396 Gene3D G3DSA:3.20.20.60 35 232 1.4E-7 T 11-10-2018 UP12_01650 1a73822cad5efea9272d7416f74acd5e 396 Gene3D G3DSA:3.20.20.60 256 374 1.2E-10 T 11-10-2018 UP12_01650 1a73822cad5efea9272d7416f74acd5e 396 SUPERFAMILY SSF51621 35 315 3.14E-23 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UP12_01650 1a73822cad5efea9272d7416f74acd5e 396 Pfam PF15617 C-C_Bond_Lyase of the TIM-Barrel fold 31 369 7.2E-128 T 11-10-2018 IPR039480 C-C bond lyase-like UP12_15800 41b9c23ea50c364fb1bedeab5f0ff81d 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 119 2.0E-56 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 UP12_15800 41b9c23ea50c364fb1bedeab5f0ff81d 156 Pfam PF01668 SmpB protein 10 150 5.5E-64 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 UP12_15800 41b9c23ea50c364fb1bedeab5f0ff81d 156 Gene3D G3DSA:2.40.280.10 3 129 4.4E-52 T 11-10-2018 IPR023620 Small protein B UP12_15800 41b9c23ea50c364fb1bedeab5f0ff81d 156 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 11-10-2018 IPR020081 SsrA-binding protein, conserved site UP12_15800 41b9c23ea50c364fb1bedeab5f0ff81d 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 1.9E-61 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 UP12_15800 41b9c23ea50c364fb1bedeab5f0ff81d 156 SUPERFAMILY SSF74982 4 132 1.83E-54 T 11-10-2018 IPR023620 Small protein B UP12_15800 41b9c23ea50c364fb1bedeab5f0ff81d 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 78.456 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 UP12_03360 e75861ac56a65f63c888b3a95a706a71 227 SMART SM01211 1 219 8.8E-136 T 11-10-2018 UP12_03360 e75861ac56a65f63c888b3a95a706a71 227 Gene3D G3DSA:3.40.50.880 1 220 1.9E-71 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_03360 e75861ac56a65f63c888b3a95a706a71 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 205 1.7E-43 T 11-10-2018 UP12_03360 e75861ac56a65f63c888b3a95a706a71 227 PIRSF PIRSF001586 1 222 8.8E-86 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03360 e75861ac56a65f63c888b3a95a706a71 227 SUPERFAMILY SSF52317 2 219 4.45E-77 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_03360 e75861ac56a65f63c888b3a95a706a71 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 217 43.732 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03360 e75861ac56a65f63c888b3a95a706a71 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 218 1.7E-91 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 SUPERFAMILY SSF54814 2 105 6.28E-39 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 8.6E-40 T 11-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 Gene3D G3DSA:3.30.300.20 17 106 3.3E-33 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 11-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 Pfam PF07650 KH domain 37 109 1.7E-21 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 SMART SM00322 59 124 7.5E-9 T 11-10-2018 IPR004087 K Homology domain GO:0003676 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 Gene3D G3DSA:3.30.1140.32 107 207 6.7E-41 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.9E-96 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.485 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 UP12_00755 5d41e758db23dafd48dbdb25cabe6854 218 SUPERFAMILY SSF54821 107 205 1.57E-38 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 Gene3D G3DSA:3.30.70.1400 51 137 8.3E-92 T 11-10-2018 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 Gene3D G3DSA:4.10.1250.10 238 280 8.6E-18 T 11-10-2018 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 363 48.7 T 11-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 SUPERFAMILY SSF101790 274 363 1.13E-25 T 11-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 PIRSF PIRSF006487 1 365 2.4E-108 T 11-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 258 2.6E-94 T 11-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 267 357 2.2E-27 T 11-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 Gene3D G3DSA:2.40.30.110 281 363 3.0E-31 T 11-10-2018 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 Gene3D G3DSA:3.30.1360.120 4 236 8.3E-92 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 363 7.5E-154 T 11-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 UP12_11115 16d8067c933eb498be6c3a55bd8208fa 365 SUPERFAMILY SSF103025 2 282 4.71E-100 T 11-10-2018 UP12_00435 7da9e1631f1aa73b4b3797d7395b4c77 302 SUPERFAMILY SSF109998 45 189 1.53E-22 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily UP12_00435 7da9e1631f1aa73b4b3797d7395b4c77 302 Gene3D G3DSA:3.10.50.40 161 254 7.9E-30 T 11-10-2018 UP12_00435 7da9e1631f1aa73b4b3797d7395b4c77 302 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 189 210 - T 11-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 UP12_00435 7da9e1631f1aa73b4b3797d7395b4c77 302 Pfam PF13145 PPIC-type PPIASE domain 141 267 1.2E-19 T 11-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 UP12_00435 7da9e1631f1aa73b4b3797d7395b4c77 302 SUPERFAMILY SSF54534 153 252 1.18E-18 T 11-10-2018 UP12_00435 7da9e1631f1aa73b4b3797d7395b4c77 302 Gene3D G3DSA:1.10.4030.30 20 160 7.9E-30 T 11-10-2018 UP12_00435 7da9e1631f1aa73b4b3797d7395b4c77 302 Pfam PF13624 SurA N-terminal domain 67 128 1.6E-6 T 11-10-2018 UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 SUPERFAMILY SSF88659 98 166 7.85E-13 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 165 5.2E-31 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 Pfam PF08281 Sigma-70, region 4 110 159 1.5E-9 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 Gene3D G3DSA:1.10.10.10 90 167 1.7E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 61 - T 11-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 Gene3D G3DSA:1.10.1740.10 1 71 1.2E-24 T 11-10-2018 UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 Pfam PF04542 Sigma-70 region 2 9 74 1.1E-16 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_10390 fc56ac48345c89334c0b4131f3f6bd3f 202 SUPERFAMILY SSF88946 3 90 1.61E-22 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Pfam PF02355 Protein export membrane protein 240 405 9.1E-14 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Pfam PF02355 Protein export membrane protein 550 726 1.4E-66 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 33 404 1.5E-115 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 475 718 6.6E-69 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Gene3D G3DSA:3.30.70.3400 33 121 7.6E-21 T 11-10-2018 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 181 397 1.8E-57 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 553 715 2.1E-50 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 419 33.733 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 PRINTS PR01755 Bacterial translocase SecF protein signature 473 488 1.2E-24 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 PRINTS PR01755 Bacterial translocase SecF protein signature 631 649 1.2E-24 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 PRINTS PR01755 Bacterial translocase SecF protein signature 666 681 1.2E-24 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 PRINTS PR01755 Bacterial translocase SecF protein signature 583 597 1.2E-24 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Gene3D G3DSA:1.20.1640.10 224 421 5.3E-14 T 11-10-2018 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Pfam PF07549 SecD/SecF GG Motif 469 492 0.0063 T 11-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 SUPERFAMILY SSF82866 552 731 1.14E-32 T 11-10-2018 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 SUPERFAMILY SSF82866 214 408 6.54E-41 T 11-10-2018 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 446 729 25.044 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 UP12_12105 4ea1d8359cbcba8d8a223e97a02a37e6 742 Gene3D G3DSA:1.20.1640.10 551 742 1.8E-6 T 11-10-2018 UP12_06575 3ef234559d18099a76c065e1552a20be 231 SUPERFAMILY SSF56784 1 221 1.13E-54 T 11-10-2018 IPR036412 HAD-like superfamily UP12_06575 3ef234559d18099a76c065e1552a20be 231 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 178 3.7E-38 T 11-10-2018 UP12_06575 3ef234559d18099a76c065e1552a20be 231 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 2 216 50.35 T 11-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 UP12_06575 3ef234559d18099a76c065e1552a20be 231 Gene3D G3DSA:3.40.50.1000 6 209 1.2E-68 T 11-10-2018 IPR023214 HAD superfamily UP12_06575 3ef234559d18099a76c065e1552a20be 231 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 6 218 5.8E-105 T 11-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 UP12_06575 3ef234559d18099a76c065e1552a20be 231 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 3 186 3.0E-55 T 11-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 UP12_06575 3ef234559d18099a76c065e1552a20be 231 Pfam PF12710 haloacid dehalogenase-like hydrolase 6 177 5.3E-16 T 11-10-2018 UP12_06575 3ef234559d18099a76c065e1552a20be 231 Gene3D G3DSA:3.90.1470.20 15 134 1.2E-68 T 11-10-2018 UP12_11670 7c87fec42697de6721b98bef1d6b58bf 173 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 29 139 2.0E-23 T 11-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 UP12_11670 7c87fec42697de6721b98bef1d6b58bf 173 Gene3D G3DSA:3.40.50.1000 18 152 1.2E-22 T 11-10-2018 IPR023214 HAD superfamily UP12_11670 7c87fec42697de6721b98bef1d6b58bf 173 SUPERFAMILY SSF56784 2 151 1.26E-23 T 11-10-2018 IPR036412 HAD-like superfamily UP12_11670 7c87fec42697de6721b98bef1d6b58bf 173 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 39 131 2.4E-6 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UP12_11670 7c87fec42697de6721b98bef1d6b58bf 173 Pfam PF13419 Haloacid dehalogenase-like hydrolase 25 137 4.7E-10 T 11-10-2018 UP12_11670 7c87fec42697de6721b98bef1d6b58bf 173 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 4 169 4.2E-62 T 11-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like UP12_09340 0ec823b696012117234e7c19567c8c82 265 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 211 233 - T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_09340 0ec823b696012117234e7c19567c8c82 265 SUPERFAMILY SSF48179 150 258 1.05E-32 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_09340 0ec823b696012117234e7c19567c8c82 265 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 1 88 9.2E-11 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UP12_09340 0ec823b696012117234e7c19567c8c82 265 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 151 254 1.2E-34 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_09340 0ec823b696012117234e7c19567c8c82 265 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 1 255 1.2E-77 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_09340 0ec823b696012117234e7c19567c8c82 265 SUPERFAMILY SSF51735 1 148 7.22E-20 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_09340 0ec823b696012117234e7c19567c8c82 265 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 255 22.926 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_09340 0ec823b696012117234e7c19567c8c82 265 Gene3D G3DSA:1.10.3730.10 153 260 1.6E-37 T 11-10-2018 UP12_09340 0ec823b696012117234e7c19567c8c82 265 Gene3D G3DSA:3.40.50.720 1 152 7.0E-36 T 11-10-2018 UP12_09340 0ec823b696012117234e7c19567c8c82 265 PIRSF PIRSF000193 1 258 1.6E-71 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF00501 AMP-binding enzyme 1875 2272 1.8E-99 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF00501 AMP-binding enzyme 220 645 9.3E-60 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02020 e1648209ca86086c812a84980a701459 2731 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1006 1196 3.2E-19 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.40.50.1820 2461 2731 2.9E-37 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF53474 2453 2728 1.5E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.30.300.30 640 746 4.0E-34 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1352 1367 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.30.300.30 12 105 2.8E-7 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:1.10.1200.10 2367 2450 6.5E-21 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.30.300.30 2266 2366 2.4E-30 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF13193 AMP-binding enzyme C-terminal domain 2280 2352 4.2E-9 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.30.559.30 1598 1839 1.6E-130 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF47336 2373 2443 6.54E-16 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.30.559.10 1421 1785 1.6E-130 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF47336 1323 1393 1.7E-15 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02020 e1648209ca86086c812a84980a701459 2731 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2403 2418 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF56801 12 104 3.53E-6 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.40.50.720 759 1259 3.5E-80 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF51735 767 990 1.65E-21 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF52777 1599 1843 9.12E-62 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 SMART SM00824 Thioesterase 2474 2729 0.0058 T 11-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UP12_02020 e1648209ca86086c812a84980a701459 2731 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2016 2027 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF00975 Thioesterase domain 2473 2726 5.5E-21 T 11-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF00550 Phosphopantetheine attachment site 2380 2443 7.9E-12 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF00550 Phosphopantetheine attachment site 1330 1393 1.3E-10 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF56801 1834 2392 7.98E-148 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF51735 1007 1202 1.91E-27 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.40.50.12780 1866 2264 8.1E-135 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF52777 1418 1594 9.45E-39 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF08659 KR domain 1006 1194 3.9E-32 T 11-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02020 e1648209ca86086c812a84980a701459 2731 Pfam PF00668 Condensation domain 1413 1855 1.3E-112 T 11-10-2018 IPR001242 Condensation domain UP12_02020 e1648209ca86086c812a84980a701459 2731 SUPERFAMILY SSF56801 182 749 4.84E-90 T 11-10-2018 UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.40.50.1820 1318 1420 7.7E-21 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02020 e1648209ca86086c812a84980a701459 2731 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1896 2296 1.3E-128 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02020 e1648209ca86086c812a84980a701459 2731 Gene3D G3DSA:3.40.50.12780 188 639 1.3E-116 T 11-10-2018 UP12_07445 74703e796a031c5fd408f7f6cdbd216e 414 SUPERFAMILY SSF51735 16 136 7.79E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_07445 74703e796a031c5fd408f7f6cdbd216e 414 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 17 113 5.2E-8 T 11-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_07445 74703e796a031c5fd408f7f6cdbd216e 414 Gene3D G3DSA:3.40.50.720 10 160 3.4E-19 T 11-10-2018 UP12_07445 74703e796a031c5fd408f7f6cdbd216e 414 Pfam PF08666 SAF domain 329 394 6.3E-8 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UP12_07445 74703e796a031c5fd408f7f6cdbd216e 414 SMART SM00858 328 394 1.1E-4 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 44.564 T 11-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 2.8E-65 T 11-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 327 1.6E-147 T 11-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 SUPERFAMILY SSF51735 3 182 5.64E-72 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 3.6E-76 T 11-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 Gene3D G3DSA:1.10.3730.40 182 337 1.7E-69 T 11-10-2018 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 SUPERFAMILY SSF48179 183 331 1.87E-70 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 Gene3D G3DSA:3.40.50.720 1 181 3.2E-77 T 11-10-2018 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 PIRSF PIRSF000116 5 206 2.1E-41 T 11-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UP12_12420 96576bcf6b94e326551fd7edbbebdc3a 342 PIRSF PIRSF000116 201 332 5.1E-16 T 11-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 UP12_03060 b261ba5f4310ab32aaaec02f5cda923f 106 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 103 5.9E-22 T 11-10-2018 IPR008407 Branched-chain amino acid transport, AzlD UP12_12300 6e258bb291876a80b1741ee20016b6bf 337 Gene3D G3DSA:3.30.70.1070 184 251 4.7E-5 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 UP12_12300 6e258bb291876a80b1741ee20016b6bf 337 Pfam PF05036 Sporulation related domain 184 232 1.7E-5 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 Gene3D G3DSA:3.30.1330.90 13 136 4.4E-20 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 SUPERFAMILY SSF55021 137 218 4.2E-16 T 11-10-2018 UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 Pfam PF01842 ACT domain 149 210 1.2E-10 T 11-10-2018 IPR002912 ACT domain UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 Pfam PF03315 Serine dehydratase beta chain 5 72 1.5E-10 T 11-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 1 205 2.5E-104 T 11-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 PIRSF PIRSF036692 1 220 4.5E-102 T 11-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 SUPERFAMILY SSF143548 19 137 1.7E-30 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 UP12_07720 2a7b8e98169cb56d689d18a0affc7b0d 220 Gene3D G3DSA:3.30.70.260 139 217 1.5E-13 T 11-10-2018 UP12_15120 5cdd72d0acbc735062fdb7cc8f2a1238 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 1.1E-6 T 11-10-2018 UP12_15120 5cdd72d0acbc735062fdb7cc8f2a1238 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-6 T 11-10-2018 UP12_15120 5cdd72d0acbc735062fdb7cc8f2a1238 403 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.1E-6 T 11-10-2018 UP12_15120 5cdd72d0acbc735062fdb7cc8f2a1238 403 SUPERFAMILY SSF51905 149 337 3.26E-24 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_15120 5cdd72d0acbc735062fdb7cc8f2a1238 403 Gene3D G3DSA:3.50.50.100 1 403 5.1E-146 T 11-10-2018 UP12_15120 5cdd72d0acbc735062fdb7cc8f2a1238 403 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 324 8.8E-48 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_15120 5cdd72d0acbc735062fdb7cc8f2a1238 403 SUPERFAMILY SSF51905 3 209 9.26E-30 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05210 87197e53592f2fba63a66478b53269cc 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 129 148 5.7E-22 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_05210 87197e53592f2fba63a66478b53269cc 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 179 5.7E-22 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_05210 87197e53592f2fba63a66478b53269cc 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 324 340 5.7E-22 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_05210 87197e53592f2fba63a66478b53269cc 381 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 325 335 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_05210 87197e53592f2fba63a66478b53269cc 381 Pfam PF05922 Peptidase inhibitor I9 41 104 1.9E-5 T 11-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UP12_05210 87197e53592f2fba63a66478b53269cc 381 Pfam PF00082 Subtilase family 129 372 1.8E-58 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_05210 87197e53592f2fba63a66478b53269cc 381 SUPERFAMILY SSF54897 38 105 4.19E-20 T 11-10-2018 UP12_05210 87197e53592f2fba63a66478b53269cc 381 Gene3D G3DSA:3.30.70.80 32 108 8.7E-23 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UP12_05210 87197e53592f2fba63a66478b53269cc 381 SUPERFAMILY SSF52743 107 379 4.45E-89 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_05210 87197e53592f2fba63a66478b53269cc 381 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 134 145 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UP12_05210 87197e53592f2fba63a66478b53269cc 381 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 170 180 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_05210 87197e53592f2fba63a66478b53269cc 381 Gene3D G3DSA:3.40.50.200 109 381 1.5E-106 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 662 3.7E-275 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Gene3D G3DSA:2.40.50.140 314 386 3.8E-29 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SMART SM00278 539 558 2.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SMART SM00278 475 494 2.2 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SMART SM00278 441 460 240.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Pfam PF14520 Helix-hairpin-helix domain 443 493 0.0016 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Pfam PF12826 Helix-hairpin-helix motif 505 567 6.9E-24 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SUPERFAMILY SSF47781 399 580 1.63E-65 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SUPERFAMILY SSF56091 2 312 2.26E-121 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Gene3D G3DSA:1.10.287.610 1 72 3.7E-25 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Gene3D G3DSA:3.40.50.10190 580 667 6.0E-26 T 11-10-2018 IPR036420 BRCT domain superfamily UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 PIRSF PIRSF001604 1 668 3.7E-259 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Hamap MF_01588 DNA ligase [ligA]. 4 666 53.604 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Gene3D G3DSA:1.10.150.20 427 499 1.2E-30 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 327 342 - T 11-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Gene3D G3DSA:1.10.150.20 500 579 3.1E-26 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SUPERFAMILY SSF52113 590 665 1.07E-18 T 11-10-2018 IPR036420 BRCT domain superfamily UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 593 662 1.1E-12 T 11-10-2018 IPR001357 BRCT domain UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 318 394 5.9E-33 T 11-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 403 429 4.1E-10 T 11-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 11-10-2018 IPR018239 NAD-dependent DNA ligase, active site UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SUPERFAMILY SSF50249 313 397 2.06E-26 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 314 1.1E-129 T 11-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Gene3D G3DSA:2.20.70.80 387 424 3.4E-12 T 11-10-2018 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SMART SM00532 5 443 4.3E-281 T 11-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 SMART SM00292 592 668 8.7E-12 T 11-10-2018 IPR001357 BRCT domain UP12_03475 29b35d9347e21412861ce5ba425dbf3a 668 Gene3D G3DSA:3.30.470.90 73 313 2.3E-102 T 11-10-2018 UP12_07290 357957be0db80e04b77131d3e084e216 259 Gene3D G3DSA:3.40.1090.10 1 97 2.7E-25 T 11-10-2018 UP12_07290 357957be0db80e04b77131d3e084e216 259 ProSitePatterns PS01237 Uncharacterized protein family UPF0028 signature. 11 43 - T 11-10-2018 IPR001423 Lysophospholipase patatin, conserved site GO:0004622|GO:0046470 Reactome: R-HSA-6814848 UP12_07290 357957be0db80e04b77131d3e084e216 259 Gene3D G3DSA:3.40.1090.20 98 199 3.5E-5 T 11-10-2018 UP12_07290 357957be0db80e04b77131d3e084e216 259 SUPERFAMILY SSF52151 1 242 1.23E-54 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_07290 357957be0db80e04b77131d3e084e216 259 Pfam PF01734 Patatin-like phospholipase 8 69 6.1E-13 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 UP12_07290 357957be0db80e04b77131d3e084e216 259 Pfam PF01734 Patatin-like phospholipase 124 164 2.9E-9 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 UP12_05040 186609c6bb6f874da532ba8bdbb4cfdc 404 PIRSF PIRSF033091 1 404 4.4E-136 T 11-10-2018 IPR014576 Predicted phosphoesterase, YhaO type UP12_05040 186609c6bb6f874da532ba8bdbb4cfdc 404 SUPERFAMILY SSF56300 5 302 1.52E-50 T 11-10-2018 UP12_05040 186609c6bb6f874da532ba8bdbb4cfdc 404 Pfam PF00149 Calcineurin-like phosphoesterase 4 202 5.6E-14 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_05040 186609c6bb6f874da532ba8bdbb4cfdc 404 Gene3D G3DSA:3.60.21.10 2 253 9.0E-54 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 PRINTS PR01607 Apyrase family signature 654 671 3.8E-24 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 PRINTS PR01607 Apyrase family signature 461 479 3.8E-24 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 PRINTS PR01607 Apyrase family signature 708 728 3.8E-24 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 PRINTS PR01607 Apyrase family signature 825 848 3.8E-24 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 PRINTS PR01607 Apyrase family signature 682 705 3.8E-24 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 PRINTS PR01607 Apyrase family signature 893 912 3.8E-24 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 SUPERFAMILY SSF50199 249 396 3.92E-29 T 11-10-2018 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 Gene3D G3DSA:2.40.50.90 246 395 7.4E-35 T 11-10-2018 IPR035437 SNase-like, OB-fold superfamily UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 Pfam PF00149 Calcineurin-like phosphoesterase 464 699 9.1E-12 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 SUPERFAMILY SSF56300 457 771 3.4E-75 T 11-10-2018 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 ProSitePatterns PS00786 5'-nucleotidase signature 2. 545 556 - T 11-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 Pfam PF00565 Staphylococcal nuclease homologue 277 392 1.1E-23 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 SUPERFAMILY SSF55816 773 953 6.67E-41 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 Gene3D G3DSA:3.90.780.10 773 961 4.3E-40 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 Pfam PF02872 5'-nucleotidase, C-terminal domain 774 912 5.5E-31 T 11-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 Gene3D G3DSA:3.60.21.10 460 772 7.5E-82 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_04735 2775a6c10a242577f433b9f5fbffb5d2 967 SMART SM00318 251 392 1.4E-38 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 SUPERFAMILY SSF50037 280 324 1.88E-5 T 11-10-2018 IPR008988 Transcriptional repressor, C-terminal UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 Pfam PF03099 Biotin/lipoate A/B protein ligase family 104 214 1.1E-17 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 Gene3D G3DSA:1.10.10.10 2 65 1.1E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 86 323 9.0E-73 T 11-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 325 36.757 T 11-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 SUPERFAMILY SSF46785 6 62 4.84E-10 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 SUPERFAMILY SSF55681 72 276 2.9E-61 T 11-10-2018 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 9 77 2.4E-20 T 11-10-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 Gene3D G3DSA:3.30.930.10 75 278 1.6E-66 T 11-10-2018 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 Pfam PF08279 HTH domain 7 60 2.4E-15 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 Gene3D G3DSA:2.30.30.100 280 327 8.4E-8 T 11-10-2018 UP12_10060 25233e7dfc15c52e74348d2d4cf22195 327 Pfam PF02237 Biotin protein ligase C terminal domain 279 323 2.7E-10 T 11-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 Pfam PF01676 Metalloenzyme superfamily 7 380 2.9E-46 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 Gene3D G3DSA:3.40.720.10 7 390 2.4E-175 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 SUPERFAMILY SSF53649 5 393 1.23E-77 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 TIGRFAM TIGR01696 deoB: phosphopentomutase 8 388 3.6E-209 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 Hamap MF_00740 Phosphopentomutase [deoB]. 6 390 55.958 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 Gene3D G3DSA:3.30.70.1250 101 219 2.4E-175 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 PIRSF PIRSF001491 5 394 6.6E-168 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 UP12_10575 ae7b65413cb15ca4aed8b9776d520fa4 394 SUPERFAMILY SSF143856 103 219 4.84E-52 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 SUPERFAMILY SSF88946 8 98 7.38E-30 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 SUPERFAMILY SSF88659 117 185 1.14E-17 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 45 76 - T 11-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 184 4.2E-36 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 Pfam PF04542 Sigma-70 region 2 24 89 1.7E-22 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 187 4.4E-109 T 11-10-2018 IPR014294 RNA polymerase sigma-W, bacillaceae UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 Gene3D G3DSA:1.10.10.10 121 187 3.0E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 Gene3D G3DSA:1.10.1740.10 5 110 7.6E-32 T 11-10-2018 UP12_01055 9955f2320664cd9864a1dcccc4e09650 187 Pfam PF08281 Sigma-70, region 4 130 180 3.2E-17 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_16505 3d0b014c907d0b4988d5040838a0379e 187 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 128 182 1.7E-29 T 11-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal UP12_16505 3d0b014c907d0b4988d5040838a0379e 187 Gene3D G3DSA:3.30.505.50 140 186 3.3E-27 T 11-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily UP12_16505 3d0b014c907d0b4988d5040838a0379e 187 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 95 3.9E-29 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 UP12_16505 3d0b014c907d0b4988d5040838a0379e 187 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 186 24.857 T 11-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid UP12_16505 3d0b014c907d0b4988d5040838a0379e 187 Gene3D G3DSA:3.30.160.100 1 109 1.5E-29 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like UP12_16505 3d0b014c907d0b4988d5040838a0379e 187 SUPERFAMILY SSF69754 2 108 1.26E-31 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like UP12_16505 3d0b014c907d0b4988d5040838a0379e 187 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 6.8E-35 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 UP12_06980 eab111b87ac15e56494b688445b21713 201 Pfam PF00717 Peptidase S24-like 54 123 5.2E-20 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C UP12_06980 eab111b87ac15e56494b688445b21713 201 Gene3D G3DSA:2.10.109.10 77 201 1.7E-37 T 11-10-2018 UP12_06980 eab111b87ac15e56494b688445b21713 201 SUPERFAMILY SSF51306 45 198 1.09E-51 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily UP12_06980 eab111b87ac15e56494b688445b21713 201 ProSitePatterns PS00761 Signal peptidases I signature 3. 158 171 - T 11-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 UP12_06980 eab111b87ac15e56494b688445b21713 201 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 30 194 1.2E-55 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_06980 eab111b87ac15e56494b688445b21713 201 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 153 172 1.9E-25 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_06980 eab111b87ac15e56494b688445b21713 201 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 99 111 1.9E-25 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_06980 eab111b87ac15e56494b688445b21713 201 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 47 63 1.9E-25 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_06980 eab111b87ac15e56494b688445b21713 201 ProSitePatterns PS00760 Signal peptidases I lysine active site. 101 113 - T 11-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 UP12_06980 eab111b87ac15e56494b688445b21713 201 ProSitePatterns PS00501 Signal peptidases I serine active site. 56 63 - T 11-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 Pfam PF00171 Aldehyde dehydrogenase family 10 292 1.5E-17 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 Gene3D G3DSA:3.40.605.10 23 416 4.3E-165 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 18 411 2.3E-163 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 10 421 41.43 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 328 349 - T 11-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 PIRSF PIRSF000151 3 422 5.0E-178 T 11-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 Gene3D G3DSA:3.40.309.10 231 379 4.3E-165 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_09330 ae85e270dff54b0e04fa9725f6f2f1db 422 SUPERFAMILY SSF53720 10 421 4.06E-113 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.7E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.7E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.7E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 SUPERFAMILY SSF52172 1 127 5.98E-23 T 11-10-2018 IPR011006 CheY-like superfamily UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 SUPERFAMILY SSF46894 144 209 1.29E-16 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 SMART SM00448 2 116 1.6E-16 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 4.8E-18 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 SMART SM00421 150 207 1.4E-18 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 Pfam PF00072 Response regulator receiver domain 4 116 1.4E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_14960 08fca87781dd5c5b053d8e6054319b2e 213 Gene3D G3DSA:3.40.50.12740 3 212 3.2E-46 T 11-10-2018 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 Pfam PF00119 ATP synthase A chain 20 237 4.8E-59 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 PRINTS PR00123 ATP synthase A subunit signature 78 94 1.2E-18 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 PRINTS PR00123 ATP synthase A subunit signature 146 161 1.2E-18 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 PRINTS PR00123 ATP synthase A subunit signature 223 238 1.2E-18 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 PRINTS PR00123 ATP synthase A subunit signature 162 184 1.2E-18 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 11-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 SUPERFAMILY SSF81336 72 237 5.1E-42 T 11-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 11 239 3.1E-53 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 Gene3D G3DSA:1.20.120.220 70 244 2.8E-42 T 11-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17210 ba5536e2c7be5098657009f2bf149457 244 Hamap MF_01393 ATP synthase subunit a [atpB]. 8 243 14.176 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_03305 70ceda0ca1a17699acd4867b6383fb9b 395 Pfam PF07690 Major Facilitator Superfamily 13 316 1.0E-40 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_03305 70ceda0ca1a17699acd4867b6383fb9b 395 Gene3D G3DSA:1.20.1250.20 6 187 3.3E-30 T 11-10-2018 UP12_03305 70ceda0ca1a17699acd4867b6383fb9b 395 SUPERFAMILY SSF103473 8 384 1.14E-60 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_03305 70ceda0ca1a17699acd4867b6383fb9b 395 Gene3D G3DSA:1.20.1250.20 199 391 3.6E-18 T 11-10-2018 UP12_01400 573c904726abca477d3ac41c9f73ef3d 138 Pfam PF12120 Rifampin ADP-ribosyl transferase 13 110 1.8E-46 T 11-10-2018 IPR021975 Rifampin ADP-ribosyltransferase UP12_01400 573c904726abca477d3ac41c9f73ef3d 138 Gene3D G3DSA:3.20.170.40 1 138 2.5E-60 T 11-10-2018 IPR038611 Rifampin ADP-ribosyltransferase superfamily UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Gene3D G3DSA:1.10.8.60 358 463 1.2E-40 T 11-10-2018 UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 110 5.6E-7 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Gene3D G3DSA:3.40.50.300 5 182 3.7E-35 T 11-10-2018 UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 358 428 1.3E-8 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 SMART SM00382 51 359 2.7E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 SMART SM01086 358 452 9.6E-26 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 SUPERFAMILY SSF52540 6 464 2.89E-91 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Pfam PF07724 AAA domain (Cdc48 subfamily) 214 352 2.3E-41 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 7 466 6.4E-220 T 11-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Gene3D G3DSA:3.40.50.300 220 333 8.1E-26 T 11-10-2018 UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Gene3D G3DSA:1.10.8.10 250 270 8.1E-26 T 11-10-2018 UP12_07870 45c9060206941f6fc22315ed6209ae5d 466 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 466 44.13 T 11-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 SUPERFAMILY SSF48208 131 484 9.19E-81 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 Pfam PF03190 Protein of unknown function, DUF255 1 108 1.9E-42 T 11-10-2018 IPR004879 Domain of unknown function DUF255 UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 Gene3D G3DSA:1.50.10.10 154 279 8.5E-6 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 Gene3D G3DSA:1.50.10.10 335 519 9.1E-6 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 SUPERFAMILY SSF52833 1 94 4.64E-12 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 Gene3D G3DSA:3.40.30.10 1 114 3.4E-36 T 11-10-2018 UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 PIRSF PIRSF006402 1 627 6.7E-198 T 11-10-2018 IPR024705 Spermatogenesis-associated protein 20 UP12_01240 1bb6221085eb7305e8b18db96992a9dc 627 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 363 460 6.9E-5 T 11-10-2018 UP12_10570 1d44f7991826acec86aa3ea0fb8de14b 270 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 267 8.3E-108 T 11-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 UP12_10570 1d44f7991826acec86aa3ea0fb8de14b 270 Pfam PF01048 Phosphorylase superfamily 22 266 1.1E-59 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UP12_10570 1d44f7991826acec86aa3ea0fb8de14b 270 SUPERFAMILY SSF53167 4 269 3.4E-96 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UP12_10570 1d44f7991826acec86aa3ea0fb8de14b 270 PIRSF PIRSF000477 2 269 3.3E-115 T 11-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 UP12_10570 1d44f7991826acec86aa3ea0fb8de14b 270 Gene3D G3DSA:3.40.50.1580 1 269 2.4E-114 T 11-10-2018 UP12_10570 1d44f7991826acec86aa3ea0fb8de14b 270 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 266 4.4E-118 T 11-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 UP12_11490 4b031bfce64fb0af71a1fcd4c103aa01 695 Pfam PF07697 7TM-HD extracellular 37 253 8.9E-39 T 11-10-2018 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain UP12_11490 4b031bfce64fb0af71a1fcd4c103aa01 695 Gene3D G3DSA:1.10.3210.10 452 654 6.3E-28 T 11-10-2018 UP12_11490 4b031bfce64fb0af71a1fcd4c103aa01 695 SUPERFAMILY SSF109604 480 629 5.02E-16 T 11-10-2018 UP12_11490 4b031bfce64fb0af71a1fcd4c103aa01 695 Pfam PF01966 HD domain 484 625 2.9E-20 T 11-10-2018 IPR006674 HD domain UP12_11490 4b031bfce64fb0af71a1fcd4c103aa01 695 TIGRFAM TIGR00277 HDIG: HDIG domain 481 580 4.8E-29 T 11-10-2018 IPR006675 HDIG domain UP12_11490 4b031bfce64fb0af71a1fcd4c103aa01 695 Pfam PF07698 7TM receptor with intracellular HD hydrolase 260 459 3.1E-51 T 11-10-2018 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain UP12_11490 4b031bfce64fb0af71a1fcd4c103aa01 695 SMART SM00471 480 635 2.2E-12 T 11-10-2018 IPR003607 HD/PDEase domain UP12_19085 7ec2c68eab2f3293727d8caef2974737 321 SUPERFAMILY SSF52540 1 240 1.24E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_19085 7ec2c68eab2f3293727d8caef2974737 321 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_19085 7ec2c68eab2f3293727d8caef2974737 321 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 16 242 8.9E-100 T 11-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 UP12_19085 7ec2c68eab2f3293727d8caef2974737 321 Pfam PF00005 ABC transporter 19 164 9.4E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_19085 7ec2c68eab2f3293727d8caef2974737 321 SMART SM00382 27 222 5.4E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_19085 7ec2c68eab2f3293727d8caef2974737 321 Gene3D G3DSA:3.40.50.300 1 264 6.4E-79 T 11-10-2018 UP12_12540 8f5fd254efe22fb120b854c7529eff5e 508 Gene3D G3DSA:3.40.50.1390 17 150 2.8E-24 T 11-10-2018 UP12_12540 8f5fd254efe22fb120b854c7529eff5e 508 Pfam PF00239 Resolvase, N terminal domain 22 170 2.6E-22 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UP12_12540 8f5fd254efe22fb120b854c7529eff5e 508 Gene3D G3DSA:1.10.10.2600 159 303 7.9E-16 T 11-10-2018 IPR038109 DNA-binding recombinase domain superfamily UP12_12540 8f5fd254efe22fb120b854c7529eff5e 508 SUPERFAMILY SSF53041 22 170 1.31E-20 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 UP12_12540 8f5fd254efe22fb120b854c7529eff5e 508 Pfam PF07508 Recombinase 190 299 7.5E-20 T 11-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 UP12_12540 8f5fd254efe22fb120b854c7529eff5e 508 SMART SM00857 20 171 9.9E-28 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UP12_12540 8f5fd254efe22fb120b854c7529eff5e 508 Pfam PF13408 Recombinase zinc beta ribbon domain 314 379 2.1E-11 T 11-10-2018 IPR025827 Recombinase zinc beta ribbon domain UP12_08345 191dae8b0687658662a4763408b4ef64 144 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 4.4E-23 T 11-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA UP12_08345 191dae8b0687658662a4763408b4ef64 144 SUPERFAMILY SSF158622 4 123 1.44E-35 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily UP12_08345 191dae8b0687658662a4763408b4ef64 144 Gene3D G3DSA:1.20.1500.10 1 124 7.8E-38 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily UP12_08345 191dae8b0687658662a4763408b4ef64 144 PIRSF PIRSF021287 1 123 1.2E-51 T 11-10-2018 IPR016783 Biofilm formation YmcA UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 Gene3D G3DSA:1.25.10.10 214 375 6.4E-27 T 11-10-2018 IPR011989 Armadillo-like helical UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 84 4.7E-19 T 11-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 SUPERFAMILY SSF110836 1 85 1.06E-21 T 11-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 Gene3D G3DSA:3.30.1370.70 1 91 5.5E-28 T 11-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 SUPERFAMILY SSF48371 202 374 1.61E-31 T 11-10-2018 IPR016024 Armadillo-type fold UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 SMART SM00932 4 89 4.4E-25 T 11-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 Pfam PF13769 Virulence factor 109 188 1.4E-30 T 11-10-2018 IPR025989 Virulence factor domain UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 SMART SM00567 E-Z type HEAT repeats 280 309 0.0058 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 SMART SM00567 E-Z type HEAT repeats 249 278 1.6 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 SMART SM00567 E-Z type HEAT repeats 311 340 0.0063 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UP12_09815 c2fe0be87e1a4e8637371cda1365dcc3 378 Pfam PF13646 HEAT repeats 271 341 1.2E-10 T 11-10-2018 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Pfam PF00817 impB/mucB/samB family 10 157 5.4E-48 T 11-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Gene3D G3DSA:2.30.40.20 24 77 1.7E-54 T 11-10-2018 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Pfam PF11799 impB/mucB/samB family C-terminal domain 246 349 9.0E-19 T 11-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 SUPERFAMILY SSF56672 3 235 1.42E-78 T 11-10-2018 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 SUPERFAMILY SSF100879 245 342 2.35E-24 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Gene3D G3DSA:1.10.150.20 171 238 6.3E-15 T 11-10-2018 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Gene3D G3DSA:3.30.70.270 7 167 1.7E-54 T 11-10-2018 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Hamap MF_01113 DNA polymerase IV [dinB]. 4 356 36.888 T 11-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Pfam PF11798 IMS family HHH motif 171 200 6.3E-8 T 11-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UP12_10800 9e5e23ed9bb082b1debe6843962da706 414 Gene3D G3DSA:3.30.1490.100 246 353 1.3E-24 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_12140 d3bd6e7adb2208064da43f2b4528440a 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.269 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 UP12_12140 d3bd6e7adb2208064da43f2b4528440a 342 SUPERFAMILY SSF111337 1 341 7.19E-139 T 11-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 UP12_12140 d3bd6e7adb2208064da43f2b4528440a 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 1.9E-142 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 UP12_12140 d3bd6e7adb2208064da43f2b4528440a 342 Gene3D G3DSA:3.40.1780.10 14 341 1.9E-140 T 11-10-2018 UP12_12140 d3bd6e7adb2208064da43f2b4528440a 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 7.2E-155 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 UP12_12140 d3bd6e7adb2208064da43f2b4528440a 342 Gene3D G3DSA:2.40.10.240 64 162 1.9E-140 T 11-10-2018 UP12_02725 cd682a2b5244698c2dea1ef784f0f9f1 842 ProDom PD322775 PLASMID PXO2-28/BXB0027/GBAA_PXO2_0027 PXO2-28 484 839 2.0E-83 T 11-10-2018 UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.639 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 SUPERFAMILY SSF56420 2 176 1.7E-60 T 11-10-2018 IPR036821 Peptide deformylase superfamily UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 Pfam PF01327 Polypeptide deformylase 4 171 3.7E-48 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 PRINTS PR01576 Peptide deformylase signature 47 76 6.9E-32 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 PRINTS PR01576 Peptide deformylase signature 108 119 6.9E-32 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 PRINTS PR01576 Peptide deformylase signature 121 139 6.9E-32 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 PRINTS PR01576 Peptide deformylase signature 140 169 6.9E-32 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 177 2.5E-52 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 PIRSF PIRSF004749 2 185 5.1E-49 T 11-10-2018 IPR023635 Peptide deformylase UP12_07045 a25f0617443f709f28ea859fe3dfeba0 185 Gene3D G3DSA:3.90.45.10 1 184 3.4E-68 T 11-10-2018 IPR036821 Peptide deformylase superfamily UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 SUPERFAMILY SSF50341 8 153 1.57E-32 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 Pfam PF01584 CheW-like domain 19 152 1.3E-33 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 SUPERFAMILY SSF52172 173 298 9.82E-25 T 11-10-2018 IPR011006 CheY-like superfamily UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 SMART SM00448 175 297 4.3E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 Gene3D G3DSA:3.40.50.2300 161 301 6.8E-25 T 11-10-2018 UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 PIRSF PIRSF002867 2 302 4.7E-96 T 11-10-2018 IPR024181 Chemotaxis response regulator CheV UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 Gene3D G3DSA:2.30.30.40 20 143 4.4E-35 T 11-10-2018 UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 SMART SM00260 14 149 3.3E-36 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 Pfam PF00072 Response regulator receiver domain 178 297 3.7E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_06775 18e974578cf1ae818d7eb48fa61aece9 302 Gene3D G3DSA:2.40.50.180 35 149 4.4E-35 T 11-10-2018 UP12_09140 31425d5cb1c66acdf6339f4f3bb2cccd 71 Pfam PF00364 Biotin-requiring enzyme 8 69 1.2E-18 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_09140 31425d5cb1c66acdf6339f4f3bb2cccd 71 SUPERFAMILY SSF51230 3 69 6.02E-20 T 11-10-2018 IPR011053 Single hybrid motif UP12_09140 31425d5cb1c66acdf6339f4f3bb2cccd 71 Gene3D G3DSA:2.40.50.100 3 71 2.9E-25 T 11-10-2018 UP12_00235 c9564ea98b17c77ec232954c25c3a0cf 247 SUPERFAMILY SSF53335 15 199 2.81E-32 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_00235 c9564ea98b17c77ec232954c25c3a0cf 247 Pfam PF05175 Methyltransferase small domain 34 173 2.5E-11 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 UP12_00235 c9564ea98b17c77ec232954c25c3a0cf 247 Gene3D G3DSA:3.40.50.150 8 247 7.6E-74 T 11-10-2018 UP12_04220 35d3288ad3c57f943aee4fcc657153e5 188 Gene3D G3DSA:1.10.1740.10 7 89 8.3E-24 T 11-10-2018 UP12_04220 35d3288ad3c57f943aee4fcc657153e5 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 179 5.8E-36 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_04220 35d3288ad3c57f943aee4fcc657153e5 188 SUPERFAMILY SSF88946 6 107 1.49E-24 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_04220 35d3288ad3c57f943aee4fcc657153e5 188 SUPERFAMILY SSF88659 112 179 9.91E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_04220 35d3288ad3c57f943aee4fcc657153e5 188 Pfam PF04542 Sigma-70 region 2 25 93 3.9E-20 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_04220 35d3288ad3c57f943aee4fcc657153e5 188 Pfam PF08281 Sigma-70, region 4 123 175 2.0E-12 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_04220 35d3288ad3c57f943aee4fcc657153e5 188 Gene3D G3DSA:1.10.10.10 90 180 1.0E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09925 d7545611a7f934484ff20f28fe863245 501 PIRSF PIRSF006615 3 501 8.7E-199 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 Gene3D G3DSA:1.10.1370.30 1 500 5.3E-216 T 11-10-2018 UP12_09925 d7545611a7f934484ff20f28fe863245 501 SUPERFAMILY SSF55486 8 495 1.59E-117 T 11-10-2018 UP12_09925 d7545611a7f934484ff20f28fe863245 501 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 1 495 6.2E-253 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 148 168 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 333 352 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 265 284 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 447 465 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 292 308 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 245 264 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 228 244 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 402 423 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_09925 d7545611a7f934484ff20f28fe863245 501 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 379 396 8.5E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 UP12_15990 fc3a49f2609b22e7de06e64fe45f722a 314 TIGRFAM TIGR02789 nickel_nikB: nickel ABC transporter, permease subunit NikB 1 313 6.4E-143 T 11-10-2018 IPR014156 Nickel ABC transporter, permease subunit NikB GO:0015099|GO:0035444 UP12_15990 fc3a49f2609b22e7de06e64fe45f722a 314 Gene3D G3DSA:1.10.3720.10 83 310 5.3E-24 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15990 fc3a49f2609b22e7de06e64fe45f722a 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 307 1.4E-43 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_15990 fc3a49f2609b22e7de06e64fe45f722a 314 SUPERFAMILY SSF161098 94 290 3.01E-20 T 11-10-2018 IPR035906 MetI-like superfamily UP12_00425 e81e8213c6f87be62b5e0e94ccb619e8 258 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 37.021 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UP12_00425 e81e8213c6f87be62b5e0e94ccb619e8 258 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 249 2.0E-89 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UP12_00425 e81e8213c6f87be62b5e0e94ccb619e8 258 Gene3D G3DSA:3.30.420.40 89 256 5.3E-62 T 11-10-2018 UP12_00425 e81e8213c6f87be62b5e0e94ccb619e8 258 Gene3D G3DSA:3.30.420.40 1 88 8.1E-33 T 11-10-2018 UP12_00425 e81e8213c6f87be62b5e0e94ccb619e8 258 SUPERFAMILY SSF53067 124 253 9.5E-40 T 11-10-2018 UP12_00425 e81e8213c6f87be62b5e0e94ccb619e8 258 SUPERFAMILY SSF53067 2 122 3.49E-39 T 11-10-2018 UP12_00425 e81e8213c6f87be62b5e0e94ccb619e8 258 Pfam PF03309 Type III pantothenate kinase 2 206 2.6E-73 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UP12_11140 63c96601f3a4e6bdc650ea971eec7156 190 SUPERFAMILY SSF51306 39 129 7.85E-11 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily UP12_11140 63c96601f3a4e6bdc650ea971eec7156 190 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 9 166 1.5E-46 T 11-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 UP12_11140 63c96601f3a4e6bdc650ea971eec7156 190 Pfam PF00717 Peptidase S24-like 46 105 1.1E-10 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C UP12_11140 63c96601f3a4e6bdc650ea971eec7156 190 Gene3D G3DSA:2.10.109.10 42 100 2.1E-7 T 11-10-2018 UP12_11140 63c96601f3a4e6bdc650ea971eec7156 190 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 47 62 7.3E-7 T 11-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 UP12_11140 63c96601f3a4e6bdc650ea971eec7156 190 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 106 117 7.3E-7 T 11-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 UP12_15390 a8e41bbec84992f8530b18a6d8cba9de 437 SUPERFAMILY SSF101960 12 436 2.48E-119 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily UP12_15390 a8e41bbec84992f8530b18a6d8cba9de 437 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 152 428 6.3E-74 T 11-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 UP12_15390 a8e41bbec84992f8530b18a6d8cba9de 437 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 411 6.6E-63 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 UP12_01425 916104c5ef2b33e7d9fbd3fb61624dc9 109 SUPERFAMILY SSF52794 2 98 1.55E-30 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_01425 916104c5ef2b33e7d9fbd3fb61624dc9 109 Gene3D G3DSA:3.40.50.2300 1 104 9.0E-34 T 11-10-2018 UP12_01425 916104c5ef2b33e7d9fbd3fb61624dc9 109 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 88 3.7E-25 T 11-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 UP12_01425 916104c5ef2b33e7d9fbd3fb61624dc9 109 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 3.0E-16 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_17385 3496baf65f18661211af2a83594c0822 370 Gene3D G3DSA:2.40.110.10 120 232 3.8E-45 T 11-10-2018 UP12_17385 3496baf65f18661211af2a83594c0822 370 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_17385 3496baf65f18661211af2a83594c0822 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 369 2.3E-38 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UP12_17385 3496baf65f18661211af2a83594c0822 370 SUPERFAMILY SSF56645 2 240 5.5E-77 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UP12_17385 3496baf65f18661211af2a83594c0822 370 PIRSF PIRSF016578 4 354 2.7E-16 T 11-10-2018 UP12_17385 3496baf65f18661211af2a83594c0822 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 2.6E-30 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UP12_17385 3496baf65f18661211af2a83594c0822 370 SUPERFAMILY SSF47203 227 369 1.56E-41 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UP12_17385 3496baf65f18661211af2a83594c0822 370 Gene3D G3DSA:1.10.540.10 1 119 2.3E-35 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UP12_17385 3496baf65f18661211af2a83594c0822 370 Gene3D G3DSA:1.20.140.10 233 369 2.4E-40 T 11-10-2018 UP12_17385 3496baf65f18661211af2a83594c0822 370 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 5.7E-27 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UP12_13240 7a447359865e6c33c2670c48f8247e79 351 Pfam PF00487 Fatty acid desaturase 56 296 7.0E-34 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 UP12_12410 f6641bbf62be5b130eeefbfd2400ac81 365 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UP12_12410 f6641bbf62be5b130eeefbfd2400ac81 365 SMART SM01329 4 353 1.6E-196 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UP12_12410 f6641bbf62be5b130eeefbfd2400ac81 365 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 5.4E-141 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UP12_12410 f6641bbf62be5b130eeefbfd2400ac81 365 SUPERFAMILY SSF53659 1 359 9.12E-123 T 11-10-2018 UP12_12410 f6641bbf62be5b130eeefbfd2400ac81 365 Gene3D G3DSA:3.40.718.10 1 365 1.9E-153 T 11-10-2018 UP12_12410 f6641bbf62be5b130eeefbfd2400ac81 365 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 351 6.3E-165 T 11-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 UP12_12410 f6641bbf62be5b130eeefbfd2400ac81 365 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 49.693 T 11-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 UP12_13015 d5716865f102a209eb8f5040af85e4e8 309 Pfam PF07319 Primosomal protein DnaI N-terminus 1 98 3.1E-29 T 11-10-2018 IPR009928 Primosomal DnaI, N-terminal UP12_13015 d5716865f102a209eb8f5040af85e4e8 309 Gene3D G3DSA:3.40.50.300 108 299 5.1E-51 T 11-10-2018 UP12_13015 d5716865f102a209eb8f5040af85e4e8 309 SMART SM00382 158 282 8.4E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_13015 d5716865f102a209eb8f5040af85e4e8 309 SUPERFAMILY SSF52540 130 272 9.71E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13015 d5716865f102a209eb8f5040af85e4e8 309 Pfam PF01695 IstB-like ATP binding protein 127 273 1.7E-13 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 SUPERFAMILY SSF50621 245 385 1.08E-46 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 Hamap MF_01201 Alanine racemase. 5 378 33.612 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 11-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 SMART SM01005 250 378 2.8E-59 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 Gene3D G3DSA:3.20.20.10 14 230 1.3E-69 T 11-10-2018 IPR029066 PLP-binding barrel UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 Pfam PF00842 Alanine racemase, C-terminal domain 250 377 8.3E-41 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 SUPERFAMILY SSF51419 12 251 2.06E-62 T 11-10-2018 IPR029066 PLP-binding barrel UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 Gene3D G3DSA:2.40.37.10 240 393 7.8E-56 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 Pfam PF01168 Alanine racemase, N-terminal domain 12 235 5.0E-63 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 67 85 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 208 235 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 267 282 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 360 373 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 284 299 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 31 47 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 130 142 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 165 176 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 PRINTS PR00992 Alanine racemase signature 305 322 9.0E-65 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_06090 285e460a3546cb02abae68cec8c5e99b 393 TIGRFAM TIGR00492 alr: alanine racemase 6 377 1.1E-134 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 Gene3D G3DSA:3.40.50.1000 6 281 5.6E-102 T 11-10-2018 IPR023214 HAD superfamily UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 Gene3D G3DSA:3.30.1240.10 84 213 5.6E-102 T 11-10-2018 UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 284 8.2E-66 T 11-10-2018 UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 11-10-2018 UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 257 6.2E-32 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 SUPERFAMILY SSF56784 1 288 2.13E-69 T 11-10-2018 IPR036412 HAD-like superfamily UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 ProSitePatterns PS01229 Hypothetical cof family signature 2. 238 260 - T 11-10-2018 UP12_16970 2bcd17b19b642b7bb8eb77f4179b9981 289 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 284 2.3E-63 T 11-10-2018 IPR000150 Cof family GO:0016787 UP12_03875 d1d7f3681f239a4533fc0dfa77a3e215 432 Pfam PF03600 Citrate transporter 13 377 9.0E-41 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 UP12_03875 d1d7f3681f239a4533fc0dfa77a3e215 432 TIGRFAM TIGR00784 citMHS: citrate transporter 2 431 3.3E-219 T 11-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 UP12_04315 f4e92d5de2d2d8510cfc8421aa803c88 327 Pfam PF00535 Glycosyl transferase family 2 7 168 6.1E-33 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_04315 f4e92d5de2d2d8510cfc8421aa803c88 327 SUPERFAMILY SSF53448 4 253 2.44E-36 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_04315 f4e92d5de2d2d8510cfc8421aa803c88 327 Gene3D G3DSA:3.90.550.10 2 208 4.8E-34 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_04055 effe8a585e02fc298dd31193dc26dcc7 263 Pfam PF01522 Polysaccharide deacetylase 61 184 1.1E-36 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_04055 effe8a585e02fc298dd31193dc26dcc7 263 SUPERFAMILY SSF88713 51 253 1.53E-67 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_04055 effe8a585e02fc298dd31193dc26dcc7 263 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 30 253 4.1E-111 T 11-10-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA UP12_04055 effe8a585e02fc298dd31193dc26dcc7 263 Gene3D G3DSA:3.20.20.370 24 261 5.4E-93 T 11-10-2018 UP12_05325 d677073621a2a1b304ee854fdbf27f2d 391 Pfam PF00149 Calcineurin-like phosphoesterase 1 222 2.2E-13 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_05325 d677073621a2a1b304ee854fdbf27f2d 391 Gene3D G3DSA:3.60.21.10 1 272 1.1E-79 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_05325 d677073621a2a1b304ee854fdbf27f2d 391 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 276 365 8.1E-6 T 11-10-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain UP12_05325 d677073621a2a1b304ee854fdbf27f2d 391 SUPERFAMILY SSF56300 1 325 4.75E-55 T 11-10-2018 UP12_05325 d677073621a2a1b304ee854fdbf27f2d 391 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 9.1E-83 T 11-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 Gene3D G3DSA:3.40.50.720 3 247 7.8E-93 T 11-10-2018 UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 2.1E-5 T 11-10-2018 UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 244 9.9E-73 T 11-10-2018 UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.4E-49 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 7 245 6.4E-110 T 11-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.2E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.2E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.2E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 SUPERFAMILY SSF51735 4 246 2.21E-93 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_07750 8904d9ddff31535b816084c1e7cd6753 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_16120 469976359c14c96c54d8b4d1e1c08eef 543 TIGRFAM TIGR02294 nickel_nikA: nickel ABC transporter, nickel/metallophore periplasmic binding protein 45 539 6.5E-182 T 11-10-2018 IPR011980 Nickel ABC transporter, substrate-binding protein NikA GO:0015675|GO:0016151|GO:0020037 UP12_16120 469976359c14c96c54d8b4d1e1c08eef 543 Gene3D G3DSA:3.40.190.10 71 286 9.2E-144 T 11-10-2018 UP12_16120 469976359c14c96c54d8b4d1e1c08eef 543 Gene3D G3DSA:3.10.105.10 287 509 9.2E-144 T 11-10-2018 UP12_16120 469976359c14c96c54d8b4d1e1c08eef 543 SUPERFAMILY SSF53850 46 541 1.18E-120 T 11-10-2018 UP12_16120 469976359c14c96c54d8b4d1e1c08eef 543 PIRSF PIRSF002741 8 543 1.5E-102 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UP12_16120 469976359c14c96c54d8b4d1e1c08eef 543 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 454 4.9E-88 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain UP12_08465 a6f27930f9db13eda85ac4922e5a0088 326 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 5 322 1.0E-144 T 11-10-2018 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_08465 a6f27930f9db13eda85ac4922e5a0088 326 Gene3D G3DSA:1.10.620.20 3 293 2.0E-112 T 11-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 UP12_08465 a6f27930f9db13eda85ac4922e5a0088 326 PIRSF PIRSF000355 1 319 3.3E-91 T 11-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08465 a6f27930f9db13eda85ac4922e5a0088 326 SUPERFAMILY SSF47240 4 320 4.46E-91 T 11-10-2018 IPR009078 Ferritin-like superfamily UP12_08465 a6f27930f9db13eda85ac4922e5a0088 326 Pfam PF00268 Ribonucleotide reductase, small chain 8 284 2.5E-80 T 11-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08465 a6f27930f9db13eda85ac4922e5a0088 326 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 96 113 - T 11-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_09970 56573bc92bc0e474f8a3459dd4b780ad 168 SUPERFAMILY SSF51261 12 162 2.96E-55 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_09970 56573bc92bc0e474f8a3459dd4b780ad 168 Gene3D G3DSA:2.70.70.10 9 167 1.8E-59 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_09970 56573bc92bc0e474f8a3459dd4b780ad 168 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 19 142 1.2E-51 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_09970 56573bc92bc0e474f8a3459dd4b780ad 168 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 82 94 - T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_09970 56573bc92bc0e474f8a3459dd4b780ad 168 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 20 140 8.6E-45 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_07110 a938734b183433f366be44e8bcc74f41 268 Pfam PF00459 Inositol monophosphatase family 7 257 1.9E-60 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 SUPERFAMILY SSF56655 4 258 2.36E-71 T 11-10-2018 UP12_07110 a938734b183433f366be44e8bcc74f41 268 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 11-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 1.5E-35 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 1.5E-35 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.5E-35 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.5E-35 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 1.5E-35 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 1.5E-35 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 UP12_07110 a938734b183433f366be44e8bcc74f41 268 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 11-10-2018 IPR020583 Inositol monophosphatase, metal-binding site UP12_07110 a938734b183433f366be44e8bcc74f41 268 Gene3D G3DSA:3.30.540.10 2 143 4.6E-43 T 11-10-2018 UP12_07110 a938734b183433f366be44e8bcc74f41 268 Gene3D G3DSA:3.40.190.80 144 267 1.8E-31 T 11-10-2018 UP12_18980 18570def44b93a37324a18dd36a4ad10 393 Pfam PF00425 chorismate binding enzyme 121 380 2.1E-77 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal UP12_18980 18570def44b93a37324a18dd36a4ad10 393 Gene3D G3DSA:3.60.120.10 7 393 6.9E-134 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_18980 18570def44b93a37324a18dd36a4ad10 393 SUPERFAMILY SSF56322 48 389 4.84E-89 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_18980 18570def44b93a37324a18dd36a4ad10 393 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 116 387 1.5E-85 T 11-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 UP12_02765 cdad41a835b251eccd9de699ad80708a 119 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 7 119 2.0E-19 T 11-10-2018 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 241 281 320.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 443 482 3.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 157 196 210.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 32 72 1.3E-4 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 117 154 0.62 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 2 31 75.0 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 361 400 2.6 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 485 523 1.8 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 75 114 9.0E-7 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 403 440 7.4 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SMART SM00320 199 238 8.7E-8 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SUPERFAMILY SSF50978 2 316 6.1E-59 T 11-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 Pfam PF00400 WD domain, G-beta repeat 42 72 0.0046 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 Pfam PF00400 WD domain, G-beta repeat 79 114 0.0013 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 Pfam PF00400 WD domain, G-beta repeat 203 238 4.2E-6 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 Pfam PF00400 WD domain, G-beta repeat 120 153 0.0091 T 11-10-2018 IPR001680 WD40 repeat GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 Gene3D G3DSA:2.130.10.10 1 172 9.8E-38 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 SUPERFAMILY SSF50978 336 563 1.92E-30 T 11-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 Gene3D G3DSA:2.130.10.10 173 322 1.2E-22 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_03845 3029336133223c7905af9f545f32547e 585 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 101 115 - T 11-10-2018 IPR019775 WD40 repeat, conserved site UP12_03845 3029336133223c7905af9f545f32547e 585 Gene3D G3DSA:2.130.10.10 328 573 1.8E-26 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1319 1468 8.4E-35 T 11-10-2018 IPR010060 Non-ribosomal peptide synthase UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 460 855 1.9E-129 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Gene3D G3DSA:3.30.559.30 1186 1449 1.2E-52 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 SUPERFAMILY SSF52777 1030 1195 6.89E-25 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Gene3D G3DSA:3.30.559.10 1 183 6.1E-32 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 SUPERFAMILY SSF52777 3 160 3.78E-23 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Pfam PF00668 Condensation domain 16 415 1.4E-64 T 11-10-2018 IPR001242 Condensation domain UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Pfam PF00668 Condensation domain 1030 1459 7.3E-61 T 11-10-2018 IPR001242 Condensation domain UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Gene3D G3DSA:3.30.559.30 188 411 4.0E-28 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 SUPERFAMILY SSF52777 166 402 2.11E-33 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 SUPERFAMILY SSF47336 938 1005 4.58E-12 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 SUPERFAMILY SSF56801 397 947 5.76E-145 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Gene3D G3DSA:3.40.50.12780 425 824 5.0E-123 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Pfam PF13193 AMP-binding enzyme C-terminal domain 839 913 9.7E-11 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Gene3D G3DSA:1.10.1200.10 930 1009 2.8E-14 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 SUPERFAMILY SSF52777 1203 1444 1.07E-30 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Gene3D G3DSA:3.30.300.30 825 929 7.4E-32 T 11-10-2018 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Gene3D G3DSA:3.30.559.10 1010 1185 5.2E-34 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Pfam PF00550 Phosphopantetheine attachment site 944 1004 8.4E-8 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 Pfam PF00501 AMP-binding enzyme 445 831 5.2E-98 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 ProSitePatterns PS00455 Putative AMP-binding domain signature. 577 588 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 PRINTS PR00154 AMP-binding signature 584 592 8.1E-5 T 11-10-2018 IPR020459 AMP-binding UP12_03490 6018f9627b4afc40d8e495a2b23c69aa 1470 PRINTS PR00154 AMP-binding signature 572 583 8.1E-5 T 11-10-2018 IPR020459 AMP-binding UP12_06925 73836a33fe5ed41aac269b788bd27874 174 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 8 133 9.3E-24 T 11-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 UP12_06925 73836a33fe5ed41aac269b788bd27874 174 SUPERFAMILY SSF52540 8 115 1.17E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06925 73836a33fe5ed41aac269b788bd27874 174 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 8 134 1.4E-24 T 11-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 UP12_06925 73836a33fe5ed41aac269b788bd27874 174 Gene3D G3DSA:3.40.50.300 6 171 3.9E-41 T 11-10-2018 UP12_01745 6e139ad27b1d9dea924a8310795594f2 395 Gene3D G3DSA:1.20.1250.20 200 379 8.9E-21 T 11-10-2018 UP12_01745 6e139ad27b1d9dea924a8310795594f2 395 SUPERFAMILY SSF103473 3 381 1.1E-38 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01745 6e139ad27b1d9dea924a8310795594f2 395 Gene3D G3DSA:1.20.1250.20 4 185 1.3E-16 T 11-10-2018 UP12_01745 6e139ad27b1d9dea924a8310795594f2 395 Pfam PF07690 Major Facilitator Superfamily 11 318 7.9E-21 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_19100 8dc000e86d553a71f273898c610e7f17 95 Pfam PF01250 Ribosomal protein S6 3 92 2.4E-29 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19100 8dc000e86d553a71f273898c610e7f17 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.9E-35 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19100 8dc000e86d553a71f273898c610e7f17 95 SUPERFAMILY SSF54995 1 93 6.67E-34 T 11-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19100 8dc000e86d553a71f273898c610e7f17 95 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 11-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 UP12_19100 8dc000e86d553a71f273898c610e7f17 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 23.073 T 11-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 UP12_19100 8dc000e86d553a71f273898c610e7f17 95 Gene3D G3DSA:3.30.70.60 1 95 5.5E-36 T 11-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 UP12_15945 7822b7bdedc881e85620bee581c76314 397 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 5 392 1.0E-162 T 11-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_15945 7822b7bdedc881e85620bee581c76314 397 Pfam PF00202 Aminotransferase class-III 15 393 9.6E-134 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_15945 7822b7bdedc881e85620bee581c76314 397 SUPERFAMILY SSF53383 2 395 7.89E-123 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_15945 7822b7bdedc881e85620bee581c76314 397 Gene3D G3DSA:3.90.1150.10 23 385 7.5E-152 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_15945 7822b7bdedc881e85620bee581c76314 397 Hamap MF_01689 Ornithine aminotransferase [rocD]. 4 396 65.712 T 11-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 UP12_15945 7822b7bdedc881e85620bee581c76314 397 Gene3D G3DSA:3.40.640.10 58 306 7.5E-152 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_15945 7822b7bdedc881e85620bee581c76314 397 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_15945 7822b7bdedc881e85620bee581c76314 397 PIRSF PIRSF000521 174 397 1.1E-29 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_15945 7822b7bdedc881e85620bee581c76314 397 PIRSF PIRSF000521 1 159 2.2E-8 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_17990 16e5af853eb62675432f74b525a6ef33 108 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 5 98 1.9E-38 T 11-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 UP12_17990 16e5af853eb62675432f74b525a6ef33 108 Gene3D G3DSA:1.20.58.280 1 104 6.1E-42 T 11-10-2018 UP12_17990 16e5af853eb62675432f74b525a6ef33 108 PIRSF PIRSF000699 1 104 1.4E-41 T 11-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 UP12_17990 16e5af853eb62675432f74b525a6ef33 108 SUPERFAMILY SSF46973 1 99 1.57E-38 T 11-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 UP12_05160 93881c7e79590dceb9ebdb0411262a23 470 Pfam PF01593 Flavin containing amine oxidoreductase 15 460 2.0E-65 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UP12_05160 93881c7e79590dceb9ebdb0411262a23 470 Gene3D G3DSA:1.10.3110.10 110 203 2.3E-152 T 11-10-2018 UP12_05160 93881c7e79590dceb9ebdb0411262a23 470 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 5 470 4.6E-157 T 11-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 UP12_05160 93881c7e79590dceb9ebdb0411262a23 470 SUPERFAMILY SSF51905 6 460 9.81E-49 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05160 93881c7e79590dceb9ebdb0411262a23 470 Gene3D G3DSA:3.90.660.20 44 414 2.3E-152 T 11-10-2018 UP12_05160 93881c7e79590dceb9ebdb0411262a23 470 Gene3D G3DSA:3.50.50.60 9 456 2.3E-152 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05160 93881c7e79590dceb9ebdb0411262a23 470 SUPERFAMILY SSF54373 308 415 3.53E-33 T 11-10-2018 UP12_17650 a00a0b855d5932b0b5c0fe9c0277c75b 246 Pfam PF00483 Nucleotidyl transferase 2 235 8.6E-50 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UP12_17650 a00a0b855d5932b0b5c0fe9c0277c75b 246 Gene3D G3DSA:3.90.550.10 1 246 1.6E-64 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_17650 a00a0b855d5932b0b5c0fe9c0277c75b 246 SUPERFAMILY SSF53448 2 235 2.25E-64 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_09965 cec9356d01244fa83776abf1e4b76267 374 Gene3D G3DSA:3.20.20.70 5 371 9.4E-103 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_09965 cec9356d01244fa83776abf1e4b76267 374 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 10 339 2.4E-96 T 11-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 UP12_09965 cec9356d01244fa83776abf1e4b76267 374 SUPERFAMILY SSF51395 7 342 9.02E-92 T 11-10-2018 UP12_02560 78e330878f62a409281f5cc0a0e042f8 133 Gene3D G3DSA:3.30.565.10 7 130 5.3E-16 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02560 78e330878f62a409281f5cc0a0e042f8 133 SUPERFAMILY SSF55874 21 127 1.9E-13 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02560 78e330878f62a409281f5cc0a0e042f8 133 Pfam PF13581 Histidine kinase-like ATPase domain 15 129 1.9E-7 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06640 7b495373072fb1abccf7f43fa9021ec7 165 SUPERFAMILY SSF55620 28 136 7.41E-29 T 11-10-2018 UP12_06640 7b495373072fb1abccf7f43fa9021ec7 165 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 28 139 3.5E-54 T 11-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 UP12_06640 7b495373072fb1abccf7f43fa9021ec7 165 Pfam PF14489 QueF-like protein 62 140 6.3E-35 T 11-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 UP12_06640 7b495373072fb1abccf7f43fa9021ec7 165 Gene3D G3DSA:3.30.1130.10 21 165 7.7E-68 T 11-10-2018 UP12_06640 7b495373072fb1abccf7f43fa9021ec7 165 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 165 71.417 T 11-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 UP12_06640 7b495373072fb1abccf7f43fa9021ec7 165 PIRSF PIRSF027377 9 147 1.1E-60 T 11-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 SMART SM00228 329 419 1.8E-13 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 Gene3D G3DSA:2.40.10.10 212 328 1.4E-40 T 11-10-2018 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 Pfam PF13365 Trypsin-like peptidase domain 147 291 4.9E-32 T 11-10-2018 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 PRINTS PR00834 HtrA/DegQ protease family signature 180 200 1.4E-38 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 PRINTS PR00834 HtrA/DegQ protease family signature 221 245 1.4E-38 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 PRINTS PR00834 HtrA/DegQ protease family signature 376 388 1.4E-38 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 PRINTS PR00834 HtrA/DegQ protease family signature 159 171 1.4E-38 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 PRINTS PR00834 HtrA/DegQ protease family signature 262 279 1.4E-38 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 PRINTS PR00834 HtrA/DegQ protease family signature 284 301 1.4E-38 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 SUPERFAMILY SSF50494 94 325 7.98E-59 T 11-10-2018 IPR009003 Peptidase S1, PA clan UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 Gene3D G3DSA:2.30.42.10 329 437 1.8E-26 T 11-10-2018 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 Pfam PF13180 PDZ domain 329 428 1.8E-22 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 SUPERFAMILY SSF50156 310 428 7.49E-22 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_06265 f3ff2a0d5ad1960bbccdadb7e364a136 438 Gene3D G3DSA:2.40.10.10 82 202 1.4E-28 T 11-10-2018 UP12_18850 9f80b3930d25693b1364677e3403fe8d 286 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 6 271 1.6E-73 T 11-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase UP12_18850 9f80b3930d25693b1364677e3403fe8d 286 Gene3D G3DSA:3.40.50.10790 1 166 2.8E-50 T 11-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal UP12_18850 9f80b3930d25693b1364677e3403fe8d 286 SUPERFAMILY SSF101852 171 276 2.09E-29 T 11-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal UP12_18850 9f80b3930d25693b1364677e3403fe8d 286 SUPERFAMILY SSF102522 5 167 3.53E-55 T 11-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal UP12_18850 9f80b3930d25693b1364677e3403fe8d 286 PIRSF PIRSF006779 1 278 4.2E-96 T 11-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase UP12_18850 9f80b3930d25693b1364677e3403fe8d 286 Gene3D G3DSA:2.40.30.90 167 283 2.4E-34 T 11-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 461 88.915 T 11-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 Gene3D G3DSA:1.10.275.10 5 137 1.3E-54 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 Pfam PF00206 Lyase 12 341 1.8E-116 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 Gene3D G3DSA:1.20.200.10 138 406 1.3E-113 T 11-10-2018 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 459 1.5E-248 T 11-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 SUPERFAMILY SSF48557 4 459 2.67E-154 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 2.1E-5 T 11-10-2018 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 2.1E-5 T 11-10-2018 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 Pfam PF10415 Fumarase C C-terminus 407 459 9.6E-26 T 11-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 3.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 3.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 3.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 3.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15515 3ea38a1e32e3b7d32ef4f475357c0bc6 464 Gene3D G3DSA:1.10.40.30 407 464 6.2E-28 T 11-10-2018 UP12_09945 fe06a8e25cea21f1b76da78689154165 101 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 97 24.007 T 11-10-2018 IPR011229 Cell cycle protein GpsB UP12_09945 fe06a8e25cea21f1b76da78689154165 101 PIRSF PIRSF029938 1 101 3.8E-40 T 11-10-2018 IPR011229 Cell cycle protein GpsB UP12_09945 fe06a8e25cea21f1b76da78689154165 101 Pfam PF05103 DivIVA protein 8 67 6.4E-15 T 11-10-2018 IPR007793 DivIVA family UP12_09945 fe06a8e25cea21f1b76da78689154165 101 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 9.0E-15 T 11-10-2018 IPR019933 DivIVA domain UP12_06590 2de0863eeadb580abaad0a198ed347a4 80 SUPERFAMILY SSF140500 6 57 5.62E-15 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 UP12_06590 2de0863eeadb580abaad0a198ed347a4 80 Pfam PF09388 Spo0E like sporulation regulatory protein 10 50 4.8E-14 T 11-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 UP12_06590 2de0863eeadb580abaad0a198ed347a4 80 Gene3D G3DSA:1.20.58.990 6 66 5.5E-10 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 UP12_05490 2329a0bae155af821b375ab7d263038a 613 Gene3D G3DSA:3.20.20.220 311 597 3.6E-50 T 11-10-2018 UP12_05490 2329a0bae155af821b375ab7d263038a 613 Gene3D G3DSA:3.20.20.330 2 293 1.7E-89 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UP12_05490 2329a0bae155af821b375ab7d263038a 613 Pfam PF02219 Methylenetetrahydrofolate reductase 313 572 4.4E-29 T 11-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 UP12_05490 2329a0bae155af821b375ab7d263038a 613 SUPERFAMILY SSF82282 2 359 7.72E-101 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UP12_05490 2329a0bae155af821b375ab7d263038a 613 SUPERFAMILY SSF51730 312 600 1.86E-68 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like UP12_05490 2329a0bae155af821b375ab7d263038a 613 Pfam PF02574 Homocysteine S-methyltransferase 12 280 1.4E-60 T 11-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UP12_11295 de177d61a823cf2d53cbe37c360cf7d3 270 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_11295 de177d61a823cf2d53cbe37c360cf7d3 270 Gene3D G3DSA:3.40.50.300 21 268 1.3E-62 T 11-10-2018 UP12_11295 de177d61a823cf2d53cbe37c360cf7d3 270 SMART SM00382 48 242 4.0E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_11295 de177d61a823cf2d53cbe37c360cf7d3 270 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 24 270 4.1E-121 T 11-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 UP12_11295 de177d61a823cf2d53cbe37c360cf7d3 270 Pfam PF00005 ABC transporter 40 194 1.7E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_11295 de177d61a823cf2d53cbe37c360cf7d3 270 SUPERFAMILY SSF52540 15 257 4.19E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13040 387b01b7e54d580c340b5847500f313f 340 SUPERFAMILY SSF55347 152 314 4.76E-72 T 11-10-2018 UP12_13040 387b01b7e54d580c340b5847500f313f 340 PIRSF PIRSF000149 1 335 1.7E-137 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 102 8.1E-37 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 Gene3D G3DSA:3.30.360.10 151 315 2.5E-151 T 11-10-2018 UP12_13040 387b01b7e54d580c340b5847500f313f 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 7.0E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 7.0E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 7.0E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 7.0E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 7.0E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 11-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 SMART SM00846 3 152 7.4E-87 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 1.0E-68 T 11-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_13040 387b01b7e54d580c340b5847500f313f 340 Gene3D G3DSA:3.40.50.720 5 328 2.5E-151 T 11-10-2018 UP12_13040 387b01b7e54d580c340b5847500f313f 340 SUPERFAMILY SSF51735 1 179 2.32E-61 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13040 387b01b7e54d580c340b5847500f313f 340 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 5 325 2.4E-134 T 11-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_05140 ee40f969327b40d2b325eff52c51f0d2 161 SUPERFAMILY SSF54909 66 155 4.54E-19 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_05140 ee40f969327b40d2b325eff52c51f0d2 161 Pfam PF03992 Antibiotic biosynthesis monooxygenase 69 135 1.8E-8 T 11-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UP12_05140 ee40f969327b40d2b325eff52c51f0d2 161 Gene3D G3DSA:3.30.70.3430 1 159 3.8E-51 T 11-10-2018 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 SUPERFAMILY SSF69065 14 175 1.22E-52 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 Gene3D G3DSA:3.30.160.20 173 240 1.2E-22 T 11-10-2018 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 SMART SM00535 33 168 4.3E-61 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 21 240 4.3E-81 T 11-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 Gene3D G3DSA:1.10.1520.10 17 165 4.3E-48 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 SMART SM00358 174 241 4.0E-21 T 11-10-2018 IPR014720 Double-stranded RNA-binding domain UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 Pfam PF14622 Ribonuclease-III-like 31 160 1.9E-36 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 Hamap MF_00104 Ribonuclease 3 [rnc]. 21 237 32.046 T 11-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 ProSitePatterns PS00517 Ribonuclease III family signature. 57 65 - T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 SUPERFAMILY SSF54768 169 243 3.77E-23 T 11-10-2018 UP12_07760 cbf0a3d0c27407c0842e5132d2aac964 247 Pfam PF00035 Double-stranded RNA binding motif 175 240 1.2E-16 T 11-10-2018 IPR014720 Double-stranded RNA-binding domain UP12_03000 262fac642af51166f619a317a0c2eda7 182 Pfam PF01872 RibD C-terminal domain 11 168 8.4E-22 T 11-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UP12_03000 262fac642af51166f619a317a0c2eda7 182 Gene3D G3DSA:3.40.430.10 5 177 2.5E-48 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_03000 262fac642af51166f619a317a0c2eda7 182 SUPERFAMILY SSF53597 7 168 1.15E-36 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 SMART SM00065 238 373 1.9E-9 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 Pfam PF13492 GAF domain 250 364 2.4E-6 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 576 1.2E-7 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 Gene3D G3DSA:3.30.565.10 433 577 4.5E-15 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 Pfam PF07694 5TMR of 5TMR-LYT 26 207 1.0E-59 T 11-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 Pfam PF06580 Histidine kinase 378 456 6.9E-23 T 11-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 SUPERFAMILY SSF55874 433 575 1.17E-13 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_12985 26f5af535ada6297ffc5b6f3b8e90fff 585 SUPERFAMILY SSF55781 243 364 1.82E-7 T 11-10-2018 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 SUPERFAMILY SSF51905 8 311 7.92E-42 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 3.8E-20 T 11-10-2018 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 3.8E-20 T 11-10-2018 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.8E-20 T 11-10-2018 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 3.8E-20 T 11-10-2018 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 4.5E-24 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 65 75 4.5E-24 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 4.5E-24 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 4.5E-24 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 4.5E-24 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 Gene3D G3DSA:3.50.50.60 8 305 9.7E-88 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 Hamap MF_01685 Ferredoxin--NADP reductase. 7 330 38.581 T 11-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 Gene3D G3DSA:3.50.50.60 128 247 9.7E-88 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_04195 5d911aeacd2a5840b84278d49d58299b 346 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 295 4.9E-32 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 290 301 1.3E-28 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 52 66 1.3E-28 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 125 139 1.3E-28 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 1.3E-28 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00102 Ornithine carbamoyltransferase signature 85 98 1.3E-28 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 Gene3D G3DSA:3.40.50.1370 139 306 5.8E-126 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 Gene3D G3DSA:3.40.50.1370 13 138 5.8E-126 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 12 312 81.51 T 11-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 273 1.0E-27 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 54 73 1.0E-27 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 276 299 1.0E-27 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 1.0E-27 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 13 311 7.7E-133 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 SUPERFAMILY SSF53671 10 311 2.62E-112 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 13 149 1.4E-54 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 54 61 - T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_05595 3f32cb16ee33ce3ed570d12f9d1f939d 316 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 307 4.4E-60 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 UP12_02040 ddeaeb087db06ca6cc51db98db358a21 230 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 104 229 2.7E-33 T 11-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UP12_02040 ddeaeb087db06ca6cc51db98db358a21 230 Gene3D G3DSA:3.90.470.20 107 209 2.2E-73 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_02040 ddeaeb087db06ca6cc51db98db358a21 230 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 106 208 1.5E-18 T 11-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_02040 ddeaeb087db06ca6cc51db98db358a21 230 Gene3D G3DSA:3.90.470.20 17 222 2.2E-73 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_02040 ddeaeb087db06ca6cc51db98db358a21 230 SUPERFAMILY SSF56214 7 99 1.31E-23 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_02040 ddeaeb087db06ca6cc51db98db358a21 230 SUPERFAMILY SSF56214 106 227 3.92E-31 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_15850 f7def29f7a160fc5df58d449baca5710 305 Gene3D G3DSA:3.40.190.120 139 243 1.7E-98 T 11-10-2018 UP12_15850 f7def29f7a160fc5df58d449baca5710 305 Gene3D G3DSA:3.40.190.10 38 299 1.7E-98 T 11-10-2018 UP12_15850 f7def29f7a160fc5df58d449baca5710 305 SUPERFAMILY SSF53850 35 303 3.26E-68 T 11-10-2018 UP12_15850 f7def29f7a160fc5df58d449baca5710 305 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 300 9.3E-62 T 11-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 2.1E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.1E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 2.1E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 2.1E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 SUPERFAMILY SSF46785 9 139 1.8E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 Pfam PF01047 MarR family 34 91 1.0E-17 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 Gene3D G3DSA:1.10.10.10 1 141 1.5E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09715 2978261cb11efa2de4d8e56dba8d6a1a 143 SMART SM00347 27 127 3.9E-31 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_02340 b2a4de72803cde84120d59f07feffa24 275 SUPERFAMILY SSF46689 217 263 1.34E-7 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_02340 b2a4de72803cde84120d59f07feffa24 275 Pfam PF02311 AraC-like ligand binding domain 16 125 3.4E-16 T 11-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 UP12_02340 b2a4de72803cde84120d59f07feffa24 275 SUPERFAMILY SSF51215 14 147 1.29E-20 T 11-10-2018 IPR037923 Transcription regulator HTH-like UP12_02340 b2a4de72803cde84120d59f07feffa24 275 SUPERFAMILY SSF46689 165 215 3.76E-9 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_02340 b2a4de72803cde84120d59f07feffa24 275 Gene3D G3DSA:1.10.10.60 163 214 4.5E-12 T 11-10-2018 UP12_02340 b2a4de72803cde84120d59f07feffa24 275 Pfam PF12833 Helix-turn-helix domain 190 263 4.4E-18 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_02340 b2a4de72803cde84120d59f07feffa24 275 Gene3D G3DSA:1.10.10.60 215 267 8.5E-11 T 11-10-2018 UP12_02340 b2a4de72803cde84120d59f07feffa24 275 Gene3D G3DSA:2.60.120.10 14 99 4.2E-6 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_02340 b2a4de72803cde84120d59f07feffa24 275 SMART SM00342 181 263 3.6E-24 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 SUPERFAMILY SSF110849 32 132 2.88E-29 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 Gene3D G3DSA:3.90.1530.30 51 115 1.6E-25 T 11-10-2018 UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 SUPERFAMILY SSF109709 123 228 1.28E-32 T 11-10-2018 UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 Gene3D G3DSA:1.10.10.2830 116 229 1.3E-35 T 11-10-2018 UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 36 291 1.3E-112 T 11-10-2018 IPR023705 Nucleoid occlusion protein UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 34 215 6.3E-64 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 291 38.641 T 11-10-2018 IPR023705 Nucleoid occlusion protein UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 Pfam PF02195 ParB-like nuclease domain 39 128 4.7E-28 T 11-10-2018 IPR003115 ParB/Sulfiredoxin UP12_19150 4a6f1974962720ecca9b98df1d34b2e5 291 SMART SM00470 38 129 4.8E-36 T 11-10-2018 IPR003115 ParB/Sulfiredoxin UP12_17175 dd874295077f122a5f0692d5ade52057 131 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 129 6.5E-41 T 11-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17175 dd874295077f122a5f0692d5ade52057 131 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 1.1E-29 T 11-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17175 dd874295077f122a5f0692d5ade52057 131 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 86 9.0E-32 T 11-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17175 dd874295077f122a5f0692d5ade52057 131 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 128 23.736 T 11-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17175 dd874295077f122a5f0692d5ade52057 131 SUPERFAMILY SSF46604 87 129 5.75E-6 T 11-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17175 dd874295077f122a5f0692d5ade52057 131 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 130 4.9E-16 T 11-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain UP12_17175 dd874295077f122a5f0692d5ade52057 131 SUPERFAMILY SSF51344 3 83 2.75E-24 T 11-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17175 dd874295077f122a5f0692d5ade52057 131 Gene3D G3DSA:2.60.15.10 1 88 2.1E-32 T 11-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17175 dd874295077f122a5f0692d5ade52057 131 Gene3D G3DSA:1.20.5.440 89 130 8.9E-16 T 11-10-2018 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 Gene3D G3DSA:3.40.50.720 6 178 1.1E-58 T 11-10-2018 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 SUPERFAMILY SSF51735 7 187 5.51E-62 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 193 488 7.1E-113 T 11-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 SUPERFAMILY SSF55347 185 489 4.58E-116 T 11-10-2018 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 190 3.3E-61 T 11-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 PIRSF PIRSF000110 1 491 4.8E-187 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 Gene3D G3DSA:3.30.360.10 179 490 1.7E-123 T 11-10-2018 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 9 490 88.854 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 180 186 - T 11-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 170 198 1.1E-47 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 256 1.1E-47 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 146 159 1.1E-47 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 331 357 1.1E-47 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 222 239 1.1E-47 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_10755 c8728b13eb7adc8213e2de4305e5f1b7 491 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 490 8.5E-202 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 UP12_01750 19e5bc7ee67e28f7d4cf6b9e6ffc67c4 209 Pfam PF01810 LysE type translocator 12 203 1.8E-46 T 11-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UP12_11950 25c089d3b0a274d786bf6684a650805b 360 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 17 357 33.885 T 11-10-2018 IPR003770 Endolytic murein transglycosylase UP12_11950 25c089d3b0a274d786bf6684a650805b 360 Pfam PF02618 YceG-like family 54 353 9.8E-83 T 11-10-2018 IPR003770 Endolytic murein transglycosylase UP12_11950 25c089d3b0a274d786bf6684a650805b 360 Gene3D G3DSA:1.10.8.1150 48 122 1.7E-24 T 11-10-2018 UP12_11950 25c089d3b0a274d786bf6684a650805b 360 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 15 357 2.7E-120 T 11-10-2018 IPR003770 Endolytic murein transglycosylase UP12_11950 25c089d3b0a274d786bf6684a650805b 360 Gene3D G3DSA:3.30.160.60 327 359 1.9E-5 T 11-10-2018 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 SMART SM00490 244 325 9.4E-28 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Pfam PF09382 RQC domain 402 511 2.7E-31 T 11-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Pfam PF16124 RecQ zinc-binding 339 399 2.8E-14 T 11-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 SMART SM00487 14 212 3.3E-30 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 SMART SM00341 514 592 3.3E-19 T 11-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 457 3.1E-138 T 11-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 SMART SM00956 406 509 1.9E-39 T 11-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 SUPERFAMILY SSF52540 59 347 2.6E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Gene3D G3DSA:1.10.10.10 335 511 1.8E-44 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Gene3D G3DSA:3.40.50.300 203 334 8.6E-40 T 11-10-2018 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Pfam PF00271 Helicase conserved C-terminal domain 226 324 4.0E-17 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Gene3D G3DSA:1.10.150.80 512 592 1.9E-25 T 11-10-2018 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Pfam PF00570 HRDC domain 518 584 9.2E-25 T 11-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 SUPERFAMILY SSF47819 515 591 2.16E-26 T 11-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 7 585 2.6E-230 T 11-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Gene3D G3DSA:3.40.50.300 1 202 6.0E-76 T 11-10-2018 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 Pfam PF00270 DEAD/DEAH box helicase 21 183 2.1E-20 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_09480 38e85aaf343fcedbdbbce59b9f2376a0 593 SUPERFAMILY SSF46785 397 539 9.11E-34 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03605 7f24635fbeea93526e7a332715d2427a 302 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 128 1.3E-37 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UP12_03605 7f24635fbeea93526e7a332715d2427a 302 SUPERFAMILY SSF111331 1 295 6.1E-86 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UP12_03605 7f24635fbeea93526e7a332715d2427a 302 Gene3D G3DSA:2.60.200.40 126 279 3.3E-91 T 11-10-2018 UP12_03605 7f24635fbeea93526e7a332715d2427a 302 Gene3D G3DSA:3.40.50.10330 6 125 3.3E-91 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UP12_03605 7f24635fbeea93526e7a332715d2427a 302 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 295 1.6E-121 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase UP12_03605 7f24635fbeea93526e7a332715d2427a 302 SMART SM00046 3 131 3.2E-6 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 330 33.805 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 SUPERFAMILY SSF55781 71 340 2.16E-71 T 11-10-2018 UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 Pfam PF01628 HrcA protein C terminal domain 104 323 5.6E-67 T 11-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 336 1.7E-115 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 Gene3D G3DSA:1.10.10.10 1 85 2.0E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 Gene3D G3DSA:3.30.390.60 128 230 2.3E-60 T 11-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 PIRSF PIRSF005485 1 341 4.9E-125 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 SUPERFAMILY SSF46785 1 84 4.21E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_11570 2e26df26d3c34cd5777ff5e4be55e265 343 Gene3D G3DSA:3.30.450.40 104 336 2.3E-60 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_09185 2c5aaf62ab8b76b16b61d1aff5e0b371 377 Gene3D G3DSA:1.10.10.2840 243 367 5.6E-19 T 11-10-2018 UP12_09185 2c5aaf62ab8b76b16b61d1aff5e0b371 377 Pfam PF13556 PucR C-terminal helix-turn-helix domain 304 361 5.6E-18 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_09185 2c5aaf62ab8b76b16b61d1aff5e0b371 377 Pfam PF05651 Putative sugar diacid recognition 2 135 1.6E-43 T 11-10-2018 IPR008599 Putative sugar diacid recognition UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 SUPERFAMILY SSF53335 4 275 6.89E-90 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 TIGRFAM TIGR00417 speE: spermidine synthase 5 270 6.4E-125 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 4 276 41.791 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 80 93 - T 11-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 Pfam PF01564 Spermine/spermidine synthase domain 59 237 8.6E-71 T 11-10-2018 UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 Pfam PF17284 Spermidine synthase tetramerisation domain 4 56 9.6E-22 T 11-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 Gene3D G3DSA:2.30.140.10 2 53 3.0E-26 T 11-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 UP12_17460 dafd43fd16b257dcfb69bad1efdd57a1 276 Gene3D G3DSA:3.40.50.150 54 275 1.0E-75 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 ProSitePatterns PS00012 Phosphopantetheine attachment site. 993 1008 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF47336 963 1035 1.96E-20 T 11-10-2018 IPR036736 ACP-like superfamily UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF56801 1481 2057 2.88E-166 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF52777 191 450 2.56E-41 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.30.559.30 208 433 3.7E-63 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.40.50.12780 451 855 6.6E-141 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.40.50.12780 1508 1929 7.2E-149 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF13193 AMP-binding enzyme C-terminal domain 1943 2018 6.1E-14 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF13193 AMP-binding enzyme C-terminal domain 869 944 8.8E-16 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF53474 2111 2375 2.11E-57 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF00550 Phosphopantetheine attachment site 2046 2107 4.4E-14 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF00550 Phosphopantetheine attachment site 972 1034 7.3E-16 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2068 2083 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.30.559.30 1231 1488 2.1E-147 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.30.300.30 1930 2034 7.3E-37 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.30.300.30 856 958 1.1E-38 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF52777 11 185 2.56E-34 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF00975 Thioesterase domain 2132 2360 1.2E-31 T 11-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1543 1959 7.0E-138 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 486 883 3.6E-137 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:1.10.1200.10 959 1040 9.1E-28 T 11-10-2018 IPR036736 ACP-like superfamily UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 ProSitePatterns PS00455 Putative AMP-binding domain signature. 608 619 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF47336 2038 2109 8.38E-19 T 11-10-2018 IPR036736 ACP-like superfamily UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1670 1681 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.30.559.10 1054 1426 2.1E-147 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.30.559.10 11 207 1.3E-54 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF52777 1055 1227 1.0E-46 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF56801 428 982 7.2E-166 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF00668 Condensation domain 8 446 8.3E-77 T 11-10-2018 IPR001242 Condensation domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF00668 Condensation domain 1051 1501 8.7E-105 T 11-10-2018 IPR001242 Condensation domain UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SUPERFAMILY SSF52777 1240 1491 7.11E-60 T 11-10-2018 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SMART SM00823 Phosphopantetheine attachment site 2044 2113 3.3E-10 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 SMART SM00823 Phosphopantetheine attachment site 969 1038 3.9E-8 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF00501 AMP-binding enzyme 465 861 5.7E-106 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Pfam PF00501 AMP-binding enzyme 1522 1935 1.4E-109 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_18995 31c83aa995a3647c19efd128ea7058df 2382 Gene3D G3DSA:3.40.50.1820 2035 2377 4.4E-112 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_16225 785e7ea6e6f79f4e215a9843cb5425d5 154 PRINTS PR00502 NUDIX hydrolase family signature 40 55 6.1E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_16225 785e7ea6e6f79f4e215a9843cb5425d5 154 PRINTS PR00502 NUDIX hydrolase family signature 26 40 6.1E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_16225 785e7ea6e6f79f4e215a9843cb5425d5 154 Pfam PF00293 NUDIX domain 3 121 8.2E-16 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UP12_16225 785e7ea6e6f79f4e215a9843cb5425d5 154 SUPERFAMILY SSF55811 4 128 9.21E-28 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UP12_16225 785e7ea6e6f79f4e215a9843cb5425d5 154 Gene3D G3DSA:3.90.79.10 1 153 1.5E-42 T 11-10-2018 UP12_15705 c080a19db338e972720aff8771a45b1b 137 Gene3D G3DSA:1.20.1550.10 1 112 1.1E-8 T 11-10-2018 IPR023380 DsbB-like superfamily UP12_15705 c080a19db338e972720aff8771a45b1b 137 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 1 137 23.801 T 11-10-2018 IPR012187 Disulphide bond formation protein BdbC UP12_15705 c080a19db338e972720aff8771a45b1b 137 Pfam PF02600 Disulfide bond formation protein DsbB 11 109 4.3E-7 T 11-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 UP12_15705 c080a19db338e972720aff8771a45b1b 137 SUPERFAMILY SSF158442 8 131 1.31E-29 T 11-10-2018 IPR023380 DsbB-like superfamily UP12_15705 c080a19db338e972720aff8771a45b1b 137 PIRSF PIRSF036659 1 137 7.5E-55 T 11-10-2018 IPR012187 Disulphide bond formation protein BdbC UP12_09850 086f9a31770f42a104e1845cb146a82a 66 SUPERFAMILY SSF50249 1 65 4.18E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_09850 086f9a31770f42a104e1845cb146a82a 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.1E-30 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_09850 086f9a31770f42a104e1845cb146a82a 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 11-10-2018 IPR019844 Cold-shock conserved site UP12_09850 086f9a31770f42a104e1845cb146a82a 66 Gene3D G3DSA:2.40.50.140 1 65 7.6E-31 T 11-10-2018 UP12_09850 086f9a31770f42a104e1845cb146a82a 66 PIRSF PIRSF002599 1 66 3.9E-24 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 UP12_09850 086f9a31770f42a104e1845cb146a82a 66 SMART SM00357 3 66 2.8E-29 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 UP12_09850 086f9a31770f42a104e1845cb146a82a 66 PRINTS PR00050 Cold shock protein signature 39 57 5.0E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_09850 086f9a31770f42a104e1845cb146a82a 66 PRINTS PR00050 Cold shock protein signature 24 33 5.0E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_09850 086f9a31770f42a104e1845cb146a82a 66 PRINTS PR00050 Cold shock protein signature 4 19 5.0E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_09260 b89b9ab5695d45b34936a1d9f807d710 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 19 422 2.6E-94 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_09260 b89b9ab5695d45b34936a1d9f807d710 455 PIRSF PIRSF006603 3 454 7.9E-127 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_09260 b89b9ab5695d45b34936a1d9f807d710 455 Pfam PF01554 MatE 19 179 1.3E-39 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_09260 b89b9ab5695d45b34936a1d9f807d710 455 Pfam PF01554 MatE 248 409 2.0E-31 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_03075 323a8ad064f3152afbaa994deac92ba6 339 Pfam PF02016 LD-carboxypeptidase 13 323 8.3E-68 T 11-10-2018 IPR003507 Peptidase family S66 UP12_03075 323a8ad064f3152afbaa994deac92ba6 339 SUPERFAMILY SSF52317 1 158 7.32E-37 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_03075 323a8ad064f3152afbaa994deac92ba6 339 Gene3D G3DSA:3.50.30.60 160 337 2.5E-35 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_03075 323a8ad064f3152afbaa994deac92ba6 339 SUPERFAMILY SSF141986 171 325 4.58E-28 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_03075 323a8ad064f3152afbaa994deac92ba6 339 Gene3D G3DSA:3.40.50.10740 2 159 2.5E-35 T 11-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal UP12_03075 323a8ad064f3152afbaa994deac92ba6 339 PIRSF PIRSF028757 1 337 3.2E-65 T 11-10-2018 IPR003507 Peptidase family S66 UP12_08690 ab58595e28c806131a1e334914511edd 215 SUPERFAMILY SSF53041 1 148 4.97E-24 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 UP12_08690 ab58595e28c806131a1e334914511edd 215 SMART SM00857 3 149 4.9E-32 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UP12_08690 ab58595e28c806131a1e334914511edd 215 Gene3D G3DSA:3.40.50.1390 1 152 1.3E-25 T 11-10-2018 UP12_08690 ab58595e28c806131a1e334914511edd 215 Pfam PF00239 Resolvase, N terminal domain 3 147 3.3E-23 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 UP12_08555 e9bcd53e6a489eba93e5cb31574b28bb 123 Gene3D G3DSA:1.10.10.810 1 115 8.4E-50 T 11-10-2018 UP12_08555 e9bcd53e6a489eba93e5cb31574b28bb 123 Pfam PF08818 Domain of unknown function (DU1801) 18 110 1.4E-12 T 11-10-2018 IPR014922 Domain of unknown function DUF1801 UP12_08555 e9bcd53e6a489eba93e5cb31574b28bb 123 SUPERFAMILY SSF159888 1 123 3.4E-40 T 11-10-2018 UP12_19035 46514ee7a4f937d24b28d04ce5536194 312 Pfam PF09991 Predicted membrane protein (DUF2232) 16 301 9.7E-75 T 11-10-2018 IPR018710 Protein of unknown function DUF2232 UP12_19035 46514ee7a4f937d24b28d04ce5536194 312 Gene3D G3DSA:1.10.1760.20 3 141 8.6E-7 T 11-10-2018 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 SUPERFAMILY SSF47384 222 304 5.49E-16 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 Gene3D G3DSA:1.10.8.500 185 233 9.6E-8 T 11-10-2018 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 455 1.1E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 SUPERFAMILY SSF55874 294 455 1.44E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 SMART SM00304 186 238 4.4E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 SUPERFAMILY SSF158472 186 235 1.16E-9 T 11-10-2018 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 Gene3D G3DSA:1.10.287.130 234 303 1.5E-15 T 11-10-2018 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 304 4.0E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 Pfam PF00672 HAMP domain 186 234 2.2E-8 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 Gene3D G3DSA:3.30.565.10 304 455 7.2E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 SMART SM00387 348 456 5.2E-29 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_18755 333b4bd524c324a9d5e8ef4f340a58fa 456 SMART SM00388 239 304 3.8E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 Gene3D G3DSA:3.20.20.80 3 487 1.1E-147 T 11-10-2018 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 11-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 SUPERFAMILY SSF51445 5 484 1.75E-158 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 Pfam PF00232 Glycosyl hydrolase family 1 6 484 1.8E-131 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 449 461 1.0E-13 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 424 441 1.0E-13 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 403 414 1.0E-13 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 317 331 1.0E-13 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 PRINTS PR00131 Glycosyl hydrolase family 1 signature 382 390 1.0E-13 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18620 aa30e9ce9e4745a3dda7568ad8c80d4a 488 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 382 390 - T 11-10-2018 IPR018120 Glycoside hydrolase family 1, active site UP12_16395 98ddcc57c1dc786b0c3eb80d3b0ca0e4 843 Gene3D G3DSA:3.50.30.10 732 840 8.3E-33 T 11-10-2018 UP12_16395 98ddcc57c1dc786b0c3eb80d3b0ca0e4 843 SUPERFAMILY SSF56059 11 298 1.05E-69 T 11-10-2018 UP12_16395 98ddcc57c1dc786b0c3eb80d3b0ca0e4 843 SUPERFAMILY SSF52009 733 835 7.46E-27 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 UP12_16395 98ddcc57c1dc786b0c3eb80d3b0ca0e4 843 Pfam PF00391 PEP-utilising enzyme, mobile domain 761 832 1.0E-21 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 UP12_16395 98ddcc57c1dc786b0c3eb80d3b0ca0e4 843 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 15 300 2.1E-76 T 11-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 UP12_16395 98ddcc57c1dc786b0c3eb80d3b0ca0e4 843 Gene3D G3DSA:3.30.470.20 165 312 2.4E-39 T 11-10-2018 UP12_16395 98ddcc57c1dc786b0c3eb80d3b0ca0e4 843 Gene3D G3DSA:3.30.1490.20 3 163 4.7E-39 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SMART SM00896 710 803 2.8E-45 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SUPERFAMILY SSF55681 475 694 1.74E-49 T 11-10-2018 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SMART SM00874 411 479 5.3E-32 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Gene3D G3DSA:3.30.56.10 4 189 1.9E-69 T 11-10-2018 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 803 1.8E-268 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SUPERFAMILY SSF54991 705 803 1.44E-31 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Gene3D G3DSA:3.30.930.10 495 698 1.3E-59 T 11-10-2018 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Gene3D G3DSA:2.40.50.140 40 161 1.9E-69 T 11-10-2018 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 46.198 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SUPERFAMILY SSF46955 411 483 1.65E-22 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SMART SM00873 221 394 1.3E-84 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Gene3D G3DSA:3.30.70.380 711 803 7.1E-31 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SUPERFAMILY SSF56037 210 405 3.92E-69 T 11-10-2018 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Pfam PF03484 tRNA synthetase B5 domain 414 479 7.4E-23 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 SUPERFAMILY SSF50249 36 200 1.27E-48 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Gene3D G3DSA:3.50.40.10 204 405 2.7E-81 T 11-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Gene3D G3DSA:3.30.56.10 410 483 1.2E-27 T 11-10-2018 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Pfam PF03483 B3/4 domain 222 394 8.6E-63 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Pfam PF01588 Putative tRNA binding domain 46 152 6.8E-28 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 UP12_12915 ccbe2ca9945238237fd9039d6d5c1bbe 804 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 803 7.3E-29 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 UP12_08950 2bd9ee7fc9d291d0e178a64d4424ed27 90 Pfam PF10852 Protein of unknown function (DUF2651) 11 87 1.7E-25 T 11-10-2018 IPR020258 Uncharacterised protein family YbeF UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 Gene3D G3DSA:3.40.50.720 5 189 1.4E-67 T 11-10-2018 UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 184 3.1E-63 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 184 209 - T 11-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 PIRSF PIRSF000105 2 287 1.3E-88 T 11-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 Gene3D G3DSA:1.10.1040.10 190 287 3.4E-34 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 SUPERFAMILY SSF51735 3 186 7.48E-55 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 283 3.0E-34 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_17390 b1fb69c0d9f80b12f632dfb7931b92c0 287 SUPERFAMILY SSF48179 186 285 1.28E-33 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_11070 3922e379aa9c2630a26cfcf40ffd6c51 175 Pfam PF11085 Conserved membrane protein YqhR 5 168 1.1E-76 T 11-10-2018 IPR024563 Uncharacterised protein family YqhR UP12_11070 3922e379aa9c2630a26cfcf40ffd6c51 175 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 20 160 4.0E-48 T 11-10-2018 IPR024563 Uncharacterised protein family YqhR UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 Pfam PF07690 Major Facilitator Superfamily 34 399 5.9E-55 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 SUPERFAMILY SSF103473 9 436 3.92E-83 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 TIGRFAM TIGR00712 glpT: glycerol-3-phosphate transporter 1 440 1.2E-248 T 11-10-2018 IPR005267 Glycerol-3-phosphate transporter GO:0015169|GO:0015794|GO:0016021 UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 PIRSF PIRSF002808 5 444 1.7E-172 T 11-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 ProSitePatterns PS00942 glpT family of transporters signature. 153 169 - T 11-10-2018 IPR021159 Glycerate/sugar phosphate transporter, conserved site Reactome: R-HSA-3229133|Reactome: R-HSA-70263 UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 TIGRFAM TIGR00881 2A0104: phosphoglycerate transporter family protein 35 417 1.5E-164 T 11-10-2018 UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 Gene3D G3DSA:1.20.1250.20 19 226 2.5E-57 T 11-10-2018 UP12_01230 a121efe26536c1841afdecac3a3d5f22 444 Gene3D G3DSA:1.20.1250.20 240 442 2.6E-56 T 11-10-2018 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 PIRSF PIRSF001399 1 145 2.3E-63 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 142 8.0E-61 T 11-10-2018 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 Gene3D G3DSA:3.40.50.9100 2 144 2.9E-66 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 Pfam PF01220 Dehydroquinase class II 4 139 1.8E-62 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 141 1.1E-67 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 SUPERFAMILY SSF52304 4 141 1.44E-59 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 11-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_11065 834d3de9d5c14cf3c78eed6e24f8b82d 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 67.59 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 UP12_00345 0739483bb1f39435f232ef83e46301a2 178 SMART SM00966 8 52 1.1E-10 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_00345 0739483bb1f39435f232ef83e46301a2 178 PIRSF PIRSF026579 1 178 2.9E-95 T 11-10-2018 IPR014213 Sporulation stage V, protein T UP12_00345 0739483bb1f39435f232ef83e46301a2 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_00345 0739483bb1f39435f232ef83e46301a2 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_00345 0739483bb1f39435f232ef83e46301a2 178 Gene3D G3DSA:3.30.450.40 56 178 8.0E-48 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_00345 0739483bb1f39435f232ef83e46301a2 178 Gene3D G3DSA:2.10.260.10 1 49 3.8E-24 T 11-10-2018 UP12_00345 0739483bb1f39435f232ef83e46301a2 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 5.8E-47 T 11-10-2018 IPR039472 Sporulation stage V protein T, GAF domain UP12_00345 0739483bb1f39435f232ef83e46301a2 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily UP12_00345 0739483bb1f39435f232ef83e46301a2 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 2.3E-89 T 11-10-2018 IPR014213 Sporulation stage V, protein T UP12_12515 fc5b31f8a6adbda315406c270641a72c 197 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 193 2.0E-66 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 UP12_12515 fc5b31f8a6adbda315406c270641a72c 197 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 195 48.88 T 11-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 UP12_12515 fc5b31f8a6adbda315406c270641a72c 197 Gene3D G3DSA:3.90.950.10 1 197 9.5E-77 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UP12_12515 fc5b31f8a6adbda315406c270641a72c 197 Pfam PF01725 Ham1 family 5 190 3.0E-60 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 UP12_12515 fc5b31f8a6adbda315406c270641a72c 197 SUPERFAMILY SSF52972 2 193 6.54E-70 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 Gene3D G3DSA:1.10.1040.10 164 295 3.0E-35 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 5.4E-33 T 11-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 SUPERFAMILY SSF51735 3 163 9.86E-49 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 Gene3D G3DSA:3.40.50.720 1 163 5.7E-58 T 11-10-2018 UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 6.9E-52 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 PIRSF PIRSF000103 1 295 8.3E-81 T 11-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 294 3.1E-113 T 11-10-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 SUPERFAMILY SSF48179 166 293 1.25E-33 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_18260 ed679b3172a99ad0dea669fc200ac984 297 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 11-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 Gene3D G3DSA:3.90.190.20 339 490 5.6E-59 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 SUPERFAMILY SSF63418 10 99 5.89E-25 T 11-10-2018 IPR035911 MurE/MurF, N-terminal UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 Pfam PF08245 Mur ligase middle domain 108 313 1.2E-56 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 Pfam PF01225 Mur ligase family, catalytic domain 24 96 2.1E-15 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 106 130 - T 11-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 Gene3D G3DSA:3.40.1390.10 2 98 3.5E-28 T 11-10-2018 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 485 36.276 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 485 3.1E-179 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 Pfam PF02875 Mur ligase family, glutamate ligase domain 334 419 1.3E-24 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 SUPERFAMILY SSF53244 334 487 6.41E-48 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 Gene3D G3DSA:3.40.1190.10 99 338 3.6E-90 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_07360 a232bbad128f1cbdfd2ef031bca93c0c 491 SUPERFAMILY SSF53623 99 333 2.35E-75 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_13755 2951fd48c1c2241e7bbba452ce111af8 264 Gene3D G3DSA:3.40.50.1820 19 260 6.6E-45 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13755 2951fd48c1c2241e7bbba452ce111af8 264 SUPERFAMILY SSF53474 9 255 1.31E-48 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13755 2951fd48c1c2241e7bbba452ce111af8 264 Pfam PF00326 Prolyl oligopeptidase family 64 255 6.0E-24 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UP12_13755 2951fd48c1c2241e7bbba452ce111af8 264 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 97 127 - T 11-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 230 1.7E-66 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 Gene3D G3DSA:1.20.1080.10 1 241 3.1E-75 T 11-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 ProSitePatterns PS00221 MIP family signature. 62 70 - T 11-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 PRINTS PR00783 Major intrinsic protein family signature 44 68 1.2E-49 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 PRINTS PR00783 Major intrinsic protein family signature 166 188 1.2E-49 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 PRINTS PR00783 Major intrinsic protein family signature 2 21 1.2E-49 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 PRINTS PR00783 Major intrinsic protein family signature 81 100 1.2E-49 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 PRINTS PR00783 Major intrinsic protein family signature 213 233 1.2E-49 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 PRINTS PR00783 Major intrinsic protein family signature 136 154 1.2E-49 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 SUPERFAMILY SSF81338 2 234 1.03E-70 T 11-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 UP12_04790 ae2ca8e389f6827cc932d15c89b4f475 271 Pfam PF00230 Major intrinsic protein 6 230 6.4E-50 T 11-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 Gene3D G3DSA:1.20.1530.20 3 399 4.1E-69 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 SUPERFAMILY SSF116726 541 609 4.84E-8 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 Gene3D G3DSA:3.30.70.1450 535 613 6.2E-16 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 Pfam PF02254 TrkA-N domain 406 516 7.9E-10 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 Pfam PF00999 Sodium/hydrogen exchanger family 10 393 1.3E-75 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 Pfam PF02080 TrkA-C domain 553 610 6.1E-9 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 Gene3D G3DSA:3.40.50.720 400 534 6.9E-15 T 11-10-2018 UP12_05805 322e2eb7a8186d3b4f9130913e92c341 613 SUPERFAMILY SSF51735 403 517 7.09E-12 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06805 228073bc88f8b77d7d6cb790e8116843 285 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 24 0.0016 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UP12_06805 228073bc88f8b77d7d6cb790e8116843 285 Pfam PF00149 Calcineurin-like phosphoesterase 58 222 1.9E-11 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_06805 228073bc88f8b77d7d6cb790e8116843 285 SUPERFAMILY SSF56300 58 282 2.53E-32 T 11-10-2018 UP12_06805 228073bc88f8b77d7d6cb790e8116843 285 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 3 26 2.2E-5 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal UP12_06805 228073bc88f8b77d7d6cb790e8116843 285 Gene3D G3DSA:3.60.21.10 56 244 5.4E-22 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 PIRSF PIRSF000193 1 268 1.4E-74 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 SUPERFAMILY SSF51735 3 159 6.5E-32 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 Gene3D G3DSA:3.40.50.720 1 162 3.4E-48 T 11-10-2018 UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 SUPERFAMILY SSF48179 160 268 1.12E-30 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 Gene3D G3DSA:1.10.3730.10 163 270 3.5E-36 T 11-10-2018 UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 98 6.3E-20 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 265 7.8E-80 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 265 7.1E-32 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_10720 cdf1df83a45dacf99a2ad519b6c79424 275 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 265 25.385 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_13850 2bab22a8aad40d9f0b005cfae5ccace2 188 Gene3D G3DSA:3.40.1050.10 2 183 3.6E-45 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UP12_13850 2bab22a8aad40d9f0b005cfae5ccace2 188 SMART SM00947 26 182 3.8E-38 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UP12_13850 2bab22a8aad40d9f0b005cfae5ccace2 188 SUPERFAMILY SSF53056 1 181 2.09E-41 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UP12_13850 2bab22a8aad40d9f0b005cfae5ccace2 188 Pfam PF00484 Carbonic anhydrase 33 178 8.8E-18 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UP12_13725 b58bee2c6bbccea88371542d627749bf 259 Gene3D G3DSA:3.40.50.1820 1 258 8.1E-52 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13725 b58bee2c6bbccea88371542d627749bf 259 Pfam PF12146 Serine aminopeptidase, S33 8 243 2.1E-57 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 UP12_13725 b58bee2c6bbccea88371542d627749bf 259 SUPERFAMILY SSF53474 7 256 7.83E-36 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13725 b58bee2c6bbccea88371542d627749bf 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 4.2E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_13725 b58bee2c6bbccea88371542d627749bf 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 4.2E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_13725 b58bee2c6bbccea88371542d627749bf 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 4.2E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_16430 69284693e5f03f7bc007bd04c27d4d51 224 SUPERFAMILY SSF55469 11 222 3.66E-55 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_16430 69284693e5f03f7bc007bd04c27d4d51 224 Pfam PF00881 Nitroreductase family 16 202 2.0E-26 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UP12_16430 69284693e5f03f7bc007bd04c27d4d51 224 Gene3D G3DSA:3.40.109.10 2 224 2.8E-60 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_13080 3ed3caf0f16651a3708298f4b032c0df 423 Gene3D G3DSA:3.40.718.10 1 423 1.1E-183 T 11-10-2018 UP12_13080 3ed3caf0f16651a3708298f4b032c0df 423 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UP12_13080 3ed3caf0f16651a3708298f4b032c0df 423 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 422 4.5E-225 T 11-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 UP12_13080 3ed3caf0f16651a3708298f4b032c0df 423 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 4.7E-125 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UP12_13080 3ed3caf0f16651a3708298f4b032c0df 423 SMART SM01329 21 418 1.1E-186 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UP12_13080 3ed3caf0f16651a3708298f4b032c0df 423 SUPERFAMILY SSF53659 3 422 2.69E-142 T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 12 217 1.9E-26 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 Gene3D G3DSA:3.40.50.1000 175 244 3.9E-35 T 11-10-2018 IPR023214 HAD superfamily UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 Gene3D G3DSA:3.40.50.1000 11 88 2.0E-24 T 11-10-2018 IPR023214 HAD superfamily UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 Gene3D G3DSA:3.30.1240.10 89 116 2.0E-24 T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 Gene3D G3DSA:3.30.1240.10 129 174 3.9E-35 T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 ProSitePatterns PS01228 Hypothetical cof family signature 1. 12 23 - T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 198 217 1.2E-5 T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 221 233 1.2E-5 T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 14 28 1.2E-5 T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 SUPERFAMILY SSF56784 7 249 1.07E-65 T 11-10-2018 IPR036412 HAD-like superfamily UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 ProSitePatterns PS01229 Hypothetical cof family signature 2. 198 220 - T 11-10-2018 UP12_02245 1bc1c8399944ac51c51a53982bb5b365 251 Pfam PF08282 haloacid dehalogenase-like hydrolase 128 244 9.5E-31 T 11-10-2018 UP12_15415 e1ab564422757ab991d7b30a722c746a 341 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_15415 e1ab564422757ab991d7b30a722c746a 341 SUPERFAMILY SSF55021 249 340 1.72E-25 T 11-10-2018 UP12_15415 e1ab564422757ab991d7b30a722c746a 341 Gene3D G3DSA:3.40.50.300 1 246 3.6E-75 T 11-10-2018 UP12_15415 e1ab564422757ab991d7b30a722c746a 341 SMART SM00382 30 218 2.5E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15415 e1ab564422757ab991d7b30a722c746a 341 Gene3D G3DSA:3.30.70.260 247 340 2.1E-32 T 11-10-2018 UP12_15415 e1ab564422757ab991d7b30a722c746a 341 Pfam PF00005 ABC transporter 21 169 3.0E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15415 e1ab564422757ab991d7b30a722c746a 341 Pfam PF09383 NIL domain 265 337 4.1E-23 T 11-10-2018 IPR018449 NIL domain UP12_15415 e1ab564422757ab991d7b30a722c746a 341 SMART SM00930 263 338 9.6E-33 T 11-10-2018 IPR018449 NIL domain UP12_15415 e1ab564422757ab991d7b30a722c746a 341 SUPERFAMILY SSF52540 1 240 1.43E-81 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 148 159 5.4E-9 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 5.4E-9 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 109 120 5.4E-9 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 139 147 5.4E-9 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 Gene3D G3DSA:3.30.930.10 6 285 3.2E-101 T 11-10-2018 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 104 273 6.1E-16 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 Gene3D G3DSA:3.30.110.30 404 477 8.9E-24 T 11-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 Gene3D G3DSA:3.40.50.800 286 401 1.8E-33 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 SUPERFAMILY SSF55681 14 279 8.96E-76 T 11-10-2018 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 SUPERFAMILY SSF64586 406 477 2.35E-21 T 11-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 411 477 3.6E-24 T 11-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 12 477 1.2E-178 T 11-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 Pfam PF03129 Anticodon binding domain 292 382 4.1E-19 T 11-10-2018 IPR004154 Anticodon-binding UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 SUPERFAMILY SSF52954 281 401 5.07E-32 T 11-10-2018 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 SMART SM00946 410 477 7.7E-30 T 11-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 UP12_01315 0eb6f6d230928a4ecdf6dc5c39f9d4f6 477 Hamap MF_01571 Proline--tRNA ligase [proS]. 10 477 43.168 T 11-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 UP12_11915 c1fe61963a369f38d4f4dda0062e2306 580 Pfam PF03717 Penicillin-binding Protein dimerisation domain 61 215 1.8E-9 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UP12_11915 c1fe61963a369f38d4f4dda0062e2306 580 SUPERFAMILY SSF56601 184 573 4.66E-59 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_11915 c1fe61963a369f38d4f4dda0062e2306 580 SUPERFAMILY SSF56519 50 219 6.28E-20 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UP12_11915 c1fe61963a369f38d4f4dda0062e2306 580 Gene3D G3DSA:3.40.710.10 233 580 1.4E-67 T 11-10-2018 UP12_11915 c1fe61963a369f38d4f4dda0062e2306 580 Gene3D G3DSA:3.90.1310.30 50 228 4.2E-16 T 11-10-2018 UP12_11915 c1fe61963a369f38d4f4dda0062e2306 580 Pfam PF00905 Penicillin binding protein transpeptidase domain 259 569 7.1E-53 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_15880 2d80eb67e842de1bf4d846105b9eddba 153 Pfam PF00583 Acetyltransferase (GNAT) family 33 115 3.7E-14 T 11-10-2018 IPR000182 GNAT domain UP12_15880 2d80eb67e842de1bf4d846105b9eddba 153 SUPERFAMILY SSF55729 8 149 8.1E-30 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_15880 2d80eb67e842de1bf4d846105b9eddba 153 Gene3D G3DSA:3.40.630.30 1 152 4.7E-46 T 11-10-2018 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 642 7.9E-242 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Gene3D G3DSA:3.10.20.30 2 66 2.2E-24 T 11-10-2018 IPR012675 Beta-grasp domain superfamily UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Gene3D G3DSA:3.30.980.10 72 227 2.3E-63 T 11-10-2018 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Gene3D G3DSA:3.40.50.800 544 646 1.0E-32 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Pfam PF02824 TGS domain 7 64 8.3E-12 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 SUPERFAMILY SSF52954 540 643 4.23E-29 T 11-10-2018 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Pfam PF03129 Anticodon binding domain 552 638 3.0E-23 T 11-10-2018 IPR004154 Anticodon-binding UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 SUPERFAMILY SSF55186 67 246 1.96E-64 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 SMART SM00863 175 224 9.4E-25 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 SUPERFAMILY SSF55681 248 537 2.99E-97 T 11-10-2018 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Gene3D G3DSA:3.30.54.20 136 192 2.3E-63 T 11-10-2018 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 329 540 2.9E-35 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 518 531 1.8E-47 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 336 364 1.8E-47 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 545 557 1.8E-47 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 369 392 1.8E-47 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 PRINTS PR01047 Threonyl-tRNA synthetase signature 475 503 1.8E-47 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 646 35.43 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 SUPERFAMILY SSF81271 5 64 6.76E-15 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Gene3D G3DSA:3.30.930.10 230 543 3.1E-117 T 11-10-2018 UP12_13000 f5d2d50f398185e23f7d923994273c1a 646 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 175 224 2.8E-16 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 2.6E-46 T 11-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 PIRSF PIRSF000445 1 434 7.8E-156 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 29.938 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 Gene3D G3DSA:3.40.50.720 161 313 9.6E-47 T 11-10-2018 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 Gene3D G3DSA:3.30.460.30 1 158 9.6E-55 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 419 1.1E-19 T 11-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 11-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 SUPERFAMILY SSF69742 1 158 8.37E-47 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 SUPERFAMILY SSF69075 318 419 6.67E-16 T 11-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 1.0E-47 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase UP12_12360 26fd36084bc76083744f0da812e7ea15 455 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 419 4.5E-165 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 UP12_12360 26fd36084bc76083744f0da812e7ea15 455 SUPERFAMILY SSF51735 162 314 2.95E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 Pfam PF00672 HAMP domain 214 262 2.6E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 420 2.6E-20 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 422 451 2.6E-20 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 19 44 2.6E-20 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 SMART SM00304 214 266 3.0E-15 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 Gene3D G3DSA:1.20.1480.50 179 272 1.2E-15 T 11-10-2018 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 Gene3D G3DSA:1.10.287.950 273 570 1.3E-64 T 11-10-2018 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 SUPERFAMILY SSF58104 234 570 6.15E-66 T 11-10-2018 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 342 523 4.9E-42 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_03945 45f05a72636f59fc1820a1a7be5a0fc9 574 SMART SM00283 295 570 3.5E-69 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 165 3.1E-29 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 SUPERFAMILY SSF88659 84 165 1.29E-16 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 Pfam PF08281 Sigma-70, region 4 109 161 1.5E-14 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 Pfam PF04542 Sigma-70 region 2 11 76 2.3E-13 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 SUPERFAMILY SSF88946 7 91 7.85E-20 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 Gene3D G3DSA:1.10.1740.10 1 78 1.5E-21 T 11-10-2018 UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 7 165 2.2E-52 T 11-10-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_07125 d975c4f0358d2fc202cbf61b5fdcbcd6 172 Gene3D G3DSA:1.10.10.10 85 168 2.1E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06840 dd9a3d2f8f5ee0e26f9954e624e07418 147 SUPERFAMILY SSF54631 13 139 1.17E-27 T 11-10-2018 UP12_06840 dd9a3d2f8f5ee0e26f9954e624e07418 147 Gene3D G3DSA:3.10.580.10 1 147 2.0E-57 T 11-10-2018 UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 Pfam PF01268 Formate--tetrahydrofolate ligase 7 560 1.4E-266 T 11-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 5 560 48.455 T 11-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 SUPERFAMILY SSF52540 8 558 4.83E-241 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 Gene3D G3DSA:3.10.410.10 447 536 2.3E-35 T 11-10-2018 UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 332 343 - T 11-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 Gene3D G3DSA:3.30.1510.10 133 251 2.3E-202 T 11-10-2018 UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 Gene3D G3DSA:3.40.50.300 10 442 2.3E-202 T 11-10-2018 UP12_09830 826f51b1952580be875c8b25fcaa69fb 560 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 107 117 - T 11-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 UP12_07990 69415385f140faf500d7083d0bef5981 677 PIRSF PIRSF005419 1 677 2.1E-262 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_07990 69415385f140faf500d7083d0bef5981 677 Gene3D G3DSA:1.10.490.80 577 675 8.7E-30 T 11-10-2018 UP12_07990 69415385f140faf500d7083d0bef5981 677 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 11-10-2018 IPR025505 FHIPEP conserved site UP12_07990 69415385f140faf500d7083d0bef5981 677 Gene3D G3DSA:1.10.8.540 486 575 1.4E-33 T 11-10-2018 UP12_07990 69415385f140faf500d7083d0bef5981 677 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 675 4.8E-283 T 11-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 UP12_07990 69415385f140faf500d7083d0bef5981 677 Gene3D G3DSA:3.40.30.60 342 485 8.3E-54 T 11-10-2018 UP12_07990 69415385f140faf500d7083d0bef5981 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 2.1E-54 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_07990 69415385f140faf500d7083d0bef5981 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 2.1E-54 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_07990 69415385f140faf500d7083d0bef5981 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 2.1E-54 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_07990 69415385f140faf500d7083d0bef5981 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 2.1E-54 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_07990 69415385f140faf500d7083d0bef5981 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 2.1E-54 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_07990 69415385f140faf500d7083d0bef5981 677 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 2.1E-54 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_07990 69415385f140faf500d7083d0bef5981 677 Pfam PF00771 FHIPEP family 15 667 1.8E-276 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 Gene3D G3DSA:2.40.50.140 1 66 3.4E-30 T 11-10-2018 UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 PIRSF PIRSF002599 1 67 9.7E-25 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 SUPERFAMILY SSF50249 1 65 3.05E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 SMART SM00357 3 66 2.2E-31 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 PRINTS PR00050 Cold shock protein signature 39 57 1.8E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 PRINTS PR00050 Cold shock protein signature 24 33 1.8E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 PRINTS PR00050 Cold shock protein signature 4 19 1.8E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 11-10-2018 IPR019844 Cold-shock conserved site UP12_02850 08cd0a355f502fa74bd52c3e76059455 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.2E-31 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 218 1.9E-57 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 245 16.693 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 223 3.2E-69 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 151 179 2.1E-40 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 81 99 2.1E-40 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 2.1E-40 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 99 125 2.1E-40 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 UP12_03165 387110f23c05883a9d82ddec5bb71b65 251 ProSitePatterns PS01218 TatC family signature. 151 170 - T 11-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 2 402 2.5E-232 T 11-10-2018 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 Gene3D G3DSA:3.40.50.720 187 350 1.8E-134 T 11-10-2018 UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 Gene3D G3DSA:3.90.180.10 44 387 1.8E-134 T 11-10-2018 UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 76 90 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 Pfam PF00107 Zinc-binding dehydrogenase 206 275 2.7E-11 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 44 153 8.0E-26 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 SUPERFAMILY SSF50129 4 199 2.93E-57 T 11-10-2018 IPR011032 GroES-like superfamily UP12_11870 d2ce6c59ae7d87cc00dd05f4315f2052 404 SUPERFAMILY SSF51735 172 362 2.04E-64 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08990 96501a8eb6f501d3d58bceae76399f4e 486 Gene3D G3DSA:3.40.309.10 254 454 1.0E-157 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_08990 96501a8eb6f501d3d58bceae76399f4e 486 Pfam PF00171 Aldehyde dehydrogenase family 17 481 2.7E-154 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_08990 96501a8eb6f501d3d58bceae76399f4e 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UP12_08990 96501a8eb6f501d3d58bceae76399f4e 486 Hamap MF_01670 Malonate-semialdehyde dehydrogenase [iolA]. 3 485 73.804 T 11-10-2018 IPR023510 Methylmalonate-semialdehyde dehydrogenase, Gram-positive bacteria GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642 UP12_08990 96501a8eb6f501d3d58bceae76399f4e 486 Gene3D G3DSA:3.40.605.10 24 462 1.0E-157 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_08990 96501a8eb6f501d3d58bceae76399f4e 486 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 10 485 7.9E-182 T 11-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 UP12_08990 96501a8eb6f501d3d58bceae76399f4e 486 SUPERFAMILY SSF53720 6 484 1.31E-152 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 SMART SM00138 1 255 2.6E-112 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 Pfam PF03705 CheR methyltransferase, all-alpha domain 4 54 8.0E-11 T 11-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 SUPERFAMILY SSF47757 3 66 6.67E-10 T 11-10-2018 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 SUPERFAMILY SSF53335 67 240 5.46E-48 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 1.7E-39 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 PRINTS PR00996 Glutamate methyltransferase family signature 215 238 1.7E-39 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 1.7E-39 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 1.7E-39 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 PRINTS PR00996 Glutamate methyltransferase family signature 23 36 1.7E-39 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 PRINTS PR00996 Glutamate methyltransferase family signature 196 210 1.7E-39 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 251 5.7E-64 T 11-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal UP12_10200 18893e2a55ea7a210a70e35958c9add1 259 Gene3D G3DSA:3.40.50.150 66 257 1.7E-69 T 11-10-2018 UP12_09705 eb485454b361f089a4b4c89f005848b6 143 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 5 135 1.3E-65 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UP12_09705 eb485454b361f089a4b4c89f005848b6 143 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 127 37.736 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UP12_09705 eb485454b361f089a4b4c89f005848b6 143 SUPERFAMILY SSF51316 3 142 3.82E-60 T 11-10-2018 IPR011057 Mss4-like superfamily UP12_09705 eb485454b361f089a4b4c89f005848b6 143 Gene3D G3DSA:2.170.150.20 1 143 1.1E-60 T 11-10-2018 UP12_09705 eb485454b361f089a4b4c89f005848b6 143 Pfam PF01641 SelR domain 10 126 1.1E-48 T 11-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 UP12_03660 027395af7cf4bc1f73800b25fc1a490a 145 Pfam PF02082 Transcriptional regulator 1 83 2.4E-25 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_03660 027395af7cf4bc1f73800b25fc1a490a 145 SUPERFAMILY SSF46785 2 135 9.95E-30 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03660 027395af7cf4bc1f73800b25fc1a490a 145 Gene3D G3DSA:1.10.10.10 1 144 4.3E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03660 027395af7cf4bc1f73800b25fc1a490a 145 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 2.6E-34 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_03660 027395af7cf4bc1f73800b25fc1a490a 145 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 11-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site UP12_18670 15d0afb9337a3c472639302634f9cc00 339 Gene3D G3DSA:1.10.260.40 1 65 2.6E-20 T 11-10-2018 UP12_18670 15d0afb9337a3c472639302634f9cc00 339 SMART SM00354 8 78 3.2E-29 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_18670 15d0afb9337a3c472639302634f9cc00 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 53 4.1E-16 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_18670 15d0afb9337a3c472639302634f9cc00 339 SUPERFAMILY SSF53822 68 337 1.45E-74 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_18670 15d0afb9337a3c472639302634f9cc00 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 11-10-2018 UP12_18670 15d0afb9337a3c472639302634f9cc00 339 Pfam PF13377 Periplasmic binding protein-like domain 176 336 1.0E-32 T 11-10-2018 UP12_18670 15d0afb9337a3c472639302634f9cc00 339 Gene3D G3DSA:3.40.50.2300 69 329 2.1E-76 T 11-10-2018 UP12_18670 15d0afb9337a3c472639302634f9cc00 339 SUPERFAMILY SSF47413 7 66 1.56E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_18670 15d0afb9337a3c472639302634f9cc00 339 Gene3D G3DSA:3.40.50.2300 168 334 2.1E-76 T 11-10-2018 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 SUPERFAMILY SSF53067 3 140 7.92E-39 T 11-10-2018 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 SUPERFAMILY SSF53067 142 325 9.26E-51 T 11-10-2018 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 Pfam PF06723 MreB/Mbl protein 4 327 3.0E-150 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 2 327 2.2E-136 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 Gene3D G3DSA:3.90.640.10 178 251 1.6E-127 T 11-10-2018 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 41 59 1.1E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 292 318 1.1E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 61 84 1.1E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 179 199 1.1E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 124 143 1.1E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 Gene3D G3DSA:3.30.420.40 146 309 1.6E-127 T 11-10-2018 UP12_17010 f17c046cf2fef7a5fa4da90aa506d745 333 Gene3D G3DSA:3.30.420.40 6 319 1.6E-127 T 11-10-2018 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 PIRSF PIRSF000478 1 432 6.7E-171 T 11-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 5.1E-22 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 1.2E-182 T 11-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 11-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 Gene3D G3DSA:1.20.970.10 1 67 4.1E-30 T 11-10-2018 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 SUPERFAMILY SSF54680 331 431 2.62E-29 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 Gene3D G3DSA:3.90.1170.30 335 423 5.4E-35 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 5.8E-27 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 3.4E-49 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 Gene3D G3DSA:3.40.1030.10 69 334 1.4E-118 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 SUPERFAMILY SSF52418 69 329 3.66E-92 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 SUPERFAMILY SSF47648 1 69 1.11E-22 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_18365 62736755f7d5c170446ecc00dc3d2381 433 SMART SM00941 345 418 1.9E-32 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_05875 10518f348b681963d3757141c72358f8 128 Pfam PF07552 Spore Coat Protein X and V domain 6 63 8.1E-17 T 11-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 UP12_05875 10518f348b681963d3757141c72358f8 128 Pfam PF07552 Spore Coat Protein X and V domain 71 127 1.4E-14 T 11-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 UP12_03420 cdb3b0e94a9b491a3e43da6d589e3284 221 Pfam PF01144 Coenzyme A transferase 11 205 6.7E-33 T 11-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 UP12_03420 cdb3b0e94a9b491a3e43da6d589e3284 221 SUPERFAMILY SSF100950 7 218 2.58E-65 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_03420 cdb3b0e94a9b491a3e43da6d589e3284 221 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 9 212 2.8E-86 T 11-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 UP12_03420 cdb3b0e94a9b491a3e43da6d589e3284 221 SMART SM00882 10 206 3.0E-58 T 11-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 UP12_03420 cdb3b0e94a9b491a3e43da6d589e3284 221 Gene3D G3DSA:3.40.1080.10 5 218 3.3E-85 T 11-10-2018 UP12_05000 dfcbb9e38afb05ee821272df39f47469 288 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 268 4.8E-49 T 11-10-2018 UP12_05000 dfcbb9e38afb05ee821272df39f47469 288 SUPERFAMILY SSF56784 3 273 1.35E-53 T 11-10-2018 IPR036412 HAD-like superfamily UP12_05000 dfcbb9e38afb05ee821272df39f47469 288 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 268 5.8E-44 T 11-10-2018 IPR000150 Cof family GO:0016787 UP12_05000 dfcbb9e38afb05ee821272df39f47469 288 Gene3D G3DSA:3.40.50.1000 5 265 2.1E-79 T 11-10-2018 IPR023214 HAD superfamily UP12_05000 dfcbb9e38afb05ee821272df39f47469 288 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 241 9.0E-15 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_05000 dfcbb9e38afb05ee821272df39f47469 288 Gene3D G3DSA:3.30.1240.10 84 196 2.1E-79 T 11-10-2018 UP12_15690 8c168862672367db72b887003ab57b00 289 ProSitePatterns PS01125 ROK family signature. 130 155 - T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_15690 8c168862672367db72b887003ab57b00 289 Gene3D G3DSA:3.30.420.40 105 289 2.0E-65 T 11-10-2018 UP12_15690 8c168862672367db72b887003ab57b00 289 SUPERFAMILY SSF53067 1 285 6.76E-49 T 11-10-2018 UP12_15690 8c168862672367db72b887003ab57b00 289 Pfam PF00480 ROK family 4 284 1.9E-72 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_15690 8c168862672367db72b887003ab57b00 289 Gene3D G3DSA:3.30.420.40 1 104 2.4E-30 T 11-10-2018 UP12_06315 798696d4f539344ae5270c6b72e07104 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 298 3.5E-16 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_06315 798696d4f539344ae5270c6b72e07104 322 SUPERFAMILY SSF52540 6 251 6.9E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06315 798696d4f539344ae5270c6b72e07104 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 318 4.4E-28 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_06315 798696d4f539344ae5270c6b72e07104 322 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_06315 798696d4f539344ae5270c6b72e07104 322 Gene3D G3DSA:3.40.50.300 4 322 1.2E-104 T 11-10-2018 UP12_06315 798696d4f539344ae5270c6b72e07104 322 Pfam PF00005 ABC transporter 27 179 1.1E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_06315 798696d4f539344ae5270c6b72e07104 322 SMART SM00382 36 229 8.4E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_03425 50d9a19299a39809780baab1c068a6c7 421 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 95 104 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 UP12_03425 50d9a19299a39809780baab1c068a6c7 421 Pfam PF07687 Peptidase dimerisation domain 201 312 1.0E-15 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain UP12_03425 50d9a19299a39809780baab1c068a6c7 421 Gene3D G3DSA:3.40.630.10 26 417 1.4E-141 T 11-10-2018 UP12_03425 50d9a19299a39809780baab1c068a6c7 421 Gene3D G3DSA:3.30.70.360 203 329 1.4E-141 T 11-10-2018 UP12_03425 50d9a19299a39809780baab1c068a6c7 421 Pfam PF01546 Peptidase family M20/M25/M40 96 413 1.1E-40 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_03425 50d9a19299a39809780baab1c068a6c7 421 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 19 408 3.0E-112 T 11-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase UP12_03425 50d9a19299a39809780baab1c068a6c7 421 SUPERFAMILY SSF53187 6 418 3.55E-67 T 11-10-2018 UP12_03425 50d9a19299a39809780baab1c068a6c7 421 SUPERFAMILY SSF55031 202 308 9.87E-13 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_13520 10026e2ede2503228adbcbffe7a0e20c 183 SUPERFAMILY SSF55144 6 181 1.1E-39 T 11-10-2018 IPR009097 Cyclic phosphodiesterase UP12_13520 10026e2ede2503228adbcbffe7a0e20c 183 Gene3D G3DSA:3.90.1140.10 1 182 1.4E-40 T 11-10-2018 UP12_13520 10026e2ede2503228adbcbffe7a0e20c 183 Pfam PF13563 2'-5' RNA ligase superfamily 30 145 8.1E-19 T 11-10-2018 UP12_13520 10026e2ede2503228adbcbffe7a0e20c 183 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 5 181 20.424 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 UP12_13520 10026e2ede2503228adbcbffe7a0e20c 183 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 6 181 3.7E-45 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 UP12_07530 7521dc123ec5615de9f67cdd34c537f3 180 Pfam PF00156 Phosphoribosyl transferase domain 7 150 4.8E-20 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UP12_07530 7521dc123ec5615de9f67cdd34c537f3 180 SUPERFAMILY SSF53271 5 173 8.26E-42 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_07530 7521dc123ec5615de9f67cdd34c537f3 180 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 179 38.756 T 11-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UP12_07530 7521dc123ec5615de9f67cdd34c537f3 180 Gene3D G3DSA:3.40.50.2020 1 180 4.1E-60 T 11-10-2018 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 3.9E-40 T 11-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 Gene3D G3DSA:1.10.150.300 113 200 8.3E-159 T 11-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 Pfam PF01926 50S ribosome-binding GTPase 5 126 1.7E-24 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 1.6E-160 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 Gene3D G3DSA:3.40.50.300 4 281 8.3E-159 T 11-10-2018 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 SUPERFAMILY SSF52540 3 304 5.74E-90 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.925 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 Gene3D G3DSA:3.10.20.30 48 364 8.3E-159 T 11-10-2018 IPR012675 Beta-grasp domain superfamily UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 SUPERFAMILY SSF81271 282 363 3.49E-36 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.8E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.8E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.8E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.8E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_19105 f8533e91142bb48a4c0bfeca5757e52f 366 PIRSF PIRSF006641 1 366 7.0E-168 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 UP12_17035 f5c59dd992150200b8c5a52abfed38d4 462 Gene3D G3DSA:1.20.1720.10 11 251 4.1E-40 T 11-10-2018 UP12_17035 f5c59dd992150200b8c5a52abfed38d4 462 SUPERFAMILY SSF103473 4 452 1.7E-63 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_17035 f5c59dd992150200b8c5a52abfed38d4 462 Pfam PF07690 Major Facilitator Superfamily 15 409 6.1E-60 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_17035 f5c59dd992150200b8c5a52abfed38d4 462 Gene3D G3DSA:1.20.1250.20 255 450 3.1E-23 T 11-10-2018 UP12_07575 a6cbbbf0465c76fe7d317564165156be 212 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 212 30.099 T 11-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07575 a6cbbbf0465c76fe7d317564165156be 212 Gene3D G3DSA:3.40.50.2020 1 211 2.7E-63 T 11-10-2018 UP12_07575 a6cbbbf0465c76fe7d317564165156be 212 Pfam PF00156 Phosphoribosyl transferase domain 44 172 6.0E-22 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UP12_07575 a6cbbbf0465c76fe7d317564165156be 212 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 7 177 3.7E-51 T 11-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07575 a6cbbbf0465c76fe7d317564165156be 212 SUPERFAMILY SSF53271 7 205 9.83E-55 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_01765 9f1351bda68a7be8094fccf4bad90ea6 450 PIRSF PIRSF006060 8 448 2.2E-40 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_01765 9f1351bda68a7be8094fccf4bad90ea6 450 Pfam PF00324 Amino acid permease 24 387 2.0E-43 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_01765 9f1351bda68a7be8094fccf4bad90ea6 450 SUPERFAMILY SSF103473 197 444 1.02E-9 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01765 9f1351bda68a7be8094fccf4bad90ea6 450 Gene3D G3DSA:1.20.1740.10 13 450 1.4E-45 T 11-10-2018 UP12_18190 b111d0a8d698b177fc3e8519aa018522 141 Pfam PF16888 Domain of unknown function (DUF5082) 15 103 1.9E-13 T 11-10-2018 IPR031681 Protein of unknown function DUF5082 UP12_18190 b111d0a8d698b177fc3e8519aa018522 141 ProDom PD085159 YWQH COILED COIL 1 138 1.0E-25 T 11-10-2018 IPR020326 Uncharacterised protein family YwqH UP12_00205 60d5a02655ea1f2926180e88860939e9 212 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 31.045 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UP12_00205 60d5a02655ea1f2926180e88860939e9 212 Pfam PF02223 Thymidylate kinase 8 198 1.3E-55 T 11-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 UP12_00205 60d5a02655ea1f2926180e88860939e9 212 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 11-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UP12_00205 60d5a02655ea1f2926180e88860939e9 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 1.7E-64 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UP12_00205 60d5a02655ea1f2926180e88860939e9 212 Gene3D G3DSA:3.40.50.300 1 211 7.8E-68 T 11-10-2018 UP12_00205 60d5a02655ea1f2926180e88860939e9 212 SUPERFAMILY SSF52540 1 209 1.44E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02350 fbf871a93d250bf3151a7cec4c70ca32 351 SMART SM01329 5 345 1.6E-162 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UP12_02350 fbf871a93d250bf3151a7cec4c70ca32 351 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 1 349 3.0E-183 T 11-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 UP12_02350 fbf871a93d250bf3151a7cec4c70ca32 351 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 345 1.7E-84 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 UP12_02350 fbf871a93d250bf3151a7cec4c70ca32 351 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 UP12_02350 fbf871a93d250bf3151a7cec4c70ca32 351 Gene3D G3DSA:3.40.718.10 1 351 7.8E-126 T 11-10-2018 UP12_02350 fbf871a93d250bf3151a7cec4c70ca32 351 SUPERFAMILY SSF53659 2 349 2.16E-112 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49401 631 749 7.95E-18 T 11-10-2018 IPR008966 Adhesion domain superfamily UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2010 2042 3.0E-5 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1055 1150 8.9E-20 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1895 2015 1.2E-23 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.740 622 765 4.5E-5 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Pfam PF05737 Collagen binding domain 765 896 5.3E-25 T 11-10-2018 IPR008456 Collagen binding domain GO:0005518 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Pfam PF05737 Collagen binding domain 493 600 2.3E-17 T 11-10-2018 IPR008456 Collagen binding domain GO:0005518 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Pfam PF05737 Collagen binding domain 632 725 4.0E-7 T 11-10-2018 IPR008456 Collagen binding domain GO:0005518 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Pfam PF05737 Collagen binding domain 350 472 1.2E-23 T 11-10-2018 IPR008456 Collagen binding domain GO:0005518 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Pfam PF05737 Collagen binding domain 915 1033 1.5E-13 T 11-10-2018 IPR008456 Collagen binding domain GO:0005518 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1902 1963 1.92E-7 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1257 1321 4.32E-8 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1719 1782 3.18E-8 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49401 764 904 9.19E-25 T 11-10-2018 IPR008966 Adhesion domain superfamily UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49401 489 615 7.45E-21 T 11-10-2018 IPR008966 Adhesion domain superfamily UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1062 1133 9.42E-10 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1151 1242 1.0E-26 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1520 1611 1.3E-20 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1796 1890 6.8E-27 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1334 1426 4.5E-22 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1707 1795 4.2E-24 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1427 1519 2.1E-26 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1612 1706 1.1E-26 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.10 1243 1333 1.8E-26 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Pfam PF00746 LPXTG cell wall anchor motif 2004 2042 1.3E-5 T 11-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1441 1503 2.71E-7 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1533 1597 1.06E-6 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.1280 216 347 1.1E-17 T 11-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1164 1227 1.29E-8 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1349 1410 5.49E-8 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49401 907 1041 1.47E-24 T 11-10-2018 IPR008966 Adhesion domain superfamily UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1809 1873 7.85E-7 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49401 210 343 3.35E-23 T 11-10-2018 IPR008966 Adhesion domain superfamily UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49478 1628 1692 1.53E-7 T 11-10-2018 UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 SUPERFAMILY SSF49401 349 486 1.47E-21 T 11-10-2018 IPR008966 Adhesion domain superfamily UP12_04150 84c1414e1ab2d5ee92723c9ab13b5880 2045 Gene3D G3DSA:2.60.40.1280 26 163 1.3E-5 T 11-10-2018 IPR011252 Fibrogen-binding domain 1 GO:0007155 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 Gene3D G3DSA:1.10.540.10 2 117 1.2E-28 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 222 369 2.4E-38 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 330 349 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 Gene3D G3DSA:1.20.140.10 228 377 8.5E-41 T 11-10-2018 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 SUPERFAMILY SSF56645 10 228 5.24E-64 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 Gene3D G3DSA:2.40.110.10 118 227 1.3E-31 T 11-10-2018 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 SUPERFAMILY SSF47203 220 375 4.67E-42 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 209 2.5E-22 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UP12_03525 73993fa492d7f438ededbe47a8ec2a70 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 115 1.1E-24 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Gene3D G3DSA:3.90.740.10 226 410 5.4E-278 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 409 603 2.2E-20 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 803 23.24 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 803 0.0 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Gene3D G3DSA:2.30.210.10 572 587 5.4E-278 T 11-10-2018 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Gene3D G3DSA:3.40.50.620 32 571 5.4E-278 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Gene3D G3DSA:3.10.20.590 744 803 6.1E-22 T 11-10-2018 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 SUPERFAMILY SSF47323 619 803 3.92E-39 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Gene3D G3DSA:1.10.730.10 599 740 9.6E-46 T 11-10-2018 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 3.8E-70 T 11-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Pfam PF09334 tRNA synthetases class I (M) 39 170 1.7E-17 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 Pfam PF08264 Anticodon-binding domain of tRNA 655 766 3.6E-20 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 SUPERFAMILY SSF50677 224 410 1.02E-55 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 SUPERFAMILY SSF52374 5 625 2.82E-144 T 11-10-2018 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 2.1E-57 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 2.1E-57 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 2.1E-57 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 2.1E-57 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 2.1E-57 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 2.1E-57 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_13655 8a144b0e81c2c840c0e6049a44694a2b 804 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 2.1E-57 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 UP12_11975 9edf483a1ff3a3833146f9e8988af46b 138 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 27.416 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UP12_11975 9edf483a1ff3a3833146f9e8988af46b 138 SMART SM00732 1 103 6.2E-37 T 11-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 UP12_11975 9edf483a1ff3a3833146f9e8988af46b 138 Pfam PF03652 Holliday junction resolvase 1 136 5.5E-44 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UP12_11975 9edf483a1ff3a3833146f9e8988af46b 138 SUPERFAMILY SSF53098 1 137 1.67E-44 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_11975 9edf483a1ff3a3833146f9e8988af46b 138 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 1.5E-56 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 UP12_11975 9edf483a1ff3a3833146f9e8988af46b 138 Gene3D G3DSA:3.30.420.140 1 138 7.4E-51 T 11-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 UP12_18940 26f8098bee355526527935820c195e9c 193 Pfam PF14278 Transcriptional regulator C-terminal region 96 172 1.2E-6 T 11-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type UP12_18940 26f8098bee355526527935820c195e9c 193 SUPERFAMILY SSF46689 9 72 1.45E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_18940 26f8098bee355526527935820c195e9c 193 Gene3D G3DSA:1.10.357.10 7 190 3.2E-38 T 11-10-2018 UP12_18940 26f8098bee355526527935820c195e9c 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 1.7E-4 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 SUPERFAMILY SSF51984 7 98 5.89E-16 T 11-10-2018 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 447 34.69 T 11-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 Pfam PF02875 Mur ligase family, glutamate ligase domain 309 363 1.6E-7 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 Gene3D G3DSA:3.40.1190.10 100 306 1.0E-62 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 Gene3D G3DSA:3.40.50.720 7 93 2.8E-27 T 11-10-2018 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 SUPERFAMILY SSF53244 308 447 8.7E-39 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 Gene3D G3DSA:3.90.190.20 313 446 1.9E-38 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 SUPERFAMILY SSF53623 101 306 1.51E-52 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 8 445 4.2E-142 T 11-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_07370 7fa073eefcb36f6f0d9757d95323df1a 448 Pfam PF08245 Mur ligase middle domain 115 289 2.6E-35 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 489 2.1E-6 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 2 499 1.2E-212 T 11-10-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 425 1.2E-100 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 Pfam PF00501 AMP-binding enzyme 11 401 1.5E-85 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 Gene3D G3DSA:3.30.300.30 396 500 7.0E-29 T 11-10-2018 UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 PRINTS PR00154 AMP-binding signature 141 152 7.1E-5 T 11-10-2018 IPR020459 AMP-binding UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 PRINTS PR00154 AMP-binding signature 153 161 7.1E-5 T 11-10-2018 IPR020459 AMP-binding UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 Gene3D G3DSA:3.40.50.12780 1 395 7.1E-127 T 11-10-2018 UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 Hamap MF_00593 D-alanine--D-alanyl carrier protein ligase [dltA]. 1 501 232.456 T 11-10-2018 IPR010072 D-alanine--D-alanyl carrier protein ligase GO:0005524|GO:0047473|GO:0070395 UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 SUPERFAMILY SSF56801 5 498 1.26E-119 T 11-10-2018 UP12_12465 e120f96575d2e568ab17f5c8335575e1 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 146 157 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_09615 951268209214c065afeccdb5620ef82d 461 Gene3D G3DSA:3.30.750.44 45 333 3.3E-98 T 11-10-2018 UP12_09615 951268209214c065afeccdb5620ef82d 461 SUPERFAMILY SSF52096 36 362 1.62E-67 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_09615 951268209214c065afeccdb5620ef82d 461 SUPERFAMILY SSF50156 96 181 2.59E-17 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_09615 951268209214c065afeccdb5620ef82d 461 Gene3D G3DSA:2.30.42.10 99 185 3.3E-98 T 11-10-2018 UP12_09615 951268209214c065afeccdb5620ef82d 461 Pfam PF03572 Peptidase family S41 196 356 7.5E-51 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UP12_09615 951268209214c065afeccdb5620ef82d 461 SUPERFAMILY SSF47090 367 436 1.02E-11 T 11-10-2018 IPR036365 PGBD-like superfamily UP12_09615 951268209214c065afeccdb5620ef82d 461 Gene3D G3DSA:1.10.101.10 367 446 2.7E-11 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UP12_09615 951268209214c065afeccdb5620ef82d 461 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 50 375 2.5E-124 T 11-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 UP12_09615 951268209214c065afeccdb5620ef82d 461 SMART SM00245 171 358 9.8E-76 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UP12_09615 951268209214c065afeccdb5620ef82d 461 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 99 166 2.2E-12 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_09615 951268209214c065afeccdb5620ef82d 461 SMART SM00228 99 170 2.0E-17 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_09615 951268209214c065afeccdb5620ef82d 461 Gene3D G3DSA:3.90.226.10 186 355 3.3E-98 T 11-10-2018 UP12_09615 951268209214c065afeccdb5620ef82d 461 Pfam PF01471 Putative peptidoglycan binding domain 380 434 2.0E-8 T 11-10-2018 IPR002477 Peptidoglycan binding-like UP12_19695 3678ce8be079b662b7c4557b18588120 94 Pfam PF17362 Family of unknown function 21 85 1.1E-10 T 11-10-2018 IPR020270 Uncharacterised protein family, plasmid pXO2-34 UP12_09985 3ee1d67a6d864abf61e59e980f6f7599 123 SUPERFAMILY SSF140415 2 122 6.15E-37 T 11-10-2018 IPR023351 YppE-like superfamily UP12_09985 3ee1d67a6d864abf61e59e980f6f7599 123 Gene3D G3DSA:1.20.120.440 2 123 3.7E-33 T 11-10-2018 IPR023351 YppE-like superfamily UP12_09985 3ee1d67a6d864abf61e59e980f6f7599 123 Pfam PF08807 Bacterial domain of unknown function (DUF1798) 10 119 1.4E-32 T 11-10-2018 IPR014913 Protein of unknown function DUF1798 UP12_16965 b82645e3293acb3944a18d4a803496ea 262 SUPERFAMILY SSF55785 19 129 1.19E-21 T 11-10-2018 IPR035965 PAS domain superfamily UP12_16965 b82645e3293acb3944a18d4a803496ea 262 Pfam PF01740 STAS domain 153 256 1.3E-5 T 11-10-2018 IPR002645 STAS domain UP12_16965 b82645e3293acb3944a18d4a803496ea 262 Pfam PF13426 PAS domain 33 130 2.2E-20 T 11-10-2018 IPR000014 PAS domain UP12_16965 b82645e3293acb3944a18d4a803496ea 262 SMART SM00086 87 131 0.0013 T 11-10-2018 IPR001610 PAC motif UP12_16965 b82645e3293acb3944a18d4a803496ea 262 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 137 2.1E-17 T 11-10-2018 IPR000014 PAS domain UP12_16965 b82645e3293acb3944a18d4a803496ea 262 Gene3D G3DSA:3.30.450.20 24 149 1.1E-44 T 11-10-2018 UP12_16965 b82645e3293acb3944a18d4a803496ea 262 SUPERFAMILY SSF52091 152 260 1.06E-12 T 11-10-2018 IPR036513 STAS domain superfamily UP12_16965 b82645e3293acb3944a18d4a803496ea 262 SMART SM00091 12 81 0.002 T 11-10-2018 IPR000014 PAS domain UP12_16965 b82645e3293acb3944a18d4a803496ea 262 Gene3D G3DSA:3.30.750.24 150 262 7.9E-28 T 11-10-2018 IPR036513 STAS domain superfamily UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 296 56.531 T 11-10-2018 IPR023009 Tyrosine recombinase XerC/XerD UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 7 296 6.5E-102 T 11-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 296 7.7E-122 T 11-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 SUPERFAMILY SSF56349 7 289 1.12E-60 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 Gene3D G3DSA:1.10.150.130 2 97 1.0E-22 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 Gene3D G3DSA:1.10.443.10 110 290 3.9E-70 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 296 63.401 T 11-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 89 2.5E-20 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UP12_10580 a5d5d72922ec75e6dadaae4488bf8b3c 296 Pfam PF00589 Phage integrase family 111 282 6.5E-56 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UP12_00760 f3527853780abeced6befc2565a4e57a 144 SUPERFAMILY SSF54686 1 137 1.7E-59 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00760 f3527853780abeced6befc2565a4e57a 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 11-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00760 f3527853780abeced6befc2565a4e57a 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.632 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00760 f3527853780abeced6befc2565a4e57a 144 Gene3D G3DSA:3.90.1170.10 1 143 6.8E-56 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00760 f3527853780abeced6befc2565a4e57a 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.6E-53 T 11-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 UP12_00760 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 8.4E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00760 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 8.4E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00760 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 8.4E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00760 f3527853780abeced6befc2565a4e57a 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 8.4E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00760 f3527853780abeced6befc2565a4e57a 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 5.8E-64 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00760 f3527853780abeced6befc2565a4e57a 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 11-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_03365 6d746471231420b8d37084d526d479e9 743 Pfam PF00586 AIR synthase related protein, N-terminal domain 89 194 1.3E-25 T 11-10-2018 IPR016188 PurM-like, N-terminal domain UP12_03365 6d746471231420b8d37084d526d479e9 743 Pfam PF00586 AIR synthase related protein, N-terminal domain 445 562 3.0E-25 T 11-10-2018 IPR016188 PurM-like, N-terminal domain UP12_03365 6d746471231420b8d37084d526d479e9 743 SUPERFAMILY SSF56042 204 430 5.23E-57 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 SUPERFAMILY SSF55326 403 569 1.83E-57 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 SUPERFAMILY SSF56042 572 739 4.19E-37 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 Gene3D G3DSA:3.30.1330.10 391 565 9.8E-63 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 Gene3D G3DSA:3.30.1330.10 49 197 5.7E-136 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 Gene3D G3DSA:3.90.650.10 569 741 5.4E-39 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 SUPERFAMILY SSF55326 18 201 7.92E-52 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 738 0.0 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03365 6d746471231420b8d37084d526d479e9 743 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 743 330.399 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03365 6d746471231420b8d37084d526d479e9 743 PIRSF PIRSF001587 8 742 0.0 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03365 6d746471231420b8d37084d526d479e9 743 Gene3D G3DSA:3.90.650.10 35 362 5.7E-136 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_03365 6d746471231420b8d37084d526d479e9 743 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 709 4.3E-16 T 11-10-2018 IPR010918 PurM-like, C-terminal domain UP12_03365 6d746471231420b8d37084d526d479e9 743 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 357 3.8E-32 T 11-10-2018 IPR010918 PurM-like, C-terminal domain UP12_00725 a1fbf25f0e8725067f8b1ea49cb489e4 209 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 203 5.3E-87 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00725 a1fbf25f0e8725067f8b1ea49cb489e4 209 ProSitePatterns PS00474 Ribosomal protein L3 signature. 102 125 - T 11-10-2018 IPR019926 Ribosomal protein L3, conserved site UP12_00725 a1fbf25f0e8725067f8b1ea49cb489e4 209 Gene3D G3DSA:2.40.50.620 33 96 7.4E-15 T 11-10-2018 UP12_00725 a1fbf25f0e8725067f8b1ea49cb489e4 209 SUPERFAMILY SSF50447 1 207 2.56E-80 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_00725 a1fbf25f0e8725067f8b1ea49cb489e4 209 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 206 39.024 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00725 a1fbf25f0e8725067f8b1ea49cb489e4 209 Pfam PF00297 Ribosomal protein L3 99 181 2.5E-16 T 11-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00725 a1fbf25f0e8725067f8b1ea49cb489e4 209 Gene3D G3DSA:2.40.30.10 130 209 2.6E-18 T 11-10-2018 UP12_05270 7f4f2ccd0c0d9f7319d7440e7bc22f47 322 Gene3D G3DSA:1.10.260.150 57 322 8.5E-77 T 11-10-2018 UP12_05270 7f4f2ccd0c0d9f7319d7440e7bc22f47 322 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 93 242 1.6E-35 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_05270 7f4f2ccd0c0d9f7319d7440e7bc22f47 322 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 94 242 2.5E-39 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 2 431 42.156 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 SUPERFAMILY SSF55681 111 425 9.33E-99 T 11-10-2018 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 Gene3D G3DSA:3.30.930.10 103 431 7.2E-120 T 11-10-2018 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 Gene3D G3DSA:2.40.50.140 2 102 4.4E-24 T 11-10-2018 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 2 430 1.0E-172 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 SUPERFAMILY SSF50249 10 103 9.64E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 386 400 7.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 346 362 7.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 7.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 7.4E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 Pfam PF01336 OB-fold nucleic acid binding domain 17 96 5.4E-17 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UP12_10030 720342bbf4de65995feb6b9d8cdbd9df 431 Pfam PF00152 tRNA synthetases class II (D, K and N) 112 425 1.5E-85 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 SUPERFAMILY SSF143800 1 80 7.06E-19 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 Pfam PF01197 Ribosomal protein L31 2 79 2.7E-22 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.8E-14 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.8E-14 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.8E-14 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 4.5E-14 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_13860 09c00e580026b8c9c0e7f0db3340996d 80 Gene3D G3DSA:2.30.170.50 1 80 2.9E-19 T 11-10-2018 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 SMART SM00870 58 376 8.4E-137 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 PRINTS PR00139 Asparaginase/glutaminase family signature 59 70 1.1E-21 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 PRINTS PR00139 Asparaginase/glutaminase family signature 139 157 1.1E-21 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 PRINTS PR00139 Asparaginase/glutaminase family signature 318 336 1.1E-21 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 Gene3D G3DSA:3.40.50.40 271 382 4.9E-38 T 11-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 61 69 - T 11-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 Gene3D G3DSA:3.40.50.1170 53 270 1.6E-85 T 11-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 PIRSF PIRSF001220 53 381 1.7E-88 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 Pfam PF00710 Asparaginase, N-terminal 58 252 1.1E-58 T 11-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 47 382 1.1E-142 T 11-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 140 150 - T 11-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 PIRSF PIRSF500176 55 382 2.5E-75 T 11-10-2018 UP12_02925 a5fd423ce9b2de179905bfacd8fa8321 382 SUPERFAMILY SSF53774 57 381 1.31E-99 T 11-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 UP12_05400 a71050443bad78036b8d861f922c0dca 613 SUPERFAMILY SSF52402 230 575 2.33E-74 T 11-10-2018 UP12_05400 a71050443bad78036b8d861f922c0dca 613 Pfam PF00733 Asparagine synthase 242 604 1.1E-95 T 11-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UP12_05400 a71050443bad78036b8d861f922c0dca 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 532 2.3E-172 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UP12_05400 a71050443bad78036b8d861f922c0dca 613 SUPERFAMILY SSF56235 1 226 1.37E-63 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_05400 a71050443bad78036b8d861f922c0dca 613 PIRSF PIRSF001589 1 611 4.6E-148 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UP12_05400 a71050443bad78036b8d861f922c0dca 613 Pfam PF13537 Glutamine amidotransferase domain 48 169 5.8E-46 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain UP12_05400 a71050443bad78036b8d861f922c0dca 613 Gene3D G3DSA:3.60.20.10 2 184 2.8E-62 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 Gene3D G3DSA:3.40.1390.10 2 86 5.0E-20 T 11-10-2018 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 SUPERFAMILY SSF53623 105 311 1.57E-53 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 392 7.6E-15 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 Pfam PF08245 Mur ligase middle domain 111 294 4.6E-50 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 SUPERFAMILY SSF53244 316 454 1.47E-36 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 Gene3D G3DSA:3.40.1190.10 87 311 3.5E-69 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 SUPERFAMILY SSF63418 1 101 9.68E-24 T 11-10-2018 IPR035911 MurE/MurF, N-terminal UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 Pfam PF01225 Mur ligase family, catalytic domain 26 100 1.6E-13 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 Gene3D G3DSA:3.90.190.20 314 454 7.1E-43 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 454 33.576 T 11-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02490 ea0ae854f62cee2a162976f81dfd31c8 454 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 454 2.0E-136 T 11-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 SUPERFAMILY SSF46785 257 331 3.36E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 334 172.213 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 SUPERFAMILY SSF52540 21 253 2.87E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 328 6.0E-151 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 Gene3D G3DSA:1.10.8.60 183 257 9.5E-30 T 11-10-2018 UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 3.1E-35 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 235 2.2E-118 T 11-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 SMART SM00382 52 183 5.7E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 331 1.0E-35 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 Gene3D G3DSA:1.10.10.10 258 334 2.3E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_12150 16412ccab2a0845eeb277f13d46c2486 334 Gene3D G3DSA:3.40.50.300 19 182 4.8E-41 T 11-10-2018 UP12_05670 8886567581201177cccbbf7e83d379de 316 SUPERFAMILY SSF161098 91 303 1.7E-19 T 11-10-2018 IPR035906 MetI-like superfamily UP12_05670 8886567581201177cccbbf7e83d379de 316 Gene3D G3DSA:1.10.3720.10 86 310 7.4E-24 T 11-10-2018 IPR035906 MetI-like superfamily UP12_05670 8886567581201177cccbbf7e83d379de 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 315 6.8E-43 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 SUPERFAMILY SSF63520 289 384 2.75E-21 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Gene3D G3DSA:3.40.50.2300 395 476 2.6E-9 T 11-10-2018 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Gene3D G3DSA:1.10.1790.10 286 384 1.1E-15 T 11-10-2018 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 SUPERFAMILY SSF63520 184 269 5.49E-8 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Pfam PF08279 HTH domain 1 52 8.4E-8 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 SUPERFAMILY SSF52794 397 473 1.99E-8 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Gene3D G3DSA:3.40.930.10 528 678 7.3E-54 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 579 595 - T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 SUPERFAMILY SSF55804 529 674 1.06E-34 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Pfam PF05043 Mga helix-turn-helix domain 81 150 6.1E-5 T 11-10-2018 IPR007737 Mga helix-turn-helix domain UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Pfam PF00874 PRD domain 186 268 6.3E-8 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Pfam PF00874 PRD domain 294 382 1.1E-19 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 533 674 5.4E-33 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Gene3D G3DSA:1.10.1790.10 181 275 6.7E-6 T 11-10-2018 UP12_09035 4043e2d198f45982b14427e5f8cebbcb 678 Gene3D G3DSA:1.10.10.10 1 55 9.6E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05735 cf8b1e5ae1bb68318bfa91fa9483760f 221 Gene3D G3DSA:3.30.70.1950 123 221 1.8E-31 T 11-10-2018 IPR038471 MecA, C-terminal domain superfamily UP12_05735 cf8b1e5ae1bb68318bfa91fa9483760f 221 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 216 1.0E-53 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA UP12_05735 cf8b1e5ae1bb68318bfa91fa9483760f 221 Hamap MF_01124 Adapter protein MecA [mecA]. 1 220 27.635 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA UP12_05735 cf8b1e5ae1bb68318bfa91fa9483760f 221 PIRSF PIRSF029008 1 221 9.4E-76 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA UP12_16050 af58f8ac4bd969381fb064ec06463a99 624 Pfam PF02719 Polysaccharide biosynthesis protein 280 561 2.0E-120 T 11-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain UP12_16050 af58f8ac4bd969381fb064ec06463a99 624 Gene3D G3DSA:3.90.25.30 443 542 1.6E-114 T 11-10-2018 UP12_16050 af58f8ac4bd969381fb064ec06463a99 624 SUPERFAMILY SSF51735 277 542 2.43E-55 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16050 af58f8ac4bd969381fb064ec06463a99 624 Gene3D G3DSA:3.40.50.720 278 556 1.6E-114 T 11-10-2018 UP12_16050 af58f8ac4bd969381fb064ec06463a99 624 Gene3D G3DSA:3.40.50.720 135 261 1.9E-33 T 11-10-2018 UP12_16050 af58f8ac4bd969381fb064ec06463a99 624 SUPERFAMILY SSF51735 138 267 4.72E-14 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16050 af58f8ac4bd969381fb064ec06463a99 624 Pfam PF13727 CoA-binding domain 60 235 4.8E-15 T 11-10-2018 UP12_09440 9f8f8080271a46611e3f58487ca472d2 441 PIRSF PIRSF006060 2 435 5.5E-68 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_09440 9f8f8080271a46611e3f58487ca472d2 441 Gene3D G3DSA:1.20.1740.10 6 437 4.6E-70 T 11-10-2018 UP12_09440 9f8f8080271a46611e3f58487ca472d2 441 Pfam PF00324 Amino acid permease 18 431 1.9E-39 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_07775 b748f2d37531aa1e8f1164cf0de9d914 110 SUPERFAMILY SSF88659 3 102 9.53E-33 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_07775 b748f2d37531aa1e8f1164cf0de9d914 110 Hamap MF_00245 UPF0122 protein . 3 103 21.803 T 11-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like UP12_07775 b748f2d37531aa1e8f1164cf0de9d914 110 Gene3D G3DSA:1.10.10.10 1 110 1.9E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_07775 b748f2d37531aa1e8f1164cf0de9d914 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 99 1.8E-41 T 11-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 1.1E-41 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 Gene3D G3DSA:2.30.30.30 1 100 8.8E-43 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 Pfam PF00467 KOW motif 5 36 8.6E-9 T 11-10-2018 IPR005824 KOW UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.027 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 1.4E-30 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 SMART SM00739 2 29 7.4E-6 T 11-10-2018 IPR005824 KOW UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 11-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00780 89102c5434baa3aa7ef6a955e2467278 103 SUPERFAMILY SSF50104 1 100 1.81E-39 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily UP12_08600 6dc700d80f10553117ff7d477ea33597 137 Pfam PF02082 Transcriptional regulator 3 81 1.7E-20 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_08600 6dc700d80f10553117ff7d477ea33597 137 Gene3D G3DSA:1.10.10.10 1 137 2.1E-45 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08600 6dc700d80f10553117ff7d477ea33597 137 SUPERFAMILY SSF46785 3 135 1.47E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 SUPERFAMILY SSF53901 4 267 2.33E-79 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 83 101 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 3.9E-44 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 Gene3D G3DSA:3.40.47.10 125 388 2.2E-143 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 SUPERFAMILY SSF53901 269 389 8.26E-37 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 Pfam PF00108 Thiolase, N-terminal domain 5 259 1.7E-92 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 Gene3D G3DSA:3.40.47.10 5 274 2.2E-143 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 PIRSF PIRSF000429 1 390 2.8E-123 T 11-10-2018 IPR002155 Thiolase GO:0016747 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 388 1.3E-138 T 11-10-2018 IPR002155 Thiolase GO:0016747 UP12_17395 c7052279bd23f7260dd9eeb53ace198f 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 UP12_10445 23ca351ac693f6d93247485955add308 197 Pfam PF04079 Segregation and condensation complex subunit ScpB 10 169 2.6E-54 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UP12_10445 23ca351ac693f6d93247485955add308 197 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 195 4.8E-70 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UP12_10445 23ca351ac693f6d93247485955add308 197 Gene3D G3DSA:1.10.10.10 3 85 2.2E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10445 23ca351ac693f6d93247485955add308 197 PIRSF PIRSF019345 2 195 2.5E-54 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UP12_10445 23ca351ac693f6d93247485955add308 197 SUPERFAMILY SSF46785 87 160 4.54E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_10445 23ca351ac693f6d93247485955add308 197 Hamap MF_01804 Segregation and condensation protein B [scpB]. 6 185 34.553 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 UP12_10445 23ca351ac693f6d93247485955add308 197 SUPERFAMILY SSF46785 3 83 3.63E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_10445 23ca351ac693f6d93247485955add308 197 Gene3D G3DSA:1.10.10.10 86 181 3.3E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15950 225ba7779c635ecb37d331960280fd45 461 Gene3D G3DSA:3.30.450.20 7 114 3.8E-10 T 11-10-2018 UP12_15950 225ba7779c635ecb37d331960280fd45 461 Pfam PF00158 Sigma-54 interaction domain 129 294 2.9E-62 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 UP12_15950 225ba7779c635ecb37d331960280fd45 461 Gene3D G3DSA:1.10.8.60 300 379 1.2E-21 T 11-10-2018 UP12_15950 225ba7779c635ecb37d331960280fd45 461 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 214 229 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 UP12_15950 225ba7779c635ecb37d331960280fd45 461 SUPERFAMILY SSF46689 341 458 2.15E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_15950 225ba7779c635ecb37d331960280fd45 461 SUPERFAMILY SSF52540 128 370 7.99E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15950 225ba7779c635ecb37d331960280fd45 461 Gene3D G3DSA:1.10.10.60 400 461 8.3E-16 T 11-10-2018 UP12_15950 225ba7779c635ecb37d331960280fd45 461 SMART SM00382 149 292 5.4E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15950 225ba7779c635ecb37d331960280fd45 461 SUPERFAMILY SSF55785 1 101 4.54E-10 T 11-10-2018 IPR035965 PAS domain superfamily UP12_15950 225ba7779c635ecb37d331960280fd45 461 Gene3D G3DSA:3.40.50.300 115 299 4.9E-60 T 11-10-2018 UP12_15950 225ba7779c635ecb37d331960280fd45 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 341 350 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site UP12_15950 225ba7779c635ecb37d331960280fd45 461 Pfam PF08448 PAS fold 2 109 8.6E-7 T 11-10-2018 IPR013656 PAS fold-4 UP12_15950 225ba7779c635ecb37d331960280fd45 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 439 459 6.6E-7 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_15950 225ba7779c635ecb37d331960280fd45 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 439 6.6E-7 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_15950 225ba7779c635ecb37d331960280fd45 461 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 110 2.0E-6 T 11-10-2018 IPR000014 PAS domain UP12_15950 225ba7779c635ecb37d331960280fd45 461 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 153 166 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 UP12_15950 225ba7779c635ecb37d331960280fd45 461 Pfam PF02954 Bacterial regulatory protein, Fis family 416 456 5.5E-13 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_10850 cf5c56b79dba1f0c597b4adfec5b04eb 240 Gene3D G3DSA:3.40.50.300 1 240 3.1E-81 T 11-10-2018 UP12_10850 cf5c56b79dba1f0c597b4adfec5b04eb 240 PIRSF PIRSF039085 1 240 8.6E-113 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UP12_10850 cf5c56b79dba1f0c597b4adfec5b04eb 240 Pfam PF00005 ABC transporter 17 165 1.7E-38 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_10850 cf5c56b79dba1f0c597b4adfec5b04eb 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_10850 cf5c56b79dba1f0c597b4adfec5b04eb 240 SMART SM00382 26 213 7.4E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_10850 cf5c56b79dba1f0c597b4adfec5b04eb 240 SUPERFAMILY SSF52540 1 235 4.63E-80 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10645 4e5bb47299e93959169fcb94560eb0da 310 Gene3D G3DSA:3.40.50.1820 53 309 5.4E-42 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_10645 4e5bb47299e93959169fcb94560eb0da 310 SUPERFAMILY SSF53474 50 306 1.52E-44 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_10645 4e5bb47299e93959169fcb94560eb0da 310 Pfam PF00326 Prolyl oligopeptidase family 130 302 2.2E-11 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UP12_02570 d056092d960277c95cda1aae0471ddda 109 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 1.9E-29 T 11-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UP12_02570 d056092d960277c95cda1aae0471ddda 109 Pfam PF13466 STAS domain 16 94 9.6E-16 T 11-10-2018 IPR002645 STAS domain UP12_02570 d056092d960277c95cda1aae0471ddda 109 Gene3D G3DSA:3.30.750.24 2 109 1.2E-25 T 11-10-2018 IPR036513 STAS domain superfamily UP12_02570 d056092d960277c95cda1aae0471ddda 109 SUPERFAMILY SSF52091 3 105 3.73E-25 T 11-10-2018 IPR036513 STAS domain superfamily UP12_06030 a75225cf0a20b50e9b14bdd480d49981 232 SUPERFAMILY SSF53681 119 224 2.62E-24 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_06030 a75225cf0a20b50e9b14bdd480d49981 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 2 229 1.4E-69 T 11-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 UP12_06030 a75225cf0a20b50e9b14bdd480d49981 232 Gene3D G3DSA:3.40.50.1860 4 218 7.5E-81 T 11-10-2018 UP12_06030 a75225cf0a20b50e9b14bdd480d49981 232 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 190 200 - T 11-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_06030 a75225cf0a20b50e9b14bdd480d49981 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 220 2.8E-63 T 11-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_06030 a75225cf0a20b50e9b14bdd480d49981 232 SUPERFAMILY SSF53681 4 114 7.19E-33 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_06030 a75225cf0a20b50e9b14bdd480d49981 232 Gene3D G3DSA:3.40.50.1860 106 212 7.5E-81 T 11-10-2018 UP12_17270 c0ade4a3ef09338446d977915555e0b4 294 Gene3D G3DSA:1.10.8.10 7 88 1.1E-18 T 11-10-2018 UP12_17270 c0ade4a3ef09338446d977915555e0b4 294 SUPERFAMILY SSF53335 7 285 8.06E-50 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_17270 c0ade4a3ef09338446d977915555e0b4 294 Pfam PF05175 Methyltransferase small domain 110 203 2.6E-16 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 UP12_17270 c0ade4a3ef09338446d977915555e0b4 294 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 29 284 6.9E-83 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 UP12_17270 c0ade4a3ef09338446d977915555e0b4 294 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 7 289 7.5E-82 T 11-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 UP12_17270 c0ade4a3ef09338446d977915555e0b4 294 Gene3D G3DSA:3.40.50.150 89 292 8.5E-61 T 11-10-2018 UP12_17270 c0ade4a3ef09338446d977915555e0b4 294 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 8 288 40.63 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 Gene3D G3DSA:3.40.50.300 286 547 1.6E-61 T 11-10-2018 UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 SUPERFAMILY SSF52540 312 524 1.21E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 Gene3D G3DSA:1.10.287.380 548 623 4.1E-11 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 Pfam PF00005 ABC transporter 342 469 4.3E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 Pfam PF16326 ABC transporter C-terminal domain 554 619 6.1E-17 T 11-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 Pfam PF12848 ABC transporter 226 300 8.2E-12 T 11-10-2018 IPR032781 ABC-transporter extension domain UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 SUPERFAMILY SSF52540 3 247 2.59E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 Pfam PF00005 ABC transporter 20 187 4.2E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 SMART SM00382 343 510 3.6E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 SMART SM00382 28 231 1.2E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_03790 0dcd8f93053624bc6e2120cb28e31d42 627 Gene3D G3DSA:3.40.50.300 2 281 4.9E-70 T 11-10-2018 UP12_02070 d7c9ab2b4aa1dd003e4f2416e708b053 247 SUPERFAMILY SSF52540 1 239 5.77E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02070 d7c9ab2b4aa1dd003e4f2416e708b053 247 Gene3D G3DSA:3.40.50.300 1 245 4.2E-77 T 11-10-2018 UP12_02070 d7c9ab2b4aa1dd003e4f2416e708b053 247 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_02070 d7c9ab2b4aa1dd003e4f2416e708b053 247 SMART SM00382 26 223 1.8E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_02070 d7c9ab2b4aa1dd003e4f2416e708b053 247 PIRSF PIRSF039085 1 245 9.4E-112 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UP12_02070 d7c9ab2b4aa1dd003e4f2416e708b053 247 Pfam PF00005 ABC transporter 17 169 1.5E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 Pfam PF01297 Zinc-uptake complex component A periplasmic 38 308 8.6E-78 T 11-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 SUPERFAMILY SSF53807 17 311 2.4E-86 T 11-10-2018 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 60 78 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 268 286 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 289 307 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 223 241 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 35 56 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 79 98 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 139 158 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 246 263 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00691 Adhesin B signature 197 214 7.1E-80 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 Gene3D G3DSA:3.40.50.1980 22 181 4.4E-52 T 11-10-2018 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 Gene3D G3DSA:3.40.50.1980 182 312 1.0E-44 T 11-10-2018 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00690 Adhesin family signature 276 295 1.2E-48 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00690 Adhesin family signature 250 268 1.2E-48 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00690 Adhesin family signature 35 53 1.2E-48 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00690 Adhesin family signature 66 79 1.2E-48 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00690 Adhesin family signature 197 218 1.2E-48 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_15730 05bc99080fa4e818758d2abc1019c4f9 312 PRINTS PR00690 Adhesin family signature 79 96 1.2E-48 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_13150 6c403e0d372eca3d44566680a2911d3a 313 Gene3D G3DSA:3.10.310.30 199 313 9.9E-36 T 11-10-2018 UP12_13150 6c403e0d372eca3d44566680a2911d3a 313 Pfam PF01368 DHH family 15 153 1.8E-13 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_13150 6c403e0d372eca3d44566680a2911d3a 313 Pfam PF02272 DHHA1 domain 179 308 6.1E-16 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 UP12_13150 6c403e0d372eca3d44566680a2911d3a 313 Gene3D G3DSA:3.90.1640.10 1 197 9.9E-60 T 11-10-2018 UP12_13150 6c403e0d372eca3d44566680a2911d3a 313 SUPERFAMILY SSF64182 13 281 3.4E-73 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily UP12_01775 d794b53ce15739255f3a62220602b7d3 273 Pfam PF02540 NAD synthase 23 264 4.2E-77 T 11-10-2018 IPR022310 NAD/GMP synthase UP12_01775 d794b53ce15739255f3a62220602b7d3 273 SUPERFAMILY SSF52402 3 272 2.46E-82 T 11-10-2018 UP12_01775 d794b53ce15739255f3a62220602b7d3 273 Gene3D G3DSA:3.40.50.620 1 273 2.1E-83 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_01775 d794b53ce15739255f3a62220602b7d3 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 18 267 49.382 T 11-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 UP12_01775 d794b53ce15739255f3a62220602b7d3 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 273 5.7E-82 T 11-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 Gene3D G3DSA:3.40.640.10 66 333 1.1E-158 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 SUPERFAMILY SSF53383 31 436 7.98E-130 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 Gene3D G3DSA:3.90.1150.10 16 431 1.1E-158 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 Pfam PF00202 Aminotransferase class-III 32 434 5.0E-125 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 PIRSF PIRSF000521 33 138 5.1E-7 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 PIRSF PIRSF000521 130 438 3.8E-37 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_02170 cec17cbadeb2694d1d475334a8ff0fae 438 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 17 436 3.4E-214 T 11-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 UP12_11360 022338769eb328bb801ac8550153e8f1 192 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 4 181 7.3E-14 T 11-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 UP12_11360 022338769eb328bb801ac8550153e8f1 192 SUPERFAMILY SSF56784 4 162 3.83E-18 T 11-10-2018 IPR036412 HAD-like superfamily UP12_11360 022338769eb328bb801ac8550153e8f1 192 PIRSF PIRSF021362 1 191 2.5E-79 T 11-10-2018 IPR009206 Nucleotidase, putative UP12_11360 022338769eb328bb801ac8550153e8f1 192 Gene3D G3DSA:3.40.50.1000 1 166 1.5E-14 T 11-10-2018 IPR023214 HAD superfamily UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 Gene3D G3DSA:2.40.33.10 71 167 3.9E-150 T 11-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 11-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 SUPERFAMILY SSF50800 70 167 9.59E-26 T 11-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 SUPERFAMILY SSF51621 1 342 1.19E-105 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 SUPERFAMILY SSF52009 466 583 4.58E-29 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 Gene3D G3DSA:3.20.20.60 4 332 3.9E-150 T 11-10-2018 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 2.2E-190 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 1.9E-36 T 11-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 SUPERFAMILY SSF52935 323 474 2.49E-42 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 Pfam PF00224 Pyruvate kinase, barrel domain 1 343 9.2E-158 T 11-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 Gene3D G3DSA:3.50.30.10 475 586 9.8E-35 T 11-10-2018 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.7E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.7E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.7E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.7E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.7E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.7E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.7E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 507 576 1.2E-21 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 UP12_13105 48e10d8a9602b4cd6a1a447f8cb9f184 586 Gene3D G3DSA:3.40.1380.20 340 473 4.9E-46 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 1.1E-20 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 4.2E-18 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SUPERFAMILY SSF54791 556 641 1.97E-23 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Pfam PF00575 S1 RNA binding domain 620 691 3.6E-18 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 4.0E-17 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Pfam PF03725 3' exoribonuclease family, domain 2 460 530 5.3E-7 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 PIRSF PIRSF005499 2 705 1.1E-302 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SUPERFAMILY SSF50249 621 704 1.42E-20 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SUPERFAMILY SSF54211 7 144 5.57E-49 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Gene3D G3DSA:3.30.230.70 235 550 9.5E-120 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 693 0.0 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Gene3D G3DSA:3.30.1370.10 551 622 3.8E-21 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 30.945 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SMART SM00316 621 691 3.7E-24 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SUPERFAMILY SSF54211 292 488 5.57E-49 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Gene3D G3DSA:3.30.230.70 1 230 1.9E-85 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SMART SM00322 553 618 2.9E-13 T 11-10-2018 IPR004087 K Homology domain GO:0003676 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SUPERFAMILY SSF55666 145 235 2.49E-30 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 320 1.0E-16 T 11-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Gene3D G3DSA:2.40.50.140 623 694 1.5E-24 T 11-10-2018 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 SUPERFAMILY SSF55666 451 548 3.01E-27 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_08160 1bdbf7f9c20b059165110932538c9642 705 Pfam PF00013 KH domain 557 614 6.4E-10 T 11-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 Gene3D G3DSA:3.30.470.130 1 448 2.4E-186 T 11-10-2018 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 SUPERFAMILY SSF52440 1 113 2.3E-48 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 440 1.2E-33 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 4.9E-72 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.3E-46 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 SMART SM00878 336 441 3.7E-49 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 SUPERFAMILY SSF51246 332 442 8.89E-37 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UP12_09145 30c3457c5506b21f2bca9a10f843ca82 449 SUPERFAMILY SSF56059 83 350 2.83E-65 T 11-10-2018 UP12_05245 260218c469b5b14b6f36b5a39f9b13ef 368 Gene3D G3DSA:3.20.20.10 15 238 3.8E-107 T 11-10-2018 IPR029066 PLP-binding barrel UP12_05245 260218c469b5b14b6f36b5a39f9b13ef 368 SMART SM01119 254 351 2.6E-32 T 11-10-2018 IPR026956 D-serine dehydratase-like domain UP12_05245 260218c469b5b14b6f36b5a39f9b13ef 368 Gene3D G3DSA:2.40.37.20 6 362 3.8E-107 T 11-10-2018 UP12_05245 260218c469b5b14b6f36b5a39f9b13ef 368 SUPERFAMILY SSF51419 13 244 8.43E-39 T 11-10-2018 IPR029066 PLP-binding barrel UP12_05245 260218c469b5b14b6f36b5a39f9b13ef 368 Pfam PF01168 Alanine racemase, N-terminal domain 13 240 2.5E-29 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_05245 260218c469b5b14b6f36b5a39f9b13ef 368 Pfam PF14031 Putative serine dehydratase domain 254 349 8.1E-20 T 11-10-2018 IPR026956 D-serine dehydratase-like domain UP12_07000 cb54d1995212eeab374dd22040d32089 335 SUPERFAMILY SSF53067 6 141 3.76E-37 T 11-10-2018 UP12_07000 cb54d1995212eeab374dd22040d32089 335 Gene3D G3DSA:3.30.420.40 7 322 6.6E-123 T 11-10-2018 UP12_07000 cb54d1995212eeab374dd22040d32089 335 SUPERFAMILY SSF53067 144 328 2.27E-47 T 11-10-2018 UP12_07000 cb54d1995212eeab374dd22040d32089 335 Gene3D G3DSA:3.90.640.10 181 254 6.6E-123 T 11-10-2018 UP12_07000 cb54d1995212eeab374dd22040d32089 335 Pfam PF06723 MreB/Mbl protein 5 331 4.7E-143 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_07000 cb54d1995212eeab374dd22040d32089 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 182 202 9.6E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_07000 cb54d1995212eeab374dd22040d32089 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 9.6E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_07000 cb54d1995212eeab374dd22040d32089 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 127 146 9.6E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_07000 cb54d1995212eeab374dd22040d32089 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 9.6E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_07000 cb54d1995212eeab374dd22040d32089 335 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 9.6E-55 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_07000 cb54d1995212eeab374dd22040d32089 335 Gene3D G3DSA:3.30.420.40 149 312 6.6E-123 T 11-10-2018 UP12_07000 cb54d1995212eeab374dd22040d32089 335 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 331 6.6E-136 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_15040 a336f6a31ab62845a7d0164682456b91 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_15040 a336f6a31ab62845a7d0164682456b91 247 Gene3D G3DSA:3.40.50.720 2 236 2.6E-44 T 11-10-2018 UP12_15040 a336f6a31ab62845a7d0164682456b91 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 4.3E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15040 a336f6a31ab62845a7d0164682456b91 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.3E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15040 a336f6a31ab62845a7d0164682456b91 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 4.3E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15040 a336f6a31ab62845a7d0164682456b91 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.3E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15040 a336f6a31ab62845a7d0164682456b91 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.3E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15040 a336f6a31ab62845a7d0164682456b91 247 Pfam PF00106 short chain dehydrogenase 4 193 1.8E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15040 a336f6a31ab62845a7d0164682456b91 247 SUPERFAMILY SSF51735 4 230 6.15E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 506 5.5E-183 T 11-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 20 44 7.2E-12 T 11-10-2018 UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 7.2E-12 T 11-10-2018 UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 305 329 7.2E-12 T 11-10-2018 UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 7.2E-12 T 11-10-2018 UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 Gene3D G3DSA:1.20.1720.10 17 227 7.3E-44 T 11-10-2018 UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 Pfam PF07690 Major Facilitator Superfamily 22 412 6.3E-58 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_04680 cfd1f835d9cb14b210a11b4b3880bab6 539 SUPERFAMILY SSF103473 15 519 7.59E-75 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 Gene3D G3DSA:1.20.1260.30 1 184 1.3E-48 T 11-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 SUPERFAMILY SSF53335 6 520 2.13E-132 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 Pfam PF02384 N-6 DNA Methylase 167 486 6.2E-112 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 Gene3D G3DSA:3.40.50.150 188 480 1.2E-86 T 11-10-2018 UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 301 313 5.8E-21 T 11-10-2018 UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 190 206 5.8E-21 T 11-10-2018 UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 337 361 5.8E-21 T 11-10-2018 UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 219 233 5.8E-21 T 11-10-2018 UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 6 500 1.1E-125 T 11-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 Pfam PF12161 HsdM N-terminal domain 7 153 8.7E-25 T 11-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain UP12_15350 b2ee8690b062f004f815a6b695e1bea6 538 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 304 310 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 Gene3D G3DSA:3.30.300.10 394 513 3.2E-52 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 513 1.3E-159 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 Pfam PF00958 GMP synthase C terminal domain 421 512 6.1E-45 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 513 55.535 T 11-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 195 1.5E-85 T 11-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 SUPERFAMILY SSF52317 7 228 1.02E-60 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00097 Anthranilate synthase component II signature 80 91 4.3E-6 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00097 Anthranilate synthase component II signature 168 181 4.3E-6 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00097 Anthranilate synthase component II signature 53 62 4.3E-6 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 Gene3D G3DSA:3.40.50.880 2 196 2.0E-58 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 2.7E-6 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 2.7E-6 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 2.7E-6 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 4.9E-8 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 4.9E-8 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 4.9E-8 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 Pfam PF02540 NAD synthase 214 284 8.3E-6 T 11-10-2018 IPR022310 NAD/GMP synthase UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 Pfam PF00117 Glutamine amidotransferase class-I 11 190 9.6E-43 T 11-10-2018 IPR017926 Glutamine amidotransferase UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 Gene3D G3DSA:3.40.50.620 200 393 6.0E-76 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 SUPERFAMILY SSF52402 188 406 7.72E-61 T 11-10-2018 UP12_03270 f3b44ed6e47d0a617b41d753f9f6078d 513 SUPERFAMILY SSF54810 393 513 1.31E-51 T 11-10-2018 UP12_14725 1771de1243109d69214459b25bd8d597 658 Gene3D G3DSA:1.20.1480.50 269 360 1.7E-19 T 11-10-2018 UP12_14725 1771de1243109d69214459b25bd8d597 658 SUPERFAMILY SSF58104 321 657 2.49E-73 T 11-10-2018 UP12_14725 1771de1243109d69214459b25bd8d597 658 SUPERFAMILY SSF103190 87 190 9.42E-10 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_14725 1771de1243109d69214459b25bd8d597 658 Pfam PF00672 HAMP domain 302 349 3.9E-12 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14725 1771de1243109d69214459b25bd8d597 658 Gene3D G3DSA:3.30.450.20 59 263 1.9E-23 T 11-10-2018 UP12_14725 1771de1243109d69214459b25bd8d597 658 Pfam PF02743 Cache domain 60 263 7.2E-22 T 11-10-2018 IPR033479 Double Cache domain 1 UP12_14725 1771de1243109d69214459b25bd8d597 658 Gene3D G3DSA:1.10.287.950 378 657 1.0E-68 T 11-10-2018 UP12_14725 1771de1243109d69214459b25bd8d597 658 Gene3D G3DSA:3.30.450.20 71 181 1.9E-23 T 11-10-2018 UP12_14725 1771de1243109d69214459b25bd8d597 658 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 480 507 9.7E-23 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_14725 1771de1243109d69214459b25bd8d597 658 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 509 538 9.7E-23 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_14725 1771de1243109d69214459b25bd8d597 658 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 9.7E-23 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_14725 1771de1243109d69214459b25bd8d597 658 SMART SM00304 301 353 8.1E-15 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14725 1771de1243109d69214459b25bd8d597 658 SMART SM00283 382 657 2.2E-87 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_14725 1771de1243109d69214459b25bd8d597 658 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 428 610 3.9E-51 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_16580 289e461c5bb12750799669440429e577 224 SUPERFAMILY SSF53271 67 222 4.85E-22 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_16580 289e461c5bb12750799669440429e577 224 Gene3D G3DSA:3.40.50.2020 93 224 4.5E-17 T 11-10-2018 UP12_16580 289e461c5bb12750799669440429e577 224 Pfam PF00156 Phosphoribosyl transferase domain 157 222 7.8E-8 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UP12_18950 22c24b73352fdf0b4f305cf3734a0acf 137 SUPERFAMILY SSF54593 12 130 1.03E-20 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_18950 22c24b73352fdf0b4f305cf3734a0acf 137 Gene3D G3DSA:3.10.180.10 1 136 4.6E-52 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_18950 22c24b73352fdf0b4f305cf3734a0acf 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 126 8.6E-8 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_04210 801b916c84691e3774cb0576a445f0df 571 Gene3D G3DSA:1.20.1560.10 1 315 2.3E-87 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04210 801b916c84691e3774cb0576a445f0df 571 Pfam PF00005 ABC transporter 349 498 5.8E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04210 801b916c84691e3774cb0576a445f0df 571 SMART SM00382 358 544 7.1E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04210 801b916c84691e3774cb0576a445f0df 571 Gene3D G3DSA:3.40.50.300 319 570 1.8E-92 T 11-10-2018 UP12_04210 801b916c84691e3774cb0576a445f0df 571 Pfam PF00664 ABC transporter transmembrane region 17 286 4.0E-56 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_04210 801b916c84691e3774cb0576a445f0df 571 SUPERFAMILY SSF52540 321 569 1.55E-93 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04210 801b916c84691e3774cb0576a445f0df 571 SUPERFAMILY SSF90123 3 319 9.42E-84 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04210 801b916c84691e3774cb0576a445f0df 571 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_09435 74ac1338eb0695d1504c06a04e571366 109 SUPERFAMILY SSF46785 14 107 3.38E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09435 74ac1338eb0695d1504c06a04e571366 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 4.6E-14 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_09435 74ac1338eb0695d1504c06a04e571366 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 58 4.6E-14 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_09435 74ac1338eb0695d1504c06a04e571366 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 4.6E-14 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_09435 74ac1338eb0695d1504c06a04e571366 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 28 43 4.6E-14 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_09435 74ac1338eb0695d1504c06a04e571366 109 Gene3D G3DSA:1.10.10.10 4 109 5.9E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09435 74ac1338eb0695d1504c06a04e571366 109 SMART SM00418 26 104 4.6E-33 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_09435 74ac1338eb0695d1504c06a04e571366 109 Pfam PF01022 Bacterial regulatory protein, arsR family 33 79 3.9E-17 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_14170 e6e7074252bba2940dfa2e10b0603b4a 307 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 6 148 6.3E-31 T 11-10-2018 IPR018755 Bacteriophage Mu-like, Gp48 UP12_16525 5c3b7a97ca858de4684549042d596a50 134 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 121 2.7E-47 T 11-10-2018 IPR003713 Flagellar protein FliS GO:0044780 UP12_16525 5c3b7a97ca858de4684549042d596a50 134 Pfam PF02561 Flagellar protein FliS 7 118 4.6E-39 T 11-10-2018 IPR003713 Flagellar protein FliS GO:0044780 UP12_16525 5c3b7a97ca858de4684549042d596a50 134 SUPERFAMILY SSF101116 4 122 5.36E-38 T 11-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 UP12_16525 5c3b7a97ca858de4684549042d596a50 134 PIRSF PIRSF039090 1 129 1.4E-35 T 11-10-2018 IPR003713 Flagellar protein FliS GO:0044780 UP12_16525 5c3b7a97ca858de4684549042d596a50 134 Gene3D G3DSA:1.20.120.340 1 122 1.4E-39 T 11-10-2018 UP12_16000 278935d45f09549b22180f53dd39681c 392 Gene3D G3DSA:3.40.640.10 1 251 4.6E-85 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_16000 278935d45f09549b22180f53dd39681c 392 Gene3D G3DSA:3.90.1150.10 253 389 8.8E-43 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_16000 278935d45f09549b22180f53dd39681c 392 PIRSF PIRSF000390 2 383 1.6E-107 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UP12_16000 278935d45f09549b22180f53dd39681c 392 SUPERFAMILY SSF53383 6 380 9.3E-103 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_16000 278935d45f09549b22180f53dd39681c 392 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 19 375 9.4E-100 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 SMART SM00862 177 252 3.2E-17 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 Gene3D G3DSA:1.10.10.10 161 258 2.9E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 Pfam PF00072 Response regulator receiver domain 33 141 1.3E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 Pfam PF00486 Transcriptional regulatory protein, C terminal 179 251 4.9E-22 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 SUPERFAMILY SSF52172 31 153 1.21E-34 T 11-10-2018 IPR011006 CheY-like superfamily UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 SMART SM00448 31 141 2.1E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 Gene3D G3DSA:3.40.50.2300 31 155 1.4E-29 T 11-10-2018 UP12_13260 c05c6db8402482c3c8a3f2e3b8f02ec6 258 SUPERFAMILY SSF46894 160 251 1.79E-23 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_17590 58fce006924e3371575d2dec0b5979a7 386 Gene3D G3DSA:1.20.1250.20 5 198 4.1E-28 T 11-10-2018 UP12_17590 58fce006924e3371575d2dec0b5979a7 386 Gene3D G3DSA:1.20.1250.20 199 385 1.1E-16 T 11-10-2018 UP12_17590 58fce006924e3371575d2dec0b5979a7 386 Pfam PF07690 Major Facilitator Superfamily 12 327 2.0E-42 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_17590 58fce006924e3371575d2dec0b5979a7 386 SUPERFAMILY SSF103473 4 383 2.49E-59 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 Pfam PF00271 Helicase conserved C-terminal domain 228 336 2.3E-29 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 SUPERFAMILY SSF52540 71 358 3.08E-76 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 11-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 Pfam PF00270 DEAD/DEAH box helicase 27 192 3.8E-50 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 SMART SM00487 22 219 3.2E-66 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 3 495 45.891 T 11-10-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 Gene3D G3DSA:3.40.50.300 210 437 3.3E-54 T 11-10-2018 UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 Gene3D G3DSA:3.40.50.300 2 208 2.3E-77 T 11-10-2018 UP12_02505 10e3ee67aefbb32b4df610daba13a535 497 SMART SM00490 255 336 1.7E-35 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_06705 33cbce761d011252451be6e20fb20d0b 88 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 11-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site UP12_06705 33cbce761d011252451be6e20fb20d0b 88 SUPERFAMILY SSF55594 1 83 1.44E-28 T 11-10-2018 IPR035895 HPr-like superfamily UP12_06705 33cbce761d011252451be6e20fb20d0b 88 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.9E-26 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_06705 33cbce761d011252451be6e20fb20d0b 88 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.9E-26 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_06705 33cbce761d011252451be6e20fb20d0b 88 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.9E-26 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_06705 33cbce761d011252451be6e20fb20d0b 88 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 11-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site UP12_06705 33cbce761d011252451be6e20fb20d0b 88 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.1E-29 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_06705 33cbce761d011252451be6e20fb20d0b 88 Gene3D G3DSA:3.30.1340.10 1 88 4.3E-37 T 11-10-2018 IPR035895 HPr-like superfamily UP12_06705 33cbce761d011252451be6e20fb20d0b 88 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 5.9E-33 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_11500 e2311c396cc59fc0a133776a429ac979 396 PIRSF PIRSF029895 1 396 4.0E-176 T 11-10-2018 IPR010690 Putative stage IV sporulation YqfD UP12_11500 e2311c396cc59fc0a133776a429ac979 396 Pfam PF06898 Putative stage IV sporulation protein YqfD 8 386 8.3E-117 T 11-10-2018 IPR010690 Putative stage IV sporulation YqfD UP12_11500 e2311c396cc59fc0a133776a429ac979 396 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 388 5.6E-113 T 11-10-2018 IPR010690 Putative stage IV sporulation YqfD UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 Pfam PF07238 PilZ domain 681 751 2.5E-7 T 11-10-2018 IPR009875 PilZ domain GO:0035438 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 Pfam PF07238 PilZ domain 527 624 4.1E-8 T 11-10-2018 IPR009875 PilZ domain GO:0035438 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 Gene3D G3DSA:3.90.550.10 98 315 3.4E-81 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 SUPERFAMILY SSF141371 543 625 3.92E-7 T 11-10-2018 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 SUPERFAMILY SSF141371 659 752 1.16E-5 T 11-10-2018 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 SUPERFAMILY SSF53448 100 382 1.13E-45 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 Pfam PF03552 Cellulose synthase 280 404 3.7E-6 T 11-10-2018 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 PRINTS PR01439 Cellulose synthase subunit A signature 115 134 1.7E-14 T 11-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 PRINTS PR01439 Cellulose synthase subunit A signature 424 443 1.7E-14 T 11-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 PRINTS PR01439 Cellulose synthase subunit A signature 498 519 1.7E-14 T 11-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 PRINTS PR01439 Cellulose synthase subunit A signature 61 86 1.7E-14 T 11-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 PRINTS PR01439 Cellulose synthase subunit A signature 33 53 1.7E-14 T 11-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 PRINTS PR01439 Cellulose synthase subunit A signature 355 381 1.7E-14 T 11-10-2018 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 UP12_17515 97b84996841ea40a5cf9b5c4ac94e6c1 758 Pfam PF00535 Glycosyl transferase family 2 109 278 1.9E-31 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_13790 1f2367c24266d5f268fdc5d506c05dd5 264 SUPERFAMILY SSF161098 68 259 1.03E-29 T 11-10-2018 IPR035906 MetI-like superfamily UP12_13790 1f2367c24266d5f268fdc5d506c05dd5 264 Gene3D G3DSA:1.10.3720.10 68 264 1.7E-24 T 11-10-2018 IPR035906 MetI-like superfamily UP12_13790 1f2367c24266d5f268fdc5d506c05dd5 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 261 3.2E-26 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 11-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 SUPERFAMILY SSF103491 2 420 8.5E-126 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 429 28.992 T 11-10-2018 IPR026593 Protein translocase subunit SecY UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PIRSF PIRSF004557 1 430 1.2E-123 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 1.9E-149 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 11-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 Gene3D G3DSA:1.10.3370.10 1 425 1.5E-154 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 6.4E-101 T 11-10-2018 UP12_00825 038c32591fd4747a35ba9ff3cacc27f5 430 Pfam PF00344 SecY translocase 68 413 7.5E-108 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 SUPERFAMILY SSF52418 73 334 1.24E-87 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 331 4.9E-126 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 38.385 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 SUPERFAMILY SSF47648 2 66 4.06E-15 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 Pfam PF00591 Glycosyl transferase family, a/b domain 72 322 3.9E-106 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 63 1.5E-15 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 Gene3D G3DSA:3.40.1030.10 70 339 1.3E-100 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_10175 fdeed75b9ac3935eb02022ee91927e79 340 Gene3D G3DSA:1.20.970.10 4 66 1.8E-17 T 11-10-2018 UP12_03255 dde54fef325605b1e46dd507d8ae747d 320 SUPERFAMILY SSF52540 10 285 1.43E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03255 dde54fef325605b1e46dd507d8ae747d 320 PIRSF PIRSF002849 3 315 1.5E-135 T 11-10-2018 UP12_03255 dde54fef325605b1e46dd507d8ae747d 320 Gene3D G3DSA:1.10.8.300 202 310 4.8E-35 T 11-10-2018 UP12_03255 dde54fef325605b1e46dd507d8ae747d 320 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 41 171 5.0E-66 T 11-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 UP12_03255 dde54fef325605b1e46dd507d8ae747d 320 Gene3D G3DSA:3.40.50.300 22 188 7.1E-46 T 11-10-2018 UP12_03705 c25ecc0382293056072873757c8f6f85 399 Gene3D G3DSA:1.20.1250.20 1 388 2.6E-32 T 11-10-2018 UP12_03705 c25ecc0382293056072873757c8f6f85 399 Pfam PF07690 Major Facilitator Superfamily 12 321 3.4E-14 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_03705 c25ecc0382293056072873757c8f6f85 399 SUPERFAMILY SSF103473 3 383 1.26E-28 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 11-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 309 1.8E-115 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 305 36.169 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 Gene3D G3DSA:3.40.50.170 1 206 7.2E-84 T 11-10-2018 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 SUPERFAMILY SSF50486 205 310 8.79E-31 T 11-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 SUPERFAMILY SSF53328 3 206 2.22E-65 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 Pfam PF02911 Formyl transferase, C-terminal domain 204 302 1.1E-29 T 11-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 Pfam PF00551 Formyl transferase 3 177 3.3E-39 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_07660 26184ad5b10c0f6cfbe85cb1d6a8fc8c 317 Gene3D G3DSA:3.10.25.10 207 313 8.0E-37 T 11-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Pfam PF02811 PHP domain 336 694 1.6E-52 T 11-10-2018 IPR004013 PHP domain GO:0003824 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 SMART SM00481 335 402 2.7E-25 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Pfam PF14579 Helix-hairpin-helix motif 1352 1429 3.2E-8 T 11-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 SUPERFAMILY SSF53098 420 877 4.86E-108 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:1.10.150.870 1288 1423 2.1E-52 T 11-10-2018 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Pfam PF11490 DNA polymerase III polC-type N-terminus II 97 207 3.6E-29 T 11-10-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:3.30.420.10 413 559 9.0E-45 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Pfam PF00929 Exonuclease 422 577 2.1E-43 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1437 463.27 T 11-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 825 1234 5.7E-98 T 11-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:1.10.150.700 1234 1286 9.0E-15 T 11-10-2018 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:1.10.150.700 1096 1185 4.3E-36 T 11-10-2018 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 230 1437 0.0 T 11-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:1.10.100.20 995 1042 2.2E-58 T 11-10-2018 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Pfam PF14480 DNA polymerase III polC-type N-terminus I 11 83 4.4E-23 T 11-10-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:3.20.20.140 561 806 6.2E-54 T 11-10-2018 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:2.40.50.140 219 319 4.4E-33 T 11-10-2018 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 413 638 1.5E-76 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 SUPERFAMILY SSF50249 234 319 8.57E-11 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:3.20.20.140 335 403 3.2E-10 T 11-10-2018 UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 SMART SM00479 420 587 7.2E-58 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UP12_08085 435d22cec454a8ba72774be4a4b8aaef 1437 Gene3D G3DSA:3.30.1900.20 973 1095 2.2E-58 T 11-10-2018 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 SUPERFAMILY SSF46548 2 163 3.3E-35 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 Gene3D G3DSA:3.50.50.60 152 277 9.7E-35 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 Gene3D G3DSA:3.50.50.60 289 493 7.9E-15 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 140 1.4E-21 T 11-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 475 7.2E-26 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 493 2.3E-251 T 11-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 Gene3D G3DSA:1.10.1060.10 7 151 4.3E-19 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 PRINTS PR00419 Adrenodoxin reductase family signature 295 309 1.3E-24 T 11-10-2018 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 1.3E-24 T 11-10-2018 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 1.3E-24 T 11-10-2018 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 1.3E-24 T 11-10-2018 UP12_09290 5f5e790197ceabbe5aca0fd8424dd56c 494 SUPERFAMILY SSF51971 151 421 4.18E-61 T 11-10-2018 UP12_15175 44139e157fbc6da51aa8570575b02c06 656 Gene3D G3DSA:2.130.10.10 162 263 4.1E-7 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_15175 44139e157fbc6da51aa8570575b02c06 656 Pfam PF07676 WD40-like Beta Propeller Repeat 19 31 0.23 T 11-10-2018 IPR011659 WD40-like Beta Propeller UP12_15175 44139e157fbc6da51aa8570575b02c06 656 Pfam PF07676 WD40-like Beta Propeller Repeat 57 85 0.04 T 11-10-2018 IPR011659 WD40-like Beta Propeller UP12_15175 44139e157fbc6da51aa8570575b02c06 656 Gene3D G3DSA:2.120.10.30 5 150 1.3E-19 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UP12_15175 44139e157fbc6da51aa8570575b02c06 656 SUPERFAMILY SSF82171 14 391 3.79E-34 T 11-10-2018 UP12_15175 44139e157fbc6da51aa8570575b02c06 656 Gene3D G3DSA:3.40.50.1820 401 656 1.1E-71 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_15175 44139e157fbc6da51aa8570575b02c06 656 Pfam PF00326 Prolyl oligopeptidase family 446 656 3.3E-54 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UP12_15175 44139e157fbc6da51aa8570575b02c06 656 SUPERFAMILY SSF53474 399 655 1.15E-66 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_06820 e494129c7b61274bb9dec8f74d929048 298 SUPERFAMILY SSF47240 1 293 7.84E-97 T 11-10-2018 IPR009078 Ferritin-like superfamily UP12_06820 e494129c7b61274bb9dec8f74d929048 298 Pfam PF05067 Manganese containing catalase 3 296 3.2E-94 T 11-10-2018 IPR007760 Manganese catalase UP12_06820 e494129c7b61274bb9dec8f74d929048 298 Gene3D G3DSA:1.20.1260.130 2 297 6.6E-109 T 11-10-2018 UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 SUPERFAMILY SSF90123 5 418 1.7E-74 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 Pfam PF00005 ABC transporter 445 594 1.1E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 Gene3D G3DSA:3.40.50.300 425 670 8.2E-86 T 11-10-2018 UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 ProSitePatterns PS00211 ABC transporters family signature. 566 580 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 SUPERFAMILY SSF52540 423 664 9.27E-84 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 Pfam PF00664 ABC transporter transmembrane region 148 385 9.0E-44 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 Gene3D G3DSA:1.20.1560.10 132 416 8.4E-71 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04950 96f9e4fc66325b11243f8cd20499d34e 671 SMART SM00382 454 646 2.4E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04800 c97722c5a478947e862374a6a2cf714e 553 Pfam PF01266 FAD dependent oxidoreductase 21 351 1.5E-53 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 Gene3D G3DSA:1.10.8.870 419 551 3.7E-40 T 11-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 SUPERFAMILY SSF54373 249 342 1.02E-10 T 11-10-2018 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 336 342 7.9E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 7.9E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 7.9E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 366 378 7.9E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 7.9E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 7.9E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 SUPERFAMILY SSF51905 8 237 1.37E-34 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_04800 c97722c5a478947e862374a6a2cf714e 553 Gene3D G3DSA:3.30.9.10 102 343 7.5E-137 T 11-10-2018 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 371 381 - T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 Gene3D G3DSA:3.50.50.60 18 379 7.5E-137 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_04800 c97722c5a478947e862374a6a2cf714e 553 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 403 530 2.0E-27 T 11-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_04800 c97722c5a478947e862374a6a2cf714e 553 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 Gene3D G3DSA:1.10.40.30 361 433 3.4E-194 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 44.238 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 2.5E-28 T 11-10-2018 IPR000362 Fumarate lyase family UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 2.5E-28 T 11-10-2018 IPR000362 Fumarate lyase family UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 2.5E-28 T 11-10-2018 IPR000362 Fumarate lyase family UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 2.5E-28 T 11-10-2018 IPR000362 Fumarate lyase family UP12_13180 1767e5878b64b217c55c92156a88a11a 457 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 456 1.7E-212 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 SUPERFAMILY SSF48557 4 456 2.83E-152 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 Pfam PF00206 Lyase 7 301 4.1E-74 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 6.8E-68 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 6.8E-68 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 6.8E-68 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 6.8E-68 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 6.8E-68 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 6.8E-68 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 Gene3D G3DSA:1.20.200.10 120 446 3.4E-194 T 11-10-2018 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UP12_13180 1767e5878b64b217c55c92156a88a11a 457 Gene3D G3DSA:1.10.275.10 26 230 3.4E-194 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal UP12_13180 1767e5878b64b217c55c92156a88a11a 457 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 3.0E-24 T 11-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_11240 76f73b134f483b38c3b058cbde1ec7b5 374 Gene3D G3DSA:3.40.630.10 84 374 2.0E-42 T 11-10-2018 UP12_11240 76f73b134f483b38c3b058cbde1ec7b5 374 SMART SM00631 85 366 4.6E-12 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UP12_11240 76f73b134f483b38c3b058cbde1ec7b5 374 Pfam PF00246 Zinc carboxypeptidase 95 296 3.4E-25 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UP12_11240 76f73b134f483b38c3b058cbde1ec7b5 374 SUPERFAMILY SSF53187 88 372 1.65E-44 T 11-10-2018 UP12_14585 f7834b7be8fb4d3d7d0b51a08083b2c1 146 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 10 145 2.8E-38 T 11-10-2018 IPR014986 Clostridium phage phiCD119, XkdN UP12_14585 f7834b7be8fb4d3d7d0b51a08083b2c1 146 Gene3D G3DSA:3.30.2220.30 14 134 1.4E-48 T 11-10-2018 IPR038559 Clostridium phage phiCD119, XkdN superfamily UP12_15725 17371e5f6b40992f8db97742b09dbc66 290 SUPERFAMILY SSF81345 7 258 2.75E-43 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15725 17371e5f6b40992f8db97742b09dbc66 290 Gene3D G3DSA:1.10.3470.10 37 264 5.6E-6 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15725 17371e5f6b40992f8db97742b09dbc66 290 Pfam PF00950 ABC 3 transport family 10 263 7.0E-81 T 11-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UP12_10940 391965ef1bf7da1117031ee617972c10 267 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 156 266 1.0E-58 T 11-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 UP12_10940 391965ef1bf7da1117031ee617972c10 267 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 2 267 1.9E-127 T 11-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 UP12_10940 391965ef1bf7da1117031ee617972c10 267 SUPERFAMILY SSF52172 2 129 2.28E-32 T 11-10-2018 IPR011006 CheY-like superfamily UP12_10940 391965ef1bf7da1117031ee617972c10 267 SMART SM00448 4 120 2.6E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_10940 391965ef1bf7da1117031ee617972c10 267 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 157 260 1.1E-44 T 11-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 UP12_10940 391965ef1bf7da1117031ee617972c10 267 PIRSF PIRSF002937 1 267 5.3E-132 T 11-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 UP12_10940 391965ef1bf7da1117031ee617972c10 267 Pfam PF00072 Response regulator receiver domain 6 120 7.6E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_10940 391965ef1bf7da1117031ee617972c10 267 Gene3D G3DSA:3.40.50.2300 1 149 4.3E-32 T 11-10-2018 UP12_10940 391965ef1bf7da1117031ee617972c10 267 SUPERFAMILY SSF46894 151 265 6.46E-48 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_10940 391965ef1bf7da1117031ee617972c10 267 Gene3D G3DSA:1.10.10.10 150 267 1.8E-54 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08705 eb0255517ea69488fe0e0615c09a4e5f 148 Gene3D G3DSA:3.30.310.250 1 148 5.8E-52 T 11-10-2018 IPR038449 SirA superfamily UP12_08705 eb0255517ea69488fe0e0615c09a4e5f 148 Pfam PF10747 Sporulation inhibitor of replication protein SirA 3 143 2.3E-47 T 11-10-2018 IPR019683 Sporulation inhibitor of replication protein SirA UP12_15975 64028da197c3d91d0ff039a960224651 271 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_15975 64028da197c3d91d0ff039a960224651 271 SUPERFAMILY SSF52540 3 243 1.63E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15975 64028da197c3d91d0ff039a960224651 271 SMART SM00382 38 229 4.4E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15975 64028da197c3d91d0ff039a960224651 271 Gene3D G3DSA:3.40.50.300 1 267 8.5E-70 T 11-10-2018 UP12_15975 64028da197c3d91d0ff039a960224651 271 TIGRFAM TIGR02769 nickel_nikE: nickel import ATP-binding protein NikE 3 266 1.1E-100 T 11-10-2018 IPR014137 Nickel import ATP-binding protein NikE GO:0005886|GO:0015413|GO:0015675|GO:0016151 UP12_15975 64028da197c3d91d0ff039a960224651 271 Pfam PF00005 ABC transporter 29 179 1.1E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 Gene3D G3DSA:1.10.287.130 268 344 3.7E-18 T 11-10-2018 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 SMART SM00387 393 499 2.1E-29 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 448 458 1.5E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 444 1.5E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 1.5E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 496 1.5E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 Gene3D G3DSA:3.30.565.10 345 497 2.3E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 Gene3D G3DSA:3.30.450.20 77 175 3.7E-60 T 11-10-2018 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 Pfam PF02743 Cache domain 47 210 1.7E-21 T 11-10-2018 IPR033479 Double Cache domain 1 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 SUPERFAMILY SSF103190 66 183 2.35E-11 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 Gene3D G3DSA:3.30.450.20 48 226 3.7E-60 T 11-10-2018 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 497 4.1E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 SMART SM00388 285 350 3.3E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 SUPERFAMILY SSF47384 273 350 3.92E-14 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 SUPERFAMILY SSF55874 353 496 4.32E-37 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06595 54350eb4315fc0fc47d556dd500295fb 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 287 348 6.3E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 Gene3D G3DSA:1.20.1560.10 14 353 3.6E-105 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 Pfam PF00664 ABC transporter transmembrane region 44 321 2.4E-57 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 SUPERFAMILY SSF52540 358 603 2.77E-91 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 Pfam PF00005 ABC transporter 384 532 1.4E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 ProSitePatterns PS00211 ABC transporters family signature. 504 518 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 SMART SM00382 392 584 8.1E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 Gene3D G3DSA:3.40.50.300 363 608 1.3E-89 T 11-10-2018 UP12_09310 08724b8309e2a5b4e4b4038a4b0c3fe9 609 SUPERFAMILY SSF90123 25 350 1.57E-87 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_16375 02274c16018b3601b0461d182b776e73 958 Gene3D G3DSA:1.20.1580.10 92 492 9.2E-253 T 11-10-2018 UP12_16375 02274c16018b3601b0461d182b776e73 958 Gene3D G3DSA:3.40.50.300 612 934 1.4E-146 T 11-10-2018 UP12_16375 02274c16018b3601b0461d182b776e73 958 SUPERFAMILY SSF52540 4 569 4.15E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16375 02274c16018b3601b0461d182b776e73 958 ProSitePatterns PS00211 ABC transporters family signature. 828 842 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16375 02274c16018b3601b0461d182b776e73 958 Gene3D G3DSA:1.10.8.280 286 403 9.2E-253 T 11-10-2018 UP12_16375 02274c16018b3601b0461d182b776e73 958 Gene3D G3DSA:3.30.190.20 132 241 9.2E-253 T 11-10-2018 UP12_16375 02274c16018b3601b0461d182b776e73 958 Hamap MF_00205 UvrABC system protein A [uvrA]. 3 938 23.571 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 UP12_16375 02274c16018b3601b0461d182b776e73 958 SMART SM00382 631 906 0.041 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16375 02274c16018b3601b0461d182b776e73 958 SMART SM00382 25 564 9.0 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16375 02274c16018b3601b0461d182b776e73 958 Gene3D G3DSA:1.20.1580.10 691 828 1.4E-146 T 11-10-2018 UP12_16375 02274c16018b3601b0461d182b776e73 958 Gene3D G3DSA:3.40.50.300 8 594 9.2E-253 T 11-10-2018 UP12_16375 02274c16018b3601b0461d182b776e73 958 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16375 02274c16018b3601b0461d182b776e73 958 Pfam PF00005 ABC transporter 622 858 7.8E-10 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16375 02274c16018b3601b0461d182b776e73 958 SUPERFAMILY SSF52540 613 912 1.95E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16375 02274c16018b3601b0461d182b776e73 958 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 923 0.0 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 SUPERFAMILY SSF46689 369 417 1.84E-9 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 Pfam PF12833 Helix-turn-helix domain 390 468 8.2E-23 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 SMART SM00448 2 116 9.5E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 Gene3D G3DSA:1.10.10.60 367 415 3.7E-15 T 11-10-2018 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 Pfam PF00072 Response regulator receiver domain 4 116 2.7E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 Gene3D G3DSA:1.10.10.60 416 471 1.7E-19 T 11-10-2018 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 SMART SM00342 383 466 2.2E-31 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 SUPERFAMILY SSF46689 420 469 1.08E-11 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 Gene3D G3DSA:3.40.50.12740 2 170 9.4E-38 T 11-10-2018 UP12_16770 c74312f00e05fec0ce992d1c606ed8ff 472 SUPERFAMILY SSF52172 1 134 3.27E-35 T 11-10-2018 IPR011006 CheY-like superfamily UP12_09635 c56afac1801865cca8bbf02042f34f5c 231 Pfam PF01048 Phosphorylase superfamily 16 217 5.8E-39 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UP12_09635 c56afac1801865cca8bbf02042f34f5c 231 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 11-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 UP12_09635 c56afac1801865cca8bbf02042f34f5c 231 SUPERFAMILY SSF53167 2 230 5.37E-88 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UP12_09635 c56afac1801865cca8bbf02042f34f5c 231 Gene3D G3DSA:3.40.50.1580 1 231 1.1E-72 T 11-10-2018 UP12_09635 c56afac1801865cca8bbf02042f34f5c 231 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 230 1.1E-111 T 11-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 UP12_09635 c56afac1801865cca8bbf02042f34f5c 231 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 231 45.211 T 11-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 UP12_07380 644d641fb17c1b2abd0aaa783df1aeb4 364 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 143 2.4E-50 T 11-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07380 644d641fb17c1b2abd0aaa783df1aeb4 364 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 33.742 T 11-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07380 644d641fb17c1b2abd0aaa783df1aeb4 364 Gene3D G3DSA:3.40.50.2000 4 352 3.5E-109 T 11-10-2018 UP12_07380 644d641fb17c1b2abd0aaa783df1aeb4 364 SUPERFAMILY SSF53756 1 361 4.35E-109 T 11-10-2018 UP12_07380 644d641fb17c1b2abd0aaa783df1aeb4 364 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 358 9.4E-109 T 11-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07380 644d641fb17c1b2abd0aaa783df1aeb4 364 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 353 5.9E-43 T 11-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 UP12_07380 644d641fb17c1b2abd0aaa783df1aeb4 364 Gene3D G3DSA:3.40.50.2000 164 346 3.5E-109 T 11-10-2018 UP12_12620 0a085ec9bcb5113371c96d6182b7a41c 106 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 4 94 6.2E-19 T 11-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor UP12_12620 0a085ec9bcb5113371c96d6182b7a41c 106 Gene3D G3DSA:2.40.10.270 2 105 3.8E-21 T 11-10-2018 IPR038666 Bacteriophage SPP1, head-tail adaptor superfamily UP12_12620 0a085ec9bcb5113371c96d6182b7a41c 106 Pfam PF05521 Phage head-tail joining protein 6 100 1.3E-24 T 11-10-2018 IPR008767 Bacteriophage SPP1, head-tail adaptor UP12_09315 6ac8b8c8886c19d6e3fd96ead94d5875 273 Gene3D G3DSA:3.20.80.10 195 271 3.7E-7 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_09315 6ac8b8c8886c19d6e3fd96ead94d5875 273 Gene3D G3DSA:1.10.1660.10 8 133 1.3E-25 T 11-10-2018 UP12_09315 6ac8b8c8886c19d6e3fd96ead94d5875 273 SUPERFAMILY SSF46955 11 119 5.13E-23 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_09315 6ac8b8c8886c19d6e3fd96ead94d5875 273 SUPERFAMILY SSF55136 154 268 2.12E-12 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_09315 6ac8b8c8886c19d6e3fd96ead94d5875 273 Pfam PF13411 MerR HTH family regulatory protein 12 76 3.6E-12 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_09315 6ac8b8c8886c19d6e3fd96ead94d5875 273 SMART SM00422 9 78 4.2E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_07705 50f70d91c057b368320a34750aeb54bf 62 Pfam PF00830 Ribosomal L28 family 3 58 2.4E-21 T 11-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07705 50f70d91c057b368320a34750aeb54bf 62 SUPERFAMILY SSF143800 1 60 1.08E-23 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07705 50f70d91c057b368320a34750aeb54bf 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 4.9E-23 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_07705 50f70d91c057b368320a34750aeb54bf 62 Gene3D G3DSA:2.30.170.40 19 62 7.0E-19 T 11-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07705 50f70d91c057b368320a34750aeb54bf 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 19.981 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_11575 73d8822c2b688a41e6fd42f2752fdd14 379 Pfam PF04055 Radical SAM superfamily 6 176 8.2E-22 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_11575 73d8822c2b688a41e6fd42f2752fdd14 379 SMART SM00729 1 222 2.4E-61 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_11575 73d8822c2b688a41e6fd42f2752fdd14 379 Pfam PF06969 HemN C-terminal domain 302 364 2.6E-15 T 11-10-2018 IPR010723 HemN, C-terminal UP12_11575 73d8822c2b688a41e6fd42f2752fdd14 379 Gene3D G3DSA:3.80.30.20 2 301 1.4E-101 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UP12_11575 73d8822c2b688a41e6fd42f2752fdd14 379 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 3 363 3.3E-152 T 11-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 UP12_11575 73d8822c2b688a41e6fd42f2752fdd14 379 SUPERFAMILY SSF102114 4 376 1.96E-117 T 11-10-2018 UP12_07015 22749a653016bfa4c08de9d35bf2df38 278 Gene3D G3DSA:3.10.490.10 123 278 2.6E-61 T 11-10-2018 UP12_07015 22749a653016bfa4c08de9d35bf2df38 278 Pfam PF13772 AIG2-like family 188 257 6.9E-8 T 11-10-2018 UP12_07015 22749a653016bfa4c08de9d35bf2df38 278 Gene3D G3DSA:3.10.490.10 3 120 3.6E-30 T 11-10-2018 UP12_07015 22749a653016bfa4c08de9d35bf2df38 278 SUPERFAMILY SSF110857 129 255 6.28E-19 T 11-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily UP12_07015 22749a653016bfa4c08de9d35bf2df38 278 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 6 117 2.3E-22 T 11-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like UP12_07015 22749a653016bfa4c08de9d35bf2df38 278 SUPERFAMILY SSF110857 5 123 1.27E-22 T 11-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 Gene3D G3DSA:3.30.420.40 7 358 1.2E-159 T 11-10-2018 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 Hamap MF_00542 Probable butyrate kinase [buk]. 1 373 173.522 T 11-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 Pfam PF00871 Acetokinase family 8 342 1.5E-70 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 PIRSF PIRSF036458 4 359 3.0E-174 T 11-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 Gene3D G3DSA:3.30.420.40 140 335 1.2E-159 T 11-10-2018 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 PRINTS PR00471 Acetate kinase family signature 8 19 4.5E-15 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 PRINTS PR00471 Acetate kinase family signature 300 316 4.5E-15 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 PRINTS PR00471 Acetate kinase family signature 277 290 4.5E-15 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 PRINTS PR00471 Acetate kinase family signature 182 203 4.5E-15 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 7 356 1.1E-175 T 11-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 SUPERFAMILY SSF53067 6 175 6.28E-73 T 11-10-2018 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 SUPERFAMILY SSF53067 120 349 2.85E-55 T 11-10-2018 UP12_10900 de708b9e3d3692e7fdd7f3800be69c12 373 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 182 199 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 Gene3D G3DSA:3.40.50.720 1 259 1.5E-68 T 11-10-2018 UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 SUPERFAMILY SSF51735 7 258 3.97E-73 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06730 83b633092f3ac4860f6b9a40a9756ae9 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 3.7E-54 T 11-10-2018 UP12_04755 f057e4fe4eafedf443a68a562b1b8574 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 3.3E-32 T 11-10-2018 UP12_04755 f057e4fe4eafedf443a68a562b1b8574 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 58 184 1.9E-16 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UP12_04755 f057e4fe4eafedf443a68a562b1b8574 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 63 159 6.8E-6 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UP12_04755 f057e4fe4eafedf443a68a562b1b8574 221 Gene3D G3DSA:1.10.150.240 15 84 1.2E-52 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UP12_04755 f057e4fe4eafedf443a68a562b1b8574 221 SUPERFAMILY SSF56784 2 207 4.6E-46 T 11-10-2018 IPR036412 HAD-like superfamily UP12_04755 f057e4fe4eafedf443a68a562b1b8574 221 Gene3D G3DSA:3.40.50.1000 3 202 1.2E-52 T 11-10-2018 IPR023214 HAD superfamily UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 SUPERFAMILY SSF54791 208 304 7.03E-16 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 SUPERFAMILY SSF109604 316 467 1.03E-30 T 11-10-2018 UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 SMART SM00471 332 438 3.9E-14 T 11-10-2018 IPR003607 HD/PDEase domain UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 Gene3D G3DSA:3.30.1370.10 208 305 1.2E-8 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 Pfam PF01966 HD domain 337 428 1.8E-18 T 11-10-2018 IPR006674 HD domain UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 SMART SM00322 208 275 1.1E-6 T 11-10-2018 IPR004087 K Homology domain GO:0003676 UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 Gene3D G3DSA:1.10.3210.10 319 473 1.3E-19 T 11-10-2018 UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 Pfam PF00013 KH domain 213 267 3.4E-6 T 11-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 TIGRFAM TIGR00277 HDIG: HDIG domain 332 409 3.0E-26 T 11-10-2018 IPR006675 HDIG domain UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 Pfam PF12072 Domain of unknown function (DUF3552) 7 205 2.7E-77 T 11-10-2018 IPR022711 Ribonuclease Y, N-terminal UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 Hamap MF_00335 Ribonuclease Y [rny]. 5 520 25.84 T 11-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 UP12_08300 b0436ec38766f860c1e4b47ec28539d9 520 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 8 520 1.7E-247 T 11-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 UP12_11550 c9a82afb5493cea90365166d5a66ce95 311 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.599 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 UP12_11550 c9a82afb5493cea90365166d5a66ce95 311 Gene3D G3DSA:3.40.50.150 116 311 4.9E-62 T 11-10-2018 UP12_11550 c9a82afb5493cea90365166d5a66ce95 311 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 1.2E-107 T 11-10-2018 UP12_11550 c9a82afb5493cea90365166d5a66ce95 311 PIRSF PIRSF000401 1 311 4.5E-109 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 UP12_11550 c9a82afb5493cea90365166d5a66ce95 311 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 2.1E-108 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 UP12_11550 c9a82afb5493cea90365166d5a66ce95 311 SUPERFAMILY SSF53335 89 310 4.33E-46 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_03610 f54d19b0110873c973fbf229dffd2615 458 Gene3D G3DSA:3.40.50.150 85 452 1.5E-130 T 11-10-2018 UP12_03610 f54d19b0110873c973fbf229dffd2615 458 Pfam PF01938 TRAM domain 8 62 1.1E-11 T 11-10-2018 IPR002792 TRAM domain UP12_03610 f54d19b0110873c973fbf229dffd2615 458 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 440 450 - T 11-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site UP12_03610 f54d19b0110873c973fbf229dffd2615 458 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 388 419 - T 11-10-2018 IPR030390 RNA methyltransferase TrmA, active site UP12_03610 f54d19b0110873c973fbf229dffd2615 458 SUPERFAMILY SSF53335 72 453 2.15E-94 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_03610 f54d19b0110873c973fbf229dffd2615 458 Gene3D G3DSA:3.40.1350.30 134 289 1.5E-130 T 11-10-2018 UP12_03610 f54d19b0110873c973fbf229dffd2615 458 Gene3D G3DSA:2.40.50.140 1 83 1.4E-22 T 11-10-2018 UP12_03610 f54d19b0110873c973fbf229dffd2615 458 SUPERFAMILY SSF50249 3 64 1.14E-16 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_03610 f54d19b0110873c973fbf229dffd2615 458 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 279 453 3.4E-22 T 11-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 UP12_03610 f54d19b0110873c973fbf229dffd2615 458 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 20 450 8.2E-199 T 11-10-2018 UP12_05495 e2b511070fe1f52468885f30ae7395eb 163 Gene3D G3DSA:3.30.70.990 12 101 1.3E-60 T 11-10-2018 IPR035570 UPF0234, N-terminal UP12_05495 e2b511070fe1f52468885f30ae7395eb 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 1.7E-61 T 11-10-2018 IPR007551 Protein of unknown function DUF520 UP12_05495 e2b511070fe1f52468885f30ae7395eb 163 SUPERFAMILY SSF89963 92 163 1.75E-25 T 11-10-2018 IPR036183 YajQ-like superfamily UP12_05495 e2b511070fe1f52468885f30ae7395eb 163 Gene3D G3DSA:3.30.70.860 6 163 1.3E-60 T 11-10-2018 IPR035571 UPF0234-like, C-terminal UP12_05495 e2b511070fe1f52468885f30ae7395eb 163 SUPERFAMILY SSF89963 6 89 6.02E-30 T 11-10-2018 IPR036183 YajQ-like superfamily UP12_05495 e2b511070fe1f52468885f30ae7395eb 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.584 T 11-10-2018 IPR007551 Protein of unknown function DUF520 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 Gene3D G3DSA:3.40.50.2020 153 293 5.1E-126 T 11-10-2018 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 317 4.2E-130 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 10 317 50.997 T 11-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 6.6E-52 T 11-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 SUPERFAMILY SSF53271 75 309 3.33E-67 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 Gene3D G3DSA:3.40.50.2020 13 305 5.1E-126 T 11-10-2018 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 11-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 8.4E-26 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 UP12_00320 498dc9767d386208f90d7264b0e40d3c 317 SMART SM01400 10 126 3.6E-82 T 11-10-2018 UP12_04785 d9409362b3705bf07d554b660bb4ea15 185 Gene3D G3DSA:3.20.20.400 1 185 9.5E-72 T 11-10-2018 IPR035928 GlpP-like superfamily UP12_04785 d9409362b3705bf07d554b660bb4ea15 185 SUPERFAMILY SSF110391 7 181 6.02E-63 T 11-10-2018 IPR035928 GlpP-like superfamily UP12_04785 d9409362b3705bf07d554b660bb4ea15 185 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 8 180 3.9E-65 T 11-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 UP12_04785 d9409362b3705bf07d554b660bb4ea15 185 PIRSF PIRSF016897 1 185 4.1E-68 T 11-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 UP12_12165 3f5ca54c1a829f7a20db3dc037fdcda8 214 Gene3D G3DSA:1.10.510.10 3 174 7.9E-10 T 11-10-2018 UP12_12165 3f5ca54c1a829f7a20db3dc037fdcda8 214 SUPERFAMILY SSF56112 30 161 4.92E-19 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_03785 34721387aa9f011648cb00b6596e1ec0 357 SMART SM00028 310 343 18.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_03785 34721387aa9f011648cb00b6596e1ec0 357 SMART SM00028 266 299 6.5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_03785 34721387aa9f011648cb00b6596e1ec0 357 SUPERFAMILY SSF48452 195 349 7.59E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_03785 34721387aa9f011648cb00b6596e1ec0 357 Gene3D G3DSA:1.25.40.10 187 355 1.9E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_03785 34721387aa9f011648cb00b6596e1ec0 357 Gene3D G3DSA:3.90.550.10 1 179 1.3E-27 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_03785 34721387aa9f011648cb00b6596e1ec0 357 Pfam PF00535 Glycosyl transferase family 2 5 123 6.2E-22 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_03785 34721387aa9f011648cb00b6596e1ec0 357 SUPERFAMILY SSF53448 3 155 1.37E-28 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_14055 5e9b028d98280e06c1f098e48aa7c81a 191 Gene3D G3DSA:1.10.1760.20 4 189 2.3E-53 T 11-10-2018 UP12_14055 5e9b028d98280e06c1f098e48aa7c81a 191 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 10 185 2.9E-59 T 11-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 UP12_14055 5e9b028d98280e06c1f098e48aa7c81a 191 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 8 187 1.2E-49 T 11-10-2018 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 UP12_09485 4f6e86cc832069174cde1cd321573203 166 Gene3D G3DSA:1.20.120.910 2 125 1.2E-25 T 11-10-2018 UP12_09485 4f6e86cc832069174cde1cd321573203 166 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 89 113 - T 11-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site UP12_09485 4f6e86cc832069174cde1cd321573203 166 SUPERFAMILY SSF109635 3 85 9.81E-9 T 11-10-2018 IPR037187 DksA, N-terminal domain superfamily UP12_09485 4f6e86cc832069174cde1cd321573203 166 SUPERFAMILY SSF57716 86 120 1.04E-6 T 11-10-2018 UP12_09485 4f6e86cc832069174cde1cd321573203 166 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 84 113 3.8E-9 T 11-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Pfam PF13426 PAS domain 37 133 5.3E-8 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Pfam PF13426 PAS domain 158 255 2.8E-6 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Pfam PF13188 PAS domain 389 430 1.8E-7 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SUPERFAMILY SSF55785 253 364 1.68E-19 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SMART SM00387 617 724 3.2E-31 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 265 383 2.7E-12 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 384 502 2.7E-13 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 145 263 6.0E-12 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Gene3D G3DSA:3.30.450.20 269 384 3.7E-18 T 11-10-2018 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Gene3D G3DSA:3.30.450.20 143 268 2.5E-16 T 11-10-2018 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Gene3D G3DSA:3.30.565.10 577 731 1.5E-45 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Pfam PF00989 PAS fold 268 364 6.8E-11 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SUPERFAMILY SSF47384 506 573 6.67E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Gene3D G3DSA:1.10.287.130 500 574 1.7E-15 T 11-10-2018 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Gene3D G3DSA:3.30.450.20 27 134 6.8E-14 T 11-10-2018 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 619 723 2.3E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Gene3D G3DSA:3.30.450.20 385 499 3.0E-18 T 11-10-2018 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SUPERFAMILY SSF55785 373 494 5.32E-17 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 708 721 2.3E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 684 702 2.3E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 673 683 2.3E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 655 669 2.3E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SUPERFAMILY SSF55785 12 133 1.54E-13 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SMART SM00388 511 575 1.1E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SUPERFAMILY SSF55785 132 254 6.46E-16 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SUPERFAMILY SSF55874 569 724 7.33E-40 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SMART SM00091 26 92 0.0043 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SMART SM00091 147 213 4.6E-7 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SMART SM00091 268 333 1.3E-9 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 SMART SM00091 388 454 1.1E-5 T 11-10-2018 IPR000014 PAS domain UP12_06545 e090e3ca59da5506e736d4f16dae64cf 731 Pfam PF00512 His Kinase A (phospho-acceptor) domain 513 573 4.5E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 88 1.9E-9 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 312 1.6E-107 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 PIRSF PIRSF004491 3 319 3.6E-110 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 Pfam PF01687 Riboflavin kinase 186 310 2.4E-36 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 Pfam PF06574 FAD synthetase 14 168 3.9E-51 T 11-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 Gene3D G3DSA:3.40.50.620 6 187 1.5E-59 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 SUPERFAMILY SSF52374 20 185 3.26E-32 T 11-10-2018 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 SUPERFAMILY SSF82114 175 314 3.49E-45 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 Gene3D G3DSA:2.40.30.30 188 321 1.8E-41 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 UP12_08150 c097504a7a9f2c276c60a1afd87acb91 321 SMART SM00904 185 312 1.4E-61 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 UP12_08535 5c2c41394464648053e57c990a9f773e 157 SUPERFAMILY SSF160424 3 155 1.06E-47 T 11-10-2018 IPR036170 Probable antitoxin YezG superfamily UP12_08535 5c2c41394464648053e57c990a9f773e 157 TIGRFAM TIGR01741 staph_tand_hypo: conserved hypothetical protein 1 152 8.8E-31 T 11-10-2018 IPR006728 Protein of unknown function DUF600 UP12_08535 5c2c41394464648053e57c990a9f773e 157 Pfam PF04634 Protein of unknown function, DUF600 7 150 6.5E-52 T 11-10-2018 IPR006728 Protein of unknown function DUF600 UP12_08535 5c2c41394464648053e57c990a9f773e 157 Gene3D G3DSA:3.30.500.20 2 118 1.9E-38 T 11-10-2018 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 Gene3D G3DSA:3.30.1390.30 189 260 8.1E-44 T 11-10-2018 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 43 161 1.2E-31 T 11-10-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 Pfam PF03717 Penicillin-binding Protein dimerisation domain 168 326 2.4E-29 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 SUPERFAMILY SSF56601 348 677 2.82E-79 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 Gene3D G3DSA:3.40.710.10 347 679 1.1E-79 T 11-10-2018 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 SUPERFAMILY SSF56519 161 347 1.09E-33 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 Gene3D G3DSA:3.90.1310.10 169 342 8.1E-44 T 11-10-2018 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 SUPERFAMILY SSF54427 45 159 4.21E-28 T 11-10-2018 IPR032710 NTF2-like domain superfamily UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 Pfam PF00905 Penicillin binding protein transpeptidase domain 365 664 2.5E-65 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_03745 67a39963eac2d0f50fd3e14cabd7947a 679 Gene3D G3DSA:3.10.450.100 38 156 8.1E-16 T 11-10-2018 UP12_19020 92bbea6dd5afb813f676ea13da57bf29 404 TIGRFAM TIGR00896 CynX: cyanate transporter 21 375 4.3E-128 T 11-10-2018 IPR004747 Cyanate transport system protein GO:0016021 UP12_19020 92bbea6dd5afb813f676ea13da57bf29 404 Gene3D G3DSA:1.20.1250.20 13 200 2.4E-16 T 11-10-2018 UP12_19020 92bbea6dd5afb813f676ea13da57bf29 404 Pfam PF07690 Major Facilitator Superfamily 35 357 6.5E-25 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_19020 92bbea6dd5afb813f676ea13da57bf29 404 Gene3D G3DSA:1.20.1250.20 209 396 3.3E-19 T 11-10-2018 UP12_19020 92bbea6dd5afb813f676ea13da57bf29 404 SUPERFAMILY SSF103473 11 395 9.29E-48 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_16195 507e81cd9325a9cdfa0bf5353464bcc7 290 SUPERFAMILY SSF53697 117 285 5.12E-19 T 11-10-2018 UP12_16195 507e81cd9325a9cdfa0bf5353464bcc7 290 Gene3D G3DSA:3.40.50.10490 104 286 5.9E-26 T 11-10-2018 UP12_16195 507e81cd9325a9cdfa0bf5353464bcc7 290 Pfam PF01380 SIS domain 138 260 3.6E-15 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_16195 507e81cd9325a9cdfa0bf5353464bcc7 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 14 77 2.8E-18 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_16195 507e81cd9325a9cdfa0bf5353464bcc7 290 Gene3D G3DSA:1.10.10.10 4 78 2.4E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16195 507e81cd9325a9cdfa0bf5353464bcc7 290 SUPERFAMILY SSF46689 15 80 4.3E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_02975 37d12a8dad948122e3f1f22b573f3d64 157 SUPERFAMILY SSF55729 1 138 1.23E-27 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_02975 37d12a8dad948122e3f1f22b573f3d64 157 Pfam PF00583 Acetyltransferase (GNAT) family 34 132 2.4E-16 T 11-10-2018 IPR000182 GNAT domain UP12_02975 37d12a8dad948122e3f1f22b573f3d64 157 Gene3D G3DSA:3.40.630.30 1 147 1.8E-27 T 11-10-2018 UP12_14580 2620116d7ad3dc23d62b44708af9a8d0 1373 Gene3D G3DSA:1.10.530.10 1135 1236 3.1E-5 T 11-10-2018 UP12_14580 2620116d7ad3dc23d62b44708af9a8d0 1373 Pfam PF01464 Transglycosylase SLT domain 1142 1267 5.0E-17 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 UP12_14580 2620116d7ad3dc23d62b44708af9a8d0 1373 SUPERFAMILY SSF53955 1156 1227 3.25E-10 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_18655 4bfdb00a2b663ec9917b77041fe864c4 68 Pfam PF01381 Helix-turn-helix 5 57 2.0E-11 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_18655 4bfdb00a2b663ec9917b77041fe864c4 68 SUPERFAMILY SSF47413 2 64 5.63E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_18655 4bfdb00a2b663ec9917b77041fe864c4 68 Gene3D G3DSA:1.10.260.40 1 65 2.3E-21 T 11-10-2018 UP12_18655 4bfdb00a2b663ec9917b77041fe864c4 68 SMART SM00530 4 59 1.4E-10 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_13665 225303382499d0893e72e0bc61f98219 267 Gene3D G3DSA:3.30.750.24 149 262 7.1E-27 T 11-10-2018 IPR036513 STAS domain superfamily UP12_13665 225303382499d0893e72e0bc61f98219 267 SUPERFAMILY SSF52091 150 258 2.75E-12 T 11-10-2018 IPR036513 STAS domain superfamily UP12_13665 225303382499d0893e72e0bc61f98219 267 Pfam PF01740 STAS domain 154 256 5.3E-7 T 11-10-2018 IPR002645 STAS domain UP12_13665 225303382499d0893e72e0bc61f98219 267 Pfam PF13426 PAS domain 27 130 8.2E-20 T 11-10-2018 IPR000014 PAS domain UP12_13665 225303382499d0893e72e0bc61f98219 267 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 137 3.2E-19 T 11-10-2018 IPR000014 PAS domain UP12_13665 225303382499d0893e72e0bc61f98219 267 SMART SM00091 14 83 1.0E-4 T 11-10-2018 IPR000014 PAS domain UP12_13665 225303382499d0893e72e0bc61f98219 267 SMART SM00086 89 131 1.3E-8 T 11-10-2018 IPR001610 PAC motif UP12_13665 225303382499d0893e72e0bc61f98219 267 SUPERFAMILY SSF55785 21 131 2.9E-25 T 11-10-2018 IPR035965 PAS domain superfamily UP12_13665 225303382499d0893e72e0bc61f98219 267 Gene3D G3DSA:3.30.450.20 9 148 6.8E-49 T 11-10-2018 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 SUPERFAMILY SSF50615 1 82 6.8E-27 T 11-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 SUPERFAMILY SSF52540 84 354 5.13E-87 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 5.5E-66 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 1.9E-23 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 Gene3D G3DSA:3.40.50.300 84 352 2.3E-112 T 11-10-2018 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 469 57.455 T 11-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 Gene3D G3DSA:2.40.10.170 1 82 7.5E-32 T 11-10-2018 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 SMART SM00382 150 413 2.1E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 SUPERFAMILY SSF47917 354 469 2.59E-52 T 11-10-2018 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 469 8.8E-258 T 11-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 UP12_17180 2680a9b0630ab4f8fcada6e4c59d46c8 473 Gene3D G3DSA:1.10.1140.10 354 473 1.7E-57 T 11-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_13190 c0f2153a89dda0ac4f7aab55c5362bd8 171 SMART SM00852 17 162 8.7E-25 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_13190 c0f2153a89dda0ac4f7aab55c5362bd8 171 SUPERFAMILY SSF53218 9 166 1.44E-40 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily UP12_13190 c0f2153a89dda0ac4f7aab55c5362bd8 171 PIRSF PIRSF006443 1 170 1.2E-64 T 11-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 UP12_13190 c0f2153a89dda0ac4f7aab55c5362bd8 171 Gene3D G3DSA:3.40.980.10 1 169 7.0E-48 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily UP12_13190 c0f2153a89dda0ac4f7aab55c5362bd8 171 Pfam PF00994 Probable molybdopterin binding domain 18 161 1.2E-33 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_13190 c0f2153a89dda0ac4f7aab55c5362bd8 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 15 157 7.5E-36 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_13190 c0f2153a89dda0ac4f7aab55c5362bd8 171 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 75 88 - T 11-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 UP12_02830 329feddf3deb1d99bbac2a245fb39832 264 SUPERFAMILY SSF53474 2 258 3.75E-43 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02830 329feddf3deb1d99bbac2a245fb39832 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 2.7E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_02830 329feddf3deb1d99bbac2a245fb39832 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 2.7E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_02830 329feddf3deb1d99bbac2a245fb39832 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 2.7E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_02830 329feddf3deb1d99bbac2a245fb39832 264 Pfam PF12146 Serine aminopeptidase, S33 14 244 1.4E-17 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 UP12_02830 329feddf3deb1d99bbac2a245fb39832 264 Gene3D G3DSA:3.40.50.1820 1 263 2.9E-55 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_12250 d37eb1c603d3a9261fc4239476f9aca1 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.4E-40 T 11-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12250 d37eb1c603d3a9261fc4239476f9aca1 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.129 T 11-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12250 d37eb1c603d3a9261fc4239476f9aca1 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 11-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_12250 d37eb1c603d3a9261fc4239476f9aca1 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 2.2E-40 T 11-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12250 d37eb1c603d3a9261fc4239476f9aca1 102 SUPERFAMILY SSF141091 1 101 6.28E-39 T 11-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_06135 bd7c72afcc1c67e3c5c5758362a2684c 274 Gene3D G3DSA:1.10.287.950 102 274 2.8E-36 T 11-10-2018 UP12_06135 bd7c72afcc1c67e3c5c5758362a2684c 274 SUPERFAMILY SSF58104 109 272 1.31E-37 T 11-10-2018 UP12_06135 bd7c72afcc1c67e3c5c5758362a2684c 274 SUPERFAMILY SSF103190 20 108 1.22E-7 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_06135 bd7c72afcc1c67e3c5c5758362a2684c 274 SMART SM00283 109 272 0.0015 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_06135 bd7c72afcc1c67e3c5c5758362a2684c 274 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 145 271 1.7E-27 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_03515 2c4167f2802ed56f1f4892f3bff9543a 351 SUPERFAMILY SSF55729 178 303 6.34E-7 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_03515 2c4167f2802ed56f1f4892f3bff9543a 351 Pfam PF13419 Haloacid dehalogenase-like hydrolase 25 107 3.9E-8 T 11-10-2018 UP12_03515 2c4167f2802ed56f1f4892f3bff9543a 351 Gene3D G3DSA:3.40.50.1000 4 148 2.3E-37 T 11-10-2018 IPR023214 HAD superfamily UP12_03515 2c4167f2802ed56f1f4892f3bff9543a 351 SUPERFAMILY SSF56784 1 115 2.67E-18 T 11-10-2018 IPR036412 HAD-like superfamily UP12_03515 2c4167f2802ed56f1f4892f3bff9543a 351 TIGRFAM TIGR01686 FkbH: FkbH domain 5 311 2.6E-84 T 11-10-2018 IPR010037 FkbH domain UP12_03515 2c4167f2802ed56f1f4892f3bff9543a 351 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 6 113 4.0E-19 T 11-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC UP12_03515 2c4167f2802ed56f1f4892f3bff9543a 351 Gene3D G3DSA:3.40.630.30 177 317 6.5E-7 T 11-10-2018 UP12_05985 a712ddd1167c63d3bd08d9f49b61da87 276 Pfam PF03629 Carbohydrate esterase, sialic acid-specific acetylesterase 3 223 5.2E-55 T 11-10-2018 IPR005181 Sialate O-acetylesterase domain UP12_05985 a712ddd1167c63d3bd08d9f49b61da87 276 SUPERFAMILY SSF52266 2 269 9.36E-81 T 11-10-2018 UP12_05985 a712ddd1167c63d3bd08d9f49b61da87 276 Gene3D G3DSA:3.40.50.1110 1 247 3.2E-88 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_06555 77543dcd2bdb9606a1d58c7be603c42a 353 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 9 336 1.4E-137 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 UP12_06555 77543dcd2bdb9606a1d58c7be603c42a 353 SUPERFAMILY SSF100950 5 343 2.43E-117 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_06555 77543dcd2bdb9606a1d58c7be603c42a 353 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 7 347 38.059 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 UP12_06555 77543dcd2bdb9606a1d58c7be603c42a 353 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 37 336 1.8E-132 T 11-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 UP12_06555 77543dcd2bdb9606a1d58c7be603c42a 353 Pfam PF01008 Initiation factor 2 subunit family 49 336 1.9E-92 T 11-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 UP12_06555 77543dcd2bdb9606a1d58c7be603c42a 353 Gene3D G3DSA:3.40.50.10470 149 351 2.7E-70 T 11-10-2018 UP12_06555 77543dcd2bdb9606a1d58c7be603c42a 353 Gene3D G3DSA:1.20.120.420 1 148 6.6E-51 T 11-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 UP12_07635 8be009fc89a0824266b792d32b765b6b 204 SMART SM00072 4 187 5.1E-80 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit UP12_07635 8be009fc89a0824266b792d32b765b6b 204 Pfam PF00625 Guanylate kinase 7 184 4.2E-55 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit UP12_07635 8be009fc89a0824266b792d32b765b6b 204 Gene3D G3DSA:3.30.63.10 37 96 5.9E-69 T 11-10-2018 UP12_07635 8be009fc89a0824266b792d32b765b6b 204 Gene3D G3DSA:3.40.50.300 9 183 5.9E-69 T 11-10-2018 UP12_07635 8be009fc89a0824266b792d32b765b6b 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 11-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 UP12_07635 8be009fc89a0824266b792d32b765b6b 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 37.237 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 UP12_07635 8be009fc89a0824266b792d32b765b6b 204 SUPERFAMILY SSF52540 3 190 2.54E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07635 8be009fc89a0824266b792d32b765b6b 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 4.2E-74 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 SUPERFAMILY SSF58104 252 580 3.92E-61 T 11-10-2018 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 Pfam PF17200 Single Cache domain 2 42 202 5.6E-38 T 11-10-2018 IPR033480 Single Cache domain 2 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 SMART SM00304 225 277 2.5E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 SMART SM01049 39 139 2.4E-6 T 11-10-2018 IPR033480 Single Cache domain 2 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 Gene3D G3DSA:1.10.287.950 276 581 5.0E-58 T 11-10-2018 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 SMART SM00283 306 567 8.7E-50 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 Gene3D G3DSA:1.10.8.500 229 275 7.4E-7 T 11-10-2018 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 355 526 1.9E-32 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 Pfam PF00672 HAMP domain 229 273 8.1E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_02215 c141983e8580fd4188e2ff6785d8bff8 582 Gene3D G3DSA:3.30.450.20 38 202 1.2E-15 T 11-10-2018 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 Gene3D G3DSA:1.20.59.10 8 92 1.2E-27 T 11-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 SMART SM00830 10 89 2.7E-19 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 Pfam PF01817 Chorismate mutase type II 10 87 2.0E-17 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 Gene3D G3DSA:3.20.20.70 93 355 2.3E-101 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 SUPERFAMILY SSF51569 31 353 4.67E-103 T 11-10-2018 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 102 1.9E-49 T 11-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 Pfam PF00793 DAHP synthetase I family 111 346 1.4E-82 T 11-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 UP12_13420 c15969fca3c8d0c653539ab90cb06124 358 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 350 2.6E-121 T 11-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 UP12_03410 3e8bee6ab20f769bb4910f1e6ccb008f 454 Pfam PF00202 Aminotransferase class-III 18 437 1.5E-101 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_03410 3e8bee6ab20f769bb4910f1e6ccb008f 454 Gene3D G3DSA:3.40.640.10 51 326 2.3E-144 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_03410 3e8bee6ab20f769bb4910f1e6ccb008f 454 PIRSF PIRSF000521 19 440 2.0E-35 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_03410 3e8bee6ab20f769bb4910f1e6ccb008f 454 SUPERFAMILY SSF53383 12 439 3.88E-116 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_03410 3e8bee6ab20f769bb4910f1e6ccb008f 454 Gene3D G3DSA:3.90.1150.10 17 437 2.3E-144 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_03410 3e8bee6ab20f769bb4910f1e6ccb008f 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_04700 75283960bee4f351c46d6d171911b62d 361 Pfam PF00990 Diguanylate cyclase, GGDEF domain 192 351 1.3E-45 T 11-10-2018 IPR000160 GGDEF domain UP12_04700 75283960bee4f351c46d6d171911b62d 361 SUPERFAMILY SSF55073 197 354 1.33E-45 T 11-10-2018 IPR029787 Nucleotide cyclase UP12_04700 75283960bee4f351c46d6d171911b62d 361 SMART SM00267 181 355 1.1E-54 T 11-10-2018 IPR000160 GGDEF domain UP12_04700 75283960bee4f351c46d6d171911b62d 361 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 189 353 1.0E-49 T 11-10-2018 IPR000160 GGDEF domain UP12_04700 75283960bee4f351c46d6d171911b62d 361 Gene3D G3DSA:3.30.70.270 188 359 3.3E-51 T 11-10-2018 UP12_04700 75283960bee4f351c46d6d171911b62d 361 Pfam PF07694 5TMR of 5TMR-LYT 22 150 1.9E-12 T 11-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 UP12_11465 f68d7d8582abb1b92133bcb767183289 256 Pfam PF11967 Recombination protein O N terminal 1 77 2.3E-27 T 11-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal UP12_11465 f68d7d8582abb1b92133bcb767183289 256 TIGRFAM TIGR00613 reco: DNA repair protein RecO 3 243 1.7E-87 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UP12_11465 f68d7d8582abb1b92133bcb767183289 256 Gene3D G3DSA:1.20.1440.120 88 225 5.1E-21 T 11-10-2018 UP12_11465 f68d7d8582abb1b92133bcb767183289 256 SUPERFAMILY SSF50249 1 77 1.88E-20 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_11465 f68d7d8582abb1b92133bcb767183289 256 Pfam PF02565 Recombination protein O C terminal 82 237 2.9E-47 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UP12_11465 f68d7d8582abb1b92133bcb767183289 256 Gene3D G3DSA:3.30.60.100 146 185 5.1E-21 T 11-10-2018 UP12_11465 f68d7d8582abb1b92133bcb767183289 256 SUPERFAMILY SSF57863 81 231 1.57E-48 T 11-10-2018 IPR037278 ARFGAP/RecO-like zinc finger UP12_11465 f68d7d8582abb1b92133bcb767183289 256 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 32.281 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 UP12_11465 f68d7d8582abb1b92133bcb767183289 256 Gene3D G3DSA:2.40.50.140 3 77 1.6E-15 T 11-10-2018 UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 Gene3D G3DSA:1.10.10.10 2 149 1.6E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 7.7E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 7.7E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 7.7E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 SUPERFAMILY SSF46785 13 142 1.5E-32 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 SMART SM00347 33 133 7.0E-35 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06480 3ed2ae3d8e84745d8e767ef6d9355a02 153 Pfam PF01047 MarR family 41 98 4.9E-20 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_11605 587cd18468398fb61958e577cd29280f 339 Gene3D G3DSA:1.20.272.10 214 338 2.1E-41 T 11-10-2018 UP12_11605 587cd18468398fb61958e577cd29280f 339 SUPERFAMILY SSF48019 217 336 2.04E-25 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UP12_11605 587cd18468398fb61958e577cd29280f 339 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 14 336 1.4E-87 T 11-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 UP12_11605 587cd18468398fb61958e577cd29280f 339 SUPERFAMILY SSF52540 3 214 7.22E-24 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11605 587cd18468398fb61958e577cd29280f 339 Gene3D G3DSA:3.40.50.300 1 143 2.3E-47 T 11-10-2018 UP12_11605 587cd18468398fb61958e577cd29280f 339 Pfam PF06144 DNA polymerase III, delta subunit 18 193 6.8E-50 T 11-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 UP12_11605 587cd18468398fb61958e577cd29280f 339 Gene3D G3DSA:1.10.8.60 144 213 4.8E-24 T 11-10-2018 UP12_18710 25d10d5319d339f3e6e2b2401329d688 326 SUPERFAMILY SSF52980 196 306 1.23E-14 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UP12_18710 25d10d5319d339f3e6e2b2401329d688 326 Pfam PF04471 Restriction endonuclease 191 302 2.0E-26 T 11-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 UP12_18710 25d10d5319d339f3e6e2b2401329d688 326 PIRSF PIRSF031853 1 326 1.9E-116 T 11-10-2018 IPR016984 Uncharacterised conserved protein UCP031853 UP12_01450 a4e9ff6243f1d3071aa11bd806637f98 467 Gene3D G3DSA:1.20.1740.10 9 464 1.1E-63 T 11-10-2018 UP12_01450 a4e9ff6243f1d3071aa11bd806637f98 467 Pfam PF00324 Amino acid permease 19 455 1.5E-117 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_01450 a4e9ff6243f1d3071aa11bd806637f98 467 PIRSF PIRSF006060 1 466 4.2E-80 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_01450 a4e9ff6243f1d3071aa11bd806637f98 467 ProSitePatterns PS00218 Amino acid permeases signature. 44 75 - T 11-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 UP12_17950 e2ea53eb5987a5b61fd33f00da069bfe 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 328 9.0E-45 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 204 241 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 Gene3D G3DSA:3.90.1150.10 13 366 9.2E-140 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 376 8.0E-156 T 11-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 SUPERFAMILY SSF53383 2 376 1.38E-127 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 Pfam PF00202 Aminotransferase class-III 12 376 3.5E-128 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 3 379 69.905 T 11-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 PIRSF PIRSF000521 6 112 4.1E-8 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 PIRSF PIRSF000521 106 147 0.084 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 PIRSF PIRSF000521 154 379 2.6E-40 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05580 f7a4e1a74052b3db96988689aa8da094 383 Gene3D G3DSA:3.40.640.10 47 286 9.2E-140 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 SUPERFAMILY SSF50249 562 662 2.94E-32 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 524 5.1E-187 T 11-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Gene3D G3DSA:1.10.730.10 352 521 2.9E-53 T 11-10-2018 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Gene3D G3DSA:2.170.220.10 119 239 8.2E-154 T 11-10-2018 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Gene3D G3DSA:3.40.50.620 8 345 8.2E-154 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Pfam PF08264 Anticodon-binding domain of tRNA 399 537 1.2E-8 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Pfam PF09334 tRNA synthetases class I (M) 8 374 6.1E-121 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Hamap MF_01228 Methionine--tRNA ligase [metG]. 4 523 52.079 T 11-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Gene3D G3DSA:2.40.50.140 554 663 1.1E-34 T 11-10-2018 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 SUPERFAMILY SSF47323 364 576 2.43E-46 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 26 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 362 373 5.6E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 5.6E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 5.6E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 5.6E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 270 285 5.6E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 PRINTS PR01041 Methionyl-tRNA synthetase signature 237 248 5.6E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 534 662 7.3E-44 T 11-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 SUPERFAMILY SSF52374 5 361 6.44E-115 T 11-10-2018 UP12_00255 b2bd41bb9e6fbe63b12b8e168870243b 663 Pfam PF01588 Putative tRNA binding domain 569 661 9.1E-27 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 28 392 1.0E-130 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 21 424 38.12 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 109 135 2.0E-31 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 137 156 2.0E-31 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 212 235 2.0E-31 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 314 333 2.0E-31 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 PRINTS PR00447 Natural resistance-associated macrophage protein signature 162 183 2.0E-31 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_02420 8fd11c876321bafd376d7ac3b20254ae 425 Pfam PF01566 Natural resistance-associated macrophage protein 50 398 7.2E-118 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_19050 a2cdc58ec09c5a684b52ad03b3c7d475 164 Pfam PF08281 Sigma-70, region 4 103 155 8.4E-12 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_19050 a2cdc58ec09c5a684b52ad03b3c7d475 164 SUPERFAMILY SSF88659 100 159 2.8E-14 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_19050 a2cdc58ec09c5a684b52ad03b3c7d475 164 Gene3D G3DSA:1.10.1740.10 2 82 6.4E-21 T 11-10-2018 UP12_19050 a2cdc58ec09c5a684b52ad03b3c7d475 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 159 2.2E-25 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_19050 a2cdc58ec09c5a684b52ad03b3c7d475 164 Gene3D G3DSA:1.10.10.10 97 161 2.0E-17 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_19050 a2cdc58ec09c5a684b52ad03b3c7d475 164 SUPERFAMILY SSF88946 8 93 7.85E-20 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_19050 a2cdc58ec09c5a684b52ad03b3c7d475 164 Pfam PF04542 Sigma-70 region 2 15 80 9.5E-14 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 Gene3D G3DSA:1.20.58.1950 223 273 1.3E-9 T 11-10-2018 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 ProSitePatterns PS00654 PRD domain signature. 95 107 - T 11-10-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 SUPERFAMILY SSF63520 169 272 1.1E-28 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 SMART SM01061 1 59 3.5E-21 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 Gene3D G3DSA:1.20.890.100 164 218 8.2E-19 T 11-10-2018 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 SUPERFAMILY SSF63520 51 163 8.11E-31 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 SUPERFAMILY SSF50151 2 53 7.72E-16 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 Gene3D G3DSA:2.30.24.10 1 55 3.9E-19 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 Gene3D G3DSA:1.10.1790.10 62 163 1.4E-33 T 11-10-2018 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 Pfam PF00874 PRD domain 178 270 1.9E-23 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 Pfam PF00874 PRD domain 73 159 1.7E-24 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_17760 03748ac3e20c86e70cc4c8baabb5a2e7 277 Pfam PF03123 CAT RNA binding domain 2 55 1.6E-17 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 Pfam PF08402 TOBE domain 281 356 5.2E-7 T 11-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 Pfam PF00005 ABC transporter 21 162 1.0E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 Gene3D G3DSA:2.40.50.100 240 361 2.7E-34 T 11-10-2018 UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 SUPERFAMILY SSF52540 6 243 1.73E-84 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 SUPERFAMILY SSF50331 237 364 7.29E-30 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 SMART SM00382 29 212 1.6E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 Gene3D G3DSA:3.40.50.300 1 239 2.4E-73 T 11-10-2018 UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_04965 fee12b48dd8c0bf94c9d75d07e56acb4 368 Gene3D G3DSA:2.40.50.140 284 349 2.7E-34 T 11-10-2018 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 Pfam PF00543 Nitrogen regulatory protein P-II 7 108 2.7E-31 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 Gene3D G3DSA:3.30.70.120 1 115 3.1E-42 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 ProSitePatterns PS00638 P-II protein C-terminal region signature. 86 99 - T 11-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 PRINTS PR00340 P-II protein signature 55 78 4.8E-22 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 PRINTS PR00340 P-II protein signature 26 44 4.8E-22 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 PRINTS PR00340 P-II protein signature 5 20 4.8E-22 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 PRINTS PR00340 P-II protein signature 86 106 4.8E-22 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 SMART SM00938 7 108 3.3E-36 T 11-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 UP12_17060 707f9d309c48fa2bb7bb170d0ad19214 115 SUPERFAMILY SSF54913 4 115 1.4E-32 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Pfam PF00175 Oxidoreductase NAD-binding domain 901 1009 1.1E-12 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Gene3D G3DSA:1.20.990.10 706 826 2.2E-68 T 11-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 11-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PIRSF PIRSF000209 1 1047 0.0 T 11-10-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Gene3D G3DSA:2.40.30.10 671 878 2.2E-68 T 11-10-2018 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 SUPERFAMILY SSF52218 481 634 1.73E-40 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Pfam PF00067 Cytochrome P450 16 449 2.1E-85 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Gene3D G3DSA:3.40.50.360 482 632 8.2E-43 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 SUPERFAMILY SSF52343 888 1046 1.19E-44 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00369 Flavodoxin signature 588 607 5.5E-10 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00369 Flavodoxin signature 563 573 5.5E-10 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00369 Flavodoxin signature 485 498 5.5E-10 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 SUPERFAMILY SSF63380 658 884 2.88E-64 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Gene3D G3DSA:3.40.50.80 889 1047 5.1E-53 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 972 988 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 863 872 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 942 953 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 696 706 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 929 938 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 828 835 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 900 919 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 995 1003 2.1E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Pfam PF00258 Flavodoxin 486 619 4.6E-29 T 11-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 SUPERFAMILY SSF48264 5 454 1.31E-111 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Gene3D G3DSA:1.10.630.10 4 472 3.2E-167 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_08650 9c9334ba8e8cb8e1a69dab2ff5434c36 1047 Pfam PF00667 FAD binding domain 663 868 7.5E-42 T 11-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 UP12_19160 c874b0e873a58fece2afb196858a5265 628 SUPERFAMILY SSF51905 7 261 3.92E-46 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_19160 c874b0e873a58fece2afb196858a5265 628 Pfam PF13932 GidA associated domain 401 615 1.8E-79 T 11-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 UP12_19160 c874b0e873a58fece2afb196858a5265 628 Gene3D G3DSA:1.10.150.570 568 620 1.8E-23 T 11-10-2018 UP12_19160 c874b0e873a58fece2afb196858a5265 628 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.409 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 UP12_19160 c874b0e873a58fece2afb196858a5265 628 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 UP12_19160 c874b0e873a58fece2afb196858a5265 628 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 UP12_19160 c874b0e873a58fece2afb196858a5265 628 Gene3D G3DSA:1.10.10.1800 459 549 3.0E-26 T 11-10-2018 UP12_19160 c874b0e873a58fece2afb196858a5265 628 Gene3D G3DSA:3.50.50.60 296 458 1.2E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_19160 c874b0e873a58fece2afb196858a5265 628 Gene3D G3DSA:3.50.50.60 2 221 5.3E-83 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_19160 c874b0e873a58fece2afb196858a5265 628 SMART SM01228 545 616 2.5E-41 T 11-10-2018 UP12_19160 c874b0e873a58fece2afb196858a5265 628 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 2.5E-299 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 UP12_19160 c874b0e873a58fece2afb196858a5265 628 Pfam PF01134 Glucose inhibited division protein A 9 399 1.6E-170 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 313 2.2E-136 T 11-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 39.434 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 464 9.5E-195 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 Gene3D G3DSA:1.20.120.1910 306 465 5.0E-38 T 11-10-2018 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 SUPERFAMILY SSF52374 4 312 1.42E-105 T 11-10-2018 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 SMART SM00840 353 417 4.0E-17 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 SUPERFAMILY SSF47323 340 464 1.63E-36 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.6E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.6E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.6E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.6E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 Pfam PF09190 DALR domain 354 412 1.4E-16 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 UP12_00620 13626df6e8fb505a1e3abff42e54d540 466 Gene3D G3DSA:3.40.50.620 1 305 1.1E-136 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_09840 0feb98d8c98a8d5e00e1760a9b8a2567 383 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 18 179 2.0E-44 T 11-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 UP12_09840 0feb98d8c98a8d5e00e1760a9b8a2567 383 Gene3D G3DSA:3.40.50.2000 187 353 1.1E-35 T 11-10-2018 UP12_09840 0feb98d8c98a8d5e00e1760a9b8a2567 383 SUPERFAMILY SSF53756 5 367 5.5E-44 T 11-10-2018 UP12_09840 0feb98d8c98a8d5e00e1760a9b8a2567 383 Pfam PF00534 Glycosyl transferases group 1 200 351 3.1E-16 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 UP12_09840 0feb98d8c98a8d5e00e1760a9b8a2567 383 Hamap MF_01280 Processive diacylglycerol beta-glucosyltransferase [ugtP]. 1 383 53.035 T 11-10-2018 IPR023589 Processive diacylglycerol beta-glucosyltransferase GO:0047228 KEGG: 00561+2.4.1.315|MetaCyc: PWY-7817 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Gene3D G3DSA:1.10.10.10 72 150 1.6E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Gene3D G3DSA:1.10.10.10 1 62 3.1E-8 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 SUPERFAMILY SSF46785 88 151 1.45E-6 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 553 682 4.5E-12 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 SUPERFAMILY SSF52794 414 488 2.41E-11 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 SUPERFAMILY SSF63520 201 294 1.27E-20 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Pfam PF05043 Mga helix-turn-helix domain 79 160 2.5E-6 T 11-10-2018 IPR007737 Mga helix-turn-helix domain UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Gene3D G3DSA:3.40.50.2300 414 501 3.0E-13 T 11-10-2018 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 416 471 3.5E-5 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 SUPERFAMILY SSF63520 308 405 2.49E-19 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Gene3D G3DSA:3.40.930.10 533 684 6.2E-13 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Pfam PF00874 PRD domain 316 403 2.5E-20 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Pfam PF00874 PRD domain 208 294 4.9E-18 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 SUPERFAMILY SSF55804 536 683 3.14E-17 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Pfam PF08279 HTH domain 6 62 9.4E-8 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Gene3D G3DSA:1.10.1790.10 310 406 1.2E-19 T 11-10-2018 UP12_02295 0d3b6ada91da9287d9498c85f157fbaa 695 Gene3D G3DSA:1.10.1790.10 202 295 2.8E-19 T 11-10-2018 UP12_13595 b49cb4c9f85a535e5f8f1a798199233d 430 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 129 2.3E-18 T 11-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UP12_13595 b49cb4c9f85a535e5f8f1a798199233d 430 SUPERFAMILY SSF51735 3 160 2.24E-31 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13595 b49cb4c9f85a535e5f8f1a798199233d 430 SUPERFAMILY SSF55347 134 360 4.25E-29 T 11-10-2018 UP12_13595 b49cb4c9f85a535e5f8f1a798199233d 430 Gene3D G3DSA:3.40.50.720 3 130 7.5E-18 T 11-10-2018 UP12_13595 b49cb4c9f85a535e5f8f1a798199233d 430 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 270 6.8E-26 T 11-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 Pfam PF00491 Arginase family 6 298 3.4E-83 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 ProSitePatterns PS01053 Arginase family signature. 228 249 - T 11-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 PIRSF PIRSF036979 2 301 2.0E-39 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 PRINTS PR00116 Arginase signature 176 194 4.1E-44 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 PRINTS PR00116 Arginase signature 225 254 4.1E-44 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 PRINTS PR00116 Arginase signature 99 114 4.1E-44 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 PRINTS PR00116 Arginase signature 260 274 4.1E-44 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 PRINTS PR00116 Arginase signature 122 149 4.1E-44 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 Gene3D G3DSA:3.40.800.10 4 303 7.5E-119 T 11-10-2018 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 TIGRFAM TIGR01229 rocF_arginase: arginase 9 303 6.6E-106 T 11-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 UP12_01050 d3b425220ba1559cb6fb102897018df6 303 SUPERFAMILY SSF52768 6 300 2.7E-95 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 SUPERFAMILY SSF46785 9 142 2.1E-32 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 SMART SM00347 29 129 7.5E-27 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 Pfam PF01047 MarR family 36 93 9.9E-17 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 Gene3D G3DSA:1.10.10.10 1 141 1.8E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.9E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.9E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_06600 6a3e4bf4a6629a1c10b8862c4deec6cf 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.9E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09535 384a3b9e5c880fab86c314701d1870d5 638 Pfam PF00092 von Willebrand factor type A domain 447 623 3.4E-9 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_09535 384a3b9e5c880fab86c314701d1870d5 638 SMART SM00327 442 632 1.2E-19 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_09535 384a3b9e5c880fab86c314701d1870d5 638 Gene3D G3DSA:3.40.50.410 443 630 9.4E-12 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_09535 384a3b9e5c880fab86c314701d1870d5 638 SUPERFAMILY SSF53300 446 630 4.6E-17 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 Gene3D G3DSA:2.40.240.60 356 428 5.7E-20 T 11-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 4.3E-12 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 48.847 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 SUPERFAMILY SSF52540 160 332 1.9E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 Gene3D G3DSA:2.70.210.12 1 157 3.9E-62 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 11-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 SUPERFAMILY SSF82051 1 157 4.32E-56 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 Pfam PF01018 GTP1/OBG 3 157 3.9E-61 T 11-10-2018 IPR006169 GTP1/OBG domain UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 1.0E-25 T 11-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 426 1.1E-26 T 11-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 2.9E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 2.9E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 2.9E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 2.9E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 PIRSF PIRSF002401 1 376 1.5E-145 T 11-10-2018 IPR035101 GTP-binding protein, Obg-type UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 4.6E-146 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 1.0E-23 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 Gene3D G3DSA:3.40.50.300 158 341 2.9E-62 T 11-10-2018 UP12_12230 7f226c9e703b8340fbed0ded8720863a 428 SUPERFAMILY SSF102741 356 428 3.27E-24 T 11-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 Gene3D G3DSA:3.40.50.720 1 241 3.6E-70 T 11-10-2018 UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 SUPERFAMILY SSF51735 3 241 1.42E-70 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 240 9.4E-52 T 11-10-2018 UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.9E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 3.9E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.9E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.9E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.9E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_08265 1e4e0db7c3a0c6299d60c69b88df2290 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.9E-36 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10110 a6405a32b095df98e16e25761fcd5063 255 PIRSF PIRSF036636 1 255 6.7E-148 T 11-10-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 UP12_10110 a6405a32b095df98e16e25761fcd5063 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 71 158 2.0E-8 T 11-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 UP12_10110 a6405a32b095df98e16e25761fcd5063 255 SUPERFAMILY SSF81648 21 156 1.14E-28 T 11-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 UP12_10110 a6405a32b095df98e16e25761fcd5063 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 184 249 1.0E-13 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_10110 a6405a32b095df98e16e25761fcd5063 255 Gene3D G3DSA:1.20.810.10 13 168 7.2E-24 T 11-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 UP12_10110 a6405a32b095df98e16e25761fcd5063 255 Gene3D G3DSA:1.10.760.10 181 253 7.3E-17 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UP12_10110 a6405a32b095df98e16e25761fcd5063 255 SUPERFAMILY SSF46626 136 251 3.93E-13 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UP12_04065 a09d380f780d9aaa73d81c4562a3fe42 319 Pfam PF01544 CorA-like Mg2+ transporter protein 28 310 6.9E-78 T 11-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 UP12_04065 a09d380f780d9aaa73d81c4562a3fe42 319 Gene3D G3DSA:1.20.58.340 125 237 3.6E-29 T 11-10-2018 UP12_04065 a09d380f780d9aaa73d81c4562a3fe42 319 Gene3D G3DSA:1.20.58.340 239 315 6.9E-32 T 11-10-2018 UP12_04065 a09d380f780d9aaa73d81c4562a3fe42 319 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 17 315 2.1E-102 T 11-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 UP12_04065 a09d380f780d9aaa73d81c4562a3fe42 319 Gene3D G3DSA:3.30.460.20 4 124 1.5E-31 T 11-10-2018 UP12_04065 a09d380f780d9aaa73d81c4562a3fe42 319 SUPERFAMILY SSF144083 250 312 1.44E-21 T 11-10-2018 UP12_04065 a09d380f780d9aaa73d81c4562a3fe42 319 SUPERFAMILY SSF143865 12 249 1.16E-63 T 11-10-2018 UP12_05050 ca38286cec7a670d0901f32b68c4666d 314 Hamap MF_01427 3'-5' exoribonuclease YhaM [yhaM]. 1 313 63.531 T 11-10-2018 IPR020873 3'-5' exoribonuclease YhaM GO:0000175 UP12_05050 ca38286cec7a670d0901f32b68c4666d 314 Gene3D G3DSA:2.40.50.140 22 100 3.2E-8 T 11-10-2018 UP12_05050 ca38286cec7a670d0901f32b68c4666d 314 Pfam PF01966 HD domain 161 278 1.5E-11 T 11-10-2018 IPR006674 HD domain UP12_05050 ca38286cec7a670d0901f32b68c4666d 314 SUPERFAMILY SSF109604 146 280 1.22E-15 T 11-10-2018 UP12_05050 ca38286cec7a670d0901f32b68c4666d 314 SMART SM00471 156 288 8.0E-6 T 11-10-2018 IPR003607 HD/PDEase domain UP12_05050 ca38286cec7a670d0901f32b68c4666d 314 Gene3D G3DSA:1.10.3210.10 122 296 4.7E-13 T 11-10-2018 UP12_18690 6030478262f5ff3c2d65e5a35b06cf51 397 Gene3D G3DSA:1.20.1250.20 5 195 4.6E-26 T 11-10-2018 UP12_18690 6030478262f5ff3c2d65e5a35b06cf51 397 Pfam PF07690 Major Facilitator Superfamily 13 298 4.4E-29 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_18690 6030478262f5ff3c2d65e5a35b06cf51 397 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_18690 6030478262f5ff3c2d65e5a35b06cf51 397 Gene3D G3DSA:1.20.1250.20 203 393 1.0E-15 T 11-10-2018 UP12_18690 6030478262f5ff3c2d65e5a35b06cf51 397 SUPERFAMILY SSF103473 7 392 2.62E-49 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Hamap MF_01263 CCA-adding enzyme [cca]. 2 394 38.254 T 11-10-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 169 228 1.5E-13 T 11-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Pfam PF01743 Poly A polymerase head domain 22 141 3.7E-38 T 11-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 SUPERFAMILY SSF81891 140 392 1.18E-47 T 11-10-2018 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Gene3D G3DSA:1.10.246.80 338 400 1.1E-17 T 11-10-2018 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 248 389 7.6E-31 T 11-10-2018 IPR032810 CCA-adding enzyme, C-terminal UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Gene3D G3DSA:3.30.460.10 2 144 2.4E-53 T 11-10-2018 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 SUPERFAMILY SSF81301 5 139 1.74E-44 T 11-10-2018 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Gene3D G3DSA:1.10.110.30 145 238 5.2E-28 T 11-10-2018 UP12_10065 6826b2c7fc69cd56630e73831417e223 400 Gene3D G3DSA:1.20.58.560 241 337 1.3E-7 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Gene3D G3DSA:3.50.50.60 110 244 3.5E-88 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 SUPERFAMILY SSF56014 626 786 4.06E-47 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PIRSF PIRSF037149 1 806 0.0 T 11-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 786 0.0 T 11-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Gene3D G3DSA:3.30.390.30 316 399 1.1E-8 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 555 617 4.8E-13 T 11-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 2.3E-11 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 2.3E-11 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 2.3E-11 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.3E-11 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Pfam PF04324 BFD-like [2Fe-2S] binding domain 415 463 4.7E-16 T 11-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Pfam PF04324 BFD-like [2Fe-2S] binding domain 479 529 1.2E-11 T 11-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 625 759 4.6E-26 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Gene3D G3DSA:3.50.50.60 7 280 3.5E-88 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 SUPERFAMILY SSF55124 490 617 2.33E-24 T 11-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 281 7.4E-59 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00397 Sirohaem Fe-binding site signature 629 647 1.1E-6 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00397 Sirohaem Fe-binding site signature 672 690 1.1E-6 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 9.2E-22 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 9.2E-22 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 9.2E-22 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.2E-22 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 9.2E-22 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 SUPERFAMILY SSF51905 3 193 6.15E-41 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 SUPERFAMILY SSF51905 147 305 3.89E-28 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Gene3D G3DSA:1.10.10.1100 415 469 1.2E-11 T 11-10-2018 UP12_09285 c6f9faafa3f6fc72678610ec224dadb7 807 Gene3D G3DSA:3.30.413.10 624 796 5.9E-37 T 11-10-2018 UP12_17235 9feedb3508ace7d5a8a6d02860c3ff23 149 PIRSF PIRSF005384 1 148 2.7E-57 T 11-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UP12_17235 9feedb3508ace7d5a8a6d02860c3ff23 149 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 4.2E-62 T 11-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UP12_17235 9feedb3508ace7d5a8a6d02860c3ff23 149 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 4.4E-50 T 11-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 UP12_17235 9feedb3508ace7d5a8a6d02860c3ff23 149 Pfam PF02502 Ribose/Galactose Isomerase 3 141 1.5E-54 T 11-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UP12_17235 9feedb3508ace7d5a8a6d02860c3ff23 149 Gene3D G3DSA:3.40.1400.10 1 148 2.2E-58 T 11-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UP12_17235 9feedb3508ace7d5a8a6d02860c3ff23 149 SUPERFAMILY SSF89623 1 148 4.45E-57 T 11-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 SMART SM00345 8 67 1.0E-19 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 Gene3D G3DSA:3.40.50.2300 187 353 2.8E-77 T 11-10-2018 UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 Pfam PF13377 Periplasmic binding protein-like domain 196 357 1.9E-27 T 11-10-2018 UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 Gene3D G3DSA:3.40.50.2300 84 350 2.8E-77 T 11-10-2018 UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 Gene3D G3DSA:1.10.10.10 1 74 8.0E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 SUPERFAMILY SSF53822 82 360 1.24E-58 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 6.0E-19 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 SUPERFAMILY SSF46785 3 71 9.48E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 8.9E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_11765 f13579bc7e14e562002b7f6788ef9152 366 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 8.9E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Gene3D G3DSA:3.30.565.10 463 609 1.7E-41 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 555 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 559 569 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 594 607 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 588 1.1E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SUPERFAMILY SSF55874 461 607 1.09E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Pfam PF00512 His Kinase A (phospho-acceptor) domain 400 460 6.0E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Gene3D G3DSA:3.30.450.20 11 117 1.6E-16 T 11-10-2018 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 504 607 6.9E-23 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SUPERFAMILY SSF55785 19 94 5.98E-8 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Pfam PF00989 PAS fold 149 247 3.5E-13 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Pfam PF00989 PAS fold 270 380 4.0E-11 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SUPERFAMILY SSF55785 165 266 1.32E-15 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SUPERFAMILY SSF55785 255 381 1.77E-10 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Gene3D G3DSA:3.30.450.20 265 385 1.8E-10 T 11-10-2018 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Gene3D G3DSA:3.30.450.20 159 264 1.7E-13 T 11-10-2018 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 Gene3D G3DSA:1.10.287.130 386 461 5.4E-18 T 11-10-2018 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SMART SM00388 398 461 1.9E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SUPERFAMILY SSF47384 394 459 6.08E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SMART SM00387 504 609 1.3E-32 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SMART SM00091 5 71 1.2 T 11-10-2018 IPR000014 PAS domain UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SMART SM00091 270 336 3.0E-4 T 11-10-2018 IPR000014 PAS domain UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 SMART SM00091 146 212 1.7E-7 T 11-10-2018 IPR000014 PAS domain UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 164 262 4.7E-15 T 11-10-2018 IPR000014 PAS domain UP12_06750 809a39d60af00e53d5286c9ac0409c9e 609 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 267 388 1.5E-8 T 11-10-2018 IPR000014 PAS domain UP12_16590 c54a25e0eba18c508974cbc0fc8f4dde 375 Gene3D G3DSA:3.40.50.300 23 197 1.2E-16 T 11-10-2018 UP12_16590 c54a25e0eba18c508974cbc0fc8f4dde 375 SUPERFAMILY SSF52540 46 346 6.24E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16590 c54a25e0eba18c508974cbc0fc8f4dde 375 SMART SM00487 29 211 8.4E-19 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_16590 c54a25e0eba18c508974cbc0fc8f4dde 375 Gene3D G3DSA:3.40.50.300 212 349 3.1E-28 T 11-10-2018 UP12_16590 c54a25e0eba18c508974cbc0fc8f4dde 375 SMART SM00490 255 336 2.3E-12 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_16590 c54a25e0eba18c508974cbc0fc8f4dde 375 Pfam PF00271 Helicase conserved C-terminal domain 237 335 4.1E-13 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_16590 c54a25e0eba18c508974cbc0fc8f4dde 375 Pfam PF04851 Type III restriction enzyme, res subunit 32 180 8.2E-10 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UP12_01355 609c71c5ffabb65395a59944d4c74d37 360 Gene3D G3DSA:1.20.1090.10 156 360 4.8E-54 T 11-10-2018 UP12_01355 609c71c5ffabb65395a59944d4c74d37 360 SUPERFAMILY SSF56796 11 349 5.63E-54 T 11-10-2018 UP12_01355 609c71c5ffabb65395a59944d4c74d37 360 PIRSF PIRSF000112 1 357 1.5E-107 T 11-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 UP12_01355 609c71c5ffabb65395a59944d4c74d37 360 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 329 6.4E-43 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 UP12_01355 609c71c5ffabb65395a59944d4c74d37 360 Gene3D G3DSA:3.40.50.1970 8 153 5.6E-22 T 11-10-2018 UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 246 266 3.7E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 229 3.7E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 181 3.7E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 210 3.7E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 130 3.7E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 44 61 3.7E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 52 281 8.7E-59 T 11-10-2018 UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 Gene3D G3DSA:3.40.50.720 2 283 3.8E-86 T 11-10-2018 UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 178 206 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 SUPERFAMILY SSF51735 42 284 1.31E-81 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 179 3.7E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 119 130 3.7E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05230 2868f5d0ff10b9c8a8c5f418fa27a72b 286 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 191 210 3.7E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_00135 36430b33aeebf16342150db3230eaf75 570 Gene3D G3DSA:1.10.8.60 8 235 1.7E-105 T 11-10-2018 UP12_00135 36430b33aeebf16342150db3230eaf75 570 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 3.5E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_00135 36430b33aeebf16342150db3230eaf75 570 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 3.5E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_00135 36430b33aeebf16342150db3230eaf75 570 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 1.8E-144 T 11-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 UP12_00135 36430b33aeebf16342150db3230eaf75 570 Gene3D G3DSA:1.20.272.10 242 360 9.7E-9 T 11-10-2018 UP12_00135 36430b33aeebf16342150db3230eaf75 570 Gene3D G3DSA:3.40.50.300 13 177 1.7E-105 T 11-10-2018 UP12_00135 36430b33aeebf16342150db3230eaf75 570 SMART SM00382 37 179 1.2E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00135 36430b33aeebf16342150db3230eaf75 570 SUPERFAMILY SSF48019 244 359 1.11E-25 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UP12_00135 36430b33aeebf16342150db3230eaf75 570 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 240 362 2.0E-12 T 11-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 UP12_00135 36430b33aeebf16342150db3230eaf75 570 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.0E-45 T 11-10-2018 UP12_00135 36430b33aeebf16342150db3230eaf75 570 SUPERFAMILY SSF52540 31 222 5.04E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00380 b3c2c863da68632402c114ad83fbbcb0 132 Pfam PF00575 S1 RNA binding domain 4 74 1.5E-21 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_00380 b3c2c863da68632402c114ad83fbbcb0 132 SMART SM00316 4 74 9.9E-26 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_00380 b3c2c863da68632402c114ad83fbbcb0 132 SUPERFAMILY SSF50249 4 83 9.61E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_00380 b3c2c863da68632402c114ad83fbbcb0 132 Gene3D G3DSA:2.40.50.140 1 85 2.8E-29 T 11-10-2018 UP12_13200 ec82b828755add43a0ddc214bc7615f8 324 SUPERFAMILY SSF53335 36 309 8.29E-43 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_13200 ec82b828755add43a0ddc214bc7615f8 324 Gene3D G3DSA:3.40.50.150 80 320 1.2E-50 T 11-10-2018 UP12_13200 ec82b828755add43a0ddc214bc7615f8 324 Pfam PF02384 N-6 DNA Methylase 97 304 8.4E-13 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UP12_13200 ec82b828755add43a0ddc214bc7615f8 324 PIRSF PIRSF026567 1 321 1.1E-122 T 11-10-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted UP12_13200 ec82b828755add43a0ddc214bc7615f8 324 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 209 233 5.6E-8 T 11-10-2018 UP12_13200 ec82b828755add43a0ddc214bc7615f8 324 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 113 127 5.6E-8 T 11-10-2018 UP12_13200 ec82b828755add43a0ddc214bc7615f8 324 Gene3D G3DSA:1.10.150.470 1 77 2.7E-14 T 11-10-2018 UP12_13425 b32d30ee6b4ba1b8b4c581f4bf842293 107 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 6 104 3.7E-35 T 11-10-2018 IPR022551 Protein of unknown function DUF2847 UP12_13425 b32d30ee6b4ba1b8b4c581f4bf842293 107 Gene3D G3DSA:3.40.30.10 2 106 4.1E-35 T 11-10-2018 UP12_13425 b32d30ee6b4ba1b8b4c581f4bf842293 107 SUPERFAMILY SSF52833 4 103 1.66E-8 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_13425 b32d30ee6b4ba1b8b4c581f4bf842293 107 Pfam PF11009 Protein of unknown function (DUF2847) 6 103 3.1E-34 T 11-10-2018 IPR022551 Protein of unknown function DUF2847 UP12_02150 95fe533db0028cfcc6f6306fbda6bf5a 299 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.3E-14 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02150 95fe533db0028cfcc6f6306fbda6bf5a 299 Gene3D G3DSA:1.10.357.10 10 219 3.7E-22 T 11-10-2018 UP12_02150 95fe533db0028cfcc6f6306fbda6bf5a 299 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.7E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02150 95fe533db0028cfcc6f6306fbda6bf5a 299 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.7E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02150 95fe533db0028cfcc6f6306fbda6bf5a 299 SUPERFAMILY SSF46689 12 75 2.62E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 443 3.7E-186 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 SUPERFAMILY SSF55957 357 446 1.57E-27 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Gene3D G3DSA:3.40.120.10 3 155 2.0E-58 T 11-10-2018 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Gene3D G3DSA:3.40.120.10 174 362 4.3E-72 T 11-10-2018 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 1.0E-15 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 2.3E-43 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.354 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 SUPERFAMILY SSF53738 257 366 1.06E-33 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 368 3.4E-36 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Gene3D G3DSA:3.40.120.10 256 339 4.3E-72 T 11-10-2018 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 SUPERFAMILY SSF53738 3 180 3.73E-46 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Gene3D G3DSA:3.30.310.50 370 448 6.6E-30 T 11-10-2018 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 SUPERFAMILY SSF53738 158 256 1.53E-25 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 441 3.5E-19 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 8.2E-12 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 8.2E-12 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_01075 3a8f8cea773eaa8cf925af3f39bd211f 448 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 8.2E-12 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 ProSitePatterns PS00480 Citrate synthase signature. 259 272 - T 11-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 PRINTS PR00143 Citrate synthase signature 177 192 2.0E-32 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 PRINTS PR00143 Citrate synthase signature 310 326 2.0E-32 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 PRINTS PR00143 Citrate synthase signature 330 344 2.0E-32 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 PRINTS PR00143 Citrate synthase signature 128 141 2.0E-32 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 PRINTS PR00143 Citrate synthase signature 199 227 2.0E-32 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 PRINTS PR00143 Citrate synthase signature 252 272 2.0E-32 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 Pfam PF00285 Citrate synthase, C-terminal domain 10 360 1.4E-109 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 PIRSF PIRSF001369 1 377 4.6E-129 T 11-10-2018 IPR024176 Citrate synthase, bacterial-type UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 SUPERFAMILY SSF48256 5 367 3.27E-115 T 11-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 Gene3D G3DSA:1.10.580.10 32 357 4.9E-108 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UP12_09460 0b37469daebff8c242fe4559b8214c9e 380 Gene3D G3DSA:1.10.230.10 225 324 4.9E-108 T 11-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 491 501 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 SUPERFAMILY SSF52743 449 725 1.96E-75 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 Gene3D G3DSA:3.40.50.200 406 693 3.6E-76 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 Gene3D G3DSA:2.60.40.10 806 883 1.2E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 Gene3D G3DSA:2.60.40.10 726 798 6.2E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 642 652 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 PRINTS PR00723 Subtilisin serine protease family (S8) signature 641 657 2.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 PRINTS PR00723 Subtilisin serine protease family (S8) signature 487 500 2.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 PRINTS PR00723 Subtilisin serine protease family (S8) signature 447 466 2.9E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_01435 37f1d5b9c8f112df12cba77632ad4a99 889 Pfam PF00082 Subtilase family 448 680 3.7E-43 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 PIRSF PIRSF011572 1 257 1.9E-122 T 11-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 Pfam PF08222 CodY helix-turn-helix domain 198 257 5.4E-37 T 11-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 SUPERFAMILY SSF46785 167 256 4.85E-42 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 Pfam PF06018 CodY GAF-like domain 3 178 1.6E-80 T 11-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 Gene3D G3DSA:1.10.10.10 160 259 9.8E-48 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 147.756 T 11-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 Gene3D G3DSA:3.30.450.40 1 159 2.7E-71 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_07875 6ee098954bbaf9a0a88a6789d96e7a43 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 1.5E-128 T 11-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 UP12_12325 163756c1486b2e0626698c68457d28bd 343 Gene3D G3DSA:3.90.1200.10 94 317 1.5E-18 T 11-10-2018 UP12_12325 163756c1486b2e0626698c68457d28bd 343 TIGRFAM TIGR02904 spore_ysxE: spore coat protein YsxE 4 310 1.2E-107 T 11-10-2018 IPR014253 Spore coat protein YsxE UP12_12325 163756c1486b2e0626698c68457d28bd 343 Gene3D G3DSA:3.30.200.20 2 91 1.9E-14 T 11-10-2018 UP12_12325 163756c1486b2e0626698c68457d28bd 343 SUPERFAMILY SSF56112 2 291 4.59E-14 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_14730 a815f54efeb6033775b87216f2f38f12 663 Gene3D G3DSA:1.10.287.950 354 661 1.3E-70 T 11-10-2018 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 SMART SM00283 386 661 6.3E-91 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 SUPERFAMILY SSF103190 98 193 1.26E-12 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_14730 a815f54efeb6033775b87216f2f38f12 663 SUPERFAMILY SSF58104 325 661 3.92E-72 T 11-10-2018 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 Pfam PF00672 HAMP domain 305 353 2.4E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 Gene3D G3DSA:3.30.450.20 64 268 2.0E-39 T 11-10-2018 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 SMART SM00319 33 153 4.4E-7 T 11-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 434 614 1.7E-52 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 Pfam PF02743 Cache domain 45 266 8.2E-29 T 11-10-2018 IPR033479 Double Cache domain 1 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 Gene3D G3DSA:3.30.450.20 72 185 2.0E-39 T 11-10-2018 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 SMART SM00304 305 357 3.6E-11 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14730 a815f54efeb6033775b87216f2f38f12 663 SMART SM00304 371 431 17.0 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_03440 341e80da49b94a070d8b375ff2ed9ca3 104 SUPERFAMILY SSF48295 3 94 2.88E-32 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 UP12_03440 341e80da49b94a070d8b375ff2ed9ca3 104 PIRSF PIRSF012508 1 100 4.5E-48 T 11-10-2018 IPR013368 TrpR homologue YerC/YecD UP12_03440 341e80da49b94a070d8b375ff2ed9ca3 104 Pfam PF01371 Trp repressor protein 10 93 1.7E-34 T 11-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 UP12_03440 341e80da49b94a070d8b375ff2ed9ca3 104 Gene3D G3DSA:1.10.1270.10 2 104 3.0E-39 T 11-10-2018 IPR038116 TrpR-like superfamily UP12_03440 341e80da49b94a070d8b375ff2ed9ca3 104 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 6.0E-50 T 11-10-2018 IPR013368 TrpR homologue YerC/YecD UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 SUPERFAMILY SSF47005 95 138 7.19E-11 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 Gene3D G3DSA:4.10.320.10 98 137 6.6E-15 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 Gene3D G3DSA:2.40.50.100 2 97 5.5E-26 T 11-10-2018 UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 SUPERFAMILY SSF51230 1 88 2.75E-24 T 11-10-2018 IPR011053 Single hybrid motif UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 147 375 1.7E-77 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 Pfam PF00364 Biotin-requiring enzyme 4 76 1.2E-17 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 Gene3D G3DSA:3.30.559.10 138 373 1.3E-78 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 Pfam PF02817 e3 binding domain 101 135 1.3E-13 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UP12_02610 79de311fe2b6a1ea583c3ed80298a6bd 376 SUPERFAMILY SSF52777 151 376 1.33E-74 T 11-10-2018 UP12_12280 503cd7c4e3eed281b1181cca3fbc35a3 299 Gene3D G3DSA:2.40.10.340 113 189 1.5E-18 T 11-10-2018 UP12_12280 503cd7c4e3eed281b1181cca3fbc35a3 299 Gene3D G3DSA:2.40.10.350 190 269 7.7E-25 T 11-10-2018 UP12_12280 503cd7c4e3eed281b1181cca3fbc35a3 299 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 6 290 1.1E-87 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 UP12_12280 503cd7c4e3eed281b1181cca3fbc35a3 299 PIRSF PIRSF038471 1 296 6.3E-59 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 UP12_12280 503cd7c4e3eed281b1181cca3fbc35a3 299 Pfam PF04085 rod shape-determining protein MreC 123 281 1.5E-41 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 UP12_04225 e446e03d233fef32d84587f7a45c9546 248 Pfam PF13490 Putative zinc-finger 8 34 7.5E-6 T 11-10-2018 IPR027383 Putative zinc-finger UP12_04225 e446e03d233fef32d84587f7a45c9546 248 Gene3D G3DSA:1.10.10.1320 4 101 2.1E-8 T 11-10-2018 UP12_04225 e446e03d233fef32d84587f7a45c9546 248 Pfam PF10099 Anti-sigma-K factor rskA 57 245 4.9E-24 T 11-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 Gene3D G3DSA:3.40.50.1220 198 376 5.0E-53 T 11-10-2018 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 3 569 36.896 T 11-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 Gene3D G3DSA:3.40.50.970 378 579 1.2E-69 T 11-10-2018 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 Gene3D G3DSA:3.40.50.970 1 173 1.1E-68 T 11-10-2018 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 SUPERFAMILY SSF52467 166 369 3.93E-11 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 419 551 9.3E-10 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 10 444 2.7E-151 T 11-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 14 175 1.0E-35 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 SUPERFAMILY SSF52518 384 566 6.41E-31 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 Pfam PF16582 Middle domain of thiamine pyrophosphate 218 401 8.9E-17 T 11-10-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 PIRSF PIRSF004983 2 576 9.5E-198 T 11-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 UP12_13910 22613c2f9f91f9b617b1e41d849611db 580 SUPERFAMILY SSF52518 6 179 1.37E-34 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_09570 95d834a0f80775f15933f891c13b5aeb 116 SUPERFAMILY SSF89442 1 115 1.31E-52 T 11-10-2018 IPR036492 Hypothetical protein YojF superfamily UP12_09570 95d834a0f80775f15933f891c13b5aeb 116 Gene3D G3DSA:2.70.180.10 1 116 1.0E-50 T 11-10-2018 IPR036492 Hypothetical protein YojF superfamily UP12_09570 95d834a0f80775f15933f891c13b5aeb 116 Pfam PF08830 Protein of unknown function (DUF1806) 3 114 2.7E-51 T 11-10-2018 IPR014934 Protein of unknown function DUF1806 UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 Gene3D G3DSA:3.30.70.270 357 523 1.3E-50 T 11-10-2018 UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 SUPERFAMILY SSF55785 247 358 7.23E-7 T 11-10-2018 IPR035965 PAS domain superfamily UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 Pfam PF16927 N-terminal 7TM region of histidine kinase 12 235 8.4E-50 T 11-10-2018 IPR031621 Histidine kinase, N-terminal 7TM region UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 356 517 5.1E-45 T 11-10-2018 IPR000160 GGDEF domain UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 SUPERFAMILY SSF55073 365 516 2.04E-43 T 11-10-2018 IPR029787 Nucleotide cyclase UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 Gene3D G3DSA:3.30.450.20 237 356 8.4E-13 T 11-10-2018 UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 SMART SM00267 349 518 6.8E-56 T 11-10-2018 IPR000160 GGDEF domain UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 Pfam PF00990 Diguanylate cyclase, GGDEF domain 360 514 3.4E-39 T 11-10-2018 IPR000160 GGDEF domain UP12_15785 7e3c5a75dc37fc6076aaa9abbfca5d5d 530 Pfam PF13188 PAS domain 239 268 1.7E-4 T 11-10-2018 IPR000014 PAS domain UP12_02345 06413d6feaeaec3919e4d33f565c8430 310 SUPERFAMILY SSF103481 188 288 7.72E-15 T 11-10-2018 UP12_02345 06413d6feaeaec3919e4d33f565c8430 310 SUPERFAMILY SSF103481 41 142 4.45E-13 T 11-10-2018 UP12_02345 06413d6feaeaec3919e4d33f565c8430 310 Pfam PF00892 EamA-like transporter family 151 287 8.2E-21 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_02345 06413d6feaeaec3919e4d33f565c8430 310 Pfam PF00892 EamA-like transporter family 7 140 1.9E-21 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PIRSF PIRSF000530 1 388 4.8E-118 T 11-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 Gene3D G3DSA:3.30.70.890 202 360 6.6E-133 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 11-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 TIGRFAM TIGR00131 gal_kin: galactokinase 5 386 3.3E-129 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 Pfam PF00288 GHMP kinases N terminal domain 114 181 1.9E-13 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 SUPERFAMILY SSF55060 205 385 6.58E-50 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 SUPERFAMILY SSF54211 2 202 1.29E-61 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 Pfam PF10509 Galactokinase galactose-binding signature 8 57 5.0E-23 T 11-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 11-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00473 Galactokinase signature 91 102 7.1E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00473 Galactokinase signature 112 130 7.1E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00473 Galactokinase signature 26 44 7.1E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00473 Galactokinase signature 269 283 7.1E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00959 Mevalonate kinase family signature 24 48 1.0E-43 T 11-10-2018 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00959 Mevalonate kinase family signature 119 141 1.0E-43 T 11-10-2018 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00959 Mevalonate kinase family signature 162 181 1.0E-43 T 11-10-2018 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 PRINTS PR00959 Mevalonate kinase family signature 333 350 1.0E-43 T 11-10-2018 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 Pfam PF08544 GHMP kinases C terminal 293 352 7.2E-7 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 Hamap MF_00246 Galactokinase [galK]. 24 386 45.387 T 11-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17835 f9138755c5ae8c87e6b15bbf651391ac 392 Gene3D G3DSA:3.30.230.10 21 201 6.6E-133 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_18150 508eb1368aefca7a7fbe527f15eda432 107 Gene3D G3DSA:3.40.50.2300 2 107 4.2E-32 T 11-10-2018 UP12_18150 508eb1368aefca7a7fbe527f15eda432 107 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 98 9.1E-20 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_18150 508eb1368aefca7a7fbe527f15eda432 107 SUPERFAMILY SSF52794 1 105 2.88E-31 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_17330 9f45afda4d826235fe2c27170970fea7 124 Gene3D G3DSA:3.40.50.2300 1 123 2.6E-43 T 11-10-2018 UP12_17330 9f45afda4d826235fe2c27170970fea7 124 Pfam PF00072 Response regulator receiver domain 5 115 1.2E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_17330 9f45afda4d826235fe2c27170970fea7 124 SMART SM00448 3 114 2.8E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_17330 9f45afda4d826235fe2c27170970fea7 124 SUPERFAMILY SSF52172 4 119 5.83E-36 T 11-10-2018 IPR011006 CheY-like superfamily UP12_04890 474532d104c240e8071a9d5775f34944 146 Pfam PF13411 MerR HTH family regulatory protein 15 82 1.1E-16 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_04890 474532d104c240e8071a9d5775f34944 146 SUPERFAMILY SSF46955 15 119 1.65E-20 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_04890 474532d104c240e8071a9d5775f34944 146 Gene3D G3DSA:1.10.1660.10 3 132 1.6E-23 T 11-10-2018 UP12_04890 474532d104c240e8071a9d5775f34944 146 SMART SM00422 15 83 2.8E-24 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_03735 358663feaea0b283a4357cf1aa0f034c 309 Pfam PF03407 Nucleotide-diphospho-sugar transferase 36 174 1.7E-6 T 11-10-2018 IPR005069 Nucleotide-diphospho-sugar transferase UP12_03735 358663feaea0b283a4357cf1aa0f034c 309 SUPERFAMILY SSF53448 4 281 8.15E-16 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_05445 50785b8f1893d9640f1fad7c06d76c72 178 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 154 4.3E-6 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_05445 50785b8f1893d9640f1fad7c06d76c72 178 Gene3D G3DSA:2.160.10.10 76 177 9.5E-23 T 11-10-2018 UP12_05445 50785b8f1893d9640f1fad7c06d76c72 178 SUPERFAMILY SSF51161 45 175 9.56E-25 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_17340 8677056a069f2ca0eec494ded417550b 535 Pfam PF06418 CTP synthase N-terminus 3 267 3.6E-131 T 11-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UP12_17340 8677056a069f2ca0eec494ded417550b 535 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 6.0E-268 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UP12_17340 8677056a069f2ca0eec494ded417550b 535 Gene3D G3DSA:3.40.50.880 287 535 7.8E-102 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_17340 8677056a069f2ca0eec494ded417550b 535 Gene3D G3DSA:3.40.50.300 1 286 1.4E-135 T 11-10-2018 UP12_17340 8677056a069f2ca0eec494ded417550b 535 SUPERFAMILY SSF52317 289 530 6.27E-84 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_17340 8677056a069f2ca0eec494ded417550b 535 Hamap MF_01227 CTP synthase [pyrG]. 2 532 52.972 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 UP12_17340 8677056a069f2ca0eec494ded417550b 535 SUPERFAMILY SSF52540 1 269 1.37E-127 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17340 8677056a069f2ca0eec494ded417550b 535 Pfam PF00117 Glutamine amidotransferase class-I 302 525 5.3E-58 T 11-10-2018 IPR017926 Glutamine amidotransferase UP12_12370 54a5c6b0fb4e3d5b0a5f2d31ff9f847d 195 SUPERFAMILY SSF52540 16 193 1.27E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12370 54a5c6b0fb4e3d5b0a5f2d31ff9f847d 195 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 8 189 4.0E-70 T 11-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 UP12_12370 54a5c6b0fb4e3d5b0a5f2d31ff9f847d 195 Gene3D G3DSA:3.40.50.300 1 194 2.8E-54 T 11-10-2018 UP12_12370 54a5c6b0fb4e3d5b0a5f2d31ff9f847d 195 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.643 T 11-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 UP12_12370 54a5c6b0fb4e3d5b0a5f2d31ff9f847d 195 Pfam PF01926 50S ribosome-binding GTPase 25 143 1.4E-20 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 SUPERFAMILY SSF52943 2 287 1.1E-91 T 11-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 2 287 2.3E-110 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 PRINTS PR00126 ATP synthase gamma subunit signature 165 182 2.1E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 2.1E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 2.1E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 PRINTS PR00126 ATP synthase gamma subunit signature 72 91 2.1E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 11-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 36.019 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 Pfam PF00231 ATP synthase 3 287 2.6E-99 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 Gene3D G3DSA:1.10.287.80 6 283 2.1E-103 T 11-10-2018 UP12_17185 dd8ee19ac3db68ac31b612f5e840be01 288 Gene3D G3DSA:3.40.1380.10 60 206 2.1E-103 T 11-10-2018 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Gene3D G3DSA:3.30.420.340 365 523 2.6E-62 T 11-10-2018 IPR038476 UvrC homology region 2 superfamily UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 SUPERFAMILY SSF47781 502 589 5.72E-21 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 SUPERFAMILY SSF46600 182 235 3.27E-14 T 11-10-2018 IPR036876 UVR domain superfamily UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Pfam PF01541 GIY-YIG catalytic domain 16 90 9.5E-11 T 11-10-2018 IPR000305 GIY-YIG endonuclease UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Pfam PF14520 Helix-hairpin-helix domain 539 590 2.6E-7 T 11-10-2018 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 SUPERFAMILY SSF82771 14 97 1.12E-21 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 570 5.9E-225 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 29.137 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Gene3D G3DSA:1.10.150.20 527 589 9.1E-21 T 11-10-2018 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 376 523 3.9E-57 T 11-10-2018 IPR001162 UvrC family homology region UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Pfam PF02151 UvrB/uvrC motif 199 228 2.2E-9 T 11-10-2018 IPR001943 UVR domain GO:0005515 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 Gene3D G3DSA:3.40.1440.10 1 99 5.7E-38 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UP12_12840 a922c29be77b75cf713f456cb0cccbf9 590 SMART SM00465 15 95 5.0E-25 T 11-10-2018 IPR000305 GIY-YIG endonuclease UP12_15340 1c2108cd06451fecdc7f5b1794720036 310 Pfam PF13280 WYL domain 139 306 1.1E-23 T 11-10-2018 IPR026881 WYL domain UP12_15340 1c2108cd06451fecdc7f5b1794720036 310 Gene3D G3DSA:1.10.10.10 1 64 4.6E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15340 1c2108cd06451fecdc7f5b1794720036 310 SUPERFAMILY SSF46785 1 63 7.39E-7 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_15340 1c2108cd06451fecdc7f5b1794720036 310 Pfam PF08279 HTH domain 6 61 9.6E-8 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 SUPERFAMILY SSF102114 126 363 1.44E-57 T 11-10-2018 UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 SMART SM00729 143 361 1.7E-59 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 1.1E-25 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 Gene3D G3DSA:3.80.30.20 140 374 1.9E-87 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 Pfam PF01938 TRAM domain 391 435 8.3E-6 T 11-10-2018 IPR002792 TRAM domain UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 424 7.6E-142 T 11-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 Pfam PF04055 Radical SAM superfamily 149 319 3.5E-29 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 432 1.1E-151 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 Gene3D G3DSA:3.40.50.12160 3 132 2.0E-24 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily UP12_11540 62ef5a9e6a168b47ef95b9829089eff3 452 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 1.1E-141 T 11-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 Gene3D G3DSA:3.10.400.10 3 152 1.9E-47 T 11-10-2018 UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 SUPERFAMILY SSF52374 161 371 3.13E-84 T 11-10-2018 UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 SUPERFAMILY SSF88697 4 158 3.78E-48 T 11-10-2018 IPR015947 PUA-like superfamily UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 Pfam PF14306 PUA-like domain 4 153 1.1E-50 T 11-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 Pfam PF01747 ATP-sulfurylase 161 371 7.3E-93 T 11-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 Gene3D G3DSA:3.40.50.620 161 373 2.0E-95 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_07590 66b9afc5edfe1d59f9ab45b177098ce2 378 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 20 375 50.674 T 11-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 UP12_17520 798af1d73f39ed7dba91aa4d087eb29e 161 SUPERFAMILY SSF48452 4 155 1.99E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_17520 798af1d73f39ed7dba91aa4d087eb29e 161 Pfam PF12688 Tetratrico peptide repeat 38 156 1.7E-12 T 11-10-2018 UP12_17520 798af1d73f39ed7dba91aa4d087eb29e 161 Gene3D G3DSA:1.25.40.10 46 154 1.1E-24 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_17520 798af1d73f39ed7dba91aa4d087eb29e 161 SMART SM00028 1 34 490.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_17520 798af1d73f39ed7dba91aa4d087eb29e 161 SMART SM00028 72 105 0.11 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_17520 798af1d73f39ed7dba91aa4d087eb29e 161 SMART SM00028 35 68 6.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 Gene3D G3DSA:1.10.720.10 1 48 1.1E-21 T 11-10-2018 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 416 220.909 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 TIGRFAM TIGR00767 rho: transcription termination factor Rho 5 414 1.6E-205 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 SMART SM00382 169 354 7.0E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 SUPERFAMILY SSF52540 92 370 3.34E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 SMART SM00959 8 50 9.2E-15 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 Gene3D G3DSA:2.40.50.140 50 125 9.2E-29 T 11-10-2018 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 SMART SM00357 55 120 7.8E-20 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 Pfam PF07497 Rho termination factor, RNA-binding domain 54 127 3.3E-31 T 11-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 SUPERFAMILY SSF68912 5 49 9.42E-11 T 11-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 Pfam PF07498 Rho termination factor, N-terminal domain 9 49 3.4E-15 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 Gene3D G3DSA:3.40.50.300 132 414 9.9E-123 T 11-10-2018 UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 SUPERFAMILY SSF50249 52 127 4.57E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_17305 a8c6f709dafe319fff4686f5a0f6edaf 427 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 158 362 4.3E-19 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 Pfam PF01926 50S ribosome-binding GTPase 123 213 2.5E-17 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 169 184 1.5E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 123 143 1.5E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 278 1.1E-115 T 11-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 Gene3D G3DSA:1.10.1580.10 180 272 3.5E-30 T 11-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 Gene3D G3DSA:3.40.50.300 12 179 1.5E-50 T 11-10-2018 UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 PIRSF PIRSF006230 1 282 1.2E-104 T 11-10-2018 IPR016478 GTPase, MTG1 UP12_07815 664d7d5ba282bfa5afbf9b8a1d44fed7 282 SUPERFAMILY SSF52540 9 204 3.07E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00700 1ddfacb80886eb17d259a72e80f6b99f 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.8E-66 T 11-10-2018 IPR023798 Ribosomal protein S7 domain UP12_00700 1ddfacb80886eb17d259a72e80f6b99f 156 SUPERFAMILY SSF47973 1 149 3.53E-61 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily UP12_00700 1ddfacb80886eb17d259a72e80f6b99f 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 11-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00700 1ddfacb80886eb17d259a72e80f6b99f 156 PIRSF PIRSF002122 5 156 5.8E-59 T 11-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 UP12_00700 1ddfacb80886eb17d259a72e80f6b99f 156 Gene3D G3DSA:1.10.455.10 2 156 2.0E-64 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily UP12_00700 1ddfacb80886eb17d259a72e80f6b99f 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.1E-70 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 UP12_00700 1ddfacb80886eb17d259a72e80f6b99f 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.472 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 UP12_01640 1459ce6e887b65bd8b8b0c1ec8fcfb8a 192 Gene3D G3DSA:2.60.60.30 19 187 3.6E-73 T 11-10-2018 UP12_01640 1459ce6e887b65bd8b8b0c1ec8fcfb8a 192 Pfam PF02342 TerD domain 1 188 4.2E-86 T 11-10-2018 IPR003325 TerD domain UP12_03870 8c50602cef1342b2ecff63ab9af46dea 325 SUPERFAMILY SSF53850 117 289 2.82E-7 T 11-10-2018 UP12_03870 8c50602cef1342b2ecff63ab9af46dea 325 Gene3D G3DSA:3.40.190.150 33 316 4.4E-48 T 11-10-2018 UP12_03870 8c50602cef1342b2ecff63ab9af46dea 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 113 319 7.3E-19 T 11-10-2018 IPR005064 Bordetella uptake gene GO:0030288 UP12_03870 8c50602cef1342b2ecff63ab9af46dea 325 Gene3D G3DSA:3.40.190.10 125 251 4.4E-48 T 11-10-2018 UP12_03870 8c50602cef1342b2ecff63ab9af46dea 325 PIRSF PIRSF017082 1 325 3.5E-77 T 11-10-2018 IPR005064 Bordetella uptake gene GO:0030288 UP12_03715 39b41fabef99072905f037d81cb86eb8 254 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 254 2.0E-93 T 11-10-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 UP12_03715 39b41fabef99072905f037d81cb86eb8 254 SUPERFAMILY SSF53448 1 254 4.06E-60 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_03715 39b41fabef99072905f037d81cb86eb8 254 Gene3D G3DSA:3.90.550.10 1 254 3.1E-66 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_03715 39b41fabef99072905f037d81cb86eb8 254 Pfam PF00483 Nucleotidyl transferase 2 221 8.9E-16 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UP12_06875 712d4c669e5af4949b4089c0ad423633 376 Pfam PF07687 Peptidase dimerisation domain 180 270 1.4E-10 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain UP12_06875 712d4c669e5af4949b4089c0ad423633 376 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 7 362 3.0E-87 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_06875 712d4c669e5af4949b4089c0ad423633 376 Pfam PF01546 Peptidase family M20/M25/M40 67 371 3.5E-24 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_06875 712d4c669e5af4949b4089c0ad423633 376 SUPERFAMILY SSF55031 179 284 9.81E-29 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_06875 712d4c669e5af4949b4089c0ad423633 376 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 4 373 61.87 T 11-10-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 UP12_06875 712d4c669e5af4949b4089c0ad423633 376 Gene3D G3DSA:3.30.70.360 174 288 2.1E-117 T 11-10-2018 UP12_06875 712d4c669e5af4949b4089c0ad423633 376 SUPERFAMILY SSF53187 4 369 5.5E-67 T 11-10-2018 UP12_06875 712d4c669e5af4949b4089c0ad423633 376 Gene3D G3DSA:3.40.630.10 7 359 2.1E-117 T 11-10-2018 UP12_06875 712d4c669e5af4949b4089c0ad423633 376 PIRSF PIRSF005962 2 376 1.8E-105 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 Hamap MF_00258 Glutamate racemase [murI]. 3 256 40.999 T 11-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 215 2.3E-39 T 11-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 11-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 254 1.5E-97 T 11-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 SUPERFAMILY SSF53681 109 257 3.27E-38 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 Gene3D G3DSA:3.40.50.1860 5 254 9.6E-97 T 11-10-2018 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 SUPERFAMILY SSF53681 4 107 6.21E-36 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 180 190 - T 11-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 UP12_12530 17252489ba1dc46eb1b02db5f40df7dc 271 Gene3D G3DSA:3.40.50.1860 95 207 9.6E-97 T 11-10-2018 UP12_04405 76b5860f46e42bd079e1380a571355d7 528 SUPERFAMILY SSF53850 36 527 2.78E-158 T 11-10-2018 UP12_04405 76b5860f46e42bd079e1380a571355d7 528 Gene3D G3DSA:3.40.190.10 204 516 2.7E-174 T 11-10-2018 UP12_04405 76b5860f46e42bd079e1380a571355d7 528 Gene3D G3DSA:3.90.76.10 51 203 2.7E-174 T 11-10-2018 UP12_04405 76b5860f46e42bd079e1380a571355d7 528 Gene3D G3DSA:3.10.105.10 286 503 2.7E-174 T 11-10-2018 UP12_04405 76b5860f46e42bd079e1380a571355d7 528 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 85 107 - T 11-10-2018 IPR023765 Solute-binding protein family 5, conserved site UP12_04405 76b5860f46e42bd079e1380a571355d7 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 447 4.7E-115 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain UP12_04405 76b5860f46e42bd079e1380a571355d7 528 PIRSF PIRSF002741 1 528 6.1E-145 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UP12_16260 f0a1369b42f6bcf28d07243304f576c8 212 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 204 36.342 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UP12_16260 f0a1369b42f6bcf28d07243304f576c8 212 Pfam PF00117 Glutamine amidotransferase class-I 4 201 1.3E-20 T 11-10-2018 IPR017926 Glutamine amidotransferase UP12_16260 f0a1369b42f6bcf28d07243304f576c8 212 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 203 5.7E-71 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UP12_16260 f0a1369b42f6bcf28d07243304f576c8 212 PIRSF PIRSF000495 1 207 1.5E-73 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UP12_16260 f0a1369b42f6bcf28d07243304f576c8 212 Gene3D G3DSA:3.40.50.880 1 212 3.5E-73 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_16260 f0a1369b42f6bcf28d07243304f576c8 212 SUPERFAMILY SSF52317 2 204 7.09E-55 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_10725 e1df020361c1a0cc3a84edb784255b06 162 Gene3D G3DSA:1.20.120.450 1 160 2.9E-36 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UP12_10725 e1df020361c1a0cc3a84edb784255b06 162 SUPERFAMILY SSF109854 7 156 3.82E-31 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UP12_10725 e1df020361c1a0cc3a84edb784255b06 162 Pfam PF12867 DinB superfamily 15 151 3.4E-17 T 11-10-2018 IPR024775 DinB-like domain UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 Pfam PF00137 ATP synthase subunit C 4 66 3.5E-15 T 11-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 15.972 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 SUPERFAMILY SSF81333 3 69 6.15E-20 T 11-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 11-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 9.0E-20 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 9.0E-20 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 9.0E-20 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 14 69 1.9E-22 T 11-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UP12_17205 6b2b43de5e9f3e673a321267b85efc30 70 Gene3D G3DSA:1.20.20.10 1 68 1.8E-28 T 11-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_10440 cc0f0c64e4550b3d9512f2e78e1e2248 159 Pfam PF13047 Protein of unknown function (DUF3907) 11 153 5.2E-57 T 11-10-2018 IPR025013 Protein of unknown function DUF3907 UP12_17015 6df770f5608d4f6a30936d0a8c189272 92 Gene3D G3DSA:1.10.10.60 1 92 6.1E-45 T 11-10-2018 UP12_17015 6df770f5608d4f6a30936d0a8c189272 92 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 11-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UP12_17015 6df770f5608d4f6a30936d0a8c189272 92 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 2.5E-46 T 11-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID UP12_17015 6df770f5608d4f6a30936d0a8c189272 92 Pfam PF12116 Stage III sporulation protein D 2 82 5.0E-41 T 11-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 SMART SM00279 176 211 4.4E-16 T 11-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 SUPERFAMILY SSF88723 3 156 5.02E-45 T 11-10-2018 IPR029060 PIN-like domain superfamily UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 Gene3D G3DSA:1.10.150.20 177 249 6.5E-82 T 11-10-2018 UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 Gene3D G3DSA:3.40.50.1010 5 276 6.5E-82 T 11-10-2018 UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 SMART SM00475 3 264 7.6E-117 T 11-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 SUPERFAMILY SSF47807 174 284 8.82E-28 T 11-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 264 2.4E-28 T 11-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 UP12_09885 691b2dbd0bf756e1135d02df95df86c6 295 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 172 2.3E-47 T 11-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 218 245 8.0E-79 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 171 195 8.0E-79 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 355 378 8.0E-79 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 284 303 8.0E-79 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 52 69 8.0E-79 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 26 51 8.0E-79 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 PRINTS PR00844 Glycosyl hydrolase family 48 signature 401 427 8.0E-79 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 Gene3D G3DSA:1.50.10.10 4 699 4.6E-234 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 Pfam PF02011 Glycosyl hydrolase family 48 488 699 2.2E-41 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 Pfam PF02011 Glycosyl hydrolase family 48 4 458 8.2E-200 T 11-10-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 Gene3D G3DSA:2.170.160.10 84 313 4.6E-234 T 11-10-2018 IPR023309 Endoglucanase F, domain 2 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 Gene3D G3DSA:4.10.870.10 589 679 4.6E-234 T 11-10-2018 IPR027390 Endoglucanase F, domain 3 UP12_08095 fee8795b4f8de085817eb572bdaaf28a 701 SUPERFAMILY SSF48208 3 700 2.92E-265 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 Gene3D G3DSA:3.40.50.300 324 576 1.9E-84 T 11-10-2018 UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 Gene3D G3DSA:1.20.1560.10 1 314 3.1E-88 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 SUPERFAMILY SSF52540 327 569 1.09E-80 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 SUPERFAMILY SSF90123 2 318 8.63E-78 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 Pfam PF00005 ABC transporter 351 497 1.9E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 SMART SM00382 359 545 4.8E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_09305 bc64efc11db27db0d7c498b84537f06d 577 Pfam PF00664 ABC transporter transmembrane region 18 286 6.8E-47 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_03335 481028e74b11519ef659b1f1737d79f1 162 Pfam PF00731 AIR carboxylase 5 152 1.9E-67 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UP12_03335 481028e74b11519ef659b1f1737d79f1 162 SMART SM01001 3 154 7.3E-110 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UP12_03335 481028e74b11519ef659b1f1737d79f1 162 PIRSF PIRSF001338 1 162 4.6E-72 T 11-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 UP12_03335 481028e74b11519ef659b1f1737d79f1 162 SUPERFAMILY SSF52255 4 160 4.32E-70 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 UP12_03335 481028e74b11519ef659b1f1737d79f1 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.998 T 11-10-2018 IPR033747 Class I PurE UP12_03335 481028e74b11519ef659b1f1737d79f1 162 Gene3D G3DSA:3.40.50.7700 1 162 4.9E-75 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 UP12_03335 481028e74b11519ef659b1f1737d79f1 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 161 4.6E-70 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 UP12_16270 b23641e608c0f839b913b71de04d9502 429 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 31 423 6.8E-170 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 Pfam PF00815 Histidinol dehydrogenase 24 423 6.4E-172 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 SUPERFAMILY SSF53720 25 423 2.94E-86 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 132 158 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 358 376 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 248 267 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 317 342 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 167 193 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 31 55 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 226 247 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PRINTS PR00083 Histidinol dehydrogenase signature 197 222 1.6E-87 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 424 42.79 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 Gene3D G3DSA:3.40.50.1980 30 228 1.2E-127 T 11-10-2018 UP12_16270 b23641e608c0f839b913b71de04d9502 429 PIRSF PIRSF000099 2 427 2.9E-171 T 11-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 226 258 - T 11-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 UP12_16270 b23641e608c0f839b913b71de04d9502 429 Gene3D G3DSA:3.40.50.1980 230 346 1.2E-127 T 11-10-2018 UP12_01740 af3abd5ef5a1a967725f65bf4b8bb82e 348 Gene3D G3DSA:3.40.50.720 2 117 1.1E-30 T 11-10-2018 UP12_01740 af3abd5ef5a1a967725f65bf4b8bb82e 348 Gene3D G3DSA:3.30.360.10 118 343 4.5E-32 T 11-10-2018 UP12_01740 af3abd5ef5a1a967725f65bf4b8bb82e 348 SUPERFAMILY SSF55347 128 271 2.62E-20 T 11-10-2018 UP12_01740 af3abd5ef5a1a967725f65bf4b8bb82e 348 SUPERFAMILY SSF51735 3 148 3.18E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_01740 af3abd5ef5a1a967725f65bf4b8bb82e 348 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 130 216 2.7E-17 T 11-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 UP12_01740 af3abd5ef5a1a967725f65bf4b8bb82e 348 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 117 2.2E-25 T 11-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 SUPERFAMILY SSF161093 278 448 6.41E-53 T 11-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 Pfam PF01769 Divalent cation transporter 320 441 4.3E-31 T 11-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 SUPERFAMILY SSF158791 8 132 8.76E-27 T 11-10-2018 UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 TIGRFAM TIGR00400 mgtE: magnesium transporter 4 450 5.2E-202 T 11-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 SUPERFAMILY SSF54631 135 266 8.46E-31 T 11-10-2018 UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 Gene3D G3DSA:1.10.357.20 273 449 2.7E-60 T 11-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 Pfam PF00571 CBS domain 200 253 5.7E-8 T 11-10-2018 IPR000644 CBS domain UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 Pfam PF00571 CBS domain 136 192 2.7E-6 T 11-10-2018 IPR000644 CBS domain UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 Gene3D G3DSA:3.10.580.10 133 259 4.3E-42 T 11-10-2018 UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 Pfam PF03448 MgtE intracellular N domain 33 133 1.6E-22 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 SMART SM00924 33 136 1.8E-27 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 Gene3D G3DSA:1.25.60.10 6 131 2.5E-20 T 11-10-2018 IPR038076 MgtE, N-terminal domain superfamily UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 SMART SM00116 143 196 11.0 T 11-10-2018 IPR000644 CBS domain UP12_06450 a0c4d85b044d9bc9deeca7794f29f6ab 452 SMART SM00116 207 255 9.0E-6 T 11-10-2018 IPR000644 CBS domain UP12_10695 39cf0a7772277deb2fb2cfaf95ece319 411 PRINTS PR01035 Tetracycline resistance protein signature 165 185 5.7E-8 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_10695 39cf0a7772277deb2fb2cfaf95ece319 411 PRINTS PR01035 Tetracycline resistance protein signature 137 159 5.7E-8 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_10695 39cf0a7772277deb2fb2cfaf95ece319 411 PRINTS PR01035 Tetracycline resistance protein signature 79 103 5.7E-8 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_10695 39cf0a7772277deb2fb2cfaf95ece319 411 SUPERFAMILY SSF103473 1 399 1.57E-57 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_10695 39cf0a7772277deb2fb2cfaf95ece319 411 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_10695 39cf0a7772277deb2fb2cfaf95ece319 411 Gene3D G3DSA:1.20.1250.20 10 386 2.7E-51 T 11-10-2018 UP12_10695 39cf0a7772277deb2fb2cfaf95ece319 411 Pfam PF07690 Major Facilitator Superfamily 15 346 8.4E-38 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_07055 05ca3ea363f18fa5e94bd7ff0efd2f21 222 Pfam PF10368 Putative cell-wall binding lipoprotein 17 216 1.7E-64 T 11-10-2018 IPR019454 Putative cell-wall binding lipoprotein YkyA-like UP12_07055 05ca3ea363f18fa5e94bd7ff0efd2f21 222 SUPERFAMILY SSF140423 25 214 4.84E-51 T 11-10-2018 IPR036785 YkyA-like superfamily UP12_07055 05ca3ea363f18fa5e94bd7ff0efd2f21 222 Gene3D G3DSA:1.20.120.570 22 214 7.1E-42 T 11-10-2018 IPR036785 YkyA-like superfamily UP12_01465 d1610a8f8704c5d92e198fc982ba4e1d 105 SUPERFAMILY SSF46785 10 96 3.9E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_01465 d1610a8f8704c5d92e198fc982ba4e1d 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 5.9E-21 T 11-10-2018 IPR005149 Transcription regulator PadR, N-terminal UP12_01465 d1610a8f8704c5d92e198fc982ba4e1d 105 Gene3D G3DSA:1.10.10.10 1 103 2.0E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06505 018582ec619d4a15f401a35bcb928e2c 395 Pfam PF12791 Anti-sigma factor N-terminus 7 56 2.2E-13 T 11-10-2018 IPR024449 Anti-sigma factor RsgI, N-terminal UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 Gene3D G3DSA:2.170.8.10 38 330 2.5E-225 T 11-10-2018 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 SUPERFAMILY SSF68923 12 212 7.67E-80 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 1 527 8.1E-265 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 SUPERFAMILY SSF53795 213 516 2.75E-134 T 11-10-2018 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 Gene3D G3DSA:3.90.228.20 214 513 2.5E-225 T 11-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 528 55.712 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 PIRSF PIRSF006294 1 527 1.4E-241 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 Gene3D G3DSA:3.40.449.10 28 213 2.5E-225 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 UP12_13745 2f4de458e6d9da038d9160e50f518c96 528 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 481 6.0E-224 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 SMART SM00354 2 72 2.4E-31 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 Pfam PF13377 Periplasmic binding protein-like domain 169 332 2.9E-36 T 11-10-2018 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 Gene3D G3DSA:3.40.50.2300 62 309 5.7E-66 T 11-10-2018 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 3.7E-19 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 11-10-2018 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 SUPERFAMILY SSF53822 62 333 3.03E-71 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 SUPERFAMILY SSF47413 2 60 7.5E-19 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 Gene3D G3DSA:1.10.260.40 1 60 3.5E-23 T 11-10-2018 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 Gene3D G3DSA:3.40.50.2300 160 289 5.7E-66 T 11-10-2018 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 3.1E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_15605 d0b4d79b681e69a90f9976d6ac6aa45a 336 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 3.1E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_12290 87f483714823678cbf862726c71192d2 224 Gene3D G3DSA:3.40.140.10 100 224 1.9E-46 T 11-10-2018 UP12_12290 87f483714823678cbf862726c71192d2 224 Pfam PF04002 RadC-like JAB domain 103 222 1.9E-46 T 11-10-2018 IPR025657 RadC-like JAB domain UP12_12290 87f483714823678cbf862726c71192d2 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 11-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site UP12_12290 87f483714823678cbf862726c71192d2 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 6.3E-87 T 11-10-2018 IPR001405 Uncharacterised protein family UPF0758 UP12_12290 87f483714823678cbf862726c71192d2 224 Gene3D G3DSA:1.10.150.20 47 87 2.0E-7 T 11-10-2018 UP12_12290 87f483714823678cbf862726c71192d2 224 SUPERFAMILY SSF47781 15 89 3.81E-9 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_12290 87f483714823678cbf862726c71192d2 224 SUPERFAMILY SSF102712 153 191 2.62E-5 T 11-10-2018 UP12_14135 e3efbcf58caacfd38dc23620cbca345b 270 SMART SM00644 13 153 5.2E-37 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_14135 e3efbcf58caacfd38dc23620cbca345b 270 SUPERFAMILY SSF47090 196 266 4.97E-17 T 11-10-2018 IPR036365 PGBD-like superfamily UP12_14135 e3efbcf58caacfd38dc23620cbca345b 270 Pfam PF01471 Putative peptidoglycan binding domain 204 265 5.2E-17 T 11-10-2018 IPR002477 Peptidoglycan binding-like UP12_14135 e3efbcf58caacfd38dc23620cbca345b 270 Gene3D G3DSA:1.10.101.10 194 270 1.8E-18 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UP12_14135 e3efbcf58caacfd38dc23620cbca345b 270 SUPERFAMILY SSF55846 2 153 1.58E-46 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_14135 e3efbcf58caacfd38dc23620cbca345b 270 Gene3D G3DSA:3.40.80.10 1 154 1.8E-55 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_14135 e3efbcf58caacfd38dc23620cbca345b 270 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 22 140 5.8E-25 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_08445 8928363a76e3e9fe50a5711b3617cae2 109 Pfam PF14157 YmzC-like protein 44 96 2.1E-25 T 11-10-2018 IPR025448 YmzC-like protein UP12_04740 f4823e2cc4c95c14fb39e31008e1f801 188 SUPERFAMILY SSF63817 50 187 9.42E-34 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_04740 f4823e2cc4c95c14fb39e31008e1f801 188 Pfam PF04203 Sortase family 64 186 2.7E-26 T 11-10-2018 IPR005754 Sortase family UP12_04740 f4823e2cc4c95c14fb39e31008e1f801 188 Gene3D G3DSA:2.40.260.10 23 188 6.7E-41 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_04740 f4823e2cc4c95c14fb39e31008e1f801 188 TIGRFAM TIGR01076 sortase_fam: sortase 62 187 7.9E-40 T 11-10-2018 IPR005754 Sortase family UP12_09745 5dd283c21000b66f2553201e6a60fae3 184 Pfam PF02630 SCO1/SenC 4 164 9.2E-53 T 11-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_09745 5dd283c21000b66f2553201e6a60fae3 184 Gene3D G3DSA:3.40.30.10 13 182 5.4E-59 T 11-10-2018 UP12_09745 5dd283c21000b66f2553201e6a60fae3 184 SUPERFAMILY SSF52833 21 183 3.8E-43 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_00695 43e90606294572f7b223a229709d80a9 139 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 Gene3D G3DSA:2.40.50.140 1 139 2.1E-61 T 11-10-2018 UP12_00695 43e90606294572f7b223a229709d80a9 139 SUPERFAMILY SSF50249 2 137 3.34E-48 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_00695 43e90606294572f7b223a229709d80a9 139 PRINTS PR01034 Ribosomal protein S12 signature 40 55 9.1E-58 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 PRINTS PR01034 Ribosomal protein S12 signature 55 70 9.1E-58 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 PRINTS PR01034 Ribosomal protein S12 signature 90 107 9.1E-58 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 PRINTS PR01034 Ribosomal protein S12 signature 123 135 9.1E-58 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 PRINTS PR01034 Ribosomal protein S12 signature 71 90 9.1E-58 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 PRINTS PR01034 Ribosomal protein S12 signature 107 123 9.1E-58 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 40.429 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00695 43e90606294572f7b223a229709d80a9 139 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 1.4E-67 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00695 43e90606294572f7b223a229709d80a9 139 Pfam PF00164 Ribosomal protein S12/S23 37 136 5.4E-37 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00695 43e90606294572f7b223a229709d80a9 139 PIRSF PIRSF002133 1 137 1.9E-48 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_19130 93c2c5e70b736c3ba5a15719d6908122 208 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 43 181 1.3E-68 T 11-10-2018 IPR009665 Protein of unknown function DUF1256 UP12_19130 93c2c5e70b736c3ba5a15719d6908122 208 SUPERFAMILY SSF53163 3 194 4.97E-58 T 11-10-2018 IPR023430 Peptidase HybD-like domain superfamily UP12_19130 93c2c5e70b736c3ba5a15719d6908122 208 Pfam PF06866 Protein of unknown function (DUF1256) 17 179 1.2E-67 T 11-10-2018 IPR009665 Protein of unknown function DUF1256 UP12_02275 346e309e16011fd2c4bfa98ee2df56b2 253 Pfam PF01614 Bacterial transcriptional regulator 121 245 3.5E-31 T 11-10-2018 IPR014757 Transcription regulator IclR, C-terminal UP12_02275 346e309e16011fd2c4bfa98ee2df56b2 253 Gene3D G3DSA:1.10.10.10 4 76 3.5E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02275 346e309e16011fd2c4bfa98ee2df56b2 253 Gene3D G3DSA:3.30.450.40 77 252 1.7E-50 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_02275 346e309e16011fd2c4bfa98ee2df56b2 253 SMART SM00346 5 93 2.6E-23 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UP12_02275 346e309e16011fd2c4bfa98ee2df56b2 253 SUPERFAMILY SSF55781 61 249 3.34E-47 T 11-10-2018 UP12_02275 346e309e16011fd2c4bfa98ee2df56b2 253 SUPERFAMILY SSF46785 6 77 1.39E-12 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02275 346e309e16011fd2c4bfa98ee2df56b2 253 Pfam PF09339 IclR helix-turn-helix domain 8 56 1.2E-11 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 SUPERFAMILY SSF46894 138 207 1.36E-21 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 SMART SM00421 147 204 5.0E-26 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 Gene3D G3DSA:3.40.50.12740 1 208 4.0E-69 T 11-10-2018 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 SUPERFAMILY SSF52172 1 133 1.85E-34 T 11-10-2018 IPR011006 CheY-like superfamily UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.7E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.7E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.7E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 Pfam PF00072 Response regulator receiver domain 3 113 2.3E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 SMART SM00448 1 114 2.7E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 5.2E-22 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_04815 4bf70dbc3988ab5aed8d6aed39d9f1c0 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_12335 e87740259932a0b1c8e2775ea6da421c 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 274 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_12335 e87740259932a0b1c8e2775ea6da421c 429 Gene3D G3DSA:3.40.640.10 73 320 9.8E-184 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_12335 e87740259932a0b1c8e2775ea6da421c 429 Pfam PF00202 Aminotransferase class-III 35 399 8.5E-77 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_12335 e87740259932a0b1c8e2775ea6da421c 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 428 104.232 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UP12_12335 e87740259932a0b1c8e2775ea6da421c 429 Gene3D G3DSA:3.90.1150.10 11 422 9.8E-184 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_12335 e87740259932a0b1c8e2775ea6da421c 429 SUPERFAMILY SSF53383 5 428 2.67E-132 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_12335 e87740259932a0b1c8e2775ea6da421c 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 427 2.4E-201 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 SUPERFAMILY SSF141734 5 108 4.18E-47 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 5 207 38.877 T 11-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 Gene3D G3DSA:3.10.20.400 1 93 4.7E-41 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 Gene3D G3DSA:1.10.287.1080 116 208 8.2E-35 T 11-10-2018 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 120 206 9.9E-19 T 11-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 30 101 1.8E-34 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 106 29.64 T 11-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 120 202 1.7E-33 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 116 202 21.344 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 SUPERFAMILY SSF101386 118 206 2.8E-28 T 11-10-2018 UP12_16245 3b420610eae10aa0e240658efdb17c04 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 101 7.0E-21 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 UP12_01020 f98f2e2535f025a7539933dafe107c3d 303 Gene3D G3DSA:3.40.50.10490 3 221 8.6E-77 T 11-10-2018 UP12_01020 f98f2e2535f025a7539933dafe107c3d 303 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 188 205 - T 11-10-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 UP12_01020 f98f2e2535f025a7539933dafe107c3d 303 Pfam PF13580 SIS domain 42 168 9.7E-11 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_01020 f98f2e2535f025a7539933dafe107c3d 303 TIGRFAM TIGR00274 TIGR00274: N-acetylmuramic acid 6-phosphate etherase 9 298 3.3E-133 T 11-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 UP12_01020 f98f2e2535f025a7539933dafe107c3d 303 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 5 298 40.946 T 11-10-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00520+4.2.1.126 UP12_01020 f98f2e2535f025a7539933dafe107c3d 303 Gene3D G3DSA:1.10.8.1080 222 300 2.0E-27 T 11-10-2018 UP12_01020 f98f2e2535f025a7539933dafe107c3d 303 SUPERFAMILY SSF53697 9 251 5.34E-70 T 11-10-2018 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 623 1.0E-301 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 5.2E-39 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 SMART SM00861 316 481 3.2E-64 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 SUPERFAMILY SSF52922 489 623 1.57E-33 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 Gene3D G3DSA:3.40.50.970 313 489 6.8E-66 T 11-10-2018 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 44.839 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 11-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 Pfam PF02780 Transketolase, C-terminal domain 493 615 4.6E-33 T 11-10-2018 IPR033248 Transketolase, C-terminal domain UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 SUPERFAMILY SSF52518 316 503 2.59E-55 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 SUPERFAMILY SSF52518 7 378 3.13E-69 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 Gene3D G3DSA:3.40.50.920 493 627 9.5E-41 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_10965 8f7610aa804dc1ae8b3331837744eaec 633 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 278 2.4E-114 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_09160 6efd74840dc28343ea71a65a6cd05791 512 SUPERFAMILY SSF51445 67 333 4.01E-26 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_09160 6efd74840dc28343ea71a65a6cd05791 512 Gene3D G3DSA:2.60.40.10 419 512 4.4E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_09160 6efd74840dc28343ea71a65a6cd05791 512 Pfam PF02638 Glycosyl hydrolase-like 10 40 361 6.8E-117 T 11-10-2018 IPR003790 Glycosyl hydrolase-like 10 UP12_09160 6efd74840dc28343ea71a65a6cd05791 512 Gene3D G3DSA:3.20.20.70 89 254 7.4E-10 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_01555 e975546089c79bc2e06659ee48cb0798 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 363 1.7E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_01555 e975546089c79bc2e06659ee48cb0798 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 1.7E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_01555 e975546089c79bc2e06659ee48cb0798 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 1.7E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_01555 e975546089c79bc2e06659ee48cb0798 428 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 377 1.7E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_01555 e975546089c79bc2e06659ee48cb0798 428 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 421 8.9E-18 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_01555 e975546089c79bc2e06659ee48cb0798 428 Gene3D G3DSA:3.30.565.10 266 421 5.2E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_01555 e975546089c79bc2e06659ee48cb0798 428 SUPERFAMILY SSF55874 275 420 4.19E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_01555 e975546089c79bc2e06659ee48cb0798 428 SMART SM00387 312 423 1.5E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_19300 0c23db0ed79dd8438b19121de2629277 325 Pfam PF00877 NlpC/P60 family 216 320 3.6E-25 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_19300 0c23db0ed79dd8438b19121de2629277 325 SUPERFAMILY SSF54001 200 324 1.4E-33 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_19300 0c23db0ed79dd8438b19121de2629277 325 Gene3D G3DSA:1.10.530.10 24 184 9.2E-54 T 11-10-2018 UP12_19300 0c23db0ed79dd8438b19121de2629277 325 SUPERFAMILY SSF53955 33 133 1.03E-11 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_19300 0c23db0ed79dd8438b19121de2629277 325 Gene3D G3DSA:3.90.1720.10 194 325 1.9E-36 T 11-10-2018 UP12_19300 0c23db0ed79dd8438b19121de2629277 325 Pfam PF13702 Lysozyme-like 27 182 6.2E-54 T 11-10-2018 UP12_07335 00055bec22bccc38801787826de4df6d 143 Gene3D G3DSA:2.40.330.20 1 141 1.0E-54 T 11-10-2018 IPR038619 MraZ superfamily UP12_07335 00055bec22bccc38801787826de4df6d 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 138 4.0E-73 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UP12_07335 00055bec22bccc38801787826de4df6d 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 60.291 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UP12_07335 00055bec22bccc38801787826de4df6d 143 Pfam PF02381 MraZ protein, putative antitoxin-like 1 70 1.3E-23 T 11-10-2018 IPR020603 MraZ domain UP12_07335 00055bec22bccc38801787826de4df6d 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 141 1.4E-26 T 11-10-2018 IPR020603 MraZ domain UP12_07335 00055bec22bccc38801787826de4df6d 143 SUPERFAMILY SSF89447 1 136 1.99E-53 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily UP12_07335 00055bec22bccc38801787826de4df6d 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 143 4.7E-64 T 11-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 UP12_01005 a75b0005a7eb11e1f4cbe4e7fd7c57f2 451 SUPERFAMILY SSF56601 53 417 4.55E-78 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_01005 a75b0005a7eb11e1f4cbe4e7fd7c57f2 451 Gene3D G3DSA:3.40.710.10 44 425 2.6E-88 T 11-10-2018 UP12_01005 a75b0005a7eb11e1f4cbe4e7fd7c57f2 451 Hamap MF_01034 UPF0214 protein YfeW [yfeW]. 1 451 65.103 T 11-10-2018 IPR022849 Peptidase S12, UPF0214, YfeW-type UP12_01005 a75b0005a7eb11e1f4cbe4e7fd7c57f2 451 Pfam PF00144 Beta-lactamase 64 430 1.1E-68 T 11-10-2018 IPR001466 Beta-lactamase-related UP12_10365 08308c517c61cbc139aa403469257a49 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 4.7E-8 T 11-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UP12_10365 08308c517c61cbc139aa403469257a49 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 4.7E-8 T 11-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UP12_10365 08308c517c61cbc139aa403469257a49 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 4.7E-8 T 11-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 UP12_10365 08308c517c61cbc139aa403469257a49 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 1.6E-21 T 11-10-2018 UP12_10365 08308c517c61cbc139aa403469257a49 82 Gene3D G3DSA:3.30.70.20 2 82 1.4E-34 T 11-10-2018 UP12_10365 08308c517c61cbc139aa403469257a49 82 SUPERFAMILY SSF54862 4 72 2.89E-13 T 11-10-2018 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 PIRSF PIRSF000770 2 239 1.1E-79 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 Gene3D G3DSA:1.20.120.1810 30 131 1.2E-25 T 11-10-2018 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 7 239 5.6E-135 T 11-10-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 Pfam PF04545 Sigma-70, region 4 180 233 1.0E-16 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 SUPERFAMILY SSF88946 25 131 3.4E-35 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 7.1E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 7.1E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 7.1E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 7.1E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 1.1E-36 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 Pfam PF04542 Sigma-70 region 2 62 131 1.8E-18 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 SUPERFAMILY SSF88659 143 236 1.05E-21 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 Gene3D G3DSA:1.10.10.10 167 239 7.9E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_07430 2c1d69045868f05e810fe1a270cbf4c1 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 Gene3D G3DSA:3.40.1160.10 1 255 2.0E-84 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 SUPERFAMILY SSF55021 260 346 1.83E-11 T 11-10-2018 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 65 401 1.3E-92 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 403 4.6E-144 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 Pfam PF13840 ACT domain 337 398 9.3E-21 T 11-10-2018 IPR027795 CASTOR, ACT domain UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 SUPERFAMILY SSF55021 335 403 9.51E-16 T 11-10-2018 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 Pfam PF00696 Amino acid kinase family 2 235 7.6E-47 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 PIRSF PIRSF000726 1 65 8.9E-9 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 PIRSF PIRSF000726 60 404 3.6E-91 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 SUPERFAMILY SSF53633 3 248 5.76E-69 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 11-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08200 99df38332a1d49c55b4275ea2a4371b5 404 Gene3D G3DSA:3.30.2130.10 256 404 1.3E-31 T 11-10-2018 UP12_07675 353fd423142e56734136e2692bdf9587 256 SMART SM00332 1 243 1.7E-30 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_07675 353fd423142e56734136e2692bdf9587 256 Gene3D G3DSA:3.60.40.10 1 248 2.1E-74 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_07675 353fd423142e56734136e2692bdf9587 256 SUPERFAMILY SSF81606 2 245 1.03E-66 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_07675 353fd423142e56734136e2692bdf9587 256 Pfam PF13672 Protein phosphatase 2C 14 222 2.2E-22 T 11-10-2018 UP12_07675 353fd423142e56734136e2692bdf9587 256 SMART SM00331 9 245 3.7E-63 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 Gene3D G3DSA:1.10.10.10 7 145 1.7E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 SUPERFAMILY SSF46785 12 142 2.59E-30 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.5E-15 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 3.5E-15 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.5E-15 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 3.5E-15 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 Pfam PF01047 MarR family 34 91 2.2E-17 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 SMART SM00418 29 108 0.005 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_18360 aef1eaeaffa69f8d8ccb2518b819ce3a 147 SMART SM00347 27 127 1.5E-29 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_17645 f94b2e8b3970997bf55e65cc93573348 321 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 307 7.3E-86 T 11-10-2018 IPR016040 NAD(P)-binding domain UP12_17645 f94b2e8b3970997bf55e65cc93573348 321 SUPERFAMILY SSF51735 2 316 6.09E-93 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17645 f94b2e8b3970997bf55e65cc93573348 321 Gene3D G3DSA:3.90.25.10 193 313 3.7E-124 T 11-10-2018 UP12_17645 f94b2e8b3970997bf55e65cc93573348 321 Gene3D G3DSA:3.40.50.720 5 306 3.7E-124 T 11-10-2018 UP12_17645 f94b2e8b3970997bf55e65cc93573348 321 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 315 7.8E-144 T 11-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 UP12_08120 7112f2e7b3e5829d323703fbd418d9c8 96 Gene3D G3DSA:3.30.1230.10 2 95 2.8E-34 T 11-10-2018 IPR035931 YlxR-like superfamily UP12_08120 7112f2e7b3e5829d323703fbd418d9c8 96 SUPERFAMILY SSF64376 5 89 1.96E-26 T 11-10-2018 IPR035931 YlxR-like superfamily UP12_08120 7112f2e7b3e5829d323703fbd418d9c8 96 Pfam PF04296 Protein of unknown function (DUF448) 10 82 3.5E-26 T 11-10-2018 IPR007393 Domain of unknown function DUF448 UP12_10090 15c299607232ae4806cfb6a83a98c626 111 Gene3D G3DSA:1.10.287.1080 2 111 6.2E-36 T 11-10-2018 UP12_10090 15c299607232ae4806cfb6a83a98c626 111 SUPERFAMILY SSF101386 3 105 3.2E-28 T 11-10-2018 UP12_10090 15c299607232ae4806cfb6a83a98c626 111 PIRSF PIRSF029904 2 111 1.6E-53 T 11-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD UP12_10090 15c299607232ae4806cfb6a83a98c626 111 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 105 3.3E-20 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 SUPERFAMILY SSF50129 287 332 1.93E-6 T 11-10-2018 IPR011032 GroES-like superfamily UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 Gene3D G3DSA:3.90.180.10 9 331 8.7E-138 T 11-10-2018 UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 SUPERFAMILY SSF51735 123 298 3.89E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 Gene3D G3DSA:3.40.50.720 125 302 8.7E-138 T 11-10-2018 UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 SUPERFAMILY SSF50129 1 142 5.9E-45 T 11-10-2018 IPR011032 GroES-like superfamily UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 Pfam PF00107 Zinc-binding dehydrogenase 157 292 4.4E-26 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 SMART SM00829 15 331 1.8E-5 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_03815 9d40b99c90b155a02b259978357f5d0a 334 Pfam PF16884 N-terminal domain of oxidoreductase 5 112 1.2E-42 T 11-10-2018 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 Pfam PF13091 PLD-like domain 349 470 4.1E-28 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 Pfam PF13091 PLD-like domain 158 301 1.0E-14 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 Hamap MF_01916 Cardiolipin synthase. 36 506 44.156 T 11-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 Gene3D G3DSA:3.30.870.10 337 480 1.4E-27 T 11-10-2018 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 Pfam PF13396 Phospholipase_D-nuclease N-terminal 42 84 1.7E-8 T 11-10-2018 IPR027379 Cardiolipin synthase N-terminal UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 SUPERFAMILY SSF56024 129 336 2.2E-53 T 11-10-2018 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 35 506 1.0E-184 T 11-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 SMART SM00155 241 268 6.0E-6 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 SMART SM00155 419 446 5.3E-8 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 Gene3D G3DSA:3.30.870.10 137 328 3.1E-49 T 11-10-2018 UP12_05740 4255c3c9f2a5f43356032f3c90d75783 506 SUPERFAMILY SSF56024 293 493 6.5E-49 T 11-10-2018 UP12_05060 afda55bda1513a47da494eda5b3db957 291 Pfam PF13616 PPIC-type PPIASE domain 134 227 4.3E-25 T 11-10-2018 UP12_05060 afda55bda1513a47da494eda5b3db957 291 Hamap MF_01145 Foldase protein PrsA [prsA]. 2 281 19.934 T 11-10-2018 IPR023059 Foldase protein PrsA GO:0003755 UP12_05060 afda55bda1513a47da494eda5b3db957 291 Gene3D G3DSA:3.10.50.40 135 227 1.5E-36 T 11-10-2018 UP12_05060 afda55bda1513a47da494eda5b3db957 291 SUPERFAMILY SSF109998 26 163 1.31E-17 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily UP12_05060 afda55bda1513a47da494eda5b3db957 291 SUPERFAMILY SSF54534 119 225 2.03E-27 T 11-10-2018 UP12_04110 58ec7b39c757d28944614b85de6e3090 395 Pfam PF07690 Major Facilitator Superfamily 10 322 8.2E-40 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_04110 58ec7b39c757d28944614b85de6e3090 395 Gene3D G3DSA:1.20.1250.20 1 378 2.4E-49 T 11-10-2018 UP12_04110 58ec7b39c757d28944614b85de6e3090 395 PRINTS PR01035 Tetracycline resistance protein signature 42 61 3.0E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_04110 58ec7b39c757d28944614b85de6e3090 395 PRINTS PR01035 Tetracycline resistance protein signature 12 28 3.0E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_04110 58ec7b39c757d28944614b85de6e3090 395 PRINTS PR01035 Tetracycline resistance protein signature 266 287 3.0E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_04110 58ec7b39c757d28944614b85de6e3090 395 PRINTS PR01035 Tetracycline resistance protein signature 100 121 3.0E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_04110 58ec7b39c757d28944614b85de6e3090 395 SUPERFAMILY SSF103473 4 385 1.57E-61 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_15775 f4cc6beb60099cbf345dbf6e1ab83b92 101 Pfam PF02583 Metal-sensitive transcriptional repressor 17 97 4.6E-33 T 11-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 UP12_15775 f4cc6beb60099cbf345dbf6e1ab83b92 101 Gene3D G3DSA:1.20.58.1000 1 100 4.8E-37 T 11-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily UP12_02535 ce47028d36868b0141958e1a58f8b463 386 Pfam PF01168 Alanine racemase, N-terminal domain 14 233 6.0E-70 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 Gene3D G3DSA:3.20.20.10 16 238 2.0E-137 T 11-10-2018 IPR029066 PLP-binding barrel UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 166 177 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 355 368 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 206 233 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 264 279 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 33 49 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 281 296 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 131 143 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 69 87 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 PRINTS PR00992 Alanine racemase signature 301 318 1.2E-72 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 Pfam PF00842 Alanine racemase, C-terminal domain 248 372 7.4E-46 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 TIGRFAM TIGR00492 alr: alanine racemase 8 374 9.7E-138 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 Gene3D G3DSA:2.40.37.10 14 370 2.0E-137 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 38 48 - T 11-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 SUPERFAMILY SSF51419 14 244 1.59E-66 T 11-10-2018 IPR029066 PLP-binding barrel UP12_02535 ce47028d36868b0141958e1a58f8b463 386 SMART SM01005 248 373 1.0E-72 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 Hamap MF_01201 Alanine racemase. 7 373 36.107 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_02535 ce47028d36868b0141958e1a58f8b463 386 SUPERFAMILY SSF50621 243 383 2.2E-51 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UP12_09545 48aac2f526b861e4e2c35b4f57ccb3d5 192 SUPERFAMILY SSF49329 42 186 3.66E-42 T 11-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UP12_09545 48aac2f526b861e4e2c35b4f57ccb3d5 192 Gene3D G3DSA:2.60.40.200 41 191 2.3E-58 T 11-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UP12_09545 48aac2f526b861e4e2c35b4f57ccb3d5 192 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 50 186 2.1E-40 T 11-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UP12_09545 48aac2f526b861e4e2c35b4f57ccb3d5 192 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 175 186 - T 11-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 UP12_12265 ab65efc45681b21cb446c16f38abb114 267 Pfam PF13614 AAA domain 4 160 2.8E-25 T 11-10-2018 IPR025669 AAA domain UP12_12265 ab65efc45681b21cb446c16f38abb114 267 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 263 3.3E-126 T 11-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 UP12_12265 ab65efc45681b21cb446c16f38abb114 267 PIRSF PIRSF003092 1 267 2.3E-95 T 11-10-2018 IPR025501 ATP binding protein MinD UP12_12265 ab65efc45681b21cb446c16f38abb114 267 Gene3D G3DSA:3.40.50.300 3 255 3.6E-70 T 11-10-2018 UP12_12265 ab65efc45681b21cb446c16f38abb114 267 SUPERFAMILY SSF52540 5 259 2.8E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 SMART SM00387 320 427 3.6E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 SUPERFAMILY SSF47384 198 277 4.32E-13 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 426 5.3E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 276 1.5E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 424 4.4E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 4.4E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 405 4.4E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 386 4.4E-10 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 Gene3D G3DSA:3.30.565.10 275 425 1.6E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 Pfam PF07694 5TMR of 5TMR-LYT 34 148 2.2E-6 T 11-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 SUPERFAMILY SSF55874 271 424 2.88E-36 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 Gene3D G3DSA:1.10.287.130 197 274 4.6E-18 T 11-10-2018 UP12_14840 deab2e6fea8a2288422b7c64e995b07f 430 SMART SM00388 211 279 1.2E-10 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_12875 8ef24f931d92cccc2de29a9b6592ff08 573 Pfam PF00501 AMP-binding enzyme 33 461 1.8E-112 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_12875 8ef24f931d92cccc2de29a9b6592ff08 573 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 546 7.5E-20 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_12875 8ef24f931d92cccc2de29a9b6592ff08 573 Gene3D G3DSA:3.40.50.12780 12 453 3.0E-129 T 11-10-2018 UP12_12875 8ef24f931d92cccc2de29a9b6592ff08 573 Gene3D G3DSA:3.30.300.310 458 562 2.8E-31 T 11-10-2018 UP12_12875 8ef24f931d92cccc2de29a9b6592ff08 573 ProSitePatterns PS00455 Putative AMP-binding domain signature. 214 225 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_12875 8ef24f931d92cccc2de29a9b6592ff08 573 SUPERFAMILY SSF56801 17 556 3.14E-155 T 11-10-2018 UP12_15245 e0794774a5ebb7652a6594f99c7be7ec 254 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 142 231 1.5E-29 T 11-10-2018 IPR014197 Sporulation protein YunB UP12_15245 e0794774a5ebb7652a6594f99c7be7ec 254 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 13 235 1.1E-61 T 11-10-2018 IPR014197 Sporulation protein YunB UP12_15245 e0794774a5ebb7652a6594f99c7be7ec 254 PIRSF PIRSF021383 1 248 2.6E-87 T 11-10-2018 IPR014197 Sporulation protein YunB UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.40.50.12780 464 865 5.5E-125 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF52777 2578 2776 1.22E-41 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.30.559.30 2760 2998 1.7E-132 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1325 1441 3.0E-43 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF00550 Phosphopantetheine attachment site 2501 2564 1.8E-13 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF00550 Phosphopantetheine attachment site 982 1045 1.6E-12 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF47336 974 1082 1.7E-16 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:1.10.1200.10 967 1054 6.4E-21 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF52777 2763 3003 3.89E-52 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.30.559.30 198 453 2.0E-114 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.30.70.250 1722 1783 2.5E-129 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SMART SM00823 Phosphopantetheine attachment site 980 1049 8.5E-6 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SMART SM00823 Phosphopantetheine attachment site 2499 2568 0.0029 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.30.559.10 2585 2949 1.7E-132 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1593 1889 6.1E-65 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF53901 1065 1491 3.1E-86 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF00501 AMP-binding enzyme 478 871 1.4E-95 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF47336 2491 2596 1.24E-18 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF52777 20 194 1.11E-40 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF08659 KR domain 2207 2396 1.4E-36 T 11-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.40.50.720 1939 2465 1.6E-67 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF52777 198 445 1.45E-50 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1068 1317 1.3E-67 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:1.10.1200.10 2486 2573 4.2E-21 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF51735 2205 2387 2.17E-21 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF13193 AMP-binding enzyme C-terminal domain 879 952 1.3E-10 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.30.70.3290 1508 1919 2.5E-129 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1445 1554 3.0E-18 T 11-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF00698 Acyl transferase domain 1591 1907 8.8E-45 T 11-10-2018 IPR014043 Acyl transferase UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2207 2408 9.0E-22 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF52151 1589 1885 3.92E-58 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF56801 436 993 1.23E-145 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SMART SM01294 2496 2564 0.0021 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF00668 Condensation domain 2581 3015 1.5E-111 T 11-10-2018 IPR001242 Condensation domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Pfam PF00668 Condensation domain 14 456 1.1E-97 T 11-10-2018 IPR001242 Condensation domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 499 895 1.5E-129 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.30.300.30 866 966 6.6E-33 T 11-10-2018 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1230 1246 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.40.47.10 1064 1495 9.8E-156 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.30.559.10 20 387 2.0E-114 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SUPERFAMILY SSF51735 1959 2187 1.44E-12 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 SMART SM00825 Beta-ketoacyl synthase 1070 1495 5.7E-174 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UP12_03530 82976f996bfbdf2d16c8b21c925cf697 3029 Gene3D G3DSA:3.40.366.10 1589 1890 2.5E-129 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Gene3D G3DSA:1.10.150.20 93 158 2.1E-5 T 11-10-2018 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Gene3D G3DSA:3.40.50.300 516 744 3.5E-141 T 11-10-2018 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 SUPERFAMILY SSF52540 197 516 2.24E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 16 753 2.8E-261 T 11-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Pfam PF14490 Helix-hairpin-helix containing domain 157 248 3.6E-30 T 11-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Pfam PF13538 UvrD-like helicase C-terminal domain 680 728 6.0E-18 T 11-10-2018 IPR027785 UvrD-like helicase C-terminal domain UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Gene3D G3DSA:1.10.10.2220 199 296 5.7E-16 T 11-10-2018 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Pfam PF13604 AAA domain 345 553 4.4E-51 T 11-10-2018 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 13 764 29.653 T 11-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 SUPERFAMILY SSF52540 468 741 5.84E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Gene3D G3DSA:2.30.30.940 602 681 3.5E-141 T 11-10-2018 UP12_12025 f80d82b64a0284be745f7d5c3eeaa4b0 794 Gene3D G3DSA:3.40.50.300 337 750 3.5E-141 T 11-10-2018 UP12_01850 b361a702448f67c491d9e01830a0682b 185 SUPERFAMILY SSF52540 13 173 2.82E-22 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_01850 b361a702448f67c491d9e01830a0682b 185 Pfam PF01202 Shikimate kinase 20 177 3.9E-43 T 11-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UP12_01850 b361a702448f67c491d9e01830a0682b 185 Gene3D G3DSA:3.40.50.300 4 178 5.6E-45 T 11-10-2018 UP12_01850 b361a702448f67c491d9e01830a0682b 185 ProSitePatterns PS01128 Shikimate kinase signature. 67 93 - T 11-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UP12_01850 b361a702448f67c491d9e01830a0682b 185 Hamap MF_00109 Shikimate kinase [aroK]. 11 177 25.061 T 11-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 UP12_01850 b361a702448f67c491d9e01830a0682b 185 PRINTS PR01100 Shikimate kinase family signature 106 123 4.5E-17 T 11-10-2018 UP12_01850 b361a702448f67c491d9e01830a0682b 185 PRINTS PR01100 Shikimate kinase family signature 66 74 4.5E-17 T 11-10-2018 UP12_01850 b361a702448f67c491d9e01830a0682b 185 PRINTS PR01100 Shikimate kinase family signature 85 94 4.5E-17 T 11-10-2018 UP12_01850 b361a702448f67c491d9e01830a0682b 185 PRINTS PR01100 Shikimate kinase family signature 14 29 4.5E-17 T 11-10-2018 UP12_01850 b361a702448f67c491d9e01830a0682b 185 PRINTS PR01100 Shikimate kinase family signature 38 51 4.5E-17 T 11-10-2018 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 9.4E-150 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 SUPERFAMILY SSF52210 123 287 1.31E-55 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 Pfam PF00549 CoA-ligase 151 267 9.9E-19 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 Gene3D G3DSA:3.40.50.720 1 123 1.2E-52 T 11-10-2018 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 PIRSF PIRSF001553 1 291 3.6E-135 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 SMART SM00881 4 100 1.6E-35 T 11-10-2018 IPR003781 CoA-binding GO:0048037 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 Gene3D G3DSA:3.40.50.261 124 289 1.2E-72 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.2E-40 T 11-10-2018 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.2E-40 T 11-10-2018 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.2E-40 T 11-10-2018 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.2E-40 T 11-10-2018 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 11-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 11-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 44.021 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 Pfam PF02629 CoA binding domain 6 99 1.6E-31 T 11-10-2018 IPR003781 CoA-binding GO:0048037 UP12_07840 549fdb33b1a1ff80a3d28ba22b1b9890 300 SUPERFAMILY SSF51735 1 122 4.22E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17795 9a0124fb0e476f1d72da581ee5ebcdaf 88 Pfam PF17368 Spore morphogenesis and germination protein YwcE 1 84 4.0E-40 T 11-10-2018 IPR020185 Spore morphogenesis/germination protein YwcE UP12_17795 9a0124fb0e476f1d72da581ee5ebcdaf 88 ProDom PD062384 GERMINATION SPORE TRANSMEMBRANE MEMBRANE MORPHOGENESIS YWCE 1 85 1.0E-31 T 11-10-2018 IPR020185 Spore morphogenesis/germination protein YwcE UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Pfam PF00873 AcrB/AcrD/AcrF family 1 1010 2.6E-161 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:1.20.1640.10 11 499 2.5E-225 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 SUPERFAMILY SSF82693 553 648 5.23E-5 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 SUPERFAMILY SSF82693 138 316 6.98E-7 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:3.30.2090.10 176 267 2.5E-225 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:3.30.70.1430 38 805 2.5E-225 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 SUPERFAMILY SSF82866 287 482 2.35E-34 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 4.6E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 PRINTS PR00702 Acriflavin resistance protein family signature 379 403 4.6E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 PRINTS PR00702 Acriflavin resistance protein family signature 325 348 4.6E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 4.6E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 PRINTS PR00702 Acriflavin resistance protein family signature 457 480 4.6E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 PRINTS PR00702 Acriflavin resistance protein family signature 432 455 4.6E-28 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 SUPERFAMILY SSF82714 180 259 2.35E-5 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:3.30.70.1430 555 656 2.5E-225 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 SUPERFAMILY SSF82866 793 1013 2.09E-44 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:3.30.2090.10 704 797 2.5E-225 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:3.30.70.1320 132 319 2.5E-225 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:3.30.70.1440 657 851 2.5E-225 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 Gene3D G3DSA:1.20.1640.10 500 1008 2.5E-225 T 11-10-2018 UP12_08320 bca259b9503d76d9d96ae0077356c4ad 1014 SUPERFAMILY SSF82693 39 129 1.74E-18 T 11-10-2018 UP12_03940 15045ff44967c76530e09e7604630823 552 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 92 443 1.7E-25 T 11-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UP12_03940 15045ff44967c76530e09e7604630823 552 Gene3D G3DSA:3.40.640.10 103 412 2.5E-56 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_03940 15045ff44967c76530e09e7604630823 552 SUPERFAMILY SSF53383 25 541 4.82E-66 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 SUPERFAMILY SSF51735 122 280 1.9E-52 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.8E-41 T 11-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 1.9E-73 T 11-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 SUPERFAMILY SSF53223 1 121 3.07E-41 T 11-10-2018 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 Gene3D G3DSA:3.40.50.10860 8 276 2.6E-118 T 11-10-2018 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 11-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 Gene3D G3DSA:3.40.50.720 6 258 2.6E-118 T 11-10-2018 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 11-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.1E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.1E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.1E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.1E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.1E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.1E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.1E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_10985 29d989a1fcaa4c7525ad4759a13b1f7d 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 40.343 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 UP12_04400 b038de29df21719b9b54ef1af9c677e0 330 Pfam PF00005 ABC transporter 31 182 2.1E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04400 b038de29df21719b9b54ef1af9c677e0 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 316 1.2E-21 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_04400 b038de29df21719b9b54ef1af9c677e0 330 SUPERFAMILY SSF52540 6 252 8.1E-75 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04400 b038de29df21719b9b54ef1af9c677e0 330 SMART SM00382 40 232 5.2E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04400 b038de29df21719b9b54ef1af9c677e0 330 Gene3D G3DSA:3.40.50.300 3 329 4.2E-99 T 11-10-2018 UP12_04400 b038de29df21719b9b54ef1af9c677e0 330 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_04400 b038de29df21719b9b54ef1af9c677e0 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 296 6.3E-17 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 SUPERFAMILY SSF48179 181 332 4.42E-59 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 39.621 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 Gene3D G3DSA:3.40.50.720 1 184 2.4E-70 T 11-10-2018 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 Gene3D G3DSA:1.10.1040.10 185 341 3.1E-55 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 189 210 - T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 161 7.5E-58 T 11-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 321 1.9E-56 T 11-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 PIRSF PIRSF000114 1 333 3.7E-118 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 SUPERFAMILY SSF51735 3 179 7.11E-62 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 2.6E-50 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 2.6E-50 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 239 256 2.6E-50 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 199 223 2.6E-50 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 2.6E-50 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_10255 5deeecd857d0079d12fe05f45e9c39dd 345 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 2.6E-50 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 UP12_17720 3a9be1ececf71ee52e66a3902649fba2 452 PIRSF PIRSF036492 2 452 1.5E-182 T 11-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 UP12_17720 3a9be1ececf71ee52e66a3902649fba2 452 Pfam PF00171 Aldehyde dehydrogenase family 10 424 7.2E-93 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_17720 3a9be1ececf71ee52e66a3902649fba2 452 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 205 212 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UP12_17720 3a9be1ececf71ee52e66a3902649fba2 452 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 233 244 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UP12_17720 3a9be1ececf71ee52e66a3902649fba2 452 Gene3D G3DSA:3.40.309.10 209 404 9.8E-178 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_17720 3a9be1ececf71ee52e66a3902649fba2 452 SUPERFAMILY SSF53720 6 438 1.96E-128 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_17720 3a9be1ececf71ee52e66a3902649fba2 452 Gene3D G3DSA:3.40.605.10 15 424 9.8E-178 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_15940 c46b96397e9eaae9576d535d0a212275 471 Pfam PF00324 Amino acid permease 16 454 1.4E-129 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_15940 c46b96397e9eaae9576d535d0a212275 471 PIRSF PIRSF006060 1 469 3.7E-80 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_15940 c46b96397e9eaae9576d535d0a212275 471 ProSitePatterns PS00218 Amino acid permeases signature. 41 72 - T 11-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 UP12_15940 c46b96397e9eaae9576d535d0a212275 471 Gene3D G3DSA:1.20.1740.10 7 468 8.5E-71 T 11-10-2018 UP12_16585 5635c0882ebefe15b703566f1944877d 97 Pfam PF10719 Late competence development protein ComFB 4 82 8.8E-16 T 11-10-2018 IPR019657 Late competence development protein ComFB UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Gene3D G3DSA:1.10.287.130 902 977 3.0E-18 T 11-10-2018 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SUPERFAMILY SSF55785 780 898 1.68E-14 T 11-10-2018 IPR035965 PAS domain superfamily UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Pfam PF08448 PAS fold 792 901 8.7E-8 T 11-10-2018 IPR013656 PAS fold-4 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Pfam PF00512 His Kinase A (phospho-acceptor) domain 916 975 1.2E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Pfam PF01339 CheB methylesterase 20 177 6.5E-11 T 11-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Gene3D G3DSA:3.30.450.20 789 901 6.2E-14 T 11-10-2018 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 PRINTS PR00996 Glutamate methyltransferase family signature 302 322 1.5E-21 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 PRINTS PR00996 Glutamate methyltransferase family signature 338 354 1.5E-21 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 PRINTS PR00996 Glutamate methyltransferase family signature 423 446 1.5E-21 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 PRINTS PR00996 Glutamate methyltransferase family signature 404 418 1.5E-21 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Pfam PF01739 CheR methyltransferase, SAM binding domain 269 460 2.2E-52 T 11-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SUPERFAMILY SSF55874 967 1125 6.55E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SMART SM00388 915 978 1.2E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Pfam PF13596 PAS domain 682 773 3.2E-7 T 11-10-2018 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SMART SM00138 199 464 1.9E-54 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Gene3D G3DSA:3.40.50.180 12 193 8.9E-14 T 11-10-2018 IPR035909 Methylesterase CheB, C-terminal UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SUPERFAMILY SSF52738 17 188 8.76E-12 T 11-10-2018 IPR035909 Methylesterase CheB, C-terminal UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Pfam PF13426 PAS domain 501 588 0.47 T 11-10-2018 IPR000014 PAS domain UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Gene3D G3DSA:3.30.565.10 978 1126 4.8E-36 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SMART SM00387 1020 1126 4.0E-23 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SUPERFAMILY SSF47384 911 975 3.34E-14 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 790 907 3.6E-12 T 11-10-2018 IPR000014 PAS domain UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Gene3D G3DSA:3.40.50.150 267 465 1.9E-60 T 11-10-2018 UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1022 1125 8.1E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_04730 0b5386cf94fb224c48b4f915705b0aa3 1126 SUPERFAMILY SSF53335 267 463 1.04E-40 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_03380 2312576885dd6305fa204634401c12e9 189 Gene3D G3DSA:3.40.50.170 1 187 1.2E-72 T 11-10-2018 UP12_03380 2312576885dd6305fa204634401c12e9 189 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 11-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_03380 2312576885dd6305fa204634401c12e9 189 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 30.978 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 UP12_03380 2312576885dd6305fa204634401c12e9 189 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 187 9.5E-74 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 UP12_03380 2312576885dd6305fa204634401c12e9 189 Pfam PF00551 Formyl transferase 2 182 1.5E-60 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_03380 2312576885dd6305fa204634401c12e9 189 SUPERFAMILY SSF53328 2 187 6.41E-59 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_06025 860d7e988886376867008ff89e8f8223 291 SUPERFAMILY SSF53850 90 289 8.15E-42 T 11-10-2018 UP12_06025 860d7e988886376867008ff89e8f8223 291 Pfam PF03466 LysR substrate binding domain 90 286 4.7E-42 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_06025 860d7e988886376867008ff89e8f8223 291 Gene3D G3DSA:1.10.10.10 1 89 2.2E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06025 860d7e988886376867008ff89e8f8223 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.0E-18 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06025 860d7e988886376867008ff89e8f8223 291 Gene3D G3DSA:3.40.190.290 90 289 3.8E-43 T 11-10-2018 UP12_06025 860d7e988886376867008ff89e8f8223 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06025 860d7e988886376867008ff89e8f8223 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06025 860d7e988886376867008ff89e8f8223 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06025 860d7e988886376867008ff89e8f8223 291 SUPERFAMILY SSF46785 1 83 1.36E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09075 9c604ec07293c1a5b052a9793785a5b9 304 Pfam PF00294 pfkB family carbohydrate kinase 11 287 1.4E-50 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB UP12_09075 9c604ec07293c1a5b052a9793785a5b9 304 PIRSF PIRSF000535 1 304 3.3E-79 T 11-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UP12_09075 9c604ec07293c1a5b052a9793785a5b9 304 Gene3D G3DSA:3.40.1190.20 1 304 7.4E-93 T 11-10-2018 IPR029056 Ribokinase-like UP12_09075 9c604ec07293c1a5b052a9793785a5b9 304 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 8.3E-105 T 11-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 UP12_09075 9c604ec07293c1a5b052a9793785a5b9 304 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 9.2E-103 T 11-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UP12_09075 9c604ec07293c1a5b052a9793785a5b9 304 SUPERFAMILY SSF53613 2 302 1.4E-62 T 11-10-2018 IPR029056 Ribokinase-like UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 Gene3D G3DSA:1.10.10.10 1 81 6.4E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 Gene3D G3DSA:3.40.190.290 82 284 1.7E-71 T 11-10-2018 UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 SUPERFAMILY SSF53850 89 284 9.91E-31 T 11-10-2018 UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 SUPERFAMILY SSF46785 1 111 7.26E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.5E-16 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.1E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.1E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.1E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_12795 baaa8fb8902cd5e75e787e2cc01bcfcd 286 Pfam PF03466 LysR substrate binding domain 89 284 6.8E-33 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_08380 e755d15f9194d347cadf5e3c4013472d 157 SMART SM01058 1 109 7.0E-34 T 11-10-2018 IPR003711 CarD-like/TRCF domain UP12_08380 e755d15f9194d347cadf5e3c4013472d 157 Pfam PF02559 CarD-like/TRCF domain 2 108 4.5E-18 T 11-10-2018 IPR003711 CarD-like/TRCF domain UP12_08380 e755d15f9194d347cadf5e3c4013472d 157 Gene3D G3DSA:2.30.30.840 1 60 2.5E-22 T 11-10-2018 UP12_08380 e755d15f9194d347cadf5e3c4013472d 157 Gene3D G3DSA:1.20.58.1290 61 156 3.1E-27 T 11-10-2018 UP12_08380 e755d15f9194d347cadf5e3c4013472d 157 SUPERFAMILY SSF141259 2 65 3.14E-13 T 11-10-2018 IPR036101 CarD-like/TRCF domain superfamily UP12_10835 7134b3a851f592b2c3f54a7d47e8ae87 140 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 8.5E-35 T 11-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 UP12_10835 7134b3a851f592b2c3f54a7d47e8ae87 140 Gene3D G3DSA:3.10.180.10 1 130 4.7E-32 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_10835 7134b3a851f592b2c3f54a7d47e8ae87 140 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 115 7.1E-22 T 11-10-2018 UP12_10835 7134b3a851f592b2c3f54a7d47e8ae87 140 SUPERFAMILY SSF54593 2 133 2.37E-22 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_00715 e3abd6fc1229ec071a601cf264a26341 319 Pfam PF00561 alpha/beta hydrolase fold 30 133 9.6E-13 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_00715 e3abd6fc1229ec071a601cf264a26341 319 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 4.9E-9 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UP12_00715 e3abd6fc1229ec071a601cf264a26341 319 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 32 40 4.9E-9 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UP12_00715 e3abd6fc1229ec071a601cf264a26341 319 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 60 71 4.9E-9 T 11-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 UP12_00715 e3abd6fc1229ec071a601cf264a26341 319 SUPERFAMILY SSF53474 11 305 1.45E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_00715 e3abd6fc1229ec071a601cf264a26341 319 Gene3D G3DSA:3.40.50.1820 8 311 1.2E-40 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_07920 e5a31b574259b11d02e6fedf730760e6 232 Pfam PF03448 MgtE intracellular N domain 155 226 4.7E-9 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain UP12_07920 e5a31b574259b11d02e6fedf730760e6 232 SUPERFAMILY SSF158791 166 217 1.19E-7 T 11-10-2018 UP12_07920 e5a31b574259b11d02e6fedf730760e6 232 Gene3D G3DSA:1.25.60.10 150 229 2.6E-7 T 11-10-2018 IPR038076 MgtE, N-terminal domain superfamily UP12_17005 d10f20120bf7cb04a2828b55fa546d36 279 Pfam PF00460 Flagella basal body rod protein 5 35 1.1E-13 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 UP12_17005 d10f20120bf7cb04a2828b55fa546d36 279 SUPERFAMILY SSF117143 123 236 3.01E-6 T 11-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like UP12_17005 d10f20120bf7cb04a2828b55fa546d36 279 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 198 273 3.5E-16 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain UP12_17005 d10f20120bf7cb04a2828b55fa546d36 279 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site UP12_10855 c5a87dfda05776f9cf7925dc1f0305a3 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 109 3.7E-31 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_10855 c5a87dfda05776f9cf7925dc1f0305a3 218 SUPERFAMILY SSF161098 12 206 7.46E-43 T 11-10-2018 IPR035906 MetI-like superfamily UP12_10855 c5a87dfda05776f9cf7925dc1f0305a3 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 215 2.3E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_10855 c5a87dfda05776f9cf7925dc1f0305a3 218 Gene3D G3DSA:1.10.3720.10 1 217 9.6E-55 T 11-10-2018 IPR035906 MetI-like superfamily UP12_07715 545d69695a051a900b412be55fbf949d 557 Pfam PF13684 Dihydroxyacetone kinase family 240 557 5.2E-125 T 11-10-2018 IPR033470 Uncharacterised protein, DhaK domain UP12_07715 545d69695a051a900b412be55fbf949d 557 Gene3D G3DSA:1.25.40.340 10 179 5.0E-12 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UP12_07715 545d69695a051a900b412be55fbf949d 557 Pfam PF02734 DAK2 domain 36 200 5.7E-42 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UP12_07715 545d69695a051a900b412be55fbf949d 557 SUPERFAMILY SSF101473 4 201 3.27E-45 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UP12_07715 545d69695a051a900b412be55fbf949d 557 SMART SM01120 36 201 1.7E-69 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 UP12_07715 545d69695a051a900b412be55fbf949d 557 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 557 3.6E-212 T 11-10-2018 IPR019986 DAK2 domain-containing protein YloV UP12_07715 545d69695a051a900b412be55fbf949d 557 SMART SM01121 240 557 5.9E-186 T 11-10-2018 IPR033470 Uncharacterised protein, DhaK domain UP12_07695 12f2525f86a7966cfebf8b9172553ca9 214 Gene3D G3DSA:3.40.50.10240 1 214 1.4E-79 T 11-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UP12_07695 12f2525f86a7966cfebf8b9172553ca9 214 SMART SM00983 142 208 9.1E-27 T 11-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UP12_07695 12f2525f86a7966cfebf8b9172553ca9 214 SUPERFAMILY SSF63862 133 213 6.28E-16 T 11-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UP12_07695 12f2525f86a7966cfebf8b9172553ca9 214 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 4 210 4.2E-66 T 11-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UP12_07695 12f2525f86a7966cfebf8b9172553ca9 214 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 23 128 4.9E-20 T 11-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UP12_07695 12f2525f86a7966cfebf8b9172553ca9 214 SUPERFAMILY SSF63999 3 127 1.7E-33 T 11-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UP12_07695 12f2525f86a7966cfebf8b9172553ca9 214 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 144 207 1.1E-17 T 11-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 UP12_10095 53567380d3d62be0c8f8307898d7bcab 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 1.3E-23 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 UP12_10095 53567380d3d62be0c8f8307898d7bcab 290 PIRSF PIRSF006483 2 283 6.3E-99 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_10095 53567380d3d62be0c8f8307898d7bcab 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 10 215 2.3E-64 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_10095 53567380d3d62be0c8f8307898d7bcab 290 Gene3D G3DSA:3.30.70.120 193 268 2.3E-27 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_01410 aed8e703deaff4ea8e69a9fefafb4ec8 294 Pfam PF00480 ROK family 4 283 3.4E-60 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_01410 aed8e703deaff4ea8e69a9fefafb4ec8 294 Gene3D G3DSA:3.30.420.40 1 103 1.1E-27 T 11-10-2018 UP12_01410 aed8e703deaff4ea8e69a9fefafb4ec8 294 ProSitePatterns PS01125 ROK family signature. 130 155 - T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_01410 aed8e703deaff4ea8e69a9fefafb4ec8 294 Gene3D G3DSA:3.30.420.40 104 294 9.6E-56 T 11-10-2018 UP12_01410 aed8e703deaff4ea8e69a9fefafb4ec8 294 SUPERFAMILY SSF53067 1 286 1.51E-46 T 11-10-2018 UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Pfam PF07085 DRTGG domain 76 178 1.1E-28 T 11-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Pfam PF03061 Thioesterase superfamily 354 425 8.9E-7 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Gene3D G3DSA:3.10.580.10 186 314 3.1E-24 T 11-10-2018 UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 58 9.9E-5 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Pfam PF00571 CBS domain 253 307 2.8E-9 T 11-10-2018 IPR000644 CBS domain UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Pfam PF00571 CBS domain 191 244 3.3E-6 T 11-10-2018 IPR000644 CBS domain UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Gene3D G3DSA:3.10.129.10 324 439 3.0E-7 T 11-10-2018 UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 SUPERFAMILY SSF75138 72 185 9.29E-30 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Gene3D G3DSA:1.10.10.10 5 69 9.8E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 Gene3D G3DSA:3.40.1390.20 70 178 1.3E-26 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 SMART SM00116 259 307 6.2E-8 T 11-10-2018 IPR000644 CBS domain UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 SMART SM00116 200 248 3.2 T 11-10-2018 IPR000644 CBS domain UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 SUPERFAMILY SSF46785 5 54 2.92E-6 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 SUPERFAMILY SSF54637 339 433 4.15E-15 T 11-10-2018 IPR029069 HotDog domain superfamily UP12_13160 87c96854c70a185799ac1cdbe666eb88 440 SUPERFAMILY SSF54631 182 307 2.4E-30 T 11-10-2018 UP12_07295 a10bf4982d2bffdaa0faee55819f1f3c 342 SUPERFAMILY SSF54211 229 334 9.86E-21 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_07295 a10bf4982d2bffdaa0faee55819f1f3c 342 Gene3D G3DSA:2.30.42.10 129 205 5.5E-22 T 11-10-2018 UP12_07295 a10bf4982d2bffdaa0faee55819f1f3c 342 SUPERFAMILY SSF50156 129 212 5.65E-15 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_07295 a10bf4982d2bffdaa0faee55819f1f3c 342 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 232 332 8.5E-11 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 UP12_07295 a10bf4982d2bffdaa0faee55819f1f3c 342 Pfam PF13180 PDZ domain 129 196 4.6E-10 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_07295 a10bf4982d2bffdaa0faee55819f1f3c 342 Gene3D G3DSA:3.30.230.10 206 342 4.0E-17 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_07295 a10bf4982d2bffdaa0faee55819f1f3c 342 SMART SM00228 112 187 0.007 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 Pfam PF07690 Major Facilitator Superfamily 14 353 1.2E-23 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 Gene3D G3DSA:1.20.1250.20 1 188 8.4E-16 T 11-10-2018 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 136 157 3.2E-5 T 11-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 72 90 3.2E-5 T 11-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 163 180 3.2E-5 T 11-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 9 31 3.2E-5 T 11-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 PRINTS PR01988 Putative bacilysin exporter bacE signature 297 320 3.2E-5 T 11-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 SUPERFAMILY SSF103473 3 395 1.31E-39 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_11845 45c312ce9b603b2e391984f4a3b92318 405 Gene3D G3DSA:1.20.1250.20 216 397 5.1E-12 T 11-10-2018 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF55048 1529 1589 9.29E-8 T 11-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF00550 Phosphopantetheine attachment site 2311 2374 9.7E-12 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF00550 Phosphopantetheine attachment site 802 865 2.8E-9 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 392 502 3.2E-18 T 11-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1263 1375 1.3E-20 T 11-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:3.40.50.1820 2299 2402 3.1E-23 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:3.30.70.3290 1326 1749 1.6E-135 T 11-10-2018 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF52151 1402 1687 7.06E-66 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF53901 887 1309 5.66E-83 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1144 1261 5.9E-42 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 273 389 3.8E-42 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF51735 1771 1998 5.88E-15 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:3.40.366.10 1403 1705 1.6E-135 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 890 1136 8.7E-66 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 19 265 2.1E-68 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF08659 KR domain 2019 2219 8.9E-42 T 11-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1405 1698 9.7E-90 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SMART SM00825 Beta-ketoacyl synthase 891 1313 1.6E-167 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SMART SM00825 Beta-ketoacyl synthase 20 442 3.1E-170 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1049 1065 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF53901 19 438 2.21E-83 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:3.40.50.720 1750 2281 6.9E-86 T 11-10-2018 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SMART SM00823 Phosphopantetheine attachment site 2309 2378 0.0014 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SMART SM00823 Phosphopantetheine attachment site 800 869 0.028 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF51735 2017 2255 1.59E-30 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:3.40.47.10 885 1311 3.7E-159 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:1.10.1200.10 794 876 1.9E-9 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:3.40.47.10 20 485 8.5E-191 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF47336 797 903 3.53E-15 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF47336 2301 2374 1.83E-18 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Pfam PF00698 Acyl transferase domain 1403 1695 1.2E-48 T 11-10-2018 IPR014043 Acyl transferase UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SUPERFAMILY SSF52151 551 680 4.97E-8 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 Gene3D G3DSA:3.30.70.3050 486 527 8.5E-191 T 11-10-2018 UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 178 194 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2333 2348 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_03545 a7c78bde78bd2f7dcd3bf12af8cd921a 2416 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2019 2222 8.3E-37 T 11-10-2018 UP12_04795 a47666ac0c677ca8810482840a357746 498 SUPERFAMILY SSF53067 5 256 1.38E-99 T 11-10-2018 UP12_04795 a47666ac0c677ca8810482840a357746 498 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 59.737 T 11-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 UP12_04795 a47666ac0c677ca8810482840a357746 498 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_04795 a47666ac0c677ca8810482840a357746 498 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 5.5E-92 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UP12_04795 a47666ac0c677ca8810482840a357746 498 Gene3D G3DSA:3.30.420.40 1 254 2.8E-115 T 11-10-2018 UP12_04795 a47666ac0c677ca8810482840a357746 498 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 495 2.8E-227 T 11-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 UP12_04795 a47666ac0c677ca8810482840a357746 498 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_04795 a47666ac0c677ca8810482840a357746 498 SUPERFAMILY SSF53067 256 495 2.03E-85 T 11-10-2018 UP12_04795 a47666ac0c677ca8810482840a357746 498 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 451 1.2E-64 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UP12_04795 a47666ac0c677ca8810482840a357746 498 Gene3D G3DSA:3.30.420.40 255 498 3.4E-91 T 11-10-2018 UP12_04795 a47666ac0c677ca8810482840a357746 498 PIRSF PIRSF000538 4 498 1.6E-183 T 11-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_17605 0fdad14ff42b5760ec2f88ca59afb4a2 200 Gene3D G3DSA:3.40.190.10 26 111 1.8E-5 T 11-10-2018 UP12_17605 0fdad14ff42b5760ec2f88ca59afb4a2 200 Gene3D G3DSA:3.40.190.10 112 183 1.8E-5 T 11-10-2018 UP12_17605 0fdad14ff42b5760ec2f88ca59afb4a2 200 SUPERFAMILY SSF53850 22 183 8.03E-10 T 11-10-2018 UP12_17600 89c55813e8b141aa637f5a554a7030de 410 Pfam PF07690 Major Facilitator Superfamily 22 334 6.1E-51 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_17600 89c55813e8b141aa637f5a554a7030de 410 SUPERFAMILY SSF103473 6 399 2.88E-72 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_17600 89c55813e8b141aa637f5a554a7030de 410 Gene3D G3DSA:1.20.1250.20 218 407 2.1E-26 T 11-10-2018 UP12_17600 89c55813e8b141aa637f5a554a7030de 410 Gene3D G3DSA:1.20.1250.20 14 217 3.1E-39 T 11-10-2018 UP12_01520 3848dbc3e0f662254a7193bb070ea68b 145 Gene3D G3DSA:1.10.10.10 2 142 2.4E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01520 3848dbc3e0f662254a7193bb070ea68b 145 Pfam PF01047 MarR family 35 92 3.4E-15 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01520 3848dbc3e0f662254a7193bb070ea68b 145 SMART SM00347 27 127 6.2E-24 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01520 3848dbc3e0f662254a7193bb070ea68b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.7E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01520 3848dbc3e0f662254a7193bb070ea68b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 3.7E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01520 3848dbc3e0f662254a7193bb070ea68b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.7E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01520 3848dbc3e0f662254a7193bb070ea68b 145 SUPERFAMILY SSF46785 12 139 2.26E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_17855 f3ee0de6a6bbac4de77eca067de87a4f 46 SUPERFAMILY SSF47406 8 37 2.49E-8 T 11-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 UP12_17855 f3ee0de6a6bbac4de77eca067de87a4f 46 Pfam PF08671 Anti-repressor SinI 10 35 9.9E-12 T 11-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 UP12_19090 5927f2288498b503b536c3498faf92db 79 Gene3D G3DSA:4.10.640.10 3 78 5.7E-30 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 11-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 77 8.3E-36 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 78 21.995 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 SUPERFAMILY SSF46911 6 78 9.02E-30 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 76 3.0E-22 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 1.1E-20 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 1.1E-20 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 1.1E-20 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 1.1E-20 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19090 5927f2288498b503b536c3498faf92db 79 Pfam PF01084 Ribosomal protein S18 23 73 3.9E-27 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 264 3.6E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 264 280 3.6E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 Gene3D G3DSA:1.10.10.60 178 230 1.1E-11 T 11-10-2018 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 Gene3D G3DSA:1.10.10.60 231 286 5.2E-18 T 11-10-2018 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 SUPERFAMILY SSF46689 234 281 2.15E-10 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 SMART SM00342 197 280 2.0E-27 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 SUPERFAMILY SSF51215 3 171 3.27E-18 T 11-10-2018 IPR037923 Transcription regulator HTH-like UP12_05425 1150a5b43d4466d8de08360465f50a49 288 Pfam PF02311 AraC-like ligand binding domain 37 92 5.1E-7 T 11-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 SUPERFAMILY SSF46689 185 231 2.15E-6 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 234 276 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UP12_05425 1150a5b43d4466d8de08360465f50a49 288 Pfam PF12833 Helix-turn-helix domain 203 280 7.7E-20 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_01360 c63ef3d1539c706b973da0cbb1733841 322 Pfam PF12368 Rhodanase C-terminal 222 288 2.7E-13 T 11-10-2018 IPR022111 Rhodanase, C-terminal UP12_01360 c63ef3d1539c706b973da0cbb1733841 322 SUPERFAMILY SSF52821 88 247 2.61E-35 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_01360 c63ef3d1539c706b973da0cbb1733841 322 Gene3D G3DSA:3.40.250.10 102 250 8.6E-45 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_01360 c63ef3d1539c706b973da0cbb1733841 322 SMART SM00450 115 216 2.3E-21 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_01360 c63ef3d1539c706b973da0cbb1733841 322 Hamap MF_00469 UPF0176 protein YceA [yceA]. 3 267 39.817 T 11-10-2018 IPR020936 Uncharacterised protein family UPF0176 UP12_01360 c63ef3d1539c706b973da0cbb1733841 322 Gene3D G3DSA:3.30.70.100 1 97 2.7E-30 T 11-10-2018 UP12_01360 c63ef3d1539c706b973da0cbb1733841 322 Pfam PF00581 Rhodanese-like domain 117 210 4.7E-11 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_08070 2500b5cc617051359d6f5152bffdb889 383 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 381 46.557 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 SUPERFAMILY SSF69055 290 381 7.46E-31 T 11-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 130 9.8E-43 T 11-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 SUPERFAMILY SSF51735 2 148 4.48E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08070 2500b5cc617051359d6f5152bffdb889 383 Gene3D G3DSA:1.10.1740.10 301 383 4.3E-27 T 11-10-2018 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 Gene3D G3DSA:3.40.50.720 1 148 3.6E-48 T 11-10-2018 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 PIRSF PIRSF006205 1 383 1.3E-161 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 SUPERFAMILY SSF55347 125 262 9.81E-61 T 11-10-2018 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 378 3.8E-173 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 Pfam PF13288 DXP reductoisomerase C-terminal domain 259 376 2.5E-42 T 11-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UP12_08070 2500b5cc617051359d6f5152bffdb889 383 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 144 227 2.0E-42 T 11-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 Gene3D G3DSA:3.40.50.720 97 289 1.3E-111 T 11-10-2018 UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 Gene3D G3DSA:3.40.50.720 5 315 1.3E-111 T 11-10-2018 UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 SUPERFAMILY SSF51735 102 289 1.25E-58 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 319 1.2E-25 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 288 1.8E-65 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 177 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 198 220 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UP12_16175 9b14d9c3af0cdae6493b4f5510917ec6 325 SUPERFAMILY SSF52283 2 133 2.76E-32 T 11-10-2018 UP12_00600 906e62a2d6470e02f88d1862724fff99 229 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 11-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UP12_00600 906e62a2d6470e02f88d1862724fff99 229 Gene3D G3DSA:3.90.550.10 2 228 3.0E-82 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_00600 906e62a2d6470e02f88d1862724fff99 229 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 223 42.065 T 11-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UP12_00600 906e62a2d6470e02f88d1862724fff99 229 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 224 3.5E-80 T 11-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UP12_00600 906e62a2d6470e02f88d1862724fff99 229 SUPERFAMILY SSF53448 5 223 9.69E-59 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_00600 906e62a2d6470e02f88d1862724fff99 229 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 5.3E-78 T 11-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 UP12_09105 348995da5c651bee3697636cebded433 475 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UP12_09105 348995da5c651bee3697636cebded433 475 Pfam PF00171 Aldehyde dehydrogenase family 13 469 1.9E-159 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_09105 348995da5c651bee3697636cebded433 475 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UP12_09105 348995da5c651bee3697636cebded433 475 PIRSF PIRSF036492 20 475 1.1E-83 T 11-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 UP12_09105 348995da5c651bee3697636cebded433 475 Gene3D G3DSA:3.40.605.10 9 467 1.5E-161 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_09105 348995da5c651bee3697636cebded433 475 Gene3D G3DSA:3.40.309.10 249 439 1.5E-161 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_09105 348995da5c651bee3697636cebded433 475 SUPERFAMILY SSF53720 5 470 4.32E-153 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_16760 c3d8d435ef38e0b9bf654ea5553e1bee 321 SUPERFAMILY SSF161098 70 308 8.11E-51 T 11-10-2018 IPR035906 MetI-like superfamily UP12_16760 c3d8d435ef38e0b9bf654ea5553e1bee 321 Gene3D G3DSA:1.10.3720.10 66 319 6.7E-65 T 11-10-2018 IPR035906 MetI-like superfamily UP12_16760 c3d8d435ef38e0b9bf654ea5553e1bee 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 309 7.3E-18 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 SUPERFAMILY SSF55190 7 115 9.68E-28 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 SUPERFAMILY SSF47323 431 557 6.34E-36 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 SUPERFAMILY SSF52374 118 448 9.57E-96 T 11-10-2018 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 SMART SM01016 5 95 5.1E-36 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 Hamap MF_00123 Arginine--tRNA ligase [argS]. 10 557 28.195 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 9 94 5.8E-25 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 Pfam PF00750 tRNA synthetases class I (R) 104 400 9.9E-27 T 11-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 SMART SM00836 437 557 1.3E-55 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 Gene3D G3DSA:3.30.1360.70 2 114 1.4E-28 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 Gene3D G3DSA:3.40.50.620 124 431 4.1E-176 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 2.5E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 2.5E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 2.5E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 2.5E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 Gene3D G3DSA:1.10.730.10 432 557 4.1E-176 T 11-10-2018 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 8 557 3.4E-179 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 UP12_17440 2cbffec60907e6a5e29191ca5c0a6b23 557 Pfam PF05746 DALR anticodon binding domain 438 557 1.4E-38 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UP12_15550 065e3fd51c017510488ee6e2e1655699 254 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 139 251 7.5E-36 T 11-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF UP12_15550 065e3fd51c017510488ee6e2e1655699 254 PIRSF PIRSF031509 3 254 3.7E-59 T 11-10-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 UP12_15280 b61f1e9771c176d4e1c5541d49f118da 411 PIRSF PIRSF000524 5 410 1.4E-133 T 11-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 UP12_15280 b61f1e9771c176d4e1c5541d49f118da 411 Gene3D G3DSA:3.40.640.10 23 285 7.8E-144 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_15280 b61f1e9771c176d4e1c5541d49f118da 411 Gene3D G3DSA:3.90.1150.10 10 386 7.8E-144 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_15280 b61f1e9771c176d4e1c5541d49f118da 411 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 209 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UP12_15280 b61f1e9771c176d4e1c5541d49f118da 411 Pfam PF00266 Aminotransferase class-V 39 355 9.8E-33 T 11-10-2018 IPR000192 Aminotransferase class V domain UP12_15280 b61f1e9771c176d4e1c5541d49f118da 411 SUPERFAMILY SSF53383 12 389 9.39E-94 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_03800 89df71f50835deadcdd774d03f83ef29 396 Gene3D G3DSA:1.20.1250.20 14 387 5.8E-53 T 11-10-2018 UP12_03800 89df71f50835deadcdd774d03f83ef29 396 SUPERFAMILY SSF103473 7 388 1.7E-55 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_03800 89df71f50835deadcdd774d03f83ef29 396 Pfam PF07690 Major Facilitator Superfamily 24 332 1.1E-31 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_03800 89df71f50835deadcdd774d03f83ef29 396 PRINTS PR01035 Tetracycline resistance protein signature 143 165 1.5E-12 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_03800 89df71f50835deadcdd774d03f83ef29 396 PRINTS PR01035 Tetracycline resistance protein signature 29 45 1.5E-12 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_03800 89df71f50835deadcdd774d03f83ef29 396 PRINTS PR01035 Tetracycline resistance protein signature 171 191 1.5E-12 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_10945 7a474b01fedae739a633de5621979d36 425 Gene3D G3DSA:2.30.42.10 133 211 7.2E-18 T 11-10-2018 UP12_10945 7a474b01fedae739a633de5621979d36 425 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 3 415 2.6E-175 T 11-10-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B UP12_10945 7a474b01fedae739a633de5621979d36 425 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 105 182 1.0E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_10945 7a474b01fedae739a633de5621979d36 425 SMART SM00228 109 185 1.7E-6 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_10945 7a474b01fedae739a633de5621979d36 425 Pfam PF05580 SpoIVB peptidase S55 202 410 4.0E-87 T 11-10-2018 IPR008763 Peptidase S55, SpoIVB UP12_10945 7a474b01fedae739a633de5621979d36 425 SUPERFAMILY SSF50156 135 214 1.97E-12 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_10945 7a474b01fedae739a633de5621979d36 425 SUPERFAMILY SSF50494 349 409 3.22E-7 T 11-10-2018 IPR009003 Peptidase S1, PA clan UP12_00880 15e483030f9720e28c85b795a000a7c0 289 SMART SM00382 32 223 1.0E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00880 15e483030f9720e28c85b795a000a7c0 289 Gene3D G3DSA:3.40.50.300 1 286 1.3E-77 T 11-10-2018 UP12_00880 15e483030f9720e28c85b795a000a7c0 289 Pfam PF00005 ABC transporter 24 174 9.5E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_00880 15e483030f9720e28c85b795a000a7c0 289 SUPERFAMILY SSF52540 1 240 2.27E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00880 15e483030f9720e28c85b795a000a7c0 289 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 1.4E-122 T 11-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 UP12_00880 15e483030f9720e28c85b795a000a7c0 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 11-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 SUPERFAMILY SSF54919 1 148 1.83E-59 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 Gene3D G3DSA:3.30.70.141 1 148 5.8E-63 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 Pfam PF00334 Nucleoside diphosphate kinase 3 135 2.7E-57 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 36.889 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 5.9E-50 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 5.9E-50 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 5.9E-50 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 5.9E-50 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 5.9E-50 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_10205 073594fcbd40a0406d69c01a161f1fbc 148 SMART SM00562 1 138 3.7E-86 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_02075 30751814c06035136641ae109cd6aa6b 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 118 5.3E-29 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_02075 30751814c06035136641ae109cd6aa6b 230 Gene3D G3DSA:1.10.3720.10 15 227 1.2E-52 T 11-10-2018 IPR035906 MetI-like superfamily UP12_02075 30751814c06035136641ae109cd6aa6b 230 SUPERFAMILY SSF161098 21 226 1.57E-45 T 11-10-2018 IPR035906 MetI-like superfamily UP12_02075 30751814c06035136641ae109cd6aa6b 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 225 1.3E-23 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_16425 4470da2f7776989ea8d9a4dfe6c2f24c 449 Gene3D G3DSA:1.20.1740.10 7 448 9.4E-62 T 11-10-2018 UP12_16425 4470da2f7776989ea8d9a4dfe6c2f24c 449 Pfam PF00324 Amino acid permease 16 440 9.3E-90 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_16425 4470da2f7776989ea8d9a4dfe6c2f24c 449 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 11-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 UP12_16425 4470da2f7776989ea8d9a4dfe6c2f24c 449 PIRSF PIRSF006060 1 446 3.6E-63 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_08305 43eebdad4a0c716d9bb27cf81b43bd7e 264 TIGRFAM TIGR00282 TIGR00282: metallophosphoesterase, MG_246/BB_0505 family 1 264 2.0E-120 T 11-10-2018 IPR005235 Metallophosphoesterase, YmdB-like UP12_08305 43eebdad4a0c716d9bb27cf81b43bd7e 264 PIRSF PIRSF004789 1 262 9.1E-107 T 11-10-2018 IPR005235 Metallophosphoesterase, YmdB-like UP12_08305 43eebdad4a0c716d9bb27cf81b43bd7e 264 SUPERFAMILY SSF56300 1 256 2.04E-90 T 11-10-2018 UP12_08305 43eebdad4a0c716d9bb27cf81b43bd7e 264 Gene3D G3DSA:3.60.21.10 1 264 7.3E-120 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_08305 43eebdad4a0c716d9bb27cf81b43bd7e 264 Pfam PF13277 YmdB-like protein 4 254 2.2E-113 T 11-10-2018 IPR005235 Metallophosphoesterase, YmdB-like UP12_16605 41bef9db0af97e283176a286ad423b01 391 Gene3D G3DSA:3.30.565.10 256 383 1.0E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_16605 41bef9db0af97e283176a286ad423b01 391 SUPERFAMILY SSF55874 271 384 1.57E-19 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_16605 41bef9db0af97e283176a286ad423b01 391 Pfam PF07730 Histidine kinase 180 248 1.6E-16 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UP12_16605 41bef9db0af97e283176a286ad423b01 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 384 4.2E-11 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_16605 41bef9db0af97e283176a286ad423b01 391 PIRSF PIRSF003169 1 388 1.5E-162 T 11-10-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 UP12_16605 41bef9db0af97e283176a286ad423b01 391 SMART SM00387 289 385 2.1E-10 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_16605 41bef9db0af97e283176a286ad423b01 391 Pfam PF05384 Sensor protein DegS 12 170 1.2E-59 T 11-10-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 UP12_18780 16dab810286bc4c95895b4696027a118 100 Pfam PF12840 Helix-turn-helix domain 5 77 7.4E-13 T 11-10-2018 UP12_18780 16dab810286bc4c95895b4696027a118 100 SUPERFAMILY SSF46785 3 97 3.6E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18780 16dab810286bc4c95895b4696027a118 100 Gene3D G3DSA:1.10.10.10 1 100 1.9E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18780 16dab810286bc4c95895b4696027a118 100 SMART SM00418 5 98 1.1E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_02300 7862307ceff9303cddc98ca5f67082ac 203 SUPERFAMILY SSF53335 29 179 7.35E-27 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_02300 7862307ceff9303cddc98ca5f67082ac 203 Gene3D G3DSA:3.40.50.150 18 201 5.7E-27 T 11-10-2018 UP12_02300 7862307ceff9303cddc98ca5f67082ac 203 Pfam PF13649 Methyltransferase domain 47 143 5.7E-15 T 11-10-2018 UP12_17945 01e52ded5a9004e36d7b56d175295abe 210 SMART SM00954 57 180 2.0E-45 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 UP12_17945 01e52ded5a9004e36d7b56d175295abe 210 SUPERFAMILY SSF81301 18 209 1.49E-56 T 11-10-2018 UP12_17945 01e52ded5a9004e36d7b56d175295abe 210 Gene3D G3DSA:1.10.287.860 163 210 5.1E-19 T 11-10-2018 UP12_17945 01e52ded5a9004e36d7b56d175295abe 210 Gene3D G3DSA:3.30.460.10 12 161 7.5E-52 T 11-10-2018 UP12_17945 01e52ded5a9004e36d7b56d175295abe 210 Pfam PF04607 Region found in RelA / SpoT proteins 57 178 5.6E-38 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 11 637 2.1E-265 T 11-10-2018 IPR011927 Stage V sporulation protein D UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 Pfam PF03793 PASTA domain 584 637 3.0E-11 T 11-10-2018 IPR005543 PASTA domain UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 Gene3D G3DSA:3.30.10.20 580 636 6.2E-8 T 11-10-2018 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 200 1.7E-22 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 Gene3D G3DSA:3.40.710.10 283 478 2.4E-111 T 11-10-2018 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 Gene3D G3DSA:3.90.1310.30 49 220 5.1E-45 T 11-10-2018 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 SUPERFAMILY SSF56601 171 565 1.62E-99 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 SMART SM00740 580 638 4.1E-14 T 11-10-2018 IPR005543 PASTA domain UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 Gene3D G3DSA:3.30.450.330 222 560 2.4E-111 T 11-10-2018 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 SUPERFAMILY SSF54184 584 638 8.63E-11 T 11-10-2018 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 SUPERFAMILY SSF56519 52 220 2.22E-43 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UP12_07355 415aefd7dddf6899e65b10f4e31d727f 639 Pfam PF00905 Penicillin binding protein transpeptidase domain 246 556 9.5E-86 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_02360 7f9015c2d1de9a787e847a1ab0bbfa73 360 SUPERFAMILY SSF48208 10 333 1.16E-39 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UP12_02360 7f9015c2d1de9a787e847a1ab0bbfa73 360 Pfam PF01270 Glycosyl hydrolases family 8 44 233 1.4E-8 T 11-10-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UP12_02360 7f9015c2d1de9a787e847a1ab0bbfa73 360 Gene3D G3DSA:1.50.10.10 35 354 1.2E-103 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 Gene3D G3DSA:3.30.390.10 3 127 2.3E-59 T 11-10-2018 IPR029017 Enolase-like, N-terminal UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 Pfam PF03952 Enolase, N-terminal domain 4 134 2.6E-62 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 SUPERFAMILY SSF54826 3 138 7.51E-61 T 11-10-2018 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 PRINTS PR00148 Enolase signature 313 324 2.0E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 PRINTS PR00148 Enolase signature 336 350 2.0E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 PRINTS PR00148 Enolase signature 161 174 2.0E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 PRINTS PR00148 Enolase signature 37 51 2.0E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 PRINTS PR00148 Enolase signature 107 123 2.0E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 PRINTS PR00148 Enolase signature 365 382 2.0E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 2.7E-222 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 SUPERFAMILY SSF51604 139 428 7.36E-131 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 Gene3D G3DSA:3.20.20.120 128 430 5.1E-139 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 SMART SM01192 139 427 5.7E-229 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 Hamap MF_00318 Enolase [eno]. 2 413 46.078 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 ProSitePatterns PS00164 Enolase signature. 336 349 - T 11-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 PIRSF PIRSF001400 1 427 3.6E-197 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 SMART SM01193 4 134 4.0E-100 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15910 f5c2ab659f1b1538eb4bd263bad85262 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 425 3.6E-144 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_01205 0e87e144e2639f5319be927c2ae04240 220 SUPERFAMILY SSF46689 5 76 4.82E-20 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_01205 0e87e144e2639f5319be927c2ae04240 220 Gene3D G3DSA:1.10.357.10 2 201 9.8E-46 T 11-10-2018 UP12_01205 0e87e144e2639f5319be927c2ae04240 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.4E-18 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_01205 0e87e144e2639f5319be927c2ae04240 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 3.5E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_01205 0e87e144e2639f5319be927c2ae04240 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 3.5E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 PIRSF PIRSF006092 1 157 1.6E-52 T 11-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 85 157 4.3E-27 T 11-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 157 2.8E-58 T 11-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 Gene3D G3DSA:1.10.287.180 5 78 1.8E-31 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 Gene3D G3DSA:3.10.50.30 79 157 8.9E-28 T 11-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 157 33.05 T 11-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 2.8E-31 T 11-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 SUPERFAMILY SSF46557 7 79 4.58E-27 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 UP12_11920 78a679a43ab7bc113e5fa3e22efdd9e1 157 SUPERFAMILY SSF54534 83 156 4.05E-22 T 11-10-2018 UP12_11675 bcedd94d87820049b8e39f2f43caf8b2 46 Pfam PF08970 Sporulation inhibitor A 1 44 4.8E-24 T 11-10-2018 IPR015064 Sporulation inhibitor A UP12_11675 bcedd94d87820049b8e39f2f43caf8b2 46 SUPERFAMILY SSF100985 1 44 4.71E-17 T 11-10-2018 IPR036916 Sporulation inhibitor A superfamily UP12_11675 bcedd94d87820049b8e39f2f43caf8b2 46 Gene3D G3DSA:1.10.287.1100 4 37 5.8E-20 T 11-10-2018 IPR036916 Sporulation inhibitor A superfamily UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 Gene3D G3DSA:3.30.70.260 300 363 2.3E-6 T 11-10-2018 UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 Gene3D G3DSA:1.10.3660.10 185 299 5.8E-36 T 11-10-2018 UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 SUPERFAMILY SSF48179 178 286 7.03E-35 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 Pfam PF02153 Prephenate dehydrogenase 20 279 8.5E-92 T 11-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 Pfam PF01842 ACT domain 301 342 4.2E-8 T 11-10-2018 IPR002912 ACT domain UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 SUPERFAMILY SSF55021 294 349 3.82E-8 T 11-10-2018 UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 Gene3D G3DSA:3.40.50.720 3 183 4.5E-52 T 11-10-2018 UP12_10145 9593bfc62aa901b27685adbbe2f2d3c2 371 SUPERFAMILY SSF51735 8 173 7.39E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17715 d79e7a5a15252e1a4c6e0016588318d0 110 Pfam PF17261 Family of unknown function (DUF5327) 2 110 4.2E-26 T 11-10-2018 IPR035218 Protein of unknown function DUF5327 UP12_17715 d79e7a5a15252e1a4c6e0016588318d0 110 ProDom PD705231 YWDI GROUP-SPECIFIC 1 110 3.0E-27 T 11-10-2018 IPR035218 Protein of unknown function DUF5327 UP12_10045 f60328592dd56eaa47f0b54b2c39670a 127 Gene3D G3DSA:2.40.40.20 1 125 7.3E-55 T 11-10-2018 UP12_10045 f60328592dd56eaa47f0b54b2c39670a 127 Pfam PF02261 Aspartate decarboxylase 1 114 2.9E-54 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UP12_10045 f60328592dd56eaa47f0b54b2c39670a 127 SUPERFAMILY SSF50692 1 121 4.1E-50 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UP12_10045 f60328592dd56eaa47f0b54b2c39670a 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 98 8.0E-41 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UP12_10045 f60328592dd56eaa47f0b54b2c39670a 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 1.4E-59 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UP12_10045 f60328592dd56eaa47f0b54b2c39670a 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 73.697 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UP12_10045 f60328592dd56eaa47f0b54b2c39670a 127 PIRSF PIRSF006246 1 126 4.0E-55 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 UP12_14555 32033b65b941f77da37f949cb3e6fb0a 349 Pfam PF04865 Baseplate J-like protein 62 306 1.1E-62 T 11-10-2018 IPR006949 Baseplate protein J-like UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 Pfam PF00199 Catalase 18 407 4.8E-175 T 11-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 PIRSF PIRSF038928 7 501 8.0E-180 T 11-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 Pfam PF06628 Catalase-related immune-responsive 433 495 8.3E-22 T 11-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 ProSitePatterns PS00438 Catalase proximal active site signature. 54 70 - T 11-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 SMART SM01060 18 411 7.7E-257 T 11-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 SUPERFAMILY SSF56634 11 497 7.07E-198 T 11-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 PRINTS PR00067 Catalase signature 336 362 3.7E-68 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 PRINTS PR00067 Catalase signature 31 54 3.7E-68 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 PRINTS PR00067 Catalase signature 99 117 3.7E-68 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 PRINTS PR00067 Catalase signature 139 157 3.7E-68 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 PRINTS PR00067 Catalase signature 304 331 3.7E-68 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 PRINTS PR00067 Catalase signature 120 137 3.7E-68 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 Gene3D G3DSA:2.40.180.10 14 514 3.2E-226 T 11-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 UP12_19060 c04bebe7edbef49f61025f22ceb1ab68 529 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 349 357 - T 11-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_10010 4039b0cd353471781979b0f0e664c31e 904 Gene3D G3DSA:3.40.710.10 327 652 6.7E-210 T 11-10-2018 UP12_10010 4039b0cd353471781979b0f0e664c31e 904 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 94 640 2.6E-177 T 11-10-2018 UP12_10010 4039b0cd353471781979b0f0e664c31e 904 SUPERFAMILY SSF53955 72 286 5.06E-73 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_10010 4039b0cd353471781979b0f0e664c31e 904 SUPERFAMILY SSF56601 241 698 3.02E-107 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_10010 4039b0cd353471781979b0f0e664c31e 904 Pfam PF00905 Penicillin binding protein transpeptidase domain 352 638 3.6E-46 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_10010 4039b0cd353471781979b0f0e664c31e 904 Gene3D G3DSA:1.10.3810.10 94 286 6.7E-210 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_10010 4039b0cd353471781979b0f0e664c31e 904 SUPERFAMILY SSF49265 702 778 2.11E-7 T 11-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 UP12_10010 4039b0cd353471781979b0f0e664c31e 904 Gene3D G3DSA:2.60.40.10 700 794 2.7E-9 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_10010 4039b0cd353471781979b0f0e664c31e 904 Pfam PF00912 Transglycosylase 85 259 4.7E-63 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_10010 4039b0cd353471781979b0f0e664c31e 904 Gene3D G3DSA:3.90.1310.20 79 535 6.7E-210 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 70 95 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 287 313 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 322 341 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 349 369 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 140 162 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 PRINTS PR00173 Glutamate-aspartate symporter signature 222 241 7.0E-35 T 11-10-2018 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 SUPERFAMILY SSF118215 7 396 4.18E-112 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 Gene3D G3DSA:1.10.3860.10 1 413 1.2E-122 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 290 313 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 32 47 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_03080 7fea3005e95671b6a424f8ad6f6efda2 416 Pfam PF00375 Sodium:dicarboxylate symporter family 7 395 1.5E-118 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 Gene3D G3DSA:3.30.565.10 319 477 1.9E-20 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 SMART SM00387 361 476 7.1E-8 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 Gene3D G3DSA:1.20.1480.50 162 258 1.5E-16 T 11-10-2018 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 SUPERFAMILY SSF55874 323 473 3.67E-20 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 SUPERFAMILY SSF158472 201 250 1.7E-8 T 11-10-2018 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 Pfam PF00672 HAMP domain 201 246 4.9E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 SMART SM00304 199 252 2.4E-6 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 9.1E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 9.1E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 451 9.1E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 Pfam PF06580 Histidine kinase 267 346 1.3E-23 T 11-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 UP12_16775 a1ab7bccfba99346a86aad678c24d403 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 474 3.6E-10 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_16335 d8d4257d08f15b770817d12dbda8170f 241 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 120 138 - T 11-10-2018 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 UP12_16335 d8d4257d08f15b770817d12dbda8170f 241 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 239 1.9E-91 T 11-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 UP12_16335 d8d4257d08f15b770817d12dbda8170f 241 Gene3D G3DSA:3.40.50.1360 1 241 6.6E-96 T 11-10-2018 UP12_16335 d8d4257d08f15b770817d12dbda8170f 241 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 241 41.81 T 11-10-2018 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|Reactome: R-HSA-70171 UP12_16335 d8d4257d08f15b770817d12dbda8170f 241 SUPERFAMILY SSF100950 1 238 1.31E-89 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_16335 d8d4257d08f15b770817d12dbda8170f 241 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 227 9.4E-20 T 11-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 UP12_12100 49f77dfa73eb17d73d2440c0d54a1612 162 Pfam PF02080 TrkA-C domain 90 158 4.2E-17 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UP12_12100 49f77dfa73eb17d73d2440c0d54a1612 162 Gene3D G3DSA:3.30.70.1450 85 160 4.0E-20 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_12100 49f77dfa73eb17d73d2440c0d54a1612 162 SUPERFAMILY SSF116726 84 157 1.44E-17 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_12100 49f77dfa73eb17d73d2440c0d54a1612 162 PIRSF PIRSF005028 1 162 2.7E-57 T 11-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT UP12_09645 f4b8e3e4e90c0e0fe3fb92e3b157d2e2 202 Gene3D G3DSA:1.20.144.10 110 201 5.8E-25 T 11-10-2018 UP12_09645 f4b8e3e4e90c0e0fe3fb92e3b157d2e2 202 Gene3D G3DSA:1.20.144.10 1 109 1.5E-7 T 11-10-2018 UP12_09645 f4b8e3e4e90c0e0fe3fb92e3b157d2e2 202 Pfam PF01569 PAP2 superfamily 80 195 1.2E-24 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UP12_09645 f4b8e3e4e90c0e0fe3fb92e3b157d2e2 202 SMART SM00014 76 190 6.1E-25 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UP12_09645 f4b8e3e4e90c0e0fe3fb92e3b157d2e2 202 SUPERFAMILY SSF48317 4 193 7.06E-35 T 11-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily UP12_09740 76393890a8b5fcacad1dbbc12fdaf664 253 SUPERFAMILY SSF52266 37 247 6.2E-36 T 11-10-2018 UP12_09740 76393890a8b5fcacad1dbbc12fdaf664 253 Gene3D G3DSA:3.40.50.1110 19 248 8.2E-36 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_09740 76393890a8b5fcacad1dbbc12fdaf664 253 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 44 235 2.2E-28 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain UP12_16100 ac278fbf8cad011a6e4992e607fb9bee 256 SMART SM00382 37 222 1.0E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16100 ac278fbf8cad011a6e4992e607fb9bee 256 SUPERFAMILY SSF52540 21 236 1.54E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16100 ac278fbf8cad011a6e4992e607fb9bee 256 Gene3D G3DSA:3.40.50.300 15 256 7.2E-70 T 11-10-2018 UP12_16100 ac278fbf8cad011a6e4992e607fb9bee 256 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16100 ac278fbf8cad011a6e4992e607fb9bee 256 Pfam PF00005 ABC transporter 29 172 3.7E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_12950 7fc91b553028eb856baab4c8a6ef02f2 88 Pfam PF06961 Protein of unknown function (DUF1294) 13 67 3.3E-22 T 11-10-2018 IPR010718 Protein of unknown function DUF1294 UP12_08840 f8f479ef8ab62e720afabb26b681bfd2 150 SUPERFAMILY SSF54593 9 146 5.51E-19 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_08840 f8f479ef8ab62e720afabb26b681bfd2 150 Gene3D G3DSA:3.10.180.10 1 144 1.6E-22 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_08840 f8f479ef8ab62e720afabb26b681bfd2 150 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 116 1.6E-10 T 11-10-2018 UP12_14415 93c85305f854fca7dabbb1f928c8d32a 430 SUPERFAMILY SSF52540 162 415 3.64E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_14415 93c85305f854fca7dabbb1f928c8d32a 430 Gene3D G3DSA:1.10.860.10 1 136 8.2E-31 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal UP12_14415 93c85305f854fca7dabbb1f928c8d32a 430 Gene3D G3DSA:3.40.50.300 143 429 2.8E-104 T 11-10-2018 UP12_14415 93c85305f854fca7dabbb1f928c8d32a 430 Pfam PF00772 DnaB-like helicase N terminal domain 4 100 2.6E-19 T 11-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 UP12_14415 93c85305f854fca7dabbb1f928c8d32a 430 Pfam PF03796 DnaB-like helicase C terminal domain 164 421 7.5E-95 T 11-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 UP12_14415 93c85305f854fca7dabbb1f928c8d32a 430 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 5 423 2.4E-127 T 11-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 UP12_14415 93c85305f854fca7dabbb1f928c8d32a 430 SUPERFAMILY SSF48024 5 107 1.19E-19 T 11-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 UP12_01680 5bf786efe744eac18c1194f854f03c23 422 SMART SM00116 347 395 8.7E-4 T 11-10-2018 IPR000644 CBS domain UP12_01680 5bf786efe744eac18c1194f854f03c23 422 SMART SM00116 287 335 0.021 T 11-10-2018 IPR000644 CBS domain UP12_01680 5bf786efe744eac18c1194f854f03c23 422 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_01680 5bf786efe744eac18c1194f854f03c23 422 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 41 397 1.1E-172 T 11-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 UP12_01680 5bf786efe744eac18c1194f854f03c23 422 Gene3D G3DSA:3.40.50.300 3 274 4.1E-73 T 11-10-2018 UP12_01680 5bf786efe744eac18c1194f854f03c23 422 SMART SM00382 58 247 4.7E-22 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_01680 5bf786efe744eac18c1194f854f03c23 422 SUPERFAMILY SSF54631 279 397 9.47E-16 T 11-10-2018 UP12_01680 5bf786efe744eac18c1194f854f03c23 422 Pfam PF00005 ABC transporter 50 197 4.6E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_01680 5bf786efe744eac18c1194f854f03c23 422 SUPERFAMILY SSF52540 45 275 3.49E-77 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_01680 5bf786efe744eac18c1194f854f03c23 422 Gene3D G3DSA:3.10.580.10 283 396 2.1E-15 T 11-10-2018 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 SUPERFAMILY SSF48452 401 510 1.33E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 Gene3D G3DSA:1.25.40.10 382 511 2.0E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 Pfam PF14559 Tetratricopeptide repeat 441 504 3.1E-6 T 11-10-2018 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 Pfam PF01694 Rhomboid family 224 359 2.5E-40 T 11-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 SMART SM00028 463 496 10.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 SMART SM00028 429 462 2.4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 SUPERFAMILY SSF144091 180 362 9.55E-48 T 11-10-2018 UP12_11260 5e7ba5182192d686389aa60ea4484708 512 Gene3D G3DSA:1.20.1540.10 176 368 1.3E-52 T 11-10-2018 IPR035952 Rhomboid-like superfamily UP12_00340 81941e24f48346805d711881c29265e4 1177 Gene3D G3DSA:3.90.1150.50 1020 1177 4.9E-42 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain UP12_00340 81941e24f48346805d711881c29265e4 1177 Gene3D G3DSA:2.30.30.840 503 561 2.7E-246 T 11-10-2018 UP12_00340 81941e24f48346805d711881c29265e4 1177 Pfam PF02559 CarD-like/TRCF domain 500 595 6.8E-32 T 11-10-2018 IPR003711 CarD-like/TRCF domain UP12_00340 81941e24f48346805d711881c29265e4 1177 SUPERFAMILY SSF52540 377 490 1.54E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00340 81941e24f48346805d711881c29265e4 1177 SMART SM00487 620 810 2.2E-32 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_00340 81941e24f48346805d711881c29265e4 1177 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 42 1147 28.776 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 UP12_00340 81941e24f48346805d711881c29265e4 1177 SMART SM01058 499 596 7.3E-52 T 11-10-2018 IPR003711 CarD-like/TRCF domain UP12_00340 81941e24f48346805d711881c29265e4 1177 SUPERFAMILY SSF52540 543 803 6.97E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00340 81941e24f48346805d711881c29265e4 1177 Gene3D G3DSA:3.40.50.300 498 1008 2.7E-246 T 11-10-2018 UP12_00340 81941e24f48346805d711881c29265e4 1177 Pfam PF00270 DEAD/DEAH box helicase 625 784 3.5E-16 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_00340 81941e24f48346805d711881c29265e4 1177 SUPERFAMILY SSF52540 802 1009 4.63E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00340 81941e24f48346805d711881c29265e4 1177 Gene3D G3DSA:3.40.50.11180 35 325 1.7E-68 T 11-10-2018 UP12_00340 81941e24f48346805d711881c29265e4 1177 SUPERFAMILY SSF141259 491 568 1.31E-26 T 11-10-2018 IPR036101 CarD-like/TRCF domain superfamily UP12_00340 81941e24f48346805d711881c29265e4 1177 Gene3D G3DSA:3.40.50.300 562 801 2.7E-246 T 11-10-2018 UP12_00340 81941e24f48346805d711881c29265e4 1177 SMART SM00490 846 930 3.3E-19 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_00340 81941e24f48346805d711881c29265e4 1177 Pfam PF03461 TRCF domain 1025 1117 1.9E-25 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 UP12_00340 81941e24f48346805d711881c29265e4 1177 Pfam PF00271 Helicase conserved C-terminal domain 828 929 7.2E-17 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_00340 81941e24f48346805d711881c29265e4 1177 SUPERFAMILY SSF143517 1011 1169 3.01E-36 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain UP12_00340 81941e24f48346805d711881c29265e4 1177 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 157 1098 0.0 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 UP12_00340 81941e24f48346805d711881c29265e4 1177 Gene3D G3DSA:3.30.2060.10 140 225 1.7E-68 T 11-10-2018 UP12_00340 81941e24f48346805d711881c29265e4 1177 SMART SM00982 1024 1124 5.3E-37 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 UP12_00340 81941e24f48346805d711881c29265e4 1177 SUPERFAMILY SSF52540 14 367 2.04E-91 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00995 4c47fc85137301bb29b0c4a2f26e0805 415 Gene3D G3DSA:3.40.50.12170 40 415 3.4E-159 T 11-10-2018 UP12_00995 4c47fc85137301bb29b0c4a2f26e0805 415 PIRSF PIRSF016719 1 415 7.3E-183 T 11-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 UP12_00995 4c47fc85137301bb29b0c4a2f26e0805 415 Pfam PF07075 Protein of unknown function (DUF1343) 58 415 8.7E-155 T 11-10-2018 IPR008302 Uncharacterised conserved protein UCP016719 UP12_00995 4c47fc85137301bb29b0c4a2f26e0805 415 Gene3D G3DSA:3.90.1150.140 253 400 3.4E-159 T 11-10-2018 UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 Gene3D G3DSA:2.40.50.940 222 357 4.8E-13 T 11-10-2018 UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 Pfam PF08402 TOBE domain 280 357 6.3E-14 T 11-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 355 9.9E-118 T 11-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 SMART SM00382 28 211 2.4E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 SUPERFAMILY SSF52540 4 241 2.8E-89 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 SUPERFAMILY SSF50331 237 358 3.51E-11 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 Gene3D G3DSA:3.40.50.300 4 221 5.6E-68 T 11-10-2018 UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 Pfam PF00005 ABC transporter 19 161 5.4E-36 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 Gene3D G3DSA:2.40.50.140 287 349 4.8E-13 T 11-10-2018 UP12_01985 34b58d7cc979d3065daaba715e73fa14 363 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_03015 24d6c3ef6ef7eaf658fd91fde3bc69c7 350 SUPERFAMILY SSF51679 1 340 2.71E-82 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_03015 24d6c3ef6ef7eaf658fd91fde3bc69c7 350 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 2 339 5.9E-161 T 11-10-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative UP12_03015 24d6c3ef6ef7eaf658fd91fde3bc69c7 350 Gene3D G3DSA:3.20.20.30 1 348 1.2E-91 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_03015 24d6c3ef6ef7eaf658fd91fde3bc69c7 350 Pfam PF00296 Luciferase-like monooxygenase 8 305 4.6E-47 T 11-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UP12_15265 ed0a990d6fd28790a3a06c9a75ba8d3d 384 Pfam PF13556 PucR C-terminal helix-turn-helix domain 317 375 1.2E-21 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_15265 ed0a990d6fd28790a3a06c9a75ba8d3d 384 Gene3D G3DSA:1.10.10.2840 253 379 7.5E-19 T 11-10-2018 UP12_17915 2be66966591d7d81daadcfd6a80a04e9 393 SUPERFAMILY SSF88697 1 70 9.2E-19 T 11-10-2018 IPR015947 PUA-like superfamily UP12_17915 2be66966591d7d81daadcfd6a80a04e9 393 Gene3D G3DSA:3.30.750.80 71 177 2.5E-36 T 11-10-2018 UP12_17915 2be66966591d7d81daadcfd6a80a04e9 393 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 101 345 8.8E-34 T 11-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 UP12_17915 2be66966591d7d81daadcfd6a80a04e9 393 SMART SM00359 2 86 1.8E-5 T 11-10-2018 IPR002478 PUA domain GO:0003723 UP12_17915 2be66966591d7d81daadcfd6a80a04e9 393 SUPERFAMILY SSF53335 77 390 1.86E-66 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_17915 2be66966591d7d81daadcfd6a80a04e9 393 Gene3D G3DSA:2.30.130.10 1 69 1.4E-22 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 UP12_17915 2be66966591d7d81daadcfd6a80a04e9 393 Gene3D G3DSA:3.40.50.150 179 393 1.0E-59 T 11-10-2018 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Gene3D G3DSA:3.30.10.20 500 565 3.6E-17 T 11-10-2018 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Gene3D G3DSA:2.60.40.2560 569 647 3.1E-16 T 11-10-2018 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 SMART SM00220 11 268 1.8E-70 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Pfam PF03793 PASTA domain 501 561 3.1E-14 T 11-10-2018 IPR005543 PASTA domain UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Pfam PF03793 PASTA domain 362 424 1.4E-12 T 11-10-2018 IPR005543 PASTA domain UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Pfam PF03793 PASTA domain 432 494 1.3E-15 T 11-10-2018 IPR005543 PASTA domain UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Gene3D G3DSA:1.10.510.10 92 276 2.7E-53 T 11-10-2018 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Gene3D G3DSA:3.30.200.20 1 90 7.4E-34 T 11-10-2018 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Gene3D G3DSA:3.30.10.20 359 427 1.2E-15 T 11-10-2018 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 SMART SM00740 427 495 2.4E-16 T 11-10-2018 IPR005543 PASTA domain UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 SMART SM00740 358 426 5.5E-13 T 11-10-2018 IPR005543 PASTA domain UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 SMART SM00740 496 562 9.3E-18 T 11-10-2018 IPR005543 PASTA domain UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Pfam PF00069 Protein kinase domain 11 258 8.9E-55 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 SUPERFAMILY SSF56112 8 268 1.05E-82 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 Gene3D G3DSA:3.30.10.20 430 497 7.9E-18 T 11-10-2018 UP12_07680 e68cd83e2e3adae1af46a667a58fb342 651 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 2.0E-24 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 2.0E-24 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.0E-24 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 2.0E-24 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 Pfam PF00557 Metallopeptidase family M24 12 239 9.9E-57 T 11-10-2018 IPR000994 Peptidase M24 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 Gene3D G3DSA:3.90.230.10 1 248 9.2E-109 T 11-10-2018 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 43.546 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.6E-104 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_00835 2078fc86eadc2084c8ceec5328df4451 248 SUPERFAMILY SSF55920 1 247 1.28E-90 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like UP12_01940 895596155224ad09493330a0332c4b3a 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 4.3E-11 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_01940 895596155224ad09493330a0332c4b3a 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 4.3E-11 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_01940 895596155224ad09493330a0332c4b3a 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 4.3E-11 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_01940 895596155224ad09493330a0332c4b3a 138 SMART SM00344 2 107 9.9E-20 T 11-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UP12_01940 895596155224ad09493330a0332c4b3a 138 Gene3D G3DSA:3.30.70.920 52 137 7.6E-10 T 11-10-2018 UP12_01940 895596155224ad09493330a0332c4b3a 138 SUPERFAMILY SSF54909 63 136 6.17E-9 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_01940 895596155224ad09493330a0332c4b3a 138 Pfam PF01037 Lrp/AsnC ligand binding domain 69 133 1.2E-6 T 11-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UP12_01940 895596155224ad09493330a0332c4b3a 138 SUPERFAMILY SSF46785 1 58 6.28E-13 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_01940 895596155224ad09493330a0332c4b3a 138 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 2.6E-14 T 11-10-2018 UP12_01940 895596155224ad09493330a0332c4b3a 138 Gene3D G3DSA:1.10.10.10 1 51 1.3E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06970 ae41d926491a84a30329858164341ffc 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UP12_06970 ae41d926491a84a30329858164341ffc 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 6.3E-107 T 11-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 UP12_06970 ae41d926491a84a30329858164341ffc 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UP12_06970 ae41d926491a84a30329858164341ffc 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 1.3E-108 T 11-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UP12_06970 ae41d926491a84a30329858164341ffc 303 SUPERFAMILY SSF53613 1 282 4.99E-67 T 11-10-2018 IPR029056 Ribokinase-like UP12_06970 ae41d926491a84a30329858164341ffc 303 Gene3D G3DSA:3.40.1190.20 1 303 9.4E-108 T 11-10-2018 IPR029056 Ribokinase-like UP12_06970 ae41d926491a84a30329858164341ffc 303 Pfam PF00294 pfkB family carbohydrate kinase 13 285 1.8E-58 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB UP12_06970 ae41d926491a84a30329858164341ffc 303 PIRSF PIRSF000535 1 303 2.1E-104 T 11-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 UP12_13555 c8a1ca92c5d831961b75c12dafe8936e 540 Pfam PF01943 Polysaccharide biosynthesis protein 5 320 6.2E-63 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 UP12_13555 c8a1ca92c5d831961b75c12dafe8936e 540 PIRSF PIRSF038958 1 540 1.1E-190 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type UP12_13555 c8a1ca92c5d831961b75c12dafe8936e 540 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 374 522 1.0E-27 T 11-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain UP12_09565 5dc985581ac030956a2a30f4e66bc47d 221 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 7.5E-27 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UP12_09565 5dc985581ac030956a2a30f4e66bc47d 221 SUPERFAMILY SSF102588 2 194 6.41E-48 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UP12_09565 5dc985581ac030956a2a30f4e66bc47d 221 TIGRFAM TIGR04000 thiol_BshB2: bacillithiol biosynthesis deacetylase BshB2 3 219 6.6E-108 T 11-10-2018 IPR023841 Bacillithiol biosynthesis deacetylase BshB2 UP12_09565 5dc985581ac030956a2a30f4e66bc47d 221 Gene3D G3DSA:3.40.50.10320 1 213 6.4E-46 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UP12_07600 4abdc49c85fce8763881e73ea1062706 251 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UP12_07600 4abdc49c85fce8763881e73ea1062706 251 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UP12_07600 4abdc49c85fce8763881e73ea1062706 251 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 6.1E-104 T 11-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UP12_07600 4abdc49c85fce8763881e73ea1062706 251 SUPERFAMILY SSF53790 1 247 1.15E-87 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 UP12_07600 4abdc49c85fce8763881e73ea1062706 251 Gene3D G3DSA:3.30.950.10 118 250 3.5E-47 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 UP12_07600 4abdc49c85fce8763881e73ea1062706 251 Gene3D G3DSA:3.40.1010.10 1 117 6.7E-49 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 UP12_07600 4abdc49c85fce8763881e73ea1062706 251 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 214 3.3E-52 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 SUPERFAMILY SSF53155 186 269 1.1E-11 T 11-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 SUPERFAMILY SSF57884 2 86 4.18E-31 T 11-10-2018 IPR035451 Ada-like domain superfamily UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 Gene3D G3DSA:3.40.10.10 2 75 1.3E-25 T 11-10-2018 IPR035451 Ada-like domain superfamily UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 315 321 - T 11-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 Gene3D G3DSA:3.30.160.70 183 260 2.2E-8 T 11-10-2018 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 SMART SM00342 98 179 8.4E-11 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 266 345 4.4E-30 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 SUPERFAMILY SSF46767 264 345 2.88E-29 T 11-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 Gene3D G3DSA:1.10.10.60 81 182 2.1E-13 T 11-10-2018 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 Pfam PF02805 Metal binding domain of Ada 11 73 6.9E-27 T 11-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 PIRSF PIRSF000409 1 347 1.5E-136 T 11-10-2018 IPR016221 Bifunctional regulatory protein Ada UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 Gene3D G3DSA:1.10.10.10 262 346 9.7E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 265 344 9.6E-32 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 UP12_06350 d3ff2c6dc4f85d2eaf659cb1c15e52e6 347 Pfam PF12833 Helix-turn-helix domain 105 179 3.4E-13 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_05730 5d3aa67286dea684b9bc706be88c2ead 221 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 9 182 2.6E-65 T 11-10-2018 IPR022301 Integral membrane protein YjbE UP12_05730 5d3aa67286dea684b9bc706be88c2ead 221 Pfam PF03741 Integral membrane protein TerC family 11 181 3.2E-43 T 11-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 UP12_01565 daa448a3a19a884d8a4a5dcfcbf4fe96 361 SUPERFAMILY SSF103642 4 24 6.05E-7 T 11-10-2018 UP12_01565 daa448a3a19a884d8a4a5dcfcbf4fe96 361 Gene3D G3DSA:3.10.450.50 2 25 2.9E-5 T 11-10-2018 UP12_01565 daa448a3a19a884d8a4a5dcfcbf4fe96 361 Pfam PF02810 SEC-C motif 6 24 7.4E-10 T 11-10-2018 IPR004027 SEC-C motif UP12_01565 daa448a3a19a884d8a4a5dcfcbf4fe96 361 Pfam PF05225 helix-turn-helix, Psq domain 308 350 4.7E-6 T 11-10-2018 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SMART SM00091 264 330 1.8E-6 T 11-10-2018 IPR000014 PAS domain UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SUPERFAMILY SSF158472 205 254 1.27E-9 T 11-10-2018 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 542 2.0E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 587 600 2.0E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 581 2.0E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 556 2.0E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 490 601 1.6E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Gene3D G3DSA:3.30.450.20 32 183 6.3E-35 T 11-10-2018 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 263 375 5.2E-6 T 11-10-2018 IPR000014 PAS domain UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Gene3D G3DSA:3.30.565.10 452 602 8.5E-52 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SMART SM00387 489 603 1.4E-44 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Pfam PF00512 His Kinase A (phospho-acceptor) domain 378 443 2.0E-18 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Pfam PF00672 HAMP domain 205 253 5.1E-12 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SUPERFAMILY SSF55785 251 369 2.97E-10 T 11-10-2018 IPR035965 PAS domain superfamily UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Gene3D G3DSA:3.30.450.20 275 368 4.3E-21 T 11-10-2018 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Pfam PF13426 PAS domain 275 370 1.6E-6 T 11-10-2018 IPR000014 PAS domain UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SUPERFAMILY SSF55874 433 601 4.85E-49 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Gene3D G3DSA:1.10.287.130 203 274 4.1E-9 T 11-10-2018 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 Gene3D G3DSA:1.10.287.130 369 448 4.0E-28 T 11-10-2018 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SMART SM00304 205 257 1.0E-12 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SUPERFAMILY SSF47384 363 444 5.69E-20 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_18890 de71b862675b57bc9aec95a0d4d58989 612 SMART SM00388 377 444 1.1E-20 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_00765 eded161d85b802607252c9bb258702a6 66 SUPERFAMILY SSF46561 1 63 2.62E-24 T 11-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00765 eded161d85b802607252c9bb258702a6 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 11-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00765 eded161d85b802607252c9bb258702a6 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 5.9E-25 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00765 eded161d85b802607252c9bb258702a6 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.254 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00765 eded161d85b802607252c9bb258702a6 66 Gene3D G3DSA:1.10.287.310 1 66 5.7E-31 T 11-10-2018 UP12_00765 eded161d85b802607252c9bb258702a6 66 Pfam PF00831 Ribosomal L29 protein 4 60 5.5E-27 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00300 f439727e04f8d400795ff01945d89bd4 277 Pfam PF00156 Phosphoribosyl transferase domain 108 261 3.3E-23 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UP12_00300 f439727e04f8d400795ff01945d89bd4 277 SUPERFAMILY SSF53271 93 264 6.08E-41 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_00300 f439727e04f8d400795ff01945d89bd4 277 Gene3D G3DSA:3.40.50.2020 75 274 2.9E-61 T 11-10-2018 UP12_00300 f439727e04f8d400795ff01945d89bd4 277 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 269 4.9E-130 T 11-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 UP12_00300 f439727e04f8d400795ff01945d89bd4 277 Gene3D G3DSA:1.10.10.10 1 73 1.1E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_00300 f439727e04f8d400795ff01945d89bd4 277 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 1.5E-30 T 11-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 UP12_00300 f439727e04f8d400795ff01945d89bd4 277 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 74 2.0E-30 T 11-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 UP12_00300 f439727e04f8d400795ff01945d89bd4 277 SUPERFAMILY SSF46785 2 73 5.17E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18685 d15abbdad7dfc91425b98bdee2e37d37 300 SUPERFAMILY SSF51735 113 295 1.25E-32 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_18685 d15abbdad7dfc91425b98bdee2e37d37 300 Gene3D G3DSA:3.40.50.720 114 268 2.4E-87 T 11-10-2018 UP12_18685 d15abbdad7dfc91425b98bdee2e37d37 300 Gene3D G3DSA:3.40.50.10860 17 284 2.4E-87 T 11-10-2018 UP12_18685 d15abbdad7dfc91425b98bdee2e37d37 300 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 13 296 31.486 T 11-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UP12_18685 d15abbdad7dfc91425b98bdee2e37d37 300 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 18 100 2.5E-23 T 11-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UP12_18685 d15abbdad7dfc91425b98bdee2e37d37 300 SUPERFAMILY SSF53223 7 112 5.58E-32 T 11-10-2018 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 Gene3D G3DSA:3.40.190.10 8 184 2.0E-51 T 11-10-2018 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 PIRSF PIRSF001500 1 288 4.8E-69 T 11-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 233 240 - T 11-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 Pfam PF01842 ACT domain 214 261 1.1E-6 T 11-10-2018 IPR002912 ACT domain UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 Gene3D G3DSA:3.40.190.10 87 176 2.0E-51 T 11-10-2018 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 Pfam PF00800 Prephenate dehydratase 6 188 8.5E-56 T 11-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 Gene3D G3DSA:3.30.70.260 197 290 3.3E-26 T 11-10-2018 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 SUPERFAMILY SSF55021 196 284 1.06E-23 T 11-10-2018 UP12_12220 57c93d54670b367eb0fb5f00e275fc95 292 SUPERFAMILY SSF53850 5 189 2.33E-52 T 11-10-2018 UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 SUPERFAMILY SSF47413 4 58 9.38E-13 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 Gene3D G3DSA:3.40.50.2300 76 321 3.5E-36 T 11-10-2018 UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 Gene3D G3DSA:3.40.50.2300 154 290 3.5E-36 T 11-10-2018 UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 SUPERFAMILY SSF53822 71 314 3.0E-34 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.9E-15 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 Pfam PF13377 Periplasmic binding protein-like domain 163 330 1.7E-34 T 11-10-2018 UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 Gene3D G3DSA:1.10.260.40 1 60 1.9E-16 T 11-10-2018 UP12_18510 f41f3ddf369f2b36dc9b3b634a3f3711 331 SMART SM00354 2 69 2.9E-10 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_10305 d5d75dadef5172e77db2d9ee9ebcbd6a 449 Pfam PF14620 YpeB sporulation 13 372 8.6E-133 T 11-10-2018 IPR014239 Spore germination YpeB GO:0009847 UP12_10305 d5d75dadef5172e77db2d9ee9ebcbd6a 449 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 439 5.5E-154 T 11-10-2018 IPR014239 Spore germination YpeB GO:0009847 UP12_10305 d5d75dadef5172e77db2d9ee9ebcbd6a 449 Pfam PF03413 Peptidase propeptide and YPEB domain 376 433 1.3E-4 T 11-10-2018 IPR025711 PepSY domain UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 Pfam PF00375 Sodium:dicarboxylate symporter family 3 396 3.7E-136 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 1 21 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 214 233 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 352 372 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 47 67 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 6.4E-57 T 11-10-2018 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 SUPERFAMILY SSF118215 3 398 5.23E-126 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_02460 6230eea965fedffd62fae56e00bd5f76 413 Gene3D G3DSA:1.10.3860.10 1 410 3.1E-144 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_15830 ce597116a3e31ebf729f0ee2e460ac82 134 SUPERFAMILY SSF47413 1 66 2.04E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_15830 ce597116a3e31ebf729f0ee2e460ac82 134 SMART SM00530 7 63 7.6E-13 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_15830 ce597116a3e31ebf729f0ee2e460ac82 134 Pfam PF13560 Helix-turn-helix domain 4 61 7.3E-14 T 11-10-2018 UP12_15830 ce597116a3e31ebf729f0ee2e460ac82 134 Gene3D G3DSA:1.10.260.40 4 133 4.1E-17 T 11-10-2018 UP12_08010 0d739ada105765deecadabbd4115da79 675 Pfam PF01584 CheW-like domain 548 674 8.6E-27 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_08010 0d739ada105765deecadabbd4115da79 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 540 1.8E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_08010 0d739ada105765deecadabbd4115da79 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 521 1.8E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_08010 0d739ada105765deecadabbd4115da79 675 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 1.8E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_08010 0d739ada105765deecadabbd4115da79 675 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 296 354 9.8E-14 T 11-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 UP12_08010 0d739ada105765deecadabbd4115da79 675 SMART SM00073 3 100 1.2E-37 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 UP12_08010 0d739ada105765deecadabbd4115da79 675 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 403 542 3.9E-15 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_08010 0d739ada105765deecadabbd4115da79 675 Gene3D G3DSA:1.20.120.160 3 135 5.0E-40 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 UP12_08010 0d739ada105765deecadabbd4115da79 675 SMART SM00387 400 543 2.2E-23 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_08010 0d739ada105765deecadabbd4115da79 675 SUPERFAMILY SSF47226 3 112 5.23E-33 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 UP12_08010 0d739ada105765deecadabbd4115da79 675 Pfam PF01627 Hpt domain 5 99 1.4E-20 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 UP12_08010 0d739ada105765deecadabbd4115da79 675 Gene3D G3DSA:2.40.50.180 566 629 1.2E-38 T 11-10-2018 UP12_08010 0d739ada105765deecadabbd4115da79 675 SUPERFAMILY SSF55052 162 245 5.49E-24 T 11-10-2018 IPR035891 CheY-binding domain of CheA UP12_08010 0d739ada105765deecadabbd4115da79 675 Gene3D G3DSA:2.30.30.40 543 669 1.2E-38 T 11-10-2018 UP12_08010 0d739ada105765deecadabbd4115da79 675 SUPERFAMILY SSF47384 296 356 5.49E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_08010 0d739ada105765deecadabbd4115da79 675 Pfam PF07194 P2 response regulator binding domain 165 245 2.2E-24 T 11-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 UP12_08010 0d739ada105765deecadabbd4115da79 675 Gene3D G3DSA:1.10.287.560 295 355 2.1E-19 T 11-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 UP12_08010 0d739ada105765deecadabbd4115da79 675 Gene3D G3DSA:3.30.70.1110 162 246 1.7E-27 T 11-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily UP12_08010 0d739ada105765deecadabbd4115da79 675 SMART SM01231 295 355 1.1E-18 T 11-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 UP12_08010 0d739ada105765deecadabbd4115da79 675 SUPERFAMILY SSF50341 542 674 1.83E-33 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 UP12_08010 0d739ada105765deecadabbd4115da79 675 SUPERFAMILY SSF55874 357 541 1.07E-40 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_08010 0d739ada105765deecadabbd4115da79 675 SMART SM00260 535 674 2.7E-46 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_08010 0d739ada105765deecadabbd4115da79 675 Gene3D G3DSA:3.30.565.10 356 542 1.5E-58 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13710 0d47d92d3d3f48c9acefc29a2037bc14 321 Pfam PF04055 Radical SAM superfamily 52 214 2.4E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_13710 0d47d92d3d3f48c9acefc29a2037bc14 321 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 15 314 5.5E-140 T 11-10-2018 IPR005911 Protein YhcC-like GO:0051536 UP12_13710 0d47d92d3d3f48c9acefc29a2037bc14 321 Pfam PF16199 Radical_SAM C-terminal domain 220 303 2.8E-26 T 11-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 UP12_13710 0d47d92d3d3f48c9acefc29a2037bc14 321 SUPERFAMILY SSF102114 5 314 1.1E-56 T 11-10-2018 UP12_13710 0d47d92d3d3f48c9acefc29a2037bc14 321 SMART SM00729 32 259 1.1E-44 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_13710 0d47d92d3d3f48c9acefc29a2037bc14 321 Gene3D G3DSA:3.80.30.20 50 257 7.1E-15 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UP12_16785 5795eef526afef865009281948f05422 151 Pfam PF00583 Acetyltransferase (GNAT) family 39 129 4.8E-11 T 11-10-2018 IPR000182 GNAT domain UP12_16785 5795eef526afef865009281948f05422 151 SUPERFAMILY SSF55729 9 151 4.97E-22 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_16785 5795eef526afef865009281948f05422 151 Gene3D G3DSA:3.40.630.30 2 151 2.0E-39 T 11-10-2018 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 Gene3D G3DSA:3.90.110.10 171 442 2.7E-105 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 Gene3D G3DSA:3.40.50.720 1 170 1.0E-73 T 11-10-2018 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 SUPERFAMILY SSF51735 4 168 3.15E-58 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 172 - T 11-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 197 412 3.7E-51 T 11-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 SUPERFAMILY SSF56327 173 439 4.86E-98 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 8.6E-55 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 8.6E-55 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 193 205 8.6E-55 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 8.6E-55 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 8.6E-55 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 8.6E-55 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 167 178 8.6E-55 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_17985 d233de65ceafd2a34a04f50ec5ee9d9d 442 Pfam PF02056 Family 4 glycosyl hydrolase 6 187 3.5E-76 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 PIRSF PIRSF000382 3 762 0.0 T 11-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 SUPERFAMILY SSF51726 6 381 1.7E-91 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 6 310 1.5E-120 T 11-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 430 752 1.3E-155 T 11-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 9 757 0.0 T 11-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 4 757 33.986 T 11-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 Gene3D G3DSA:3.20.20.210 8 523 0.0 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 Gene3D G3DSA:3.20.20.210 388 755 0.0 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_06415 7ca6ccab81cd24f58b5dcd00b41ddf77 762 SUPERFAMILY SSF51726 397 756 1.28E-114 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 SUPERFAMILY SSF53649 4 509 3.83E-75 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 5 509 2.0E-210 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 50.112 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 PIRSF PIRSF001492 1 511 8.5E-205 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 Pfam PF01676 Metalloenzyme superfamily 4 499 7.1E-77 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 SUPERFAMILY SSF64158 77 310 6.28E-92 T 11-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 299 9.3E-85 T 11-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 Gene3D G3DSA:3.40.720.10 5 509 1.1E-231 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_15915 2f53af46df819c43c6c21f2cd3eb20f8 511 Gene3D G3DSA:3.40.1450.10 77 312 1.1E-231 T 11-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 UP12_11885 5b3859c6883c289c2c286d3504101de0 382 Gene3D G3DSA:3.90.1150.10 246 381 8.7E-58 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_11885 5b3859c6883c289c2c286d3504101de0 382 SUPERFAMILY SSF53383 17 378 2.13E-122 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_11885 5b3859c6883c289c2c286d3504101de0 382 Gene3D G3DSA:3.40.640.10 3 245 8.8E-93 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_11885 5b3859c6883c289c2c286d3504101de0 382 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 1.6E-163 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_11885 5b3859c6883c289c2c286d3504101de0 382 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_11885 5b3859c6883c289c2c286d3504101de0 382 PIRSF PIRSF001434 1 380 3.2E-150 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 11-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 Gene3D G3DSA:3.90.930.12 1 82 1.0E-34 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 Pfam PF00347 Ribosomal protein L6 90 164 3.6E-20 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 Pfam PF00347 Ribosomal protein L6 11 82 1.4E-23 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 PIRSF PIRSF002162 1 177 2.3E-50 T 11-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.3E-77 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 5.5E-34 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 5.5E-34 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 5.5E-34 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 SUPERFAMILY SSF56053 1 82 3.84E-30 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 SUPERFAMILY SSF56053 83 177 6.04E-34 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.961 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 UP12_00800 3fee31cd81643910ec73ee8edf1efcf6 178 Gene3D G3DSA:3.90.930.12 83 178 7.9E-39 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 61 74 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 SUPERFAMILY SSF88659 109 184 9.59E-18 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 220 246 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 Pfam PF04542 Sigma-70 region 2 37 104 8.4E-18 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 PRINTS PR00046 Major sigma-70 factor signature 235 246 2.6E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 PRINTS PR00046 Major sigma-70 factor signature 220 235 2.6E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 PRINTS PR00046 Major sigma-70 factor signature 203 215 2.6E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 PRINTS PR00046 Major sigma-70 factor signature 85 93 2.6E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 PRINTS PR00046 Major sigma-70 factor signature 61 74 2.6E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 Gene3D G3DSA:1.10.601.10 2 104 2.7E-29 T 11-10-2018 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 PIRSF PIRSF000770 3 255 8.3E-37 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 SUPERFAMILY SSF88946 12 105 2.22E-34 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 249 2.5E-36 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 Pfam PF04545 Sigma-70, region 4 199 246 9.5E-15 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 Gene3D G3DSA:1.10.10.10 105 160 6.2E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 22 249 4.7E-114 T 11-10-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 Pfam PF04539 Sigma-70 region 3 115 183 9.9E-14 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 30 250 1.1E-88 T 11-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 Gene3D G3DSA:1.10.10.10 179 254 1.1E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10550 3d0e0291877835d8a08fa50c6ada4fa1 255 SUPERFAMILY SSF88659 171 250 6.92E-17 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_12925 1d2fd227aa58dd0af4afd0144401d8a1 247 Gene3D G3DSA:3.40.1280.10 99 247 1.8E-50 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UP12_12925 1d2fd227aa58dd0af4afd0144401d8a1 247 Gene3D G3DSA:3.30.1330.30 3 96 1.0E-25 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_12925 1d2fd227aa58dd0af4afd0144401d8a1 247 SUPERFAMILY SSF55315 2 95 3.18E-23 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_12925 1d2fd227aa58dd0af4afd0144401d8a1 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 93 1.2E-7 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UP12_12925 1d2fd227aa58dd0af4afd0144401d8a1 247 SMART SM00967 31 98 3.3E-11 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UP12_12925 1d2fd227aa58dd0af4afd0144401d8a1 247 Pfam PF00588 SpoU rRNA Methylase family 106 243 5.6E-36 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UP12_12925 1d2fd227aa58dd0af4afd0144401d8a1 247 SUPERFAMILY SSF75217 95 246 5.23E-42 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases UP12_00860 02f28bd133043544b45bbad98217afb8 131 Pfam PF00411 Ribosomal protein S11 21 130 6.4E-52 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UP12_00860 02f28bd133043544b45bbad98217afb8 131 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 5 131 34.407 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UP12_00860 02f28bd133043544b45bbad98217afb8 131 ProSitePatterns PS00054 Ribosomal protein S11 signature. 99 121 - T 11-10-2018 IPR018102 Ribosomal S11, conserved site UP12_00860 02f28bd133043544b45bbad98217afb8 131 Gene3D G3DSA:3.30.420.80 3 131 9.1E-54 T 11-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00860 02f28bd133043544b45bbad98217afb8 131 SUPERFAMILY SSF53137 16 131 2.81E-49 T 11-10-2018 UP12_00860 02f28bd133043544b45bbad98217afb8 131 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 12 128 5.8E-58 T 11-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00860 02f28bd133043544b45bbad98217afb8 131 PIRSF PIRSF002131 1 131 2.2E-53 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 UP12_12175 9170cb829c79fd36036e34477277d8bb 586 Pfam PF13667 ThiC-associated domain 17 93 1.5E-30 T 11-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UP12_12175 9170cb829c79fd36036e34477277d8bb 586 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 135 559 3.3E-225 T 11-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UP12_12175 9170cb829c79fd36036e34477277d8bb 586 Pfam PF01964 Radical SAM ThiC family 136 556 2.0E-206 T 11-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UP12_12175 9170cb829c79fd36036e34477277d8bb 586 Gene3D G3DSA:3.20.20.540 179 492 4.3E-157 T 11-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UP12_12175 9170cb829c79fd36036e34477277d8bb 586 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 135 561 100.235 T 11-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 UP12_14890 26d7d003cba7e9f2f1ad90bbe64a9417 360 SUPERFAMILY SSF53822 54 265 3.53E-12 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_14890 26d7d003cba7e9f2f1ad90bbe64a9417 360 Gene3D G3DSA:3.40.50.2300 147 346 5.5E-110 T 11-10-2018 UP12_14890 26d7d003cba7e9f2f1ad90bbe64a9417 360 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 41 351 2.9E-96 T 11-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 UP12_14890 26d7d003cba7e9f2f1ad90bbe64a9417 360 Gene3D G3DSA:3.40.50.2300 43 313 5.5E-110 T 11-10-2018 UP12_15860 447a12b21547752516cff24ab8f6b81f 382 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_15860 447a12b21547752516cff24ab8f6b81f 382 Gene3D G3DSA:3.10.580.10 247 372 2.1E-34 T 11-10-2018 UP12_15860 447a12b21547752516cff24ab8f6b81f 382 SUPERFAMILY SSF52540 1 240 1.32E-79 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15860 447a12b21547752516cff24ab8f6b81f 382 Gene3D G3DSA:3.40.50.300 1 240 2.5E-76 T 11-10-2018 UP12_15860 447a12b21547752516cff24ab8f6b81f 382 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 12 371 2.5E-173 T 11-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 UP12_15860 447a12b21547752516cff24ab8f6b81f 382 Pfam PF00571 CBS domain 311 364 3.0E-6 T 11-10-2018 IPR000644 CBS domain UP12_15860 447a12b21547752516cff24ab8f6b81f 382 Pfam PF00571 CBS domain 251 298 6.2E-9 T 11-10-2018 IPR000644 CBS domain UP12_15860 447a12b21547752516cff24ab8f6b81f 382 SUPERFAMILY SSF54631 250 369 1.94E-24 T 11-10-2018 UP12_15860 447a12b21547752516cff24ab8f6b81f 382 Pfam PF00005 ABC transporter 18 163 6.0E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15860 447a12b21547752516cff24ab8f6b81f 382 SMART SM00382 27 213 4.2E-21 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15860 447a12b21547752516cff24ab8f6b81f 382 SMART SM00116 318 366 2.3E-9 T 11-10-2018 IPR000644 CBS domain UP12_15860 447a12b21547752516cff24ab8f6b81f 382 SMART SM00116 258 306 3.0E-6 T 11-10-2018 IPR000644 CBS domain UP12_05775 307d83a186453bfd28b440727862d4e0 192 Gene3D G3DSA:2.40.320.10 1 189 5.8E-52 T 11-10-2018 UP12_05775 307d83a186453bfd28b440727862d4e0 192 Pfam PF01928 CYTH domain 4 183 4.8E-29 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 UP12_05775 307d83a186453bfd28b440727862d4e0 192 SMART SM01118 4 189 1.8E-22 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 UP12_05775 307d83a186453bfd28b440727862d4e0 192 SUPERFAMILY SSF55154 5 186 1.41E-29 T 11-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 UP12_05775 307d83a186453bfd28b440727862d4e0 192 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 35 85 0.005 T 11-10-2018 UP12_05775 307d83a186453bfd28b440727862d4e0 192 PIRSF PIRSF012526 1 190 1.2E-66 T 11-10-2018 IPR009195 Uncharacterised protein family YjbK UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 Pfam PF06445 GyrI-like small molecule binding domain 121 269 9.0E-10 T 11-10-2018 IPR029442 GyrI-like small molecule binding domain UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 SMART SM00422 2 72 4.7E-13 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 SMART SM00871 120 270 2.5E-13 T 11-10-2018 IPR010499 Bacterial transcription activator, effector binding UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 Gene3D G3DSA:1.10.1660.10 1 120 8.9E-23 T 11-10-2018 UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 Gene3D G3DSA:3.20.80.10 121 272 7.3E-14 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 SUPERFAMILY SSF46955 2 108 2.97E-23 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 SUPERFAMILY SSF55136 121 269 1.49E-10 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_04105 a5dcd100b65e03a71ec580d5fef54cce 275 Pfam PF13411 MerR HTH family regulatory protein 2 71 1.9E-12 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 Gene3D G3DSA:3.40.50.300 1 238 8.1E-62 T 11-10-2018 UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 SUPERFAMILY SSF52540 3 220 1.02E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 SUPERFAMILY SSF52540 266 479 8.88E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 Gene3D G3DSA:3.40.50.300 239 489 3.2E-42 T 11-10-2018 UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 SMART SM00382 27 224 6.3E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 SMART SM00382 276 470 2.1E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 ProSitePatterns PS00211 ABC transporters family signature. 394 408 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 Pfam PF00005 ABC transporter 18 168 5.3E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16900 d6b87e21ed0df8aca31820479a99f963 493 Pfam PF00005 ABC transporter 268 421 7.9E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 Pfam PF00989 PAS fold 78 188 1.2E-13 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 SUPERFAMILY SSF55785 83 194 2.44E-20 T 11-10-2018 IPR035965 PAS domain superfamily UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 Gene3D G3DSA:1.10.287.130 198 276 1.2E-15 T 11-10-2018 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 SMART SM00388 214 277 1.2E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 SMART SM00387 320 426 3.0E-33 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 SUPERFAMILY SSF55874 267 426 1.44E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 SMART SM00086 149 191 8.5E-5 T 11-10-2018 IPR001610 PAC motif UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 SMART SM00091 78 146 2.8E-9 T 11-10-2018 IPR000014 PAS domain UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 77 198 1.3E-17 T 11-10-2018 IPR000014 PAS domain UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 SUPERFAMILY SSF47384 202 275 1.51E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 Gene3D G3DSA:3.30.565.10 277 435 2.5E-45 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 Gene3D G3DSA:3.30.450.20 73 194 1.4E-23 T 11-10-2018 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 275 3.9E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_07010 d827d05866e2d90cd482144a95d80eb8 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 423 2.3E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PIRSF PIRSF000532 1 319 4.0E-126 T 11-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 1.4E-90 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 Gene3D G3DSA:3.40.50.450 3 279 7.5E-124 T 11-10-2018 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 Gene3D G3DSA:3.40.50.460 142 251 7.5E-124 T 11-10-2018 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 SUPERFAMILY SSF53784 1 314 2.75E-122 T 11-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 8.9E-144 T 11-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 Pfam PF00365 Phosphofructokinase 3 275 6.4E-116 T 11-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 11-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 UP12_13110 222ca8be31b144b0cfdaaf9557c8ee38 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 49.702 T 11-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 Gene3D G3DSA:2.10.70.100 149 195 3.2E-10 T 11-10-2018 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 Gene3D G3DSA:3.30.450.20 65 143 4.2E-10 T 11-10-2018 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 SUPERFAMILY SSF55785 98 195 4.36E-14 T 11-10-2018 IPR035965 PAS domain superfamily UP12_18445 dea4f811d7f14c409546c68fb161562d 504 SUPERFAMILY SSF55785 235 334 8.72E-17 T 11-10-2018 IPR035965 PAS domain superfamily UP12_18445 dea4f811d7f14c409546c68fb161562d 504 Gene3D G3DSA:1.10.287.950 327 504 1.0E-38 T 11-10-2018 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 123 201 2.5E-6 T 11-10-2018 IPR000014 PAS domain UP12_18445 dea4f811d7f14c409546c68fb161562d 504 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 238 338 7.9E-8 T 11-10-2018 IPR000014 PAS domain UP12_18445 dea4f811d7f14c409546c68fb161562d 504 Gene3D G3DSA:3.30.450.20 199 326 6.2E-25 T 11-10-2018 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 SMART SM00086 291 333 1.7E-6 T 11-10-2018 IPR001610 PAC motif UP12_18445 dea4f811d7f14c409546c68fb161562d 504 SMART SM00086 152 194 6.6E-5 T 11-10-2018 IPR001610 PAC motif UP12_18445 dea4f811d7f14c409546c68fb161562d 504 SUPERFAMILY SSF58104 330 502 5.89E-46 T 11-10-2018 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 SMART SM00283 328 504 4.0E-5 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 386 495 1.1E-28 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 Pfam PF08447 PAS fold 97 187 9.8E-22 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 UP12_18445 dea4f811d7f14c409546c68fb161562d 504 Pfam PF08447 PAS fold 237 327 4.5E-23 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 Pfam PF00672 HAMP domain 209 257 7.8E-8 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 Pfam PF17202 Single cache domain 3 80 183 5.9E-31 T 11-10-2018 IPR033463 Single cache domain 3 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 Gene3D G3DSA:1.20.1480.50 171 265 1.0E-9 T 11-10-2018 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 336 517 4.4E-44 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 SMART SM00304 208 260 5.6E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 SUPERFAMILY SSF103190 72 183 6.02E-10 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 SUPERFAMILY SSF58104 228 563 3.66E-65 T 11-10-2018 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 SMART SM00283 275 564 1.5E-75 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_01955 3317e2a4ba020ae8ffb91d6fdcdfcf13 565 Gene3D G3DSA:1.10.287.950 297 564 8.6E-60 T 11-10-2018 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 SUPERFAMILY SSF56014 146 344 1.57E-58 T 11-10-2018 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 SUPERFAMILY SSF55124 346 422 3.6E-22 T 11-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 17 560 2.6E-282 T 11-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 Gene3D G3DSA:3.30.413.10 427 568 3.5E-37 T 11-10-2018 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 PRINTS PR00397 Sirohaem Fe-binding site signature 479 497 2.0E-8 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 PRINTS PR00397 Sirohaem Fe-binding site signature 431 449 2.0E-8 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 SUPERFAMILY SSF56014 429 561 7.07E-35 T 11-10-2018 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 8 571 57.486 T 11-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 430 559 7.5E-4 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 SUPERFAMILY SSF55124 13 145 2.45E-33 T 11-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 172 328 9.2E-48 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 354 417 4.3E-13 T 11-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 75 131 1.9E-14 T 11-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09115 892d5f9a96b7b189a8fe4a02dbd2138a 572 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 479 495 - T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 Pfam PF02743 Cache domain 40 281 1.9E-12 T 11-10-2018 IPR033479 Double Cache domain 1 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 SMART SM00342 677 760 5.2E-29 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 SUPERFAMILY SSF46689 713 762 1.25E-10 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 Gene3D G3DSA:3.30.450.20 186 296 5.0E-6 T 11-10-2018 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 SUPERFAMILY SSF46689 664 710 2.06E-7 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 Gene3D G3DSA:1.10.10.60 658 709 1.8E-16 T 11-10-2018 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 Gene3D G3DSA:1.10.10.60 710 764 1.5E-14 T 11-10-2018 UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 SUPERFAMILY SSF103190 201 257 3.3E-5 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_13615 0f7d302726e5ed3c9ccbac66b78ab644 766 Pfam PF12833 Helix-turn-helix domain 683 761 3.3E-19 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 Gene3D G3DSA:3.90.1150.170 63 483 1.9E-133 T 11-10-2018 UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 SUPERFAMILY SSF53383 20 486 6.19E-125 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 Gene3D G3DSA:3.40.640.10 117 369 1.9E-133 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 408 427 7.8E-5 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 364 379 7.8E-5 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 64 83 7.8E-5 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 149 169 7.8E-5 T 11-10-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 UP12_05455 41082f4c20f87456dbe84bcb1286a1a4 498 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 63 427 6.9E-64 T 11-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 Gene3D G3DSA:3.40.50.850 1 211 8.3E-76 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 PIRSF PIRSF001111 1 295 8.4E-131 T 11-10-2018 IPR016291 Isochorismatase GO:0008908 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 Pfam PF00857 Isochorismatase family 32 205 5.9E-37 T 11-10-2018 IPR000868 Isochorismatase-like GO:0003824 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 SUPERFAMILY SSF47336 219 288 5.37E-9 T 11-10-2018 IPR036736 ACP-like superfamily UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 PRINTS PR01398 Isochorismatase signature 112 134 4.3E-47 T 11-10-2018 IPR016291 Isochorismatase GO:0008908 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 PRINTS PR01398 Isochorismatase signature 168 186 4.3E-47 T 11-10-2018 IPR016291 Isochorismatase GO:0008908 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 PRINTS PR01398 Isochorismatase signature 186 203 4.3E-47 T 11-10-2018 IPR016291 Isochorismatase GO:0008908 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 PRINTS PR01398 Isochorismatase signature 2 14 4.3E-47 T 11-10-2018 IPR016291 Isochorismatase GO:0008908 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 PRINTS PR01398 Isochorismatase signature 80 99 4.3E-47 T 11-10-2018 IPR016291 Isochorismatase GO:0008908 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 PRINTS PR01398 Isochorismatase signature 63 80 4.3E-47 T 11-10-2018 IPR016291 Isochorismatase GO:0008908 UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 Gene3D G3DSA:1.10.1200.10 219 290 1.1E-22 T 11-10-2018 IPR036736 ACP-like superfamily UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 Pfam PF00550 Phosphopantetheine attachment site 223 282 2.9E-7 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_18990 370ab9e0846d1ecbff758ddf5fcf6f86 301 SUPERFAMILY SSF52499 1 214 2.49E-61 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_08275 f9d2aa5e75422626574b378a8d52bea0 263 PIRSF PIRSF021288 1 262 1.3E-145 T 11-10-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain UP12_08275 f9d2aa5e75422626574b378a8d52bea0 263 SUPERFAMILY SSF55021 6 73 7.08E-7 T 11-10-2018 UP12_08275 f9d2aa5e75422626574b378a8d52bea0 263 Pfam PF11868 Protein of unknown function (DUF3388) 72 261 2.4E-106 T 11-10-2018 IPR024514 Domain of unknown function DUF3388 UP12_17000 980835333e71461c1038f30ee3814bf7 272 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 156 254 1.4E-20 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G UP12_17000 980835333e71461c1038f30ee3814bf7 272 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 5 143 5.6E-22 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G UP12_17000 980835333e71461c1038f30ee3814bf7 272 Pfam PF00460 Flagella basal body rod protein 12 35 1.1E-7 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 UP12_17000 980835333e71461c1038f30ee3814bf7 272 SUPERFAMILY SSF117143 105 233 4.97E-13 T 11-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like UP12_17000 980835333e71461c1038f30ee3814bf7 272 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 193 269 7.3E-21 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 Gene3D G3DSA:1.20.140.10 235 380 3.8E-56 T 11-10-2018 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 5.1E-24 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 1.3E-52 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.1E-35 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 Gene3D G3DSA:1.10.540.10 1 119 1.3E-42 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 SUPERFAMILY SSF47203 230 379 4.35E-59 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 PIRSF PIRSF016578 3 380 3.1E-27 T 11-10-2018 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 SUPERFAMILY SSF56645 1 243 1.44E-79 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 Gene3D G3DSA:2.40.110.10 122 234 8.5E-39 T 11-10-2018 UP12_09155 97fc3dd961c2a332d2f1ce70168506da 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_17050 22e4d38e275634ead5732864eb4d9c27 246 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_17050 22e4d38e275634ead5732864eb4d9c27 246 SUPERFAMILY SSF52540 7 241 1.06E-80 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17050 22e4d38e275634ead5732864eb4d9c27 246 Pfam PF00005 ABC transporter 23 171 1.8E-36 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17050 22e4d38e275634ead5732864eb4d9c27 246 Gene3D G3DSA:3.40.50.300 3 245 8.0E-79 T 11-10-2018 UP12_17050 22e4d38e275634ead5732864eb4d9c27 246 PIRSF PIRSF039085 4 246 7.8E-118 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UP12_17050 22e4d38e275634ead5732864eb4d9c27 246 SMART SM00382 32 219 1.6E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_09735 54b9241d86124767bd99b5a9f67e29af 188 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 3 184 1.3E-60 T 11-10-2018 IPR018672 Protein of unknown function DUF2140 UP12_14710 67b2270422f3dbb81acbddfb8dd9f844 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 118 8.6E-25 T 11-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UP12_14710 67b2270422f3dbb81acbddfb8dd9f844 327 Gene3D G3DSA:3.30.360.10 135 327 1.1E-62 T 11-10-2018 UP12_14710 67b2270422f3dbb81acbddfb8dd9f844 327 SUPERFAMILY SSF55347 126 291 2.29E-32 T 11-10-2018 UP12_14710 67b2270422f3dbb81acbddfb8dd9f844 327 SUPERFAMILY SSF51735 2 151 1.15E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_14710 67b2270422f3dbb81acbddfb8dd9f844 327 Gene3D G3DSA:3.40.50.720 1 134 3.1E-35 T 11-10-2018 UP12_16160 70ed2f3876d825dbf5f0601858faef4b 109 Gene3D G3DSA:1.10.287.1080 1 102 2.4E-27 T 11-10-2018 UP12_16160 70ed2f3876d825dbf5f0601858faef4b 109 SUPERFAMILY SSF101386 1 104 2.29E-24 T 11-10-2018 UP12_16160 70ed2f3876d825dbf5f0601858faef4b 109 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 102 2.4E-10 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UP12_16160 70ed2f3876d825dbf5f0601858faef4b 109 PIRSF PIRSF036521 1 107 2.6E-51 T 11-10-2018 IPR011411 NTP Pyrophosphohydrolase MazG-related UP12_09930 f26e5729a7511bf7701f1cffa7aae4f2 645 SUPERFAMILY SSF52540 52 623 9.63E-19 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09930 f26e5729a7511bf7701f1cffa7aae4f2 645 Gene3D G3DSA:3.40.50.300 465 638 1.3E-24 T 11-10-2018 UP12_09930 f26e5729a7511bf7701f1cffa7aae4f2 645 Gene3D G3DSA:3.40.50.300 37 316 1.4E-27 T 11-10-2018 UP12_09930 f26e5729a7511bf7701f1cffa7aae4f2 645 Pfam PF13307 Helicase C-terminal domain 489 637 2.3E-26 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UP12_09930 f26e5729a7511bf7701f1cffa7aae4f2 645 SMART SM00491 500 626 4.2E-7 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UP12_00730 6258ad7cb02f4d90a54489c71d6f902b 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 37.738 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00730 6258ad7cb02f4d90a54489c71d6f902b 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 2.7E-83 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00730 6258ad7cb02f4d90a54489c71d6f902b 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.1E-72 T 11-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 UP12_00730 6258ad7cb02f4d90a54489c71d6f902b 207 SUPERFAMILY SSF52166 1 206 2.88E-84 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00730 6258ad7cb02f4d90a54489c71d6f902b 207 Gene3D G3DSA:3.40.1370.10 3 207 4.8E-82 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 UP12_13715 e7c0d41a8b34d9caac9949ab77e3b646 191 Gene3D G3DSA:3.40.50.150 1 190 3.2E-69 T 11-10-2018 UP12_13715 e7c0d41a8b34d9caac9949ab77e3b646 191 SUPERFAMILY SSF53335 17 161 1.45E-23 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_13715 e7c0d41a8b34d9caac9949ab77e3b646 191 Pfam PF06962 Putative rRNA methylase 48 186 3.0E-48 T 11-10-2018 IPR010719 Putative rRNA methylase UP12_18440 d32c81c47ad708ca45b33b462ca4e2ba 327 Gene3D G3DSA:3.30.360.10 134 326 2.8E-59 T 11-10-2018 UP12_18440 d32c81c47ad708ca45b33b462ca4e2ba 327 Gene3D G3DSA:3.40.50.720 1 133 2.4E-37 T 11-10-2018 UP12_18440 d32c81c47ad708ca45b33b462ca4e2ba 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 117 8.5E-29 T 11-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 UP12_18440 d32c81c47ad708ca45b33b462ca4e2ba 327 SUPERFAMILY SSF51735 2 151 1.67E-46 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_18440 d32c81c47ad708ca45b33b462ca4e2ba 327 SUPERFAMILY SSF55347 125 289 1.46E-24 T 11-10-2018 UP12_08925 962559bbb6408941520b0155ff76d12c 307 SUPERFAMILY SSF52833 33 241 2.97E-27 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_08925 962559bbb6408941520b0155ff76d12c 307 Gene3D G3DSA:1.10.472.60 74 205 7.8E-46 T 11-10-2018 UP12_08925 962559bbb6408941520b0155ff76d12c 307 Gene3D G3DSA:3.40.30.10 38 230 7.8E-46 T 11-10-2018 UP12_08925 962559bbb6408941520b0155ff76d12c 307 Pfam PF13743 Thioredoxin 37 232 1.3E-31 T 11-10-2018 UP12_04035 17c6dae011e5b63828a184f84b483e7d 133 SUPERFAMILY SSF54427 6 113 6.71E-9 T 11-10-2018 IPR032710 NTF2-like domain superfamily UP12_04035 17c6dae011e5b63828a184f84b483e7d 133 Gene3D G3DSA:3.10.450.50 2 130 1.1E-6 T 11-10-2018 UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 SUPERFAMILY SSF55315 2 78 7.85E-19 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 Pfam PF00588 SpoU rRNA Methylase family 98 238 4.4E-40 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 81 4.7E-22 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 Gene3D G3DSA:3.40.1280.10 77 245 1.0E-57 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 SMART SM00967 7 81 6.5E-20 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 Gene3D G3DSA:3.30.1330.30 1 76 2.2E-14 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 244 2.3E-92 T 11-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 UP12_00630 b675fa2668ec177672c672798ff7e5ef 249 SUPERFAMILY SSF75217 69 245 3.53E-49 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases UP12_13785 a5ff150fcb3d5a2033c52b9d4ad8d4d4 256 Gene3D G3DSA:3.40.50.300 1 227 4.7E-59 T 11-10-2018 UP12_13785 a5ff150fcb3d5a2033c52b9d4ad8d4d4 256 SMART SM00382 32 213 5.3E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_13785 a5ff150fcb3d5a2033c52b9d4ad8d4d4 256 Pfam PF00005 ABC transporter 24 162 7.8E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_13785 a5ff150fcb3d5a2033c52b9d4ad8d4d4 256 SUPERFAMILY SSF52540 4 226 5.08E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13785 a5ff150fcb3d5a2033c52b9d4ad8d4d4 256 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 Gene3D G3DSA:1.10.150.870 761 849 6.3E-9 T 11-10-2018 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 Gene3D G3DSA:3.20.20.140 1 259 7.8E-74 T 11-10-2018 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 Gene3D G3DSA:1.10.10.1600 413 490 1.2E-26 T 11-10-2018 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 SMART SM00481 4 71 1.6E-24 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 Pfam PF14579 Helix-hairpin-helix motif 776 863 1.1E-24 T 11-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 Pfam PF01336 OB-fold nucleic acid binding domain 960 1028 2.4E-10 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 SUPERFAMILY SSF89550 4 243 5.69E-19 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 281 702 8.7E-177 T 11-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 Pfam PF02811 PHP domain 5 166 3.3E-36 T 11-10-2018 IPR004013 PHP domain GO:0003824 UP12_13130 58623a3a7325d7be8bcfa6aa82c3132b 1111 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 989 0.0 T 11-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_15285 8ce5f0677830c2e487a1cc3a935b63c8 292 Pfam PF04231 Endonuclease I 77 285 1.6E-43 T 11-10-2018 IPR007346 Endonuclease I GO:0004518 UP12_15285 8ce5f0677830c2e487a1cc3a935b63c8 292 SUPERFAMILY SSF54060 72 285 1.41E-60 T 11-10-2018 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 SUPERFAMILY SSF51445 6 467 8.16E-169 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 Gene3D G3DSA:3.20.20.80 3 470 2.3E-160 T 11-10-2018 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 424 5.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 298 312 5.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 432 444 5.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 373 5.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 397 5.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 Pfam PF00232 Glycosyl hydrolase family 1 5 467 7.5E-153 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 12 26 - T 11-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UP12_18280 de23dbedda5f9737d48ee14f536e42b8 472 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 365 373 - T 11-10-2018 IPR018120 Glycoside hydrolase family 1, active site UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 3.7E-140 T 11-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 PIRSF PIRSF000149 1 334 2.7E-142 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 1.1E-40 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 SUPERFAMILY SSF51735 3 168 2.82E-68 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 Gene3D G3DSA:3.30.360.10 151 315 5.2E-160 T 11-10-2018 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 SUPERFAMILY SSF55347 152 314 4.76E-74 T 11-10-2018 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 Gene3D G3DSA:3.40.50.720 4 329 5.2E-160 T 11-10-2018 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 11-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.1E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.1E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.1E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.1E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 1.1E-41 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 5.7E-72 T 11-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15930 48cffc4c2252e794e0191dee5acbbf4a 335 SMART SM00846 3 152 4.6E-98 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_07960 1e361371eede1f8fedda24f51fce78db 120 Gene3D G3DSA:3.40.50.2300 2 120 3.6E-40 T 11-10-2018 UP12_07960 1e361371eede1f8fedda24f51fce78db 120 Pfam PF00072 Response regulator receiver domain 5 116 1.6E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_07960 1e361371eede1f8fedda24f51fce78db 120 SMART SM00448 3 115 6.0E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_07960 1e361371eede1f8fedda24f51fce78db 120 SUPERFAMILY SSF52172 4 119 4.27E-40 T 11-10-2018 IPR011006 CheY-like superfamily UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 295 9.0E-113 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 3.9E-82 T 11-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 SUPERFAMILY SSF53850 2 216 1.57E-83 T 11-10-2018 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 2.0E-49 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 2.0E-49 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 2.0E-49 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 2.0E-49 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 2.0E-49 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 SUPERFAMILY SSF54782 220 308 9.94E-23 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 Gene3D G3DSA:3.30.160.40 220 304 4.5E-28 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 295 39.391 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 Gene3D G3DSA:3.40.190.10 101 201 5.9E-87 T 11-10-2018 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 PIRSF PIRSF001438 1 310 2.9E-123 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 Gene3D G3DSA:3.40.190.10 4 209 5.9E-87 T 11-10-2018 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 11-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12350 279ea6e387fea68af16fe46ff2f435a6 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 1.3E-19 T 11-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_16875 461cb2fc068bc247b408c071b8b19373 365 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 3 358 1.3E-64 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_16875 461cb2fc068bc247b408c071b8b19373 365 Pfam PF03845 Spore germination protein 4 316 1.2E-63 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_16875 461cb2fc068bc247b408c071b8b19373 365 Gene3D G3DSA:1.20.1740.10 1 364 7.8E-11 T 11-10-2018 UP12_02940 f718c4b4ef622f1e622fef3087721742 201 Gene3D G3DSA:1.10.10.60 13 61 6.6E-20 T 11-10-2018 UP12_02940 f718c4b4ef622f1e622fef3087721742 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.3E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02940 f718c4b4ef622f1e622fef3087721742 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.3E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02940 f718c4b4ef622f1e622fef3087721742 201 SUPERFAMILY SSF46689 9 84 1.49E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_02940 f718c4b4ef622f1e622fef3087721742 201 SUPERFAMILY SSF48498 85 198 8.9E-40 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_02940 f718c4b4ef622f1e622fef3087721742 201 Pfam PF08360 QacR-like protein, C-terminal region 74 197 6.9E-18 T 11-10-2018 IPR013571 Transcription regulator QacR, C-terminal GO:0003700|GO:0045892 UP12_02940 f718c4b4ef622f1e622fef3087721742 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_02940 f718c4b4ef622f1e622fef3087721742 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 2.5E-16 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02940 f718c4b4ef622f1e622fef3087721742 201 Gene3D G3DSA:1.10.357.10 62 201 8.0E-33 T 11-10-2018 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 SMART SM00493 3 126 1.6E-18 T 11-10-2018 IPR006171 TOPRIM domain UP12_02355 65e526c80a91f727c509858b2000c2d8 728 SUPERFAMILY SSF56712 3 597 1.18E-172 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain UP12_02355 65e526c80a91f727c509858b2000c2d8 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 186 204 1.0E-27 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 305 314 1.0E-27 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 387 403 1.0E-27 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 510 524 1.0E-27 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 1.0E-27 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 Hamap MF_00953 DNA topoisomerase 3 [topB]. 3 636 67.733 T 11-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 Pfam PF01751 Toprim domain 5 134 7.5E-13 T 11-10-2018 IPR006171 TOPRIM domain UP12_02355 65e526c80a91f727c509858b2000c2d8 728 Gene3D G3DSA:2.70.20.10 210 475 2.2E-146 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 299 314 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 SMART SM00436 126 216 3.4E-40 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 Gene3D G3DSA:1.10.460.10 160 591 2.2E-146 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 727 3.9E-293 T 11-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 Gene3D G3DSA:1.10.290.10 271 401 2.2E-146 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 SMART SM00437 262 547 5.1E-98 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 Gene3D G3DSA:3.40.50.140 4 154 6.3E-51 T 11-10-2018 UP12_02355 65e526c80a91f727c509858b2000c2d8 728 Pfam PF01131 DNA topoisomerase 152 581 4.5E-120 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 SUPERFAMILY SSF54631 205 342 2.27E-29 T 11-10-2018 UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 Gene3D G3DSA:3.10.580.10 197 348 1.3E-48 T 11-10-2018 UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 Pfam PF01595 Domain of unknown function DUF21 12 202 6.3E-47 T 11-10-2018 IPR002550 CNNM, transmembrane domain UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 SMART SM01091 355 432 5.2E-18 T 11-10-2018 IPR005170 Transporter-associated domain UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 SUPERFAMILY SSF56176 353 430 4.36E-16 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 Gene3D G3DSA:3.30.465.10 349 438 7.5E-16 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 Pfam PF03471 Transporter associated domain 356 430 7.2E-16 T 11-10-2018 IPR005170 Transporter-associated domain UP12_04895 423533e04efb402c8de0f2f7c9d9d401 460 Pfam PF00571 CBS domain 223 271 3.5E-6 T 11-10-2018 IPR000644 CBS domain UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 Gene3D G3DSA:1.50.10.10 1 457 8.0E-193 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 SMART SM01067 463 548 3.4E-29 T 11-10-2018 IPR001956 Carbohydrate-binding module 3 GO:0005975|GO:0030248 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 Gene3D G3DSA:2.60.40.710 458 616 1.9E-55 T 11-10-2018 IPR036966 Carbohydrate-binding module 3 superfamily GO:0005975|GO:0030248 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 412 430 - T 11-10-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 SUPERFAMILY SSF48208 3 451 2.01E-164 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 ProSitePatterns PS00592 Glycosyl hydrolases family 9 active sites signature 1. 362 378 - T 11-10-2018 IPR018221 Glycoside hydrolase family 9, His active site KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 SUPERFAMILY SSF49384 461 614 1.73E-50 T 11-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 Pfam PF00942 Cellulose binding domain 465 547 2.7E-12 T 11-10-2018 IPR001956 Carbohydrate-binding module 3 GO:0005975|GO:0030248 UP12_08090 6eaf8fd89bb9d638d1ae3d71c62bc71a 616 Pfam PF00759 Glycosyl hydrolase family 9 6 434 3.1E-146 T 11-10-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 UP12_12735 66839d18322442d63ff48c550abce71c 289 Pfam PF01555 DNA methylase 3 276 1.9E-54 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 UP12_12735 66839d18322442d63ff48c550abce71c 289 SUPERFAMILY SSF53335 11 281 4.66E-50 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_12735 66839d18322442d63ff48c550abce71c 289 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 236 254 1.4E-32 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_12735 66839d18322442d63ff48c550abce71c 289 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 217 234 1.4E-32 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_12735 66839d18322442d63ff48c550abce71c 289 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 21 41 1.4E-32 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_12735 66839d18322442d63ff48c550abce71c 289 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 259 279 1.4E-32 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_18565 b7f35b010057efb5d3cd2319fdea22c7 112 Pfam PF08274 PhnA Zinc-Ribbon 4 32 2.8E-14 T 11-10-2018 IPR013987 PhnA protein, N-terminal UP12_18565 b7f35b010057efb5d3cd2319fdea22c7 112 Pfam PF03831 PhnA domain 45 112 1.9E-33 T 11-10-2018 IPR013988 PhnA protein, C-terminal UP12_18565 b7f35b010057efb5d3cd2319fdea22c7 112 Gene3D G3DSA:2.20.25.10 1 42 1.0E-19 T 11-10-2018 UP12_18565 b7f35b010057efb5d3cd2319fdea22c7 112 Gene3D G3DSA:2.30.30.40 43 112 1.2E-34 T 11-10-2018 UP12_18565 b7f35b010057efb5d3cd2319fdea22c7 112 SUPERFAMILY SSF57783 3 36 4.25E-14 T 11-10-2018 UP12_18565 b7f35b010057efb5d3cd2319fdea22c7 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 3 111 5.9E-51 T 11-10-2018 IPR004624 PhnA protein UP12_18565 b7f35b010057efb5d3cd2319fdea22c7 112 SUPERFAMILY SSF82057 40 112 1.74E-28 T 11-10-2018 UP12_15165 e9c98e86528017f5edd70910178f6b1f 109 SUPERFAMILY SSF52833 2 105 1.23E-46 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_15165 e9c98e86528017f5edd70910178f6b1f 109 Pfam PF07315 Protein of unknown function (DUF1462) 9 100 1.1E-43 T 11-10-2018 IPR009190 Protein of unknown function DUF1462 UP12_15165 e9c98e86528017f5edd70910178f6b1f 109 Gene3D G3DSA:3.40.30.30 1 105 3.9E-43 T 11-10-2018 IPR038218 YuzD-like superfamily UP12_15165 e9c98e86528017f5edd70910178f6b1f 109 PIRSF PIRSF010603 1 106 8.6E-50 T 11-10-2018 IPR009190 Protein of unknown function DUF1462 UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 33 46 - T 11-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 Gene3D G3DSA:2.60.120.560 358 480 4.7E-18 T 11-10-2018 UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 SMART SM00640 33 445 2.9E-153 T 11-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 33 339 1.3E-107 T 11-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 Gene3D G3DSA:2.115.10.20 1 357 1.0E-118 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 18 455 2.1E-172 T 11-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 SUPERFAMILY SSF49899 340 480 4.11E-21 T 11-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 SUPERFAMILY SSF75005 24 340 3.45E-115 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UP12_17750 8545ce38aa4c77abe36a4856f10a1ca0 485 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 343 475 1.0E-14 T 11-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal UP12_16380 716e0501f84591194506138fc155d003 661 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 658 0.0 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 UP12_16380 716e0501f84591194506138fc155d003 661 Pfam PF02151 UvrB/uvrC motif 625 659 4.0E-8 T 11-10-2018 IPR001943 UVR domain GO:0005515 UP12_16380 716e0501f84591194506138fc155d003 661 Gene3D G3DSA:3.40.50.300 1 242 2.9E-84 T 11-10-2018 UP12_16380 716e0501f84591194506138fc155d003 661 Pfam PF12344 Ultra-violet resistance protein B 551 593 1.2E-20 T 11-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain UP12_16380 716e0501f84591194506138fc155d003 661 Gene3D G3DSA:3.40.50.300 248 413 2.6E-54 T 11-10-2018 UP12_16380 716e0501f84591194506138fc155d003 661 SUPERFAMILY SSF52540 324 574 5.69E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16380 716e0501f84591194506138fc155d003 661 SUPERFAMILY SSF46600 615 659 7.98E-10 T 11-10-2018 IPR036876 UVR domain superfamily UP12_16380 716e0501f84591194506138fc155d003 661 Pfam PF04851 Type III restriction enzyme, res subunit 13 130 6.8E-12 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UP12_16380 716e0501f84591194506138fc155d003 661 Pfam PF00271 Helicase conserved C-terminal domain 440 544 2.7E-19 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_16380 716e0501f84591194506138fc155d003 661 SMART SM00487 9 424 2.5E-24 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_16380 716e0501f84591194506138fc155d003 661 Gene3D G3DSA:3.40.50.300 414 595 1.4E-53 T 11-10-2018 UP12_16380 716e0501f84591194506138fc155d003 661 Gene3D G3DSA:4.10.860.10 600 660 1.3E-5 T 11-10-2018 UP12_16380 716e0501f84591194506138fc155d003 661 SMART SM00490 459 545 2.7E-20 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_16380 716e0501f84591194506138fc155d003 661 SUPERFAMILY SSF52540 3 414 4.51E-144 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16380 716e0501f84591194506138fc155d003 661 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 660 45.062 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 UP12_05415 4e8147770617b6bcc960fc1505d81d3f 279 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 156 182 - T 11-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 UP12_05415 4e8147770617b6bcc960fc1505d81d3f 279 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 125 140 - T 11-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 UP12_05415 4e8147770617b6bcc960fc1505d81d3f 279 Gene3D G3DSA:1.10.600.10 1 278 5.0E-102 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_05415 4e8147770617b6bcc960fc1505d81d3f 279 Pfam PF00494 Squalene/phytoene synthase 16 268 1.3E-76 T 11-10-2018 UP12_05415 4e8147770617b6bcc960fc1505d81d3f 279 SUPERFAMILY SSF48576 7 275 3.74E-80 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_12190 4a809691bc59621ab03f717748089bf5 425 SMART SM00257 3 48 7.3E-18 T 11-10-2018 IPR018392 LysM domain UP12_12190 4a809691bc59621ab03f717748089bf5 425 Pfam PF01476 LysM domain 4 48 4.6E-16 T 11-10-2018 IPR018392 LysM domain UP12_12190 4a809691bc59621ab03f717748089bf5 425 SUPERFAMILY SSF54106 2 48 1.28E-11 T 11-10-2018 UP12_12190 4a809691bc59621ab03f717748089bf5 425 Gene3D G3DSA:3.10.350.10 1 60 3.6E-16 T 11-10-2018 IPR036779 LysM domain superfamily UP12_12190 4a809691bc59621ab03f717748089bf5 425 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 6.2E-27 T 11-10-2018 IPR014248 Spore coat assembly protein SafA UP12_01950 f1f75a85f02c56013f7e2bd983e88a6a 128 Pfam PF11033 Competence protein J (ComJ) 9 126 4.8E-48 T 11-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ UP12_01950 f1f75a85f02c56013f7e2bd983e88a6a 128 ProDom PD081734 COMPETENCE J NIN DNA-ENTRY MEMBRANE INHIBITOR NUCLEASE 10 112 1.0E-24 T 11-10-2018 IPR020354 Competence, DNA-entry nuclease inhibitor, ComJ UP12_01950 f1f75a85f02c56013f7e2bd983e88a6a 128 Gene3D G3DSA:2.60.34.30 2 128 1.0E-39 T 11-10-2018 IPR038691 DNA-entry nuclease inhibitor, ComJ superfamily UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Gene3D G3DSA:3.30.1490.360 26 93 8.2E-24 T 11-10-2018 UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 315 448 2.0E-58 T 11-10-2018 IPR020287 Tail sheath protein, C-terminal domain UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Gene3D G3DSA:3.30.160.610 94 184 2.3E-25 T 11-10-2018 UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 100 181 6.7E-14 T 11-10-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Gene3D G3DSA:3.30.360.90 377 448 1.1E-19 T 11-10-2018 UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Gene3D G3DSA:1.10.10.2290 251 331 1.4E-63 T 11-10-2018 UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Pfam PF17482 Phage tail sheath C-terminal domain 340 448 2.4E-26 T 11-10-2018 IPR020287 Tail sheath protein, C-terminal domain UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Gene3D G3DSA:3.40.50.11790 190 361 1.4E-63 T 11-10-2018 UP12_14220 76c7f27feba256df4e2f631542fe7baf 448 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 185 333 1.0E-38 T 11-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain UP12_11130 2f153f40bd83647b20f08d9784b39494 113 SUPERFAMILY SSF47413 2 69 4.83E-18 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_11130 2f153f40bd83647b20f08d9784b39494 113 SMART SM00530 7 63 1.2E-15 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_11130 2f153f40bd83647b20f08d9784b39494 113 Pfam PF08671 Anti-repressor SinI 76 103 1.5E-12 T 11-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 UP12_11130 2f153f40bd83647b20f08d9784b39494 113 SUPERFAMILY SSF47406 76 109 1.26E-11 T 11-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 UP12_11130 2f153f40bd83647b20f08d9784b39494 113 Gene3D G3DSA:1.10.260.40 3 113 2.1E-32 T 11-10-2018 UP12_11130 2f153f40bd83647b20f08d9784b39494 113 Pfam PF01381 Helix-turn-helix 8 60 7.7E-17 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 Pfam PF07478 D-ala D-ala ligase C-terminus 142 343 5.2E-80 T 11-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 101 112 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 289 317 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 Pfam PF01820 D-ala D-ala ligase N-terminus 5 123 1.2E-30 T 11-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 Gene3D G3DSA:3.30.470.20 123 349 4.9E-82 T 11-10-2018 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 346 5.5E-118 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 PIRSF PIRSF039102 1 355 8.0E-116 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 SUPERFAMILY SSF56059 134 351 7.63E-61 T 11-10-2018 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 Gene3D G3DSA:3.30.1490.20 149 221 4.9E-82 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 347 41.562 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 SUPERFAMILY SSF52440 2 133 2.49E-36 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_02485 8c8c056f426ee28ed706bb07b8bd7229 360 Gene3D G3DSA:3.40.50.20 1 122 6.4E-37 T 11-10-2018 UP12_06220 fb1f5008a814f019f663b0a2a6181be3 326 SUPERFAMILY SSF52518 3 191 1.57E-71 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_06220 fb1f5008a814f019f663b0a2a6181be3 326 Gene3D G3DSA:3.40.50.920 192 325 2.7E-49 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_06220 fb1f5008a814f019f663b0a2a6181be3 326 SMART SM00861 4 179 4.2E-67 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_06220 fb1f5008a814f019f663b0a2a6181be3 326 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 4.9E-52 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_06220 fb1f5008a814f019f663b0a2a6181be3 326 Pfam PF02780 Transketolase, C-terminal domain 193 316 1.1E-42 T 11-10-2018 IPR033248 Transketolase, C-terminal domain UP12_06220 fb1f5008a814f019f663b0a2a6181be3 326 SUPERFAMILY SSF52922 190 323 1.57E-43 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_06220 fb1f5008a814f019f663b0a2a6181be3 326 Gene3D G3DSA:3.40.50.970 1 191 2.0E-89 T 11-10-2018 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 PIRSF PIRSF004640 1 361 1.6E-156 T 11-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 8.4E-132 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 SUPERFAMILY SSF51717 15 236 2.28E-19 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 Gene3D G3DSA:3.30.413.10 261 360 6.3E-36 T 11-10-2018 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 34.544 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 Gene3D G3DSA:3.20.20.20 1 259 2.1E-110 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 Pfam PF04551 GcpE protein 10 351 1.2E-140 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 UP12_11350 8e99b02630cf546c71d95e7dba7edfb9 370 SUPERFAMILY SSF56014 264 356 5.07E-14 T 11-10-2018 UP12_05080 35efe2dd250be734c187d5be64e70af5 114 SUPERFAMILY SSF109915 1 112 8.5E-44 T 11-10-2018 IPR035945 YhaI-like superfamily UP12_05080 35efe2dd250be734c187d5be64e70af5 114 Pfam PF08963 Protein of unknown function (DUF1878) 2 109 3.3E-45 T 11-10-2018 IPR015058 Protein of unknown function DUF1878 UP12_05080 35efe2dd250be734c187d5be64e70af5 114 ProDom PD073069 YHAI 3D-STRUCTURE 9 112 5.0E-33 T 11-10-2018 IPR015058 Protein of unknown function DUF1878 UP12_05080 35efe2dd250be734c187d5be64e70af5 114 Gene3D G3DSA:1.10.3750.10 1 114 4.1E-36 T 11-10-2018 IPR035945 YhaI-like superfamily UP12_14325 32af969454347358350c07d37fae8c8f 127 Gene3D G3DSA:1.20.140.160 2 125 5.1E-5 T 11-10-2018 UP12_14325 32af969454347358350c07d37fae8c8f 127 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 9 126 9.2E-21 T 11-10-2018 IPR006524 Transcription activator, ArpU family UP12_10770 04f3e4ced079bfaa12f234bba6745d9c 448 Pfam PF02378 Phosphotransferase system, EIIC 26 350 5.4E-70 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_10770 04f3e4ced079bfaa12f234bba6745d9c 448 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 424 1.4E-164 T 11-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 UP12_10770 04f3e4ced079bfaa12f234bba6745d9c 448 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 9 424 1.4E-164 T 11-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 UP12_10770 04f3e4ced079bfaa12f234bba6745d9c 448 PIRSF PIRSF006351 1 433 4.1E-145 T 11-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 UP12_11315 f70151db9b59086d33393fcfb92caab0 711 Pfam PF00905 Penicillin binding protein transpeptidase domain 351 675 5.3E-68 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_11315 f70151db9b59086d33393fcfb92caab0 711 Gene3D G3DSA:1.10.10.1230 92 193 1.9E-234 T 11-10-2018 UP12_11315 f70151db9b59086d33393fcfb92caab0 711 SUPERFAMILY SSF56519 63 318 5.36E-36 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UP12_11315 f70151db9b59086d33393fcfb92caab0 711 Gene3D G3DSA:3.40.710.10 318 666 1.9E-234 T 11-10-2018 UP12_11315 f70151db9b59086d33393fcfb92caab0 711 Gene3D G3DSA:3.90.1310.30 67 571 1.9E-234 T 11-10-2018 UP12_11315 f70151db9b59086d33393fcfb92caab0 711 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 302 7.5E-40 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UP12_11315 f70151db9b59086d33393fcfb92caab0 711 SUPERFAMILY SSF56601 270 683 3.89E-62 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_15080 319741072554a3a11ec7573c5fea2b65 378 SMART SM01003 4 136 1.7E-77 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UP12_15080 319741072554a3a11ec7573c5fea2b65 378 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 2.3E-84 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UP12_15080 319741072554a3a11ec7573c5fea2b65 378 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 9.6E-48 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal UP12_15080 319741072554a3a11ec7573c5fea2b65 378 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 11-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 UP12_15080 319741072554a3a11ec7573c5fea2b65 378 Gene3D G3DSA:3.40.50.720 3 353 6.2E-141 T 11-10-2018 UP12_15080 319741072554a3a11ec7573c5fea2b65 378 SMART SM01002 148 297 6.5E-89 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UP12_15080 319741072554a3a11ec7573c5fea2b65 378 Gene3D G3DSA:3.40.50.720 129 305 6.2E-141 T 11-10-2018 UP12_15080 319741072554a3a11ec7573c5fea2b65 378 PIRSF PIRSF000183 1 371 2.1E-189 T 11-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 UP12_15080 319741072554a3a11ec7573c5fea2b65 378 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 8.4E-191 T 11-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 UP12_15080 319741072554a3a11ec7573c5fea2b65 378 SUPERFAMILY SSF52283 1 360 1.62E-65 T 11-10-2018 UP12_15080 319741072554a3a11ec7573c5fea2b65 378 SUPERFAMILY SSF51735 136 303 1.27E-48 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_18210 5698acc1a4c05c78e26927169a5024e8 115 SUPERFAMILY SSF47413 3 67 2.95E-15 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_18210 5698acc1a4c05c78e26927169a5024e8 115 Gene3D G3DSA:1.10.260.40 1 114 1.1E-20 T 11-10-2018 UP12_18210 5698acc1a4c05c78e26927169a5024e8 115 Pfam PF01381 Helix-turn-helix 9 60 1.7E-13 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_18210 5698acc1a4c05c78e26927169a5024e8 115 SMART SM00530 5 60 7.6E-15 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 Gene3D G3DSA:1.10.8.630 1 114 2.1E-25 T 11-10-2018 UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 Gene3D G3DSA:3.40.50.300 252 445 1.2E-77 T 11-10-2018 UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 SUPERFAMILY SSF52540 530 703 1.04E-32 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 SUPERFAMILY SSF52540 262 445 4.28E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 Pfam PF00271 Helicase conserved C-terminal domain 558 659 5.3E-8 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 Pfam PF04851 Type III restriction enzyme, res subunit 264 428 3.3E-19 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 SMART SM00487 261 452 1.4E-25 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 TIGRFAM TIGR00595 priA: primosomal protein N' 289 799 1.4E-227 T 11-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 SMART SM00490 563 660 9.0E-9 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_07650 74af9e70fc01d9e162a12d6b11b5138a 802 Hamap MF_00983 Probable primosomal protein N' [priA]. 8 801 25.673 T 11-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Gene3D G3DSA:2.10.230.10 147 211 4.1E-36 T 11-10-2018 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Pfam PF00684 DnaJ central domain 147 211 7.7E-13 T 11-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Gene3D G3DSA:2.60.260.20 117 253 4.1E-36 T 11-10-2018 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 SUPERFAMILY SSF46565 1 103 1.44E-37 T 11-10-2018 IPR036869 Chaperone J-domain superfamily UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Pfam PF00226 DnaJ domain 5 66 1.0E-26 T 11-10-2018 IPR001623 DnaJ domain UP12_11555 87bf55c560096739a6b08b345ed56b34 377 SUPERFAMILY SSF57938 134 215 3.53E-18 T 11-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily UP12_11555 87bf55c560096739a6b08b345ed56b34 377 SUPERFAMILY SSF49493 114 260 1.44E-20 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Gene3D G3DSA:1.10.287.110 1 112 2.9E-38 T 11-10-2018 IPR036869 Chaperone J-domain superfamily UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Pfam PF01556 DnaJ C terminal domain 120 337 7.4E-45 T 11-10-2018 IPR002939 Chaperone DnaJ, C-terminal UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 373 41.36 T 11-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 353 8.3E-141 T 11-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 SMART SM00271 4 61 2.7E-30 T 11-10-2018 IPR001623 DnaJ domain UP12_11555 87bf55c560096739a6b08b345ed56b34 377 Gene3D G3DSA:2.60.260.20 257 337 6.9E-31 T 11-10-2018 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 SUPERFAMILY SSF49493 262 348 2.22E-25 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 UP12_11555 87bf55c560096739a6b08b345ed56b34 377 PRINTS PR00625 DnaJ domain signature 25 40 5.3E-31 T 11-10-2018 IPR001623 DnaJ domain UP12_11555 87bf55c560096739a6b08b345ed56b34 377 PRINTS PR00625 DnaJ domain signature 41 61 5.3E-31 T 11-10-2018 IPR001623 DnaJ domain UP12_11555 87bf55c560096739a6b08b345ed56b34 377 PRINTS PR00625 DnaJ domain signature 61 80 5.3E-31 T 11-10-2018 IPR001623 DnaJ domain UP12_11555 87bf55c560096739a6b08b345ed56b34 377 PRINTS PR00625 DnaJ domain signature 7 25 5.3E-31 T 11-10-2018 IPR001623 DnaJ domain UP12_11555 87bf55c560096739a6b08b345ed56b34 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 11-10-2018 IPR018253 DnaJ domain, conserved site UP12_11420 49f85c8a51f1d88584342ab50ad2fc31 238 Gene3D G3DSA:3.40.50.150 1 164 5.8E-55 T 11-10-2018 UP12_11420 49f85c8a51f1d88584342ab50ad2fc31 238 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 232 3.8E-72 T 11-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 UP12_11420 49f85c8a51f1d88584342ab50ad2fc31 238 PIRSF PIRSF018637 4 238 1.3E-87 T 11-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 UP12_11420 49f85c8a51f1d88584342ab50ad2fc31 238 SUPERFAMILY SSF53335 12 100 5.32E-6 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_16065 ce53348074ef92dd2b2ab9ce191cf01a 156 Gene3D G3DSA:1.10.260.40 1 112 1.9E-21 T 11-10-2018 UP12_16065 ce53348074ef92dd2b2ab9ce191cf01a 156 Pfam PF08671 Anti-repressor SinI 125 148 2.7E-8 T 11-10-2018 IPR010981 SinR repressor/SinI anti-repressor, dimerisation domain GO:0006355|GO:0046983 UP12_16065 ce53348074ef92dd2b2ab9ce191cf01a 156 SUPERFAMILY SSF47413 2 65 3.49E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_16065 ce53348074ef92dd2b2ab9ce191cf01a 156 SMART SM00530 5 61 1.6E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_16065 ce53348074ef92dd2b2ab9ce191cf01a 156 SUPERFAMILY SSF47406 125 149 8.24E-5 T 11-10-2018 IPR036281 SinR repressor/SinI anti-repressor, dimerisation domain superfamily GO:0006355|GO:0046983 UP12_16065 ce53348074ef92dd2b2ab9ce191cf01a 156 Pfam PF01381 Helix-turn-helix 6 61 2.3E-15 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_02165 92786b20f149ad7839949b0a1f7a1f30 474 SMART SM00345 19 78 3.4E-14 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02165 92786b20f149ad7839949b0a1f7a1f30 474 SUPERFAMILY SSF53383 92 469 4.38E-67 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_02165 92786b20f149ad7839949b0a1f7a1f30 474 Gene3D G3DSA:1.10.10.10 1 89 3.9E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02165 92786b20f149ad7839949b0a1f7a1f30 474 Gene3D G3DSA:3.40.640.10 94 466 1.2E-120 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_02165 92786b20f149ad7839949b0a1f7a1f30 474 SUPERFAMILY SSF46785 12 87 6.63E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02165 92786b20f149ad7839949b0a1f7a1f30 474 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 78 6.0E-15 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02165 92786b20f149ad7839949b0a1f7a1f30 474 Pfam PF00155 Aminotransferase class I and II 118 418 1.1E-20 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 11-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 SUPERFAMILY SSF46906 70 143 1.57E-27 T 11-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 2.9E-26 T 11-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 SMART SM00649 12 143 1.2E-87 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 8.0E-16 T 11-10-2018 UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.847 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 Gene3D G3DSA:3.30.1550.10 5 74 3.4E-34 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 1.7E-30 T 11-10-2018 IPR020784 Ribosomal protein L11, N-terminal UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 SUPERFAMILY SSF54747 4 87 1.83E-30 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 Gene3D G3DSA:1.10.10.250 75 143 6.1E-30 T 11-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily UP12_00655 9ed3a23a8aeea2f448ff0ccbee343cb1 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 144 3.2E-64 T 11-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 SUPERFAMILY SSF54106 28 71 2.22E-11 T 11-10-2018 UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 Pfam PF01476 LysM domain 29 70 1.5E-14 T 11-10-2018 IPR018392 LysM domain UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 Pfam PF01476 LysM domain 80 121 2.4E-14 T 11-10-2018 IPR018392 LysM domain UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 Pfam PF06725 3D domain 202 263 2.0E-22 T 11-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 SUPERFAMILY SSF54106 79 121 1.2E-12 T 11-10-2018 UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 SMART SM00257 79 122 2.8E-16 T 11-10-2018 IPR018392 LysM domain UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 SMART SM00257 28 71 7.6E-17 T 11-10-2018 IPR018392 LysM domain UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 Gene3D G3DSA:3.10.350.10 25 77 2.9E-18 T 11-10-2018 IPR036779 LysM domain superfamily UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 Gene3D G3DSA:3.10.350.10 78 127 1.8E-19 T 11-10-2018 IPR036779 LysM domain superfamily UP12_09475 ad2827a25c2a25aded1fdbbb3cf94475 263 SUPERFAMILY SSF50685 203 250 1.01E-7 T 11-10-2018 IPR036908 RlpA-like domain superfamily UP12_01560 632272441fc78c15e52ea28efb2a0838 313 Gene3D G3DSA:3.40.50.2300 1 129 5.1E-22 T 11-10-2018 UP12_01560 632272441fc78c15e52ea28efb2a0838 313 SMART SM00448 1 114 2.3E-19 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_01560 632272441fc78c15e52ea28efb2a0838 313 Pfam PF00072 Response regulator receiver domain 4 114 1.2E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_01560 632272441fc78c15e52ea28efb2a0838 313 SUPERFAMILY SSF52172 2 174 1.85E-23 T 11-10-2018 IPR011006 CheY-like superfamily UP12_01560 632272441fc78c15e52ea28efb2a0838 313 Pfam PF08664 YcbB domain 162 300 4.0E-49 T 11-10-2018 IPR013972 YcbB domain UP12_16150 7253bb459d7fef23bf14d963af62963a 198 SUPERFAMILY SSF52096 10 194 2.16E-73 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_16150 7253bb459d7fef23bf14d963af62963a 198 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 11-10-2018 IPR018215 ClpP, Ser active site UP12_16150 7253bb459d7fef23bf14d963af62963a 198 Gene3D G3DSA:3.90.226.10 1 196 5.1E-84 T 11-10-2018 UP12_16150 7253bb459d7fef23bf14d963af62963a 198 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 2.2E-53 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UP12_16150 7253bb459d7fef23bf14d963af62963a 198 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 2.2E-53 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UP12_16150 7253bb459d7fef23bf14d963af62963a 198 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 2.2E-53 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UP12_16150 7253bb459d7fef23bf14d963af62963a 198 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 2.2E-53 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UP12_16150 7253bb459d7fef23bf14d963af62963a 198 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 2.2E-53 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UP12_16150 7253bb459d7fef23bf14d963af62963a 198 Pfam PF00574 Clp protease 13 192 2.3E-87 T 11-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UP12_16150 7253bb459d7fef23bf14d963af62963a 198 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 11-10-2018 IPR033135 ClpP, histidine active site UP12_16150 7253bb459d7fef23bf14d963af62963a 198 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 5.7E-109 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UP12_16150 7253bb459d7fef23bf14d963af62963a 198 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.359 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 UP12_05235 b598cd1ddd614b981969afa710f4a066 76 Pfam PF08858 IDEAL domain 34 70 3.9E-13 T 11-10-2018 IPR014957 IDEAL domain UP12_05235 b598cd1ddd614b981969afa710f4a066 76 SMART SM00914 34 70 2.4E-12 T 11-10-2018 IPR014957 IDEAL domain UP12_05235 b598cd1ddd614b981969afa710f4a066 76 Gene3D G3DSA:4.10.810.10 26 76 7.9E-9 T 11-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 UP12_13585 4566ebae3933216fe472bcb98db2c056 103 Gene3D G3DSA:3.40.250.10 3 102 3.7E-28 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_13585 4566ebae3933216fe472bcb98db2c056 103 SUPERFAMILY SSF52821 2 101 1.13E-27 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_13585 4566ebae3933216fe472bcb98db2c056 103 Pfam PF00581 Rhodanese-like domain 8 96 1.3E-13 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_13585 4566ebae3933216fe472bcb98db2c056 103 SMART SM00450 7 101 2.4E-18 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_09050 06c752c78bbb16a18a94aab89e7e8df4 139 SMART SM00347 14 114 3.2E-20 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09050 06c752c78bbb16a18a94aab89e7e8df4 139 Gene3D G3DSA:1.10.10.10 1 131 2.9E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09050 06c752c78bbb16a18a94aab89e7e8df4 139 SUPERFAMILY SSF46785 2 131 4.56E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09050 06c752c78bbb16a18a94aab89e7e8df4 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 38 54 6.6E-5 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09050 06c752c78bbb16a18a94aab89e7e8df4 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 70 6.6E-5 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09050 06c752c78bbb16a18a94aab89e7e8df4 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 124 6.6E-5 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_09050 06c752c78bbb16a18a94aab89e7e8df4 139 Pfam PF01047 MarR family 31 79 9.8E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_02395 da24d649f75a3ab5d2261d35ffad78b5 517 Pfam PF14449 Pre-toxin TG 243 308 1.6E-19 T 11-10-2018 IPR027797 Pre-toxin TG domain UP12_02395 da24d649f75a3ab5d2261d35ffad78b5 517 Pfam PF04740 LXG domain of WXG superfamily 1 188 6.2E-40 T 11-10-2018 IPR006829 LXG domain UP12_13255 79e7ff7d1f2b042d209da445551018a7 306 Pfam PF01497 Periplasmic binding protein 62 281 1.4E-29 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_13255 79e7ff7d1f2b042d209da445551018a7 306 Gene3D G3DSA:3.40.50.1980 49 137 1.5E-25 T 11-10-2018 UP12_13255 79e7ff7d1f2b042d209da445551018a7 306 Gene3D G3DSA:3.40.50.1980 138 306 7.7E-58 T 11-10-2018 UP12_13255 79e7ff7d1f2b042d209da445551018a7 306 SUPERFAMILY SSF53807 39 299 5.1E-52 T 11-10-2018 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 154 234 1.3E-11 T 11-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 48 106 2.5E-6 T 11-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 SUPERFAMILY SSF81464 14 114 5.07E-17 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 Gene3D G3DSA:2.60.40.2600 127 355 2.5E-62 T 11-10-2018 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 SUPERFAMILY SSF46626 259 353 4.59E-17 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 174 228 - T 11-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 33 244 3.7E-48 T 11-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 SUPERFAMILY SSF49503 127 280 1.34E-37 T 11-10-2018 IPR008972 Cupredoxin UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 Pfam PF00034 Cytochrome c 261 353 2.0E-12 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 PRINTS PR01166 Cytochrome c oxidase subunit II signature 96 116 6.4E-5 T 11-10-2018 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 PRINTS PR01166 Cytochrome c oxidase subunit II signature 84 96 6.4E-5 T 11-10-2018 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 PRINTS PR01166 Cytochrome c oxidase subunit II signature 217 234 6.4E-5 T 11-10-2018 UP12_07210 7a0260977d696e748dec9e8a43851d2f 355 Gene3D G3DSA:1.10.287.90 25 115 1.0E-20 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 66 501 5.4E-216 T 11-10-2018 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 Gene3D G3DSA:3.80.30.20 209 442 1.8E-91 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 SUPERFAMILY SSF102114 198 433 1.83E-63 T 11-10-2018 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 SMART SM00729 210 428 9.7E-64 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 Pfam PF01938 TRAM domain 440 501 1.9E-16 T 11-10-2018 IPR002792 TRAM domain UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 66 498 3.2E-166 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 Pfam PF04055 Radical SAM superfamily 214 385 3.9E-35 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 Pfam PF00919 Uncharacterized protein family UPF0004 66 167 9.5E-30 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 65 502 75.02 T 11-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 Gene3D G3DSA:3.40.50.12160 65 199 3.5E-35 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily UP12_08340 6375620c827af41b0915cc94e0c5eba3 508 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 214 234 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 Gene3D G3DSA:1.10.150.530 16 75 3.4E-23 T 11-10-2018 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 Pfam PF13394 4Fe-4S single cluster domain 122 228 1.9E-6 T 11-10-2018 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 Pfam PF04055 Radical SAM superfamily 117 287 6.6E-17 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 14 356 74.004 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 SUPERFAMILY SSF102114 109 329 6.8E-14 T 11-10-2018 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 PIRSF PIRSF006004 7 360 4.1E-141 T 11-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 Gene3D G3DSA:3.20.20.70 77 341 1.5E-99 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_07670 177e21880647904d2010d782aa8d1f2b 360 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 11 360 2.2E-169 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 UP12_15525 8b2dca7a68ec8583a2c15febeb9173f7 364 Pfam PF03845 Spore germination protein 8 325 4.3E-82 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_15525 8b2dca7a68ec8583a2c15febeb9173f7 364 PIRSF PIRSF006060 1 294 1.0E-10 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_15525 8b2dca7a68ec8583a2c15febeb9173f7 364 PIRSF PIRSF006060 296 363 1.7 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_15525 8b2dca7a68ec8583a2c15febeb9173f7 364 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 7 361 1.7E-83 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 126 3.3E-17 T 11-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 Gene3D G3DSA:3.20.20.120 119 347 4.1E-137 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 SMART SM00922 143 235 9.5E-21 T 11-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 Gene3D G3DSA:3.30.390.10 9 360 4.1E-137 T 11-10-2018 IPR029017 Enolase-like, N-terminal UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 333 3.2E-142 T 11-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 2 360 45.745 T 11-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 Pfam PF13378 Enolase C-terminal domain-like 146 355 2.3E-44 T 11-10-2018 IPR029065 Enolase C-terminal domain-like UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 SUPERFAMILY SSF54826 2 127 2.41E-34 T 11-10-2018 UP12_13890 d8fd39d4cb3c10498754adc3402a18f8 374 SUPERFAMILY SSF51604 125 360 6.68E-67 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UP12_03435 310fb1a83a645fc48a6518652eeaf22f 580 Gene3D G3DSA:3.20.20.140 82 325 8.3E-80 T 11-10-2018 UP12_03435 310fb1a83a645fc48a6518652eeaf22f 580 Gene3D G3DSA:2.30.40.10 26 360 8.3E-80 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_03435 310fb1a83a645fc48a6518652eeaf22f 580 Pfam PF13382 Adenine deaminase C-terminal domain 416 571 1.1E-34 T 11-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 UP12_03435 310fb1a83a645fc48a6518652eeaf22f 580 SUPERFAMILY SSF51556 82 328 2.19E-8 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_03435 310fb1a83a645fc48a6518652eeaf22f 580 Pfam PF01979 Amidohydrolase family 78 360 1.0E-20 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UP12_03435 310fb1a83a645fc48a6518652eeaf22f 580 SUPERFAMILY SSF51338 20 356 2.68E-16 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_05005 1695fae172463fdde7fc9c31a0efe708 499 Gene3D G3DSA:3.80.30.20 131 489 1.6E-66 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe UP12_05005 1695fae172463fdde7fc9c31a0efe708 499 Pfam PF04055 Radical SAM superfamily 179 350 3.7E-17 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_05005 1695fae172463fdde7fc9c31a0efe708 499 SUPERFAMILY SSF102114 166 482 1.57E-69 T 11-10-2018 UP12_05005 1695fae172463fdde7fc9c31a0efe708 499 SMART SM00729 171 395 3.0E-45 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_05005 1695fae172463fdde7fc9c31a0efe708 499 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 89 489 3.3E-149 T 11-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ UP12_09065 4810fbe4adc53e6e0b2c91506b9d49a3 152 SUPERFAMILY SSF55804 8 143 3.66E-30 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_09065 4810fbe4adc53e6e0b2c91506b9d49a3 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 143 7.4E-30 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_09065 4810fbe4adc53e6e0b2c91506b9d49a3 152 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 129 1.9E-31 T 11-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 UP12_09065 4810fbe4adc53e6e0b2c91506b9d49a3 152 Gene3D G3DSA:3.40.930.10 1 148 3.7E-35 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_09080 2b8c0b7a332f0d3ae40aa9aa98f50aba 258 Pfam PF01418 Helix-turn-helix domain, rpiR family 12 75 2.3E-16 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_09080 2b8c0b7a332f0d3ae40aa9aa98f50aba 258 SUPERFAMILY SSF53697 96 256 1.09E-29 T 11-10-2018 UP12_09080 2b8c0b7a332f0d3ae40aa9aa98f50aba 258 SUPERFAMILY SSF46689 5 75 2.69E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_09080 2b8c0b7a332f0d3ae40aa9aa98f50aba 258 Gene3D G3DSA:3.40.50.10490 92 258 1.4E-30 T 11-10-2018 UP12_09080 2b8c0b7a332f0d3ae40aa9aa98f50aba 258 Gene3D G3DSA:1.10.10.10 5 79 1.4E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09080 2b8c0b7a332f0d3ae40aa9aa98f50aba 258 Pfam PF01380 SIS domain 122 221 9.0E-14 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_11435 99307847af929f140b37cbade2396353 609 Pfam PF10410 DnaB-helicase binding domain of primase 373 426 1.3E-9 T 11-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 UP12_11435 99307847af929f140b37cbade2396353 609 Pfam PF13155 Toprim-like 267 352 2.5E-19 T 11-10-2018 UP12_11435 99307847af929f140b37cbade2396353 609 Gene3D G3DSA:3.40.1360.10 246 370 3.1E-38 T 11-10-2018 UP12_11435 99307847af929f140b37cbade2396353 609 Gene3D G3DSA:3.90.580.10 1 101 1.4E-41 T 11-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 UP12_11435 99307847af929f140b37cbade2396353 609 SUPERFAMILY SSF48024 469 569 3.27E-9 T 11-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 UP12_11435 99307847af929f140b37cbade2396353 609 Pfam PF08275 DNA primase catalytic core, N-terminal domain 130 256 1.4E-45 T 11-10-2018 IPR013264 DNA primase, catalytic core, N-terminal UP12_11435 99307847af929f140b37cbade2396353 609 Gene3D G3DSA:3.90.980.10 114 245 3.5E-53 T 11-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily UP12_11435 99307847af929f140b37cbade2396353 609 Hamap MF_00974 DNA primase [dnaG]. 4 599 30.014 T 11-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 UP12_11435 99307847af929f140b37cbade2396353 609 Pfam PF01807 CHC2 zinc finger 6 99 1.3E-38 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 UP12_11435 99307847af929f140b37cbade2396353 609 Gene3D G3DSA:1.10.860.10 473 569 5.7E-30 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal UP12_11435 99307847af929f140b37cbade2396353 609 SUPERFAMILY SSF57783 4 99 2.55E-36 T 11-10-2018 UP12_11435 99307847af929f140b37cbade2396353 609 SMART SM00400 36 90 1.0E-34 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 UP12_11435 99307847af929f140b37cbade2396353 609 TIGRFAM TIGR01391 dnaG: DNA primase 4 421 5.5E-151 T 11-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 UP12_11435 99307847af929f140b37cbade2396353 609 PIRSF PIRSF002811 2 609 2.8E-200 T 11-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 UP12_11435 99307847af929f140b37cbade2396353 609 SUPERFAMILY SSF56731 119 428 2.35E-103 T 11-10-2018 UP12_11435 99307847af929f140b37cbade2396353 609 SMART SM00493 264 335 2.9E-17 T 11-10-2018 IPR006171 TOPRIM domain UP12_19015 0c3b6dddd594615e34947dbdfd7bde4a 244 Gene3D G3DSA:3.40.50.1820 6 243 2.8E-48 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_19015 0c3b6dddd594615e34947dbdfd7bde4a 244 Pfam PF00756 Putative esterase 15 238 3.2E-24 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 UP12_19015 0c3b6dddd594615e34947dbdfd7bde4a 244 SUPERFAMILY SSF53474 13 241 3.7E-43 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_16930 7312f4f599af103f86a85330b23bb2c6 256 Gene3D G3DSA:3.30.1330.80 22 238 2.9E-83 T 11-10-2018 UP12_16930 7312f4f599af103f86a85330b23bb2c6 256 PIRSF PIRSF001332 6 252 9.8E-98 T 11-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 UP12_16930 7312f4f599af103f86a85330b23bb2c6 256 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 21 251 1.1E-100 T 11-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 UP12_16930 7312f4f599af103f86a85330b23bb2c6 256 Pfam PF03306 Alpha-acetolactate decarboxylase 22 239 3.1E-85 T 11-10-2018 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939 UP12_16930 7312f4f599af103f86a85330b23bb2c6 256 SUPERFAMILY SSF117856 21 251 2.62E-85 T 11-10-2018 UP12_16930 7312f4f599af103f86a85330b23bb2c6 256 Gene3D G3DSA:3.30.1330.80 97 219 2.9E-83 T 11-10-2018 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 SUPERFAMILY SSF52283 25 126 3.78E-32 T 11-10-2018 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 SUPERFAMILY SSF51735 95 279 3.8E-61 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 Gene3D G3DSA:3.40.50.720 91 280 7.8E-114 T 11-10-2018 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 307 1.3E-33 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 SUPERFAMILY SSF55021 440 522 9.82E-21 T 11-10-2018 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 Pfam PF01842 ACT domain 453 512 1.8E-9 T 11-10-2018 IPR002912 ACT domain UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 Gene3D G3DSA:3.30.70.260 451 524 3.1E-23 T 11-10-2018 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 Gene3D G3DSA:3.30.1330.90 317 450 8.3E-32 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 SUPERFAMILY SSF143548 316 446 1.83E-31 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 278 1.8E-62 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 Gene3D G3DSA:3.40.50.720 4 289 7.8E-114 T 11-10-2018 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 524 1.6E-219 T 11-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 UP12_10375 d6df8dcf6ad9b8b853c0a5dc66180132 524 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 141 168 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UP12_00015 96378828597d37ea88f85ce9ac05d848 71 Pfam PF13275 S4 domain 5 69 1.8E-28 T 11-10-2018 UP12_00015 96378828597d37ea88f85ce9ac05d848 71 SUPERFAMILY SSF55174 4 68 3.24E-18 T 11-10-2018 UP12_00015 96378828597d37ea88f85ce9ac05d848 71 Gene3D G3DSA:3.10.290.10 2 70 2.3E-24 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_00015 96378828597d37ea88f85ce9ac05d848 71 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 5 63 1.1E-30 T 11-10-2018 IPR014330 RNA-binding S4-related,YaaA UP12_09805 8f487d13ade98f741f10231fff760802 144 Gene3D G3DSA:3.40.30.10 25 144 1.1E-53 T 11-10-2018 UP12_09805 8f487d13ade98f741f10231fff760802 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 4.6E-64 T 11-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family UP12_09805 8f487d13ade98f741f10231fff760802 144 Pfam PF06491 Disulphide isomerase 8 144 1.6E-61 T 11-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family UP12_05390 817c13bfaea7f65d89ec337a97bad5ff 122 Hamap MF_01536 UPF0344 protein . 2 122 15.801 T 11-10-2018 IPR010899 Protein of unknown function UPF0344 UP12_05390 817c13bfaea7f65d89ec337a97bad5ff 122 Pfam PF07457 Protein of unknown function (DUF1516) 3 112 1.7E-34 T 11-10-2018 IPR010899 Protein of unknown function UPF0344 UP12_05390 817c13bfaea7f65d89ec337a97bad5ff 122 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 3 122 1.0E-26 T 11-10-2018 IPR010899 Protein of unknown function UPF0344 UP12_01735 6b784efb638ae7352018a716e3a84fe6 288 Gene3D G3DSA:3.30.70.1410 121 204 2.6E-30 T 11-10-2018 UP12_01735 6b784efb638ae7352018a716e3a84fe6 288 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 20 276 1.1E-25 T 11-10-2018 IPR006380 Sucrose-phosphatase-like, N-terminal UP12_01735 6b784efb638ae7352018a716e3a84fe6 288 SUPERFAMILY SSF56784 17 279 9.67E-27 T 11-10-2018 IPR036412 HAD-like superfamily UP12_01735 6b784efb638ae7352018a716e3a84fe6 288 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 21 248 4.3E-17 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_07535 4c34780b94e32b4fdebb88731050526d 442 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 418 1.1E-132 T 11-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 UP12_07535 4c34780b94e32b4fdebb88731050526d 442 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 340 360 - T 11-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 UP12_07535 4c34780b94e32b4fdebb88731050526d 442 Pfam PF00860 Permease family 19 393 1.0E-107 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 UP12_07570 30daca88e3a5b4c4424e919cddb51aab 234 SMART SM00934 4 229 6.6E-86 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07570 30daca88e3a5b4c4424e919cddb51aab 234 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 228 5.1E-46 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07570 30daca88e3a5b4c4424e919cddb51aab 234 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 5 229 1.2E-61 T 11-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07570 30daca88e3a5b4c4424e919cddb51aab 234 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 39.016 T 11-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07570 30daca88e3a5b4c4424e919cddb51aab 234 Gene3D G3DSA:3.20.20.70 4 234 2.8E-78 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_07570 30daca88e3a5b4c4424e919cddb51aab 234 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 11-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07570 30daca88e3a5b4c4424e919cddb51aab 234 SUPERFAMILY SSF51366 2 233 2.06E-67 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_08740 e90332e4f16e072aa9cea22256b40001 48 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 48 18.465 T 11-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 UP12_08740 e90332e4f16e072aa9cea22256b40001 48 Pfam PF08179 Small acid-soluble spore protein P family 1 43 1.5E-25 T 11-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 244 264 2.0E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 122 136 2.0E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 380 391 2.0E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 202 224 2.0E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 SMART SM00839 213 454 2.9E-90 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 65 193 1.7E-52 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 211 454 4.6E-89 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 Gene3D G3DSA:3.40.50.720 218 381 5.5E-168 T 11-10-2018 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 Gene3D G3DSA:1.10.285.10 14 391 5.5E-168 T 11-10-2018 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 Gene3D G3DSA:1.10.285.10 392 456 7.4E-10 T 11-10-2018 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 SUPERFAMILY SSF51735 211 455 7.56E-74 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 PIRSF PIRSF000185 29 456 2.0E-126 T 11-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 Gene3D G3DSA:3.40.50.10860 63 198 5.5E-168 T 11-10-2018 UP12_18020 32d5c5aa47e8eba6c118e9bc8993e616 456 SUPERFAMILY SSF53223 14 205 4.8E-76 T 11-10-2018 UP12_03350 9658848ae6b8353907633f291dd20f96 240 Pfam PF01259 SAICAR synthetase 8 232 2.7E-69 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03350 9658848ae6b8353907633f291dd20f96 240 Gene3D G3DSA:3.30.200.20 8 233 7.9E-100 T 11-10-2018 UP12_03350 9658848ae6b8353907633f291dd20f96 240 ProSitePatterns PS01057 SAICAR synthetase signature 1. 87 101 - T 11-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03350 9658848ae6b8353907633f291dd20f96 240 Gene3D G3DSA:3.30.470.20 86 222 7.9E-100 T 11-10-2018 UP12_03350 9658848ae6b8353907633f291dd20f96 240 SUPERFAMILY SSF56104 4 238 2.84E-84 T 11-10-2018 UP12_03350 9658848ae6b8353907633f291dd20f96 240 ProSitePatterns PS01058 SAICAR synthetase signature 2. 174 182 - T 11-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03350 9658848ae6b8353907633f291dd20f96 240 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 5 236 33.226 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03350 9658848ae6b8353907633f291dd20f96 240 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 1 239 3.1E-85 T 11-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 Pfam PF00667 FAD binding domain 234 429 8.0E-30 T 11-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 SUPERFAMILY SSF63380 232 452 8.97E-62 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 SUPERFAMILY SSF52343 451 606 1.83E-51 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 7 606 1.8E-263 T 11-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 Pfam PF00175 Oxidoreductase NAD-binding domain 464 570 5.3E-17 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 Gene3D G3DSA:3.40.50.80 452 606 1.2E-58 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PIRSF PIRSF000207 1 606 1.3E-274 T 11-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 Gene3D G3DSA:3.40.50.360 59 220 4.3E-49 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 Pfam PF00258 Flavodoxin 70 201 3.8E-30 T 11-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 SUPERFAMILY SSF52218 66 209 3.64E-47 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00369 Flavodoxin signature 173 192 1.2E-13 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00369 Flavodoxin signature 69 82 1.2E-13 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00369 Flavodoxin signature 117 128 1.2E-13 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00369 Flavodoxin signature 149 159 1.2E-13 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 Gene3D G3DSA:1.20.990.10 282 391 5.1E-73 T 11-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 Gene3D G3DSA:2.40.30.10 234 446 5.1E-73 T 11-10-2018 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 532 548 1.7E-28 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 272 282 1.7E-28 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 488 497 1.7E-28 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 393 400 1.7E-28 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 555 563 1.7E-28 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 501 512 1.7E-28 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_09110 3d4aa0ff1fad6f997bcd829f6f24cf50 606 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 463 482 1.7E-28 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 UP12_15405 14c0d726608e9ca6cf3b18b45a54aba4 273 Pfam PF03180 NLPA lipoprotein 32 271 1.8E-84 T 11-10-2018 IPR004872 Lipoprotein NlpA family UP12_15405 14c0d726608e9ca6cf3b18b45a54aba4 273 Gene3D G3DSA:3.40.190.10 34 270 1.6E-95 T 11-10-2018 UP12_15405 14c0d726608e9ca6cf3b18b45a54aba4 273 SUPERFAMILY SSF53850 31 271 7.47E-75 T 11-10-2018 UP12_15405 14c0d726608e9ca6cf3b18b45a54aba4 273 PIRSF PIRSF002854 1 272 6.0E-91 T 11-10-2018 IPR004872 Lipoprotein NlpA family UP12_15405 14c0d726608e9ca6cf3b18b45a54aba4 273 Gene3D G3DSA:3.40.190.10 114 221 1.6E-95 T 11-10-2018 UP12_09655 3937472131c3d95165a6fe60ae2d0e12 74 Pfam PF06855 YozE SAM-like fold 3 68 1.1E-25 T 11-10-2018 IPR023089 YozE SAM-like domain UP12_09655 3937472131c3d95165a6fe60ae2d0e12 74 Hamap MF_01538 UPF0346 protein . 1 70 20.819 T 11-10-2018 IPR010673 Protein of unknown function UPF0346 UP12_09655 3937472131c3d95165a6fe60ae2d0e12 74 Gene3D G3DSA:1.10.150.260 1 72 8.9E-27 T 11-10-2018 IPR036806 YozE SAM-like superfamily UP12_09655 3937472131c3d95165a6fe60ae2d0e12 74 PIRSF PIRSF037262 1 72 7.3E-33 T 11-10-2018 IPR010673 Protein of unknown function UPF0346 UP12_09655 3937472131c3d95165a6fe60ae2d0e12 74 SUPERFAMILY SSF140652 2 72 4.32E-28 T 11-10-2018 IPR036806 YozE SAM-like superfamily UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 SUPERFAMILY SSF46894 152 227 2.07E-24 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 SUPERFAMILY SSF52172 3 136 2.28E-34 T 11-10-2018 IPR011006 CheY-like superfamily UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 SMART SM00448 4 117 9.1E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 Gene3D G3DSA:3.40.50.12740 4 226 6.2E-70 T 11-10-2018 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 1.0E-14 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 1.0E-14 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 1.0E-14 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 165 220 7.9E-25 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 Pfam PF00072 Response regulator receiver domain 6 118 5.3E-32 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 ProSitePatterns PS00622 LuxR-type HTH domain signature. 180 207 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_16600 6471c5abe4c44d0ce3e0ae3f1774b8a5 229 SMART SM00421 163 220 9.7E-29 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 SUPERFAMILY SSF52794 171 273 1.92E-37 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 147 3.7E-40 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_06975 2323e9c36617df633eeb75542b63cd40 630 Gene3D G3DSA:3.40.930.10 1 150 1.3E-48 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 Gene3D G3DSA:3.40.50.2300 160 272 1.9E-42 T 11-10-2018 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 Pfam PF02378 Phosphotransferase system, EIIC 301 570 7.7E-10 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_06975 2323e9c36617df633eeb75542b63cd40 630 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 285 623 1.8E-131 T 11-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 174 263 3.7E-17 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 9.6E-39 T 11-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 174 255 8.8E-31 T 11-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 UP12_06975 2323e9c36617df633eeb75542b63cd40 630 SUPERFAMILY SSF55804 1 147 3.01E-42 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_06635 107fd6f1e568b47b4036be75b5608277 243 Pfam PF04055 Radical SAM superfamily 29 125 2.6E-13 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_06635 107fd6f1e568b47b4036be75b5608277 243 Gene3D G3DSA:3.20.20.70 5 236 1.2E-31 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_06635 107fd6f1e568b47b4036be75b5608277 243 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 4 243 1.5E-115 T 11-10-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 UP12_06635 107fd6f1e568b47b4036be75b5608277 243 SUPERFAMILY SSF102114 27 167 5.49E-14 T 11-10-2018 UP12_06635 107fd6f1e568b47b4036be75b5608277 243 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 240 36.664 T 11-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 UP12_06635 107fd6f1e568b47b4036be75b5608277 243 PIRSF PIRSF000370 3 243 6.3E-52 T 11-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 UP12_06635 107fd6f1e568b47b4036be75b5608277 243 Pfam PF13394 4Fe-4S single cluster domain 27 115 1.5E-10 T 11-10-2018 UP12_17815 2ff034219f53b61ff97ca69a8edc054e 319 SUPERFAMILY SSF81464 22 121 2.13E-23 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17815 2ff034219f53b61ff97ca69a8edc054e 319 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 42 113 4.3E-9 T 11-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17815 2ff034219f53b61ff97ca69a8edc054e 319 Gene3D G3DSA:2.60.40.420 118 278 3.8E-41 T 11-10-2018 IPR008972 Cupredoxin UP12_17815 2ff034219f53b61ff97ca69a8edc054e 319 SUPERFAMILY SSF49503 127 278 9.49E-42 T 11-10-2018 IPR008972 Cupredoxin UP12_17815 2ff034219f53b61ff97ca69a8edc054e 319 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 15 243 1.1E-125 T 11-10-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 UP12_17815 2ff034219f53b61ff97ca69a8edc054e 319 Gene3D G3DSA:1.10.287.90 30 117 2.2E-29 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17815 2ff034219f53b61ff97ca69a8edc054e 319 PIRSF PIRSF000292 5 314 1.8E-110 T 11-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 11-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 290 1.1E-81 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 PIRSF PIRSF005917 3 292 5.6E-100 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 Gene3D G3DSA:3.40.1010.10 1 122 6.1E-44 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 SUPERFAMILY SSF53790 13 231 6.02E-80 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 Gene3D G3DSA:3.30.950.10 123 238 2.4E-41 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 213 2.9E-26 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 UP12_00245 38bc374108d5407c9adf3c91f2c32b52 292 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 35.739 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 Pfam PF01235 Sodium:alanine symporter family 55 450 2.2E-151 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 438 1.2E-150 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 PRINTS PR00175 Sodium/alanine symporter signature 302 320 2.1E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 PRINTS PR00175 Sodium/alanine symporter signature 211 230 2.1E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 PRINTS PR00175 Sodium/alanine symporter signature 347 369 2.1E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 PRINTS PR00175 Sodium/alanine symporter signature 183 201 2.1E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 PRINTS PR00175 Sodium/alanine symporter signature 407 427 2.1E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11860 bf9d3fea4428a865fb34225473942e59 483 PRINTS PR00175 Sodium/alanine symporter signature 93 115 2.1E-55 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_11235 4724179e5b7907a8c1c11f06448aeded 417 Gene3D G3DSA:1.20.1250.20 8 396 4.9E-22 T 11-10-2018 UP12_11235 4724179e5b7907a8c1c11f06448aeded 417 SUPERFAMILY SSF103473 11 400 2.22E-29 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_11235 4724179e5b7907a8c1c11f06448aeded 417 Pfam PF07690 Major Facilitator Superfamily 38 360 6.5E-14 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_09700 67e270f7ecb8a7646c6aada76d981be2 342 Gene3D G3DSA:3.90.25.30 178 320 1.8E-119 T 11-10-2018 UP12_09700 67e270f7ecb8a7646c6aada76d981be2 342 Gene3D G3DSA:3.40.50.720 15 316 1.8E-119 T 11-10-2018 UP12_09700 67e270f7ecb8a7646c6aada76d981be2 342 SUPERFAMILY SSF51735 15 276 7.23E-56 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_09700 67e270f7ecb8a7646c6aada76d981be2 342 Pfam PF02719 Polysaccharide biosynthesis protein 18 297 1.3E-102 T 11-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain UP12_14675 00b2ea13fee740d38e36eb29ad6b8fd8 125 Gene3D G3DSA:1.10.260.40 4 116 4.7E-18 T 11-10-2018 UP12_14675 00b2ea13fee740d38e36eb29ad6b8fd8 125 SUPERFAMILY SSF47413 3 69 5.09E-14 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_14675 00b2ea13fee740d38e36eb29ad6b8fd8 125 Pfam PF01381 Helix-turn-helix 11 64 2.6E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_14675 00b2ea13fee740d38e36eb29ad6b8fd8 125 SMART SM00530 8 64 2.0E-12 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_02880 45c400241daaf81eedd6303dd40416d7 479 SUPERFAMILY SSF103473 8 472 2.09E-55 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_02880 45c400241daaf81eedd6303dd40416d7 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 440 3.6E-97 T 11-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UP12_02880 45c400241daaf81eedd6303dd40416d7 479 Pfam PF07690 Major Facilitator Superfamily 21 412 1.2E-39 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_02880 45c400241daaf81eedd6303dd40416d7 479 Gene3D G3DSA:1.20.1720.10 16 224 3.3E-34 T 11-10-2018 UP12_02880 45c400241daaf81eedd6303dd40416d7 479 Gene3D G3DSA:1.20.1250.20 265 477 3.8E-21 T 11-10-2018 UP12_00155 4f654a6fa9f5704e8732eecb387b8ca9 87 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 6 86 4.1E-23 T 11-10-2018 IPR010001 SigmaK-factor processing regulatory BofA UP12_00155 4f654a6fa9f5704e8732eecb387b8ca9 87 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 13 83 7.0E-19 T 11-10-2018 IPR010001 SigmaK-factor processing regulatory BofA UP12_08475 d03355647aeaf49a9018e7d9cee548eb 252 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 4 172 5.0E-44 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_08475 d03355647aeaf49a9018e7d9cee548eb 252 SUPERFAMILY SSF53187 1 178 1.0E-50 T 11-10-2018 UP12_08475 d03355647aeaf49a9018e7d9cee548eb 252 Pfam PF05036 Sporulation related domain 182 251 5.2E-18 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 UP12_08475 d03355647aeaf49a9018e7d9cee548eb 252 SMART SM00646 64 172 4.0E-44 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_08475 d03355647aeaf49a9018e7d9cee548eb 252 SUPERFAMILY SSF110997 181 251 7.45E-18 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 UP12_08475 d03355647aeaf49a9018e7d9cee548eb 252 Gene3D G3DSA:3.40.630.40 1 174 2.0E-53 T 11-10-2018 UP12_08475 d03355647aeaf49a9018e7d9cee548eb 252 Gene3D G3DSA:3.30.70.1070 183 252 1.3E-26 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 UP12_07665 b1acc2a78265897a20b4376e803b44be 447 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 323 334 - T 11-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 UP12_07665 b1acc2a78265897a20b4376e803b44be 447 SUPERFAMILY SSF48013 3 130 4.19E-37 T 11-10-2018 IPR035926 NusB-like superfamily UP12_07665 b1acc2a78265897a20b4376e803b44be 447 Pfam PF01029 NusB family 5 128 1.1E-31 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UP12_07665 b1acc2a78265897a20b4376e803b44be 447 Pfam PF01189 16S rRNA methyltransferase RsmB/F 245 443 1.0E-61 T 11-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 UP12_07665 b1acc2a78265897a20b4376e803b44be 447 Gene3D G3DSA:3.40.50.150 145 445 6.9E-87 T 11-10-2018 UP12_07665 b1acc2a78265897a20b4376e803b44be 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 324 336 1.9E-31 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UP12_07665 b1acc2a78265897a20b4376e803b44be 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 374 390 1.9E-31 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UP12_07665 b1acc2a78265897a20b4376e803b44be 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 256 266 1.9E-31 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UP12_07665 b1acc2a78265897a20b4376e803b44be 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 227 241 1.9E-31 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UP12_07665 b1acc2a78265897a20b4376e803b44be 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 1.9E-31 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase UP12_07665 b1acc2a78265897a20b4376e803b44be 447 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 447 4.5E-185 T 11-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 UP12_07665 b1acc2a78265897a20b4376e803b44be 447 SUPERFAMILY SSF53335 138 446 1.53E-76 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_07665 b1acc2a78265897a20b4376e803b44be 447 Gene3D G3DSA:1.10.940.10 1 142 3.5E-41 T 11-10-2018 IPR035926 NusB-like superfamily UP12_15085 23d559e0903d16a8185727c243a76840 198 PIRSF PIRSF016661 1 191 6.3E-42 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UP12_15085 23d559e0903d16a8185727c243a76840 198 Pfam PF02632 BioY family 36 181 2.0E-30 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UP12_15085 23d559e0903d16a8185727c243a76840 198 Gene3D G3DSA:1.10.1760.20 1 191 3.7E-45 T 11-10-2018 UP12_17735 ac8f86a3f3ace37a68bf503f220d1503 101 Pfam PF11181 Heat induced stress protein YflT 5 98 1.1E-13 T 11-10-2018 IPR025889 General stress protein 17M-like domain UP12_16435 5bfeb4764661ef9397f6e6026a5c8bf0 121 Gene3D G3DSA:1.10.10.10 4 119 1.5E-40 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16435 5bfeb4764661ef9397f6e6026a5c8bf0 121 Pfam PF01638 HxlR-like helix-turn-helix 23 111 1.5E-38 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_16435 5bfeb4764661ef9397f6e6026a5c8bf0 121 SUPERFAMILY SSF46785 10 110 9.1E-34 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_00270 88629fb2edca50e122076d63d5189baa 186 Pfam PF13662 Toprim domain 4 71 5.1E-6 T 11-10-2018 IPR006171 TOPRIM domain UP12_00270 88629fb2edca50e122076d63d5189baa 186 SUPERFAMILY SSF110455 1 114 1.28E-34 T 11-10-2018 UP12_00270 88629fb2edca50e122076d63d5189baa 186 Gene3D G3DSA:3.40.1360.20 1 117 4.2E-25 T 11-10-2018 UP12_00270 88629fb2edca50e122076d63d5189baa 186 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 2 177 4.4E-68 T 11-10-2018 IPR004466 Ribonuclease M5 GO:0043822 UP12_00270 88629fb2edca50e122076d63d5189baa 186 Hamap MF_01469 Ribonuclease M5 [rnmV]. 3 178 32.083 T 11-10-2018 IPR004466 Ribonuclease M5 GO:0043822 UP12_00270 88629fb2edca50e122076d63d5189baa 186 SMART SM00493 4 77 1.1E-6 T 11-10-2018 IPR006171 TOPRIM domain UP12_00270 88629fb2edca50e122076d63d5189baa 186 Pfam PF13331 Domain of unknown function (DUF4093) 93 176 1.6E-27 T 11-10-2018 IPR025156 Ribonuclease M5, C-terminal domain UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 SMART SM00359 282 363 9.2E-10 T 11-10-2018 IPR002478 PUA domain GO:0003723 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 SUPERFAMILY SSF88697 282 342 1.89E-13 T 11-10-2018 IPR015947 PUA-like superfamily UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 Gene3D G3DSA:2.30.130.10 271 366 2.6E-18 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 Pfam PF00696 Amino acid kinase family 8 225 1.9E-41 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 Pfam PF01472 PUA domain 282 355 2.9E-13 T 11-10-2018 IPR002478 PUA domain GO:0003723 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 Hamap MF_00456 Glutamate 5-kinase [proB]. 8 268 37.317 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 PRINTS PR00474 Glutamate 5-kinase family signature 212 232 2.5E-52 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 PRINTS PR00474 Glutamate 5-kinase family signature 119 140 2.5E-52 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 PRINTS PR00474 Glutamate 5-kinase family signature 45 59 2.5E-52 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 PRINTS PR00474 Glutamate 5-kinase family signature 79 107 2.5E-52 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 PRINTS PR00474 Glutamate 5-kinase family signature 151 178 2.5E-52 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 PIRSF PIRSF000729 3 367 2.1E-133 T 11-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 SUPERFAMILY SSF53633 8 259 2.09E-67 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 TIGRFAM TIGR01027 proB: glutamate 5-kinase 8 358 1.3E-125 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_09335 06e8f9f29466b6013dd5533b9d836c24 372 Gene3D G3DSA:3.40.1160.10 3 265 3.2E-85 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_05770 bb2012f26e2f83e1d63d8f6736665929 255 Pfam PF01464 Transglycosylase SLT domain 139 245 1.9E-29 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 UP12_05770 bb2012f26e2f83e1d63d8f6736665929 255 SUPERFAMILY SSF53955 135 253 8.45E-46 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_05770 bb2012f26e2f83e1d63d8f6736665929 255 Gene3D G3DSA:1.10.530.10 97 255 6.4E-49 T 11-10-2018 UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 Gene3D G3DSA:1.20.5.170 246 290 2.6E-20 T 11-10-2018 UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 Pfam PF10388 EAL-domain associated signalling protein domain 240 406 1.4E-79 T 11-10-2018 IPR018842 YkuI, C-terminal UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 Gene3D G3DSA:3.30.450.20 291 406 1.6E-45 T 11-10-2018 UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 Gene3D G3DSA:3.20.20.450 1 229 1.2E-65 T 11-10-2018 IPR035919 EAL domain superfamily UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 Pfam PF00563 EAL domain 13 236 4.0E-29 T 11-10-2018 IPR001633 EAL domain UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 SMART SM00052 1 241 1.3E-39 T 11-10-2018 IPR001633 EAL domain UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 SUPERFAMILY SSF103190 263 404 1.41E-44 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_06815 bd34b74b9876e6ec7496b65da70db149 406 SUPERFAMILY SSF141868 7 237 5.75E-45 T 11-10-2018 IPR035919 EAL domain superfamily UP12_08580 7bb6468c5e9adf57d1180b8ff1a62463 621 Gene3D G3DSA:3.30.470.30 1 207 7.8E-38 T 11-10-2018 UP12_08580 7bb6468c5e9adf57d1180b8ff1a62463 621 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 12 591 8.8E-173 T 11-10-2018 IPR014143 DNA ligase D UP12_08580 7bb6468c5e9adf57d1180b8ff1a62463 621 SUPERFAMILY SSF56091 4 207 1.9E-31 T 11-10-2018 UP12_08580 7bb6468c5e9adf57d1180b8ff1a62463 621 Pfam PF01068 ATP dependent DNA ligase domain 15 207 1.5E-30 T 11-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 UP12_08580 7bb6468c5e9adf57d1180b8ff1a62463 621 Gene3D G3DSA:3.90.920.30 330 605 4.3E-79 T 11-10-2018 UP12_08580 7bb6468c5e9adf57d1180b8ff1a62463 621 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 323 563 9.9E-85 T 11-10-2018 IPR014145 DNA ligase D, polymerase domain UP12_18720 c5ba74648418ec02f292e476c0298249 236 SMART SM00866 87 226 5.5E-27 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_18720 c5ba74648418ec02f292e476c0298249 236 Pfam PF07702 UTRA domain 91 221 6.7E-26 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_18720 c5ba74648418ec02f292e476c0298249 236 Gene3D G3DSA:1.10.10.10 1 70 1.9E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18720 c5ba74648418ec02f292e476c0298249 236 SMART SM00345 7 66 7.3E-13 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_18720 c5ba74648418ec02f292e476c0298249 236 SUPERFAMILY SSF64288 54 230 2.51E-37 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_18720 c5ba74648418ec02f292e476c0298249 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 2.9E-14 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_18720 c5ba74648418ec02f292e476c0298249 236 Gene3D G3DSA:3.40.1410.10 71 235 2.5E-38 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_18720 c5ba74648418ec02f292e476c0298249 236 SUPERFAMILY SSF46785 5 75 1.07E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_00795 76db736b3b103ad262ccf5b59c773fc7 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 32.851 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00795 76db736b3b103ad262ccf5b59c773fc7 132 Gene3D G3DSA:3.30.1370.30 4 74 8.6E-33 T 11-10-2018 UP12_00795 76db736b3b103ad262ccf5b59c773fc7 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00795 76db736b3b103ad262ccf5b59c773fc7 132 Pfam PF00410 Ribosomal protein S8 5 132 4.4E-54 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00795 76db736b3b103ad262ccf5b59c773fc7 132 SUPERFAMILY SSF56047 2 132 5.23E-49 T 11-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00795 76db736b3b103ad262ccf5b59c773fc7 132 Gene3D G3DSA:3.30.1490.10 75 132 9.1E-27 T 11-10-2018 UP12_12560 01fa9cfff0591e4f1b890d1a6b4d62e9 269 Gene3D G3DSA:3.40.630.40 1 179 2.0E-53 T 11-10-2018 UP12_12560 01fa9cfff0591e4f1b890d1a6b4d62e9 269 SMART SM00646 64 176 3.2E-38 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_12560 01fa9cfff0591e4f1b890d1a6b4d62e9 269 SUPERFAMILY SSF53187 3 180 1.0E-49 T 11-10-2018 UP12_12560 01fa9cfff0591e4f1b890d1a6b4d62e9 269 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 5 176 1.7E-45 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 Pfam PF01170 Putative RNA methylase family UPF0020 164 368 5.0E-66 T 11-10-2018 IPR000241 Putative RNA methylase domain UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 197 208 - T 11-10-2018 IPR000241 Putative RNA methylase domain UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 SMART SM00981 57 156 1.5E-11 T 11-10-2018 IPR004114 THUMP domain GO:0003723 UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 Gene3D G3DSA:3.30.2130.30 8 247 4.4E-125 T 11-10-2018 UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 SUPERFAMILY SSF53335 145 362 9.71E-40 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 301 307 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 Gene3D G3DSA:3.40.50.150 162 367 4.4E-125 T 11-10-2018 UP12_09940 766954cc6ff07166c5a50b306b688fe6 384 Pfam PF02926 THUMP domain 18 155 1.1E-16 T 11-10-2018 IPR004114 THUMP domain GO:0003723 UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 SUPERFAMILY SSF51735 4 230 1.79E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.2E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.2E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 Pfam PF00106 short chain dehydrogenase 8 190 3.3E-33 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 3.7E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.7E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 3.7E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06235 be6c01729bb7676cdf13821a9eb49917 231 Gene3D G3DSA:3.40.50.720 1 230 1.5E-45 T 11-10-2018 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 SUPERFAMILY SSF47781 463 550 4.22E-26 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Pfam PF09371 Tex-like protein N-terminal domain 11 193 2.1E-69 T 11-10-2018 IPR018974 Tex-like protein, N-terminal UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Pfam PF12836 Helix-hairpin-helix motif 484 548 3.7E-25 T 11-10-2018 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 SUPERFAMILY SSF50249 631 717 1.42E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 SMART SM00732 319 417 3.5E-36 T 11-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 SMART SM00316 645 716 3.8E-23 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 SUPERFAMILY SSF53098 315 462 5.23E-51 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 SUPERFAMILY SSF158832 8 314 2.62E-113 T 11-10-2018 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Gene3D G3DSA:2.40.50.140 631 717 7.9E-25 T 11-10-2018 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 SUPERFAMILY SSF47781 554 628 2.45E-15 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Pfam PF16921 Tex protein YqgF-like domain 319 444 2.8E-56 T 11-10-2018 IPR032639 Tex protein, YqgF-like domain UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Gene3D G3DSA:1.10.10.650 4 111 6.8E-38 T 11-10-2018 IPR023319 Tex-like protein, HTH domain superfamily UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Pfam PF00575 S1 RNA binding domain 645 715 5.4E-18 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Gene3D G3DSA:1.10.3500.10 114 491 1.6E-158 T 11-10-2018 IPR023323 Tex-like domain superfamily UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Gene3D G3DSA:3.30.420.140 318 444 1.6E-158 T 11-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 UP12_02590 e329e603d8e2c314fefaf7ba1692426d 719 Gene3D G3DSA:1.10.150.310 492 626 2.2E-44 T 11-10-2018 UP12_12860 325eff926d581b3bb4b9c8c1bd72e216 257 Pfam PF01012 Electron transfer flavoprotein domain 23 206 1.6E-46 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UP12_12860 325eff926d581b3bb4b9c8c1bd72e216 257 SUPERFAMILY SSF52402 1 243 9.21E-74 T 11-10-2018 UP12_12860 325eff926d581b3bb4b9c8c1bd72e216 257 Gene3D G3DSA:3.40.50.620 1 256 6.8E-80 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_12860 325eff926d581b3bb4b9c8c1bd72e216 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 11-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 UP12_12860 325eff926d581b3bb4b9c8c1bd72e216 257 PIRSF PIRSF000090 1 257 1.9E-75 T 11-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 UP12_12860 325eff926d581b3bb4b9c8c1bd72e216 257 SMART SM00893 21 211 1.2E-60 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UP12_11935 bb4aa24f623b15132695a77dfaba5b2c 422 ProSitePatterns PS01276 Peptidase family U32 signature. 179 197 - T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 UP12_11935 bb4aa24f623b15132695a77dfaba5b2c 422 Gene3D G3DSA:2.40.30.10 334 421 3.2E-35 T 11-10-2018 UP12_11935 bb4aa24f623b15132695a77dfaba5b2c 422 Pfam PF01136 Peptidase family U32 93 323 1.2E-85 T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 UP12_11935 bb4aa24f623b15132695a77dfaba5b2c 422 Pfam PF16325 Peptidase family U32 C-terminal domain 339 419 2.2E-24 T 11-10-2018 IPR032525 Peptidase family U32, C-terminal UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 Gene3D G3DSA:1.10.287.990 89 152 2.4E-24 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 159 260 2.8E-33 T 11-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 72 152 2.4E-28 T 11-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 SUPERFAMILY SSF46609 68 153 1.2E-31 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 SUPERFAMILY SSF54719 151 265 6.29E-39 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 Gene3D G3DSA:2.40.500.20 153 271 8.6E-42 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 PRINTS PR01703 Manganese superoxide dismutase signature 75 86 1.8E-21 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 PRINTS PR01703 Manganese superoxide dismutase signature 135 148 1.8E-21 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 PRINTS PR01703 Manganese superoxide dismutase signature 188 196 1.8E-21 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 PRINTS PR01703 Manganese superoxide dismutase signature 226 238 1.8E-21 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 PRINTS PR01703 Manganese superoxide dismutase signature 96 109 1.8E-21 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_09515 a4456907f70bc08244a06ea18d7321aa 273 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 228 235 - T 11-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_02260 d0d7a272716d791dd623c9148d5c9946 263 SUPERFAMILY SSF160920 3 255 1.7E-114 T 11-10-2018 IPR038021 Putative hydro-lyase UP12_02260 d0d7a272716d791dd623c9148d5c9946 263 Gene3D G3DSA:3.30.2040.10 122 234 1.6E-96 T 11-10-2018 UP12_02260 d0d7a272716d791dd623c9148d5c9946 263 Gene3D G3DSA:3.40.1640.10 17 250 1.6E-96 T 11-10-2018 UP12_02260 d0d7a272716d791dd623c9148d5c9946 263 Pfam PF07286 Protein of unknown function (DUF1445) 112 254 1.2E-67 T 11-10-2018 IPR009906 D-glutamate cyclase UP12_02260 d0d7a272716d791dd623c9148d5c9946 263 PIRSF PIRSF029755 1 263 1.7E-125 T 11-10-2018 IPR016938 Uncharacterised protein family UPF0317 UP12_02260 d0d7a272716d791dd623c9148d5c9946 263 Hamap MF_01830 Putative hydro-lyase . 8 262 54.515 T 11-10-2018 IPR016938 Uncharacterised protein family UPF0317 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Pfam PF02872 5'-nucleotidase, C-terminal domain 375 572 1.4E-24 T 11-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Pfam PF02872 5'-nucleotidase, C-terminal domain 976 1138 3.2E-49 T 11-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1388 1420 2.4E-4 T 11-10-2018 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Gene3D G3DSA:3.90.780.10 976 1177 1.5E-68 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 SUPERFAMILY SSF56300 663 972 6.77E-78 T 11-10-2018 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 ProSitePatterns PS00785 5'-nucleotidase signature 1. 45 57 - T 11-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 SUPERFAMILY SSF55816 374 610 1.31E-46 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 SUPERFAMILY SSF56300 41 372 4.32E-81 T 11-10-2018 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Pfam PF00746 LPXTG cell wall anchor motif 1387 1420 8.2E-4 T 11-10-2018 IPR019948 Gram-positive LPXTG cell wall anchor UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 ProSitePatterns PS00785 5'-nucleotidase signature 1. 668 680 - T 11-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Gene3D G3DSA:3.60.21.10 665 974 4.0E-88 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 PRINTS PR01607 Apyrase family signature 1112 1131 4.0E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 PRINTS PR01607 Apyrase family signature 880 903 4.0E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 PRINTS PR01607 Apyrase family signature 911 931 4.0E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 PRINTS PR01607 Apyrase family signature 861 878 4.0E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 PRINTS PR01607 Apyrase family signature 666 684 4.0E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 PRINTS PR01607 Apyrase family signature 1034 1057 4.0E-39 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 ProSitePatterns PS00786 5'-nucleotidase signature 2. 134 145 - T 11-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Pfam PF00149 Calcineurin-like phosphoesterase 46 284 1.7E-14 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Pfam PF00149 Calcineurin-like phosphoesterase 668 897 1.0E-15 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 SUPERFAMILY SSF55816 975 1174 2.62E-60 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Gene3D G3DSA:3.90.780.10 424 609 2.5E-59 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_03975 b1e28667e9198ee6d3d9c4a181482a64 1427 Gene3D G3DSA:3.60.21.10 35 373 1.3E-132 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 SMART SM00304 176 228 5.4E-11 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 SMART SM00387 339 442 3.6E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 SMART SM00388 229 295 1.4E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 Pfam PF00672 HAMP domain 176 224 2.3E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 Gene3D G3DSA:1.10.8.500 175 225 2.2E-7 T 11-10-2018 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 440 5.3E-13 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 6.5E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 6.5E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 6.5E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 439 6.5E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 SUPERFAMILY SSF47384 213 293 8.44E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 Gene3D G3DSA:3.30.565.10 306 442 1.9E-25 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 Gene3D G3DSA:1.10.287.130 226 294 5.3E-15 T 11-10-2018 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 293 1.4E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 SUPERFAMILY SSF158472 176 225 8.63E-9 T 11-10-2018 UP12_15505 779235e89b9ea95330ce2ebc5bf4520b 443 SUPERFAMILY SSF55874 303 440 1.96E-23 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 Pfam PF03466 LysR substrate binding domain 91 287 5.9E-39 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 Gene3D G3DSA:3.40.190.290 92 293 5.0E-44 T 11-10-2018 UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 Gene3D G3DSA:1.10.10.10 3 88 1.4E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.5E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.5E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.5E-9 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 SUPERFAMILY SSF53850 91 290 4.35E-37 T 11-10-2018 UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.6E-18 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03310 66ec9a256df6c34b3b823b1f04d69a74 298 SUPERFAMILY SSF46785 5 111 3.37E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18235 d9a7d484c85baf743b615f22447ea5e2 107 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 2 86 1.1E-15 T 11-10-2018 IPR010310 Type VII secretion system ESAT-6-like UP12_18235 d9a7d484c85baf743b615f22447ea5e2 107 Pfam PF06013 Proteins of 100 residues with WXG 2 80 4.5E-12 T 11-10-2018 IPR010310 Type VII secretion system ESAT-6-like UP12_18235 d9a7d484c85baf743b615f22447ea5e2 107 SUPERFAMILY SSF140453 3 88 1.27E-13 T 11-10-2018 IPR036689 ESAT-6-like superfamily UP12_18235 d9a7d484c85baf743b615f22447ea5e2 107 Gene3D G3DSA:1.10.287.1060 1 88 9.6E-14 T 11-10-2018 UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 Gene3D G3DSA:3.40.50.1220 196 325 1.8E-57 T 11-10-2018 UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 Pfam PF01012 Electron transfer flavoprotein domain 6 179 1.2E-44 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 SMART SM00893 5 195 1.0E-46 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 11-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 SUPERFAMILY SSF52402 3 192 1.05E-50 T 11-10-2018 UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 Gene3D G3DSA:3.40.50.620 1 195 3.4E-57 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 SUPERFAMILY SSF52467 198 318 1.62E-48 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 PIRSF PIRSF000089 1 322 1.9E-115 T 11-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 UP12_12855 75b06f54ac0382fa30a441cb18515b3f 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 5.2E-36 T 11-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 UP12_15635 b1a3bd546475fb53ce04e3b4c12ecd01 350 SUPERFAMILY SSF81345 25 345 9.42E-83 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15635 b1a3bd546475fb53ce04e3b4c12ecd01 350 Pfam PF01032 FecCD transport family 36 345 7.6E-93 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_15635 b1a3bd546475fb53ce04e3b4c12ecd01 350 Gene3D G3DSA:1.10.3470.10 24 349 1.2E-94 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_09490 5ac95799c877fa07ac15a7dc66a4e794 215 Gene3D G3DSA:3.40.50.720 1 215 4.4E-57 T 11-10-2018 UP12_09490 5ac95799c877fa07ac15a7dc66a4e794 215 Pfam PF13460 NAD(P)H-binding 7 191 9.8E-47 T 11-10-2018 IPR016040 NAD(P)-binding domain UP12_09490 5ac95799c877fa07ac15a7dc66a4e794 215 SUPERFAMILY SSF51735 1 203 7.43E-41 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_05920 36ac2dbfa64023d3b7faf5781e3e702f 246 SUPERFAMILY SSF53474 6 237 9.23E-33 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_05920 36ac2dbfa64023d3b7faf5781e3e702f 246 Gene3D G3DSA:3.40.50.1820 2 242 2.2E-44 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_05920 36ac2dbfa64023d3b7faf5781e3e702f 246 Pfam PF00756 Putative esterase 15 238 7.3E-49 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 UP12_15255 9f7c863922b16043899991222b70fea4 457 Pfam PF02872 5'-nucleotidase, C-terminal domain 284 421 1.4E-16 T 11-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 Pfam PF00149 Calcineurin-like phosphoesterase 6 200 9.5E-8 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_15255 9f7c863922b16043899991222b70fea4 457 PIRSF PIRSF036361 1 457 1.5E-177 T 11-10-2018 IPR011240 Phosphoesterase-related protein YunD UP12_15255 9f7c863922b16043899991222b70fea4 457 Gene3D G3DSA:3.60.21.10 1 274 2.1E-57 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_15255 9f7c863922b16043899991222b70fea4 457 SUPERFAMILY SSF56300 4 273 1.94E-67 T 11-10-2018 UP12_15255 9f7c863922b16043899991222b70fea4 457 Gene3D G3DSA:3.90.780.10 276 454 1.3E-17 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 PRINTS PR01607 Apyrase family signature 3 21 1.7E-16 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 PRINTS PR01607 Apyrase family signature 211 231 1.7E-16 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 PRINTS PR01607 Apyrase family signature 183 206 1.7E-16 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 PRINTS PR01607 Apyrase family signature 325 348 1.7E-16 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 PRINTS PR01607 Apyrase family signature 164 181 1.7E-16 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 PRINTS PR01607 Apyrase family signature 407 426 1.7E-16 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_15255 9f7c863922b16043899991222b70fea4 457 SUPERFAMILY SSF55816 279 455 9.68E-31 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 11-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 11-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 Gene3D G3DSA:1.10.300.10 100 199 8.1E-105 T 11-10-2018 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 SMART SM00788 3 422 2.5E-294 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 Pfam PF00709 Adenylosuccinate synthetase 4 420 1.0E-185 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 1.5E-200 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 Gene3D G3DSA:3.40.440.10 5 252 8.1E-105 T 11-10-2018 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 212.837 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 Gene3D G3DSA:3.90.170.10 265 429 2.3E-71 T 11-10-2018 UP12_18935 fe16e3b34da6651e72b761a0a6a20985 429 SUPERFAMILY SSF52540 1 427 1.7E-175 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12045 8295127fa2c4fdd8feb500c5341ead65 139 SUPERFAMILY SSF46785 2 125 9.08E-32 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_12045 8295127fa2c4fdd8feb500c5341ead65 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 124 5.1E-34 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_12045 8295127fa2c4fdd8feb500c5341ead65 139 Pfam PF02082 Transcriptional regulator 1 82 2.4E-26 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_12045 8295127fa2c4fdd8feb500c5341ead65 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 11-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site UP12_12045 8295127fa2c4fdd8feb500c5341ead65 139 Gene3D G3DSA:1.10.10.10 1 139 2.8E-51 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 Gene3D G3DSA:3.40.190.10 160 265 9.3E-58 T 11-10-2018 UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.7E-22 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 Gene3D G3DSA:1.10.10.10 1 90 6.6E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 Pfam PF03466 LysR substrate binding domain 88 289 7.6E-38 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 Gene3D G3DSA:3.40.190.10 91 283 9.3E-58 T 11-10-2018 UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.1E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.1E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.1E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 SUPERFAMILY SSF46785 1 82 5.13E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03040 53e6c1bdb4fdaff1ef8e31c37ea41cd1 297 SUPERFAMILY SSF53850 88 290 6.33E-33 T 11-10-2018 UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 SUPERFAMILY SSF53383 1 357 3.09E-109 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 PIRSF PIRSF000525 1 359 2.3E-146 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 185 204 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 Gene3D G3DSA:3.90.1150.10 256 358 1.0E-39 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 Gene3D G3DSA:3.40.640.10 17 254 2.8E-83 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 358 47.119 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 Pfam PF00266 Aminotransferase class-V 6 347 3.0E-45 T 11-10-2018 IPR000192 Aminotransferase class V domain UP12_05105 311fe2a997631fe81e85d46f54c33c8b 359 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 357 1.7E-152 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 UP12_06300 ebe359c4440df00364747d1087656a13 313 Pfam PF02016 LD-carboxypeptidase 14 293 2.2E-82 T 11-10-2018 IPR003507 Peptidase family S66 UP12_06300 ebe359c4440df00364747d1087656a13 313 SUPERFAMILY SSF52317 3 162 2.06E-52 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_06300 ebe359c4440df00364747d1087656a13 313 SUPERFAMILY SSF141986 142 299 1.29E-41 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_06300 ebe359c4440df00364747d1087656a13 313 Gene3D G3DSA:3.40.50.10740 3 159 3.3E-58 T 11-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal UP12_06300 ebe359c4440df00364747d1087656a13 313 Gene3D G3DSA:3.50.30.60 169 301 3.6E-41 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_06300 ebe359c4440df00364747d1087656a13 313 PIRSF PIRSF028757 3 306 8.1E-89 T 11-10-2018 IPR003507 Peptidase family S66 UP12_14075 3575d308323851f2d943ab7a14ec813e 384 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 8 374 8.8E-108 T 11-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_14075 3575d308323851f2d943ab7a14ec813e 384 Pfam PF01098 Cell cycle protein 11 373 4.8E-98 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_14075 3575d308323851f2d943ab7a14ec813e 384 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 332 356 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_03415 bf890d888e1e4370cd940443a3d10550 229 Pfam PF01144 Coenzyme A transferase 7 215 5.2E-65 T 11-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 UP12_03415 bf890d888e1e4370cd940443a3d10550 229 Gene3D G3DSA:3.40.1080.10 1 218 8.7E-74 T 11-10-2018 UP12_03415 bf890d888e1e4370cd940443a3d10550 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 217 1.1E-63 T 11-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 UP12_03415 bf890d888e1e4370cd940443a3d10550 229 SUPERFAMILY SSF100950 3 220 6.98E-74 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_03415 bf890d888e1e4370cd940443a3d10550 229 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 17 32 - T 11-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 UP12_03415 bf890d888e1e4370cd940443a3d10550 229 SMART SM00882 5 216 2.1E-73 T 11-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 UP12_18255 2cc63b76bf8e54d674b41d06636360c2 286 SUPERFAMILY SSF53697 98 276 3.14E-39 T 11-10-2018 UP12_18255 2cc63b76bf8e54d674b41d06636360c2 286 Gene3D G3DSA:3.40.50.10490 99 284 3.9E-44 T 11-10-2018 UP12_18255 2cc63b76bf8e54d674b41d06636360c2 286 SUPERFAMILY SSF46689 8 84 3.23E-21 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_18255 2cc63b76bf8e54d674b41d06636360c2 286 Gene3D G3DSA:1.10.10.10 5 82 2.0E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18255 2cc63b76bf8e54d674b41d06636360c2 286 Pfam PF01380 SIS domain 132 260 3.1E-19 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_18255 2cc63b76bf8e54d674b41d06636360c2 286 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 82 1.3E-17 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_17770 194fac22331f13607cf069735673e6cf 808 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 233 243 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_17770 194fac22331f13607cf069735673e6cf 808 PRINTS PR00723 Subtilisin serine protease family (S8) signature 229 242 6.7E-22 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_17770 194fac22331f13607cf069735673e6cf 808 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 199 6.7E-22 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_17770 194fac22331f13607cf069735673e6cf 808 PRINTS PR00723 Subtilisin serine protease family (S8) signature 531 547 6.7E-22 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_17770 194fac22331f13607cf069735673e6cf 808 SUPERFAMILY SSF52743 77 599 1.17E-84 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_17770 194fac22331f13607cf069735673e6cf 808 Pfam PF02225 PA domain 383 461 8.5E-14 T 11-10-2018 IPR003137 PA domain UP12_17770 194fac22331f13607cf069735673e6cf 808 Gene3D G3DSA:2.60.40.4070 718 800 6.4E-8 T 11-10-2018 UP12_17770 194fac22331f13607cf069735673e6cf 808 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 532 542 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_17770 194fac22331f13607cf069735673e6cf 808 Pfam PF00082 Subtilase family 180 586 1.4E-77 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_17770 194fac22331f13607cf069735673e6cf 808 Gene3D G3DSA:3.50.30.30 359 477 5.1E-28 T 11-10-2018 UP12_17770 194fac22331f13607cf069735673e6cf 808 Pfam PF05922 Peptidase inhibitor I9 57 142 1.5E-10 T 11-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UP12_17770 194fac22331f13607cf069735673e6cf 808 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 185 196 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UP12_17770 194fac22331f13607cf069735673e6cf 808 SUPERFAMILY SSF52025 379 468 1.54E-13 T 11-10-2018 UP12_17770 194fac22331f13607cf069735673e6cf 808 Pfam PF13860 FlgD Ig-like domain 727 789 2.2E-6 T 11-10-2018 IPR025965 FlgD Ig-like domain UP12_15215 f0c37d6e0abc4739269cbc18a8d00194 144 Pfam PF01934 Protein of unknown function DUF86 10 126 2.8E-20 T 11-10-2018 IPR008201 Protein of unknown function DUF86 UP12_15215 f0c37d6e0abc4739269cbc18a8d00194 144 Gene3D G3DSA:1.20.120.580 1 144 6.6E-57 T 11-10-2018 IPR037038 Bsu32300-like superfamily UP12_06035 41b53cc425e58429eb2b30911c8c03df 168 Pfam PF13302 Acetyltransferase (GNAT) domain 13 154 1.5E-29 T 11-10-2018 IPR000182 GNAT domain UP12_06035 41b53cc425e58429eb2b30911c8c03df 168 Gene3D G3DSA:3.40.630.30 8 166 9.7E-41 T 11-10-2018 UP12_06035 41b53cc425e58429eb2b30911c8c03df 168 SUPERFAMILY SSF55729 9 166 6.05E-39 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_04290 77a440f0b3a88a12515e78e9724bf47b 298 SUPERFAMILY SSF51735 2 262 4.24E-41 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_04290 77a440f0b3a88a12515e78e9724bf47b 298 Pfam PF08338 Domain of unknown function (DUF1731) 250 293 9.0E-15 T 11-10-2018 IPR013549 Domain of unknown function DUF1731 UP12_04290 77a440f0b3a88a12515e78e9724bf47b 298 Gene3D G3DSA:3.40.50.720 2 297 9.5E-73 T 11-10-2018 UP12_04290 77a440f0b3a88a12515e78e9724bf47b 298 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 8.5E-105 T 11-10-2018 IPR010099 Epimerase family protein SDR39U1 UP12_04290 77a440f0b3a88a12515e78e9724bf47b 298 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 1.7E-18 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UP12_03880 456b3e3fb4a4e18d35292de2e9c2b664 543 SUPERFAMILY SSF53187 68 345 8.27E-37 T 11-10-2018 UP12_03880 456b3e3fb4a4e18d35292de2e9c2b664 543 Gene3D G3DSA:3.40.630.10 53 350 3.6E-32 T 11-10-2018 UP12_03880 456b3e3fb4a4e18d35292de2e9c2b664 543 Pfam PF00246 Zinc carboxypeptidase 75 189 8.2E-17 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UP12_03880 456b3e3fb4a4e18d35292de2e9c2b664 543 SMART SM00631 68 325 5.5E-5 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 Gene3D G3DSA:2.30.30.240 96 174 4.8E-22 T 11-10-2018 UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 5 171 23.772 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 Pfam PF01782 RimM N-terminal domain 8 91 3.9E-23 T 11-10-2018 IPR002676 RimM, N-terminal GO:0006364 UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 Gene3D G3DSA:2.40.30.60 5 93 2.4E-20 T 11-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 Pfam PF05239 PRC-barrel domain 98 171 7.4E-13 T 11-10-2018 IPR027275 PRC-barrel domain UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 SUPERFAMILY SSF50346 101 171 1.28E-19 T 11-10-2018 IPR011033 PRC-barrel-like superfamily UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 171 4.7E-51 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 UP12_07800 8f1b881c5b7f15af13d92ea928653fb2 174 SUPERFAMILY SSF50447 4 93 3.88E-21 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:1.10.1200.10 2054 2136 2.1E-16 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:1.10.1200.10 913 1000 1.4E-24 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF53901 9 434 9.87E-86 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 174 190 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SMART SM00825 Beta-ketoacyl synthase 13 438 3.3E-179 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Pfam PF00550 Phosphopantetheine attachment site 927 989 1.2E-15 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Pfam PF00550 Phosphopantetheine attachment site 2068 2128 9.0E-10 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 388 495 2.3E-22 T 11-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 ProSitePatterns PS00012 Phosphopantetheine attachment site. 949 964 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_03550 70a918211e8339acd596cc8705dc7656 2136 TIGRFAM TIGR01686 FkbH: FkbH domain 1642 1958 1.6E-80 T 11-10-2018 IPR010037 FkbH domain UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 12 261 1.4E-69 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.40.47.10 8 438 5.1E-162 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.40.50.1000 1641 1800 1.9E-47 T 11-10-2018 IPR023214 HAD superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF56784 1641 1753 1.2E-6 T 11-10-2018 IPR036412 HAD-like superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF52151 534 828 4.45E-68 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF52777 1005 1193 3.22E-44 T 11-10-2018 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 269 386 2.2E-44 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF55729 1829 1944 9.4E-6 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.40.366.10 535 838 1.8E-148 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.40.630.30 1829 1963 5.8E-5 T 11-10-2018 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF55048 663 723 1.24E-8 T 11-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SMART SM00823 Phosphopantetheine attachment site 925 994 6.6E-4 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Pfam PF00698 Acyl transferase domain 535 824 1.7E-52 T 11-10-2018 IPR014043 Acyl transferase UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.30.559.30 1179 1425 6.1E-131 T 11-10-2018 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.30.559.10 1011 1366 6.1E-131 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Pfam PF00668 Condensation domain 1007 1439 1.2E-111 T 11-10-2018 IPR001242 Condensation domain UP12_03550 70a918211e8339acd596cc8705dc7656 2136 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 1642 1754 1.3E-16 T 11-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.40.50.1110 1435 1638 3.8E-5 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 Gene3D G3DSA:3.30.70.3290 452 883 1.8E-148 T 11-10-2018 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF52777 1183 1431 1.56E-50 T 11-10-2018 UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF47336 2057 2129 5.89E-14 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SUPERFAMILY SSF47336 919 991 1.31E-18 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03550 70a918211e8339acd596cc8705dc7656 2136 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 537 832 6.3E-104 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 SUPERFAMILY SSF52343 94 255 6.55E-30 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 PRINTS PR00409 Phthalate dioxygenase reductase family signature 111 130 7.0E-5 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 PRINTS PR00409 Phthalate dioxygenase reductase family signature 188 196 7.0E-5 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 PRINTS PR00409 Phthalate dioxygenase reductase family signature 52 66 7.0E-5 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 Gene3D G3DSA:2.40.30.10 2 97 3.2E-28 T 11-10-2018 UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 254 6.4E-17 T 11-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 3 256 38.197 T 11-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 PIRSF PIRSF006816 1 257 1.3E-70 T 11-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 SUPERFAMILY SSF63380 3 99 5.55E-21 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 Gene3D G3DSA:2.10.240.10 215 256 1.7E-19 T 11-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 Pfam PF00175 Oxidoreductase NAD-binding domain 112 202 1.9E-4 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 UP12_07560 90acc2bf605bcdd81d38cf5c2f98b75c 258 Gene3D G3DSA:3.40.50.80 102 214 9.4E-25 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain UP12_14805 8c5ceb9cb87dce1a00b4297195c9502c 78 Pfam PF04070 Domain of unknown function (DUF378) 3 61 4.5E-27 T 11-10-2018 IPR007211 Protein of unknown function DUF378 UP12_16220 14e73839be673676fae95a2bf78e6459 295 Gene3D G3DSA:3.40.50.300 1 173 1.3E-6 T 11-10-2018 UP12_16220 14e73839be673676fae95a2bf78e6459 295 Pfam PF03668 P-loop ATPase protein family 9 292 2.1E-136 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 UP12_16220 14e73839be673676fae95a2bf78e6459 295 PIRSF PIRSF005052 9 294 2.2E-110 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 UP12_16220 14e73839be673676fae95a2bf78e6459 295 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 9 291 42.199 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 UP12_16220 14e73839be673676fae95a2bf78e6459 295 SUPERFAMILY SSF52540 11 165 6.79E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18115 7b868a1ee18bca796cb14700c3618497 110 Gene3D G3DSA:1.10.10.10 2 109 2.4E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18115 7b868a1ee18bca796cb14700c3618497 110 SUPERFAMILY SSF46785 5 99 5.12E-30 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18115 7b868a1ee18bca796cb14700c3618497 110 Pfam PF01638 HxlR-like helix-turn-helix 15 99 3.5E-28 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_05900 7539708f03496abd270ab90651a7c048 770 SUPERFAMILY SSF52540 140 755 5.76E-130 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05900 7539708f03496abd270ab90651a7c048 770 Gene3D G3DSA:3.40.50.300 414 751 5.4E-79 T 11-10-2018 UP12_05900 7539708f03496abd270ab90651a7c048 770 Pfam PF13361 UvrD-like helicase C-terminal domain 409 736 7.8E-44 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UP12_05900 7539708f03496abd270ab90651a7c048 770 Pfam PF00580 UvrD/REP helicase N-terminal domain 143 267 3.6E-26 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UP12_05900 7539708f03496abd270ab90651a7c048 770 Pfam PF00580 UvrD/REP helicase N-terminal domain 294 403 3.7E-37 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UP12_05900 7539708f03496abd270ab90651a7c048 770 Gene3D G3DSA:3.40.50.300 144 404 9.8E-81 T 11-10-2018 UP12_05900 7539708f03496abd270ab90651a7c048 770 Gene3D G3DSA:1.10.486.10 515 663 5.4E-79 T 11-10-2018 UP12_05900 7539708f03496abd270ab90651a7c048 770 Gene3D G3DSA:1.10.10.160 247 319 9.8E-81 T 11-10-2018 IPR013986 DExx box DNA helicase domain superfamily UP12_14810 eb53d9a298a38286a86c53caad9cde20 130 Gene3D G3DSA:2.40.50.140 2 88 8.4E-33 T 11-10-2018 UP12_14810 eb53d9a298a38286a86c53caad9cde20 130 SMART SM00316 6 77 7.3E-26 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_14810 eb53d9a298a38286a86c53caad9cde20 130 SUPERFAMILY SSF50249 5 87 7.86E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_14810 eb53d9a298a38286a86c53caad9cde20 130 Pfam PF00575 S1 RNA binding domain 4 77 6.9E-21 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_19245 7cd1f7cd4b6162de635f5a793c70f7c9 282 ProDom PD304634 PLASMID TRANSMEMBRANE PXO2-23/BXB0022/GBAA_PXO2_0022 MEMBRANE 12 269 4.0E-29 T 11-10-2018 IPR020397 Uncharacterised protein family, plasmid pXO2-23 UP12_19245 7cd1f7cd4b6162de635f5a793c70f7c9 282 SUPERFAMILY SSF90123 30 100 4.32E-5 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_01235 8d7a6e9585a009a02b519922e72a4aed 256 SUPERFAMILY SSF109998 67 229 5.89E-30 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily UP12_01235 8d7a6e9585a009a02b519922e72a4aed 256 Pfam PF13624 SurA N-terminal domain 67 182 5.7E-19 T 11-10-2018 UP12_01235 8d7a6e9585a009a02b519922e72a4aed 256 Gene3D G3DSA:1.10.4030.30 59 255 3.6E-30 T 11-10-2018 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 Gene3D G3DSA:1.25.40.10 32 103 1.4E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 Gene3D G3DSA:1.25.40.10 310 422 2.2E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 Pfam PF13432 Tetratricopeptide repeat 177 237 0.0013 T 11-10-2018 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SUPERFAMILY SSF48452 26 271 1.37E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 Pfam PF14559 Tetratricopeptide repeat 47 110 1.7E-5 T 11-10-2018 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SUPERFAMILY SSF48452 203 408 1.14E-25 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 Gene3D G3DSA:1.25.40.10 104 202 1.8E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 Gene3D G3DSA:1.25.40.10 203 309 1.2E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SMART SM00028 272 305 180.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SMART SM00028 374 407 120.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SMART SM00028 171 204 4.3 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SMART SM00028 101 134 84.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SMART SM00028 135 168 66.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 SMART SM00028 238 271 23.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10135 1d1458bde86e72133daa318cf2592a9e 423 Pfam PF13429 Tetratricopeptide repeat 275 402 2.2E-6 T 11-10-2018 UP12_06565 e2c953d7630d3e50bb751bcdae5196b5 396 Gene3D G3DSA:3.90.1150.10 26 383 8.3E-119 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_06565 e2c953d7630d3e50bb751bcdae5196b5 396 SUPERFAMILY SSF53383 4 385 9.49E-106 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_06565 e2c953d7630d3e50bb751bcdae5196b5 396 Pfam PF00155 Aminotransferase class I and II 33 383 4.6E-69 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_06565 e2c953d7630d3e50bb751bcdae5196b5 396 Gene3D G3DSA:3.40.640.10 44 285 8.3E-119 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_03355 5b36fc5f3a5d3bdf6ec17881ef3518db 84 Gene3D G3DSA:3.30.1280.10 1 84 1.2E-37 T 11-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03355 5b36fc5f3a5d3bdf6ec17881ef3518db 84 SUPERFAMILY SSF82697 1 80 5.23E-30 T 11-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03355 5b36fc5f3a5d3bdf6ec17881ef3518db 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 1.4E-32 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03355 5b36fc5f3a5d3bdf6ec17881ef3518db 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 80 4.0E-33 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03355 5b36fc5f3a5d3bdf6ec17881ef3518db 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 2.0E-36 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_03355 5b36fc5f3a5d3bdf6ec17881ef3518db 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 21.792 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 UP12_02540 d3c5e42bac60653eec49f25d3dbed6b2 93 SUPERFAMILY SSF47598 7 55 1.0E-6 T 11-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 UP12_02540 d3c5e42bac60653eec49f25d3dbed6b2 93 Gene3D G3DSA:1.10.1220.10 1 93 5.9E-35 T 11-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 UP12_07540 0849e8356b398b90c72e7232feb04561 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 3.4E-40 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 Gene3D G3DSA:3.40.50.1370 127 268 5.0E-107 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 287 3.6E-100 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 Gene3D G3DSA:3.40.50.1370 6 285 5.0E-107 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 270 284 4.3E-35 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 4.3E-35 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 246 251 4.3E-35 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 4.3E-35 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 4.3E-35 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 4.3E-35 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 291 38.344 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 1.7E-24 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 254 277 1.7E-24 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 242 251 1.7E-24 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 1.7E-24 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 146 285 2.6E-23 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 UP12_07540 0849e8356b398b90c72e7232feb04561 307 SUPERFAMILY SSF53671 1 290 1.27E-90 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 UP12_16215 3d24f765bd3ca0e0d1bf8391d4721ad6 319 Gene3D G3DSA:3.40.50.12300 3 319 8.6E-132 T 11-10-2018 IPR038136 Gluconeogenesis factor superfamily UP12_16215 3d24f765bd3ca0e0d1bf8391d4721ad6 319 Pfam PF01933 Uncharacterised protein family UPF0052 7 290 2.2E-109 T 11-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 UP12_16215 3d24f765bd3ca0e0d1bf8391d4721ad6 319 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 7 315 2.6E-129 T 11-10-2018 IPR010119 Gluconeogenesis factor UP12_16215 3d24f765bd3ca0e0d1bf8391d4721ad6 319 Hamap MF_00973 Gluconeogenesis factor. 3 317 36.554 T 11-10-2018 IPR010119 Gluconeogenesis factor UP12_16215 3d24f765bd3ca0e0d1bf8391d4721ad6 319 SUPERFAMILY SSF142338 5 312 4.58E-110 T 11-10-2018 UP12_08415 66e190b35a8f8e06bf92504df4f9c8f3 105 SUPERFAMILY SSF103481 6 104 1.28E-19 T 11-10-2018 UP12_08415 66e190b35a8f8e06bf92504df4f9c8f3 105 Pfam PF00893 Small Multidrug Resistance protein 4 95 2.2E-29 T 11-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UP12_08415 66e190b35a8f8e06bf92504df4f9c8f3 105 Gene3D G3DSA:1.10.3730.20 3 105 6.2E-33 T 11-10-2018 UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 3.8E-36 T 11-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 SUPERFAMILY SSF55608 120 221 9.07E-19 T 11-10-2018 IPR027434 Homing endonuclease UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 3.1E-132 T 11-10-2018 IPR033981 Sporulation regulator WhiA-like UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 Gene3D G3DSA:1.10.10.10 215 309 2.8E-37 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 Pfam PF14527 WhiA LAGLIDADG-like domain 125 217 2.3E-36 T 11-10-2018 IPR039518 WhiA, LAGLIDADG-like domain UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 Pfam PF02650 WhiA C-terminal HTH domain 220 304 2.7E-35 T 11-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 35.74 T 11-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 UP12_16210 ce1be8ee109039a7678ac3a7798e32bb 316 Gene3D G3DSA:3.10.28.10 1 214 2.9E-66 T 11-10-2018 IPR027434 Homing endonuclease UP12_10475 ecab08f9265972db1579c9b388a48f10 216 Gene3D G3DSA:2.40.30.20 102 204 1.1E-31 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_10475 ecab08f9265972db1579c9b388a48f10 216 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 7.6E-81 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_10475 ecab08f9265972db1579c9b388a48f10 216 Pfam PF00677 Lumazine binding domain 3 87 5.8E-24 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_10475 ecab08f9265972db1579c9b388a48f10 216 Pfam PF00677 Lumazine binding domain 100 184 3.9E-21 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_10475 ecab08f9265972db1579c9b388a48f10 216 SUPERFAMILY SSF63380 93 195 1.7E-30 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UP12_10475 ecab08f9265972db1579c9b388a48f10 216 SUPERFAMILY SSF63380 1 88 1.11E-24 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel UP12_10475 ecab08f9265972db1579c9b388a48f10 216 Gene3D G3DSA:2.40.30.20 1 89 6.5E-33 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_10475 ecab08f9265972db1579c9b388a48f10 216 PIRSF PIRSF000498 1 211 3.3E-78 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_14085 70f2f0c49fcf101502e55f1a78d8ab37 515 Gene3D G3DSA:3.30.479.30 78 194 7.6E-39 T 11-10-2018 UP12_14085 70f2f0c49fcf101502e55f1a78d8ab37 515 Pfam PF01145 SPFH domain / Band 7 family 31 220 8.6E-26 T 11-10-2018 IPR001107 Band 7 domain UP12_14085 70f2f0c49fcf101502e55f1a78d8ab37 515 SUPERFAMILY SSF117892 69 211 3.27E-35 T 11-10-2018 IPR036013 Band 7/SPFH domain superfamily UP12_14085 70f2f0c49fcf101502e55f1a78d8ab37 515 Pfam PF15975 Flotillin 369 464 1.5E-15 T 11-10-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 UP12_14085 70f2f0c49fcf101502e55f1a78d8ab37 515 SMART SM00244 120 302 1.1E-12 T 11-10-2018 IPR001107 Band 7 domain UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 553 672 3.7E-47 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 552 674 1.9E-50 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 516 1.6E-247 T 11-10-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 64 365 3.1E-95 T 11-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 SUPERFAMILY SSF55604 443 513 4.58E-20 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 454 471 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 Gene3D G3DSA:3.30.1360.60 439 517 1.4E-28 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 413 500 3.6E-28 T 11-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 Pfam PF02378 Phosphotransferase system, EIIC 14 354 4.3E-98 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 Gene3D G3DSA:2.70.70.10 538 699 1.4E-63 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 SUPERFAMILY SSF51261 545 696 2.44E-55 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 Pfam PF00367 phosphotransferase system, EIIB 444 476 8.7E-14 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_06700 f7023d0f6586ee804f3350ba36f2e715 699 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 614 626 - T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_09585 4ede7a00b28d4863241edce56609b82f 157 Gene3D G3DSA:2.60.40.790 62 146 1.1E-10 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_09585 4ede7a00b28d4863241edce56609b82f 157 SUPERFAMILY SSF49764 69 155 1.31E-12 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 SUPERFAMILY SSF51569 1 285 3.52E-105 T 11-10-2018 UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 PIRSF PIRSF001359 1 285 2.9E-127 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 7.2E-134 T 11-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 Gene3D G3DSA:3.20.20.70 1 285 2.8E-114 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 8.6E-105 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 2.8E-118 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_17325 2513f93050b2f3726c16a2fbd29122d0 285 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 SUPERFAMILY SSF51905 2 345 2.02E-59 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 Gene3D G3DSA:3.50.50.60 5 341 1.1E-114 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 Gene3D G3DSA:3.30.390.30 354 474 3.8E-46 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PIRSF PIRSF000350 1 472 1.4E-86 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 SUPERFAMILY SSF55424 351 473 2.23E-39 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 335 6.7E-65 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 287 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 315 322 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 416 431 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 351 372 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 5.0E-68 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 355 463 2.9E-37 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 Gene3D G3DSA:3.50.50.60 159 282 1.1E-114 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.8E-36 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 288 1.8E-36 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.8E-36 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.8E-36 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 1.8E-36 T 11-10-2018 UP12_10895 ef46942db78dec17f73260711ad6ac7f 474 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 474 4.2E-181 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UP12_04085 489cf28cdb232cb18947d0cbd9c81d88 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 7.6E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_04085 489cf28cdb232cb18947d0cbd9c81d88 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 7.6E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_04085 489cf28cdb232cb18947d0cbd9c81d88 188 SUPERFAMILY SSF48498 76 188 2.16E-15 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_04085 489cf28cdb232cb18947d0cbd9c81d88 188 Gene3D G3DSA:1.10.357.10 1 188 2.3E-38 T 11-10-2018 UP12_04085 489cf28cdb232cb18947d0cbd9c81d88 188 SUPERFAMILY SSF46689 3 69 4.62E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_04085 489cf28cdb232cb18947d0cbd9c81d88 188 Pfam PF16925 Bacterial transcriptional repressor C-terminal 77 186 6.2E-8 T 11-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UP12_04085 489cf28cdb232cb18947d0cbd9c81d88 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 50 2.0E-13 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_00895 4ad829373d6b42f329144bea7d04e0d4 145 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 142 5.1E-66 T 11-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00895 4ad829373d6b42f329144bea7d04e0d4 145 Pfam PF00572 Ribosomal protein L13 15 139 1.2E-57 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UP12_00895 4ad829373d6b42f329144bea7d04e0d4 145 PIRSF PIRSF002181 1 143 1.4E-50 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UP12_00895 4ad829373d6b42f329144bea7d04e0d4 145 ProSitePatterns PS00783 Ribosomal protein L13 signature. 106 128 - T 11-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 UP12_00895 4ad829373d6b42f329144bea7d04e0d4 145 Gene3D G3DSA:3.90.1180.10 1 143 1.0E-61 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00895 4ad829373d6b42f329144bea7d04e0d4 145 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 144 28.599 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 UP12_00895 4ad829373d6b42f329144bea7d04e0d4 145 SUPERFAMILY SSF52161 6 143 5.1E-60 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 SUPERFAMILY SSF63520 170 273 8.24E-27 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 SMART SM01061 1 59 1.9E-28 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 Pfam PF00874 PRD domain 180 272 3.7E-18 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 Pfam PF00874 PRD domain 76 163 8.2E-26 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 Pfam PF03123 CAT RNA binding domain 2 56 1.5E-23 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 SUPERFAMILY SSF50151 2 54 2.62E-17 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 ProSitePatterns PS00654 PRD domain signature. 98 110 - T 11-10-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 Gene3D G3DSA:2.30.24.10 1 55 1.1E-23 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 Gene3D G3DSA:1.10.1790.10 168 277 4.1E-40 T 11-10-2018 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 Gene3D G3DSA:1.10.1790.10 64 167 4.9E-40 T 11-10-2018 UP12_18290 eb26a8858713366370bc4e7f4d7841c0 277 SUPERFAMILY SSF63520 57 166 2.88E-33 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 223 249 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 PRINTS PR00046 Major sigma-70 factor signature 206 218 2.3E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 PRINTS PR00046 Major sigma-70 factor signature 223 238 2.3E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 PRINTS PR00046 Major sigma-70 factor signature 58 71 2.3E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 PRINTS PR00046 Major sigma-70 factor signature 238 249 2.3E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 Gene3D G3DSA:1.20.140.160 106 256 2.0E-29 T 11-10-2018 UP12_02580 f871804498ec73d6de218d856189213c 262 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 28 253 2.2E-87 T 11-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_02580 f871804498ec73d6de218d856189213c 262 Gene3D G3DSA:1.20.120.1810 1 102 2.4E-14 T 11-10-2018 UP12_02580 f871804498ec73d6de218d856189213c 262 Pfam PF04542 Sigma-70 region 2 34 103 6.8E-13 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 SUPERFAMILY SSF88659 107 180 6.1E-13 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_02580 f871804498ec73d6de218d856189213c 262 SUPERFAMILY SSF88946 4 103 2.35E-25 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 Pfam PF04539 Sigma-70 region 3 113 187 4.8E-16 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 TIGRFAM TIGR02941 Sigma_B: RNA polymerase sigma-B factor 1 253 6.7E-120 T 11-10-2018 IPR014288 RNA polymerase sigma-B factor GO:0016987 UP12_02580 f871804498ec73d6de218d856189213c 262 SUPERFAMILY SSF88659 172 255 3.74E-17 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_02580 f871804498ec73d6de218d856189213c 262 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 253 3.7E-33 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_02580 f871804498ec73d6de218d856189213c 262 Pfam PF04545 Sigma-70, region 4 202 251 1.9E-16 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_12715 ea444679d3f91baf0eab79d8e5fd6db1 127 Gene3D G3DSA:1.20.140.160 2 125 3.5E-6 T 11-10-2018 UP12_12715 ea444679d3f91baf0eab79d8e5fd6db1 127 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 9 126 3.2E-21 T 11-10-2018 IPR006524 Transcription activator, ArpU family UP12_07520 37a7d742670cfa21cdffa2dbf4c20889 155 TIGRFAM TIGR00077 lspA: signal peptidase II 2 151 4.1E-51 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UP12_07520 37a7d742670cfa21cdffa2dbf4c20889 155 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 150 16.974 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UP12_07520 37a7d742670cfa21cdffa2dbf4c20889 155 Pfam PF01252 Signal peptidase (SPase) II 6 144 3.3E-40 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UP12_07520 37a7d742670cfa21cdffa2dbf4c20889 155 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UP12_07520 37a7d742670cfa21cdffa2dbf4c20889 155 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 2.2E-18 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UP12_07520 37a7d742670cfa21cdffa2dbf4c20889 155 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 2.2E-18 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UP12_07520 37a7d742670cfa21cdffa2dbf4c20889 155 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 2.2E-18 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 UP12_04115 417eb119a8719bca609cd4fb997c1d25 276 SUPERFAMILY SSF48371 82 273 1.92E-35 T 11-10-2018 IPR016024 Armadillo-type fold UP12_04115 417eb119a8719bca609cd4fb997c1d25 276 Gene3D G3DSA:1.25.40.290 154 273 1.9E-33 T 11-10-2018 UP12_04115 417eb119a8719bca609cd4fb997c1d25 276 Pfam PF08713 DNA alkylation repair enzyme 151 249 5.1E-8 T 11-10-2018 IPR014825 DNA alkylation repair enzyme UP12_01810 d8da6ec7b3c263fb5a1cd38edcaedd08 477 Pfam PF00171 Aldehyde dehydrogenase family 14 471 1.6E-148 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_01810 d8da6ec7b3c263fb5a1cd38edcaedd08 477 Gene3D G3DSA:3.40.309.10 254 441 3.9E-145 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_01810 d8da6ec7b3c263fb5a1cd38edcaedd08 477 Gene3D G3DSA:3.40.605.10 10 469 3.9E-145 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_01810 d8da6ec7b3c263fb5a1cd38edcaedd08 477 SUPERFAMILY SSF53720 8 473 1.83E-139 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 SMART SM00382 56 227 3.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_08295 a95182fb8e66153392566b4026d9ab46 346 SUPERFAMILY SSF54752 267 326 1.83E-21 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal UP12_08295 a95182fb8e66153392566b4026d9ab46 346 ProSitePatterns PS00321 recA signature. 212 220 - T 11-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 Hamap MF_00268 Protein RecA [recA]. 4 328 53.139 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 323 1.5E-176 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 SUPERFAMILY SSF52540 3 266 7.36E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08295 a95182fb8e66153392566b4026d9ab46 346 Gene3D G3DSA:3.30.250.10 267 343 3.6E-28 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal UP12_08295 a95182fb8e66153392566b4026d9ab46 346 Pfam PF00154 recA bacterial DNA recombination protein 7 267 3.5E-147 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 Gene3D G3DSA:3.40.50.300 25 266 1.1E-81 T 11-10-2018 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 PRINTS PR00142 RecA protein signature 296 313 3.8E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 PRINTS PR00142 RecA protein signature 92 121 3.8E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 PRINTS PR00142 RecA protein signature 126 155 3.8E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 PRINTS PR00142 RecA protein signature 209 237 3.8E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 PRINTS PR00142 RecA protein signature 242 271 3.8E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_08295 a95182fb8e66153392566b4026d9ab46 346 PRINTS PR00142 RecA protein signature 164 193 3.8E-85 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 UP12_07610 87bed0ae186a572486150f07af53ae13 167 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 147 8.1E-30 T 11-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 UP12_07610 87bed0ae186a572486150f07af53ae13 167 Gene3D G3DSA:3.40.50.720 1 127 2.4E-37 T 11-10-2018 UP12_07610 87bed0ae186a572486150f07af53ae13 167 SUPERFAMILY SSF51735 1 100 3.94E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_07610 87bed0ae186a572486150f07af53ae13 167 Pfam PF13241 Putative NAD(P)-binding 6 111 1.6E-25 T 11-10-2018 UP12_07610 87bed0ae186a572486150f07af53ae13 167 SUPERFAMILY SSF75615 105 161 9.68E-9 T 11-10-2018 UP12_05690 d6736e31ddc5f2b0c0421d87466627e5 545 SUPERFAMILY SSF53850 35 537 6.67E-138 T 11-10-2018 UP12_05690 d6736e31ddc5f2b0c0421d87466627e5 545 PIRSF PIRSF002741 1 544 1.2E-146 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UP12_05690 d6736e31ddc5f2b0c0421d87466627e5 545 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 466 3.7E-88 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain UP12_05690 d6736e31ddc5f2b0c0421d87466627e5 545 Gene3D G3DSA:3.40.190.10 52 530 6.6E-174 T 11-10-2018 UP12_05690 d6736e31ddc5f2b0c0421d87466627e5 545 Gene3D G3DSA:3.10.105.10 299 517 6.6E-174 T 11-10-2018 UP12_05690 d6736e31ddc5f2b0c0421d87466627e5 545 Gene3D G3DSA:3.90.76.10 72 193 6.6E-174 T 11-10-2018 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 SMART SM00729 60 268 1.2E-30 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 Pfam PF04055 Radical SAM superfamily 69 224 9.9E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 SUPERFAMILY SSF102114 20 327 3.92E-69 T 11-10-2018 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 TIGRFAM TIGR00433 bioB: biotin synthase 33 324 1.0E-118 T 11-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 SMART SM00876 236 326 3.5E-31 T 11-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 236 324 2.1E-14 T 11-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 PIRSF PIRSF001619 3 331 5.8E-122 T 11-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 Hamap MF_01694 Biotin synthase [bioB]. 20 327 39.556 T 11-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 UP12_14685 13f587703f6fb41e6e192c5519cafd8c 331 Gene3D G3DSA:3.20.20.70 23 328 7.7E-107 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 SUPERFAMILY SSF63520 291 398 3.27E-25 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 SUPERFAMILY SSF55804 499 635 2.75E-27 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 SUPERFAMILY SSF46785 95 158 8.98E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Pfam PF05043 Mga helix-turn-helix domain 73 171 4.1E-14 T 11-10-2018 IPR007737 Mga helix-turn-helix domain UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Gene3D G3DSA:3.40.50.2300 405 490 5.8E-10 T 11-10-2018 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Gene3D G3DSA:1.10.1790.10 183 283 2.9E-14 T 11-10-2018 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Pfam PF08279 HTH domain 5 62 6.7E-11 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Gene3D G3DSA:3.40.930.10 497 637 3.9E-23 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Gene3D G3DSA:1.10.1790.10 297 397 7.7E-24 T 11-10-2018 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 SUPERFAMILY SSF63520 183 280 3.14E-17 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 SUPERFAMILY SSF46785 4 64 9.07E-7 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Gene3D G3DSA:1.10.10.10 80 158 1.7E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Gene3D G3DSA:1.10.10.10 1 65 2.4E-10 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 501 636 7.8E-27 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 408 481 3.8E-6 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 SUPERFAMILY SSF52794 406 481 4.13E-6 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Pfam PF00874 PRD domain 199 279 1.5E-12 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_18170 bf446ca7fe0fd991ca94e3ef436ae3eb 652 Pfam PF00874 PRD domain 315 395 5.8E-22 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_12120 7e47a908d07976e01f078b5794695660 220 Pfam PF04239 Protein of unknown function (DUF421) 88 193 2.1E-37 T 11-10-2018 IPR007353 Protein of unknown function DUF421 UP12_12120 7e47a908d07976e01f078b5794695660 220 Gene3D G3DSA:3.30.240.20 81 154 3.1E-24 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily UP12_12120 7e47a908d07976e01f078b5794695660 220 Gene3D G3DSA:3.30.240.20 160 216 3.2E-15 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily UP12_15260 9ef692124b7667e857335d9d7f5dc89e 283 Pfam PF01904 Protein of unknown function DUF72 16 265 2.6E-59 T 11-10-2018 IPR002763 Protein of unknown function DUF72 UP12_15260 9ef692124b7667e857335d9d7f5dc89e 283 SUPERFAMILY SSF117396 1 268 3.79E-85 T 11-10-2018 IPR036520 UPF0759 superfamily UP12_15260 9ef692124b7667e857335d9d7f5dc89e 283 Gene3D G3DSA:3.20.20.410 1 282 3.5E-95 T 11-10-2018 IPR036520 UPF0759 superfamily UP12_10560 769d51ddd1e6ab2abed61f0a68d255dc 117 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 6 110 4.4E-46 T 11-10-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 UP12_10560 769d51ddd1e6ab2abed61f0a68d255dc 117 Pfam PF01740 STAS domain 7 109 1.0E-24 T 11-10-2018 IPR002645 STAS domain UP12_10560 769d51ddd1e6ab2abed61f0a68d255dc 117 SUPERFAMILY SSF52091 3 113 5.89E-31 T 11-10-2018 IPR036513 STAS domain superfamily UP12_10560 769d51ddd1e6ab2abed61f0a68d255dc 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 106 1.4E-37 T 11-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 UP12_10560 769d51ddd1e6ab2abed61f0a68d255dc 117 Gene3D G3DSA:3.30.750.24 2 117 7.7E-34 T 11-10-2018 IPR036513 STAS domain superfamily UP12_11075 a612ecd1bdeea89ace48a3f5a885f38a 318 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 57 295 1.0E-113 T 11-10-2018 IPR010787 Protein of unknown function DUF1385 UP12_11075 a612ecd1bdeea89ace48a3f5a885f38a 318 Pfam PF07136 Protein of unknown function (DUF1385) 57 300 4.9E-81 T 11-10-2018 IPR010787 Protein of unknown function DUF1385 UP12_03865 c70078459fb029e285db5bbd93938d01 232 Pfam PF00072 Response regulator receiver domain 4 115 1.2E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_03865 c70078459fb029e285db5bbd93938d01 232 PIRSF PIRSF006171 1 229 1.5E-79 T 11-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 UP12_03865 c70078459fb029e285db5bbd93938d01 232 Pfam PF08279 HTH domain 166 224 7.9E-6 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_03865 c70078459fb029e285db5bbd93938d01 232 SMART SM00448 2 115 1.2E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_03865 c70078459fb029e285db5bbd93938d01 232 Gene3D G3DSA:3.40.50.12740 2 215 3.5E-27 T 11-10-2018 UP12_03865 c70078459fb029e285db5bbd93938d01 232 SUPERFAMILY SSF52172 2 133 1.2E-29 T 11-10-2018 IPR011006 CheY-like superfamily UP12_10310 c15604ecc6502376eb93d8d8136fa4da 303 Gene3D G3DSA:2.40.10.420 268 303 4.2E-20 T 11-10-2018 UP12_10310 c15604ecc6502376eb93d8d8136fa4da 303 SUPERFAMILY SSF47090 33 101 5.49E-19 T 11-10-2018 IPR036365 PGBD-like superfamily UP12_10310 c15604ecc6502376eb93d8d8136fa4da 303 Gene3D G3DSA:1.10.101.10 27 109 2.7E-20 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UP12_10310 c15604ecc6502376eb93d8d8136fa4da 303 Gene3D G3DSA:1.10.10.2520 188 267 4.7E-31 T 11-10-2018 UP12_10310 c15604ecc6502376eb93d8d8136fa4da 303 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 31 302 1.8E-92 T 11-10-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 UP12_10310 c15604ecc6502376eb93d8d8136fa4da 303 Pfam PF07486 Cell Wall Hydrolase 204 302 2.0E-25 T 11-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 UP12_10310 c15604ecc6502376eb93d8d8136fa4da 303 Pfam PF01471 Putative peptidoglycan binding domain 42 99 8.1E-15 T 11-10-2018 IPR002477 Peptidoglycan binding-like UP12_02935 8212dadf652789131d4a85ceeb5c20f3 150 Gene3D G3DSA:1.10.10.10 13 149 4.5E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02935 8212dadf652789131d4a85ceeb5c20f3 150 SMART SM00347 31 132 2.6E-6 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_02935 8212dadf652789131d4a85ceeb5c20f3 150 SUPERFAMILY SSF46785 20 147 4.65E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02935 8212dadf652789131d4a85ceeb5c20f3 150 Pfam PF12802 MarR family 47 96 2.0E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03900 190a5026b3dcdbcc783cce948fe820cc 90 Pfam PF00708 Acylphosphatase 4 88 1.1E-26 T 11-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UP12_03900 190a5026b3dcdbcc783cce948fe820cc 90 Gene3D G3DSA:3.30.70.100 1 90 2.4E-29 T 11-10-2018 UP12_03900 190a5026b3dcdbcc783cce948fe820cc 90 SUPERFAMILY SSF54975 2 89 2.4E-26 T 11-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UP12_03900 190a5026b3dcdbcc783cce948fe820cc 90 PRINTS PR00112 Acylphosphatase signature 3 18 2.7E-6 T 11-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UP12_03900 190a5026b3dcdbcc783cce948fe820cc 90 PRINTS PR00112 Acylphosphatase signature 24 49 2.7E-6 T 11-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UP12_03900 190a5026b3dcdbcc783cce948fe820cc 90 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 11-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UP12_03900 190a5026b3dcdbcc783cce948fe820cc 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 11-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Gene3D G3DSA:3.40.50.300 4 200 1.1E-66 T 11-10-2018 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 141 1.5E-22 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 SUPERFAMILY SSF50447 153 301 8.25E-33 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Gene3D G3DSA:2.40.50.250 485 601 3.7E-129 T 11-10-2018 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Pfam PF00009 Elongation factor Tu GTP binding domain 6 197 4.6E-57 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Gene3D G3DSA:2.40.30.10 201 301 2.5E-34 T 11-10-2018 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Pfam PF03144 Elongation factor Tu domain 2 221 291 1.7E-12 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 7 601 7.1E-291 T 11-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Gene3D G3DSA:3.30.70.240 391 484 3.7E-129 T 11-10-2018 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Pfam PF14492 Elongation Factor G, domain II 330 382 1.7E-6 T 11-10-2018 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 SMART SM00838 397 485 2.2E-4 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 SUPERFAMILY SSF52540 3 209 1.7E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 PRINTS PR00315 GTP-binding elongation factor signature 89 100 2.6E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.6E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 PRINTS PR00315 GTP-binding elongation factor signature 53 61 2.6E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 PRINTS PR00315 GTP-binding elongation factor signature 125 134 2.6E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 PRINTS PR00315 GTP-binding elongation factor signature 73 83 2.6E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Pfam PF00679 Elongation factor G C-terminus 399 479 1.7E-24 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 SUPERFAMILY SSF54980 304 389 1.22E-15 T 11-10-2018 IPR035647 EF-G domain III/V-like UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 Gene3D G3DSA:3.30.70.870 308 592 3.7E-129 T 11-10-2018 UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 46 61 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site UP12_07145 aeb14b479668c4be9f176510a39eab7f 612 SUPERFAMILY SSF54980 400 515 4.08E-29 T 11-10-2018 IPR035647 EF-G domain III/V-like UP12_11680 c6a0270c74d1121a93fd3f635828fe04 247 SUPERFAMILY SSF52266 30 239 1.83E-36 T 11-10-2018 UP12_11680 c6a0270c74d1121a93fd3f635828fe04 247 Gene3D G3DSA:3.40.50.1110 20 241 1.1E-40 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_11680 c6a0270c74d1121a93fd3f635828fe04 247 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 32 233 1.6E-23 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain UP12_02465 0dce7ca4d7b5f7bec3c702982118dab3 308 Pfam PF00005 ABC transporter 21 162 1.2E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_02465 0dce7ca4d7b5f7bec3c702982118dab3 308 Gene3D G3DSA:3.40.50.300 2 248 7.5E-60 T 11-10-2018 UP12_02465 0dce7ca4d7b5f7bec3c702982118dab3 308 SUPERFAMILY SSF52540 4 224 2.61E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02465 0dce7ca4d7b5f7bec3c702982118dab3 308 SMART SM00382 30 210 3.4E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_02465 0dce7ca4d7b5f7bec3c702982118dab3 308 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18110 58aedc24b23dbcc8e406a2a9d5f4239f 152 SUPERFAMILY SSF158911 17 150 7.06E-39 T 11-10-2018 IPR037250 NEAT domain superfamily UP12_18110 58aedc24b23dbcc8e406a2a9d5f4239f 152 Pfam PF05031 Iron Transport-associated domain 33 147 4.7E-33 T 11-10-2018 IPR006635 NEAT domain UP12_18110 58aedc24b23dbcc8e406a2a9d5f4239f 152 Gene3D G3DSA:2.60.40.1850 25 151 5.1E-41 T 11-10-2018 UP12_18110 58aedc24b23dbcc8e406a2a9d5f4239f 152 SMART SM00725 33 152 2.6E-34 T 11-10-2018 IPR006635 NEAT domain UP12_04040 3ca8b75a0c936026e83f0a60cc750c39 278 SUPERFAMILY SSF50182 101 164 6.87E-11 T 11-10-2018 IPR010920 LSM domain superfamily UP12_04040 3ca8b75a0c936026e83f0a60cc750c39 278 Pfam PF00924 Mechanosensitive ion channel 59 266 6.8E-35 T 11-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 UP12_04040 3ca8b75a0c936026e83f0a60cc750c39 278 Gene3D G3DSA:3.30.70.100 168 265 5.3E-6 T 11-10-2018 UP12_04040 3ca8b75a0c936026e83f0a60cc750c39 278 Gene3D G3DSA:2.30.30.60 116 165 2.5E-17 T 11-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily UP12_04040 3ca8b75a0c936026e83f0a60cc750c39 278 SUPERFAMILY SSF82861 14 99 1.15E-10 T 11-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 UP12_12475 2661afcfa9ffb8e541e6f465162444f1 523 Pfam PF14449 Pre-toxin TG 243 308 1.6E-19 T 11-10-2018 IPR027797 Pre-toxin TG domain UP12_12475 2661afcfa9ffb8e541e6f465162444f1 523 Pfam PF04740 LXG domain of WXG superfamily 2 187 1.8E-39 T 11-10-2018 IPR006829 LXG domain UP12_12475 2661afcfa9ffb8e541e6f465162444f1 523 Pfam PF15657 HNH/Endo VII superfamily nuclease toxins 450 517 1.2E-19 T 11-10-2018 IPR028048 HNH/Endo VII superfamily nuclease toxins UP12_01625 51bd04d4d1f0b6135828dbf57aefd111 330 SUPERFAMILY SSF51679 4 328 8.24E-70 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_01625 51bd04d4d1f0b6135828dbf57aefd111 330 Gene3D G3DSA:3.20.20.30 2 330 5.7E-94 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_01625 51bd04d4d1f0b6135828dbf57aefd111 330 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 4 328 2.0E-116 T 11-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 UP12_01625 51bd04d4d1f0b6135828dbf57aefd111 330 Pfam PF00296 Luciferase-like monooxygenase 12 297 4.6E-34 T 11-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UP12_06910 3df90081eb0dcb213f6e6b7d25427637 193 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 190 22.327 T 11-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 UP12_06910 3df90081eb0dcb213f6e6b7d25427637 193 Gene3D G3DSA:3.90.550.10 5 191 1.3E-43 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_06910 3df90081eb0dcb213f6e6b7d25427637 193 Pfam PF12804 MobA-like NTP transferase domain 6 161 4.2E-30 T 11-10-2018 IPR025877 MobA-like NTP transferase UP12_06910 3df90081eb0dcb213f6e6b7d25427637 193 SUPERFAMILY SSF53448 2 187 1.34E-27 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 42.399 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 PRINTS PR00298 60kDa chaperonin signature 82 109 2.0E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 PRINTS PR00298 60kDa chaperonin signature 26 52 2.0E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 PRINTS PR00298 60kDa chaperonin signature 266 289 2.0E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 PRINTS PR00298 60kDa chaperonin signature 396 417 2.0E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 PRINTS PR00298 60kDa chaperonin signature 348 373 2.0E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 Gene3D G3DSA:3.50.7.10 190 370 1.7E-235 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 SUPERFAMILY SSF48592 5 518 5.33E-80 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 Gene3D G3DSA:3.30.260.10 135 408 1.7E-235 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 SUPERFAMILY SSF52029 183 374 6.88E-85 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 Gene3D G3DSA:1.10.560.10 7 518 1.7E-235 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 6.9E-259 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 SUPERFAMILY SSF54849 136 204 3.43E-27 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 2.0E-104 T 11-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 UP12_03190 c8573f7f7bcb63dc11ef9da75ec8f1dc 544 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 11-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 Pfam PF00072 Response regulator receiver domain 5 113 2.3E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 222 2.5E-20 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 SUPERFAMILY SSF46894 127 222 8.22E-24 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 SUPERFAMILY SSF52172 3 129 6.4E-32 T 11-10-2018 IPR011006 CheY-like superfamily UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 SMART SM00448 3 113 4.8E-34 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 Gene3D G3DSA:3.40.50.2300 2 129 1.5E-30 T 11-10-2018 UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 SMART SM00862 151 222 3.4E-19 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_15500 53543e248354188bd658d4b0a1d91d1d 225 Gene3D G3DSA:1.10.10.10 130 224 1.6E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 Gene3D G3DSA:3.60.20.10 12 458 1.2E-177 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 PIRSF PIRSF000485 8 473 4.8E-191 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 SUPERFAMILY SSF53271 247 470 1.1E-77 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 SUPERFAMILY SSF56235 12 237 1.46E-70 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 Gene3D G3DSA:3.40.50.2020 271 435 1.2E-177 T 11-10-2018 UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 Pfam PF00156 Phosphoribosyl transferase domain 269 382 3.4E-8 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 456 47.617 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 Pfam PF13522 Glutamine amidotransferase domain 75 205 2.4E-21 T 11-10-2018 UP12_03370 a584f6c86c1cca80d2b0aa07226432f8 476 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 457 2.8E-174 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 UP12_13630 c62c84035c25001de73fdb10e2932506 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 233 248 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 Gene3D G3DSA:3.20.20.100 1 279 4.8E-122 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_13630 c62c84035c25001de73fdb10e2932506 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 SUPERFAMILY SSF51430 3 272 1.44E-92 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_13630 c62c84035c25001de73fdb10e2932506 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 Pfam PF00248 Aldo/keto reductase family 28 265 2.0E-47 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain UP12_13630 c62c84035c25001de73fdb10e2932506 279 PRINTS PR00069 Aldo-keto reductase signature 99 117 5.9E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 PRINTS PR00069 Aldo-keto reductase signature 129 146 5.9E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 PRINTS PR00069 Aldo-keto reductase signature 39 63 5.9E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 PRINTS PR00069 Aldo-keto reductase signature 163 192 5.9E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 PRINTS PR00069 Aldo-keto reductase signature 200 224 5.9E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 PIRSF PIRSF000097 1 123 3.7E-41 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_13630 c62c84035c25001de73fdb10e2932506 279 PIRSF PIRSF000097 119 275 5.7E-50 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 11 342 1.6E-125 T 11-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 1.2E-17 T 11-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 SMART SM00567 E-Z type HEAT repeats 298 327 49.0 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 SMART SM00567 E-Z type HEAT repeats 330 359 0.0055 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 Gene3D G3DSA:1.25.10.10 292 378 3.9E-11 T 11-10-2018 IPR011989 Armadillo-like helical UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 Pfam PF13646 HEAT repeats 300 371 3.1E-13 T 11-10-2018 UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 SUPERFAMILY SSF48371 286 366 2.76E-12 T 11-10-2018 IPR016024 Armadillo-type fold UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 SUPERFAMILY SSF54862 164 250 4.06E-13 T 11-10-2018 UP12_04645 a6b590bd44a1d9d7da21f112fc55f25d 382 Pfam PF13484 4Fe-4S double cluster binding domain 187 250 6.9E-17 T 11-10-2018 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 Pfam PF00318 Ribosomal protein S2 9 223 4.0E-102 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.246 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 6.9E-114 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 11-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 PRINTS PR00395 Ribosomal protein S2 signature 196 210 3.3E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 PRINTS PR00395 Ribosomal protein S2 signature 37 46 3.3E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 PRINTS PR00395 Ribosomal protein S2 signature 6 24 3.3E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 PRINTS PR00395 Ribosomal protein S2 signature 175 186 3.3E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 PRINTS PR00395 Ribosomal protein S2 signature 87 104 3.3E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 PRINTS PR00395 Ribosomal protein S2 signature 158 175 3.3E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 Gene3D G3DSA:1.10.287.610 97 152 2.5E-97 T 11-10-2018 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 SUPERFAMILY SSF52313 6 234 9.03E-102 T 11-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 Gene3D G3DSA:3.40.50.10490 10 214 2.5E-97 T 11-10-2018 UP12_08040 eaaba3e74803cda11f23cfcfd449f61f 244 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 11-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 Gene3D G3DSA:2.30.24.10 1 66 5.2E-20 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 Pfam PF00874 PRD domain 76 163 4.3E-22 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 Pfam PF00874 PRD domain 183 274 2.0E-18 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 Gene3D G3DSA:1.10.1790.10 171 278 6.3E-30 T 11-10-2018 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 SUPERFAMILY SSF50151 2 53 1.96E-14 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 SUPERFAMILY SSF63520 60 167 1.7E-29 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 SUPERFAMILY SSF63520 173 276 1.03E-26 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 Gene3D G3DSA:1.10.1790.10 67 167 2.0E-33 T 11-10-2018 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 SMART SM01061 2 60 2.2E-22 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_18615 d21427daff98f6dfc0d6f57ddb3bf26e 282 Pfam PF03123 CAT RNA binding domain 3 54 2.6E-18 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_06130 ef100a26623e51ac3ee6c7a6c220442e 490 Pfam PF01494 FAD binding domain 10 347 1.5E-9 T 11-10-2018 IPR002938 FAD-binding domain GO:0071949 UP12_06130 ef100a26623e51ac3ee6c7a6c220442e 490 SUPERFAMILY SSF51905 9 353 9.72E-23 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_06130 ef100a26623e51ac3ee6c7a6c220442e 490 Gene3D G3DSA:3.30.9.100 47 303 2.2E-21 T 11-10-2018 UP12_06130 ef100a26623e51ac3ee6c7a6c220442e 490 Gene3D G3DSA:3.50.50.60 11 357 2.2E-21 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_00805 60fadf5662ba377efda51139d718f4f8 120 SUPERFAMILY SSF53137 7 118 9.16E-56 T 11-10-2018 UP12_00805 60fadf5662ba377efda51139d718f4f8 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 2.7E-48 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00805 60fadf5662ba377efda51139d718f4f8 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 4.5E-52 T 11-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00805 60fadf5662ba377efda51139d718f4f8 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 30.273 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00805 60fadf5662ba377efda51139d718f4f8 120 Gene3D G3DSA:3.30.420.100 5 120 1.5E-46 T 11-10-2018 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 33 388 5.8E-18 T 11-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 296 8.6E-76 T 11-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 388 401 1.5E-17 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 83 95 1.5E-17 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 81 1.5E-17 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 1.5E-17 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 198 211 1.5E-17 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 Gene3D G3DSA:2.40.37.10 17 427 1.2E-160 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 235 250 - T 11-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 SUPERFAMILY SSF50621 275 431 4.81E-54 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 316 334 3.0E-30 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 398 420 3.0E-30 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 81 98 3.0E-30 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 PRINTS PR01181 Diaminopimelate decarboxylase signature 170 179 3.0E-30 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 SUPERFAMILY SSF51419 30 299 1.8E-79 T 11-10-2018 IPR029066 PLP-binding barrel UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 19 431 41.894 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 Gene3D G3DSA:3.20.20.10 38 297 1.2E-160 T 11-10-2018 IPR029066 PLP-binding barrel UP12_10510 89db30e01ce4dbb30867d4b94174b70b 441 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 430 1.4E-161 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_19520 1c315220c714fdc2541b00b76df3b244 511 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 288 302 7.4E-8 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_19520 1c315220c714fdc2541b00b76df3b244 511 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 332 345 7.4E-8 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_19520 1c315220c714fdc2541b00b76df3b244 511 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 184 200 7.4E-8 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_19520 1c315220c714fdc2541b00b76df3b244 511 Gene3D G3DSA:3.40.50.150 186 493 1.3E-70 T 11-10-2018 UP12_19520 1c315220c714fdc2541b00b76df3b244 511 Pfam PF00145 C-5 cytosine-specific DNA methylase 184 496 6.1E-52 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_19520 1c315220c714fdc2541b00b76df3b244 511 Gene3D G3DSA:3.90.120.10 327 486 1.3E-70 T 11-10-2018 UP12_19520 1c315220c714fdc2541b00b76df3b244 511 SUPERFAMILY SSF53335 183 498 1.85E-66 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_19520 1c315220c714fdc2541b00b76df3b244 511 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 185 494 1.5E-46 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 SUPERFAMILY SSF52540 11 206 8.8E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 169 6.1E-29 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 Pfam PF07650 KH domain 208 285 9.8E-23 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 4.4E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 4.4E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 Hamap MF_00367 GTPase Era [era]. 6 296 39.34 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 Gene3D G3DSA:3.30.300.20 186 298 2.1E-44 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 SUPERFAMILY SSF54814 182 297 1.37E-43 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 Gene3D G3DSA:3.40.50.300 3 185 1.4E-48 T 11-10-2018 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 279 5.2E-116 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11470 0875a769f24aba9e78d89cf3f3f904d4 301 Pfam PF01926 50S ribosome-binding GTPase 11 125 3.7E-25 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 SMART SM00278 105 124 0.45 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 SMART SM00278 70 89 0.8 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 SUPERFAMILY SSF47781 62 134 2.19E-20 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 Gene3D G3DSA:1.10.8.10 150 199 9.8E-8 T 11-10-2018 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 Gene3D G3DSA:2.40.50.140 1 62 8.9E-16 T 11-10-2018 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 200 2.5E-63 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 Pfam PF07499 RuvA, C-terminal domain 155 199 1.7E-11 T 11-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 SUPERFAMILY SSF50249 2 60 1.37E-13 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 Pfam PF01330 RuvA N terminal domain 2 59 2.8E-17 T 11-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 Pfam PF14520 Helix-hairpin-helix domain 69 126 1.8E-13 T 11-10-2018 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 Gene3D G3DSA:1.10.150.20 63 133 6.1E-24 T 11-10-2018 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 200 27.983 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 UP12_12155 8bd9f143c5a4ae8f3e499a2762d34fc3 201 SUPERFAMILY SSF46929 153 199 9.16E-9 T 11-10-2018 IPR036267 RuvA, C-terminal domain superfamily UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 1.1E-44 T 11-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 Hamap MF_00551 Uridine kinase [udk]. 2 206 41.493 T 11-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 PRINTS PR00988 Uridine kinase signature 5 22 9.8E-36 T 11-10-2018 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 PRINTS PR00988 Uridine kinase signature 35 46 9.8E-36 T 11-10-2018 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 PRINTS PR00988 Uridine kinase signature 150 161 9.8E-36 T 11-10-2018 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 PRINTS PR00988 Uridine kinase signature 136 146 9.8E-36 T 11-10-2018 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 PRINTS PR00988 Uridine kinase signature 80 95 9.8E-36 T 11-10-2018 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 PRINTS PR00988 Uridine kinase signature 172 185 9.8E-36 T 11-10-2018 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 SUPERFAMILY SSF52540 4 197 6.36E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 TIGRFAM TIGR00235 udk: uridine kinase 4 205 1.4E-91 T 11-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 UP12_11930 355f1102d5f89399ddc00b1e809eb889 210 Gene3D G3DSA:3.40.50.300 1 210 7.9E-67 T 11-10-2018 UP12_18775 b5fa3b9bc286f7ddd99d8c0d09f3d500 388 Pfam PF07690 Major Facilitator Superfamily 10 343 9.8E-41 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_18775 b5fa3b9bc286f7ddd99d8c0d09f3d500 388 Gene3D G3DSA:1.20.1250.20 2 378 2.6E-47 T 11-10-2018 UP12_18775 b5fa3b9bc286f7ddd99d8c0d09f3d500 388 SUPERFAMILY SSF103473 7 380 1.96E-56 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF47336 3013 3086 1.96E-18 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.10 3089 3267 1.5E-59 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02005 1ee2e363711070699357bb823375bb11 3564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2673 2684 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.30 1218 1464 5.2E-139 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00550 Phosphopantetheine attachment site 2003 2066 3.2E-14 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00550 Phosphopantetheine attachment site 3024 3081 1.4E-10 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00550 Phosphopantetheine attachment site 966 1028 2.4E-11 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF56801 1492 2014 1.07E-135 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 490 882 3.2E-130 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1518 1915 1.5E-125 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2557 2940 6.4E-119 T 11-10-2018 IPR010071 Amino acid adenylation domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF56801 2498 3034 2.75E-144 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3405 3555 1.1E-46 T 11-10-2018 IPR010060 Non-ribosomal peptide synthase UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.30 2255 2495 1.4E-139 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 1052 1214 6.74E-43 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.40.50.12780 455 852 3.3E-135 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.40.50.12780 1482 1888 1.5E-129 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.40.50.12780 2522 2910 5.5E-119 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 2259 2498 4.56E-54 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF13193 AMP-binding enzyme C-terminal domain 2924 2995 4.1E-11 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 3096 3272 4.11E-37 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.300.30 2911 3009 4.5E-31 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.300.30 853 954 3.2E-29 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.10 2087 2445 1.4E-139 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.30 3268 3537 1.8E-67 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF47336 1994 2098 1.7E-20 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:1.10.1200.10 3010 3088 1.4E-22 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.30 191 446 6.9E-129 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 2089 2251 1.78E-43 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.10 1054 1408 5.2E-139 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.40.50.1820 955 1053 1.4E-21 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF56801 428 972 3.66E-148 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.300.30 1889 1989 2.3E-20 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00668 Condensation domain 3099 3547 8.7E-113 T 11-10-2018 IPR001242 Condensation domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00668 Condensation domain 7 449 1.3E-126 T 11-10-2018 IPR001242 Condensation domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00668 Condensation domain 2082 2515 3.5E-125 T 11-10-2018 IPR001242 Condensation domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00668 Condensation domain 1046 1475 1.7E-129 T 11-10-2018 IPR001242 Condensation domain UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 12 189 3.56E-43 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 191 433 8.89E-50 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 605 616 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00501 AMP-binding enzyme 1497 1894 2.9E-98 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00501 AMP-binding enzyme 2542 2916 3.8E-85 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Pfam PF00501 AMP-binding enzyme 471 858 2.1E-95 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_02005 1ee2e363711070699357bb823375bb11 3564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1636 1647 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_02005 1ee2e363711070699357bb823375bb11 3564 SMART SM00823 Phosphopantetheine attachment site 3021 3089 0.019 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SMART SM00823 Phosphopantetheine attachment site 964 1032 0.0015 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SMART SM00823 Phosphopantetheine attachment site 2001 2070 0.0028 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_02005 1ee2e363711070699357bb823375bb11 3564 ProSitePatterns PS00012 Phosphopantetheine attachment site. 987 1002 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:1.10.1200.10 1990 2072 1.0E-26 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 1221 1467 3.11E-58 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF47336 959 1061 6.02E-15 T 11-10-2018 IPR036736 ACP-like superfamily UP12_02005 1ee2e363711070699357bb823375bb11 3564 SUPERFAMILY SSF52777 3284 3535 6.34E-34 T 11-10-2018 UP12_02005 1ee2e363711070699357bb823375bb11 3564 Gene3D G3DSA:3.30.559.10 12 381 6.9E-129 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_07050 1cec0186d559e4c68df0c0c878f01863 69 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 40 63 3.3E-11 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_07050 1cec0186d559e4c68df0c0c878f01863 69 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 40 62 4.0E-12 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 Gene3D G3DSA:2.40.50.100 1 102 1.8E-27 T 11-10-2018 UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 Pfam PF00364 Biotin-requiring enzyme 4 77 1.4E-23 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 SUPERFAMILY SSF47005 107 151 3.53E-11 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 Pfam PF02817 e3 binding domain 114 147 8.6E-13 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 Gene3D G3DSA:4.10.320.10 104 152 1.1E-15 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 SUPERFAMILY SSF52777 191 410 5.34E-82 T 11-10-2018 UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 Gene3D G3DSA:3.30.559.10 173 418 2.9E-96 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 SUPERFAMILY SSF51230 3 96 2.36E-27 T 11-10-2018 IPR011053 Single hybrid motif UP12_10880 054990a30f7ad32b718015e02ec6ce24 418 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 190 412 6.8E-80 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UP12_10885 b365fe436428ea86500fcdf0c72b4e2a 327 Gene3D G3DSA:3.40.50.920 193 326 1.0E-40 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_10885 b365fe436428ea86500fcdf0c72b4e2a 327 SMART SM00861 4 179 2.8E-71 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_10885 b365fe436428ea86500fcdf0c72b4e2a 327 SUPERFAMILY SSF52922 188 324 2.49E-38 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_10885 b365fe436428ea86500fcdf0c72b4e2a 327 SUPERFAMILY SSF52518 2 204 2.36E-74 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_10885 b365fe436428ea86500fcdf0c72b4e2a 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 4.9E-52 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_10885 b365fe436428ea86500fcdf0c72b4e2a 327 Gene3D G3DSA:3.40.50.970 1 192 9.0E-94 T 11-10-2018 UP12_10885 b365fe436428ea86500fcdf0c72b4e2a 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 3.0E-39 T 11-10-2018 IPR033248 Transketolase, C-terminal domain UP12_07820 6fdc64254faf4999ee951e67f240ce88 254 Pfam PF01351 Ribonuclease HII 73 248 3.0E-36 T 11-10-2018 IPR024567 Ribonuclease HII/HIII domain UP12_07820 6fdc64254faf4999ee951e67f240ce88 254 Gene3D G3DSA:3.30.420.10 47 254 4.8E-79 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_07820 6fdc64254faf4999ee951e67f240ce88 254 Hamap MF_00052_B Ribonuclease HII [rnhB]. 71 249 36.903 T 11-10-2018 IPR022898 Ribonuclease HII GO:0004523 UP12_07820 6fdc64254faf4999ee951e67f240ce88 254 SUPERFAMILY SSF53098 61 253 3.79E-69 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_11180 691482b678bd4b1369005f928b8913ed 97 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 2.2E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site UP12_11180 691482b678bd4b1369005f928b8913ed 97 PIRSF PIRSF029928 1 97 2.1E-32 T 11-10-2018 IPR016940 ComG operon protein C GO:0030420 UP12_11180 691482b678bd4b1369005f928b8913ed 97 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 4.6E-9 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site UP12_11180 691482b678bd4b1369005f928b8913ed 97 Gene3D G3DSA:3.30.700.10 6 94 2.0E-7 T 11-10-2018 UP12_11180 691482b678bd4b1369005f928b8913ed 97 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site UP12_11180 691482b678bd4b1369005f928b8913ed 97 SUPERFAMILY SSF54523 6 68 6.83E-11 T 11-10-2018 UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 64 594 2.3E-179 T 11-10-2018 UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 Gene3D G3DSA:1.10.3810.10 63 254 1.8E-192 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 Pfam PF00912 Transglycosylase 53 227 4.4E-65 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 Gene3D G3DSA:3.90.1310.20 48 501 1.8E-192 T 11-10-2018 UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 Pfam PF00905 Penicillin binding protein transpeptidase domain 320 591 3.0E-42 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 SUPERFAMILY SSF53955 42 250 5.62E-74 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 Gene3D G3DSA:3.40.710.10 293 605 1.8E-192 T 11-10-2018 UP12_05145 83a7e69f9bed84f107ac22f8568496ca 711 SUPERFAMILY SSF56601 209 610 3.0E-102 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_11300 ad8197390429bb9bc437da12cad1bcf9 294 Gene3D G3DSA:1.10.3720.10 57 289 1.4E-35 T 11-10-2018 IPR035906 MetI-like superfamily UP12_11300 ad8197390429bb9bc437da12cad1bcf9 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 292 3.1E-53 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_11300 ad8197390429bb9bc437da12cad1bcf9 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 7 285 1.1E-82 T 11-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 UP12_11300 ad8197390429bb9bc437da12cad1bcf9 294 SUPERFAMILY SSF161098 19 278 1.96E-40 T 11-10-2018 IPR035906 MetI-like superfamily UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 4 479 50.391 T 11-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 Gene3D G3DSA:3.40.50.12780 1 385 3.3E-132 T 11-10-2018 UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 Gene3D G3DSA:3.30.300.310 386 481 4.8E-32 T 11-10-2018 UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 ProSitePatterns PS00455 Putative AMP-binding domain signature. 148 159 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 Pfam PF13193 AMP-binding enzyme C-terminal domain 397 470 1.5E-18 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 Pfam PF00501 AMP-binding enzyme 10 388 1.5E-93 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 SUPERFAMILY SSF56801 5 477 5.23E-138 T 11-10-2018 UP12_13895 21fb3819e4e65e9b5197d2ca3067a608 482 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 29 476 9.8E-165 T 11-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 UP12_03160 9ab01f74af2c4f2d2dd63a81f577d4a8 59 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 58 18.063 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 UP12_03160 9ab01f74af2c4f2d2dd63a81f577d4a8 59 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.9E-6 T 11-10-2018 UP12_03160 9ab01f74af2c4f2d2dd63a81f577d4a8 59 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.9E-6 T 11-10-2018 UP12_03160 9ab01f74af2c4f2d2dd63a81f577d4a8 59 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 48 7.0E-19 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 UP12_03160 9ab01f74af2c4f2d2dd63a81f577d4a8 59 Pfam PF02416 mttA/Hcf106 family 4 55 6.1E-23 T 11-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 UP12_16665 e702b9856cb9efbca653b56735c84abf 219 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 29 219 5.4E-90 T 11-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase UP12_16665 e702b9856cb9efbca653b56735c84abf 219 Pfam PF02397 Bacterial sugar transferase 34 213 7.2E-67 T 11-10-2018 IPR003362 Bacterial sugar transferase UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 Gene3D G3DSA:2.40.50.100 1 101 5.5E-26 T 11-10-2018 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 417 7.1E-177 T 11-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 Pfam PF00364 Biotin-requiring enzyme 3 75 2.5E-23 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 SUPERFAMILY SSF52777 187 416 2.0E-86 T 11-10-2018 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 SUPERFAMILY SSF51230 2 94 1.1E-26 T 11-10-2018 IPR011053 Single hybrid motif UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 SUPERFAMILY SSF47005 116 161 3.27E-9 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 Gene3D G3DSA:3.30.559.10 186 417 5.2E-89 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 Gene3D G3DSA:4.10.320.10 123 161 3.6E-13 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 Pfam PF02817 e3 binding domain 123 156 9.0E-12 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UP12_09525 348e9afe35cd6dbb4fa236f8b3757ae3 418 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 188 416 1.8E-78 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UP12_18105 ce870031508a2576368ad6e8acee369c 217 Gene3D G3DSA:2.60.40.1850 21 153 7.4E-46 T 11-10-2018 UP12_18105 ce870031508a2576368ad6e8acee369c 217 SUPERFAMILY SSF158911 15 157 5.36E-43 T 11-10-2018 IPR037250 NEAT domain superfamily UP12_18105 ce870031508a2576368ad6e8acee369c 217 TIGRFAM TIGR03656 IsdC: heme uptake protein IsdC 1 212 4.0E-63 T 11-10-2018 IPR019909 Haem uptake protein IsdC GO:0009274|GO:0015886|GO:0030492 UP12_18105 ce870031508a2576368ad6e8acee369c 217 Pfam PF05031 Iron Transport-associated domain 29 144 9.6E-38 T 11-10-2018 IPR006635 NEAT domain UP12_18105 ce870031508a2576368ad6e8acee369c 217 SMART SM00725 30 151 2.5E-47 T 11-10-2018 IPR006635 NEAT domain UP12_18105 ce870031508a2576368ad6e8acee369c 217 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 186 212 8.5E-6 T 11-10-2018 IPR017502 Sortase B cell surface sorting signal UP12_05125 e3e9481bc53b8726a3d771642f02b763 235 Pfam PF12787 EcsC protein family 16 231 5.4E-65 T 11-10-2018 IPR024787 EcsC protein UP12_05125 e3e9481bc53b8726a3d771642f02b763 235 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 10 231 3.0E-67 T 11-10-2018 UP12_13215 79a2e4e1849327c8019e4914ff1de875 235 Pfam PF11167 Protein of unknown function (DUF2953) 137 190 3.8E-17 T 11-10-2018 IPR021338 Protein of unknown function DUF2953 UP12_11760 3f92a6d5b3561035b257a2477dd5bc59 541 SUPERFAMILY SSF53067 17 263 2.5E-30 T 11-10-2018 UP12_11760 3f92a6d5b3561035b257a2477dd5bc59 541 Gene3D G3DSA:3.30.420.40 265 529 8.2E-21 T 11-10-2018 UP12_11760 3f92a6d5b3561035b257a2477dd5bc59 541 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 277 474 2.3E-31 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UP12_11760 3f92a6d5b3561035b257a2477dd5bc59 541 Gene3D G3DSA:3.30.420.40 12 264 9.6E-36 T 11-10-2018 UP12_11760 3f92a6d5b3561035b257a2477dd5bc59 541 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 17 260 1.2E-16 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UP12_11760 3f92a6d5b3561035b257a2477dd5bc59 541 SUPERFAMILY SSF53067 272 518 1.12E-14 T 11-10-2018 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 Pfam PF13377 Periplasmic binding protein-like domain 168 329 1.1E-32 T 11-10-2018 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 Gene3D G3DSA:3.40.50.2300 159 289 2.2E-58 T 11-10-2018 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 11-10-2018 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 Gene3D G3DSA:1.10.260.40 1 56 3.2E-22 T 11-10-2018 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 SUPERFAMILY SSF47413 3 60 9.38E-17 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 SMART SM00354 2 72 2.4E-24 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 7.0E-17 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 SUPERFAMILY SSF53822 63 332 7.46E-55 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_01860 7f592655cd165ae47deb0d9edcc5c088 335 Gene3D G3DSA:3.40.50.2300 57 305 2.2E-58 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SUPERFAMILY SSF52440 548 668 4.6E-48 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SUPERFAMILY SSF52440 1 127 8.78E-50 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Gene3D G3DSA:3.40.50.1380 930 1064 3.4E-37 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Pfam PF02142 MGS-like domain 951 1036 5.7E-19 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.225 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SMART SM01096 420 540 1.0E-71 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SUPERFAMILY SSF56059 128 399 1.33E-108 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Gene3D G3DSA:3.30.470.20 120 401 1.8E-124 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Gene3D G3DSA:1.10.1030.10 402 546 3.4E-47 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SMART SM00851 949 1036 5.4E-27 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SUPERFAMILY SSF48108 395 546 3.53E-51 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SUPERFAMILY SSF56059 666 927 6.54E-102 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SMART SM01209 674 836 0.0048 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 2.1E-78 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 667 867 1.3E-40 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Gene3D G3DSA:3.30.470.20 659 929 2.1E-109 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Gene3D G3DSA:3.40.50.20 1 116 2.4E-48 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 3.5E-42 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Gene3D G3DSA:3.40.50.20 547 655 1.6E-46 T 11-10-2018 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.1E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.1E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.1E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.1E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.1E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.1E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.1E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 SUPERFAMILY SSF52335 936 1054 6.93E-32 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07555 e7e401f17aa3dccbfbf2403f93987ad1 1071 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.569 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_00465 7cfe31286855f7d47c6d3e3b06bafc63 112 SUPERFAMILY SSF55620 1 111 1.06E-38 T 11-10-2018 UP12_00465 7cfe31286855f7d47c6d3e3b06bafc63 112 TIGRFAM TIGR00526 folB_dom: FolB domain 1 111 5.4E-36 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UP12_00465 7cfe31286855f7d47c6d3e3b06bafc63 112 SMART SM00905 1 109 1.4E-46 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UP12_00465 7cfe31286855f7d47c6d3e3b06bafc63 112 Gene3D G3DSA:3.30.1130.10 1 112 3.4E-44 T 11-10-2018 UP12_00465 7cfe31286855f7d47c6d3e3b06bafc63 112 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 1 109 1.1E-41 T 11-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UP12_00465 7cfe31286855f7d47c6d3e3b06bafc63 112 Pfam PF02152 Dihydroneopterin aldolase 1 108 3.3E-34 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 UP12_19455 128d5c41c7a814db815da8b81371a4c0 161 PIRSF PIRSF002070 1 151 5.4E-42 T 11-10-2018 UP12_19455 128d5c41c7a814db815da8b81371a4c0 161 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 161 6.4E-53 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UP12_19455 128d5c41c7a814db815da8b81371a4c0 161 Pfam PF00436 Single-strand binding protein family 2 103 3.9E-38 T 11-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 UP12_19455 128d5c41c7a814db815da8b81371a4c0 161 Gene3D G3DSA:2.40.50.140 1 111 1.4E-46 T 11-10-2018 UP12_19455 128d5c41c7a814db815da8b81371a4c0 161 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 36.836 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UP12_19455 128d5c41c7a814db815da8b81371a4c0 161 SUPERFAMILY SSF50249 1 161 3.77E-57 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 38.809 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 SUPERFAMILY SSF53335 4 309 3.06E-46 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 310 8.9E-132 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 Pfam PF01795 MraW methylase family 2 310 8.0E-136 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 Gene3D G3DSA:1.10.150.170 111 215 1.7E-106 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 Gene3D G3DSA:3.40.50.150 7 309 1.7E-106 T 11-10-2018 UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 SUPERFAMILY SSF81799 113 214 4.19E-36 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 UP12_07340 dd84d7bd6cabd80bf92cb8b996222f1b 310 PIRSF PIRSF004486 1 310 4.9E-111 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 Pfam PF04542 Sigma-70 region 2 43 111 6.4E-17 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 SUPERFAMILY SSF88659 176 257 3.92E-16 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_07435 39c478428cc40566e00ee7eec07672cc 259 Gene3D G3DSA:1.10.10.10 112 165 2.1E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PRINTS PR00046 Major sigma-70 factor signature 67 80 2.3E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PRINTS PR00046 Major sigma-70 factor signature 211 223 2.3E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PRINTS PR00046 Major sigma-70 factor signature 243 254 2.3E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PRINTS PR00046 Major sigma-70 factor signature 228 243 2.3E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PRINTS PR00046 Major sigma-70 factor signature 91 99 2.3E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 228 254 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 Gene3D G3DSA:1.20.120.1810 3 111 4.9E-27 T 11-10-2018 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 SUPERFAMILY SSF88659 115 191 2.7E-16 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_07435 39c478428cc40566e00ee7eec07672cc 259 Pfam PF04545 Sigma-70, region 4 208 254 3.1E-13 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 258 1.6E-156 T 11-10-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 67 80 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 SUPERFAMILY SSF88946 14 111 5.49E-33 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 Gene3D G3DSA:1.10.10.10 186 258 1.7E-9 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_07435 39c478428cc40566e00ee7eec07672cc 259 Pfam PF04539 Sigma-70 region 3 125 176 1.6E-6 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PIRSF PIRSF000770 15 123 3.8E-17 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PIRSF PIRSF000770 160 259 6.1E-14 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 PIRSF PIRSF000770 124 158 2.7 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 1.2E-83 T 11-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_07435 39c478428cc40566e00ee7eec07672cc 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 257 7.3E-35 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 SUPERFAMILY SSF52335 1 129 2.01E-51 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 Gene3D G3DSA:3.40.50.1380 1 136 1.2E-55 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 11-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 PIRSF PIRSF006614 1 138 1.6E-59 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 121 7.4E-60 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 Pfam PF02142 MGS-like domain 15 107 2.2E-17 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 34.079 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 UP12_10080 2bb7ce4244e9a0c02f6141227face9e6 139 SMART SM00851 14 107 1.7E-22 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 151 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 117 125 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 245 266 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 52 67 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 206 222 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 7.4E-70 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 Gene3D G3DSA:3.50.50.60 19 312 8.1E-113 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 4.4E-34 T 11-10-2018 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 4.4E-34 T 11-10-2018 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 4.4E-34 T 11-10-2018 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 4.4E-34 T 11-10-2018 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 4.4E-34 T 11-10-2018 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 316 5.4E-120 T 11-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 SUPERFAMILY SSF51905 11 313 7.56E-53 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 146 166 - T 11-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 18 305 2.4E-49 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_16230 b6fc4ff9f538b40c64cb51773bb3ed07 327 Gene3D G3DSA:3.50.50.60 128 251 8.1E-113 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_06290 72ec5496809e6eb1869c697a3bc45f98 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 298 2.0E-19 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_06290 72ec5496809e6eb1869c697a3bc45f98 336 SUPERFAMILY SSF52540 35 326 4.55E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06290 72ec5496809e6eb1869c697a3bc45f98 336 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_06290 72ec5496809e6eb1869c697a3bc45f98 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 2.4E-26 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_06290 72ec5496809e6eb1869c697a3bc45f98 336 SMART SM00382 33 233 2.7E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_06290 72ec5496809e6eb1869c697a3bc45f98 336 Gene3D G3DSA:3.40.50.300 1 333 1.1E-99 T 11-10-2018 UP12_06290 72ec5496809e6eb1869c697a3bc45f98 336 Pfam PF00005 ABC transporter 25 183 1.0E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 TIGRFAM TIGR01314 gntK_FGGY: gluconate kinase 7 509 9.5E-203 T 11-10-2018 IPR006002 Gluconate kinase GO:0019521|GO:0046316 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 Gene3D G3DSA:3.30.420.40 252 514 2.9E-92 T 11-10-2018 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 Gene3D G3DSA:3.30.420.40 3 251 1.6E-82 T 11-10-2018 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 SUPERFAMILY SSF53067 252 501 3.35E-68 T 11-10-2018 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 SUPERFAMILY SSF53067 7 253 4.12E-71 T 11-10-2018 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 PIRSF PIRSF000538 4 505 2.8E-153 T 11-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 250 4.1E-75 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UP12_18465 a2e92bf1995027aefaa0d90f6a15fe28 514 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 454 3.3E-36 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UP12_01835 e38fa386b1e8ad9402ea2d6ea6c9c56b 438 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 33 427 2.5E-120 T 11-10-2018 UP12_01835 e38fa386b1e8ad9402ea2d6ea6c9c56b 438 Gene3D G3DSA:1.20.1250.20 234 433 1.0E-29 T 11-10-2018 UP12_01835 e38fa386b1e8ad9402ea2d6ea6c9c56b 438 PIRSF PIRSF002808 7 437 3.8E-37 T 11-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 UP12_01835 e38fa386b1e8ad9402ea2d6ea6c9c56b 438 Gene3D G3DSA:1.20.1250.20 17 212 1.2E-46 T 11-10-2018 UP12_01835 e38fa386b1e8ad9402ea2d6ea6c9c56b 438 SUPERFAMILY SSF103473 17 433 1.06E-82 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01835 e38fa386b1e8ad9402ea2d6ea6c9c56b 438 Pfam PF07690 Major Facilitator Superfamily 30 392 1.4E-59 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 308 406 2.1E-19 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 286 3.5E-85 T 11-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 66 77 7.1E-15 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 150 163 7.1E-15 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 123 140 7.1E-15 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 Gene3D G3DSA:2.60.410.10 309 411 2.5E-20 T 11-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 Gene3D G3DSA:3.40.710.10 28 308 2.1E-89 T 11-10-2018 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 SUPERFAMILY SSF69189 300 389 3.34E-19 T 11-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_00075 77775da9281403cfadad32e0c7ab069a 441 SUPERFAMILY SSF56601 12 308 1.51E-76 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_00075 77775da9281403cfadad32e0c7ab069a 441 SMART SM00936 308 411 1.8E-21 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_06295 2c949dd3b5457c786103943220ad35fc 540 Gene3D G3DSA:3.10.105.10 293 511 5.9E-165 T 11-10-2018 UP12_06295 2c949dd3b5457c786103943220ad35fc 540 SUPERFAMILY SSF53850 37 533 1.63E-130 T 11-10-2018 UP12_06295 2c949dd3b5457c786103943220ad35fc 540 Gene3D G3DSA:3.40.190.10 50 525 5.9E-165 T 11-10-2018 UP12_06295 2c949dd3b5457c786103943220ad35fc 540 Gene3D G3DSA:3.90.76.10 71 193 5.9E-165 T 11-10-2018 UP12_06295 2c949dd3b5457c786103943220ad35fc 540 PIRSF PIRSF002741 1 537 4.5E-120 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UP12_06295 2c949dd3b5457c786103943220ad35fc 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 461 4.9E-84 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain UP12_06295 2c949dd3b5457c786103943220ad35fc 540 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 87 109 - T 11-10-2018 IPR023765 Solute-binding protein family 5, conserved site UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 Gene3D G3DSA:2.60.40.1180 485 568 5.0E-23 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 SUPERFAMILY SSF51445 10 481 4.08E-151 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 SUPERFAMILY SSF51011 484 565 1.52E-17 T 11-10-2018 UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 Pfam PF00128 Alpha amylase, catalytic domain 34 383 1.3E-126 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 SMART SM00642 19 425 1.7E-155 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 Gene3D G3DSA:3.20.20.80 11 476 1.2E-194 T 11-10-2018 UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 Pfam PF16657 Maltogenic Amylase, C-terminal domain 484 559 1.3E-9 T 11-10-2018 IPR032091 Maltogenic Amylase, C-terminal UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 11 564 1.8E-254 T 11-10-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 UP12_03960 d53f0d817c4d4f3f90aef5825748e625 568 Gene3D G3DSA:3.90.400.10 111 181 1.2E-194 T 11-10-2018 UP12_13760 62fdbec3694b4ca6995c1a05d8d8cfbf 493 Pfam PF01593 Flavin containing amine oxidoreductase 11 489 1.6E-26 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UP12_13760 62fdbec3694b4ca6995c1a05d8d8cfbf 493 Gene3D G3DSA:3.50.50.60 1 106 4.0E-26 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_13760 62fdbec3694b4ca6995c1a05d8d8cfbf 493 Gene3D G3DSA:3.50.50.60 199 325 1.1E-14 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_13760 62fdbec3694b4ca6995c1a05d8d8cfbf 493 SUPERFAMILY SSF51905 1 492 2.28E-63 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_13760 62fdbec3694b4ca6995c1a05d8d8cfbf 493 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 4 491 1.3E-113 T 11-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 UP12_06880 409a1c2c286da2546d48ecb64763edcb 80 Hamap MF_00506 UPF0180 protein . 1 79 26.1 T 11-10-2018 IPR005370 Uncharacterised protein family UPF0180 UP12_06880 409a1c2c286da2546d48ecb64763edcb 80 Pfam PF03698 Uncharacterised protein family (UPF0180) 3 78 3.1E-30 T 11-10-2018 IPR005370 Uncharacterised protein family UPF0180 UP12_06880 409a1c2c286da2546d48ecb64763edcb 80 ProDom PD059670 UPF0180 YKUS BA1413/GBAA1413/BAS1304 YKUS-LIKE BT9727_1277 BCE1513 GK1051 BH2667 ABC2430 BCE33L1278 1 47 2.0E-11 T 11-10-2018 IPR005370 Uncharacterised protein family UPF0180 UP12_02125 d686d96faece087f241c6659280cec2d 385 Gene3D G3DSA:3.40.630.10 13 364 1.0E-132 T 11-10-2018 UP12_02125 d686d96faece087f241c6659280cec2d 385 Gene3D G3DSA:3.30.70.360 180 294 1.0E-132 T 11-10-2018 UP12_02125 d686d96faece087f241c6659280cec2d 385 Pfam PF07687 Peptidase dimerisation domain 184 276 1.4E-11 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain UP12_02125 d686d96faece087f241c6659280cec2d 385 SUPERFAMILY SSF53187 8 380 5.69E-82 T 11-10-2018 UP12_02125 d686d96faece087f241c6659280cec2d 385 Pfam PF01546 Peptidase family M20/M25/M40 72 375 1.8E-36 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_02125 d686d96faece087f241c6659280cec2d 385 SUPERFAMILY SSF55031 182 295 5.63E-30 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_02125 d686d96faece087f241c6659280cec2d 385 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 13 367 6.2E-121 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_02125 d686d96faece087f241c6659280cec2d 385 PIRSF PIRSF005962 3 383 5.8E-123 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_03240 0f7682160af6d4e7bd492cf749631468 509 Gene3D G3DSA:2.60.40.420 174 352 1.4E-65 T 11-10-2018 IPR008972 Cupredoxin UP12_03240 0f7682160af6d4e7bd492cf749631468 509 SUPERFAMILY SSF49503 3 174 1.91E-33 T 11-10-2018 IPR008972 Cupredoxin UP12_03240 0f7682160af6d4e7bd492cf749631468 509 Gene3D G3DSA:2.60.40.420 358 509 3.7E-51 T 11-10-2018 IPR008972 Cupredoxin UP12_03240 0f7682160af6d4e7bd492cf749631468 509 SUPERFAMILY SSF49503 180 309 2.16E-28 T 11-10-2018 IPR008972 Cupredoxin UP12_03240 0f7682160af6d4e7bd492cf749631468 509 Gene3D G3DSA:2.60.40.420 1 172 9.9E-67 T 11-10-2018 IPR008972 Cupredoxin UP12_03240 0f7682160af6d4e7bd492cf749631468 509 SUPERFAMILY SSF49503 359 508 6.45E-32 T 11-10-2018 IPR008972 Cupredoxin UP12_03240 0f7682160af6d4e7bd492cf749631468 509 Pfam PF07731 Multicopper oxidase 372 506 1.7E-21 T 11-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 UP12_03240 0f7682160af6d4e7bd492cf749631468 509 Pfam PF07732 Multicopper oxidase 99 174 2.5E-6 T 11-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UP12_03240 0f7682160af6d4e7bd492cf749631468 509 Pfam PF07732 Multicopper oxidase 45 79 3.1E-6 T 11-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 UP12_03240 0f7682160af6d4e7bd492cf749631468 509 Pfam PF00394 Multicopper oxidase 242 309 1.0E-5 T 11-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 UP12_02750 b9a5c69ca68839c660a32abdb2f4b86f 411 Gene3D G3DSA:3.40.50.300 162 356 1.1E-38 T 11-10-2018 UP12_02750 b9a5c69ca68839c660a32abdb2f4b86f 411 SUPERFAMILY SSF52540 58 309 3.27E-28 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02750 b9a5c69ca68839c660a32abdb2f4b86f 411 Gene3D G3DSA:3.30.450.380 2 158 2.4E-13 T 11-10-2018 UP12_02750 b9a5c69ca68839c660a32abdb2f4b86f 411 Pfam PF00437 Type II/IV secretion system protein 76 319 7.5E-33 T 11-10-2018 IPR001482 Type II/IV secretion system protein UP12_15125 a67de0484db74947296046ca807984ea 332 Gene3D G3DSA:3.50.50.60 128 246 2.7E-120 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 2.8E-16 T 11-10-2018 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.8E-16 T 11-10-2018 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 2.8E-16 T 11-10-2018 UP12_15125 a67de0484db74947296046ca807984ea 332 Gene3D G3DSA:3.50.50.60 7 304 2.7E-120 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_15125 a67de0484db74947296046ca807984ea 332 SUPERFAMILY SSF51905 8 314 3.56E-40 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_15125 a67de0484db74947296046ca807984ea 332 Hamap MF_01685 Ferredoxin--NADP reductase. 7 328 44.42 T 11-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 1.2E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.2E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 1.2E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 1.2E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 1.2E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_15125 a67de0484db74947296046ca807984ea 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 1.2E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_15125 a67de0484db74947296046ca807984ea 332 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 293 9.0E-30 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_11840 31c130c844054f907034fed0bad62349 346 Gene3D G3DSA:3.40.50.720 156 291 8.3E-99 T 11-10-2018 UP12_11840 31c130c844054f907034fed0bad62349 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 137 7.5E-26 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_11840 31c130c844054f907034fed0bad62349 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 69 83 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UP12_11840 31c130c844054f907034fed0bad62349 346 Gene3D G3DSA:3.90.180.10 9 326 8.3E-99 T 11-10-2018 UP12_11840 31c130c844054f907034fed0bad62349 346 Pfam PF00107 Zinc-binding dehydrogenase 179 304 2.4E-25 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_11840 31c130c844054f907034fed0bad62349 346 SUPERFAMILY SSF50129 1 178 1.73E-48 T 11-10-2018 IPR011032 GroES-like superfamily UP12_11840 31c130c844054f907034fed0bad62349 346 SUPERFAMILY SSF51735 143 309 6.69E-39 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_11840 31c130c844054f907034fed0bad62349 346 SMART SM00829 7 343 7.1E-5 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_15075 4b251ff5e679a4be2d870e75ca37e6b7 409 Gene3D G3DSA:3.30.450.40 4 156 2.3E-6 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_15075 4b251ff5e679a4be2d870e75ca37e6b7 409 SUPERFAMILY SSF55781 15 148 3.43E-6 T 11-10-2018 UP12_15075 4b251ff5e679a4be2d870e75ca37e6b7 409 Gene3D G3DSA:1.10.10.2840 275 408 1.5E-17 T 11-10-2018 UP12_15075 4b251ff5e679a4be2d870e75ca37e6b7 409 Pfam PF13556 PucR C-terminal helix-turn-helix domain 346 403 9.8E-17 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_15075 4b251ff5e679a4be2d870e75ca37e6b7 409 Pfam PF06018 CodY GAF-like domain 16 157 3.4E-7 T 11-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 UP12_06310 5f5fb7738f870a4e15198013e5334bdf 305 Pfam PF00877 NlpC/P60 family 187 293 3.0E-24 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_06310 5f5fb7738f870a4e15198013e5334bdf 305 Gene3D G3DSA:2.30.30.40 4 107 4.3E-34 T 11-10-2018 UP12_06310 5f5fb7738f870a4e15198013e5334bdf 305 Gene3D G3DSA:3.90.1720.10 116 286 8.5E-36 T 11-10-2018 UP12_06310 5f5fb7738f870a4e15198013e5334bdf 305 SUPERFAMILY SSF54001 167 296 7.19E-37 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_05035 f6bc9a059d8327abb1777219538a3e5f 62 Pfam PF14120 YhzD-like protein 2 62 1.4E-28 T 11-10-2018 IPR025544 YhzD-like protein UP12_05320 d706d6c16825557aca614b84a3314447 1232 SUPERFAMILY SSF52540 3 888 4.28E-121 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05320 d706d6c16825557aca614b84a3314447 1232 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1052 1223 5.1E-11 T 11-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type UP12_05320 d706d6c16825557aca614b84a3314447 1232 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 8 1232 20.179 T 11-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 UP12_05320 d706d6c16825557aca614b84a3314447 1232 Gene3D G3DSA:3.40.50.300 268 475 4.5E-32 T 11-10-2018 UP12_05320 d706d6c16825557aca614b84a3314447 1232 Gene3D G3DSA:3.40.50.300 2 193 1.2E-40 T 11-10-2018 UP12_05320 d706d6c16825557aca614b84a3314447 1232 Gene3D G3DSA:3.90.320.10 990 1230 1.3E-76 T 11-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal UP12_05320 d706d6c16825557aca614b84a3314447 1232 SUPERFAMILY SSF52980 1014 1224 5.09E-39 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UP12_05320 d706d6c16825557aca614b84a3314447 1232 Gene3D G3DSA:3.40.50.300 758 959 8.7E-49 T 11-10-2018 UP12_05320 d706d6c16825557aca614b84a3314447 1232 Gene3D G3DSA:3.40.50.300 476 757 3.7E-58 T 11-10-2018 UP12_05320 d706d6c16825557aca614b84a3314447 1232 Pfam PF13361 UvrD-like helicase C-terminal domain 473 883 5.5E-33 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UP12_05320 d706d6c16825557aca614b84a3314447 1232 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 463 4.4E-94 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UP12_05320 d706d6c16825557aca614b84a3314447 1232 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 10 1230 0.0 T 11-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 UP12_09125 5846ade60cd3847acc9e347f0ba109b4 509 Gene3D G3DSA:3.90.226.10 245 508 1.3E-83 T 11-10-2018 UP12_09125 5846ade60cd3847acc9e347f0ba109b4 509 SUPERFAMILY SSF52096 4 247 3.27E-68 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_09125 5846ade60cd3847acc9e347f0ba109b4 509 Gene3D G3DSA:3.90.226.10 2 244 3.0E-79 T 11-10-2018 UP12_09125 5846ade60cd3847acc9e347f0ba109b4 509 SUPERFAMILY SSF52096 211 489 4.7E-81 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_09125 5846ade60cd3847acc9e347f0ba109b4 509 Pfam PF01039 Carboxyl transferase domain 26 506 2.7E-161 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 UP12_05790 0a514ae29a4aca759d0e0b33c922d001 266 Pfam PF01513 ATP-NAD kinase 23 210 2.1E-25 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UP12_05790 0a514ae29a4aca759d0e0b33c922d001 266 Gene3D G3DSA:3.40.50.10330 16 262 2.0E-98 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UP12_05790 0a514ae29a4aca759d0e0b33c922d001 266 Gene3D G3DSA:2.60.200.30 102 240 2.0E-98 T 11-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UP12_05790 0a514ae29a4aca759d0e0b33c922d001 266 SUPERFAMILY SSF111331 20 261 9.29E-64 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UP12_05790 0a514ae29a4aca759d0e0b33c922d001 266 Hamap MF_00361 NAD kinase [nadK]. 1 263 23.501 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UP12_01595 04dffe84cdeb931eacb9b8ccc501d7a2 391 Pfam PF12679 ABC-2 family transporter protein 4 387 2.6E-35 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UP12_04250 eab22597ac29f787ed9455a0324d9661 159 Pfam PF01047 MarR family 48 104 1.3E-18 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_04250 eab22597ac29f787ed9455a0324d9661 159 Gene3D G3DSA:1.10.10.10 15 155 3.7E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04250 eab22597ac29f787ed9455a0324d9661 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 3.0E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_04250 eab22597ac29f787ed9455a0324d9661 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 3.0E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_04250 eab22597ac29f787ed9455a0324d9661 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 3.0E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_04250 eab22597ac29f787ed9455a0324d9661 159 SUPERFAMILY SSF46785 41 154 4.39E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_04250 eab22597ac29f787ed9455a0324d9661 159 SMART SM00347 40 140 5.0E-34 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 SUPERFAMILY SSF52518 1 178 1.53E-50 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 Gene3D G3DSA:3.40.50.970 2 202 1.2E-58 T 11-10-2018 UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 SUPERFAMILY SSF52467 160 366 2.5E-47 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 175 1.3E-55 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 337 6.3E-39 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 440 459 - T 11-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 Gene3D G3DSA:3.40.50.1220 203 368 1.5E-110 T 11-10-2018 UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 405 555 7.6E-42 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 SUPERFAMILY SSF52518 380 562 5.72E-57 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_01820 8ad503f83243c3435f53f2e915a95bd9 586 Gene3D G3DSA:3.40.50.970 373 555 1.5E-110 T 11-10-2018 UP12_13475 42b5e43ae8e44b1d956a8ccc893ac9d4 357 Gene3D G3DSA:2.40.30.40 75 162 2.8E-115 T 11-10-2018 IPR023367 Peptidase M42, domain 2 UP12_13475 42b5e43ae8e44b1d956a8ccc893ac9d4 357 Pfam PF05343 M42 glutamyl aminopeptidase 46 337 3.7E-109 T 11-10-2018 IPR008007 Peptidase M42 UP12_13475 42b5e43ae8e44b1d956a8ccc893ac9d4 357 SUPERFAMILY SSF101821 71 180 9.92E-31 T 11-10-2018 UP12_13475 42b5e43ae8e44b1d956a8ccc893ac9d4 357 Gene3D G3DSA:3.40.630.10 11 339 2.8E-115 T 11-10-2018 UP12_13475 42b5e43ae8e44b1d956a8ccc893ac9d4 357 SUPERFAMILY SSF53187 4 351 2.28E-69 T 11-10-2018 UP12_13475 42b5e43ae8e44b1d956a8ccc893ac9d4 357 PIRSF PIRSF001123 2 356 1.4E-147 T 11-10-2018 IPR008007 Peptidase M42 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 SUPERFAMILY SSF52540 487 803 7.34E-81 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00580 412f1d99bbe72e1501e96030a015368b 811 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 7.3E-16 T 11-10-2018 IPR004176 Clp, N-terminal UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 144 2.0E-18 T 11-10-2018 IPR004176 Clp, N-terminal UP12_00580 412f1d99bbe72e1501e96030a015368b 811 SMART SM01086 715 804 7.8E-36 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Gene3D G3DSA:3.40.50.300 490 713 2.6E-90 T 11-10-2018 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Gene3D G3DSA:1.10.8.60 347 482 1.3E-53 T 11-10-2018 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Pfam PF02151 UvrB/uvrC motif 418 452 8.9E-7 T 11-10-2018 IPR001943 UVR domain GO:0005515 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 SMART SM00382 201 344 4.0E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00580 412f1d99bbe72e1501e96030a015368b 811 SMART SM00382 538 716 1.7E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00580 412f1d99bbe72e1501e96030a015368b 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 587 605 6.1E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 649 663 6.1E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 616 634 6.1E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 542 560 6.1E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 SUPERFAMILY SSF52540 162 466 9.16E-77 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Pfam PF07724 AAA domain (Cdc48 subfamily) 537 709 1.8E-57 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Gene3D G3DSA:1.10.1780.10 1 151 9.0E-61 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 715 794 1.3E-25 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Gene3D G3DSA:3.40.50.300 152 344 1.1E-71 T 11-10-2018 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Gene3D G3DSA:1.10.8.60 715 810 4.7E-28 T 11-10-2018 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 206 318 1.7E-13 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 572 590 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 SUPERFAMILY SSF81923 5 147 2.26E-31 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 UP12_00580 412f1d99bbe72e1501e96030a015368b 811 Gene3D G3DSA:4.10.860.10 410 468 1.3E-53 T 11-10-2018 UP12_17820 a26ae30485b56eb4f4e5915c894c741f 360 Gene3D G3DSA:3.40.350.10 2 124 6.2E-11 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UP12_17820 a26ae30485b56eb4f4e5915c894c741f 360 Gene3D G3DSA:3.90.230.10 125 337 5.0E-18 T 11-10-2018 UP12_17820 a26ae30485b56eb4f4e5915c894c741f 360 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 107 8.8E-12 T 11-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 UP12_17820 a26ae30485b56eb4f4e5915c894c741f 360 SUPERFAMILY SSF55920 126 338 8.51E-20 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like UP12_17820 a26ae30485b56eb4f4e5915c894c741f 360 SUPERFAMILY SSF53092 2 108 1.29E-10 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UP12_17820 a26ae30485b56eb4f4e5915c894c741f 360 Pfam PF00557 Metallopeptidase family M24 140 325 2.0E-9 T 11-10-2018 IPR000994 Peptidase M24 UP12_11545 1ec60c77a54f8d0200d1b94b74a2a95b 256 Pfam PF04452 RNA methyltransferase 20 247 4.0E-74 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 UP12_11545 1ec60c77a54f8d0200d1b94b74a2a95b 256 PIRSF PIRSF015601 1 251 2.9E-61 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 UP12_11545 1ec60c77a54f8d0200d1b94b74a2a95b 256 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 251 1.3E-74 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 UP12_11545 1ec60c77a54f8d0200d1b94b74a2a95b 256 SUPERFAMILY SSF75217 75 251 7.41E-54 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases UP12_11545 1ec60c77a54f8d0200d1b94b74a2a95b 256 SUPERFAMILY SSF88697 2 71 2.26E-13 T 11-10-2018 IPR015947 PUA-like superfamily UP12_11545 1ec60c77a54f8d0200d1b94b74a2a95b 256 Gene3D G3DSA:3.40.1280.10 1 256 2.9E-92 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UP12_02065 6c3b85ebf78cc4b0e98a93070c51fbc1 100 SUPERFAMILY SSF89447 12 55 1.18E-11 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily UP12_02065 6c3b85ebf78cc4b0e98a93070c51fbc1 100 SMART SM00966 14 59 0.0023 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_02065 6c3b85ebf78cc4b0e98a93070c51fbc1 100 Gene3D G3DSA:2.10.260.10 9 60 1.2E-15 T 11-10-2018 UP12_02065 6c3b85ebf78cc4b0e98a93070c51fbc1 100 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 16 54 2.4E-8 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 Gene3D G3DSA:3.50.30.20 1 147 1.6E-57 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00097 Anthranilate synthase component II signature 214 223 1.3E-6 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00097 Anthranilate synthase component II signature 241 252 1.3E-6 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00097 Anthranilate synthase component II signature 325 338 1.3E-6 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 9.3E-37 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 9.3E-37 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 9.3E-37 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 9.3E-37 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 9.3E-37 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 SUPERFAMILY SSF52317 141 351 8.07E-58 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 354 49.045 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 SUPERFAMILY SSF52021 1 142 6.02E-58 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 7.3E-12 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 325 338 7.3E-12 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 7.3E-12 T 11-10-2018 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 Gene3D G3DSA:3.40.50.880 164 360 5.2E-36 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 351 1.8E-146 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 SMART SM01097 1 131 1.2E-91 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 Pfam PF00117 Glutamine amidotransferase class-I 174 348 9.0E-46 T 11-10-2018 IPR017926 Glutamine amidotransferase UP12_07550 00b352ee45de9bfe31c740db23fb7f3e 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 5.1E-54 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 Pfam PF13167 GTP-binding GTPase N-terminal 27 114 3.3E-33 T 11-10-2018 IPR025121 GTPase HflX, N-terminal UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 SUPERFAMILY SSF52540 199 362 4.86E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 Gene3D G3DSA:3.40.50.300 201 367 7.2E-35 T 11-10-2018 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 200 356 1.0E-11 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 Gene3D G3DSA:3.40.50.11060 20 140 6.4E-41 T 11-10-2018 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 202 222 7.8E-9 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 269 287 7.8E-9 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 PIRSF PIRSF006809 1 419 1.2E-148 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 Pfam PF01926 50S ribosome-binding GTPase 201 320 6.9E-21 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 Hamap MF_00900 GTPase HflX [hflX]. 29 388 47.344 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 Pfam PF16360 GTP-binding GTPase Middle Region 116 194 1.5E-30 T 11-10-2018 IPR032305 GTP-binding protein, middle domain UP12_08485 155ac9424a342aca0a02b93eb3a32d21 420 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 9 356 7.6E-146 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 509 526 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 573 589 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 38 53 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 529 541 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 73 86 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 269 282 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 425 439 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR00418 DNA topoisomerase II family signature 491 507 5.0E-70 T 11-10-2018 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 7 639 48.389 T 11-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 SUPERFAMILY SSF56719 399 634 7.06E-87 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Gene3D G3DSA:3.40.50.670 411 643 2.3E-102 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Gene3D G3DSA:3.30.565.10 6 221 2.3E-88 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 9 19 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 183 198 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 377 397 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 313 329 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 610 626 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 198 211 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 475 484 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 222 244 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 363 377 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 PRINTS PR01159 DNA gyrase subunit B signature 594 606 2.7E-57 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Pfam PF01751 Toprim domain 424 527 1.0E-16 T 11-10-2018 IPR006171 TOPRIM domain UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 SUPERFAMILY SSF54211 223 393 1.1E-52 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 8 643 0.0 T 11-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 175 1.1E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Pfam PF00204 DNA gyrase B 223 393 1.6E-58 T 11-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 SMART SM00387 34 178 8.4E-25 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 630 2.2E-30 T 11-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 Gene3D G3DSA:3.30.230.10 222 403 1.4E-70 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 SMART SM00433 38 634 0.0 T 11-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 SUPERFAMILY SSF55874 9 220 4.85E-69 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_08800 69f0bcb07d4cb1ece719fae9506b37f8 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 427 435 - T 11-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_17260 52a950c588131ac39aff601aa0dbdde2 218 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 5 170 4.6E-67 T 11-10-2018 IPR014202 Sporulation stage II, protein R UP12_17260 52a950c588131ac39aff601aa0dbdde2 218 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 41 166 7.0E-48 T 11-10-2018 IPR014202 Sporulation stage II, protein R UP12_13340 f5a7613774cc7dbfb3ac4cf4db152a38 567 Pfam PF06160 Septation ring formation regulator, EzrA 3 558 3.2E-174 T 11-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 UP12_13340 f5a7613774cc7dbfb3ac4cf4db152a38 567 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 563 22.45 T 11-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 UP12_07100 fb7bd84b5c78a5fe54ccb4a8e6f605bc 211 PIRSF PIRSF021332 1 209 3.4E-89 T 11-10-2018 IPR009403 Protein of unknown function UPF0637 UP12_07100 fb7bd84b5c78a5fe54ccb4a8e6f605bc 211 Hamap MF_01851 UPF0637 protein . 5 205 37.935 T 11-10-2018 IPR009403 Protein of unknown function UPF0637 UP12_07100 fb7bd84b5c78a5fe54ccb4a8e6f605bc 211 SUPERFAMILY SSF142913 4 209 1.2E-85 T 11-10-2018 UP12_07100 fb7bd84b5c78a5fe54ccb4a8e6f605bc 211 Pfam PF06335 Protein of unknown function (DUF1054) 6 203 1.2E-85 T 11-10-2018 IPR009403 Protein of unknown function UPF0637 UP12_07100 fb7bd84b5c78a5fe54ccb4a8e6f605bc 211 Gene3D G3DSA:3.30.930.20 1 211 5.7E-90 T 11-10-2018 UP12_09270 19b716f4a3fb640bfe1c4125fb40d595 326 Gene3D G3DSA:2.160.20.10 28 326 4.6E-109 T 11-10-2018 IPR012334 Pectin lyase fold UP12_09270 19b716f4a3fb640bfe1c4125fb40d595 326 SUPERFAMILY SSF51126 31 322 2.16E-83 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_09270 19b716f4a3fb640bfe1c4125fb40d595 326 ProSitePatterns PS00800 Pectinesterase signature 1. 59 78 - T 11-10-2018 IPR018040 Pectinesterase, Tyr active site KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 UP12_09270 19b716f4a3fb640bfe1c4125fb40d595 326 Pfam PF01095 Pectinesterase 36 317 1.2E-73 T 11-10-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 UP12_09270 19b716f4a3fb640bfe1c4125fb40d595 326 ProSitePatterns PS00503 Pectinesterase signature 2. 179 188 - T 11-10-2018 IPR033131 Pectinesterase, Asp active site KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 Pfam PF01565 FAD binding domain 35 164 7.3E-23 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 2.5E-28 T 11-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 Gene3D G3DSA:3.90.78.10 217 303 2.8E-34 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 Gene3D G3DSA:3.30.43.10 1 88 4.8E-28 T 11-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 SUPERFAMILY SSF56194 197 301 3.53E-36 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 303 90.809 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 Gene3D G3DSA:3.30.465.10 89 216 3.2E-49 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 SUPERFAMILY SSF56176 14 193 6.91E-44 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UP12_07385 1424f8bd71e01ac3dd6dea3ae1899df6 303 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 2.0E-108 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SUPERFAMILY SSF55785 103 215 2.44E-15 T 11-10-2018 IPR035965 PAS domain superfamily UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Gene3D G3DSA:3.40.50.720 2 84 6.1E-7 T 11-10-2018 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SMART SM00382 388 531 3.5E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Gene3D G3DSA:1.10.10.60 630 688 2.3E-17 T 11-10-2018 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SMART SM00091 236 301 2.7E-6 T 11-10-2018 IPR000014 PAS domain UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SMART SM00091 117 183 8.3E-9 T 11-10-2018 IPR000014 PAS domain UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Pfam PF02954 Bacterial regulatory protein, Fis family 642 682 2.7E-15 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Pfam PF00989 PAS fold 237 339 1.7E-13 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Pfam PF00989 PAS fold 120 218 1.3E-12 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Pfam PF00158 Sigma-54 interaction domain 368 535 3.2E-66 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Gene3D G3DSA:1.10.8.60 540 620 1.6E-19 T 11-10-2018 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SUPERFAMILY SSF52540 367 612 5.1E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SUPERFAMILY SSF46689 631 684 4.48E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Gene3D G3DSA:3.40.50.300 355 539 1.1E-63 T 11-10-2018 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SUPERFAMILY SSF55785 217 336 2.97E-14 T 11-10-2018 IPR035965 PAS domain superfamily UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 648 665 3.4E-8 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 665 685 3.4E-8 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Gene3D G3DSA:3.30.450.20 107 219 4.5E-18 T 11-10-2018 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 Gene3D G3DSA:3.30.450.20 223 339 9.3E-17 T 11-10-2018 UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 116 227 2.1E-10 T 11-10-2018 IPR000014 PAS domain UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 233 349 2.3E-16 T 11-10-2018 IPR000014 PAS domain UP12_10915 f3c8e112c14eb37265b51a92b77d05ec 690 SUPERFAMILY SSF51735 1 90 1.98E-14 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17115 bb921683f5ef6e026e5ca39e7ab812d4 89 Gene3D G3DSA:4.10.830.10 30 89 3.3E-26 T 11-10-2018 UP12_17115 bb921683f5ef6e026e5ca39e7ab812d4 89 ProSitePatterns PS00527 Ribosomal protein S14 signature. 51 73 - T 11-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_17115 bb921683f5ef6e026e5ca39e7ab812d4 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 8.5E-29 T 11-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17115 bb921683f5ef6e026e5ca39e7ab812d4 89 SUPERFAMILY SSF57716 2 89 3.49E-33 T 11-10-2018 UP12_17115 bb921683f5ef6e026e5ca39e7ab812d4 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 25.469 T 11-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid UP12_14865 0927ca3cbcda79c93b9cc9af72e2d77b 633 Gene3D G3DSA:1.10.3810.10 64 265 4.8E-71 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_14865 0927ca3cbcda79c93b9cc9af72e2d77b 633 SUPERFAMILY SSF56601 230 632 4.43E-94 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_14865 0927ca3cbcda79c93b9cc9af72e2d77b 633 Gene3D G3DSA:3.40.710.10 300 633 1.7E-93 T 11-10-2018 UP12_14865 0927ca3cbcda79c93b9cc9af72e2d77b 633 Pfam PF00912 Transglycosylase 72 246 4.0E-61 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_14865 0927ca3cbcda79c93b9cc9af72e2d77b 633 SUPERFAMILY SSF53955 61 278 2.81E-72 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_14865 0927ca3cbcda79c93b9cc9af72e2d77b 633 Pfam PF00905 Penicillin binding protein transpeptidase domain 363 603 4.1E-24 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 SUPERFAMILY SSF57716 222 274 3.03E-16 T 11-10-2018 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 Gene3D G3DSA:1.10.8.50 136 275 2.1E-47 T 11-10-2018 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 11-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 44.763 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 SUPERFAMILY SSF81624 2 139 6.28E-44 T 11-10-2018 IPR035937 MutM-like, N-terminal UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 117 2.4E-36 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 134 223 1.9E-31 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 Pfam PF06827 Zinc finger found in FPG and IleRS 246 275 1.3E-9 T 11-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 SMART SM00898 2 118 1.5E-53 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 3.2E-113 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 SMART SM01232 134 226 4.8E-44 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 SUPERFAMILY SSF46946 135 227 1.96E-29 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UP12_13055 a79063172d8ff57bd12a3009a4786e0f 277 Gene3D G3DSA:3.20.190.10 1 135 1.9E-43 T 11-10-2018 IPR035937 MutM-like, N-terminal UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 Gene3D G3DSA:1.10.40.30 409 460 6.3E-21 T 11-10-2018 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 Pfam PF00206 Lyase 14 343 3.1E-114 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 Gene3D G3DSA:1.10.275.10 7 140 1.1E-55 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 SUPERFAMILY SSF48557 6 463 9.27E-149 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 7 469 1.8E-242 T 11-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 ProSitePatterns PS00163 Fumarate lyases signature. 318 327 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 Gene3D G3DSA:1.20.200.10 141 408 1.1E-114 T 11-10-2018 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 1.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 PRINTS PR00149 Fumarate lyase superfamily signature 318 334 1.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 PRINTS PR00149 Fumarate lyase superfamily signature 272 299 1.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 Pfam PF10415 Fumarase C C-terminus 410 462 9.2E-19 T 11-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 PRINTS PR00145 Argininosuccinate lyase family signature 176 196 4.5E-8 T 11-10-2018 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 PRINTS PR00145 Argininosuccinate lyase family signature 135 157 4.5E-8 T 11-10-2018 UP12_18200 6b0dc8b9a388f831385b23a71da1788b 473 PRINTS PR00145 Argininosuccinate lyase family signature 318 334 4.5E-8 T 11-10-2018 UP12_07310 9707bc03c96138a32584e9dcab083dc9 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.124 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07310 9707bc03c96138a32584e9dcab083dc9 57 SUPERFAMILY SSF57829 1 54 7.32E-22 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 UP12_07310 9707bc03c96138a32584e9dcab083dc9 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 3.7E-27 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07310 9707bc03c96138a32584e9dcab083dc9 57 Pfam PF01783 Ribosomal L32p protein family 2 55 1.7E-26 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_05695 69d898c3c68b319d5dbc35a447658869 314 Gene3D G3DSA:1.10.3720.10 84 302 2.5E-21 T 11-10-2018 IPR035906 MetI-like superfamily UP12_05695 69d898c3c68b319d5dbc35a447658869 314 SUPERFAMILY SSF161098 88 294 3.27E-20 T 11-10-2018 IPR035906 MetI-like superfamily UP12_05695 69d898c3c68b319d5dbc35a447658869 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 306 1.1E-41 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_02105 0341eaa9f1f9aa3b00328338e8775ac4 167 SUPERFAMILY SSF55729 5 158 8.62E-17 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_02105 0341eaa9f1f9aa3b00328338e8775ac4 167 Pfam PF00583 Acetyltransferase (GNAT) family 48 139 1.2E-4 T 11-10-2018 IPR000182 GNAT domain UP12_02105 0341eaa9f1f9aa3b00328338e8775ac4 167 Gene3D G3DSA:3.40.630.30 2 160 4.6E-19 T 11-10-2018 UP12_06080 75d5884acdec65f5eddb4fd159a7a6f8 149 SMART SM00871 1 149 2.1E-21 T 11-10-2018 IPR010499 Bacterial transcription activator, effector binding UP12_06080 75d5884acdec65f5eddb4fd159a7a6f8 149 Gene3D G3DSA:3.20.80.10 1 149 1.2E-25 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_06080 75d5884acdec65f5eddb4fd159a7a6f8 149 Pfam PF06445 GyrI-like small molecule binding domain 1 148 4.9E-19 T 11-10-2018 IPR029442 GyrI-like small molecule binding domain UP12_06080 75d5884acdec65f5eddb4fd159a7a6f8 149 SUPERFAMILY SSF55136 1 148 4.19E-20 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_05265 f1d67ee439ac8948841c01718c1dbd34 91 Pfam PF01337 Barstar (barnase inhibitor) 5 84 7.6E-24 T 11-10-2018 IPR000468 Barstar (barnase inhibitor) UP12_05265 f1d67ee439ac8948841c01718c1dbd34 91 SUPERFAMILY SSF52038 1 89 4.58E-29 T 11-10-2018 IPR035905 Barstar-like superfamily UP12_05265 f1d67ee439ac8948841c01718c1dbd34 91 Gene3D G3DSA:3.30.370.10 2 90 8.5E-32 T 11-10-2018 IPR035905 Barstar-like superfamily UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 Pfam PF00929 Exonuclease 7 163 2.9E-33 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 5 925 3.7E-243 T 11-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 Gene3D G3DSA:3.40.50.300 254 504 7.9E-38 T 11-10-2018 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 SMART SM00491 760 892 1.6E-39 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 SMART SM00479 5 172 1.3E-43 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 SUPERFAMILY SSF52540 270 886 7.72E-24 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 Gene3D G3DSA:3.30.420.10 1 172 8.1E-48 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 Pfam PF06733 DEAD_2 415 472 2.7E-5 T 11-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 172 2.6E-29 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 Gene3D G3DSA:3.40.50.300 715 923 6.3E-38 T 11-10-2018 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 SUPERFAMILY SSF53098 5 275 3.8E-53 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 Pfam PF13307 Helicase C-terminal domain 748 904 1.2E-34 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 UP12_10040 41b1739aad3dec7584dfaa7a9387825e 930 Hamap MF_02206 3'-5' exonuclease DinG [dinG]. 2 924 25.777 T 11-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 UP12_16110 194c2d636e91dccc20e0f55dd8d0361f 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 272 1.4E-24 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_16110 194c2d636e91dccc20e0f55dd8d0361f 295 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 45 2.2E-9 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UP12_16110 194c2d636e91dccc20e0f55dd8d0361f 295 Gene3D G3DSA:1.10.3720.10 63 270 5.1E-18 T 11-10-2018 IPR035906 MetI-like superfamily UP12_16110 194c2d636e91dccc20e0f55dd8d0361f 295 SUPERFAMILY SSF161098 68 255 1.1E-21 T 11-10-2018 IPR035906 MetI-like superfamily UP12_03145 21b267d58a5b561a36abd995845fe034 640 SUPERFAMILY SSF52540 4 232 4.79E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03145 21b267d58a5b561a36abd995845fe034 640 Pfam PF16326 ABC transporter C-terminal domain 573 639 4.0E-14 T 11-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 UP12_03145 21b267d58a5b561a36abd995845fe034 640 Pfam PF12848 ABC transporter 231 316 1.5E-25 T 11-10-2018 IPR032781 ABC-transporter extension domain UP12_03145 21b267d58a5b561a36abd995845fe034 640 SMART SM00382 352 517 9.8E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_03145 21b267d58a5b561a36abd995845fe034 640 SMART SM00382 28 232 9.8E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_03145 21b267d58a5b561a36abd995845fe034 640 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_03145 21b267d58a5b561a36abd995845fe034 640 Gene3D G3DSA:3.40.50.300 289 551 2.8E-61 T 11-10-2018 UP12_03145 21b267d58a5b561a36abd995845fe034 640 Gene3D G3DSA:1.10.287.380 552 640 4.7E-7 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 UP12_03145 21b267d58a5b561a36abd995845fe034 640 Gene3D G3DSA:3.40.50.300 1 285 6.6E-68 T 11-10-2018 UP12_03145 21b267d58a5b561a36abd995845fe034 640 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_03145 21b267d58a5b561a36abd995845fe034 640 Pfam PF00005 ABC transporter 19 191 1.9E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_03145 21b267d58a5b561a36abd995845fe034 640 Pfam PF00005 ABC transporter 343 473 3.8E-23 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_03145 21b267d58a5b561a36abd995845fe034 640 SUPERFAMILY SSF52540 310 532 3.37E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02110 84ad5b41e827dc97b36cca7c1768d8c7 264 SMART SM00062 34 257 2.2E-78 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_02110 84ad5b41e827dc97b36cca7c1768d8c7 264 SMART SM00079 34 256 0.0014 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 UP12_02110 84ad5b41e827dc97b36cca7c1768d8c7 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 56 69 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site UP12_02110 84ad5b41e827dc97b36cca7c1768d8c7 264 Gene3D G3DSA:3.40.190.10 116 217 7.0E-64 T 11-10-2018 UP12_02110 84ad5b41e827dc97b36cca7c1768d8c7 264 Gene3D G3DSA:3.40.190.10 40 254 7.0E-64 T 11-10-2018 UP12_02110 84ad5b41e827dc97b36cca7c1768d8c7 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 255 6.5E-62 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_02110 84ad5b41e827dc97b36cca7c1768d8c7 264 SUPERFAMILY SSF53850 4 258 9.47E-68 T 11-10-2018 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 81 94 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 118 131 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 342 353 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 398 411 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 208 221 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 107 115 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 194 207 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 132 147 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 PRINTS PR00415 Aconitase family signature 285 299 3.0E-44 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 ProSitePatterns PS00450 Aconitase family signature 1. 338 354 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 Pfam PF00330 Aconitase family (aconitate hydratase) 7 456 1.3E-155 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 Gene3D G3DSA:3.30.499.10 323 471 4.3E-51 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 SUPERFAMILY SSF53732 1 464 3.4E-165 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 465 59.302 T 11-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 464 8.1E-263 T 11-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 UP12_12405 f331c37fbeac11b0ac46975defeeb677 471 Gene3D G3DSA:3.30.499.20 4 285 8.1E-101 T 11-10-2018 UP12_08110 4f6c2554a151d0a6842f024096446745 157 SUPERFAMILY SSF74942 85 156 1.06E-20 T 11-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily UP12_08110 4f6c2554a151d0a6842f024096446745 157 Pfam PF02576 RimP N-terminal domain 12 84 1.1E-30 T 11-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal UP12_08110 4f6c2554a151d0a6842f024096446745 157 Gene3D G3DSA:3.30.300.70 1 81 4.0E-30 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily UP12_08110 4f6c2554a151d0a6842f024096446745 157 Pfam PF17384 RimP C-terminal SH3 domain 87 156 6.7E-21 T 11-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal UP12_08110 4f6c2554a151d0a6842f024096446745 157 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 156 25.115 T 11-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 UP12_08110 4f6c2554a151d0a6842f024096446745 157 SUPERFAMILY SSF75420 3 84 2.22E-27 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily UP12_08110 4f6c2554a151d0a6842f024096446745 157 Gene3D G3DSA:2.30.30.180 88 154 1.3E-25 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 1.0E-36 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 345 366 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 310 317 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 432 452 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 425 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 3.2E-76 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 Gene3D G3DSA:3.50.50.60 152 273 2.4E-128 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 2.8E-42 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 2.8E-42 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.8E-42 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 317 2.8E-42 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 2.8E-42 T 11-10-2018 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 SUPERFAMILY SSF51905 7 340 2.82E-67 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 PIRSF PIRSF000350 3 457 1.5E-97 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 330 1.0E-73 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 Gene3D G3DSA:3.50.50.60 13 335 2.4E-128 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 468 1.6E-179 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 Gene3D G3DSA:3.30.390.30 348 468 3.8E-42 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 SUPERFAMILY SSF55424 346 468 1.19E-40 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_07075 b97db6d1ad19bd77b5f55c437bffa5b8 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UP12_01705 97105a215c008513f717f0ca6926de40 375 Gene3D G3DSA:3.30.70.360 168 280 1.3E-88 T 11-10-2018 UP12_01705 97105a215c008513f717f0ca6926de40 375 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 358 2.4E-101 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_01705 97105a215c008513f717f0ca6926de40 375 PIRSF PIRSF005962 1 374 1.8E-104 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_01705 97105a215c008513f717f0ca6926de40 375 SUPERFAMILY SSF53187 4 372 4.29E-64 T 11-10-2018 UP12_01705 97105a215c008513f717f0ca6926de40 375 Pfam PF07687 Peptidase dimerisation domain 176 265 5.1E-12 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain UP12_01705 97105a215c008513f717f0ca6926de40 375 SUPERFAMILY SSF55031 173 274 1.5E-22 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_01705 97105a215c008513f717f0ca6926de40 375 Gene3D G3DSA:3.40.630.10 15 355 1.3E-88 T 11-10-2018 UP12_01705 97105a215c008513f717f0ca6926de40 375 Pfam PF01546 Peptidase family M20/M25/M40 69 367 2.7E-25 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_16165 529dd91b899e01bd43398f79f6583e7b 540 SUPERFAMILY SSF52091 433 528 3.34E-19 T 11-10-2018 IPR036513 STAS domain superfamily UP12_16165 529dd91b899e01bd43398f79f6583e7b 540 Pfam PF01740 STAS domain 433 534 1.0E-20 T 11-10-2018 IPR002645 STAS domain UP12_16165 529dd91b899e01bd43398f79f6583e7b 540 Gene3D G3DSA:3.30.750.24 418 536 1.3E-26 T 11-10-2018 IPR036513 STAS domain superfamily UP12_16165 529dd91b899e01bd43398f79f6583e7b 540 Pfam PF00916 Sulfate permease family 15 379 2.7E-96 T 11-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UP12_10555 0541b328f4e6f61f3a68b113a3c91660 146 SUPERFAMILY SSF55874 28 135 4.85E-24 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_10555 0541b328f4e6f61f3a68b113a3c91660 146 Gene3D G3DSA:3.30.565.10 1 143 9.0E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_10555 0541b328f4e6f61f3a68b113a3c91660 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 35.657 T 11-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 UP12_10555 0541b328f4e6f61f3a68b113a3c91660 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 137 1.9E-73 T 11-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 UP12_10555 0541b328f4e6f61f3a68b113a3c91660 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 3.2E-23 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_10555 0541b328f4e6f61f3a68b113a3c91660 146 SMART SM00387 35 140 5.5E-9 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_14100 7f6c2b5068ee94cf06eb0b974aa207bb 402 SUPERFAMILY SSF56796 13 395 3.4E-120 T 11-10-2018 UP12_14100 7f6c2b5068ee94cf06eb0b974aa207bb 402 Gene3D G3DSA:3.40.50.1970 3 197 2.0E-59 T 11-10-2018 UP12_14100 7f6c2b5068ee94cf06eb0b974aa207bb 402 Pfam PF00465 Iron-containing alcohol dehydrogenase 19 385 1.6E-118 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 UP12_14100 7f6c2b5068ee94cf06eb0b974aa207bb 402 Gene3D G3DSA:1.20.1090.10 199 397 2.8E-60 T 11-10-2018 UP12_14100 7f6c2b5068ee94cf06eb0b974aa207bb 402 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 273 293 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 UP12_14100 7f6c2b5068ee94cf06eb0b974aa207bb 402 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 186 214 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 Gene3D G3DSA:1.10.540.10 1 144 3.3E-43 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 SUPERFAMILY SSF47203 249 421 2.09E-40 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 SUPERFAMILY SSF56645 20 262 1.96E-72 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 238 2.8E-22 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 142 4.0E-28 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 148 160 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 414 6.9E-34 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 Gene3D G3DSA:2.40.110.10 145 250 1.6E-35 T 11-10-2018 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 Gene3D G3DSA:1.20.140.10 251 421 1.1E-50 T 11-10-2018 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 377 396 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_15450 e1fc31075cff4b247ad55a8a4851cff6 593 Gene3D G3DSA:1.20.140.10 422 593 1.2E-54 T 11-10-2018 UP12_18035 7ba7fac1283860e1a22cdda5bb5b07ed 177 Pfam PF04542 Sigma-70 region 2 24 91 1.9E-14 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_18035 7ba7fac1283860e1a22cdda5bb5b07ed 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 174 4.2E-29 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_18035 7ba7fac1283860e1a22cdda5bb5b07ed 177 SUPERFAMILY SSF88946 2 96 2.62E-27 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_18035 7ba7fac1283860e1a22cdda5bb5b07ed 177 Pfam PF08281 Sigma-70, region 4 120 171 9.2E-17 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_18035 7ba7fac1283860e1a22cdda5bb5b07ed 177 Gene3D G3DSA:1.10.1740.10 1 113 1.6E-27 T 11-10-2018 UP12_18035 7ba7fac1283860e1a22cdda5bb5b07ed 177 SUPERFAMILY SSF88659 115 175 1.07E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_18035 7ba7fac1283860e1a22cdda5bb5b07ed 177 Gene3D G3DSA:1.10.10.10 114 177 1.3E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09550 c3de69fb16953987020824c67876c761 441 Gene3D G3DSA:3.90.1720.10 317 441 4.4E-31 T 11-10-2018 UP12_09550 c3de69fb16953987020824c67876c761 441 Pfam PF01476 LysM domain 250 291 6.5E-16 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 Pfam PF01476 LysM domain 30 71 4.3E-15 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 Pfam PF01476 LysM domain 97 138 2.3E-13 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 Pfam PF01476 LysM domain 174 215 3.0E-13 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 SUPERFAMILY SSF54001 320 440 7.85E-32 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_09550 c3de69fb16953987020824c67876c761 441 SUPERFAMILY SSF54106 96 138 1.7E-10 T 11-10-2018 UP12_09550 c3de69fb16953987020824c67876c761 441 SUPERFAMILY SSF54106 172 215 6.28E-10 T 11-10-2018 UP12_09550 c3de69fb16953987020824c67876c761 441 SUPERFAMILY SSF54106 27 71 8.63E-11 T 11-10-2018 UP12_09550 c3de69fb16953987020824c67876c761 441 SUPERFAMILY SSF54106 248 291 1.57E-11 T 11-10-2018 UP12_09550 c3de69fb16953987020824c67876c761 441 SMART SM00257 173 216 1.3E-15 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 SMART SM00257 96 139 1.2E-15 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 SMART SM00257 28 71 1.8E-17 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 SMART SM00257 249 292 4.8E-16 T 11-10-2018 IPR018392 LysM domain UP12_09550 c3de69fb16953987020824c67876c761 441 Pfam PF00877 NlpC/P60 family 338 438 4.1E-27 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_09550 c3de69fb16953987020824c67876c761 441 Gene3D G3DSA:3.10.350.10 25 79 3.4E-17 T 11-10-2018 IPR036779 LysM domain superfamily UP12_09550 c3de69fb16953987020824c67876c761 441 Gene3D G3DSA:3.10.350.10 92 145 2.4E-18 T 11-10-2018 IPR036779 LysM domain superfamily UP12_09550 c3de69fb16953987020824c67876c761 441 Gene3D G3DSA:3.10.350.10 245 297 1.7E-18 T 11-10-2018 IPR036779 LysM domain superfamily UP12_09550 c3de69fb16953987020824c67876c761 441 Gene3D G3DSA:3.10.350.10 169 222 8.6E-16 T 11-10-2018 IPR036779 LysM domain superfamily UP12_11445 a00ab0320508be7ac36dfe11142d80e3 273 Pfam PF03618 Kinase/pyrophosphorylase 6 263 1.8E-97 T 11-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 UP12_11445 a00ab0320508be7ac36dfe11142d80e3 273 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 4 269 60.898 T 11-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 Gene3D G3DSA:3.30.360.10 131 236 5.4E-78 T 11-10-2018 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 151 168 - T 11-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 129 3.0E-32 T 11-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 5 267 2.3E-92 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 SUPERFAMILY SSF51735 4 156 5.42E-37 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 SUPERFAMILY SSF55347 130 238 1.31E-38 T 11-10-2018 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 132 265 3.7E-32 T 11-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 6 267 30.307 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 Gene3D G3DSA:3.40.50.720 7 264 5.4E-78 T 11-10-2018 UP12_10085 9b13a3f8a1114b2375dce6700a313b60 267 PIRSF PIRSF000161 4 267 1.3E-72 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Hamap MF_01113 DNA polymerase IV [dinB]. 3 360 32.177 T 11-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Pfam PF11799 impB/mucB/samB family C-terminal domain 246 355 5.6E-19 T 11-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Gene3D G3DSA:3.30.1490.100 248 357 4.2E-19 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Pfam PF11798 IMS family HHH motif 173 203 1.0E-6 T 11-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Gene3D G3DSA:3.30.70.270 6 163 2.3E-46 T 11-10-2018 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Pfam PF00817 impB/mucB/samB family 9 157 2.4E-43 T 11-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Gene3D G3DSA:2.30.40.20 23 76 2.3E-46 T 11-10-2018 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 SUPERFAMILY SSF100879 247 348 8.24E-20 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 Gene3D G3DSA:1.10.150.20 173 232 2.7E-13 T 11-10-2018 UP12_10685 d8ba4e32e946196808cc5b41b4ff1cd7 410 SUPERFAMILY SSF56672 4 240 7.12E-72 T 11-10-2018 UP12_10610 48e3ecfc5288f7e46396308b3b6c8f35 150 Pfam PF13673 Acetyltransferase (GNAT) domain 28 148 2.3E-20 T 11-10-2018 IPR000182 GNAT domain UP12_10610 48e3ecfc5288f7e46396308b3b6c8f35 150 SUPERFAMILY SSF55729 5 148 2.57E-31 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_10610 48e3ecfc5288f7e46396308b3b6c8f35 150 Gene3D G3DSA:3.40.630.30 2 148 1.8E-40 T 11-10-2018 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 SUPERFAMILY SSF52402 22 248 2.65E-53 T 11-10-2018 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 Pfam PF11734 TilS substrate C-terminal domain 401 458 9.8E-16 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 Gene3D G3DSA:1.20.59.30 258 344 1.1E-26 T 11-10-2018 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 SMART SM00977 400 473 2.8E-27 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 Gene3D G3DSA:1.10.10.1360 138 222 5.9E-67 T 11-10-2018 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 SUPERFAMILY SSF56037 360 458 1.54E-19 T 11-10-2018 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 SUPERFAMILY SSF82829 227 337 8.63E-11 T 11-10-2018 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 Gene3D G3DSA:3.40.50.620 32 176 5.9E-67 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 34 220 8.6E-59 T 11-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 18 332 23.458 T 11-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 400 446 2.8E-22 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 UP12_00410 bc2be7a624aaa325608c0f8d63cbe4f3 481 Pfam PF01171 PP-loop family 34 216 1.9E-57 T 11-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 Gene3D G3DSA:3.20.20.300 27 416 4.3E-160 T 11-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 SUPERFAMILY SSF52279 432 632 2.48E-13 T 11-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 41 388 1.7E-116 T 11-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 Gene3D G3DSA:3.40.50.1700 417 636 9.0E-62 T 11-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 SUPERFAMILY SSF51445 23 431 3.37E-102 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 432 632 3.0E-20 T 11-10-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 301 318 - T 11-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 PRINTS PR00133 Glycosyl hydrolase family 3 signature 135 154 5.2E-5 T 11-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 PRINTS PR00133 Glycosyl hydrolase family 3 signature 213 229 5.2E-5 T 11-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UP12_01000 43fb9f5d5760883f93b6d028016b1447 639 PRINTS PR00133 Glycosyl hydrolase family 3 signature 301 319 5.2E-5 T 11-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 SMART SM00363 92 156 5.0E-18 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 Pfam PF01479 S4 domain 93 139 2.1E-20 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 5.1E-84 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 11-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 7.0E-29 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 Gene3D G3DSA:1.10.1050.10 6 200 1.3E-75 T 11-10-2018 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 SUPERFAMILY SSF55174 2 200 1.2E-66 T 11-10-2018 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 SMART SM01390 3 91 9.3E-47 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 36.321 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 UP12_13360 41c490ed8298557e220cd8b137eb0702 200 Gene3D G3DSA:3.10.290.10 91 185 1.3E-75 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 Gene3D G3DSA:3.40.50.1170 1 199 1.2E-70 T 11-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 PIRSF PIRSF001220 1 327 1.8E-98 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 PIRSF PIRSF500176 1 325 1.6E-104 T 11-10-2018 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 Pfam PF00710 Asparaginase, N-terminal 3 187 1.4E-65 T 11-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 SMART SM00870 3 316 9.2E-119 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 11-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 Gene3D G3DSA:3.40.50.40 200 328 1.0E-35 T 11-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 1 328 3.4E-133 T 11-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 11-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 PRINTS PR00139 Asparaginase/glutaminase family signature 253 271 2.1E-15 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 2.1E-15 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 2.1E-15 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 UP12_18205 16f62663891bb8c7441b1718532acf6d 329 SUPERFAMILY SSF53774 2 328 1.13E-98 T 11-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 SUPERFAMILY SSF52540 138 434 4.39E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10260 060ebc5a6a0c474394efe554ac510512 436 SUPERFAMILY SSF52540 5 167 1.8E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10260 060ebc5a6a0c474394efe554ac510512 436 PIRSF PIRSF006485 2 436 6.1E-174 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 3.6E-178 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 Gene3D G3DSA:3.40.50.300 1 163 1.6E-47 T 11-10-2018 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 1.8E-25 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 6.7E-26 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 179 324 2.8E-24 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 151 1.2E-23 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 Gene3D G3DSA:3.40.50.300 170 352 2.7E-56 T 11-10-2018 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 Gene3D G3DSA:3.30.300.20 353 436 1.4E-36 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_10260 060ebc5a6a0c474394efe554ac510512 436 Hamap MF_00195 GTPase Der [der]. 3 436 41.009 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 UP12_10260 060ebc5a6a0c474394efe554ac510512 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 5.9E-35 T 11-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 11-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 Pfam PF02132 RecR protein 40 78 1.3E-17 T 11-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 SUPERFAMILY SSF111304 1 198 1.83E-79 T 11-10-2018 IPR023627 Recombination protein RecR UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 Gene3D G3DSA:1.10.8.420 1 53 3.9E-20 T 11-10-2018 UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 TIGRFAM TIGR00615 recR: recombination protein RecR 1 196 1.3E-91 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 112.154 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 SMART SM00493 80 165 1.5E-19 T 11-10-2018 IPR006171 TOPRIM domain UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 Gene3D G3DSA:3.40.1360.10 77 198 6.7E-50 T 11-10-2018 UP12_00145 cae0eec3a593ce858ac6141e299e79cd 198 Pfam PF13662 Toprim domain 80 171 2.7E-26 T 11-10-2018 IPR006171 TOPRIM domain UP12_11475 66902ec6357201a48cdc65c9dae30f1c 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 130 1.4E-45 T 11-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 UP12_11475 66902ec6357201a48cdc65c9dae30f1c 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UP12_11475 66902ec6357201a48cdc65c9dae30f1c 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 2.7E-16 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain UP12_11475 66902ec6357201a48cdc65c9dae30f1c 132 Gene3D G3DSA:3.40.140.10 1 132 1.4E-57 T 11-10-2018 UP12_11475 66902ec6357201a48cdc65c9dae30f1c 132 SUPERFAMILY SSF53927 2 130 4.67E-48 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_04020 a6e2bb7961103a76730ef26830c64333 355 Pfam PF01699 Sodium/calcium exchanger protein 210 350 3.9E-19 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 UP12_04020 a6e2bb7961103a76730ef26830c64333 355 Pfam PF01699 Sodium/calcium exchanger protein 27 178 6.8E-21 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 UP12_04020 a6e2bb7961103a76730ef26830c64333 355 TIGRFAM TIGR00378 cax: calcium/proton exchanger 11 353 1.5E-147 T 11-10-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 UP12_04020 a6e2bb7961103a76730ef26830c64333 355 Gene3D G3DSA:1.20.58.1130 39 242 1.4E-24 T 11-10-2018 UP12_04020 a6e2bb7961103a76730ef26830c64333 355 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 5 353 3.0E-120 T 11-10-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 UP12_04020 a6e2bb7961103a76730ef26830c64333 355 Gene3D G3DSA:1.20.1420.30 57 345 1.4E-24 T 11-10-2018 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SMART SM00483 1 314 5.2E-88 T 11-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Pfam PF02811 PHP domain 337 454 8.5E-7 T 11-10-2018 IPR004013 PHP domain GO:0003824 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Pfam PF14716 Helix-hairpin-helix domain 4 69 2.9E-18 T 11-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 PIRSF PIRSF005047 1 570 7.4E-240 T 11-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Pfam PF14520 Helix-hairpin-helix domain 90 144 2.5E-7 T 11-10-2018 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SUPERFAMILY SSF81301 152 314 2.88E-41 T 11-10-2018 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SUPERFAMILY SSF89550 334 569 2.88E-54 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Gene3D G3DSA:3.30.460.10 152 258 3.9E-23 T 11-10-2018 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SUPERFAMILY SSF47802 2 81 1.96E-20 T 11-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Gene3D G3DSA:3.30.210.10 259 323 2.8E-14 T 11-10-2018 IPR037160 DNA polymerase, thumb domain superfamily UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SMART SM00278 123 142 2.1 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SMART SM00278 48 67 4.8 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SMART SM00278 88 107 71.0 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Pfam PF14791 DNA polymerase beta thumb 253 314 1.1E-15 T 11-10-2018 IPR029398 DNA polymerase beta, thumb domain UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 SMART SM00481 336 415 1.1E-22 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Gene3D G3DSA:3.20.20.140 324 570 2.9E-76 T 11-10-2018 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Gene3D G3DSA:1.10.150.20 83 148 1.2E-19 T 11-10-2018 UP12_12895 c0a19ededfd8e8ff823556e7d9b1dcaf 570 Gene3D G3DSA:1.10.150.110 1 82 1.0E-19 T 11-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 SUPERFAMILY SSF54736 50 121 7.15E-25 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 Gene3D G3DSA:3.30.1390.10 51 121 7.6E-31 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 25.514 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 50 1.3E-19 T 11-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 94 9.0E-15 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 SUPERFAMILY SSF48300 4 56 1.96E-14 T 11-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 Gene3D G3DSA:1.20.5.710 2 50 4.7E-20 T 11-10-2018 UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 2.2E-30 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00670 3dae922916e1e99b68fc2b1ad5321ef0 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 1.3E-50 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_16860 6cb7fcf048a42d51a298b545e287675e 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 20 37 3.8E-49 T 11-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 UP12_16860 6cb7fcf048a42d51a298b545e287675e 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 118 132 3.8E-49 T 11-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 UP12_16860 6cb7fcf048a42d51a298b545e287675e 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 66 80 3.8E-49 T 11-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 UP12_16860 6cb7fcf048a42d51a298b545e287675e 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 88 101 3.8E-49 T 11-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 UP12_16860 6cb7fcf048a42d51a298b545e287675e 149 PRINTS PR01759 Capsule biosynthesis protein CapC signature 2 17 3.8E-49 T 11-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 UP12_16860 6cb7fcf048a42d51a298b545e287675e 149 Pfam PF14102 Capsule biosynthesis CapC 12 128 1.1E-40 T 11-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 UP12_16860 6cb7fcf048a42d51a298b545e287675e 149 TIGRFAM TIGR04011 poly_gGlu_PgsC: poly-gamma-glutamate biosynthesis protein PgsC 10 139 1.6E-45 T 11-10-2018 IPR008338 Capsule biosynthesis protein CapC GO:0016020|GO:0045227 UP12_08500 7850499bc179301bd0b71023c691babc 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 11-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UP12_08500 7850499bc179301bd0b71023c691babc 444 SUPERFAMILY SSF55931 105 442 3.34E-130 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UP12_08500 7850499bc179301bd0b71023c691babc 444 Gene3D G3DSA:3.30.590.10 108 444 2.2E-149 T 11-10-2018 UP12_08500 7850499bc179301bd0b71023c691babc 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 11-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UP12_08500 7850499bc179301bd0b71023c691babc 444 SMART SM01230 105 354 2.2E-140 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UP12_08500 7850499bc179301bd0b71023c691babc 444 Gene3D G3DSA:3.10.20.70 2 107 2.6E-46 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UP12_08500 7850499bc179301bd0b71023c691babc 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 1.3E-190 T 11-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UP12_08500 7850499bc179301bd0b71023c691babc 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 1.3E-141 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UP12_08500 7850499bc179301bd0b71023c691babc 444 SUPERFAMILY SSF54368 5 104 1.44E-35 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 UP12_08500 7850499bc179301bd0b71023c691babc 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 11-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UP12_08500 7850499bc179301bd0b71023c691babc 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 99 1.4E-33 T 11-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 UP12_18470 e3ff877a9fd96939557a222cbe397b67 285 Gene3D G3DSA:3.40.50.10490 99 284 2.8E-55 T 11-10-2018 UP12_18470 e3ff877a9fd96939557a222cbe397b67 285 Pfam PF01380 SIS domain 131 259 3.7E-26 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_18470 e3ff877a9fd96939557a222cbe397b67 285 SUPERFAMILY SSF53697 95 284 2.23E-49 T 11-10-2018 UP12_18470 e3ff877a9fd96939557a222cbe397b67 285 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 81 8.8E-20 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_18470 e3ff877a9fd96939557a222cbe397b67 285 SUPERFAMILY SSF46689 7 81 3.23E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_18470 e3ff877a9fd96939557a222cbe397b67 285 Gene3D G3DSA:1.10.10.10 3 84 3.4E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_17925 b886224ea9eeb8414bad68ab35a5aac8 242 PIRSF PIRSF039085 1 242 6.7E-119 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UP12_17925 b886224ea9eeb8414bad68ab35a5aac8 242 Pfam PF00005 ABC transporter 19 167 6.8E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17925 b886224ea9eeb8414bad68ab35a5aac8 242 SMART SM00382 28 223 4.1E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17925 b886224ea9eeb8414bad68ab35a5aac8 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_17925 b886224ea9eeb8414bad68ab35a5aac8 242 SUPERFAMILY SSF52540 3 237 2.47E-81 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17925 b886224ea9eeb8414bad68ab35a5aac8 242 Gene3D G3DSA:3.40.50.300 1 242 1.7E-81 T 11-10-2018 UP12_07995 4b5986feea1dbe3b2b17172dcc98783f 371 Gene3D G3DSA:1.20.120.1380 129 362 3.9E-79 T 11-10-2018 UP12_07995 4b5986feea1dbe3b2b17172dcc98783f 371 Pfam PF00448 SRP54-type protein, GTPase domain 181 370 7.2E-45 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07995 4b5986feea1dbe3b2b17172dcc98783f 371 Gene3D G3DSA:3.40.50.300 175 359 3.9E-79 T 11-10-2018 UP12_07995 4b5986feea1dbe3b2b17172dcc98783f 371 SMART SM00962 180 371 2.1E-55 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07995 4b5986feea1dbe3b2b17172dcc98783f 371 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 267 5.5E-59 T 11-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 UP12_07995 4b5986feea1dbe3b2b17172dcc98783f 371 SUPERFAMILY SSF52540 180 358 2.89E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 SUPERFAMILY SSF58104 228 559 5.89E-68 T 11-10-2018 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 Pfam PF00672 HAMP domain 204 253 5.0E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 SMART SM00283 285 560 8.2E-67 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 Gene3D G3DSA:1.20.1480.50 162 257 4.4E-13 T 11-10-2018 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 SMART SM00304 203 256 2.0E-11 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 412 441 5.1E-19 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 17 5.1E-19 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 410 5.1E-19 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 Gene3D G3DSA:1.10.287.950 258 560 5.6E-64 T 11-10-2018 UP12_16510 473c696b9627364dfb67aa0ddf2946a2 561 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 335 509 3.2E-44 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_00605 10e0ae649a650101a67e6f905d2af2dd 158 Pfam PF02542 YgbB family 3 156 1.1E-65 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UP12_00605 10e0ae649a650101a67e6f905d2af2dd 158 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 11-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UP12_00605 10e0ae649a650101a67e6f905d2af2dd 158 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 2.2E-71 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UP12_00605 10e0ae649a650101a67e6f905d2af2dd 158 SUPERFAMILY SSF69765 1 157 1.96E-66 T 11-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UP12_00605 10e0ae649a650101a67e6f905d2af2dd 158 Gene3D G3DSA:3.30.1330.50 1 158 4.5E-68 T 11-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UP12_00605 10e0ae649a650101a67e6f905d2af2dd 158 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 36.441 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 Gene3D G3DSA:3.50.30.10 6 234 3.8E-80 T 11-10-2018 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 540 1.2E-128 T 11-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 11-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 PIRSF PIRSF000732 1 572 1.5E-227 T 11-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 SUPERFAMILY SSF47831 23 143 1.96E-37 T 11-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 1.2E-32 T 11-10-2018 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 1.2E-32 T 11-10-2018 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 1.2E-32 T 11-10-2018 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 1.2E-32 T 11-10-2018 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 11-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 4 566 4.6E-266 T 11-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 Gene3D G3DSA:3.20.20.60 235 569 1.7E-126 T 11-10-2018 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 Gene3D G3DSA:1.10.274.10 23 146 3.8E-80 T 11-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 225 2.9E-25 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 SUPERFAMILY SSF51621 249 546 2.62E-112 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 SUPERFAMILY SSF52009 125 246 1.44E-37 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 UP12_06710 9c5c00155d8b354a6aa1b959a9c2f934 572 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 126 4.7E-34 T 11-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 UP12_13920 30bd7256e42055c653c188fd5152fa06 312 PIRSF PIRSF005355 13 310 1.5E-88 T 11-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 UP12_13920 30bd7256e42055c653c188fd5152fa06 312 Pfam PF01040 UbiA prenyltransferase family 35 265 2.4E-38 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 UP12_13920 30bd7256e42055c653c188fd5152fa06 312 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 18 305 19.947 T 11-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UP12_13920 30bd7256e42055c653c188fd5152fa06 312 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 27 297 4.1E-34 T 11-10-2018 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 SUPERFAMILY SSF53822 60 323 1.39E-66 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 SMART SM00354 1 71 2.5E-35 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 Gene3D G3DSA:3.40.50.2300 155 282 7.2E-71 T 11-10-2018 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 SUPERFAMILY SSF47413 2 59 7.31E-18 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 Pfam PF13377 Periplasmic binding protein-like domain 165 322 8.7E-31 T 11-10-2018 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.6E-21 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 11-10-2018 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 Gene3D G3DSA:3.40.50.2300 62 302 7.2E-71 T 11-10-2018 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 6.3E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 6.3E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_16885 7f5c0eb907335da513035d6e51d7b325 328 Gene3D G3DSA:1.10.260.40 3 58 4.8E-24 T 11-10-2018 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 Gene3D G3DSA:1.10.340.30 30 141 7.1E-89 T 11-10-2018 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 Gene3D G3DSA:3.90.79.10 241 363 2.2E-26 T 11-10-2018 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 SUPERFAMILY SSF48150 15 231 2.04E-72 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 Gene3D G3DSA:1.10.1670.10 19 222 7.1E-89 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 SUPERFAMILY SSF55811 229 361 1.97E-24 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 44 173 1.0E-20 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 16 277 3.1E-112 T 11-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 Pfam PF14815 NUDIX domain 244 357 3.3E-22 T 11-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 SMART SM00478 48 199 1.2E-52 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 201 217 - T 11-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 UP12_04360 4d0c3edac6c8ca33bcbac0ba947f091c 366 Pfam PF00633 Helix-hairpin-helix motif 108 137 8.1E-7 T 11-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 UP12_00215 5a46dd4a71cd8be8fa234abca6b3c024 146 SUPERFAMILY SSF158397 27 146 5.1E-33 T 11-10-2018 IPR024042 TM1646-like domain superfamily UP12_00215 5a46dd4a71cd8be8fa234abca6b3c024 146 Gene3D G3DSA:1.20.120.490 25 146 6.4E-36 T 11-10-2018 IPR024042 TM1646-like domain superfamily UP12_00215 5a46dd4a71cd8be8fa234abca6b3c024 146 Pfam PF03885 Protein of unknown function (DUF327) 22 145 1.5E-36 T 11-10-2018 IPR005585 Protein of unknown function DUF327 UP12_17825 b3f08a990508afd10a9fc85278e7690b 508 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 23 235 8.2E-32 T 11-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UP12_17825 b3f08a990508afd10a9fc85278e7690b 508 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 251 437 1.3E-35 T 11-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 UP12_17825 b3f08a990508afd10a9fc85278e7690b 508 PIRSF PIRSF006005 3 507 2.0E-218 T 11-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17825 b3f08a990508afd10a9fc85278e7690b 508 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 508 256.012 T 11-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17825 b3f08a990508afd10a9fc85278e7690b 508 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 263 280 - T 11-10-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_17825 b3f08a990508afd10a9fc85278e7690b 508 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 9 504 3.0E-217 T 11-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 UP12_10180 7df82d7de017d7214670763526f25a96 515 SUPERFAMILY SSF56322 18 497 3.66E-147 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_10180 7df82d7de017d7214670763526f25a96 515 Pfam PF00425 chorismate binding enzyme 231 484 1.8E-96 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal UP12_10180 7df82d7de017d7214670763526f25a96 515 Gene3D G3DSA:3.60.120.10 1 502 2.2E-166 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_10180 7df82d7de017d7214670763526f25a96 515 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 29 493 5.1E-180 T 11-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_10180 7df82d7de017d7214670763526f25a96 515 PRINTS PR00095 Anthranilate synthase component I signature 332 345 1.1E-20 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_10180 7df82d7de017d7214670763526f25a96 515 PRINTS PR00095 Anthranilate synthase component I signature 441 455 1.1E-20 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_10180 7df82d7de017d7214670763526f25a96 515 PRINTS PR00095 Anthranilate synthase component I signature 426 440 1.1E-20 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_10180 7df82d7de017d7214670763526f25a96 515 PRINTS PR00095 Anthranilate synthase component I signature 346 359 1.1E-20 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_10180 7df82d7de017d7214670763526f25a96 515 Pfam PF04715 Anthranilate synthase component I, N terminal region 29 167 2.1E-28 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_12095 ce4f8ec1db45eb23acf0de2ca03516c6 117 Pfam PF06305 Lipopolysaccharide assembly protein A domain 25 80 4.6E-14 T 11-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 UP12_01180 dc23a20dc290cf335c3d81c9917a5d09 291 SUPERFAMILY SSF52540 3 222 5.73E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_01180 dc23a20dc290cf335c3d81c9917a5d09 291 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_01180 dc23a20dc290cf335c3d81c9917a5d09 291 Pfam PF00005 ABC transporter 20 158 2.0E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_01180 dc23a20dc290cf335c3d81c9917a5d09 291 Gene3D G3DSA:3.40.50.300 2 258 2.9E-50 T 11-10-2018 UP12_01180 dc23a20dc290cf335c3d81c9917a5d09 291 SMART SM00382 28 207 1.3E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_12815 1c5167292245532c88c6cc0c68d90851 254 SUPERFAMILY SSF46548 114 239 2.27E-26 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_12815 1c5167292245532c88c6cc0c68d90851 254 SUPERFAMILY SSF54292 6 112 1.48E-21 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 UP12_12815 1c5167292245532c88c6cc0c68d90851 254 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 234 3.1E-40 T 11-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12815 1c5167292245532c88c6cc0c68d90851 254 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 155 166 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UP12_12815 1c5167292245532c88c6cc0c68d90851 254 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 118 1.2E-28 T 11-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12815 1c5167292245532c88c6cc0c68d90851 254 Pfam PF13183 4Fe-4S dicluster domain 151 226 9.7E-9 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UP12_12815 1c5167292245532c88c6cc0c68d90851 254 Gene3D G3DSA:3.10.20.30 1 112 1.1E-30 T 11-10-2018 IPR012675 Beta-grasp domain superfamily UP12_12815 1c5167292245532c88c6cc0c68d90851 254 Gene3D G3DSA:1.10.1060.10 114 248 5.4E-28 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_10380 0e955ea9b750fa231971b99ad786602f 214 Pfam PF01476 LysM domain 170 211 9.1E-11 T 11-10-2018 IPR018392 LysM domain UP12_10380 0e955ea9b750fa231971b99ad786602f 214 Gene3D G3DSA:3.10.350.10 165 214 2.9E-15 T 11-10-2018 IPR036779 LysM domain superfamily UP12_10380 0e955ea9b750fa231971b99ad786602f 214 SMART SM00257 169 212 3.5E-11 T 11-10-2018 IPR018392 LysM domain UP12_10380 0e955ea9b750fa231971b99ad786602f 214 Pfam PF01551 Peptidase family M23 46 146 4.0E-31 T 11-10-2018 IPR016047 Peptidase M23 UP12_10380 0e955ea9b750fa231971b99ad786602f 214 Gene3D G3DSA:2.70.70.10 18 162 1.6E-39 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_10380 0e955ea9b750fa231971b99ad786602f 214 SUPERFAMILY SSF54106 169 211 1.12E-10 T 11-10-2018 UP12_10380 0e955ea9b750fa231971b99ad786602f 214 SUPERFAMILY SSF51261 25 149 1.31E-42 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_18730 0d545ab92050aa9b384f9f3364378821 298 Gene3D G3DSA:3.10.310.10 128 287 1.1E-86 T 11-10-2018 UP12_18730 0d545ab92050aa9b384f9f3364378821 298 PIRSF PIRSF016184 1 298 1.1E-83 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UP12_18730 0d545ab92050aa9b384f9f3364378821 298 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 297 1.8E-79 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UP12_18730 0d545ab92050aa9b384f9f3364378821 298 Pfam PF02567 Phenazine biosynthesis-like protein 9 294 2.2E-74 T 11-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 UP12_18730 0d545ab92050aa9b384f9f3364378821 298 Gene3D G3DSA:3.10.310.10 7 289 1.1E-86 T 11-10-2018 UP12_18730 0d545ab92050aa9b384f9f3364378821 298 SUPERFAMILY SSF54506 4 298 7.46E-67 T 11-10-2018 UP12_10105 5007f91a5dd2ba5711dba5c820a207c9 197 Pfam PF07187 Protein of unknown function (DUF1405) 24 181 3.9E-58 T 11-10-2018 IPR009845 Protein of unknown function DUF1405 UP12_07065 45a85f5c31e56375d9dd317ca1d91abc 325 Gene3D G3DSA:3.40.50.970 1 192 4.7E-80 T 11-10-2018 UP12_07065 45a85f5c31e56375d9dd317ca1d91abc 325 Gene3D G3DSA:3.40.50.920 193 325 2.2E-47 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_07065 45a85f5c31e56375d9dd317ca1d91abc 325 SUPERFAMILY SSF52922 188 325 3.01E-41 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_07065 45a85f5c31e56375d9dd317ca1d91abc 325 SMART SM00861 4 179 4.8E-63 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_07065 45a85f5c31e56375d9dd317ca1d91abc 325 SUPERFAMILY SSF52518 2 204 3.24E-66 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_07065 45a85f5c31e56375d9dd317ca1d91abc 325 Pfam PF02780 Transketolase, C-terminal domain 194 314 5.6E-39 T 11-10-2018 IPR033248 Transketolase, C-terminal domain UP12_07065 45a85f5c31e56375d9dd317ca1d91abc 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 4.6E-40 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_16155 c5fec964cb9e19df774e372047ac6be6 192 Gene3D G3DSA:3.40.50.450 1 191 1.8E-76 T 11-10-2018 UP12_16155 c5fec964cb9e19df774e372047ac6be6 192 Pfam PF03641 Possible lysine decarboxylase 46 176 2.3E-42 T 11-10-2018 IPR031100 LOG family UP12_16155 c5fec964cb9e19df774e372047ac6be6 192 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 179 1.3E-73 T 11-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG UP12_16155 c5fec964cb9e19df774e372047ac6be6 192 SUPERFAMILY SSF102405 1 179 6.56E-59 T 11-10-2018 UP12_15035 a982b5b672c2dbc08aa02a6c44334eb1 177 Pfam PF01966 HD domain 26 138 8.2E-14 T 11-10-2018 IPR006674 HD domain UP12_15035 a982b5b672c2dbc08aa02a6c44334eb1 177 Gene3D G3DSA:1.10.3210.10 7 170 2.3E-16 T 11-10-2018 UP12_15035 a982b5b672c2dbc08aa02a6c44334eb1 177 TIGRFAM TIGR00277 HDIG: HDIG domain 25 92 1.9E-8 T 11-10-2018 IPR006675 HDIG domain UP12_15035 a982b5b672c2dbc08aa02a6c44334eb1 177 SMART SM00471 19 149 9.3E-9 T 11-10-2018 IPR003607 HD/PDEase domain UP12_15035 a982b5b672c2dbc08aa02a6c44334eb1 177 SUPERFAMILY SSF109604 16 138 2.16E-20 T 11-10-2018 UP12_17335 6858a3fb0e0e355cbab2754502b20b7d 176 SUPERFAMILY SSF53697 19 163 2.05E-7 T 11-10-2018 UP12_17335 6858a3fb0e0e355cbab2754502b20b7d 176 Gene3D G3DSA:3.40.50.10490 1 176 4.3E-57 T 11-10-2018 UP12_17335 6858a3fb0e0e355cbab2754502b20b7d 176 Pfam PF10740 Domain of unknown function (DUF2529) 2 172 2.0E-62 T 11-10-2018 IPR019676 Domain of unknown function (DUF2529) UP12_10635 a9ccb3865ae21c8a9e63703279c9230b 186 SUPERFAMILY SSF52218 1 158 7.45E-39 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_10635 a9ccb3865ae21c8a9e63703279c9230b 186 Pfam PF02525 Flavodoxin-like fold 1 155 1.8E-37 T 11-10-2018 IPR003680 Flavodoxin-like fold UP12_10635 a9ccb3865ae21c8a9e63703279c9230b 186 Gene3D G3DSA:3.40.50.360 1 186 3.2E-52 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_11585 96ec884a9e7b42333f36690531aabc20 110 ProDom PD072942 YQXA ORF79 1 107 4.0E-30 T 11-10-2018 IPR020534 Uncharacterised protein family YqxA UP12_11585 96ec884a9e7b42333f36690531aabc20 110 Pfam PF12438 Protein of unknown function (DUF3679) 7 62 1.7E-26 T 11-10-2018 IPR020534 Uncharacterised protein family YqxA UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 122 1.4E-44 T 11-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 124 2.6E-53 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 SUPERFAMILY SSF81330 11 118 2.22E-34 T 11-10-2018 IPR036019 Gated mechanosensitive channel UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 2.8E-12 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.8E-12 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 2.8E-12 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 Gene3D G3DSA:1.10.1200.120 1 125 9.8E-42 T 11-10-2018 IPR036019 Gated mechanosensitive channel UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 123 23.982 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 UP12_16985 c40945e2bc7f5667507266ca8e01ff44 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 11-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site UP12_18080 1e618329ba96e0948ebc2293b0130ad4 250 Pfam PF04203 Sortase family 82 246 2.0E-19 T 11-10-2018 IPR005754 Sortase family UP12_18080 1e618329ba96e0948ebc2293b0130ad4 250 PIRSF PIRSF030150 2 248 3.7E-89 T 11-10-2018 IPR015986 Sortase B, Firmicutes UP12_18080 1e618329ba96e0948ebc2293b0130ad4 250 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 6 242 1.1E-81 T 11-10-2018 IPR009835 Sortase B family UP12_18080 1e618329ba96e0948ebc2293b0130ad4 250 Gene3D G3DSA:2.40.260.10 29 248 1.0E-73 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_18080 1e618329ba96e0948ebc2293b0130ad4 250 SUPERFAMILY SSF63817 16 246 9.94E-68 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_15815 1f888a75d9f747522eded0792e8ff9b8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 4.7E-13 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UP12_15815 1f888a75d9f747522eded0792e8ff9b8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 4.7E-13 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UP12_15815 1f888a75d9f747522eded0792e8ff9b8 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 4.7E-13 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UP12_15815 1f888a75d9f747522eded0792e8ff9b8 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 75 6.8E-24 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UP12_15815 1f888a75d9f747522eded0792e8ff9b8 77 Pfam PF03840 Preprotein translocase SecG subunit 4 75 6.1E-23 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 SMART SM00533 9 315 1.5E-42 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 Pfam PF01713 Smr domain 710 785 1.8E-20 T 11-10-2018 IPR002625 Smr domain UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 SUPERFAMILY SSF48334 18 287 1.22E-28 T 11-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 Gene3D G3DSA:1.10.1420.10 134 259 1.5E-8 T 11-10-2018 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 785 0.0 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 PIRSF PIRSF005814 1 785 2.3E-287 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 SMART SM00534 328 513 2.2E-81 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 Gene3D G3DSA:1.10.1420.10 35 283 1.5E-8 T 11-10-2018 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 Gene3D G3DSA:3.40.50.300 292 598 3.1E-87 T 11-10-2018 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 Gene3D G3DSA:3.30.1370.110 698 785 2.3E-24 T 11-10-2018 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 SUPERFAMILY SSF160443 708 784 2.22E-9 T 11-10-2018 IPR036063 Smr domain superfamily UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 784 22.525 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 410 426 - T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 Pfam PF00488 MutS domain V 331 512 3.9E-36 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 SMART SM00463 707 785 2.3E-23 T 11-10-2018 IPR002625 Smr domain UP12_12890 9a1281cb2ad32f4c1c9414ad54c28d00 785 SUPERFAMILY SSF52540 292 512 2.61E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10270 a23baa6ac297ef5a7a47bd3ea018beca 294 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 280 2.0E-110 T 11-10-2018 UP12_10270 a23baa6ac297ef5a7a47bd3ea018beca 294 Pfam PF14045 YIEGIA protein 8 287 1.9E-125 T 11-10-2018 IPR025918 YIEGIA protein UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 SUPERFAMILY SSF53335 58 261 6.2E-39 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 SMART SM00487 474 662 4.6E-11 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 157 163 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 Gene3D G3DSA:3.40.50.300 742 997 3.8E-21 T 11-10-2018 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 SUPERFAMILY SSF52540 493 927 3.06E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 154 166 2.7E-15 T 11-10-2018 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 74 90 2.7E-15 T 11-10-2018 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 98 112 2.7E-15 T 11-10-2018 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 175 199 2.7E-15 T 11-10-2018 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 Gene3D G3DSA:3.40.50.150 56 361 8.3E-33 T 11-10-2018 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 SMART SM00490 840 925 0.0045 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 Pfam PF00176 SNF2 family N-terminal domain 502 770 2.5E-11 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 Pfam PF02384 N-6 DNA Methylase 67 249 4.4E-10 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 Pfam PF00271 Helicase conserved C-terminal domain 818 924 5.9E-7 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_19565 8049546a6bbaf07d4a14d7af27eed4e1 1007 Gene3D G3DSA:3.40.50.300 466 651 5.8E-20 T 11-10-2018 UP12_07645 12ab9c22dda0d3797eb251d8096fb1e7 405 Gene3D G3DSA:3.40.50.10300 186 403 1.1E-82 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UP12_07645 12ab9c22dda0d3797eb251d8096fb1e7 405 SUPERFAMILY SSF52507 1 179 7.72E-63 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UP12_07645 12ab9c22dda0d3797eb251d8096fb1e7 405 Pfam PF02441 Flavoprotein 5 177 6.0E-48 T 11-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UP12_07645 12ab9c22dda0d3797eb251d8096fb1e7 405 SUPERFAMILY SSF102645 186 399 3.79E-75 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UP12_07645 12ab9c22dda0d3797eb251d8096fb1e7 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 393 2.1E-158 T 11-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 UP12_07645 12ab9c22dda0d3797eb251d8096fb1e7 405 Gene3D G3DSA:3.40.50.1950 1 185 3.2E-62 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UP12_07645 12ab9c22dda0d3797eb251d8096fb1e7 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 188 369 3.3E-73 T 11-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 UP12_03895 8a4043d67275dd2e85a9cf70f6a62d24 368 PIRSF PIRSF037219 1 368 2.0E-189 T 11-10-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 UP12_03895 8a4043d67275dd2e85a9cf70f6a62d24 368 SUPERFAMILY SSF56512 3 363 1.83E-171 T 11-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UP12_03895 8a4043d67275dd2e85a9cf70f6a62d24 368 Gene3D G3DSA:3.90.1230.10 194 300 7.4E-156 T 11-10-2018 UP12_03895 8a4043d67275dd2e85a9cf70f6a62d24 368 Gene3D G3DSA:3.90.440.10 83 193 7.4E-156 T 11-10-2018 UP12_03895 8a4043d67275dd2e85a9cf70f6a62d24 368 Gene3D G3DSA:3.90.340.10 6 355 7.4E-156 T 11-10-2018 UP12_03895 8a4043d67275dd2e85a9cf70f6a62d24 368 Pfam PF02898 Nitric oxide synthase, oxygenase domain 4 362 2.7E-174 T 11-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UP12_03895 8a4043d67275dd2e85a9cf70f6a62d24 368 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 66 73 - T 11-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 UP12_05555 4dc592c224c7fd735c1747e45e69dfbb 481 Pfam PF01565 FAD binding domain 52 184 1.4E-32 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UP12_05555 4dc592c224c7fd735c1747e45e69dfbb 481 SUPERFAMILY SSF56176 36 211 3.41E-41 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UP12_05555 4dc592c224c7fd735c1747e45e69dfbb 481 Gene3D G3DSA:3.30.465.10 104 227 1.6E-29 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UP12_05555 4dc592c224c7fd735c1747e45e69dfbb 481 Pfam PF04030 D-arabinono-1,4-lactone oxidase 216 477 1.8E-4 T 11-10-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 UP12_05555 4dc592c224c7fd735c1747e45e69dfbb 481 SUPERFAMILY SSF55103 190 469 4.58E-17 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UP12_00220 7fd43ce89fd1a1865ad03cfb4ee1fc2e 329 SUPERFAMILY SSF52540 11 197 1.0E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00220 7fd43ce89fd1a1865ad03cfb4ee1fc2e 329 Gene3D G3DSA:3.40.50.300 8 169 2.0E-51 T 11-10-2018 UP12_00220 7fd43ce89fd1a1865ad03cfb4ee1fc2e 329 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 240 326 6.9E-6 T 11-10-2018 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_00220 7fd43ce89fd1a1865ad03cfb4ee1fc2e 329 Pfam PF13177 DNA polymerase III, delta subunit 12 169 4.1E-56 T 11-10-2018 UP12_00220 7fd43ce89fd1a1865ad03cfb4ee1fc2e 329 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 19 197 9.4E-64 T 11-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_17665 0f101a24449927ce103979a440833871 374 Pfam PF03102 NeuB family 37 272 1.8E-78 T 11-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 UP12_17665 0f101a24449927ce103979a440833871 374 Pfam PF08666 SAF domain 309 365 1.9E-9 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UP12_17665 0f101a24449927ce103979a440833871 374 SUPERFAMILY SSF51569 4 275 7.64E-83 T 11-10-2018 UP12_17665 0f101a24449927ce103979a440833871 374 SMART SM00858 305 366 7.7E-6 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UP12_17665 0f101a24449927ce103979a440833871 374 Gene3D G3DSA:3.90.1210.10 306 373 6.9E-24 T 11-10-2018 UP12_17665 0f101a24449927ce103979a440833871 374 SUPERFAMILY SSF51269 300 365 6.91E-17 T 11-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 UP12_17665 0f101a24449927ce103979a440833871 374 Gene3D G3DSA:3.20.20.70 1 305 9.8E-112 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_06735 632a760fc38862e170afcc23c4fce4f6 289 PIRSF PIRSF000103 1 288 2.7E-73 T 11-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 UP12_06735 632a760fc38862e170afcc23c4fce4f6 289 SUPERFAMILY SSF48179 165 287 7.25E-39 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_06735 632a760fc38862e170afcc23c4fce4f6 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 167 287 1.5E-35 T 11-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 UP12_06735 632a760fc38862e170afcc23c4fce4f6 289 Gene3D G3DSA:3.40.50.720 2 164 1.8E-52 T 11-10-2018 UP12_06735 632a760fc38862e170afcc23c4fce4f6 289 SUPERFAMILY SSF51735 5 165 9.33E-49 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06735 632a760fc38862e170afcc23c4fce4f6 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 162 6.3E-52 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UP12_06735 632a760fc38862e170afcc23c4fce4f6 289 Gene3D G3DSA:1.10.1040.10 165 289 9.5E-41 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 Gene3D G3DSA:3.90.230.10 128 353 8.5E-88 T 11-10-2018 UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 11-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 Gene3D G3DSA:3.40.350.10 1 127 5.7E-37 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 Pfam PF00557 Metallopeptidase family M24 136 337 3.5E-67 T 11-10-2018 IPR000994 Peptidase M24 UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 2.0E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 2.0E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 127 3.1E-30 T 11-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 UP12_11060 4977d6ede51881a2b497ebd81f5e5eb5 353 SUPERFAMILY SSF55920 80 348 6.93E-86 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Pfam PF00476 DNA polymerase family A 502 877 2.8E-162 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SMART SM00475 5 264 5.6E-151 T 11-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Gene3D G3DSA:1.10.150.20 176 249 5.6E-99 T 11-10-2018 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Gene3D G3DSA:1.10.150.20 660 803 1.4E-110 T 11-10-2018 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 TIGRFAM TIGR00593 pola: DNA polymerase I 7 879 0.0 T 11-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SUPERFAMILY SSF47807 173 288 7.92E-35 T 11-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SMART SM00474 291 469 1.6E-14 T 11-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SUPERFAMILY SSF56672 473 879 1.45E-158 T 11-10-2018 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 694 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 628 643 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 605 627 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 839 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 730 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 674 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 742 753 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 812 1.4E-80 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SMART SM00482 636 843 3.9E-120 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Gene3D G3DSA:3.30.70.370 614 875 1.4E-110 T 11-10-2018 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Gene3D G3DSA:1.20.1060.10 494 608 3.1E-44 T 11-10-2018 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 172 5.4E-53 T 11-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SUPERFAMILY SSF53098 312 470 4.7E-41 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 ProSitePatterns PS00447 DNA polymerase family A signature. 705 724 - T 11-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Gene3D G3DSA:3.30.420.10 302 492 4.1E-58 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SUPERFAMILY SSF88723 3 172 8.18E-55 T 11-10-2018 IPR029060 PIN-like domain superfamily UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 174 267 4.6E-35 T 11-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 Gene3D G3DSA:3.40.50.1010 7 280 5.6E-99 T 11-10-2018 UP12_13060 7cf66dac0849dbe2dd708f2a945efcb9 879 SMART SM00279 175 210 2.6E-18 T 11-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 UP12_10245 b51c5e69f9fd744c23418b23a5a46014 241 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 15 237 3.0E-81 T 11-10-2018 UP12_15205 87e7c2c323e8195fb575c6ba717ec725 166 Pfam PF04608 Phosphatidylglycerophosphatase A 23 159 9.8E-19 T 11-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 UP12_15205 87e7c2c323e8195fb575c6ba717ec725 166 PIRSF PIRSF019587 5 166 1.3E-79 T 11-10-2018 IPR026038 Putative phosphatidylglycerophosphatase UP12_15205 87e7c2c323e8195fb575c6ba717ec725 166 SUPERFAMILY SSF101307 11 162 7.98E-54 T 11-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 UP12_15205 87e7c2c323e8195fb575c6ba717ec725 166 Gene3D G3DSA:1.10.3760.10 3 166 3.0E-74 T 11-10-2018 UP12_16275 cb33827ba577ebbeca5633f873292c6f 213 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 11-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 UP12_16275 cb33827ba577ebbeca5633f873292c6f 213 Pfam PF01634 ATP phosphoribosyltransferase 54 204 4.4E-49 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UP12_16275 cb33827ba577ebbeca5633f873292c6f 213 Gene3D G3DSA:3.40.190.10 95 176 2.0E-80 T 11-10-2018 UP12_16275 cb33827ba577ebbeca5633f873292c6f 213 SUPERFAMILY SSF53850 3 207 1.32E-65 T 11-10-2018 UP12_16275 cb33827ba577ebbeca5633f873292c6f 213 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 5 184 1.9E-61 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 UP12_16275 cb33827ba577ebbeca5633f873292c6f 213 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 4 208 57.086 T 11-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 UP12_16275 cb33827ba577ebbeca5633f873292c6f 213 Gene3D G3DSA:3.40.190.10 6 199 2.0E-80 T 11-10-2018 UP12_11525 675dfed650dcc55d51240b067f751629 149 SUPERFAMILY SSF89095 1 147 3.03E-41 T 11-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 UP12_11525 675dfed650dcc55d51240b067f751629 149 Gene3D G3DSA:1.10.10.410 92 148 2.7E-26 T 11-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal UP12_11525 675dfed650dcc55d51240b067f751629 149 Gene3D G3DSA:1.10.1510.10 1 91 9.1E-30 T 11-10-2018 UP12_11525 675dfed650dcc55d51240b067f751629 149 Pfam PF09424 Yqey-like protein 5 147 2.0E-51 T 11-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 UP12_13265 8fc5402883a6d53eb73db830b87345db 334 Gene3D G3DSA:3.30.565.10 170 323 2.3E-33 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13265 8fc5402883a6d53eb73db830b87345db 334 SUPERFAMILY SSF47384 103 161 8.24E-5 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_13265 8fc5402883a6d53eb73db830b87345db 334 SUPERFAMILY SSF55874 175 323 8.51E-31 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13265 8fc5402883a6d53eb73db830b87345db 334 SMART SM00387 216 326 2.3E-22 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_13265 8fc5402883a6d53eb73db830b87345db 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 217 325 1.0E-19 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_13265 8fc5402883a6d53eb73db830b87345db 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 280 1.2E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13265 8fc5402883a6d53eb73db830b87345db 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 252 266 1.2E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13265 8fc5402883a6d53eb73db830b87345db 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 286 304 1.2E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13265 8fc5402883a6d53eb73db830b87345db 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 323 1.2E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13265 8fc5402883a6d53eb73db830b87345db 334 Gene3D G3DSA:1.10.287.130 123 169 2.3E-33 T 11-10-2018 UP12_07250 35d79fba6c1cf0dfeeb80e5a975f2c1f 137 Pfam PF14071 Putative coat protein 11 137 1.4E-44 T 11-10-2018 IPR025953 Putative coat protein YlbD UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 Pfam PF00107 Zinc-binding dehydrogenase 173 300 1.3E-23 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 Gene3D G3DSA:3.40.50.720 149 286 5.1E-95 T 11-10-2018 UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 Gene3D G3DSA:3.90.180.10 11 325 5.1E-95 T 11-10-2018 UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 SUPERFAMILY SSF51735 137 303 4.62E-35 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 125 3.6E-28 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 SMART SM00829 8 339 2.8E-6 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 SUPERFAMILY SSF50129 1 171 7.76E-46 T 11-10-2018 IPR011032 GroES-like superfamily UP12_06210 1f0bb91ef851178106b4bcc2184094e7 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 56 70 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 304 9.4E-10 T 11-10-2018 IPR010918 PurM-like, C-terminal domain UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 PIRSF PIRSF005303 1 323 1.3E-96 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 SUPERFAMILY SSF56042 144 308 7.48E-30 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 323 9.4E-108 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 Gene3D G3DSA:3.90.650.10 146 323 1.2E-44 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 SUPERFAMILY SSF55326 2 139 1.13E-32 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 323 28.449 T 11-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 Pfam PF00586 AIR synthase related protein, N-terminal domain 26 139 1.1E-21 T 11-10-2018 IPR016188 PurM-like, N-terminal domain UP12_03120 7eff44fc67ffc2d28730db3b6026a7bc 325 Gene3D G3DSA:3.30.1330.10 1 145 4.6E-42 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_14830 7770b5c1a8748d006618e13fa65dfd26 86 Gene3D G3DSA:1.10.340.20 1 86 2.8E-30 T 11-10-2018 IPR023162 Apc36109-like domain superfamily UP12_14830 7770b5c1a8748d006618e13fa65dfd26 86 ProDom PD062625 YUGE 9 85 1.0E-21 T 11-10-2018 IPR015053 Protein of unknown function DUF1871 UP12_14830 7770b5c1a8748d006618e13fa65dfd26 86 SUPERFAMILY SSF116922 4 82 4.58E-27 T 11-10-2018 IPR023162 Apc36109-like domain superfamily UP12_14830 7770b5c1a8748d006618e13fa65dfd26 86 Pfam PF08958 Domain of unknown function (DUF1871) 9 85 4.7E-38 T 11-10-2018 IPR015053 Protein of unknown function DUF1871 UP12_07910 17b97bea89e800875190863ee3d11671 438 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_07910 17b97bea89e800875190863ee3d11671 438 SMART SM00382 157 338 1.3E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_07910 17b97bea89e800875190863ee3d11671 438 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 3.5E-77 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_07910 17b97bea89e800875190863ee3d11671 438 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 23 88 1.6E-5 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_07910 17b97bea89e800875190863ee3d11671 438 SUPERFAMILY SSF52540 92 359 5.56E-95 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07910 17b97bea89e800875190863ee3d11671 438 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 20 431 3.5E-204 T 11-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_07910 17b97bea89e800875190863ee3d11671 438 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 12 430 2.4E-200 T 11-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_07910 17b97bea89e800875190863ee3d11671 438 Gene3D G3DSA:3.40.50.12240 11 436 1.3E-153 T 11-10-2018 UP12_11105 f74e78131cf290e7a305508b4d45ff15 485 SUPERFAMILY SSF53383 11 482 7.4E-115 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_11105 f74e78131cf290e7a305508b4d45ff15 485 Gene3D G3DSA:3.40.640.10 86 313 4.1E-57 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_11105 f74e78131cf290e7a305508b4d45ff15 485 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 7 485 59.832 T 11-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 UP12_11105 f74e78131cf290e7a305508b4d45ff15 485 Pfam PF02347 Glycine cleavage system P-protein 45 299 1.2E-7 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UP12_11105 f74e78131cf290e7a305508b4d45ff15 485 Gene3D G3DSA:3.90.1150.10 339 470 3.5E-48 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_14510 de316ffdf5a2e7cf6962ff434ef3a156 267 SUPERFAMILY SSF47090 192 262 9.42E-16 T 11-10-2018 IPR036365 PGBD-like superfamily UP12_14510 de316ffdf5a2e7cf6962ff434ef3a156 267 SUPERFAMILY SSF55846 1 153 1.44E-45 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_14510 de316ffdf5a2e7cf6962ff434ef3a156 267 Gene3D G3DSA:3.40.80.10 1 154 8.5E-54 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_14510 de316ffdf5a2e7cf6962ff434ef3a156 267 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 22 140 9.6E-24 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_14510 de316ffdf5a2e7cf6962ff434ef3a156 267 SMART SM00644 13 153 2.8E-32 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 UP12_14510 de316ffdf5a2e7cf6962ff434ef3a156 267 Pfam PF01471 Putative peptidoglycan binding domain 200 261 3.0E-17 T 11-10-2018 IPR002477 Peptidoglycan binding-like UP12_14510 de316ffdf5a2e7cf6962ff434ef3a156 267 Gene3D G3DSA:1.10.101.10 189 267 1.2E-17 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UP12_05330 cc0e0bd79a7c0a932a4a71dfd357ea02 1131 SUPERFAMILY SSF52540 28 1114 1.75E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05330 cc0e0bd79a7c0a932a4a71dfd357ea02 1131 Pfam PF13555 P-loop containing region of AAA domain 13 62 4.9E-7 T 11-10-2018 UP12_05330 cc0e0bd79a7c0a932a4a71dfd357ea02 1131 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1003 1086 5.4E-15 T 11-10-2018 UP12_05330 cc0e0bd79a7c0a932a4a71dfd357ea02 1131 Gene3D G3DSA:3.40.50.300 860 1127 3.0E-27 T 11-10-2018 UP12_05330 cc0e0bd79a7c0a932a4a71dfd357ea02 1131 Gene3D G3DSA:3.40.50.300 2 287 2.0E-40 T 11-10-2018 UP12_10070 bfde24b04cbd1052ffa69bc9801781ab 381 SUPERFAMILY SSF53756 8 376 2.59E-92 T 11-10-2018 UP12_10070 bfde24b04cbd1052ffa69bc9801781ab 381 Pfam PF13439 Glycosyltransferase Family 4 14 178 1.5E-28 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UP12_10070 bfde24b04cbd1052ffa69bc9801781ab 381 Gene3D G3DSA:3.40.50.2000 176 357 2.2E-129 T 11-10-2018 UP12_10070 bfde24b04cbd1052ffa69bc9801781ab 381 Gene3D G3DSA:3.40.50.2000 14 368 2.2E-129 T 11-10-2018 UP12_10070 bfde24b04cbd1052ffa69bc9801781ab 381 Pfam PF00534 Glycosyl transferases group 1 190 350 3.2E-43 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 UP12_10070 bfde24b04cbd1052ffa69bc9801781ab 381 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 4 374 4.5E-177 T 11-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 UP12_05650 35e35807aa0cc542dc892a2703eb450a 267 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 67 260 1.1E-67 T 11-10-2018 IPR018728 Domain of unknown function DUF2268 UP12_13165 711ac77b7f1b2d7880a1e97f9dd2c9b6 227 SUPERFAMILY SSF56281 1 221 5.5E-31 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_13165 711ac77b7f1b2d7880a1e97f9dd2c9b6 227 Gene3D G3DSA:3.60.15.10 1 227 2.8E-68 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_13165 711ac77b7f1b2d7880a1e97f9dd2c9b6 227 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 227 36.149 T 11-10-2018 IPR022877 Protein of unknown funcion UPF0173 UP12_13165 711ac77b7f1b2d7880a1e97f9dd2c9b6 227 Pfam PF13483 Beta-lactamase superfamily domain 4 193 5.4E-24 T 11-10-2018 UP12_13165 711ac77b7f1b2d7880a1e97f9dd2c9b6 227 SMART SM00849 7 193 2.3E-8 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Pfam PF02574 Homocysteine S-methyltransferase 13 302 7.6E-73 T 11-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 SUPERFAMILY SSF51717 335 597 1.7E-77 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 SUPERFAMILY SSF56507 862 1141 1.96E-88 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 894 1141 1.7E-55 T 11-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 SUPERFAMILY SSF82282 2 377 1.83E-110 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Pfam PF02607 B12 binding domain 625 698 4.5E-21 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Gene3D G3DSA:3.40.50.280 707 847 3.6E-45 T 11-10-2018 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Gene3D G3DSA:3.10.196.10 878 1141 3.9E-64 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Gene3D G3DSA:1.10.288.10 892 950 3.9E-64 T 11-10-2018 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 PIRSF PIRSF000381 1 1142 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Gene3D G3DSA:3.20.20.330 1 318 2.0E-107 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Pfam PF00809 Pterin binding enzyme 338 571 1.3E-37 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 SUPERFAMILY SSF52242 706 835 9.55E-39 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Gene3D G3DSA:1.10.1240.10 615 702 3.3E-25 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 SUPERFAMILY SSF47644 622 704 2.22E-21 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Pfam PF02310 B12 binding domain 711 803 1.6E-19 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 Gene3D G3DSA:3.20.20.20 319 614 1.2E-101 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 SMART SM01018 622 705 7.1E-36 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_05485 836ffdc1e3d3510cf936b2b52a90e3d1 1142 TIGRFAM TIGR02082 metH: methionine synthase 8 1141 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_16125 0c63cfc20daf612bcaadfa6146efe646 389 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 194 359 2.9E-19 T 11-10-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0016758 Reactome: R-HSA-156588 UP12_16125 0c63cfc20daf612bcaadfa6146efe646 389 Gene3D G3DSA:3.40.50.2000 5 378 2.0E-102 T 11-10-2018 UP12_16125 0c63cfc20daf612bcaadfa6146efe646 389 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 8 382 2.7E-92 T 11-10-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 UP12_16125 0c63cfc20daf612bcaadfa6146efe646 389 SUPERFAMILY SSF53756 3 382 1.26E-76 T 11-10-2018 UP12_16125 0c63cfc20daf612bcaadfa6146efe646 389 Gene3D G3DSA:3.40.50.2000 204 367 2.0E-102 T 11-10-2018 UP12_00920 68adb6675584a3dfc2acf48e3d3e87dc 338 Pfam PF13354 Beta-lactamase enzyme family 34 245 1.8E-19 T 11-10-2018 UP12_00920 68adb6675584a3dfc2acf48e3d3e87dc 338 SUPERFAMILY SSF56601 19 311 7.34E-20 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 PIRSF PIRSF000102 2 311 7.7E-105 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 9.3E-31 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 9.3E-31 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 9.3E-31 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 9.3E-31 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 9.3E-31 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 SUPERFAMILY SSF56327 151 309 3.89E-53 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 Gene3D G3DSA:3.90.110.10 150 310 1.2E-61 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 Gene3D G3DSA:3.40.50.720 1 149 1.3E-60 T 11-10-2018 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 9.1E-171 T 11-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 152 309 7.7E-28 T 11-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 SUPERFAMILY SSF51735 7 147 3.6E-47 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 6.1E-41 T 11-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_13075 f7d791403f6183b85b72b7f0c3649a8f 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 47.179 T 11-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 UP12_17125 cc593009abd204355188762752b3e08d 262 PIRSF PIRSF015626 1 262 5.3E-81 T 11-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UP12_17125 cc593009abd204355188762752b3e08d 262 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 3 261 31.397 T 11-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UP12_17125 cc593009abd204355188762752b3e08d 262 Gene3D G3DSA:3.10.20.10 29 111 1.6E-13 T 11-10-2018 UP12_17125 cc593009abd204355188762752b3e08d 262 Gene3D G3DSA:3.40.140.10 116 262 2.0E-49 T 11-10-2018 UP12_17125 cc593009abd204355188762752b3e08d 262 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 261 7.9E-85 T 11-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UP12_17125 cc593009abd204355188762752b3e08d 262 SUPERFAMILY SSF53927 7 260 5.72E-78 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_17125 cc593009abd204355188762752b3e08d 262 Pfam PF02634 FdhD/NarQ family 27 260 4.8E-78 T 11-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 UP12_05190 daa070a79c4bad0b8defba53a02d2f33 329 SUPERFAMILY SSF55681 2 241 6.75E-81 T 11-10-2018 UP12_05190 daa070a79c4bad0b8defba53a02d2f33 329 SUPERFAMILY SSF82649 243 329 1.78E-29 T 11-10-2018 UP12_05190 daa070a79c4bad0b8defba53a02d2f33 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 2 323 3.4E-137 T 11-10-2018 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 KEGG: 00785+6.3.1.20|Reactome: R-HSA-389661 UP12_05190 daa070a79c4bad0b8defba53a02d2f33 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 48 151 4.5E-12 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UP12_05190 daa070a79c4bad0b8defba53a02d2f33 329 Gene3D G3DSA:3.30.930.10 3 242 1.6E-81 T 11-10-2018 UP12_05190 daa070a79c4bad0b8defba53a02d2f33 329 Gene3D G3DSA:3.30.390.50 243 329 4.5E-33 T 11-10-2018 UP12_05190 daa070a79c4bad0b8defba53a02d2f33 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 328 7.2E-33 T 11-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 UP12_12130 55365dc964303c45732120f7a83dc02d 88 Pfam PF02699 Preprotein translocase subunit 7 82 2.4E-30 T 11-10-2018 IPR003849 Preprotein translocase YajC UP12_12130 55365dc964303c45732120f7a83dc02d 88 SMART SM01323 3 85 4.1E-41 T 11-10-2018 IPR003849 Preprotein translocase YajC UP12_12130 55365dc964303c45732120f7a83dc02d 88 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 5 84 4.2E-32 T 11-10-2018 IPR003849 Preprotein translocase YajC UP12_12130 55365dc964303c45732120f7a83dc02d 88 PRINTS PR01853 Bacterial YajC preprotein translocase signature 43 61 3.4E-14 T 11-10-2018 IPR003849 Preprotein translocase YajC UP12_12130 55365dc964303c45732120f7a83dc02d 88 PRINTS PR01853 Bacterial YajC preprotein translocase signature 5 25 3.4E-14 T 11-10-2018 IPR003849 Preprotein translocase YajC UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 11-10-2018 IPR014762 DNA mismatch repair, conserved site UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 SUPERFAMILY SSF118116 443 631 1.11E-55 T 11-10-2018 IPR037198 MutL, C-terminal domain superfamily UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Gene3D G3DSA:3.30.1370.100 489 582 1.3E-67 T 11-10-2018 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Pfam PF08676 MutL C terminal dimerisation domain 448 589 8.5E-48 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 629 27.563 T 11-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 SUPERFAMILY SSF55874 2 213 6.68E-52 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 113 5.3E-8 T 11-10-2018 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 SMART SM01340 208 326 2.4E-51 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Gene3D G3DSA:3.30.565.10 1 212 1.4E-62 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Gene3D G3DSA:2.30.42.20 448 631 1.3E-67 T 11-10-2018 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Gene3D G3DSA:3.30.230.10 213 325 2.1E-31 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 5.9E-100 T 11-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 SUPERFAMILY SSF54211 190 326 4.93E-36 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 7.6E-36 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 UP12_08360 f753ae4775d2a725a1dbe9b6e5ff3c61 633 SMART SM00853 447 589 1.5E-55 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 UP12_16440 a1193576da1662a4af0c5357f5c608f0 395 SMART SM00228 293 359 7.2E-4 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_16440 a1193576da1662a4af0c5357f5c608f0 395 Gene3D G3DSA:2.30.42.10 282 376 1.9E-10 T 11-10-2018 UP12_16440 a1193576da1662a4af0c5357f5c608f0 395 SUPERFAMILY SSF50156 301 386 8.15E-13 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_10280 7cec3ec9c2e498083deafed250c99622 355 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 38.39 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 UP12_10280 7cec3ec9c2e498083deafed250c99622 355 SUPERFAMILY SSF51395 24 347 1.83E-84 T 11-10-2018 UP12_10280 7cec3ec9c2e498083deafed250c99622 355 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 2.3E-118 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 UP12_10280 7cec3ec9c2e498083deafed250c99622 355 PIRSF PIRSF003314 1 340 4.7E-122 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 UP12_10280 7cec3ec9c2e498083deafed250c99622 355 SMART SM01240 23 336 0.0052 T 11-10-2018 UP12_10280 7cec3ec9c2e498083deafed250c99622 355 Gene3D G3DSA:3.20.20.70 2 353 1.1E-125 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_10280 7cec3ec9c2e498083deafed250c99622 355 Pfam PF01070 FMN-dependent dehydrogenase 166 324 4.3E-20 T 11-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 1.4E-204 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 PIRSF PIRSF000130 1 488 2.7E-210 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 SMART SM00116 98 148 4.4E-7 T 11-10-2018 IPR000644 CBS domain UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 SMART SM00116 161 209 1.4E-7 T 11-10-2018 IPR000644 CBS domain UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 SMART SM01240 9 474 0.0 T 11-10-2018 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 SUPERFAMILY SSF51412 5 157 1.01E-29 T 11-10-2018 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 2.7E-167 T 11-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 Pfam PF00571 CBS domain 97 144 3.7E-6 T 11-10-2018 IPR000644 CBS domain UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 Pfam PF00571 CBS domain 153 204 1.0E-7 T 11-10-2018 IPR000644 CBS domain UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 84.712 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 11-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 Gene3D G3DSA:3.20.20.70 1 487 3.2E-226 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_00070 d7b0bfae295b4068e6d295cac116f717 488 SUPERFAMILY SSF51412 139 485 9.81E-126 T 11-10-2018 UP12_06580 59f19d0e06639ca815ac583cc7af8654 212 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 12 203 1.8E-65 T 11-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 UP12_06580 59f19d0e06639ca815ac583cc7af8654 212 Gene3D G3DSA:3.40.225.10 4 210 2.1E-49 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UP12_06580 59f19d0e06639ca815ac583cc7af8654 212 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 209 104.988 T 11-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 UP12_06580 59f19d0e06639ca815ac583cc7af8654 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 10 200 4.5E-38 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal UP12_06580 59f19d0e06639ca815ac583cc7af8654 212 SMART SM01007 10 201 7.3E-46 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal UP12_06580 59f19d0e06639ca815ac583cc7af8654 212 SUPERFAMILY SSF53639 7 207 5.3E-44 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UP12_13355 a93b0a204b4f51718bcad0c62c41e3a5 165 Gene3D G3DSA:3.30.450.40 11 165 2.7E-64 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_13355 a93b0a204b4f51718bcad0c62c41e3a5 165 SMART SM00065 31 165 1.7E-5 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_13355 a93b0a204b4f51718bcad0c62c41e3a5 165 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 11-10-2018 IPR000614 Free Met sulfoxide reductase conserved site UP12_13355 a93b0a204b4f51718bcad0c62c41e3a5 165 SUPERFAMILY SSF55781 15 159 8.94E-43 T 11-10-2018 UP12_13355 a93b0a204b4f51718bcad0c62c41e3a5 165 Pfam PF13185 GAF domain 66 159 3.8E-11 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_18875 2988933c56418c475a6f18819719fe72 264 SMART SM00849 13 218 2.1E-15 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_18875 2988933c56418c475a6f18819719fe72 264 Pfam PF00753 Metallo-beta-lactamase superfamily 12 218 1.7E-28 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_18875 2988933c56418c475a6f18819719fe72 264 Gene3D G3DSA:3.60.15.10 8 250 1.3E-41 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_18875 2988933c56418c475a6f18819719fe72 264 SUPERFAMILY SSF56281 1 243 7.47E-45 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_17030 9ddcd8aaa39ab52b3021316b7e4223f1 199 Pfam PF01569 PAP2 superfamily 59 162 7.4E-15 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UP12_17030 9ddcd8aaa39ab52b3021316b7e4223f1 199 SUPERFAMILY SSF48317 2 166 5.1E-33 T 11-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily UP12_17030 9ddcd8aaa39ab52b3021316b7e4223f1 199 SMART SM00014 49 160 5.9E-20 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UP12_17030 9ddcd8aaa39ab52b3021316b7e4223f1 199 Gene3D G3DSA:1.20.144.10 73 175 7.6E-17 T 11-10-2018 UP12_07090 abc1fcd828977220d4260a6d3d55d4aa 490 SUPERFAMILY SSF53383 6 382 2.58E-95 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_07090 abc1fcd828977220d4260a6d3d55d4aa 490 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 384 457 1.9E-12 T 11-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 UP12_07090 abc1fcd828977220d4260a6d3d55d4aa 490 SUPERFAMILY SSF55904 341 486 1.18E-38 T 11-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 UP12_07090 abc1fcd828977220d4260a6d3d55d4aa 490 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 11-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 UP12_07090 abc1fcd828977220d4260a6d3d55d4aa 490 Gene3D G3DSA:3.90.100.10 387 487 7.4E-19 T 11-10-2018 UP12_07090 abc1fcd828977220d4260a6d3d55d4aa 490 Gene3D G3DSA:3.40.640.10 6 282 9.9E-93 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_07090 abc1fcd828977220d4260a6d3d55d4aa 490 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 369 1.7E-115 T 11-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 UP12_04045 9dcd7999256e7c21eab81f6af89e3147 373 Gene3D G3DSA:3.20.20.70 22 300 3.5E-23 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_04045 9dcd7999256e7c21eab81f6af89e3147 373 Pfam PF04055 Radical SAM superfamily 37 175 8.7E-12 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_04045 9dcd7999256e7c21eab81f6af89e3147 373 Pfam PF13353 4Fe-4S single cluster domain 41 135 5.0E-6 T 11-10-2018 UP12_04045 9dcd7999256e7c21eab81f6af89e3147 373 SUPERFAMILY SSF102114 30 320 2.49E-27 T 11-10-2018 UP12_04045 9dcd7999256e7c21eab81f6af89e3147 373 Pfam PF08756 YfkB-like domain 221 370 1.7E-77 T 11-10-2018 IPR014866 YfkB-like domain UP12_04045 9dcd7999256e7c21eab81f6af89e3147 373 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 9 370 2.3E-196 T 11-10-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB UP12_13325 b8ff0088706909fa32e0affbe49a6979 380 Gene3D G3DSA:3.90.1150.10 2 355 1.2E-123 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_13325 b8ff0088706909fa32e0affbe49a6979 380 Gene3D G3DSA:3.40.640.10 59 235 1.2E-123 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_13325 b8ff0088706909fa32e0affbe49a6979 380 PIRSF PIRSF005572 1 379 3.2E-107 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 UP12_13325 b8ff0088706909fa32e0affbe49a6979 380 Pfam PF00266 Aminotransferase class-V 2 354 3.1E-71 T 11-10-2018 IPR000192 Aminotransferase class V domain UP12_13325 b8ff0088706909fa32e0affbe49a6979 380 Gene3D G3DSA:1.10.260.50 13 279 1.2E-123 T 11-10-2018 UP12_13325 b8ff0088706909fa32e0affbe49a6979 380 SUPERFAMILY SSF53383 1 373 1.07E-92 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_18585 a5d9c0f7d8035d42072e8b5eb0811c86 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_18585 a5d9c0f7d8035d42072e8b5eb0811c86 216 SUPERFAMILY SSF48498 107 194 8.26E-7 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_18585 a5d9c0f7d8035d42072e8b5eb0811c86 216 Gene3D G3DSA:1.10.357.10 1 204 8.6E-60 T 11-10-2018 UP12_18585 a5d9c0f7d8035d42072e8b5eb0811c86 216 SUPERFAMILY SSF46689 5 66 1.64E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_18585 a5d9c0f7d8035d42072e8b5eb0811c86 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.4E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_18585 a5d9c0f7d8035d42072e8b5eb0811c86 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.4E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_18585 a5d9c0f7d8035d42072e8b5eb0811c86 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 4.2E-16 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_04865 119b394b56915dc1a8894be857751f76 96 ProDom PD065873 YHDK TRANSCRIPTION ANTI-SIGMA-M REPRESSOR TRANSMEMBRANE MEMBRANE PROBABLE REGULATION FACTOR 1 96 2.0E-39 T 11-10-2018 IPR020496 Probable anti-sigma M factor YhdK UP12_04865 119b394b56915dc1a8894be857751f76 96 Pfam PF17453 Sigma-M inhibitor protein 1 96 5.8E-56 T 11-10-2018 IPR020496 Probable anti-sigma M factor YhdK UP12_01070 001e7e70bb96968d773675551deb1df4 469 Gene3D G3DSA:2.170.120.40 146 231 5.5E-9 T 11-10-2018 UP12_01070 001e7e70bb96968d773675551deb1df4 469 Gene3D G3DSA:2.170.120.40 234 320 1.9E-20 T 11-10-2018 UP12_01070 001e7e70bb96968d773675551deb1df4 469 Gene3D G3DSA:2.170.120.30 42 145 3.8E-27 T 11-10-2018 UP12_01070 001e7e70bb96968d773675551deb1df4 469 Gene3D G3DSA:2.170.120.30 323 419 3.2E-18 T 11-10-2018 UP12_01070 001e7e70bb96968d773675551deb1df4 469 Pfam PF07949 YbbR-like protein 237 316 1.2E-16 T 11-10-2018 IPR012505 YbbR-like UP12_01070 001e7e70bb96968d773675551deb1df4 469 Pfam PF07949 YbbR-like protein 55 135 1.3E-10 T 11-10-2018 IPR012505 YbbR-like UP12_01070 001e7e70bb96968d773675551deb1df4 469 Pfam PF07949 YbbR-like protein 143 228 2.8E-15 T 11-10-2018 IPR012505 YbbR-like UP12_01070 001e7e70bb96968d773675551deb1df4 469 Pfam PF07949 YbbR-like protein 329 410 5.8E-7 T 11-10-2018 IPR012505 YbbR-like UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 Gene3D G3DSA:1.20.150.20 372 499 4.1E-50 T 11-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 SUPERFAMILY SSF47917 372 499 6.28E-46 T 11-10-2018 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 51.126 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 Gene3D G3DSA:2.40.30.20 1 93 5.2E-38 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 SUPERFAMILY SSF52540 95 370 3.38E-98 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 Gene3D G3DSA:3.40.50.300 94 371 8.9E-128 T 11-10-2018 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 SUPERFAMILY SSF50615 10 94 2.94E-31 T 11-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 499 1.1E-260 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 PIRSF PIRSF039088 1 501 9.4E-251 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 1.2E-19 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 2.2E-73 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 UP12_17190 ad5bc4bf6279d51704adcdadb64f1e81 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 485 4.9E-46 T 11-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_15410 df684158121f592f6dc72f52bcdec409 222 Gene3D G3DSA:1.10.3720.10 8 222 5.3E-49 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15410 df684158121f592f6dc72f52bcdec409 222 SUPERFAMILY SSF161098 13 209 8.11E-47 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15410 df684158121f592f6dc72f52bcdec409 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 221 3.1E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_17585 daacc58056ab4721928ee325cd580048 256 Gene3D G3DSA:3.30.70.1100 131 256 6.1E-55 T 11-10-2018 UP12_17585 daacc58056ab4721928ee325cd580048 256 Pfam PF06778 Chlorite dismutase 39 245 1.4E-76 T 11-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase UP12_17585 daacc58056ab4721928ee325cd580048 256 Hamap MF_01442 Putative heme-dependent peroxidase . 7 256 56.499 T 11-10-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family UP12_17585 daacc58056ab4721928ee325cd580048 256 Gene3D G3DSA:3.30.70.1030 3 123 3.7E-46 T 11-10-2018 UP12_17585 daacc58056ab4721928ee325cd580048 256 SUPERFAMILY SSF54909 7 255 5.9E-94 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 SUPERFAMILY SSF53383 20 443 5.49E-117 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 Gene3D G3DSA:3.40.640.10 66 334 4.3E-136 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 Gene3D G3DSA:3.90.1150.10 11 441 4.3E-136 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 253 290 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 PIRSF PIRSF000521 3 139 6.3E-5 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 PIRSF PIRSF000521 110 446 2.5E-37 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 Pfam PF00202 Aminotransferase class-III 30 443 9.2E-95 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_05450 c295ff4485ca7156c7a79b4ccbfc8a50 448 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 10 447 1.3E-170 T 11-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Gene3D G3DSA:3.30.70.3380 378 489 2.2E-43 T 11-10-2018 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 184 2.6E-19 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Pfam PF00009 Elongation factor Tu GTP binding domain 13 191 7.0E-53 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Pfam PF06421 GTP-binding protein LepA C-terminus 498 604 7.6E-52 T 11-10-2018 IPR013842 GTP-binding protein LepA, C-terminal UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Gene3D G3DSA:3.30.70.2570 490 564 6.0E-35 T 11-10-2018 IPR038363 LepA, C-terminal domain superfamily UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 SUPERFAMILY SSF54980 302 380 1.01E-18 T 11-10-2018 IPR035647 EF-G domain III/V-like UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Gene3D G3DSA:2.40.30.10 196 295 7.1E-38 T 11-10-2018 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Gene3D G3DSA:3.40.50.300 10 195 2.3E-73 T 11-10-2018 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 SUPERFAMILY SSF52540 10 215 1.53E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 PRINTS PR00315 GTP-binding elongation factor signature 16 29 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Gene3D G3DSA:3.30.70.870 296 377 2.3E-36 T 11-10-2018 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Pfam PF00679 Elongation factor G C-terminus 409 496 9.4E-25 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 SMART SM00838 408 496 2.1E-4 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 SUPERFAMILY SSF54980 409 504 1.29E-26 T 11-10-2018 IPR035647 EF-G domain III/V-like UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 SUPERFAMILY SSF50447 176 298 3.53E-33 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Hamap MF_00071 Elongation factor 4 [lepA]. 1 608 313.239 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 TIGRFAM TIGR01393 lepA: elongation factor 4 13 606 0.0 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 UP12_11580 87cf20a482b14c2865e7daf844dcb5b3 612 Pfam PF03144 Elongation factor Tu domain 2 215 285 2.6E-12 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 SUPERFAMILY SSF56327 168 440 2.31E-89 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 SUPERFAMILY SSF51735 3 164 5.68E-55 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 Pfam PF02056 Family 4 glycosyl hydrolase 6 184 5.6E-67 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 Gene3D G3DSA:3.90.110.10 167 441 1.6E-95 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 Gene3D G3DSA:3.40.50.720 1 166 2.4E-59 T 11-10-2018 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 416 2.2E-47 T 11-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 11-10-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 6.9E-58 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 6.9E-58 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 6.9E-58 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 6.9E-58 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 6.9E-58 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 6.9E-58 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_03650 d07518fdb854d7ea830b3cf9dd440950 441 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 6.9E-58 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 SUPERFAMILY SSF52540 173 436 4.28E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 SUPERFAMILY SSF50249 3 168 9.59E-31 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 SMART SM00490 488 573 6.0E-20 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 Gene3D G3DSA:2.40.50.140 49 138 2.8E-9 T 11-10-2018 UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 Pfam PF17191 RecG wedge domain 10 165 2.3E-17 T 11-10-2018 IPR033454 RecG, wedge domain UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 Gene3D G3DSA:3.40.50.300 441 613 4.6E-57 T 11-10-2018 UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 Gene3D G3DSA:1.10.150.20 2 48 5.0E-5 T 11-10-2018 UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 5.9E-256 T 11-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 Pfam PF00270 DEAD/DEAH box helicase 258 415 7.3E-20 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 Gene3D G3DSA:3.40.50.300 196 434 3.8E-91 T 11-10-2018 UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 Pfam PF00271 Helicase conserved C-terminal domain 452 572 9.6E-20 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 SUPERFAMILY SSF52540 369 629 1.49E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07730 a39ccfede0dc28166bf6f270faf2c85f 682 SMART SM00487 253 442 8.9E-36 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_06715 2e170d805520ec8cedaf028f973ffeda 80 ProDom PD028055 SPLA TRANSCRIPTIONAL TRANSCRIPTION REGULATOR REGULATION 6 80 4.0E-24 T 11-10-2018 UP12_06715 2e170d805520ec8cedaf028f973ffeda 80 Pfam PF11132 Transcriptional regulator protein (SplA) 9 80 1.7E-38 T 11-10-2018 IPR022608 Transcription regulator SplA UP12_08195 0b4795adfc9c85802320a07f4978b343 339 Gene3D G3DSA:3.40.50.720 7 331 2.6E-139 T 11-10-2018 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 334 1.7E-160 T 11-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 SUPERFAMILY SSF51735 5 157 2.99E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08195 0b4795adfc9c85802320a07f4978b343 339 PIRSF PIRSF000148 4 339 1.1E-131 T 11-10-2018 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 230 244 - T 11-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 SUPERFAMILY SSF55347 129 321 2.65E-76 T 11-10-2018 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 334 38.149 T 11-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 SMART SM00859 6 121 1.8E-42 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 139 320 6.4E-62 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 120 1.0E-33 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 UP12_08195 0b4795adfc9c85802320a07f4978b343 339 Gene3D G3DSA:3.30.360.10 128 317 2.6E-139 T 11-10-2018 UP12_17895 877e6684ffad404e218f45107921b395 274 PIRSF PIRSF000513 4 267 1.1E-98 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 SUPERFAMILY SSF53613 9 261 3.1E-59 T 11-10-2018 IPR029056 Ribokinase-like UP12_17895 877e6684ffad404e218f45107921b395 274 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 12 261 33.413 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 1.7E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 119 133 1.7E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 18 25 1.7E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 62 70 1.7E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 31 52 1.7E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 88 105 1.7E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 Gene3D G3DSA:3.40.1190.20 1 269 1.9E-101 T 11-10-2018 IPR029056 Ribokinase-like UP12_17895 877e6684ffad404e218f45107921b395 274 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 10 256 2.1E-95 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17895 877e6684ffad404e218f45107921b395 274 Pfam PF02110 Hydroxyethylthiazole kinase family 10 255 3.8E-92 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_10495 58795c2ad396901bd866986b86773129 419 SUPERFAMILY SSF103473 18 414 1.15E-57 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_10495 58795c2ad396901bd866986b86773129 419 Pfam PF07690 Major Facilitator Superfamily 239 409 1.5E-11 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_10495 58795c2ad396901bd866986b86773129 419 Pfam PF07690 Major Facilitator Superfamily 37 216 4.3E-26 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_10495 58795c2ad396901bd866986b86773129 419 Gene3D G3DSA:1.20.1250.20 24 406 2.5E-45 T 11-10-2018 UP12_14735 098327a6538e01bddefe626a144e84e4 663 SMART SM00304 305 357 3.0E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14735 098327a6538e01bddefe626a144e84e4 663 Pfam PF02743 Cache domain 54 267 9.6E-26 T 11-10-2018 IPR033479 Double Cache domain 1 UP12_14735 098327a6538e01bddefe626a144e84e4 663 SUPERFAMILY SSF103190 128 195 3.53E-10 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_14735 098327a6538e01bddefe626a144e84e4 663 SUPERFAMILY SSF58104 325 661 1.11E-67 T 11-10-2018 UP12_14735 098327a6538e01bddefe626a144e84e4 663 Pfam PF00672 HAMP domain 311 354 8.1E-8 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14735 098327a6538e01bddefe626a144e84e4 663 Gene3D G3DSA:1.10.287.950 359 661 9.2E-67 T 11-10-2018 UP12_14735 098327a6538e01bddefe626a144e84e4 663 SMART SM00319 33 153 7.5E-7 T 11-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 UP12_14735 098327a6538e01bddefe626a144e84e4 663 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 433 615 1.9E-50 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_14735 098327a6538e01bddefe626a144e84e4 663 Gene3D G3DSA:3.30.450.20 60 267 1.1E-33 T 11-10-2018 UP12_14735 098327a6538e01bddefe626a144e84e4 663 Gene3D G3DSA:3.30.450.20 72 185 1.1E-33 T 11-10-2018 UP12_14735 098327a6538e01bddefe626a144e84e4 663 Gene3D G3DSA:1.10.8.500 304 356 7.0E-10 T 11-10-2018 UP12_14735 098327a6538e01bddefe626a144e84e4 663 SMART SM00283 386 661 1.8E-85 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_17805 3e209928ab137c5bb7f9dc561e052b08 205 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 14 201 2.7E-92 T 11-10-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 UP12_17805 3e209928ab137c5bb7f9dc561e052b08 205 Pfam PF00510 Cytochrome c oxidase subunit III 25 200 3.7E-16 T 11-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17805 3e209928ab137c5bb7f9dc561e052b08 205 Gene3D G3DSA:1.20.120.80 18 201 2.1E-53 T 11-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17805 3e209928ab137c5bb7f9dc561e052b08 205 SUPERFAMILY SSF81452 21 200 9.55E-54 T 11-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 SMART SM00267 365 538 8.4E-60 T 11-10-2018 IPR000160 GGDEF domain UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 Gene3D G3DSA:3.20.20.450 552 801 2.2E-98 T 11-10-2018 IPR035919 EAL domain superfamily UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 Pfam PF00563 EAL domain 555 788 1.3E-71 T 11-10-2018 IPR001633 EAL domain UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 537 1.4E-33 T 11-10-2018 IPR000160 GGDEF domain UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 Gene3D G3DSA:3.30.70.270 371 551 1.9E-55 T 11-10-2018 UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 SUPERFAMILY SSF141868 555 798 5.23E-89 T 11-10-2018 IPR035919 EAL domain superfamily UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 SUPERFAMILY SSF55785 249 363 3.93E-7 T 11-10-2018 IPR035965 PAS domain superfamily UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 SMART SM00052 548 793 5.1E-123 T 11-10-2018 IPR001633 EAL domain UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 Pfam PF00990 Diguanylate cyclase, GGDEF domain 376 533 3.3E-46 T 11-10-2018 IPR000160 GGDEF domain UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 Gene3D G3DSA:3.30.450.20 246 370 1.2E-9 T 11-10-2018 UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 Pfam PF03707 Bacterial signalling protein N terminal repeat 54 110 2.9E-15 T 11-10-2018 IPR005330 MHYT domain UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 Pfam PF03707 Bacterial signalling protein N terminal repeat 117 167 1.1E-10 T 11-10-2018 IPR005330 MHYT domain UP12_06485 27591c61c92dd4f61d4899d93aac1c4b 807 SUPERFAMILY SSF55073 381 540 3.77E-45 T 11-10-2018 IPR029787 Nucleotide cyclase UP12_10215 abe8c465e550630c5c1e151996a1d814 234 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 35.271 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UP12_10215 abe8c465e550630c5c1e151996a1d814 234 SUPERFAMILY SSF53335 3 227 7.0E-46 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_10215 abe8c465e550630c5c1e151996a1d814 234 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 7.7E-107 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UP12_10215 abe8c465e550630c5c1e151996a1d814 234 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 1.5E-134 T 11-10-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UP12_10215 abe8c465e550630c5c1e151996a1d814 234 Gene3D G3DSA:3.40.50.150 15 234 1.1E-62 T 11-10-2018 UP12_10215 abe8c465e550630c5c1e151996a1d814 234 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 141 155 - T 11-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UP12_10215 abe8c465e550630c5c1e151996a1d814 234 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 11-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 UP12_10215 abe8c465e550630c5c1e151996a1d814 234 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 2.6E-79 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 UP12_04300 56149ea652c5b681cf09f1fcb2673445 104 Gene3D G3DSA:1.10.287.880 1 50 1.0E-26 T 11-10-2018 UP12_04300 56149ea652c5b681cf09f1fcb2673445 104 Pfam PF08838 Protein of unknown function (DUF1811) 3 100 1.2E-42 T 11-10-2018 IPR014938 Protein of unknown function DUF1811 UP12_04300 56149ea652c5b681cf09f1fcb2673445 104 SUPERFAMILY SSF101697 1 103 2.22E-43 T 11-10-2018 IPR036289 Hypothetical protein YfhH UP12_04300 56149ea652c5b681cf09f1fcb2673445 104 Gene3D G3DSA:2.30.30.340 51 104 2.5E-21 T 11-10-2018 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 Gene3D G3DSA:2.60.120.180 27 228 2.5E-92 T 11-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 PRINTS PR00911 Glycosyl hydrolase family 11 signature 143 149 8.1E-18 T 11-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 PRINTS PR00911 Glycosyl hydrolase family 11 signature 191 199 8.1E-18 T 11-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 PRINTS PR00911 Glycosyl hydrolase family 11 signature 117 127 8.1E-18 T 11-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 PRINTS PR00911 Glycosyl hydrolase family 11 signature 168 177 8.1E-18 T 11-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 PRINTS PR00911 Glycosyl hydrolase family 11 signature 107 116 8.1E-18 T 11-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 PRINTS PR00911 Glycosyl hydrolase family 11 signature 163 168 8.1E-18 T 11-10-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 Pfam PF00457 Glycosyl hydrolases family 11 39 219 5.5E-66 T 11-10-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 117 127 - T 11-10-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 206 217 - T 11-10-2018 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_09355 56a91e7fe0e89098c8bc45080d7b9daa 228 SUPERFAMILY SSF49899 29 226 1.37E-81 T 11-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UP12_09765 0752cdb51d4343cce1b97bf1114a6f34 322 Gene3D G3DSA:3.40.50.300 8 148 1.5E-27 T 11-10-2018 UP12_09765 0752cdb51d4343cce1b97bf1114a6f34 322 SUPERFAMILY SSF52540 9 215 1.0E-33 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09765 0752cdb51d4343cce1b97bf1114a6f34 322 Pfam PF14532 Sigma-54 interaction domain 14 148 3.0E-16 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 UP12_09765 0752cdb51d4343cce1b97bf1114a6f34 322 Gene3D G3DSA:1.10.8.60 149 220 5.3E-13 T 11-10-2018 UP12_09765 0752cdb51d4343cce1b97bf1114a6f34 322 SMART SM00382 29 141 0.0031 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_12085 8f0330643bac1cf5bd0385e566130236 170 Pfam PF00156 Phosphoribosyl transferase domain 36 148 7.2E-15 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UP12_12085 8f0330643bac1cf5bd0385e566130236 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.897 T 11-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 UP12_12085 8f0330643bac1cf5bd0385e566130236 170 SUPERFAMILY SSF53271 2 163 7.1E-50 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_12085 8f0330643bac1cf5bd0385e566130236 170 Gene3D G3DSA:3.40.50.2020 1 170 5.5E-59 T 11-10-2018 UP12_12085 8f0330643bac1cf5bd0385e566130236 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 170 3.7E-71 T 11-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 UP12_09005 6a1ad72d67df49105ffc91ace76e2893 310 Gene3D G3DSA:1.10.3720.10 67 309 1.4E-72 T 11-10-2018 IPR035906 MetI-like superfamily UP12_09005 6a1ad72d67df49105ffc91ace76e2893 310 SUPERFAMILY SSF160964 30 74 9.68E-5 T 11-10-2018 UP12_09005 6a1ad72d67df49105ffc91ace76e2893 310 SUPERFAMILY SSF161098 71 296 8.5E-64 T 11-10-2018 IPR035906 MetI-like superfamily UP12_09005 6a1ad72d67df49105ffc91ace76e2893 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 302 1.7E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 SUPERFAMILY SSF53686 13 366 1.15E-97 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 Gene3D G3DSA:3.40.50.1100 24 327 3.4E-114 T 11-10-2018 UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 TIGRFAM TIGR02079 THD1: threonine dehydratase 14 422 6.8E-194 T 11-10-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 Gene3D G3DSA:3.40.50.1100 59 158 3.4E-114 T 11-10-2018 UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 419 1.0E-29 T 11-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 316 1.2E-70 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UP12_09760 6e8fb0a0cc5cd7db03e4c042f049d001 422 Gene3D G3DSA:3.40.1020.10 328 422 4.7E-10 T 11-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 202 4.3E-61 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 Gene3D G3DSA:2.40.30.10 340 395 2.1E-26 T 11-10-2018 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 Gene3D G3DSA:3.40.50.300 1 204 9.2E-70 T 11-10-2018 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.2E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.2E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.2E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.2E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.2E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.4E-32 T 11-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal UP12_00710 b914a1627245d3b0323202f02df59d3e 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.192 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 9.3E-233 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site UP12_00710 b914a1627245d3b0323202f02df59d3e 396 Gene3D G3DSA:2.40.30.10 207 336 1.8E-54 T 11-10-2018 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 SUPERFAMILY SSF50447 204 303 6.09E-33 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_00710 b914a1627245d3b0323202f02df59d3e 396 SUPERFAMILY SSF50465 304 396 3.74E-35 T 11-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal UP12_00710 b914a1627245d3b0323202f02df59d3e 396 SUPERFAMILY SSF52540 6 220 3.43E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00710 b914a1627245d3b0323202f02df59d3e 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 146 4.4E-16 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_00710 b914a1627245d3b0323202f02df59d3e 396 Pfam PF03144 Elongation factor Tu domain 2 226 295 2.8E-19 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 UP12_04935 8ca784d6112688f7916f8611f9c281ec 285 TIGRFAM TIGR01121 D_amino_aminoT: D-amino-acid transaminase 2 276 1.4E-129 T 11-10-2018 IPR005784 D-amino acid aminotransferase GO:0008483|GO:0030170|GO:0046416 KEGG: 00310+2.6.1.21|KEGG: 00330+2.6.1.21|KEGG: 00360+2.6.1.21|KEGG: 00472+2.6.1.21|KEGG: 00473+2.6.1.21 UP12_04935 8ca784d6112688f7916f8611f9c281ec 285 Gene3D G3DSA:3.30.470.10 3 116 2.4E-33 T 11-10-2018 UP12_04935 8ca784d6112688f7916f8611f9c281ec 285 SUPERFAMILY SSF56752 2 277 5.36E-76 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 UP12_04935 8ca784d6112688f7916f8611f9c281ec 285 Pfam PF01063 Amino-transferase class IV 29 250 3.8E-46 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 UP12_04935 8ca784d6112688f7916f8611f9c281ec 285 ProSitePatterns PS00770 Aminotransferases class-IV signature. 176 205 - T 11-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 UP12_04935 8ca784d6112688f7916f8611f9c281ec 285 Gene3D G3DSA:3.20.10.10 119 282 1.7E-56 T 11-10-2018 UP12_19045 bd7f5fd724591fb6c243988a4244d9a0 285 Gene3D G3DSA:3.90.640.20 186 285 1.1E-42 T 11-10-2018 IPR037126 PdaC/RsiV-like superfamily UP12_19045 bd7f5fd724591fb6c243988a4244d9a0 285 Pfam PF13739 Domain of unknown function (DUF4163) 85 158 1.4E-8 T 11-10-2018 IPR025303 Deacetylase PdaC UP12_19045 bd7f5fd724591fb6c243988a4244d9a0 285 Gene3D G3DSA:3.30.565.40 75 185 2.9E-32 T 11-10-2018 UP12_19045 bd7f5fd724591fb6c243988a4244d9a0 285 Pfam PF11738 Protein of unknown function (DUF3298) 190 272 1.2E-20 T 11-10-2018 IPR021729 Domain of unknown function DUF3298 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 SMART SM00436 104 192 1.5E-52 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Gene3D G3DSA:3.40.50.140 1 134 1.1E-53 T 11-10-2018 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Pfam PF01131 DNA topoisomerase 128 547 3.0E-139 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 642 57.105 T 11-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 4.1E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 4.1E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 4.1E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 4.1E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 4.1E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Gene3D G3DSA:2.70.20.10 184 457 3.6E-171 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Gene3D G3DSA:3.30.65.10 559 618 1.7E-14 T 11-10-2018 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 SMART SM00493 3 103 1.6E-31 T 11-10-2018 IPR006171 TOPRIM domain UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Gene3D G3DSA:1.10.460.10 135 550 3.6E-171 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 5.6E-274 T 11-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 SUPERFAMILY SSF57783 569 612 1.33E-14 T 11-10-2018 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Gene3D G3DSA:1.10.290.10 250 385 3.6E-171 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Pfam PF01751 Toprim domain 5 113 1.6E-29 T 11-10-2018 IPR006171 TOPRIM domain UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 613 2.0E-16 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 616 655 7.7E-13 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 658 689 0.008 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 SMART SM00437 242 510 1.2E-137 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 UP12_07850 935156b06ca334c52d9c767712ae6b80 691 SUPERFAMILY SSF56712 4 589 3.14E-203 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain UP12_17680 8efb6a693e155be681f4260cd5ef52e2 470 Gene3D G3DSA:3.40.50.2000 286 394 1.4E-5 T 11-10-2018 UP12_17680 8efb6a693e155be681f4260cd5ef52e2 470 Gene3D G3DSA:3.40.50.2000 251 285 1.4E-5 T 11-10-2018 UP12_17680 8efb6a693e155be681f4260cd5ef52e2 470 Pfam PF05159 Capsule polysaccharide biosynthesis protein 309 391 8.3E-7 T 11-10-2018 IPR007833 Capsule polysaccharide biosynthesis GO:0000271|GO:0015774 UP12_17680 8efb6a693e155be681f4260cd5ef52e2 470 SUPERFAMILY SSF53756 218 460 7.85E-21 T 11-10-2018 UP12_06045 7e816562b229c8d0871216d0e12f887d 384 Gene3D G3DSA:1.20.1250.20 2 187 2.0E-16 T 11-10-2018 UP12_06045 7e816562b229c8d0871216d0e12f887d 384 Pfam PF07690 Major Facilitator Superfamily 23 179 7.0E-11 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_06045 7e816562b229c8d0871216d0e12f887d 384 Gene3D G3DSA:1.20.1250.20 189 379 1.2E-15 T 11-10-2018 UP12_06045 7e816562b229c8d0871216d0e12f887d 384 SUPERFAMILY SSF103473 4 378 6.28E-43 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_15740 c3e96db630007281063d9f31cd9b3b1d 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_15740 c3e96db630007281063d9f31cd9b3b1d 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 58 1.5E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_15740 c3e96db630007281063d9f31cd9b3b1d 202 SUPERFAMILY SSF46689 4 80 4.29E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_15740 c3e96db630007281063d9f31cd9b3b1d 202 SUPERFAMILY SSF48498 80 197 5.44E-27 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_15740 c3e96db630007281063d9f31cd9b3b1d 202 Gene3D G3DSA:1.10.357.10 5 201 2.8E-51 T 11-10-2018 UP12_15740 c3e96db630007281063d9f31cd9b3b1d 202 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 195 1.0E-24 T 11-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal UP12_07640 08e6ab8211ba5a89c1ad2e3f31597da8 67 Pfam PF01192 RNA polymerase Rpb6 9 61 1.5E-11 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UP12_07640 08e6ab8211ba5a89c1ad2e3f31597da8 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 14.304 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_07640 08e6ab8211ba5a89c1ad2e3f31597da8 67 SMART SM01409 8 61 6.3E-12 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UP12_07640 08e6ab8211ba5a89c1ad2e3f31597da8 67 SUPERFAMILY SSF63562 1 66 1.92E-21 T 11-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UP12_07640 08e6ab8211ba5a89c1ad2e3f31597da8 67 Gene3D G3DSA:3.90.940.10 1 67 8.0E-17 T 11-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 UP12_07640 08e6ab8211ba5a89c1ad2e3f31597da8 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 7.6E-25 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_01010 897f7f207f635be136c38fdd0ba29230 457 Pfam PF00367 phosphotransferase system, EIIB 12 44 1.3E-12 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_01010 897f7f207f635be136c38fdd0ba29230 457 Pfam PF02378 Phosphotransferase system, EIIC 120 389 8.8E-39 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_01010 897f7f207f635be136c38fdd0ba29230 457 SUPERFAMILY SSF55604 10 84 1.02E-16 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_01010 897f7f207f635be136c38fdd0ba29230 457 Gene3D G3DSA:3.30.1360.60 2 81 1.4E-23 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_09825 89f3ef1e8225529518a338f198236413 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 11-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 UP12_09825 89f3ef1e8225529518a338f198236413 160 Gene3D G3DSA:3.40.30.10 1 160 6.2E-71 T 11-10-2018 UP12_09825 89f3ef1e8225529518a338f198236413 160 SUPERFAMILY SSF52833 1 158 1.6E-62 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_09825 89f3ef1e8225529518a338f198236413 160 PIRSF PIRSF000303 1 160 1.2E-68 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 UP12_09825 89f3ef1e8225529518a338f198236413 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 11-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 UP12_09825 89f3ef1e8225529518a338f198236413 160 Pfam PF00255 Glutathione peroxidase 3 109 1.2E-42 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 UP12_09825 89f3ef1e8225529518a338f198236413 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 5.9E-20 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 UP12_09825 89f3ef1e8225529518a338f198236413 160 PRINTS PR01011 Glutathione peroxidase family signature 56 72 5.9E-20 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 UP12_09825 89f3ef1e8225529518a338f198236413 160 PRINTS PR01011 Glutathione peroxidase family signature 21 38 5.9E-20 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 UP12_01385 c11ee9e433f38c65342566d8d4110188 473 Pfam PF00232 Glycosyl hydrolase family 1 8 468 2.4E-157 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_01385 c11ee9e433f38c65342566d8d4110188 473 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 11-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UP12_01385 c11ee9e433f38c65342566d8d4110188 473 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 367 375 - T 11-10-2018 IPR018120 Glycoside hydrolase family 1, active site UP12_01385 c11ee9e433f38c65342566d8d4110188 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 399 4.9E-16 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_01385 c11ee9e433f38c65342566d8d4110188 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 375 4.9E-16 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_01385 c11ee9e433f38c65342566d8d4110188 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 409 426 4.9E-16 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_01385 c11ee9e433f38c65342566d8d4110188 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 4.9E-16 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_01385 c11ee9e433f38c65342566d8d4110188 473 PRINTS PR00131 Glycosyl hydrolase family 1 signature 433 445 4.9E-16 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_01385 c11ee9e433f38c65342566d8d4110188 473 SUPERFAMILY SSF51445 7 469 4.49E-166 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_01385 c11ee9e433f38c65342566d8d4110188 473 Gene3D G3DSA:3.20.20.80 2 471 1.1E-163 T 11-10-2018 UP12_11635 5d107ba969b66664c0d4bc34c89ae127 247 Gene3D G3DSA:2.20.25.110 140 201 5.4E-83 T 11-10-2018 UP12_11635 5d107ba969b66664c0d4bc34c89ae127 247 SUPERFAMILY SSF53335 3 243 1.66E-53 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_11635 5d107ba969b66664c0d4bc34c89ae127 247 Pfam PF13649 Methyltransferase domain 36 132 4.8E-21 T 11-10-2018 UP12_11635 5d107ba969b66664c0d4bc34c89ae127 247 Gene3D G3DSA:3.40.50.150 6 239 5.4E-83 T 11-10-2018 UP12_06630 06cf5c33b4f684acc51acffaab9ce33b 146 SUPERFAMILY SSF55620 12 139 1.45E-31 T 11-10-2018 UP12_06630 06cf5c33b4f684acc51acffaab9ce33b 146 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 110 1.4E-27 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 UP12_06630 06cf5c33b4f684acc51acffaab9ce33b 146 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 138 6.9E-28 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 UP12_06630 06cf5c33b4f684acc51acffaab9ce33b 146 PIRSF PIRSF006113 13 140 5.2E-19 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 UP12_06630 06cf5c33b4f684acc51acffaab9ce33b 146 Gene3D G3DSA:3.30.479.10 13 140 1.4E-27 T 11-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 SUPERFAMILY SSF46785 9 80 2.86E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 Pfam PF02629 CoA binding domain 83 181 4.7E-29 T 11-10-2018 IPR003781 CoA-binding GO:0048037 UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 212 39.517 T 11-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 SMART SM00881 81 183 2.2E-20 T 11-10-2018 IPR003781 CoA-binding GO:0048037 UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 Gene3D G3DSA:1.10.10.10 1 82 1.7E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 Gene3D G3DSA:3.40.50.720 83 217 1.7E-48 T 11-10-2018 UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 1.5E-19 T 11-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 UP12_03155 5908caa97a4d068ce4a93937c4d282b3 217 SUPERFAMILY SSF51735 83 210 1.97E-27 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_05785 d8c44981407b914a1543b053268c0508 209 Pfam PF04607 Region found in RelA / SpoT proteins 45 163 4.5E-38 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 UP12_05785 d8c44981407b914a1543b053268c0508 209 SMART SM00954 45 165 1.4E-42 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 UP12_05785 d8c44981407b914a1543b053268c0508 209 Gene3D G3DSA:3.30.460.10 1 147 1.4E-56 T 11-10-2018 UP12_05785 d8c44981407b914a1543b053268c0508 209 Gene3D G3DSA:1.10.287.860 148 209 2.4E-28 T 11-10-2018 UP12_05785 d8c44981407b914a1543b053268c0508 209 SUPERFAMILY SSF81301 5 200 2.29E-59 T 11-10-2018 UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 4.3E-21 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 SMART SM00345 14 73 3.3E-22 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 SMART SM00866 95 233 1.9E-24 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 3.8E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 3.8E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 SUPERFAMILY SSF64288 62 239 2.51E-36 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 SUPERFAMILY SSF46785 2 88 5.0E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 Gene3D G3DSA:3.40.1410.10 77 238 5.1E-28 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 Gene3D G3DSA:1.10.10.10 2 74 3.6E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08230 5a1cf0c47216969cce48bb9485f7587d 241 Pfam PF07702 UTRA domain 97 232 1.8E-28 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 Gene3D G3DSA:3.40.50.720 3 89 1.7E-21 T 11-10-2018 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 Gene3D G3DSA:3.90.190.20 293 431 1.5E-39 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 SUPERFAMILY SSF51984 4 88 8.5E-22 T 11-10-2018 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 SUPERFAMILY SSF53244 294 427 5.13E-37 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 Pfam PF02875 Mur ligase family, glutamate ligase domain 295 378 5.7E-18 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 Gene3D G3DSA:3.40.1190.10 91 292 4.2E-53 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 429 2.0E-141 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 SUPERFAMILY SSF53623 87 293 5.49E-59 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 Pfam PF01225 Mur ligase family, catalytic domain 4 101 5.0E-24 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 432 34.67 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_13440 e099cd85f9752a1b89b5ff1eb92f1b63 432 Pfam PF08245 Mur ligase middle domain 106 275 3.1E-26 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UP12_04960 75f8f999dc1c77069d5e535d8dbff359 67 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 23 32 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 UP12_04960 75f8f999dc1c77069d5e535d8dbff359 67 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 41 55 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 UP12_04960 75f8f999dc1c77069d5e535d8dbff359 67 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 8 62 3.9E-22 T 11-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 UP12_04960 75f8f999dc1c77069d5e535d8dbff359 67 Gene3D G3DSA:1.10.8.910 8 67 2.0E-30 T 11-10-2018 IPR038300 SASP, alpha/beta-type superfamily UP12_10415 3220d193198265a7ba564fdbd2539bb2 176 SUPERFAMILY SSF52833 35 167 1.14E-42 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_10415 3220d193198265a7ba564fdbd2539bb2 176 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UP12_10415 3220d193198265a7ba564fdbd2539bb2 176 Gene3D G3DSA:3.40.30.10 36 174 3.0E-46 T 11-10-2018 UP12_10415 3220d193198265a7ba564fdbd2539bb2 176 Pfam PF00578 AhpC/TSA family 38 152 3.1E-34 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 SMART SM01274 64 245 3.2E-95 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 Gene3D G3DSA:3.40.50.10380 1 252 3.2E-103 T 11-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 Pfam PF03949 Malic enzyme, NAD binding domain 255 516 2.6E-104 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PRINTS PR00072 Malic enzyme signature 70 94 4.2E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PRINTS PR00072 Malic enzyme signature 226 244 4.2E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PRINTS PR00072 Malic enzyme signature 282 298 4.2E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PRINTS PR00072 Malic enzyme signature 394 410 4.2E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PRINTS PR00072 Malic enzyme signature 251 267 4.2E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PRINTS PR00072 Malic enzyme signature 167 189 4.2E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PRINTS PR00072 Malic enzyme signature 131 160 4.2E-69 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 SUPERFAMILY SSF53223 2 254 1.51E-100 T 11-10-2018 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 Pfam PF00390 Malic enzyme, N-terminal domain 64 245 1.8E-72 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 SUPERFAMILY SSF51735 255 544 2.72E-91 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 PIRSF PIRSF000106 1 547 9.3E-221 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 ProSitePatterns PS00331 Malic enzymes signature. 251 267 - T 11-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 Gene3D G3DSA:3.40.50.720 253 547 2.5E-108 T 11-10-2018 UP12_13485 5669327ee4ae57ae277b57b98e1f41bf 547 SMART SM00919 255 516 2.4E-123 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UP12_02280 9446d784204b5a95fb4d2d37afc568f1 211 Pfam PF02525 Flavodoxin-like fold 3 206 5.0E-48 T 11-10-2018 IPR003680 Flavodoxin-like fold UP12_02280 9446d784204b5a95fb4d2d37afc568f1 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 211 29.061 T 11-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 UP12_02280 9446d784204b5a95fb4d2d37afc568f1 211 SUPERFAMILY SSF52218 1 210 1.56E-54 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_02280 9446d784204b5a95fb4d2d37afc568f1 211 Gene3D G3DSA:3.40.50.360 1 211 1.2E-62 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_03765 e47f7baa7e2e502ea8d483526bfd5878 159 SUPERFAMILY SSF49764 53 149 1.4E-16 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_03765 e47f7baa7e2e502ea8d483526bfd5878 159 Gene3D G3DSA:2.60.40.790 42 152 8.4E-18 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_03765 e47f7baa7e2e502ea8d483526bfd5878 159 Pfam PF00011 Hsp20/alpha crystallin family 60 150 2.0E-9 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 SUPERFAMILY SSF47413 3 50 1.76E-11 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.3E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.3E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 11-10-2018 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 Gene3D G3DSA:3.40.50.2300 81 331 4.3E-56 T 11-10-2018 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 Gene3D G3DSA:3.40.50.2300 165 300 4.3E-56 T 11-10-2018 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 SMART SM00354 1 78 7.6E-16 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 SUPERFAMILY SSF53822 66 333 2.16E-53 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 Gene3D G3DSA:1.10.260.40 1 47 1.7E-16 T 11-10-2018 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 49 4.2E-16 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_09015 c628f41d509cac2d3701fe65899bba1b 346 Pfam PF13377 Periplasmic binding protein-like domain 173 339 2.0E-36 T 11-10-2018 UP12_03685 81d4ded23bd36688d82796ebd286e312 243 Pfam PF01380 SIS domain 107 215 6.7E-16 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_03685 81d4ded23bd36688d82796ebd286e312 243 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 72 1.7E-14 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_03685 81d4ded23bd36688d82796ebd286e312 243 Gene3D G3DSA:3.40.50.10490 90 243 6.7E-31 T 11-10-2018 UP12_03685 81d4ded23bd36688d82796ebd286e312 243 Gene3D G3DSA:1.10.10.10 4 89 1.6E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03685 81d4ded23bd36688d82796ebd286e312 243 SUPERFAMILY SSF53697 83 236 6.01E-30 T 11-10-2018 UP12_03685 81d4ded23bd36688d82796ebd286e312 243 SUPERFAMILY SSF46689 5 73 5.38E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 SUPERFAMILY SSF89095 295 400 6.45E-36 T 11-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 39.189 T 11-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 SMART SM00845 326 473 8.5E-80 T 11-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 Gene3D G3DSA:1.10.150.380 298 411 7.5E-39 T 11-10-2018 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 473 1.3E-180 T 11-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 SUPERFAMILY SSF55931 4 294 7.19E-121 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 Gene3D G3DSA:1.10.10.410 413 476 3.0E-26 T 11-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 11-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 Pfam PF02637 GatB domain 326 473 4.0E-56 T 11-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 UP12_03585 f2fe14fd6407e319a4dbe61d5a69d215 476 Pfam PF02934 GatB/GatE catalytic domain 5 286 2.3E-111 T 11-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 UP12_07690 a60220258d2c8d96541214a6896b3346 216 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 214 2.2E-93 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UP12_07690 a60220258d2c8d96541214a6896b3346 216 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 201 3.8E-89 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UP12_07690 a60220258d2c8d96541214a6896b3346 216 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UP12_07690 a60220258d2c8d96541214a6896b3346 216 SUPERFAMILY SSF51366 2 214 1.77E-75 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_07690 a60220258d2c8d96541214a6896b3346 216 PIRSF PIRSF001461 1 216 8.2E-96 T 11-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UP12_07690 a60220258d2c8d96541214a6896b3346 216 Gene3D G3DSA:3.20.20.70 1 216 3.4E-90 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_15695 02d7e37121904a8933f4adc5fcbcd7ef 671 Pfam PF00999 Sodium/hydrogen exchanger family 7 412 4.4E-66 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UP12_15695 02d7e37121904a8933f4adc5fcbcd7ef 671 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 10 519 7.2E-102 T 11-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 UP12_10325 5f91532c6b087393faaa5849810922b4 424 Gene3D G3DSA:1.10.8.1210 20 352 3.8E-181 T 11-10-2018 UP12_10325 5f91532c6b087393faaa5849810922b4 424 PIRSF PIRSF000185 9 424 8.5E-172 T 11-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 UP12_10325 5f91532c6b087393faaa5849810922b4 424 SUPERFAMILY SSF53223 16 193 1.76E-65 T 11-10-2018 UP12_10325 5f91532c6b087393faaa5849810922b4 424 Gene3D G3DSA:3.40.50.720 198 351 3.8E-181 T 11-10-2018 UP12_10325 5f91532c6b087393faaa5849810922b4 424 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 110 123 - T 11-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10325 5f91532c6b087393faaa5849810922b4 424 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 191 422 9.4E-78 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10325 5f91532c6b087393faaa5849810922b4 424 Gene3D G3DSA:3.40.50.10860 43 178 3.8E-181 T 11-10-2018 UP12_10325 5f91532c6b087393faaa5849810922b4 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 224 244 1.6E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10325 5f91532c6b087393faaa5849810922b4 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 182 204 1.6E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10325 5f91532c6b087393faaa5849810922b4 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 102 116 1.6E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10325 5f91532c6b087393faaa5849810922b4 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 350 361 1.6E-30 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10325 5f91532c6b087393faaa5849810922b4 424 Gene3D G3DSA:1.10.8.1210 378 424 5.2E-17 T 11-10-2018 UP12_10325 5f91532c6b087393faaa5849810922b4 424 SUPERFAMILY SSF51735 191 423 5.66E-78 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10325 5f91532c6b087393faaa5849810922b4 424 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 47 173 3.2E-54 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10325 5f91532c6b087393faaa5849810922b4 424 SMART SM00839 193 422 3.4E-95 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_12800 2519ced88c6c8fc744d92c4d997d0f34 376 SUPERFAMILY SSF54506 2 166 1.57E-60 T 11-10-2018 UP12_12800 2519ced88c6c8fc744d92c4d997d0f34 376 Gene3D G3DSA:3.10.310.10 4 361 7.4E-134 T 11-10-2018 UP12_12800 2519ced88c6c8fc744d92c4d997d0f34 376 SUPERFAMILY SSF54506 170 366 2.12E-52 T 11-10-2018 UP12_12800 2519ced88c6c8fc744d92c4d997d0f34 376 Pfam PF04303 PrpF protein 1 363 2.4E-134 T 11-10-2018 IPR007400 PrpF protein UP12_12800 2519ced88c6c8fc744d92c4d997d0f34 376 Gene3D G3DSA:3.10.310.10 166 347 7.4E-134 T 11-10-2018 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 Gene3D G3DSA:3.30.860.10 1 92 1.3E-39 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.0E-23 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.0E-23 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.0E-23 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 Pfam PF00203 Ribosomal protein S19 3 83 1.4E-35 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 11-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 PIRSF PIRSF002144 1 92 2.5E-31 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 SUPERFAMILY SSF54570 3 84 7.85E-35 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 3.1E-47 T 11-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 UP12_00745 e5a5e56a3c6a5cd31d354cf3a1de1e34 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.188 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_17580 65778e2a40d75e36e79ef797290f0c4a 323 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 319 1.8E-130 T 11-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 UP12_17580 65778e2a40d75e36e79ef797290f0c4a 323 SUPERFAMILY SSF53659 4 322 3.0E-92 T 11-10-2018 UP12_17580 65778e2a40d75e36e79ef797290f0c4a 323 Gene3D G3DSA:3.40.50.10950 18 319 7.5E-135 T 11-10-2018 UP12_17580 65778e2a40d75e36e79ef797290f0c4a 323 PIRSF PIRSF000428 2 323 4.0E-110 T 11-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 UP12_17580 65778e2a40d75e36e79ef797290f0c4a 323 Gene3D G3DSA:3.40.50.10750 142 295 7.5E-135 T 11-10-2018 UP12_17580 65778e2a40d75e36e79ef797290f0c4a 323 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 1.6E-132 T 11-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 327 42.088 T 11-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 326 3.7E-122 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 141 162 8.8E-29 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 8.8E-29 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 8.8E-29 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 194 204 8.8E-29 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 Gene3D G3DSA:1.10.240.10 185 295 3.6E-137 T 11-10-2018 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 Pfam PF00579 tRNA synthetases class I (W and Y) 5 282 1.6E-80 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 SUPERFAMILY SSF52374 5 326 4.13E-96 T 11-10-2018 UP12_05685 eaa07fdbcd4d52e97028cc4639b62644 331 Gene3D G3DSA:3.40.50.620 6 325 3.6E-137 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_17465 bd42cbc42e12c860a5904f951d327705 689 Pfam PF00905 Penicillin binding protein transpeptidase domain 331 575 3.0E-29 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_17465 bd42cbc42e12c860a5904f951d327705 689 Pfam PF00912 Transglycosylase 71 239 1.8E-64 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_17465 bd42cbc42e12c860a5904f951d327705 689 SUPERFAMILY SSF56601 220 662 1.5E-113 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_17465 bd42cbc42e12c860a5904f951d327705 689 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 74 613 4.7E-179 T 11-10-2018 UP12_17465 bd42cbc42e12c860a5904f951d327705 689 Gene3D G3DSA:3.40.710.10 262 670 1.7E-111 T 11-10-2018 UP12_17465 bd42cbc42e12c860a5904f951d327705 689 Gene3D G3DSA:1.10.3810.10 66 261 6.6E-77 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_17465 bd42cbc42e12c860a5904f951d327705 689 SUPERFAMILY SSF53955 51 265 2.08E-76 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_09060 eb4f645a8005c0374b028065c2adf6fe 289 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 284 2.0E-91 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_09060 eb4f645a8005c0374b028065c2adf6fe 289 PIRSF PIRSF001359 1 284 3.4E-99 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_09060 eb4f645a8005c0374b028065c2adf6fe 289 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 283 4.6E-94 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_09060 eb4f645a8005c0374b028065c2adf6fe 289 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 84 - T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_09060 eb4f645a8005c0374b028065c2adf6fe 289 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 UP12_09060 eb4f645a8005c0374b028065c2adf6fe 289 Gene3D G3DSA:3.20.20.70 3 284 4.4E-102 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_09060 eb4f645a8005c0374b028065c2adf6fe 289 SUPERFAMILY SSF51569 1 284 1.67E-93 T 11-10-2018 UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 SMART SM01091 354 431 3.3E-19 T 11-10-2018 IPR005170 Transporter-associated domain UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 Gene3D G3DSA:3.10.580.10 195 348 1.2E-47 T 11-10-2018 UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 Pfam PF03471 Transporter associated domain 355 430 3.5E-16 T 11-10-2018 IPR005170 Transporter-associated domain UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 Pfam PF01595 Domain of unknown function DUF21 7 201 7.7E-49 T 11-10-2018 IPR002550 CNNM, transmembrane domain UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 SUPERFAMILY SSF54631 204 341 3.92E-28 T 11-10-2018 UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 SUPERFAMILY SSF56176 352 436 2.73E-15 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 Pfam PF00571 CBS domain 290 338 1.7E-4 T 11-10-2018 IPR000644 CBS domain UP12_04885 14b8719afc9636789b8b6ec1ccf7d006 443 Gene3D G3DSA:3.30.465.10 349 439 3.8E-14 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UP12_17345 c807a10cbd72eae635ad2ffc9917f728 179 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 14 81 5.1E-14 T 11-10-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 UP12_17345 c807a10cbd72eae635ad2ffc9917f728 179 Gene3D G3DSA:1.10.10.1250 2 82 7.0E-32 T 11-10-2018 IPR038087 DNA-directed RNA polymerase subunit delta domain superfamily UP12_17345 c807a10cbd72eae635ad2ffc9917f728 179 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 179 14.985 T 11-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 UP12_17345 c807a10cbd72eae635ad2ffc9917f728 179 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 12 93 2.9E-34 T 11-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 UP12_12310 a475730964afc52905702c30f52d846e 434 Gene3D G3DSA:3.90.190.20 303 433 4.9E-29 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_12310 a475730964afc52905702c30f52d846e 434 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 46 69 - T 11-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 UP12_12310 a475730964afc52905702c30f52d846e 434 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 380 5.0E-9 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UP12_12310 a475730964afc52905702c30f52d846e 434 Gene3D G3DSA:3.40.1190.10 5 302 3.5E-99 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_12310 a475730964afc52905702c30f52d846e 434 SUPERFAMILY SSF53244 303 430 3.11E-23 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 UP12_12310 a475730964afc52905702c30f52d846e 434 Pfam PF08245 Mur ligase middle domain 48 275 2.0E-13 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UP12_12310 a475730964afc52905702c30f52d846e 434 SUPERFAMILY SSF53623 5 301 2.86E-92 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 UP12_12310 a475730964afc52905702c30f52d846e 434 PIRSF PIRSF001563 1 434 1.1E-148 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 UP12_12310 a475730964afc52905702c30f52d846e 434 TIGRFAM TIGR01499 folC: bifunctional protein FolC 26 430 2.0E-126 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 UP12_09170 45439797ed492cdde5c5dee9fb356530 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 11-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 UP12_09170 45439797ed492cdde5c5dee9fb356530 250 Pfam PF00455 DeoR C terminal sensor domain 74 229 1.7E-44 T 11-10-2018 IPR014036 DeoR C-terminal sensor domain UP12_09170 45439797ed492cdde5c5dee9fb356530 250 SUPERFAMILY SSF100950 73 231 2.83E-29 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_09170 45439797ed492cdde5c5dee9fb356530 250 SMART SM01134 71 231 2.9E-54 T 11-10-2018 UP12_09170 45439797ed492cdde5c5dee9fb356530 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 62 1.4E-18 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_09170 45439797ed492cdde5c5dee9fb356530 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 8.1E-7 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_09170 45439797ed492cdde5c5dee9fb356530 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 8.1E-7 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_09170 45439797ed492cdde5c5dee9fb356530 250 Gene3D G3DSA:1.10.10.10 1 54 3.0E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09170 45439797ed492cdde5c5dee9fb356530 250 SUPERFAMILY SSF46785 4 59 3.29E-10 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09170 45439797ed492cdde5c5dee9fb356530 250 SMART SM00420 6 58 2.1E-19 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 PRINTS PR00171 Sugar transporter signature 101 120 9.7E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 PRINTS PR00171 Sugar transporter signature 18 28 9.7E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 PRINTS PR00171 Sugar transporter signature 254 264 9.7E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 PRINTS PR00171 Sugar transporter signature 366 378 9.7E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 PRINTS PR00171 Sugar transporter signature 343 364 9.7E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 SUPERFAMILY SSF103473 8 439 1.05E-73 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 Gene3D G3DSA:1.20.1250.20 4 440 4.2E-118 T 11-10-2018 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 9 438 1.2E-105 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_11745 fb901e45f74259bc8052ccd5e2771d4b 446 Pfam PF00083 Sugar (and other) transporter 13 441 1.4E-108 T 11-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 Gene3D G3DSA:3.30.479.20 56 147 3.6E-25 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 SUPERFAMILY SSF54713 55 143 4.97E-23 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 293 2.3E-125 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 Gene3D G3DSA:1.10.286.20 199 236 1.7E-19 T 11-10-2018 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 SUPERFAMILY SSF46934 3 54 1.36E-20 T 11-10-2018 IPR009060 UBA-like superfamily GO:0005515 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 Pfam PF00889 Elongation factor TS 70 274 9.3E-77 T 11-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 Gene3D G3DSA:1.10.8.10 1 55 1.2E-27 T 11-10-2018 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 82.804 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 SUPERFAMILY SSF54713 152 292 1.19E-52 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 UP12_08045 3df3bc7ab85b89f9332d75b1d4197949 293 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-22 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 SUPERFAMILY SSF53850 88 295 4.97E-39 T 11-10-2018 UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 Gene3D G3DSA:1.10.10.10 1 84 3.5E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 Pfam PF03466 LysR substrate binding domain 89 291 7.2E-44 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 SUPERFAMILY SSF46785 1 84 1.48E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09300 6e4b1d3f6b1fa65dd218be377ffa852e 300 Gene3D G3DSA:3.40.190.290 90 298 1.3E-51 T 11-10-2018 UP12_06145 d2912deb8c5715948ad5f667295a5d25 207 Gene3D G3DSA:3.40.630.100 2 207 7.7E-63 T 11-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily UP12_06145 d2912deb8c5715948ad5f667295a5d25 207 Pfam PF05908 Poly-gamma-glutamate hydrolase 8 197 7.2E-72 T 11-10-2018 IPR008585 Poly-gamma-glutamate hydrolase UP12_16845 ac989a364087c48d5d0a23f14a6623e6 300 Gene3D G3DSA:3.40.50.1000 10 282 5.1E-77 T 11-10-2018 IPR023214 HAD superfamily UP12_16845 ac989a364087c48d5d0a23f14a6623e6 300 Pfam PF08282 haloacid dehalogenase-like hydrolase 12 285 6.7E-60 T 11-10-2018 UP12_16845 ac989a364087c48d5d0a23f14a6623e6 300 Gene3D G3DSA:3.30.1240.10 87 214 5.1E-77 T 11-10-2018 UP12_16845 ac989a364087c48d5d0a23f14a6623e6 300 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 11 258 7.4E-32 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_16845 ac989a364087c48d5d0a23f14a6623e6 300 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 11 285 9.1E-54 T 11-10-2018 IPR000150 Cof family GO:0016787 UP12_16845 ac989a364087c48d5d0a23f14a6623e6 300 SUPERFAMILY SSF56784 7 287 1.65E-64 T 11-10-2018 IPR036412 HAD-like superfamily UP12_05520 5cb76823231d0c496fa9af8522c1f401 280 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 9 215 8.9E-61 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_05520 5cb76823231d0c496fa9af8522c1f401 280 PIRSF PIRSF006483 3 280 1.5E-98 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_05520 5cb76823231d0c496fa9af8522c1f401 280 Gene3D G3DSA:3.30.70.120 192 268 2.0E-20 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_05520 5cb76823231d0c496fa9af8522c1f401 280 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 221 275 5.1E-19 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 UP12_02265 14994405eafc6318a3d0acafe446d975 248 Gene3D G3DSA:2.40.100.10 108 247 2.1E-60 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily UP12_02265 14994405eafc6318a3d0acafe446d975 248 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 11 224 1.6E-73 T 11-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D UP12_02265 14994405eafc6318a3d0acafe446d975 248 SUPERFAMILY SSF160467 11 115 1.02E-14 T 11-10-2018 UP12_02265 14994405eafc6318a3d0acafe446d975 248 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 15 233 1.2E-78 T 11-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 UP12_02265 14994405eafc6318a3d0acafe446d975 248 Gene3D G3DSA:3.30.1360.40 5 106 4.9E-27 T 11-10-2018 UP12_02265 14994405eafc6318a3d0acafe446d975 248 SMART SM00796 10 224 9.4E-96 T 11-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D UP12_02265 14994405eafc6318a3d0acafe446d975 248 SUPERFAMILY SSF50891 111 240 1.63E-48 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 154 164 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 Pfam PF00082 Subtilase family 113 356 1.1E-54 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 309 319 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 Gene3D G3DSA:3.30.70.80 16 92 7.4E-12 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 SUPERFAMILY SSF52743 93 364 9.3E-93 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 Gene3D G3DSA:3.40.50.200 93 365 9.2E-105 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 SUPERFAMILY SSF54897 24 89 2.83E-9 T 11-10-2018 UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 118 129 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 PRINTS PR00723 Subtilisin serine protease family (S8) signature 308 324 5.6E-21 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 PRINTS PR00723 Subtilisin serine protease family (S8) signature 150 163 5.6E-21 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_10600 0ca35ece3b7efd2786a2bfdc8fac6d40 365 PRINTS PR00723 Subtilisin serine protease family (S8) signature 113 132 5.6E-21 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_05420 bd9b08ad449adc390a726f192151ff12 458 PIRSF PIRSF006603 14 458 5.8E-84 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_05420 bd9b08ad449adc390a726f192151ff12 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 427 9.8E-62 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_05420 bd9b08ad449adc390a726f192151ff12 458 Pfam PF01554 MatE 28 188 7.5E-33 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_05420 bd9b08ad449adc390a726f192151ff12 458 Pfam PF01554 MatE 253 414 1.9E-32 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 ProSitePatterns PS00760 Signal peptidases I lysine active site. 87 99 - T 11-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 ProSitePatterns PS00501 Signal peptidases I serine active site. 43 50 - T 11-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 34 50 4.3E-25 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 85 97 4.3E-25 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 139 158 4.3E-25 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 Gene3D G3DSA:2.10.109.10 64 187 4.1E-37 T 11-10-2018 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 SUPERFAMILY SSF51306 32 186 9.24E-49 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 Pfam PF00717 Peptidase S24-like 41 109 5.7E-19 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 ProSitePatterns PS00761 Signal peptidases I signature 3. 144 157 - T 11-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 UP12_04595 35aa5eadce55571ec0357023afb6cb28 188 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 17 181 3.7E-54 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_12775 c6c6a180dd3e6a85342ce1a2fa251dae 142 Pfam PF01381 Helix-turn-helix 13 70 1.4E-13 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_12775 c6c6a180dd3e6a85342ce1a2fa251dae 142 SUPERFAMILY SSF47413 7 74 7.32E-14 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_12775 c6c6a180dd3e6a85342ce1a2fa251dae 142 SMART SM00530 12 70 1.7E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_12775 c6c6a180dd3e6a85342ce1a2fa251dae 142 Gene3D G3DSA:1.10.260.40 8 133 5.6E-18 T 11-10-2018 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 Gene3D G3DSA:3.90.180.10 21 337 1.9E-117 T 11-10-2018 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 SUPERFAMILY SSF51735 146 306 5.73E-37 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 Gene3D G3DSA:3.40.50.720 157 291 1.9E-117 T 11-10-2018 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 137 7.1E-34 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 SMART SM00829 16 344 5.6E-6 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 Pfam PF00107 Zinc-binding dehydrogenase 178 307 3.1E-30 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 345 2.3E-161 T 11-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 UP12_08325 8c8ddebde545840668ab6b180c2853cc 354 SUPERFAMILY SSF50129 4 177 7.76E-51 T 11-10-2018 IPR011032 GroES-like superfamily UP12_11965 c4390b2b2d074a60f82c07f5c2e9f7c6 188 Pfam PF02632 BioY family 29 170 7.5E-30 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UP12_11965 c4390b2b2d074a60f82c07f5c2e9f7c6 188 PIRSF PIRSF016661 1 179 1.1E-39 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 UP12_11965 c4390b2b2d074a60f82c07f5c2e9f7c6 188 Gene3D G3DSA:1.10.1760.20 1 177 1.3E-42 T 11-10-2018 UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 Pfam PF12848 ABC transporter 229 314 4.1E-20 T 11-10-2018 IPR032781 ABC-transporter extension domain UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 Pfam PF00005 ABC transporter 19 190 1.3E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 Gene3D G3DSA:3.40.50.300 2 284 1.5E-65 T 11-10-2018 UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 SUPERFAMILY SSF52540 3 244 1.49E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 SMART SM00382 27 237 1.5E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 SMART SM00382 348 517 4.9E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 SUPERFAMILY SSF52540 308 505 7.83E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 Pfam PF00005 ABC transporter 341 468 2.2E-22 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 Gene3D G3DSA:3.40.50.300 288 514 2.2E-44 T 11-10-2018 UP12_03805 c16252fa7ba0ac1f7b42ae66882bc9dc 517 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 Pfam PF01728 FtsJ-like methyltransferase 62 243 2.1E-18 T 11-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 SMART SM00363 6 71 8.8E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 PIRSF PIRSF005578 1 269 1.2E-103 T 11-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 SUPERFAMILY SSF55174 5 71 7.36E-12 T 11-10-2018 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 Gene3D G3DSA:3.40.50.150 65 282 1.0E-82 T 11-10-2018 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 Gene3D G3DSA:3.10.290.10 2 64 7.8E-24 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 Pfam PF01479 S4 domain 6 47 2.2E-8 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 SUPERFAMILY SSF53335 56 244 2.99E-21 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_10960 10e4ece3edfbefa852e3da2d3e589a32 284 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 3.6E-94 T 11-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 UP12_09085 c98a736d7a806808759d32376a749224 468 SUPERFAMILY SSF56024 48 224 7.63E-30 T 11-10-2018 UP12_09085 c98a736d7a806808759d32376a749224 468 SUPERFAMILY SSF56024 273 430 7.26E-23 T 11-10-2018 UP12_09085 c98a736d7a806808759d32376a749224 468 Gene3D G3DSA:3.30.870.10 45 241 6.2E-31 T 11-10-2018 UP12_09085 c98a736d7a806808759d32376a749224 468 SMART SM00155 368 395 6.1E-4 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_09085 c98a736d7a806808759d32376a749224 468 SMART SM00155 151 178 5.2 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_09085 c98a736d7a806808759d32376a749224 468 Gene3D G3DSA:3.30.870.10 258 461 1.8E-25 T 11-10-2018 UP12_09085 c98a736d7a806808759d32376a749224 468 Pfam PF13091 PLD-like domain 67 215 2.7E-16 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_09085 c98a736d7a806808759d32376a749224 468 Pfam PF13091 PLD-like domain 295 421 5.9E-13 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 Gene3D G3DSA:1.10.1740.10 14 96 3.2E-27 T 11-10-2018 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 54 67 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 Pfam PF04542 Sigma-70 region 2 27 99 4.3E-15 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 SUPERFAMILY SSF88659 100 168 3.14E-14 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 SUPERFAMILY SSF88946 6 99 9.26E-25 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 219 245 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 SUPERFAMILY SSF88659 163 251 1.4E-20 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 Gene3D G3DSA:1.20.140.160 98 252 1.7E-43 T 11-10-2018 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 Pfam PF04545 Sigma-70, region 4 200 247 3.3E-15 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 PIRSF PIRSF000770 5 255 4.3E-39 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 Pfam PF04539 Sigma-70 region 3 106 184 2.1E-10 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 PRINTS PR00046 Major sigma-70 factor signature 234 245 3.4E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 PRINTS PR00046 Major sigma-70 factor signature 219 234 3.4E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 PRINTS PR00046 Major sigma-70 factor signature 54 67 3.4E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 PRINTS PR00046 Major sigma-70 factor signature 78 86 3.4E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 PRINTS PR00046 Major sigma-70 factor signature 202 214 3.4E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 248 1.7E-31 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_08030 d8c87340d21e3a02fb2e1e3bf0a37e57 255 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 27 249 1.6E-85 T 11-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 UP12_05640 3ab4009ab1d31dacd2e1b84dc9f999c8 312 Gene3D G3DSA:3.40.47.10 1 312 4.3E-132 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_05640 3ab4009ab1d31dacd2e1b84dc9f999c8 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 6.5E-31 T 11-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UP12_05640 3ab4009ab1d31dacd2e1b84dc9f999c8 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 1 310 1.2E-141 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UP12_05640 3ab4009ab1d31dacd2e1b84dc9f999c8 312 SUPERFAMILY SSF53901 3 310 5.52E-72 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_05640 3ab4009ab1d31dacd2e1b84dc9f999c8 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 221 310 5.9E-36 T 11-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UP12_05640 3ab4009ab1d31dacd2e1b84dc9f999c8 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 310 71.713 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 UP12_01935 a2245fa6b2de70f137c2cd5fba200d91 254 Gene3D G3DSA:3.60.15.10 1 254 1.0E-65 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_01935 a2245fa6b2de70f137c2cd5fba200d91 254 SUPERFAMILY SSF56281 1 241 1.19E-19 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_01935 a2245fa6b2de70f137c2cd5fba200d91 254 Pfam PF13483 Beta-lactamase superfamily domain 3 205 4.0E-11 T 11-10-2018 UP12_08410 14b2e3173291dad36578c7f2139db99b 122 Gene3D G3DSA:1.10.3730.20 1 110 1.9E-35 T 11-10-2018 UP12_08410 14b2e3173291dad36578c7f2139db99b 122 SUPERFAMILY SSF103481 6 107 4.18E-22 T 11-10-2018 UP12_08410 14b2e3173291dad36578c7f2139db99b 122 Pfam PF00893 Small Multidrug Resistance protein 4 94 2.6E-29 T 11-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UP12_16075 4fc051bfbb03612a6e4948ac044262b6 301 Pfam PF01497 Periplasmic binding protein 39 273 3.3E-35 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_16075 4fc051bfbb03612a6e4948ac044262b6 301 Gene3D G3DSA:3.40.50.1980 145 301 2.6E-41 T 11-10-2018 UP12_16075 4fc051bfbb03612a6e4948ac044262b6 301 SUPERFAMILY SSF53807 38 284 2.24E-49 T 11-10-2018 UP12_16075 4fc051bfbb03612a6e4948ac044262b6 301 Gene3D G3DSA:3.40.50.1980 24 143 5.0E-18 T 11-10-2018 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 SUPERFAMILY SSF55920 3 248 4.32E-70 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 Pfam PF00557 Metallopeptidase family M24 11 240 2.6E-44 T 11-10-2018 IPR000994 Peptidase M24 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 4.1E-19 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 66 79 4.1E-19 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 4.1E-19 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 4.1E-19 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 Gene3D G3DSA:3.90.230.10 1 249 8.7E-86 T 11-10-2018 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 Hamap MF_01974 Methionine aminopeptidase [map]. 1 249 35.909 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_03910 0c0f55590b121e6aed214b8c86ca0701 249 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 248 1.1E-97 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 Gene3D G3DSA:1.10.150.310 156 209 4.3E-14 T 11-10-2018 UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 SMART SM00278 186 205 0.077 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 SMART SM00278 156 175 0.45 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 Pfam PF12836 Helix-hairpin-helix motif 144 207 4.1E-23 T 11-10-2018 UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 SUPERFAMILY SSF47781 123 208 8.45E-29 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 Gene3D G3DSA:3.10.560.10 52 155 1.7E-10 T 11-10-2018 UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 143 208 7.2E-25 T 11-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain UP12_11625 50d5bf66defa60ed88eaf817cd34bd02 209 Pfam PF10531 SLBB domain 68 119 5.4E-12 T 11-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_16740 570248da64af4cd17a8029bd09a2e81e 394 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 34 382 6.4E-81 T 11-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 UP12_16740 570248da64af4cd17a8029bd09a2e81e 394 Gene3D G3DSA:3.40.50.12580 205 369 4.3E-42 T 11-10-2018 UP12_16740 570248da64af4cd17a8029bd09a2e81e 394 Gene3D G3DSA:3.40.50.11820 36 204 1.2E-19 T 11-10-2018 UP12_16740 570248da64af4cd17a8029bd09a2e81e 394 SUPERFAMILY SSF53756 88 384 7.33E-26 T 11-10-2018 UP12_17105 85865b9896a59dfb8287590fb2c892cb 49 Pfam PF00471 Ribosomal protein L33 3 49 1.9E-22 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_17105 85865b9896a59dfb8287590fb2c892cb 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 1.2E-19 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_17105 85865b9896a59dfb8287590fb2c892cb 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 11-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17105 85865b9896a59dfb8287590fb2c892cb 49 Gene3D G3DSA:2.20.28.120 1 49 2.8E-23 T 11-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_17105 85865b9896a59dfb8287590fb2c892cb 49 SUPERFAMILY SSF57829 1 49 8.55E-19 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 UP12_17105 85865b9896a59dfb8287590fb2c892cb 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.535 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_13900 3aa01ab9c9f28c206f79ccbab82875c0 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 3.4E-130 T 11-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 UP12_13900 3aa01ab9c9f28c206f79ccbab82875c0 272 Gene3D G3DSA:3.90.226.10 1 209 1.7E-78 T 11-10-2018 UP12_13900 3aa01ab9c9f28c206f79ccbab82875c0 272 SUPERFAMILY SSF52096 5 267 1.42E-78 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_13900 3aa01ab9c9f28c206f79ccbab82875c0 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 UP12_13900 3aa01ab9c9f28c206f79ccbab82875c0 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 2.0E-91 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UP12_13900 3aa01ab9c9f28c206f79ccbab82875c0 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 55.7 T 11-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 UP12_13900 3aa01ab9c9f28c206f79ccbab82875c0 272 Gene3D G3DSA:1.10.12.10 210 260 2.8E-28 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal UP12_03835 9b60dd6a400eb701bc4a1159d73c84c9 231 SUPERFAMILY SSF142695 55 199 6.28E-41 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UP12_03835 9b60dd6a400eb701bc4a1159d73c84c9 231 Gene3D G3DSA:3.40.50.10990 41 203 2.2E-48 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UP12_03835 9b60dd6a400eb701bc4a1159d73c84c9 231 Pfam PF00925 GTP cyclohydrolase II 54 196 9.3E-42 T 11-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UP12_13230 00682c97bb7b944024152d9945a6e6b5 267 Hamap MF_00361 NAD kinase [nadK]. 6 267 20.174 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UP12_13230 00682c97bb7b944024152d9945a6e6b5 267 Pfam PF01513 ATP-NAD kinase 40 217 2.9E-18 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UP12_13230 00682c97bb7b944024152d9945a6e6b5 267 Gene3D G3DSA:3.40.50.10330 34 267 5.9E-75 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UP12_13230 00682c97bb7b944024152d9945a6e6b5 267 SUPERFAMILY SSF111331 17 266 7.63E-56 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UP12_13230 00682c97bb7b944024152d9945a6e6b5 267 Gene3D G3DSA:2.60.200.30 109 245 5.9E-75 T 11-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 Pfam PF00890 FAD binding domain 8 372 6.9E-77 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 Gene3D G3DSA:1.20.58.100 382 490 2.5E-21 T 11-10-2018 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 Gene3D G3DSA:3.50.50.60 8 381 5.2E-127 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 SUPERFAMILY SSF46977 411 507 5.36E-28 T 11-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 Gene3D G3DSA:3.90.700.10 232 338 5.2E-127 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 Pfam PF02910 Fumarate reductase flavoprotein C-term 414 503 1.5E-17 T 11-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 SUPERFAMILY SSF56425 222 332 1.42E-28 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 6 489 9.2E-168 T 11-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 SUPERFAMILY SSF51905 8 395 1.1E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.6E-5 T 11-10-2018 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 335 357 9.6E-5 T 11-10-2018 UP12_12205 c0d959f6eb45f2587452c96f5ca95200 524 PIRSF PIRSF000171 3 521 7.2E-31 T 11-10-2018 UP12_16035 e34d3011a151970d3e8ec0cdbd37a873 376 Pfam PF13439 Glycosyltransferase Family 4 17 181 4.4E-17 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UP12_16035 e34d3011a151970d3e8ec0cdbd37a873 376 Pfam PF00534 Glycosyl transferases group 1 193 310 5.0E-27 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 UP12_16035 e34d3011a151970d3e8ec0cdbd37a873 376 SUPERFAMILY SSF53756 6 310 1.96E-60 T 11-10-2018 UP12_16035 e34d3011a151970d3e8ec0cdbd37a873 376 Gene3D G3DSA:3.40.50.2000 178 309 7.4E-54 T 11-10-2018 UP12_16035 e34d3011a151970d3e8ec0cdbd37a873 376 Gene3D G3DSA:3.40.50.2000 17 177 7.4E-54 T 11-10-2018 UP12_15645 66ef6a27d2527bba5430acdc339842cf 468 PIRSF PIRSF006060 1 466 5.9E-55 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_15645 66ef6a27d2527bba5430acdc339842cf 468 Pfam PF13520 Amino acid permease 8 425 1.6E-52 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_15645 66ef6a27d2527bba5430acdc339842cf 468 Gene3D G3DSA:1.20.1740.10 2 467 1.9E-63 T 11-10-2018 UP12_11655 4ba4c4880a79e101bcb996fe438d6efa 96 Gene3D G3DSA:3.30.110.60 1 96 5.9E-37 T 11-10-2018 IPR035920 YhbY-like superfamily UP12_11655 4ba4c4880a79e101bcb996fe438d6efa 96 SMART SM01103 2 85 1.6E-41 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 UP12_11655 4ba4c4880a79e101bcb996fe438d6efa 96 SUPERFAMILY SSF75471 1 95 4.84E-31 T 11-10-2018 IPR035920 YhbY-like superfamily UP12_11655 4ba4c4880a79e101bcb996fe438d6efa 96 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 2.9E-21 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 UP12_11655 4ba4c4880a79e101bcb996fe438d6efa 96 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.1E-42 T 11-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 UP12_11655 4ba4c4880a79e101bcb996fe438d6efa 96 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 96 2.0E-39 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 UP12_02080 f1eb6620d469a106ccca67d0a03d77ad 271 Gene3D G3DSA:3.40.190.10 132 229 3.0E-66 T 11-10-2018 UP12_02080 f1eb6620d469a106ccca67d0a03d77ad 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 50 267 1.3E-54 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_02080 f1eb6620d469a106ccca67d0a03d77ad 271 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 73 86 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site UP12_02080 f1eb6620d469a106ccca67d0a03d77ad 271 SUPERFAMILY SSF53850 1 269 3.04E-61 T 11-10-2018 UP12_02080 f1eb6620d469a106ccca67d0a03d77ad 271 Gene3D G3DSA:3.40.190.10 48 260 3.0E-66 T 11-10-2018 UP12_02080 f1eb6620d469a106ccca67d0a03d77ad 271 SMART SM00062 49 268 7.1E-76 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_10240 4aedcc8c33f7e135330eda44b673f777 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 1.5E-272 T 11-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 UP12_10240 4aedcc8c33f7e135330eda44b673f777 492 Gene3D G3DSA:3.40.50.300 12 236 1.1E-10 T 11-10-2018 UP12_10240 4aedcc8c33f7e135330eda44b673f777 492 SUPERFAMILY SSF52540 19 224 1.47E-14 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10240 4aedcc8c33f7e135330eda44b673f777 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 9.6E-228 T 11-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 UP12_10240 4aedcc8c33f7e135330eda44b673f777 492 PIRSF PIRSF007466 1 492 6.9E-270 T 11-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 UP12_00095 1ac35febe204f282ab337a3194a79868 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 2.0E-32 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.0E-32 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 2.0E-32 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 2.0E-32 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 2.0E-32 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 SUPERFAMILY SSF55681 117 422 1.79E-105 T 11-10-2018 UP12_00095 1ac35febe204f282ab337a3194a79868 424 SUPERFAMILY SSF46589 1 113 3.87E-32 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 UP12_00095 1ac35febe204f282ab337a3194a79868 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 400 2.0E-37 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_00095 1ac35febe204f282ab337a3194a79868 424 PIRSF PIRSF001529 1 424 1.7E-191 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 6.6E-186 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.302 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 UP12_00095 1ac35febe204f282ab337a3194a79868 424 Gene3D G3DSA:1.10.287.40 1 105 2.4E-27 T 11-10-2018 UP12_00095 1ac35febe204f282ab337a3194a79868 424 Gene3D G3DSA:3.30.930.10 106 424 2.4E-129 T 11-10-2018 UP12_00095 1ac35febe204f282ab337a3194a79868 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 1.9E-34 T 11-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 Gene3D G3DSA:2.40.10.10 105 201 6.1E-74 T 11-10-2018 UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 Pfam PF00089 Trypsin 110 284 8.9E-16 T 11-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 PRINTS PR00839 V8 serine protease family signature 264 276 1.3E-13 T 11-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 PRINTS PR00839 V8 serine protease family signature 119 136 1.3E-13 T 11-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 PRINTS PR00839 V8 serine protease family signature 95 112 1.3E-13 T 11-10-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 SMART SM00020 97 296 1.3E-4 T 11-10-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 SUPERFAMILY SSF50494 89 297 3.12E-36 T 11-10-2018 IPR009003 Peptidase S1, PA clan UP12_08655 fbd1cdb4d4bc986e5be5a8c99dda217b 302 Gene3D G3DSA:2.40.10.10 90 277 6.1E-74 T 11-10-2018 UP12_05515 f214c8cb7e1a5fc05e463de43c3fa9db 285 Gene3D G3DSA:2.20.28.50 28 62 1.2E-43 T 11-10-2018 UP12_05515 f214c8cb7e1a5fc05e463de43c3fa9db 285 SUPERFAMILY SSF82549 1 283 1.18E-88 T 11-10-2018 UP12_05515 f214c8cb7e1a5fc05e463de43c3fa9db 285 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 280 3.2E-92 T 11-10-2018 IPR003797 DegV UP12_05515 f214c8cb7e1a5fc05e463de43c3fa9db 285 Gene3D G3DSA:3.40.50.10440 5 137 1.2E-43 T 11-10-2018 UP12_05515 f214c8cb7e1a5fc05e463de43c3fa9db 285 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 5.9E-84 T 11-10-2018 IPR003797 DegV UP12_05515 f214c8cb7e1a5fc05e463de43c3fa9db 285 Gene3D G3DSA:3.30.1180.10 156 284 2.3E-47 T 11-10-2018 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 PIRSF PIRSF000097 1 120 2.0E-39 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 PIRSF PIRSF000097 115 271 5.6E-54 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 PRINTS PR00069 Aldo-keto reductase signature 95 113 4.5E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 4.5E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 PRINTS PR00069 Aldo-keto reductase signature 125 142 4.5E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 PRINTS PR00069 Aldo-keto reductase signature 39 63 4.5E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 PRINTS PR00069 Aldo-keto reductase signature 159 188 4.5E-51 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 Gene3D G3DSA:3.20.20.100 2 275 2.3E-123 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 Pfam PF00248 Aldo/keto reductase family 18 261 4.7E-52 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 SUPERFAMILY SSF51430 7 267 4.98E-97 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_01350 9cbe3b3d64f1724a68820b82b9071383 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 Gene3D G3DSA:3.30.300.10 13 284 4.7E-182 T 11-10-2018 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 129 139 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 SUPERFAMILY SSF55973 5 111 5.49E-48 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 247 386 6.9E-71 T 11-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 SUPERFAMILY SSF55973 247 395 2.75E-70 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 Gene3D G3DSA:3.30.300.10 7 247 4.7E-182 T 11-10-2018 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 273 281 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 PIRSF PIRSF000497 1 398 2.5E-180 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 Gene3D G3DSA:3.30.300.10 104 389 4.7E-182 T 11-10-2018 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 2.6E-44 T 11-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 395 6.0E-189 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 397 59.924 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 Pfam PF02772 S-adenosylmethionine synthetase, central domain 128 245 2.0E-49 T 11-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_13740 6b650cce5eae84354fb2771c3ee2ba2b 400 SUPERFAMILY SSF55973 125 246 2.51E-52 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 Pfam PF07702 UTRA domain 91 229 7.9E-31 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 SUPERFAMILY SSF46785 4 77 1.44E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 SMART SM00345 9 68 4.6E-11 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 SMART SM00866 90 229 2.0E-27 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 66 1.1E-13 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 5 236 7.1E-96 T 11-10-2018 IPR012770 Trehalose operon transcriptional repressor UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 Gene3D G3DSA:1.10.10.10 5 72 6.3E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 SUPERFAMILY SSF64288 75 234 7.22E-40 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 9.9E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 9.9E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_03965 a77194fc7d13eaf7c6e4cd07993f93a7 242 Gene3D G3DSA:3.40.1410.10 88 228 1.2E-30 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 TIGRFAM TIGR00836 amt: ammonium transporter 5 400 1.2E-143 T 11-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 ProSitePatterns PS01219 Ammonium transporters signature. 157 182 - T 11-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 Pfam PF00909 Ammonium Transporter Family 7 400 3.2E-133 T 11-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 Gene3D G3DSA:1.10.3430.10 1 402 4.4E-146 T 11-10-2018 IPR029020 Ammonium/urea transporter UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 SUPERFAMILY SSF111352 3 380 3.27E-128 T 11-10-2018 UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 PRINTS PR00342 Rhesus blood group protein signature 101 117 2.7E-5 T 11-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 PRINTS PR00342 Rhesus blood group protein signature 225 247 2.7E-5 T 11-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 PRINTS PR00342 Rhesus blood group protein signature 194 212 2.7E-5 T 11-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 UP12_17055 a41476f13627bcb9f7fe1523fcc6debe 402 PRINTS PR00342 Rhesus blood group protein signature 280 298 2.7E-5 T 11-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 UP12_09045 53c88e51e6d022b7fe1c8d4d5800aa8d 518 Pfam PF15657 HNH/Endo VII superfamily nuclease toxins 445 516 3.4E-16 T 11-10-2018 IPR028048 HNH/Endo VII superfamily nuclease toxins UP12_09045 53c88e51e6d022b7fe1c8d4d5800aa8d 518 Pfam PF14449 Pre-toxin TG 243 308 1.2E-19 T 11-10-2018 IPR027797 Pre-toxin TG domain UP12_09045 53c88e51e6d022b7fe1c8d4d5800aa8d 518 Pfam PF04740 LXG domain of WXG superfamily 1 188 2.1E-40 T 11-10-2018 IPR006829 LXG domain UP12_07405 3f75a43829c8ee3d4b61baf59d26c830 122 PIRSF PIRSF018579 1 113 2.4E-45 T 11-10-2018 IPR009709 Protein of unknown function DUF1290 UP12_07405 3f75a43829c8ee3d4b61baf59d26c830 122 Pfam PF06947 Protein of unknown function (DUF1290) 22 107 8.1E-34 T 11-10-2018 IPR009709 Protein of unknown function DUF1290 UP12_07180 f31c55b49036f5164b44c65478a627fc 93 Gene3D G3DSA:1.10.287.750 5 93 1.8E-37 T 11-10-2018 IPR036270 UPF0358 superfamily UP12_07180 f31c55b49036f5164b44c65478a627fc 93 SUPERFAMILY SSF140404 7 84 2.35E-36 T 11-10-2018 IPR036270 UPF0358 superfamily UP12_07180 f31c55b49036f5164b44c65478a627fc 93 Pfam PF07408 Protein of unknown function (DUF1507) 9 91 1.1E-41 T 11-10-2018 IPR009983 Uncharacterised protein family UPF0358 UP12_07180 f31c55b49036f5164b44c65478a627fc 93 Hamap MF_01560 UPF0358 protein . 3 93 27.02 T 11-10-2018 IPR009983 Uncharacterised protein family UPF0358 UP12_01685 48329b11798dd18ceddea3d504fe6a83 281 Gene3D G3DSA:1.10.3720.10 83 275 1.7E-35 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01685 48329b11798dd18ceddea3d504fe6a83 281 SUPERFAMILY SSF161098 85 269 1.96E-39 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01685 48329b11798dd18ceddea3d504fe6a83 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 265 4.1E-23 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 618 38.666 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 Gene3D G3DSA:1.20.58.760 406 609 1.5E-75 T 11-10-2018 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 Gene3D G3DSA:1.10.8.60 331 405 2.4E-30 T 11-10-2018 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 Gene3D G3DSA:3.40.50.300 147 330 6.6E-70 T 11-10-2018 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 SMART SM00382 193 332 1.3E-23 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 ProSitePatterns PS00674 AAA-protein family signature. 300 318 - T 11-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 Pfam PF06480 FtsH Extracellular 9 104 1.2E-9 T 11-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 SUPERFAMILY SSF140990 411 605 5.23E-73 T 11-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 Pfam PF01434 Peptidase family M41 391 600 2.2E-88 T 11-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 SUPERFAMILY SSF52540 151 401 5.83E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 109 601 1.3E-246 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 UP12_00420 5c241ac9be491cf5a5ec2dd70b0a77b6 634 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 197 329 5.7E-44 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_07835 9f670daf7413b50a3096baf775275e07 386 Pfam PF08442 ATP-grasp domain 2 203 1.1E-84 T 11-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_07835 9f670daf7413b50a3096baf775275e07 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 11-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UP12_07835 9f670daf7413b50a3096baf775275e07 386 Pfam PF00549 CoA-ligase 262 381 1.9E-25 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UP12_07835 9f670daf7413b50a3096baf775275e07 386 Gene3D G3DSA:3.40.50.261 240 386 7.1E-57 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UP12_07835 9f670daf7413b50a3096baf775275e07 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 45.318 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_07835 9f670daf7413b50a3096baf775275e07 386 PIRSF PIRSF001554 1 386 1.5E-156 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_07835 9f670daf7413b50a3096baf775275e07 386 SUPERFAMILY SSF52210 239 386 1.57E-54 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 UP12_07835 9f670daf7413b50a3096baf775275e07 386 Gene3D G3DSA:3.30.470.20 1 234 1.2E-97 T 11-10-2018 UP12_07835 9f670daf7413b50a3096baf775275e07 386 SUPERFAMILY SSF56059 1 238 2.95E-83 T 11-10-2018 UP12_07835 9f670daf7413b50a3096baf775275e07 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.5E-168 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_07835 9f670daf7413b50a3096baf775275e07 386 Gene3D G3DSA:3.30.1490.20 21 104 1.2E-97 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UP12_04030 9655acf92159338dc37303595ebfc18e 239 Pfam PF01709 Transcriptional regulator 4 235 1.5E-82 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_04030 9655acf92159338dc37303595ebfc18e 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 1.4E-74 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_04030 9655acf92159338dc37303595ebfc18e 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 32.522 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_04030 9655acf92159338dc37303595ebfc18e 239 SUPERFAMILY SSF75625 1 238 4.97E-83 T 11-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_04030 9655acf92159338dc37303595ebfc18e 239 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 58.614 T 11-10-2018 IPR026562 Probable transcriptional regulatory protein YeeN UP12_04030 9655acf92159338dc37303595ebfc18e 239 Gene3D G3DSA:3.30.70.980 83 234 3.5E-48 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_04030 9655acf92159338dc37303595ebfc18e 239 Gene3D G3DSA:3.30.70.980 131 201 3.5E-48 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_04030 9655acf92159338dc37303595ebfc18e 239 Gene3D G3DSA:1.10.10.200 2 78 2.8E-23 T 11-10-2018 IPR017856 Integrase-like, N-terminal UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 42.418 T 11-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 1.3E-81 T 11-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 Gene3D G3DSA:1.10.286.10 1 54 1.4E-24 T 11-10-2018 UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 Gene3D G3DSA:3.30.1130.10 55 189 2.4E-60 T 11-10-2018 UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 11-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 11-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 SUPERFAMILY SSF55620 3 187 4.89E-79 T 11-10-2018 UP12_10230 66d948297a4e8b6d909279bb2412b8e1 189 Pfam PF01227 GTP cyclohydrolase I 9 186 7.7E-81 T 11-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 UP12_01200 35f8176a8a328ef5607f2b308347d722 315 SUPERFAMILY SSF53474 47 309 2.36E-30 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_01200 35f8176a8a328ef5607f2b308347d722 315 Pfam PF00561 alpha/beta hydrolase fold 66 173 8.3E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_01200 35f8176a8a328ef5607f2b308347d722 315 Gene3D G3DSA:3.40.50.1820 51 313 2.2E-49 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_12605 f6fb30a7b1b2ff43418402a2bbac5056 204 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 8 187 1.5E-42 T 11-10-2018 IPR006490 Phage major tail protein, phi13 family UP12_12605 f6fb30a7b1b2ff43418402a2bbac5056 204 Pfam PF04630 Phage tail tube protein 44 186 1.0E-12 T 11-10-2018 IPR006724 Phage tail tube protein 1 UP12_16145 8406f26208a969bde4f4333adeada8db 101 Pfam PF05154 TM2 domain 25 76 1.4E-15 T 11-10-2018 IPR007829 TM2 domain UP12_00080 f66479841b7400188f9b603939b61c9d 492 SUPERFAMILY SSF46785 7 80 9.1E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_00080 f66479841b7400188f9b603939b61c9d 492 SUPERFAMILY SSF53383 94 478 1.17E-97 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_00080 f66479841b7400188f9b603939b61c9d 492 Gene3D G3DSA:3.40.640.10 152 371 2.8E-115 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_00080 f66479841b7400188f9b603939b61c9d 492 Gene3D G3DSA:3.90.1150.10 115 474 2.8E-115 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_00080 f66479841b7400188f9b603939b61c9d 492 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 76 6.8E-17 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_00080 f66479841b7400188f9b603939b61c9d 492 Gene3D G3DSA:1.10.10.10 1 77 5.5E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_00080 f66479841b7400188f9b603939b61c9d 492 Pfam PF00155 Aminotransferase class I and II 118 472 2.6E-32 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_00080 f66479841b7400188f9b603939b61c9d 492 SMART SM00345 17 76 2.6E-18 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 SUPERFAMILY SSF53223 4 273 6.47E-102 T 11-10-2018 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 ProSitePatterns PS00331 Malic enzymes signature. 270 286 - T 11-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 SMART SM01274 82 264 1.2E-91 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 Gene3D G3DSA:3.40.50.10380 16 271 3.4E-102 T 11-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 Pfam PF00390 Malic enzyme, N-terminal domain 82 264 5.2E-73 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 SUPERFAMILY SSF51735 274 564 3.55E-90 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 Pfam PF03949 Malic enzyme, NAD binding domain 274 535 7.7E-102 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 Gene3D G3DSA:3.40.50.720 272 566 4.6E-109 T 11-10-2018 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PIRSF PIRSF000106 1 566 4.2E-227 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 SMART SM00919 274 535 1.3E-118 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PRINTS PR00072 Malic enzyme signature 270 286 3.1E-72 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PRINTS PR00072 Malic enzyme signature 88 112 3.1E-72 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PRINTS PR00072 Malic enzyme signature 186 208 3.1E-72 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PRINTS PR00072 Malic enzyme signature 301 317 3.1E-72 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PRINTS PR00072 Malic enzyme signature 150 179 3.1E-72 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PRINTS PR00072 Malic enzyme signature 245 263 3.1E-72 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_17290 12179e49eed02b88c9d46ca2d5e86c0c 566 PRINTS PR00072 Malic enzyme signature 413 429 3.1E-72 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_07630 47cbe16fd8ba6053ebdffde89b5764e6 89 Pfam PF04025 Domain of unknown function (DUF370) 5 77 7.5E-37 T 11-10-2018 IPR007169 Extracellular matrix regulatory protein A UP12_07630 47cbe16fd8ba6053ebdffde89b5764e6 89 Hamap MF_01503 UPF0296 protein . 3 82 29.086 T 11-10-2018 IPR007169 Extracellular matrix regulatory protein A UP12_07630 47cbe16fd8ba6053ebdffde89b5764e6 89 ProDom PD063023 UPF0296 YLZA BA4010/GBAA4010/BAS3723 BLI01788/BL02292 BT9727_3613 BC3870 TM1690 CBDBA43 SYC0519_C BCE33L3631 5 78 1.0E-35 T 11-10-2018 IPR007169 Extracellular matrix regulatory protein A UP12_14550 b6817bb6df9f45267566c7b815d2aaf9 307 Pfam PF10076 Uncharacterised protein conserved in bacteria (DUF2313) 5 148 1.4E-35 T 11-10-2018 IPR018755 Bacteriophage Mu-like, Gp48 UP12_11970 e39340bee4a7d2e163e8eeae3140b7eb 94 Hamap MF_01448 UPF0473 protein . 4 89 21.587 T 11-10-2018 IPR009711 Uncharacterised protein family UPF0473 UP12_11970 e39340bee4a7d2e163e8eeae3140b7eb 94 Pfam PF06949 Protein of unknown function (DUF1292) 13 88 5.3E-19 T 11-10-2018 IPR009711 Uncharacterised protein family UPF0473 UP12_05255 32b53a125259dd10fede20e9f0f63bb5 479 Gene3D G3DSA:1.10.10.10 2 77 6.9E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05255 32b53a125259dd10fede20e9f0f63bb5 479 SUPERFAMILY SSF53383 123 477 2.67E-77 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_05255 32b53a125259dd10fede20e9f0f63bb5 479 SMART SM00345 17 76 2.1E-13 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_05255 32b53a125259dd10fede20e9f0f63bb5 479 Pfam PF00155 Aminotransferase class I and II 157 472 2.8E-19 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_05255 32b53a125259dd10fede20e9f0f63bb5 479 Gene3D G3DSA:3.40.640.10 110 472 1.7E-102 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_05255 32b53a125259dd10fede20e9f0f63bb5 479 SUPERFAMILY SSF46785 5 80 1.36E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_05255 32b53a125259dd10fede20e9f0f63bb5 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 5.9E-11 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_06825 23be074e64f6c4c6e440d5386fe4d599 80 Gene3D G3DSA:3.30.720.20 1 80 1.4E-36 T 11-10-2018 IPR038073 YkuJ-like superfamily UP12_06825 23be074e64f6c4c6e440d5386fe4d599 80 SUPERFAMILY SSF143567 2 79 2.88E-28 T 11-10-2018 IPR038073 YkuJ-like superfamily UP12_06825 23be074e64f6c4c6e440d5386fe4d599 80 Pfam PF08796 Protein of unknown function (DUF1797) 7 78 1.4E-25 T 11-10-2018 IPR014904 Protein of unknown function DUF1797 UP12_06825 23be074e64f6c4c6e440d5386fe4d599 80 PIRSF PIRSF037356 1 79 5.2E-35 T 11-10-2018 IPR014904 Protein of unknown function DUF1797 UP12_06945 ea002bb082dd5f9e41cc7a62c2dedb9b 208 Pfam PF04893 Yip1 domain 15 192 5.3E-17 T 11-10-2018 IPR006977 Yip1 domain GO:0016020 UP12_18590 367a46db28a7a7d5649e4de5219a15d6 417 Gene3D G3DSA:1.20.1250.20 5 407 9.2E-36 T 11-10-2018 UP12_18590 367a46db28a7a7d5649e4de5219a15d6 417 Pfam PF07690 Major Facilitator Superfamily 15 372 1.6E-25 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_18590 367a46db28a7a7d5649e4de5219a15d6 417 SUPERFAMILY SSF103473 12 403 3.79E-37 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 428 1.9E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 Gene3D G3DSA:3.30.565.10 284 435 1.2E-29 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 SUPERFAMILY SSF55874 286 426 1.44E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 SMART SM00387 318 429 1.5E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 1.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 1.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 1.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_15750 36458e9a779466f5b7b39a67f3d2148c 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 1.3E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 Gene3D G3DSA:3.30.870.10 127 319 3.8E-42 T 11-10-2018 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 31 500 4.0E-140 T 11-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 SMART SM00155 413 440 8.4E-7 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 SMART SM00155 237 264 1.9E-5 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 Gene3D G3DSA:3.30.870.10 320 472 1.6E-29 T 11-10-2018 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 Pfam PF13091 PLD-like domain 155 297 1.7E-15 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 Pfam PF13091 PLD-like domain 342 467 8.3E-29 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 Hamap MF_01916 Cardiolipin synthase. 34 500 39.276 T 11-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 SUPERFAMILY SSF56024 132 331 6.28E-51 T 11-10-2018 UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 Pfam PF13396 Phospholipase_D-nuclease N-terminal 41 82 3.9E-7 T 11-10-2018 IPR027379 Cardiolipin synthase N-terminal UP12_17430 c29f23325d0959875f5218db5e1ef0e2 500 SUPERFAMILY SSF56024 289 483 7.4E-44 T 11-10-2018 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 205 1.3E-42 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 SUPERFAMILY SSF52096 483 792 5.85E-39 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Gene3D G3DSA:3.90.226.10 485 688 1.9E-29 T 11-10-2018 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 SUPERFAMILY SSF48179 206 325 8.08E-22 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Gene3D G3DSA:3.40.50.720 1 208 6.2E-64 T 11-10-2018 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Pfam PF00378 Enoyl-CoA hydratase/isomerase 490 624 2.0E-11 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 375 416 4.9E-5 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 208 306 4.5E-11 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 SUPERFAMILY SSF48179 357 446 8.5E-17 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 SUPERFAMILY SSF51735 4 206 2.39E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Gene3D G3DSA:1.10.1040.10 209 327 2.2E-18 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_15460 ea5ea9da016cb7779c406d96cc5a4752 795 Gene3D G3DSA:1.10.1040.10 359 476 4.1E-8 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_04940 a0ea2d3af3d06bb2feb0d0b0b9df43ae 168 Pfam PF00582 Universal stress protein family 5 168 1.9E-36 T 11-10-2018 IPR006016 UspA UP12_04940 a0ea2d3af3d06bb2feb0d0b0b9df43ae 168 Gene3D G3DSA:3.40.50.620 3 168 4.3E-36 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_04940 a0ea2d3af3d06bb2feb0d0b0b9df43ae 168 PRINTS PR01438 Universal stress protein signature 128 140 4.0E-14 T 11-10-2018 IPR006015 Universal stress protein A UP12_04940 a0ea2d3af3d06bb2feb0d0b0b9df43ae 168 PRINTS PR01438 Universal stress protein signature 146 168 4.0E-14 T 11-10-2018 IPR006015 Universal stress protein A UP12_04940 a0ea2d3af3d06bb2feb0d0b0b9df43ae 168 PRINTS PR01438 Universal stress protein signature 4 22 4.0E-14 T 11-10-2018 IPR006015 Universal stress protein A UP12_04940 a0ea2d3af3d06bb2feb0d0b0b9df43ae 168 SUPERFAMILY SSF52402 5 168 1.76E-31 T 11-10-2018 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Gene3D G3DSA:3.40.710.10 234 582 3.6E-96 T 11-10-2018 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Gene3D G3DSA:3.90.1310.10 60 207 6.4E-61 T 11-10-2018 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Pfam PF00905 Penicillin binding protein transpeptidase domain 267 575 2.9E-81 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 SUPERFAMILY SSF56519 56 240 2.22E-46 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 223 1.5E-22 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 SUPERFAMILY SSF56601 192 592 1.18E-87 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Pfam PF03793 PASTA domain 660 711 1.1E-6 T 11-10-2018 IPR005543 PASTA domain UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Pfam PF03793 PASTA domain 602 655 2.2E-5 T 11-10-2018 IPR005543 PASTA domain UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 SUPERFAMILY SSF54184 659 705 3.79E-10 T 11-10-2018 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 SUPERFAMILY SSF54184 602 655 3.27E-9 T 11-10-2018 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Gene3D G3DSA:3.30.70.2110 79 162 6.4E-61 T 11-10-2018 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 Gene3D G3DSA:2.20.70.70 55 226 6.4E-61 T 11-10-2018 UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 SMART SM00740 597 657 5.2E-6 T 11-10-2018 IPR005543 PASTA domain UP12_07350 aad995f48513c5ce3e0e5e8b836a06ad 716 SMART SM00740 658 714 0.0071 T 11-10-2018 IPR005543 PASTA domain UP12_15170 703dc04e233563d0688b7161bb480c2b 78 SUPERFAMILY SSF117916 2 77 4.74E-27 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UP12_15170 703dc04e233563d0688b7161bb480c2b 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 65 2.0E-22 T 11-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 UP12_15170 703dc04e233563d0688b7161bb480c2b 78 Gene3D G3DSA:3.30.300.130 1 78 9.0E-33 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UP12_15170 703dc04e233563d0688b7161bb480c2b 78 Pfam PF01106 NifU-like domain 10 75 5.6E-28 T 11-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 UP12_06670 30a65444fc15eec2f0fc6e5efef48f5c 438 PIRSF PIRSF038958 1 437 5.7E-71 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type UP12_06670 30a65444fc15eec2f0fc6e5efef48f5c 438 Pfam PF01943 Polysaccharide biosynthesis protein 5 293 5.4E-26 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 UP12_06395 cf1fe735c33cbf02d91defa6232435ac 142 SUPERFAMILY SSF82784 5 137 2.09E-34 T 11-10-2018 IPR036102 OsmC/Ohr superfamily UP12_06395 cf1fe735c33cbf02d91defa6232435ac 142 Gene3D G3DSA:3.30.300.20 47 139 1.8E-32 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_06395 cf1fe735c33cbf02d91defa6232435ac 142 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 137 1.0E-48 T 11-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 UP12_06395 cf1fe735c33cbf02d91defa6232435ac 142 Pfam PF02566 OsmC-like protein 44 137 8.5E-19 T 11-10-2018 IPR003718 OsmC/Ohr family UP12_06395 cf1fe735c33cbf02d91defa6232435ac 142 Gene3D G3DSA:2.20.25.10 3 45 3.2E-12 T 11-10-2018 UP12_18165 5a0d513d17928cf84b92f00be92f8989 436 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 14 428 2.6E-104 T 11-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 UP12_18165 5a0d513d17928cf84b92f00be92f8989 436 Pfam PF02378 Phosphotransferase system, EIIC 29 360 3.9E-45 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_18165 5a0d513d17928cf84b92f00be92f8989 436 PIRSF PIRSF006351 1 436 3.2E-131 T 11-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 UP12_01120 9b83445e9694eb65bc24e100cecfcbad 118 Gene3D G3DSA:1.10.8.290 1 118 5.5E-55 T 11-10-2018 IPR023204 SP1917 domain superfamily UP12_01120 9b83445e9694eb65bc24e100cecfcbad 118 PIRSF PIRSF033199 1 116 4.3E-58 T 11-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 UP12_01120 9b83445e9694eb65bc24e100cecfcbad 118 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 5 115 8.1E-54 T 11-10-2018 IPR014580 Uncharacterised conserved protein UCP033199 UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.5E-21 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 Pfam PF03466 LysR substrate binding domain 90 287 1.1E-49 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 SUPERFAMILY SSF53850 90 291 2.07E-45 T 11-10-2018 UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 Gene3D G3DSA:3.40.190.290 93 291 3.7E-58 T 11-10-2018 UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 Gene3D G3DSA:1.10.10.10 1 92 2.1E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_17900 9c2ed35fe8d3aa51bc8719689fa976cb 295 SUPERFAMILY SSF46785 2 111 9.74E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 SUPERFAMILY SSF90123 5 327 3.79E-80 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 Pfam PF00005 ABC transporter 358 507 7.4E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 SUPERFAMILY SSF52540 332 577 2.84E-97 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 Gene3D G3DSA:3.40.50.300 331 580 3.2E-94 T 11-10-2018 UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 SMART SM00382 367 553 4.6E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 Gene3D G3DSA:1.20.1560.10 3 323 9.2E-108 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04390 d4a62d390e2fa2a1e8bfbf395a6b3be8 580 Pfam PF00664 ABC transporter transmembrane region 23 289 2.7E-48 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_17420 234e481585aef436fac74fdd47670f06 332 PIRSF PIRSF028757 1 332 1.4E-79 T 11-10-2018 IPR003507 Peptidase family S66 UP12_17420 234e481585aef436fac74fdd47670f06 332 SUPERFAMILY SSF52317 4 165 4.03E-43 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_17420 234e481585aef436fac74fdd47670f06 332 Gene3D G3DSA:3.40.50.10740 4 164 1.5E-55 T 11-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal UP12_17420 234e481585aef436fac74fdd47670f06 332 Gene3D G3DSA:3.50.30.60 165 332 4.8E-52 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_17420 234e481585aef436fac74fdd47670f06 332 SUPERFAMILY SSF141986 171 320 1.57E-37 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_17420 234e481585aef436fac74fdd47670f06 332 Pfam PF02016 LD-carboxypeptidase 13 317 1.6E-68 T 11-10-2018 IPR003507 Peptidase family S66 UP12_06360 93094d289054e86977d789b98ec24692 104 SUPERFAMILY SSF103481 6 101 9.55E-16 T 11-10-2018 UP12_06360 93094d289054e86977d789b98ec24692 104 Gene3D G3DSA:1.10.3730.20 1 104 2.7E-24 T 11-10-2018 UP12_06360 93094d289054e86977d789b98ec24692 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.2E-26 T 11-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 Pfam PF09397 Ftsk gamma domain 847 908 1.1E-28 T 11-10-2018 IPR018541 FtsK gamma domain UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 SUPERFAMILY SSF52540 532 822 8.5E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 Gene3D G3DSA:3.40.50.300 556 835 3.5E-114 T 11-10-2018 UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 SMART SM00382 594 771 9.4E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 Gene3D G3DSA:1.10.10.10 840 906 5.3E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 Gene3D G3DSA:3.30.980.40 452 555 2.7E-36 T 11-10-2018 UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 SUPERFAMILY SSF46785 847 911 1.02E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 Pfam PF01580 FtsK/SpoIIIE family 559 750 2.0E-66 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UP12_13445 83f94c52dfe5a8076709fe3f3509d06d 916 SMART SM00843 845 910 2.5E-36 T 11-10-2018 IPR018541 FtsK gamma domain UP12_18095 2692f7cce529b5c0cf6692bbbb32b835 295 SUPERFAMILY SSF53807 40 294 2.28E-52 T 11-10-2018 UP12_18095 2692f7cce529b5c0cf6692bbbb32b835 295 Gene3D G3DSA:3.40.50.1980 38 123 2.0E-33 T 11-10-2018 UP12_18095 2692f7cce529b5c0cf6692bbbb32b835 295 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 8 293 1.1E-134 T 11-10-2018 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 UP12_18095 2692f7cce529b5c0cf6692bbbb32b835 295 Gene3D G3DSA:3.40.50.1980 124 294 4.6E-57 T 11-10-2018 UP12_18095 2692f7cce529b5c0cf6692bbbb32b835 295 Pfam PF01497 Periplasmic binding protein 42 271 7.2E-39 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_03035 46b3d2bf880ca876fca98eed8458ae90 183 SUPERFAMILY SSF55729 15 181 1.22E-29 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_03035 46b3d2bf880ca876fca98eed8458ae90 183 Pfam PF00583 Acetyltransferase (GNAT) family 54 153 2.2E-15 T 11-10-2018 IPR000182 GNAT domain UP12_03035 46b3d2bf880ca876fca98eed8458ae90 183 Gene3D G3DSA:3.40.630.30 14 179 1.3E-36 T 11-10-2018 UP12_05155 4baafde256dce8fa1218ab58809850f8 312 SUPERFAMILY SSF53800 3 308 1.28E-90 T 11-10-2018 UP12_05155 4baafde256dce8fa1218ab58809850f8 312 ProSitePatterns PS00534 Ferrochelatase signature. 178 196 - T 11-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UP12_05155 4baafde256dce8fa1218ab58809850f8 312 Pfam PF00762 Ferrochelatase 5 307 2.7E-84 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UP12_05155 4baafde256dce8fa1218ab58809850f8 312 TIGRFAM TIGR00109 hemH: ferrochelatase 2 308 7.9E-108 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UP12_05155 4baafde256dce8fa1218ab58809850f8 312 Gene3D G3DSA:3.40.50.1400 148 289 1.2E-108 T 11-10-2018 UP12_05155 4baafde256dce8fa1218ab58809850f8 312 Hamap MF_00323 Ferrochelatase [hemH]. 4 308 32.66 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 UP12_05155 4baafde256dce8fa1218ab58809850f8 312 Gene3D G3DSA:3.40.50.1400 8 304 1.2E-108 T 11-10-2018 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 Gene3D G3DSA:3.30.1360.60 1 76 2.1E-27 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 534 546 - T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 Pfam PF02378 Phosphotransferase system, EIIC 109 386 4.3E-33 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 Pfam PF00367 phosphotransferase system, EIIB 8 41 1.0E-14 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 Gene3D G3DSA:2.70.70.10 459 618 3.5E-55 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_18285 e33b280b6d95068faded45f4b61df72f 635 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 471 595 1.7E-49 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 SUPERFAMILY SSF55604 6 78 6.54E-22 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 473 592 6.2E-46 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 4 616 1.4E-223 T 11-10-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 UP12_18285 e33b280b6d95068faded45f4b61df72f 635 SUPERFAMILY SSF51261 466 616 2.62E-52 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 SUPERFAMILY SSF55174 14 101 5.89E-17 T 11-10-2018 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 Gene3D G3DSA:3.30.2350.10 81 304 4.9E-76 T 11-10-2018 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 Pfam PF01479 S4 domain 15 61 8.4E-14 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 Gene3D G3DSA:3.10.290.10 2 70 9.9E-22 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 SMART SM00363 15 72 2.4E-13 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 10 301 1.4E-109 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 Pfam PF00849 RNA pseudouridylate synthase 88 242 1.4E-36 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_07525 8df5c27746516e0a044c5dd0c7564ff8 304 SUPERFAMILY SSF55120 74 301 3.08E-78 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 SUPERFAMILY SSF48295 342 446 9.68E-37 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Gene3D G3DSA:1.10.8.60 277 345 3.2E-30 T 11-10-2018 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 SMART SM00382 143 271 1.1E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 144 164 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 190 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 242 269 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 405 424 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 SUPERFAMILY SSF52540 111 323 4.02E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 446 35.249 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 SMART SM00760 355 424 1.4E-41 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Gene3D G3DSA:3.40.50.300 97 275 5.0E-55 T 11-10-2018 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Gene3D G3DSA:1.10.1750.10 346 446 1.0E-35 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Pfam PF00308 Bacterial dnaA protein 111 327 1.4E-107 T 11-10-2018 IPR013317 Chromosomal replication initiator protein DnaA UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 445 3.7E-189 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Gene3D G3DSA:3.30.300.180 1 82 1.4E-32 T 11-10-2018 IPR038454 DnaA, N-terminal domain superfamily UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 356 424 8.4E-31 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 ProSitePatterns PS01008 DnaA protein signature. 405 424 - T 11-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 UP12_00005 48e87b3f8db2009b97f6c9b76744830d 446 Pfam PF11638 DnaA N-terminal domain 7 66 7.3E-18 T 11-10-2018 IPR024633 DnaA N-terminal domain UP12_00900 681b29d25b022a05804c37e4598843fe 130 SUPERFAMILY SSF54211 5 130 1.78E-49 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_00900 681b29d25b022a05804c37e4598843fe 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 11-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 UP12_00900 681b29d25b022a05804c37e4598843fe 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.395 T 11-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid UP12_00900 681b29d25b022a05804c37e4598843fe 130 Gene3D G3DSA:3.30.230.10 1 130 1.1E-52 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_00900 681b29d25b022a05804c37e4598843fe 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 5.8E-48 T 11-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 UP12_00310 d780395f39affb40f767146cfdce32d2 98 Pfam PF04026 SpoVG 2 81 3.5E-35 T 11-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 UP12_00310 d780395f39affb40f767146cfdce32d2 98 Gene3D G3DSA:3.30.1120.40 1 98 1.7E-39 T 11-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 UP12_00310 d780395f39affb40f767146cfdce32d2 98 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.136 T 11-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 UP12_00310 d780395f39affb40f767146cfdce32d2 98 SUPERFAMILY SSF160537 2 84 6.41E-33 T 11-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 SUPERFAMILY SSF69189 286 379 7.65E-19 T 11-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 Gene3D G3DSA:2.60.410.10 286 376 4.0E-19 T 11-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 SMART SM00936 286 377 7.1E-26 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 139 5.9E-18 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 69 80 5.9E-18 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 149 162 5.9E-18 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 SUPERFAMILY SSF56601 2 286 2.26E-82 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 Gene3D G3DSA:3.40.710.10 17 285 2.7E-91 T 11-10-2018 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 36 266 1.4E-90 T 11-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 UP12_10565 45c5b8fe6bfc8159ebfe61228f4485f0 395 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 286 377 9.9E-19 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_14240 aeba366febe39a0d59b68dad0007d0d2 118 Gene3D G3DSA:2.40.10.370 1 118 1.4E-48 T 11-10-2018 IPR038667 XkdH-like superfamily UP12_14240 aeba366febe39a0d59b68dad0007d0d2 118 Pfam PF12206 Domain of unknown function (DUF3599) 1 116 1.7E-54 T 11-10-2018 IPR024556 Protein of unknown function DUF3599 UP12_14240 aeba366febe39a0d59b68dad0007d0d2 118 ProDom PD031312 YQBH LIN1274 PHAGE XKDH PHAGE-LIKE PBSX RELATED ELEMENT 1 114 4.0E-43 T 11-10-2018 IPR024556 Protein of unknown function DUF3599 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 SUPERFAMILY SSF52402 174 388 8.6E-52 T 11-10-2018 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 5.4E-69 T 11-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 Gene3D G3DSA:3.30.2130.30 1 174 4.1E-62 T 11-10-2018 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 Pfam PF02926 THUMP domain 37 162 3.5E-25 T 11-10-2018 IPR004114 THUMP domain GO:0003723 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 Gene3D G3DSA:3.40.50.620 175 400 2.7E-74 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_13320 56c9f365132b16adeaa8049ca5983823 401 SUPERFAMILY SSF143437 3 173 3.14E-54 T 11-10-2018 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 401 167.527 T 11-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 378 7.7E-143 T 11-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 UP12_13320 56c9f365132b16adeaa8049ca5983823 401 SMART SM00981 74 165 7.1E-25 T 11-10-2018 IPR004114 THUMP domain GO:0003723 UP12_10615 43a57ed66b30c1f0cc620069d8a28a50 393 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 7 386 1.6E-100 T 11-10-2018 IPR005287 Conserved hypothetical protein CHP00375 UP12_10615 43a57ed66b30c1f0cc620069d8a28a50 393 Gene3D G3DSA:3.20.20.140 2 238 6.4E-11 T 11-10-2018 UP12_10615 43a57ed66b30c1f0cc620069d8a28a50 393 SUPERFAMILY SSF47781 309 370 1.63E-6 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_10615 43a57ed66b30c1f0cc620069d8a28a50 393 Pfam PF13263 PHP-associated 196 241 2.1E-7 T 11-10-2018 UP12_10615 43a57ed66b30c1f0cc620069d8a28a50 393 SUPERFAMILY SSF89550 29 243 2.55E-11 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.828 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 SUPERFAMILY SSF75620 8 351 2.88E-135 T 11-10-2018 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 SMART SM00937 62 177 7.0E-63 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 Pfam PF03462 PCRF domain 8 202 3.8E-74 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 Gene3D G3DSA:1.20.58.410 1 101 1.9E-8 T 11-10-2018 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 Pfam PF00472 RF-1 domain 210 319 7.4E-41 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 353 6.4E-173 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 Gene3D G3DSA:3.30.160.20 209 295 6.7E-96 T 11-10-2018 UP12_17275 fcbb4067d7e5af5f20871189b67a18c4 355 Gene3D G3DSA:3.30.70.1660 110 340 6.7E-96 T 11-10-2018 UP12_06770 1ddd4a9ad7494b2580bb2eb42c97152b 436 Gene3D G3DSA:1.20.1250.20 22 231 7.1E-14 T 11-10-2018 UP12_06770 1ddd4a9ad7494b2580bb2eb42c97152b 436 Gene3D G3DSA:1.20.1250.20 242 435 1.2E-20 T 11-10-2018 UP12_06770 1ddd4a9ad7494b2580bb2eb42c97152b 436 Pfam PF11700 Vacuole effluxer Atg22 like 23 432 7.1E-36 T 11-10-2018 IPR024671 Autophagy-related protein 22-like UP12_06770 1ddd4a9ad7494b2580bb2eb42c97152b 436 SUPERFAMILY SSF103473 24 433 1.1E-44 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_06770 1ddd4a9ad7494b2580bb2eb42c97152b 436 ProSitePatterns PS00217 Sugar transport proteins signature 2. 349 374 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_03885 bd978e2dc744eb921287a3be820acb4c 161 Pfam PF05870 Phenolic acid decarboxylase (PAD) 1 158 3.3E-82 T 11-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 UP12_03885 bd978e2dc744eb921287a3be820acb4c 161 PIRSF PIRSF011561 1 161 3.0E-92 T 11-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 UP12_03885 bd978e2dc744eb921287a3be820acb4c 161 Gene3D G3DSA:2.40.128.20 1 161 2.9E-81 T 11-10-2018 IPR012674 Calycin UP12_03885 bd978e2dc744eb921287a3be820acb4c 161 SUPERFAMILY SSF50814 2 160 1.17E-72 T 11-10-2018 IPR012674 Calycin UP12_03885 bd978e2dc744eb921287a3be820acb4c 161 ProDom PD022010 DECARBOXYLASE ACID PHENOLIC P-COUMARIC LYASE 4.1.1.- PAD PADC FERULATE PROBABLE 1 160 4.0E-91 T 11-10-2018 IPR008729 Phenolic acid decarboxylase GO:0016831 UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 SUPERFAMILY SSF53335 170 413 1.88E-47 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 SUPERFAMILY SSF110849 4 93 1.74E-12 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 PIRSF PIRSF036758 1 424 1.2E-136 T 11-10-2018 IPR015840 DNA methyase, ParB domain-containing UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 Gene3D G3DSA:3.40.50.150 174 412 9.0E-44 T 11-10-2018 UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 Pfam PF01555 DNA methylase 196 409 2.3E-23 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 Pfam PF02195 ParB-like nuclease domain 5 92 6.1E-7 T 11-10-2018 IPR003115 ParB/Sulfiredoxin UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 SMART SM00470 4 93 2.7E-4 T 11-10-2018 IPR003115 ParB/Sulfiredoxin UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 194 208 3.4E-13 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 350 367 3.4E-13 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 392 412 3.4E-13 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 369 387 3.4E-13 T 11-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 UP12_14295 3e0d149884dbdff0208b857c9887ad0e 425 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 198 204 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UP12_00905 5e79829af59681ea39302abf302c24b6 171 SUPERFAMILY SSF55729 2 166 2.88E-51 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_00905 5e79829af59681ea39302abf302c24b6 171 Gene3D G3DSA:3.40.630.30 2 168 1.1E-56 T 11-10-2018 UP12_00905 5e79829af59681ea39302abf302c24b6 171 Pfam PF13302 Acetyltransferase (GNAT) domain 7 141 2.9E-32 T 11-10-2018 IPR000182 GNAT domain UP12_02135 a4858c0b4f16e450dec0564237d5a918 281 SUPERFAMILY SSF55781 13 161 2.01E-19 T 11-10-2018 UP12_02135 a4858c0b4f16e450dec0564237d5a918 281 Gene3D G3DSA:3.30.450.40 4 161 9.7E-16 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_02135 a4858c0b4f16e450dec0564237d5a918 281 Gene3D G3DSA:3.30.750.24 162 276 1.8E-28 T 11-10-2018 IPR036513 STAS domain superfamily UP12_02135 a4858c0b4f16e450dec0564237d5a918 281 Pfam PF13185 GAF domain 14 150 3.6E-8 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_02135 a4858c0b4f16e450dec0564237d5a918 281 SMART SM00065 12 159 2.4E-5 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_02135 a4858c0b4f16e450dec0564237d5a918 281 SUPERFAMILY SSF52091 166 273 6.47E-12 T 11-10-2018 IPR036513 STAS domain superfamily UP12_18345 1b079c7fa32b0ba08cea4beec5d57439 793 Pfam PF05547 Immune inhibitor A peptidase M6 139 787 2.3E-263 T 11-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 UP12_18345 1b079c7fa32b0ba08cea4beec5d57439 793 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 155 477 2.0E-82 T 11-10-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 UP12_18345 1b079c7fa32b0ba08cea4beec5d57439 793 SUPERFAMILY SSF55486 250 422 2.2E-18 T 11-10-2018 UP12_18345 1b079c7fa32b0ba08cea4beec5d57439 793 PIRSF PIRSF007519 1 793 2.0E-296 T 11-10-2018 IPR012300 Peptidase M6, InhA UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 Gene3D G3DSA:2.40.50.600 349 413 2.3E-19 T 11-10-2018 UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 Pfam PF04055 Radical SAM superfamily 130 276 1.7E-7 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 Pfam PF12544 Lysine-2,3-aminomutase 321 445 3.5E-61 T 11-10-2018 IPR025895 Lysine-2,3-aminomutase, C-terminal domain UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 TIGRFAM TIGR00238 TIGR00238: KamA family protein 14 342 2.6E-149 T 11-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 Gene3D G3DSA:3.20.20.70 63 348 9.5E-121 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 SUPERFAMILY SSF102114 114 358 2.22E-33 T 11-10-2018 UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 TIGRFAM TIGR03820 lys_2_3_AblA: lysine-2,3-aminomutase 23 425 5.8E-194 T 11-10-2018 IPR022459 Lysine-2,3-aminomutase KEGG: 00310+5.4.3.2 UP12_09665 72e35b979e53302ef745c8a3c0e88d9c 466 PIRSF PIRSF004911 2 399 1.1E-162 T 11-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase UP12_18270 f06577b9a86ba8781a04f3443b0a3974 439 Pfam PF02447 GntP family permease 1 437 1.3E-165 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UP12_18270 f06577b9a86ba8781a04f3443b0a3974 439 PIRSF PIRSF002746 1 439 2.3E-156 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UP12_18270 f06577b9a86ba8781a04f3443b0a3974 439 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 438 3.8E-174 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 1.8E-89 T 11-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Gene3D G3DSA:1.10.40.90 363 405 1.0E-23 T 11-10-2018 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Gene3D G3DSA:1.10.1790.20 950 1128 1.1E-67 T 11-10-2018 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1192 18.714 T 11-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Gene3D G3DSA:2.40.50.100 966 1029 1.1E-67 T 11-10-2018 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Gene3D G3DSA:1.10.274.100 479 659 2.4E-49 T 11-10-2018 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 385 6.4E-9 T 11-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 378 474 4.3E-29 T 11-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 11-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 1.9E-37 T 11-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 1129 1.7E-67 T 11-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 1.4E-14 T 11-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Gene3D G3DSA:1.10.132.30 660 794 1.4E-59 T 11-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 SUPERFAMILY SSF64484 5 1181 0.0 T 11-10-2018 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 Gene3D G3DSA:1.10.150.390 1130 1190 1.5E-28 T 11-10-2018 UP12_00685 416c8a1794a2f00746638f638c20d1ce 1199 SMART SM00663 224 503 7.7E-185 T 11-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_16005 22a6fdba43f8c065be43dec606c4e0d1 228 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 175 203 1.8E-5 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_16005 22a6fdba43f8c065be43dec606c4e0d1 228 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 136 168 0.002 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_16005 22a6fdba43f8c065be43dec606c4e0d1 228 SUPERFAMILY SSF51161 10 223 2.08E-47 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_16005 22a6fdba43f8c065be43dec606c4e0d1 228 Gene3D G3DSA:2.160.10.10 104 212 8.3E-29 T 11-10-2018 UP12_16005 22a6fdba43f8c065be43dec606c4e0d1 228 Gene3D G3DSA:3.40.50.20 13 100 5.3E-12 T 11-10-2018 UP12_16005 22a6fdba43f8c065be43dec606c4e0d1 228 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 18 217 3.9E-62 T 11-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 SMART SM00316 149 211 0.017 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 SMART SM00316 67 133 18.0 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 SMART SM00316 2 62 0.34 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 PIRSF PIRSF012524 1 282 7.7E-110 T 11-10-2018 IPR014464 Conserved virulence factor B UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 Pfam PF13509 S1 domain 4 62 4.2E-16 T 11-10-2018 IPR039566 Conserved virulence factor B, S1 domain UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 Gene3D G3DSA:2.40.50.140 71 148 2.2E-25 T 11-10-2018 UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 Gene3D G3DSA:2.40.50.140 151 218 1.2E-18 T 11-10-2018 UP12_05500 ce393eda58e4b0eba91b07fc6a90dd87 282 Gene3D G3DSA:1.10.10.10 220 279 1.4E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15300 e80e2d1628eefd52f676ab9fa431490a 338 Pfam PF01032 FecCD transport family 21 332 6.0E-89 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_15300 e80e2d1628eefd52f676ab9fa431490a 338 SUPERFAMILY SSF81345 10 332 8.5E-79 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15300 e80e2d1628eefd52f676ab9fa431490a 338 Gene3D G3DSA:1.10.3470.10 8 337 2.5E-91 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_02180 ba61b5f19fcf97bacfaf3b47a9ae7694 464 PIRSF PIRSF036492 14 460 4.3E-85 T 11-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 UP12_02180 ba61b5f19fcf97bacfaf3b47a9ae7694 464 Pfam PF00171 Aldehyde dehydrogenase family 3 458 3.5E-173 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_02180 ba61b5f19fcf97bacfaf3b47a9ae7694 464 SUPERFAMILY SSF53720 5 461 3.4E-171 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_02180 ba61b5f19fcf97bacfaf3b47a9ae7694 464 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 7 456 7.8E-214 T 11-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 UP12_02180 ba61b5f19fcf97bacfaf3b47a9ae7694 464 Gene3D G3DSA:3.40.309.10 235 427 1.1E-179 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_02180 ba61b5f19fcf97bacfaf3b47a9ae7694 464 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UP12_02180 ba61b5f19fcf97bacfaf3b47a9ae7694 464 Gene3D G3DSA:3.40.605.10 5 456 1.1E-179 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_06060 5d54b94ca3a0ca46a044a797f7fa571a 141 SUPERFAMILY SSF55729 1 125 4.49E-25 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_06060 5d54b94ca3a0ca46a044a797f7fa571a 141 Pfam PF13673 Acetyltransferase (GNAT) domain 44 127 2.1E-15 T 11-10-2018 IPR000182 GNAT domain UP12_06060 5d54b94ca3a0ca46a044a797f7fa571a 141 Gene3D G3DSA:3.40.630.30 1 138 1.5E-23 T 11-10-2018 UP12_11285 ab57e90b69a0a2507bd77d114367e729 166 Pfam PF02618 YceG-like family 105 165 8.8E-8 T 11-10-2018 IPR003770 Endolytic murein transglycosylase UP12_11285 ab57e90b69a0a2507bd77d114367e729 166 Gene3D G3DSA:1.10.8.1150 99 166 2.1E-14 T 11-10-2018 UP12_07605 4d4d2d703daddd4b61a672ed0b08999f 261 Pfam PF01903 CbiX 134 234 1.6E-20 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 UP12_07605 4d4d2d703daddd4b61a672ed0b08999f 261 Pfam PF01903 CbiX 10 114 6.3E-27 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 UP12_07605 4d4d2d703daddd4b61a672ed0b08999f 261 Gene3D G3DSA:3.40.50.1400 1 123 1.4E-26 T 11-10-2018 UP12_07605 4d4d2d703daddd4b61a672ed0b08999f 261 Gene3D G3DSA:3.40.50.1400 124 243 4.5E-20 T 11-10-2018 UP12_07605 4d4d2d703daddd4b61a672ed0b08999f 261 SUPERFAMILY SSF53800 2 242 2.51E-50 T 11-10-2018 UP12_14940 00f873663687b2df37730a232e5b5c22 159 Pfam PF01899 Na+/H+ ion antiporter subunit 9 156 1.8E-43 T 11-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 UP12_14940 00f873663687b2df37730a232e5b5c22 159 PIRSF PIRSF019239 1 159 2.4E-46 T 11-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 UP12_06270 0668d2cb0810095f70a9d4b422fb0f76 274 Gene3D G3DSA:3.40.50.720 1 161 2.6E-31 T 11-10-2018 UP12_06270 0668d2cb0810095f70a9d4b422fb0f76 274 SUPERFAMILY SSF51735 3 157 3.13E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06270 0668d2cb0810095f70a9d4b422fb0f76 274 SUPERFAMILY SSF48179 159 266 3.06E-17 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_06270 0668d2cb0810095f70a9d4b422fb0f76 274 Gene3D G3DSA:1.10.3730.10 162 265 4.1E-14 T 11-10-2018 UP12_06270 0668d2cb0810095f70a9d4b422fb0f76 274 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 6.8E-16 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UP12_06270 0668d2cb0810095f70a9d4b422fb0f76 274 PIRSF PIRSF000193 1 266 1.4E-68 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_06270 0668d2cb0810095f70a9d4b422fb0f76 274 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 263 1.4E-15 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_06720 6703893cf768a9eac9f7fa9e567f7bd8 342 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 5 342 9.2E-156 T 11-10-2018 IPR023897 Spore photoproduct lyase GO:0003913 UP12_06720 6703893cf768a9eac9f7fa9e567f7bd8 342 Gene3D G3DSA:3.40.50.12110 3 115 2.2E-46 T 11-10-2018 UP12_06720 6703893cf768a9eac9f7fa9e567f7bd8 342 SUPERFAMILY SSF102114 85 300 3.27E-6 T 11-10-2018 UP12_06720 6703893cf768a9eac9f7fa9e567f7bd8 342 Gene3D G3DSA:3.80.30.30 116 342 2.7E-91 T 11-10-2018 UP12_14800 bef096c3f3c5e482bbcfb928e23fb438 387 Gene3D G3DSA:3.40.50.1970 1 184 3.0E-57 T 11-10-2018 UP12_14800 bef096c3f3c5e482bbcfb928e23fb438 387 SUPERFAMILY SSF56796 2 384 9.29E-116 T 11-10-2018 UP12_14800 bef096c3f3c5e482bbcfb928e23fb438 387 Gene3D G3DSA:1.20.1090.10 185 386 1.9E-45 T 11-10-2018 UP12_14800 bef096c3f3c5e482bbcfb928e23fb438 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 369 2.6E-100 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 UP12_14800 bef096c3f3c5e482bbcfb928e23fb438 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 UP12_14800 bef096c3f3c5e482bbcfb928e23fb438 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 UP12_00415 2cb55f37701c98371e6e5adeb32716d1 179 Pfam PF00156 Phosphoribosyl transferase domain 14 159 7.3E-25 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 UP12_00415 2cb55f37701c98371e6e5adeb32716d1 179 SUPERFAMILY SSF53271 3 178 8.52E-59 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_00415 2cb55f37701c98371e6e5adeb32716d1 179 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 8 173 3.3E-69 T 11-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 UP12_00415 2cb55f37701c98371e6e5adeb32716d1 179 Gene3D G3DSA:3.40.50.2020 1 179 3.6E-66 T 11-10-2018 UP12_07235 f775d868ceb2adb93ec9894ccbdf8ff5 121 Gene3D G3DSA:3.30.310.100 1 121 4.0E-46 T 11-10-2018 IPR036491 YugN-like superfamily UP12_07235 f775d868ceb2adb93ec9894ccbdf8ff5 121 Pfam PF08868 YugN-like family 8 98 2.5E-13 T 11-10-2018 IPR014967 Uncharacterised protein family, YugN-like UP12_07235 f775d868ceb2adb93ec9894ccbdf8ff5 121 SUPERFAMILY SSF160755 2 114 4.18E-39 T 11-10-2018 IPR036491 YugN-like superfamily UP12_04660 9432db0f3f658dceb72ef4c4f7a21ce6 235 Gene3D G3DSA:2.60.120.1270 29 232 1.4E-76 T 11-10-2018 IPR038682 YrpD-like superfamily UP12_04660 9432db0f3f658dceb72ef4c4f7a21ce6 235 Pfam PF15493 Domain of unknown function, YrpD 34 230 2.0E-84 T 11-10-2018 IPR029143 Protein of unknown function, YrpD UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 SUPERFAMILY SSF46785 7 141 8.41E-31 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 Pfam PF01047 MarR family 41 93 1.3E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 Gene3D G3DSA:1.10.10.10 2 140 9.0E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 3.6E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 3.6E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 3.6E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03005 34eb885dd12492cb2c98a2645c850cdd 157 SMART SM00347 29 129 4.3E-19 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 Pfam PF07690 Major Facilitator Superfamily 19 276 5.4E-38 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 PRINTS PR01035 Tetracycline resistance protein signature 341 364 4.9E-9 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 PRINTS PR01035 Tetracycline resistance protein signature 20 36 4.9E-9 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 PRINTS PR01035 Tetracycline resistance protein signature 169 189 4.9E-9 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 PRINTS PR01035 Tetracycline resistance protein signature 306 326 4.9E-9 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 PRINTS PR01035 Tetracycline resistance protein signature 141 163 4.9E-9 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 Gene3D G3DSA:1.20.1250.20 4 395 8.3E-65 T 11-10-2018 UP12_08235 80bf671a3d713adc1d642ee276dac909 408 SUPERFAMILY SSF103473 8 397 1.57E-68 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 Gene3D G3DSA:3.10.310.10 6 280 2.8E-110 T 11-10-2018 UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 Gene3D G3DSA:3.10.310.10 126 274 2.8E-110 T 11-10-2018 UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 282 6.3E-97 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 Pfam PF01678 Diaminopimelate epimerase 161 276 2.0E-32 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 Pfam PF01678 Diaminopimelate epimerase 6 130 5.4E-34 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 38.334 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 SUPERFAMILY SSF54506 3 284 6.77E-50 T 11-10-2018 UP12_15145 2ca1adfd1d5a8f9fb17f0761cd0adf40 284 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 11-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 Pfam PF03466 LysR substrate binding domain 88 290 2.4E-43 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 Gene3D G3DSA:3.40.190.290 91 293 3.6E-49 T 11-10-2018 UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.2E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.2E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.2E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 SUPERFAMILY SSF46785 1 86 3.07E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 Gene3D G3DSA:1.10.10.10 1 90 1.5E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 SUPERFAMILY SSF53850 90 292 5.35E-42 T 11-10-2018 UP12_05980 641ca325300c6a41ab53a62c70ae3873 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.7E-20 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_10500 af63661500fab90504d4a4f1078f4590 145 Gene3D G3DSA:2.40.100.10 1 145 6.1E-59 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily UP12_10500 af63661500fab90504d4a4f1078f4590 145 PIRSF PIRSF001467 2 144 1.8E-40 T 11-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 UP12_10500 af63661500fab90504d4a4f1078f4590 145 SUPERFAMILY SSF50891 10 137 4.38E-47 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily UP12_10500 af63661500fab90504d4a4f1078f4590 145 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 10 135 9.2E-41 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UP12_10500 af63661500fab90504d4a4f1078f4590 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 2.1E-25 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UP12_10500 af63661500fab90504d4a4f1078f4590 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 2.1E-25 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UP12_10500 af63661500fab90504d4a4f1078f4590 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 2.1E-25 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UP12_10500 af63661500fab90504d4a4f1078f4590 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 2.1E-25 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UP12_10500 af63661500fab90504d4a4f1078f4590 145 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 2.1E-25 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 UP12_10500 af63661500fab90504d4a4f1078f4590 145 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 11-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 UP12_09505 1173d1682997e5657d6c1d09df373ebd 494 Gene3D G3DSA:3.40.309.10 269 458 2.7E-204 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_09505 1173d1682997e5657d6c1d09df373ebd 494 Gene3D G3DSA:3.40.605.10 24 486 2.7E-204 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_09505 1173d1682997e5657d6c1d09df373ebd 494 SUPERFAMILY SSF53720 14 492 8.77E-187 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_09505 1173d1682997e5657d6c1d09df373ebd 494 Pfam PF00171 Aldehyde dehydrogenase family 29 488 1.4E-194 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_09505 1173d1682997e5657d6c1d09df373ebd 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UP12_10735 0525a2c885f1e3c5eb8fad76a4243116 344 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 10 330 9.1E-96 T 11-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 UP12_10735 0525a2c885f1e3c5eb8fad76a4243116 344 Gene3D G3DSA:3.20.20.70 8 344 2.9E-127 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_10735 0525a2c885f1e3c5eb8fad76a4243116 344 SUPERFAMILY SSF51395 9 340 9.3E-111 T 11-10-2018 UP12_10735 0525a2c885f1e3c5eb8fad76a4243116 344 Hamap MF_01614 NADPH dehydrogenase [namA]. 8 344 65.77 T 11-10-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 Pfam PF07687 Peptidase dimerisation domain 209 309 8.5E-11 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 Gene3D G3DSA:3.30.70.360 211 321 6.9E-184 T 11-10-2018 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 PIRSF PIRSF037215 1 410 1.5E-191 T 11-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 410 7.7E-204 T 11-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 SUPERFAMILY SSF53187 2 406 6.29E-82 T 11-10-2018 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 Hamap MF_00550 Peptidase T [pepT]. 2 406 59.113 T 11-10-2018 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 Pfam PF01546 Peptidase family M20/M25/M40 141 403 4.1E-13 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 140 179 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 SUPERFAMILY SSF55031 211 322 1.15E-37 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_18240 c633159e4d8b733914f2f9d5714b38aa 410 Gene3D G3DSA:3.40.630.10 5 402 6.9E-184 T 11-10-2018 UP12_18180 3f80f8526c01d5c6e860960cf71b5db7 141 ProDom PD085159 YWQH COILED COIL 1 140 1.0E-18 T 11-10-2018 IPR020326 Uncharacterised protein family YwqH UP12_18180 3f80f8526c01d5c6e860960cf71b5db7 141 Pfam PF16888 Domain of unknown function (DUF5082) 15 106 4.5E-9 T 11-10-2018 IPR031681 Protein of unknown function DUF5082 UP12_10300 c575a34b42402802744db7d2e9b2879f 215 Pfam PF12945 Flagellar protein YcgR 3 90 1.8E-17 T 11-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal UP12_10300 c575a34b42402802744db7d2e9b2879f 215 Gene3D G3DSA:2.40.10.220 100 208 6.2E-13 T 11-10-2018 UP12_10300 c575a34b42402802744db7d2e9b2879f 215 SUPERFAMILY SSF141371 99 164 2.35E-6 T 11-10-2018 UP12_10300 c575a34b42402802744db7d2e9b2879f 215 Pfam PF07238 PilZ domain 99 205 5.6E-11 T 11-10-2018 IPR009875 PilZ domain GO:0035438 UP12_03290 db110b553d4d4ed8d76ee4d78f951111 150 Gene3D G3DSA:2.40.50.1020 35 149 2.8E-12 T 11-10-2018 UP12_03290 db110b553d4d4ed8d76ee4d78f951111 150 SMART SM00850 49 146 5.3E-22 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UP12_03290 db110b553d4d4ed8d76ee4d78f951111 150 Pfam PF04397 LytTr DNA-binding domain 50 145 7.4E-22 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 142 1.5E-44 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 SUPERFAMILY SSF64518 1 322 4.84E-91 T 11-10-2018 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 Gene3D G3DSA:1.20.1330.10 230 273 4.6E-17 T 11-10-2018 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 Gene3D G3DSA:1.10.8.410 274 322 6.5E-29 T 11-10-2018 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 PRINTS PR00207 Flagellin signature 74 93 3.0E-25 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 PRINTS PR00207 Flagellin signature 35 52 3.0E-25 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 PRINTS PR00207 Flagellin signature 111 134 3.0E-25 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 Gene3D G3DSA:1.20.1330.10 43 143 2.1E-57 T 11-10-2018 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 Gene3D G3DSA:1.20.58.1830 3 31 2.1E-57 T 11-10-2018 UP12_05960 1ca8958233592fdda8bb1b7e00cf48f2 322 Pfam PF00700 Bacterial flagellin C-terminal helical region 237 321 8.1E-32 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 Gene3D G3DSA:3.10.310.30 542 655 6.5E-10 T 11-10-2018 UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 Gene3D G3DSA:3.90.1640.10 322 541 1.1E-54 T 11-10-2018 UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 Pfam PF01368 DHH family 339 496 8.7E-22 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 SMART SM00267 132 299 4.0E-11 T 11-10-2018 IPR000160 GGDEF domain UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 PIRSF PIRSF026583 1 659 6.5E-272 T 11-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 Gene3D G3DSA:3.30.450.20 54 161 2.3E-35 T 11-10-2018 UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 SUPERFAMILY SSF64182 339 644 3.27E-68 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily UP12_19030 2188962e2f4dc66496fffc367bcd5072 659 Pfam PF02272 DHHA1 domain 518 649 5.3E-14 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 UP12_11720 28d2e492a355d8a7fdd91a18bf3dbaf0 470 Gene3D G3DSA:3.90.640.20 152 237 1.3E-13 T 11-10-2018 IPR037126 PdaC/RsiV-like superfamily UP12_11720 28d2e492a355d8a7fdd91a18bf3dbaf0 470 Pfam PF01522 Polysaccharide deacetylase 273 386 6.6E-31 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_11720 28d2e492a355d8a7fdd91a18bf3dbaf0 470 Gene3D G3DSA:3.30.565.40 41 149 3.5E-11 T 11-10-2018 UP12_11720 28d2e492a355d8a7fdd91a18bf3dbaf0 470 Pfam PF13739 Domain of unknown function (DUF4163) 55 134 8.7E-7 T 11-10-2018 IPR025303 Deacetylase PdaC UP12_11720 28d2e492a355d8a7fdd91a18bf3dbaf0 470 SUPERFAMILY SSF88713 267 457 4.65E-57 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_11720 28d2e492a355d8a7fdd91a18bf3dbaf0 470 Gene3D G3DSA:3.20.20.370 238 458 6.0E-62 T 11-10-2018 UP12_07780 e372b92cac137a715719076671c2b8f2 446 SUPERFAMILY SSF47446 329 430 2.78E-39 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 Pfam PF02978 Signal peptide binding domain 329 427 3.0E-35 T 11-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 Gene3D G3DSA:1.20.120.140 6 307 5.3E-129 T 11-10-2018 UP12_07780 e372b92cac137a715719076671c2b8f2 446 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 5.3E-79 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 SUPERFAMILY SSF52540 43 355 5.13E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07780 e372b92cac137a715719076671c2b8f2 446 Gene3D G3DSA:3.40.50.300 91 286 5.3E-129 T 11-10-2018 UP12_07780 e372b92cac137a715719076671c2b8f2 446 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 8.3E-23 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 434 35.846 T 11-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 Gene3D G3DSA:1.10.260.30 328 444 5.7E-45 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 SMART SM00962 101 297 4.4E-122 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 SMART SM00382 100 302 1.6E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_07780 e372b92cac137a715719076671c2b8f2 446 SMART SM00963 2 87 1.1E-34 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07780 e372b92cac137a715719076671c2b8f2 446 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 1.1E-191 T 11-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 UP12_08190 7b2fa68cd41a56985ce37bddd90a18a0 197 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 7 193 3.7E-105 T 11-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B UP12_08190 7b2fa68cd41a56985ce37bddd90a18a0 197 SUPERFAMILY SSF52507 5 184 2.49E-30 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UP12_08190 7b2fa68cd41a56985ce37bddd90a18a0 197 Gene3D G3DSA:3.40.50.1950 1 196 1.1E-58 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 UP12_08190 7b2fa68cd41a56985ce37bddd90a18a0 197 PIRSF PIRSF001390 1 197 5.3E-81 T 11-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B UP12_08190 7b2fa68cd41a56985ce37bddd90a18a0 197 Pfam PF02441 Flavoprotein 7 168 1.2E-19 T 11-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 UP12_04175 05e77602f92b0f9b4f44a3b8d4caa969 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 9.8E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_04175 05e77602f92b0f9b4f44a3b8d4caa969 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 9.8E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_04175 05e77602f92b0f9b4f44a3b8d4caa969 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 19 50 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_04175 05e77602f92b0f9b4f44a3b8d4caa969 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 47 4.6E-14 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_04175 05e77602f92b0f9b4f44a3b8d4caa969 192 Gene3D G3DSA:1.10.357.10 1 190 1.3E-53 T 11-10-2018 UP12_04175 05e77602f92b0f9b4f44a3b8d4caa969 192 SUPERFAMILY SSF46689 3 77 4.36E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_04175 05e77602f92b0f9b4f44a3b8d4caa969 192 SUPERFAMILY SSF48498 75 168 9.93E-11 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_00850 608809e732b4bd5a9ebf3fc55cc4543b 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.611 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00850 608809e732b4bd5a9ebf3fc55cc4543b 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00850 608809e732b4bd5a9ebf3fc55cc4543b 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 5.8E-24 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00850 608809e732b4bd5a9ebf3fc55cc4543b 37 Pfam PF00444 Ribosomal protein L36 1 37 3.2E-19 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00850 608809e732b4bd5a9ebf3fc55cc4543b 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 2.0E-8 T 11-10-2018 UP12_00850 608809e732b4bd5a9ebf3fc55cc4543b 37 SUPERFAMILY SSF57840 1 37 6.28E-17 T 11-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_13245 a6b8c71c6f1c695aa87f87720ee5bc3e 378 Pfam PF07730 Histidine kinase 178 240 4.6E-21 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UP12_13245 a6b8c71c6f1c695aa87f87720ee5bc3e 378 SUPERFAMILY SSF55874 253 366 1.18E-9 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13245 a6b8c71c6f1c695aa87f87720ee5bc3e 378 Gene3D G3DSA:3.30.565.10 242 369 3.3E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13245 a6b8c71c6f1c695aa87f87720ee5bc3e 378 SUPERFAMILY SSF103473 23 161 4.19E-6 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 Gene3D G3DSA:3.40.190.10 59 374 4.9E-111 T 11-10-2018 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 PRINTS PR00181 Maltose binding protein signature 81 99 1.9E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 PRINTS PR00181 Maltose binding protein signature 141 160 1.9E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 PRINTS PR00181 Maltose binding protein signature 374 393 1.9E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 PRINTS PR00181 Maltose binding protein signature 162 181 1.9E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 PRINTS PR00181 Maltose binding protein signature 316 337 1.9E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 Gene3D G3DSA:3.40.190.10 150 407 4.9E-111 T 11-10-2018 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 SUPERFAMILY SSF53850 48 412 1.37E-91 T 11-10-2018 UP12_18515 3d788cc7eaed4c4f4fcc52eb1ed7828d 421 Pfam PF13416 Bacterial extracellular solute-binding protein 58 359 2.9E-52 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 SUPERFAMILY SSF53218 186 329 1.7E-34 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 SMART SM00852 189 328 1.3E-33 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 Gene3D G3DSA:2.170.190.11 50 150 1.5E-94 T 11-10-2018 UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 324 1.3E-27 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 176 3.2E-38 T 11-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 Pfam PF00994 Probable molybdopterin binding domain 189 326 1.6E-23 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 Gene3D G3DSA:2.40.340.10 338 412 4.1E-16 T 11-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 Gene3D G3DSA:3.90.105.10 28 183 1.5E-94 T 11-10-2018 UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 SUPERFAMILY SSF63882 7 185 4.32E-49 T 11-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 Pfam PF03454 MoeA C-terminal region (domain IV) 342 412 2.7E-20 T 11-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 Gene3D G3DSA:3.40.980.10 184 326 1.5E-94 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily UP12_06920 39b828bb44a6ac6fbd0e5bac40b88f8d 425 SUPERFAMILY SSF63867 340 413 4.32E-18 T 11-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 Pfam PF00561 alpha/beta hydrolase fold 29 261 4.5E-26 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00412 Epoxide hydrolase signature 249 271 3.8E-5 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00412 Epoxide hydrolase signature 216 232 3.8E-5 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00412 Epoxide hydrolase signature 98 111 3.8E-5 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00412 Epoxide hydrolase signature 34 52 3.8E-5 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 Gene3D G3DSA:3.40.50.1820 6 273 7.2E-60 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 SUPERFAMILY SSF53474 14 271 1.33E-58 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 9.9E-16 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 9.9E-16 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 9.9E-16 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_14825 284cbbc9a2afcb451d71f20ff304cc10 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 9.9E-16 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_19315 0a0f8397bdebfaff1d4c8bdac3840990 543 SUPERFAMILY SSF52540 33 439 7.43E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_19315 0a0f8397bdebfaff1d4c8bdac3840990 543 Gene3D G3DSA:3.40.50.300 225 446 5.0E-48 T 11-10-2018 UP12_19315 0a0f8397bdebfaff1d4c8bdac3840990 543 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 43 467 4.8E-119 T 11-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 SMART SM00363 1 60 5.3E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 Gene3D G3DSA:3.30.70.1560 129 213 3.2E-55 T 11-10-2018 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 228 1.0E-44 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 Gene3D G3DSA:3.10.290.10 1 59 1.1E-17 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 Pfam PF00849 RNA pseudouridylate synthase 62 195 4.6E-16 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 SUPERFAMILY SSF55174 1 59 1.24E-12 T 11-10-2018 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 SUPERFAMILY SSF55120 45 234 7.61E-39 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 Gene3D G3DSA:3.30.70.580 62 231 3.2E-55 T 11-10-2018 UP12_13550 e5d6f8df107a22ff2cba5e4093ce30fd 238 Pfam PF01479 S4 domain 1 48 1.0E-11 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 334 3.6E-149 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 339 8.2E-37 T 11-10-2018 IPR010918 PurM-like, C-terminal domain UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 340 47.68 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 SUPERFAMILY SSF55326 4 166 2.99E-49 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 Gene3D G3DSA:3.90.650.10 168 345 1.5E-70 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 Gene3D G3DSA:3.30.1330.10 1 167 3.0E-68 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 161 9.8E-17 T 11-10-2018 IPR016188 PurM-like, N-terminal domain UP12_03375 eca9fa3b24a2d0d229f0d5a9c3ecaf2c 346 SUPERFAMILY SSF56042 168 338 2.24E-57 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily UP12_07935 3b783155ecb64c7d2a065d11d807d354 263 Pfam PF00460 Flagella basal body rod protein 5 35 2.3E-12 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 UP12_07935 3b783155ecb64c7d2a065d11d807d354 263 SUPERFAMILY SSF117143 91 223 3.92E-35 T 11-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like UP12_07935 3b783155ecb64c7d2a065d11d807d354 263 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 242 7.9E-57 T 11-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 UP12_07935 3b783155ecb64c7d2a065d11d807d354 263 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 134 8.4E-41 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G UP12_07935 3b783155ecb64c7d2a065d11d807d354 263 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 244 4.2E-30 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G UP12_07935 3b783155ecb64c7d2a065d11d807d354 263 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 261 7.7E-24 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain UP12_07935 3b783155ecb64c7d2a065d11d807d354 263 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 Gene3D G3DSA:3.40.190.10 165 268 2.0E-35 T 11-10-2018 UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 SUPERFAMILY SSF53850 87 277 2.93E-32 T 11-10-2018 UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 SUPERFAMILY SSF46785 2 111 1.01E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 Gene3D G3DSA:1.10.10.10 1 88 5.8E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-6 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-6 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-6 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 Pfam PF03466 LysR substrate binding domain 87 289 2.4E-34 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.4E-18 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_03700 369fdd21a9ebde36159338c41919cc3d 302 Gene3D G3DSA:3.40.190.10 91 276 2.0E-35 T 11-10-2018 UP12_07580 43cde1df8d806ae8ebb17b03c6de970f 233 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 24 233 6.6E-95 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 UP12_07580 43cde1df8d806ae8ebb17b03c6de970f 233 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 38 209 3.3E-54 T 11-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 UP12_07580 43cde1df8d806ae8ebb17b03c6de970f 233 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 233 42.266 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 UP12_07580 43cde1df8d806ae8ebb17b03c6de970f 233 SUPERFAMILY SSF52402 16 197 7.33E-53 T 11-10-2018 UP12_07580 43cde1df8d806ae8ebb17b03c6de970f 233 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 43 231 1.8E-80 T 11-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 UP12_07580 43cde1df8d806ae8ebb17b03c6de970f 233 PIRSF PIRSF000857 5 233 2.5E-90 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 UP12_07580 43cde1df8d806ae8ebb17b03c6de970f 233 Gene3D G3DSA:3.40.50.620 7 233 1.5E-74 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_12285 0152b09e5520e749aeef5bee0b049518 339 SUPERFAMILY SSF53067 147 328 1.34E-49 T 11-10-2018 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 Gene3D G3DSA:3.30.420.40 151 313 2.6E-128 T 11-10-2018 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 2.3E-59 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 2.3E-59 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 296 322 2.3E-59 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 2.3E-59 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 2.3E-59 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 SUPERFAMILY SSF53067 7 144 1.12E-36 T 11-10-2018 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 Pfam PF06723 MreB/Mbl protein 7 330 2.4E-147 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 Gene3D G3DSA:3.30.420.40 9 323 2.6E-128 T 11-10-2018 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 332 1.8E-159 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 UP12_12285 0152b09e5520e749aeef5bee0b049518 339 Gene3D G3DSA:3.90.640.10 183 255 2.6E-128 T 11-10-2018 UP12_05170 cc00df15b3d55d60818e04bd546f0218 769 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 558 759 7.8E-72 T 11-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal UP12_05170 cc00df15b3d55d60818e04bd546f0218 769 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 7 170 7.7E-62 T 11-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal UP12_05170 cc00df15b3d55d60818e04bd546f0218 769 Pfam PF12698 ABC-2 family transporter protein 402 753 2.5E-16 T 11-10-2018 UP12_05170 cc00df15b3d55d60818e04bd546f0218 769 Pfam PF12698 ABC-2 family transporter protein 23 155 1.5E-14 T 11-10-2018 UP12_05170 cc00df15b3d55d60818e04bd546f0218 769 Gene3D G3DSA:1.10.287.950 176 361 1.4E-5 T 11-10-2018 UP12_18330 fe06d018f9d0c85fc141081724ae2bc2 218 Gene3D G3DSA:3.40.50.880 1 218 2.9E-72 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_18330 fe06d018f9d0c85fc141081724ae2bc2 218 Pfam PF01965 DJ-1/PfpI family 26 215 1.3E-12 T 11-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UP12_18330 fe06d018f9d0c85fc141081724ae2bc2 218 SUPERFAMILY SSF52317 2 217 1.54E-62 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_12535 4e1669d53564d6e8b2cfd6cf485a2780 146 SUPERFAMILY SSF46785 11 144 2.4E-31 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_12535 4e1669d53564d6e8b2cfd6cf485a2780 146 Gene3D G3DSA:1.10.10.10 2 146 4.1E-37 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_12535 4e1669d53564d6e8b2cfd6cf485a2780 146 Pfam PF01047 MarR family 36 94 1.4E-19 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_12535 4e1669d53564d6e8b2cfd6cf485a2780 146 SMART SM00347 29 129 4.5E-25 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_12535 4e1669d53564d6e8b2cfd6cf485a2780 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 7.7E-9 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_12535 4e1669d53564d6e8b2cfd6cf485a2780 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 7.7E-9 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_12535 4e1669d53564d6e8b2cfd6cf485a2780 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 7.7E-9 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 Hamap MF_00965 ATP-dependent RNA helicase DbpA [dbpA]. 6 479 66.373 T 11-10-2018 IPR028619 ATP-dependent RNA helicase DbpA GO:0000027|GO:0003724 UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 Gene3D G3DSA:3.40.50.300 210 367 8.8E-48 T 11-10-2018 UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 SMART SM00490 256 337 3.9E-31 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 Pfam PF00270 DEAD/DEAH box helicase 28 194 6.7E-44 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 Gene3D G3DSA:3.30.70.330 405 480 3.2E-28 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 SMART SM00487 23 220 1.5E-55 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 SUPERFAMILY SSF52540 71 350 1.56E-69 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 11-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 Pfam PF03880 DbpA RNA binding domain 406 476 1.7E-18 T 11-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 Pfam PF00271 Helicase conserved C-terminal domain 235 337 1.3E-29 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_13235 717ccea54d68dc3afa19730efa71ce4a 480 Gene3D G3DSA:3.40.50.300 4 209 4.7E-70 T 11-10-2018 UP12_15180 1993b777c36e8998eda314259467ea0f 310 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 90 101 - T 11-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 UP12_15180 1993b777c36e8998eda314259467ea0f 310 Gene3D G3DSA:3.30.230.10 6 165 9.7E-44 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_15180 1993b777c36e8998eda314259467ea0f 310 TIGRFAM TIGR00191 thrB: homoserine kinase 8 299 1.8E-96 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UP12_15180 1993b777c36e8998eda314259467ea0f 310 Hamap MF_00384 Homoserine kinase [thrB]. 10 299 29.27 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UP12_15180 1993b777c36e8998eda314259467ea0f 310 SUPERFAMILY SSF54211 6 151 4.93E-31 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_15180 1993b777c36e8998eda314259467ea0f 310 Gene3D G3DSA:3.30.70.890 166 288 3.3E-35 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UP12_15180 1993b777c36e8998eda314259467ea0f 310 SUPERFAMILY SSF55060 164 284 3.45E-33 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UP12_15180 1993b777c36e8998eda314259467ea0f 310 PIRSF PIRSF000676 4 301 7.7E-90 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 UP12_15180 1993b777c36e8998eda314259467ea0f 310 Pfam PF08544 GHMP kinases C terminal 205 282 1.2E-9 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain UP12_15180 1993b777c36e8998eda314259467ea0f 310 PRINTS PR00958 Homoserine kinase signature 131 144 7.3E-40 T 11-10-2018 UP12_15180 1993b777c36e8998eda314259467ea0f 310 PRINTS PR00958 Homoserine kinase signature 249 264 7.3E-40 T 11-10-2018 UP12_15180 1993b777c36e8998eda314259467ea0f 310 PRINTS PR00958 Homoserine kinase signature 97 112 7.3E-40 T 11-10-2018 UP12_15180 1993b777c36e8998eda314259467ea0f 310 PRINTS PR00958 Homoserine kinase signature 169 186 7.3E-40 T 11-10-2018 UP12_15180 1993b777c36e8998eda314259467ea0f 310 PRINTS PR00958 Homoserine kinase signature 15 30 7.3E-40 T 11-10-2018 UP12_15180 1993b777c36e8998eda314259467ea0f 310 Pfam PF00288 GHMP kinases N terminal domain 84 144 6.2E-12 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 38 57 - T 11-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 237 257 - T 11-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 Gene3D G3DSA:3.20.20.70 1 302 3.7E-101 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 Pfam PF01180 Dihydroorotate dehydrogenase 1 284 1.2E-94 T 11-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 PIRSF PIRSF000164 1 301 4.5E-85 T 11-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 SUPERFAMILY SSF51395 2 300 1.7E-88 T 11-10-2018 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 2 299 42.182 T 11-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 UP12_07565 da98d025e44c5edda829c676ee58fedc 310 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 2 300 8.7E-132 T 11-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 UP12_19175 fb5f68d1fa08d81c00d5cd8b899a1a3e 263 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 7 250 33.409 T 11-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 UP12_19175 fb5f68d1fa08d81c00d5cd8b899a1a3e 263 Pfam PF02096 60Kd inner membrane protein 64 246 3.5E-61 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_19175 fb5f68d1fa08d81c00d5cd8b899a1a3e 263 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 63 246 3.4E-67 T 11-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19175 fb5f68d1fa08d81c00d5cd8b899a1a3e 263 PRINTS PR00701 60kDa inner membrane protein signature 213 236 3.1E-15 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_19175 fb5f68d1fa08d81c00d5cd8b899a1a3e 263 PRINTS PR00701 60kDa inner membrane protein signature 129 152 3.1E-15 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_19175 fb5f68d1fa08d81c00d5cd8b899a1a3e 263 PRINTS PR01900 YidC translocation/secretion protein signature 180 195 9.1E-6 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_19175 fb5f68d1fa08d81c00d5cd8b899a1a3e 263 PRINTS PR01900 YidC translocation/secretion protein signature 202 226 9.1E-6 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_16545 1631afe969f83a2ec4a87e59b1d97816 144 SUPERFAMILY SSF141457 1 138 7.59E-49 T 11-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily UP12_16545 1631afe969f83a2ec4a87e59b1d97816 144 Pfam PF02623 FliW protein 19 137 6.4E-39 T 11-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 UP12_16545 1631afe969f83a2ec4a87e59b1d97816 144 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 141 25.669 T 11-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 UP12_16545 1631afe969f83a2ec4a87e59b1d97816 144 Gene3D G3DSA:2.30.290.10 1 143 2.8E-52 T 11-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 Gene3D G3DSA:3.40.50.720 134 336 1.0E-152 T 11-10-2018 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 SUPERFAMILY SSF53223 4 143 2.14E-49 T 11-10-2018 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 11-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.3E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.3E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.3E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.3E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 SUPERFAMILY SSF51735 141 348 1.75E-56 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 130 9.4E-28 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 PIRSF PIRSF000188 1 353 3.3E-167 T 11-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 8.9E-7 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 217 313 1.1E-8 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 SMART SM00839 144 351 4.4E-71 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 UP12_10905 bfb0ff94968fedfdde409d969e52880e 364 Gene3D G3DSA:3.40.50.10860 10 343 1.0E-152 T 11-10-2018 UP12_14965 5fa1cfa09930c4685a482d34ce8c17d8 771 Pfam PF07730 Histidine kinase 570 638 1.3E-11 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UP12_14965 5fa1cfa09930c4685a482d34ce8c17d8 771 SUPERFAMILY SSF50156 44 104 3.85E-6 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_14965 5fa1cfa09930c4685a482d34ce8c17d8 771 Gene3D G3DSA:3.30.565.10 636 771 9.2E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_14965 5fa1cfa09930c4685a482d34ce8c17d8 771 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 682 769 4.1E-7 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_14965 5fa1cfa09930c4685a482d34ce8c17d8 771 SUPERFAMILY SSF55874 662 768 4.85E-18 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_14965 5fa1cfa09930c4685a482d34ce8c17d8 771 Gene3D G3DSA:2.30.42.10 5 100 1.9E-6 T 11-10-2018 UP12_14965 5fa1cfa09930c4685a482d34ce8c17d8 771 SMART SM00387 678 771 5.1E-6 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_12005 00a695ab71763d838d96976bf66ac2ab 217 SUPERFAMILY SSF161098 13 199 3.01E-46 T 11-10-2018 IPR035906 MetI-like superfamily UP12_12005 00a695ab71763d838d96976bf66ac2ab 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 1.1E-27 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_12005 00a695ab71763d838d96976bf66ac2ab 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 214 4.8E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_12005 00a695ab71763d838d96976bf66ac2ab 217 Gene3D G3DSA:1.10.3720.10 1 216 4.1E-55 T 11-10-2018 IPR035906 MetI-like superfamily UP12_17565 ead6c7d07996133b8f51b5eccfb7b5b1 291 Gene3D G3DSA:1.10.1040.10 174 290 4.6E-24 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_17565 ead6c7d07996133b8f51b5eccfb7b5b1 291 Pfam PF09130 Domain of unknown function (DUF1932) 195 263 2.8E-12 T 11-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal UP12_17565 ead6c7d07996133b8f51b5eccfb7b5b1 291 SUPERFAMILY SSF48179 166 269 8.84E-22 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_17565 ead6c7d07996133b8f51b5eccfb7b5b1 291 Gene3D G3DSA:3.40.50.720 2 172 7.9E-36 T 11-10-2018 UP12_17565 ead6c7d07996133b8f51b5eccfb7b5b1 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 127 3.6E-12 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 UP12_17565 ead6c7d07996133b8f51b5eccfb7b5b1 291 SUPERFAMILY SSF51735 1 163 1.34E-28 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13450 a502d5a67ae015ccd956c37dd75fead0 201 SUPERFAMILY SSF50249 92 199 6.43E-33 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_13450 a502d5a67ae015ccd956c37dd75fead0 201 Pfam PF01588 Putative tRNA binding domain 96 197 9.3E-27 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 UP12_13450 a502d5a67ae015ccd956c37dd75fead0 201 Gene3D G3DSA:2.40.50.140 5 199 6.1E-74 T 11-10-2018 UP12_13450 a502d5a67ae015ccd956c37dd75fead0 201 Pfam PF14794 Domain of unknown function (DUF4479) 23 91 1.2E-25 T 11-10-2018 IPR027855 Domain of unknown function DUF4479 UP12_13450 a502d5a67ae015ccd956c37dd75fead0 201 Gene3D G3DSA:3.30.1940.10 18 92 6.1E-74 T 11-10-2018 IPR037154 YtpR-like superfamily UP12_16830 15c3f6758adb8d871679b9daf1a64527 465 Pfam PF13489 Methyltransferase domain 258 401 1.9E-18 T 11-10-2018 UP12_16830 15c3f6758adb8d871679b9daf1a64527 465 Pfam PF00535 Glycosyl transferase family 2 6 125 4.8E-27 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_16830 15c3f6758adb8d871679b9daf1a64527 465 Gene3D G3DSA:3.40.50.150 253 460 8.3E-41 T 11-10-2018 UP12_16830 15c3f6758adb8d871679b9daf1a64527 465 SUPERFAMILY SSF53448 4 251 1.8E-55 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_16830 15c3f6758adb8d871679b9daf1a64527 465 Gene3D G3DSA:3.90.550.10 1 226 1.0E-54 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_16830 15c3f6758adb8d871679b9daf1a64527 465 SUPERFAMILY SSF53335 251 418 7.84E-31 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Gene3D G3DSA:3.60.20.10 22 555 0.0 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 SUPERFAMILY SSF69336 1217 1483 2.62E-90 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Gene3D G3DSA:2.160.20.60 1219 1493 2.1E-107 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 SUPERFAMILY SSF56235 22 443 1.26E-149 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Pfam PF01645 Conserved region in glutamate synthase 802 1169 8.4E-162 T 11-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Pfam PF00310 Glutamine amidotransferases class-II 22 440 1.5E-183 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Pfam PF01493 GXGXG motif 1248 1436 7.4E-80 T 11-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Pfam PF04898 Glutamate synthase central domain 467 744 1.9E-113 T 11-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Gene3D G3DSA:3.20.20.70 493 1186 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 SUPERFAMILY SSF51395 463 1207 2.81E-257 T 11-10-2018 UP12_09295 426168fa60bb30c7e4d721a76d5f7f3c 1523 Gene3D G3DSA:3.20.20.70 445 801 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_07925 86ad582b34a5306d6ba71953d3151d2c 440 Gene3D G3DSA:3.30.750.140 285 414 4.0E-10 T 11-10-2018 IPR038610 FliK-like, C-terminal domain superfamily UP12_07925 86ad582b34a5306d6ba71953d3151d2c 440 Pfam PF02120 Flagellar hook-length control protein FliK 319 393 1.9E-18 T 11-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal UP12_02575 de373572d4982306790bcb49f24b700d 162 SMART SM00387 38 152 0.0081 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_02575 de373572d4982306790bcb49f24b700d 162 Gene3D G3DSA:3.30.565.10 5 156 4.3E-26 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02575 de373572d4982306790bcb49f24b700d 162 Hamap MF_00638 Serine-protein kinase RsbW [rsbW]. 2 158 39.128 T 11-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 UP12_02575 de373572d4982306790bcb49f24b700d 162 SUPERFAMILY SSF55874 31 137 8.38E-15 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02575 de373572d4982306790bcb49f24b700d 162 TIGRFAM TIGR01924 rsbW_low_gc: anti-sigma B factor 1 161 2.3E-78 T 11-10-2018 IPR010193 Serine-protein kinase RsbW GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 UP12_02575 de373572d4982306790bcb49f24b700d 162 Pfam PF13581 Histidine kinase-like ATPase domain 12 143 1.4E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 6.9E-16 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 6.9E-16 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 6.9E-16 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 6.9E-16 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 SUPERFAMILY SSF46785 7 134 2.19E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 Pfam PF01047 MarR family 32 88 9.6E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 SMART SM00347 24 124 7.8E-22 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 ProSitePatterns PS01117 MarR-type HTH domain signature. 63 97 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UP12_08915 7ef48b1454e85931a5ead69f4e037cbd 141 Gene3D G3DSA:1.10.10.10 1 136 1.7E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04345 45ee593d98234fc2f8e7951a69fde2a8 200 Pfam PF04545 Sigma-70, region 4 132 179 4.4E-13 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_04345 45ee593d98234fc2f8e7951a69fde2a8 200 SUPERFAMILY SSF88659 118 179 1.59E-16 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_04345 45ee593d98234fc2f8e7951a69fde2a8 200 Gene3D G3DSA:1.20.140.160 25 182 1.1E-14 T 11-10-2018 UP12_04345 45ee593d98234fc2f8e7951a69fde2a8 200 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 180 5.1E-13 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_08435 c62d1591da7d694e82eba98712bfa031 318 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 293 1.2E-115 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UP12_08435 c62d1591da7d694e82eba98712bfa031 318 Gene3D G3DSA:1.10.20.140 115 187 1.2E-106 T 11-10-2018 UP12_08435 c62d1591da7d694e82eba98712bfa031 318 SUPERFAMILY SSF52540 8 164 1.14E-19 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08435 c62d1591da7d694e82eba98712bfa031 318 Pfam PF01715 IPP transferase 41 285 2.2E-86 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UP12_08435 c62d1591da7d694e82eba98712bfa031 318 SUPERFAMILY SSF52540 6 267 3.33E-9 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08435 c62d1591da7d694e82eba98712bfa031 318 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 309 30.787 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 UP12_08435 c62d1591da7d694e82eba98712bfa031 318 Gene3D G3DSA:3.40.50.300 12 290 1.2E-106 T 11-10-2018 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 Gene3D G3DSA:1.10.238.260 279 390 2.7E-39 T 11-10-2018 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 498 3.5E-240 T 11-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 SUPERFAMILY SSF51569 2 290 5.62E-95 T 11-10-2018 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 42.584 T 11-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 Gene3D G3DSA:3.30.160.270 391 501 5.6E-11 T 11-10-2018 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 Pfam PF08502 LeuA allosteric (dimerisation) domain 368 500 1.3E-36 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 SMART SM00917 368 501 1.1E-35 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 Gene3D G3DSA:3.20.20.70 1 275 5.5E-114 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 SUPERFAMILY SSF110921 396 500 1.83E-19 T 11-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 UP12_12415 ae3b4b1c21fffd50eee876893ec51af2 517 Pfam PF00682 HMGL-like 3 272 2.9E-94 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 269 780 1.1E-93 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Gene3D G3DSA:3.30.70.100 72 138 2.0E-20 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 SUPERFAMILY SSF55008 70 137 3.93E-20 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Pfam PF00702 haloacid dehalogenase-like hydrolase 495 711 1.8E-46 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 229 799 3.7E-198 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 211 800 2.4E-185 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 SUPERFAMILY SSF55008 3 71 2.09E-19 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Pfam PF00403 Heavy-metal-associated domain 7 67 2.0E-15 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Pfam PF00403 Heavy-metal-associated domain 75 134 6.6E-14 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Gene3D G3DSA:3.40.50.1000 479 749 4.9E-94 T 11-10-2018 IPR023214 HAD superfamily UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Gene3D G3DSA:3.30.70.100 2 71 2.7E-21 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 SUPERFAMILY SSF81665 258 765 8.63E-13 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 192 212 6.8E-16 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 212 237 6.8E-16 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00942 Copper-transporting ATPase 1 signature 4 29 6.8E-16 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 ProSitePatterns PS01047 Heavy-metal-associated domain. 77 106 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Gene3D G3DSA:3.40.1110.10 509 629 4.9E-94 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 500 506 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 SUPERFAMILY SSF81653 300 396 4.84E-28 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 498 512 8.0E-28 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 346 360 8.0E-28 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 654 8.0E-28 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 697 716 8.0E-28 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 633 8.0E-28 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 720 732 8.0E-28 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Pfam PF00122 E1-E2 ATPase 297 477 5.4E-57 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 SUPERFAMILY SSF56784 496 797 3.41E-64 T 11-10-2018 IPR036412 HAD-like superfamily UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 Gene3D G3DSA:2.70.150.20 289 401 3.8E-41 T 11-10-2018 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 72 136 1.7E-11 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 UP12_15765 1a27e4c91dd65966d8dc22623e58495c 811 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 69 1.7E-11 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 Gene3D G3DSA:3.40.50.620 1 331 3.3E-144 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 SUPERFAMILY SSF48163 298 482 7.59E-50 T 11-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 SUPERFAMILY SSF52374 5 316 4.02E-113 T 11-10-2018 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 323 3.1E-127 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 1.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 204 1.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 218 1.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 1.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 1.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 482 3.3E-202 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 483 33.809 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 Gene3D G3DSA:1.10.10.350 390 483 3.5E-34 T 11-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 UP12_00610 6c53373ff7c2b4f8213399ea4f41ba2c 483 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 PIRSF PIRSF001365 1 265 2.4E-43 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 SUPERFAMILY SSF51569 4 264 2.2E-51 T 11-10-2018 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 SMART SM01130 1 265 3.9E-22 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 2.8E-13 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 2.8E-13 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.8E-13 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 2.8E-13 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 Gene3D G3DSA:3.20.20.70 1 265 8.0E-57 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_05975 f519739dc022a97eff36f6f7750c0dc1 265 Pfam PF00701 Dihydrodipicolinate synthetase family 2 264 2.1E-42 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_07030 5a429dd970749706455e30ab38f28066 555 Gene3D G3DSA:3.40.50.10710 207 357 2.0E-194 T 11-10-2018 UP12_07030 5a429dd970749706455e30ab38f28066 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 48.026 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UP12_07030 5a429dd970749706455e30ab38f28066 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 5.0E-15 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_07030 5a429dd970749706455e30ab38f28066 555 PIRSF PIRSF004803 1 555 3.7E-248 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UP12_07030 5a429dd970749706455e30ab38f28066 555 Gene3D G3DSA:3.10.20.580 449 555 1.7E-39 T 11-10-2018 UP12_07030 5a429dd970749706455e30ab38f28066 555 Gene3D G3DSA:3.60.15.10 12 442 2.0E-194 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_07030 5a429dd970749706455e30ab38f28066 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 407 2.8E-8 T 11-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain UP12_07030 5a429dd970749706455e30ab38f28066 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 3.9E-236 T 11-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 UP12_07030 5a429dd970749706455e30ab38f28066 555 SMART SM00849 21 215 1.2E-24 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_07030 5a429dd970749706455e30ab38f28066 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 11-10-2018 IPR001587 Ribonuclease J, conserved site UP12_07030 5a429dd970749706455e30ab38f28066 555 SUPERFAMILY SSF56281 11 423 4.9E-95 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_00400 a425a5215c9d36f76a0c2a98cc290ee8 244 Pfam PF13519 von Willebrand factor type A domain 135 227 5.9E-7 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_00400 a425a5215c9d36f76a0c2a98cc290ee8 244 SUPERFAMILY SSF53300 133 227 1.18E-11 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_00400 a425a5215c9d36f76a0c2a98cc290ee8 244 Gene3D G3DSA:3.40.50.410 1 240 5.5E-57 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_00400 a425a5215c9d36f76a0c2a98cc290ee8 244 Pfam PF00092 von Willebrand factor type A domain 1 78 3.5E-7 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_00400 a425a5215c9d36f76a0c2a98cc290ee8 244 SUPERFAMILY SSF53300 2 76 3.12E-10 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 Pfam PF00005 ABC transporter 297 441 1.3E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 Gene3D G3DSA:3.40.50.300 2 263 1.1E-59 T 11-10-2018 UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 Gene3D G3DSA:3.40.50.300 276 528 2.3E-64 T 11-10-2018 UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 SMART SM00382 305 490 1.3E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 SMART SM00382 31 209 3.2E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 SUPERFAMILY SSF52540 5 221 5.09E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 SUPERFAMILY SSF52540 267 510 5.95E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18310 4ce10dfa23dd99169db2b453395e50e4 532 Pfam PF00005 ABC transporter 22 160 9.1E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_14990 b7174761cf07a8858765c0e39ca63805 489 SUPERFAMILY SSF51690 141 480 1.37E-130 T 11-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UP12_14990 b7174761cf07a8858765c0e39ca63805 489 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 159 347 2.1E-13 T 11-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 UP12_14990 b7174761cf07a8858765c0e39ca63805 489 PIRSF PIRSF000484 6 481 1.7E-151 T 11-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 UP12_14990 b7174761cf07a8858765c0e39ca63805 489 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 11 466 7.0E-177 T 11-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 UP12_14990 b7174761cf07a8858765c0e39ca63805 489 Gene3D G3DSA:3.20.140.10 12 471 6.7E-204 T 11-10-2018 UP12_14990 b7174761cf07a8858765c0e39ca63805 489 SUPERFAMILY SSF54675 9 140 2.5E-48 T 11-10-2018 UP12_14990 b7174761cf07a8858765c0e39ca63805 489 Gene3D G3DSA:3.20.20.70 153 320 6.7E-204 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_14935 50699153546b1286f3224ec7a97f4df2 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 4.1E-16 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_14935 50699153546b1286f3224ec7a97f4df2 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 4.1E-16 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_14935 50699153546b1286f3224ec7a97f4df2 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 4.1E-16 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_14935 50699153546b1286f3224ec7a97f4df2 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 4.1E-16 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_14935 50699153546b1286f3224ec7a97f4df2 492 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 4.1E-16 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_14935 50699153546b1286f3224ec7a97f4df2 492 Pfam PF00361 Proton-conducting membrane transporter 128 414 4.1E-50 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_11340 03ffa40188f79bd0f2387eb552916bd1 181 Pfam PF13302 Acetyltransferase (GNAT) domain 8 152 1.3E-23 T 11-10-2018 IPR000182 GNAT domain UP12_11340 03ffa40188f79bd0f2387eb552916bd1 181 Gene3D G3DSA:3.40.630.30 4 179 1.4E-47 T 11-10-2018 UP12_11340 03ffa40188f79bd0f2387eb552916bd1 181 SUPERFAMILY SSF55729 5 176 9.19E-43 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_10970 7c86ce41cbca229340cfd648e1c2107e 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 82 98 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site UP12_10970 7c86ce41cbca229340cfd648e1c2107e 296 Pfam PF00348 Polyprenyl synthetase 32 273 1.3E-59 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 UP12_10970 7c86ce41cbca229340cfd648e1c2107e 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site UP12_10970 7c86ce41cbca229340cfd648e1c2107e 296 SUPERFAMILY SSF48576 7 285 4.32E-85 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_10970 7c86ce41cbca229340cfd648e1c2107e 296 Gene3D G3DSA:1.10.600.10 1 296 9.7E-105 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1180 24.924 T 11-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 PIRSF PIRSF005719 1 1186 0.0 T 11-10-2018 IPR024704 Structural maintenance of chromosomes protein UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 Gene3D G3DSA:3.40.50.300 967 1186 1.4E-55 T 11-10-2018 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 Gene3D G3DSA:3.40.50.300 1 244 3.4E-60 T 11-10-2018 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 SMART SM00968 518 637 1.0E-39 T 11-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 Gene3D G3DSA:3.30.70.1620 578 667 6.9E-68 T 11-10-2018 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 SUPERFAMILY SSF75553 484 686 1.57E-57 T 11-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1178 0.0 T 11-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 SUPERFAMILY SSF52540 1 1180 6.83E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 SUPERFAMILY SSF52540 1 481 2.26E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1171 1.0E-65 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 637 1.3E-29 T 11-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 UP12_07765 a57f67cf78ba8a421328154821f17d41 1186 Gene3D G3DSA:1.20.1060.20 495 679 6.9E-68 T 11-10-2018 UP12_10910 bfc9e532e8982a989dcbad9d1c1885f4 297 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 3 296 1.1E-130 T 11-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 UP12_10910 bfc9e532e8982a989dcbad9d1c1885f4 297 SUPERFAMILY SSF53659 3 295 4.93E-65 T 11-10-2018 UP12_10910 bfc9e532e8982a989dcbad9d1c1885f4 297 PIRSF PIRSF000428 1 297 4.1E-84 T 11-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 UP12_10910 bfc9e532e8982a989dcbad9d1c1885f4 297 Pfam PF01515 Phosphate acetyl/butaryl transferase 4 75 7.2E-7 T 11-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 UP12_10910 bfc9e532e8982a989dcbad9d1c1885f4 297 Pfam PF01515 Phosphate acetyl/butaryl transferase 78 293 5.5E-50 T 11-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 UP12_10910 bfc9e532e8982a989dcbad9d1c1885f4 297 Gene3D G3DSA:3.40.718.10 3 296 6.2E-106 T 11-10-2018 UP12_04610 fe9fc686a29aa39fddf4929a037a9d45 248 Pfam PF00005 ABC transporter 19 156 1.5E-22 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04610 fe9fc686a29aa39fddf4929a037a9d45 248 SMART SM00382 27 205 5.9E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04610 fe9fc686a29aa39fddf4929a037a9d45 248 SUPERFAMILY SSF52540 3 219 7.07E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04610 fe9fc686a29aa39fddf4929a037a9d45 248 Gene3D G3DSA:3.40.50.300 1 237 1.7E-50 T 11-10-2018 UP12_07860 32985b4292e49f1a861c464a6d169a64 305 Gene3D G3DSA:1.10.443.10 112 295 1.8E-60 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UP12_07860 32985b4292e49f1a861c464a6d169a64 305 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 91 4.1E-20 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UP12_07860 32985b4292e49f1a861c464a6d169a64 305 Pfam PF00589 Phage integrase family 113 287 2.8E-51 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UP12_07860 32985b4292e49f1a861c464a6d169a64 305 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 302 3.5E-107 T 11-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 UP12_07860 32985b4292e49f1a861c464a6d169a64 305 Gene3D G3DSA:1.10.150.130 4 99 1.3E-22 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal UP12_07860 32985b4292e49f1a861c464a6d169a64 305 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 301 54.734 T 11-10-2018 IPR023009 Tyrosine recombinase XerC/XerD UP12_07860 32985b4292e49f1a861c464a6d169a64 305 SUPERFAMILY SSF56349 9 295 8.83E-57 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UP12_12850 4b253723c050b6cccbffac76efffec5a 492 SUPERFAMILY SSF51011 361 489 7.55E-28 T 11-10-2018 UP12_12850 4b253723c050b6cccbffac76efffec5a 492 SMART SM00813 293 483 1.1E-73 T 11-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UP12_12850 4b253723c050b6cccbffac76efffec5a 492 Gene3D G3DSA:2.60.40.1180 11 487 3.4E-196 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta UP12_12850 4b253723c050b6cccbffac76efffec5a 492 Gene3D G3DSA:3.20.20.80 15 375 3.4E-196 T 11-10-2018 UP12_12850 4b253723c050b6cccbffac76efffec5a 492 SUPERFAMILY SSF51445 14 375 5.43E-98 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_12850 4b253723c050b6cccbffac76efffec5a 492 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 293 483 1.6E-41 T 11-10-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Gene3D G3DSA:1.10.287.380 807 879 8.0E-24 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 4.2E-23 T 11-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 SUPERFAMILY SSF47323 577 829 1.31E-78 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 SUPERFAMILY SSF46589 814 878 1.31E-16 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 SUPERFAMILY SSF50677 197 347 9.42E-65 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Gene3D G3DSA:1.10.730.10 8 741 0.0 T 11-10-2018 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 SUPERFAMILY SSF52374 7 575 2.82E-146 T 11-10-2018 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Hamap MF_02004 Valine--tRNA ligase [valS]. 8 879 16.304 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 TIGRFAM TIGR00422 valS: valine--tRNA ligase 8 861 0.0 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Pfam PF08264 Anticodon-binding domain of tRNA 608 756 7.2E-45 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 565 3.8E-227 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Gene3D G3DSA:3.40.50.620 28 526 0.0 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 351 364 8.7E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 8.7E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 445 466 8.7E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 8.7E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 PRINTS PR00986 Valyl-tRNA synthetase signature 477 495 8.7E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 UP12_12315 7d75f44a0b323facd8195558fc45af5d 880 Gene3D G3DSA:3.90.740.10 181 347 0.0 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 UP12_02430 a5879acfca965a9e248fe28caa22b365 276 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 10 262 8.0E-74 T 11-10-2018 UP12_02430 a5879acfca965a9e248fe28caa22b365 276 Pfam PF12787 EcsC protein family 9 259 3.4E-81 T 11-10-2018 IPR024787 EcsC protein UP12_00090 acae25c3284040f59e14dc9a251d8fc7 196 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 4 185 2.7E-79 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00090 acae25c3284040f59e14dc9a251d8fc7 196 Pfam PF01174 SNO glutamine amidotransferase family 6 188 1.3E-74 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00090 acae25c3284040f59e14dc9a251d8fc7 196 Gene3D G3DSA:3.40.50.880 1 196 1.3E-70 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_00090 acae25c3284040f59e14dc9a251d8fc7 196 SUPERFAMILY SSF52317 3 189 8.62E-53 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_00090 acae25c3284040f59e14dc9a251d8fc7 196 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 36.28 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00090 acae25c3284040f59e14dc9a251d8fc7 196 PIRSF PIRSF005639 1 191 3.5E-71 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_00090 acae25c3284040f59e14dc9a251d8fc7 196 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 11-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 UP12_11380 3cbd7d71136bcb761991a5a6b2d9fe12 258 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_11380 3cbd7d71136bcb761991a5a6b2d9fe12 258 Gene3D G3DSA:3.40.50.300 1 253 9.5E-64 T 11-10-2018 UP12_11380 3cbd7d71136bcb761991a5a6b2d9fe12 258 SMART SM00382 30 219 5.9E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_11380 3cbd7d71136bcb761991a5a6b2d9fe12 258 Pfam PF00005 ABC transporter 22 169 1.6E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_11380 3cbd7d71136bcb761991a5a6b2d9fe12 258 SUPERFAMILY SSF52540 3 217 8.78E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 SMART SM01382 124 253 4.1E-94 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 49.912 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 Gene3D G3DSA:2.30.30.30 118 196 1.2E-35 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 SUPERFAMILY SSF50249 2 125 1.54E-51 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 Gene3D G3DSA:4.10.950.10 197 276 3.0E-35 T 11-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 PIRSF PIRSF002158 3 276 2.1E-100 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 5.9E-58 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 7.0E-34 T 11-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 6.2E-141 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 Gene3D G3DSA:2.40.50.140 1 114 9.8E-50 T 11-10-2018 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 SMART SM01383 42 118 1.3E-47 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 11-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00740 4137ac86c67bcf9ddd261fc83111f6a9 277 SUPERFAMILY SSF50104 126 273 2.59E-61 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily UP12_05820 ff4cbf67ba2b332918e8d97bbe4c0c08 370 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 7 349 1.2E-102 T 11-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 UP12_05820 ff4cbf67ba2b332918e8d97bbe4c0c08 370 Pfam PF01266 FAD dependent oxidoreductase 6 346 1.8E-63 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 UP12_05820 ff4cbf67ba2b332918e8d97bbe4c0c08 370 SUPERFAMILY SSF54373 220 306 2.49E-19 T 11-10-2018 UP12_05820 ff4cbf67ba2b332918e8d97bbe4c0c08 370 Gene3D G3DSA:3.30.9.10 93 306 1.6E-112 T 11-10-2018 UP12_05820 ff4cbf67ba2b332918e8d97bbe4c0c08 370 Gene3D G3DSA:3.50.50.60 8 347 1.6E-112 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05820 ff4cbf67ba2b332918e8d97bbe4c0c08 370 SUPERFAMILY SSF51905 4 365 1.24E-44 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 11-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 Gene3D G3DSA:3.30.2130.10 289 453 4.5E-53 T 11-10-2018 UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 Gene3D G3DSA:1.20.120.1320 39 135 1.1E-72 T 11-10-2018 UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 SUPERFAMILY SSF55021 376 449 7.44E-19 T 11-10-2018 UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 PIRSF PIRSF000726 1 454 6.5E-72 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 SUPERFAMILY SSF53633 2 290 1.26E-63 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 Gene3D G3DSA:3.40.1160.10 3 287 1.1E-72 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 Pfam PF00696 Amino acid kinase family 2 276 2.6E-36 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 449 2.6E-76 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_02140 cf96dfea676a0d2772292837cd04ca0d 458 SUPERFAMILY SSF55021 296 360 1.74E-7 T 11-10-2018 UP12_18060 23546ee9d69e8ab1d54ced76d9e3cc55 471 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 442 2.7E-171 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UP12_18060 23546ee9d69e8ab1d54ced76d9e3cc55 471 PIRSF PIRSF006446 1 463 1.2E-187 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UP12_13580 132cc2cd29ecf4fc02fbd3e3cc987883 60 Pfam PF10957 Sporulation protein Cse60 2 60 9.5E-36 T 11-10-2018 IPR020296 Sporulation protein Cse60 UP12_13580 132cc2cd29ecf4fc02fbd3e3cc987883 60 ProDom PD052690 CSE60 CYTOSOLIC YTEV LJ928 SPORULATION ORF85 PROPHAGE 1 59 1.0E-19 T 11-10-2018 IPR020296 Sporulation protein Cse60 UP12_01280 1e9d5dcbaa82874cc9939676c051cc36 86 Gene3D G3DSA:1.20.58.1000 1 85 4.2E-23 T 11-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily UP12_01280 1e9d5dcbaa82874cc9939676c051cc36 86 Pfam PF02583 Metal-sensitive transcriptional repressor 4 82 4.5E-24 T 11-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 UP12_12825 a85c5fcb19e908366b6de3031c8f5d0d 202 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 91 192 9.2E-14 T 11-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12825 a85c5fcb19e908366b6de3031c8f5d0d 202 Gene3D G3DSA:1.20.1300.10 2 202 2.9E-48 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12825 a85c5fcb19e908366b6de3031c8f5d0d 202 PIRSF PIRSF000170 1 202 1.0E-103 T 11-10-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute UP12_12825 a85c5fcb19e908366b6de3031c8f5d0d 202 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 6 202 1.7E-61 T 11-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit UP12_12825 a85c5fcb19e908366b6de3031c8f5d0d 202 SUPERFAMILY SSF81343 5 201 7.98E-63 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_06870 70efd746c46a6730a8e52ac778536803 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 4.5E-118 T 11-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 UP12_06870 70efd746c46a6730a8e52ac778536803 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 45.336 T 11-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 UP12_06870 70efd746c46a6730a8e52ac778536803 236 Gene3D G3DSA:2.160.10.10 85 236 3.4E-50 T 11-10-2018 UP12_06870 70efd746c46a6730a8e52ac778536803 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 198 6.8E-8 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_06870 70efd746c46a6730a8e52ac778536803 236 Gene3D G3DSA:3.30.70.250 1 84 1.2E-36 T 11-10-2018 UP12_06870 70efd746c46a6730a8e52ac778536803 236 SUPERFAMILY SSF51161 34 223 1.05E-49 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_06870 70efd746c46a6730a8e52ac778536803 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 1.1E-36 T 11-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 UP12_06870 70efd746c46a6730a8e52ac778536803 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UP12_06870 70efd746c46a6730a8e52ac778536803 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 118 3.5E-4 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_06870 70efd746c46a6730a8e52ac778536803 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 2.4E-10 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 SMART SM00418 3 82 1.5E-27 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 SUPERFAMILY SSF46785 2 71 3.2E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.1E-19 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.1E-19 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.1E-19 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 35 1.1E-19 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 Gene3D G3DSA:1.10.10.10 1 88 1.1E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08835 c0477de03890a0e52ed3f352ba1b84ce 104 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 3.3E-19 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_19065 f64f10543cbe396a27dcdc98278d205b 222 Pfam PF03358 NADPH-dependent FMN reductase 23 150 5.1E-18 T 11-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UP12_19065 f64f10543cbe396a27dcdc98278d205b 222 Gene3D G3DSA:3.40.50.360 17 222 4.2E-67 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_19065 f64f10543cbe396a27dcdc98278d205b 222 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 22 213 4.9E-46 T 11-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 UP12_19065 f64f10543cbe396a27dcdc98278d205b 222 SUPERFAMILY SSF52218 23 216 5.46E-48 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_01970 03a42d7bff4f35d7731293b0ab97d185 691 Pfam PF01968 Hydantoinase/oxoprolinase 205 492 5.4E-89 T 11-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 UP12_01970 03a42d7bff4f35d7731293b0ab97d185 691 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 7 183 1.4E-44 T 11-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 UP12_01970 03a42d7bff4f35d7731293b0ab97d185 691 SUPERFAMILY SSF53067 6 485 5.29E-10 T 11-10-2018 UP12_17675 daf1a9f8b3475519d5747eb967efdf45 392 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 381 8.9E-142 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UP12_17675 daf1a9f8b3475519d5747eb967efdf45 392 Gene3D G3DSA:3.40.640.10 1 257 4.6E-106 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_17675 daf1a9f8b3475519d5747eb967efdf45 392 Gene3D G3DSA:3.90.1150.10 258 391 3.8E-37 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_17675 daf1a9f8b3475519d5747eb967efdf45 392 SUPERFAMILY SSF53383 9 386 4.26E-125 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_17675 daf1a9f8b3475519d5747eb967efdf45 392 PIRSF PIRSF000390 5 389 1.3E-120 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UP12_07440 ec7d8fd20fbbf2b7a75a226f49f990dd 312 Gene3D G3DSA:3.40.50.1360 56 312 1.4E-82 T 11-10-2018 UP12_07440 ec7d8fd20fbbf2b7a75a226f49f990dd 312 Pfam PF04198 Putative sugar-binding domain 65 312 3.2E-71 T 11-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 UP12_07440 ec7d8fd20fbbf2b7a75a226f49f990dd 312 Pfam PF13384 Homeodomain-like domain 8 50 1.4E-5 T 11-10-2018 UP12_07440 ec7d8fd20fbbf2b7a75a226f49f990dd 312 SUPERFAMILY SSF100950 64 312 8.84E-72 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_07440 ec7d8fd20fbbf2b7a75a226f49f990dd 312 Gene3D G3DSA:1.10.10.60 1 53 3.5E-21 T 11-10-2018 UP12_12615 413ad14db59d646b9a9fcdac61442df4 134 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 6 131 3.9E-24 T 11-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component UP12_12615 413ad14db59d646b9a9fcdac61442df4 134 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 11 98 9.5E-8 T 11-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component UP12_09725 c789bd49e1ca48158b78283536a9697e 221 Pfam PF14344 Domain of unknown function (DUF4397) 29 143 6.4E-22 T 11-10-2018 IPR025510 Domain of unknown function DUF4397 UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 6.9E-66 T 11-10-2018 UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 8.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 8.0E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 SUPERFAMILY SSF51735 5 242 1.83E-73 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 Gene3D G3DSA:3.40.50.720 1 247 2.1E-74 T 11-10-2018 UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.7E-30 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-30 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.7E-30 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-30 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.7E-30 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_11850 b1c0ffb3ec1ca5adbd11c19e91c74e8b 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.7E-30 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06280 8e0f03beae66b6ebed51eaa09196e17c 311 Gene3D G3DSA:1.10.3720.10 83 300 6.3E-25 T 11-10-2018 IPR035906 MetI-like superfamily UP12_06280 8e0f03beae66b6ebed51eaa09196e17c 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 302 7.7E-42 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_06280 8e0f03beae66b6ebed51eaa09196e17c 311 SUPERFAMILY SSF161098 88 286 6.67E-23 T 11-10-2018 IPR035906 MetI-like superfamily UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 SUPERFAMILY SSF101386 232 332 5.52E-25 T 11-10-2018 UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 SUPERFAMILY SSF101386 362 464 6.35E-22 T 11-10-2018 UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 255 328 1.4E-28 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 398 458 2.4E-5 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 Gene3D G3DSA:1.10.287.1080 356 490 1.0E-43 T 11-10-2018 UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 Gene3D G3DSA:1.10.287.1080 229 352 7.3E-43 T 11-10-2018 UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 206 1.1E-24 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 Gene3D G3DSA:3.40.1010.10 1 119 1.5E-13 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 SUPERFAMILY SSF53790 3 255 1.0E-32 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 PIRSF PIRSF002845 1 490 8.0E-218 T 11-10-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted UP12_00355 26ad6c44d85d23f0138cb583db7c5ea7 492 TIGRFAM TIGR00444 mazG: MazG family protein 239 486 1.5E-103 T 11-10-2018 IPR011551 NTP pyrophosphohydrolase MazG UP12_06355 8c57144482be3937cefb9c39ab17ecfe 109 Pfam PF00893 Small Multidrug Resistance protein 1 89 4.9E-19 T 11-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UP12_06355 8c57144482be3937cefb9c39ab17ecfe 109 SUPERFAMILY SSF103481 6 100 1.96E-12 T 11-10-2018 UP12_06355 8c57144482be3937cefb9c39ab17ecfe 109 Gene3D G3DSA:1.10.3730.20 1 104 1.8E-20 T 11-10-2018 UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 Gene3D G3DSA:1.10.3730.10 162 262 6.7E-15 T 11-10-2018 UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 Gene3D G3DSA:3.40.50.720 1 161 4.2E-26 T 11-10-2018 UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 96 1.5E-15 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 260 1.3E-16 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 SUPERFAMILY SSF48179 161 262 1.24E-17 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 PIRSF PIRSF000193 1 266 6.8E-65 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 SUPERFAMILY SSF51735 2 156 5.44E-18 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_11630 cda0479304dcce3230bf0f1c569bc3f9 282 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 SUPERFAMILY SSF51735 6 251 6.5E-86 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 6.4E-72 T 11-10-2018 UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 8.6E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.6E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.6E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 Gene3D G3DSA:3.40.50.720 1 261 5.0E-88 T 11-10-2018 UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.7E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.7E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.7E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.7E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10785 e8ed0bedcda07c1223382b76d3f33ca2 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.7E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 347 43.416 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 202 216 1.2E-31 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 232 248 1.2E-31 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 274 285 1.2E-31 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 164 178 1.2E-31 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 249 266 1.2E-31 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00096 Glutamine amidotransferase superfamily signature 205 214 1.4E-11 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00096 Glutamine amidotransferase superfamily signature 232 243 1.4E-11 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 PRINTS PR00096 Glutamine amidotransferase superfamily signature 318 331 1.4E-11 T 11-10-2018 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 Pfam PF00117 Glutamine amidotransferase class-I 166 341 2.4E-45 T 11-10-2018 IPR017926 Glutamine amidotransferase UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 SMART SM01097 1 130 5.6E-73 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 344 4.7E-136 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 Gene3D G3DSA:3.50.30.20 1 146 9.7E-52 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 Gene3D G3DSA:3.40.50.880 164 342 5.4E-35 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 SUPERFAMILY SSF52021 1 139 4.32E-49 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 129 9.0E-49 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_05585 8b09ef13a2165bc22d34f4e9cc4496be 353 SUPERFAMILY SSF52317 143 345 8.98E-52 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 SUPERFAMILY SSF55021 249 325 2.02E-15 T 11-10-2018 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 Gene3D G3DSA:3.30.70.260 260 337 2.7E-49 T 11-10-2018 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 Gene3D G3DSA:3.40.1160.10 1 253 6.7E-91 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 SUPERFAMILY SSF55021 329 404 2.55E-22 T 11-10-2018 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 Pfam PF13840 ACT domain 335 398 4.8E-15 T 11-10-2018 IPR027795 CASTOR, ACT domain UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 7.4E-151 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 Pfam PF00696 Amino acid kinase family 3 229 5.1E-53 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 SUPERFAMILY SSF53633 4 242 5.63E-72 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 Gene3D G3DSA:3.30.70.260 254 402 2.7E-49 T 11-10-2018 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 PIRSF PIRSF000726 55 408 2.2E-136 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 PIRSF PIRSF000726 1 61 1.3E-21 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 11-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_12835 d32e15ae5ee3c8fca23277b6aa7ef60a 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 400 2.2E-140 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 UP12_16085 7f87008768786c6ef20142e68337973a 328 Pfam PF01032 FecCD transport family 14 322 5.6E-91 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_16085 7f87008768786c6ef20142e68337973a 328 SUPERFAMILY SSF81345 3 322 3.66E-82 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_16085 7f87008768786c6ef20142e68337973a 328 Gene3D G3DSA:1.10.3470.10 2 326 3.2E-92 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_01430 7ed14db20b26bcece87e49fac96f2395 152 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 1 129 7.9E-32 T 11-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 UP12_01430 7ed14db20b26bcece87e49fac96f2395 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 1 144 4.3E-31 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_01430 7ed14db20b26bcece87e49fac96f2395 152 SUPERFAMILY SSF55804 1 144 1.83E-28 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_01430 7ed14db20b26bcece87e49fac96f2395 152 Gene3D G3DSA:3.40.930.10 1 148 3.5E-35 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 SMART SM00287 267 329 4.6E-10 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 SMART SM00287 111 174 2.1E-12 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 SMART SM00287 32 94 3.3E-16 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 SMART SM00287 189 251 1.7E-9 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 SUPERFAMILY SSF53187 351 525 3.14E-51 T 11-10-2018 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 354 522 9.3E-47 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Gene3D G3DSA:3.40.630.40 340 526 4.2E-54 T 11-10-2018 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Gene3D G3DSA:2.30.30.40 25 95 4.4E-16 T 11-10-2018 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Gene3D G3DSA:2.30.30.40 259 330 7.6E-13 T 11-10-2018 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Gene3D G3DSA:2.30.30.40 189 247 3.1E-15 T 11-10-2018 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 SMART SM00646 413 522 6.0E-33 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 PIRSF PIRSF037846 197 526 2.6E-132 T 11-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 PIRSF PIRSF037846 3 261 1.6E-64 T 11-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Pfam PF08239 Bacterial SH3 domain 42 90 1.0E-7 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Pfam PF08239 Bacterial SH3 domain 276 325 2.0E-8 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Pfam PF08239 Bacterial SH3 domain 197 247 5.7E-11 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Pfam PF08239 Bacterial SH3 domain 121 172 7.5E-12 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_12070 c4626e3c6b5173f3badcbeb95727732b 526 Gene3D G3DSA:2.30.30.40 112 178 4.0E-16 T 11-10-2018 UP12_09920 d1536d66b5c58a5e683af5621a9cf7d7 194 Gene3D G3DSA:3.40.50.2020 3 188 3.8E-51 T 11-10-2018 UP12_09920 d1536d66b5c58a5e683af5621a9cf7d7 194 SUPERFAMILY SSF53271 1 188 4.81E-45 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_09920 d1536d66b5c58a5e683af5621a9cf7d7 194 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 191 4.8E-90 T 11-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 UP12_09920 d1536d66b5c58a5e683af5621a9cf7d7 194 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.172 T 11-10-2018 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22 UP12_12590 02e2238c56af39198ba2e52929076067 278 Pfam PF05709 Phage tail protein 30 277 1.4E-32 T 11-10-2018 IPR008841 Siphovirus-type tail component UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 Pfam PF03572 Peptidase family S41 214 375 5.6E-49 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 Gene3D G3DSA:3.30.750.44 61 352 4.6E-91 T 11-10-2018 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 65 396 3.2E-127 T 11-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 SUPERFAMILY SSF52096 53 382 7.12E-70 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 SUPERFAMILY SSF50156 84 206 1.22E-22 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 SUPERFAMILY SSF47090 386 457 2.49E-16 T 11-10-2018 IPR036365 PGBD-like superfamily UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 Gene3D G3DSA:1.10.101.10 387 464 3.3E-15 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 Gene3D G3DSA:2.30.42.10 113 200 4.6E-91 T 11-10-2018 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 Gene3D G3DSA:3.90.226.10 201 374 4.6E-91 T 11-10-2018 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 SMART SM00245 186 377 3.5E-79 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 Pfam PF13180 PDZ domain 114 190 1.6E-12 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 Pfam PF01471 Putative peptidoglycan binding domain 399 454 6.7E-13 T 11-10-2018 IPR002477 Peptidoglycan binding-like UP12_16450 9c113731c2cfbc86e8502d15ed09984e 482 SMART SM00228 113 184 2.1E-15 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_12295 e198c81941911f3b682229782b72112d 189 PIRSF PIRSF006305 1 188 2.1E-60 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 UP12_12295 e198c81941911f3b682229782b72112d 189 SUPERFAMILY SSF52972 2 182 5.75E-61 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UP12_12295 e198c81941911f3b682229782b72112d 189 Gene3D G3DSA:3.90.950.10 1 187 9.0E-75 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like UP12_12295 e198c81941911f3b682229782b72112d 189 Hamap MF_00528 Septum formation protein Maf [maf]. 3 188 31.654 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 UP12_12295 e198c81941911f3b682229782b72112d 189 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 181 5.5E-65 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 UP12_12295 e198c81941911f3b682229782b72112d 189 Pfam PF02545 Maf-like protein 3 183 6.8E-59 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.1E-5 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 168 1.1E-5 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 273 1.1E-5 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 SUPERFAMILY SSF51905 135 301 4.16E-21 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_15155 41084cb1a850423dfa6db815e4f58834 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 3.0E-5 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.0E-5 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 3.0E-5 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 3.0E-5 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 SUPERFAMILY SSF51905 1 182 1.81E-22 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_15155 41084cb1a850423dfa6db815e4f58834 355 Gene3D G3DSA:3.50.50.100 1 354 5.0E-76 T 11-10-2018 UP12_15155 41084cb1a850423dfa6db815e4f58834 355 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 287 9.7E-36 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 PIRSF PIRSF004862 1 530 9.8E-108 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 PRINTS PR01009 Flagellar M-ring protein signature 122 140 3.1E-24 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 PRINTS PR01009 Flagellar M-ring protein signature 269 287 3.1E-24 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 PRINTS PR01009 Flagellar M-ring protein signature 198 216 3.1E-24 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 PRINTS PR01009 Flagellar M-ring protein signature 154 168 3.1E-24 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 PRINTS PR01009 Flagellar M-ring protein signature 348 372 3.1E-24 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 Pfam PF01514 Secretory protein of YscJ/FliF family 31 221 7.1E-62 T 11-10-2018 IPR006182 Secretory protein YscJ/FliF UP12_07895 40a783fdd96f2fb427443330a2612a67 530 Pfam PF08345 Flagellar M-ring protein C-terminal 256 401 1.1E-20 T 11-10-2018 IPR013556 Flagellar M-ring C-terminal UP12_07895 40a783fdd96f2fb427443330a2612a67 530 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 530 2.0E-152 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 UP12_07895 40a783fdd96f2fb427443330a2612a67 530 Gene3D G3DSA:3.30.300.30 133 222 3.8E-8 T 11-10-2018 UP12_01175 bd148c47f707ad05ca6d67e226b8dfe7 123 Gene3D G3DSA:1.10.10.10 10 123 1.5E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01175 bd148c47f707ad05ca6d67e226b8dfe7 123 SMART SM00345 17 76 1.6E-11 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_01175 bd148c47f707ad05ca6d67e226b8dfe7 123 SUPERFAMILY SSF46785 7 85 1.43E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_01175 bd148c47f707ad05ca6d67e226b8dfe7 123 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 3.6E-13 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_16055 1d3c53c19b90f7baa14154837bd9f03c 227 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 27 223 2.9E-60 T 11-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 UP12_16055 1d3c53c19b90f7baa14154837bd9f03c 227 SUPERFAMILY SSF52540 46 217 7.98E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16055 1d3c53c19b90f7baa14154837bd9f03c 227 Gene3D G3DSA:3.40.50.300 1 227 1.6E-69 T 11-10-2018 UP12_16055 1d3c53c19b90f7baa14154837bd9f03c 227 Pfam PF13614 AAA domain 58 176 1.8E-13 T 11-10-2018 IPR025669 AAA domain UP12_19140 a6e783259a5c737e997821039fa86543 253 PRINTS PR00091 Nitrogenase component II signature 31 46 8.7E-5 T 11-10-2018 UP12_19140 a6e783259a5c737e997821039fa86543 253 PRINTS PR00091 Nitrogenase component II signature 9 22 8.7E-5 T 11-10-2018 UP12_19140 a6e783259a5c737e997821039fa86543 253 SUPERFAMILY SSF52540 2 250 6.29E-72 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_19140 a6e783259a5c737e997821039fa86543 253 Pfam PF13614 AAA domain 2 178 6.6E-74 T 11-10-2018 IPR025669 AAA domain UP12_19140 a6e783259a5c737e997821039fa86543 253 PIRSF PIRSF009320 88 250 1.5E-7 T 11-10-2018 UP12_19140 a6e783259a5c737e997821039fa86543 253 PIRSF PIRSF009320 2 84 1.3E-15 T 11-10-2018 UP12_19140 a6e783259a5c737e997821039fa86543 253 Gene3D G3DSA:3.40.50.300 1 252 1.1E-83 T 11-10-2018 UP12_10760 a7ba225f7726148b88916a487842aec3 240 Pfam PF07702 UTRA domain 92 229 3.4E-36 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_10760 a7ba225f7726148b88916a487842aec3 240 Gene3D G3DSA:1.10.10.10 2 70 3.5E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10760 a7ba225f7726148b88916a487842aec3 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 2.7E-15 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_10760 a7ba225f7726148b88916a487842aec3 240 SUPERFAMILY SSF64288 79 232 3.3E-45 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_10760 a7ba225f7726148b88916a487842aec3 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 1.9E-7 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_10760 a7ba225f7726148b88916a487842aec3 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 1.9E-7 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_10760 a7ba225f7726148b88916a487842aec3 240 Gene3D G3DSA:3.40.1410.10 77 233 2.9E-41 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_10760 a7ba225f7726148b88916a487842aec3 240 SUPERFAMILY SSF46785 2 71 5.96E-17 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_10760 a7ba225f7726148b88916a487842aec3 240 SMART SM00345 7 66 1.6E-11 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_10760 a7ba225f7726148b88916a487842aec3 240 SMART SM00866 90 229 1.2E-38 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_08745 2f9c24f94c02920effbcfb25a2205089 48 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 48 19.92 T 11-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 UP12_08745 2f9c24f94c02920effbcfb25a2205089 48 Pfam PF08175 Small acid-soluble spore protein O family 2 48 1.6E-26 T 11-10-2018 UP12_08745 2f9c24f94c02920effbcfb25a2205089 48 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 48 1.8E-25 T 11-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 UP12_08745 2f9c24f94c02920effbcfb25a2205089 48 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 35 1.0E-10 T 11-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 Gene3D G3DSA:2.40.50.530 1 63 2.1E-21 T 11-10-2018 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 8.9E-27 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 SUPERFAMILY SSF143034 2 62 3.14E-22 T 11-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 11-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 4.2E-23 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 4.2E-23 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 4.2E-23 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.267 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 UP12_12960 986cc7039bafd91db92d72f205d6aa96 66 Pfam PF01632 Ribosomal protein L35 2 61 2.6E-25 T 11-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 SUPERFAMILY SSF54999 5 102 6.41E-39 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 7.9E-37 T 11-10-2018 IPR027486 Ribosomal protein S10 domain UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 6.3E-20 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 6.3E-20 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 6.3E-20 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 SMART SM01403 7 101 5.7E-61 T 11-10-2018 IPR027486 Ribosomal protein S10 domain UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.4E-47 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 11-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.352 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00720 e3951e97f9f82491c34b4f58bf503c25 102 Gene3D G3DSA:3.30.70.600 1 102 1.1E-38 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily UP12_17230 04ddfb6c1cadb6e694b018ba15fcd9eb 179 Hamap MF_00800 UPF0340 protein . 1 179 91.742 T 11-10-2018 IPR006340 Protein of unknown function DUF436 UP12_17230 04ddfb6c1cadb6e694b018ba15fcd9eb 179 SUPERFAMILY SSF110710 2 177 2.62E-76 T 11-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like UP12_17230 04ddfb6c1cadb6e694b018ba15fcd9eb 179 Pfam PF04260 Protein of unknown function (DUF436) 8 176 1.5E-78 T 11-10-2018 IPR006340 Protein of unknown function DUF436 UP12_17230 04ddfb6c1cadb6e694b018ba15fcd9eb 179 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 13 176 1.0E-63 T 11-10-2018 IPR006340 Protein of unknown function DUF436 UP12_17230 04ddfb6c1cadb6e694b018ba15fcd9eb 179 PIRSF PIRSF007510 1 179 1.3E-79 T 11-10-2018 IPR006340 Protein of unknown function DUF436 UP12_17230 04ddfb6c1cadb6e694b018ba15fcd9eb 179 Gene3D G3DSA:3.40.50.10360 1 179 1.2E-79 T 11-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like UP12_17230 04ddfb6c1cadb6e694b018ba15fcd9eb 179 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 9 176 3.9E-72 T 11-10-2018 IPR006340 Protein of unknown function DUF436 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 Pfam PF17203 Single cache domain 3 45 175 1.2E-20 T 11-10-2018 IPR033463 Single cache domain 3 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 494 512 8.9E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 531 8.9E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 478 8.9E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 SUPERFAMILY SSF103190 44 174 9.42E-33 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_02440 5f8335467884a49d76463964a5fa9adf 539 Gene3D G3DSA:3.30.565.10 373 533 6.6E-27 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02440 5f8335467884a49d76463964a5fa9adf 539 Gene3D G3DSA:3.30.450.20 206 318 8.7E-24 T 11-10-2018 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 SUPERFAMILY SSF55890 326 377 5.1E-12 T 11-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 Gene3D G3DSA:3.30.450.20 39 169 1.3E-36 T 11-10-2018 UP12_02440 5f8335467884a49d76463964a5fa9adf 539 SMART SM00091 219 284 0.0017 T 11-10-2018 IPR000014 PAS domain UP12_02440 5f8335467884a49d76463964a5fa9adf 539 SUPERFAMILY SSF55874 390 533 2.1E-25 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02440 5f8335467884a49d76463964a5fa9adf 539 SUPERFAMILY SSF55785 218 314 1.33E-8 T 11-10-2018 IPR035965 PAS domain superfamily UP12_02440 5f8335467884a49d76463964a5fa9adf 539 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 531 8.2E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_02440 5f8335467884a49d76463964a5fa9adf 539 SMART SM00387 423 534 1.3E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_02440 5f8335467884a49d76463964a5fa9adf 539 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 325 374 1.5E-9 T 11-10-2018 IPR039506 SpoOB, alpha-helical domain UP12_08180 84a111ae827b1a2aa3373d7feaa11452 90 Pfam PF05239 PRC-barrel domain 2 80 1.9E-16 T 11-10-2018 IPR027275 PRC-barrel domain UP12_08180 84a111ae827b1a2aa3373d7feaa11452 90 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 1.9E-29 T 11-10-2018 IPR014238 Sporulation protein YlmC/YmxH UP12_08180 84a111ae827b1a2aa3373d7feaa11452 90 Gene3D G3DSA:2.30.30.240 2 78 6.7E-9 T 11-10-2018 UP12_08180 84a111ae827b1a2aa3373d7feaa11452 90 SUPERFAMILY SSF50346 2 75 4.08E-12 T 11-10-2018 IPR011033 PRC-barrel-like superfamily UP12_08735 27760681a98c0891219ba9dbc39e403f 133 Gene3D G3DSA:2.60.40.790 30 117 9.5E-10 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_08735 27760681a98c0891219ba9dbc39e403f 133 SUPERFAMILY SSF49764 30 118 4.19E-8 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SMART SM00388 364 431 8.3E-22 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SUPERFAMILY SSF158472 195 242 7.85E-10 T 11-10-2018 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Gene3D G3DSA:1.20.1480.50 155 248 3.6E-18 T 11-10-2018 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Pfam PF00989 PAS fold 253 355 2.1E-9 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SMART SM00387 477 589 1.0E-42 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SUPERFAMILY SSF47384 348 432 2.55E-21 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SUPERFAMILY SSF55874 420 587 2.62E-50 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 532 542 4.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 549 567 4.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 514 528 4.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 586 4.5E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 478 588 6.9E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Gene3D G3DSA:3.30.450.20 249 359 2.3E-13 T 11-10-2018 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SUPERFAMILY SSF55785 241 356 1.05E-10 T 11-10-2018 IPR035965 PAS domain superfamily UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Gene3D G3DSA:3.30.565.10 437 592 1.4E-48 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 431 3.2E-19 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SMART SM00091 253 320 9.3E-7 T 11-10-2018 IPR000014 PAS domain UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Gene3D G3DSA:1.10.287.130 360 436 7.5E-26 T 11-10-2018 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 Pfam PF00672 HAMP domain 195 241 1.1E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_10395 f7b83718270473aa6a1fbb8cd6e26ff2 593 SMART SM00304 194 246 5.3E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 Gene3D G3DSA:1.10.720.90 2 55 1.6E-26 T 11-10-2018 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 5.3E-51 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 SUPERFAMILY SSF74731 2 116 2.09E-50 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.8E-41 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.8E-41 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.8E-41 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 Gene3D G3DSA:1.10.1900.20 56 118 3.7E-29 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 70 1.0E-13 T 11-10-2018 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.092 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12955 272697aa962134901f9cf55fd24e8e81 119 Pfam PF00453 Ribosomal protein L20 3 109 6.0E-50 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_01525 0383c2ed624b69deae1bcaba7cb2a513 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 489 6.7E-15 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_01525 0383c2ed624b69deae1bcaba7cb2a513 502 Pfam PF00501 AMP-binding enzyme 11 405 3.5E-95 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_01525 0383c2ed624b69deae1bcaba7cb2a513 502 Gene3D G3DSA:3.30.300.30 402 501 2.5E-26 T 11-10-2018 UP12_01525 0383c2ed624b69deae1bcaba7cb2a513 502 Gene3D G3DSA:3.40.50.12780 2 401 7.5E-111 T 11-10-2018 UP12_01525 0383c2ed624b69deae1bcaba7cb2a513 502 SUPERFAMILY SSF56801 2 501 2.62E-136 T 11-10-2018 UP12_01525 0383c2ed624b69deae1bcaba7cb2a513 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_18350 be2623d65322275ed77b24271171eef6 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 6.7E-19 T 11-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UP12_18350 be2623d65322275ed77b24271171eef6 97 Gene3D G3DSA:3.30.70.100 2 96 5.8E-27 T 11-10-2018 UP12_18350 be2623d65322275ed77b24271171eef6 97 SUPERFAMILY SSF54909 1 92 5.37E-27 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_01880 a4e1496fd56971fcb7bced4ebae8b2b6 261 Gene3D G3DSA:3.60.110.10 1 261 4.0E-92 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UP12_01880 a4e1496fd56971fcb7bced4ebae8b2b6 261 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 143 163 - T 11-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site UP12_01880 a4e1496fd56971fcb7bced4ebae8b2b6 261 SUPERFAMILY SSF56317 1 257 1.57E-77 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UP12_01880 a4e1496fd56971fcb7bced4ebae8b2b6 261 Pfam PF00795 Carbon-nitrogen hydrolase 2 248 3.5E-54 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 Pfam PF00158 Sigma-54 interaction domain 307 472 7.8E-65 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 Gene3D G3DSA:3.40.50.300 295 476 4.3E-60 T 11-10-2018 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 Gene3D G3DSA:1.10.10.60 551 615 7.9E-10 T 11-10-2018 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 Gene3D G3DSA:1.10.8.60 477 538 4.5E-12 T 11-10-2018 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 514 523 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 Pfam PF01590 GAF domain 99 187 5.6E-7 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 SUPERFAMILY SSF55781 87 210 7.2E-6 T 11-10-2018 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 SUPERFAMILY SSF52540 307 535 3.22E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 Gene3D G3DSA:3.30.450.40 19 204 1.9E-58 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 Pfam PF02954 Bacterial regulatory protein, Fis family 572 612 1.3E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 578 595 2.0E-5 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 595 615 2.0E-5 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 SUPERFAMILY SSF46689 568 614 3.05E-8 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_02620 0c48c7bc588589fc0454b285215b3ece 615 SMART SM00382 325 473 1.0E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 220 345 2.6E-28 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 599 722 1.0E-37 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 427 576 1.0E-18 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 190 1.6E-20 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 326 332 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Gene3D G3DSA:3.40.50.1000 321 677 0.0 T 11-10-2018 IPR023214 HAD superfamily UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 SMART SM00831 2 76 3.0E-28 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Pfam PF00122 E1-E2 ATPase 111 304 3.9E-51 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 SUPERFAMILY SSF81653 114 224 1.03E-30 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 7.3E-19 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Gene3D G3DSA:2.70.150.10 16 227 0.0 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Pfam PF00702 haloacid dehalogenase-like hydrolase 323 646 1.8E-25 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 455 473 4.7E-18 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 77 97 4.7E-18 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 317 338 4.7E-18 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 244 266 4.7E-18 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Gene3D G3DSA:3.40.1110.10 334 537 0.0 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 SUPERFAMILY SSF56784 322 736 2.27E-64 T 11-10-2018 IPR036412 HAD-like superfamily UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 SUPERFAMILY SSF81660 332 534 1.24E-58 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 53 882 2.8E-215 T 11-10-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 541 8.9E-41 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 668 8.9E-41 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 8.9E-41 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 8.9E-41 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 651 8.9E-41 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 8.9E-41 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Gene3D G3DSA:1.20.1110.10 54 877 0.0 T 11-10-2018 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 Pfam PF00689 Cation transporting ATPase, C-terminus 716 881 2.0E-51 T 11-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 UP12_07620 c7db2b1d009855315e9c9db911b77b3b 891 SUPERFAMILY SSF81665 1 881 2.75E-136 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UP12_03630 0b587ba74caefebaa3d4396c832a721e 324 Pfam PF01207 Dihydrouridine synthase (Dus) 15 315 7.6E-48 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UP12_03630 0b587ba74caefebaa3d4396c832a721e 324 Gene3D G3DSA:3.20.20.70 13 248 4.4E-61 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_03630 0b587ba74caefebaa3d4396c832a721e 324 PIRSF PIRSF006621 1 324 2.4E-83 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UP12_03630 0b587ba74caefebaa3d4396c832a721e 324 SUPERFAMILY SSF51395 13 318 1.31E-59 T 11-10-2018 UP12_03630 0b587ba74caefebaa3d4396c832a721e 324 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 11-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 UP12_16280 10bef960f71602f1b9aa36ffa4253636 391 Pfam PF13393 Histidyl-tRNA synthetase 9 317 2.2E-77 T 11-10-2018 UP12_16280 10bef960f71602f1b9aa36ffa4253636 391 SUPERFAMILY SSF55681 5 321 3.68E-63 T 11-10-2018 UP12_16280 10bef960f71602f1b9aa36ffa4253636 391 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 11 321 2.3E-99 T 11-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 UP12_16280 10bef960f71602f1b9aa36ffa4253636 391 Gene3D G3DSA:3.40.50.12590 325 390 8.4E-18 T 11-10-2018 UP12_16280 10bef960f71602f1b9aa36ffa4253636 391 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 371 35.405 T 11-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 UP12_16280 10bef960f71602f1b9aa36ffa4253636 391 Gene3D G3DSA:3.30.930.10 1 322 1.1E-102 T 11-10-2018 UP12_16280 10bef960f71602f1b9aa36ffa4253636 391 PIRSF PIRSF001549 1 388 1.1E-81 T 11-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 SUPERFAMILY SSF53748 1 393 1.65E-163 T 11-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.098 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 Pfam PF00162 Phosphoglycerate kinase 6 383 1.5E-165 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 Gene3D G3DSA:3.40.50.1260 169 383 4.3E-165 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PIRSF PIRSF000724 1 394 3.0E-160 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 Gene3D G3DSA:3.40.50.1260 7 391 4.3E-165 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 7.0E-97 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15925 0b6479192d4e6636b919bd55eb098c0b 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 11-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_01655 3d579e49b5bbe081a6a947b3e120a633 443 Pfam PF15609 Phosphoribosyl transferase 19 239 1.5E-71 T 11-10-2018 UP12_01655 3d579e49b5bbe081a6a947b3e120a633 443 Pfam PF12500 TRSP domain C terminus to PRTase_2 296 420 2.0E-43 T 11-10-2018 IPR022537 TRSP domain UP12_01655 3d579e49b5bbe081a6a947b3e120a633 443 PIRSF PIRSF020967 84 251 2.8E-24 T 11-10-2018 IPR011214 Uncharacterised conserved protein UCP020967 UP12_01655 3d579e49b5bbe081a6a947b3e120a633 443 PIRSF PIRSF020967 288 435 4.5E-11 T 11-10-2018 IPR011214 Uncharacterised conserved protein UCP020967 UP12_01655 3d579e49b5bbe081a6a947b3e120a633 443 PIRSF PIRSF020967 3 69 4.8E-12 T 11-10-2018 IPR011214 Uncharacterised conserved protein UCP020967 UP12_01655 3d579e49b5bbe081a6a947b3e120a633 443 Gene3D G3DSA:3.40.50.2020 59 248 2.6E-6 T 11-10-2018 UP12_01655 3d579e49b5bbe081a6a947b3e120a633 443 SUPERFAMILY SSF53271 80 210 2.98E-8 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_11460 70f112f1d82f0725db411b472d1374c7 295 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 2 288 8.9E-168 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 Gene3D G3DSA:3.30.930.10 1 204 3.7E-106 T 11-10-2018 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 3 280 3.7E-147 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 SUPERFAMILY SSF55681 1 280 6.21E-131 T 11-10-2018 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 Gene3D G3DSA:1.20.58.180 205 286 1.5E-36 T 11-10-2018 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 281 57.655 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 133 153 1.7E-67 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 241 257 1.7E-67 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 76 96 1.7E-67 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 107 131 1.7E-67 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 156 171 1.7E-67 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11460 70f112f1d82f0725db411b472d1374c7 295 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 55 70 1.7E-67 T 11-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 1.6E-46 T 11-10-2018 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 1.6E-46 T 11-10-2018 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 106 126 1.6E-46 T 11-10-2018 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 1.6E-46 T 11-10-2018 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 1.6E-46 T 11-10-2018 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 153 174 1.6E-46 T 11-10-2018 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 1.6E-46 T 11-10-2018 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 116 7.4E-12 T 11-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 Pfam PF13244 Domain of unknown function (DUF4040) 635 700 2.2E-21 T 11-10-2018 IPR025383 Domain of unknown function DUF4040 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 Pfam PF00361 Proton-conducting membrane transporter 129 424 3.7E-69 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 4 792 0.0 T 11-10-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 259 281 2.9E-7 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 79 99 2.9E-7 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UP12_14920 03d3bb612327ab0f5f8dbe846cdb0578 801 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 365 387 2.9E-7 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 UP12_11980 dd176ae21d7e11ee6b43fc91ef2323de 88 PIRSF PIRSF037258 1 88 1.9E-45 T 11-10-2018 IPR009309 Uncharacterised protein family UPF0297 UP12_11980 dd176ae21d7e11ee6b43fc91ef2323de 88 Hamap MF_01507 UPF0297 protein . 1 85 28.123 T 11-10-2018 IPR009309 Uncharacterised protein family UPF0297 UP12_11980 dd176ae21d7e11ee6b43fc91ef2323de 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 83 1.2E-37 T 11-10-2018 IPR009309 Uncharacterised protein family UPF0297 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 Pfam PF01416 tRNA pseudouridine synthase 7 104 1.6E-11 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 Pfam PF01416 tRNA pseudouridine synthase 144 246 3.5E-32 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 SUPERFAMILY SSF55120 1 247 5.47E-87 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 245 35.815 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 Gene3D G3DSA:3.30.70.580 1 106 7.2E-36 T 11-10-2018 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 Gene3D G3DSA:3.30.70.660 107 243 1.2E-48 T 11-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 6.7E-73 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_00890 e8d44936ec3e987d277e9df79afb0363 247 PIRSF PIRSF001430 1 247 1.0E-83 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_10595 7387116b518326d6c31812337257c32d 215 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 9 207 5.4E-75 T 11-10-2018 IPR014196 Stage II sporulation protein M UP12_10595 7387116b518326d6c31812337257c32d 215 Pfam PF01944 Stage II sporulation protein M 25 202 1.1E-25 T 11-10-2018 IPR002798 Stage II sporulation protein M-like UP12_10595 7387116b518326d6c31812337257c32d 215 PIRSF PIRSF038973 1 214 7.7E-67 T 11-10-2018 IPR014196 Stage II sporulation protein M UP12_09375 91bc35ffb7ea3cb05611eb09ab52f2fb 534 Pfam PF04616 Glycosyl hydrolases family 43 3 301 1.3E-108 T 11-10-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 UP12_09375 91bc35ffb7ea3cb05611eb09ab52f2fb 534 SUPERFAMILY SSF49899 326 532 2.89E-68 T 11-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UP12_09375 91bc35ffb7ea3cb05611eb09ab52f2fb 534 Gene3D G3DSA:2.60.120.200 328 533 9.2E-62 T 11-10-2018 UP12_09375 91bc35ffb7ea3cb05611eb09ab52f2fb 534 Gene3D G3DSA:2.115.10.20 1 326 3.2E-105 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UP12_09375 91bc35ffb7ea3cb05611eb09ab52f2fb 534 SUPERFAMILY SSF75005 3 317 2.43E-103 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily UP12_08395 3e03c69439682f05c502293b34748804 441 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 151 161 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UP12_08395 3e03c69439682f05c502293b34748804 441 Gene3D G3DSA:3.40.50.200 123 441 8.8E-99 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_08395 3e03c69439682f05c502293b34748804 441 Gene3D G3DSA:3.30.70.80 48 122 5.4E-8 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UP12_08395 3e03c69439682f05c502293b34748804 441 PRINTS PR00723 Subtilisin serine protease family (S8) signature 381 397 2.7E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_08395 3e03c69439682f05c502293b34748804 441 PRINTS PR00723 Subtilisin serine protease family (S8) signature 146 165 2.7E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_08395 3e03c69439682f05c502293b34748804 441 PRINTS PR00723 Subtilisin serine protease family (S8) signature 183 196 2.7E-18 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_08395 3e03c69439682f05c502293b34748804 441 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 382 392 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_08395 3e03c69439682f05c502293b34748804 441 Pfam PF00082 Subtilase family 146 421 1.5E-53 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_08395 3e03c69439682f05c502293b34748804 441 SUPERFAMILY SSF52743 129 440 7.07E-81 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_08395 3e03c69439682f05c502293b34748804 441 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 187 197 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 83 168 3.2E-38 T 11-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 7 169 4.5E-77 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 7 76 2.9E-32 T 11-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 SUPERFAMILY SSF54364 5 78 2.88E-29 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 170 31.017 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 Gene3D G3DSA:3.30.110.10 79 171 2.3E-37 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 SUPERFAMILY SSF55200 82 170 7.46E-33 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 Gene3D G3DSA:3.10.20.80 1 78 5.7E-34 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 UP12_12965 29e7f2ad3c5c33b5ccdbc771b9cb6191 171 ProSitePatterns PS00938 Initiation factor 3 signature. 58 71 - T 11-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 UP12_10625 51b68701f001f5e99dd496789b04c393 307 SUPERFAMILY SSF51430 2 298 1.31E-78 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_10625 51b68701f001f5e99dd496789b04c393 307 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.6E-7 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_10625 51b68701f001f5e99dd496789b04c393 307 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.6E-7 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_10625 51b68701f001f5e99dd496789b04c393 307 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.6E-7 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_10625 51b68701f001f5e99dd496789b04c393 307 Gene3D G3DSA:3.20.20.100 1 296 4.1E-105 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_10625 51b68701f001f5e99dd496789b04c393 307 Pfam PF00248 Aldo/keto reductase family 18 292 1.3E-65 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain UP12_16610 bb203437aefa7ce6cde87cd268d67a76 222 Pfam PF01205 Uncharacterized protein family UPF0029 20 124 6.5E-33 T 11-10-2018 IPR001498 Impact, N-terminal UP12_16610 bb203437aefa7ce6cde87cd268d67a76 222 Gene3D G3DSA:3.30.230.30 1 132 7.3E-52 T 11-10-2018 IPR036956 Impact, N-terminal domain superfamily UP12_16610 bb203437aefa7ce6cde87cd268d67a76 222 SUPERFAMILY SSF54980 135 199 5.61E-12 T 11-10-2018 IPR035647 EF-G domain III/V-like UP12_16610 bb203437aefa7ce6cde87cd268d67a76 222 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 9.0E-20 T 11-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal UP12_16610 bb203437aefa7ce6cde87cd268d67a76 222 SUPERFAMILY SSF54211 3 132 4.93E-44 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_16610 bb203437aefa7ce6cde87cd268d67a76 222 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 202 8.0E-83 T 11-10-2018 IPR015796 Impact family, bacterial/archaeal UP12_16610 bb203437aefa7ce6cde87cd268d67a76 222 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 11-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site UP12_16625 c979d3f2d683795e70d2c3d0f2a6d801 396 Pfam PF13692 Glycosyl transferases group 1 222 359 2.9E-13 T 11-10-2018 UP12_16625 c979d3f2d683795e70d2c3d0f2a6d801 396 Gene3D G3DSA:3.40.50.2000 26 215 3.9E-6 T 11-10-2018 UP12_16625 c979d3f2d683795e70d2c3d0f2a6d801 396 SUPERFAMILY SSF53756 39 386 1.1E-28 T 11-10-2018 UP12_16625 c979d3f2d683795e70d2c3d0f2a6d801 396 Gene3D G3DSA:3.40.50.2000 216 368 5.5E-30 T 11-10-2018 UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 1.5E-30 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 11-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.9E-20 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.9E-20 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.9E-20 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 Gene3D G3DSA:3.30.1340.10 1 85 9.9E-35 T 11-10-2018 IPR035895 HPr-like superfamily UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 Pfam PF00381 PTS HPr component phosphorylation site 2 82 1.3E-30 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like UP12_16205 7f4fe402ac945bc0ca719da597eb9fb5 85 SUPERFAMILY SSF55594 3 83 9.81E-29 T 11-10-2018 IPR035895 HPr-like superfamily UP12_09195 7c580e9d8c3e33b54ad236812c7781ee 446 Pfam PF13183 4Fe-4S dicluster domain 23 92 1.1E-12 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UP12_09195 7c580e9d8c3e33b54ad236812c7781ee 446 SUPERFAMILY SSF46548 19 106 7.32E-19 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_09195 7c580e9d8c3e33b54ad236812c7781ee 446 PIRSF PIRSF000139 6 442 3.3E-141 T 11-10-2018 UP12_09195 7c580e9d8c3e33b54ad236812c7781ee 446 Pfam PF02754 Cysteine-rich domain 327 411 2.3E-14 T 11-10-2018 IPR004017 Cysteine-rich domain UP12_09195 7c580e9d8c3e33b54ad236812c7781ee 446 Pfam PF02754 Cysteine-rich domain 196 278 1.3E-19 T 11-10-2018 IPR004017 Cysteine-rich domain UP12_09195 7c580e9d8c3e33b54ad236812c7781ee 446 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UP12_09195 7c580e9d8c3e33b54ad236812c7781ee 446 Gene3D G3DSA:1.10.1060.10 1 114 1.8E-9 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_17500 25350cc7d7bbb5f7ccf7cdbeb994ac57 73 Hamap MF_01863 UPF0741 protein . 1 73 29.391 T 11-10-2018 IPR020880 Protein of unknown function UPF0741 UP12_17500 25350cc7d7bbb5f7ccf7cdbeb994ac57 73 Pfam PF07293 Protein of unknown function (DUF1450) 8 73 2.3E-8 T 11-10-2018 IPR009910 Protein of unknown function DUF1450 UP12_02810 dd58c6fdf2e24bbd59f08fb103fcd117 401 Gene3D G3DSA:1.25.40.10 10 160 3.9E-52 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_02810 dd58c6fdf2e24bbd59f08fb103fcd117 401 SMART SM00028 229 262 0.074 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_02810 dd58c6fdf2e24bbd59f08fb103fcd117 401 SMART SM00028 148 181 45.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_02810 dd58c6fdf2e24bbd59f08fb103fcd117 401 SMART SM00028 268 301 2.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_02810 dd58c6fdf2e24bbd59f08fb103fcd117 401 Pfam PF13424 Tetratricopeptide repeat 203 261 1.2E-10 T 11-10-2018 UP12_02810 dd58c6fdf2e24bbd59f08fb103fcd117 401 Gene3D G3DSA:1.25.40.10 161 395 2.0E-68 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_02810 dd58c6fdf2e24bbd59f08fb103fcd117 401 SUPERFAMILY SSF48452 126 303 1.8E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_14070 24f31e20c71c53f1e0104bffd065e680 211 SMART SM00530 11 66 2.3E-11 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_14070 24f31e20c71c53f1e0104bffd065e680 211 SUPERFAMILY SSF47413 5 70 5.91E-14 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_14070 24f31e20c71c53f1e0104bffd065e680 211 Pfam PF06803 Protein of unknown function (DUF1232) 168 201 3.0E-13 T 11-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 UP12_14070 24f31e20c71c53f1e0104bffd065e680 211 Gene3D G3DSA:1.10.260.40 3 78 4.4E-14 T 11-10-2018 UP12_14070 24f31e20c71c53f1e0104bffd065e680 211 Pfam PF01381 Helix-turn-helix 12 66 1.7E-12 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 Pfam PF04963 Sigma-54 factor, core binding domain 73 257 1.3E-51 T 11-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 PIRSF PIRSF000774 1 432 9.7E-120 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 Gene3D G3DSA:1.10.10.60 371 429 6.8E-22 T 11-10-2018 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 PRINTS PR00045 Sigma-54 factor signature 346 357 8.4E-26 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 PRINTS PR00045 Sigma-54 factor signature 142 159 8.4E-26 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 PRINTS PR00045 Sigma-54 factor signature 330 342 8.4E-26 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 PRINTS PR00045 Sigma-54 factor signature 405 423 8.4E-26 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 Pfam PF04552 Sigma-54, DNA binding domain 272 430 2.0E-56 T 11-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 410 417 - T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 Gene3D G3DSA:1.10.10.1330 75 186 1.0E-27 T 11-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 48 1.9E-13 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 318 337 - T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_15960 7f9417c3fe71f12fae8e3814ff3045de 432 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 429 1.6E-128 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 UP12_08880 07f5d64f56d9d72e71459d724da159c2 367 SUPERFAMILY SSF53686 3 365 6.29E-87 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UP12_08880 07f5d64f56d9d72e71459d724da159c2 367 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 92 105 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UP12_08880 07f5d64f56d9d72e71459d724da159c2 367 Gene3D G3DSA:3.40.50.1100 100 196 1.0E-94 T 11-10-2018 UP12_08880 07f5d64f56d9d72e71459d724da159c2 367 Gene3D G3DSA:3.40.50.1100 51 366 1.0E-94 T 11-10-2018 UP12_08880 07f5d64f56d9d72e71459d724da159c2 367 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 69 361 3.2E-64 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UP12_05575 cf7c2601e35d34d9991288ae380c4e99 258 SUPERFAMILY SSF53633 1 253 4.19E-64 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_05575 cf7c2601e35d34d9991288ae380c4e99 258 Gene3D G3DSA:3.40.1160.10 1 240 4.3E-72 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_05575 cf7c2601e35d34d9991288ae380c4e99 258 TIGRFAM TIGR00761 argB: acetylglutamate kinase 4 232 5.5E-81 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_05575 cf7c2601e35d34d9991288ae380c4e99 258 PIRSF PIRSF000728 1 254 9.8E-86 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_05575 cf7c2601e35d34d9991288ae380c4e99 258 Hamap MF_00082 Acetylglutamate kinase [argB]. 2 244 40.793 T 11-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 UP12_05575 cf7c2601e35d34d9991288ae380c4e99 258 Pfam PF00696 Amino acid kinase family 3 234 2.8E-40 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UP12_00775 b79a30ca377c00a9fe7434fdcb369055 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.6E-54 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UP12_00775 b79a30ca377c00a9fe7434fdcb369055 122 SMART SM01374 1 122 5.1E-85 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UP12_00775 b79a30ca377c00a9fe7434fdcb369055 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 11-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00775 b79a30ca377c00a9fe7434fdcb369055 122 SUPERFAMILY SSF50193 1 122 5.76E-50 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00775 b79a30ca377c00a9fe7434fdcb369055 122 Gene3D G3DSA:2.40.150.20 1 122 4.9E-53 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00775 b79a30ca377c00a9fe7434fdcb369055 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.298 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 UP12_00775 b79a30ca377c00a9fe7434fdcb369055 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 8.4E-58 T 11-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 UP12_11785 5003e2ee6021712bf682f33fbec6f6fa 118 Gene3D G3DSA:1.10.10.10 4 114 2.0E-40 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11785 5003e2ee6021712bf682f33fbec6f6fa 118 SUPERFAMILY SSF46785 6 112 7.49E-36 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_11785 5003e2ee6021712bf682f33fbec6f6fa 118 Pfam PF01638 HxlR-like helix-turn-helix 22 111 3.3E-40 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_16800 fda65788dfce710062a5969afba800b9 336 Gene3D G3DSA:3.40.50.2300 71 318 5.9E-71 T 11-10-2018 UP12_16800 fda65788dfce710062a5969afba800b9 336 SUPERFAMILY SSF53822 66 325 3.0E-59 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_16800 fda65788dfce710062a5969afba800b9 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 56 3.8E-16 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_16800 fda65788dfce710062a5969afba800b9 336 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 11-10-2018 UP12_16800 fda65788dfce710062a5969afba800b9 336 Gene3D G3DSA:3.40.50.2300 166 297 5.9E-71 T 11-10-2018 UP12_16800 fda65788dfce710062a5969afba800b9 336 SUPERFAMILY SSF47413 8 67 1.48E-14 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_16800 fda65788dfce710062a5969afba800b9 336 Pfam PF13377 Periplasmic binding protein-like domain 177 335 6.8E-27 T 11-10-2018 UP12_16800 fda65788dfce710062a5969afba800b9 336 SMART SM00354 8 79 7.6E-31 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_16800 fda65788dfce710062a5969afba800b9 336 Gene3D G3DSA:1.10.260.40 7 66 7.2E-19 T 11-10-2018 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 74 86 3.1E-18 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 3.1E-18 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 132 151 3.1E-18 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 ProSitePatterns PS00761 Signal peptidases I signature 3. 137 150 - T 11-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 ProSitePatterns PS00760 Signal peptidases I lysine active site. 76 88 - T 11-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 SUPERFAMILY SSF51306 24 164 1.73E-40 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 Gene3D G3DSA:2.10.109.10 54 168 3.1E-35 T 11-10-2018 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 9 163 7.1E-40 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 11-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 UP12_05285 35c76ae3f9fa3407498a7cff8d63f930 170 Pfam PF00717 Peptidase S24-like 30 97 6.9E-16 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 81 100 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 325 343 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 151 171 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 208 229 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 105 121 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 122 139 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 16 34 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 PRINTS PR00681 Ribosomal protein S1 signature 286 305 5.8E-51 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SUPERFAMILY SSF50249 10 109 6.86E-18 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SUPERFAMILY SSF50249 88 170 1.42E-15 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Gene3D G3DSA:2.40.50.140 2 94 9.0E-16 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SUPERFAMILY SSF50249 185 273 2.68E-28 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SMART SM00316 100 167 1.9E-8 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SMART SM00316 14 84 9.1E-14 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SMART SM00316 186 256 1.4E-28 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SMART SM00316 271 342 2.1E-26 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Gene3D G3DSA:2.40.50.140 95 180 6.0E-12 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Pfam PF00575 S1 RNA binding domain 184 256 2.1E-26 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Pfam PF00575 S1 RNA binding domain 98 167 2.3E-15 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Pfam PF00575 S1 RNA binding domain 13 83 7.9E-15 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Pfam PF00575 S1 RNA binding domain 269 342 2.0E-24 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Gene3D G3DSA:2.40.50.140 182 265 3.6E-30 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 Gene3D G3DSA:2.40.50.140 267 352 3.3E-29 T 11-10-2018 UP12_10285 310e15b2d1726cf8220c7874b5d58cb2 383 SUPERFAMILY SSF50249 254 356 3.23E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_04205 974ee5369c42c03b40fe7b854b99b239 308 SUPERFAMILY SSF53807 36 298 6.67E-51 T 11-10-2018 UP12_04205 974ee5369c42c03b40fe7b854b99b239 308 Pfam PF01497 Periplasmic binding protein 95 280 3.1E-26 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_04205 974ee5369c42c03b40fe7b854b99b239 308 Gene3D G3DSA:3.40.50.1980 32 146 3.8E-24 T 11-10-2018 UP12_04205 974ee5369c42c03b40fe7b854b99b239 308 Gene3D G3DSA:3.40.50.1980 147 306 6.3E-51 T 11-10-2018 UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 291 5.2E-121 T 11-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 SUPERFAMILY SSF52151 4 311 1.07E-80 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 PIRSF PIRSF000446 1 311 3.0E-128 T 11-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 314 1.0E-48 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 Gene3D G3DSA:3.30.70.250 124 197 5.2E-100 T 11-10-2018 UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 Pfam PF00698 Acyl transferase domain 6 288 8.9E-42 T 11-10-2018 IPR014043 Acyl transferase UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 SUPERFAMILY SSF55048 128 192 4.97E-15 T 11-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UP12_07745 4e237943f4aacd183962d2cde78b0c49 314 Gene3D G3DSA:3.40.366.10 6 286 5.2E-100 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UP12_05030 7ad41430d6abad29723720f803ce76f5 256 Gene3D G3DSA:1.10.12.10 199 255 1.2E-17 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal UP12_05030 7ad41430d6abad29723720f803ce76f5 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 254 2.1E-42 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UP12_05030 7ad41430d6abad29723720f803ce76f5 256 Gene3D G3DSA:3.90.226.10 1 193 1.0E-50 T 11-10-2018 UP12_05030 7ad41430d6abad29723720f803ce76f5 256 SUPERFAMILY SSF52096 3 254 6.14E-64 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_03920 70bbe1a33d5e936060d55cf894b9a341 252 Pfam PF05675 Protein of unknown function (DUF817) 4 237 2.6E-100 T 11-10-2018 IPR008535 Protein of unknown function DUF817 UP12_03920 70bbe1a33d5e936060d55cf894b9a341 252 PIRSF PIRSF009141 1 251 8.8E-110 T 11-10-2018 IPR008535 Protein of unknown function DUF817 UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 425 526 6.2E-16 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 SUPERFAMILY SSF55874 398 525 7.07E-24 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 Gene3D G3DSA:3.30.450.20 34 168 8.9E-18 T 11-10-2018 UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 Pfam PF17203 Single cache domain 3 40 172 3.4E-10 T 11-10-2018 IPR033463 Single cache domain 3 UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 325 366 8.6E-8 T 11-10-2018 IPR039506 SpoOB, alpha-helical domain UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 SUPERFAMILY SSF103190 38 169 6.67E-21 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 488 506 1.1E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 1.1E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 512 525 1.1E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 Gene3D G3DSA:3.30.565.10 375 525 3.9E-26 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 SMART SM00387 420 528 3.5E-19 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 Gene3D G3DSA:3.30.450.20 203 315 2.1E-17 T 11-10-2018 UP12_03860 42e9e8da04b52c988999cc9be58056f7 531 SUPERFAMILY SSF55890 326 392 7.59E-10 T 11-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 UP12_00875 9540642b39d74f187d56f8b25ee80d9a 280 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_00875 9540642b39d74f187d56f8b25ee80d9a 280 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 6 274 3.4E-119 T 11-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 UP12_00875 9540642b39d74f187d56f8b25ee80d9a 280 Gene3D G3DSA:3.40.50.300 2 279 1.6E-79 T 11-10-2018 UP12_00875 9540642b39d74f187d56f8b25ee80d9a 280 SMART SM00382 33 218 2.9E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00875 9540642b39d74f187d56f8b25ee80d9a 280 SUPERFAMILY SSF52540 5 230 2.6E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00875 9540642b39d74f187d56f8b25ee80d9a 280 Pfam PF00005 ABC transporter 24 170 1.9E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04010 1f17d5aef6132f838680fb667e4f1a7d 393 Gene3D G3DSA:1.20.1250.20 2 183 2.4E-21 T 11-10-2018 UP12_04010 1f17d5aef6132f838680fb667e4f1a7d 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 258 275 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_04010 1f17d5aef6132f838680fb667e4f1a7d 393 Gene3D G3DSA:1.20.1250.20 199 385 1.3E-23 T 11-10-2018 UP12_04010 1f17d5aef6132f838680fb667e4f1a7d 393 SUPERFAMILY SSF103473 5 375 1.15E-48 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_04010 1f17d5aef6132f838680fb667e4f1a7d 393 Pfam PF07690 Major Facilitator Superfamily 209 386 9.0E-25 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_11305 7fcc02ebe1cb82e61715fc9c257e933d 308 Gene3D G3DSA:1.10.3720.10 81 307 3.1E-38 T 11-10-2018 IPR035906 MetI-like superfamily UP12_11305 7fcc02ebe1cb82e61715fc9c257e933d 308 SUPERFAMILY SSF161098 29 302 9.42E-39 T 11-10-2018 IPR035906 MetI-like superfamily UP12_11305 7fcc02ebe1cb82e61715fc9c257e933d 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 307 4.1E-31 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_11305 7fcc02ebe1cb82e61715fc9c257e933d 308 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 29 306 1.7E-87 T 11-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 SUPERFAMILY SSF46689 4 78 3.11E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 SUPERFAMILY SSF48498 77 189 5.53E-12 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 4.1E-16 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 Gene3D G3DSA:1.10.357.10 51 190 1.9E-17 T 11-10-2018 UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 Gene3D G3DSA:1.10.10.60 1 50 1.4E-16 T 11-10-2018 UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.2E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_05165 f771920f0f08eba072bee7d4e3694ce3 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.2E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_03180 9633d9cec3f7c11fc74cc647a031ac9a 244 Pfam PF02517 CAAX protease self-immunity 129 214 3.2E-16 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UP12_11790 eddaa66436830e9252e7bbd81f7d085e 289 Gene3D G3DSA:3.40.50.1820 27 269 2.4E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_11790 eddaa66436830e9252e7bbd81f7d085e 289 SUPERFAMILY SSF53474 32 244 1.17E-41 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_11790 eddaa66436830e9252e7bbd81f7d085e 289 Pfam PF07859 alpha/beta hydrolase fold 69 162 4.3E-20 T 11-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 Pfam PF00874 PRD domain 81 170 9.8E-23 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 Pfam PF00874 PRD domain 188 278 5.7E-18 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 Gene3D G3DSA:1.20.58.1950 229 281 1.7E-23 T 11-10-2018 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 SUPERFAMILY SSF63520 60 173 1.83E-28 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 SMART SM01061 6 64 9.4E-25 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 Gene3D G3DSA:1.10.1790.10 72 172 1.2E-31 T 11-10-2018 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 Gene3D G3DSA:2.30.24.10 1 71 4.8E-25 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 SUPERFAMILY SSF63520 182 279 1.7E-22 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 SUPERFAMILY SSF50151 7 58 4.32E-15 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 Gene3D G3DSA:1.20.890.100 173 227 1.4E-21 T 11-10-2018 UP12_06695 791d6b1701a23c2dc5c3c2cbd52ca547 284 Pfam PF03123 CAT RNA binding domain 7 61 1.7E-21 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_16820 09d8ac970cd13e50a8278ac9cc002f68 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 5 362 2.0E-67 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_16820 09d8ac970cd13e50a8278ac9cc002f68 366 Pfam PF03845 Spore germination protein 6 330 4.6E-81 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_09910 0159bc891c9e7d5363b0156bb1eb85d4 284 Gene3D G3DSA:3.20.20.370 47 283 1.2E-56 T 11-10-2018 UP12_09910 0159bc891c9e7d5363b0156bb1eb85d4 284 SUPERFAMILY SSF88713 83 280 8.16E-51 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_09910 0159bc891c9e7d5363b0156bb1eb85d4 284 Pfam PF01522 Polysaccharide deacetylase 83 193 1.2E-28 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_04780 87cf29c81597e96f14dcfdc8d5bc706c 446 Gene3D G3DSA:3.90.1150.10 15 442 1.1E-151 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_04780 87cf29c81597e96f14dcfdc8d5bc706c 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 247 284 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_04780 87cf29c81597e96f14dcfdc8d5bc706c 446 Pfam PF00202 Aminotransferase class-III 28 441 5.2E-110 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_04780 87cf29c81597e96f14dcfdc8d5bc706c 446 PIRSF PIRSF000521 16 446 2.9E-33 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_04780 87cf29c81597e96f14dcfdc8d5bc706c 446 Gene3D G3DSA:3.40.640.10 66 336 1.1E-151 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_04780 87cf29c81597e96f14dcfdc8d5bc706c 446 SUPERFAMILY SSF53383 31 444 1.78E-122 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_17930 5934d6e1000fe5457d09badb58ce972b 214 SUPERFAMILY SSF161098 9 197 7.59E-48 T 11-10-2018 IPR035906 MetI-like superfamily UP12_17930 5934d6e1000fe5457d09badb58ce972b 214 Gene3D G3DSA:1.10.3720.10 1 213 1.3E-55 T 11-10-2018 IPR035906 MetI-like superfamily UP12_17930 5934d6e1000fe5457d09badb58ce972b 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 106 2.9E-28 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_17930 5934d6e1000fe5457d09badb58ce972b 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 211 2.0E-18 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_05550 14dd5bee70156917e6bd54cd8f0af22e 102 SUPERFAMILY SSF117916 1 100 2.35E-33 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UP12_05550 14dd5bee70156917e6bd54cd8f0af22e 102 Pfam PF01883 Iron-sulfur cluster assembly protein 6 80 3.7E-23 T 11-10-2018 IPR002744 MIP18 family-like UP12_05550 14dd5bee70156917e6bd54cd8f0af22e 102 Gene3D G3DSA:3.30.300.130 1 102 5.2E-38 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily UP12_14095 727c2c75b8210f6ff6337e2b82456ff5 159 Pfam PF12867 DinB superfamily 4 152 3.5E-19 T 11-10-2018 IPR024775 DinB-like domain UP12_14095 727c2c75b8210f6ff6337e2b82456ff5 159 SUPERFAMILY SSF109854 2 159 1.36E-28 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UP12_14095 727c2c75b8210f6ff6337e2b82456ff5 159 Gene3D G3DSA:1.20.120.450 1 158 6.4E-37 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 Gene3D G3DSA:1.20.1740.10 57 448 6.9E-8 T 11-10-2018 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 Pfam PF01235 Sodium:alanine symporter family 53 444 2.4E-152 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 432 1.7E-159 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 PRINTS PR00175 Sodium/alanine symporter signature 344 366 1.4E-57 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 PRINTS PR00175 Sodium/alanine symporter signature 210 229 1.4E-57 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 PRINTS PR00175 Sodium/alanine symporter signature 91 113 1.4E-57 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 PRINTS PR00175 Sodium/alanine symporter signature 301 319 1.4E-57 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 PRINTS PR00175 Sodium/alanine symporter signature 403 423 1.4E-57 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_03990 118ffe9bfba324b5ea1b0791020833ce 451 PRINTS PR00175 Sodium/alanine symporter signature 182 200 1.4E-57 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_09750 a2d5170134d518ed37078df94d9afad2 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 8.8E-100 T 11-10-2018 IPR003797 DegV UP12_09750 a2d5170134d518ed37078df94d9afad2 280 SUPERFAMILY SSF82549 4 280 4.19E-90 T 11-10-2018 UP12_09750 a2d5170134d518ed37078df94d9afad2 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 4 279 2.4E-88 T 11-10-2018 IPR003797 DegV UP12_09750 a2d5170134d518ed37078df94d9afad2 280 Gene3D G3DSA:3.40.50.10170 1 152 6.7E-54 T 11-10-2018 UP12_09750 a2d5170134d518ed37078df94d9afad2 280 Gene3D G3DSA:3.30.1180.10 153 279 3.4E-36 T 11-10-2018 UP12_19025 0d3ee610f4e481703c48e551bb765647 149 SUPERFAMILY SSF55653 57 147 3.01E-29 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily UP12_19025 0d3ee610f4e481703c48e551bb765647 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 5.5E-31 T 11-10-2018 IPR020069 Ribosomal protein L9, C-terminal UP12_19025 0d3ee610f4e481703c48e551bb765647 149 Gene3D G3DSA:3.40.5.10 1 52 2.1E-25 T 11-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19025 0d3ee610f4e481703c48e551bb765647 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19025 0d3ee610f4e481703c48e551bb765647 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.863 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_19025 0d3ee610f4e481703c48e551bb765647 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.1E-52 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_19025 0d3ee610f4e481703c48e551bb765647 149 Gene3D G3DSA:3.10.430.100 60 149 1.7E-33 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily UP12_19025 0d3ee610f4e481703c48e551bb765647 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 6.4E-23 T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_19025 0d3ee610f4e481703c48e551bb765647 149 SUPERFAMILY SSF55658 1 56 3.14E-17 T 11-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 Hamap MF_00455 Xylose isomerase [xylA]. 18 442 54.849 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 SUPERFAMILY SSF51658 13 443 5.11E-173 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 Gene3D G3DSA:3.20.20.150 12 445 1.1E-186 T 11-10-2018 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 186 207 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 162 181 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 277 304 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 306 317 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 339 350 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 139 159 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 98 120 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 213 232 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 PRINTS PR00688 Xylose isomerase signature 235 259 1.3E-96 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 13 442 1.7E-217 T 11-10-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 UP12_09365 280960f7edfa3c6a3082eef560d00e37 445 Pfam PF01261 Xylose isomerase-like TIM barrel 127 292 2.9E-9 T 11-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UP12_07980 b7df64449e2153866ac3bc2722656505 259 Pfam PF01311 Bacterial export proteins, family 1 8 243 9.2E-72 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 UP12_07980 b7df64449e2153866ac3bc2722656505 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 16 37 2.4E-29 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 UP12_07980 b7df64449e2153866ac3bc2722656505 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 74 93 2.4E-29 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 UP12_07980 b7df64449e2153866ac3bc2722656505 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 199 218 2.4E-29 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 UP12_07980 b7df64449e2153866ac3bc2722656505 259 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 177 199 2.4E-29 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 UP12_07980 b7df64449e2153866ac3bc2722656505 259 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 9 252 1.0E-66 T 11-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 4.0E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.0E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.0E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 4.0E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 4.0E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 5.5E-34 T 11-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 195 9.1E-42 T 11-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 SUPERFAMILY SSF54719 89 200 4.58E-48 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 Gene3D G3DSA:2.40.500.20 91 202 4.8E-51 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 11-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 Gene3D G3DSA:1.10.287.990 20 90 1.2E-31 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 PIRSF PIRSF000349 1 202 2.5E-85 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_11325 8e108bc4485a31e5424c284ad61fd1f7 202 SUPERFAMILY SSF46609 1 91 7.86E-39 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 UP12_02785 d76e4291cd2d3f510d7ccb30fdc3fd49 818 PIRSF PIRSF015040 1 818 2.2E-258 T 11-10-2018 IPR016628 ATPase, SAG2001, predicted UP12_02785 d76e4291cd2d3f510d7ccb30fdc3fd49 818 SUPERFAMILY SSF52540 444 785 1.19E-22 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02785 d76e4291cd2d3f510d7ccb30fdc3fd49 818 Pfam PF12846 AAA-like domain 430 802 2.2E-121 T 11-10-2018 UP12_12510 b2c8e5028dad7f1436f4b6f75d424296 174 Gene3D G3DSA:3.60.21.10 1 169 7.8E-46 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_12510 b2c8e5028dad7f1436f4b6f75d424296 174 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 145 4.6E-31 T 11-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 UP12_12510 b2c8e5028dad7f1436f4b6f75d424296 174 SUPERFAMILY SSF56300 1 158 3.11E-42 T 11-10-2018 UP12_12510 b2c8e5028dad7f1436f4b6f75d424296 174 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 149 1.7E-36 T 11-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 SUPERFAMILY SSF48150 1 211 8.48E-74 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 170 2.2E-24 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 Gene3D G3DSA:1.10.1670.10 17 205 3.1E-82 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 1.3E-4 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 SMART SM00525 188 208 8.5E-4 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 Pfam PF00633 Helix-hairpin-helix motif 100 128 9.8E-10 T 11-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 PIRSF PIRSF001435 2 214 1.3E-58 T 11-10-2018 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 TIGRFAM TIGR01083 nth: endonuclease III 4 196 2.6E-89 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 SMART SM00478 39 187 4.2E-71 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 11-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 Gene3D G3DSA:1.10.340.30 22 133 3.1E-82 T 11-10-2018 UP12_10020 4dddf7e65c496f5c9221fd7b3b0e11b9 220 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.659 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 PIRSF PIRSF000077 1 104 9.5E-43 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 Gene3D G3DSA:3.40.30.10 1 104 3.1E-36 T 11-10-2018 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 SUPERFAMILY SSF52833 3 104 5.68E-37 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_12845 45828455349abee09b1fb42b8dbee02e 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 2.2E-39 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 Pfam PF00085 Thioredoxin 3 103 1.4E-30 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 PRINTS PR00421 Thioredoxin family signature 20 28 1.3E-8 T 11-10-2018 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.3E-8 T 11-10-2018 UP12_12845 45828455349abee09b1fb42b8dbee02e 104 PRINTS PR00421 Thioredoxin family signature 28 37 1.3E-8 T 11-10-2018 UP12_02825 36bcda82283dca1c45b06acbc9166869 111 Gene3D G3DSA:1.10.10.10 1 111 1.5E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02825 36bcda82283dca1c45b06acbc9166869 111 SUPERFAMILY SSF46785 8 107 4.12E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02825 36bcda82283dca1c45b06acbc9166869 111 Pfam PF01638 HxlR-like helix-turn-helix 19 109 5.0E-25 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 SUPERFAMILY SSF52540 988 1172 5.73E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 SUPERFAMILY SSF52540 639 894 1.38E-30 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 Pfam PF12538 DNA transporter 3 113 3.8E-33 T 11-10-2018 IPR022206 Firmicutes EssC, N-terminal UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 SUPERFAMILY SSF52540 1260 1419 9.32E-9 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 Gene3D G3DSA:3.40.50.300 956 1243 1.1E-63 T 11-10-2018 UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 TIGRFAM TIGR03928 T7_EssCb_Firm: type VII secretion protein EssC 206 1481 0.0 T 11-10-2018 IPR023839 Firmicutes EssC, C-terminal UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 Gene3D G3DSA:3.40.50.300 617 950 5.0E-78 T 11-10-2018 UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 Gene3D G3DSA:3.40.50.300 1250 1483 1.0E-23 T 11-10-2018 UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 Pfam PF01580 FtsK/SpoIIIE family 1257 1334 5.7E-6 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 Pfam PF01580 FtsK/SpoIIIE family 646 853 1.8E-30 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UP12_15055 7262e4000c4774b6e5a0f1a13a1df0a0 1491 Pfam PF01580 FtsK/SpoIIIE family 986 1159 2.8E-23 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 Pfam PF01979 Amidohydrolase family 66 349 4.8E-37 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 Hamap MF_01518 Adenine deaminase [ade]. 20 573 38.722 T 11-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 TIGRFAM TIGR01178 ade: adenine deaminase 21 572 9.5E-222 T 11-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 SUPERFAMILY SSF51338 11 356 2.09E-18 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 SUPERFAMILY SSF51556 70 318 7.08E-45 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 Gene3D G3DSA:3.20.20.140 70 313 9.9E-125 T 11-10-2018 UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 Pfam PF13382 Adenine deaminase C-terminal domain 402 570 4.2E-61 T 11-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 UP12_07025 e6f209d54518fc4abd32b1cb99439ab4 576 Gene3D G3DSA:2.30.40.10 12 350 9.9E-125 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 SUPERFAMILY SSF55874 8 220 1.14E-73 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 SUPERFAMILY SSF56719 398 630 1.26E-93 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 SMART SM00387 33 177 5.6E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Pfam PF01751 Toprim domain 423 534 5.4E-19 T 11-10-2018 IPR006171 TOPRIM domain UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 SUPERFAMILY SSF54211 225 395 8.91E-65 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Gene3D G3DSA:3.40.50.670 403 638 1.6E-112 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 11-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 568 627 6.5E-30 T 11-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 638 0.0 T 11-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 638 98.491 T 11-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 176 4.6E-22 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Pfam PF00204 DNA gyrase B 225 394 2.8E-66 T 11-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Gene3D G3DSA:3.30.565.10 4 223 9.2E-94 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 SMART SM00433 37 631 0.0 T 11-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 115 129 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 490 506 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 72 85 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 528 540 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 508 525 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 37 52 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 424 438 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 272 285 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR00418 DNA topoisomerase II family signature 570 586 4.6E-74 T 11-10-2018 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 Gene3D G3DSA:3.30.230.10 224 402 7.6E-76 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 316 332 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 607 623 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 8 18 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 474 483 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 364 378 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 224 246 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 378 398 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_00030 9f1fcef722545ae369e6eb375ba4b76b 638 PRINTS PR01159 DNA gyrase subunit B signature 591 603 1.0E-78 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 UP12_02665 97445f40535393bce9203693b537e2f6 170 Gene3D G3DSA:3.40.390.50 5 111 2.1E-7 T 11-10-2018 UP12_02665 97445f40535393bce9203693b537e2f6 170 SUPERFAMILY SSF55486 61 125 6.72E-5 T 11-10-2018 UP12_02665 97445f40535393bce9203693b537e2f6 170 Pfam PF06114 IrrE N-terminal-like domain 27 146 3.8E-19 T 11-10-2018 IPR010359 IrrE N-terminal-like domain UP12_08715 85669c9db85bb9e4cc5caf4c537474ea 55 SUPERFAMILY SSF140500 4 53 2.49E-15 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 UP12_08715 85669c9db85bb9e4cc5caf4c537474ea 55 Gene3D G3DSA:1.20.58.990 3 54 3.8E-11 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 UP12_08715 85669c9db85bb9e4cc5caf4c537474ea 55 Pfam PF09388 Spo0E like sporulation regulatory protein 6 47 1.9E-15 T 11-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 UP12_10185 f1367f3666c3a9c6fabfc45390305ac8 127 PIRSF PIRSF005965 1 125 1.1E-49 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_10185 f1367f3666c3a9c6fabfc45390305ac8 127 SUPERFAMILY SSF55298 1 125 8.63E-47 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_10185 f1367f3666c3a9c6fabfc45390305ac8 127 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 9 127 9.0E-44 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_10185 f1367f3666c3a9c6fabfc45390305ac8 127 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 4 119 1.0E-44 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_10185 f1367f3666c3a9c6fabfc45390305ac8 127 Pfam PF07736 Chorismate mutase type I 4 119 2.9E-46 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 UP12_10185 f1367f3666c3a9c6fabfc45390305ac8 127 Gene3D G3DSA:3.30.1330.40 1 127 4.3E-51 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 11-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 Gene3D G3DSA:3.30.572.10 1 264 1.3E-133 T 11-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 5.6E-97 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 8.1E-43 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 41.284 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.7E-50 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 2.7E-50 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 2.7E-50 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 2.7E-50 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 2.7E-50 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 Pfam PF00303 Thymidylate synthase 2 264 2.4E-129 T 11-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_09785 fa08f92b953ffec0110fadd77c657a51 264 SUPERFAMILY SSF55831 1 264 6.28E-131 T 11-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 UP12_08610 d7511f8093db4129445a0965950af2f5 238 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 62.407 T 11-10-2018 IPR022822 Lactate utilization protein A GO:0006089 UP12_08610 d7511f8093db4129445a0965950af2f5 238 Pfam PF02754 Cysteine-rich domain 132 215 1.2E-16 T 11-10-2018 IPR004017 Cysteine-rich domain UP12_08610 d7511f8093db4129445a0965950af2f5 238 Pfam PF02754 Cysteine-rich domain 3 83 6.1E-19 T 11-10-2018 IPR004017 Cysteine-rich domain UP12_13825 90284df018d4647c024125d49785b170 145 Gene3D G3DSA:1.20.1260.10 1 145 1.5E-54 T 11-10-2018 IPR012347 Ferritin-like UP12_13825 90284df018d4647c024125d49785b170 145 SUPERFAMILY SSF47240 3 145 6.81E-47 T 11-10-2018 IPR009078 Ferritin-like superfamily UP12_13825 90284df018d4647c024125d49785b170 145 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 11-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 UP12_13825 90284df018d4647c024125d49785b170 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 1.2E-14 T 11-10-2018 IPR002177 DNA-binding protein Dps UP12_13825 90284df018d4647c024125d49785b170 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 1.2E-14 T 11-10-2018 IPR002177 DNA-binding protein Dps UP12_13825 90284df018d4647c024125d49785b170 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 1.2E-14 T 11-10-2018 IPR002177 DNA-binding protein Dps UP12_13825 90284df018d4647c024125d49785b170 145 Pfam PF00210 Ferritin-like domain 10 144 5.6E-33 T 11-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 UP12_13825 90284df018d4647c024125d49785b170 145 PIRSF PIRSF005900 1 145 1.9E-47 T 11-10-2018 IPR002177 DNA-binding protein Dps UP12_13825 90284df018d4647c024125d49785b170 145 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 11-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 UP12_17995 8d9a087ae1e5ecbc0a6d6e8bfe844b20 449 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 12 435 1.2E-200 T 11-10-2018 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 UP12_17995 8d9a087ae1e5ecbc0a6d6e8bfe844b20 449 PIRSF PIRSF006351 1 443 1.2E-157 T 11-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 UP12_17995 8d9a087ae1e5ecbc0a6d6e8bfe844b20 449 TIGRFAM TIGR00359 cello_pts_IIC: PTS system, cellobiose-specific IIC component 12 435 1.2E-200 T 11-10-2018 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 UP12_17995 8d9a087ae1e5ecbc0a6d6e8bfe844b20 449 Pfam PF02378 Phosphotransferase system, EIIC 29 359 4.9E-74 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_02330 3dc3826d0651a919bfff790e45efdafb 98 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 91 1.4E-26 T 11-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane UP12_02330 3dc3826d0651a919bfff790e45efdafb 98 Pfam PF12823 Domain of unknown function (DUF3817) 6 92 1.2E-20 T 11-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane UP12_05750 cc4e8cd050aac703f06df01987c49865 686 Gene3D G3DSA:1.20.140.70 108 263 2.9E-53 T 11-10-2018 UP12_05750 cc4e8cd050aac703f06df01987c49865 686 Gene3D G3DSA:1.10.287.830 265 311 2.5E-20 T 11-10-2018 UP12_05750 cc4e8cd050aac703f06df01987c49865 686 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 91 680 1.3E-222 T 11-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 UP12_05750 cc4e8cd050aac703f06df01987c49865 686 Gene3D G3DSA:1.10.1370.20 312 685 4.3E-145 T 11-10-2018 UP12_05750 cc4e8cd050aac703f06df01987c49865 686 Pfam PF01432 Peptidase family M3 289 668 6.6E-84 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 UP12_05750 cc4e8cd050aac703f06df01987c49865 686 SUPERFAMILY SSF55486 85 664 2.66E-141 T 11-10-2018 UP12_05750 cc4e8cd050aac703f06df01987c49865 686 Pfam PF08439 Oligopeptidase F 198 267 3.7E-23 T 11-10-2018 IPR013647 Oligopeptidase F, N-terminal domain UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 SMART SM00387 419 527 1.5E-19 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 SUPERFAMILY SSF103190 37 167 3.3E-39 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 Gene3D G3DSA:3.30.450.20 199 312 2.1E-18 T 11-10-2018 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 SUPERFAMILY SSF55874 387 524 4.45E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 Gene3D G3DSA:3.30.565.10 380 532 1.5E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 511 524 1.6E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 472 1.6E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 1.6E-9 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 SUPERFAMILY SSF55890 323 413 2.62E-15 T 11-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 Gene3D G3DSA:1.10.287.130 313 379 8.9E-7 T 11-10-2018 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 322 373 4.9E-12 T 11-10-2018 IPR039506 SpoOB, alpha-helical domain UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 Pfam PF17203 Single cache domain 3 36 166 4.2E-27 T 11-10-2018 IPR033463 Single cache domain 3 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 Gene3D G3DSA:3.30.450.20 32 170 3.9E-43 T 11-10-2018 UP12_14880 01b69b185bdabf6893cb1c5f9850ca60 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 526 2.1E-18 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_02670 180b8a5972a3a8d9225587a45bf35a6c 126 SMART SM00530 6 61 4.3E-16 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_02670 180b8a5972a3a8d9225587a45bf35a6c 126 SUPERFAMILY SSF47413 1 68 5.36E-19 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_02670 180b8a5972a3a8d9225587a45bf35a6c 126 Pfam PF01381 Helix-turn-helix 7 61 2.2E-17 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_02670 180b8a5972a3a8d9225587a45bf35a6c 126 Gene3D G3DSA:1.10.260.40 3 125 1.1E-22 T 11-10-2018 UP12_04015 ba86fe2f787c7bd239911297e6592957 125 Pfam PF02566 OsmC-like protein 26 120 7.5E-18 T 11-10-2018 IPR003718 OsmC/Ohr family UP12_04015 ba86fe2f787c7bd239911297e6592957 125 Gene3D G3DSA:3.30.300.20 1 123 1.3E-19 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_04015 ba86fe2f787c7bd239911297e6592957 125 SUPERFAMILY SSF82784 4 121 1.31E-20 T 11-10-2018 IPR036102 OsmC/Ohr superfamily UP12_11505 a6f9302b7d3b55407f269ba08f315c53 93 Pfam PF07873 YabP family 27 90 9.4E-19 T 11-10-2018 IPR022476 Sporulation protein YabP/YqfC UP12_11505 a6f9302b7d3b55407f269ba08f315c53 93 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 8 91 4.2E-37 T 11-10-2018 IPR022477 Sporulation protein YqfC UP12_00460 8da885ad82dce0547d2f1cba9e09162d 285 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 27 276 5.8E-102 T 11-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 UP12_00460 8da885ad82dce0547d2f1cba9e09162d 285 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 27 42 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_00460 8da885ad82dce0547d2f1cba9e09162d 285 SUPERFAMILY SSF51717 16 278 1.18E-99 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_00460 8da885ad82dce0547d2f1cba9e09162d 285 Pfam PF00809 Pterin binding enzyme 28 261 1.1E-87 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_00460 8da885ad82dce0547d2f1cba9e09162d 285 Gene3D G3DSA:3.20.20.20 8 282 1.9E-113 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_00460 8da885ad82dce0547d2f1cba9e09162d 285 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 61 74 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 UP12_11900 ba4c91a9e98bf59cf8be9609c8bf2cfb 213 SUPERFAMILY SSF53335 8 205 1.4E-28 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_11900 ba4c91a9e98bf59cf8be9609c8bf2cfb 213 Pfam PF13489 Methyltransferase domain 36 194 9.8E-12 T 11-10-2018 UP12_11900 ba4c91a9e98bf59cf8be9609c8bf2cfb 213 Gene3D G3DSA:3.40.50.150 24 213 7.2E-43 T 11-10-2018 UP12_11900 ba4c91a9e98bf59cf8be9609c8bf2cfb 213 Hamap MF_02100 Uncharacterized methyltransferase . 2 212 46.092 T 11-10-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 UP12_12570 5dd5d46d72ca2992ae77b53e9c7e5a0e 59 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 8 45 9.8E-12 T 11-10-2018 IPR010022 Protein of unknown function XkdX UP12_12570 5dd5d46d72ca2992ae77b53e9c7e5a0e 59 TIGRFAM TIGR01669 phage_XkdX: phage uncharacterized protein, XkdX family 1 43 1.3E-9 T 11-10-2018 IPR010022 Protein of unknown function XkdX UP12_02820 afdfc132b771048094762b75f64dc315 324 SUPERFAMILY SSF51735 125 295 2.27E-36 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02820 afdfc132b771048094762b75f64dc315 324 Gene3D G3DSA:3.90.180.10 26 318 1.6E-82 T 11-10-2018 UP12_02820 afdfc132b771048094762b75f64dc315 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 93 2.6E-7 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_02820 afdfc132b771048094762b75f64dc315 324 Pfam PF13602 Zinc-binding dehydrogenase 195 318 1.9E-24 T 11-10-2018 UP12_02820 afdfc132b771048094762b75f64dc315 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 153 174 - T 11-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 UP12_02820 afdfc132b771048094762b75f64dc315 324 Gene3D G3DSA:3.40.50.720 136 269 1.6E-82 T 11-10-2018 UP12_02820 afdfc132b771048094762b75f64dc315 324 SMART SM00829 15 318 1.1E-15 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_02820 afdfc132b771048094762b75f64dc315 324 SUPERFAMILY SSF50129 6 154 1.35E-28 T 11-10-2018 IPR011032 GroES-like superfamily UP12_03690 a182eb23b7374f432e26fafe8d24233f 399 Pfam PF05977 Transmembrane secretion effector 27 397 7.3E-14 T 11-10-2018 IPR010290 Transmembrane secretion effector UP12_03690 a182eb23b7374f432e26fafe8d24233f 399 Gene3D G3DSA:1.20.1250.20 5 394 2.4E-31 T 11-10-2018 UP12_03690 a182eb23b7374f432e26fafe8d24233f 399 SUPERFAMILY SSF103473 19 397 2.62E-36 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_03280 9391bda528de33cb08fade5f11b93003 242 Pfam PF02517 CAAX protease self-immunity 102 199 3.7E-14 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UP12_15185 1d6c927b46a708a2f8d1bdf9779f2ed1 353 SUPERFAMILY SSF53686 6 349 9.43E-107 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UP12_15185 1d6c927b46a708a2f8d1bdf9779f2ed1 353 TIGRFAM TIGR00260 thrC: threonine synthase 8 323 4.2E-112 T 11-10-2018 IPR004450 Threonine synthase-like UP12_15185 1d6c927b46a708a2f8d1bdf9779f2ed1 353 Gene3D G3DSA:3.40.50.1100 13 322 3.8E-124 T 11-10-2018 UP12_15185 1d6c927b46a708a2f8d1bdf9779f2ed1 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 316 2.4E-75 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UP12_15185 1d6c927b46a708a2f8d1bdf9779f2ed1 353 PIRSF PIRSF038945 1 349 4.6E-160 T 11-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 UP12_15185 1d6c927b46a708a2f8d1bdf9779f2ed1 353 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 UP12_15185 1d6c927b46a708a2f8d1bdf9779f2ed1 353 Gene3D G3DSA:3.40.50.1100 59 155 3.8E-124 T 11-10-2018 UP12_01320 af856464347e8884f777d4d3a4e93cd6 390 SUPERFAMILY SSF103473 3 378 3.79E-59 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01320 af856464347e8884f777d4d3a4e93cd6 390 Pfam PF07690 Major Facilitator Superfamily 9 315 9.8E-41 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_01320 af856464347e8884f777d4d3a4e93cd6 390 Gene3D G3DSA:1.20.1250.20 196 381 6.6E-18 T 11-10-2018 UP12_01320 af856464347e8884f777d4d3a4e93cd6 390 Gene3D G3DSA:1.20.1250.20 3 190 1.2E-29 T 11-10-2018 UP12_09030 f14f74fe93eca854747be1c51461c44f 88 SUPERFAMILY SSF52794 2 86 1.13E-19 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_09030 f14f74fe93eca854747be1c51461c44f 88 Gene3D G3DSA:3.40.50.2300 1 88 8.3E-21 T 11-10-2018 UP12_09030 f14f74fe93eca854747be1c51461c44f 88 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 85 5.4E-16 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_09560 b77d521303e93c7d34ddf40bda475ec2 453 PIRSF PIRSF006603 3 451 2.0E-67 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_09560 b77d521303e93c7d34ddf40bda475ec2 453 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 1.4E-102 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_09560 b77d521303e93c7d34ddf40bda475ec2 453 Pfam PF01554 MatE 20 180 4.4E-35 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_09560 b77d521303e93c7d34ddf40bda475ec2 453 Pfam PF01554 MatE 247 408 1.7E-36 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 11-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 557 3.2E-268 T 11-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 557 47.98 T 11-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 SUPERFAMILY SSF52016 377 556 1.49E-62 T 11-10-2018 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 Pfam PF00920 Dehydratase family 34 553 3.2E-230 T 11-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 11-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 Gene3D G3DSA:3.50.30.80 377 528 8.6E-54 T 11-10-2018 UP12_09810 d11805bde17d6b1341f1bfcd3346984b 558 SUPERFAMILY SSF143975 3 376 3.66E-142 T 11-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 UP12_07470 a490c782d9f53eead55a97cb8e09dc42 258 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_07470 a490c782d9f53eead55a97cb8e09dc42 258 Gene3D G3DSA:3.40.50.300 1 252 3.1E-57 T 11-10-2018 UP12_07470 a490c782d9f53eead55a97cb8e09dc42 258 SMART SM00382 27 220 1.5E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_07470 a490c782d9f53eead55a97cb8e09dc42 258 Pfam PF00005 ABC transporter 18 169 8.9E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_07470 a490c782d9f53eead55a97cb8e09dc42 258 SUPERFAMILY SSF52540 3 233 7.51E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 SMART SM00342 193 276 8.3E-30 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 Gene3D G3DSA:2.60.120.280 39 149 3.6E-7 T 11-10-2018 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 Pfam PF12833 Helix-turn-helix domain 199 277 2.9E-22 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 Gene3D G3DSA:1.10.10.60 174 234 8.3E-13 T 11-10-2018 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 230 272 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 SUPERFAMILY SSF46689 178 227 4.26E-8 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 Pfam PF02311 AraC-like ligand binding domain 35 157 2.4E-8 T 11-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 SUPERFAMILY SSF51215 45 161 8.63E-13 T 11-10-2018 IPR037923 Transcription regulator HTH-like UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 Gene3D G3DSA:1.10.10.2730 235 277 5.1E-17 T 11-10-2018 UP12_17840 5caa2449662d3c03a12585cc63bf83e9 281 SUPERFAMILY SSF46689 229 278 2.24E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_00660 54c8f97ee4697af68601683dcad887fa 232 PIRSF PIRSF002155 1 227 4.3E-81 T 11-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00660 54c8f97ee4697af68601683dcad887fa 232 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 44.714 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 UP12_00660 54c8f97ee4697af68601683dcad887fa 232 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 1.4E-56 T 11-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein UP12_00660 54c8f97ee4697af68601683dcad887fa 232 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 8.6E-108 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 UP12_00660 54c8f97ee4697af68601683dcad887fa 232 Gene3D G3DSA:3.40.50.790 68 159 2.0E-85 T 11-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich UP12_00660 54c8f97ee4697af68601683dcad887fa 232 Gene3D G3DSA:3.30.190.20 21 225 2.0E-85 T 11-10-2018 UP12_00660 54c8f97ee4697af68601683dcad887fa 232 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 11-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00660 54c8f97ee4697af68601683dcad887fa 232 SUPERFAMILY SSF56808 6 226 4.58E-85 T 11-10-2018 IPR023674 Ribosomal protein L1-like UP12_07345 c7088231ecb9e79529e23cdbdced27e0 115 Hamap MF_00910 Cell division protein FtsL [ftsL]. 34 115 12.674 T 11-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 UP12_07345 c7088231ecb9e79529e23cdbdced27e0 115 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 34 113 4.3E-16 T 11-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 UP12_08080 e8897376b5050d26337c70191fd8b366 565 Gene3D G3DSA:3.30.930.10 11 463 4.6E-252 T 11-10-2018 UP12_08080 e8897376b5050d26337c70191fd8b366 565 Pfam PF04073 Aminoacyl-tRNA editing domain 258 373 3.1E-29 T 11-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UP12_08080 e8897376b5050d26337c70191fd8b366 565 Pfam PF03129 Anticodon binding domain 477 564 1.2E-18 T 11-10-2018 IPR004154 Anticodon-binding UP12_08080 e8897376b5050d26337c70191fd8b366 565 SUPERFAMILY SSF55681 9 475 1.19E-100 T 11-10-2018 UP12_08080 e8897376b5050d26337c70191fd8b366 565 Gene3D G3DSA:3.40.50.800 4 551 4.6E-252 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily UP12_08080 e8897376b5050d26337c70191fd8b366 565 Gene3D G3DSA:3.90.960.10 240 387 4.6E-252 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UP12_08080 e8897376b5050d26337c70191fd8b366 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 4.1E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_08080 e8897376b5050d26337c70191fd8b366 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 4.1E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_08080 e8897376b5050d26337c70191fd8b366 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 4.1E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_08080 e8897376b5050d26337c70191fd8b366 565 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 4.1E-19 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 UP12_08080 e8897376b5050d26337c70191fd8b366 565 SUPERFAMILY SSF55826 218 386 1.11E-34 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UP12_08080 e8897376b5050d26337c70191fd8b366 565 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 563 1.6E-245 T 11-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 UP12_08080 e8897376b5050d26337c70191fd8b366 565 PIRSF PIRSF001535 1 565 3.3E-259 T 11-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 UP12_08080 e8897376b5050d26337c70191fd8b366 565 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 457 8.4E-56 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_08080 e8897376b5050d26337c70191fd8b366 565 SUPERFAMILY SSF52954 461 564 1.43E-27 T 11-10-2018 UP12_08080 e8897376b5050d26337c70191fd8b366 565 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 565 41.074 T 11-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 UP12_01490 c29cf322d177dca3bbfe4fa0317e491e 179 SUPERFAMILY SSF159234 35 137 1.07E-24 T 11-10-2018 IPR035930 FomD-like superfamily UP12_01490 c29cf322d177dca3bbfe4fa0317e491e 179 Pfam PF04167 Protein of unknown function (DUF402) 66 131 4.9E-13 T 11-10-2018 IPR007295 Domain of unknown function DUF402 UP12_15290 7ea844d9e70e7a317940c70eefa6adf8 247 Pfam PF06276 Ferric iron reductase FhuF-like transporter 58 206 1.1E-12 T 11-10-2018 IPR022770 Ferric iron reductase FhuF domain UP12_15290 7ea844d9e70e7a317940c70eefa6adf8 247 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 214 238 4.4E-5 T 11-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 SUPERFAMILY SSF58104 316 652 1.03E-65 T 11-10-2018 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 Gene3D G3DSA:1.20.1480.50 265 354 4.1E-18 T 11-10-2018 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 Gene3D G3DSA:3.30.450.20 90 182 1.0E-37 T 11-10-2018 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 SMART SM00304 296 348 1.2E-14 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 Gene3D G3DSA:3.30.450.20 183 264 1.0E-37 T 11-10-2018 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 SUPERFAMILY SSF103190 102 192 5.49E-9 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_06725 a925c68585687919ae1372f1c3127b8c 653 SMART SM00283 377 652 2.8E-67 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 Pfam PF00672 HAMP domain 296 344 2.0E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 Pfam PF02743 Cache domain 36 259 9.9E-31 T 11-10-2018 IPR033479 Double Cache domain 1 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 Gene3D G3DSA:1.10.287.950 375 652 8.4E-60 T 11-10-2018 UP12_06725 a925c68585687919ae1372f1c3127b8c 653 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 444 605 1.4E-36 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_02985 e6d4b5d4984f78517e321bb6aa694129 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 11-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 UP12_02985 e6d4b5d4984f78517e321bb6aa694129 131 SUPERFAMILY SSF54593 1 121 3.85E-23 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_02985 e6d4b5d4984f78517e321bb6aa694129 131 Gene3D G3DSA:3.10.180.10 6 128 6.9E-36 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_02985 e6d4b5d4984f78517e321bb6aa694129 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 121 1.2E-8 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_13460 0c2ff7f4680f42fc2ae88d7ca107124b 106 Pfam PF00085 Thioredoxin 8 101 2.1E-17 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 UP12_13460 0c2ff7f4680f42fc2ae88d7ca107124b 106 Gene3D G3DSA:3.40.30.10 1 104 8.4E-24 T 11-10-2018 UP12_13460 0c2ff7f4680f42fc2ae88d7ca107124b 106 SUPERFAMILY SSF52833 2 102 1.45E-26 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 Pfam PF03990 Domain of unknown function (DUF348) 97 135 1.5E-11 T 11-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 Pfam PF03990 Domain of unknown function (DUF348) 154 193 1.8E-13 T 11-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 Pfam PF03990 Domain of unknown function (DUF348) 40 80 4.0E-13 T 11-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 SMART SM01208 208 286 1.3E-23 T 11-10-2018 IPR011098 G5 domain UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 Gene3D G3DSA:2.20.230.10 209 286 3.7E-15 T 11-10-2018 UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 Pfam PF07501 G5 domain 213 285 8.4E-17 T 11-10-2018 IPR011098 G5 domain UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 Pfam PF06725 3D domain 339 399 5.2E-22 T 11-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 UP12_00265 a15bffe102c0ab4f5d2d54f1fb194b48 400 SUPERFAMILY SSF50685 341 389 5.58E-9 T 11-10-2018 IPR036908 RlpA-like domain superfamily UP12_13690 9ceff21ed687d3fb9ee2810661de4168 292 SMART SM00382 26 203 2.4E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_13690 9ceff21ed687d3fb9ee2810661de4168 292 Gene3D G3DSA:3.40.50.300 1 238 3.2E-43 T 11-10-2018 UP12_13690 9ceff21ed687d3fb9ee2810661de4168 292 SUPERFAMILY SSF52540 2 218 2.31E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13690 9ceff21ed687d3fb9ee2810661de4168 292 Pfam PF00005 ABC transporter 17 154 5.6E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17200 2d54912215dc3ac4f49f44455047b525 173 Hamap MF_01398 ATP synthase subunit b [atpF]. 14 151 13.347 T 11-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UP12_17200 2d54912215dc3ac4f49f44455047b525 173 Pfam PF00430 ATP synthase B/B' CF(0) 21 150 3.2E-38 T 11-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 UP12_17200 2d54912215dc3ac4f49f44455047b525 173 SUPERFAMILY SSF81573 77 134 2.09E-9 T 11-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily UP12_17200 2d54912215dc3ac4f49f44455047b525 173 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 23 168 2.0E-45 T 11-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 UP12_12635 bd25248876c764c689e6f91188eb9f2c 431 Gene3D G3DSA:3.30.2320.10 264 404 2.2E-25 T 11-10-2018 UP12_12635 bd25248876c764c689e6f91188eb9f2c 431 Gene3D G3DSA:3.30.2400.10 184 399 2.2E-25 T 11-10-2018 UP12_12635 bd25248876c764c689e6f91188eb9f2c 431 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 408 2.2E-83 T 11-10-2018 IPR024455 Phage capsid UP12_12635 bd25248876c764c689e6f91188eb9f2c 431 Pfam PF05065 Phage capsid family 134 408 2.8E-63 T 11-10-2018 IPR024455 Phage capsid UP12_12635 bd25248876c764c689e6f91188eb9f2c 431 SUPERFAMILY SSF56563 127 408 3.27E-63 T 11-10-2018 UP12_10950 9d97cacb9a41707a8a0c9376e4838ea7 578 PIRSF PIRSF003128 1 574 2.6E-189 T 11-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 UP12_10950 9d97cacb9a41707a8a0c9376e4838ea7 578 SUPERFAMILY SSF52540 1 219 7.73E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10950 9d97cacb9a41707a8a0c9376e4838ea7 578 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 524 3.5E-15 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal UP12_10950 9d97cacb9a41707a8a0c9376e4838ea7 578 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 569 8.1E-205 T 11-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 UP12_10950 9d97cacb9a41707a8a0c9376e4838ea7 578 Gene3D G3DSA:3.40.50.300 1 234 1.2E-42 T 11-10-2018 UP12_10950 9d97cacb9a41707a8a0c9376e4838ea7 578 Gene3D G3DSA:3.40.50.300 249 570 3.0E-54 T 11-10-2018 UP12_10950 9d97cacb9a41707a8a0c9376e4838ea7 578 SUPERFAMILY SSF52540 4 524 7.88E-28 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16695 f94a9ae43d054102050eddd2a428055b 379 Gene3D G3DSA:3.40.50.2000 6 361 4.9E-154 T 11-10-2018 UP12_16695 f94a9ae43d054102050eddd2a428055b 379 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 363 3.5E-123 T 11-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_16695 f94a9ae43d054102050eddd2a428055b 379 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 365 8.8E-171 T 11-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 UP12_16695 f94a9ae43d054102050eddd2a428055b 379 SUPERFAMILY SSF53756 4 367 8.07E-136 T 11-10-2018 UP12_16695 f94a9ae43d054102050eddd2a428055b 379 Gene3D G3DSA:3.40.50.2000 191 351 4.9E-154 T 11-10-2018 UP12_00675 f0ab226e4283a914e9ecb53e983dcf6f 201 SUPERFAMILY SSF53335 7 200 2.04E-37 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_00675 f0ab226e4283a914e9ecb53e983dcf6f 201 Pfam PF05175 Methyltransferase small domain 28 197 1.8E-50 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 UP12_00675 f0ab226e4283a914e9ecb53e983dcf6f 201 Gene3D G3DSA:3.40.50.150 6 201 6.1E-47 T 11-10-2018 UP12_14105 92e1205317f0a7fb97d7f78e4580a362 489 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 6 474 2.2E-232 T 11-10-2018 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494 UP12_14105 92e1205317f0a7fb97d7f78e4580a362 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UP12_14105 92e1205317f0a7fb97d7f78e4580a362 489 SUPERFAMILY SSF53720 4 480 1.03E-174 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_14105 92e1205317f0a7fb97d7f78e4580a362 489 Pfam PF00171 Aldehyde dehydrogenase family 11 476 4.8E-183 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_14105 92e1205317f0a7fb97d7f78e4580a362 489 Gene3D G3DSA:3.40.605.10 10 471 5.2E-196 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_14105 92e1205317f0a7fb97d7f78e4580a362 489 Gene3D G3DSA:3.40.309.10 253 446 5.2E-196 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_14105 92e1205317f0a7fb97d7f78e4580a362 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UP12_00305 2fba3cfd43318c6124019510e19c2a28 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 100 118 - T 11-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 UP12_00305 2fba3cfd43318c6124019510e19c2a28 125 SUPERFAMILY SSF55298 2 124 4.24E-48 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_00305 2fba3cfd43318c6124019510e19c2a28 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 123 5.7E-56 T 11-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 UP12_00305 2fba3cfd43318c6124019510e19c2a28 125 Gene3D G3DSA:3.30.1330.40 2 125 9.8E-57 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_00305 2fba3cfd43318c6124019510e19c2a28 125 Pfam PF01042 Endoribonuclease L-PSP 7 123 7.0E-48 T 11-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Gene3D G3DSA:3.40.50.2300 408 496 1.7E-6 T 11-10-2018 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 SUPERFAMILY SSF55804 501 640 5.23E-27 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Pfam PF00874 PRD domain 309 397 6.4E-21 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Pfam PF00874 PRD domain 197 281 1.2E-16 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 SUPERFAMILY SSF52794 408 484 4.39E-5 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Gene3D G3DSA:1.10.1790.10 187 283 1.6E-14 T 11-10-2018 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Gene3D G3DSA:1.10.1790.10 299 399 1.9E-23 T 11-10-2018 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Pfam PF08279 HTH domain 5 62 1.2E-10 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 SUPERFAMILY SSF63520 298 401 1.05E-22 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 503 639 1.0E-26 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 SUPERFAMILY SSF63520 180 281 1.7E-19 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Gene3D G3DSA:1.10.10.10 2 152 6.8E-15 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Gene3D G3DSA:3.40.930.10 500 641 7.0E-23 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_18005 54d3ce28e54573cf890d2f1cc3a418f1 647 Pfam PF05043 Mga helix-turn-helix domain 91 166 9.6E-17 T 11-10-2018 IPR007737 Mga helix-turn-helix domain UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 Pfam PF03462 PCRF domain 1 179 1.5E-61 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 205 221 - T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 326 37.421 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 SMART SM00937 45 155 2.4E-59 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 Pfam PF00472 RF-1 domain 189 298 6.1E-43 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 SUPERFAMILY SSF75620 1 324 4.71E-135 T 11-10-2018 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 325 2.9E-172 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 Gene3D G3DSA:3.30.160.20 186 281 1.8E-98 T 11-10-2018 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 Gene3D G3DSA:1.20.58.410 1 83 9.6E-16 T 11-10-2018 UP12_16495 6fb6c5ce149703d0f3895970d666bd75 327 Gene3D G3DSA:3.30.70.1660 90 319 1.8E-98 T 11-10-2018 UP12_02795 51360a6451dcb8abf9039f43783ed4ff 325 SUPERFAMILY SSF54001 204 324 1.96E-39 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_02795 51360a6451dcb8abf9039f43783ed4ff 325 Pfam PF00877 NlpC/P60 family 216 320 5.3E-31 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_02795 51360a6451dcb8abf9039f43783ed4ff 325 Gene3D G3DSA:1.10.530.10 47 189 6.9E-48 T 11-10-2018 UP12_02795 51360a6451dcb8abf9039f43783ed4ff 325 SUPERFAMILY SSF53955 55 188 2.73E-13 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_02795 51360a6451dcb8abf9039f43783ed4ff 325 Gene3D G3DSA:3.90.1720.10 194 325 3.1E-44 T 11-10-2018 UP12_02795 51360a6451dcb8abf9039f43783ed4ff 325 Pfam PF13702 Lysozyme-like 51 187 2.4E-40 T 11-10-2018 UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 SUPERFAMILY SSF47060 3 89 5.59E-37 T 11-10-2018 IPR009068 S15/NS1, RNA-binding UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 88 5.0E-37 T 11-10-2018 UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 Gene3D G3DSA:1.10.287.10 2 89 7.1E-38 T 11-10-2018 UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.284 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 Pfam PF00312 Ribosomal protein S15 8 88 1.1E-38 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 SMART SM01387 8 88 1.2E-52 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_08155 5f2ac426efaa7e0755997fa1cb92bacd 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 2.6E-42 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 217 233 2.7E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 315 327 2.7E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 SUPERFAMILY SSF53092 1 135 1.4E-32 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 Gene3D G3DSA:3.40.350.10 1 135 2.2E-38 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 Gene3D G3DSA:3.90.230.10 136 361 4.5E-80 T 11-10-2018 UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 Pfam PF00557 Metallopeptidase family M24 146 347 2.9E-63 T 11-10-2018 IPR000994 Peptidase M24 UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 SUPERFAMILY SSF55920 136 363 9.94E-78 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 293 305 - T 11-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site UP12_06685 0c27587c97759fa2b74b0060e6fd5608 364 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 137 2.6E-25 T 11-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 Gene3D G3DSA:1.20.1250.20 2 444 3.5E-135 T 11-10-2018 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 11 437 2.2E-115 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 Pfam PF00083 Sugar (and other) transporter 12 440 1.9E-121 T 11-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 ProSitePatterns PS00216 Sugar transport proteins signature 1. 297 313 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 SUPERFAMILY SSF103473 6 440 3.79E-83 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 PRINTS PR00171 Sugar transporter signature 342 363 2.5E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 PRINTS PR00171 Sugar transporter signature 253 263 2.5E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 PRINTS PR00171 Sugar transporter signature 365 377 2.5E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 PRINTS PR00171 Sugar transporter signature 101 120 2.5E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_16835 9f8fdc51470853f4c6acea4e5b1d7868 456 PRINTS PR00171 Sugar transporter signature 18 28 2.5E-25 T 11-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 UP12_09800 d6ce39f1e8d6c465b2c63a5760275a10 262 Pfam PF04445 Putative SAM-dependent methyltransferase 75 250 8.1E-19 T 11-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 UP12_09800 d6ce39f1e8d6c465b2c63a5760275a10 262 SUPERFAMILY SSF53335 3 257 4.93E-60 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_09800 d6ce39f1e8d6c465b2c63a5760275a10 262 Gene3D G3DSA:3.40.50.150 66 260 1.2E-43 T 11-10-2018 UP12_18985 deb0250272dcf201269a5b2560bca096 539 Gene3D G3DSA:3.30.300.310 433 537 1.4E-30 T 11-10-2018 UP12_18985 deb0250272dcf201269a5b2560bca096 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_18985 deb0250272dcf201269a5b2560bca096 539 SUPERFAMILY SSF56801 5 531 5.1E-135 T 11-10-2018 UP12_18985 deb0250272dcf201269a5b2560bca096 539 Pfam PF00501 AMP-binding enzyme 32 437 4.6E-82 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_18985 deb0250272dcf201269a5b2560bca096 539 Gene3D G3DSA:3.40.50.980 182 355 6.0E-58 T 11-10-2018 UP12_18985 deb0250272dcf201269a5b2560bca096 539 TIGRFAM TIGR02275 DHB_AMP_lig: (2,3-dihydroxybenzoyl)adenylate synthase 7 529 7.1E-235 T 11-10-2018 IPR011963 2,3-dihydroxybenzoate-AMP ligase GO:0008668|GO:0019290 UP12_18985 deb0250272dcf201269a5b2560bca096 539 Gene3D G3DSA:3.40.50.980 22 179 3.6E-50 T 11-10-2018 UP12_18985 deb0250272dcf201269a5b2560bca096 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 522 1.2E-13 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_18985 deb0250272dcf201269a5b2560bca096 539 Gene3D G3DSA:2.30.38.10 356 431 8.5E-29 T 11-10-2018 UP12_03265 2279c42393a26cd36fd3a3f8bc4111a3 734 SMART SM00460 472 547 7.4E-18 T 11-10-2018 IPR002931 Transglutaminase-like UP12_03265 2279c42393a26cd36fd3a3f8bc4111a3 734 SUPERFAMILY SSF54001 399 555 4.42E-41 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_03265 2279c42393a26cd36fd3a3f8bc4111a3 734 Gene3D G3DSA:3.10.620.30 385 576 1.1E-22 T 11-10-2018 UP12_03265 2279c42393a26cd36fd3a3f8bc4111a3 734 Pfam PF01841 Transglutaminase-like superfamily 423 545 1.1E-26 T 11-10-2018 IPR002931 Transglutaminase-like UP12_03265 2279c42393a26cd36fd3a3f8bc4111a3 734 Pfam PF13559 Domain of unknown function (DUF4129) 662 715 6.5E-9 T 11-10-2018 IPR025403 Domain of unknown function DUF4129 UP12_14815 f73928351461eb89687dc80bbdaae92a 397 Pfam PF00155 Aminotransferase class I and II 30 373 2.7E-68 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_14815 f73928351461eb89687dc80bbdaae92a 397 Gene3D G3DSA:3.40.640.10 61 282 8.7E-128 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_14815 f73928351461eb89687dc80bbdaae92a 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 232 245 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UP12_14815 f73928351461eb89687dc80bbdaae92a 397 SUPERFAMILY SSF53383 5 385 6.65E-118 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_14815 f73928351461eb89687dc80bbdaae92a 397 Gene3D G3DSA:3.90.1150.10 30 378 8.7E-128 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 SUPERFAMILY SSF69864 171 398 4.05E-95 T 11-10-2018 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 Gene3D G3DSA:3.90.1260.10 175 402 6.7E-94 T 11-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 117 128 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 Gene3D G3DSA:3.40.50.620 1 174 5.8E-69 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 Pfam PF00764 Arginosuccinate synthase 8 392 1.2E-183 T 11-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 394 4.2E-179 T 11-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 SUPERFAMILY SSF52402 3 171 1.17E-49 T 11-10-2018 UP12_13185 e36eda8dd57ebe53e5f09ed6fa788a02 403 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 397 55.654 T 11-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 UP12_05660 70086f58095c71a85b556262424c1a74 340 Pfam PF00005 ABC transporter 47 198 7.7E-36 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_05660 70086f58095c71a85b556262424c1a74 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 317 3.2E-17 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_05660 70086f58095c71a85b556262424c1a74 340 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_05660 70086f58095c71a85b556262424c1a74 340 SMART SM00382 55 248 4.5E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_05660 70086f58095c71a85b556262424c1a74 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 337 4.0E-27 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_05660 70086f58095c71a85b556262424c1a74 340 Gene3D G3DSA:3.40.50.300 17 340 1.0E-101 T 11-10-2018 UP12_05660 70086f58095c71a85b556262424c1a74 340 SUPERFAMILY SSF52540 19 270 1.3E-74 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Pfam PF00698 Acyl transferase domain 519 820 1.4E-48 T 11-10-2018 IPR014043 Acyl transferase UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 383 494 9.4E-23 T 11-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Gene3D G3DSA:3.30.70.250 651 711 1.9E-123 T 11-10-2018 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SUPERFAMILY SSF55048 650 710 1.83E-5 T 11-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Pfam PF08659 KR domain 1124 1315 2.6E-49 T 11-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Gene3D G3DSA:3.40.366.10 517 822 1.9E-123 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Gene3D G3DSA:1.10.1200.10 1379 1470 3.5E-10 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SUPERFAMILY SSF47336 1403 1462 2.88E-10 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SUPERFAMILY SSF51735 1121 1368 1.73E-35 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Gene3D G3DSA:3.40.50.720 887 1374 2.5E-95 T 11-10-2018 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1124 1317 4.6E-42 T 11-10-2018 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 256 2.0E-72 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 521 820 1.8E-78 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SUPERFAMILY SSF51735 897 1104 1.58E-13 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SMART SM00825 Beta-ketoacyl synthase 9 433 7.2E-177 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Gene3D G3DSA:3.30.70.3290 447 852 1.9E-123 T 11-10-2018 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Gene3D G3DSA:3.40.47.10 6 433 2.7E-159 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Pfam PF00550 Phosphopantetheine attachment site 1410 1461 2.1E-10 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 380 3.7E-42 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SMART SM00823 Phosphopantetheine attachment site 1398 1466 3.6E-4 T 11-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SUPERFAMILY SSF52151 518 804 1.67E-63 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase UP12_03540 0c839c75aeb6ee8fe3ac1177385fc502 1500 SUPERFAMILY SSF53901 8 379 2.67E-83 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 10 471 1.5E-228 T 11-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 Pfam PF00206 Lyase 17 346 6.7E-112 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 Gene3D G3DSA:1.10.275.10 10 143 2.6E-57 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 Gene3D G3DSA:1.20.200.10 144 411 2.1E-112 T 11-10-2018 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 SUPERFAMILY SSF48557 10 466 6.91E-146 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 PRINTS PR00145 Argininosuccinate lyase family signature 321 337 1.8E-5 T 11-10-2018 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 PRINTS PR00145 Argininosuccinate lyase family signature 179 199 1.8E-5 T 11-10-2018 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 Pfam PF10415 Fumarase C C-terminus 413 465 8.1E-19 T 11-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 PRINTS PR00149 Fumarate lyase superfamily signature 184 202 6.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 6.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 PRINTS PR00149 Fumarate lyase superfamily signature 321 337 6.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 PRINTS PR00149 Fumarate lyase superfamily signature 275 302 6.9E-32 T 11-10-2018 IPR000362 Fumarate lyase family UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 ProSitePatterns PS00163 Fumarate lyases signature. 321 330 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UP12_15755 85530af5a0f62fe4787c8dcbd6908d7f 481 Gene3D G3DSA:1.10.40.30 412 463 4.9E-21 T 11-10-2018 UP12_18425 949c01985983100feb5223fa07775a44 335 Pfam PF00196 Bacterial regulatory proteins, luxR family 278 329 4.4E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_18425 949c01985983100feb5223fa07775a44 335 Gene3D G3DSA:1.10.10.10 246 335 3.4E-17 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18425 949c01985983100feb5223fa07775a44 335 SMART SM00421 275 332 1.2E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_18425 949c01985983100feb5223fa07775a44 335 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 278 292 5.4E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_18425 949c01985983100feb5223fa07775a44 335 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 292 308 5.4E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_18425 949c01985983100feb5223fa07775a44 335 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 308 320 5.4E-10 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_18425 949c01985983100feb5223fa07775a44 335 SUPERFAMILY SSF46894 264 332 6.8E-16 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_18425 949c01985983100feb5223fa07775a44 335 ProSitePatterns PS00622 LuxR-type HTH domain signature. 292 319 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_18425 949c01985983100feb5223fa07775a44 335 Gene3D G3DSA:3.30.450.40 3 152 1.5E-6 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 Gene3D G3DSA:1.10.10.60 1 65 2.3E-26 T 11-10-2018 UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 SUPERFAMILY SSF46689 2 81 5.82E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 Gene3D G3DSA:1.10.357.10 66 193 5.9E-19 T 11-10-2018 UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.5E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.5E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 SUPERFAMILY SSF48498 79 192 5.93E-20 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_10490 7b35dde100ef03aed55af4aeeee3956e 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.1E-13 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 Gene3D G3DSA:1.25.40.10 1 377 1.1E-107 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 SUPERFAMILY SSF48452 82 323 2.66E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 Pfam PF13174 Tetratricopeptide repeat 221 244 0.026 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 SMART SM00028 335 368 180.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 SMART SM00028 219 252 0.0093 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 SMART SM00028 179 212 2.3 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 SMART SM00028 138 171 42.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06070 41edad3b50b6ebd036968d187283dfab 377 Pfam PF13181 Tetratricopeptide repeat 342 363 0.061 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_13720 e20d078ddcdbc0cfd8912db0725bc185 359 Pfam PF10776 Protein of unknown function (DUF2600) 20 348 7.5E-154 T 11-10-2018 IPR019712 Protein of unknown function DUF2600 UP12_10115 01b536267b4a63d86ecd00b37ed00e87 224 PIRSF PIRSF000032 2 224 2.5E-104 T 11-10-2018 UP12_10115 01b536267b4a63d86ecd00b37ed00e87 224 SUPERFAMILY SSF81342 6 224 3.3E-61 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 UP12_10115 01b536267b4a63d86ecd00b37ed00e87 224 Gene3D G3DSA:1.20.810.10 1 224 1.2E-89 T 11-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 UP12_10115 01b536267b4a63d86ecd00b37ed00e87 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 4.9E-49 T 11-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 SMART SM00490 260 341 1.2E-28 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 Pfam PF00270 DEAD/DEAH box helicase 28 196 6.7E-46 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 Gene3D G3DSA:3.40.50.300 217 438 2.7E-44 T 11-10-2018 UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 SMART SM00487 23 224 1.5E-55 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 4 438 48.94 T 11-10-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 Pfam PF00271 Helicase conserved C-terminal domain 232 341 7.5E-27 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 SUPERFAMILY SSF52540 72 362 3.69E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11400 3d6eb7429e9faf6540d0207f27cee9af 439 Gene3D G3DSA:3.40.50.300 2 216 9.5E-68 T 11-10-2018 UP12_18160 9cdf29d21b24475b64297f7af92d64c9 354 Gene3D G3DSA:3.20.20.150 1 354 3.6E-136 T 11-10-2018 UP12_18160 9cdf29d21b24475b64297f7af92d64c9 354 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 354 144.434 T 11-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 UP12_18160 9cdf29d21b24475b64297f7af92d64c9 354 SUPERFAMILY SSF51658 1 341 2.68E-76 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily UP12_18160 9cdf29d21b24475b64297f7af92d64c9 354 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 343 2.2E-136 T 11-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 UP12_18160 9cdf29d21b24475b64297f7af92d64c9 354 PIRSF PIRSF016049 143 350 1.6E-72 T 11-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 UP12_18160 9cdf29d21b24475b64297f7af92d64c9 354 PIRSF PIRSF016049 1 142 7.0E-41 T 11-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 UP12_06890 6b6540863a4ad8bf83a2018f90c2aedc 180 Pfam PF00578 AhpC/TSA family 6 141 4.7E-38 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_06890 6b6540863a4ad8bf83a2018f90c2aedc 180 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 164 180 1.1E-4 T 11-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_06890 6b6540863a4ad8bf83a2018f90c2aedc 180 Gene3D G3DSA:3.40.30.10 1 180 1.1E-71 T 11-10-2018 UP12_06890 6b6540863a4ad8bf83a2018f90c2aedc 180 PIRSF PIRSF000239 1 180 9.7E-58 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_06890 6b6540863a4ad8bf83a2018f90c2aedc 180 SUPERFAMILY SSF52833 6 179 6.87E-57 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_15510 c192490dd9c9f8e21dd7138e022caf1e 292 SUPERFAMILY SSF46689 5 69 4.03E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_15510 c192490dd9c9f8e21dd7138e022caf1e 292 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.5E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_15510 c192490dd9c9f8e21dd7138e022caf1e 292 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.5E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_15510 c192490dd9c9f8e21dd7138e022caf1e 292 Gene3D G3DSA:1.10.357.10 1 194 8.3E-30 T 11-10-2018 UP12_15510 c192490dd9c9f8e21dd7138e022caf1e 292 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 2.5E-18 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_17660 d86007e0fa9fe98fe78f992101d33359 246 Pfam PF02348 Cytidylyltransferase 7 208 5.1E-35 T 11-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 UP12_17660 d86007e0fa9fe98fe78f992101d33359 246 SUPERFAMILY SSF53448 4 209 2.93E-27 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_17660 d86007e0fa9fe98fe78f992101d33359 246 Gene3D G3DSA:3.90.550.10 3 214 1.2E-33 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_12255 b16fbb948e2e1d002f06444359096ca4 289 Pfam PF02163 Peptidase family M50 113 150 1.2E-7 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 UP12_12255 b16fbb948e2e1d002f06444359096ca4 289 Pfam PF02163 Peptidase family M50 33 105 1.6E-6 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 UP12_15370 7b20276f55ae39ed570db97a9152225a 190 SUPERFAMILY SSF116734 2 190 1.8E-20 T 11-10-2018 UP12_15370 7b20276f55ae39ed570db97a9152225a 190 Pfam PF01420 Type I restriction modification DNA specificity domain 2 157 3.2E-7 T 11-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 UP12_15370 7b20276f55ae39ed570db97a9152225a 190 Gene3D G3DSA:3.90.220.20 2 190 4.0E-23 T 11-10-2018 UP12_12040 bb4a14849e1d3ee8e807c9d2c85441fd 380 Pfam PF00266 Aminotransferase class-V 4 365 6.5E-86 T 11-10-2018 IPR000192 Aminotransferase class V domain UP12_12040 bb4a14849e1d3ee8e807c9d2c85441fd 380 PIRSF PIRSF005572 1 380 1.6E-128 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 UP12_12040 bb4a14849e1d3ee8e807c9d2c85441fd 380 SUPERFAMILY SSF53383 3 377 6.05E-106 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_12040 bb4a14849e1d3ee8e807c9d2c85441fd 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UP12_12040 bb4a14849e1d3ee8e807c9d2c85441fd 380 Gene3D G3DSA:3.40.640.10 61 235 2.6E-144 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_12040 bb4a14849e1d3ee8e807c9d2c85441fd 380 Gene3D G3DSA:1.10.260.50 15 279 2.6E-144 T 11-10-2018 UP12_12040 bb4a14849e1d3ee8e807c9d2c85441fd 380 Gene3D G3DSA:3.90.1150.10 4 371 2.6E-144 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Pfam PF02817 e3 binding domain 122 157 3.8E-12 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Pfam PF02817 e3 binding domain 169 202 3.3E-10 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 SUPERFAMILY SSF47005 116 161 1.31E-10 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Gene3D G3DSA:3.30.559.10 212 440 1.2E-87 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Gene3D G3DSA:4.10.320.10 163 207 1.7E-12 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 SUPERFAMILY SSF52777 212 440 1.33E-82 T 11-10-2018 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Pfam PF00364 Biotin-requiring enzyme 4 76 1.7E-11 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 SUPERFAMILY SSF47005 161 205 1.14E-9 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Gene3D G3DSA:2.40.50.100 1 104 9.5E-25 T 11-10-2018 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 213 440 4.7E-85 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 SUPERFAMILY SSF51230 1 93 1.57E-22 T 11-10-2018 IPR011053 Single hybrid motif UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 SMART SM01059 229 429 0.0029 T 11-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 UP12_06225 31f90cd36d38fdd21f0699ee1d30aa23 440 Gene3D G3DSA:4.10.320.10 110 162 3.9E-16 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_12225 393f524446b0b89c339e3c0c1b9e9b7f 147 Hamap MF_00707 UPF0735 ACT domain-containing protein . 2 146 31.711 T 11-10-2018 IPR008310 UPF0735 ACT domain-containing protein UP12_12225 393f524446b0b89c339e3c0c1b9e9b7f 147 PIRSF PIRSF025624 1 146 1.9E-61 T 11-10-2018 IPR008310 UPF0735 ACT domain-containing protein UP12_12225 393f524446b0b89c339e3c0c1b9e9b7f 147 Gene3D G3DSA:3.30.70.260 69 144 7.5E-8 T 11-10-2018 UP12_12225 393f524446b0b89c339e3c0c1b9e9b7f 147 SUPERFAMILY SSF55021 70 143 2.19E-12 T 11-10-2018 UP12_12225 393f524446b0b89c339e3c0c1b9e9b7f 147 Pfam PF01842 ACT domain 70 135 9.8E-11 T 11-10-2018 IPR002912 ACT domain UP12_13675 4e7515ffea8e84eda48ca18ad8fe84d7 436 Pfam PF02687 FtsX-like permease family 324 427 1.9E-12 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UP12_13675 4e7515ffea8e84eda48ca18ad8fe84d7 436 Pfam PF12704 MacB-like periplasmic core domain 22 234 2.8E-8 T 11-10-2018 IPR025857 MacB-like periplasmic core domain UP12_15540 9dddbcd708f807982860c99167ab6534 211 SUPERFAMILY SSF52172 1 119 1.99E-31 T 11-10-2018 IPR011006 CheY-like superfamily UP12_15540 9dddbcd708f807982860c99167ab6534 211 Gene3D G3DSA:3.40.50.12740 2 210 2.2E-70 T 11-10-2018 UP12_15540 9dddbcd708f807982860c99167ab6534 211 SMART SM00448 2 115 8.6E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_15540 9dddbcd708f807982860c99167ab6534 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 1.8E-22 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_15540 9dddbcd708f807982860c99167ab6534 211 Pfam PF00072 Response regulator receiver domain 4 115 5.1E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_15540 9dddbcd708f807982860c99167ab6534 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.7E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_15540 9dddbcd708f807982860c99167ab6534 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.7E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_15540 9dddbcd708f807982860c99167ab6534 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.7E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_15540 9dddbcd708f807982860c99167ab6534 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_15540 9dddbcd708f807982860c99167ab6534 211 SUPERFAMILY SSF46894 144 210 2.04E-23 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_15540 9dddbcd708f807982860c99167ab6534 211 SMART SM00421 147 204 5.9E-29 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_13800 895da0b414d021287af6d8d7396e20c4 217 Pfam PF02342 TerD domain 33 213 6.4E-61 T 11-10-2018 IPR003325 TerD domain UP12_13800 895da0b414d021287af6d8d7396e20c4 217 Gene3D G3DSA:2.60.60.30 48 211 1.4E-49 T 11-10-2018 UP12_16790 ba2466e86437285f3dd1a69cec95a55e 199 SUPERFAMILY SSF51569 8 188 1.48E-53 T 11-10-2018 UP12_16790 ba2466e86437285f3dd1a69cec95a55e 199 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 188 1.5E-57 T 11-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UP12_16790 ba2466e86437285f3dd1a69cec95a55e 199 Gene3D G3DSA:3.20.20.70 3 198 8.7E-61 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_16790 ba2466e86437285f3dd1a69cec95a55e 199 Pfam PF01081 KDPG and KHG aldolase 9 194 2.4E-56 T 11-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UP12_16790 ba2466e86437285f3dd1a69cec95a55e 199 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 11-10-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 UP12_06330 6a1edd8ea7d8497062931f603916dc76 108 Gene3D G3DSA:1.10.10.10 1 108 1.1E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06330 6a1edd8ea7d8497062931f603916dc76 108 SUPERFAMILY SSF46785 12 104 5.93E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06330 6a1edd8ea7d8497062931f603916dc76 108 Pfam PF03551 Transcriptional regulator PadR-like family 16 86 9.4E-24 T 11-10-2018 IPR005149 Transcription regulator PadR, N-terminal UP12_07315 0760cfe8649b6b29c1a2d68a9d5c4d43 179 SMART SM00717 5 59 0.0059 T 11-10-2018 IPR001005 SANT/Myb domain UP12_07315 0760cfe8649b6b29c1a2d68a9d5c4d43 179 SUPERFAMILY SSF46689 7 62 2.18E-5 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_07315 0760cfe8649b6b29c1a2d68a9d5c4d43 179 Pfam PF13921 Myb-like DNA-binding domain 9 61 1.3E-5 T 11-10-2018 UP12_07315 0760cfe8649b6b29c1a2d68a9d5c4d43 179 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 4 78 9.5E-44 T 11-10-2018 IPR014243 Transcription factor, RsfA UP12_07315 0760cfe8649b6b29c1a2d68a9d5c4d43 179 Gene3D G3DSA:1.10.10.60 8 81 3.0E-5 T 11-10-2018 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Gene3D G3DSA:1.10.10.10 213 288 3.9E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Pfam PF03979 Sigma-70 factor, region 1.1 17 85 1.3E-15 T 11-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 PRINTS PR00046 Major sigma-70 factor signature 188 196 2.8E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 PRINTS PR00046 Major sigma-70 factor signature 348 359 2.8E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 PRINTS PR00046 Major sigma-70 factor signature 164 177 2.8E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 PRINTS PR00046 Major sigma-70 factor signature 333 348 2.8E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 PRINTS PR00046 Major sigma-70 factor signature 312 324 2.8E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Gene3D G3DSA:1.10.10.10 289 373 2.7E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Gene3D G3DSA:1.10.220.120 15 74 3.2E-9 T 11-10-2018 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 SUPERFAMILY SSF88946 101 210 4.97E-53 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 333 359 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 138 361 1.0E-39 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 SUPERFAMILY SSF88659 270 371 5.42E-30 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 SUPERFAMILY SSF88659 213 286 1.29E-23 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 9 373 34.038 T 11-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Pfam PF04539 Sigma-70 region 3 219 295 4.1E-33 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Pfam PF00140 Sigma-70 factor, region 1.2 102 135 2.2E-16 T 11-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Pfam PF04542 Sigma-70 region 2 140 209 3.3E-22 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 137 372 1.0E-125 T 11-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Gene3D G3DSA:1.10.601.10 100 135 7.1E-11 T 11-10-2018 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Gene3D G3DSA:1.10.601.10 136 212 3.5E-51 T 11-10-2018 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 164 177 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11430 aafe65fd8d8fbf7f6d6c5f25702f17e7 373 Pfam PF04545 Sigma-70, region 4 308 361 5.1E-20 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_16190 530d678453a1c9473c6df47c54969235 436 Gene3D G3DSA:3.40.640.10 57 294 2.9E-32 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_16190 530d678453a1c9473c6df47c54969235 436 Pfam PF00266 Aminotransferase class-V 63 418 3.3E-28 T 11-10-2018 IPR000192 Aminotransferase class V domain UP12_16190 530d678453a1c9473c6df47c54969235 436 SUPERFAMILY SSF53383 17 420 4.41E-45 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_16190 530d678453a1c9473c6df47c54969235 436 Gene3D G3DSA:3.90.1150.10 300 429 1.5E-18 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_07175 dd219bd05bca20dca76a02157a4aff82 309 Pfam PF04960 Glutaminase 23 309 3.1E-109 T 11-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 UP12_07175 dd219bd05bca20dca76a02157a4aff82 309 TIGRFAM TIGR03814 Gln_ase: glutaminase A 9 309 2.8E-122 T 11-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 UP12_07175 dd219bd05bca20dca76a02157a4aff82 309 Hamap MF_00313 Glutaminase [glsA]. 5 309 44.094 T 11-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 UP12_07175 dd219bd05bca20dca76a02157a4aff82 309 Gene3D G3DSA:3.40.710.10 4 309 3.8E-110 T 11-10-2018 UP12_07175 dd219bd05bca20dca76a02157a4aff82 309 SUPERFAMILY SSF56601 8 309 9.73E-111 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 SUPERFAMILY SSF55021 2 77 8.77E-19 T 11-10-2018 UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 SUPERFAMILY SSF55021 80 160 1.5E-25 T 11-10-2018 UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 Gene3D G3DSA:3.30.70.1150 84 165 4.1E-29 T 11-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 1.5E-64 T 11-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 Pfam PF10369 Small subunit of acetolactate synthase 85 157 5.6E-28 T 11-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 1.0E-31 T 11-10-2018 UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 Gene3D G3DSA:3.30.70.260 1 80 4.9E-29 T 11-10-2018 UP12_12425 c33cf7a37f212e8b5b87c90129a11f30 172 Pfam PF01842 ACT domain 4 68 7.2E-16 T 11-10-2018 IPR002912 ACT domain UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 Gene3D G3DSA:3.40.250.10 85 186 2.7E-28 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 SMART SM00450 91 186 2.4E-21 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 Pfam PF01206 Sulfurtransferase TusA 7 75 1.3E-19 T 11-10-2018 IPR001455 TusA-like domain UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 Gene3D G3DSA:3.30.110.40 2 76 3.1E-26 T 11-10-2018 IPR036868 TusA-like domain superfamily UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 SUPERFAMILY SSF52821 87 183 5.89E-31 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 11-10-2018 IPR001455 TusA-like domain UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 Pfam PF00581 Rhodanese-like domain 93 181 7.5E-16 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 SUPERFAMILY SSF64307 2 75 1.07E-21 T 11-10-2018 IPR036868 TusA-like domain superfamily UP12_01295 5785acb9baa20c978deb6e86a146f66f 186 ProSitePatterns PS00380 Rhodanese signature 1. 116 127 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 UP12_12000 d163456f4499ffbbdd049482e11121b8 269 SMART SM00062 47 269 3.1E-76 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_12000 d163456f4499ffbbdd049482e11121b8 269 Gene3D G3DSA:3.40.190.10 135 232 1.9E-81 T 11-10-2018 UP12_12000 d163456f4499ffbbdd049482e11121b8 269 Gene3D G3DSA:3.40.190.10 48 266 1.9E-81 T 11-10-2018 UP12_12000 d163456f4499ffbbdd049482e11121b8 269 SUPERFAMILY SSF53850 4 268 6.44E-68 T 11-10-2018 UP12_12000 d163456f4499ffbbdd049482e11121b8 269 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 71 84 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site UP12_12000 d163456f4499ffbbdd049482e11121b8 269 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 268 4.2E-57 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_12000 d163456f4499ffbbdd049482e11121b8 269 SMART SM00079 47 269 7.5E-6 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 UP12_18680 51f8cbafffafa26635c8b60f6cd8651d 393 SUPERFAMILY SSF103473 10 390 1.44E-47 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_18680 51f8cbafffafa26635c8b60f6cd8651d 393 Gene3D G3DSA:1.20.1250.20 211 390 1.4E-15 T 11-10-2018 UP12_18680 51f8cbafffafa26635c8b60f6cd8651d 393 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_18680 51f8cbafffafa26635c8b60f6cd8651d 393 Pfam PF07690 Major Facilitator Superfamily 13 303 3.5E-28 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_18680 51f8cbafffafa26635c8b60f6cd8651d 393 Gene3D G3DSA:1.20.1250.20 8 194 6.9E-27 T 11-10-2018 UP12_01305 603426ee2ff4684bc4584dfa890750c1 76 SUPERFAMILY SSF64307 3 75 4.06E-25 T 11-10-2018 IPR036868 TusA-like domain superfamily UP12_01305 603426ee2ff4684bc4584dfa890750c1 76 Pfam PF01206 Sulfurtransferase TusA 7 74 9.9E-24 T 11-10-2018 IPR001455 TusA-like domain UP12_01305 603426ee2ff4684bc4584dfa890750c1 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 11-10-2018 IPR001455 TusA-like domain UP12_01305 603426ee2ff4684bc4584dfa890750c1 76 Gene3D G3DSA:3.30.110.40 1 76 4.1E-29 T 11-10-2018 IPR036868 TusA-like domain superfamily UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 PIRSF PIRSF000722 1 394 1.5E-155 T 11-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 SUPERFAMILY SSF53067 157 393 1.19E-94 T 11-10-2018 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 Gene3D G3DSA:3.30.420.40 195 394 1.5E-83 T 11-10-2018 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 Hamap MF_00020 Acetate kinase [ackA]. 1 394 198.147 T 11-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 SUPERFAMILY SSF53067 1 194 2.78E-72 T 11-10-2018 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 PRINTS PR00471 Acetate kinase family signature 299 312 1.7E-47 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 PRINTS PR00471 Acetate kinase family signature 202 223 1.7E-47 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 PRINTS PR00471 Acetate kinase family signature 4 15 1.7E-47 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 PRINTS PR00471 Acetate kinase family signature 321 337 1.7E-47 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 PRINTS PR00471 Acetate kinase family signature 172 185 1.7E-47 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 PRINTS PR00471 Acetate kinase family signature 375 387 1.7E-47 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 Gene3D G3DSA:3.30.420.40 2 194 1.1E-75 T 11-10-2018 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 TIGRFAM TIGR00016 ackA: acetate kinase 2 393 4.5E-180 T 11-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_13195 a781bd309c4b8ca08b7f642a26d9c203 394 Pfam PF00871 Acetokinase family 3 388 1.4E-174 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 UP12_11945 e6ba6d50bf764c5531f1447b01b870aa 221 SUPERFAMILY SSF53335 26 218 3.87E-41 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_11945 e6ba6d50bf764c5531f1447b01b870aa 221 Gene3D G3DSA:3.40.50.150 2 220 3.1E-63 T 11-10-2018 UP12_11945 e6ba6d50bf764c5531f1447b01b870aa 221 Pfam PF01596 O-methyltransferase 43 216 1.9E-29 T 11-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 UP12_11770 bbb05b83597c3efacf57b922fbcec5ba 241 Pfam PF01323 DSBA-like thioredoxin domain 2 204 7.8E-49 T 11-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 UP12_11770 bbb05b83597c3efacf57b922fbcec5ba 241 Gene3D G3DSA:3.40.30.10 1 208 6.8E-80 T 11-10-2018 UP12_11770 bbb05b83597c3efacf57b922fbcec5ba 241 SUPERFAMILY SSF52833 1 211 1.72E-48 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_16420 c116516158291fb4c2a6c1db63f93549 471 SMART SM00304 189 242 5.6E-8 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 3.4E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 SUPERFAMILY SSF47384 226 306 1.8E-18 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 SUPERFAMILY SSF158472 191 239 4.71E-7 T 11-10-2018 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 SMART SM00387 351 463 1.0E-35 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_16420 c116516158291fb4c2a6c1db63f93549 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 305 1.1E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 462 2.7E-25 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_16420 c116516158291fb4c2a6c1db63f93549 471 Gene3D G3DSA:3.30.565.10 311 467 2.2E-43 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_16420 c116516158291fb4c2a6c1db63f93549 471 SMART SM00388 243 306 3.8E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_16420 c116516158291fb4c2a6c1db63f93549 471 SUPERFAMILY SSF55874 296 462 2.36E-47 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_16420 c116516158291fb4c2a6c1db63f93549 471 Gene3D G3DSA:1.10.287.130 187 302 2.6E-30 T 11-10-2018 UP12_13730 387f7c767f037a6794a1a1ab54759276 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 3.9E-5 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_13730 387f7c767f037a6794a1a1ab54759276 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 6.9E-8 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_13730 387f7c767f037a6794a1a1ab54759276 171 Gene3D G3DSA:2.160.10.10 1 171 3.1E-71 T 11-10-2018 UP12_13730 387f7c767f037a6794a1a1ab54759276 171 SUPERFAMILY SSF51161 3 168 2.77E-49 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 SUPERFAMILY SSF55604 6 81 6.28E-20 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 Gene3D G3DSA:3.30.1360.60 1 77 1.7E-27 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 618 2.3E-231 T 11-10-2018 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 SUPERFAMILY SSF51261 468 617 1.6E-51 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 Pfam PF00367 phosphotransferase system, EIIB 9 41 6.1E-11 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 Gene3D G3DSA:2.70.70.10 462 618 1.5E-54 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 473 596 1.5E-48 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 475 594 1.9E-42 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 Pfam PF02378 Phosphotransferase system, EIIC 110 388 9.4E-30 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_01380 82d58e01bfed8a4b71d6c517e509e7a1 619 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 536 548 - T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 UP12_01755 1991c3cdf305a2febf48767f449040be 127 ProDom PD015812 YOPD YWLA YOAG 47 122 3.0E-6 T 11-10-2018 IPR031374 Uncharacterised protein family UPF0715 UP12_01755 1991c3cdf305a2febf48767f449040be 127 Pfam PF17094 Uncharacterised protein family (UPF0715) 10 122 1.2E-40 T 11-10-2018 IPR031374 Uncharacterised protein family UPF0715 UP12_18505 39622e00ae57df8e325b52c8685009f4 299 Pfam PF03466 LysR substrate binding domain 89 275 1.1E-43 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_18505 39622e00ae57df8e325b52c8685009f4 299 Gene3D G3DSA:1.10.10.10 1 91 9.7E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18505 39622e00ae57df8e325b52c8685009f4 299 Gene3D G3DSA:3.40.190.290 92 291 5.4E-43 T 11-10-2018 UP12_18505 39622e00ae57df8e325b52c8685009f4 299 SUPERFAMILY SSF53850 90 294 1.48E-38 T 11-10-2018 UP12_18505 39622e00ae57df8e325b52c8685009f4 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18505 39622e00ae57df8e325b52c8685009f4 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18505 39622e00ae57df8e325b52c8685009f4 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18505 39622e00ae57df8e325b52c8685009f4 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.3E-19 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18505 39622e00ae57df8e325b52c8685009f4 299 SUPERFAMILY SSF46785 3 111 7.79E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_05215 704a9f1947f10aee416d30f1cc8c3357 194 Gene3D G3DSA:3.40.50.1240 1 193 9.3E-55 T 11-10-2018 IPR029033 Histidine phosphatase superfamily UP12_05215 704a9f1947f10aee416d30f1cc8c3357 194 SMART SM00855 3 146 3.4E-25 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UP12_05215 704a9f1947f10aee416d30f1cc8c3357 194 PIRSF PIRSF000709 2 109 3.7E-7 T 11-10-2018 UP12_05215 704a9f1947f10aee416d30f1cc8c3357 194 PIRSF PIRSF000709 129 160 33.0 T 11-10-2018 UP12_05215 704a9f1947f10aee416d30f1cc8c3357 194 SUPERFAMILY SSF53254 2 190 1.7E-58 T 11-10-2018 IPR029033 Histidine phosphatase superfamily UP12_05215 704a9f1947f10aee416d30f1cc8c3357 194 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 11-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 UP12_05215 704a9f1947f10aee416d30f1cc8c3357 194 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 183 2.9E-53 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UP12_04775 f474a65c92bdd5db925055ecc5e0b803 530 Gene3D G3DSA:1.10.10.2840 394 525 8.7E-12 T 11-10-2018 UP12_04775 f474a65c92bdd5db925055ecc5e0b803 530 Pfam PF13556 PucR C-terminal helix-turn-helix domain 463 520 2.0E-13 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_04775 f474a65c92bdd5db925055ecc5e0b803 530 Pfam PF07905 Purine catabolism regulatory protein-like family 11 129 5.0E-36 T 11-10-2018 IPR012914 Purine catabolism PurC-like domain UP12_13645 cc5d9ab8f5491ad8e254074dae2cd57c 250 SUPERFAMILY SSF51735 1 246 1.44E-27 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13645 cc5d9ab8f5491ad8e254074dae2cd57c 250 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 178 2.8E-14 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UP12_13645 cc5d9ab8f5491ad8e254074dae2cd57c 250 Gene3D G3DSA:3.40.50.720 1 238 5.9E-32 T 11-10-2018 UP12_15820 37cf6a9ba6f0aa7f5da0e356853ee374 96 SUPERFAMILY SSF89447 2 49 2.22E-13 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily UP12_15820 37cf6a9ba6f0aa7f5da0e356853ee374 96 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 50 3.6E-6 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_15820 37cf6a9ba6f0aa7f5da0e356853ee374 96 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 10 49 2.2E-9 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_15820 37cf6a9ba6f0aa7f5da0e356853ee374 96 SMART SM00966 8 51 7.0E-6 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_15820 37cf6a9ba6f0aa7f5da0e356853ee374 96 Gene3D G3DSA:2.10.260.10 1 54 3.4E-20 T 11-10-2018 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 SUPERFAMILY SSF47384 229 313 8.63E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 SMART SM00388 245 313 7.3E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 SMART SM00387 359 467 1.1E-26 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 Gene3D G3DSA:1.10.287.130 185 307 3.4E-17 T 11-10-2018 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 Gene3D G3DSA:3.30.565.10 308 467 1.0E-32 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 SUPERFAMILY SSF55874 303 466 4.71E-33 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 2.1E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 2.1E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 2.1E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 2.1E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 466 1.5E-19 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_08970 ac485a8debc8a745ba25f596ef84c4dc 467 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 309 9.0E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_03980 91100cee606b52c3f5e5bcbe66f5708f 172 Pfam PF01965 DJ-1/PfpI family 3 168 1.9E-54 T 11-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UP12_03980 91100cee606b52c3f5e5bcbe66f5708f 172 SUPERFAMILY SSF52317 1 170 6.02E-46 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_03980 91100cee606b52c3f5e5bcbe66f5708f 172 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 171 2.3E-58 T 11-10-2018 IPR006286 Deglycase PfpI UP12_03980 91100cee606b52c3f5e5bcbe66f5708f 172 Gene3D G3DSA:3.40.50.880 1 171 2.6E-53 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_05890 fc17f858673ebe4f00ac7112dc3b13f3 45 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 19 43 2.3E-13 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_05890 fc17f858673ebe4f00ac7112dc3b13f3 45 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 21 44 2.8E-11 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_03720 6f5ad8aac9debee9bcf574888d17d1cd 323 Gene3D G3DSA:3.40.50.720 3 183 1.8E-51 T 11-10-2018 UP12_03720 6f5ad8aac9debee9bcf574888d17d1cd 323 Gene3D G3DSA:3.90.25.10 184 323 1.2E-40 T 11-10-2018 UP12_03720 6f5ad8aac9debee9bcf574888d17d1cd 323 Pfam PF16363 GDP-mannose 4,6 dehydratase 11 313 1.8E-57 T 11-10-2018 IPR016040 NAD(P)-binding domain UP12_03720 6f5ad8aac9debee9bcf574888d17d1cd 323 SUPERFAMILY SSF51735 3 321 1.27E-86 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 SMART SM00878 346 453 6.4E-51 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 326 3.9E-81 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Gene3D G3DSA:3.10.600.10 464 506 2.8E-8 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Gene3D G3DSA:3.10.600.10 507 1061 1.6E-289 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Gene3D G3DSA:1.10.10.2790 944 979 1.6E-289 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 SUPERFAMILY SSF56059 88 333 5.66E-72 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Gene3D G3DSA:1.10.472.90 819 943 1.6E-289 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Gene3D G3DSA:3.20.20.70 514 818 1.6E-289 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Gene3D G3DSA:2.40.50.100 1069 1146 8.9E-23 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Gene3D G3DSA:3.30.470.130 1 461 2.6E-196 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 SUPERFAMILY SSF89000 834 1011 1.18E-59 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 SUPERFAMILY SSF51569 526 837 3.66E-80 T 11-10-2018 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 8 1145 0.0 T 11-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Pfam PF02436 Conserved carboxylase domain 829 1029 9.9E-81 T 11-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 SUPERFAMILY SSF51246 341 460 2.15E-37 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 SUPERFAMILY SSF52440 4 117 2.09E-44 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Pfam PF00364 Biotin-requiring enzyme 1079 1145 3.5E-15 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 114 4.5E-42 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 PIRSF PIRSF001594 1 1147 0.0 T 11-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Pfam PF00682 HMGL-like 534 806 1.4E-27 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 346 453 1.1E-31 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_07190 3c54e38ab9f93e0f2d0c4c5972a0e327 1148 SUPERFAMILY SSF51230 1070 1145 4.97E-20 T 11-10-2018 IPR011053 Single hybrid motif UP12_16480 05169e9dc71ccc5c9a872b81419976ab 282 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 14 216 3.2E-62 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_16480 05169e9dc71ccc5c9a872b81419976ab 282 Gene3D G3DSA:3.30.70.120 193 269 4.8E-24 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_16480 05169e9dc71ccc5c9a872b81419976ab 282 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 222 276 2.5E-19 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 UP12_16480 05169e9dc71ccc5c9a872b81419976ab 282 PIRSF PIRSF006483 1 282 4.0E-83 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 62 156 0.002 T 11-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 15 381 2.2E-176 T 11-10-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 SMART SM00835 50 194 4.3E-15 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 SMART SM00835 230 371 9.7E-32 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 Pfam PF00190 Cupin 231 366 1.0E-23 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 Pfam PF00190 Cupin 62 189 1.8E-18 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 SUPERFAMILY SSF51182 17 380 3.6E-105 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 Gene3D G3DSA:2.60.120.10 58 231 2.6E-166 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_15270 1fa7c9ba97ea3b63a5751d3fe94a2e1e 385 Gene3D G3DSA:2.60.120.10 9 375 2.6E-166 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_10420 f499086065782b5466abcc1c2e09e437 244 SMART SM00363 2 63 6.3E-16 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_10420 f499086065782b5466abcc1c2e09e437 244 Gene3D G3DSA:3.10.290.10 1 63 4.5E-22 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_10420 f499086065782b5466abcc1c2e09e437 244 Gene3D G3DSA:3.30.70.580 64 222 8.0E-56 T 11-10-2018 UP12_10420 f499086065782b5466abcc1c2e09e437 244 Gene3D G3DSA:3.30.70.1560 123 215 8.0E-56 T 11-10-2018 UP12_10420 f499086065782b5466abcc1c2e09e437 244 Pfam PF01479 S4 domain 2 48 6.3E-15 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_10420 f499086065782b5466abcc1c2e09e437 244 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 9.6E-51 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 UP12_10420 f499086065782b5466abcc1c2e09e437 244 SUPERFAMILY SSF55120 46 237 5.04E-44 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_10420 f499086065782b5466abcc1c2e09e437 244 SUPERFAMILY SSF55174 2 67 1.06E-16 T 11-10-2018 UP12_10420 f499086065782b5466abcc1c2e09e437 244 Pfam PF00849 RNA pseudouridylate synthase 62 196 8.1E-24 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_10420 f499086065782b5466abcc1c2e09e437 244 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 UP12_04970 7a5ce9f17026ea3949517d955733cc78 291 Pfam PF13556 PucR C-terminal helix-turn-helix domain 231 284 1.6E-16 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_04970 7a5ce9f17026ea3949517d955733cc78 291 SUPERFAMILY SSF46689 233 264 3.14E-5 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_04970 7a5ce9f17026ea3949517d955733cc78 291 Gene3D G3DSA:1.10.10.2840 175 289 2.2E-13 T 11-10-2018 UP12_01795 be48c349bd271289d4708a53813fe9d3 126 Gene3D G3DSA:1.25.40.10 2 126 3.9E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 5 124 1.2E-15 T 11-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 Gene3D G3DSA:3.30.390.10 6 115 3.1E-118 T 11-10-2018 IPR029017 Enolase-like, N-terminal UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 Pfam PF13378 Enolase C-terminal domain-like 143 353 2.1E-54 T 11-10-2018 IPR029065 Enolase C-terminal domain-like UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 SUPERFAMILY SSF54826 1 125 9.2E-32 T 11-10-2018 UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 Gene3D G3DSA:3.20.20.120 116 351 3.1E-118 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 188 219 - T 11-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 SUPERFAMILY SSF51604 112 353 3.14E-71 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily UP12_06305 07574af8c6b9271519f97c91d09a1e5e 359 SMART SM00922 141 238 3.1E-30 T 11-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal UP12_06510 ce74cacc308f4dde14ee0951c6541e78 64 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 3.4E-22 T 11-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 UP12_06510 ce74cacc308f4dde14ee0951c6541e78 64 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 UP12_06510 ce74cacc308f4dde14ee0951c6541e78 64 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 UP12_06510 ce74cacc308f4dde14ee0951c6541e78 64 Gene3D G3DSA:1.10.8.910 5 64 1.8E-29 T 11-10-2018 IPR038300 SASP, alpha/beta-type superfamily UP12_13815 43356e16c2256af409a0f4699b5cd4d4 134 Pfam PF05105 Bacteriophage holin family 17 128 1.4E-23 T 11-10-2018 IPR006480 Bacteriophage holin family UP12_13815 43356e16c2256af409a0f4699b5cd4d4 134 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 11 132 3.3E-25 T 11-10-2018 IPR006480 Bacteriophage holin family UP12_09055 d574be801dde61f6c90120ca9452c6b9 506 Pfam PF07690 Major Facilitator Superfamily 18 409 9.8E-59 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_09055 d574be801dde61f6c90120ca9452c6b9 506 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 486 4.3E-86 T 11-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UP12_09055 d574be801dde61f6c90120ca9452c6b9 506 Gene3D G3DSA:1.20.1720.10 14 221 6.9E-56 T 11-10-2018 UP12_09055 d574be801dde61f6c90120ca9452c6b9 506 SUPERFAMILY SSF103473 8 497 5.89E-79 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01690 264b987058455e1918ce5214499b2541 293 SUPERFAMILY SSF53850 188 293 5.58E-26 T 11-10-2018 UP12_01690 264b987058455e1918ce5214499b2541 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 172 1.3E-39 T 11-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 UP12_01690 264b987058455e1918ce5214499b2541 293 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 191 293 3.4E-22 T 11-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 UP12_01690 264b987058455e1918ce5214499b2541 293 SUPERFAMILY SSF53850 33 186 1.19E-49 T 11-10-2018 UP12_01690 264b987058455e1918ce5214499b2541 293 Gene3D G3DSA:3.10.105.10 116 272 3.8E-117 T 11-10-2018 UP12_01690 264b987058455e1918ce5214499b2541 293 Gene3D G3DSA:3.40.190.230 34 291 3.8E-117 T 11-10-2018 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 532 1.1E-283 T 11-10-2018 IPR014251 Sporulation protease LonB UP12_12380 77471c8ce943b86cca740ec2921588f1 553 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 1.2E-33 T 11-10-2018 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 1.2E-33 T 11-10-2018 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 1.2E-33 T 11-10-2018 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 1.2E-33 T 11-10-2018 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 1.2E-33 T 11-10-2018 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 342 534 1.6E-34 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 SUPERFAMILY SSF52540 55 328 1.1E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12380 77471c8ce943b86cca740ec2921588f1 553 Gene3D G3DSA:3.30.230.10 342 551 9.4E-53 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_12380 77471c8ce943b86cca740ec2921588f1 553 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 442 450 - T 11-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 Gene3D G3DSA:3.40.50.300 52 263 3.8E-32 T 11-10-2018 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 265 1.0E-19 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_12380 77471c8ce943b86cca740ec2921588f1 553 SUPERFAMILY SSF54211 352 532 1.33E-41 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_12380 77471c8ce943b86cca740ec2921588f1 553 SMART SM00382 89 267 2.2E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00750 f594bb53651e8e9edbb891052df54cbc 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.573 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00750 f594bb53651e8e9edbb891052df54cbc 113 SUPERFAMILY SSF54843 1 112 2.22E-44 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00750 f594bb53651e8e9edbb891052df54cbc 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 3.1E-37 T 11-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 UP12_00750 f594bb53651e8e9edbb891052df54cbc 113 Gene3D G3DSA:3.90.470.10 1 113 4.3E-51 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 UP12_00750 f594bb53651e8e9edbb891052df54cbc 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 4.4E-54 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00750 f594bb53651e8e9edbb891052df54cbc 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 11-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 450 1.2E-23 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Gene3D G3DSA:3.40.120.10 34 190 1.5E-47 T 11-10-2018 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 SUPERFAMILY SSF55957 446 576 4.58E-15 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Gene3D G3DSA:3.40.120.10 326 452 2.9E-36 T 11-10-2018 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 SUPERFAMILY SSF53738 208 319 4.71E-21 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Gene3D G3DSA:3.40.120.10 209 325 4.4E-23 T 11-10-2018 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 SUPERFAMILY SSF53738 30 235 1.29E-46 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 SUPERFAMILY SSF53738 304 455 2.86E-32 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 508 550 6.1E-9 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Gene3D G3DSA:3.30.310.50 477 573 9.8E-10 T 11-10-2018 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 210 318 4.1E-24 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 43 182 2.8E-42 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 6.5E-6 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_04805 95bc58811a181415d9ab125a2ab16533 581 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 6.5E-6 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 35 406 4.0E-170 T 11-10-2018 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 SUPERFAMILY SSF56266 19 402 6.8E-136 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 Gene3D G3DSA:3.30.2330.10 193 277 1.6E-32 T 11-10-2018 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 12 406 1.2E-170 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 Gene3D G3DSA:3.10.20.340 278 406 5.6E-47 T 11-10-2018 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 Gene3D G3DSA:3.60.70.12 5 192 4.1E-67 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 Pfam PF01960 ArgJ family 24 406 9.2E-148 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UP12_05570 ea6f3078abdb069ffa5a54ff6719b7f8 406 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 406 142.192 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 UP12_15995 f477dd7f64c31f116966163823d09314 540 Gene3D G3DSA:3.10.105.10 283 507 2.9E-141 T 11-10-2018 UP12_15995 f477dd7f64c31f116966163823d09314 540 TIGRFAM TIGR02294 nickel_nikA: nickel ABC transporter, nickel/metallophore periplasmic binding protein 39 538 1.4E-208 T 11-10-2018 IPR011980 Nickel ABC transporter, substrate-binding protein NikA GO:0015675|GO:0016151|GO:0020037 UP12_15995 f477dd7f64c31f116966163823d09314 540 Gene3D G3DSA:3.40.190.10 67 282 2.9E-141 T 11-10-2018 UP12_15995 f477dd7f64c31f116966163823d09314 540 PIRSF PIRSF002741 6 535 2.8E-100 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UP12_15995 f477dd7f64c31f116966163823d09314 540 SUPERFAMILY SSF53850 44 527 2.17E-120 T 11-10-2018 UP12_15995 f477dd7f64c31f116966163823d09314 540 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 454 3.7E-93 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain UP12_00290 02ef768737921e140d53a6f183ae1072 61 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 13 22 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 UP12_00290 02ef768737921e140d53a6f183ae1072 61 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 10 54 7.7E-8 T 11-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 UP12_00290 02ef768737921e140d53a6f183ae1072 61 Gene3D G3DSA:1.10.8.910 7 61 9.4E-6 T 11-10-2018 IPR038300 SASP, alpha/beta-type superfamily UP12_09215 2e4f7c510725095951aa340313968c38 76 Pfam PF12728 Helix-turn-helix domain 2 46 1.1E-7 T 11-10-2018 UP12_09215 2e4f7c510725095951aa340313968c38 76 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 2 50 1.0E-13 T 11-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 Pfam PF13620 Carboxypeptidase regulatory-like domain 644 711 4.5E-8 T 11-10-2018 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 Gene3D G3DSA:2.60.40.1120 570 638 2.7E-9 T 11-10-2018 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 Gene3D G3DSA:3.40.50.200 181 517 1.7E-79 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 PRINTS PR00723 Subtilisin serine protease family (S8) signature 216 235 6.2E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 PRINTS PR00723 Subtilisin serine protease family (S8) signature 268 281 6.2E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 PRINTS PR00723 Subtilisin serine protease family (S8) signature 447 463 6.2E-14 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 SUPERFAMILY SSF49464 576 639 3.92E-7 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 448 458 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 Gene3D G3DSA:2.60.40.10 976 1057 2.0E-15 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 SUPERFAMILY SSF52743 197 515 3.53E-70 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 Pfam PF00082 Subtilase family 216 502 1.0E-51 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 Pfam PF05922 Peptidase inhibitor I9 68 178 2.3E-7 T 11-10-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 Gene3D G3DSA:2.60.40.1120 645 725 1.6E-10 T 11-10-2018 UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 272 282 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_07420 63e5699d867899c5cff43f87a3fa3ac4 1167 SUPERFAMILY SSF49464 644 740 1.12E-11 T 11-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily UP12_00455 743e8449c8cde0b178efcf77404949b6 282 SUPERFAMILY SSF56752 1 270 9.03E-64 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 UP12_00455 743e8449c8cde0b178efcf77404949b6 282 Pfam PF01063 Amino-transferase class IV 29 253 9.2E-48 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 UP12_00455 743e8449c8cde0b178efcf77404949b6 282 ProSitePatterns PS00770 Aminotransferases class-IV signature. 179 208 - T 11-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 UP12_00455 743e8449c8cde0b178efcf77404949b6 282 Gene3D G3DSA:3.30.470.10 1 124 5.5E-29 T 11-10-2018 UP12_00455 743e8449c8cde0b178efcf77404949b6 282 Gene3D G3DSA:3.20.10.10 125 277 1.7E-39 T 11-10-2018 UP12_12435 0b30013e1fc7743623137370c10a7257 304 SUPERFAMILY SSF56752 6 290 3.27E-92 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 UP12_12435 0b30013e1fc7743623137370c10a7257 304 Pfam PF01063 Amino-transferase class IV 35 261 1.5E-55 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 UP12_12435 0b30013e1fc7743623137370c10a7257 304 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 10 290 2.2E-99 T 11-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 UP12_12435 0b30013e1fc7743623137370c10a7257 304 Gene3D G3DSA:3.20.10.10 130 294 1.9E-55 T 11-10-2018 UP12_12435 0b30013e1fc7743623137370c10a7257 304 ProSitePatterns PS00770 Aminotransferases class-IV signature. 188 217 - T 11-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 UP12_12435 0b30013e1fc7743623137370c10a7257 304 Gene3D G3DSA:3.30.470.10 4 129 2.8E-47 T 11-10-2018 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Gene3D G3DSA:1.10.10.2480 1 71 1.4E-15 T 11-10-2018 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Pfam PF11987 Translation-initiation factor 2 493 597 1.8E-38 T 11-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 705 17.579 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 SUPERFAMILY SSF52540 199 379 3.53E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 48 4.4E-13 T 11-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 131 180 2.2E-16 T 11-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Pfam PF00009 Elongation factor Tu GTP binding domain 212 367 1.0E-35 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 123 705 1.1E-284 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Gene3D G3DSA:3.40.50.300 204 378 8.4E-75 T 11-10-2018 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Gene3D G3DSA:3.40.50.10050 501 608 2.4E-40 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily UP12_08130 fcad81a521905deb26e2ca11776f0508 706 SUPERFAMILY SSF52156 485 614 6.67E-41 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily UP12_08130 fcad81a521905deb26e2ca11776f0508 706 ProSitePatterns PS01176 Initiation factor 2 signature. 658 680 - T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Gene3D G3DSA:2.40.30.10 609 706 2.6E-32 T 11-10-2018 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 210 366 9.3E-43 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_08130 fcad81a521905deb26e2ca11776f0508 706 SUPERFAMILY SSF50447 608 705 1.64E-32 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_08130 fcad81a521905deb26e2ca11776f0508 706 SUPERFAMILY SSF50447 379 462 7.54E-26 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily UP12_08130 fcad81a521905deb26e2ca11776f0508 706 Gene3D G3DSA:2.40.30.10 379 496 5.1E-42 T 11-10-2018 UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 SUPERFAMILY SSF53901 213 409 1.24E-65 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 SMART SM00825 Beta-ketoacyl synthase 4 410 7.2E-15 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 PIRSF PIRSF000447 1 410 1.5E-164 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 5.4E-33 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 Gene3D G3DSA:3.40.47.10 255 398 5.0E-47 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 SUPERFAMILY SSF53901 1 248 1.71E-74 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 407 1.1E-171 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 245 2.1E-60 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UP12_01265 b831fd7d6a8ad7166cab7b36b30abfb3 410 Gene3D G3DSA:3.40.47.10 1 253 1.0E-89 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_06465 6b831e18737398bec1e18c1775867eba 122 Gene3D G3DSA:2.60.120.10 1 104 5.2E-34 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_06465 6b831e18737398bec1e18c1775867eba 122 SUPERFAMILY SSF51182 3 113 1.16E-26 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_06465 6b831e18737398bec1e18c1775867eba 122 Pfam PF07883 Cupin domain 36 94 2.4E-12 T 11-10-2018 IPR013096 Cupin 2, conserved barrel UP12_06410 97a3375497adf8f834a0272ea633731c 156 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 101 1.4E-26 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain UP12_06410 97a3375497adf8f834a0272ea633731c 156 Gene3D G3DSA:3.40.140.10 1 156 1.8E-68 T 11-10-2018 UP12_06410 97a3375497adf8f834a0272ea633731c 156 SUPERFAMILY SSF53927 2 139 3.9E-47 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_06410 97a3375497adf8f834a0272ea633731c 156 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 257 5.6E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 226 241 5.6E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 Gene3D G3DSA:3.40.50.1980 258 363 4.5E-8 T 11-10-2018 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 Pfam PF12833 Helix-turn-helix domain 180 258 1.9E-20 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 Gene3D G3DSA:1.10.10.60 157 211 1.7E-14 T 11-10-2018 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 SMART SM00342 174 257 4.9E-30 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 SUPERFAMILY SSF46689 159 208 2.6E-8 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 Gene3D G3DSA:3.40.50.1980 364 526 6.8E-26 T 11-10-2018 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 SUPERFAMILY SSF53807 260 509 3.92E-29 T 11-10-2018 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 SUPERFAMILY SSF46689 210 261 2.11E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 211 253 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 Gene3D G3DSA:1.10.10.2730 212 257 7.9E-18 T 11-10-2018 UP12_04200 54da8061bb3ae1c29c465c187707321a 534 Pfam PF01497 Periplasmic binding protein 320 499 1.5E-11 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 3.7E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 3.7E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 3.7E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 3.7E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 3.7E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 3.7E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 319 1.5E-163 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 Gene3D G3DSA:3.90.226.10 2 316 1.9E-121 T 11-10-2018 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 49.066 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 SUPERFAMILY SSF52096 6 313 9.57E-101 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_13115 327082dd19c2c6d2f62652478a8b23c8 325 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 2.5E-65 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 Pfam PF00701 Dihydrodipicolinate synthetase family 7 304 2.9E-45 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 SUPERFAMILY SSF51569 3 309 2.51E-70 T 11-10-2018 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 3.4E-8 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 3.4E-8 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 3.4E-8 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 Gene3D G3DSA:3.20.20.70 1 307 1.6E-76 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 SMART SM01130 6 307 9.7E-74 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_01855 c5ee092b83679e99f9bc9f7779765ae6 315 PIRSF PIRSF001365 2 313 1.9E-62 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_12680 cbc1890d99d12596981855cc351d92b0 441 Pfam PF13175 AAA ATPase domain 260 374 2.4E-16 T 11-10-2018 UP12_12680 cbc1890d99d12596981855cc351d92b0 441 Pfam PF13175 AAA ATPase domain 11 173 2.3E-12 T 11-10-2018 UP12_12680 cbc1890d99d12596981855cc351d92b0 441 Pfam PF12476 Protein of unknown function (DUF3696) 386 424 3.4E-5 T 11-10-2018 IPR022532 Domain of unknown function DUF3696, C-terminal UP12_12680 cbc1890d99d12596981855cc351d92b0 441 PIRSF PIRSF034888 207 439 9.5E-33 T 11-10-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 UP12_12680 cbc1890d99d12596981855cc351d92b0 441 PIRSF PIRSF034888 97 170 170.0 T 11-10-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 UP12_12680 cbc1890d99d12596981855cc351d92b0 441 PIRSF PIRSF034888 10 151 5.4E-12 T 11-10-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 UP12_12680 cbc1890d99d12596981855cc351d92b0 441 SUPERFAMILY SSF52540 11 378 1.41E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08205 1992ac19417461f2b13b5afec293afc9 288 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 287 4.1E-117 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 1.0E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 1.0E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 1.0E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 1.0E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 Pfam PF00701 Dihydrodipicolinate synthetase family 3 287 2.4E-115 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 SMART SM01130 2 286 1.6E-129 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 11-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 11-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 SUPERFAMILY SSF51569 3 286 6.8E-97 T 11-10-2018 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 2 288 63.02 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 PIRSF PIRSF001365 1 288 7.4E-94 T 11-10-2018 IPR002220 DapA-like GO:0016829 UP12_08205 1992ac19417461f2b13b5afec293afc9 288 Gene3D G3DSA:3.20.20.70 1 288 2.6E-110 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 Hamap MF_01987 Ribokinase [rbsK]. 2 291 24.78 T 11-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 Pfam PF00294 pfkB family carbohydrate kinase 1 284 5.4E-75 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 4 289 1.9E-104 T 11-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 SUPERFAMILY SSF53613 1 290 2.03E-78 T 11-10-2018 IPR029056 Ribokinase-like UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 Gene3D G3DSA:3.40.1190.20 1 292 1.3E-93 T 11-10-2018 IPR029056 Ribokinase-like UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 PRINTS PR00990 Ribokinase signature 33 52 7.4E-34 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 PRINTS PR00990 Ribokinase signature 207 218 7.4E-34 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 PRINTS PR00990 Ribokinase signature 6 27 7.4E-34 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 PRINTS PR00990 Ribokinase signature 172 187 7.4E-34 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UP12_16890 164ba19007eb367dc0b4100ad6f7ef44 292 PRINTS PR00990 Ribokinase signature 104 117 7.4E-34 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 UP12_05510 087d24234d57eeb989831879dde3765b 549 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 476 1.2E-30 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_05510 087d24234d57eeb989831879dde3765b 549 Gene3D G3DSA:1.10.287.950 245 547 3.1E-57 T 11-10-2018 UP12_05510 087d24234d57eeb989831879dde3765b 549 Pfam PF00672 HAMP domain 190 238 1.6E-11 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_05510 087d24234d57eeb989831879dde3765b 549 SMART SM00304 190 243 1.7E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_05510 087d24234d57eeb989831879dde3765b 549 Gene3D G3DSA:1.20.1480.50 149 244 3.7E-17 T 11-10-2018 UP12_05510 087d24234d57eeb989831879dde3765b 549 SUPERFAMILY SSF58104 215 547 1.7E-62 T 11-10-2018 UP12_05510 087d24234d57eeb989831879dde3765b 549 SMART SM00283 272 547 2.7E-41 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_10050 3dbe04ff7efdd9cd42d9a996cebb54fd 288 SUPERFAMILY SSF52374 1 280 2.01E-103 T 11-10-2018 UP12_10050 3dbe04ff7efdd9cd42d9a996cebb54fd 288 Pfam PF02569 Pantoate-beta-alanine ligase 3 276 5.3E-101 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UP12_10050 3dbe04ff7efdd9cd42d9a996cebb54fd 288 Gene3D G3DSA:3.30.1300.10 178 276 2.1E-32 T 11-10-2018 UP12_10050 3dbe04ff7efdd9cd42d9a996cebb54fd 288 Hamap MF_00158 Pantothenate synthetase [panC]. 2 278 38.788 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UP12_10050 3dbe04ff7efdd9cd42d9a996cebb54fd 288 Gene3D G3DSA:3.40.50.620 1 177 1.3E-72 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_10050 3dbe04ff7efdd9cd42d9a996cebb54fd 288 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 85 7.6E-10 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_10050 3dbe04ff7efdd9cd42d9a996cebb54fd 288 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 277 8.2E-115 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 UP12_19075 7c8e048372281d83401527f9ca9ec17b 323 Gene3D G3DSA:3.10.180.10 13 307 9.6E-124 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_19075 7c8e048372281d83401527f9ca9ec17b 323 Gene3D G3DSA:3.10.180.10 73 216 9.6E-124 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_19075 7c8e048372281d83401527f9ca9ec17b 323 SUPERFAMILY SSF54593 11 284 6.36E-50 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_19075 7c8e048372281d83401527f9ca9ec17b 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 102 3.9E-16 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_19075 7c8e048372281d83401527f9ca9ec17b 323 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 162 272 2.9E-15 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_14475 31fae96a6d5018891472a19f8ac38360 65 SUPERFAMILY SSF47413 6 64 4.74E-9 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_14475 31fae96a6d5018891472a19f8ac38360 65 Gene3D G3DSA:1.10.260.40 5 65 3.5E-8 T 11-10-2018 UP12_11090 a791572957f096cfce2369723a62b0bc 144 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 44.786 T 11-10-2018 IPR022897 HTH-type transcription regulator MntR UP12_11090 a791572957f096cfce2369723a62b0bc 144 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 124 1.4E-19 T 11-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 UP12_11090 a791572957f096cfce2369723a62b0bc 144 SMART SM00529 24 122 3.9E-44 T 11-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 UP12_11090 a791572957f096cfce2369723a62b0bc 144 Gene3D G3DSA:1.10.10.10 1 73 9.7E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11090 a791572957f096cfce2369723a62b0bc 144 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 8.3E-27 T 11-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 UP12_11090 a791572957f096cfce2369723a62b0bc 144 Gene3D G3DSA:1.10.60.10 74 142 3.3E-34 T 11-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 UP12_11090 a791572957f096cfce2369723a62b0bc 144 SUPERFAMILY SSF46785 3 62 2.97E-17 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_11090 a791572957f096cfce2369723a62b0bc 144 SUPERFAMILY SSF47979 63 127 2.16E-19 T 11-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 SUPERFAMILY SSF53927 4 145 3.41E-44 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 359 1.5E-68 T 11-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 Gene3D G3DSA:3.40.430.10 137 362 3.9E-79 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 Pfam PF01872 RibD C-terminal domain 148 355 1.5E-57 T 11-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 SUPERFAMILY SSF53597 146 360 1.31E-62 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 Gene3D G3DSA:3.40.140.10 2 136 1.1E-43 T 11-10-2018 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 100 3.4E-20 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 PIRSF PIRSF006769 2 362 8.3E-135 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 UP12_18130 2c734aad574bdebfd2636c9aa7a1872e 363 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 356 7.2E-123 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 UP12_08975 a5d9360f12e1cca3a10bcbf45f41ca35 235 SMART SM00448 6 117 2.7E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_08975 a5d9360f12e1cca3a10bcbf45f41ca35 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 9.0E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_08975 a5d9360f12e1cca3a10bcbf45f41ca35 235 Pfam PF00072 Response regulator receiver domain 8 117 4.3E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_08975 a5d9360f12e1cca3a10bcbf45f41ca35 235 Gene3D G3DSA:3.40.50.2300 2 130 2.3E-34 T 11-10-2018 UP12_08975 a5d9360f12e1cca3a10bcbf45f41ca35 235 SMART SM00862 154 230 7.8E-26 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_08975 a5d9360f12e1cca3a10bcbf45f41ca35 235 SUPERFAMILY SSF52172 7 188 2.25E-37 T 11-10-2018 IPR011006 CheY-like superfamily UP12_08975 a5d9360f12e1cca3a10bcbf45f41ca35 235 Gene3D G3DSA:1.10.10.10 131 235 3.2E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_19010 6164e0792f11e1f258cabf6682bb4965 321 Pfam PF01497 Periplasmic binding protein 63 289 3.6E-27 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_19010 6164e0792f11e1f258cabf6682bb4965 321 SUPERFAMILY SSF53807 47 311 9.42E-56 T 11-10-2018 UP12_19010 6164e0792f11e1f258cabf6682bb4965 321 Gene3D G3DSA:3.40.50.1980 40 164 9.3E-29 T 11-10-2018 UP12_19010 6164e0792f11e1f258cabf6682bb4965 321 Gene3D G3DSA:3.40.50.1980 165 321 6.8E-43 T 11-10-2018 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 SUPERFAMILY SSF160544 251 358 4.71E-43 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 TIGRFAM TIGR01404 FlhB_rel_III: type III secretion protein, YscU/HrpY family 14 355 2.0E-98 T 11-10-2018 IPR006307 Type III exporter system, secretion apparatus protein BsaZ GO:0009306|GO:0016021 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 Pfam PF01312 FlhB HrpN YscU SpaS Family 14 354 1.4E-133 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 279 294 1.9E-43 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 235 252 1.9E-43 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 309 330 1.9E-43 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 17 39 1.9E-43 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 215 233 1.9E-43 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 Gene3D G3DSA:3.40.1690.10 225 362 7.8E-59 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal UP12_07985 8f9d0c851ed0fffadd3afc9342f48a62 362 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 15 360 4.2E-136 T 11-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 UP12_08770 548cfa2282e234a72315083322e3a3cd 140 Pfam PF03061 Thioesterase superfamily 18 102 3.6E-14 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UP12_08770 548cfa2282e234a72315083322e3a3cd 140 Gene3D G3DSA:3.10.129.10 3 128 2.1E-36 T 11-10-2018 UP12_08770 548cfa2282e234a72315083322e3a3cd 140 PIRSF PIRSF003230 2 136 1.2E-31 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 UP12_08770 548cfa2282e234a72315083322e3a3cd 140 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 2.2E-35 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 UP12_08770 548cfa2282e234a72315083322e3a3cd 140 SUPERFAMILY SSF54637 6 131 2.75E-39 T 11-10-2018 IPR029069 HotDog domain superfamily UP12_01455 f79ef02d222cdb03667c6e422d9c3adc 312 Pfam PF02574 Homocysteine S-methyltransferase 14 306 1.7E-81 T 11-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 UP12_01455 f79ef02d222cdb03667c6e422d9c3adc 312 SUPERFAMILY SSF82282 6 309 4.32E-88 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UP12_01455 f79ef02d222cdb03667c6e422d9c3adc 312 PIRSF PIRSF037505 269 310 14.0 T 11-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 UP12_01455 f79ef02d222cdb03667c6e422d9c3adc 312 PIRSF PIRSF037505 2 136 7.8E-7 T 11-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 UP12_01455 f79ef02d222cdb03667c6e422d9c3adc 312 Gene3D G3DSA:3.20.20.330 1 308 1.7E-112 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 UP12_15220 254b0a6ba7ebe758f1b3c8e21021e714 91 Gene3D G3DSA:3.50.4.20 1 91 1.2E-43 T 11-10-2018 IPR038141 YutD-like superfamily UP12_15220 254b0a6ba7ebe758f1b3c8e21021e714 91 PIRSF PIRSF012565 1 91 5.1E-50 T 11-10-2018 IPR009370 Protein of unknown function DUF1027 UP12_15220 254b0a6ba7ebe758f1b3c8e21021e714 91 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 1.0E-38 T 11-10-2018 IPR009370 Protein of unknown function DUF1027 UP12_11710 06f066c998cd33cd16a03f72a4b1ed37 141 PRINTS PR00502 NUDIX hydrolase family signature 28 42 1.2E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_11710 06f066c998cd33cd16a03f72a4b1ed37 141 PRINTS PR00502 NUDIX hydrolase family signature 42 57 1.2E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_11710 06f066c998cd33cd16a03f72a4b1ed37 141 ProSitePatterns PS00893 Nudix box signature. 33 54 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UP12_11710 06f066c998cd33cd16a03f72a4b1ed37 141 Gene3D G3DSA:3.90.79.10 2 130 8.2E-29 T 11-10-2018 UP12_11710 06f066c998cd33cd16a03f72a4b1ed37 141 SUPERFAMILY SSF55811 3 115 1.9E-26 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UP12_11710 06f066c998cd33cd16a03f72a4b1ed37 141 Pfam PF00293 NUDIX domain 4 117 1.3E-18 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UP12_12870 d292b191417131a4e2f8a801e223349c 194 SUPERFAMILY SSF48498 78 191 5.24E-32 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_12870 d292b191417131a4e2f8a801e223349c 194 Gene3D G3DSA:1.10.357.10 50 194 1.0E-41 T 11-10-2018 UP12_12870 d292b191417131a4e2f8a801e223349c 194 Pfam PF08359 YsiA-like protein, C-terminal region 58 190 3.5E-61 T 11-10-2018 IPR013570 Transcription regulator YsiA, C-terminal UP12_12870 d292b191417131a4e2f8a801e223349c 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 6.2E-17 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_12870 d292b191417131a4e2f8a801e223349c 194 Gene3D G3DSA:1.10.10.60 1 49 2.0E-23 T 11-10-2018 UP12_12870 d292b191417131a4e2f8a801e223349c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.4E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_12870 d292b191417131a4e2f8a801e223349c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.4E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_12870 d292b191417131a4e2f8a801e223349c 194 SUPERFAMILY SSF46689 6 82 1.5E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_17040 247cf78e372b3d117745295133a2daf1 226 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 9 219 2.5E-60 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_17040 247cf78e372b3d117745295133a2daf1 226 SMART SM00062 5 220 9.9E-55 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_17040 247cf78e372b3d117745295133a2daf1 226 Gene3D G3DSA:3.40.190.10 88 182 1.9E-59 T 11-10-2018 UP12_17040 247cf78e372b3d117745295133a2daf1 226 Gene3D G3DSA:3.40.190.10 3 217 1.9E-59 T 11-10-2018 UP12_17040 247cf78e372b3d117745295133a2daf1 226 SUPERFAMILY SSF53850 3 222 8.96E-55 T 11-10-2018 UP12_16750 cff4f3ceaa0fe3728fb714850cede8fc 316 Gene3D G3DSA:2.60.120.10 228 316 1.2E-30 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_16750 cff4f3ceaa0fe3728fb714850cede8fc 316 Gene3D G3DSA:2.60.120.10 1 227 2.0E-97 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_16750 cff4f3ceaa0fe3728fb714850cede8fc 316 SUPERFAMILY SSF51182 4 315 2.19E-109 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_16750 cff4f3ceaa0fe3728fb714850cede8fc 316 PIRSF PIRSF036894 3 316 1.2E-133 T 11-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 UP12_16750 cff4f3ceaa0fe3728fb714850cede8fc 316 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 6 315 2.7E-93 T 11-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UP12_16750 cff4f3ceaa0fe3728fb714850cede8fc 316 Pfam PF01238 Phosphomannose isomerase type I 8 315 5.3E-66 T 11-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 Pfam PF00367 phosphotransferase system, EIIB 8 41 4.8E-14 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 SUPERFAMILY SSF55604 6 79 2.62E-20 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 157 443 2.8E-93 T 11-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 Pfam PF02378 Phosphotransferase system, EIIC 114 398 7.9E-55 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 455 7.1E-189 T 11-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 Gene3D G3DSA:3.30.1360.60 1 77 5.2E-27 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_17755 4f09d470b9df460c105784f98fd954bf 462 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 115 9.3E-18 T 11-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 9.2E-19 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 305 9.1E-51 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 SUPERFAMILY SSF57716 11 46 1.71E-11 T 11-10-2018 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 SMART SM00994 10 49 8.0E-24 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 SMART SM01086 311 407 8.4E-35 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 Gene3D G3DSA:1.10.8.60 310 417 6.8E-38 T 11-10-2018 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 SUPERFAMILY SSF52540 59 392 1.26E-79 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 SMART SM00382 108 259 9.2E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 Pfam PF06689 ClpX C4-type zinc finger 12 48 2.6E-20 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 Gene3D G3DSA:3.30.50.30 3 50 1.0E-21 T 11-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 Gene3D G3DSA:3.40.50.300 53 309 5.2E-107 T 11-10-2018 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 1 405 1.5E-216 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UP12_12385 9efbd70842d3463120a7dccb52146ccb 421 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 409 53.684 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 UP12_19040 7651508d9a1ab6a879f1d8102b2f68f6 309 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 309 47.445 T 11-10-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_19040 7651508d9a1ab6a879f1d8102b2f68f6 309 Gene3D G3DSA:3.10.310.20 190 309 5.3E-39 T 11-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_19040 7651508d9a1ab6a879f1d8102b2f68f6 309 Pfam PF02833 DHHA2 domain 183 306 1.9E-21 T 11-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_19040 7651508d9a1ab6a879f1d8102b2f68f6 309 Pfam PF01368 DHH family 3 146 1.5E-31 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_19040 7651508d9a1ab6a879f1d8102b2f68f6 309 SMART SM01131 181 307 1.7E-55 T 11-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_19040 7651508d9a1ab6a879f1d8102b2f68f6 309 SUPERFAMILY SSF64182 2 307 3.4E-85 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily UP12_19040 7651508d9a1ab6a879f1d8102b2f68f6 309 Gene3D G3DSA:3.90.1640.10 1 188 1.7E-81 T 11-10-2018 UP12_06120 994cdff221679096eff584d5400cc54e 296 Pfam PF00700 Bacterial flagellin C-terminal helical region 210 295 4.8E-33 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_06120 994cdff221679096eff584d5400cc54e 296 SUPERFAMILY SSF64518 1 296 9.15E-92 T 11-10-2018 UP12_06120 994cdff221679096eff584d5400cc54e 296 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 146 4.3E-40 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_06120 994cdff221679096eff584d5400cc54e 296 Gene3D G3DSA:1.10.8.410 248 296 3.1E-29 T 11-10-2018 UP12_06120 994cdff221679096eff584d5400cc54e 296 Gene3D G3DSA:1.20.1330.10 53 247 2.7E-58 T 11-10-2018 UP12_06120 994cdff221679096eff584d5400cc54e 296 PRINTS PR00207 Flagellin signature 35 52 7.7E-18 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06120 994cdff221679096eff584d5400cc54e 296 PRINTS PR00207 Flagellin signature 110 133 7.7E-18 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06120 994cdff221679096eff584d5400cc54e 296 PRINTS PR00207 Flagellin signature 74 93 7.7E-18 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_07725 035fef8bbeea458f690f9376b6d113a1 300 Pfam PF03313 Serine dehydratase alpha chain 15 274 3.4E-77 T 11-10-2018 IPR005130 Serine dehydratase-like, alpha subunit UP12_07725 035fef8bbeea458f690f9376b6d113a1 300 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 299 6.7E-150 T 11-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 UP12_08855 b2791baf8e0ac78129190815cae4bd62 214 Pfam PF13460 NAD(P)H-binding 7 200 1.2E-32 T 11-10-2018 IPR016040 NAD(P)-binding domain UP12_08855 b2791baf8e0ac78129190815cae4bd62 214 SUPERFAMILY SSF51735 1 213 1.33E-27 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08855 b2791baf8e0ac78129190815cae4bd62 214 Gene3D G3DSA:3.40.50.720 1 209 4.2E-35 T 11-10-2018 UP12_18215 06ca8316f603629955702163b996a1e2 155 SMART SM00530 13 67 9.7E-4 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_18215 06ca8316f603629955702163b996a1e2 155 Pfam PF01381 Helix-turn-helix 15 45 2.3E-5 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_18215 06ca8316f603629955702163b996a1e2 155 Gene3D G3DSA:1.10.260.40 3 68 4.4E-7 T 11-10-2018 UP12_18215 06ca8316f603629955702163b996a1e2 155 SUPERFAMILY SSF47413 7 61 1.05E-8 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 Pfam PF01026 TatD related DNase 3 252 5.7E-91 T 11-10-2018 IPR001130 TatD family GO:0016788 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 PIRSF PIRSF005902 1 255 9.8E-94 T 11-10-2018 IPR001130 TatD family GO:0016788 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 11-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 11-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 Gene3D G3DSA:3.20.20.140 1 255 5.8E-114 T 11-10-2018 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 124 134 - T 11-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 2.8E-104 T 11-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 UP12_00260 9741664bd264d7f1ef8d887170dd54b8 255 SUPERFAMILY SSF51556 2 254 5.68E-98 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_10730 3b6318056ad5c9f1e46d47255c869d12 537 PIRSF PIRSF010386 1 537 6.7E-211 T 11-10-2018 IPR012166 Uncharacterised protein family RocB UP12_10730 3b6318056ad5c9f1e46d47255c869d12 537 SUPERFAMILY SSF53187 7 516 1.78E-24 T 11-10-2018 UP12_10730 3b6318056ad5c9f1e46d47255c869d12 537 Pfam PF01546 Peptidase family M20/M25/M40 126 323 1.1E-9 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_10730 3b6318056ad5c9f1e46d47255c869d12 537 Gene3D G3DSA:3.40.630.10 5 234 2.6E-33 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 Gene3D G3DSA:3.50.50.60 148 268 1.2E-116 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 Gene3D G3DSA:3.50.50.60 3 326 1.2E-116 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 458 1.3E-170 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 340 448 5.3E-34 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 Gene3D G3DSA:3.30.390.30 339 459 1.1E-40 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 SUPERFAMILY SSF51905 3 367 8.64E-61 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 336 357 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 4.1E-66 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PIRSF PIRSF000350 1 458 1.2E-93 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 9.1E-39 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 9.1E-39 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 9.1E-39 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 9.1E-39 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 9.1E-39 T 11-10-2018 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 321 4.2E-73 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_02615 35e7536e6785359b7ca6da2aae7dde04 459 SUPERFAMILY SSF55424 337 458 2.23E-37 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_19660 982210a1dfbc73b3e0beb3f9616fb46d 218 Gene3D G3DSA:1.10.3290.10 1 217 4.0E-64 T 11-10-2018 IPR036597 Fido-like domain superfamily UP12_19660 982210a1dfbc73b3e0beb3f9616fb46d 218 Pfam PF02661 Fic/DOC family 54 151 9.7E-18 T 11-10-2018 IPR003812 Fido domain UP12_19660 982210a1dfbc73b3e0beb3f9616fb46d 218 SUPERFAMILY SSF140931 43 196 3.79E-32 T 11-10-2018 IPR036597 Fido-like domain superfamily UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 Gene3D G3DSA:3.40.980.10 4 173 5.2E-52 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 6 415 2.3E-177 T 11-10-2018 IPR008135 Competence-induced protein CinA UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 268 411 6.4E-46 T 11-10-2018 IPR008136 CinA, C-terminal UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 Pfam PF02464 Competence-damaged protein 261 412 4.1E-51 T 11-10-2018 IPR008136 CinA, C-terminal UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 PIRSF PIRSF006728 4 416 9.8E-165 T 11-10-2018 IPR008135 Competence-induced protein CinA UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 6 170 6.5E-38 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 SUPERFAMILY SSF53218 6 210 2.75E-41 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 Pfam PF00994 Probable molybdopterin binding domain 8 172 8.4E-36 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 SMART SM00852 8 175 1.3E-41 T 11-10-2018 IPR001453 MoaB/Mog domain UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 SUPERFAMILY SSF142433 254 414 1.96E-49 T 11-10-2018 IPR036653 CinA-like, C-terminal UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 416 170.335 T 11-10-2018 IPR008135 Competence-induced protein CinA UP12_08290 5245992d9a7dc8201fb68395d18dae3c 416 Gene3D G3DSA:3.90.950.20 256 414 2.4E-51 T 11-10-2018 IPR036653 CinA-like, C-terminal UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 SMART SM00388 357 424 1.8E-23 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Gene3D G3DSA:3.30.565.10 426 578 8.8E-52 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Gene3D G3DSA:3.30.450.20 33 157 2.0E-9 T 11-10-2018 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Pfam PF00512 His Kinase A (phospho-acceptor) domain 357 423 3.5E-20 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Gene3D G3DSA:1.10.287.130 353 425 6.2E-27 T 11-10-2018 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 579 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 560 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 239 357 3.5E-7 T 11-10-2018 IPR000014 PAS domain UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 579 6.4E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Pfam PF16736 Single Cache-like 34 146 3.2E-36 T 11-10-2018 IPR031967 PhoR, single Cache-like domain UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Pfam PF00989 PAS fold 242 348 1.1E-10 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 SUPERFAMILY SSF55785 235 349 4.19E-9 T 11-10-2018 IPR035965 PAS domain superfamily UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 Gene3D G3DSA:3.30.450.20 227 352 1.2E-15 T 11-10-2018 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 SUPERFAMILY SSF55874 413 579 1.27E-51 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 SUPERFAMILY SSF47384 343 425 1.35E-21 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_13065 d313cb459ffc3fb9d01d14c958ea6f02 581 SMART SM00387 470 581 5.5E-41 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_00790 0f330000afbd93b594e093b87fb96ee7 61 Gene3D G3DSA:4.10.830.10 1 61 5.3E-30 T 11-10-2018 UP12_00790 0f330000afbd93b594e093b87fb96ee7 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 11-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00790 0f330000afbd93b594e093b87fb96ee7 61 SUPERFAMILY SSF57716 3 61 4.35E-22 T 11-10-2018 UP12_00790 0f330000afbd93b594e093b87fb96ee7 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.723 T 11-10-2018 IPR023053 Ribosomal protein S14, type Z UP12_00790 0f330000afbd93b594e093b87fb96ee7 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 1.9E-24 T 11-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 Gene3D G3DSA:3.90.1170.20 12 272 3.4E-101 T 11-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 274 6.2E-100 T 11-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 105 4.0E-23 T 11-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 108 272 2.4E-63 T 11-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 Gene3D G3DSA:3.20.20.70 122 264 3.4E-101 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 SUPERFAMILY SSF54675 4 107 5.65E-26 T 11-10-2018 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 SUPERFAMILY SSF51690 108 274 1.26E-58 T 11-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 UP12_12200 cc2e7ef6d6aa78a35aec01df4108e8de 287 PIRSF PIRSF006250 1 277 1.4E-100 T 11-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 UP12_08955 4d3b37a47540ccbb86de0c9c1b209bf8 308 SUPERFAMILY SSF53474 83 308 2.54E-36 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_08955 4d3b37a47540ccbb86de0c9c1b209bf8 308 Gene3D G3DSA:3.40.50.1820 18 308 2.9E-69 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_08955 4d3b37a47540ccbb86de0c9c1b209bf8 308 Pfam PF07859 alpha/beta hydrolase fold 87 288 4.2E-38 T 11-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 1 494 36.499 T 11-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 180 485 5.6E-119 T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 SUPERFAMILY SSF52949 9 178 1.24E-34 T 11-10-2018 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 16 142 3.6E-26 T 11-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 PRINTS PR00481 Cytosol aminopeptidase signature 256 273 3.3E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 PRINTS PR00481 Cytosol aminopeptidase signature 278 299 3.3E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 PRINTS PR00481 Cytosol aminopeptidase signature 315 336 3.3E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 PRINTS PR00481 Cytosol aminopeptidase signature 337 357 3.3E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 PRINTS PR00481 Cytosol aminopeptidase signature 365 380 3.3E-50 T 11-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 341 348 - T 11-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 SUPERFAMILY SSF53187 176 490 4.08E-114 T 11-10-2018 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 Gene3D G3DSA:3.40.220.10 1 152 4.3E-39 T 11-10-2018 UP12_15100 5c9a9780929aa94400b8b1e501e5c67b 496 Gene3D G3DSA:3.40.630.10 166 492 4.0E-130 T 11-10-2018 UP12_05925 2ff14926839cdae3fbce5be37e4bc022 372 Gene3D G3DSA:3.40.640.10 4 246 1.2E-87 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_05925 2ff14926839cdae3fbce5be37e4bc022 372 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 362 3.6E-138 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_05925 2ff14926839cdae3fbce5be37e4bc022 372 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_05925 2ff14926839cdae3fbce5be37e4bc022 372 PIRSF PIRSF001434 1 366 6.6E-122 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_05925 2ff14926839cdae3fbce5be37e4bc022 372 Gene3D G3DSA:3.90.1150.10 247 278 8.2E-9 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_05925 2ff14926839cdae3fbce5be37e4bc022 372 SUPERFAMILY SSF53383 20 365 8.74E-104 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_05925 2ff14926839cdae3fbce5be37e4bc022 372 Gene3D G3DSA:3.90.1150.10 279 372 2.5E-25 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:2.40.50.150 791 930 2.2E-61 T 11-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:2.40.270.10 981 1047 4.7E-25 T 11-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:2.40.270.10 752 790 4.2E-6 T 11-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Pfam PF04563 RNA polymerase beta subunit 28 454 4.9E-30 T 11-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:3.90.1800.10 1057 1110 1.1E-10 T 11-10-2018 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 370 410 5.3E-7 T 11-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 289 2.8E-28 T 11-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:3.90.1100.10 20 153 6.3E-53 T 11-10-2018 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:3.90.1100.10 605 671 5.2E-19 T 11-10-2018 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1145 4.7E-27 T 11-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:3.90.1110.10 154 271 8.7E-9 T 11-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 11-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:3.90.1100.10 389 592 7.0E-74 T 11-10-2018 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Pfam PF04565 RNA polymerase Rpb2, domain 3 469 537 3.5E-30 T 11-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Gene3D G3DSA:2.40.50.100 672 751 1.2E-27 T 11-10-2018 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 SUPERFAMILY SSF64484 13 1156 0.0 T 11-10-2018 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Pfam PF00562 RNA polymerase Rpb2, domain 6 678 1069 3.6E-165 T 11-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Pfam PF10385 RNA polymerase beta subunit external 1 domain 547 614 4.7E-25 T 11-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.591 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_00680 52051ce5223de0cb8ba797344e601d9f 1193 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 896 0.0 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 UP12_07240 5d6df90659206cf40176c40e82299e0c 140 Pfam PF00571 CBS domain 61 110 8.4E-13 T 11-10-2018 IPR000644 CBS domain UP12_07240 5d6df90659206cf40176c40e82299e0c 140 Pfam PF00571 CBS domain 1 47 1.1E-11 T 11-10-2018 IPR000644 CBS domain UP12_07240 5d6df90659206cf40176c40e82299e0c 140 SUPERFAMILY SSF54631 1 110 1.77E-30 T 11-10-2018 UP12_07240 5d6df90659206cf40176c40e82299e0c 140 SMART SM00116 68 115 5.2E-7 T 11-10-2018 IPR000644 CBS domain UP12_07240 5d6df90659206cf40176c40e82299e0c 140 SMART SM00116 4 51 5.5E-9 T 11-10-2018 IPR000644 CBS domain UP12_07240 5d6df90659206cf40176c40e82299e0c 140 Gene3D G3DSA:3.10.580.10 1 140 3.5E-36 T 11-10-2018 UP12_04255 2acfaf1beec6d736e4ada6bbd08cee42 856 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 538 829 1.8E-95 T 11-10-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal UP12_04255 2acfaf1beec6d736e4ada6bbd08cee42 856 SUPERFAMILY SSF55729 647 828 6.81E-15 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_04255 2acfaf1beec6d736e4ada6bbd08cee42 856 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 14 293 9.5E-12 T 11-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD UP12_05625 56c2535b5743fca5494ebd27e6e2febd 320 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 28 318 6.4E-70 T 11-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 UP12_05625 56c2535b5743fca5494ebd27e6e2febd 320 Gene3D G3DSA:3.40.50.2300 41 285 5.7E-72 T 11-10-2018 UP12_05625 56c2535b5743fca5494ebd27e6e2febd 320 SUPERFAMILY SSF53822 27 233 9.62E-23 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_05625 56c2535b5743fca5494ebd27e6e2febd 320 Gene3D G3DSA:3.40.50.2300 134 297 5.7E-72 T 11-10-2018 UP12_17250 7d5366602a9d62fe6f167fc12421e340 351 SUPERFAMILY SSF55821 21 217 2.29E-65 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily UP12_17250 7d5366602a9d62fe6f167fc12421e340 351 Pfam PF03481 Putative GTP-binding controlling metal-binding 207 343 1.1E-28 T 11-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain UP12_17250 7d5366602a9d62fe6f167fc12421e340 351 Gene3D G3DSA:3.40.50.11030 224 351 2.4E-40 T 11-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily UP12_17250 7d5366602a9d62fe6f167fc12421e340 351 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 22 215 5.4E-67 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 UP12_17250 7d5366602a9d62fe6f167fc12421e340 351 PIRSF PIRSF004930 3 349 2.9E-130 T 11-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 UP12_17250 7d5366602a9d62fe6f167fc12421e340 351 Pfam PF01300 Telomere recombination 29 205 2.1E-58 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 UP12_17250 7d5366602a9d62fe6f167fc12421e340 351 Gene3D G3DSA:3.90.870.10 11 221 1.6E-81 T 11-10-2018 UP12_00440 184a9c57f2dca4e60d731c0e411b4d63 307 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 304 4.2E-137 T 11-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 UP12_00440 184a9c57f2dca4e60d731c0e411b4d63 307 TIGRFAM TIGR01139 cysK: cysteine synthase A 10 304 4.1E-146 T 11-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 UP12_00440 184a9c57f2dca4e60d731c0e411b4d63 307 Gene3D G3DSA:3.40.50.1100 7 300 1.1E-124 T 11-10-2018 UP12_00440 184a9c57f2dca4e60d731c0e411b4d63 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 1.4E-71 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UP12_00440 184a9c57f2dca4e60d731c0e411b4d63 307 SUPERFAMILY SSF53686 3 304 1.06E-104 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UP12_00440 184a9c57f2dca4e60d731c0e411b4d63 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 UP12_00440 184a9c57f2dca4e60d731c0e411b4d63 307 Gene3D G3DSA:3.40.50.1100 46 144 1.1E-124 T 11-10-2018 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 Gene3D G3DSA:1.10.220.30 107 198 2.2E-34 T 11-10-2018 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 38 64 1.3E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 199 224 1.3E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 252 272 1.3E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 118 141 1.3E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 230 250 1.3E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 9 25 1.3E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 276 302 1.3E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 1 338 5.9E-161 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 SUPERFAMILY SSF48029 118 329 7.59E-71 T 11-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 Pfam PF01706 FliG C-terminal domain 222 328 3.4E-43 T 11-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 PIRSF PIRSF003161 3 338 2.5E-126 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 Pfam PF14842 FliG N-terminal domain 9 111 4.1E-36 T 11-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 Gene3D G3DSA:1.10.220.30 199 338 8.9E-51 T 11-10-2018 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 Gene3D G3DSA:1.10.220.30 2 86 1.3E-18 T 11-10-2018 UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 Pfam PF14841 FliG middle domain 119 193 3.5E-31 T 11-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain UP12_07900 7917ee4faed88c6837aa352bc69a1b2c 338 SUPERFAMILY SSF48029 10 104 4.71E-20 T 11-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 PRINTS PR00207 Flagellin signature 35 52 1.2E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 PRINTS PR00207 Flagellin signature 74 93 1.2E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 PRINTS PR00207 Flagellin signature 110 133 1.2E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 Gene3D G3DSA:1.10.8.410 246 299 2.9E-29 T 11-10-2018 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 Gene3D G3DSA:1.20.58.1830 3 31 1.2E-58 T 11-10-2018 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 SUPERFAMILY SSF64518 1 299 7.06E-89 T 11-10-2018 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 Gene3D G3DSA:2.170.280.10 188 197 1.2E-58 T 11-10-2018 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 Pfam PF00700 Bacterial flagellin C-terminal helical region 213 298 6.3E-33 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 Gene3D G3DSA:1.20.1330.10 43 187 1.2E-58 T 11-10-2018 UP12_06110 5776e82a5549e0d32d1318a25fb33c78 299 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 146 3.9E-40 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00385 P450 superfamily signature 346 357 2.6E-6 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00385 P450 superfamily signature 271 282 2.6E-6 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00385 P450 superfamily signature 236 253 2.6E-6 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00385 P450 superfamily signature 337 346 2.6E-6 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 SUPERFAMILY SSF48264 24 397 2.23E-96 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 Gene3D G3DSA:1.10.630.10 2 397 3.8E-133 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 Pfam PF00067 Cytochrome P450 49 395 3.8E-37 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 11-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 316 331 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 337 346 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 271 282 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 346 357 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 144 159 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 288 315 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 127 143 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 190 212 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_09345 8ed1977fde03797c5ab7c12caf8b4d7f 398 PRINTS PR00359 B-class P450 signature 81 92 1.1E-54 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 Gene3D G3DSA:1.10.10.10 2 68 2.2E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 Hamap MF_00015 LexA repressor [lexA]. 3 205 34.418 T 11-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 SUPERFAMILY SSF46785 3 70 1.88E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 131 142 3.8E-9 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 120 130 3.8E-9 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 160 172 3.8E-9 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 Pfam PF00717 Peptidase S24-like 123 189 4.0E-17 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 TIGRFAM TIGR00498 lexA: repressor LexA 1 206 1.3E-84 T 11-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 Gene3D G3DSA:2.10.109.10 88 205 2.1E-42 T 11-10-2018 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 Pfam PF01726 LexA DNA binding domain 1 65 1.0E-28 T 11-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 UP12_08680 47c945b23d9f512b599f12d9d62bc864 206 SUPERFAMILY SSF51306 82 203 4.88E-36 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Hamap MF_01973 Lon protease [lon]. 9 770 72.227 T 11-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Gene3D G3DSA:2.30.130.40 1 114 5.1E-31 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 SUPERFAMILY SSF52540 308 586 1.8E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 SUPERFAMILY SSF88697 8 198 1.09E-44 T 11-10-2018 IPR015947 PUA-like superfamily UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Gene3D G3DSA:1.10.8.60 490 582 6.2E-31 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 198 9.0E-40 T 11-10-2018 IPR003111 Lon, substrate-binding domain UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 2.5E-98 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 674 682 - T 11-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 2.3E-55 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 2.3E-55 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 2.3E-55 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 2.3E-55 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 2.3E-55 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Gene3D G3DSA:1.20.58.1480 119 243 4.8E-44 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Gene3D G3DSA:3.30.230.10 591 774 1.4E-86 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 SUPERFAMILY SSF54211 593 768 4.55E-57 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 SMART SM00464 8 200 1.1E-74 T 11-10-2018 IPR003111 Lon, substrate-binding domain UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 487 6.5E-23 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 TIGRFAM TIGR00763 lon: endopeptidase La 10 769 2.9E-304 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 Gene3D G3DSA:3.40.50.300 312 489 1.3E-68 T 11-10-2018 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 PIRSF PIRSF001174 1 773 0.0 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 UP12_12375 46c9339f0f5f15ee8b2ab68ddadff350 774 SMART SM00382 346 494 7.6E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_02895 44431eb220d0cd1052a5d496eaff3b09 478 Gene3D G3DSA:3.40.50.1820 38 202 4.2E-7 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02895 44431eb220d0cd1052a5d496eaff3b09 478 SUPERFAMILY SSF53474 20 269 7.8E-15 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_09495 10fa4155b6497252f88d8365768b5a64 112 Gene3D G3DSA:2.30.29.50 5 112 3.7E-28 T 11-10-2018 IPR037063 Bacterial Pleckstrin homology domain superfamily UP12_09495 10fa4155b6497252f88d8365768b5a64 112 Pfam PF08000 Bacterial PH domain 8 110 1.2E-23 T 11-10-2018 IPR012544 Bacterial Pleckstrin homology domain UP12_09495 10fa4155b6497252f88d8365768b5a64 112 SUPERFAMILY SSF50729 9 111 2.64E-27 T 11-10-2018 UP12_05910 53671800a940948f411aa3f7c15ad959 144 SUPERFAMILY SSF55729 3 143 1.65E-34 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_05910 53671800a940948f411aa3f7c15ad959 144 Gene3D G3DSA:3.40.630.30 3 144 2.2E-38 T 11-10-2018 UP12_05910 53671800a940948f411aa3f7c15ad959 144 Pfam PF13673 Acetyltransferase (GNAT) domain 13 142 1.7E-21 T 11-10-2018 IPR000182 GNAT domain UP12_11645 1c961f65d0ee7522279b8e6104bd75a9 187 Pfam PF01966 HD domain 18 130 2.3E-16 T 11-10-2018 IPR006674 HD domain UP12_11645 1c961f65d0ee7522279b8e6104bd75a9 187 TIGRFAM TIGR00277 HDIG: HDIG domain 16 93 3.1E-7 T 11-10-2018 IPR006675 HDIG domain UP12_11645 1c961f65d0ee7522279b8e6104bd75a9 187 SMART SM00471 14 141 6.2E-12 T 11-10-2018 IPR003607 HD/PDEase domain UP12_11645 1c961f65d0ee7522279b8e6104bd75a9 187 SUPERFAMILY SSF109604 3 185 5.42E-38 T 11-10-2018 UP12_11645 1c961f65d0ee7522279b8e6104bd75a9 187 Gene3D G3DSA:1.10.3210.10 1 186 1.4E-61 T 11-10-2018 UP12_11645 1c961f65d0ee7522279b8e6104bd75a9 187 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 2.8E-69 T 11-10-2018 IPR005249 Conserved hypothetical protein CHP00488 UP12_07595 71b0581dbc22d2ea0a58ecc2efc410ff 197 Pfam PF01583 Adenylylsulphate kinase 26 178 3.1E-74 T 11-10-2018 UP12_07595 71b0581dbc22d2ea0a58ecc2efc410ff 197 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 8 192 2.3E-90 T 11-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 UP12_07595 71b0581dbc22d2ea0a58ecc2efc410ff 197 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 24 196 39.523 T 11-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 UP12_07595 71b0581dbc22d2ea0a58ecc2efc410ff 197 Gene3D G3DSA:3.40.50.300 3 196 1.1E-78 T 11-10-2018 UP12_07595 71b0581dbc22d2ea0a58ecc2efc410ff 197 SUPERFAMILY SSF52540 22 194 7.68E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16300 7deb78928f07eb13b044a4b74eab65f7 142 Gene3D G3DSA:1.10.10.10 1 141 2.0E-56 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16300 7deb78928f07eb13b044a4b74eab65f7 142 SUPERFAMILY SSF46785 2 134 3.35E-34 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_16300 7deb78928f07eb13b044a4b74eab65f7 142 Pfam PF02082 Transcriptional regulator 1 81 7.4E-24 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_18085 3be276f854bccb1aa39cdd5e8044fd2b 256 Gene3D G3DSA:3.40.50.300 1 253 3.4E-67 T 11-10-2018 UP12_18085 3be276f854bccb1aa39cdd5e8044fd2b 256 SMART SM00382 26 215 3.1E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18085 3be276f854bccb1aa39cdd5e8044fd2b 256 SUPERFAMILY SSF52540 2 232 1.25E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18085 3be276f854bccb1aa39cdd5e8044fd2b 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18085 3be276f854bccb1aa39cdd5e8044fd2b 256 Pfam PF00005 ABC transporter 17 165 4.7E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16555 2278a50cad68717d0df78947c1124316 303 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 152 2.2E-45 T 11-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 UP12_16555 2278a50cad68717d0df78947c1124316 303 Gene3D G3DSA:1.20.1330.10 40 248 6.4E-43 T 11-10-2018 UP12_16555 2278a50cad68717d0df78947c1124316 303 Pfam PF00669 Bacterial flagellin N-terminal helical region 7 140 1.2E-18 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_16555 2278a50cad68717d0df78947c1124316 303 Pfam PF00700 Bacterial flagellin C-terminal helical region 221 302 7.2E-7 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_16555 2278a50cad68717d0df78947c1124316 303 SUPERFAMILY SSF64518 1 303 6.54E-62 T 11-10-2018 UP12_16765 fc97ec74837b5b5e21dd9ec40cde67cd 421 Pfam PF01547 Bacterial extracellular solute-binding protein 48 341 1.8E-36 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein UP12_16765 fc97ec74837b5b5e21dd9ec40cde67cd 421 SUPERFAMILY SSF53850 18 407 2.95E-74 T 11-10-2018 UP12_16765 fc97ec74837b5b5e21dd9ec40cde67cd 421 Gene3D G3DSA:3.40.190.10 39 382 2.5E-152 T 11-10-2018 UP12_16765 fc97ec74837b5b5e21dd9ec40cde67cd 421 Gene3D G3DSA:3.40.190.10 156 405 2.5E-152 T 11-10-2018 UP12_11320 e030aa0974f66e8c7e3da538dac0a838 428 Pfam PF07690 Major Facilitator Superfamily 25 336 5.4E-21 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_11320 e030aa0974f66e8c7e3da538dac0a838 428 Gene3D G3DSA:1.20.1250.20 12 204 1.6E-16 T 11-10-2018 UP12_11320 e030aa0974f66e8c7e3da538dac0a838 428 SUPERFAMILY SSF103473 15 399 8.24E-32 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_11320 e030aa0974f66e8c7e3da538dac0a838 428 Gene3D G3DSA:1.20.1250.20 217 408 5.5E-6 T 11-10-2018 UP12_02960 b506265ba84dd083f5f17a0d5006964a 394 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 392 1.8E-9 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_02960 b506265ba84dd083f5f17a0d5006964a 394 Pfam PF07730 Histidine kinase 193 258 5.5E-16 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UP12_02960 b506265ba84dd083f5f17a0d5006964a 394 Gene3D G3DSA:3.30.565.10 260 394 2.2E-27 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02960 b506265ba84dd083f5f17a0d5006964a 394 SUPERFAMILY SSF55874 262 391 2.1E-17 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_02960 b506265ba84dd083f5f17a0d5006964a 394 SMART SM00387 298 393 1.0E-5 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15665 0a721e6cf31f7cd94941efc56231a1b9 163 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 154 6.2E-32 T 11-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase UP12_15665 0a721e6cf31f7cd94941efc56231a1b9 163 PIRSF PIRSF030780 1 160 1.4E-17 T 11-10-2018 IPR016956 Inner membrane protein YdjM UP12_17240 906f3d45c6958ca060457189447158da 152 Gene3D G3DSA:3.40.50.2300 1 150 1.6E-58 T 11-10-2018 UP12_17240 906f3d45c6958ca060457189447158da 152 SMART SM00226 1 144 2.9E-43 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UP12_17240 906f3d45c6958ca060457189447158da 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 3.5E-8 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 UP12_17240 906f3d45c6958ca060457189447158da 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 116 131 3.5E-8 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 UP12_17240 906f3d45c6958ca060457189447158da 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 76 91 3.5E-8 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 UP12_17240 906f3d45c6958ca060457189447158da 152 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 141 1.7E-36 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UP12_17240 906f3d45c6958ca060457189447158da 152 SUPERFAMILY SSF52788 1 145 1.44E-38 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily UP12_14215 216ec7087e3cdd16c80ab29c93a9a2b4 147 Pfam PF09393 Phage tail tube protein 2 141 2.2E-53 T 11-10-2018 IPR018989 Phage tail tube protein UP12_14215 216ec7087e3cdd16c80ab29c93a9a2b4 147 Gene3D G3DSA:2.30.110.40 1 142 5.0E-61 T 11-10-2018 IPR038628 XkdM-like superfamily UP12_14215 216ec7087e3cdd16c80ab29c93a9a2b4 147 SUPERFAMILY SSF69279 6 142 2.21E-50 T 11-10-2018 UP12_07395 24c747ef53bec10e5c20d304e850a190 229 Gene3D G3DSA:3.30.70.1880 90 226 9.2E-32 T 11-10-2018 UP12_07395 24c747ef53bec10e5c20d304e850a190 229 Pfam PF05949 Bacterial protein of unknown function (DUF881) 91 221 1.0E-32 T 11-10-2018 IPR010273 Protein of unknown function DUF881 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 11-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 292 319 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 148 163 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 131 147 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 320 335 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 350 361 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 341 350 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 275 286 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 85 96 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 PRINTS PR00359 B-class P450 signature 194 216 6.8E-55 T 11-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 Gene3D G3DSA:1.10.630.10 1 401 6.1E-127 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 Pfam PF00067 Cytochrome P450 45 374 1.3E-34 T 11-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_18945 f96e4892eb6c016a4e7699014c8a7f1d 401 SUPERFAMILY SSF48264 22 400 1.7E-96 T 11-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 UP12_09135 4a9c082c1f99df5e381501868389a0ee 301 Pfam PF00682 HMGL-like 7 279 4.9E-47 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 UP12_09135 4a9c082c1f99df5e381501868389a0ee 301 SUPERFAMILY SSF51569 2 291 4.15E-69 T 11-10-2018 UP12_09135 4a9c082c1f99df5e381501868389a0ee 301 Gene3D G3DSA:3.20.20.70 1 301 1.0E-117 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_01515 118515d37ec696f99528ab848d5d7778 377 SUPERFAMILY SSF51735 155 339 1.6E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_01515 118515d37ec696f99528ab848d5d7778 377 SUPERFAMILY SSF50129 2 176 1.12E-59 T 11-10-2018 IPR011032 GroES-like superfamily UP12_01515 118515d37ec696f99528ab848d5d7778 377 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UP12_01515 118515d37ec696f99528ab848d5d7778 377 Pfam PF00107 Zinc-binding dehydrogenase 188 255 4.8E-11 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_01515 118515d37ec696f99528ab848d5d7778 377 Gene3D G3DSA:3.40.50.720 168 337 9.4E-130 T 11-10-2018 UP12_01515 118515d37ec696f99528ab848d5d7778 377 Gene3D G3DSA:3.90.180.10 4 364 9.4E-130 T 11-10-2018 UP12_01515 118515d37ec696f99528ab848d5d7778 377 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 1.9E-30 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_01515 118515d37ec696f99528ab848d5d7778 377 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 9.7E-8 T 11-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated UP12_16745 19a8a2b8aa2d91950f9e6478b6fab675 876 Pfam PF08239 Bacterial SH3 domain 632 675 9.9E-8 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_16745 19a8a2b8aa2d91950f9e6478b6fab675 876 SMART SM00047 718 870 4.8E-54 T 11-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 UP12_16745 19a8a2b8aa2d91950f9e6478b6fab675 876 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 731 859 1.2E-10 T 11-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 UP12_16745 19a8a2b8aa2d91950f9e6478b6fab675 876 Gene3D G3DSA:1.10.530.10 727 863 2.9E-7 T 11-10-2018 UP12_16745 19a8a2b8aa2d91950f9e6478b6fab675 876 Pfam PF05036 Sporulation related domain 233 303 3.0E-4 T 11-10-2018 IPR007730 Sporulation-like domain GO:0042834 UP12_16745 19a8a2b8aa2d91950f9e6478b6fab675 876 SMART SM00287 624 695 1.1E-7 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type UP12_16745 19a8a2b8aa2d91950f9e6478b6fab675 876 Gene3D G3DSA:2.30.30.40 623 688 1.5E-10 T 11-10-2018 UP12_13680 2ca28d4042bb3b8f6ec9950629c31326 232 SMART SM00382 34 222 1.3E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_13680 2ca28d4042bb3b8f6ec9950629c31326 232 Gene3D G3DSA:3.40.50.300 1 229 1.4E-70 T 11-10-2018 UP12_13680 2ca28d4042bb3b8f6ec9950629c31326 232 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_13680 2ca28d4042bb3b8f6ec9950629c31326 232 SUPERFAMILY SSF52540 1 225 2.1E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13680 2ca28d4042bb3b8f6ec9950629c31326 232 Pfam PF00005 ABC transporter 25 173 6.9E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_02445 20b1de89f7171fe4512ef7d62e0a1545 227 SUPERFAMILY SSF46785 170 224 3.43E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02445 20b1de89f7171fe4512ef7d62e0a1545 227 Pfam PF00072 Response regulator receiver domain 6 117 5.8E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_02445 20b1de89f7171fe4512ef7d62e0a1545 227 Gene3D G3DSA:3.40.50.2300 1 139 1.9E-32 T 11-10-2018 UP12_02445 20b1de89f7171fe4512ef7d62e0a1545 227 SMART SM00448 4 117 8.4E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_02445 20b1de89f7171fe4512ef7d62e0a1545 227 Gene3D G3DSA:1.10.10.10 163 214 2.9E-5 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02445 20b1de89f7171fe4512ef7d62e0a1545 227 PIRSF PIRSF006171 2 227 1.6E-79 T 11-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 UP12_02445 20b1de89f7171fe4512ef7d62e0a1545 227 SUPERFAMILY SSF52172 1 162 9.53E-34 T 11-10-2018 IPR011006 CheY-like superfamily UP12_14995 0cf8066de951ae0b933930c704018c79 183 Gene3D G3DSA:3.40.50.850 1 183 7.6E-52 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_14995 0cf8066de951ae0b933930c704018c79 183 SUPERFAMILY SSF52499 3 182 1.7E-50 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_14995 0cf8066de951ae0b933930c704018c79 183 Pfam PF00857 Isochorismatase family 4 179 1.2E-35 T 11-10-2018 IPR000868 Isochorismatase-like GO:0003824 UP12_00645 91ecd9f17ab50c83cf86125313c40399 58 Hamap MF_00422 Protein translocase subunit SecE [secE]. 1 56 12.86 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00645 91ecd9f17ab50c83cf86125313c40399 58 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 3 57 1.7E-21 T 11-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 UP12_00645 91ecd9f17ab50c83cf86125313c40399 58 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 5 57 1.6E-19 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 UP12_00645 91ecd9f17ab50c83cf86125313c40399 58 Gene3D G3DSA:1.20.5.1030 1 58 3.4E-19 T 11-10-2018 IPR038379 SecE superfamily UP12_00475 f20556ad8d20812538bf722ecf1e8ce8 77 SUPERFAMILY SSF47413 4 67 3.58E-18 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_00475 f20556ad8d20812538bf722ecf1e8ce8 77 Pfam PF01381 Helix-turn-helix 10 64 7.0E-16 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_00475 f20556ad8d20812538bf722ecf1e8ce8 77 SMART SM00530 9 64 1.7E-16 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_00475 f20556ad8d20812538bf722ecf1e8ce8 77 Gene3D G3DSA:1.10.260.40 1 66 3.2E-18 T 11-10-2018 UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 443 453 - T 11-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 SUPERFAMILY SSF53335 75 460 8.52E-79 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 Gene3D G3DSA:3.40.50.150 88 455 2.1E-113 T 11-10-2018 UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 Pfam PF01938 TRAM domain 11 65 9.0E-12 T 11-10-2018 IPR002792 TRAM domain UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 SUPERFAMILY SSF50249 5 65 2.46E-15 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 Gene3D G3DSA:2.40.50.140 2 86 3.6E-24 T 11-10-2018 UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 392 423 - T 11-10-2018 IPR030390 RNA methyltransferase TrmA, active site UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 Gene3D G3DSA:3.40.1350.30 137 293 2.1E-113 T 11-10-2018 UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 23 453 4.1E-192 T 11-10-2018 UP12_04080 95fa5875b4aa9ec45af65c7e0ef9a4dd 461 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 218 460 3.1E-20 T 11-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 UP12_06195 dea030e03f8c5604b0f7f81609fa4dcd 457 PIRSF PIRSF006304 2 454 5.0E-177 T 11-10-2018 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 UP12_06195 dea030e03f8c5604b0f7f81609fa4dcd 457 Pfam PF03611 PTS system sugar-specific permease component 9 391 6.3E-85 T 11-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 UP12_08250 10ea41b02087bc87b09806653231132b 430 SUPERFAMILY SSF63411 280 428 1.73E-16 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UP12_08250 10ea41b02087bc87b09806653231132b 430 Gene3D G3DSA:3.30.830.10 9 239 1.2E-58 T 11-10-2018 UP12_08250 10ea41b02087bc87b09806653231132b 430 Pfam PF05193 Peptidase M16 inactive domain 184 362 2.6E-17 T 11-10-2018 IPR007863 Peptidase M16, C-terminal UP12_08250 10ea41b02087bc87b09806653231132b 430 SUPERFAMILY SSF63411 15 221 5.59E-41 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UP12_08250 10ea41b02087bc87b09806653231132b 430 Gene3D G3DSA:3.30.830.10 240 427 5.2E-37 T 11-10-2018 UP12_08250 10ea41b02087bc87b09806653231132b 430 Pfam PF00675 Insulinase (Peptidase family M16) 66 177 2.2E-18 T 11-10-2018 IPR011765 Peptidase M16, N-terminal UP12_13400 ed8aa08dbb2b36a07d82878412893855 210 PIRSF PIRSF021278 2 210 2.0E-86 T 11-10-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 UP12_13400 ed8aa08dbb2b36a07d82878412893855 210 SUPERFAMILY SSF55729 30 119 7.67E-9 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_13400 ed8aa08dbb2b36a07d82878412893855 210 Pfam PF00583 Acetyltransferase (GNAT) family 47 118 1.7E-4 T 11-10-2018 IPR000182 GNAT domain UP12_13400 ed8aa08dbb2b36a07d82878412893855 210 Gene3D G3DSA:3.40.630.30 2 210 9.8E-87 T 11-10-2018 UP12_15305 fdc1b842c5243fbf343a5c482b9a59c2 317 Gene3D G3DSA:3.40.50.1980 32 141 4.9E-33 T 11-10-2018 UP12_15305 fdc1b842c5243fbf343a5c482b9a59c2 317 SUPERFAMILY SSF53807 37 311 5.89E-61 T 11-10-2018 UP12_15305 fdc1b842c5243fbf343a5c482b9a59c2 317 Gene3D G3DSA:3.40.50.1980 142 317 2.8E-61 T 11-10-2018 UP12_15305 fdc1b842c5243fbf343a5c482b9a59c2 317 Pfam PF01497 Periplasmic binding protein 55 289 4.9E-25 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 TIGRFAM TIGR01312 XylB: xylulokinase 5 483 3.3E-185 T 11-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 SUPERFAMILY SSF53067 248 488 1.5E-64 T 11-10-2018 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 Gene3D G3DSA:3.30.420.40 248 491 1.3E-76 T 11-10-2018 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 SUPERFAMILY SSF53067 1 246 1.9E-75 T 11-10-2018 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 131 143 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 354 374 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 PIRSF PIRSF000538 1 495 1.4E-163 T 11-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 Gene3D G3DSA:3.30.420.40 4 247 2.0E-82 T 11-10-2018 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 246 1.8E-70 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 UP12_09360 2a47bf3f7bf43245f8ee5eeced84cc7f 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 441 3.2E-33 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 PRINTS PR00173 Glutamate-aspartate symporter signature 143 165 1.5E-36 T 11-10-2018 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 1.5E-36 T 11-10-2018 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 PRINTS PR00173 Glutamate-aspartate symporter signature 217 236 1.5E-36 T 11-10-2018 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 1.5E-36 T 11-10-2018 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 PRINTS PR00173 Glutamate-aspartate symporter signature 43 63 1.5E-36 T 11-10-2018 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 PRINTS PR00173 Glutamate-aspartate symporter signature 73 98 1.5E-36 T 11-10-2018 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 1.5E-36 T 11-10-2018 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 SUPERFAMILY SSF118215 8 400 3.79E-119 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 35 50 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 Pfam PF00375 Sodium:dicarboxylate symporter family 8 398 2.3E-112 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 Gene3D G3DSA:1.10.3860.10 1 417 2.3E-124 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_02450 c9a092ee86b54eb8263a862cbdc1fd79 422 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 293 316 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_04075 62a6ff33fd8f605d64e035b84854d186 289 SUPERFAMILY SSF48150 105 284 5.93E-37 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 UP12_04075 62a6ff33fd8f605d64e035b84854d186 289 Gene3D G3DSA:1.10.340.30 115 233 5.3E-48 T 11-10-2018 UP12_04075 62a6ff33fd8f605d64e035b84854d186 289 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 123 271 2.2E-20 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UP12_04075 62a6ff33fd8f605d64e035b84854d186 289 SMART SM00478 126 286 1.6E-24 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 UP12_04075 62a6ff33fd8f605d64e035b84854d186 289 Gene3D G3DSA:1.10.1670.40 98 283 5.3E-48 T 11-10-2018 UP12_15380 471553cfdd97aa5ba9641d6002dd40dc 148 SUPERFAMILY SSF82649 1 138 4.45E-52 T 11-10-2018 UP12_15380 471553cfdd97aa5ba9641d6002dd40dc 148 Gene3D G3DSA:3.90.1010.10 1 147 6.3E-63 T 11-10-2018 UP12_15380 471553cfdd97aa5ba9641d6002dd40dc 148 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 7 138 4.1E-58 T 11-10-2018 UP12_15380 471553cfdd97aa5ba9641d6002dd40dc 148 Pfam PF01592 NifU-like N terminal domain 11 128 1.0E-40 T 11-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 UP12_15835 22840534254e12ffb04fb044348f131f 132 Pfam PF13560 Helix-turn-helix domain 3 61 1.1E-13 T 11-10-2018 UP12_15835 22840534254e12ffb04fb044348f131f 132 Gene3D G3DSA:1.10.260.40 1 91 3.5E-16 T 11-10-2018 UP12_15835 22840534254e12ffb04fb044348f131f 132 SUPERFAMILY SSF47413 1 63 8.16E-15 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_15835 22840534254e12ffb04fb044348f131f 132 SMART SM00530 6 62 4.1E-12 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_11600 1a43d1e84877505dc5d8253655d75964 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.19 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_11600 1a43d1e84877505dc5d8253655d75964 88 SUPERFAMILY SSF46992 3 86 6.67E-29 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_11600 1a43d1e84877505dc5d8253655d75964 88 Pfam PF01649 Ribosomal protein S20 2 84 7.5E-27 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_11600 1a43d1e84877505dc5d8253655d75964 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.2E-31 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_11600 1a43d1e84877505dc5d8253655d75964 88 Gene3D G3DSA:1.20.58.110 1 87 1.3E-29 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_11600 1a43d1e84877505dc5d8253655d75964 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 88 2.0E-24 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_18385 b1875a64286cbfb7d895995b31b36a04 291 SUPERFAMILY SSF74650 3 290 6.91E-49 T 11-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 UP12_18385 b1875a64286cbfb7d895995b31b36a04 291 Gene3D G3DSA:2.70.98.10 2 291 2.2E-94 T 11-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 UP12_18385 b1875a64286cbfb7d895995b31b36a04 291 Pfam PF01263 Aldose 1-epimerase 4 237 1.6E-24 T 11-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 UP12_03640 4b65abf386cf05f319f2eb30ba61d60a 254 SUPERFAMILY SSF53697 82 245 1.62E-20 T 11-10-2018 UP12_03640 4b65abf386cf05f319f2eb30ba61d60a 254 Pfam PF01380 SIS domain 113 218 1.0E-14 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_03640 4b65abf386cf05f319f2eb30ba61d60a 254 SUPERFAMILY SSF46689 6 74 5.73E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_03640 4b65abf386cf05f319f2eb30ba61d60a 254 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 71 4.7E-14 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_03640 4b65abf386cf05f319f2eb30ba61d60a 254 Gene3D G3DSA:1.10.10.10 2 74 5.0E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03640 4b65abf386cf05f319f2eb30ba61d60a 254 Gene3D G3DSA:3.40.50.10490 81 252 1.1E-21 T 11-10-2018 UP12_07830 7d1dbade91de7f7be92d0449836c542b 91 SUPERFAMILY SSF160544 5 86 4.71E-24 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal UP12_07830 7d1dbade91de7f7be92d0449836c542b 91 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 82 1.1E-19 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 UP12_07830 7d1dbade91de7f7be92d0449836c542b 91 Gene3D G3DSA:3.40.1690.10 6 88 1.1E-26 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal UP12_07830 7d1dbade91de7f7be92d0449836c542b 91 TIGRFAM TIGR00789 flhB_rel: FlhB domain protein 8 88 1.1E-36 T 11-10-2018 IPR004683 Type III secretion system substrate exporter FlhB-like UP12_01830 b6a6db630d3ca690dde554d949612d36 398 Gene3D G3DSA:3.40.50.10540 4 392 2.8E-127 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily UP12_01830 b6a6db630d3ca690dde554d949612d36 398 Pfam PF02515 CoA-transferase family III 5 374 1.1E-116 T 11-10-2018 IPR003673 CoA-transferase family III GO:0003824 UP12_01830 b6a6db630d3ca690dde554d949612d36 398 SUPERFAMILY SSF89796 3 398 1.27E-122 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily UP12_01830 b6a6db630d3ca690dde554d949612d36 398 Gene3D G3DSA:3.30.1540.10 233 325 2.8E-127 T 11-10-2018 UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 253 343 1.1E-7 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 Pfam PF07730 Histidine kinase 149 215 2.6E-18 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 SMART SM00387 253 346 6.6E-6 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 SMART SM00304 73 125 8.9E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 Gene3D G3DSA:3.30.565.10 214 347 2.2E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 Gene3D G3DSA:1.10.287.130 74 201 9.0E-7 T 11-10-2018 UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 SUPERFAMILY SSF55874 220 343 1.02E-18 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_15545 9fc9ac4e4b5986e4f963237263891d77 354 PIRSF PIRSF037431 7 352 8.0E-124 T 11-10-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 UP12_15400 86b6fc889ade48c8f00718642e4257a4 122 Gene3D G3DSA:1.20.1290.10 1 118 3.6E-29 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UP12_15400 86b6fc889ade48c8f00718642e4257a4 122 SUPERFAMILY SSF69118 3 118 1.2E-26 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UP12_15400 86b6fc889ade48c8f00718642e4257a4 122 Pfam PF02627 Carboxymuconolactone decarboxylase family 29 110 5.3E-16 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UP12_17800 f933d4dd840bf93fe44498e8dde8d8e2 126 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 19 92 3.4E-14 T 11-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 UP12_17800 f933d4dd840bf93fe44498e8dde8d8e2 126 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 11 102 1.2E-32 T 11-10-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 UP12_01920 7b55ed458e422700cdf758274fdc2cdb 225 SUPERFAMILY SSF161098 20 207 2.49E-49 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01920 7b55ed458e422700cdf758274fdc2cdb 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 221 4.4E-27 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_01920 7b55ed458e422700cdf758274fdc2cdb 225 Gene3D G3DSA:1.10.3720.10 13 223 1.7E-58 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01920 7b55ed458e422700cdf758274fdc2cdb 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 116 1.3E-29 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_12245 8fb739d31f5d39f60a09ae9a9dc9ccef 112 Gene3D G3DSA:3.30.70.1490 1 112 1.7E-33 T 11-10-2018 IPR036764 Cysteine protease Prp superfamily UP12_12245 8fb739d31f5d39f60a09ae9a9dc9ccef 112 SUPERFAMILY SSF118010 1 111 1.83E-30 T 11-10-2018 IPR036764 Cysteine protease Prp superfamily UP12_12245 8fb739d31f5d39f60a09ae9a9dc9ccef 112 Pfam PF04327 Cysteine protease Prp 1 106 3.2E-25 T 11-10-2018 IPR007422 Cysteine protease Prp UP12_02760 fb86db21a75d291a2b4f6d6b55f2b60d 252 ProDom PD942754 PLASMID TRANSMEMBRANE MEMBRANE PXO2-22/BXB0021/GBAA_PXO2_0021 68 248 5.0E-28 T 11-10-2018 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 SUPERFAMILY SSF103473 7 393 1.44E-71 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 Gene3D G3DSA:1.20.1250.20 2 385 1.2E-75 T 11-10-2018 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 PRINTS PR01035 Tetracycline resistance protein signature 249 269 2.7E-23 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 PRINTS PR01035 Tetracycline resistance protein signature 159 179 2.7E-23 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 PRINTS PR01035 Tetracycline resistance protein signature 337 360 2.7E-23 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 PRINTS PR01035 Tetracycline resistance protein signature 131 153 2.7E-23 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 PRINTS PR01035 Tetracycline resistance protein signature 73 97 2.7E-23 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 PRINTS PR01035 Tetracycline resistance protein signature 16 32 2.7E-23 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_15275 4b6f16d4828e5ee664c0c0b4f389bc56 396 Pfam PF07690 Major Facilitator Superfamily 10 340 3.9E-52 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_10845 6424f51a4d9d323533ea5bd47129363a 317 Pfam PF06081 Aromatic acid exporter family member 1 2 142 2.0E-52 T 11-10-2018 IPR010343 Aromatic acid exporter family member 1 UP12_10845 6424f51a4d9d323533ea5bd47129363a 317 Gene3D G3DSA:1.20.120.940 141 314 3.3E-54 T 11-10-2018 IPR038323 Putative aromatic acid exporter, C-terminal domain superfamily UP12_10845 6424f51a4d9d323533ea5bd47129363a 317 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 310 8.5E-58 T 11-10-2018 IPR021062 Putative aromatic acid exporter, C-terminal UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 529 5.5E-17 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 Pfam PF00501 AMP-binding enzyme 14 445 6.4E-114 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 Gene3D G3DSA:3.40.50.980 37 211 8.7E-122 T 11-10-2018 UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 SUPERFAMILY SSF56801 4 543 6.02E-158 T 11-10-2018 UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 Gene3D G3DSA:2.30.38.10 354 438 8.7E-122 T 11-10-2018 UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 Gene3D G3DSA:3.30.300.30 439 542 4.4E-32 T 11-10-2018 UP12_09150 b20ea8ab8bcacc54d43da7ce723880fc 545 Gene3D G3DSA:3.40.50.980 34 353 8.7E-122 T 11-10-2018 UP12_01900 7a4b7a983200140c91098d1527169be5 305 SUPERFAMILY SSF51730 37 300 1.26E-71 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like UP12_01900 7a4b7a983200140c91098d1527169be5 305 Pfam PF01619 Proline dehydrogenase 45 294 2.5E-33 T 11-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 UP12_01900 7a4b7a983200140c91098d1527169be5 305 Gene3D G3DSA:3.20.20.530 21 305 2.9E-92 T 11-10-2018 UP12_01900 7a4b7a983200140c91098d1527169be5 305 PIRSF PIRSF000196 1 305 4.4E-126 T 11-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 SUPERFAMILY SSF51230 81 157 1.14E-21 T 11-10-2018 IPR011053 Single hybrid motif UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 114 131 - T 11-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 158 4.9E-59 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 87 100 9.3E-15 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 104 118 9.3E-15 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 119 132 9.3E-15 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 Pfam PF00364 Biotin-requiring enzyme 84 155 3.1E-21 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_11005 8c0afd4655981ecb65bb1775accb7215 160 Gene3D G3DSA:2.40.50.100 81 157 1.1E-25 T 11-10-2018 UP12_16990 dad4628f6e8ec851296facbb1d99f7c0 144 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.488 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 UP12_16990 dad4628f6e8ec851296facbb1d99f7c0 144 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 1.3E-58 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 UP12_16990 dad4628f6e8ec851296facbb1d99f7c0 144 Gene3D G3DSA:3.10.129.10 1 142 1.9E-58 T 11-10-2018 UP12_16990 dad4628f6e8ec851296facbb1d99f7c0 144 SUPERFAMILY SSF54637 1 137 8.85E-48 T 11-10-2018 IPR029069 HotDog domain superfamily UP12_16990 dad4628f6e8ec851296facbb1d99f7c0 144 Pfam PF07977 FabA-like domain 11 134 8.0E-36 T 11-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 118 9.1E-20 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.93 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 Gene3D G3DSA:2.40.50.140 128 185 9.4E-26 T 11-10-2018 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 SMART SM00841 129 184 7.2E-33 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 11-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 Gene3D G3DSA:2.40.50.140 64 127 3.2E-24 T 11-10-2018 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 7.6E-26 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 7.3E-29 T 11-10-2018 IPR013185 Translation elongation factor, KOW-like UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 SUPERFAMILY SSF50249 128 185 8.91E-18 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 SUPERFAMILY SSF50249 65 129 2.78E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 4.7E-79 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 Gene3D G3DSA:2.30.30.30 1 62 9.1E-32 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 SMART SM01185 67 121 1.9E-23 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 SUPERFAMILY SSF50104 1 62 4.63E-22 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily UP12_11055 264326c2ef67cf120f811e6bab9de08e 185 PIRSF PIRSF005901 1 185 3.3E-70 T 11-10-2018 IPR020599 Translation elongation factor P/YeiP UP12_16490 bbe9c463d10bdecad677296ee750025e 597 Gene3D G3DSA:1.20.140.70 22 179 4.2E-9 T 11-10-2018 UP12_16490 bbe9c463d10bdecad677296ee750025e 597 Pfam PF08439 Oligopeptidase F 116 178 4.3E-9 T 11-10-2018 IPR013647 Oligopeptidase F, N-terminal domain UP12_16490 bbe9c463d10bdecad677296ee750025e 597 Pfam PF01432 Peptidase family M3 203 582 1.0E-24 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 UP12_16490 bbe9c463d10bdecad677296ee750025e 597 SUPERFAMILY SSF55486 54 587 9.16E-97 T 11-10-2018 UP12_16490 bbe9c463d10bdecad677296ee750025e 597 Gene3D G3DSA:1.10.1370.20 226 597 2.7E-116 T 11-10-2018 UP12_16490 bbe9c463d10bdecad677296ee750025e 597 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 9 593 1.0E-203 T 11-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 UP12_16825 1d7ef28337d1c7ff2fe6da4b9b6502b2 381 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 205 371 5.2E-33 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_16825 1d7ef28337d1c7ff2fe6da4b9b6502b2 381 Gene3D G3DSA:3.10.450.290 27 93 4.8E-33 T 11-10-2018 UP12_16825 1d7ef28337d1c7ff2fe6da4b9b6502b2 381 Gene3D G3DSA:3.30.300.210 223 374 1.3E-45 T 11-10-2018 IPR038501 Spore germination GerAC superfamily UP12_16825 1d7ef28337d1c7ff2fe6da4b9b6502b2 381 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 6 372 1.3E-91 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 SUPERFAMILY SSF54211 3 157 1.21E-48 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 Pfam PF00288 GHMP kinases N terminal domain 87 144 7.4E-12 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 Gene3D G3DSA:3.30.230.10 1 159 3.8E-62 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 Gene3D G3DSA:3.30.70.890 162 287 7.4E-30 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 SUPERFAMILY SSF55060 161 281 9.71E-31 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 36.319 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 287 2.8E-117 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 Pfam PF08544 GHMP kinases C terminal 197 270 5.8E-10 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain UP12_00295 ceccd80162c4f36a135e26f794cda97b 289 PIRSF PIRSF010376 2 288 3.7E-100 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 UP12_01270 94c13306ae0a5218597ccdd55056b3c8 278 Pfam PF13560 Helix-turn-helix domain 32 88 1.0E-15 T 11-10-2018 UP12_01270 94c13306ae0a5218597ccdd55056b3c8 278 SMART SM00530 13 85 7.7E-6 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_01270 94c13306ae0a5218597ccdd55056b3c8 278 SUPERFAMILY SSF47413 22 84 8.13E-8 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_01270 94c13306ae0a5218597ccdd55056b3c8 278 Gene3D G3DSA:3.30.450.180 110 275 3.0E-20 T 11-10-2018 UP12_01270 94c13306ae0a5218597ccdd55056b3c8 278 Gene3D G3DSA:1.10.260.40 14 86 9.5E-9 T 11-10-2018 UP12_02745 0d31b0e07de3f43c28e040f889ab2416 130 ProDom PD295888 PLASMID MEMBRANE TRANSMEMBRANE PXO2-26/BXB0024/GBAA_PXO2_0024 28 111 2.0E-9 T 11-10-2018 IPR020334 Uncharacterised protein family, plasmid pXO2-26 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 2.8E-19 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 Gene3D G3DSA:3.40.50.2300 162 292 1.5E-93 T 11-10-2018 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 SUPERFAMILY SSF53822 63 333 7.26E-87 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_13415 b1325739c9e6784becafa549fb5e484c 333 Gene3D G3DSA:3.40.50.2300 64 311 1.5E-93 T 11-10-2018 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 Gene3D G3DSA:1.10.260.40 3 61 1.1E-28 T 11-10-2018 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 Pfam PF13377 Periplasmic binding protein-like domain 170 332 2.5E-38 T 11-10-2018 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 11-10-2018 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 SMART SM00354 3 73 7.3E-39 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 SUPERFAMILY SSF47413 3 61 6.88E-20 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 TIGRFAM TIGR01481 ccpA: catabolite control protein A 3 333 1.3E-162 T 11-10-2018 IPR006377 Catabolite control protein A GO:0006355 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 4.4E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_13415 b1325739c9e6784becafa549fb5e484c 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 4.4E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_19095 867cf48b52edcc89f5d49d19b24d464e 181 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 181 1.8E-52 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UP12_19095 867cf48b52edcc89f5d49d19b24d464e 181 SUPERFAMILY SSF50249 1 181 5.14E-57 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_19095 867cf48b52edcc89f5d49d19b24d464e 181 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 36.804 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 UP12_19095 867cf48b52edcc89f5d49d19b24d464e 181 PIRSF PIRSF002070 1 170 4.2E-38 T 11-10-2018 UP12_19095 867cf48b52edcc89f5d49d19b24d464e 181 Pfam PF00436 Single-strand binding protein family 2 103 5.5E-38 T 11-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 UP12_19095 867cf48b52edcc89f5d49d19b24d464e 181 Gene3D G3DSA:2.40.50.140 1 110 2.0E-46 T 11-10-2018 UP12_18920 339fa649710fc075664f23d573858bc3 174 Gene3D G3DSA:3.40.30.10 2 167 1.1E-35 T 11-10-2018 UP12_18920 339fa649710fc075664f23d573858bc3 174 PIRSF PIRSF000239 1 169 1.1E-18 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_18920 339fa649710fc075664f23d573858bc3 174 SUPERFAMILY SSF52833 2 162 4.63E-37 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_18920 339fa649710fc075664f23d573858bc3 174 Pfam PF00578 AhpC/TSA family 7 139 1.3E-25 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_11875 40ae6a16699afb575f080f0c1b9470b6 200 SUPERFAMILY SSF53335 5 191 5.37E-31 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_11875 40ae6a16699afb575f080f0c1b9470b6 200 Gene3D G3DSA:3.40.50.150 9 200 9.5E-33 T 11-10-2018 UP12_11875 40ae6a16699afb575f080f0c1b9470b6 200 Pfam PF08241 Methyltransferase domain 49 147 3.6E-17 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UP12_10335 6db1aa076528bdd1354565a55c574f92 262 Gene3D G3DSA:3.60.21.10 50 240 1.5E-22 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_10335 6db1aa076528bdd1354565a55c574f92 262 SUPERFAMILY SSF56300 50 256 1.11E-30 T 11-10-2018 UP12_10335 6db1aa076528bdd1354565a55c574f92 262 Pfam PF00149 Calcineurin-like phosphoesterase 51 205 5.8E-13 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_10505 f1c3b733501b455737888675148b8883 294 Pfam PF06207 Protein of unknown function (DUF1002) 36 254 2.7E-77 T 11-10-2018 IPR009343 Protein of unknown function DUF1002 UP12_09730 f81d31bfbf31c2756e130fdfe8a69f01 65 Pfam PF17431 Uncharacterized ympT 1 61 4.7E-25 T 11-10-2018 IPR035403 Uncharacterized protein YmpT UP12_09730 f81d31bfbf31c2756e130fdfe8a69f01 65 ProDom PD054146 YPMT TRANSMEMBRANE MEMBRANE 1 62 9.0E-8 T 11-10-2018 IPR035403 Uncharacterized protein YmpT UP12_09950 dc94c04e105a66442a6c99dde0df3c09 204 Pfam PF06908 Protein of unknown function (DUF1273) 28 192 1.2E-71 T 11-10-2018 IPR010697 Protein of unknown function DUF1273 UP12_09950 dc94c04e105a66442a6c99dde0df3c09 204 Gene3D G3DSA:3.40.50.450 24 200 3.9E-68 T 11-10-2018 UP12_09950 dc94c04e105a66442a6c99dde0df3c09 204 Hamap MF_01575 UPF0398 protein . 25 198 35.753 T 11-10-2018 IPR010697 Protein of unknown function DUF1273 UP12_09950 dc94c04e105a66442a6c99dde0df3c09 204 PIRSF PIRSF021290 25 200 6.4E-71 T 11-10-2018 IPR010697 Protein of unknown function DUF1273 UP12_09950 dc94c04e105a66442a6c99dde0df3c09 204 SUPERFAMILY SSF102405 25 195 4.21E-63 T 11-10-2018 UP12_00815 e6a5804fffd72c586bde6dfbda548e97 60 SUPERFAMILY SSF55129 3 59 8.37E-21 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily UP12_00815 e6a5804fffd72c586bde6dfbda548e97 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 55 3.1E-20 T 11-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain UP12_00815 e6a5804fffd72c586bde6dfbda548e97 60 PIRSF PIRSF002211 1 60 7.7E-29 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00815 e6a5804fffd72c586bde6dfbda548e97 60 Gene3D G3DSA:3.30.1390.20 1 59 1.8E-27 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily UP12_00815 e6a5804fffd72c586bde6dfbda548e97 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 11-10-2018 IPR018038 Ribosomal protein L30, conserved site UP12_00815 e6a5804fffd72c586bde6dfbda548e97 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 5 59 8.2E-26 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00815 e6a5804fffd72c586bde6dfbda548e97 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 19.773 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_06745 10459bc4af83e73e649d9e7501f8c51a 708 Gene3D G3DSA:3.90.1310.30 69 593 2.4E-194 T 11-10-2018 UP12_06745 10459bc4af83e73e649d9e7501f8c51a 708 SUPERFAMILY SSF56519 61 344 4.97E-29 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 UP12_06745 10459bc4af83e73e649d9e7501f8c51a 708 Gene3D G3DSA:1.10.10.1230 94 220 2.4E-194 T 11-10-2018 UP12_06745 10459bc4af83e73e649d9e7501f8c51a 708 SUPERFAMILY SSF56601 346 702 1.15E-60 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_06745 10459bc4af83e73e649d9e7501f8c51a 708 Gene3D G3DSA:3.40.710.10 344 685 2.4E-194 T 11-10-2018 UP12_06745 10459bc4af83e73e649d9e7501f8c51a 708 Pfam PF03717 Penicillin-binding Protein dimerisation domain 67 329 1.9E-25 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 UP12_06745 10459bc4af83e73e649d9e7501f8c51a 708 Pfam PF00905 Penicillin binding protein transpeptidase domain 375 680 1.6E-66 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 Gene3D G3DSA:1.20.1640.10 142 335 1.1E-11 T 11-10-2018 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 Gene3D G3DSA:1.20.1640.10 868 1023 4.9E-11 T 11-10-2018 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 Pfam PF03176 MMPL family 47 363 6.5E-61 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 Pfam PF03176 MMPL family 742 1038 8.0E-44 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 SUPERFAMILY SSF58104 488 738 8.37E-7 T 11-10-2018 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 SUPERFAMILY SSF82866 151 338 3.66E-33 T 11-10-2018 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 Gene3D G3DSA:3.30.70.1440 821 867 4.9E-11 T 11-10-2018 UP12_08260 81438987e37bc7a00108c0363d4808bd 1039 SUPERFAMILY SSF82866 826 1032 7.06E-32 T 11-10-2018 UP12_06005 9a4c69189217541313a9615cc19afc89 276 Pfam PF14568 SMI1-KNR4 cell-wall 20 143 2.7E-22 T 11-10-2018 UP12_06005 9a4c69189217541313a9615cc19afc89 276 SUPERFAMILY SSF160631 1 150 9.42E-23 T 11-10-2018 UP12_06005 9a4c69189217541313a9615cc19afc89 276 SMART SM00860 17 145 4.7E-9 T 11-10-2018 IPR018958 Knr4/Smi1-like domain UP12_06005 9a4c69189217541313a9615cc19afc89 276 Gene3D G3DSA:3.40.1580.10 1 156 3.3E-24 T 11-10-2018 IPR037883 Knr4/Smi1-like domain superfamily UP12_18300 4fed20fa2d99d0712a6a8acf1a739644 279 Gene3D G3DSA:1.10.287.950 91 277 1.5E-37 T 11-10-2018 UP12_18300 4fed20fa2d99d0712a6a8acf1a739644 279 SMART SM00283 95 274 1.9E-4 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_18300 4fed20fa2d99d0712a6a8acf1a739644 279 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 146 270 6.2E-26 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_18300 4fed20fa2d99d0712a6a8acf1a739644 279 SUPERFAMILY SSF58104 88 273 1.11E-38 T 11-10-2018 UP12_14110 ab5af7793cde5e7d8fac15093a7c3453 185 SUPERFAMILY SSF46785 13 162 1.68E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_14110 ab5af7793cde5e7d8fac15093a7c3453 185 Gene3D G3DSA:1.10.10.10 13 94 1.5E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_14110 ab5af7793cde5e7d8fac15093a7c3453 185 PIRSF PIRSF006707 1 185 4.7E-52 T 11-10-2018 IPR026282 DNA-binding protein, MJ1563 type UP12_06055 3948315e27af35d4606b4831ff0795a7 189 Gene3D G3DSA:1.10.10.60 5 51 7.0E-17 T 11-10-2018 UP12_06055 3948315e27af35d4606b4831ff0795a7 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 8.1E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_06055 3948315e27af35d4606b4831ff0795a7 189 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_06055 3948315e27af35d4606b4831ff0795a7 189 Gene3D G3DSA:1.10.357.10 53 182 3.3E-31 T 11-10-2018 UP12_06055 3948315e27af35d4606b4831ff0795a7 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.4E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_06055 3948315e27af35d4606b4831ff0795a7 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.4E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_06055 3948315e27af35d4606b4831ff0795a7 189 SUPERFAMILY SSF46689 3 76 5.64E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_06055 3948315e27af35d4606b4831ff0795a7 189 SUPERFAMILY SSF48498 84 179 7.63E-20 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_04310 7825b6208aaa2f96d280aa27b81f60b5 90 Pfam PF14043 WVELL protein 3 76 9.3E-40 T 11-10-2018 IPR026952 WVELL protein UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 Pfam PF00406 Adenylate kinase 5 190 6.1E-61 T 11-10-2018 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.12 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 SUPERFAMILY SSF52540 1 213 2.88E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 PRINTS PR00094 Adenylate kinase signature 160 175 3.1E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 PRINTS PR00094 Adenylate kinase signature 32 46 3.1E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 PRINTS PR00094 Adenylate kinase signature 177 191 3.1E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 PRINTS PR00094 Adenylate kinase signature 4 17 3.1E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 PRINTS PR00094 Adenylate kinase signature 81 97 3.1E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 2.7E-81 T 11-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 Gene3D G3DSA:3.40.50.300 1 213 1.4E-83 T 11-10-2018 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 3.8E-19 T 11-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 UP12_00830 d4ca3e064654a57322dbf3f3320dbd1e 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 11-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 UP12_01875 6d581000a837cd9897e936f60d348a15 298 SUPERFAMILY SSF46785 2 107 1.55E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_01875 6d581000a837cd9897e936f60d348a15 298 SUPERFAMILY SSF53850 87 296 5.69E-39 T 11-10-2018 UP12_01875 6d581000a837cd9897e936f60d348a15 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 57 1.8E-19 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_01875 6d581000a837cd9897e936f60d348a15 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 35 6.7E-11 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_01875 6d581000a837cd9897e936f60d348a15 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 6.7E-11 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_01875 6d581000a837cd9897e936f60d348a15 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 14 25 6.7E-11 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_01875 6d581000a837cd9897e936f60d348a15 298 Pfam PF03466 LysR substrate binding domain 86 296 6.4E-50 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_01875 6d581000a837cd9897e936f60d348a15 298 Gene3D G3DSA:1.10.10.10 1 82 1.2E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01875 6d581000a837cd9897e936f60d348a15 298 Gene3D G3DSA:3.40.190.290 88 298 2.8E-54 T 11-10-2018 UP12_13530 5611f83b809283c6f5d7b199c305e962 208 Pfam PF03575 Peptidase family S51 11 200 6.1E-51 T 11-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 UP12_13530 5611f83b809283c6f5d7b199c305e962 208 SUPERFAMILY SSF52317 2 168 3.36E-22 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_13530 5611f83b809283c6f5d7b199c305e962 208 Gene3D G3DSA:3.40.50.880 1 205 1.7E-58 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_11190 aff46a3c960d41ad5f2c23dd643f6d51 371 SUPERFAMILY SSF52540 20 301 1.9E-68 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11190 aff46a3c960d41ad5f2c23dd643f6d51 371 Pfam PF00437 Type II/IV secretion system protein 28 289 6.9E-73 T 11-10-2018 IPR001482 Type II/IV secretion system protein UP12_11190 aff46a3c960d41ad5f2c23dd643f6d51 371 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 219 233 - T 11-10-2018 IPR001482 Type II/IV secretion system protein UP12_11190 aff46a3c960d41ad5f2c23dd643f6d51 371 Gene3D G3DSA:3.40.50.300 125 348 4.8E-65 T 11-10-2018 UP12_11190 aff46a3c960d41ad5f2c23dd643f6d51 371 Gene3D G3DSA:3.30.450.90 11 124 5.7E-30 T 11-10-2018 UP12_11190 aff46a3c960d41ad5f2c23dd643f6d51 371 SMART SM00382 151 274 1.1E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_05860 e23351886ecbc4143c04cef6a28ba326 163 Pfam PF10612 Spore coat protein Z 1 144 1.8E-44 T 11-10-2018 IPR019593 Spore coat protein Z/Y UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 SUPERFAMILY SSF118215 6 394 9.68E-111 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 33 48 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 PRINTS PR00173 Glutamate-aspartate symporter signature 184 203 4.9E-34 T 11-10-2018 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 PRINTS PR00173 Glutamate-aspartate symporter signature 286 312 4.9E-34 T 11-10-2018 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 4.9E-34 T 11-10-2018 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 PRINTS PR00173 Glutamate-aspartate symporter signature 71 96 4.9E-34 T 11-10-2018 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 PRINTS PR00173 Glutamate-aspartate symporter signature 321 340 4.9E-34 T 11-10-2018 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 PRINTS PR00173 Glutamate-aspartate symporter signature 348 368 4.9E-34 T 11-10-2018 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 Gene3D G3DSA:1.10.3860.10 1 412 1.0E-125 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_16185 32d3ba0c872bba01e63333a12970e7ab 413 Pfam PF00375 Sodium:dicarboxylate symporter family 7 393 1.2E-123 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UP12_13925 f10b1c039ed151b2315710cfe63b3f37 244 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 6 159 8.6E-55 T 11-10-2018 IPR014240 Regulatory protein, YteA family UP12_13925 f10b1c039ed151b2315710cfe63b3f37 244 SUPERFAMILY SSF109635 2 87 3.14E-12 T 11-10-2018 IPR037187 DksA, N-terminal domain superfamily UP12_13925 f10b1c039ed151b2315710cfe63b3f37 244 Gene3D G3DSA:1.20.120.910 1 125 1.2E-28 T 11-10-2018 UP12_13925 f10b1c039ed151b2315710cfe63b3f37 244 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 86 114 7.7E-7 T 11-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 UP12_13925 f10b1c039ed151b2315710cfe63b3f37 244 SUPERFAMILY SSF57716 88 119 2.0E-5 T 11-10-2018 UP12_06495 3c7e3ad04a24faf59e13ab1fd2d76d30 263 Pfam PF03741 Integral membrane protein TerC family 15 203 6.4E-52 T 11-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 UP12_06495 3c7e3ad04a24faf59e13ab1fd2d76d30 263 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 244 4.6E-93 T 11-10-2018 IPR022493 Integral membrane YkoY UP12_02690 6726a30627db51bf6ba5ed88459adce8 127 Gene3D G3DSA:2.40.50.390 2 113 9.0E-34 T 11-10-2018 IPR038620 YdcP-like superfamily UP12_02690 6726a30627db51bf6ba5ed88459adce8 127 Pfam PF06125 Bacterial protein of unknown function (DUF961) 4 105 9.1E-30 T 11-10-2018 IPR010365 Protein of unknown function DUF961 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 Gene3D G3DSA:3.40.1110.10 346 465 1.1E-86 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 Pfam PF00702 haloacid dehalogenase-like hydrolase 334 547 1.3E-40 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 Gene3D G3DSA:2.70.150.20 127 239 9.1E-37 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 SUPERFAMILY SSF56784 333 632 5.77E-56 T 11-10-2018 IPR036412 HAD-like superfamily UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 106 614 1.1E-84 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 Pfam PF00122 E1-E2 ATPase 134 313 2.7E-48 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00941 Cadmium-transporting ATPase signature 46 63 2.3E-12 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00941 Cadmium-transporting ATPase signature 118 138 2.3E-12 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00941 Cadmium-transporting ATPase signature 200 216 2.3E-12 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00941 Cadmium-transporting ATPase signature 219 233 2.3E-12 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00941 Cadmium-transporting ATPase signature 63 75 2.3E-12 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 SUPERFAMILY SSF81665 85 614 1.7E-14 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 SUPERFAMILY SSF81653 141 234 8.24E-27 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 83 635 1.3E-183 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 1.8E-31 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 458 469 1.8E-31 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 490 1.8E-31 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 1.8E-31 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 1.8E-31 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 184 198 1.8E-31 T 11-10-2018 UP12_06680 90ad3fee01a1aaec6544bfdf513eda3f 639 Gene3D G3DSA:3.40.50.1000 316 584 1.1E-86 T 11-10-2018 IPR023214 HAD superfamily UP12_00035 b575c846aab26e25440071b5bb31c293 833 SUPERFAMILY SSF56719 31 488 6.8E-183 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 33 472 3.1E-161 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Gene3D G3DSA:2.120.10.90 497 809 1.2E-124 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal UP12_00035 b575c846aab26e25440071b5bb31c293 833 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 809 0.0 T 11-10-2018 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 810 24.974 T 11-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Gene3D G3DSA:3.30.1360.40 237 333 2.5E-219 T 11-10-2018 UP12_00035 b575c846aab26e25440071b5bb31c293 833 SMART SM00434 12 465 1.3E-292 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_00035 b575c846aab26e25440071b5bb31c293 833 SUPERFAMILY SSF101904 500 824 3.66E-111 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal UP12_00035 b575c846aab26e25440071b5bb31c293 833 Gene3D G3DSA:3.90.199.10 33 486 2.5E-219 T 11-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Gene3D G3DSA:1.10.268.10 370 459 2.5E-219 T 11-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 710 756 1.0E-11 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 555 604 5.0E-9 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 762 808 2.6E-10 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 660 705 5.8E-14 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 612 656 9.5E-7 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_00035 b575c846aab26e25440071b5bb31c293 833 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 506 550 4.5E-14 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_08615 4c3b11f892f470bef69181b65beede50 473 Gene3D G3DSA:3.40.50.10420 122 277 8.7E-15 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily UP12_08615 4c3b11f892f470bef69181b65beede50 473 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UP12_08615 4c3b11f892f470bef69181b65beede50 473 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 473 63.753 T 11-10-2018 IPR022825 Lactate utilization protein B UP12_08615 4c3b11f892f470bef69181b65beede50 473 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 454 6.7E-201 T 11-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 UP12_08615 4c3b11f892f470bef69181b65beede50 473 Pfam PF13183 4Fe-4S dicluster domain 310 376 4.6E-8 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UP12_08615 4c3b11f892f470bef69181b65beede50 473 Pfam PF11870 Domain of unknown function (DUF3390) 384 470 9.7E-24 T 11-10-2018 IPR024569 4Fe-4S binding protein, C-terminal UP12_08615 4c3b11f892f470bef69181b65beede50 473 Pfam PF02589 LUD domain 72 294 1.5E-53 T 11-10-2018 IPR003741 LUD domain UP12_08615 4c3b11f892f470bef69181b65beede50 473 SUPERFAMILY SSF46548 283 392 7.32E-16 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_08615 4c3b11f892f470bef69181b65beede50 473 SUPERFAMILY SSF100950 64 295 4.18E-37 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_17610 a0d1e779fb386cef7848513b2ffcef52 235 Gene3D G3DSA:2.60.120.10 15 124 7.0E-93 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_17610 a0d1e779fb386cef7848513b2ffcef52 235 Gene3D G3DSA:2.60.120.10 11 225 7.0E-93 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_17610 a0d1e779fb386cef7848513b2ffcef52 235 Pfam PF07883 Cupin domain 41 106 1.0E-8 T 11-10-2018 IPR013096 Cupin 2, conserved barrel UP12_17610 a0d1e779fb386cef7848513b2ffcef52 235 Pfam PF07883 Cupin domain 152 211 2.6E-8 T 11-10-2018 IPR013096 Cupin 2, conserved barrel UP12_17610 a0d1e779fb386cef7848513b2ffcef52 235 SUPERFAMILY SSF51182 10 226 2.19E-27 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_17965 8f6319213909d56d262fbd796d991074 475 Gene3D G3DSA:2.160.20.10 35 458 1.0E-61 T 11-10-2018 IPR012334 Pectin lyase fold UP12_17965 8f6319213909d56d262fbd796d991074 475 SUPERFAMILY SSF51126 49 469 2.33E-63 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_17965 8f6319213909d56d262fbd796d991074 475 Pfam PF07602 Protein of unknown function (DUF1565) 40 268 3.2E-10 T 11-10-2018 IPR011459 Domain of unknown function DUF1565 UP12_17965 8f6319213909d56d262fbd796d991074 475 SMART SM00710 317 339 4.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_17965 8f6319213909d56d262fbd796d991074 475 SMART SM00710 347 369 4900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_17965 8f6319213909d56d262fbd796d991074 475 SMART SM00710 289 310 130.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_17965 8f6319213909d56d262fbd796d991074 475 SMART SM00710 219 241 490.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_17965 8f6319213909d56d262fbd796d991074 475 SMART SM00710 254 288 1100.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_17965 8f6319213909d56d262fbd796d991074 475 SMART SM00710 156 185 56.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_13695 fd84b6972a935d590f42a7777376cfed 130 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 3.1E-17 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_13695 fd84b6972a935d590f42a7777376cfed 130 Gene3D G3DSA:1.10.10.10 9 125 1.5E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_13695 fd84b6972a935d590f42a7777376cfed 130 SUPERFAMILY SSF46785 5 79 1.39E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_13695 fd84b6972a935d590f42a7777376cfed 130 SMART SM00345 16 75 6.8E-16 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Gene3D G3DSA:3.30.1490.360 27 93 1.3E-24 T 11-10-2018 UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Gene3D G3DSA:3.30.160.610 97 179 9.5E-26 T 11-10-2018 UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Pfam PF17482 Phage tail sheath C-terminal domain 340 448 1.0E-25 T 11-10-2018 IPR020287 Tail sheath protein, C-terminal domain UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Gene3D G3DSA:3.40.50.11790 190 361 1.4E-61 T 11-10-2018 UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 97 181 5.2E-14 T 11-10-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Gene3D G3DSA:3.30.360.90 377 448 9.3E-19 T 11-10-2018 UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 184 333 3.3E-38 T 11-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 Gene3D G3DSA:1.10.10.2290 251 331 1.4E-61 T 11-10-2018 UP12_14595 6ae135ff6722215087c7de9565fd51a3 448 ProDom PD032508 PHAGE-LIKE PBSX XKDK ELEMENT PHAGE LIN1278 SHEATH YQBL RELATED TAIL 315 448 2.0E-56 T 11-10-2018 IPR020287 Tail sheath protein, C-terminal domain UP12_06675 ff2086d879df08a67d31ecb5f304f897 162 Pfam PF00578 AhpC/TSA family 31 144 9.7E-20 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_06675 ff2086d879df08a67d31ecb5f304f897 162 Gene3D G3DSA:3.40.30.10 20 161 4.6E-36 T 11-10-2018 UP12_06675 ff2086d879df08a67d31ecb5f304f897 162 SUPERFAMILY SSF52833 40 159 2.48E-29 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_06675 ff2086d879df08a67d31ecb5f304f897 162 ProSitePatterns PS00194 Thioredoxin family active site. 55 73 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 UP12_02365 64eb4cc120f3f0db3aa47ea726ba450b 283 SMART SM00267 121 283 4.1E-11 T 11-10-2018 IPR000160 GGDEF domain UP12_02365 64eb4cc120f3f0db3aa47ea726ba450b 283 Pfam PF00990 Diguanylate cyclase, GGDEF domain 133 279 1.7E-19 T 11-10-2018 IPR000160 GGDEF domain UP12_02365 64eb4cc120f3f0db3aa47ea726ba450b 283 Gene3D G3DSA:3.30.70.270 118 281 8.0E-18 T 11-10-2018 UP12_02365 64eb4cc120f3f0db3aa47ea726ba450b 283 SUPERFAMILY SSF55073 138 277 6.51E-14 T 11-10-2018 IPR029787 Nucleotide cyclase UP12_05090 302d41fa7a337dcd9bf892b0f84aeca7 118 Gene3D G3DSA:1.20.120.20 27 118 7.0E-6 T 11-10-2018 UP12_05090 302d41fa7a337dcd9bf892b0f84aeca7 118 Pfam PF12732 YtxH-like protein 8 72 6.4E-11 T 11-10-2018 IPR024623 Uncharacterised protein family YtxH UP12_05090 302d41fa7a337dcd9bf892b0f84aeca7 118 SUPERFAMILY SSF47162 44 111 3.92E-6 T 11-10-2018 UP12_10005 50fc636913cc04f8e5443ba9caf9dd25 203 Pfam PF03838 Recombination protein U 31 193 1.5E-64 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 UP12_10005 50fc636913cc04f8e5443ba9caf9dd25 203 TIGRFAM TIGR00648 recU: recombination protein U 30 196 5.2E-80 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 UP12_10005 50fc636913cc04f8e5443ba9caf9dd25 203 Gene3D G3DSA:3.40.1350.10 34 203 7.7E-71 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 UP12_10005 50fc636913cc04f8e5443ba9caf9dd25 203 PIRSF PIRSF037785 24 203 1.2E-74 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 UP12_10005 50fc636913cc04f8e5443ba9caf9dd25 203 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 203 99.431 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 UP12_10005 50fc636913cc04f8e5443ba9caf9dd25 203 SUPERFAMILY SSF52980 34 196 5.9E-66 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UP12_16720 79708f4bf2e14516bf8b579ce1e5c0a3 755 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 378 751 1.8E-131 T 11-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 UP12_16720 79708f4bf2e14516bf8b579ce1e5c0a3 755 Gene3D G3DSA:3.40.50.12580 555 737 1.9E-142 T 11-10-2018 UP12_16720 79708f4bf2e14516bf8b579ce1e5c0a3 755 SUPERFAMILY SSF53756 485 675 5.18E-10 T 11-10-2018 UP12_16720 79708f4bf2e14516bf8b579ce1e5c0a3 755 Gene3D G3DSA:3.40.50.11820 383 744 1.9E-142 T 11-10-2018 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 148 2.0E-72 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 PIRSF PIRSF006160 1 156 2.0E-60 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 32.345 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 8.0E-40 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 8.0E-40 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 8.0E-40 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 8.0E-40 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 8.0E-40 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 Gene3D G3DSA:3.30.1360.80 1 157 2.0E-62 T 11-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 150 4.2E-51 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_13840 5bddd2e223d68f64a0c91cac15c429e1 157 SUPERFAMILY SSF63411 4 150 1.92E-58 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 SUPERFAMILY SSF46894 144 214 2.31E-20 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 SMART SM00421 151 208 1.0E-22 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 3.0E-20 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 SMART SM00448 3 116 1.7E-34 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 3.1E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 3.1E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 3.1E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 SUPERFAMILY SSF52172 2 131 3.27E-35 T 11-10-2018 IPR011006 CheY-like superfamily UP12_02965 8206d1e2dc354659767c7ff743d30578 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 Gene3D G3DSA:3.40.50.12740 4 214 2.0E-62 T 11-10-2018 UP12_02965 8206d1e2dc354659767c7ff743d30578 216 Pfam PF00072 Response regulator receiver domain 5 115 1.2E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_02605 1a00658be0c9aa4f2087a25f095bb13d 345 SUPERFAMILY SSF52922 201 337 3.4E-42 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_02605 1a00658be0c9aa4f2087a25f095bb13d 345 SUPERFAMILY SSF52518 2 216 3.93E-64 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_02605 1a00658be0c9aa4f2087a25f095bb13d 345 Pfam PF02780 Transketolase, C-terminal domain 206 328 2.0E-42 T 11-10-2018 IPR033248 Transketolase, C-terminal domain UP12_02605 1a00658be0c9aa4f2087a25f095bb13d 345 Gene3D G3DSA:3.40.50.920 205 337 7.2E-48 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_02605 1a00658be0c9aa4f2087a25f095bb13d 345 SMART SM00861 5 192 3.8E-59 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_02605 1a00658be0c9aa4f2087a25f095bb13d 345 Gene3D G3DSA:3.40.50.970 3 204 4.5E-80 T 11-10-2018 UP12_02605 1a00658be0c9aa4f2087a25f095bb13d 345 Pfam PF02779 Transketolase, pyrimidine binding domain 4 191 3.4E-54 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 SUPERFAMILY SSF54897 40 98 5.78E-6 T 11-10-2018 UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 177 187 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 SUPERFAMILY SSF52743 120 383 1.7E-86 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 Gene3D G3DSA:3.30.70.80 32 104 7.3E-13 T 11-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 143 153 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 PRINTS PR00723 Subtilisin serine protease family (S8) signature 138 157 5.1E-17 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 186 5.1E-17 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 PRINTS PR00723 Subtilisin serine protease family (S8) signature 328 344 5.1E-17 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 Gene3D G3DSA:3.40.50.200 117 384 1.4E-86 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 Pfam PF00082 Subtilase family 138 379 1.4E-51 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 329 339 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 Gene3D G3DSA:1.10.10.1270 439 491 7.4E-8 T 11-10-2018 UP12_01495 4b029d5c5d7640019f07baa8538b9972 543 Gene3D G3DSA:1.10.10.1270 492 543 1.1E-8 T 11-10-2018 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 ProSitePatterns PS00123 Alkaline phosphatase active site. 102 110 - T 11-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 SUPERFAMILY SSF53649 26 460 1.37E-110 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 Pfam PF00245 Alkaline phosphatase 48 460 4.1E-108 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 PRINTS PR00113 Alkaline phosphatase signature 256 285 2.4E-27 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 PRINTS PR00113 Alkaline phosphatase signature 102 117 2.4E-27 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 PRINTS PR00113 Alkaline phosphatase signature 139 159 2.4E-27 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 PRINTS PR00113 Alkaline phosphatase signature 189 199 2.4E-27 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 PRINTS PR00113 Alkaline phosphatase signature 47 67 2.4E-27 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 Gene3D G3DSA:3.40.720.10 51 451 4.6E-129 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 SMART SM00098 48 463 1.1E-137 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_03560 dcf886848e17ce1b7f431eb764eb4ff1 468 Gene3D G3DSA:1.10.60.40 332 422 4.6E-129 T 11-10-2018 UP12_09755 0ad03406a15975c578f743efebd2df01 83 Pfam PF10751 Protein of unknown function (DUF2535) 2 83 1.2E-39 T 11-10-2018 IPR019687 Protein of unknown function DUF2535 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 PIRSF PIRSF000106 35 407 1.2E-84 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 SUPERFAMILY SSF53223 6 158 4.82E-56 T 11-10-2018 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 SMART SM00919 160 384 3.2E-133 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 11-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 SUPERFAMILY SSF51735 160 405 1.55E-84 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 6.3E-26 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 Gene3D G3DSA:3.40.50.10380 1 157 4.5E-74 T 11-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 Gene3D G3DSA:3.40.50.720 158 410 6.4E-89 T 11-10-2018 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 SMART SM01274 15 148 2.8E-82 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UP12_13125 2d0cb2c52c9a6af0ea17e1200eb984e6 410 Pfam PF00390 Malic enzyme, N-terminal domain 16 148 9.9E-30 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 UP12_11310 ca2bab52b277b563e6e17df77bbc3cf1 305 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 11 288 6.9E-83 T 11-10-2018 IPR011862 Phosphate binding protein GO:0042301 UP12_11310 ca2bab52b277b563e6e17df77bbc3cf1 305 SUPERFAMILY SSF53850 49 297 2.36E-73 T 11-10-2018 UP12_11310 ca2bab52b277b563e6e17df77bbc3cf1 305 Gene3D G3DSA:3.40.190.10 51 289 8.5E-89 T 11-10-2018 UP12_11310 ca2bab52b277b563e6e17df77bbc3cf1 305 Pfam PF12849 PBP superfamily domain 43 275 8.5E-42 T 11-10-2018 IPR024370 PBP domain UP12_11310 ca2bab52b277b563e6e17df77bbc3cf1 305 Gene3D G3DSA:3.40.190.10 123 245 8.5E-89 T 11-10-2018 UP12_04875 087ebb2e1a186323460bf33e976140ba 163 SUPERFAMILY SSF88659 94 157 2.24E-14 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_04875 087ebb2e1a186323460bf33e976140ba 163 TIGRFAM TIGR02950 SigM_subfam: RNA polymerase sigma factor, SigM family 2 156 6.3E-68 T 11-10-2018 IPR014296 RNA polymerase sigma-M, bacillaceae GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_04875 087ebb2e1a186323460bf33e976140ba 163 Gene3D G3DSA:1.10.10.10 95 158 3.1E-15 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04875 087ebb2e1a186323460bf33e976140ba 163 Pfam PF04542 Sigma-70 region 2 6 72 4.7E-19 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_04875 087ebb2e1a186323460bf33e976140ba 163 Pfam PF08281 Sigma-70, region 4 103 152 1.9E-12 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_04875 087ebb2e1a186323460bf33e976140ba 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 153 8.4E-31 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_04875 087ebb2e1a186323460bf33e976140ba 163 Gene3D G3DSA:1.10.1740.10 2 74 6.3E-22 T 11-10-2018 UP12_04875 087ebb2e1a186323460bf33e976140ba 163 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 28 58 - T 11-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_04875 087ebb2e1a186323460bf33e976140ba 163 SUPERFAMILY SSF88946 4 81 7.46E-22 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 7 427 34.694 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 SUPERFAMILY SSF55205 2 423 3.6E-135 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 ProSitePatterns PS00104 EPSP synthase signature 1. 85 99 - T 11-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 PIRSF PIRSF000505 1 428 4.1E-122 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 Gene3D G3DSA:3.65.10.10 10 420 8.9E-158 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 11-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 5 420 6.2E-125 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 11 426 3.3E-133 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 UP12_10140 b30ceaf882f2b21c266b6ee74dbca635 428 Gene3D G3DSA:3.65.10.10 19 227 8.9E-158 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UP12_15985 6149cf7cd486133ec0903843734ef519 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 267 4.0E-29 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_15985 6149cf7cd486133ec0903843734ef519 277 Gene3D G3DSA:1.10.3720.10 66 271 1.2E-27 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15985 6149cf7cd486133ec0903843734ef519 277 SUPERFAMILY SSF161098 70 259 1.19E-29 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15985 6149cf7cd486133ec0903843734ef519 277 TIGRFAM TIGR02790 nickel_nikC: nickel ABC transporter, permease subunit NikC 17 270 5.6E-116 T 11-10-2018 IPR014157 Nickel ABC transporter, permease subunit NikC GO:0015099|GO:0016021 UP12_12975 79e8702405b9d7ccc71068da45aa7f8a 147 Pfam PF03788 LrgA family 21 112 1.1E-23 T 11-10-2018 IPR005538 LrgA/CidA family GO:0016021 UP12_01550 fbf95cbc5ce385ac672de6eb54fbe170 326 SUPERFAMILY SSF56601 11 326 7.88E-120 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_01550 fbf95cbc5ce385ac672de6eb54fbe170 326 Pfam PF04960 Glutaminase 31 326 1.1E-106 T 11-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 UP12_01550 fbf95cbc5ce385ac672de6eb54fbe170 326 Gene3D G3DSA:1.10.1500.10 70 207 6.3E-122 T 11-10-2018 UP12_01550 fbf95cbc5ce385ac672de6eb54fbe170 326 Gene3D G3DSA:3.40.710.10 42 326 6.3E-122 T 11-10-2018 UP12_01550 fbf95cbc5ce385ac672de6eb54fbe170 326 TIGRFAM TIGR03814 Gln_ase: glutaminase A 17 326 1.1E-120 T 11-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 UP12_01550 fbf95cbc5ce385ac672de6eb54fbe170 326 Hamap MF_00313 Glutaminase [glsA]. 13 326 44.286 T 11-10-2018 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: R-HSA-210500|Reactome: R-HSA-5628897|Reactome: R-HSA-70614 UP12_05825 affb02daefd7fae6bcdc66f02d760c4d 67 Pfam PF02597 ThiS family 3 67 1.6E-10 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 UP12_05825 affb02daefd7fae6bcdc66f02d760c4d 67 SUPERFAMILY SSF54285 2 66 1.05E-16 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UP12_05825 affb02daefd7fae6bcdc66f02d760c4d 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 67 2.8E-20 T 11-10-2018 IPR010035 ThiS, thiamine-biosynthesis UP12_05825 affb02daefd7fae6bcdc66f02d760c4d 67 Gene3D G3DSA:3.10.20.30 2 67 3.8E-19 T 11-10-2018 IPR012675 Beta-grasp domain superfamily UP12_00395 66cf30ec10fc98131b219e59caa0a708 827 SMART SM00332 601 802 1.8E-4 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_00395 66cf30ec10fc98131b219e59caa0a708 827 SUPERFAMILY SSF81606 597 805 1.18E-20 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_00395 66cf30ec10fc98131b219e59caa0a708 827 Gene3D G3DSA:3.60.40.10 586 827 9.2E-54 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_00395 66cf30ec10fc98131b219e59caa0a708 827 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 620 804 2.9E-35 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_00395 66cf30ec10fc98131b219e59caa0a708 827 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 42 804 6.9E-297 T 11-10-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_00395 66cf30ec10fc98131b219e59caa0a708 827 SMART SM00331 592 804 8.8E-42 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_09120 35c199c88c6c6f33ba8f18e5cd5d12cb 646 ProSitePatterns PS00455 Putative AMP-binding domain signature. 262 273 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_09120 35c199c88c6c6f33ba8f18e5cd5d12cb 646 Gene3D G3DSA:3.30.300.30 515 643 1.5E-27 T 11-10-2018 UP12_09120 35c199c88c6c6f33ba8f18e5cd5d12cb 646 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 86 1.0E-10 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 UP12_09120 35c199c88c6c6f33ba8f18e5cd5d12cb 646 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 1.2E-23 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_09120 35c199c88c6c6f33ba8f18e5cd5d12cb 646 Gene3D G3DSA:3.40.50.12780 63 513 2.4E-87 T 11-10-2018 UP12_09120 35c199c88c6c6f33ba8f18e5cd5d12cb 646 Pfam PF00501 AMP-binding enzyme 96 519 4.5E-70 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_09120 35c199c88c6c6f33ba8f18e5cd5d12cb 646 SUPERFAMILY SSF56801 32 620 9.94E-147 T 11-10-2018 UP12_18460 e9a0cd701526f8399eb897fd3f81be1a 442 Pfam PF02447 GntP family permease 1 440 1.9E-166 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UP12_18460 e9a0cd701526f8399eb897fd3f81be1a 442 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 2 442 3.8E-159 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UP12_18460 e9a0cd701526f8399eb897fd3f81be1a 442 PIRSF PIRSF002746 1 442 6.4E-159 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UP12_07855 cd640178b85b4004b67b8db89a3f6c8f 434 SUPERFAMILY SSF51905 7 366 8.43E-28 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_07855 cd640178b85b4004b67b8db89a3f6c8f 434 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 5 433 37.25 T 11-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 UP12_07855 cd640178b85b4004b67b8db89a3f6c8f 434 Pfam PF01134 Glucose inhibited division protein A 5 367 3.6E-119 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 UP12_07855 cd640178b85b4004b67b8db89a3f6c8f 434 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 336 359 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 UP12_07855 cd640178b85b4004b67b8db89a3f6c8f 434 Gene3D G3DSA:3.50.50.60 2 177 8.6E-59 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_07855 cd640178b85b4004b67b8db89a3f6c8f 434 Gene3D G3DSA:3.50.50.60 291 434 6.9E-53 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_07855 cd640178b85b4004b67b8db89a3f6c8f 434 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 4 433 1.7E-244 T 11-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 Pfam PF03471 Transporter associated domain 353 427 2.0E-16 T 11-10-2018 IPR005170 Transporter-associated domain UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 SMART SM01091 351 428 3.4E-22 T 11-10-2018 IPR005170 Transporter-associated domain UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 Pfam PF01595 Domain of unknown function DUF21 8 201 4.6E-50 T 11-10-2018 IPR002550 CNNM, transmembrane domain UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 SUPERFAMILY SSF56176 349 427 1.01E-16 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 SUPERFAMILY SSF54631 204 338 1.09E-33 T 11-10-2018 UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 Gene3D G3DSA:3.30.465.10 345 426 6.4E-16 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 Gene3D G3DSA:3.10.580.10 195 344 1.7E-51 T 11-10-2018 UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 Pfam PF00571 CBS domain 282 335 7.7E-7 T 11-10-2018 IPR000644 CBS domain UP12_14760 4e5e45add3b41a504d1bbde722c0ef47 430 Pfam PF00571 CBS domain 222 272 3.4E-6 T 11-10-2018 IPR000644 CBS domain UP12_01415 d969260c2a69987988efb72bfed15b0d 887 SMART SM00872 275 353 7.9E-9 T 11-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 UP12_01415 d969260c2a69987988efb72bfed15b0d 887 Pfam PF09261 Alpha mannosidase middle domain 276 350 8.2E-8 T 11-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 UP12_01415 d969260c2a69987988efb72bfed15b0d 887 Gene3D G3DSA:1.20.1270.50 278 378 7.0E-26 T 11-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 UP12_01415 d969260c2a69987988efb72bfed15b0d 887 SUPERFAMILY SSF88713 3 268 2.17E-54 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_01415 d969260c2a69987988efb72bfed15b0d 887 Gene3D G3DSA:2.70.98.30 480 766 1.0E-81 T 11-10-2018 UP12_01415 d969260c2a69987988efb72bfed15b0d 887 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 382 882 1.1E-34 T 11-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 UP12_01415 d969260c2a69987988efb72bfed15b0d 887 SUPERFAMILY SSF88688 276 372 8.17E-11 T 11-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily UP12_01415 d969260c2a69987988efb72bfed15b0d 887 Gene3D G3DSA:3.20.110.10 1 272 4.6E-102 T 11-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily UP12_01415 d969260c2a69987988efb72bfed15b0d 887 SUPERFAMILY SSF74650 369 885 1.32E-69 T 11-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 UP12_01415 d969260c2a69987988efb72bfed15b0d 887 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 4 264 3.2E-49 T 11-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 UP12_14785 469efee29a14ef9951a01bf8da050e17 72 Pfam PF10676 Spore germination protein gerPA/gerPF 5 54 2.1E-7 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF UP12_14625 a17ee522e8e72de26fd2bd0546098bb4 307 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 301 1.5E-10 T 11-10-2018 IPR024455 Phage capsid UP12_14625 a17ee522e8e72de26fd2bd0546098bb4 307 Pfam PF05065 Phage capsid family 20 302 5.2E-32 T 11-10-2018 IPR024455 Phage capsid UP12_14625 a17ee522e8e72de26fd2bd0546098bb4 307 SUPERFAMILY SSF56563 20 301 4.45E-11 T 11-10-2018 UP12_04665 efa8937634de5df4aa57702f249d2ad6 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 2.1E-95 T 11-10-2018 IPR010650 PrkA C-terminal domain UP12_04665 efa8937634de5df4aa57702f249d2ad6 631 SMART SM00763 21 371 1.4E-197 T 11-10-2018 IPR013153 PrkA AAA domain UP12_04665 efa8937634de5df4aa57702f249d2ad6 631 PIRSF PIRSF000549 1 631 1.1E-268 T 11-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 UP12_04665 efa8937634de5df4aa57702f249d2ad6 631 SUPERFAMILY SSF52540 68 463 2.85E-11 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04665 efa8937634de5df4aa57702f249d2ad6 631 Pfam PF08298 PrkA AAA domain 22 371 2.7E-154 T 11-10-2018 IPR013153 PrkA AAA domain UP12_05185 47371318acfdc7fa507fb3bf50f2c0ec 247 Gene3D G3DSA:3.60.15.10 1 244 4.4E-84 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_05185 47371318acfdc7fa507fb3bf50f2c0ec 247 SMART SM00849 18 211 1.6E-7 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_05185 47371318acfdc7fa507fb3bf50f2c0ec 247 SUPERFAMILY SSF56281 1 242 2.54E-54 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_05185 47371318acfdc7fa507fb3bf50f2c0ec 247 Pfam PF12706 Beta-lactamase superfamily domain 30 211 3.8E-16 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_15375 870d2dab47a2ed26f6550d48e330882e 465 SUPERFAMILY SSF101960 32 462 6.54E-139 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily UP12_15375 870d2dab47a2ed26f6550d48e330882e 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 1.8E-230 T 11-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 UP12_15375 870d2dab47a2ed26f6550d48e330882e 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 1.1E-74 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 UP12_16485 889a6e05785e3774741fdc31ceec135e 244 SUPERFAMILY SSF53474 63 238 3.3E-17 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_16485 889a6e05785e3774741fdc31ceec135e 244 Pfam PF12695 Alpha/beta hydrolase family 63 226 2.8E-60 T 11-10-2018 IPR029059 Alpha/beta hydrolase fold-5 UP12_16485 889a6e05785e3774741fdc31ceec135e 244 Gene3D G3DSA:3.40.50.1820 30 242 1.1E-17 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_09900 1295b6ae7a8e2af09003d59e8057e4f7 168 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 73 163 7.4E-30 T 11-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 UP12_09900 1295b6ae7a8e2af09003d59e8057e4f7 168 Gene3D G3DSA:1.20.120.1630 1 166 1.2E-17 T 11-10-2018 UP12_18355 4f6dbf8f18ebd3e02110e7b6aba8c198 212 Gene3D G3DSA:3.40.109.10 2 212 3.6E-63 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_18355 4f6dbf8f18ebd3e02110e7b6aba8c198 212 Pfam PF00881 Nitroreductase family 14 192 3.1E-31 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UP12_18355 4f6dbf8f18ebd3e02110e7b6aba8c198 212 SUPERFAMILY SSF55469 9 211 1.24E-60 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_03055 b13eb00ea9cee0af4cf99186675e500f 220 Pfam PF01596 O-methyltransferase 30 204 8.8E-40 T 11-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 UP12_03055 b13eb00ea9cee0af4cf99186675e500f 220 SUPERFAMILY SSF53335 4 205 3.94E-39 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_03055 b13eb00ea9cee0af4cf99186675e500f 220 Gene3D G3DSA:3.40.50.150 1 220 7.8E-74 T 11-10-2018 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 SMART SM00331 119 333 2.2E-63 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 SUPERFAMILY SSF81606 124 332 4.45E-8 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 Gene3D G3DSA:1.10.1240.30 1 84 7.3E-34 T 11-10-2018 IPR017944 KaiA/RbsU helical domain superfamily GO:0006468 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 ProDom PD685490 RSBU REGULATOR SIGMA REGULATION FACTOR B PHOSPHATASE SIGMAB INDIRECT SIGMA-B 5 91 5.0E-40 T 11-10-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 Gene3D G3DSA:3.60.40.10 88 335 6.4E-55 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 SUPERFAMILY SSF101215 2 84 1.37E-29 T 11-10-2018 IPR017944 KaiA/RbsU helical domain superfamily GO:0006468 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 145 333 6.1E-52 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02565 e837f95328e5c7e8c4b309e748055daa 335 Pfam PF08673 Phosphoserine phosphatase RsbU, N-terminal domain 9 83 3.6E-30 T 11-10-2018 IPR014787 Phosphoserine phosphatase RsbU, N-terminal KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3 UP12_16870 70fbd1bdb62bfd1e6668f1d5d12700e1 493 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 24 471 1.6E-165 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_16870 70fbd1bdb62bfd1e6668f1d5d12700e1 493 PIRSF PIRSF005690 9 485 7.4E-163 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_09175 8fa7fac0480d4df41eceb0267faa4549 129 Gene3D G3DSA:3.30.429.10 1 129 2.0E-50 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily UP12_09175 8fa7fac0480d4df41eceb0267faa4549 129 Pfam PF14552 Tautomerase enzyme 38 118 2.7E-31 T 11-10-2018 IPR037479 Tautomerase, MSAD family UP12_09175 8fa7fac0480d4df41eceb0267faa4549 129 SUPERFAMILY SSF55331 2 125 8.38E-40 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily UP12_07885 e95e7e044eb371cfab4614eb0a6875c5 150 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site UP12_07885 e95e7e044eb371cfab4614eb0a6875c5 150 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 98 147 4.7E-12 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain UP12_07885 e95e7e044eb371cfab4614eb0a6875c5 150 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 150 3.2E-49 T 11-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 UP12_07885 e95e7e044eb371cfab4614eb0a6875c5 150 Pfam PF00460 Flagella basal body rod protein 9 37 1.0E-10 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 Gene3D G3DSA:3.20.20.70 20 268 2.1E-21 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 PIRSF PIRSF005963 2 298 8.4E-135 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 SUPERFAMILY SSF102114 20 287 3.53E-62 T 11-10-2018 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 Hamap MF_00206 Lipoyl synthase [lipA]. 1 295 148.084 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 3 45 2.6E-10 T 11-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 SMART SM00729 57 265 2.3E-15 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 293 8.1E-120 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 UP12_15230 7c4e921aa5bb57aa25b66f20f0504677 298 Pfam PF04055 Radical SAM superfamily 64 224 1.5E-13 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_06525 17ebfeb8f091a82bbec4ed95d86020b8 450 Pfam PF02386 Cation transport protein 26 428 4.0E-61 T 11-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 UP12_08240 c05ffb220ee386eea5fc616de39dee1b 1038 SUPERFAMILY SSF82866 136 338 1.24E-32 T 11-10-2018 UP12_08240 c05ffb220ee386eea5fc616de39dee1b 1038 SUPERFAMILY SSF82866 810 1034 2.35E-28 T 11-10-2018 UP12_08240 c05ffb220ee386eea5fc616de39dee1b 1038 Gene3D G3DSA:1.20.1640.10 826 1030 2.5E-6 T 11-10-2018 UP12_08240 c05ffb220ee386eea5fc616de39dee1b 1038 Gene3D G3DSA:1.20.1640.10 146 344 3.8E-12 T 11-10-2018 UP12_08240 c05ffb220ee386eea5fc616de39dee1b 1038 Pfam PF03176 MMPL family 735 1035 1.8E-43 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_08240 c05ffb220ee386eea5fc616de39dee1b 1038 Pfam PF03176 MMPL family 42 365 7.9E-58 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_08315 5a68bf2c290deb14a8756926776a8fe2 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 4.7E-40 T 11-10-2018 IPR007347 Sporulation stage V, protein S UP12_08315 5a68bf2c290deb14a8756926776a8fe2 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 3.0E-32 T 11-10-2018 IPR007347 Sporulation stage V, protein S UP12_08315 5a68bf2c290deb14a8756926776a8fe2 86 Gene3D G3DSA:3.30.110.20 1 86 5.1E-36 T 11-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 UP12_05175 1ac69b3c62693790e1b4f551da531160 349 SUPERFAMILY SSF101821 74 186 1.45E-31 T 11-10-2018 UP12_05175 1ac69b3c62693790e1b4f551da531160 349 SUPERFAMILY SSF53187 7 344 1.72E-56 T 11-10-2018 UP12_05175 1ac69b3c62693790e1b4f551da531160 349 PIRSF PIRSF001123 5 345 6.2E-41 T 11-10-2018 IPR008007 Peptidase M42 UP12_05175 1ac69b3c62693790e1b4f551da531160 349 Pfam PF05343 M42 glutamyl aminopeptidase 49 337 1.6E-89 T 11-10-2018 IPR008007 Peptidase M42 UP12_05175 1ac69b3c62693790e1b4f551da531160 349 Gene3D G3DSA:2.40.30.40 77 171 1.0E-126 T 11-10-2018 IPR023367 Peptidase M42, domain 2 UP12_05175 1ac69b3c62693790e1b4f551da531160 349 Gene3D G3DSA:3.40.630.10 14 342 1.0E-126 T 11-10-2018 UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 Pfam PF00232 Glycosyl hydrolase family 1 2 475 6.9E-132 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 SUPERFAMILY SSF51445 2 471 1.18E-161 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 11-10-2018 IPR018120 Glycoside hydrolase family 1, active site UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 303 317 9.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 9.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 9.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 9.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 9.2E-18 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 7 21 - T 11-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site UP12_18715 19fc0a549bae8b37d589bab4d71d805e 478 Gene3D G3DSA:3.20.20.80 1 478 5.9E-164 T 11-10-2018 UP12_11990 46f779527042f8b5cddc9f1053489ddd 354 Pfam PF01594 AI-2E family transporter 21 346 1.8E-75 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like UP12_10100 dc9939f6e09f1936cc20354450dd5316 267 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 31 258 3.3E-88 T 11-10-2018 IPR014231 Sporulation protein YpjB UP12_10100 dc9939f6e09f1936cc20354450dd5316 267 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 31 260 9.1E-81 T 11-10-2018 IPR014231 Sporulation protein YpjB UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 SUPERFAMILY SSF52096 219 489 7.87E-75 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 Gene3D G3DSA:3.90.226.10 2 249 4.4E-82 T 11-10-2018 UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 Pfam PF01039 Carboxyl transferase domain 29 487 3.6E-154 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 SUPERFAMILY SSF52096 5 244 2.57E-70 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 Gene3D G3DSA:3.90.226.10 250 489 6.9E-78 T 11-10-2018 UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 122 140 6.2E-5 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 88 102 6.2E-5 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_10830 f16404c714bc4294d2b2e0df9f0c6f94 489 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 187 198 6.2E-5 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 2.3E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 2.3E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 2.3E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 Gene3D G3DSA:2.30.30.30 119 177 6.7E-24 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 Pfam PF00467 KOW motif 128 158 3.8E-8 T 11-10-2018 IPR005824 KOW UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 SMART SM00739 123 150 4.6E-6 T 11-10-2018 IPR005824 KOW UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 SUPERFAMILY SSF50104 121 177 3.46E-19 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 SUPERFAMILY SSF82679 2 114 1.28E-40 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 Pfam PF02357 Transcription termination factor nusG 3 109 7.2E-28 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 1.2E-68 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 SMART SM00738 2 113 3.0E-53 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.983 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 Gene3D G3DSA:3.30.70.940 1 118 7.1E-45 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 UP12_00650 03b9c247a4963c517eb086c1f14a7230 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 11-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site UP12_18765 8c54d0fcaca2d359fcfe25162ac71d25 704 Pfam PF03176 MMPL family 48 377 3.3E-59 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_18765 8c54d0fcaca2d359fcfe25162ac71d25 704 Pfam PF03176 MMPL family 430 691 5.8E-43 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_18765 8c54d0fcaca2d359fcfe25162ac71d25 704 SUPERFAMILY SSF82866 509 694 6.54E-27 T 11-10-2018 UP12_18765 8c54d0fcaca2d359fcfe25162ac71d25 704 SUPERFAMILY SSF82866 189 349 3.66E-31 T 11-10-2018 UP12_18765 8c54d0fcaca2d359fcfe25162ac71d25 704 Gene3D G3DSA:1.20.1640.10 177 350 2.2E-6 T 11-10-2018 UP12_18370 04302f1c11186de949c4ae0f40787860 393 Pfam PF07670 Nucleoside recognition 91 189 4.3E-6 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 UP12_18370 04302f1c11186de949c4ae0f40787860 393 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 192 392 2.0E-60 T 11-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 UP12_18370 04302f1c11186de949c4ae0f40787860 393 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 5 392 3.7E-138 T 11-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 UP12_18370 04302f1c11186de949c4ae0f40787860 393 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 5.8E-21 T 11-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 UP12_18380 9f1dbd67ce4957c5d4686e0f6ec8e8c0 314 Gene3D G3DSA:1.10.10.60 1 51 2.3E-20 T 11-10-2018 UP12_18380 9f1dbd67ce4957c5d4686e0f6ec8e8c0 314 Gene3D G3DSA:3.40.50.1360 52 312 2.9E-90 T 11-10-2018 UP12_18380 9f1dbd67ce4957c5d4686e0f6ec8e8c0 314 SUPERFAMILY SSF88659 13 47 1.7E-7 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_18380 9f1dbd67ce4957c5d4686e0f6ec8e8c0 314 Pfam PF04198 Putative sugar-binding domain 57 311 2.8E-84 T 11-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 UP12_18380 9f1dbd67ce4957c5d4686e0f6ec8e8c0 314 SUPERFAMILY SSF100950 56 312 4.42E-78 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_18380 9f1dbd67ce4957c5d4686e0f6ec8e8c0 314 Pfam PF04545 Sigma-70, region 4 14 47 5.2E-6 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_04260 0643ece01c2c1feb918f9b5cb84b11ee 182 Gene3D G3DSA:3.40.30.10 1 182 2.5E-19 T 11-10-2018 UP12_04260 0643ece01c2c1feb918f9b5cb84b11ee 182 SUPERFAMILY SSF52833 42 123 2.88E-8 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_04260 0643ece01c2c1feb918f9b5cb84b11ee 182 Pfam PF14595 Thioredoxin 10 137 7.8E-44 T 11-10-2018 UP12_10120 70d530b3bfd12fca5ef42335516880f4 168 Gene3D G3DSA:2.102.10.10 43 164 1.2E-22 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UP12_10120 70d530b3bfd12fca5ef42335516880f4 168 Pfam PF00355 Rieske [2Fe-2S] domain 81 148 3.0E-12 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UP12_10120 70d530b3bfd12fca5ef42335516880f4 168 Pfam PF08802 Cytochrome B6-F complex Fe-S subunit 9 36 6.3E-6 T 11-10-2018 IPR014909 Cytochrome b6-f complex Fe-S subunit GO:0009496|GO:0042651|GO:0051537|GO:0055114 KEGG: 00195+1.10.9.1|MetaCyc: PWY-101 UP12_10120 70d530b3bfd12fca5ef42335516880f4 168 SUPERFAMILY SSF50022 5 159 7.33E-30 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UP12_02115 7103941548319e6cb454e16b24900c8f 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 219 2.1E-24 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_02115 7103941548319e6cb454e16b24900c8f 224 SUPERFAMILY SSF161098 14 204 1.57E-45 T 11-10-2018 IPR035906 MetI-like superfamily UP12_02115 7103941548319e6cb454e16b24900c8f 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 113 1.0E-23 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_02115 7103941548319e6cb454e16b24900c8f 224 Gene3D G3DSA:1.10.3720.10 2 221 1.0E-60 T 11-10-2018 IPR035906 MetI-like superfamily UP12_09425 1ea35c6c271af7237ce063a375444b8c 310 Pfam PF08279 HTH domain 11 56 1.2E-11 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_09425 1ea35c6c271af7237ce063a375444b8c 310 PIRSF PIRSF016838 1 300 2.0E-23 T 11-10-2018 IPR028349 Protein PafC UP12_09425 1ea35c6c271af7237ce063a375444b8c 310 Gene3D G3DSA:1.10.10.10 1 61 8.5E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09425 1ea35c6c271af7237ce063a375444b8c 310 SUPERFAMILY SSF46785 4 58 3.18E-7 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09425 1ea35c6c271af7237ce063a375444b8c 310 Pfam PF13280 WYL domain 136 297 5.1E-29 T 11-10-2018 IPR026881 WYL domain UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 Gene3D G3DSA:3.40.50.200 3 307 3.9E-112 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 87 97 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 SUPERFAMILY SSF52743 22 287 1.03E-87 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 83 96 2.4E-23 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 243 259 2.4E-23 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 PRINTS PR00723 Subtilisin serine protease family (S8) signature 41 60 2.4E-23 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 46 57 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 Pfam PF00082 Subtilase family 41 287 6.8E-62 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_06420 b4a986c14dd2f996f98f1bddcf5c25c1 319 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 244 254 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site UP12_06180 da03bc2747f15ba6157aee7c9451d52d 152 Pfam PF04266 ASCH domain 29 149 3.5E-25 T 11-10-2018 IPR007374 ASCH domain UP12_06180 da03bc2747f15ba6157aee7c9451d52d 152 PIRSF PIRSF021320 1 152 1.7E-54 T 11-10-2018 IPR009326 Protein of unknown function DUF984 UP12_06180 da03bc2747f15ba6157aee7c9451d52d 152 SMART SM01022 29 149 8.8E-44 T 11-10-2018 IPR007374 ASCH domain UP12_06180 da03bc2747f15ba6157aee7c9451d52d 152 SUPERFAMILY SSF88697 1 149 5.96E-51 T 11-10-2018 IPR015947 PUA-like superfamily UP12_06180 da03bc2747f15ba6157aee7c9451d52d 152 Gene3D G3DSA:3.10.400.10 1 152 1.1E-57 T 11-10-2018 UP12_16905 661f5f26874baa503449747c768c1926 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 309 1.1E-52 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UP12_06540 9dea3ca37c5313d0e5e9854ac90e64c1 339 Pfam PF01757 Acyltransferase family 7 307 1.7E-21 T 11-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UP12_18860 29bd7d1bb5c86b5b42417f57d6e59c0e 293 Pfam PF00005 ABC transporter 18 156 1.7E-24 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18860 29bd7d1bb5c86b5b42417f57d6e59c0e 293 Gene3D G3DSA:3.40.50.300 1 229 2.7E-52 T 11-10-2018 UP12_18860 29bd7d1bb5c86b5b42417f57d6e59c0e 293 SUPERFAMILY SSF52540 2 209 4.89E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18860 29bd7d1bb5c86b5b42417f57d6e59c0e 293 SMART SM00382 26 199 5.4E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_10650 5f5150203bc192b7bdb963a56df20e2e 420 Pfam PF13424 Tetratricopeptide repeat 187 252 6.9E-11 T 11-10-2018 UP12_10650 5f5150203bc192b7bdb963a56df20e2e 420 SMART SM00028 180 213 67.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10650 5f5150203bc192b7bdb963a56df20e2e 420 SMART SM00028 220 253 4.7E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10650 5f5150203bc192b7bdb963a56df20e2e 420 SMART SM00028 262 295 280.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10650 5f5150203bc192b7bdb963a56df20e2e 420 SMART SM00028 139 172 43.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_10650 5f5150203bc192b7bdb963a56df20e2e 420 SUPERFAMILY SSF48452 118 309 2.96E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10650 5f5150203bc192b7bdb963a56df20e2e 420 Gene3D G3DSA:1.25.40.10 1 378 4.4E-119 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 SUPERFAMILY SSF46894 139 236 9.92E-32 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 SMART SM00862 159 235 3.5E-29 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 Gene3D G3DSA:1.10.10.10 137 241 1.4E-37 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 235 1.3E-29 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 SUPERFAMILY SSF52172 2 131 1.71E-44 T 11-10-2018 IPR011006 CheY-like superfamily UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 Gene3D G3DSA:3.40.50.2300 1 136 1.5E-41 T 11-10-2018 UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 Pfam PF00072 Response regulator receiver domain 5 114 2.7E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_13070 dc2d70a3ce5332395fdaf846ff63f1b8 242 SMART SM00448 3 114 7.6E-50 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_04600 0cbcf9b80107faa4510a7d6db141a9a9 431 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 425 1.1E-149 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_04600 0cbcf9b80107faa4510a7d6db141a9a9 431 PIRSF PIRSF001434 1 429 9.6E-131 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_04600 0cbcf9b80107faa4510a7d6db141a9a9 431 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 9 425 3.7E-212 T 11-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 UP12_04600 0cbcf9b80107faa4510a7d6db141a9a9 431 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_04600 0cbcf9b80107faa4510a7d6db141a9a9 431 Gene3D G3DSA:3.40.640.10 5 290 1.0E-104 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_04600 0cbcf9b80107faa4510a7d6db141a9a9 431 Gene3D G3DSA:3.90.1150.10 294 431 6.4E-54 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_04600 0cbcf9b80107faa4510a7d6db141a9a9 431 SUPERFAMILY SSF53383 8 425 1.84E-131 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_00910 84dfe9aec78c3fe78bfdf78b2358ffef 248 SUPERFAMILY SSF51556 2 245 4.89E-42 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_00910 84dfe9aec78c3fe78bfdf78b2358ffef 248 Gene3D G3DSA:3.20.20.140 1 247 2.0E-43 T 11-10-2018 UP12_00910 84dfe9aec78c3fe78bfdf78b2358ffef 248 Pfam PF04909 Amidohydrolase 5 246 8.6E-14 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 Gene3D G3DSA:3.40.50.880 411 625 5.8E-64 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 SUPERFAMILY SSF52317 409 618 9.61E-61 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 Pfam PF08532 Beta-galactosidase trimerisation domain 413 618 2.7E-74 T 11-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 Gene3D G3DSA:3.20.20.80 7 408 6.9E-137 T 11-10-2018 UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 SUPERFAMILY SSF51445 4 382 3.79E-111 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 Pfam PF02449 Beta-galactosidase 20 402 2.1E-153 T 11-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 PIRSF PIRSF001084 7 688 9.5E-252 T 11-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 Pfam PF08533 Beta-galactosidase C-terminal domain 629 687 3.5E-14 T 11-10-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 UP12_18535 4f619ab39f689c8b91c3eebefe8b6822 688 Gene3D G3DSA:2.60.40.1180 627 688 3.1E-18 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta UP12_13275 500772d43656bdb47cf0db4d03c2d0a2 114 Pfam PF03551 Transcriptional regulator PadR-like family 16 89 2.1E-25 T 11-10-2018 IPR005149 Transcription regulator PadR, N-terminal UP12_13275 500772d43656bdb47cf0db4d03c2d0a2 114 SUPERFAMILY SSF46785 12 108 1.02E-28 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_13275 500772d43656bdb47cf0db4d03c2d0a2 114 Gene3D G3DSA:1.10.10.10 1 113 2.6E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03810 7bc2b4586657b3f4b5e1397bd9cccc42 380 SMART SM00490 255 335 4.1E-22 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_03810 7bc2b4586657b3f4b5e1397bd9cccc42 380 SUPERFAMILY SSF52540 72 355 5.34E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03810 7bc2b4586657b3f4b5e1397bd9cccc42 380 Gene3D G3DSA:3.40.50.300 210 379 5.8E-38 T 11-10-2018 UP12_03810 7bc2b4586657b3f4b5e1397bd9cccc42 380 SMART SM00487 23 218 1.1E-51 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_03810 7bc2b4586657b3f4b5e1397bd9cccc42 380 Pfam PF00271 Helicase conserved C-terminal domain 230 335 1.2E-21 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_03810 7bc2b4586657b3f4b5e1397bd9cccc42 380 Pfam PF00270 DEAD/DEAH box helicase 28 193 9.6E-44 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_03810 7bc2b4586657b3f4b5e1397bd9cccc42 380 Gene3D G3DSA:3.40.50.300 2 208 1.8E-61 T 11-10-2018 UP12_10975 055812004c9b4e5648ab7f897a3ae2fd 86 Pfam PF02609 Exonuclease VII small subunit 14 63 1.2E-20 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UP12_10975 055812004c9b4e5648ab7f897a3ae2fd 86 Gene3D G3DSA:1.10.287.1040 7 83 9.4E-23 T 11-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 UP12_10975 055812004c9b4e5648ab7f897a3ae2fd 86 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 13 73 14.611 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UP12_10975 055812004c9b4e5648ab7f897a3ae2fd 86 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 13 68 4.0E-22 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UP12_10975 055812004c9b4e5648ab7f897a3ae2fd 86 SUPERFAMILY SSF116842 7 76 2.35E-21 T 11-10-2018 UP12_10975 055812004c9b4e5648ab7f897a3ae2fd 86 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 13 52 5.0E-14 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 Pfam PF04542 Sigma-70 region 2 55 124 9.9E-18 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 Gene3D G3DSA:1.10.10.10 155 235 1.6E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 SUPERFAMILY SSF88946 11 121 7.2E-34 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 PIRSF PIRSF000770 3 242 1.9E-93 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 PRINTS PR00046 Major sigma-70 factor signature 79 92 8.0E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 PRINTS PR00046 Major sigma-70 factor signature 213 224 8.0E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 PRINTS PR00046 Major sigma-70 factor signature 177 189 8.0E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 PRINTS PR00046 Major sigma-70 factor signature 198 213 8.0E-13 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 224 5.2E-31 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 Gene3D G3DSA:1.20.120.1810 21 124 6.6E-24 T 11-10-2018 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 79 92 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 198 224 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 Pfam PF04545 Sigma-70, region 4 174 224 7.0E-15 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 SUPERFAMILY SSF88659 140 226 3.92E-18 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_11695 2770978fe30067ef8ce52fb41a4c78c1 242 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 6 229 1.0E-114 T 11-10-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_08665 b2a59474c68ac8f3c840f5ff1fa9ba06 282 Gene3D G3DSA:3.30.750.24 163 280 2.1E-34 T 11-10-2018 IPR036513 STAS domain superfamily UP12_08665 b2a59474c68ac8f3c840f5ff1fa9ba06 282 Pfam PF01740 STAS domain 173 260 1.2E-13 T 11-10-2018 IPR002645 STAS domain UP12_08665 b2a59474c68ac8f3c840f5ff1fa9ba06 282 SUPERFAMILY SSF52091 166 275 1.35E-17 T 11-10-2018 IPR036513 STAS domain superfamily UP12_06325 6d67dfe7732139ad34cbbf11ca0de683 173 Gene3D G3DSA:3.10.129.10 1 168 1.5E-56 T 11-10-2018 UP12_06325 6d67dfe7732139ad34cbbf11ca0de683 173 Pfam PF03061 Thioesterase superfamily 28 100 1.5E-14 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UP12_06325 6d67dfe7732139ad34cbbf11ca0de683 173 SUPERFAMILY SSF54637 6 157 3.07E-45 T 11-10-2018 IPR029069 HotDog domain superfamily UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 Gene3D G3DSA:3.40.50.2300 159 288 3.6E-66 T 11-10-2018 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 Pfam PF13377 Periplasmic binding protein-like domain 167 329 1.1E-36 T 11-10-2018 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 SUPERFAMILY SSF47413 1 59 1.97E-17 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 Gene3D G3DSA:3.40.50.2300 61 305 3.6E-66 T 11-10-2018 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 SMART SM00354 1 71 6.4E-30 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.9E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.9E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 SUPERFAMILY SSF53822 60 329 2.02E-68 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.4E-19 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_01725 f17f4bda60ef671d6928badf29aa0df1 329 Gene3D G3DSA:1.10.260.40 3 59 5.9E-22 T 11-10-2018 UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 Pfam PF00005 ABC transporter 271 426 1.8E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 SUPERFAMILY SSF52540 251 479 1.78E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 SUPERFAMILY SSF52540 4 223 1.81E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 Pfam PF00005 ABC transporter 21 171 1.9E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 Gene3D G3DSA:3.40.50.300 1 241 1.1E-50 T 11-10-2018 UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 SMART SM00382 280 475 2.3E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 SMART SM00382 30 219 2.0E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17955 9f937a16e6bc3f2bde67fb75001bc980 498 Gene3D G3DSA:3.40.50.300 259 494 6.3E-46 T 11-10-2018 UP12_18575 2c3a51d1f90f6bc027cdb8d0ad284656 423 Pfam PF02447 GntP family permease 12 416 1.9E-20 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 UP12_10860 d1403e1be8217fe7c90d035bfc58ad67 254 Gene3D G3DSA:3.40.190.10 119 213 6.2E-64 T 11-10-2018 UP12_10860 d1403e1be8217fe7c90d035bfc58ad67 254 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site UP12_10860 d1403e1be8217fe7c90d035bfc58ad67 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 251 4.4E-57 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_10860 d1403e1be8217fe7c90d035bfc58ad67 254 SMART SM00079 35 252 6.2E-4 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 UP12_10860 d1403e1be8217fe7c90d035bfc58ad67 254 Gene3D G3DSA:3.40.190.10 39 249 6.2E-64 T 11-10-2018 UP12_10860 d1403e1be8217fe7c90d035bfc58ad67 254 SMART SM00062 35 253 4.0E-69 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_10860 d1403e1be8217fe7c90d035bfc58ad67 254 SUPERFAMILY SSF53850 1 251 3.02E-68 T 11-10-2018 UP12_16170 e4749b1fce145d1c702a5d49d5e30347 193 Gene3D G3DSA:3.40.1050.10 1 184 1.3E-45 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UP12_16170 e4749b1fce145d1c702a5d49d5e30347 193 SUPERFAMILY SSF53056 3 182 8.37E-41 T 11-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 UP12_16170 e4749b1fce145d1c702a5d49d5e30347 193 SMART SM00947 27 183 7.2E-37 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UP12_16170 e4749b1fce145d1c702a5d49d5e30347 193 Pfam PF00484 Carbonic anhydrase 35 178 5.6E-18 T 11-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 SUPERFAMILY SSF55681 120 588 1.15E-109 T 11-10-2018 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 SUPERFAMILY SSF50249 6 110 4.38E-33 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_12060 067adff5dc03e14d05df37414a183aa3 594 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 5 589 34.853 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 210 2.2E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 215 228 2.2E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 479 495 2.2E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 PRINTS PR01042 Aspartyl-tRNA synthetase signature 523 537 2.2E-26 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 Gene3D G3DSA:2.40.50.140 2 110 7.0E-35 T 11-10-2018 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 4 587 4.2E-268 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 Gene3D G3DSA:3.30.930.10 124 586 2.4E-197 T 11-10-2018 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 Pfam PF00152 tRNA synthetases class II (D, K and N) 125 562 2.8E-111 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 Gene3D G3DSA:3.30.1360.30 280 424 2.4E-197 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 SUPERFAMILY SSF55261 297 424 3.6E-43 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 Pfam PF02938 GAD domain 316 410 9.0E-32 T 11-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 UP12_12060 067adff5dc03e14d05df37414a183aa3 594 Pfam PF01336 OB-fold nucleic acid binding domain 22 107 5.1E-17 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 SUPERFAMILY SSF52467 199 368 1.51E-64 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 SUPERFAMILY SSF52518 377 572 4.05E-67 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 400 548 2.6E-53 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 18 179 1.1E-54 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 Gene3D G3DSA:3.40.50.970 10 190 1.9E-69 T 11-10-2018 UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 SUPERFAMILY SSF52518 15 197 2.26E-61 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 Gene3D G3DSA:3.40.50.1220 201 366 6.0E-63 T 11-10-2018 UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 207 342 4.7E-47 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 18 572 1.1E-278 T 11-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 UP12_12430 5d18e52abfaf293b861ef1bdaa9716af 574 Gene3D G3DSA:3.40.50.970 370 573 2.1E-70 T 11-10-2018 UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 SMART SM00633 99 340 1.5E-10 T 11-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 SUPERFAMILY SSF51445 50 354 1.85E-92 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 Pfam PF00331 Glycosyl hydrolase family 10 62 328 1.1E-46 T 11-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 Gene3D G3DSA:3.20.20.80 56 347 9.1E-75 T 11-10-2018 UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 PRINTS PR00134 Glycosyl hydrolase family 10 signature 130 142 4.1E-8 T 11-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 PRINTS PR00134 Glycosyl hydrolase family 10 signature 212 223 4.1E-8 T 11-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 PRINTS PR00134 Glycosyl hydrolase family 10 signature 174 185 4.1E-8 T 11-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_08100 87bed87060a25a93acb0800b54d6ee34 409 PRINTS PR00134 Glycosyl hydrolase family 10 signature 240 252 4.1E-8 T 11-10-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6717|MetaCyc: PWY-6784 UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 Pfam PF07729 FCD domain 99 225 6.0E-25 T 11-10-2018 IPR011711 GntR, C-terminal UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 SUPERFAMILY SSF48008 96 232 2.12E-29 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.3E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.3E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 SMART SM00895 99 226 5.9E-23 T 11-10-2018 IPR011711 GntR, C-terminal UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 SUPERFAMILY SSF46785 6 90 6.99E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 5.8E-20 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 Gene3D G3DSA:1.20.120.530 80 232 6.2E-31 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 Gene3D G3DSA:1.10.10.10 1 74 2.1E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15955 af5b0e3e4ccbb2e07ff526cae2f4e681 245 SMART SM00345 15 74 5.6E-21 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.9E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.9E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.9E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.9E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 9.0E-89 T 11-10-2018 UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 PIRSF PIRSF000094 2 258 1.6E-103 T 11-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 Gene3D G3DSA:3.40.50.720 1 257 1.2E-61 T 11-10-2018 UP12_05845 7e7a0dc143e83faa407263aa04c1aff7 258 SUPERFAMILY SSF51735 6 255 2.29E-67 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03230 b16d7aee4138d2f83b221d0cc7efd3e4 349 SUPERFAMILY SSF69304 71 342 3.01E-19 T 11-10-2018 UP12_03230 b16d7aee4138d2f83b221d0cc7efd3e4 349 Gene3D G3DSA:2.120.10.30 95 339 5.3E-12 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like UP12_04090 e870c91696e98b7230bdde54ed5b868f 620 Pfam PF12697 Alpha/beta hydrolase family 382 609 2.0E-13 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_04090 e870c91696e98b7230bdde54ed5b868f 620 Pfam PF07993 Male sterility protein 7 238 3.0E-38 T 11-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 UP12_04090 e870c91696e98b7230bdde54ed5b868f 620 SUPERFAMILY SSF53474 373 615 9.73E-24 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_04090 e870c91696e98b7230bdde54ed5b868f 620 Gene3D G3DSA:3.40.50.720 1 323 1.8E-39 T 11-10-2018 UP12_04090 e870c91696e98b7230bdde54ed5b868f 620 SUPERFAMILY SSF51735 1 290 1.74E-30 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_04090 e870c91696e98b7230bdde54ed5b868f 620 Gene3D G3DSA:3.40.50.1820 357 617 6.2E-26 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 SMART SM00650 36 212 7.7E-88 T 11-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 280 4.7E-81 T 11-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 Gene3D G3DSA:1.10.8.100 220 291 4.3E-21 T 11-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 SUPERFAMILY SSF53335 16 289 5.43E-75 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 Gene3D G3DSA:3.40.50.150 2 216 2.7E-74 T 11-10-2018 UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 79 - T 11-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 20 286 1.7E-87 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 UP12_00275 25760ff70fe922afdb3ad2654f10b5e5 292 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 288 56.416 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 UP12_07455 a32903fda50d3460cdcff7591f53ccfb 176 PIRSF PIRSF038321 1 176 3.2E-81 T 11-10-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 UP12_07455 a32903fda50d3460cdcff7591f53ccfb 176 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 171 1.9E-54 T 11-10-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 UP12_07455 a32903fda50d3460cdcff7591f53ccfb 176 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 4 168 8.5E-77 T 11-10-2018 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 Pfam PF00216 Bacterial DNA-binding protein 1 89 7.5E-38 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 11-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 Gene3D G3DSA:4.10.520.10 1 92 1.0E-40 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 SUPERFAMILY SSF47729 1 90 7.07E-36 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.0E-21 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.0E-21 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.0E-21 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 UP12_10235 4b64bab0fc0d7fad90fa4b477d18da2f 92 SMART SM00411 1 90 4.4E-53 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 UP12_17625 88e1c568240dcb94f3db2e28ca864887 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 UP12_17625 88e1c568240dcb94f3db2e28ca864887 397 Gene3D G3DSA:3.90.1150.10 40 381 2.4E-104 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_17625 88e1c568240dcb94f3db2e28ca864887 397 Pfam PF00155 Aminotransferase class I and II 33 383 2.4E-57 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_17625 88e1c568240dcb94f3db2e28ca864887 397 SUPERFAMILY SSF53383 5 384 1.03E-97 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_17625 88e1c568240dcb94f3db2e28ca864887 397 Gene3D G3DSA:3.40.640.10 65 286 2.4E-104 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_10775 f3f972384dffa65174ae2c70db108daa 110 Gene3D G3DSA:1.20.58.280 6 110 3.0E-35 T 11-10-2018 UP12_10775 f3f972384dffa65174ae2c70db108daa 110 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 13 105 3.3E-32 T 11-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 UP12_10775 f3f972384dffa65174ae2c70db108daa 110 PIRSF PIRSF000699 5 110 2.1E-35 T 11-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 UP12_10775 f3f972384dffa65174ae2c70db108daa 110 SUPERFAMILY SSF46973 10 106 2.62E-32 T 11-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 UP12_17410 91c84f61ee3c2a671f33457d50fa3b35 320 Gene3D G3DSA:3.20.20.150 2 307 3.5E-89 T 11-10-2018 UP12_17410 91c84f61ee3c2a671f33457d50fa3b35 320 Pfam PF03851 UV-endonuclease UvdE 5 274 5.3E-106 T 11-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 UP12_17410 91c84f61ee3c2a671f33457d50fa3b35 320 TIGRFAM TIGR00629 uvde: UV damage endonuclease UvdE 1 303 5.5E-113 T 11-10-2018 IPR004601 UV-endonuclease UvdE GO:0004519|GO:0006289|GO:0009411 UP12_17410 91c84f61ee3c2a671f33457d50fa3b35 320 SUPERFAMILY SSF51658 84 294 2.35E-12 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily UP12_17410 91c84f61ee3c2a671f33457d50fa3b35 320 Hamap MF_00606 UV DNA damage endonuclease [uvsE]. 12 304 37.64 T 11-10-2018 IPR023520 UV-endonuclease UvdE, bacterial GO:0004519|GO:0009411 UP12_11215 5038a8cdf05548c70502909fbd9ff300 80 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 6.6E-37 T 11-10-2018 IPR020254 Protein of unknown function DUF2626 UP12_11215 5038a8cdf05548c70502909fbd9ff300 80 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 79 4.0E-36 T 11-10-2018 IPR020254 Protein of unknown function DUF2626 UP12_01190 2b4378b7d7c56b7bf458d48d03f1cb45 71 SMART SM00530 6 61 6.7E-18 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_01190 2b4378b7d7c56b7bf458d48d03f1cb45 71 Pfam PF01381 Helix-turn-helix 7 59 5.6E-17 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_01190 2b4378b7d7c56b7bf458d48d03f1cb45 71 SUPERFAMILY SSF47413 1 68 2.95E-20 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_01190 2b4378b7d7c56b7bf458d48d03f1cb45 71 Gene3D G3DSA:1.10.260.40 2 65 2.0E-27 T 11-10-2018 UP12_06320 2361dbd989b2e1b883183167d3c2a980 293 Gene3D G3DSA:3.75.10.10 9 288 5.3E-76 T 11-10-2018 UP12_06320 2361dbd989b2e1b883183167d3c2a980 293 Pfam PF02274 Amidinotransferase 27 285 5.3E-46 T 11-10-2018 UP12_06320 2361dbd989b2e1b883183167d3c2a980 293 SUPERFAMILY SSF55909 13 286 9.64E-73 T 11-10-2018 UP12_17670 a6eb6a77ae17598a440d42a942292b09 291 Gene3D G3DSA:3.40.630.30 37 283 2.5E-37 T 11-10-2018 UP12_17670 a6eb6a77ae17598a440d42a942292b09 291 Pfam PF00583 Acetyltransferase (GNAT) family 191 273 2.4E-14 T 11-10-2018 IPR000182 GNAT domain UP12_17670 a6eb6a77ae17598a440d42a942292b09 291 SUPERFAMILY SSF55729 114 282 1.6E-25 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_03915 c2b92d9b76dee4ab2a1a5533bc29fbae 454 SUPERFAMILY SSF55604 378 450 1.44E-20 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_03915 c2b92d9b76dee4ab2a1a5533bc29fbae 454 Gene3D G3DSA:3.30.1360.60 373 453 3.5E-25 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_03915 c2b92d9b76dee4ab2a1a5533bc29fbae 454 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 390 407 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_03915 c2b92d9b76dee4ab2a1a5533bc29fbae 454 Pfam PF00367 phosphotransferase system, EIIB 381 412 9.9E-14 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_03915 c2b92d9b76dee4ab2a1a5533bc29fbae 454 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 353 437 8.1E-18 T 11-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UP12_03915 c2b92d9b76dee4ab2a1a5533bc29fbae 454 Pfam PF02378 Phosphotransferase system, EIIC 10 294 4.8E-79 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_03915 c2b92d9b76dee4ab2a1a5533bc29fbae 454 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 448 5.4E-179 T 11-10-2018 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 SUPERFAMILY SSF52738 163 354 1.44E-60 T 11-10-2018 IPR035909 Methylesterase CheB, C-terminal UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 SUPERFAMILY SSF52172 2 107 9.68E-29 T 11-10-2018 IPR011006 CheY-like superfamily UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 PIRSF PIRSF000876 1 357 1.6E-131 T 11-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 Pfam PF01339 CheB methylesterase 169 348 1.2E-53 T 11-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 Pfam PF00072 Response regulator receiver domain 4 109 5.0E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 Gene3D G3DSA:3.40.50.2300 1 136 4.9E-33 T 11-10-2018 UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 353 37.847 T 11-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 SMART SM00448 2 118 1.9E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_08005 734f9fb2870cf1ff7de788f9d310938c 357 Gene3D G3DSA:3.40.50.180 162 351 2.1E-62 T 11-10-2018 IPR035909 Methylesterase CheB, C-terminal UP12_19000 a5e4bdaea1fd89b3d36cd412eb5e4ad9 75 SMART SM00923 3 53 6.9E-29 T 11-10-2018 IPR005153 MbtH-like domain UP12_19000 a5e4bdaea1fd89b3d36cd412eb5e4ad9 75 Gene3D G3DSA:3.90.820.10 1 68 2.1E-32 T 11-10-2018 UP12_19000 a5e4bdaea1fd89b3d36cd412eb5e4ad9 75 SUPERFAMILY SSF160582 1 65 1.31E-28 T 11-10-2018 IPR038020 MbtH-like domain superfamily UP12_19000 a5e4bdaea1fd89b3d36cd412eb5e4ad9 75 Pfam PF03621 MbtH-like protein 1 52 1.6E-27 T 11-10-2018 IPR005153 MbtH-like domain UP12_03935 e2a70891383e58068439d49bd85de1ba 659 Gene3D G3DSA:3.40.720.10 243 551 8.2E-82 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_03935 e2a70891383e58068439d49bd85de1ba 659 PIRSF PIRSF005091 1 625 8.1E-187 T 11-10-2018 IPR012160 Lipoteichoic acid synthase-like UP12_03935 e2a70891383e58068439d49bd85de1ba 659 SUPERFAMILY SSF53649 249 639 5.42E-78 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_03935 e2a70891383e58068439d49bd85de1ba 659 Pfam PF00884 Sulfatase 252 540 5.8E-44 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 UP12_14345 2ef74cdd0e74d93ed466d8f5395d9fb6 201 Pfam PF13392 HNH endonuclease 121 165 1.3E-14 T 11-10-2018 IPR003615 HNH nuclease UP12_14345 2ef74cdd0e74d93ed466d8f5395d9fb6 201 SUPERFAMILY SSF54060 93 162 1.65E-11 T 11-10-2018 UP12_14345 2ef74cdd0e74d93ed466d8f5395d9fb6 201 Gene3D G3DSA:3.90.75.20 37 170 2.1E-5 T 11-10-2018 UP12_02530 8e844ac49446f9049bc96f3cf783e4d6 335 Gene3D G3DSA:2.50.20.10 29 208 2.6E-14 T 11-10-2018 UP12_02530 8e844ac49446f9049bc96f3cf783e4d6 335 SUPERFAMILY SSF89392 28 203 1.08E-24 T 11-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX UP12_02530 8e844ac49446f9049bc96f3cf783e4d6 335 Pfam PF14285 Domain of unknown function (DUF4367) 230 329 3.7E-6 T 11-10-2018 IPR025377 Domain of unknown function DUF4367 UP12_05655 fd63ebbd79f4bdef070f3f3ad6d2e947 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 3.9E-22 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_05655 fd63ebbd79f4bdef070f3f3ad6d2e947 326 Pfam PF00005 ABC transporter 25 183 7.1E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_05655 fd63ebbd79f4bdef070f3f3ad6d2e947 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 319 2.6E-27 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_05655 fd63ebbd79f4bdef070f3f3ad6d2e947 326 SUPERFAMILY SSF52540 4 254 3.04E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05655 fd63ebbd79f4bdef070f3f3ad6d2e947 326 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_05655 fd63ebbd79f4bdef070f3f3ad6d2e947 326 Gene3D G3DSA:3.40.50.300 1 326 9.9E-103 T 11-10-2018 UP12_05655 fd63ebbd79f4bdef070f3f3ad6d2e947 326 SMART SM00382 33 241 8.8E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00915 cda9743339617729caf7dd537782bf73 157 Pfam PF00583 Acetyltransferase (GNAT) family 33 143 1.9E-20 T 11-10-2018 IPR000182 GNAT domain UP12_00915 cda9743339617729caf7dd537782bf73 157 Gene3D G3DSA:3.40.630.30 3 154 3.5E-41 T 11-10-2018 UP12_00915 cda9743339617729caf7dd537782bf73 157 SUPERFAMILY SSF55729 6 147 8.97E-29 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_01995 7451e0053cee657eb1bac2ab5e193e90 267 Gene3D G3DSA:1.10.3720.10 9 266 1.4E-57 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01995 7451e0053cee657eb1bac2ab5e193e90 267 SUPERFAMILY SSF161098 8 260 2.24E-58 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01995 7451e0053cee657eb1bac2ab5e193e90 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 256 5.2E-15 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_16025 30d30b2e4a2643b220626f88b5ce00d5 340 Pfam PF00535 Glycosyl transferase family 2 5 167 1.8E-33 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_16025 30d30b2e4a2643b220626f88b5ce00d5 340 SUPERFAMILY SSF53448 2 231 2.53E-55 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_16025 30d30b2e4a2643b220626f88b5ce00d5 340 Gene3D G3DSA:3.90.550.10 1 202 1.2E-52 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_14835 0671843ee4f4ccfe3efe8c62547285bf 391 Pfam PF00155 Aminotransferase class I and II 45 382 1.1E-39 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_14835 0671843ee4f4ccfe3efe8c62547285bf 391 SUPERFAMILY SSF53383 9 386 1.58E-98 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_14835 0671843ee4f4ccfe3efe8c62547285bf 391 Gene3D G3DSA:3.90.1150.10 16 381 9.0E-147 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_14835 0671843ee4f4ccfe3efe8c62547285bf 391 Gene3D G3DSA:3.40.640.10 59 283 9.0E-147 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_14835 0671843ee4f4ccfe3efe8c62547285bf 391 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 3 386 1.6E-150 T 11-10-2018 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 UP12_02910 79926d573ff5fa10b2b357c1edb06711 249 SUPERFAMILY SSF46955 4 110 2.86E-20 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_02910 79926d573ff5fa10b2b357c1edb06711 249 SMART SM00422 3 72 1.2E-8 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_02910 79926d573ff5fa10b2b357c1edb06711 249 Gene3D G3DSA:1.10.1660.10 2 138 6.9E-23 T 11-10-2018 UP12_02910 79926d573ff5fa10b2b357c1edb06711 249 Pfam PF13411 MerR HTH family regulatory protein 4 70 4.2E-14 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 Gene3D G3DSA:3.40.50.300 75 214 1.7E-27 T 11-10-2018 UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 Pfam PF12848 ABC transporter 155 259 2.5E-8 T 11-10-2018 IPR032781 ABC-transporter extension domain UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 SUPERFAMILY SSF52540 12 197 1.92E-32 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 Gene3D G3DSA:3.40.50.300 7 74 7.0E-11 T 11-10-2018 UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 Pfam PF00005 ABC transporter 295 419 4.5E-17 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 SMART SM00382 303 464 4.3E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 SMART SM00382 37 160 5.9E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 Pfam PF00005 ABC transporter 32 69 1.1E-8 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 SUPERFAMILY SSF52540 264 479 1.83E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16095 62d8c7e41ffe57db5cf144b29911aaa8 529 Gene3D G3DSA:3.40.50.300 269 483 5.5E-51 T 11-10-2018 UP12_04770 63918bf2eb6c638437b1c240546b2d4b 305 Gene3D G3DSA:1.20.1530.20 157 304 7.4E-9 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily UP12_04770 63918bf2eb6c638437b1c240546b2d4b 305 Pfam PF03547 Membrane transport protein 151 295 3.1E-18 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UP12_04770 63918bf2eb6c638437b1c240546b2d4b 305 Pfam PF03547 Membrane transport protein 7 139 9.3E-9 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UP12_14495 a3bd58728a6938833e7ed02b3a58367c 427 SUPERFAMILY SSF56349 73 394 3.53E-54 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UP12_14495 a3bd58728a6938833e7ed02b3a58367c 427 Pfam PF00589 Phage integrase family 195 387 6.3E-19 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UP12_14495 a3bd58728a6938833e7ed02b3a58367c 427 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 74 135 1.8E-8 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UP12_14495 a3bd58728a6938833e7ed02b3a58367c 427 Gene3D G3DSA:1.10.150.130 67 192 1.6E-18 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal UP12_14495 a3bd58728a6938833e7ed02b3a58367c 427 Gene3D G3DSA:1.10.443.10 193 400 8.6E-46 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UP12_07740 27146135dbaf3e1fe1b3b6cc43d5a2e5 332 PIRSF PIRSF002465 1 332 7.8E-132 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UP12_07740 27146135dbaf3e1fe1b3b6cc43d5a2e5 332 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 332 153.034 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UP12_07740 27146135dbaf3e1fe1b3b6cc43d5a2e5 332 SUPERFAMILY SSF53659 1 327 3.04E-106 T 11-10-2018 UP12_07740 27146135dbaf3e1fe1b3b6cc43d5a2e5 332 Pfam PF02504 Fatty acid synthesis protein 1 317 3.7E-129 T 11-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 UP12_07740 27146135dbaf3e1fe1b3b6cc43d5a2e5 332 Gene3D G3DSA:3.40.718.10 1 332 4.4E-143 T 11-10-2018 UP12_07740 27146135dbaf3e1fe1b3b6cc43d5a2e5 332 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 328 1.5E-139 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 PIRSF PIRSF000151 1 415 1.6E-171 T 11-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 SUPERFAMILY SSF53720 2 414 6.81E-105 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 Gene3D G3DSA:3.40.309.10 224 372 3.6E-157 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 414 40.0 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 14 404 1.9E-166 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 Gene3D G3DSA:3.40.605.10 16 409 3.6E-157 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 321 343 - T 11-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_06380 aaefc434feed78c0e358dcc327eb5a8b 415 Pfam PF00171 Aldehyde dehydrogenase family 8 281 6.9E-11 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_15480 5c595d1708df1e6dedc44a36e6291d6a 276 SUPERFAMILY SSF52540 4 229 1.3E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15480 5c595d1708df1e6dedc44a36e6291d6a 276 SMART SM00382 28 225 1.9E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15480 5c595d1708df1e6dedc44a36e6291d6a 276 Gene3D G3DSA:3.40.50.300 1 251 1.1E-64 T 11-10-2018 UP12_15480 5c595d1708df1e6dedc44a36e6291d6a 276 Pfam PF00005 ABC transporter 20 167 2.6E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15480 5c595d1708df1e6dedc44a36e6291d6a 276 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 Pfam PF02743 Cache domain 44 265 8.4E-28 T 11-10-2018 IPR033479 Double Cache domain 1 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 SUPERFAMILY SSF58104 323 659 2.88E-76 T 11-10-2018 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 Gene3D G3DSA:1.10.8.500 303 354 1.3E-10 T 11-10-2018 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 SMART SM00304 303 355 1.0E-16 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 431 613 7.9E-57 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 SMART SM00319 32 151 0.0055 T 11-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 SUPERFAMILY SSF103190 87 193 3.69E-7 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 Pfam PF00672 HAMP domain 303 352 5.2E-14 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 482 509 2.2E-24 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 405 434 2.2E-24 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 511 540 2.2E-24 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 Gene3D G3DSA:1.10.287.950 355 659 5.8E-74 T 11-10-2018 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 Gene3D G3DSA:3.30.450.20 71 183 4.9E-31 T 11-10-2018 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 SMART SM00283 384 659 2.3E-101 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_14720 f6e0a236523ae4afeef2a4421e4fb0f4 662 Gene3D G3DSA:3.30.450.20 60 265 4.9E-31 T 11-10-2018 UP12_09445 32900587f7eebcd7b5bbde55b99578f2 220 SUPERFAMILY SSF53955 53 164 8.44E-10 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_09445 32900587f7eebcd7b5bbde55b99578f2 220 Gene3D G3DSA:1.10.530.10 47 202 3.0E-48 T 11-10-2018 UP12_09445 32900587f7eebcd7b5bbde55b99578f2 220 Pfam PF13702 Lysozyme-like 49 202 1.0E-57 T 11-10-2018 UP12_08495 56aaa2e20069209a485a50cdfb5ae6e5 136 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08495 56aaa2e20069209a485a50cdfb5ae6e5 136 SMART SM00422 12 80 7.2E-27 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08495 56aaa2e20069209a485a50cdfb5ae6e5 136 Pfam PF13411 MerR HTH family regulatory protein 13 78 4.9E-18 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08495 56aaa2e20069209a485a50cdfb5ae6e5 136 Gene3D G3DSA:1.10.1660.10 1 84 1.2E-25 T 11-10-2018 UP12_08495 56aaa2e20069209a485a50cdfb5ae6e5 136 SUPERFAMILY SSF46955 12 98 2.75E-18 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_16700 9eddfa1bdbffd1930ba79e7390888433 293 Pfam PF00483 Nucleotidyl transferase 6 265 8.7E-34 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UP12_16700 9eddfa1bdbffd1930ba79e7390888433 293 SUPERFAMILY SSF53448 4 275 1.31E-67 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_16700 9eddfa1bdbffd1930ba79e7390888433 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 264 2.3E-122 T 11-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 UP12_16700 9eddfa1bdbffd1930ba79e7390888433 293 Gene3D G3DSA:3.90.550.10 1 291 3.4E-93 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_18955 89331e46b60e0110400bb8571effa765 454 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 4.1E-35 T 11-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 UP12_18955 89331e46b60e0110400bb8571effa765 454 SUPERFAMILY SSF48024 8 119 1.44E-37 T 11-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 UP12_18955 89331e46b60e0110400bb8571effa765 454 Gene3D G3DSA:3.40.50.300 167 454 7.8E-122 T 11-10-2018 UP12_18955 89331e46b60e0110400bb8571effa765 454 SMART SM00382 202 391 0.0039 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18955 89331e46b60e0110400bb8571effa765 454 Gene3D G3DSA:1.10.860.10 1 166 3.8E-65 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal UP12_18955 89331e46b60e0110400bb8571effa765 454 SUPERFAMILY SSF52540 183 433 1.24E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18955 89331e46b60e0110400bb8571effa765 454 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 9.3E-120 T 11-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 UP12_18955 89331e46b60e0110400bb8571effa765 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 9 442 9.3E-189 T 11-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 292 31.595 T 11-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 Pfam PF01351 Ribonuclease HII 81 285 4.8E-54 T 11-10-2018 IPR024567 Ribonuclease HII/HIII domain UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 Gene3D G3DSA:3.30.310.10 1 70 1.5E-22 T 11-10-2018 IPR012295 TBP domain superfamily UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 Pfam PF11858 Domain of unknown function (DUF3378) 1 62 2.0E-22 T 11-10-2018 IPR024568 Ribonuclease HIII, N-terminal UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 Gene3D G3DSA:3.30.420.10 78 291 6.8E-78 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 2 284 9.2E-103 T 11-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 PIRSF PIRSF037748 1 292 1.4E-113 T 11-10-2018 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 UP12_12910 0a9679ad1ea9d6c051d98ed10eabd09f 292 SUPERFAMILY SSF53098 79 290 3.03E-48 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_11370 745007a5bd1328223afd896b4e346215 142 SUPERFAMILY SSF46785 5 133 5.99E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_11370 745007a5bd1328223afd896b4e346215 142 Gene3D G3DSA:3.30.1490.190 87 141 2.9E-14 T 11-10-2018 UP12_11370 745007a5bd1328223afd896b4e346215 142 Pfam PF01475 Ferric uptake regulator family 12 129 1.0E-28 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 UP12_11370 745007a5bd1328223afd896b4e346215 142 Gene3D G3DSA:1.10.10.10 1 83 9.1E-18 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08510 b11f84c026143e62011183d7b08a8177 421 Gene3D G3DSA:2.60.120.40 277 416 4.7E-7 T 11-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 UP12_14150 e68b64cadde028ccedb44ba3ebf480a0 47 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 8 45 2.0E-13 T 11-10-2018 IPR010022 Protein of unknown function XkdX UP12_14150 e68b64cadde028ccedb44ba3ebf480a0 47 TIGRFAM TIGR01669 phage_XkdX: phage uncharacterized protein, XkdX family 1 45 5.7E-13 T 11-10-2018 IPR010022 Protein of unknown function XkdX UP12_06405 5b05b8e2136855b6d33f54d0d9de3bcd 138 Gene3D G3DSA:3.30.300.20 44 137 1.9E-34 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_06405 5b05b8e2136855b6d33f54d0d9de3bcd 138 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 136 2.3E-51 T 11-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 UP12_06405 5b05b8e2136855b6d33f54d0d9de3bcd 138 SUPERFAMILY SSF82784 1 136 7.2E-40 T 11-10-2018 IPR036102 OsmC/Ohr superfamily UP12_06405 5b05b8e2136855b6d33f54d0d9de3bcd 138 Gene3D G3DSA:2.20.25.10 3 43 3.6E-17 T 11-10-2018 UP12_06405 5b05b8e2136855b6d33f54d0d9de3bcd 138 Pfam PF02566 OsmC-like protein 40 135 2.0E-20 T 11-10-2018 IPR003718 OsmC/Ohr family UP12_16805 8ce879ba264de22506045e1d9979469c 275 Pfam PF04962 KduI/IolB family 37 267 1.9E-39 T 11-10-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UP12_16805 8ce879ba264de22506045e1d9979469c 275 SUPERFAMILY SSF51182 1 259 1.42E-102 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_16805 8ce879ba264de22506045e1d9979469c 275 Gene3D G3DSA:2.60.120.10 10 260 5.1E-115 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_16805 8ce879ba264de22506045e1d9979469c 275 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 275 55.192 T 11-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UP12_16805 8ce879ba264de22506045e1d9979469c 275 Gene3D G3DSA:2.60.120.520 30 141 5.1E-115 T 11-10-2018 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UP12_16805 8ce879ba264de22506045e1d9979469c 275 PIRSF PIRSF006625 1 275 1.9E-132 T 11-10-2018 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 UP12_15365 dec32683da111c2c2801a8592c779841 1018 Gene3D G3DSA:3.90.1570.50 90 256 1.9E-37 T 11-10-2018 UP12_15365 dec32683da111c2c2801a8592c779841 1018 SMART SM00487 258 471 8.6E-18 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_15365 dec32683da111c2c2801a8592c779841 1018 SUPERFAMILY SSF52540 291 696 1.73E-6 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15365 dec32683da111c2c2801a8592c779841 1018 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 723 982 1.6E-21 T 11-10-2018 IPR022625 Type-1 restriction enzyme R protein, C-terminal UP12_15365 dec32683da111c2c2801a8592c779841 1018 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 205 9.7E-15 T 11-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 UP12_15365 dec32683da111c2c2801a8592c779841 1018 Pfam PF04851 Type III restriction enzyme, res subunit 261 439 3.2E-29 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 UP12_15365 dec32683da111c2c2801a8592c779841 1018 Gene3D G3DSA:3.40.50.300 455 709 1.6E-57 T 11-10-2018 UP12_15365 dec32683da111c2c2801a8592c779841 1018 Gene3D G3DSA:3.40.50.300 261 454 1.6E-53 T 11-10-2018 UP12_15365 dec32683da111c2c2801a8592c779841 1018 SUPERFAMILY SSF52540 261 448 9.84E-28 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15365 dec32683da111c2c2801a8592c779841 1018 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 10 702 8.4E-92 T 11-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 UP12_07795 6297f9c0ce5433153b18b8897d799c62 128 Pfam PF11068 YlqD protein 1 126 5.5E-36 T 11-10-2018 IPR021297 YlqD protein UP12_04170 57a17895c2946df6bc3359ea58aa2c19 114 Gene3D G3DSA:1.10.3730.20 2 107 2.4E-19 T 11-10-2018 UP12_04170 57a17895c2946df6bc3359ea58aa2c19 114 Pfam PF00893 Small Multidrug Resistance protein 4 91 3.3E-17 T 11-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UP12_04170 57a17895c2946df6bc3359ea58aa2c19 114 SUPERFAMILY SSF103481 8 103 1.44E-11 T 11-10-2018 UP12_03570 a60b5fad1b8224e567d1b8c921991e40 493 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 431 1.0E-98 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UP12_03570 a60b5fad1b8224e567d1b8c921991e40 493 Gene3D G3DSA:1.20.1730.10 21 493 1.1E-96 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily UP12_03570 a60b5fad1b8224e567d1b8c921991e40 493 Pfam PF00474 Sodium:solute symporter family 33 431 2.3E-106 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UP12_03570 a60b5fad1b8224e567d1b8c921991e40 493 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 155 180 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site UP12_03570 a60b5fad1b8224e567d1b8c921991e40 493 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 4 487 1.5E-228 T 11-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 UP12_08055 9baddaf57673f0c545b7e6d86b1721dd 185 Gene3D G3DSA:1.10.132.20 12 182 1.8E-70 T 11-10-2018 UP12_08055 9baddaf57673f0c545b7e6d86b1721dd 185 SUPERFAMILY SSF55194 3 185 4.58E-73 T 11-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 UP12_08055 9baddaf57673f0c545b7e6d86b1721dd 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.977 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 UP12_08055 9baddaf57673f0c545b7e6d86b1721dd 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.9E-80 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 UP12_08055 9baddaf57673f0c545b7e6d86b1721dd 185 Gene3D G3DSA:3.30.1360.40 31 105 1.8E-70 T 11-10-2018 UP12_08055 9baddaf57673f0c545b7e6d86b1721dd 185 Pfam PF01765 Ribosome recycling factor 22 183 2.8E-66 T 11-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 UP12_14080 0a06ba656694faed5f974b1cdfdf0b72 380 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 16 368 3.3E-110 T 11-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_14080 0a06ba656694faed5f974b1cdfdf0b72 380 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 328 352 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_14080 0a06ba656694faed5f974b1cdfdf0b72 380 Pfam PF01098 Cell cycle protein 19 370 1.4E-111 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_17830 987316d55e76643bde267dec170c49be 330 SUPERFAMILY SSF51735 1 328 8.0E-101 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17830 987316d55e76643bde267dec170c49be 330 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 2.5E-62 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UP12_17830 987316d55e76643bde267dec170c49be 330 Gene3D G3DSA:3.90.25.10 173 306 1.4E-130 T 11-10-2018 UP12_17830 987316d55e76643bde267dec170c49be 330 Gene3D G3DSA:3.40.50.720 3 252 1.4E-130 T 11-10-2018 UP12_17830 987316d55e76643bde267dec170c49be 330 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 326 1.3E-137 T 11-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 SUPERFAMILY SSF50715 2 185 1.2E-54 T 11-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 Gene3D G3DSA:2.40.240.10 1 93 1.2E-25 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 Gene3D G3DSA:2.170.120.20 96 187 1.2E-27 T 11-10-2018 IPR037121 Ribosomal protein L25, C-terminal UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 4 91 2.0E-31 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 Pfam PF01386 Ribosomal L25p family 4 90 1.5E-21 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 2 181 26.108 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 4 178 2.5E-58 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 UP12_00325 66b7ea56ad1e1922918ce7ad73d2ab8b 208 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 181 2.1E-26 T 11-10-2018 IPR020057 Ribosomal protein L25, beta domain UP12_12900 f03646385c517e1f2ce872cc13ff6e51 177 Pfam PF02674 Colicin V production protein 2 161 3.4E-36 T 11-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 UP12_11960 eb95fa81c3253c17453f9dc8ba1b8b46 474 ProSitePatterns PS00455 Putative AMP-binding domain signature. 139 150 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_11960 eb95fa81c3253c17453f9dc8ba1b8b46 474 SUPERFAMILY SSF56801 2 469 3.01E-96 T 11-10-2018 UP12_11960 eb95fa81c3253c17453f9dc8ba1b8b46 474 Pfam PF13193 AMP-binding enzyme C-terminal domain 385 456 1.0E-12 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_11960 eb95fa81c3253c17453f9dc8ba1b8b46 474 Gene3D G3DSA:3.40.50.12780 1 372 3.3E-68 T 11-10-2018 UP12_11960 eb95fa81c3253c17453f9dc8ba1b8b46 474 Gene3D G3DSA:3.30.300.30 373 472 8.2E-23 T 11-10-2018 UP12_11960 eb95fa81c3253c17453f9dc8ba1b8b46 474 Pfam PF00501 AMP-binding enzyme 2 376 4.3E-52 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_01145 9367dff494965d15c7c07e4ff1b4453e 240 Gene3D G3DSA:3.40.50.300 2 234 2.2E-62 T 11-10-2018 UP12_01145 9367dff494965d15c7c07e4ff1b4453e 240 Pfam PF00005 ABC transporter 20 160 2.3E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_01145 9367dff494965d15c7c07e4ff1b4453e 240 SMART SM00382 28 209 2.7E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_01145 9367dff494965d15c7c07e4ff1b4453e 240 SUPERFAMILY SSF52540 3 222 1.59E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00335 49ead287726097ba40e7db91b9240dfa 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 76 4.8E-39 T 11-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 UP12_00335 49ead287726097ba40e7db91b9240dfa 76 ProDom PD057826 YABK 4 76 2.0E-32 T 11-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 SUPERFAMILY SSF51735 2 167 1.04E-53 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 Gene3D G3DSA:3.90.1820.20 1 433 5.7E-146 T 11-10-2018 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 SUPERFAMILY SSF56327 168 433 5.9E-73 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 4.3E-38 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 72 88 4.3E-38 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 4.3E-38 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 4.3E-38 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 3 18 4.3E-38 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 4.3E-38 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 4.3E-38 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 Pfam PF02056 Family 4 glycosyl hydrolase 3 184 1.9E-68 T 11-10-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 UP12_08995 171c066e6a5c0e6d61d9e866681147f7 443 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 405 1.4E-65 T 11-10-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 UP12_01140 ac9b4b928ac342fe00a933e20f566fd1 129 Gene3D G3DSA:3.30.1330.40 1 128 1.2E-23 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_01140 ac9b4b928ac342fe00a933e20f566fd1 129 SUPERFAMILY SSF55298 2 127 7.7E-26 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_01140 ac9b4b928ac342fe00a933e20f566fd1 129 Pfam PF01042 Endoribonuclease L-PSP 13 125 2.6E-16 T 11-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UP12_11815 3c00d3c89e67e47a032fd0a381c5e150 254 SMART SM00382 26 216 6.9E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_11815 3c00d3c89e67e47a032fd0a381c5e150 254 PIRSF PIRSF039085 1 244 1.1E-100 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UP12_11815 3c00d3c89e67e47a032fd0a381c5e150 254 Gene3D G3DSA:3.40.50.300 1 254 9.3E-77 T 11-10-2018 UP12_11815 3c00d3c89e67e47a032fd0a381c5e150 254 SUPERFAMILY SSF52540 1 238 2.79E-74 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11815 3c00d3c89e67e47a032fd0a381c5e150 254 Pfam PF00005 ABC transporter 17 168 8.3E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_11815 3c00d3c89e67e47a032fd0a381c5e150 254 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_02240 72a8f62a18d20c426abf9db274ae1dcf 88 SMART SM00894 32 87 1.5E-11 T 11-10-2018 IPR008613 Excalibur calcium-binding domain UP12_02240 72a8f62a18d20c426abf9db274ae1dcf 88 Pfam PF05901 Excalibur calcium-binding domain 33 87 4.6E-16 T 11-10-2018 IPR008613 Excalibur calcium-binding domain UP12_03250 d2cab8d4e5aa8f80cbbb3773481bb585 299 Gene3D G3DSA:1.20.1510.10 11 207 1.7E-54 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UP12_03250 d2cab8d4e5aa8f80cbbb3773481bb585 299 Pfam PF01545 Cation efflux family 15 206 9.1E-51 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UP12_03250 d2cab8d4e5aa8f80cbbb3773481bb585 299 SUPERFAMILY SSF161111 8 208 1.96E-54 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UP12_03250 d2cab8d4e5aa8f80cbbb3773481bb585 299 Gene3D G3DSA:3.30.70.1350 212 287 6.5E-16 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 UP12_03250 d2cab8d4e5aa8f80cbbb3773481bb585 299 SUPERFAMILY SSF160240 214 288 1.2E-19 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 UP12_03250 d2cab8d4e5aa8f80cbbb3773481bb585 299 Pfam PF16916 Dimerisation domain of Zinc Transporter 215 287 1.4E-17 T 11-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain UP12_03250 d2cab8d4e5aa8f80cbbb3773481bb585 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 288 8.2E-76 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Pfam PF07724 AAA domain (Cdc48 subfamily) 437 604 3.3E-52 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 206 218 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 SUPERFAMILY SSF52540 73 349 4.87E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 SMART SM00382 111 255 1.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 SMART SM00382 438 611 7.2E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Pfam PF02151 UvrB/uvrC motif 326 359 1.0E-5 T 11-10-2018 IPR001943 UVR domain GO:0005515 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 487 505 6.4E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 516 534 6.4E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 563 6.4E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 442 460 6.4E-37 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 SUPERFAMILY SSF52540 387 690 6.6E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 116 248 6.7E-12 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Gene3D G3DSA:1.10.8.60 256 382 2.2E-37 T 11-10-2018 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Gene3D G3DSA:3.40.50.300 60 253 2.2E-65 T 11-10-2018 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 SMART SM01086 610 697 8.2E-34 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 610 689 1.9E-23 T 11-10-2018 IPR019489 Clp ATPase, C-terminal UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 472 490 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Gene3D G3DSA:1.10.8.60 610 699 8.3E-25 T 11-10-2018 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Gene3D G3DSA:3.40.50.300 391 609 7.3E-83 T 11-10-2018 UP12_06615 ea756f607fb76510d6796b0facbb93d8 700 Gene3D G3DSA:4.10.860.10 319 368 2.2E-37 T 11-10-2018 UP12_11375 6f9afcf9e9e27530dbf9b7b8f9a55e11 286 SUPERFAMILY SSF81345 5 266 1.09E-36 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_11375 6f9afcf9e9e27530dbf9b7b8f9a55e11 286 Pfam PF00950 ABC 3 transport family 8 270 1.5E-64 T 11-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 UP12_11375 6f9afcf9e9e27530dbf9b7b8f9a55e11 286 Gene3D G3DSA:1.10.3470.10 61 280 5.2E-10 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_14250 b849de6532a1bf415ef8552b08815322 121 Gene3D G3DSA:1.10.720.10 63 114 2.7E-21 T 11-10-2018 UP12_14250 b849de6532a1bf415ef8552b08815322 121 SUPERFAMILY SSF160059 1 45 1.83E-16 T 11-10-2018 UP12_14250 b849de6532a1bf415ef8552b08815322 121 Pfam PF14553 YqbF, hypothetical protein domain 7 45 6.3E-17 T 11-10-2018 IPR027926 Uncharacterised protein YqbF domain UP12_14250 b849de6532a1bf415ef8552b08815322 121 Gene3D G3DSA:3.40.5.20 1 45 9.3E-23 T 11-10-2018 IPR036840 YqbF domain superfamily UP12_14250 b849de6532a1bf415ef8552b08815322 121 SUPERFAMILY SSF68912 67 117 1.26E-18 T 11-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily UP12_18050 6cf36441e59e1dcb51845718888212b0 578 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18050 6cf36441e59e1dcb51845718888212b0 578 Pfam PF00664 ABC transporter transmembrane region 16 276 1.7E-31 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_18050 6cf36441e59e1dcb51845718888212b0 578 SUPERFAMILY SSF90123 8 296 1.57E-50 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_18050 6cf36441e59e1dcb51845718888212b0 578 Pfam PF00005 ABC transporter 352 500 3.5E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18050 6cf36441e59e1dcb51845718888212b0 578 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 12 542 1.1E-175 T 11-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 UP12_18050 6cf36441e59e1dcb51845718888212b0 578 Gene3D G3DSA:3.40.50.300 319 573 3.8E-80 T 11-10-2018 UP12_18050 6cf36441e59e1dcb51845718888212b0 578 SMART SM00382 360 546 5.9E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18050 6cf36441e59e1dcb51845718888212b0 578 SUPERFAMILY SSF52540 328 570 5.1E-74 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18050 6cf36441e59e1dcb51845718888212b0 578 Gene3D G3DSA:1.20.1560.10 3 314 1.4E-43 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_05990 5e5993f8087a1bccd16c7c371cce200d 220 PIRSF PIRSF000440 1 212 4.1E-86 T 11-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 UP12_05990 5e5993f8087a1bccd16c7c371cce200d 220 SUPERFAMILY SSF52777 7 209 1.96E-73 T 11-10-2018 UP12_05990 5e5993f8087a1bccd16c7c371cce200d 220 ProDom PD002660 TRANSFERASE CHLORAMPHENICOL ACYLTRANSFERASE ACETYLTRANSFERASE ANTIBIOTIC RESISTANCE PLASMID CAT O-ACETYLTRANSFERASE DIRECT 11 197 4.0E-105 T 11-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 UP12_05990 5e5993f8087a1bccd16c7c371cce200d 220 ProSitePatterns PS00100 Chloramphenicol acetyltransferase active site. 184 194 - T 11-10-2018 IPR018372 Chloramphenicol acetyltransferase, active site GO:0008811 UP12_05990 5e5993f8087a1bccd16c7c371cce200d 220 SMART SM01059 1 203 4.0E-113 T 11-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 UP12_05990 5e5993f8087a1bccd16c7c371cce200d 220 Pfam PF00302 Chloramphenicol acetyltransferase 2 203 1.1E-94 T 11-10-2018 IPR001707 Chloramphenicol acetyltransferase GO:0008811 UP12_05990 5e5993f8087a1bccd16c7c371cce200d 220 Gene3D G3DSA:3.30.559.10 3 206 1.1E-66 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_19640 2cface9702c1e312ab4f305e56c44746 692 Gene3D G3DSA:3.30.930.30 2 222 5.0E-66 T 11-10-2018 UP12_19640 2cface9702c1e312ab4f305e56c44746 692 Pfam PF03389 MobA/MobL family 22 244 1.3E-78 T 11-10-2018 IPR005053 MobA/MobL protein UP12_19640 2cface9702c1e312ab4f305e56c44746 692 Gene3D G3DSA:1.20.58.1730 264 423 1.7E-12 T 11-10-2018 UP12_16655 eeaca752d27b35c09d2d236d17e65785 394 Gene3D G3DSA:3.40.50.2000 209 364 9.5E-32 T 11-10-2018 UP12_16655 eeaca752d27b35c09d2d236d17e65785 394 Gene3D G3DSA:3.40.50.2000 1 208 4.8E-24 T 11-10-2018 UP12_16655 eeaca752d27b35c09d2d236d17e65785 394 SUPERFAMILY SSF53756 1 387 5.83E-63 T 11-10-2018 UP12_16655 eeaca752d27b35c09d2d236d17e65785 394 Pfam PF00534 Glycosyl transferases group 1 207 352 1.9E-27 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 UP12_16655 eeaca752d27b35c09d2d236d17e65785 394 Pfam PF13579 Glycosyl transferase 4-like domain 26 179 4.5E-14 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UP12_12810 9abd7220adec46a02c95eb76fe89d0bb 153 Pfam PF03061 Thioesterase superfamily 34 119 8.4E-14 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 UP12_12810 9abd7220adec46a02c95eb76fe89d0bb 153 SUPERFAMILY SSF54637 14 149 2.03E-34 T 11-10-2018 IPR029069 HotDog domain superfamily UP12_12810 9abd7220adec46a02c95eb76fe89d0bb 153 Gene3D G3DSA:3.10.129.10 8 150 6.6E-34 T 11-10-2018 UP12_17110 6b94d3dbcf5df63f76e9791be64159ff 398 SMART SM00833 260 375 8.6E-47 T 11-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UP12_17110 6b94d3dbcf5df63f76e9791be64159ff 398 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 211 5.5E-59 T 11-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain UP12_17110 6b94d3dbcf5df63f76e9791be64159ff 398 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 260 375 3.7E-26 T 11-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal UP12_17110 6b94d3dbcf5df63f76e9791be64159ff 398 SUPERFAMILY SSF52540 3 308 3.19E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17110 6b94d3dbcf5df63f76e9791be64159ff 398 Gene3D G3DSA:3.40.50.300 2 230 9.5E-73 T 11-10-2018 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 Gene3D G3DSA:3.30.360.10 136 343 5.4E-149 T 11-10-2018 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 8.2E-24 T 11-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 SUPERFAMILY SSF51735 2 158 1.53E-33 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 SUPERFAMILY SSF55347 137 302 5.75E-53 T 11-10-2018 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 SUPERFAMILY SSF55021 349 422 1.13E-12 T 11-10-2018 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 Pfam PF00742 Homoserine dehydrogenase 137 315 9.5E-66 T 11-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 Gene3D G3DSA:3.40.50.720 4 336 5.4E-149 T 11-10-2018 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 Gene3D G3DSA:3.30.70.260 344 418 5.4E-149 T 11-10-2018 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 PIRSF PIRSF000098 1 430 1.5E-172 T 11-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 11-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 UP12_15190 6583ed0db0763d4b9f27ddc342e68775 433 Pfam PF01842 ACT domain 351 416 2.0E-14 T 11-10-2018 IPR002912 ACT domain UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 27.384 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 11-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 2.0E-17 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 SUPERFAMILY SSF110324 10 91 1.43E-32 T 11-10-2018 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 Gene3D G3DSA:2.40.50.100 28 93 3.1E-26 T 11-10-2018 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 PRINTS PR00063 Ribosomal protein L27 signature 12 36 5.1E-39 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 PRINTS PR00063 Ribosomal protein L27 signature 62 86 5.1E-39 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 PRINTS PR00063 Ribosomal protein L27 signature 37 61 5.1E-39 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 Pfam PF01016 Ribosomal L27 protein 10 89 3.6E-35 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_12240 f3ce4b96658a0cb7b66eee5e385954e0 94 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 3.4E-41 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_13510 3d1c53ba13b4ea662f62d6ba45d38075 309 SUPERFAMILY SSF111331 2 308 6.54E-60 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UP12_13510 3d1c53ba13b4ea662f62d6ba45d38075 309 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 126 2.0E-26 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UP12_13510 3d1c53ba13b4ea662f62d6ba45d38075 309 Gene3D G3DSA:2.60.200.40 136 300 2.5E-30 T 11-10-2018 UP12_13510 3d1c53ba13b4ea662f62d6ba45d38075 309 Gene3D G3DSA:3.40.50.10330 1 133 1.2E-28 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UP12_13510 3d1c53ba13b4ea662f62d6ba45d38075 309 SMART SM00046 3 145 0.0057 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UP12_13510 3d1c53ba13b4ea662f62d6ba45d38075 309 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 308 8.9E-71 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase UP12_09025 e938d4a30556877e72593d58e6c0f827 420 Pfam PF03611 PTS system sugar-specific permease component 8 403 3.5E-140 T 11-10-2018 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 SMART SM00382 119 297 3.0E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 9.0E-81 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 66.01 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 Gene3D G3DSA:1.20.120.140 20 318 1.8E-114 T 11-10-2018 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 Pfam PF02881 SRP54-type protein, helical bundle domain 34 99 9.1E-15 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 SUPERFAMILY SSF52540 121 320 1.67E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 SUPERFAMILY SSF47364 18 96 3.4E-21 T 11-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 2.2E-119 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 Gene3D G3DSA:3.40.50.300 112 309 1.8E-114 T 11-10-2018 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 SMART SM00962 120 321 5.6E-121 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_07770 a430f95a6bcb0531f97cef41c72b3b54 328 SMART SM00963 22 103 3.9E-26 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 SUPERFAMILY SSF51905 5 321 1.94E-41 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 Gene3D G3DSA:3.50.50.60 131 249 5.4E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 1.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 1.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 119 127 1.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 244 265 1.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 290 7.3E-107 T 11-10-2018 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 Gene3D G3DSA:3.50.50.60 7 294 5.4E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 319 3.1E-141 T 11-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 7.0E-13 T 11-10-2018 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 7.0E-13 T 11-10-2018 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 7.0E-13 T 11-10-2018 UP12_10320 40dec51e528fb8a4f28cf5071a2af490 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 7.0E-13 T 11-10-2018 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 421 7.9E-143 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 SUPERFAMILY SSF52374 2 325 2.11E-105 T 11-10-2018 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 Gene3D G3DSA:3.10.290.10 328 422 4.9E-34 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 SMART SM00363 356 417 5.3E-12 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 SUPERFAMILY SSF55174 323 421 9.55E-25 T 11-10-2018 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 Gene3D G3DSA:1.10.240.10 225 327 1.9E-41 T 11-10-2018 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 50 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 Pfam PF01479 S4 domain 357 402 5.3E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 2 421 46.031 T 11-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 Gene3D G3DSA:3.40.50.620 1 224 7.5E-87 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_13390 f0bdeb96f44099887c5419f473007b58 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 183 205 5.2E-31 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 218 230 5.2E-31 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 162 177 5.2E-31 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 5.2E-31 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 UP12_13390 f0bdeb96f44099887c5419f473007b58 422 Pfam PF00579 tRNA synthetases class I (W and Y) 29 326 1.4E-87 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.2E-8 T 11-10-2018 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 1.2E-8 T 11-10-2018 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 SUPERFAMILY SSF56425 231 353 3.89E-31 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 SUPERFAMILY SSF46977 443 579 1.96E-45 T 11-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 Gene3D G3DSA:3.50.50.60 6 403 3.2E-124 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_12820 8eb040d13daf044277253e8d4be7e242 586 Gene3D G3DSA:3.90.700.10 258 367 3.2E-124 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 579 2.1E-42 T 11-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 PIRSF PIRSF000171 1 240 8.2E-21 T 11-10-2018 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 PIRSF PIRSF000171 343 576 2.2E-16 T 11-10-2018 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.2E-6 T 11-10-2018 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 1.2E-6 T 11-10-2018 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 Gene3D G3DSA:1.20.58.100 422 539 7.3E-35 T 11-10-2018 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 11-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 579 5.2E-287 T 11-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 UP12_12820 8eb040d13daf044277253e8d4be7e242 586 SUPERFAMILY SSF51905 6 424 2.78E-64 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_12820 8eb040d13daf044277253e8d4be7e242 586 Pfam PF00890 FAD binding domain 6 392 2.6E-88 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 UP12_16595 2b6968072666a19a5aa715c84c25939a 280 SUPERFAMILY SSF82549 1 279 2.88E-98 T 11-10-2018 UP12_16595 2b6968072666a19a5aa715c84c25939a 280 Gene3D G3DSA:3.30.1180.10 153 280 4.2E-46 T 11-10-2018 UP12_16595 2b6968072666a19a5aa715c84c25939a 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 3.1E-106 T 11-10-2018 IPR003797 DegV UP12_16595 2b6968072666a19a5aa715c84c25939a 280 Gene3D G3DSA:3.40.50.10170 1 151 7.8E-58 T 11-10-2018 UP12_16595 2b6968072666a19a5aa715c84c25939a 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 278 1.4E-102 T 11-10-2018 IPR003797 DegV UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 PIRSF PIRSF001456 1 384 2.7E-134 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 Pfam PF01264 Chorismate synthase 1 364 4.5E-126 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 TIGRFAM TIGR00033 aroC: chorismate synthase 1 369 2.6E-130 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 Hamap MF_00300 Chorismate synthase [aroC]. 1 372 36.899 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 ProSitePatterns PS00788 Chorismate synthase signature 2. 131 147 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 339 355 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 SUPERFAMILY SSF103263 1 388 4.71E-151 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_10195 47ed98c1853ee1012fff1f8d733f3659 390 Gene3D G3DSA:3.60.150.10 1 389 1.6E-157 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 UP12_08245 cf77786fd15cec6441ebe2d5f589b640 426 Gene3D G3DSA:3.30.830.10 239 425 9.5E-42 T 11-10-2018 UP12_08245 cf77786fd15cec6441ebe2d5f589b640 426 SUPERFAMILY SSF63411 6 224 1.6E-26 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UP12_08245 cf77786fd15cec6441ebe2d5f589b640 426 Pfam PF05193 Peptidase M16 inactive domain 185 357 9.6E-28 T 11-10-2018 IPR007863 Peptidase M16, C-terminal UP12_08245 cf77786fd15cec6441ebe2d5f589b640 426 SUPERFAMILY SSF63411 247 414 3.0E-30 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UP12_08245 cf77786fd15cec6441ebe2d5f589b640 426 Gene3D G3DSA:3.30.830.10 6 234 1.3E-63 T 11-10-2018 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 Pfam PF06463 Molybdenum Cofactor Synthesis C 191 316 3.3E-37 T 11-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 Pfam PF13353 4Fe-4S single cluster domain 21 114 6.3E-7 T 11-10-2018 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 19 30 - T 11-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 4 335 41.091 T 11-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 5 335 2.1E-118 T 11-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 Pfam PF04055 Radical SAM superfamily 17 181 1.8E-34 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 SMART SM00729 13 222 2.1E-18 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 Gene3D G3DSA:3.20.20.70 1 335 3.6E-107 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_17120 6d26d6d602d20af38567a51390bb0412 335 SUPERFAMILY SSF102114 5 308 1.07E-81 T 11-10-2018 UP12_05665 cf687c483631c3a36928804c91cde76a 544 PIRSF PIRSF002741 4 544 2.8E-160 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 UP12_05665 cf687c483631c3a36928804c91cde76a 544 Gene3D G3DSA:3.10.105.10 289 512 4.1E-186 T 11-10-2018 UP12_05665 cf687c483631c3a36928804c91cde76a 544 SUPERFAMILY SSF53850 42 542 3.98E-140 T 11-10-2018 UP12_05665 cf687c483631c3a36928804c91cde76a 544 Gene3D G3DSA:3.40.190.10 55 526 4.1E-186 T 11-10-2018 UP12_05665 cf687c483631c3a36928804c91cde76a 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 90 457 9.6E-94 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain UP12_05665 cf687c483631c3a36928804c91cde76a 544 Gene3D G3DSA:3.90.76.10 77 196 4.1E-186 T 11-10-2018 UP12_02255 145c48f451f2a270f86b783882999c92 405 Pfam PF01566 Natural resistance-associated macrophage protein 52 372 4.3E-19 T 11-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 UP12_11245 f69730f4aa91b57fdadff1860f7af649 639 PIRSF PIRSF005091 1 620 1.1E-197 T 11-10-2018 IPR012160 Lipoteichoic acid synthase-like UP12_11245 f69730f4aa91b57fdadff1860f7af649 639 Gene3D G3DSA:3.40.720.10 238 546 1.6E-74 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_11245 f69730f4aa91b57fdadff1860f7af649 639 Pfam PF00884 Sulfatase 245 536 9.0E-31 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 UP12_11245 f69730f4aa91b57fdadff1860f7af649 639 SUPERFAMILY SSF53649 243 619 1.61E-69 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 PRINTS PR01874 DNA repair protein radA signature 322 345 4.1E-94 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 PRINTS PR01874 DNA repair protein radA signature 213 241 4.1E-94 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 PRINTS PR01874 DNA repair protein radA signature 248 274 4.1E-94 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 PRINTS PR01874 DNA repair protein radA signature 10 34 4.1E-94 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 PRINTS PR01874 DNA repair protein radA signature 82 110 4.1E-94 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 PRINTS PR01874 DNA repair protein radA signature 124 141 4.1E-94 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 PRINTS PR01874 DNA repair protein radA signature 174 198 4.1E-94 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 Gene3D G3DSA:3.40.50.300 64 286 1.3E-43 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 Pfam PF13481 AAA domain 67 222 1.9E-15 T 11-10-2018 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 SUPERFAMILY SSF52540 68 293 5.01E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 Gene3D G3DSA:3.30.230.10 287 457 4.0E-20 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 SMART SM00382 90 244 3.5E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 452 4.3E-223 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 Hamap MF_01498 DNA repair protein RadA [radA]. 21 456 45.172 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 SUPERFAMILY SSF54211 255 456 2.62E-42 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_00585 6101e9753b48e2413cffb6b7bd37bd49 459 Pfam PF13541 Subunit ChlI of Mg-chelatase 366 430 8.3E-10 T 11-10-2018 UP12_07040 5b8733661d8a358904e55113c65f41bc 259 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 250 8.2E-61 T 11-10-2018 UP12_07040 5b8733661d8a358904e55113c65f41bc 259 Gene3D G3DSA:3.40.50.1000 4 247 8.9E-82 T 11-10-2018 IPR023214 HAD superfamily UP12_07040 5b8733661d8a358904e55113c65f41bc 259 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 224 3.0E-26 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_07040 5b8733661d8a358904e55113c65f41bc 259 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 11-10-2018 UP12_07040 5b8733661d8a358904e55113c65f41bc 259 SUPERFAMILY SSF56784 1 256 2.96E-69 T 11-10-2018 IPR036412 HAD-like superfamily UP12_07040 5b8733661d8a358904e55113c65f41bc 259 Gene3D G3DSA:3.30.1240.10 81 180 8.9E-82 T 11-10-2018 UP12_07040 5b8733661d8a358904e55113c65f41bc 259 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 250 2.6E-63 T 11-10-2018 IPR000150 Cof family GO:0016787 UP12_08330 20e3ac7b2b9a390bf77f78574a85056f 392 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 22 380 7.1E-135 T 11-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 UP12_08330 20e3ac7b2b9a390bf77f78574a85056f 392 Gene3D G3DSA:3.90.1150.10 35 382 2.5E-145 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_08330 20e3ac7b2b9a390bf77f78574a85056f 392 Pfam PF00155 Aminotransferase class I and II 41 380 6.6E-65 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_08330 20e3ac7b2b9a390bf77f78574a85056f 392 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 391 1.7E-189 T 11-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type UP12_08330 20e3ac7b2b9a390bf77f78574a85056f 392 Gene3D G3DSA:3.40.640.10 55 289 2.5E-145 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_08330 20e3ac7b2b9a390bf77f78574a85056f 392 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 236 245 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 UP12_08330 20e3ac7b2b9a390bf77f78574a85056f 392 SUPERFAMILY SSF53383 2 389 4.76E-112 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_06500 6433a1680fc584c0affddc01484d05fd 251 TIGRFAM TIGR02895 spore_sigI: RNA polymerase sigma-I factor 24 245 1.8E-85 T 11-10-2018 IPR014244 RNA polymerase sigma-I type UP12_06500 6433a1680fc584c0affddc01484d05fd 251 SUPERFAMILY SSF88946 25 104 9.58E-19 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_06500 6433a1680fc584c0affddc01484d05fd 251 Hamap MF_02064 RNA polymerase sigma factor SigI [sigI]. 17 247 28.96 T 11-10-2018 IPR014244 RNA polymerase sigma-I type UP12_06500 6433a1680fc584c0affddc01484d05fd 251 Gene3D G3DSA:1.10.1740.10 22 103 6.8E-10 T 11-10-2018 UP12_06500 6433a1680fc584c0affddc01484d05fd 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 229 3.7E-14 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_06500 6433a1680fc584c0affddc01484d05fd 251 PIRSF PIRSF038953 8 251 1.2E-67 T 11-10-2018 IPR014244 RNA polymerase sigma-I type UP12_06500 6433a1680fc584c0affddc01484d05fd 251 Pfam PF04542 Sigma-70 region 2 36 106 1.3E-11 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_18525 242783b5992d38ad1e73b9a7f3a69798 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 269 6.2E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_18525 242783b5992d38ad1e73b9a7f3a69798 280 Gene3D G3DSA:1.10.3720.10 1 267 8.5E-62 T 11-10-2018 IPR035906 MetI-like superfamily UP12_18525 242783b5992d38ad1e73b9a7f3a69798 280 SUPERFAMILY SSF161098 6 280 6.67E-68 T 11-10-2018 IPR035906 MetI-like superfamily UP12_13880 116b09ee07f855560d0ce078ff311913 73 Pfam PF07561 Domain of Unknown Function (DUF1540) 26 68 7.9E-16 T 11-10-2018 IPR011437 Domain of unknown function DUF1540 UP12_09895 cc3a51ef1e4aef2f38167a7d4f1b80e3 1199 Pfam PF00350 Dynamin family 47 201 1.4E-24 T 11-10-2018 IPR022812 Dynamin superfamily UP12_09895 cc3a51ef1e4aef2f38167a7d4f1b80e3 1199 Pfam PF00350 Dynamin family 621 845 1.2E-38 T 11-10-2018 IPR022812 Dynamin superfamily UP12_09895 cc3a51ef1e4aef2f38167a7d4f1b80e3 1199 SUPERFAMILY SSF52540 604 885 3.72E-29 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09895 cc3a51ef1e4aef2f38167a7d4f1b80e3 1199 Gene3D G3DSA:3.40.50.300 47 275 3.7E-38 T 11-10-2018 UP12_09895 cc3a51ef1e4aef2f38167a7d4f1b80e3 1199 SUPERFAMILY SSF52540 25 288 4.12E-28 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07410 671959d4941db7407df892de718f11ff 440 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 206 219 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 UP12_07410 671959d4941db7407df892de718f11ff 440 SUPERFAMILY SSF53067 197 368 2.49E-43 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 Pfam PF14450 Cell division protein FtsA 205 366 4.8E-24 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 Gene3D G3DSA:3.30.420.40 195 349 1.7E-111 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 Gene3D G3DSA:3.30.420.40 10 363 1.7E-111 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 SMART SM00842 7 194 1.8E-91 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 UP12_07410 671959d4941db7407df892de718f11ff 440 Gene3D G3DSA:3.30.1490.110 83 167 1.7E-111 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 439 29.671 T 11-10-2018 IPR020823 Cell division protein FtsA UP12_07410 671959d4941db7407df892de718f11ff 440 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 2.3E-130 T 11-10-2018 IPR020823 Cell division protein FtsA UP12_07410 671959d4941db7407df892de718f11ff 440 Gene3D G3DSA:3.90.640.10 233 298 1.7E-111 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 Pfam PF14450 Cell division protein FtsA 9 187 5.9E-9 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 SUPERFAMILY SSF53067 6 195 4.49E-57 T 11-10-2018 UP12_07410 671959d4941db7407df892de718f11ff 440 PIRSF PIRSF003101 1 439 6.4E-149 T 11-10-2018 IPR020823 Cell division protein FtsA UP12_07410 671959d4941db7407df892de718f11ff 440 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 7.3E-25 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 UP12_14575 3b148196217e795ffe46278bb8a69a78 222 Pfam PF01476 LysM domain 164 221 4.0E-19 T 11-10-2018 IPR018392 LysM domain UP12_14575 3b148196217e795ffe46278bb8a69a78 222 Gene3D G3DSA:3.10.350.10 162 220 4.8E-13 T 11-10-2018 IPR036779 LysM domain superfamily UP12_14575 3b148196217e795ffe46278bb8a69a78 222 SMART SM00257 163 221 2.9E-8 T 11-10-2018 IPR018392 LysM domain UP12_14575 3b148196217e795ffe46278bb8a69a78 222 SUPERFAMILY SSF54106 161 221 2.49E-7 T 11-10-2018 UP12_07845 1bf2c56a376d47254fa02dcce6b27567 300 Pfam PF02481 DNA recombination-mediator protein A 75 280 1.9E-75 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 UP12_07845 1bf2c56a376d47254fa02dcce6b27567 300 SUPERFAMILY SSF102405 83 289 5.65E-33 T 11-10-2018 UP12_07845 1bf2c56a376d47254fa02dcce6b27567 300 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 289 7.6E-79 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 UP12_07845 1bf2c56a376d47254fa02dcce6b27567 300 Gene3D G3DSA:3.40.50.450 22 295 5.1E-92 T 11-10-2018 UP12_04655 15ed346c56f4a9ad8391d072336d4e6e 157 SUPERFAMILY SSF75217 3 155 4.25E-45 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases UP12_04655 15ed346c56f4a9ad8391d072336d4e6e 157 Gene3D G3DSA:3.40.1280.10 2 157 5.3E-67 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UP12_04655 15ed346c56f4a9ad8391d072336d4e6e 157 Pfam PF00588 SpoU rRNA Methylase family 3 145 4.1E-33 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 UP12_04655 15ed346c56f4a9ad8391d072336d4e6e 157 PIRSF PIRSF029256 2 157 8.8E-68 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 UP12_04655 15ed346c56f4a9ad8391d072336d4e6e 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.223 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 UP12_04655 15ed346c56f4a9ad8391d072336d4e6e 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 3 156 4.9E-70 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 UP12_17065 e25dc8adf6c57b1581649823610aaf46 298 Pfam PF01551 Peptidase family M23 118 215 4.3E-24 T 11-10-2018 IPR016047 Peptidase M23 UP12_17065 e25dc8adf6c57b1581649823610aaf46 298 Gene3D G3DSA:2.70.70.10 74 231 6.0E-53 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_17065 e25dc8adf6c57b1581649823610aaf46 298 SUPERFAMILY SSF51261 59 219 1.73E-27 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_13505 dbf5342265c624fac39e3312dc78fd0c 270 Gene3D G3DSA:3.90.1200.10 83 267 8.2E-25 T 11-10-2018 UP12_13505 dbf5342265c624fac39e3312dc78fd0c 270 Pfam PF01636 Phosphotransferase enzyme family 21 232 9.6E-23 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase UP12_13505 dbf5342265c624fac39e3312dc78fd0c 270 SUPERFAMILY SSF56112 6 234 7.62E-33 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 SUPERFAMILY SSF51338 1 427 2.65E-28 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 SUPERFAMILY SSF51556 54 368 8.35E-110 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 302 313 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 423 45.041 T 11-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 424 8.6E-161 T 11-10-2018 UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 Gene3D G3DSA:2.30.40.10 7 419 1.9E-152 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 Pfam PF01979 Amidohydrolase family 50 420 7.8E-55 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UP12_07545 ed3fb414e1828a74dfbbe5b540e2215b 428 Gene3D G3DSA:3.20.20.140 54 366 1.9E-152 T 11-10-2018 UP12_00100 f43758184345e14a6a0990a198a52a47 276 Gene3D G3DSA:1.10.287.950 101 276 7.5E-44 T 11-10-2018 UP12_00100 f43758184345e14a6a0990a198a52a47 276 SUPERFAMILY SSF58104 109 272 4.71E-45 T 11-10-2018 UP12_00100 f43758184345e14a6a0990a198a52a47 276 SMART SM00283 90 272 4.8E-14 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_00100 f43758184345e14a6a0990a198a52a47 276 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 148 266 6.1E-32 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_18530 77da860b54db8bf99c65546c8f361715 402 Gene3D G3DSA:3.20.20.80 21 402 8.1E-153 T 11-10-2018 UP12_18530 77da860b54db8bf99c65546c8f361715 402 Pfam PF07745 Glycosyl hydrolase family 53 41 397 1.1E-125 T 11-10-2018 IPR011683 Glycosyl hydrolase family 53 GO:0015926 UP12_18530 77da860b54db8bf99c65546c8f361715 402 SUPERFAMILY SSF51445 38 401 2.12E-103 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_12160 fc62fd4f7fb2d6ed5fcf9d1d066ff907 170 Pfam PF08977 Bypass of Forespore C, N terminal 37 87 1.3E-22 T 11-10-2018 IPR015071 Bypass-of-forespore C, N-terminal UP12_12160 fc62fd4f7fb2d6ed5fcf9d1d066ff907 170 Gene3D G3DSA:3.10.20.420 35 88 3.1E-18 T 11-10-2018 IPR038118 Bypass-of-forespore C, N-terminal domain superfamily UP12_12160 fc62fd4f7fb2d6ed5fcf9d1d066ff907 170 Pfam PF08955 BofC C-terminal domain 89 162 3.9E-28 T 11-10-2018 IPR015050 Bypass of forespore C, C-terminal UP12_12160 fc62fd4f7fb2d6ed5fcf9d1d066ff907 170 Gene3D G3DSA:3.30.70.1740 89 166 9.3E-28 T 11-10-2018 IPR038117 Bypass of forespore C, C-terminal domain superfamily UP12_12275 054bf1b5e6889248f0c977ba15389a7f 172 Pfam PF04093 rod shape-determining protein MreD 3 162 2.1E-34 T 11-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 UP12_12275 054bf1b5e6889248f0c977ba15389a7f 172 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 8 159 1.5E-24 T 11-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 UP12_00625 5b24744770cfaa9f153ffe2b3a491623 143 SMART SM00535 1 134 4.0E-15 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UP12_00625 5b24744770cfaa9f153ffe2b3a491623 143 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 7 133 29.828 T 11-10-2018 IPR008226 Mini-ribonuclease 3 family UP12_00625 5b24744770cfaa9f153ffe2b3a491623 143 SUPERFAMILY SSF69065 9 130 1.92E-42 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 UP12_00625 5b24744770cfaa9f153ffe2b3a491623 143 PIRSF PIRSF005520 1 139 1.0E-53 T 11-10-2018 IPR008226 Mini-ribonuclease 3 family UP12_00625 5b24744770cfaa9f153ffe2b3a491623 143 Pfam PF00636 Ribonuclease III domain 17 116 1.3E-17 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 UP12_00625 5b24744770cfaa9f153ffe2b3a491623 143 Gene3D G3DSA:1.10.1520.10 4 143 1.1E-52 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 UP12_00240 d87710d1ba5221b26528af56dcb2e190 98 SUPERFAMILY SSF82771 6 77 3.01E-15 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UP12_00240 d87710d1ba5221b26528af56dcb2e190 98 Pfam PF01541 GIY-YIG catalytic domain 6 75 5.4E-18 T 11-10-2018 IPR000305 GIY-YIG endonuclease UP12_00240 d87710d1ba5221b26528af56dcb2e190 98 SMART SM00465 5 83 9.9E-5 T 11-10-2018 IPR000305 GIY-YIG endonuclease UP12_00240 d87710d1ba5221b26528af56dcb2e190 98 Gene3D G3DSA:3.40.1440.10 1 97 1.4E-33 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 UP12_06470 1a26d0b6377cfdc1025642079b5af10c 109 Gene3D G3DSA:1.10.1660.10 6 88 1.1E-22 T 11-10-2018 UP12_06470 1a26d0b6377cfdc1025642079b5af10c 109 SUPERFAMILY SSF46955 15 102 1.6E-17 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_06470 1a26d0b6377cfdc1025642079b5af10c 109 SMART SM00422 14 82 7.1E-23 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_06470 1a26d0b6377cfdc1025642079b5af10c 109 Pfam PF13411 MerR HTH family regulatory protein 15 76 1.1E-14 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_06470 1a26d0b6377cfdc1025642079b5af10c 109 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 26 1.5E-5 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_06470 1a26d0b6377cfdc1025642079b5af10c 109 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 49 69 1.5E-5 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_06470 1a26d0b6377cfdc1025642079b5af10c 109 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 39 1.5E-5 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_14850 b74645c81517894df904bc3e4aa903a7 130 Gene3D G3DSA:2.30.30.430 1 125 1.8E-49 T 11-10-2018 IPR038080 Kinase associated protein B superfamily UP12_14850 b74645c81517894df904bc3e4aa903a7 130 Pfam PF08810 Kinase associated protein B 14 125 3.8E-48 T 11-10-2018 IPR014916 Kinase associated protein B UP12_14850 b74645c81517894df904bc3e4aa903a7 130 SUPERFAMILY SSF141251 4 125 6.15E-52 T 11-10-2018 IPR038080 Kinase associated protein B superfamily UP12_14850 b74645c81517894df904bc3e4aa903a7 130 SMART SM01298 14 126 9.5E-74 T 11-10-2018 IPR014916 Kinase associated protein B UP12_02085 8418abcfa57e2ba40aa5fa8f62841fd4 463 Pfam PF00324 Amino acid permease 5 446 2.3E-119 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_02085 8418abcfa57e2ba40aa5fa8f62841fd4 463 ProSitePatterns PS00218 Amino acid permeases signature. 30 61 - T 11-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 UP12_02085 8418abcfa57e2ba40aa5fa8f62841fd4 463 Gene3D G3DSA:1.20.1740.10 1 458 5.0E-71 T 11-10-2018 UP12_02085 8418abcfa57e2ba40aa5fa8f62841fd4 463 PIRSF PIRSF006060 1 461 5.8E-86 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 7.5E-40 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 SMART SM00471 46 158 2.1E-8 T 11-10-2018 IPR003607 HD/PDEase domain UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 SUPERFAMILY SSF81271 384 456 2.62E-22 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Gene3D G3DSA:3.30.70.260 657 736 4.5E-18 T 11-10-2018 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 SUPERFAMILY SSF81301 197 373 2.78E-67 T 11-10-2018 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 733 2.0E-258 T 11-10-2018 IPR004811 RelA/SpoT family GO:0015969 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Gene3D G3DSA:3.30.460.10 198 329 4.2E-54 T 11-10-2018 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 SUPERFAMILY SSF109604 12 196 2.51E-75 T 11-10-2018 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 SMART SM00954 240 350 2.1E-70 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Pfam PF13291 ACT domain 657 733 5.7E-21 T 11-10-2018 IPR002912 ACT domain UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 SUPERFAMILY SSF55021 659 735 3.41E-12 T 11-10-2018 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Gene3D G3DSA:1.10.3210.10 1 196 1.5E-87 T 11-10-2018 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Pfam PF02824 TGS domain 397 456 1.1E-22 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Gene3D G3DSA:3.10.20.30 390 462 8.2E-32 T 11-10-2018 IPR012675 Beta-grasp domain superfamily UP12_12080 e9bad30786cc4ed5e35461661c15c29f 736 Pfam PF13328 HD domain 31 180 9.8E-52 T 11-10-2018 IPR003607 HD/PDEase domain UP12_02930 d8045a3dcbd2138bdefbda0c09968e0b 299 SUPERFAMILY SSF53474 4 274 5.18E-42 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02930 d8045a3dcbd2138bdefbda0c09968e0b 299 Gene3D G3DSA:3.40.50.1820 2 279 3.6E-46 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02930 d8045a3dcbd2138bdefbda0c09968e0b 299 Pfam PF00561 alpha/beta hydrolase fold 24 273 4.1E-19 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_02930 d8045a3dcbd2138bdefbda0c09968e0b 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 4.3E-5 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_02930 d8045a3dcbd2138bdefbda0c09968e0b 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 4.3E-5 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_02930 d8045a3dcbd2138bdefbda0c09968e0b 299 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 4.3E-5 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_10385 b7b1d046e3418b07b4084bd4ceb78580 369 ProDom PD136539 TRANSCRIPTION SIGMA-X NEGATIVE ACTIVITY RSIX REPRESSOR MEMBRANE EFFECTOR REGULATION REGULATOR 5 362 1.0E-61 T 11-10-2018 UP12_03010 09d9936bf92d38bb1fc1c645c39d5f2f 207 Pfam PF00881 Nitroreductase family 9 185 6.7E-26 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UP12_03010 09d9936bf92d38bb1fc1c645c39d5f2f 207 SUPERFAMILY SSF55469 4 206 1.96E-46 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_03010 09d9936bf92d38bb1fc1c645c39d5f2f 207 Gene3D G3DSA:3.40.109.10 2 207 1.0E-56 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_11640 0a1b10badec466045eb2ed7e9a39d1a5 118 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 7.3E-25 T 11-10-2018 UP12_11640 0a1b10badec466045eb2ed7e9a39d1a5 118 SUPERFAMILY SSF81301 1 112 4.41E-39 T 11-10-2018 UP12_11640 0a1b10badec466045eb2ed7e9a39d1a5 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 3.2E-35 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS UP12_11640 0a1b10badec466045eb2ed7e9a39d1a5 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.585 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS UP12_11640 0a1b10badec466045eb2ed7e9a39d1a5 118 Gene3D G3DSA:3.30.460.10 1 108 1.4E-37 T 11-10-2018 UP12_08695 7c89e21f62163255050d967cca5a45aa 76 Hamap MF_01103 UPF0291 protein . 2 60 16.491 T 11-10-2018 IPR009242 Protein of unknown function DUF896 UP12_08695 7c89e21f62163255050d967cca5a45aa 76 SUPERFAMILY SSF158221 1 42 6.02E-14 T 11-10-2018 UP12_08695 7c89e21f62163255050d967cca5a45aa 76 Gene3D G3DSA:1.10.287.540 1 56 3.2E-23 T 11-10-2018 UP12_08695 7c89e21f62163255050d967cca5a45aa 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 6 68 2.1E-31 T 11-10-2018 IPR009242 Protein of unknown function DUF896 UP12_06175 c7ba66dd985d52df0c785035a79bf7d0 205 Gene3D G3DSA:1.20.58.220 9 205 2.6E-55 T 11-10-2018 IPR038078 PhoU-like domain superfamily UP12_06175 c7ba66dd985d52df0c785035a79bf7d0 205 Pfam PF01865 Protein of unknown function DUF47 8 202 2.1E-24 T 11-10-2018 IPR018445 Putative phosphate transport regulator UP12_06175 c7ba66dd985d52df0c785035a79bf7d0 205 SUPERFAMILY SSF109755 14 196 3.27E-6 T 11-10-2018 UP12_06560 93b73aa2d3914a58aa9da80c9c9d3fdd 397 PIRSF PIRSF031134 3 396 2.7E-151 T 11-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 UP12_06560 93b73aa2d3914a58aa9da80c9c9d3fdd 397 Gene3D G3DSA:3.90.1200.10 119 397 1.3E-102 T 11-10-2018 UP12_06560 93b73aa2d3914a58aa9da80c9c9d3fdd 397 Gene3D G3DSA:3.30.200.20 2 118 1.9E-44 T 11-10-2018 UP12_06560 93b73aa2d3914a58aa9da80c9c9d3fdd 397 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 36 393 2.4E-151 T 11-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 UP12_06560 93b73aa2d3914a58aa9da80c9c9d3fdd 397 SUPERFAMILY SSF56112 7 393 2.19E-87 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_06560 93b73aa2d3914a58aa9da80c9c9d3fdd 397 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 397 188.654 T 11-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 UP12_06560 93b73aa2d3914a58aa9da80c9c9d3fdd 397 Pfam PF01636 Phosphotransferase enzyme family 34 268 2.0E-13 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase UP12_02290 bbfafbf2a2653f94c8507495361da056 360 Gene3D G3DSA:3.60.60.10 79 334 3.2E-40 T 11-10-2018 UP12_02290 bbfafbf2a2653f94c8507495361da056 360 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 105 324 5.5E-36 T 11-10-2018 IPR005079 Peptidase C45 UP12_02290 bbfafbf2a2653f94c8507495361da056 360 SUPERFAMILY SSF56235 103 261 7.56E-14 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_18660 adf58ea0e3d0f285fd526b0f34771592 226 Pfam PF11368 Protein of unknown function (DUF3169) 4 220 1.4E-21 T 11-10-2018 IPR021509 Protein of unknown function DUF3169 UP12_10210 1a30f4d496c840dcb3d43650f1ad0a86 320 SUPERFAMILY SSF48576 6 319 9.76E-86 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_10210 1a30f4d496c840dcb3d43650f1ad0a86 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 1.4E-168 T 11-10-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 UP12_10210 1a30f4d496c840dcb3d43650f1ad0a86 320 Pfam PF00348 Polyprenyl synthetase 31 254 4.9E-67 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 UP12_10210 1a30f4d496c840dcb3d43650f1ad0a86 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site UP12_10210 1a30f4d496c840dcb3d43650f1ad0a86 320 Gene3D G3DSA:1.10.600.10 7 320 5.0E-99 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_10210 1a30f4d496c840dcb3d43650f1ad0a86 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site UP12_16645 c4f5956241b9703955eda5b25a3d9ecc 309 Gene3D G3DSA:3.90.25.10 174 300 3.4E-96 T 11-10-2018 UP12_16645 c4f5956241b9703955eda5b25a3d9ecc 309 SUPERFAMILY SSF51735 1 306 4.64E-89 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16645 c4f5956241b9703955eda5b25a3d9ecc 309 Gene3D G3DSA:3.40.50.720 4 236 3.4E-96 T 11-10-2018 UP12_16645 c4f5956241b9703955eda5b25a3d9ecc 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 228 5.5E-58 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 UP12_04425 ba72792009c93a1fd15275c7ceed5f0f 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 427 5.4E-169 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UP12_04425 ba72792009c93a1fd15275c7ceed5f0f 431 Gene3D G3DSA:3.40.640.10 72 320 1.3E-168 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_04425 ba72792009c93a1fd15275c7ceed5f0f 431 SUPERFAMILY SSF53383 2 428 1.75E-123 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_04425 ba72792009c93a1fd15275c7ceed5f0f 431 Gene3D G3DSA:3.90.1150.10 9 423 1.3E-168 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_04425 ba72792009c93a1fd15275c7ceed5f0f 431 Pfam PF00202 Aminotransferase class-III 36 399 8.7E-71 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_04425 ba72792009c93a1fd15275c7ceed5f0f 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 UP12_04425 ba72792009c93a1fd15275c7ceed5f0f 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 92.454 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 UP12_05010 c34399704a21748e2585cb878036b219 424 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 2 335 3.2E-116 T 11-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase UP12_05010 c34399704a21748e2585cb878036b219 424 SUPERFAMILY SSF51905 2 226 2.59E-20 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05010 c34399704a21748e2585cb878036b219 424 Gene3D G3DSA:3.50.50.60 1 420 3.3E-114 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_00845 d8a191d5249abd95e0508039b5f500a5 72 Gene3D G3DSA:2.40.50.140 1 72 2.2E-38 T 11-10-2018 UP12_00845 d8a191d5249abd95e0508039b5f500a5 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.386 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 UP12_00845 d8a191d5249abd95e0508039b5f500a5 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.6E-39 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 UP12_00845 d8a191d5249abd95e0508039b5f500a5 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 6.7E-29 T 11-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 UP12_00845 d8a191d5249abd95e0508039b5f500a5 72 SUPERFAMILY SSF50249 1 71 5.14E-29 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_00845 d8a191d5249abd95e0508039b5f500a5 72 SMART SM00316 4 72 2.8E-6 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_18065 17967611074be8a609587b658517bf5f 373 Gene3D G3DSA:3.30.70.100 264 372 1.2E-32 T 11-10-2018 UP12_18065 17967611074be8a609587b658517bf5f 373 Pfam PF00005 ABC transporter 18 166 2.7E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18065 17967611074be8a609587b658517bf5f 373 Gene3D G3DSA:3.40.50.300 2 250 1.5E-59 T 11-10-2018 UP12_18065 17967611074be8a609587b658517bf5f 373 SUPERFAMILY SSF52540 4 229 8.88E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18065 17967611074be8a609587b658517bf5f 373 SUPERFAMILY SSF54909 267 363 1.49E-22 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_18065 17967611074be8a609587b658517bf5f 373 Pfam PF03992 Antibiotic biosynthesis monooxygenase 267 343 4.3E-15 T 11-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain UP12_18065 17967611074be8a609587b658517bf5f 373 SMART SM00382 27 224 1.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_14400 aef6771a17d6cbd97339fbd693e1c4b8 163 SUPERFAMILY SSF53098 1 141 2.73E-13 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_14400 aef6771a17d6cbd97339fbd693e1c4b8 163 Gene3D G3DSA:3.30.420.10 1 149 1.0E-23 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_11220 5dff6949441e889ccb0a4418acc0664d 212 SUPERFAMILY SSF56281 5 208 5.37E-50 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_11220 5dff6949441e889ccb0a4418acc0664d 212 Pfam PF00753 Metallo-beta-lactamase superfamily 11 191 7.8E-33 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_11220 5dff6949441e889ccb0a4418acc0664d 212 Gene3D G3DSA:3.60.15.10 1 211 2.6E-61 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_11220 5dff6949441e889ccb0a4418acc0664d 212 SMART SM00849 12 191 1.3E-39 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_07955 071695aa39346504c4b76244f1b8d859 374 SUPERFAMILY SSF103039 30 219 7.41E-50 T 11-10-2018 IPR028976 CheC-like superfamily UP12_07955 071695aa39346504c4b76244f1b8d859 374 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 291 366 6.1E-31 T 11-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 UP12_07955 071695aa39346504c4b76244f1b8d859 374 Gene3D G3DSA:3.40.1550.10 29 225 3.3E-54 T 11-10-2018 IPR028976 CheC-like superfamily UP12_07955 071695aa39346504c4b76244f1b8d859 374 Gene3D G3DSA:2.30.330.10 280 374 5.0E-35 T 11-10-2018 IPR036429 SpoA-like superfamily UP12_07955 071695aa39346504c4b76244f1b8d859 374 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 294 364 1.9E-24 T 11-10-2018 IPR001543 Surface presentation of antigen (SpoA) UP12_07955 071695aa39346504c4b76244f1b8d859 374 Pfam PF04509 CheC-like family 34 70 6.2E-15 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 UP12_07955 071695aa39346504c4b76244f1b8d859 374 Pfam PF04509 CheC-like family 131 167 7.5E-17 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 UP12_07955 071695aa39346504c4b76244f1b8d859 374 PRINTS PR00956 Flagellar motor switch protein FliN signature 311 327 2.2E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 UP12_07955 071695aa39346504c4b76244f1b8d859 374 PRINTS PR00956 Flagellar motor switch protein FliN signature 327 340 2.2E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 UP12_07955 071695aa39346504c4b76244f1b8d859 374 PRINTS PR00956 Flagellar motor switch protein FliN signature 294 310 2.2E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 UP12_07955 071695aa39346504c4b76244f1b8d859 374 PRINTS PR00956 Flagellar motor switch protein FliN signature 340 355 2.2E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 UP12_07955 071695aa39346504c4b76244f1b8d859 374 SUPERFAMILY SSF101801 292 372 1.83E-24 T 11-10-2018 IPR036429 SpoA-like superfamily UP12_00785 470536e00dec98a03299cdde4f4760d7 179 Gene3D G3DSA:3.30.1440.10 1 179 6.3E-84 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00785 470536e00dec98a03299cdde4f4760d7 179 Pfam PF00281 Ribosomal protein L5 24 80 4.6E-28 T 11-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00785 470536e00dec98a03299cdde4f4760d7 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 11-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00785 470536e00dec98a03299cdde4f4760d7 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 8.9E-43 T 11-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00785 470536e00dec98a03299cdde4f4760d7 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 45.713 T 11-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00785 470536e00dec98a03299cdde4f4760d7 179 SUPERFAMILY SSF55282 3 178 4.47E-79 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00785 470536e00dec98a03299cdde4f4760d7 179 PIRSF PIRSF002161 1 179 7.9E-70 T 11-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_09520 339064f5d00a3ded28b89bf2049a961a 316 Gene3D G3DSA:1.20.1530.20 1 307 3.3E-114 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily UP12_09520 339064f5d00a3ded28b89bf2049a961a 316 Pfam PF01758 Sodium Bile acid symporter family 42 220 7.0E-49 T 11-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UP12_04590 5180e749012f60f90a7d5b3ed2eb4e25 646 PIRSF PIRSF005091 1 620 3.4E-191 T 11-10-2018 IPR012160 Lipoteichoic acid synthase-like UP12_04590 5180e749012f60f90a7d5b3ed2eb4e25 646 Gene3D G3DSA:3.40.720.10 237 547 2.6E-79 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_04590 5180e749012f60f90a7d5b3ed2eb4e25 646 SUPERFAMILY SSF53649 243 635 1.8E-79 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_04590 5180e749012f60f90a7d5b3ed2eb4e25 646 Pfam PF00884 Sulfatase 245 537 1.3E-34 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 UP12_17620 a2872b735e11aa9302ef5270a960b1c8 473 Pfam PF13535 ATP-grasp domain 172 333 4.2E-13 T 11-10-2018 UP12_17620 a2872b735e11aa9302ef5270a960b1c8 473 Gene3D G3DSA:3.90.1170.60 373 467 1.2E-30 T 11-10-2018 UP12_17620 a2872b735e11aa9302ef5270a960b1c8 473 Gene3D G3DSA:3.30.470.20 229 372 2.9E-51 T 11-10-2018 UP12_17620 a2872b735e11aa9302ef5270a960b1c8 473 SUPERFAMILY SSF56059 128 373 1.08E-30 T 11-10-2018 UP12_17620 a2872b735e11aa9302ef5270a960b1c8 473 Gene3D G3DSA:3.30.1490.20 137 228 5.0E-18 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UP12_17620 a2872b735e11aa9302ef5270a960b1c8 473 Gene3D G3DSA:3.40.50.20 1 136 2.9E-64 T 11-10-2018 UP12_05300 21a63a4d9b697caa4b511a04674eb72d 279 Pfam PF05569 BlaR1 peptidase M56 119 244 4.0E-12 T 11-10-2018 IPR008756 Peptidase M56 UP12_05300 21a63a4d9b697caa4b511a04674eb72d 279 Gene3D G3DSA:3.30.2010.10 82 166 1.1E-6 T 11-10-2018 UP12_10990 071b0547eeb8021c5a42e82882a4780f 131 Gene3D G3DSA:1.10.940.10 1 131 1.7E-45 T 11-10-2018 IPR035926 NusB-like superfamily UP12_10990 071b0547eeb8021c5a42e82882a4780f 131 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 127 3.3E-44 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 UP12_10990 071b0547eeb8021c5a42e82882a4780f 131 Pfam PF01029 NusB family 4 125 2.6E-40 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 UP12_10990 071b0547eeb8021c5a42e82882a4780f 131 SUPERFAMILY SSF48013 2 127 8.37E-41 T 11-10-2018 IPR035926 NusB-like superfamily UP12_10990 071b0547eeb8021c5a42e82882a4780f 131 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 129 24.924 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 UP12_02030 6e5ad0420eb84b7c7b1203cfc08b548c 304 Pfam PF00892 EamA-like transporter family 8 142 1.5E-26 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_02030 6e5ad0420eb84b7c7b1203cfc08b548c 304 Pfam PF00892 EamA-like transporter family 154 294 1.3E-22 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_02030 6e5ad0420eb84b7c7b1203cfc08b548c 304 SUPERFAMILY SSF103481 215 296 1.12E-11 T 11-10-2018 UP12_02030 6e5ad0420eb84b7c7b1203cfc08b548c 304 SUPERFAMILY SSF103481 47 143 4.84E-14 T 11-10-2018 UP12_15090 ae1d05b6a2249a1f06a76b944f61e7b4 258 Pfam PF07070 SpoOM protein 4 212 1.3E-71 T 11-10-2018 IPR009776 Sporulation stage 0, protein M UP12_15090 ae1d05b6a2249a1f06a76b944f61e7b4 258 Gene3D G3DSA:2.60.40.640 15 132 4.1E-7 T 11-10-2018 IPR014752 Arrestin, C-terminal UP12_15090 ae1d05b6a2249a1f06a76b944f61e7b4 258 SUPERFAMILY SSF81296 17 110 1.12E-8 T 11-10-2018 IPR014756 Immunoglobulin E-set UP12_16415 8029cce267b208e3fe44eafe0e7dcc09 228 Pfam PF00072 Response regulator receiver domain 7 116 2.0E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16415 8029cce267b208e3fe44eafe0e7dcc09 228 Gene3D G3DSA:1.10.10.10 130 228 5.1E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16415 8029cce267b208e3fe44eafe0e7dcc09 228 SUPERFAMILY SSF52172 4 184 6.83E-49 T 11-10-2018 IPR011006 CheY-like superfamily UP12_16415 8029cce267b208e3fe44eafe0e7dcc09 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 4.0E-24 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_16415 8029cce267b208e3fe44eafe0e7dcc09 228 SMART SM00448 5 115 1.8E-50 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16415 8029cce267b208e3fe44eafe0e7dcc09 228 SMART SM00862 150 224 3.2E-26 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_16415 8029cce267b208e3fe44eafe0e7dcc09 228 Gene3D G3DSA:3.40.50.2300 1 129 6.4E-44 T 11-10-2018 UP12_02865 bd1429232edb92a757f654518efd5d0a 133 Gene3D G3DSA:1.10.1660.10 1 132 4.4E-32 T 11-10-2018 UP12_02865 bd1429232edb92a757f654518efd5d0a 133 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_02865 bd1429232edb92a757f654518efd5d0a 133 SUPERFAMILY SSF46955 1 118 2.01E-29 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_02865 bd1429232edb92a757f654518efd5d0a 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.8E-5 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_02865 bd1429232edb92a757f654518efd5d0a 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.8E-5 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_02865 bd1429232edb92a757f654518efd5d0a 133 SMART SM00422 1 70 1.3E-22 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_02865 bd1429232edb92a757f654518efd5d0a 133 Pfam PF13411 MerR HTH family regulatory protein 1 66 1.3E-18 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_03135 5fdadb609df411d4e4965eac0317202b 142 Gene3D G3DSA:3.40.630.30 1 142 9.8E-45 T 11-10-2018 UP12_03135 5fdadb609df411d4e4965eac0317202b 142 Pfam PF00583 Acetyltransferase (GNAT) family 7 116 9.8E-24 T 11-10-2018 IPR000182 GNAT domain UP12_03135 5fdadb609df411d4e4965eac0317202b 142 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 6 136 3.3E-43 T 11-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 UP12_03135 5fdadb609df411d4e4965eac0317202b 142 SUPERFAMILY SSF55729 1 140 1.02E-35 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_05675 d7e154604b6bde7483757a81e1783399 304 Gene3D G3DSA:1.10.3720.10 91 299 9.1E-19 T 11-10-2018 IPR035906 MetI-like superfamily UP12_05675 d7e154604b6bde7483757a81e1783399 304 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 77 7.0E-15 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UP12_05675 d7e154604b6bde7483757a81e1783399 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 302 5.0E-29 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_05675 d7e154604b6bde7483757a81e1783399 304 SUPERFAMILY SSF161098 95 288 5.1E-25 T 11-10-2018 IPR035906 MetI-like superfamily UP12_02220 06aabfe903ecbdf39bff4b0617a87f5b 130 Pfam PF01042 Endoribonuclease L-PSP 11 125 2.5E-17 T 11-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UP12_02220 06aabfe903ecbdf39bff4b0617a87f5b 130 Gene3D G3DSA:3.30.1330.40 2 129 1.9E-23 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_02220 06aabfe903ecbdf39bff4b0617a87f5b 130 SUPERFAMILY SSF55298 3 128 3.14E-27 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 Gene3D G3DSA:3.40.50.720 2 267 1.1E-53 T 11-10-2018 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 202 449 6.4E-51 T 11-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 SUPERFAMILY SSF51735 4 266 9.84E-69 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_15600 9f9d97514f28889b4295aac043f03e10 485 Gene3D G3DSA:1.10.1040.10 270 475 3.3E-53 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 SUPERFAMILY SSF48179 271 475 5.44E-41 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 PRINTS PR00084 Mannitol dehydrogenase signature 18 28 1.2E-5 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 PRINTS PR00084 Mannitol dehydrogenase signature 233 248 1.2E-5 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 PRINTS PR00084 Mannitol dehydrogenase signature 162 175 1.2E-5 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 PRINTS PR00084 Mannitol dehydrogenase signature 203 216 1.2E-5 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_15600 9f9d97514f28889b4295aac043f03e10 485 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 17 170 1.2E-21 T 11-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_14245 f3012db4ec193c76f7ad58a8741022a3 130 Gene3D G3DSA:1.10.3230.10 1 130 9.6E-51 T 11-10-2018 IPR036558 YqbG-like superfamily UP12_14245 f3012db4ec193c76f7ad58a8741022a3 130 Pfam PF11436 Protein of unknown function (DUF3199) 2 128 1.6E-56 T 11-10-2018 IPR013514 Protein of unknown function DUF3199, YqbG UP12_14245 f3012db4ec193c76f7ad58a8741022a3 130 SUPERFAMILY SSF116915 1 129 1.22E-52 T 11-10-2018 IPR036558 YqbG-like superfamily UP12_15330 2b499e502ec78965881c737bc0b394d5 231 Gene3D G3DSA:3.40.50.2300 2 129 7.5E-36 T 11-10-2018 UP12_15330 2b499e502ec78965881c737bc0b394d5 231 SUPERFAMILY SSF52172 2 129 1.07E-38 T 11-10-2018 IPR011006 CheY-like superfamily UP12_15330 2b499e502ec78965881c737bc0b394d5 231 Pfam PF00072 Response regulator receiver domain 5 112 2.5E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_15330 2b499e502ec78965881c737bc0b394d5 231 Gene3D G3DSA:1.10.10.10 130 231 4.0E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15330 2b499e502ec78965881c737bc0b394d5 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 2.8E-23 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_15330 2b499e502ec78965881c737bc0b394d5 231 SUPERFAMILY SSF46894 127 228 3.97E-24 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_15330 2b499e502ec78965881c737bc0b394d5 231 SMART SM00862 151 228 2.7E-24 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_15330 2b499e502ec78965881c737bc0b394d5 231 SMART SM00448 3 112 1.1E-43 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 2.0E-34 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 4.1E-11 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 4.1E-11 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 4.1E-11 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 11-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 Pfam PF00366 Ribosomal protein S17 12 79 1.4E-31 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 1.2E-34 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 SUPERFAMILY SSF50249 7 84 1.03E-30 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 23.792 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00770 9b9631dac328c7f4cb721b1cbdabd8e6 87 Gene3D G3DSA:2.40.50.140 6 86 3.2E-34 T 11-10-2018 UP12_12090 28206e9d0a9f5fa2dd2ec1e1717690dd 774 Gene3D G3DSA:3.90.1640.30 57 318 4.7E-98 T 11-10-2018 UP12_12090 28206e9d0a9f5fa2dd2ec1e1717690dd 774 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 566 763 7.1E-66 T 11-10-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal UP12_12090 28206e9d0a9f5fa2dd2ec1e1717690dd 774 SUPERFAMILY SSF64182 57 450 2.49E-122 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily UP12_12090 28206e9d0a9f5fa2dd2ec1e1717690dd 774 Gene3D G3DSA:3.10.310.30 319 442 2.1E-34 T 11-10-2018 UP12_12090 28206e9d0a9f5fa2dd2ec1e1717690dd 774 Pfam PF01368 DHH family 83 225 5.0E-10 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_12090 28206e9d0a9f5fa2dd2ec1e1717690dd 774 Pfam PF02272 DHHA1 domain 314 437 9.0E-19 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 UP12_12090 28206e9d0a9f5fa2dd2ec1e1717690dd 774 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 559 2.9E-187 T 11-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 UP12_04880 e006d5c27b37d424f0943732309980e0 200 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 19 141 2.6E-34 T 11-10-2018 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|MetaCyc: PWY-7782|Reactome: R-HSA-1483166 UP12_04880 e006d5c27b37d424f0943732309980e0 200 SMART SM00563 33 144 8.4E-28 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UP12_04880 e006d5c27b37d424f0943732309980e0 200 Pfam PF01553 Acyltransferase 19 142 7.1E-22 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UP12_04880 e006d5c27b37d424f0943732309980e0 200 SUPERFAMILY SSF69593 2 192 5.89E-35 T 11-10-2018 UP12_10930 4d08366fafa1c335ceb4c97687bc598e 366 Gene3D G3DSA:1.25.40.10 3 365 6.7E-84 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10930 4d08366fafa1c335ceb4c97687bc598e 366 SUPERFAMILY SSF48452 107 288 4.68E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_17380 651d6f1e0410900918fce693a50387e0 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_17380 651d6f1e0410900918fce693a50387e0 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 6.9E-54 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 UP12_17380 651d6f1e0410900918fce693a50387e0 380 SUPERFAMILY SSF47203 227 379 2.42E-62 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 UP12_17380 651d6f1e0410900918fce693a50387e0 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 UP12_17380 651d6f1e0410900918fce693a50387e0 380 Gene3D G3DSA:1.20.140.10 235 380 3.2E-59 T 11-10-2018 UP12_17380 651d6f1e0410900918fce693a50387e0 380 Gene3D G3DSA:2.40.110.10 121 234 3.7E-43 T 11-10-2018 UP12_17380 651d6f1e0410900918fce693a50387e0 380 PIRSF PIRSF016578 3 216 2.0E-8 T 11-10-2018 UP12_17380 651d6f1e0410900918fce693a50387e0 380 PIRSF PIRSF016578 220 379 3.3E-11 T 11-10-2018 UP12_17380 651d6f1e0410900918fce693a50387e0 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 2.7E-26 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 UP12_17380 651d6f1e0410900918fce693a50387e0 380 SUPERFAMILY SSF56645 2 242 3.8E-87 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 UP12_17380 651d6f1e0410900918fce693a50387e0 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 2.1E-39 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 UP12_17380 651d6f1e0410900918fce693a50387e0 380 Gene3D G3DSA:1.10.540.10 1 120 3.1E-44 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 UP12_01135 32f454604125a5f92e798bad4a80219a 254 Pfam PF12679 ABC-2 family transporter protein 2 214 1.4E-10 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UP12_17080 0895be9e355d2c8938c75ce4d85a70d1 185 Pfam PF07291 Methylamine utilisation protein MauE 11 161 5.9E-14 T 11-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 UP12_10865 0ef2cd7e2cb19010841d5cd8638913e1 145 Gene3D G3DSA:3.40.30.10 25 142 7.2E-53 T 11-10-2018 UP12_10865 0ef2cd7e2cb19010841d5cd8638913e1 145 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 142 2.6E-62 T 11-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family UP12_10865 0ef2cd7e2cb19010841d5cd8638913e1 145 Pfam PF06491 Disulphide isomerase 8 142 3.0E-61 T 11-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 353 1.3E-17 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 11-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 SUPERFAMILY SSF52540 1 353 1.06E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 366 1.5E-138 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 Gene3D G3DSA:3.40.50.300 6 345 2.6E-109 T 11-10-2018 UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 370 104.333 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 Gene3D G3DSA:1.20.1050.90 119 311 2.6E-109 T 11-10-2018 UP12_00020 b84e5ddfb05a09c3a3bcff7b95e2c9e4 370 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 11-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 UP12_10780 804676cd8f7e210f1fb6f1ad9b29da45 103 SUPERFAMILY SSF52794 1 102 9.68E-33 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_10780 804676cd8f7e210f1fb6f1ad9b29da45 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 95 4.3E-18 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_10780 804676cd8f7e210f1fb6f1ad9b29da45 103 Gene3D G3DSA:3.40.50.2300 2 103 1.7E-31 T 11-10-2018 UP12_09130 04f5e688b9e941f66d19fa7ad99b6aeb 260 Gene3D G3DSA:3.90.226.10 2 201 5.9E-72 T 11-10-2018 UP12_09130 04f5e688b9e941f66d19fa7ad99b6aeb 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 259 1.9E-65 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UP12_09130 04f5e688b9e941f66d19fa7ad99b6aeb 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 UP12_09130 04f5e688b9e941f66d19fa7ad99b6aeb 260 Gene3D G3DSA:1.10.12.10 202 260 7.6E-21 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal UP12_09130 04f5e688b9e941f66d19fa7ad99b6aeb 260 SUPERFAMILY SSF52096 9 259 1.35E-83 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_17595 2023310baea4a33c70cd040f5059c44a 159 Gene3D G3DSA:1.10.10.10 1 54 2.6E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_17595 2023310baea4a33c70cd040f5059c44a 159 Gene3D G3DSA:3.30.70.920 55 140 5.8E-18 T 11-10-2018 UP12_17595 2023310baea4a33c70cd040f5059c44a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 4.5E-15 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_17595 2023310baea4a33c70cd040f5059c44a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 4.5E-15 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_17595 2023310baea4a33c70cd040f5059c44a 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 4.5E-15 T 11-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 UP12_17595 2023310baea4a33c70cd040f5059c44a 159 SUPERFAMILY SSF46785 3 62 7.58E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_17595 2023310baea4a33c70cd040f5059c44a 159 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 11-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site UP12_17595 2023310baea4a33c70cd040f5059c44a 159 SMART SM00344 3 109 1.1E-32 T 11-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UP12_17595 2023310baea4a33c70cd040f5059c44a 159 SUPERFAMILY SSF54909 67 136 3.89E-12 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_17595 2023310baea4a33c70cd040f5059c44a 159 Pfam PF01037 Lrp/AsnC ligand binding domain 70 136 4.1E-10 T 11-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UP12_17595 2023310baea4a33c70cd040f5059c44a 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 50 6.5E-17 T 11-10-2018 UP12_18830 e68cb4fbc1c98275eae5ba2e2005cfc9 159 SUPERFAMILY SSF75217 2 157 7.85E-63 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases UP12_18830 e68cb4fbc1c98275eae5ba2e2005cfc9 159 Pfam PF02590 Predicted SPOUT methyltransferase 2 158 1.6E-60 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 UP12_18830 e68cb4fbc1c98275eae5ba2e2005cfc9 159 Gene3D G3DSA:3.40.1280.10 1 159 4.3E-70 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UP12_18830 e68cb4fbc1c98275eae5ba2e2005cfc9 159 PIRSF PIRSF004505 1 159 2.3E-54 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 UP12_18830 e68cb4fbc1c98275eae5ba2e2005cfc9 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 1 159 1.7E-75 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 UP12_18830 e68cb4fbc1c98275eae5ba2e2005cfc9 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.693 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 UP12_13290 45445ca4c0a3c7dbae05ce384bf25532 450 SUPERFAMILY SSF51556 57 367 4.22E-63 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_13290 45445ca4c0a3c7dbae05ce384bf25532 450 Gene3D G3DSA:3.20.20.140 59 426 4.1E-108 T 11-10-2018 UP12_13290 45445ca4c0a3c7dbae05ce384bf25532 450 Pfam PF01979 Amidohydrolase family 54 415 4.6E-29 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UP12_13290 45445ca4c0a3c7dbae05ce384bf25532 450 Gene3D G3DSA:2.30.40.10 11 421 4.1E-108 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_13290 45445ca4c0a3c7dbae05ce384bf25532 450 SUPERFAMILY SSF51338 3 440 1.31E-27 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_15050 fcae042b8bb26a7ecbbb4e7486e950ff 964 TIGRFAM TIGR03929 T7_esaA_Nterm: type VII secretion protein EsaA 11 200 6.3E-78 T 11-10-2018 IPR023838 Type VII secretion system EsaA GO:0016021 UP12_15050 fcae042b8bb26a7ecbbb4e7486e950ff 964 Pfam PF12698 ABC-2 family transporter protein 13 141 4.2E-8 T 11-10-2018 UP12_04445 a54b1522aae8f7c7a9f3df6183a0d8cf 292 Gene3D G3DSA:3.30.460.10 1 114 2.3E-42 T 11-10-2018 UP12_04445 a54b1522aae8f7c7a9f3df6183a0d8cf 292 ProDom PD128250 YGXA BH0953 1 279 1.0E-131 T 11-10-2018 UP12_04445 a54b1522aae8f7c7a9f3df6183a0d8cf 292 Gene3D G3DSA:1.20.120.330 115 232 4.7E-47 T 11-10-2018 UP12_04445 a54b1522aae8f7c7a9f3df6183a0d8cf 292 Pfam PF14540 Nucleotidyltransferase-like 1 118 7.5E-48 T 11-10-2018 IPR029348 Nucleotidyltransferase-like domain UP12_14200 8cc2db27d18b947d1ca0189fe3da690a 1658 SUPERFAMILY SSF53955 1440 1511 1.39E-10 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_14200 8cc2db27d18b947d1ca0189fe3da690a 1658 Gene3D G3DSA:1.10.530.10 1427 1531 6.6E-6 T 11-10-2018 UP12_14200 8cc2db27d18b947d1ca0189fe3da690a 1658 Pfam PF01464 Transglycosylase SLT domain 1428 1551 9.4E-18 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 UP12_04870 bb905767247b7981884aff14217910f4 352 Pfam PF13800 Sigma factor regulator N-terminal 56 150 1.9E-20 T 11-10-2018 IPR029101 Sigma factor regulator, N-terminal UP12_04870 bb905767247b7981884aff14217910f4 352 Pfam PF13791 Sigma factor regulator C-terminal 202 345 2.3E-36 T 11-10-2018 IPR025672 Sigma factor regulator C-terminal domain UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 Pfam PF13426 PAS domain 31 129 8.5E-16 T 11-10-2018 IPR000014 PAS domain UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 19 134 2.5E-20 T 11-10-2018 IPR000014 PAS domain UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 171 303 4.6E-27 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 Gene3D G3DSA:1.10.287.950 122 306 8.1E-34 T 11-10-2018 UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 SMART SM00283 104 306 3.4E-4 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 SMART SM00086 88 130 2.6E-5 T 11-10-2018 IPR001610 PAC motif UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 SUPERFAMILY SSF58104 104 303 1.57E-39 T 11-10-2018 UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 Gene3D G3DSA:3.30.450.20 2 121 1.1E-21 T 11-10-2018 UP12_12995 bbd7d6ca4d797d0cb9c6c24f8a3ad298 306 SUPERFAMILY SSF55785 25 127 3.32E-25 T 11-10-2018 IPR035965 PAS domain superfamily UP12_10700 3f6bb072fbbebd8cf1bf1830f4e865bd 319 SUPERFAMILY SSF52540 11 317 5.74E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10700 3f6bb072fbbebd8cf1bf1830f4e865bd 319 Hamap MF_00215 Pantothenate kinase [coaA]. 1 319 151.129 T 11-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UP12_10700 3f6bb072fbbebd8cf1bf1830f4e865bd 319 PIRSF PIRSF000545 2 319 4.2E-135 T 11-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UP12_10700 3f6bb072fbbebd8cf1bf1830f4e865bd 319 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 91 234 5.1E-13 T 11-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 UP12_10700 3f6bb072fbbebd8cf1bf1830f4e865bd 319 Gene3D G3DSA:3.40.50.300 3 319 8.1E-94 T 11-10-2018 UP12_10700 3f6bb072fbbebd8cf1bf1830f4e865bd 319 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 12 318 6.0E-145 T 11-10-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 13 173 3.2E-45 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 Gene3D G3DSA:3.40.50.1440 6 220 1.1E-84 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 SMART SM00865 207 324 1.5E-53 T 11-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 SUPERFAMILY SSF55307 204 315 6.41E-43 T 11-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 Pfam PF12327 FtsZ family, C-terminal domain 222 315 7.6E-32 T 11-10-2018 IPR024757 Cell division protein FtsZ, C-terminal UP12_07415 ae930de224f2ee7d330af761e89412e3 381 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 334 2.4E-140 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 SMART SM00864 13 205 5.9E-119 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 SUPERFAMILY SSF52490 13 208 1.57E-73 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 370 39.51 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.3E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.3E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.3E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.3E-52 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 UP12_07415 ae930de224f2ee7d330af761e89412e3 381 Gene3D G3DSA:3.30.1330.20 221 330 1.3E-41 T 11-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 UP12_18075 e7788fc85a3bb29f0ec1eb2d9e0a8fec 312 Pfam PF01497 Periplasmic binding protein 54 286 4.6E-38 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_18075 e7788fc85a3bb29f0ec1eb2d9e0a8fec 312 Gene3D G3DSA:3.40.50.1980 31 131 2.2E-16 T 11-10-2018 UP12_18075 e7788fc85a3bb29f0ec1eb2d9e0a8fec 312 Gene3D G3DSA:3.40.50.1980 138 308 3.7E-47 T 11-10-2018 UP12_18075 e7788fc85a3bb29f0ec1eb2d9e0a8fec 312 SUPERFAMILY SSF53807 36 293 1.22E-55 T 11-10-2018 UP12_00480 459a08643113489f85f43ebade68d583 333 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 320 1.0E-140 T 11-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 UP12_00480 459a08643113489f85f43ebade68d583 333 Gene3D G3DSA:1.10.1200.80 254 330 1.7E-19 T 11-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 UP12_00480 459a08643113489f85f43ebade68d583 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 11-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 UP12_00480 459a08643113489f85f43ebade68d583 333 Gene3D G3DSA:3.20.20.70 7 251 2.0E-81 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_00480 459a08643113489f85f43ebade68d583 333 Pfam PF01207 Dihydrouridine synthase (Dus) 14 318 1.5E-113 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UP12_00480 459a08643113489f85f43ebade68d583 333 SUPERFAMILY SSF51395 11 318 1.14E-90 T 11-10-2018 UP12_00480 459a08643113489f85f43ebade68d583 333 PIRSF PIRSF006621 1 330 3.0E-107 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 UP12_14885 2cad8e975edff097d3f154a455684869 235 SUPERFAMILY SSF46785 176 230 1.8E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_14885 2cad8e975edff097d3f154a455684869 235 PIRSF PIRSF006171 1 227 2.6E-82 T 11-10-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0000160|GO:0003700 UP12_14885 2cad8e975edff097d3f154a455684869 235 SUPERFAMILY SSF52172 1 148 2.99E-36 T 11-10-2018 IPR011006 CheY-like superfamily UP12_14885 2cad8e975edff097d3f154a455684869 235 Gene3D G3DSA:3.40.50.2300 1 137 7.5E-32 T 11-10-2018 UP12_14885 2cad8e975edff097d3f154a455684869 235 Pfam PF00072 Response regulator receiver domain 4 115 6.8E-27 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_14885 2cad8e975edff097d3f154a455684869 235 SMART SM00448 2 115 2.1E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_16320 8b3593d06c012400ee840c8bc6db6f27 274 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UP12_16320 8b3593d06c012400ee840c8bc6db6f27 274 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 10 255 2.9E-80 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UP12_16320 8b3593d06c012400ee840c8bc6db6f27 274 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 1 261 1.1E-88 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UP12_16320 8b3593d06c012400ee840c8bc6db6f27 274 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 261 18.038 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 UP12_02235 5289fa5cf1579f4b2a8d7113de774ae5 125 Gene3D G3DSA:3.10.180.10 1 125 1.7E-31 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_02235 5289fa5cf1579f4b2a8d7113de774ae5 125 Pfam PF12681 Glyoxalase-like domain 3 124 1.7E-30 T 11-10-2018 IPR025870 Glyoxalase-like domain UP12_02235 5289fa5cf1579f4b2a8d7113de774ae5 125 SUPERFAMILY SSF54593 1 121 1.32E-30 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_18540 a8f4f16b78fd877367a19d3e79311874 442 TIGRFAM TIGR00784 citMHS: citrate transporter 1 442 5.9E-102 T 11-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 UP12_18540 a8f4f16b78fd877367a19d3e79311874 442 Pfam PF03600 Citrate transporter 14 389 2.4E-43 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 319 7.1E-27 T 11-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 SUPERFAMILY SSF53822 61 323 1.26E-49 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 SMART SM00354 1 71 3.6E-29 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 11-10-2018 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 Gene3D G3DSA:3.40.50.2300 158 285 5.0E-54 T 11-10-2018 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 Gene3D G3DSA:3.40.50.2300 63 303 5.0E-54 T 11-10-2018 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 SUPERFAMILY SSF47413 2 59 1.69E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.7E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.7E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.4E-19 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 UP12_06690 6b0ce3d907cff09682bfcafb1a75d977 325 Gene3D G3DSA:1.10.260.40 2 59 6.5E-20 T 11-10-2018 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 Gene3D G3DSA:3.40.228.10 199 420 1.3E-105 T 11-10-2018 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 SUPERFAMILY SSF50692 641 759 2.49E-13 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 Pfam PF01568 Molydopterin dinucleotide binding domain 656 752 7.9E-11 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 Gene3D G3DSA:2.40.40.20 640 760 6.6E-8 T 11-10-2018 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 19 758 1.7E-265 T 11-10-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 SUPERFAMILY SSF53706 71 643 1.57E-126 T 11-10-2018 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 Pfam PF00384 Molybdopterin oxidoreductase 123 576 2.1E-43 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 PIRSF PIRSF000144 83 761 2.8E-112 T 11-10-2018 UP12_17135 bda4aeaab630f9d8332be89979768a8d 782 Gene3D G3DSA:3.40.50.740 128 619 1.3E-105 T 11-10-2018 UP12_10455 b4dc59d3a8ce8a8d5a0d4d228fe912ee 174 SUPERFAMILY SSF140663 2 127 4.58E-31 T 11-10-2018 IPR023203 TTHA0068-like superfamily UP12_10455 b4dc59d3a8ce8a8d5a0d4d228fe912ee 174 Pfam PF03745 Domain of unknown function (DUF309) 7 66 1.1E-23 T 11-10-2018 IPR005500 Protein of unknown function DUF309 UP12_10455 b4dc59d3a8ce8a8d5a0d4d228fe912ee 174 Gene3D G3DSA:1.20.58.500 4 101 5.0E-15 T 11-10-2018 UP12_12695 e4147f38d50c03678791155f068f0dae 180 Pfam PF00589 Phage integrase family 14 164 3.0E-23 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UP12_12695 e4147f38d50c03678791155f068f0dae 180 SUPERFAMILY SSF56349 6 178 1.74E-38 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UP12_12695 e4147f38d50c03678791155f068f0dae 180 Gene3D G3DSA:1.10.443.10 9 179 3.9E-32 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UP12_07890 0d6c436bab3c634235cb387369e00114 105 Pfam PF02049 Flagellar hook-basal body complex protein FliE 20 105 3.5E-28 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 UP12_07890 0d6c436bab3c634235cb387369e00114 105 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 105 18.099 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 UP12_07890 0d6c436bab3c634235cb387369e00114 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 69 85 1.5E-16 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 UP12_07890 0d6c436bab3c634235cb387369e00114 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 90 103 1.5E-16 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 UP12_07890 0d6c436bab3c634235cb387369e00114 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 35 51 1.5E-16 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 UP12_07890 0d6c436bab3c634235cb387369e00114 105 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 4 105 1.5E-31 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 Gene3D G3DSA:2.30.24.10 1 55 1.0E-23 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 Pfam PF00874 PRD domain 75 162 2.0E-25 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 Pfam PF00874 PRD domain 181 272 3.4E-20 T 11-10-2018 IPR011608 PRD domain GO:0006355 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 SMART SM01061 1 59 1.1E-29 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 Gene3D G3DSA:1.10.1790.10 168 277 1.6E-37 T 11-10-2018 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 Gene3D G3DSA:1.10.1790.10 64 167 4.6E-37 T 11-10-2018 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 Pfam PF03123 CAT RNA binding domain 2 54 3.4E-23 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 SUPERFAMILY SSF63520 58 167 1.03E-31 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 SUPERFAMILY SSF50151 2 53 2.62E-17 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 UP12_01375 5baf26728579becf3a1d14bdb1ad4bfa 278 SUPERFAMILY SSF63520 170 274 1.29E-27 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 SUPERFAMILY SSF143800 1 65 5.89E-26 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 Gene3D G3DSA:2.30.170.50 1 66 7.7E-33 T 11-10-2018 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 7.3E-32 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 1.4E-22 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.4E-22 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 1.4E-22 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 28.765 T 11-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_17300 502a7ded979a1d8ab670adde0a2d3c89 66 Pfam PF01197 Ribosomal protein L31 1 64 5.3E-32 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 PIRSF PIRSF001415 1 323 1.1E-156 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 Gene3D G3DSA:3.20.20.70 1 322 6.6E-153 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 240 256 4.4E-59 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 120 134 4.4E-59 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 150 169 4.4E-59 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 295 314 4.4E-59 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 265 280 4.4E-59 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 188 207 4.4E-59 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 240 252 - T 11-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 SUPERFAMILY SSF51569 3 322 6.01E-146 T 11-10-2018 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 SMART SM01004 2 321 1.7E-243 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_12340 c9728b89b7d57719a97521447af5cbf5 323 Pfam PF00490 Delta-aminolevulinic acid dehydratase 5 320 3.4E-152 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 SMART SM00422 4 73 6.6E-22 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 5.6E-8 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 5.6E-8 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 5.6E-8 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 SUPERFAMILY SSF46955 4 115 2.42E-29 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 Gene3D G3DSA:1.10.1660.10 1 121 3.7E-30 T 11-10-2018 UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 Pfam PF13411 MerR HTH family regulatory protein 4 71 1.4E-18 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_08960 1ba7382fe4db0f011ff5e76b2fbeead2 136 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_05705 ead4a623d0a213e3a36b684a14b3a709 359 SUPERFAMILY SSF52540 6 256 5.33E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05705 ead4a623d0a213e3a36b684a14b3a709 359 Pfam PF00005 ABC transporter 27 185 3.6E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_05705 ead4a623d0a213e3a36b684a14b3a709 359 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_05705 ead4a623d0a213e3a36b684a14b3a709 359 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 323 3.4E-18 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_05705 ead4a623d0a213e3a36b684a14b3a709 359 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 302 1.7E-12 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_05705 ead4a623d0a213e3a36b684a14b3a709 359 Gene3D G3DSA:3.40.50.300 4 333 4.7E-98 T 11-10-2018 UP12_05705 ead4a623d0a213e3a36b684a14b3a709 359 SMART SM00382 35 243 1.1E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_14145 854ab65e3a02e701efed45212de3b81e 70 Pfam PF10960 BhlA holin family 2 64 3.3E-21 T 11-10-2018 IPR024405 Prophage protein BhlA/UviB UP12_14145 854ab65e3a02e701efed45212de3b81e 70 ProDom PD019268 UVIB BACTERIOCIN BHLA PLASMID ANTIBIOTIC HOLIN-LIKE PRECURSOR ANTIMICROBIAL SIGNAL PROPHAGE-DERIVED 1 64 8.0E-24 T 11-10-2018 IPR024405 Prophage protein BhlA/UviB UP12_13795 4b758e0c3f24558daf27af4bbf9a73db 158 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UP12_13795 4b758e0c3f24558daf27af4bbf9a73db 158 Gene3D G3DSA:3.90.79.10 1 158 2.8E-47 T 11-10-2018 UP12_13795 4b758e0c3f24558daf27af4bbf9a73db 158 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 156 4.5E-67 T 11-10-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 UP12_13795 4b758e0c3f24558daf27af4bbf9a73db 158 PRINTS PR00502 NUDIX hydrolase family signature 62 77 2.0E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_13795 4b758e0c3f24558daf27af4bbf9a73db 158 PRINTS PR00502 NUDIX hydrolase family signature 48 62 2.0E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_13795 4b758e0c3f24558daf27af4bbf9a73db 158 Pfam PF00293 NUDIX domain 31 87 1.2E-12 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UP12_13795 4b758e0c3f24558daf27af4bbf9a73db 158 SUPERFAMILY SSF55811 24 110 3.93E-20 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 8 432 4.8E-226 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 Pfam PF02040 Arsenical pump membrane protein 8 430 5.4E-247 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 283 307 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 328 350 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 369 394 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 402 426 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 106 130 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 149 173 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 182 205 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_08830 2d9cf4ea20278a4871d995e9f5fcb58a 434 PRINTS PR00758 Arsenical pump membrane protein signature 222 247 1.3E-112 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_12075 a7527fa27fead767acd4bf9ffc78b7e8 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 7.0E-67 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 UP12_12075 a7527fa27fead767acd4bf9ffc78b7e8 147 Gene3D G3DSA:3.50.80.10 1 147 2.9E-62 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily UP12_12075 a7527fa27fead767acd4bf9ffc78b7e8 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 2.5E-60 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 UP12_12075 a7527fa27fead767acd4bf9ffc78b7e8 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 35.466 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 UP12_12075 a7527fa27fead767acd4bf9ffc78b7e8 147 SUPERFAMILY SSF69500 1 145 7.59E-60 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily UP12_13770 417065f2e6af5be860880778c5c083ab 248 SUPERFAMILY SSF69593 24 193 4.18E-13 T 11-10-2018 UP12_13770 417065f2e6af5be860880778c5c083ab 248 SMART SM00563 44 161 2.1E-12 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UP12_13770 417065f2e6af5be860880778c5c083ab 248 Pfam PF01553 Acyltransferase 41 157 4.0E-13 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 UP12_15195 7106d44e5a10d29c914fec27dca1442e 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 289 3.2E-66 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 UP12_15195 7106d44e5a10d29c914fec27dca1442e 324 SUPERFAMILY SSF52283 3 139 1.63E-35 T 11-10-2018 UP12_15195 7106d44e5a10d29c914fec27dca1442e 324 SUPERFAMILY SSF51735 103 290 2.6E-63 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_15195 7106d44e5a10d29c914fec27dca1442e 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 320 6.2E-32 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 UP12_15195 7106d44e5a10d29c914fec27dca1442e 324 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 UP12_15195 7106d44e5a10d29c914fec27dca1442e 324 Gene3D G3DSA:3.40.50.720 6 315 1.7E-122 T 11-10-2018 UP12_15195 7106d44e5a10d29c914fec27dca1442e 324 Gene3D G3DSA:3.40.50.720 100 289 1.7E-122 T 11-10-2018 UP12_09595 9b142a3a3b95f4aa20db4810f94b4d93 110 SUPERFAMILY SSF46785 5 106 1.59E-27 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09595 9b142a3a3b95f4aa20db4810f94b4d93 110 Gene3D G3DSA:1.10.10.10 3 109 6.9E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09595 9b142a3a3b95f4aa20db4810f94b4d93 110 Pfam PF01638 HxlR-like helix-turn-helix 15 104 9.4E-34 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_12330 3675104e0c3ed85e4e8deac38f781268 418 Gene3D G3DSA:3.10.350.10 356 418 7.8E-9 T 11-10-2018 IPR036779 LysM domain superfamily UP12_12330 3675104e0c3ed85e4e8deac38f781268 418 Pfam PF01476 LysM domain 369 411 1.6E-7 T 11-10-2018 IPR018392 LysM domain UP12_12330 3675104e0c3ed85e4e8deac38f781268 418 SMART SM00257 367 411 9.7E-7 T 11-10-2018 IPR018392 LysM domain UP12_12330 3675104e0c3ed85e4e8deac38f781268 418 SUPERFAMILY SSF54106 366 411 2.49E-6 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.3E-27 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 1.3E-27 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.3E-27 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 1.3E-27 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.3E-27 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 9.9E-18 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 9.9E-18 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 9.9E-18 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 9.9E-18 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 401 9.9E-18 T 11-10-2018 UP12_10705 b60580c92edeb116f9011665a2776041 442 Gene3D G3DSA:3.50.50.60 114 439 2.0E-163 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10705 b60580c92edeb116f9011665a2776041 442 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 328 431 7.6E-15 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UP12_10705 b60580c92edeb116f9011665a2776041 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 291 4.2E-66 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_10705 b60580c92edeb116f9011665a2776041 442 Gene3D G3DSA:3.50.50.60 2 339 2.0E-163 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_10705 b60580c92edeb116f9011665a2776041 442 SUPERFAMILY SSF55424 322 440 1.36E-30 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_10705 b60580c92edeb116f9011665a2776041 442 SUPERFAMILY SSF51905 1 315 1.44E-44 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_03555 33b5cdb59a3577f79e3e702707b95c13 335 Gene3D G3DSA:3.90.1200.10 114 313 1.2E-22 T 11-10-2018 UP12_03555 33b5cdb59a3577f79e3e702707b95c13 335 Pfam PF01636 Phosphotransferase enzyme family 29 239 1.2E-28 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase UP12_03555 33b5cdb59a3577f79e3e702707b95c13 335 Gene3D G3DSA:3.30.200.20 1 100 4.7E-6 T 11-10-2018 UP12_03555 33b5cdb59a3577f79e3e702707b95c13 335 SUPERFAMILY SSF56112 16 307 1.6E-54 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_15420 da2215d6be6431e4a92d85cead397978 114 Gene3D G3DSA:3.30.1050.10 3 103 1.3E-7 T 11-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UP12_15420 da2215d6be6431e4a92d85cead397978 114 SUPERFAMILY SSF55718 50 109 1.37E-6 T 11-10-2018 IPR036527 SCP2 sterol-binding domain superfamily UP12_15420 da2215d6be6431e4a92d85cead397978 114 Pfam PF02036 SCP-2 sterol transfer family 26 102 1.3E-6 T 11-10-2018 IPR003033 SCP2 sterol-binding domain UP12_02090 e2fe9280927590e58f37aadddfd67361 497 Gene3D G3DSA:1.20.1250.20 1 497 1.4E-146 T 11-10-2018 UP12_02090 e2fe9280927590e58f37aadddfd67361 497 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 158 170 - T 11-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 UP12_02090 e2fe9280927590e58f37aadddfd67361 497 Pfam PF00854 POT family 97 464 2.1E-79 T 11-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 UP12_02090 e2fe9280927590e58f37aadddfd67361 497 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 493 4.4E-137 T 11-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 UP12_02090 e2fe9280927590e58f37aadddfd67361 497 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 84 108 - T 11-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 UP12_02090 e2fe9280927590e58f37aadddfd67361 497 SUPERFAMILY SSF103473 16 307 1.05E-23 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_02090 e2fe9280927590e58f37aadddfd67361 497 SUPERFAMILY SSF103473 222 491 6.02E-9 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_19295 b89a6f75e38c1f5a8c11516f334d7645 471 Pfam PF10140 WXG100 protein secretion system (Wss), protein YukC 27 240 2.6E-13 T 11-10-2018 IPR018778 Type VII secretion system EssB UP12_19295 b89a6f75e38c1f5a8c11516f334d7645 471 Gene3D G3DSA:1.10.510.10 22 196 7.7E-13 T 11-10-2018 UP12_11755 f4ef602ae82863065c847b1ff16e6bc9 234 SMART SM01007 7 197 1.0E-65 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal UP12_11755 f4ef602ae82863065c847b1ff16e6bc9 234 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 196 1.9E-44 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal UP12_11755 f4ef602ae82863065c847b1ff16e6bc9 234 SUPERFAMILY SSF53639 1 222 6.08E-69 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UP12_11755 f4ef602ae82863065c847b1ff16e6bc9 234 Gene3D G3DSA:3.40.225.10 1 230 1.0E-60 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily UP12_15320 d9d68b817956a22c6c3c8a99dc57c73a 142 Hamap MF_01048 Protein PsiE [psiE]. 2 137 23.678 T 11-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 UP12_15320 d9d68b817956a22c6c3c8a99dc57c73a 142 Pfam PF06146 Phosphate-starvation-inducible E 59 124 5.2E-16 T 11-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like UP12_15320 d9d68b817956a22c6c3c8a99dc57c73a 142 PIRSF PIRSF029598 1 142 2.5E-47 T 11-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 UP12_05365 7706d64849adf2afd5e83b77f1f5514c 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 2.5E-31 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF UP12_04165 36f766deb7f7d6cba62e1e61879aed11 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.8E-21 T 11-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 UP12_04165 36f766deb7f7d6cba62e1e61879aed11 104 Gene3D G3DSA:1.10.3730.20 1 104 6.0E-21 T 11-10-2018 UP12_04165 36f766deb7f7d6cba62e1e61879aed11 104 SUPERFAMILY SSF103481 4 102 1.7E-14 T 11-10-2018 UP12_00955 abe5da1898066aa97712c1d165fb6e56 254 SUPERFAMILY SSF88713 33 243 6.92E-51 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_00955 abe5da1898066aa97712c1d165fb6e56 254 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 53 243 1.0E-78 T 11-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB UP12_00955 abe5da1898066aa97712c1d165fb6e56 254 Pfam PF01522 Polysaccharide deacetylase 52 175 3.8E-24 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_00955 abe5da1898066aa97712c1d165fb6e56 254 Gene3D G3DSA:3.20.20.370 47 254 5.2E-56 T 11-10-2018 UP12_16540 eba403897e9f89e71eb52dda0535352f 74 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 1.0E-17 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 UP12_16540 eba403897e9f89e71eb52dda0535352f 74 Pfam PF02599 Global regulator protein family 1 53 3.8E-26 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 UP12_16540 eba403897e9f89e71eb52dda0535352f 74 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 68 4.1E-32 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 UP12_16540 eba403897e9f89e71eb52dda0535352f 74 Gene3D G3DSA:3.30.70.1680 1 63 2.1E-30 T 11-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 UP12_16540 eba403897e9f89e71eb52dda0535352f 74 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 68 17.886 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 UP12_16540 eba403897e9f89e71eb52dda0535352f 74 SUPERFAMILY SSF117130 1 55 5.75E-21 T 11-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 UP12_16250 7243a7ad4941fec900209547165c8aca 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 7.5E-122 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UP12_16250 7243a7ad4941fec900209547165c8aca 252 SUPERFAMILY SSF51366 1 252 1.96E-80 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_16250 7243a7ad4941fec900209547165c8aca 252 Pfam PF00977 Histidine biosynthesis protein 5 235 4.2E-86 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 UP12_16250 7243a7ad4941fec900209547165c8aca 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 48.711 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UP12_16250 7243a7ad4941fec900209547165c8aca 252 Gene3D G3DSA:3.20.20.70 1 252 2.5E-105 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 150 163 3.8E-43 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 166 179 3.8E-43 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 194 203 3.8E-43 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 110 128 3.8E-43 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 85 96 3.8E-43 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 131 147 3.8E-43 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 2 313 47.555 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 311 1.0E-147 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 Gene3D G3DSA:3.90.226.10 1 312 1.3E-116 T 11-10-2018 UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 SUPERFAMILY SSF52096 3 310 5.51E-94 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_05950 372360d0e10100ed0a0fad9f647a86af 313 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3 145 4.0E-63 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_16295 cd73172dd806c20d6fd277502ba85ed6 213 Pfam PF13460 NAD(P)H-binding 7 195 2.4E-24 T 11-10-2018 IPR016040 NAD(P)-binding domain UP12_16295 cd73172dd806c20d6fd277502ba85ed6 213 SUPERFAMILY SSF51735 1 210 7.06E-32 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16295 cd73172dd806c20d6fd277502ba85ed6 213 Gene3D G3DSA:3.40.50.720 1 211 1.2E-51 T 11-10-2018 UP12_07755 20eb19143cf4b2f274abc90268a7ad47 77 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 55 76 7.0E-5 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 UP12_07755 20eb19143cf4b2f274abc90268a7ad47 77 SUPERFAMILY SSF47336 2 76 4.32E-23 T 11-10-2018 IPR036736 ACP-like superfamily UP12_07755 20eb19143cf4b2f274abc90268a7ad47 77 Pfam PF00550 Phosphopantetheine attachment site 7 73 1.9E-14 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_07755 20eb19143cf4b2f274abc90268a7ad47 77 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 77 2.6E-35 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 UP12_07755 20eb19143cf4b2f274abc90268a7ad47 77 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.757 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 UP12_07755 20eb19143cf4b2f274abc90268a7ad47 77 Gene3D G3DSA:1.10.1200.10 1 77 6.0E-29 T 11-10-2018 IPR036736 ACP-like superfamily UP12_07755 20eb19143cf4b2f274abc90268a7ad47 77 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site UP12_13805 fe64e843155db3a1a6e6c9e398e86cdf 263 Pfam PF01987 Mitochondrial biogenesis AIM24 17 202 3.0E-19 T 11-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 UP12_13805 fe64e843155db3a1a6e6c9e398e86cdf 263 Gene3D G3DSA:3.60.160.10 5 199 3.4E-13 T 11-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily UP12_13805 fe64e843155db3a1a6e6c9e398e86cdf 263 SUPERFAMILY SSF51219 11 216 4.45E-33 T 11-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily UP12_00990 4cc2a1914b35b10db8fa8c3f31495128 321 Pfam PF01758 Sodium Bile acid symporter family 42 214 1.1E-17 T 11-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 UP12_00990 4cc2a1914b35b10db8fa8c3f31495128 321 Gene3D G3DSA:1.20.1530.20 6 313 2.9E-54 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily UP12_18185 f9823be363be2baeb392dce00f57ffe1 87 Pfam PF17279 Family of unknown function (DUF5344) 1 86 1.8E-26 T 11-10-2018 UP12_18185 f9823be363be2baeb392dce00f57ffe1 87 ProDom PD061728 YWQI YWQIA COIL COILED 4 85 6.0E-19 T 11-10-2018 IPR020299 Uncharacterised protein family YwqI UP12_01015 6a34a8f50a4fd7fcad25b4bab78e34fd 289 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 76 4.4E-23 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_01015 6a34a8f50a4fd7fcad25b4bab78e34fd 289 SUPERFAMILY SSF46689 6 77 3.4E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_01015 6a34a8f50a4fd7fcad25b4bab78e34fd 289 SUPERFAMILY SSF53697 94 279 1.05E-41 T 11-10-2018 UP12_01015 6a34a8f50a4fd7fcad25b4bab78e34fd 289 Gene3D G3DSA:3.40.50.10490 94 282 4.8E-48 T 11-10-2018 UP12_01015 6a34a8f50a4fd7fcad25b4bab78e34fd 289 Gene3D G3DSA:1.10.10.10 1 83 3.7E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01015 6a34a8f50a4fd7fcad25b4bab78e34fd 289 Pfam PF01380 SIS domain 127 256 9.1E-25 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_15295 5f606696d082b1828f545965adbc87cd 345 Gene3D G3DSA:1.10.3470.10 19 345 1.4E-96 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15295 5f606696d082b1828f545965adbc87cd 345 Pfam PF01032 FecCD transport family 35 340 4.6E-87 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_15295 5f606696d082b1828f545965adbc87cd 345 SUPERFAMILY SSF81345 14 341 1.44E-83 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_03695 45038499180585c32fe42627042f0ddd 159 Gene3D G3DSA:3.90.960.10 2 156 4.0E-39 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UP12_03695 45038499180585c32fe42627042f0ddd 159 Pfam PF04073 Aminoacyl-tRNA editing domain 27 145 1.9E-30 T 11-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 UP12_03695 45038499180585c32fe42627042f0ddd 159 SUPERFAMILY SSF55826 5 155 5.49E-33 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 UP12_14640 fd7885a56f28bc8c26f6a1e3a87ba523 437 Pfam PF17288 Terminase RNAseH like domain 271 413 1.1E-39 T 11-10-2018 IPR035413 Phage terminase large subunit, C-terminal UP12_14640 fd7885a56f28bc8c26f6a1e3a87ba523 437 Gene3D G3DSA:3.40.50.300 8 235 3.8E-56 T 11-10-2018 UP12_14640 fd7885a56f28bc8c26f6a1e3a87ba523 437 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 22 421 6.0E-98 T 11-10-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 UP12_14640 fd7885a56f28bc8c26f6a1e3a87ba523 437 Gene3D G3DSA:3.30.420.280 241 418 9.4E-33 T 11-10-2018 UP12_14640 fd7885a56f28bc8c26f6a1e3a87ba523 437 Pfam PF04466 Phage terminase large subunit 21 233 1.8E-77 T 11-10-2018 IPR035412 Phage terminase large subunit, N-terminal UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 PIRSF PIRSF004749 1 160 5.8E-51 T 11-10-2018 IPR023635 Peptide deformylase UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 Gene3D G3DSA:3.90.45.10 1 156 1.8E-57 T 11-10-2018 IPR036821 Peptide deformylase superfamily UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 SUPERFAMILY SSF56420 2 154 5.63E-54 T 11-10-2018 IPR036821 Peptide deformylase superfamily UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 PRINTS PR01576 Peptide deformylase signature 33 62 2.9E-35 T 11-10-2018 IPR023635 Peptide deformylase UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 PRINTS PR01576 Peptide deformylase signature 119 148 2.9E-35 T 11-10-2018 IPR023635 Peptide deformylase UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 PRINTS PR01576 Peptide deformylase signature 88 99 2.9E-35 T 11-10-2018 IPR023635 Peptide deformylase UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 PRINTS PR01576 Peptide deformylase signature 100 118 2.9E-35 T 11-10-2018 IPR023635 Peptide deformylase UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 Hamap MF_00163 Peptide deformylase [def]. 2 158 29.147 T 11-10-2018 IPR023635 Peptide deformylase UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 Pfam PF01327 Polypeptide deformylase 3 148 5.7E-49 T 11-10-2018 IPR023635 Peptide deformylase UP12_07655 3d36a91477ea9f04e0bd7b6e61ecd001 160 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 158 1.1E-51 T 11-10-2018 IPR023635 Peptide deformylase UP12_00250 72714cc7d59fcf5bc0003a3f27e4a7ee 94 SMART SM00966 8 51 6.6E-10 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_00250 72714cc7d59fcf5bc0003a3f27e4a7ee 94 SUPERFAMILY SSF89447 1 52 1.23E-16 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily UP12_00250 72714cc7d59fcf5bc0003a3f27e4a7ee 94 Gene3D G3DSA:2.10.260.10 1 51 1.4E-26 T 11-10-2018 UP12_00250 72714cc7d59fcf5bc0003a3f27e4a7ee 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 8.8E-12 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_00250 72714cc7d59fcf5bc0003a3f27e4a7ee 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 4.6E-11 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_16255 ff8bc6245bfe488ab6cce8653403e65b 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 6 237 7.2E-85 T 11-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 UP12_16255 ff8bc6245bfe488ab6cce8653403e65b 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 5 241 37.082 T 11-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 UP12_16255 ff8bc6245bfe488ab6cce8653403e65b 245 Pfam PF00977 Histidine biosynthesis protein 6 234 3.5E-77 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 UP12_16255 ff8bc6245bfe488ab6cce8653403e65b 245 SUPERFAMILY SSF51366 5 240 7.69E-71 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_16255 ff8bc6245bfe488ab6cce8653403e65b 245 Gene3D G3DSA:3.20.20.70 1 243 4.2E-89 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.371 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 8.9E-20 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 Gene3D G3DSA:3.40.50.620 1 160 1.0E-60 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_07280 db47d435bb7e917c6573ab196dabe545 160 SUPERFAMILY SSF52374 4 157 1.24E-44 T 11-10-2018 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 1.8E-64 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 Pfam PF01467 Cytidylyltransferase-like 7 134 2.1E-20 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 78 3.0E-5 T 11-10-2018 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 2.4E-54 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 2.4E-54 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 2.4E-54 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 2.4E-54 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UP12_07280 db47d435bb7e917c6573ab196dabe545 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 2.4E-54 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 UP12_19155 8539c06f84f6d8f80354a13d5c014eac 239 SUPERFAMILY SSF53335 1 237 9.78E-50 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_19155 8539c06f84f6d8f80354a13d5c014eac 239 Gene3D G3DSA:3.40.50.150 1 239 2.1E-86 T 11-10-2018 UP12_19155 8539c06f84f6d8f80354a13d5c014eac 239 Pfam PF02527 rRNA small subunit methyltransferase G 21 202 8.8E-58 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UP12_19155 8539c06f84f6d8f80354a13d5c014eac 239 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 217 5.3E-51 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UP12_19155 8539c06f84f6d8f80354a13d5c014eac 239 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 214 28.114 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UP12_19155 8539c06f84f6d8f80354a13d5c014eac 239 PIRSF PIRSF003078 1 220 2.5E-57 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 SUPERFAMILY SSF55979 133 251 1.17E-28 T 11-10-2018 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 PIRSF PIRSF000804 1 378 1.2E-120 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 127 1.4E-40 T 11-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 SMART SM00480 17 373 4.4E-180 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 1.3E-39 T 11-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 SUPERFAMILY SSF55979 254 377 5.34E-32 T 11-10-2018 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 1.3E-135 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 SUPERFAMILY SSF55979 1 127 6.28E-23 T 11-10-2018 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 Gene3D G3DSA:3.70.10.10 145 375 9.6E-143 T 11-10-2018 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 136 251 3.4E-40 T 11-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 UP12_00010 88c13069cf1bdc77493db23b1650b0d3 378 Gene3D G3DSA:3.10.150.10 1 250 9.6E-143 T 11-10-2018 UP12_13540 2c5cedaee5300b2d95241e8edbe5eb32 432 Pfam PF00860 Permease family 14 392 1.5E-67 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 UP12_13540 2c5cedaee5300b2d95241e8edbe5eb32 432 PIRSF PIRSF005353 1 432 6.3E-173 T 11-10-2018 IPR026033 Purine permease PbuG-like UP12_02950 45c5e393ea22ba937c20ad8e5bb641ac 343 Pfam PF01757 Acyltransferase family 8 316 2.5E-15 T 11-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UP12_16735 3ff58dff214085f29b08b9e26d57bb65 256 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 2 239 54.598 T 11-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 UP12_16735 3ff58dff214085f29b08b9e26d57bb65 256 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 230 1.9E-71 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 UP12_16735 3ff58dff214085f29b08b9e26d57bb65 256 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 224 3.0E-59 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 UP12_15840 0e9f5144c6a4b3ebd8154a45f1465ef9 106 Gene3D G3DSA:1.10.10.10 2 106 2.2E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15840 0e9f5144c6a4b3ebd8154a45f1465ef9 106 SUPERFAMILY SSF46785 2 102 1.63E-29 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_15840 0e9f5144c6a4b3ebd8154a45f1465ef9 106 Pfam PF01638 HxlR-like helix-turn-helix 16 103 9.0E-32 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_05815 6808ef3fe498ea42fe7473aba92ca2de 205 Gene3D G3DSA:3.20.20.70 1 204 7.3E-55 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_05815 6808ef3fe498ea42fe7473aba92ca2de 205 Pfam PF02581 Thiamine monophosphate synthase 4 179 5.5E-42 T 11-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_05815 6808ef3fe498ea42fe7473aba92ca2de 205 SUPERFAMILY SSF51391 3 196 1.06E-46 T 11-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17780 3ccc990b00ef8de39ca8f22408cb34cc 333 SUPERFAMILY SSF51679 1 329 6.41E-75 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_17780 3ccc990b00ef8de39ca8f22408cb34cc 333 Pfam PF00296 Luciferase-like monooxygenase 14 302 4.1E-42 T 11-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 UP12_17780 3ccc990b00ef8de39ca8f22408cb34cc 333 Gene3D G3DSA:3.20.20.30 1 333 1.4E-100 T 11-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 UP12_17780 3ccc990b00ef8de39ca8f22408cb34cc 333 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 330 4.6E-117 T 11-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 UP12_04215 ad1c3e5101bbae5b12fb56c32603cd1e 108 SUPERFAMILY SSF103481 8 106 2.62E-10 T 11-10-2018 UP12_04215 ad1c3e5101bbae5b12fb56c32603cd1e 108 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 2 107 21.813 T 11-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 UP12_04215 ad1c3e5101bbae5b12fb56c32603cd1e 108 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 1 108 3.7E-45 T 11-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 UP12_16080 39866693b69c0a76da43c6133ba45ac4 333 SUPERFAMILY SSF81345 4 331 7.06E-80 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_16080 39866693b69c0a76da43c6133ba45ac4 333 Gene3D G3DSA:1.10.3470.10 3 333 1.1E-94 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_16080 39866693b69c0a76da43c6133ba45ac4 333 Pfam PF01032 FecCD transport family 19 331 5.1E-89 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_12640 dda9c5198ab8d948759c66177d5d13e4 207 TIGRFAM TIGR01543 proheadase_HK97: phage prohead protease, HK97 family 26 172 7.5E-21 T 11-10-2018 IPR006433 Prohead protease UP12_12640 dda9c5198ab8d948759c66177d5d13e4 207 Pfam PF04586 Caudovirus prohead serine protease 11 182 1.5E-39 T 11-10-2018 IPR006433 Prohead protease UP12_17740 fb4fd4e212d66a55991b14c153296f23 269 Gene3D G3DSA:3.40.1190.20 1 269 1.2E-92 T 11-10-2018 IPR029056 Ribokinase-like UP12_17740 fb4fd4e212d66a55991b14c153296f23 269 Pfam PF08543 Phosphomethylpyrimidine kinase 13 260 4.4E-87 T 11-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 UP12_17740 fb4fd4e212d66a55991b14c153296f23 269 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 262 2.5E-85 T 11-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17740 fb4fd4e212d66a55991b14c153296f23 269 SUPERFAMILY SSF53613 1 263 7.33E-76 T 11-10-2018 IPR029056 Ribokinase-like UP12_13035 8002c662078f3baf283dfb5f82f12058 126 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 1.9E-34 T 11-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 UP12_13035 8002c662078f3baf283dfb5f82f12058 126 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 31.087 T 11-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 UP12_13035 8002c662078f3baf283dfb5f82f12058 126 Gene3D G3DSA:3.30.160.750 63 125 4.4E-17 T 11-10-2018 UP12_13035 8002c662078f3baf283dfb5f82f12058 126 Gene3D G3DSA:3.30.360.110 1 62 2.3E-25 T 11-10-2018 UP12_13035 8002c662078f3baf283dfb5f82f12058 126 SUPERFAMILY SSF56276 3 113 4.32E-39 T 11-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 UP12_13035 8002c662078f3baf283dfb5f82f12058 126 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 2.2E-39 T 11-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 UP12_08335 909434ecb269ced7b3516b07a20ae7c7 368 Pfam PF13020 Domain of unknown function (DUF3883) 245 338 1.5E-16 T 11-10-2018 IPR024975 Domain of unknown function DUF3883 UP12_08335 909434ecb269ced7b3516b07a20ae7c7 368 Pfam PF12102 Domain of unknown function (DUF3578) 19 194 6.0E-22 T 11-10-2018 IPR021961 Protein of unknown function DUF3578 UP12_08335 909434ecb269ced7b3516b07a20ae7c7 368 Gene3D G3DSA:3.30.920.90 33 218 1.5E-6 T 11-10-2018 UP12_08685 a8e6e6022081c31b313e9b2c6174999d 103 Pfam PF01476 LysM domain 39 88 2.0E-8 T 11-10-2018 IPR018392 LysM domain UP12_08685 a8e6e6022081c31b313e9b2c6174999d 103 Hamap MF_02014 Cell division suppressor protein YneA [yneA]. 2 102 27.745 T 11-10-2018 IPR022887 Cell division suppressor protein, YneA UP12_08685 a8e6e6022081c31b313e9b2c6174999d 103 SMART SM00257 37 88 4.3E-5 T 11-10-2018 IPR018392 LysM domain UP12_08685 a8e6e6022081c31b313e9b2c6174999d 103 SUPERFAMILY SSF54106 39 89 3.79E-5 T 11-10-2018 UP12_08685 a8e6e6022081c31b313e9b2c6174999d 103 Gene3D G3DSA:3.10.350.10 25 95 6.2E-10 T 11-10-2018 IPR036779 LysM domain superfamily UP12_16045 75ec41917becbbd4b238b604abc55490 379 Pfam PF13477 Glycosyl transferase 4-like 4 146 4.8E-16 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 UP12_16045 75ec41917becbbd4b238b604abc55490 379 Pfam PF00534 Glycosyl transferases group 1 185 349 7.4E-42 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 UP12_16045 75ec41917becbbd4b238b604abc55490 379 Gene3D G3DSA:3.40.50.2000 171 355 2.5E-76 T 11-10-2018 UP12_16045 75ec41917becbbd4b238b604abc55490 379 SUPERFAMILY SSF53756 19 368 5.89E-77 T 11-10-2018 UP12_16045 75ec41917becbbd4b238b604abc55490 379 Gene3D G3DSA:3.40.50.2000 26 368 2.5E-76 T 11-10-2018 UP12_02250 4619b30eabd31975e1f89c1e42a4362a 252 SUPERFAMILY SSF88713 3 251 1.04E-99 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_02250 4619b30eabd31975e1f89c1e42a4362a 252 Gene3D G3DSA:3.20.20.370 2 252 1.1E-103 T 11-10-2018 UP12_02250 4619b30eabd31975e1f89c1e42a4362a 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 46.191 T 11-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 UP12_02250 4619b30eabd31975e1f89c1e42a4362a 252 Pfam PF03746 LamB/YcsF family 4 241 4.1E-103 T 11-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 UP12_07095 097c9dbdd79c7707f6ca52a013e42c45 89 SUPERFAMILY SSF158504 4 85 2.22E-33 T 11-10-2018 IPR023324 BH2638-like superfamily UP12_07095 097c9dbdd79c7707f6ca52a013e42c45 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 89 1.0E-26 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 UP12_07095 097c9dbdd79c7707f6ca52a013e42c45 89 Hamap MF_01041 UPF0223 protein . 1 89 25.751 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 UP12_07095 097c9dbdd79c7707f6ca52a013e42c45 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 85 1.9E-37 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 UP12_07095 097c9dbdd79c7707f6ca52a013e42c45 89 PIRSF PIRSF037260 1 89 1.2E-37 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 UP12_07095 097c9dbdd79c7707f6ca52a013e42c45 89 Gene3D G3DSA:1.10.220.80 12 89 1.3E-29 T 11-10-2018 IPR023324 BH2638-like superfamily UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 Gene3D G3DSA:3.30.1360.40 68 149 1.9E-33 T 11-10-2018 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 6.3E-57 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 SUPERFAMILY SSF46785 5 78 2.47E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 9.0E-27 T 11-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 9.5E-32 T 11-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 3.0E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 3.0E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 3.0E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 3.0E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 71.747 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 Gene3D G3DSA:1.10.10.10 4 67 3.3E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 SUPERFAMILY SSF55252 80 148 7.06E-22 T 11-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 UP12_10955 5c05c80333a8752caaabc0cd964e385e 149 Pfam PF02863 Arginine repressor, C-terminal domain 81 145 7.2E-27 T 11-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 SUPERFAMILY SSF109709 106 216 1.26E-36 T 11-10-2018 UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 Pfam PF08535 KorB domain 136 215 2.0E-5 T 11-10-2018 IPR013741 Repressor KorB domain UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 SMART SM00470 24 113 4.3E-38 T 11-10-2018 IPR003115 ParB/Sulfiredoxin UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 Gene3D G3DSA:1.10.10.2830 101 214 2.4E-38 T 11-10-2018 UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 SUPERFAMILY SSF110849 24 115 7.85E-28 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 20 198 1.9E-68 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 Pfam PF02195 ParB-like nuclease domain 24 112 2.7E-27 T 11-10-2018 IPR003115 ParB/Sulfiredoxin UP12_19135 68c2ea466e87b88b6b11f607b88ab8b7 284 Gene3D G3DSA:3.90.1530.30 37 99 5.9E-29 T 11-10-2018 UP12_15585 6dfda6188ecd1ab0fd816509b93cb24c 316 Gene3D G3DSA:3.40.50.1980 61 181 3.9E-38 T 11-10-2018 UP12_15585 6dfda6188ecd1ab0fd816509b93cb24c 316 SUPERFAMILY SSF53807 39 313 1.84E-67 T 11-10-2018 UP12_15585 6dfda6188ecd1ab0fd816509b93cb24c 316 Pfam PF01497 Periplasmic binding protein 64 288 4.4E-38 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_15585 6dfda6188ecd1ab0fd816509b93cb24c 316 Gene3D G3DSA:3.40.50.1980 184 313 3.2E-42 T 11-10-2018 UP12_16060 6c801480a2efd6d09f90e9d971a4f356 243 Pfam PF02706 Chain length determinant protein 4 91 5.6E-16 T 11-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 UP12_06885 d427649c700b9b0a5a412d2be48410bd 268 Pfam PF00924 Mechanosensitive ion channel 68 259 4.1E-48 T 11-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 UP12_06885 d427649c700b9b0a5a412d2be48410bd 268 SUPERFAMILY SSF50182 111 169 1.34E-15 T 11-10-2018 IPR010920 LSM domain superfamily UP12_06885 d427649c700b9b0a5a412d2be48410bd 268 Gene3D G3DSA:3.30.70.100 176 262 5.1E-23 T 11-10-2018 UP12_06885 d427649c700b9b0a5a412d2be48410bd 268 SUPERFAMILY SSF82689 174 259 2.35E-10 T 11-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 UP12_06885 d427649c700b9b0a5a412d2be48410bd 268 Gene3D G3DSA:2.30.30.60 126 175 2.5E-22 T 11-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily UP12_06885 d427649c700b9b0a5a412d2be48410bd 268 SUPERFAMILY SSF82861 22 109 3.92E-15 T 11-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 Gene3D G3DSA:3.40.50.1980 392 539 1.6E-20 T 11-10-2018 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 SMART SM00342 191 274 1.8E-29 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 Gene3D G3DSA:1.10.10.60 176 228 3.4E-13 T 11-10-2018 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 258 3.7E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 274 3.7E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 Gene3D G3DSA:3.40.50.1980 271 389 3.8E-9 T 11-10-2018 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 Gene3D G3DSA:1.10.10.2730 229 270 6.4E-16 T 11-10-2018 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 SUPERFAMILY SSF53807 271 534 2.28E-33 T 11-10-2018 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 Pfam PF12833 Helix-turn-helix domain 197 275 2.1E-20 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 Pfam PF01497 Periplasmic binding protein 306 517 4.7E-17 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 SUPERFAMILY SSF46689 176 225 2.69E-7 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 SUPERFAMILY SSF46689 228 278 4.93E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_19005 0e4182c9a9a39011cae1025b0cbf3a2b 540 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 228 270 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 UP12_02585 d196560db844e05a57c1e09a1b1334a6 199 SUPERFAMILY SSF81606 19 195 3.14E-14 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02585 d196560db844e05a57c1e09a1b1334a6 199 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 35 158 2.1E-12 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02585 d196560db844e05a57c1e09a1b1334a6 199 SMART SM00332 6 196 0.0086 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02585 d196560db844e05a57c1e09a1b1334a6 199 Gene3D G3DSA:3.60.40.10 1 199 1.0E-44 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_02585 d196560db844e05a57c1e09a1b1334a6 199 SMART SM00331 9 198 2.8E-40 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 SUPERFAMILY SSF55021 21 101 4.25E-20 T 11-10-2018 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 299 47.073 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 Pfam PF00551 Formyl transferase 104 281 1.0E-41 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 SUPERFAMILY SSF53328 104 300 2.75E-60 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 Pfam PF01842 ACT domain 22 83 2.2E-9 T 11-10-2018 IPR002912 ACT domain UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 9.3E-63 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 9.3E-63 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 9.3E-63 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 9.3E-63 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 9.3E-63 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 9.3E-63 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 299 2.7E-131 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 Gene3D G3DSA:3.40.50.170 104 300 5.2E-72 T 11-10-2018 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 PIRSF PIRSF036480 17 300 1.7E-114 T 11-10-2018 UP12_06370 716c6f523a2ab8825996a9d2f59750bd 300 Gene3D G3DSA:3.30.70.260 16 102 6.9E-28 T 11-10-2018 UP12_02515 8a61a9322f921d8b442b91a8244521d9 499 Pfam PF03703 Bacterial PH domain 411 491 2.8E-7 T 11-10-2018 IPR005182 Domain of unknown function DUF304 UP12_02515 8a61a9322f921d8b442b91a8244521d9 499 Pfam PF03703 Bacterial PH domain 263 346 2.2E-14 T 11-10-2018 IPR005182 Domain of unknown function DUF304 UP12_02515 8a61a9322f921d8b442b91a8244521d9 499 Pfam PF03703 Bacterial PH domain 67 146 9.2E-20 T 11-10-2018 IPR005182 Domain of unknown function DUF304 UP12_02515 8a61a9322f921d8b442b91a8244521d9 499 PIRSF PIRSF026631 1 499 2.9E-132 T 11-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 UP12_11270 615067980347415920fe6abb6065bf82 186 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 179 1.1E-55 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase UP12_11270 615067980347415920fe6abb6065bf82 186 Gene3D G3DSA:3.40.50.10420 1 186 3.0E-63 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily UP12_11270 615067980347415920fe6abb6065bf82 186 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 179 1.8E-52 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase UP12_11270 615067980347415920fe6abb6065bf82 186 SUPERFAMILY SSF100950 1 184 8.65E-54 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_11270 615067980347415920fe6abb6065bf82 186 PIRSF PIRSF006806 1 182 3.3E-52 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase UP12_13875 1858bb94e1e5641c01ed38a52edfc14c 350 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 10 339 1.9E-37 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 Pfam PF07730 Histidine kinase 184 248 1.8E-17 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 374 1.4E-6 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 Gene3D G3DSA:3.30.565.10 243 379 1.2E-24 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 SMART SM00065 26 177 8.8E-5 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 SUPERFAMILY SSF55781 29 172 3.93E-18 T 11-10-2018 UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 SUPERFAMILY SSF55874 253 372 1.7E-16 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 Gene3D G3DSA:3.30.450.40 2 180 6.2E-22 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_04810 de0a06e3adde0c17d4d314baf405c6e6 381 Pfam PF13185 GAF domain 26 168 1.1E-11 T 11-10-2018 IPR003018 GAF domain GO:0005515 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 SMART SM00422 4 73 2.3E-21 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 Pfam PF13411 MerR HTH family regulatory protein 6 72 1.3E-16 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 1.0E-8 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 1.0E-8 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 1.0E-8 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 Gene3D G3DSA:1.10.1660.10 2 117 3.1E-28 T 11-10-2018 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 ProSitePatterns PS00552 MerR-type HTH domain signature. 7 29 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_18435 02f6c00529b91103a56cb0549fe15b31 119 SUPERFAMILY SSF46955 4 111 4.03E-26 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 Pfam PF00176 SNF2 family N-terminal domain 443 734 6.7E-59 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 SMART SM00487 446 633 5.3E-34 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 Pfam PF12419 SNF2 Helicase protein 266 392 1.8E-35 T 11-10-2018 IPR022138 Helicase SWF/SNF-related UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 Pfam PF00271 Helicase conserved C-terminal domain 753 863 2.8E-20 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 SUPERFAMILY SSF52540 434 664 4.39E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 SUPERFAMILY SSF52540 669 920 1.88E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 Gene3D G3DSA:1.20.120.850 688 912 8.4E-87 T 11-10-2018 UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 Gene3D G3DSA:3.40.50.300 674 877 8.4E-87 T 11-10-2018 UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 SMART SM00490 780 863 2.5E-21 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_16960 d799cbdf82c9662955f40c4fb498bb5d 925 Gene3D G3DSA:3.40.50.10810 451 665 1.4E-69 T 11-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily UP12_02305 5ef54a44e1540d4526c162784206afb9 289 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 55 284 4.7E-62 T 11-10-2018 UP12_02305 5ef54a44e1540d4526c162784206afb9 289 SUPERFAMILY SSF51735 44 287 1.16E-81 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02305 5ef54a44e1540d4526c162784206afb9 289 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 181 209 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 182 1.7E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 133 1.7E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 213 1.7E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 7.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 7.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 133 7.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 249 269 7.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 7.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 184 7.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02305 5ef54a44e1540d4526c162784206afb9 289 Gene3D G3DSA:3.40.50.720 2 287 5.5E-88 T 11-10-2018 UP12_07490 e5ace89b854d274b75d7e4a779693fa7 152 Gene3D G3DSA:3.30.110.150 58 152 7.3E-37 T 11-10-2018 IPR038594 SepF-like superfamily UP12_07490 e5ace89b854d274b75d7e4a779693fa7 152 Pfam PF04472 Cell division protein SepF 65 136 4.8E-31 T 11-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 UP12_07490 e5ace89b854d274b75d7e4a779693fa7 152 Hamap MF_01197 Cell division protein SepF [sepF]. 1 144 21.085 T 11-10-2018 IPR023052 Cell division protein SepF GO:0090529 UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 245 1.2E-63 T 11-10-2018 UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 Gene3D G3DSA:3.40.50.720 2 250 1.8E-76 T 11-10-2018 UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.7E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.7E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.7E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.7E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.7E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.7E-29 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.9E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.9E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.9E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_04370 041a19930342e99cafc9f8828c4b26c9 250 SUPERFAMILY SSF51735 4 248 1.76E-75 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_09510 5dbeedbb0f8f06d30e1b74e417840c2a 624 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 19 615 3.9E-106 T 11-10-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UP12_09510 5dbeedbb0f8f06d30e1b74e417840c2a 624 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 304 615 1.1E-79 T 11-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UP12_09510 5dbeedbb0f8f06d30e1b74e417840c2a 624 SUPERFAMILY SSF48239 35 291 2.35E-41 T 11-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UP12_09510 5dbeedbb0f8f06d30e1b74e417840c2a 624 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 15 291 9.2E-57 T 11-10-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 UP12_09510 5dbeedbb0f8f06d30e1b74e417840c2a 624 Gene3D G3DSA:1.50.10.20 19 614 1.7E-176 T 11-10-2018 UP12_09510 5dbeedbb0f8f06d30e1b74e417840c2a 624 SUPERFAMILY SSF48239 302 615 1.36E-82 T 11-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid UP12_09510 5dbeedbb0f8f06d30e1b74e417840c2a 624 Gene3D G3DSA:1.50.10.20 33 302 1.7E-176 T 11-10-2018 UP12_17485 785f94369454862db8892951fede9840 270 SUPERFAMILY SSF55486 104 253 6.07E-21 T 11-10-2018 UP12_17485 785f94369454862db8892951fede9840 270 Gene3D G3DSA:3.40.390.10 91 265 2.4E-15 T 11-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 UP12_17485 785f94369454862db8892951fede9840 270 Pfam PF13688 Metallo-peptidase family M12 102 244 8.0E-28 T 11-10-2018 UP12_01460 5fc94b5fb0b4ff8aeee60ee2a628bbfa 276 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 7.8E-60 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_01460 5fc94b5fb0b4ff8aeee60ee2a628bbfa 276 PIRSF PIRSF006483 1 276 2.0E-85 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_01460 5fc94b5fb0b4ff8aeee60ee2a628bbfa 276 Gene3D G3DSA:3.30.70.120 188 263 6.0E-26 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_01460 5fc94b5fb0b4ff8aeee60ee2a628bbfa 276 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 3.5E-22 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 UP12_13375 fb16ed010e10cf665b75ce762aaddaaa 187 Gene3D G3DSA:3.40.50.850 1 185 3.3E-55 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_13375 fb16ed010e10cf665b75ce762aaddaaa 187 SUPERFAMILY SSF52499 4 184 6.54E-46 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_13375 fb16ed010e10cf665b75ce762aaddaaa 187 Pfam PF00857 Isochorismatase family 7 179 8.7E-35 T 11-10-2018 IPR000868 Isochorismatase-like GO:0003824 UP12_13735 46a3f49d98d7fa3be931fb9bd11d1933 632 Pfam PF00733 Asparagine synthase 240 610 2.3E-113 T 11-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 UP12_13735 46a3f49d98d7fa3be931fb9bd11d1933 632 SUPERFAMILY SSF52402 232 605 5.03E-86 T 11-10-2018 UP12_13735 46a3f49d98d7fa3be931fb9bd11d1933 632 SUPERFAMILY SSF56235 1 225 4.29E-62 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_13735 46a3f49d98d7fa3be931fb9bd11d1933 632 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 3.1E-183 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UP12_13735 46a3f49d98d7fa3be931fb9bd11d1933 632 Gene3D G3DSA:3.60.20.10 3 189 1.9E-65 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_13735 46a3f49d98d7fa3be931fb9bd11d1933 632 Pfam PF13537 Glutamine amidotransferase domain 51 168 1.8E-45 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain UP12_13735 46a3f49d98d7fa3be931fb9bd11d1933 632 PIRSF PIRSF001589 1 628 3.3E-198 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 323 4.9E-72 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 277 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 303 310 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 2.4E-68 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 SUPERFAMILY SSF55424 338 456 1.46E-36 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 Gene3D G3DSA:3.30.390.30 341 458 1.8E-39 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 Gene3D G3DSA:3.50.50.60 5 330 1.8E-108 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PIRSF PIRSF000350 1 459 7.2E-95 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 SUPERFAMILY SSF51905 1 332 2.24E-61 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_06230 28368c6cab333991ae97913610e2b6d3 460 Gene3D G3DSA:3.50.50.60 153 276 1.8E-108 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_06230 28368c6cab333991ae97913610e2b6d3 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 450 1.0E-32 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.5E-38 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 288 310 2.5E-38 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 2.5E-38 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 278 2.5E-38 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 2.5E-38 T 11-10-2018 UP12_06230 28368c6cab333991ae97913610e2b6d3 460 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 457 1.4E-162 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 UP12_03045 b2a6e44794af9c9960a8eaecf607d03b 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 260 272 4.6E-7 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UP12_03045 b2a6e44794af9c9960a8eaecf607d03b 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 273 286 4.6E-7 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UP12_03045 b2a6e44794af9c9960a8eaecf607d03b 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 109 119 4.6E-7 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UP12_03045 b2a6e44794af9c9960a8eaecf607d03b 329 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 203 209 4.6E-7 T 11-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 UP12_03045 b2a6e44794af9c9960a8eaecf607d03b 329 SUPERFAMILY SSF51430 1 317 5.76E-96 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_03045 b2a6e44794af9c9960a8eaecf607d03b 329 Gene3D G3DSA:3.20.20.100 1 327 8.9E-113 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_03045 b2a6e44794af9c9960a8eaecf607d03b 329 Pfam PF00248 Aldo/keto reductase family 16 316 1.3E-78 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain UP12_16410 94d0fef19a73f293ed89ad477dd1ff44 327 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 213 281 3.2E-4 T 11-10-2018 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 UP12_16410 94d0fef19a73f293ed89ad477dd1ff44 327 Gene3D G3DSA:2.130.10.10 34 213 2.0E-19 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_16410 94d0fef19a73f293ed89ad477dd1ff44 327 Gene3D G3DSA:2.130.10.10 235 325 1.4E-14 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_16410 94d0fef19a73f293ed89ad477dd1ff44 327 SUPERFAMILY SSF51004 49 323 1.12E-40 T 11-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily UP12_16690 0e7df926e700a3af0769564749e53a35 306 Hamap MF_01140 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU [tagU]. 9 306 47.281 T 11-10-2018 IPR023734 Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU UP12_16690 0e7df926e700a3af0769564749e53a35 306 Gene3D G3DSA:1.10.260.150 47 306 1.8E-89 T 11-10-2018 UP12_16690 0e7df926e700a3af0769564749e53a35 306 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 82 225 3.2E-54 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_16690 0e7df926e700a3af0769564749e53a35 306 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 83 224 3.1E-49 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_06520 b0e1501a6f2cf6adaa2b22afa22f1c88 299 Hamap MF_00188 Protease HtpX [htpX]. 2 299 23.99 T 11-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 UP12_06520 b0e1501a6f2cf6adaa2b22afa22f1c88 299 Gene3D G3DSA:3.30.2010.10 81 173 2.1E-30 T 11-10-2018 UP12_06520 b0e1501a6f2cf6adaa2b22afa22f1c88 299 Pfam PF01435 Peptidase family M48 90 298 1.4E-37 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 9.8E-13 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 9.8E-13 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 9.8E-13 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00097 Anthranilate synthase component II signature 47 56 2.9E-34 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00097 Anthranilate synthase component II signature 99 107 2.9E-34 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00097 Anthranilate synthase component II signature 119 131 2.9E-34 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00097 Anthranilate synthase component II signature 74 85 2.9E-34 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.9E-34 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00097 Anthranilate synthase component II signature 164 177 2.9E-34 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 SUPERFAMILY SSF52317 1 190 1.82E-55 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.6E-7 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.6E-7 T 11-10-2018 UP12_00450 818aa119383c25f620a8f469775d3790 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 1.3E-90 T 11-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_00450 818aa119383c25f620a8f469775d3790 197 Gene3D G3DSA:3.40.50.880 1 190 4.6E-62 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_00450 818aa119383c25f620a8f469775d3790 197 Pfam PF00117 Glutamine amidotransferase class-I 4 185 5.7E-56 T 11-10-2018 IPR017926 Glutamine amidotransferase UP12_03740 e60c5d2ace4e006dd24294ce0a3df959 412 SUPERFAMILY SSF103473 14 401 1.83E-54 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_03740 e60c5d2ace4e006dd24294ce0a3df959 412 Gene3D G3DSA:1.20.1250.20 18 202 1.9E-18 T 11-10-2018 UP12_03740 e60c5d2ace4e006dd24294ce0a3df959 412 Gene3D G3DSA:1.20.1250.20 221 405 5.2E-22 T 11-10-2018 UP12_03740 e60c5d2ace4e006dd24294ce0a3df959 412 Pfam PF07690 Major Facilitator Superfamily 28 367 4.1E-32 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_11730 171e34c416aa2746e8849b1a6493bb35 168 Pfam PF13420 Acetyltransferase (GNAT) domain 3 157 1.3E-14 T 11-10-2018 UP12_11730 171e34c416aa2746e8849b1a6493bb35 168 Gene3D G3DSA:3.40.630.30 1 167 1.6E-40 T 11-10-2018 UP12_11730 171e34c416aa2746e8849b1a6493bb35 168 SUPERFAMILY SSF55729 2 167 5.74E-29 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_09790 f933023b55deaa640b6b44e6df2989eb 175 Gene3D G3DSA:1.10.3760.10 1 165 2.0E-73 T 11-10-2018 UP12_09790 f933023b55deaa640b6b44e6df2989eb 175 SUPERFAMILY SSF101307 5 162 4.84E-50 T 11-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 UP12_09790 f933023b55deaa640b6b44e6df2989eb 175 PIRSF PIRSF019587 4 168 9.6E-71 T 11-10-2018 IPR026038 Putative phosphatidylglycerophosphatase UP12_09790 f933023b55deaa640b6b44e6df2989eb 175 Pfam PF04608 Phosphatidylglycerophosphatase A 23 158 1.8E-18 T 11-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 UP12_00735 a6ceef74d27d22b33c30da925912fc82 95 Pfam PF00276 Ribosomal protein L23 6 88 7.4E-32 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 UP12_00735 a6ceef74d27d22b33c30da925912fc82 95 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 11-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00735 a6ceef74d27d22b33c30da925912fc82 95 Gene3D G3DSA:3.30.70.330 1 95 3.4E-32 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily UP12_00735 a6ceef74d27d22b33c30da925912fc82 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.84 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 UP12_00735 a6ceef74d27d22b33c30da925912fc82 95 SUPERFAMILY SSF54189 2 91 1.26E-30 T 11-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 Gene3D G3DSA:2.40.10.10 62 169 1.1E-23 T 11-10-2018 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 Gene3D G3DSA:2.40.10.10 170 292 2.2E-38 T 11-10-2018 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 SUPERFAMILY SSF50494 74 286 3.04E-53 T 11-10-2018 IPR009003 Peptidase S1, PA clan UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 SUPERFAMILY SSF50156 272 387 7.62E-18 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 Pfam PF13365 Trypsin-like peptidase domain 105 252 5.0E-31 T 11-10-2018 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 PRINTS PR00834 HtrA/DegQ protease family signature 179 203 1.4E-35 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 PRINTS PR00834 HtrA/DegQ protease family signature 336 348 1.4E-35 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 PRINTS PR00834 HtrA/DegQ protease family signature 245 262 1.4E-35 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 PRINTS PR00834 HtrA/DegQ protease family signature 117 129 1.4E-35 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 PRINTS PR00834 HtrA/DegQ protease family signature 138 158 1.4E-35 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 PRINTS PR00834 HtrA/DegQ protease family signature 223 240 1.4E-35 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 Pfam PF13180 PDZ domain 290 387 1.4E-21 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 SMART SM00228 290 378 1.9E-10 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_18870 0170cdf1f75333d960dca743d6eb738d 395 Gene3D G3DSA:2.30.42.10 293 392 3.0E-26 T 11-10-2018 UP12_00575 ef71ace1021786dfea049bfb7e566cb7 363 ProSitePatterns PS00112 Phosphagen kinase active site signature. 167 173 - T 11-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 UP12_00575 ef71ace1021786dfea049bfb7e566cb7 363 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 54 253 1.0E-74 T 11-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 UP12_00575 ef71ace1021786dfea049bfb7e566cb7 363 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 350 40.524 T 11-10-2018 IPR023660 Protein arginine kinase GO:0016775 UP12_00575 ef71ace1021786dfea049bfb7e566cb7 363 Gene3D G3DSA:3.30.590.10 8 264 4.7E-74 T 11-10-2018 UP12_00575 ef71ace1021786dfea049bfb7e566cb7 363 SUPERFAMILY SSF55931 3 268 4.21E-88 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 UP12_13650 1ca47061207edefea0b88d9a5b287009 300 Pfam PF05448 Acetyl xylan esterase (AXE1) 26 188 4.5E-6 T 11-10-2018 IPR008391 Acetyl xylan esterase UP12_13650 1ca47061207edefea0b88d9a5b287009 300 Gene3D G3DSA:3.40.50.1820 2 300 8.8E-61 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13650 1ca47061207edefea0b88d9a5b287009 300 SUPERFAMILY SSF53474 18 300 1.37E-32 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_19585 345326eb29fd5e72effb9a328fa5989a 387 Gene3D G3DSA:1.25.40.10 2 385 7.1E-102 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_19585 345326eb29fd5e72effb9a328fa5989a 387 Pfam PF13424 Tetratricopeptide repeat 191 257 4.2E-9 T 11-10-2018 UP12_19585 345326eb29fd5e72effb9a328fa5989a 387 SMART SM00028 185 218 52.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_19585 345326eb29fd5e72effb9a328fa5989a 387 SMART SM00028 144 177 15.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_19585 345326eb29fd5e72effb9a328fa5989a 387 SMART SM00028 104 137 10.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_19585 345326eb29fd5e72effb9a328fa5989a 387 SMART SM00028 225 258 4.9E-5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_19585 345326eb29fd5e72effb9a328fa5989a 387 SUPERFAMILY SSF48452 106 311 4.67E-23 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.2E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.2E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.2E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.2E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.2E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 Gene3D G3DSA:3.40.50.720 1 238 2.0E-39 T 11-10-2018 UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 SUPERFAMILY SSF51735 2 226 1.0E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 Pfam PF00106 short chain dehydrogenase 3 194 1.9E-32 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.3E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.3E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01255 5e2b8608a64b3c304dbe8b80184d8ba9 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.3E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17875 61ca32d527d1dc51b0f4432185d5208a 513 Pfam PF00474 Sodium:solute symporter family 33 434 6.2E-123 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UP12_17875 61ca32d527d1dc51b0f4432185d5208a 513 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 148 173 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site UP12_17875 61ca32d527d1dc51b0f4432185d5208a 513 Gene3D G3DSA:1.20.1730.10 4 505 5.0E-65 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily UP12_17875 61ca32d527d1dc51b0f4432185d5208a 513 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 434 6.1E-92 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UP12_17875 61ca32d527d1dc51b0f4432185d5208a 513 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 416 436 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site UP12_04240 aaa7b478dd926b633da2a88831d92e83 175 Pfam PF12867 DinB superfamily 28 165 8.1E-16 T 11-10-2018 IPR024775 DinB-like domain UP12_04240 aaa7b478dd926b633da2a88831d92e83 175 Gene3D G3DSA:1.20.120.450 1 175 5.6E-48 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UP12_04240 aaa7b478dd926b633da2a88831d92e83 175 SUPERFAMILY SSF109854 5 172 7.63E-43 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UP12_04240 aaa7b478dd926b633da2a88831d92e83 175 Hamap MF_01256 Putative metal-dependent hydrolase . 2 175 36.292 T 11-10-2018 IPR023774 Putative metal-dependent hydrolase YfiT UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 6.7E-24 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.7E-24 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 6.7E-24 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.7E-24 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.7E-24 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 Gene3D G3DSA:3.40.50.720 6 265 1.3E-63 T 11-10-2018 UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 SUPERFAMILY SSF51735 7 261 9.09E-59 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17630 4ae450c214223bb946a72c1530a4a2bc 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 260 2.7E-38 T 11-10-2018 UP12_15640 9f77aa9bf0093578fe6175f18487732e 312 Pfam PF01497 Periplasmic binding protein 56 286 1.1E-36 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain UP12_15640 9f77aa9bf0093578fe6175f18487732e 312 Gene3D G3DSA:3.40.50.1980 154 312 2.8E-55 T 11-10-2018 UP12_15640 9f77aa9bf0093578fe6175f18487732e 312 SUPERFAMILY SSF53807 35 301 1.69E-55 T 11-10-2018 UP12_15640 9f77aa9bf0093578fe6175f18487732e 312 Gene3D G3DSA:3.40.50.1980 25 153 3.5E-27 T 11-10-2018 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.3E-26 T 11-10-2018 IPR000362 Fumarate lyase family UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.3E-26 T 11-10-2018 IPR000362 Fumarate lyase family UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.3E-26 T 11-10-2018 IPR000362 Fumarate lyase family UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.3E-26 T 11-10-2018 IPR000362 Fumarate lyase family UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 1.9E-24 T 11-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 SUPERFAMILY SSF48557 3 427 1.88E-139 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 1.0E-184 T 11-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 Pfam PF00206 Lyase 6 286 1.3E-80 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 SMART SM00998 349 429 9.9E-40 T 11-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 Gene3D G3DSA:1.10.275.10 1 92 5.2E-39 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 Gene3D G3DSA:1.20.200.10 93 348 1.6E-102 T 11-10-2018 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 2.9E-10 T 11-10-2018 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 2.9E-10 T 11-10-2018 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 2.9E-10 T 11-10-2018 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 2.9E-10 T 11-10-2018 UP12_03345 1bb0f9297f545cf470ceee8d2210fe1d 431 Gene3D G3DSA:1.10.40.30 349 431 3.4E-34 T 11-10-2018 UP12_07425 ebc3fe6a6cfc0462e5666747b73d7188 309 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 2 300 8.9E-87 T 11-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 UP12_07425 ebc3fe6a6cfc0462e5666747b73d7188 309 Pfam PF03419 Sporulation factor SpoIIGA 2 299 1.2E-83 T 11-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 UP12_07425 ebc3fe6a6cfc0462e5666747b73d7188 309 PIRSF PIRSF018571 1 302 8.1E-91 T 11-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 UP12_08585 d6f93b7e4d9ea8e60af302a26ee6191d 282 SMART SM00559 52 181 4.1E-44 T 11-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 UP12_08585 d6f93b7e4d9ea8e60af302a26ee6191d 282 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 259 4.7E-92 T 11-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UP12_08585 d6f93b7e4d9ea8e60af302a26ee6191d 282 Gene3D G3DSA:2.40.290.10 2 177 8.5E-23 T 11-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily UP12_08585 d6f93b7e4d9ea8e60af302a26ee6191d 282 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 186 3.0E-43 T 11-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 UP12_08585 d6f93b7e4d9ea8e60af302a26ee6191d 282 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 257 32.33 T 11-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UP12_08585 d6f93b7e4d9ea8e60af302a26ee6191d 282 SUPERFAMILY SSF100939 2 260 1.57E-50 T 11-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily UP12_08585 d6f93b7e4d9ea8e60af302a26ee6191d 282 PIRSF PIRSF006493 1 282 6.7E-103 T 11-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type UP12_08635 bb562498f65a4eb14b2871b74ed33732 738 Pfam PF13671 AAA domain 4 141 7.1E-12 T 11-10-2018 UP12_08635 bb562498f65a4eb14b2871b74ed33732 738 SUPERFAMILY SSF52540 1 148 3.32E-11 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08635 bb562498f65a4eb14b2871b74ed33732 738 SUPERFAMILY SSF56300 140 374 4.66E-26 T 11-10-2018 UP12_08635 bb562498f65a4eb14b2871b74ed33732 738 Pfam PF00149 Calcineurin-like phosphoesterase 175 363 2.2E-15 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_08635 bb562498f65a4eb14b2871b74ed33732 738 Gene3D G3DSA:3.60.21.10 167 399 3.8E-28 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_08635 bb562498f65a4eb14b2871b74ed33732 738 Gene3D G3DSA:3.40.50.300 1 166 1.7E-27 T 11-10-2018 UP12_08635 bb562498f65a4eb14b2871b74ed33732 738 Pfam PF09511 RNA ligase 453 665 3.5E-43 T 11-10-2018 IPR019039 RNA ligase T4 Rnl1, N-terminal UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SMART SM00357 73 133 1.4E-11 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SMART SM00357 138 202 1.5E-9 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Hamap MF_01895 Ribonuclease R [rnr]. 25 708 61.883 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Pfam PF08206 Ribonuclease B OB domain 74 132 1.5E-21 T 11-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Pfam PF08206 Ribonuclease B OB domain 148 201 8.0E-9 T 11-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Pfam PF00773 RNB domain 248 576 3.4E-117 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SMART SM00316 626 708 6.8E-20 T 11-10-2018 IPR022967 RNA-binding domain, S1 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Gene3D G3DSA:2.40.50.140 629 736 6.6E-27 T 11-10-2018 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SUPERFAMILY SSF50249 208 625 5.14E-149 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SUPERFAMILY SSF50249 55 135 3.18E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SUPERFAMILY SSF50249 628 707 1.27E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SUPERFAMILY SSF50249 126 225 3.29E-21 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 TIGRFAM TIGR02063 RNase_R: ribonuclease R 7 708 2.4E-287 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Pfam PF00575 S1 RNA binding domain 625 707 3.6E-16 T 11-10-2018 IPR003029 S1 domain GO:0003676 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 58 708 3.2E-264 T 11-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 ProSitePatterns PS01175 Ribonuclease II family signature. 545 569 - T 11-10-2018 IPR022966 Ribonuclease II/R, conserved site UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 SMART SM00955 248 578 8.5E-185 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Gene3D G3DSA:2.40.50.140 135 203 9.1E-11 T 11-10-2018 UP12_15805 0dfc325ae5d9e86bd3d7103cbc3d81e2 780 Gene3D G3DSA:2.40.50.140 60 134 1.7E-19 T 11-10-2018 UP12_14180 3f42cec999bc99bcbe7e7b702693767e 142 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 23 138 2.0E-40 T 11-10-2018 IPR020288 Protein of unknown function DUF2634 UP12_14180 3f42cec999bc99bcbe7e7b702693767e 142 SUPERFAMILY SSF160719 39 125 7.59E-5 T 11-10-2018 UP12_14180 3f42cec999bc99bcbe7e7b702693767e 142 Pfam PF10934 Protein of unknown function (DUF2634) 26 125 4.6E-26 T 11-10-2018 IPR020288 Protein of unknown function DUF2634 UP12_02545 abdf3bb77177cf436c2fef9f3fa10b35 116 SUPERFAMILY SSF50118 2 113 4.91E-41 T 11-10-2018 UP12_02545 abdf3bb77177cf436c2fef9f3fa10b35 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 8.3E-33 T 11-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 UP12_02545 abdf3bb77177cf436c2fef9f3fa10b35 116 Gene3D G3DSA:2.30.30.110 1 116 1.1E-51 T 11-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor UP12_02545 abdf3bb77177cf436c2fef9f3fa10b35 116 PIRSF PIRSF033490 1 113 1.7E-39 T 11-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 125 2.0E-15 T 11-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Gene3D G3DSA:3.40.50.300 1 148 1.8E-38 T 11-10-2018 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Pfam PF16193 AAA C-terminal domain 172 251 1.8E-26 T 11-10-2018 IPR032423 AAA C-terminal domain UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Gene3D G3DSA:1.20.272.10 226 330 5.5E-43 T 11-10-2018 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Gene3D G3DSA:1.10.8.60 149 224 1.8E-19 T 11-10-2018 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 SUPERFAMILY SSF52540 2 218 4.7E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Gene3D G3DSA:1.10.3710.10 366 421 1.8E-16 T 11-10-2018 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Gene3D G3DSA:1.10.3710.10 331 365 2.1E-8 T 11-10-2018 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 SMART SM00382 37 149 5.8E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 SUPERFAMILY SSF48019 237 419 1.7E-73 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 UP12_12050 d77ae6d5ba30ad2ef94088a771e8f6fa 421 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 417 1.4E-67 T 11-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 251 1.1E-72 T 11-10-2018 UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.6E-48 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.6E-48 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.6E-48 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.6E-48 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.6E-48 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.6E-48 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 SUPERFAMILY SSF51735 5 252 2.62E-86 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 Gene3D G3DSA:3.40.50.720 1 253 5.5E-89 T 11-10-2018 UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_17615 bd7fcd5c85b86273f9f328934cd8863c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 Gene3D G3DSA:3.40.50.720 3 239 5.0E-45 T 11-10-2018 UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 Pfam PF00106 short chain dehydrogenase 5 192 1.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.6E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.6E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.6E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.6E-14 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 SUPERFAMILY SSF51735 5 226 3.36E-45 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 4.8E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 4.8E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 4.8E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_02905 038edd5f1c97f66fbbc4392827c5dbb1 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_12450 7192fb167a77b2e9cf5b999eb3997005 388 SUPERFAMILY SSF52266 295 387 1.83E-10 T 11-10-2018 UP12_12450 7192fb167a77b2e9cf5b999eb3997005 388 Gene3D G3DSA:3.40.50.1110 275 385 2.2E-6 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_12450 7192fb167a77b2e9cf5b999eb3997005 388 PIRSF PIRSF021438 1 388 2.0E-161 T 11-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes UP12_12450 7192fb167a77b2e9cf5b999eb3997005 388 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 6 385 1.7E-136 T 11-10-2018 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD, Firmicutes UP12_12450 7192fb167a77b2e9cf5b999eb3997005 388 Pfam PF04914 DltD protein 41 386 3.9E-118 T 11-10-2018 IPR006998 DltD UP12_11855 a89c52956600b89202b6c2a54c482555 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 376 2.1E-112 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 UP12_11855 a89c52956600b89202b6c2a54c482555 387 Gene3D G3DSA:1.20.1090.10 187 387 1.3E-60 T 11-10-2018 UP12_11855 a89c52956600b89202b6c2a54c482555 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 175 203 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 UP12_11855 a89c52956600b89202b6c2a54c482555 387 Gene3D G3DSA:3.40.50.1970 1 186 3.1E-56 T 11-10-2018 UP12_11855 a89c52956600b89202b6c2a54c482555 387 SUPERFAMILY SSF56796 2 385 3.14E-115 T 11-10-2018 UP12_03590 03c4f5dd5ab0bfe37d7e89b72693704d 281 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 50 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_03590 03c4f5dd5ab0bfe37d7e89b72693704d 281 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.1E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_03590 03c4f5dd5ab0bfe37d7e89b72693704d 281 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.1E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_03590 03c4f5dd5ab0bfe37d7e89b72693704d 281 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 3.7E-19 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_03590 03c4f5dd5ab0bfe37d7e89b72693704d 281 SUPERFAMILY SSF46689 3 69 1.37E-19 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_03590 03c4f5dd5ab0bfe37d7e89b72693704d 281 Gene3D G3DSA:1.10.357.10 1 187 1.1E-30 T 11-10-2018 UP12_03580 dc9587f9ab166f1dd0b9c1e589edd42f 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 1.8E-208 T 11-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_03580 dc9587f9ab166f1dd0b9c1e589edd42f 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 96.813 T 11-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_03580 dc9587f9ab166f1dd0b9c1e589edd42f 485 Gene3D G3DSA:3.90.1300.10 2 485 1.7E-202 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_03580 dc9587f9ab166f1dd0b9c1e589edd42f 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 11-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UP12_03580 dc9587f9ab166f1dd0b9c1e589edd42f 485 SUPERFAMILY SSF75304 1 483 1.01E-169 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_03580 dc9587f9ab166f1dd0b9c1e589edd42f 485 Pfam PF01425 Amidase 24 465 2.2E-162 T 11-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_18555 8f82c6703cafda49fb707fd74ea584ca 319 Pfam PF00005 ABC transporter 31 171 2.2E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18555 8f82c6703cafda49fb707fd74ea584ca 319 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18555 8f82c6703cafda49fb707fd74ea584ca 319 SUPERFAMILY SSF52540 12 230 5.43E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18555 8f82c6703cafda49fb707fd74ea584ca 319 SMART SM00382 39 221 1.6E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18555 8f82c6703cafda49fb707fd74ea584ca 319 Gene3D G3DSA:3.40.50.300 3 268 1.5E-63 T 11-10-2018 UP12_13405 03342b22b9ff7f7653987fefeb8ec372 213 Pfam PF00571 CBS domain 74 126 6.4E-9 T 11-10-2018 IPR000644 CBS domain UP12_13405 03342b22b9ff7f7653987fefeb8ec372 213 Pfam PF00571 CBS domain 4 56 8.4E-15 T 11-10-2018 IPR000644 CBS domain UP12_13405 03342b22b9ff7f7653987fefeb8ec372 213 Gene3D G3DSA:3.10.580.10 1 151 9.7E-41 T 11-10-2018 UP12_13405 03342b22b9ff7f7653987fefeb8ec372 213 SUPERFAMILY SSF54631 1 131 1.64E-32 T 11-10-2018 UP12_13405 03342b22b9ff7f7653987fefeb8ec372 213 SMART SM00116 10 58 1.8E-13 T 11-10-2018 IPR000644 CBS domain UP12_13405 03342b22b9ff7f7653987fefeb8ec372 213 SMART SM00116 81 128 2.8E-12 T 11-10-2018 IPR000644 CBS domain UP12_15000 e65c15b858fd3cea01fec7189e5b41eb 135 Gene3D G3DSA:3.30.1330.30 1 131 9.0E-45 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_15000 e65c15b858fd3cea01fec7189e5b41eb 135 PIRSF PIRSF034303 1 135 4.1E-39 T 11-10-2018 IPR012543 Protein of unknown function DUF1694 UP12_15000 e65c15b858fd3cea01fec7189e5b41eb 135 SUPERFAMILY SSF160515 4 128 3.79E-39 T 11-10-2018 UP12_15000 e65c15b858fd3cea01fec7189e5b41eb 135 Pfam PF07997 Protein of unknown function (DUF1694) 4 119 3.7E-38 T 11-10-2018 IPR012543 Protein of unknown function DUF1694 UP12_10875 1db7421cec3216448cc3f5ead2fcb92e 97 Pfam PF14150 YesK-like protein 12 87 1.6E-22 T 11-10-2018 IPR025434 YesK-like protein UP12_17530 30fe1845d114830ccbe51da7245528ad 130 SUPERFAMILY SSF160631 9 124 3.14E-18 T 11-10-2018 UP12_17530 30fe1845d114830ccbe51da7245528ad 130 SMART SM00860 15 125 3.6E-5 T 11-10-2018 IPR018958 Knr4/Smi1-like domain UP12_17530 30fe1845d114830ccbe51da7245528ad 130 Pfam PF14568 SMI1-KNR4 cell-wall 18 123 5.5E-14 T 11-10-2018 UP12_17530 30fe1845d114830ccbe51da7245528ad 130 Gene3D G3DSA:3.40.1580.10 6 128 7.7E-22 T 11-10-2018 IPR037883 Knr4/Smi1-like domain superfamily UP12_00315 c4618190163e5e5b43fe803a10993aac 456 Pfam PF00483 Nucleotidyl transferase 6 217 4.4E-26 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 UP12_00315 c4618190163e5e5b43fe803a10993aac 456 Gene3D G3DSA:2.160.10.10 253 439 3.7E-51 T 11-10-2018 UP12_00315 c4618190163e5e5b43fe803a10993aac 456 Gene3D G3DSA:3.90.550.10 1 252 9.2E-82 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_00315 c4618190163e5e5b43fe803a10993aac 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 3 452 41.503 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 UP12_00315 c4618190163e5e5b43fe803a10993aac 456 SUPERFAMILY SSF51161 254 443 1.93E-50 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_00315 c4618190163e5e5b43fe803a10993aac 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 321 352 3.9E-6 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_00315 c4618190163e5e5b43fe803a10993aac 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 428 1.5E-6 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_00315 c4618190163e5e5b43fe803a10993aac 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 299 5.5E-10 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_00315 c4618190163e5e5b43fe803a10993aac 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 454 6.2E-188 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 UP12_00315 c4618190163e5e5b43fe803a10993aac 456 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 403 431 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UP12_00315 c4618190163e5e5b43fe803a10993aac 456 SUPERFAMILY SSF53448 4 307 5.63E-66 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_14470 0aae92a152fa9a25a2acb3566c778433 65 SUPERFAMILY SSF46955 7 56 4.21E-7 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_14470 0aae92a152fa9a25a2acb3566c778433 65 Pfam PF12728 Helix-turn-helix domain 7 55 8.2E-13 T 11-10-2018 UP12_14470 0aae92a152fa9a25a2acb3566c778433 65 Gene3D G3DSA:1.10.1660.10 1 55 1.0E-6 T 11-10-2018 UP12_14470 0aae92a152fa9a25a2acb3566c778433 65 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 51 4.3E-12 T 11-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 UP12_14260 f7d90b828e1e3f3c7d01520efe432b3f 384 Pfam PF14550 Putative phage serine protease XkdF 40 153 6.6E-47 T 11-10-2018 IPR027924 Phage-like element PBSX protein, XkdF UP12_03600 a80654547cd21628dac117028813e6d9 317 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 301 5.0E-46 T 11-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain UP12_03600 a80654547cd21628dac117028813e6d9 317 SUPERFAMILY SSF53590 1 309 9.55E-81 T 11-10-2018 IPR036452 Ribonucleoside hydrolase-like UP12_03600 a80654547cd21628dac117028813e6d9 317 Gene3D G3DSA:3.90.245.10 2 313 4.5E-96 T 11-10-2018 IPR036452 Ribonucleoside hydrolase-like UP12_02190 1bbef7a10957518ceddc730d081230cc 204 Gene3D G3DSA:2.60.40.2230 22 169 2.4E-33 T 11-10-2018 IPR038507 YcnI-like superfamily UP12_02190 1bbef7a10957518ceddc730d081230cc 204 Pfam PF07987 Domain of unkown function (DUF1775) 25 143 1.0E-18 T 11-10-2018 IPR012533 YcnI-like UP12_03510 0599ad89b724ec744e7f827058acc803 285 Gene3D G3DSA:1.10.1040.10 189 285 2.9E-29 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_03510 0599ad89b724ec744e7f827058acc803 285 SUPERFAMILY SSF48179 186 284 2.04E-30 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_03510 0599ad89b724ec744e7f827058acc803 285 PIRSF PIRSF000105 1 285 1.7E-81 T 11-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 UP12_03510 0599ad89b724ec744e7f827058acc803 285 Gene3D G3DSA:3.40.50.720 3 188 8.1E-58 T 11-10-2018 UP12_03510 0599ad89b724ec744e7f827058acc803 285 SUPERFAMILY SSF51735 1 186 5.61E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_03510 0599ad89b724ec744e7f827058acc803 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 283 2.6E-31 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_03510 0599ad89b724ec744e7f827058acc803 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 184 1.3E-54 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 Gene3D G3DSA:3.40.50.300 12 276 4.4E-111 T 11-10-2018 UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 Gene3D G3DSA:3.40.50.300 283 637 8.6E-136 T 11-10-2018 UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 SUPERFAMILY SSF52540 4 646 2.92E-187 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 Pfam PF13361 UvrD-like helicase C-terminal domain 280 620 8.6E-76 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 Gene3D G3DSA:1.10.486.10 386 550 8.6E-136 T 11-10-2018 UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 738 0.0 T 11-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 Gene3D G3DSA:1.10.10.160 116 190 4.4E-111 T 11-10-2018 IPR013986 DExx box DNA helicase domain superfamily UP12_03470 aae5a756bfb849fea6ae3c3a96fed2bf 740 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 275 8.0E-84 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 UP12_02185 f8edb0b200cd79f45a37f82b59eac3df 198 SUPERFAMILY SSF52218 1 195 4.02E-43 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_02185 f8edb0b200cd79f45a37f82b59eac3df 198 Pfam PF02525 Flavodoxin-like fold 1 185 8.0E-41 T 11-10-2018 IPR003680 Flavodoxin-like fold UP12_02185 f8edb0b200cd79f45a37f82b59eac3df 198 Gene3D G3DSA:3.40.50.360 1 196 2.4E-43 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_17220 fd931f86cbded0446c1c657dcf70002c 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 1.9E-92 T 11-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UP12_17220 fd931f86cbded0446c1c657dcf70002c 209 SUPERFAMILY SSF53271 4 207 3.41E-73 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like UP12_17220 fd931f86cbded0446c1c657dcf70002c 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 5.2E-75 T 11-10-2018 UP12_17220 fd931f86cbded0446c1c657dcf70002c 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.097 T 11-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 UP12_17220 fd931f86cbded0446c1c657dcf70002c 209 Gene3D G3DSA:3.40.50.2020 1 209 3.5E-83 T 11-10-2018 UP12_06440 8721c18b0504d100a536cdf0343dff2f 172 Gene3D G3DSA:3.10.450.40 34 102 4.8E-17 T 11-10-2018 UP12_06440 8721c18b0504d100a536cdf0343dff2f 172 Gene3D G3DSA:3.10.450.40 103 172 3.3E-20 T 11-10-2018 UP12_06440 8721c18b0504d100a536cdf0343dff2f 172 Pfam PF03413 Peptidase propeptide and YPEB domain 44 99 3.7E-11 T 11-10-2018 IPR025711 PepSY domain UP12_06440 8721c18b0504d100a536cdf0343dff2f 172 Pfam PF03413 Peptidase propeptide and YPEB domain 110 169 7.1E-17 T 11-10-2018 IPR025711 PepSY domain UP12_05760 b8b25865af362504a434f4620f0e39d9 303 Gene3D G3DSA:3.40.30.10 20 219 7.2E-25 T 11-10-2018 UP12_05760 b8b25865af362504a434f4620f0e39d9 303 Pfam PF13743 Thioredoxin 24 212 6.0E-69 T 11-10-2018 UP12_05760 b8b25865af362504a434f4620f0e39d9 303 SUPERFAMILY SSF52833 19 221 2.75E-27 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_01645 00c71fb4ea4ef5b71b65ffab598ff033 259 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 32 239 6.3E-77 T 11-10-2018 IPR022493 Integral membrane YkoY UP12_01645 00c71fb4ea4ef5b71b65ffab598ff033 259 Pfam PF03741 Integral membrane protein TerC family 35 212 1.1E-50 T 11-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 UP12_09070 1a0125c56341b492292632f02c73cefa 471 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 127 462 5.2E-109 T 11-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 UP12_09070 1a0125c56341b492292632f02c73cefa 471 Gene3D G3DSA:3.40.50.2300 1 105 8.1E-40 T 11-10-2018 UP12_09070 1a0125c56341b492292632f02c73cefa 471 SUPERFAMILY SSF52794 5 106 1.6E-36 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_09070 1a0125c56341b492292632f02c73cefa 471 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 8 96 2.0E-15 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_09070 1a0125c56341b492292632f02c73cefa 471 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 7 89 1.1E-30 T 11-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 UP12_17920 816a8db947dd86fabd3195cd481807f0 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 1.9E-14 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_17920 816a8db947dd86fabd3195cd481807f0 127 Gene3D G3DSA:3.10.180.10 1 127 2.1E-27 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_17920 816a8db947dd86fabd3195cd481807f0 127 SUPERFAMILY SSF54593 3 126 4.72E-26 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 SUPERFAMILY SSF48008 80 214 3.4E-25 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 Gene3D G3DSA:1.10.10.10 11 74 5.9E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 Pfam PF07729 FCD domain 84 208 1.0E-23 T 11-10-2018 IPR011711 GntR, C-terminal UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 SMART SM00895 84 209 9.5E-18 T 11-10-2018 IPR011711 GntR, C-terminal UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 SMART SM00345 16 74 7.9E-16 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 74 6.4E-18 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.2E-5 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.2E-5 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 SUPERFAMILY SSF46785 6 78 1.44E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02335 77e40069f1f59fe6a594d12e9a5dd900 224 Gene3D G3DSA:1.20.120.530 78 223 5.5E-27 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal UP12_01065 85d5c6118245f32fafdf3c5bdfa21887 273 Gene3D G3DSA:3.40.1700.10 101 254 9.3E-64 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily UP12_01065 85d5c6118245f32fafdf3c5bdfa21887 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 4 256 6.3E-111 T 11-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 UP12_01065 85d5c6118245f32fafdf3c5bdfa21887 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 118 235 8.2E-44 T 11-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal UP12_01065 85d5c6118245f32fafdf3c5bdfa21887 273 PIRSF PIRSF004793 4 268 9.9E-98 T 11-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 UP12_01065 85d5c6118245f32fafdf3c5bdfa21887 273 SUPERFAMILY SSF143597 40 240 3.01E-72 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily UP12_01065 85d5c6118245f32fafdf3c5bdfa21887 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 8 254 34.553 T 11-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 UP12_19180 934977d15278ec45966a5c88e3dbc7b3 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 11-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 UP12_19180 934977d15278ec45966a5c88e3dbc7b3 119 Pfam PF00825 Ribonuclease P 1 107 3.0E-35 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UP12_19180 934977d15278ec45966a5c88e3dbc7b3 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 101 1.0E-38 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UP12_19180 934977d15278ec45966a5c88e3dbc7b3 119 SUPERFAMILY SSF54211 1 113 9.86E-35 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_19180 934977d15278ec45966a5c88e3dbc7b3 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 20.696 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UP12_19180 934977d15278ec45966a5c88e3dbc7b3 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 111 7.1E-38 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 UP12_19180 934977d15278ec45966a5c88e3dbc7b3 119 Gene3D G3DSA:3.30.230.10 1 117 1.6E-41 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_09915 90068303921fe3f1e2e07e0eb9d94187 439 Pfam PF00860 Permease family 8 386 2.4E-119 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 UP12_09915 90068303921fe3f1e2e07e0eb9d94187 439 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 6 416 9.5E-143 T 11-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 UP12_09915 90068303921fe3f1e2e07e0eb9d94187 439 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 333 353 - T 11-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 UP12_09915 90068303921fe3f1e2e07e0eb9d94187 439 TIGRFAM TIGR03173 pbuX: xanthine permease 12 417 8.4E-164 T 11-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 UP12_17700 6f8f6a59923795eb34b4da45b29d21d3 205 Pfam PF00190 Cupin 28 132 3.6E-12 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_17700 6f8f6a59923795eb34b4da45b29d21d3 205 Gene3D G3DSA:2.60.120.10 2 172 5.2E-27 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_17700 6f8f6a59923795eb34b4da45b29d21d3 205 SUPERFAMILY SSF51182 28 170 7.54E-25 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_17700 6f8f6a59923795eb34b4da45b29d21d3 205 SMART SM00835 32 158 1.2E-16 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_09555 25643a4e992d7918f629a55c3e7b050b 208 Pfam PF10372 Bacterial membrane-spanning protein N-terminus 3 70 7.3E-26 T 11-10-2018 IPR019457 Uncharacterised domain YojJ, N-terminal UP12_09555 25643a4e992d7918f629a55c3e7b050b 208 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 80 195 1.3E-39 T 11-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal UP12_09555 25643a4e992d7918f629a55c3e7b050b 208 Gene3D G3DSA:1.10.287.770 5 66 3.4E-11 T 11-10-2018 UP12_09555 25643a4e992d7918f629a55c3e7b050b 208 Gene3D G3DSA:3.40.1700.10 67 208 6.5E-48 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily UP12_09555 25643a4e992d7918f629a55c3e7b050b 208 SUPERFAMILY SSF143597 39 198 1.83E-46 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily UP12_09555 25643a4e992d7918f629a55c3e7b050b 208 Hamap MF_00838 Diadenylate cyclase [dacB]. 15 201 33.844 T 11-10-2018 IPR034693 Diadenylate cyclase CdaS GO:0004016|GO:0006171 UP12_05865 1055e8efb90f01f47b90b3488cb65a48 162 Pfam PF07552 Spore Coat Protein X and V domain 104 161 4.1E-20 T 11-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 UP12_05865 1055e8efb90f01f47b90b3488cb65a48 162 Pfam PF07552 Spore Coat Protein X and V domain 40 97 1.3E-19 T 11-10-2018 IPR011428 Spore coat protein X/V GO:0030435|GO:0031160 UP12_05195 b5350381f462d66fd264087bb3e597e7 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 501 1.9E-21 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_05195 b5350381f462d66fd264087bb3e597e7 517 Gene3D G3DSA:3.30.300.310 413 516 4.0E-33 T 11-10-2018 UP12_05195 b5350381f462d66fd264087bb3e597e7 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_05195 b5350381f462d66fd264087bb3e597e7 517 Gene3D G3DSA:3.40.50.12780 1 410 1.5E-125 T 11-10-2018 UP12_05195 b5350381f462d66fd264087bb3e597e7 517 Pfam PF00501 AMP-binding enzyme 8 417 1.1E-114 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_05195 b5350381f462d66fd264087bb3e597e7 517 SUPERFAMILY SSF56801 6 513 1.15E-160 T 11-10-2018 UP12_11250 20d804735a4db249cb549ac66392e2f4 317 ProSitePatterns PS01125 ROK family signature. 137 164 - T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_11250 20d804735a4db249cb549ac66392e2f4 317 SUPERFAMILY SSF53067 5 313 2.69E-71 T 11-10-2018 UP12_11250 20d804735a4db249cb549ac66392e2f4 317 Gene3D G3DSA:3.30.420.40 7 309 1.3E-105 T 11-10-2018 UP12_11250 20d804735a4db249cb549ac66392e2f4 317 Pfam PF00480 ROK family 7 313 2.4E-77 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_11250 20d804735a4db249cb549ac66392e2f4 317 Gene3D G3DSA:3.30.420.40 128 297 1.3E-105 T 11-10-2018 UP12_11250 20d804735a4db249cb549ac66392e2f4 317 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 7 316 9.7E-128 T 11-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 UP12_04905 a78d250a4008a86d5d4f93a62c44ee0e 121 TIGRFAM TIGR00494 crcB: protein CrcB 6 110 3.8E-25 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UP12_04905 a78d250a4008a86d5d4f93a62c44ee0e 121 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 112 2.8E-20 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UP12_04905 a78d250a4008a86d5d4f93a62c44ee0e 121 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 15.942 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 185 8.1E-68 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 Gene3D G3DSA:1.20.5.100 199 230 2.1E-19 T 11-10-2018 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 PIRSF PIRSF000124 3 432 1.8E-142 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 SMART SM00984 315 417 5.7E-42 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 200 292 1.8E-39 T 11-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 PIRSF PIRSF500134 3 435 7.3E-177 T 11-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 Gene3D G3DSA:3.40.50.720 231 444 2.8E-74 T 11-10-2018 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 316 417 6.8E-29 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 SUPERFAMILY SSF52413 302 427 3.01E-34 T 11-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 SUPERFAMILY SSF51735 3 195 3.76E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 Gene3D G3DSA:3.40.50.720 1 198 8.6E-75 T 11-10-2018 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 SUPERFAMILY SSF48179 200 297 1.24E-33 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_16650 cab59b513b5205235af4ee17c4ebbbe0 445 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 413 4.8E-139 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 UP12_05965 4997a0212db26aed47448e65246e1c8a 131 Gene3D G3DSA:3.10.450.50 22 131 6.2E-13 T 11-10-2018 UP12_09325 e67217c614c1aa38ad9cdfeb5242bd3c 186 Gene3D G3DSA:3.40.630.30 6 179 2.7E-47 T 11-10-2018 UP12_09325 e67217c614c1aa38ad9cdfeb5242bd3c 186 SUPERFAMILY SSF55729 8 176 4.01E-43 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_09325 e67217c614c1aa38ad9cdfeb5242bd3c 186 Pfam PF13302 Acetyltransferase (GNAT) domain 8 152 1.2E-18 T 11-10-2018 IPR000182 GNAT domain UP12_04840 128c4c18a5a90305f3a04fad6f9675f4 143 Pfam PF02082 Transcriptional regulator 1 81 5.5E-25 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_04840 128c4c18a5a90305f3a04fad6f9675f4 143 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 132 1.7E-38 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type UP12_04840 128c4c18a5a90305f3a04fad6f9675f4 143 Gene3D G3DSA:1.10.10.10 1 141 1.7E-38 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04840 128c4c18a5a90305f3a04fad6f9675f4 143 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 11-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site UP12_04840 128c4c18a5a90305f3a04fad6f9675f4 143 SUPERFAMILY SSF46785 2 135 7.86E-38 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_12770 c47306b7a69f24ea7fabcec21920001c 67 Gene3D G3DSA:1.10.260.40 3 67 4.7E-16 T 11-10-2018 UP12_12770 c47306b7a69f24ea7fabcec21920001c 67 Pfam PF12844 Helix-turn-helix domain 10 67 4.2E-10 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_12770 c47306b7a69f24ea7fabcec21920001c 67 SMART SM00530 11 66 1.1E-6 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_12770 c47306b7a69f24ea7fabcec21920001c 67 SUPERFAMILY SSF47413 5 67 8.16E-15 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_15345 ca98306e288a309b949a9324d3ee2d0e 216 Gene3D G3DSA:3.40.50.360 1 212 6.5E-45 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_15345 ca98306e288a309b949a9324d3ee2d0e 216 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 210 22.472 T 11-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 UP12_15345 ca98306e288a309b949a9324d3ee2d0e 216 Pfam PF02525 Flavodoxin-like fold 1 205 7.3E-34 T 11-10-2018 IPR003680 Flavodoxin-like fold UP12_15345 ca98306e288a309b949a9324d3ee2d0e 216 SUPERFAMILY SSF52218 1 210 9.7E-37 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 SMART SM00843 718 783 2.8E-40 T 11-10-2018 IPR018541 FtsK gamma domain UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 SUPERFAMILY SSF46785 720 785 9.11E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 Pfam PF01580 FtsK/SpoIIIE family 426 622 2.6E-64 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 SMART SM00382 461 643 4.3E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 Pfam PF09397 Ftsk gamma domain 721 780 1.1E-29 T 11-10-2018 IPR018541 FtsK gamma domain UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 Gene3D G3DSA:3.30.980.40 318 421 7.3E-39 T 11-10-2018 UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 SUPERFAMILY SSF52540 399 694 2.12E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 Gene3D G3DSA:1.10.10.10 715 779 3.6E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08225 f8df4b08b1bd7ac030d2738091806963 790 Gene3D G3DSA:3.40.50.300 423 708 3.6E-111 T 11-10-2018 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 PIRSF PIRSF000850 230 297 3.6E-4 T 11-10-2018 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 PIRSF PIRSF000850 291 387 0.05 T 11-10-2018 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 PIRSF PIRSF000850 35 104 0.27 T 11-10-2018 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 Pfam PF13091 PLD-like domain 240 364 2.3E-28 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 Pfam PF13091 PLD-like domain 58 171 1.2E-11 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 SMART SM00155 140 167 2.2E-4 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 SMART SM00155 311 338 4.8E-4 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 Gene3D G3DSA:3.30.870.10 38 221 2.8E-39 T 11-10-2018 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 36 396 2.0E-95 T 11-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 Gene3D G3DSA:3.30.870.10 225 369 3.9E-24 T 11-10-2018 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 SUPERFAMILY SSF56024 231 383 1.01E-35 T 11-10-2018 UP12_17405 f506ebccbf4ddb528e411ecb6e4cab65 398 SUPERFAMILY SSF56024 41 219 2.1E-45 T 11-10-2018 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 SUPERFAMILY SSF46894 123 198 2.38E-18 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 Pfam PF00072 Response regulator receiver domain 4 113 1.8E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 1.3E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 1.3E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 1.3E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 SMART SM00448 2 113 3.4E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 190 2.2E-18 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 SUPERFAMILY SSF52172 1 129 6.12E-28 T 11-10-2018 IPR011006 CheY-like superfamily UP12_13250 5844763f041aa5cab34f55848e2fc312 199 Gene3D G3DSA:3.40.50.12740 2 197 3.1E-57 T 11-10-2018 UP12_13250 5844763f041aa5cab34f55848e2fc312 199 SMART SM00421 135 192 6.0E-19 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_16200 87db806d8be1141a61eb56bc16257e40 250 Gene3D G3DSA:3.30.2140.20 1 246 1.4E-65 T 11-10-2018 UP12_16200 87db806d8be1141a61eb56bc16257e40 250 Pfam PF00797 N-acetyltransferase 19 231 2.6E-43 T 11-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 UP12_16200 87db806d8be1141a61eb56bc16257e40 250 PRINTS PR01543 Arylamine N-acetyltransferase signature 18 41 1.8E-8 T 11-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 UP12_16200 87db806d8be1141a61eb56bc16257e40 250 PRINTS PR01543 Arylamine N-acetyltransferase signature 66 88 1.8E-8 T 11-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 UP12_16200 87db806d8be1141a61eb56bc16257e40 250 PRINTS PR01543 Arylamine N-acetyltransferase signature 99 124 1.8E-8 T 11-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 UP12_16200 87db806d8be1141a61eb56bc16257e40 250 PRINTS PR01543 Arylamine N-acetyltransferase signature 42 65 1.8E-8 T 11-10-2018 IPR001447 Arylamine N-acetyltransferase GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 UP12_16200 87db806d8be1141a61eb56bc16257e40 250 SUPERFAMILY SSF54001 2 243 1.77E-55 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_17635 36cd0a77a1030bd0b49be34b66d806f0 151 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 2 147 1.0E-25 T 11-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UP12_17635 36cd0a77a1030bd0b49be34b66d806f0 151 SUPERFAMILY SSF51182 1 149 3.94E-43 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_17635 36cd0a77a1030bd0b49be34b66d806f0 151 Gene3D G3DSA:2.60.120.10 1 150 2.3E-55 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_17635 36cd0a77a1030bd0b49be34b66d806f0 151 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 2 147 7.5E-26 T 11-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 UP12_16350 1d69baa9b6874792e14633046c1126dc 128 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 3 114 4.2E-28 T 11-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV UP12_17870 c7aab65fce41071bbe193bc734886487 104 Pfam PF04341 Protein of unknown function, DUF485 13 95 1.9E-24 T 11-10-2018 IPR007436 Protein of unknown function DUF485 UP12_03295 fbd20c5623be95d2fa61e000e62fc662 889 Pfam PF13087 AAA domain 593 702 1.3E-14 T 11-10-2018 UP12_03295 fbd20c5623be95d2fa61e000e62fc662 889 Gene3D G3DSA:3.40.960.10 789 885 1.4E-5 T 11-10-2018 UP12_03295 fbd20c5623be95d2fa61e000e62fc662 889 Gene3D G3DSA:3.40.50.300 560 733 1.7E-29 T 11-10-2018 UP12_03295 fbd20c5623be95d2fa61e000e62fc662 889 Pfam PF10881 Protein of unknown function (DUF2726) 790 879 3.9E-10 T 11-10-2018 IPR024402 Domain of unknown function DUF2726 UP12_03295 fbd20c5623be95d2fa61e000e62fc662 889 Pfam PF13086 AAA domain 175 517 3.6E-17 T 11-10-2018 UP12_03295 fbd20c5623be95d2fa61e000e62fc662 889 SUPERFAMILY SSF52540 172 714 1.18E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 SMART SM00434 10 463 7.1E-257 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Gene3D G3DSA:3.30.1360.40 235 331 4.5E-195 T 11-10-2018 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 606 650 5.3E-7 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 654 698 9.1E-13 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 507 521 2.8 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 598 1.2E-5 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 753 2.8E-7 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 SUPERFAMILY SSF101904 499 808 1.03E-97 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 800 1.3E-269 T 11-10-2018 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 7 745 0.0 T 11-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 31 467 2.0E-149 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Gene3D G3DSA:3.90.199.10 31 485 4.5E-195 T 11-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 SUPERFAMILY SSF56719 30 485 4.97E-167 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 6 803 33.159 T 11-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Gene3D G3DSA:2.120.10.90 499 811 5.3E-108 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal UP12_08805 9a9e2241bbcf6eb75cb9b5c18cf89d35 812 Gene3D G3DSA:1.10.268.10 368 456 4.5E-195 T 11-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 UP12_06895 da71490883aa3f6e0326b5b4b6b613fb 152 SUPERFAMILY SSF52833 2 141 3.52E-33 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_06895 da71490883aa3f6e0326b5b4b6b613fb 152 Pfam PF00578 AhpC/TSA family 5 125 3.9E-14 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_06895 da71490883aa3f6e0326b5b4b6b613fb 152 Gene3D G3DSA:3.40.30.10 1 148 3.4E-40 T 11-10-2018 UP12_09820 76163f82c6bbad56a31a1b9e4bfe322b 213 Gene3D G3DSA:1.20.58.1910 100 205 6.8E-36 T 11-10-2018 UP12_09820 76163f82c6bbad56a31a1b9e4bfe322b 213 SUPERFAMILY SSF109604 2 199 3.14E-56 T 11-10-2018 UP12_09820 76163f82c6bbad56a31a1b9e4bfe322b 213 SMART SM00471 21 136 1.1E-6 T 11-10-2018 IPR003607 HD/PDEase domain UP12_09820 76163f82c6bbad56a31a1b9e4bfe322b 213 Gene3D G3DSA:1.10.472.50 1 99 3.5E-28 T 11-10-2018 UP12_09820 76163f82c6bbad56a31a1b9e4bfe322b 213 Pfam PF01966 HD domain 28 126 1.4E-6 T 11-10-2018 IPR006674 HD domain UP12_12760 54afee61c60229451de371d24ec957d5 273 Pfam PF01695 IstB-like ATP binding protein 79 243 2.0E-7 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 UP12_12760 54afee61c60229451de371d24ec957d5 273 SUPERFAMILY SSF52540 78 251 1.06E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12760 54afee61c60229451de371d24ec957d5 273 Gene3D G3DSA:3.40.50.300 60 258 5.1E-32 T 11-10-2018 UP12_18250 ba77baeffe85369e55a2810a2ecdf225 225 Gene3D G3DSA:3.90.640.20 146 225 8.4E-14 T 11-10-2018 IPR037126 PdaC/RsiV-like superfamily UP12_18250 ba77baeffe85369e55a2810a2ecdf225 225 Gene3D G3DSA:3.30.565.40 27 141 4.7E-10 T 11-10-2018 UP12_18250 ba77baeffe85369e55a2810a2ecdf225 225 Pfam PF13739 Domain of unknown function (DUF4163) 39 127 2.2E-10 T 11-10-2018 IPR025303 Deacetylase PdaC UP12_18250 ba77baeffe85369e55a2810a2ecdf225 225 Pfam PF11738 Protein of unknown function (DUF3298) 154 221 8.7E-11 T 11-10-2018 IPR021729 Domain of unknown function DUF3298 UP12_08620 257e5837318a13de84890a876dd90e26 240 Hamap MF_02104 Lactate utilization protein C [lutC]. 4 237 44.602 T 11-10-2018 IPR022823 Lactate utilization protein C UP12_08620 257e5837318a13de84890a876dd90e26 240 SUPERFAMILY SSF100950 46 238 1.13E-39 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_08620 257e5837318a13de84890a876dd90e26 240 Pfam PF02589 LUD domain 53 237 1.8E-35 T 11-10-2018 IPR003741 LUD domain UP12_08620 257e5837318a13de84890a876dd90e26 240 Gene3D G3DSA:3.40.50.10420 46 237 6.3E-36 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 SUPERFAMILY SSF54631 97 223 5.12E-22 T 11-10-2018 UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 Gene3D G3DSA:3.10.580.10 84 232 1.1E-61 T 11-10-2018 UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 Pfam PF08279 HTH domain 29 81 8.0E-13 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 SMART SM00116 106 154 0.086 T 11-10-2018 IPR000644 CBS domain UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 SMART SM00116 173 224 0.053 T 11-10-2018 IPR000644 CBS domain UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 SUPERFAMILY SSF46785 25 100 8.49E-14 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 Gene3D G3DSA:1.10.10.10 10 83 6.3E-9 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 Pfam PF00571 CBS domain 167 223 7.6E-5 T 11-10-2018 IPR000644 CBS domain UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 Pfam PF00571 CBS domain 100 153 4.2E-6 T 11-10-2018 IPR000644 CBS domain UP12_11450 92797bbcb13a7bb0bcc8cca9a9241d72 232 PIRSF PIRSF026546 24 230 3.5E-102 T 11-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS UP12_05995 90bbebe564960bc9558b8b2d2c8a7f18 372 Pfam PF13181 Tetratricopeptide repeat 337 361 4.3E-5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_05995 90bbebe564960bc9558b8b2d2c8a7f18 372 Gene3D G3DSA:1.25.40.10 1 372 1.3E-124 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_05995 90bbebe564960bc9558b8b2d2c8a7f18 372 SUPERFAMILY SSF48452 114 365 9.36E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_05995 90bbebe564960bc9558b8b2d2c8a7f18 372 Pfam PF13424 Tetratricopeptide repeat 192 246 6.2E-10 T 11-10-2018 UP12_05995 90bbebe564960bc9558b8b2d2c8a7f18 372 SMART SM00028 217 250 1.2E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_05995 90bbebe564960bc9558b8b2d2c8a7f18 372 SMART SM00028 136 169 61.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_05995 90bbebe564960bc9558b8b2d2c8a7f18 372 SMART SM00028 330 363 0.55 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_17145 c8014c33b1d11d9c691b1a69bd1bf5d5 231 SMART SM00327 36 223 8.7E-20 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_17145 c8014c33b1d11d9c691b1a69bd1bf5d5 231 SUPERFAMILY SSF53300 28 222 2.08E-26 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_17145 c8014c33b1d11d9c691b1a69bd1bf5d5 231 Pfam PF00092 von Willebrand factor type A domain 39 221 3.4E-17 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_17145 c8014c33b1d11d9c691b1a69bd1bf5d5 231 Gene3D G3DSA:3.40.50.410 37 226 2.2E-28 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 Gene3D G3DSA:1.20.1260.110 146 291 2.0E-45 T 11-10-2018 IPR038331 DisA, linker domain superfamily UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 Pfam PF10635 DisA bacterial checkpoint controller linker region 145 283 6.2E-50 T 11-10-2018 IPR018906 DNA integrity scanning, DisA, linker region UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 Hamap MF_01438 DNA integrity scanning protein DisA [disA]. 1 356 44.843 T 11-10-2018 IPR023763 DNA integrity scanning protein, DisA UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 Gene3D G3DSA:3.40.1700.10 10 145 1.7E-56 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 28 140 3.4E-28 T 11-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 SUPERFAMILY SSF47781 241 356 1.81E-13 T 11-10-2018 IPR010994 RuvA domain 2-like UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 SUPERFAMILY SSF143597 21 145 6.28E-31 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily UP12_00590 2bb26da8bec68e49dd787f469fe228fe 359 Gene3D G3DSA:1.10.150.20 292 355 4.2E-26 T 11-10-2018 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 SUPERFAMILY SSF46689 361 453 1.58E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 SMART SM00382 169 322 1.8E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 Gene3D G3DSA:3.30.450.20 4 118 4.3E-14 T 11-10-2018 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 173 186 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 Pfam PF02954 Bacterial regulatory protein, Fis family 414 453 1.1E-12 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 SUPERFAMILY SSF55785 9 113 4.19E-14 T 11-10-2018 IPR035965 PAS domain superfamily UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 Gene3D G3DSA:3.40.50.300 134 318 1.8E-53 T 11-10-2018 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 436 456 2.0E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 419 436 2.0E-6 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 Gene3D G3DSA:1.10.10.60 389 455 2.3E-15 T 11-10-2018 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 234 249 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 Pfam PF00989 PAS fold 11 118 2.6E-8 T 11-10-2018 IPR013767 PAS fold GO:0006355 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 361 370 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 Gene3D G3DSA:1.10.8.60 319 387 5.4E-25 T 11-10-2018 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 125 9.9E-12 T 11-10-2018 IPR000014 PAS domain UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 SMART SM00091 9 75 0.0037 T 11-10-2018 IPR000014 PAS domain UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 Pfam PF00158 Sigma-54 interaction domain 151 312 1.1E-57 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 UP12_09670 d2c433dc4149094f3001b523b7dc6efb 458 SUPERFAMILY SSF52540 152 382 3.25E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17480 dca0ba5a78729b441ba709e404f22df9 61 Gene3D G3DSA:3.30.429.10 2 60 1.0E-26 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily UP12_17480 dca0ba5a78729b441ba709e404f22df9 61 SUPERFAMILY SSF55331 2 60 6.15E-20 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily UP12_17480 dca0ba5a78729b441ba709e404f22df9 61 Pfam PF01361 Tautomerase enzyme 2 60 2.5E-23 T 11-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 UP12_17480 dca0ba5a78729b441ba709e404f22df9 61 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 61 2.3E-26 T 11-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 UP12_10745 cdb51f9a5929930bdf5f29719b53c444 435 Gene3D G3DSA:3.90.1150.10 23 419 6.9E-188 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_10745 cdb51f9a5929930bdf5f29719b53c444 435 Pfam PF12897 Alanine-glyoxylate amino-transferase 7 426 4.8E-186 T 11-10-2018 IPR024551 Aminotransferase, putative UP12_10745 cdb51f9a5929930bdf5f29719b53c444 435 SUPERFAMILY SSF53383 35 413 1.87E-50 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_10745 cdb51f9a5929930bdf5f29719b53c444 435 Gene3D G3DSA:3.40.640.10 63 307 6.9E-188 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_02600 26ceac0c8d4d94850d1efe9b9cd2afa9 325 Pfam PF00676 Dehydrogenase E1 component 16 311 2.5E-98 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UP12_02600 26ceac0c8d4d94850d1efe9b9cd2afa9 325 Gene3D G3DSA:3.40.50.970 1 325 1.0E-127 T 11-10-2018 UP12_02600 26ceac0c8d4d94850d1efe9b9cd2afa9 325 SUPERFAMILY SSF52518 5 323 8.94E-103 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_13345 4cbd7e262bdae854438abf48739c9156 271 Gene3D G3DSA:3.20.20.140 2 270 9.2E-67 T 11-10-2018 UP12_13345 4cbd7e262bdae854438abf48739c9156 271 Pfam PF13263 PHP-associated 237 265 5.2E-6 T 11-10-2018 UP12_13345 4cbd7e262bdae854438abf48739c9156 271 Pfam PF02811 PHP domain 5 165 7.8E-11 T 11-10-2018 IPR004013 PHP domain GO:0003824 UP12_13345 4cbd7e262bdae854438abf48739c9156 271 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 5 264 3.5E-78 T 11-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 UP12_13345 4cbd7e262bdae854438abf48739c9156 271 SUPERFAMILY SSF89550 4 262 3.66E-34 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 UP12_05370 53ba6eac8c435da5b684b330d460f6b3 53 Pfam PF09388 Spo0E like sporulation regulatory protein 2 40 3.8E-14 T 11-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 UP12_05370 53ba6eac8c435da5b684b330d460f6b3 53 SUPERFAMILY SSF140500 2 49 2.09E-14 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 UP12_05370 53ba6eac8c435da5b684b330d460f6b3 53 Gene3D G3DSA:1.20.58.990 1 52 3.8E-14 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 UP12_17890 2bb39626df949d3842174dfc454fe442 222 Gene3D G3DSA:3.20.20.70 1 220 4.9E-77 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_17890 2bb39626df949d3842174dfc454fe442 222 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 14 211 3.7E-68 T 11-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17890 2bb39626df949d3842174dfc454fe442 222 Pfam PF02581 Thiamine monophosphate synthase 15 198 1.5E-60 T 11-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17890 2bb39626df949d3842174dfc454fe442 222 SUPERFAMILY SSF51391 8 213 3.14E-68 T 11-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_17890 2bb39626df949d3842174dfc454fe442 222 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 13 216 28.465 T 11-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_01730 1651bafefd48aaf884824af292222319 441 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 84 432 1.6E-113 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UP12_01730 1651bafefd48aaf884824af292222319 441 Gene3D G3DSA:3.90.1150.10 314 441 2.0E-32 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_01730 1651bafefd48aaf884824af292222319 441 Gene3D G3DSA:3.40.640.10 1 311 4.9E-95 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_01730 1651bafefd48aaf884824af292222319 441 PIRSF PIRSF000390 44 440 1.3E-115 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase UP12_01730 1651bafefd48aaf884824af292222319 441 SUPERFAMILY SSF53383 84 437 1.75E-94 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_18960 0eb0557d3aa8585fee44ebb698721b1c 318 Pfam PF16226 Domain of unknown function (DUF4885) 5 316 4.0E-104 T 11-10-2018 IPR032617 Protein of unknown function DUF4885 UP12_06020 04c70651ad5da392a07323783b9ccf3f 298 Gene3D G3DSA:3.30.200.20 2 94 2.1E-7 T 11-10-2018 UP12_06020 04c70651ad5da392a07323783b9ccf3f 298 Gene3D G3DSA:3.90.1200.10 108 297 1.6E-19 T 11-10-2018 UP12_06020 04c70651ad5da392a07323783b9ccf3f 298 Pfam PF01636 Phosphotransferase enzyme family 23 261 2.9E-23 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase UP12_06020 04c70651ad5da392a07323783b9ccf3f 298 SUPERFAMILY SSF56112 12 258 6.38E-29 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_04675 6b24ad96b7842c5e37c2c56f69ac9c96 210 SUPERFAMILY SSF51230 40 111 1.7E-9 T 11-10-2018 IPR011053 Single hybrid motif UP12_04675 6b24ad96b7842c5e37c2c56f69ac9c96 210 Gene3D G3DSA:2.40.50.100 47 101 5.6E-6 T 11-10-2018 UP12_04675 6b24ad96b7842c5e37c2c56f69ac9c96 210 Gene3D G3DSA:2.40.30.170 102 210 7.5E-34 T 11-10-2018 UP12_04675 6b24ad96b7842c5e37c2c56f69ac9c96 210 Pfam PF13437 HlyD family secretion protein 85 201 3.6E-14 T 11-10-2018 UP12_01285 81eb29e705e26101e5e8f8e6138e8b98 160 Pfam PF13686 DsrE/DsrF/DrsH-like family 5 159 5.9E-65 T 11-10-2018 IPR032836 DsrE2-like family UP12_01285 81eb29e705e26101e5e8f8e6138e8b98 160 SUPERFAMILY SSF75169 6 152 1.51E-20 T 11-10-2018 IPR027396 DsrEFH-like UP12_01285 81eb29e705e26101e5e8f8e6138e8b98 160 Gene3D G3DSA:3.40.1260.10 2 160 6.6E-64 T 11-10-2018 IPR027396 DsrEFH-like UP12_11665 d44328f2be2d8042d6eef839ea9e1fc9 366 Pfam PF01926 50S ribosome-binding GTPase 162 226 1.3E-13 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_11665 d44328f2be2d8042d6eef839ea9e1fc9 366 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 366 1.7E-159 T 11-10-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH UP12_11665 d44328f2be2d8042d6eef839ea9e1fc9 366 SUPERFAMILY SSF52540 61 278 1.3E-32 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11665 d44328f2be2d8042d6eef839ea9e1fc9 366 Gene3D G3DSA:3.40.50.300 56 224 2.8E-51 T 11-10-2018 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 SUPERFAMILY SSF64518 1 306 1.16E-88 T 11-10-2018 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 Pfam PF00700 Bacterial flagellin C-terminal helical region 220 305 6.6E-33 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 146 1.5E-40 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 Gene3D G3DSA:1.20.1330.10 43 188 3.1E-58 T 11-10-2018 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 Gene3D G3DSA:1.20.58.1830 3 31 3.1E-58 T 11-10-2018 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 PRINTS PR00207 Flagellin signature 74 93 3.1E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 PRINTS PR00207 Flagellin signature 110 133 3.1E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 PRINTS PR00207 Flagellin signature 35 52 3.1E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06115 fcdf0e509fd36cbe64f2770518b340f4 306 Gene3D G3DSA:1.10.8.410 253 306 3.0E-29 T 11-10-2018 UP12_08405 fb831674ce1e479ff220adffbce08f90 149 SUPERFAMILY SSF82784 3 141 9.03E-30 T 11-10-2018 IPR036102 OsmC/Ohr superfamily UP12_08405 fb831674ce1e479ff220adffbce08f90 149 Gene3D G3DSA:3.30.300.20 6 145 3.3E-29 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_08405 fb831674ce1e479ff220adffbce08f90 149 TIGRFAM TIGR03563 perox_SACOL1771: peroxiredoxin, SACOL1771 subfamily 4 140 3.3E-66 T 11-10-2018 IPR019905 Peroxiredoxin OsmC-like protein, Firmicutes UP12_08405 fb831674ce1e479ff220adffbce08f90 149 Pfam PF02566 OsmC-like protein 39 142 2.3E-16 T 11-10-2018 IPR003718 OsmC/Ohr family UP12_09450 d4c185de6713d916e9945377b32639cc 305 SUPERFAMILY SSF51621 11 293 1.21E-92 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UP12_09450 d4c185de6713d916e9945377b32639cc 305 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 11 295 43.961 T 11-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 UP12_09450 d4c185de6713d916e9945377b32639cc 305 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 15 294 2.1E-121 T 11-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 UP12_09450 d4c185de6713d916e9945377b32639cc 305 Gene3D G3DSA:3.20.20.60 1 301 3.8E-105 T 11-10-2018 UP12_09450 d4c185de6713d916e9945377b32639cc 305 Pfam PF13714 Phosphoenolpyruvate phosphomutase 19 257 4.6E-50 T 11-10-2018 UP12_09450 d4c185de6713d916e9945377b32639cc 305 ProSitePatterns PS00161 Isocitrate lyase signature. 126 131 - T 11-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 UP12_08730 99c2ffe55f5f95dfc649e6a7aa3e61da 142 ProDom PD086666 YNEK BH2332 11 140 2.0E-44 T 11-10-2018 IPR020203 Uncharacterised protein family, YneK UP12_08730 99c2ffe55f5f95dfc649e6a7aa3e61da 142 Pfam PF11084 Protein of unknown function (DUF2621) 4 141 7.8E-74 T 11-10-2018 IPR020203 Uncharacterised protein family, YneK UP12_07320 7905b415ddbacf10d6943d56e37e6440 159 SUPERFAMILY SSF55729 25 141 6.65E-15 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_07320 7905b415ddbacf10d6943d56e37e6440 159 Pfam PF13508 Acetyltransferase (GNAT) domain 66 129 1.5E-7 T 11-10-2018 IPR000182 GNAT domain UP12_07320 7905b415ddbacf10d6943d56e37e6440 159 PIRSF PIRSF037732 1 159 5.9E-84 T 11-10-2018 IPR017274 Putative N-acetyltransferase YlbP UP12_07320 7905b415ddbacf10d6943d56e37e6440 159 Gene3D G3DSA:3.40.630.30 1 159 4.5E-61 T 11-10-2018 UP12_07320 7905b415ddbacf10d6943d56e37e6440 159 Hamap MF_00824 Uncharacterized N-acetyltransferase . 1 148 42.269 T 11-10-2018 IPR017274 Putative N-acetyltransferase YlbP UP12_14755 77041c7358855cd7b616a7c60c55922d 133 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 94 112 - T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 UP12_14755 77041c7358855cd7b616a7c60c55922d 133 Gene3D G3DSA:2.60.120.460 1 131 2.3E-54 T 11-10-2018 IPR035917 YjbQ-like superfamily UP12_14755 77041c7358855cd7b616a7c60c55922d 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 3 130 2.9E-52 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 UP12_14755 77041c7358855cd7b616a7c60c55922d 133 PIRSF PIRSF004681 1 132 1.2E-38 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 UP12_14755 77041c7358855cd7b616a7c60c55922d 133 SUPERFAMILY SSF111038 2 129 2.62E-47 T 11-10-2018 IPR035917 YjbQ-like superfamily UP12_14755 77041c7358855cd7b616a7c60c55922d 133 Pfam PF01894 Uncharacterised protein family UPF0047 16 129 1.3E-39 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 UP12_07500 0967a6cf9fa061d673a7fbd7ba28745e 258 Pfam PF01479 S4 domain 183 227 7.3E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_07500 0967a6cf9fa061d673a7fbd7ba28745e 258 Gene3D G3DSA:3.30.70.330 81 165 2.8E-25 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily UP12_07500 0967a6cf9fa061d673a7fbd7ba28745e 258 SMART SM00363 182 239 1.3E-11 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_07500 0967a6cf9fa061d673a7fbd7ba28745e 258 Gene3D G3DSA:3.30.1370.160 3 80 4.6E-31 T 11-10-2018 UP12_07500 0967a6cf9fa061d673a7fbd7ba28745e 258 SUPERFAMILY SSF55174 36 252 5.36E-29 T 11-10-2018 UP12_07500 0967a6cf9fa061d673a7fbd7ba28745e 258 Gene3D G3DSA:3.10.290.10 181 233 2.0E-8 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_04295 d627ef4fb28b86d60a3fccdb80ef9eff 263 Gene3D G3DSA:1.10.10.2800 1 107 1.1E-36 T 11-10-2018 UP12_04295 d627ef4fb28b86d60a3fccdb80ef9eff 263 Gene3D G3DSA:1.10.10.10 108 152 1.5E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04295 d627ef4fb28b86d60a3fccdb80ef9eff 263 Hamap MF_01114 Regulatory protein RecX [recX]. 42 209 17.499 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 UP12_04295 d627ef4fb28b86d60a3fccdb80ef9eff 263 Pfam PF02631 RecX family 84 204 2.0E-28 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 UP12_04295 d627ef4fb28b86d60a3fccdb80ef9eff 263 Pfam PF02631 RecX family 210 261 8.7E-5 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 UP12_04295 d627ef4fb28b86d60a3fccdb80ef9eff 263 Gene3D G3DSA:1.10.10.10 153 213 1.4E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04295 d627ef4fb28b86d60a3fccdb80ef9eff 263 Gene3D G3DSA:1.10.10.10 214 263 7.1E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16675 b970bd4f1ed5829e3ee9374c90188c16 496 Gene3D G3DSA:3.40.630.40 319 496 2.9E-60 T 11-10-2018 UP12_16675 b970bd4f1ed5829e3ee9374c90188c16 496 Pfam PF04122 Putative cell wall binding repeat 2 30 116 6.4E-14 T 11-10-2018 IPR007253 Putative cell wall binding repeat 2 UP12_16675 b970bd4f1ed5829e3ee9374c90188c16 496 Pfam PF04122 Putative cell wall binding repeat 2 223 309 1.3E-8 T 11-10-2018 IPR007253 Putative cell wall binding repeat 2 UP12_16675 b970bd4f1ed5829e3ee9374c90188c16 496 Pfam PF04122 Putative cell wall binding repeat 2 129 212 1.2E-12 T 11-10-2018 IPR007253 Putative cell wall binding repeat 2 UP12_16675 b970bd4f1ed5829e3ee9374c90188c16 496 SMART SM00646 380 492 3.9E-43 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_16675 b970bd4f1ed5829e3ee9374c90188c16 496 SUPERFAMILY SSF53187 320 495 5.65E-53 T 11-10-2018 UP12_16675 b970bd4f1ed5829e3ee9374c90188c16 496 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 322 491 1.8E-52 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_09875 02e1323aff87373856f41e515dc6b0a1 131 SUPERFAMILY SSF53098 4 123 1.9E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_09875 02e1323aff87373856f41e515dc6b0a1 131 Pfam PF13456 Reverse transcriptase-like 8 125 9.9E-20 T 11-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 UP12_09875 02e1323aff87373856f41e515dc6b0a1 131 Gene3D G3DSA:3.30.420.10 3 129 4.5E-29 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_00365 250b56c3d1b48e9959cf52386f80ab79 102 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 18 102 4.0E-38 T 11-10-2018 IPR012504 Sporulation protein YabP UP12_00365 250b56c3d1b48e9959cf52386f80ab79 102 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 19 102 5.5E-35 T 11-10-2018 IPR012504 Sporulation protein YabP UP12_00365 250b56c3d1b48e9959cf52386f80ab79 102 Pfam PF07873 YabP family 19 84 2.7E-21 T 11-10-2018 IPR022476 Sporulation protein YabP/YqfC UP12_00365 250b56c3d1b48e9959cf52386f80ab79 102 PIRSF PIRSF011576 1 102 1.8E-53 T 11-10-2018 IPR012504 Sporulation protein YabP UP12_00365 250b56c3d1b48e9959cf52386f80ab79 102 Gene3D G3DSA:2.60.40.2000 27 84 6.9E-24 T 11-10-2018 IPR038705 YabP superfamily UP12_06960 7e1ad63057203f864f6d1e9ca65283ee 397 Pfam PF02687 FtsX-like permease family 303 390 1.2E-11 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UP12_06960 7e1ad63057203f864f6d1e9ca65283ee 397 Pfam PF12704 MacB-like periplasmic core domain 21 236 1.7E-29 T 11-10-2018 IPR025857 MacB-like periplasmic core domain UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 8 700 0.0 T 11-10-2018 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 Gene3D G3DSA:3.20.70.20 152 686 2.3E-185 T 11-10-2018 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 91 163 1.0E-16 T 11-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 SUPERFAMILY SSF48168 8 166 2.88E-49 T 11-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 95 688 9.2E-176 T 11-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 Pfam PF08343 Ribonucleotide reductase N-terminal 9 89 7.9E-30 T 11-10-2018 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 1.5E-26 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 1.5E-26 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 243 262 1.5E-26 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 1.5E-26 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 1.5E-26 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 Gene3D G3DSA:1.10.1650.20 286 338 2.3E-185 T 11-10-2018 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 SUPERFAMILY SSF51998 167 689 1.4E-166 T 11-10-2018 UP12_08460 e755ab8cb02d64ff26a70ed66575e84e 700 Pfam PF02867 Ribonucleotide reductase, barrel domain 168 684 7.5E-137 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 UP12_07060 220353da01c1a726c71de65bc379c2db 371 Pfam PF00676 Dehydrogenase E1 component 53 343 1.9E-100 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UP12_07060 220353da01c1a726c71de65bc379c2db 371 Gene3D G3DSA:3.40.50.970 5 371 1.8E-123 T 11-10-2018 UP12_07060 220353da01c1a726c71de65bc379c2db 371 SUPERFAMILY SSF52518 11 365 1.42E-101 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_07060 220353da01c1a726c71de65bc379c2db 371 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 24 363 2.3E-142 T 11-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 UP12_10355 0394fd4be249b482c616a224490ec1ac 502 SUPERFAMILY SSF52540 57 345 4.83E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10355 0394fd4be249b482c616a224490ec1ac 502 SMART SM00487 13 196 4.4E-22 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_10355 0394fd4be249b482c616a224490ec1ac 502 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 7 367 2.5E-107 T 11-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 UP12_10355 0394fd4be249b482c616a224490ec1ac 502 SMART SM00490 242 324 2.2E-24 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_10355 0394fd4be249b482c616a224490ec1ac 502 Pfam PF00270 DEAD/DEAH box helicase 20 180 3.0E-18 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_10355 0394fd4be249b482c616a224490ec1ac 502 Pfam PF00271 Helicase conserved C-terminal domain 229 323 1.3E-16 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_10355 0394fd4be249b482c616a224490ec1ac 502 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 131 140 - T 11-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site UP12_10355 0394fd4be249b482c616a224490ec1ac 502 Gene3D G3DSA:3.40.50.300 1 198 4.2E-69 T 11-10-2018 UP12_00350 1bd800170cfb37c45fec50bc77ed0463 534 PIRSF PIRSF038958 7 521 5.0E-79 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type UP12_00350 1bd800170cfb37c45fec50bc77ed0463 534 Pfam PF01943 Polysaccharide biosynthesis protein 12 309 2.5E-40 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 UP12_00350 1bd800170cfb37c45fec50bc77ed0463 534 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 505 4.4E-27 T 11-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain UP12_03625 2ae99202952d5537c8465cd97f2a3d90 516 Pfam PF04740 LXG domain of WXG superfamily 2 202 1.3E-61 T 11-10-2018 IPR006829 LXG domain UP12_03625 2ae99202952d5537c8465cd97f2a3d90 516 Pfam PF15542 Bacterial toxin 50 421 513 8.4E-29 T 11-10-2018 IPR029100 Bacterial toxin 50 UP12_03625 2ae99202952d5537c8465cd97f2a3d90 516 Pfam PF14449 Pre-toxin TG 324 390 6.1E-21 T 11-10-2018 IPR027797 Pre-toxin TG domain UP12_03245 c90ab6dcaa533ec6cd5e3900b48776c5 462 Pfam PF00324 Amino acid permease 16 444 1.9E-126 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_03245 c90ab6dcaa533ec6cd5e3900b48776c5 462 Gene3D G3DSA:1.20.1740.10 8 459 6.9E-70 T 11-10-2018 UP12_03245 c90ab6dcaa533ec6cd5e3900b48776c5 462 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 11-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 UP12_03245 c90ab6dcaa533ec6cd5e3900b48776c5 462 PIRSF PIRSF006060 1 461 1.0E-79 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_03245 c90ab6dcaa533ec6cd5e3900b48776c5 462 TIGRFAM TIGR01773 GABAperm: GABA permease 2 447 2.2E-215 T 11-10-2018 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 UP12_08065 09bc59cbcb5ea9d6fdaa0e98e5f90dfd 264 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 220 246 - T 11-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 UP12_08065 09bc59cbcb5ea9d6fdaa0e98e5f90dfd 264 Pfam PF01148 Cytidylyltransferase family 2 262 6.8E-71 T 11-10-2018 UP12_14445 60486ac43f049d1401d9f5db81911117 654 Gene3D G3DSA:3.40.50.300 5 309 3.2E-18 T 11-10-2018 UP12_14445 60486ac43f049d1401d9f5db81911117 654 SUPERFAMILY SSF52540 6 389 1.81E-10 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00125 3fd6bc8d9056eaf643e46f495e33bd88 184 SUPERFAMILY SSF52499 4 181 2.75E-43 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_00125 3fd6bc8d9056eaf643e46f495e33bd88 184 Gene3D G3DSA:3.40.50.850 1 178 4.9E-41 T 11-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 UP12_00125 3fd6bc8d9056eaf643e46f495e33bd88 184 Pfam PF00857 Isochorismatase family 7 175 3.3E-30 T 11-10-2018 IPR000868 Isochorismatase-like GO:0003824 UP12_18090 e20c5945ac8fffbf1cb7e903804f5825 328 Pfam PF01032 FecCD transport family 14 320 1.7E-85 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_18090 e20c5945ac8fffbf1cb7e903804f5825 328 Gene3D G3DSA:1.10.3470.10 2 325 1.4E-87 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_18090 e20c5945ac8fffbf1cb7e903804f5825 328 SUPERFAMILY SSF81345 5 320 1.31E-75 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_14565 06f3c602197dd8ed031792d067fc4648 88 Pfam PF10844 Protein of unknown function (DUF2577) 7 61 5.3E-7 T 11-10-2018 IPR022555 Protein of unknown function, DUF2577 UP12_14565 06f3c602197dd8ed031792d067fc4648 88 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 3 88 3.0E-23 T 11-10-2018 IPR022555 Protein of unknown function, DUF2577 UP12_08700 5461a288675c8d783be314b565a111fa 667 SUPERFAMILY SSF52922 534 666 3.14E-40 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_08700 5461a288675c8d783be314b565a111fa 667 Gene3D G3DSA:3.40.50.970 5 330 1.9E-127 T 11-10-2018 UP12_08700 5461a288675c8d783be314b565a111fa 667 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 338 2.6E-155 T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_08700 5461a288675c8d783be314b565a111fa 667 Gene3D G3DSA:3.40.50.920 540 667 3.6E-39 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 UP12_08700 5461a288675c8d783be314b565a111fa 667 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 4.2E-45 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_08700 5461a288675c8d783be314b565a111fa 667 SUPERFAMILY SSF52518 341 527 3.2E-69 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_08700 5461a288675c8d783be314b565a111fa 667 ProSitePatterns PS00802 Transketolase signature 2. 467 483 - T 11-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_08700 5461a288675c8d783be314b565a111fa 667 Gene3D G3DSA:3.40.50.970 331 537 2.4E-80 T 11-10-2018 UP12_08700 5461a288675c8d783be314b565a111fa 667 TIGRFAM TIGR00232 tktlase_bact: transketolase 7 665 0.0 T 11-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 UP12_08700 5461a288675c8d783be314b565a111fa 667 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 UP12_08700 5461a288675c8d783be314b565a111fa 667 Pfam PF02780 Transketolase, C-terminal domain 550 657 1.3E-9 T 11-10-2018 IPR033248 Transketolase, C-terminal domain UP12_08700 5461a288675c8d783be314b565a111fa 667 SUPERFAMILY SSF52518 8 325 1.47E-117 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_08700 5461a288675c8d783be314b565a111fa 667 SMART SM00861 354 525 1.4E-70 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_14700 f074100ee21f4020884cdab2ee480ed8 380 Pfam PF01594 AI-2E family transporter 32 363 2.0E-84 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like UP12_03730 e3d8dbbd5a2c7791147a095bd8e65c1c 396 Gene3D G3DSA:3.90.550.10 1 268 3.9E-58 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_03730 e3d8dbbd5a2c7791147a095bd8e65c1c 396 SUPERFAMILY SSF53448 2 277 5.91E-46 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_03730 e3d8dbbd5a2c7791147a095bd8e65c1c 396 Pfam PF00535 Glycosyl transferase family 2 8 127 3.2E-27 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_08390 01212f28418367799dbfe05d18902e94 382 SUPERFAMILY SSF48452 133 282 1.38E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_08390 01212f28418367799dbfe05d18902e94 382 Gene3D G3DSA:1.25.40.10 1 380 1.4E-115 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_08390 01212f28418367799dbfe05d18902e94 382 SMART SM00028 224 257 0.0021 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_08390 01212f28418367799dbfe05d18902e94 382 SMART SM00028 139 172 19.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_08390 01212f28418367799dbfe05d18902e94 382 Pfam PF13374 Tetratricopeptide repeat 224 256 5.5E-5 T 11-10-2018 UP12_16880 a307ce95d64ac1f7886d8dc498a9db6e 380 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 209 377 9.9E-24 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_16880 a307ce95d64ac1f7886d8dc498a9db6e 380 Gene3D G3DSA:3.30.300.210 233 380 2.7E-17 T 11-10-2018 IPR038501 Spore germination GerAC superfamily UP12_16880 a307ce95d64ac1f7886d8dc498a9db6e 380 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 5 379 7.4E-68 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_02225 eab71a663d1b781c88edf624d5301eb8 79 Pfam PF10852 Protein of unknown function (DUF2651) 7 74 4.3E-11 T 11-10-2018 IPR020258 Uncharacterised protein family YbeF UP12_03150 efe738c1f578a489459572a7687a0fa4 163 Pfam PF01967 MoaC family 15 152 2.8E-52 T 11-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_03150 efe738c1f578a489459572a7687a0fa4 163 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 3.5E-65 T 11-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_03150 efe738c1f578a489459572a7687a0fa4 163 Gene3D G3DSA:3.30.70.640 1 162 6.1E-68 T 11-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_03150 efe738c1f578a489459572a7687a0fa4 163 SUPERFAMILY SSF55040 11 157 4.45E-56 T 11-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_03150 efe738c1f578a489459572a7687a0fa4 163 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 160 35.387 T 11-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 UP12_04350 7825742dc500c7cec7a99abe4daa2f0c 66 Pfam PF12645 Helix-turn-helix domain 6 45 6.4E-5 T 11-10-2018 IPR024760 Helix-turn-helix, conjugative transposon-like UP12_00210 255b07713fb2216f8f5a2e405d1a90c1 109 SUPERFAMILY SSF54913 1 107 5.4E-12 T 11-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta UP12_00210 255b07713fb2216f8f5a2e405d1a90c1 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 1.7E-53 T 11-10-2018 IPR010375 Cyclic-di-AMP receptor UP12_00210 255b07713fb2216f8f5a2e405d1a90c1 109 Gene3D G3DSA:3.30.70.120 1 103 1.3E-43 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_17455 98ea90b2a3a013d22076508fe5129474 290 Gene3D G3DSA:3.40.800.10 17 290 5.3E-96 T 11-10-2018 UP12_17455 98ea90b2a3a013d22076508fe5129474 290 TIGRFAM TIGR01230 agmatinase: agmatinase 10 286 6.3E-119 T 11-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 UP12_17455 98ea90b2a3a013d22076508fe5129474 290 Pfam PF00491 Arginase family 23 285 9.3E-81 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_17455 98ea90b2a3a013d22076508fe5129474 290 PIRSF PIRSF036979 1 290 1.8E-97 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 UP12_17455 98ea90b2a3a013d22076508fe5129474 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 11-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 UP12_17455 98ea90b2a3a013d22076508fe5129474 290 SUPERFAMILY SSF52768 12 288 4.32E-87 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily UP12_05065 e40c035af38b68d8eafb09dead9d27f5 28 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 4 26 1.7E-13 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_05065 e40c035af38b68d8eafb09dead9d27f5 28 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 2 27 1.4E-14 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_03465 4ffba938fca543dd993377fa15078316 230 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 28.587 T 11-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 UP12_03465 4ffba938fca543dd993377fa15078316 230 Gene3D G3DSA:3.20.20.390 1 230 2.3E-95 T 11-10-2018 IPR038597 GGGP/HepGP synthase superfamily UP12_03465 4ffba938fca543dd993377fa15078316 230 Pfam PF01884 PcrB family 2 226 2.9E-89 T 11-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 UP12_03465 4ffba938fca543dd993377fa15078316 230 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 9 223 5.0E-73 T 11-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 UP12_03465 4ffba938fca543dd993377fa15078316 230 SUPERFAMILY SSF51395 6 221 6.77E-52 T 11-10-2018 UP12_18120 0e219a1aaf40df54cd52354f77f91c04 297 Gene3D G3DSA:3.10.180.10 168 289 1.4E-11 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_18120 0e219a1aaf40df54cd52354f77f91c04 297 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 122 3.0E-12 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_18120 0e219a1aaf40df54cd52354f77f91c04 297 SUPERFAMILY SSF54593 7 168 3.16E-35 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_18120 0e219a1aaf40df54cd52354f77f91c04 297 SUPERFAMILY SSF54593 177 279 4.23E-15 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_18120 0e219a1aaf40df54cd52354f77f91c04 297 Gene3D G3DSA:3.10.180.10 7 135 1.9E-25 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_06935 e9ef69af8a3bcc61c726e7b90f311a63 77 Gene3D G3DSA:3.10.20.30 1 77 6.8E-19 T 11-10-2018 IPR012675 Beta-grasp domain superfamily UP12_06935 e9ef69af8a3bcc61c726e7b90f311a63 77 Pfam PF02597 ThiS family 4 77 3.8E-16 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 UP12_06935 e9ef69af8a3bcc61c726e7b90f311a63 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 7.8E-21 T 11-10-2018 UP12_06935 e9ef69af8a3bcc61c726e7b90f311a63 77 SUPERFAMILY SSF54285 2 77 5.79E-15 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp UP12_11890 b3b73e547a2d3cc741d2e6ecd17ed6b0 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 UP12_11890 b3b73e547a2d3cc741d2e6ecd17ed6b0 307 Gene3D G3DSA:3.40.50.1100 10 299 5.5E-112 T 11-10-2018 UP12_11890 b3b73e547a2d3cc741d2e6ecd17ed6b0 307 Gene3D G3DSA:3.40.50.1100 45 146 5.5E-112 T 11-10-2018 UP12_11890 b3b73e547a2d3cc741d2e6ecd17ed6b0 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 8.5E-65 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UP12_11890 b3b73e547a2d3cc741d2e6ecd17ed6b0 307 SUPERFAMILY SSF53686 3 300 5.76E-90 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 Pfam PF01336 OB-fold nucleic acid binding domain 65 142 3.9E-16 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 SUPERFAMILY SSF55681 158 497 6.7E-124 T 11-10-2018 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 Pfam PF00152 tRNA synthetases class II (D, K and N) 159 496 6.8E-84 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 SUPERFAMILY SSF50249 10 151 5.57E-46 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 Gene3D G3DSA:2.40.50.140 11 151 2.4E-47 T 11-10-2018 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 211 227 2.1E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 240 253 2.1E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 258 275 2.1E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 195 205 2.1E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 PRINTS PR00982 Lysyl-tRNA synthetase signature 381 397 2.1E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 Gene3D G3DSA:3.30.930.10 152 496 5.7E-139 T 11-10-2018 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 PIRSF PIRSF039101 2 499 3.0E-204 T 11-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 10 498 1.7E-229 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_00485 81f699bee4bcb56e6ee091e00e4a77a3 499 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 17 499 46.294 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 Pfam PF02073 Thermophilic metalloprotease (M29) 5 408 1.8E-176 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 Gene3D G3DSA:3.40.1830.10 1 179 1.7E-66 T 11-10-2018 IPR035097 Peptidase M29, N-terminal UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 15 32 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 80 99 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 324 345 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 156 178 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 389 408 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 363 385 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 245 264 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 301 321 1.5E-73 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 UP12_06995 94ed0b0017476f701bf0b6919aa8942c 410 SUPERFAMILY SSF144052 4 409 4.58E-151 T 11-10-2018 UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 13 393 1.6E-97 T 11-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 PRINTS PR01035 Tetracycline resistance protein signature 284 305 1.1E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 PRINTS PR01035 Tetracycline resistance protein signature 111 132 1.1E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 PRINTS PR01035 Tetracycline resistance protein signature 27 43 1.1E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 PRINTS PR01035 Tetracycline resistance protein signature 171 191 1.1E-6 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 Pfam PF07690 Major Facilitator Superfamily 24 360 3.8E-47 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 SUPERFAMILY SSF103473 8 403 1.83E-62 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01475 417f0dcdff339adcd73c6d02694cbb07 405 Gene3D G3DSA:1.20.1720.10 17 395 1.9E-99 T 11-10-2018 UP12_05800 ead7fa9d6e31993baa0dd3167bc2e90e 247 Pfam PF00149 Calcineurin-like phosphoesterase 1 195 2.0E-12 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 UP12_05800 ead7fa9d6e31993baa0dd3167bc2e90e 247 Gene3D G3DSA:3.60.21.10 1 246 4.4E-56 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_05800 ead7fa9d6e31993baa0dd3167bc2e90e 247 SUPERFAMILY SSF56300 1 237 3.51E-35 T 11-10-2018 UP12_02595 83387a62f9303ce4a71450ab2dc02881 157 Hamap MF_00745 Protein SprT-like. 4 151 39.464 T 11-10-2018 IPR023524 Uncharacterised protein family SprT-like UP12_02595 83387a62f9303ce4a71450ab2dc02881 157 SMART SM00731 4 151 6.8E-56 T 11-10-2018 IPR006640 SprT-like UP12_02595 83387a62f9303ce4a71450ab2dc02881 157 Pfam PF10263 SprT-like family 7 97 5.9E-14 T 11-10-2018 IPR006640 SprT-like UP12_02595 83387a62f9303ce4a71450ab2dc02881 157 Pfam PF17283 SprT-like zinc ribbon domain 118 149 4.5E-8 T 11-10-2018 IPR035240 SprT-like, zinc ribbon domain UP12_03925 e9621b99488a4e594727df55f5558da3 167 Pfam PF07681 DoxX 16 115 4.4E-11 T 11-10-2018 IPR032808 DoxX family UP12_18010 bb44d6b4232cbfb65d7a0cecc1908eef 204 Gene3D G3DSA:2.40.260.10 17 204 1.6E-29 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_18010 bb44d6b4232cbfb65d7a0cecc1908eef 204 Pfam PF04203 Sortase family 64 201 3.1E-19 T 11-10-2018 IPR005754 Sortase family UP12_18010 bb44d6b4232cbfb65d7a0cecc1908eef 204 SUPERFAMILY SSF63817 60 202 2.35E-16 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_11025 f92f572ac309f61d8c1bf8e1f877b17b 397 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 72 390 1.0E-108 T 11-10-2018 IPR014194 Sporulation stage III, protein AE UP12_11025 f92f572ac309f61d8c1bf8e1f877b17b 397 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 1 390 9.6E-150 T 11-10-2018 IPR014194 Sporulation stage III, protein AE UP12_03820 746792c0310f73ed20673133288bc624 129 Gene3D G3DSA:1.10.8.570 1 112 3.9E-42 T 11-10-2018 IPR038074 YfmB domain superfamily UP12_03820 746792c0310f73ed20673133288bc624 129 Pfam PF11486 Protein of unknown function (DUF3212) 1 118 6.2E-65 T 11-10-2018 IPR021579 Protein of unknown function DUF3212 UP12_03820 746792c0310f73ed20673133288bc624 129 SUPERFAMILY SSF140688 1 111 1.05E-55 T 11-10-2018 IPR038074 YfmB domain superfamily UP12_18580 2804581dce6c6123b47d596a4be57df2 370 Gene3D G3DSA:1.10.10.2840 245 370 1.4E-20 T 11-10-2018 UP12_18580 2804581dce6c6123b47d596a4be57df2 370 Pfam PF05651 Putative sugar diacid recognition 4 137 5.7E-49 T 11-10-2018 IPR008599 Putative sugar diacid recognition UP12_18580 2804581dce6c6123b47d596a4be57df2 370 Pfam PF13556 PucR C-terminal helix-turn-helix domain 308 363 9.4E-19 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_07275 1d262f00c0150828113dab086149c9ba 185 Gene3D G3DSA:3.40.50.150 1 185 1.1E-57 T 11-10-2018 UP12_07275 1d262f00c0150828113dab086149c9ba 185 SUPERFAMILY SSF53335 1 181 5.72E-48 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_07275 1d262f00c0150828113dab086149c9ba 185 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 117 123 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 UP12_07275 1d262f00c0150828113dab086149c9ba 185 PIRSF PIRSF004553 1 183 5.7E-50 T 11-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 UP12_07275 1d262f00c0150828113dab086149c9ba 185 Pfam PF03602 Conserved hypothetical protein 95 1 181 4.0E-58 T 11-10-2018 UP12_07275 1d262f00c0150828113dab086149c9ba 185 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 181 4.8E-59 T 11-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 SUPERFAMILY SSF53756 165 409 1.83E-15 T 11-10-2018 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 42 409 2.3E-92 T 11-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 Gene3D G3DSA:3.40.50.2000 630 823 7.4E-44 T 11-10-2018 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 SUPERFAMILY SSF53756 434 836 1.97E-47 T 11-10-2018 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 Pfam PF00534 Glycosyl transferases group 1 675 827 1.5E-32 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 Gene3D G3DSA:3.40.50.11820 42 402 6.9E-126 T 11-10-2018 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 Gene3D G3DSA:3.40.50.12580 220 395 6.9E-126 T 11-10-2018 UP12_16715 3e156d9e2558336264f4a7c40613af11 845 Gene3D G3DSA:3.40.50.2000 436 629 7.4E-44 T 11-10-2018 UP12_13870 9a7d5f9ef25f29776feb3c576126b4e2 443 PIRSF PIRSF006446 1 443 4.5E-109 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UP12_13870 9a7d5f9ef25f29776feb3c576126b4e2 443 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 431 8.1E-119 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 UP12_09165 96674d15adf2658b937164dc84ba9d03 295 Pfam PF13350 Tyrosine phosphatase family 33 283 7.2E-61 T 11-10-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type UP12_09165 96674d15adf2658b937164dc84ba9d03 295 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 173 183 - T 11-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 UP12_09165 96674d15adf2658b937164dc84ba9d03 295 SUPERFAMILY SSF52799 34 283 8.98E-45 T 11-10-2018 IPR029021 Protein-tyrosine phosphatase-like UP12_09165 96674d15adf2658b937164dc84ba9d03 295 Gene3D G3DSA:3.90.190.10 34 283 7.0E-58 T 11-10-2018 IPR029021 Protein-tyrosine phosphatase-like UP12_06955 cd8898fb755645522da40cb59b99f73d 233 Gene3D G3DSA:3.40.50.300 1 231 1.6E-66 T 11-10-2018 UP12_06955 cd8898fb755645522da40cb59b99f73d 233 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_06955 cd8898fb755645522da40cb59b99f73d 233 Pfam PF00005 ABC transporter 21 169 1.9E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_06955 cd8898fb755645522da40cb59b99f73d 233 SMART SM00382 30 217 4.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_06955 cd8898fb755645522da40cb59b99f73d 233 SUPERFAMILY SSF52540 1 222 3.06E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_12740 7e1867093f296c8089143c8c9dc7eeab 419 Gene3D G3DSA:3.40.50.150 10 196 1.0E-42 T 11-10-2018 UP12_12740 7e1867093f296c8089143c8c9dc7eeab 419 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 115 129 6.1E-9 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_12740 7e1867093f296c8089143c8c9dc7eeab 419 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 10 26 6.1E-9 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_12740 7e1867093f296c8089143c8c9dc7eeab 419 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 173 186 6.1E-9 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_12740 7e1867093f296c8089143c8c9dc7eeab 419 Gene3D G3DSA:3.90.120.10 334 392 2.3E-8 T 11-10-2018 UP12_12740 7e1867093f296c8089143c8c9dc7eeab 419 SUPERFAMILY SSF53335 11 399 8.72E-69 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_12740 7e1867093f296c8089143c8c9dc7eeab 419 Pfam PF00145 C-5 cytosine-specific DNA methylase 11 399 3.1E-26 T 11-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 UP12_08710 b1d5a88bb239b6d9fee9e123247fe056 72 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 69 2.1E-30 T 11-10-2018 IPR005359 Protein with unknown function UPF0154 UP12_08710 b1d5a88bb239b6d9fee9e123247fe056 72 Hamap MF_00363 UPF0154 protein . 2 72 22.371 T 11-10-2018 IPR005359 Protein with unknown function UPF0154 UP12_08710 b1d5a88bb239b6d9fee9e123247fe056 72 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 41 0.003 T 11-10-2018 IPR005359 Protein with unknown function UPF0154 UP12_08540 45dd7da68b50f4990602369704ee263b 153 SUPERFAMILY SSF52949 1 152 1.4E-40 T 11-10-2018 UP12_08540 45dd7da68b50f4990602369704ee263b 153 Pfam PF01661 Macro domain 19 137 5.2E-12 T 11-10-2018 IPR002589 Macro domain UP12_08540 45dd7da68b50f4990602369704ee263b 153 Gene3D G3DSA:3.40.220.10 1 153 2.5E-48 T 11-10-2018 UP12_08540 45dd7da68b50f4990602369704ee263b 153 SMART SM00506 1 138 3.7E-6 T 11-10-2018 IPR002589 Macro domain UP12_01585 4bc1d148622cef53f579f8af8d00a562 233 Gene3D G3DSA:3.40.50.2300 1 125 2.1E-27 T 11-10-2018 UP12_01585 4bc1d148622cef53f579f8af8d00a562 233 Gene3D G3DSA:2.40.50.1020 126 226 6.3E-14 T 11-10-2018 UP12_01585 4bc1d148622cef53f579f8af8d00a562 233 Pfam PF04397 LytTr DNA-binding domain 136 230 2.1E-20 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UP12_01585 4bc1d148622cef53f579f8af8d00a562 233 SMART SM00850 135 233 3.9E-20 T 11-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 UP12_01585 4bc1d148622cef53f579f8af8d00a562 233 SUPERFAMILY SSF52172 1 122 7.68E-26 T 11-10-2018 IPR011006 CheY-like superfamily UP12_01585 4bc1d148622cef53f579f8af8d00a562 233 SMART SM00448 2 113 4.7E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_01585 4bc1d148622cef53f579f8af8d00a562 233 Pfam PF00072 Response regulator receiver domain 6 113 1.4E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_14655 92608e277bef8411fbcfc81dab274ee2 68 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 11 62 1.0E-12 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA UP12_14655 92608e277bef8411fbcfc81dab274ee2 68 Pfam PF17356 Phage-like element PBSX protein XtrA 3 67 7.9E-25 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA UP12_08935 c38d701e21ba5e368434a007dde844e2 381 SUPERFAMILY SSF53474 27 355 7.22E-16 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_08935 c38d701e21ba5e368434a007dde844e2 381 Gene3D G3DSA:3.40.50.1820 2 380 2.1E-55 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_08935 c38d701e21ba5e368434a007dde844e2 381 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 7 325 3.0E-15 T 11-10-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 5.9E-42 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 5.9E-42 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.9E-42 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.9E-42 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 5.9E-42 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 5.9E-42 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 25 254 4.7E-63 T 11-10-2018 UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 SUPERFAMILY SSF51735 14 256 9.04E-79 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.4E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 2.4E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.4E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 11 257 2.5E-118 T 11-10-2018 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.127|MetaCyc: PWY-6507|MetaCyc: PWY-7562 UP12_16810 d66bbf1d875d7cbdbb1f2a46d651a8fa 257 Gene3D G3DSA:3.40.50.720 1 256 6.2E-79 T 11-10-2018 UP12_08255 0d80674525ba296d1019f6b5ba47e8e5 158 SMART SM00347 29 129 2.5E-21 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_08255 0d80674525ba296d1019f6b5ba47e8e5 158 SUPERFAMILY SSF46785 12 146 3.13E-27 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_08255 0d80674525ba296d1019f6b5ba47e8e5 158 Gene3D G3DSA:1.10.10.10 3 158 6.8E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08255 0d80674525ba296d1019f6b5ba47e8e5 158 Pfam PF01047 MarR family 36 94 1.6E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_18550 a726de9356a4e10129c3175940980abd 317 Pfam PF12679 ABC-2 family transporter protein 4 312 1.1E-19 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 Gene3D G3DSA:3.40.190.290 91 285 2.2E-31 T 11-10-2018 UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 SUPERFAMILY SSF53850 88 282 2.71E-33 T 11-10-2018 UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 SUPERFAMILY SSF46785 2 109 5.75E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 7.1E-20 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 Gene3D G3DSA:1.10.10.10 1 90 1.5E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06460 50d8f1bafa62162f2ff0b1617b3c2f38 287 Pfam PF03466 LysR substrate binding domain 86 282 1.2E-37 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_14280 480aa43df842a0c69aef207298f25942 439 Gene3D G3DSA:3.40.50.300 8 235 1.8E-58 T 11-10-2018 UP12_14280 480aa43df842a0c69aef207298f25942 439 Pfam PF04466 Phage terminase large subunit 22 234 5.9E-79 T 11-10-2018 IPR035412 Phage terminase large subunit, N-terminal UP12_14280 480aa43df842a0c69aef207298f25942 439 Pfam PF17288 Terminase RNAseH like domain 271 413 2.0E-43 T 11-10-2018 IPR035413 Phage terminase large subunit, C-terminal UP12_14280 480aa43df842a0c69aef207298f25942 439 Gene3D G3DSA:3.30.420.280 246 418 1.2E-34 T 11-10-2018 UP12_14280 480aa43df842a0c69aef207298f25942 439 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 22 421 1.6E-101 T 11-10-2018 IPR006437 Bacteriophage terminase, large subunit GO:0006323 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 297 320 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 Pfam PF00375 Sodium:dicarboxylate symporter family 7 402 2.7E-123 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 Gene3D G3DSA:1.10.3860.10 1 421 3.4E-134 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 3.8E-37 T 11-10-2018 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 3.8E-37 T 11-10-2018 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 3.8E-37 T 11-10-2018 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 PRINTS PR00173 Glutamate-aspartate symporter signature 329 348 3.8E-37 T 11-10-2018 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 PRINTS PR00173 Glutamate-aspartate symporter signature 356 376 3.8E-37 T 11-10-2018 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 3.8E-37 T 11-10-2018 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 3.8E-37 T 11-10-2018 UP12_15760 d1ba23f53f1c9a970a96f23c4148d8a3 425 SUPERFAMILY SSF118215 6 403 1.11E-124 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_13270 277fafb54685be1d67a01f9ae5701552 415 Pfam PF01098 Cell cycle protein 293 402 9.3E-19 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_13270 277fafb54685be1d67a01f9ae5701552 415 Pfam PF01098 Cell cycle protein 82 272 2.9E-10 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_03505 375c3addfeb653d8ad4d82df44bd0554 236 SUPERFAMILY SSF53474 3 224 3.49E-44 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_03505 375c3addfeb653d8ad4d82df44bd0554 236 Gene3D G3DSA:3.40.50.1820 1 233 1.7E-56 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_03505 375c3addfeb653d8ad4d82df44bd0554 236 Pfam PF00975 Thioesterase domain 2 225 9.7E-41 T 11-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UP12_00360 5c809c447dea61a72932165271a8fbd9 86 Pfam PF01479 S4 domain 1 47 1.9E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00360 5c809c447dea61a72932165271a8fbd9 86 SUPERFAMILY SSF55174 1 76 1.57E-19 T 11-10-2018 UP12_00360 5c809c447dea61a72932165271a8fbd9 86 SMART SM00363 1 63 3.2E-8 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00360 5c809c447dea61a72932165271a8fbd9 86 Gene3D G3DSA:3.10.290.10 1 86 2.2E-24 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 UP12_00360 5c809c447dea61a72932165271a8fbd9 86 PIRSF PIRSF038881 1 86 2.0E-34 T 11-10-2018 IPR025490 RNA-binding protein, HP1423 type UP12_08135 fe4fa259e454850f09b8bd4666e93003 92 SUPERFAMILY SSF103007 1 92 2.09E-30 T 11-10-2018 IPR036746 TT1725-like superfamily UP12_08135 fe4fa259e454850f09b8bd4666e93003 92 Pfam PF04456 Protein of unknown function (DUF503) 2 86 8.8E-31 T 11-10-2018 IPR007546 Protein of unknown function DUF503 UP12_08135 fe4fa259e454850f09b8bd4666e93003 92 Gene3D G3DSA:3.30.70.1120 1 92 1.2E-24 T 11-10-2018 IPR036746 TT1725-like superfamily UP12_05795 a1a1f43a27a7baa4d0deb6c8fd0f4417 288 Gene3D G3DSA:3.30.2350.10 74 288 4.6E-65 T 11-10-2018 UP12_05795 a1a1f43a27a7baa4d0deb6c8fd0f4417 288 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 124 138 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_05795 a1a1f43a27a7baa4d0deb6c8fd0f4417 288 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 32 287 3.1E-72 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_05795 a1a1f43a27a7baa4d0deb6c8fd0f4417 288 SUPERFAMILY SSF55120 66 286 8.96E-67 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_05795 a1a1f43a27a7baa4d0deb6c8fd0f4417 288 Pfam PF00849 RNA pseudouridylate synthase 81 233 8.4E-27 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_14195 54265cb7bdb2bf529f4ec013c68dd3c4 220 Gene3D G3DSA:3.10.350.10 161 218 2.5E-13 T 11-10-2018 IPR036779 LysM domain superfamily UP12_14195 54265cb7bdb2bf529f4ec013c68dd3c4 220 SUPERFAMILY SSF54106 160 219 5.23E-7 T 11-10-2018 UP12_14195 54265cb7bdb2bf529f4ec013c68dd3c4 220 SMART SM00257 161 219 2.2E-8 T 11-10-2018 IPR018392 LysM domain UP12_14195 54265cb7bdb2bf529f4ec013c68dd3c4 220 Pfam PF01476 LysM domain 162 219 5.2E-20 T 11-10-2018 IPR018392 LysM domain UP12_08645 20afbd9120ad82e9aa9128a520fe4753 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_08645 20afbd9120ad82e9aa9128a520fe4753 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 2.2E-17 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08645 20afbd9120ad82e9aa9128a520fe4753 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.6E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08645 20afbd9120ad82e9aa9128a520fe4753 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.6E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08645 20afbd9120ad82e9aa9128a520fe4753 193 Gene3D G3DSA:1.10.357.10 2 190 3.1E-46 T 11-10-2018 UP12_08645 20afbd9120ad82e9aa9128a520fe4753 193 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 59 191 8.9E-30 T 11-10-2018 IPR032551 HTH-type transcriptional repressor, C-terminal UP12_08645 20afbd9120ad82e9aa9128a520fe4753 193 SUPERFAMILY SSF46689 6 70 3.39E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_04855 63883daf2484083a4b8360e022844d8e 454 Pfam PF00245 Alkaline phosphatase 47 451 4.3E-123 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_04855 63883daf2484083a4b8360e022844d8e 454 SUPERFAMILY SSF53649 39 452 9.16E-120 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_04855 63883daf2484083a4b8360e022844d8e 454 Gene3D G3DSA:1.10.60.40 328 413 1.4E-138 T 11-10-2018 UP12_04855 63883daf2484083a4b8360e022844d8e 454 ProSitePatterns PS00123 Alkaline phosphatase active site. 99 107 - T 11-10-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_04855 63883daf2484083a4b8360e022844d8e 454 PRINTS PR00113 Alkaline phosphatase signature 136 156 7.5E-40 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_04855 63883daf2484083a4b8360e022844d8e 454 PRINTS PR00113 Alkaline phosphatase signature 46 66 7.5E-40 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_04855 63883daf2484083a4b8360e022844d8e 454 PRINTS PR00113 Alkaline phosphatase signature 252 281 7.5E-40 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_04855 63883daf2484083a4b8360e022844d8e 454 PRINTS PR00113 Alkaline phosphatase signature 186 196 7.5E-40 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_04855 63883daf2484083a4b8360e022844d8e 454 PRINTS PR00113 Alkaline phosphatase signature 99 114 7.5E-40 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_04855 63883daf2484083a4b8360e022844d8e 454 Gene3D G3DSA:3.40.720.10 50 443 1.4E-138 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_04855 63883daf2484083a4b8360e022844d8e 454 SMART SM00098 47 454 3.7E-170 T 11-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 UP12_10360 157483adec7ff0283ff492543d9e0982 350 PIRSF PIRSF021350 4 350 2.8E-96 T 11-10-2018 IPR008308 Uncharacterised conserved protein UCP021350 UP12_10360 157483adec7ff0283ff492543d9e0982 350 Pfam PF14493 Helix-turn-helix domain 255 342 7.5E-22 T 11-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 TIGRFAM TIGR03063 srtB_target: sortase B cell surface sorting signal 573 600 3.0E-8 T 11-10-2018 IPR017502 Sortase B cell surface sorting signal UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 SUPERFAMILY SSF158911 223 352 1.31E-37 T 11-10-2018 IPR037250 NEAT domain superfamily UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 Gene3D G3DSA:2.60.40.1850 374 506 8.1E-35 T 11-10-2018 UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 Gene3D G3DSA:2.60.40.1850 20 155 5.6E-47 T 11-10-2018 UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 Gene3D G3DSA:2.60.40.1850 215 350 3.8E-41 T 11-10-2018 UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 Pfam PF05031 Iron Transport-associated domain 36 150 5.8E-34 T 11-10-2018 IPR006635 NEAT domain UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 Pfam PF05031 Iron Transport-associated domain 228 345 7.6E-34 T 11-10-2018 IPR006635 NEAT domain UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 Pfam PF05031 Iron Transport-associated domain 387 502 1.2E-27 T 11-10-2018 IPR006635 NEAT domain UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 SUPERFAMILY SSF158911 381 508 7.32E-35 T 11-10-2018 IPR037250 NEAT domain superfamily UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 SUPERFAMILY SSF158911 23 163 1.28E-38 T 11-10-2018 IPR037250 NEAT domain superfamily UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 SMART SM00725 388 509 1.2E-24 T 11-10-2018 IPR006635 NEAT domain UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 SMART SM00725 36 157 2.5E-37 T 11-10-2018 IPR006635 NEAT domain UP12_18100 edb543707e0c5a19aeff9196509ccbbb 605 SMART SM00725 230 351 2.0E-35 T 11-10-2018 IPR006635 NEAT domain UP12_07475 c1f2cf38a1f98a6c1b7447f1d68b92cb 78 SUPERFAMILY SSF50346 1 74 4.45E-14 T 11-10-2018 IPR011033 PRC-barrel-like superfamily UP12_07475 c1f2cf38a1f98a6c1b7447f1d68b92cb 78 Pfam PF05239 PRC-barrel domain 2 75 3.9E-14 T 11-10-2018 IPR027275 PRC-barrel domain UP12_07475 c1f2cf38a1f98a6c1b7447f1d68b92cb 78 Gene3D G3DSA:2.30.30.240 1 76 7.5E-14 T 11-10-2018 UP12_07475 c1f2cf38a1f98a6c1b7447f1d68b92cb 78 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 4 75 2.8E-26 T 11-10-2018 IPR014238 Sporulation protein YlmC/YmxH UP12_06065 9dbf183b7593906b40e5a2c0aaaf00ee 173 PIRSF PIRSF031551 1 173 3.2E-54 T 11-10-2018 IPR012550 Protein of unknown function DUF1706 UP12_06065 9dbf183b7593906b40e5a2c0aaaf00ee 173 Pfam PF08020 Protein of unknown function (DUF1706) 1 169 8.1E-51 T 11-10-2018 IPR012550 Protein of unknown function DUF1706 UP12_06065 9dbf183b7593906b40e5a2c0aaaf00ee 173 Gene3D G3DSA:1.20.120.450 1 171 5.5E-68 T 11-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes UP12_18455 4f2e07e512efbdf34d846d40c08fd5ff 368 Gene3D G3DSA:1.25.40.290 124 240 6.1E-38 T 11-10-2018 UP12_18455 4f2e07e512efbdf34d846d40c08fd5ff 368 Pfam PF08713 DNA alkylation repair enzyme 125 236 1.4E-4 T 11-10-2018 IPR014825 DNA alkylation repair enzyme UP12_18455 4f2e07e512efbdf34d846d40c08fd5ff 368 SUPERFAMILY SSF48371 45 240 6.4E-46 T 11-10-2018 IPR016024 Armadillo-type fold UP12_08105 9fa486ebb5fccf386b154759166561ee 377 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 42 335 1.0E-16 T 11-10-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 UP12_08105 9fa486ebb5fccf386b154759166561ee 377 SUPERFAMILY SSF51445 31 353 7.72E-82 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_08105 9fa486ebb5fccf386b154759166561ee 377 Gene3D G3DSA:3.20.20.80 29 375 3.8E-127 T 11-10-2018 UP12_06345 bc0e6877b2da05413e819ef26c00274b 181 Pfam PF13302 Acetyltransferase (GNAT) domain 13 153 1.6E-34 T 11-10-2018 IPR000182 GNAT domain UP12_06345 bc0e6877b2da05413e819ef26c00274b 181 Gene3D G3DSA:3.40.630.30 1 178 5.2E-44 T 11-10-2018 UP12_06345 bc0e6877b2da05413e819ef26c00274b 181 SUPERFAMILY SSF55729 6 162 1.81E-39 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_12115 c767c333a6bc6bedfd5b0be7e812255a 516 PIRSF PIRSF038958 1 516 1.3E-185 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type UP12_12115 c767c333a6bc6bedfd5b0be7e812255a 516 Pfam PF01943 Polysaccharide biosynthesis protein 6 308 8.8E-64 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 UP12_12115 c767c333a6bc6bedfd5b0be7e812255a 516 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 360 499 1.6E-15 T 11-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain UP12_12115 c767c333a6bc6bedfd5b0be7e812255a 516 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 6 494 1.0E-178 T 11-10-2018 IPR014249 Sporulation stage V protein B UP12_19145 c12098a5952877868e3288f929d938f1 274 SUPERFAMILY SSF54001 123 234 1.35E-10 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_19145 c12098a5952877868e3288f929d938f1 274 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 137 262 6.7E-7 T 11-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family UP12_16855 32c385d95b6262e9cdcac06216c80b37 388 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 61 299 3.8E-76 T 11-10-2018 IPR019079 Capsule synthesis protein, CapA UP12_16855 32c385d95b6262e9cdcac06216c80b37 388 Gene3D G3DSA:3.60.21.10 90 324 5.2E-13 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like UP12_16855 32c385d95b6262e9cdcac06216c80b37 388 SUPERFAMILY SSF56300 60 315 2.46E-40 T 11-10-2018 UP12_16855 32c385d95b6262e9cdcac06216c80b37 388 SMART SM00854 60 299 7.0E-97 T 11-10-2018 IPR019079 Capsule synthesis protein, CapA UP12_12790 effdb91c4a32a6365c5f51a94843565e 438 Pfam PF03600 Citrate transporter 13 383 2.3E-47 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 UP12_12790 effdb91c4a32a6365c5f51a94843565e 438 TIGRFAM TIGR00784 citMHS: citrate transporter 2 437 5.3E-193 T 11-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 Pfam PF02610 L-arabinose isomerase 5 357 4.2E-166 T 11-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 Pfam PF11762 L-arabinose isomerase C-terminal domain 360 472 2.2E-42 T 11-10-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 Hamap MF_00519 L-arabinose isomerase [araA]. 1 473 58.702 T 11-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 SUPERFAMILY SSF53743 1 327 2.62E-120 T 11-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 SUPERFAMILY SSF50443 327 473 4.97E-56 T 11-10-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 Gene3D G3DSA:3.40.50.10940 1 175 1.5E-83 T 11-10-2018 IPR038583 L-arabinose isomerase, N-terminal domain superfamily KEGG: 00040+5.3.1.4 UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 1 303 8.0E-145 T 11-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 UP12_11750 10ffe9db1152568918ff1de6b0e51b4e 473 PIRSF PIRSF001478 1 473 1.9E-229 T 11-10-2018 IPR003762 L-arabinose isomerase GO:0008733 KEGG: 00040+5.3.1.4 UP12_13310 e8f91f9c002381a545379ace78f8b230 526 Gene3D G3DSA:3.40.50.12780 2 416 5.7E-106 T 11-10-2018 UP12_13310 e8f91f9c002381a545379ace78f8b230 526 SUPERFAMILY SSF56801 22 522 9.68E-138 T 11-10-2018 UP12_13310 e8f91f9c002381a545379ace78f8b230 526 Pfam PF00501 AMP-binding enzyme 25 423 4.4E-79 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_13310 e8f91f9c002381a545379ace78f8b230 526 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_13310 e8f91f9c002381a545379ace78f8b230 526 Gene3D G3DSA:3.30.300.310 419 524 4.5E-30 T 11-10-2018 UP12_13310 e8f91f9c002381a545379ace78f8b230 526 Pfam PF13193 AMP-binding enzyme C-terminal domain 432 510 3.1E-24 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_15900 abcf75c391d4ecc4fb67224509e30923 255 Gene3D G3DSA:3.40.50.300 3 242 1.1E-41 T 11-10-2018 UP12_15900 abcf75c391d4ecc4fb67224509e30923 255 SMART SM00382 26 208 1.4E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15900 abcf75c391d4ecc4fb67224509e30923 255 Pfam PF00005 ABC transporter 17 160 3.2E-20 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15900 abcf75c391d4ecc4fb67224509e30923 255 SUPERFAMILY SSF52540 9 218 3.26E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 149 699 2.9E-157 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 SUPERFAMILY SSF56784 400 695 5.04E-63 T 11-10-2018 IPR036412 HAD-like superfamily UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 SUPERFAMILY SSF81665 149 692 2.75E-12 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00941 Cadmium-transporting ATPase signature 264 280 1.2E-14 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00941 Cadmium-transporting ATPase signature 19 40 1.2E-14 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00941 Cadmium-transporting ATPase signature 283 297 1.2E-14 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00941 Cadmium-transporting ATPase signature 183 203 1.2E-14 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00941 Cadmium-transporting ATPase signature 111 128 1.2E-14 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00941 Cadmium-transporting ATPase signature 8 17 1.2E-14 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 Gene3D G3DSA:3.40.50.1000 381 647 1.4E-82 T 11-10-2018 IPR023214 HAD superfamily UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 Pfam PF00403 Heavy-metal-associated domain 11 66 1.1E-12 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 ProSitePatterns PS01047 Heavy-metal-associated domain. 10 39 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 Gene3D G3DSA:3.30.70.100 7 87 1.3E-13 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 Pfam PF00702 haloacid dehalogenase-like hydrolase 396 608 7.5E-36 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 Pfam PF00122 E1-E2 ATPase 199 380 5.2E-46 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 149 697 5.0E-173 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 402 408 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 Gene3D G3DSA:2.70.150.20 186 302 1.3E-29 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 169 674 8.1E-72 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 Gene3D G3DSA:3.40.1110.10 411 523 1.4E-82 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 SUPERFAMILY SSF55008 4 72 1.83E-13 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 SUPERFAMILY SSF81653 201 298 2.62E-21 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 400 414 1.9E-25 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 630 1.9E-25 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 548 1.9E-25 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 248 262 1.9E-25 T 11-10-2018 UP12_15715 c5f75f9804834d87c1c1adb7f0e7d61b 699 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 594 613 1.9E-25 T 11-10-2018 UP12_03195 508998a4e76193896699a904ab1dc292 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 60 94 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UP12_03195 508998a4e76193896699a904ab1dc292 150 Gene3D G3DSA:1.10.10.10 2 145 4.7E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_03195 508998a4e76193896699a904ab1dc292 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 5.9E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03195 508998a4e76193896699a904ab1dc292 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 131 5.9E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03195 508998a4e76193896699a904ab1dc292 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 5.9E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03195 508998a4e76193896699a904ab1dc292 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 5.9E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03195 508998a4e76193896699a904ab1dc292 150 Pfam PF01047 MarR family 28 85 2.2E-13 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03195 508998a4e76193896699a904ab1dc292 150 SMART SM00347 21 121 1.8E-23 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_03195 508998a4e76193896699a904ab1dc292 150 SUPERFAMILY SSF46785 4 143 1.65E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_07005 219869fd49395b341c87481c26c71e23 92 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 3.0E-9 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_07005 219869fd49395b341c87481c26c71e23 92 SUPERFAMILY SSF89447 2 50 6.45E-14 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily UP12_07005 219869fd49395b341c87481c26c71e23 92 Gene3D G3DSA:2.10.260.10 1 51 2.0E-21 T 11-10-2018 UP12_07005 219869fd49395b341c87481c26c71e23 92 SMART SM00966 8 51 4.1E-7 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 UP12_17560 8ff67cfa76a2bb41024b1aa748c53e71 444 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 3 429 2.5E-47 T 11-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit UP12_16265 62a5575188c50542c81835bed21fc6b7 194 Gene3D G3DSA:3.30.230.40 90 194 2.4E-39 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 UP12_16265 62a5575188c50542c81835bed21fc6b7 194 SUPERFAMILY SSF54211 87 179 1.0E-34 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_16265 62a5575188c50542c81835bed21fc6b7 194 Gene3D G3DSA:3.30.230.40 1 89 1.2E-35 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 UP12_16265 62a5575188c50542c81835bed21fc6b7 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 8.2E-62 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UP12_16265 62a5575188c50542c81835bed21fc6b7 194 SUPERFAMILY SSF54211 2 86 3.04E-31 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_16265 62a5575188c50542c81835bed21fc6b7 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UP12_16265 62a5575188c50542c81835bed21fc6b7 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 41.274 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UP12_16265 62a5575188c50542c81835bed21fc6b7 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 UP12_05545 1077885282ca0c46fcc2ec452d2b67da 261 Pfam PF00326 Prolyl oligopeptidase family 98 256 8.2E-15 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 UP12_05545 1077885282ca0c46fcc2ec452d2b67da 261 SUPERFAMILY SSF53474 18 257 1.96E-35 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_05545 1077885282ca0c46fcc2ec452d2b67da 261 Gene3D G3DSA:3.40.50.1820 1 259 4.5E-53 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_10225 fb5cad9ce87347046937929323900aef 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 26 42 1.3E-39 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 UP12_10225 fb5cad9ce87347046937929323900aef 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 9 26 1.3E-39 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 UP12_10225 fb5cad9ce87347046937929323900aef 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 42 58 1.3E-39 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 UP12_10225 fb5cad9ce87347046937929323900aef 76 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 58 74 1.3E-39 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 UP12_10225 fb5cad9ce87347046937929323900aef 76 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 1 73 31.062 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 UP12_10225 fb5cad9ce87347046937929323900aef 76 Gene3D G3DSA:2.60.40.50 1 76 2.1E-42 T 11-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily UP12_10225 fb5cad9ce87347046937929323900aef 76 SUPERFAMILY SSF51219 7 74 4.97E-36 T 11-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily UP12_10225 fb5cad9ce87347046937929323900aef 76 Pfam PF02081 Tryptophan RNA-binding attenuator protein 6 73 2.9E-40 T 11-10-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 236 3.2E-31 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 Gene3D G3DSA:3.40.50.1000 3 263 6.1E-94 T 11-10-2018 IPR023214 HAD superfamily UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 263 2.0E-72 T 11-10-2018 UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 263 1.2E-72 T 11-10-2018 IPR000150 Cof family GO:0016787 UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 11-10-2018 UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 SUPERFAMILY SSF56784 1 268 2.07E-79 T 11-10-2018 IPR036412 HAD-like superfamily UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 11-10-2018 UP12_18430 172c42e703cfabeafb05a166321cc4ed 270 Gene3D G3DSA:3.30.1240.10 86 192 6.1E-94 T 11-10-2018 UP12_03495 ee661baec75f6097bf4a2c38da0721cd 513 Gene3D G3DSA:3.40.710.10 28 365 1.4E-84 T 11-10-2018 UP12_03495 ee661baec75f6097bf4a2c38da0721cd 513 SUPERFAMILY SSF56601 35 367 5.48E-70 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_03495 ee661baec75f6097bf4a2c38da0721cd 513 Pfam PF00144 Beta-lactamase 37 358 1.8E-62 T 11-10-2018 IPR001466 Beta-lactamase-related UP12_19345 9d7bd109fa6c8979191bc74f276dbf6b 529 Pfam PF14284 PcfJ-like protein 392 504 1.7E-11 T 11-10-2018 IPR025586 PcfJ-like protein UP12_14795 db5169c89128fa194daa394fc7a55be3 390 SUPERFAMILY SSF56796 1 388 4.32E-115 T 11-10-2018 UP12_14795 db5169c89128fa194daa394fc7a55be3 390 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 365 8.5E-100 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 UP12_14795 db5169c89128fa194daa394fc7a55be3 390 Gene3D G3DSA:3.40.50.1970 1 184 7.0E-55 T 11-10-2018 UP12_14795 db5169c89128fa194daa394fc7a55be3 390 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 UP12_14795 db5169c89128fa194daa394fc7a55be3 390 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 UP12_14795 db5169c89128fa194daa394fc7a55be3 390 Gene3D G3DSA:1.20.1090.10 185 389 8.3E-44 T 11-10-2018 UP12_17370 47c3473abf0161de13de6ab5ed06b7a7 96 Pfam PF09221 Bacteriocin class IId cyclical uberolysin-like 34 96 3.7E-18 T 11-10-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family UP12_17370 47c3473abf0161de13de6ab5ed06b7a7 96 Gene3D G3DSA:1.20.225.10 33 96 3.7E-20 T 11-10-2018 IPR009086 Bacteriocin AS-48 UP12_17370 47c3473abf0161de13de6ab5ed06b7a7 96 TIGRFAM TIGR03651 circ_ocin_uber: circular bacteriocin, circularin A/uberolysin family 32 96 4.1E-18 T 11-10-2018 IPR020038 Circular bacteriocin, circularin A/uberolysin family UP12_01330 b364c44fc8ac0de9cd0538cb02ef2645 152 Gene3D G3DSA:1.10.10.10 30 152 9.5E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01330 b364c44fc8ac0de9cd0538cb02ef2645 152 Pfam PF01047 MarR family 41 100 1.5E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01330 b364c44fc8ac0de9cd0538cb02ef2645 152 SMART SM00347 34 138 2.3E-18 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_01330 b364c44fc8ac0de9cd0538cb02ef2645 152 SUPERFAMILY SSF46785 40 150 2.11E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_15045 f2307d4fc0b3dd3e19619191d78d2c64 164 Pfam PF17355 Family of unknown function (DUF5383) 38 159 2.1E-35 T 11-10-2018 IPR020212 ESX secretion system protein YueC UP12_15045 f2307d4fc0b3dd3e19619191d78d2c64 164 TIGRFAM TIGR03927 T7SS_EssA_Firm: type VII secretion protein EssA 15 158 3.2E-39 T 11-10-2018 IPR018920 ESAT-6 secretion machinery protein EssA/YueC UP12_15045 f2307d4fc0b3dd3e19619191d78d2c64 164 ProDom PD090911 YUEC MEMBRANE TRANSMEMBRANE 17 132 3.0E-6 T 11-10-2018 IPR020212 ESX secretion system protein YueC UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 SUPERFAMILY SSF103473 6 461 2.18E-65 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 Pfam PF07690 Major Facilitator Superfamily 18 408 7.0E-54 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 107 127 6.6E-9 T 11-10-2018 UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 6.6E-9 T 11-10-2018 UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 301 325 6.6E-9 T 11-10-2018 UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 6.6E-9 T 11-10-2018 UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 Gene3D G3DSA:1.20.1250.20 261 472 7.4E-27 T 11-10-2018 UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 417 1.5E-109 T 11-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 UP12_02145 4e616c00d1e3058dd6b04c1bbba2e31b 477 Gene3D G3DSA:1.20.1720.10 14 256 4.9E-45 T 11-10-2018 UP12_10330 74fa763ce2c585668fd1aefbf25197bf 193 Gene3D G3DSA:3.30.70.1950 104 193 7.0E-31 T 11-10-2018 IPR038471 MecA, C-terminal domain superfamily UP12_10330 74fa763ce2c585668fd1aefbf25197bf 193 Hamap MF_01124 Adapter protein MecA [mecA]. 1 193 24.493 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA UP12_10330 74fa763ce2c585668fd1aefbf25197bf 193 Pfam PF05389 Negative regulator of genetic competence (MecA) 98 189 1.2E-15 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA UP12_10330 74fa763ce2c585668fd1aefbf25197bf 193 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 90 9.2E-26 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA UP12_10330 74fa763ce2c585668fd1aefbf25197bf 193 PIRSF PIRSF029008 1 193 5.9E-62 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA UP12_08025 718ffbc33bae4ef820a638edd270b0ba 166 SUPERFAMILY SSF64438 8 164 6.59E-45 T 11-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic UP12_08025 718ffbc33bae4ef820a638edd270b0ba 166 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 5 162 26.975 T 11-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 UP12_08025 718ffbc33bae4ef820a638edd270b0ba 166 Gene3D G3DSA:3.30.1330.200 7 165 5.9E-46 T 11-10-2018 IPR038592 CheD-like superfamily UP12_08025 718ffbc33bae4ef820a638edd270b0ba 166 Pfam PF03975 CheD chemotactic sensory transduction 52 158 2.0E-34 T 11-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 UP12_08890 aea334cb797858da4d7d636257028e63 216 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 6 111 3.0E-43 T 11-10-2018 IPR013559 YheO-like UP12_08890 aea334cb797858da4d7d636257028e63 216 Pfam PF13309 HTH domain 150 209 6.5E-21 T 11-10-2018 IPR039445 Transcriptional regulator DauR-like, HTH domain UP12_08890 aea334cb797858da4d7d636257028e63 216 Pfam PF08348 YheO-like PAS domain 8 120 9.5E-39 T 11-10-2018 IPR013559 YheO-like UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.3E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.3E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.5E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 246 1.8E-50 T 11-10-2018 UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 Gene3D G3DSA:3.40.50.720 1 251 8.9E-70 T 11-10-2018 UP12_13170 1e4953b8a513f4719d2f5a4bb8013326 251 SUPERFAMILY SSF51735 2 247 5.5E-65 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 SUPERFAMILY SSF53633 4 254 2.88E-68 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 SMART SM00359 277 355 5.3E-17 T 11-10-2018 IPR002478 PUA domain GO:0003723 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 PIRSF PIRSF000729 1 363 1.6E-135 T 11-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 360 3.3E-140 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 11-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 258 36.374 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 Gene3D G3DSA:2.30.130.10 266 361 7.0E-24 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 Gene3D G3DSA:3.40.1160.10 1 261 2.3E-84 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 1.1E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 1.1E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 1.1E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 1.1E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 1.1E-53 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 Pfam PF01472 PUA domain 277 346 4.0E-19 T 11-10-2018 IPR002478 PUA domain GO:0003723 UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 SUPERFAMILY SSF88697 277 360 3.15E-17 T 11-10-2018 IPR015947 PUA-like superfamily UP12_06375 fc41c2dff6e27c411807a87808e57dc5 365 Pfam PF00696 Amino acid kinase family 4 232 2.5E-45 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UP12_15325 7174d25da7189e043ee3595c4d0bde9f 435 Gene3D G3DSA:1.10.287.130 168 292 2.3E-13 T 11-10-2018 UP12_15325 7174d25da7189e043ee3595c4d0bde9f 435 SMART SM00388 230 297 2.4E-7 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_15325 7174d25da7189e043ee3595c4d0bde9f 435 SUPERFAMILY SSF47384 215 295 7.46E-10 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 UP12_15325 7174d25da7189e043ee3595c4d0bde9f 435 Gene3D G3DSA:3.30.565.10 304 430 8.1E-8 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_15325 7174d25da7189e043ee3595c4d0bde9f 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 290 1.2E-8 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 UP12_15325 7174d25da7189e043ee3595c4d0bde9f 435 Pfam PF14501 GHKL domain 347 426 9.4E-5 T 11-10-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain UP12_15325 7174d25da7189e043ee3595c4d0bde9f 435 SUPERFAMILY SSF55874 300 424 1.27E-8 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_13385 3a0dabf5155b167c7e8a4126e4b1eb1a 215 Gene3D G3DSA:3.40.50.1820 35 215 6.2E-51 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13385 3a0dabf5155b167c7e8a4126e4b1eb1a 215 SUPERFAMILY SSF53474 36 150 5.78E-23 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13385 3a0dabf5155b167c7e8a4126e4b1eb1a 215 Pfam PF01674 Lipase (class 2) 38 133 1.3E-13 T 11-10-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 UP12_10655 04056ef5d0099da6af3bb0115404d285 79 Pfam PF10827 Protein of unknown function (DUF2552) 2 79 7.0E-45 T 11-10-2018 IPR020157 Uncharacterised protein family YqkC UP12_10655 04056ef5d0099da6af3bb0115404d285 79 ProDom PD058987 CYTOSOLIC YQKC 21 79 8.0E-15 T 11-10-2018 IPR020157 Uncharacterised protein family YqkC UP12_16040 e1ecab3f2ba0f7d79b0a2dabae0a15ec 279 SUPERFAMILY SSF53448 4 226 1.22E-58 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_16040 e1ecab3f2ba0f7d79b0a2dabae0a15ec 279 Pfam PF00535 Glycosyl transferase family 2 7 159 3.7E-34 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_16040 e1ecab3f2ba0f7d79b0a2dabae0a15ec 279 Gene3D G3DSA:3.90.550.10 1 237 1.5E-61 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_14465 9924ea8036d2e32fc001707e64bc6e14 98 Gene3D G3DSA:1.10.260.40 11 93 4.2E-14 T 11-10-2018 UP12_14465 9924ea8036d2e32fc001707e64bc6e14 98 SUPERFAMILY SSF47413 15 70 3.94E-12 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_14465 9924ea8036d2e32fc001707e64bc6e14 98 Pfam PF12844 Helix-turn-helix domain 20 68 5.2E-11 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_14465 9924ea8036d2e32fc001707e64bc6e14 98 SMART SM00530 19 74 2.9E-5 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_12595 2f051d897d8e932512bb85f7c78040aa 1477 SUPERFAMILY SSF53955 1218 1309 9.6E-13 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily UP12_12595 2f051d897d8e932512bb85f7c78040aa 1477 Pfam PF01464 Transglycosylase SLT domain 1238 1342 8.1E-14 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 UP12_12595 2f051d897d8e932512bb85f7c78040aa 1477 Gene3D G3DSA:1.10.530.10 1215 1320 5.2E-8 T 11-10-2018 UP12_12595 2f051d897d8e932512bb85f7c78040aa 1477 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 168 511 1.3E-86 T 11-10-2018 IPR010090 Phage tail tape measure protein UP12_12595 2f051d897d8e932512bb85f7c78040aa 1477 Pfam PF10145 Phage-related minor tail protein 207 405 7.2E-51 T 11-10-2018 IPR010090 Phage tail tape measure protein UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.0E-20 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 SUPERFAMILY SSF46785 1 84 3.89E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 Pfam PF03466 LysR substrate binding domain 88 289 7.0E-38 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 Gene3D G3DSA:1.10.10.10 1 91 3.9E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 Gene3D G3DSA:3.40.190.290 92 297 6.1E-37 T 11-10-2018 UP12_06040 dcba0801072882b0190d70cafbe7ad62 298 SUPERFAMILY SSF53850 88 293 1.07E-39 T 11-10-2018 UP12_15070 87dc91095a54cf931c74af294eda33c7 97 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 5.1E-27 T 11-10-2018 IPR010310 Type VII secretion system ESAT-6-like UP12_15070 87dc91095a54cf931c74af294eda33c7 97 Pfam PF06013 Proteins of 100 residues with WXG 5 89 1.6E-25 T 11-10-2018 IPR010310 Type VII secretion system ESAT-6-like UP12_15070 87dc91095a54cf931c74af294eda33c7 97 SUPERFAMILY SSF140453 4 96 3.79E-23 T 11-10-2018 IPR036689 ESAT-6-like superfamily UP12_15070 87dc91095a54cf931c74af294eda33c7 97 Gene3D G3DSA:1.10.287.1060 1 97 5.8E-28 T 11-10-2018 UP12_05720 8f00e234f2d45d9f1284c0b7bf7c709a 192 Pfam PF13508 Acetyltransferase (GNAT) domain 52 110 9.8E-7 T 11-10-2018 IPR000182 GNAT domain UP12_05720 8f00e234f2d45d9f1284c0b7bf7c709a 192 SUPERFAMILY SSF55729 47 115 8.92E-8 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_05720 8f00e234f2d45d9f1284c0b7bf7c709a 192 Gene3D G3DSA:3.40.630.30 1 133 3.0E-23 T 11-10-2018 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 SUPERFAMILY SSF48256 2 371 1.16E-131 T 11-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 1.9E-126 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 Gene3D G3DSA:1.10.230.10 220 318 6.2E-125 T 11-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 7.0E-164 T 11-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 11-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 Gene3D G3DSA:1.10.580.10 24 343 6.2E-125 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 PIRSF PIRSF001369 1 372 2.1E-155 T 11-10-2018 IPR024176 Citrate synthase, bacterial-type UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 PRINTS PR00143 Citrate synthase signature 304 320 6.8E-41 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 PRINTS PR00143 Citrate synthase signature 123 136 6.8E-41 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 PRINTS PR00143 Citrate synthase signature 194 222 6.8E-41 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 PRINTS PR00143 Citrate synthase signature 324 338 6.8E-41 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 PRINTS PR00143 Citrate synthase signature 247 267 6.8E-41 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_13085 2946bdfca9bc1d3ae1909ef1fe22d289 372 PRINTS PR00143 Citrate synthase signature 172 187 6.8E-41 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 Pfam PF13229 Right handed beta helix region 317 445 1.9E-10 T 11-10-2018 IPR039448 Right handed beta helix domain UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SUPERFAMILY SSF51126 328 557 2.06E-15 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 Pfam PF12708 Pectate lyase superfamily protein 22 222 4.7E-13 T 11-10-2018 IPR024535 Pectate lyase superfamily protein UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SUPERFAMILY SSF51126 20 355 3.01E-33 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 328 349 450.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 471 493 3000.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 116 155 890.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 400 420 7300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 295 321 1800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 191 213 52.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 156 178 43.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 372 399 200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 214 236 1700.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 421 442 16.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 SMART SM00710 253 283 120.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 Gene3D G3DSA:2.160.20.10 22 315 2.8E-37 T 11-10-2018 IPR012334 Pectin lyase fold UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 Gene3D G3DSA:2.160.20.10 316 433 1.6E-7 T 11-10-2018 IPR012334 Pectin lyase fold UP12_02095 eed0ef6b6c70e96ccead8add2c48f87c 602 Gene3D G3DSA:2.160.20.10 456 588 9.8E-6 T 11-10-2018 IPR012334 Pectin lyase fold UP12_16615 d44521a43652312d634fc7beebcfdbde 351 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 93 246 7.0E-58 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_16615 d44521a43652312d634fc7beebcfdbde 351 Gene3D G3DSA:1.10.260.150 71 337 6.3E-102 T 11-10-2018 UP12_16615 d44521a43652312d634fc7beebcfdbde 351 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 94 246 6.8E-52 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 SUPERFAMILY SSF90123 6 342 7.19E-39 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 Gene3D G3DSA:3.40.50.300 328 573 3.9E-76 T 11-10-2018 UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 Pfam PF00664 ABC transporter transmembrane region 18 280 6.5E-14 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 6 531 2.6E-166 T 11-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 Pfam PF00005 ABC transporter 353 500 1.3E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 SUPERFAMILY SSF52540 333 570 2.19E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 SMART SM00382 362 554 2.4E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_18045 b427b28b50e7222a4ac1a400ae8c3e68 577 Gene3D G3DSA:1.20.1560.10 6 315 3.6E-25 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_02550 068e35411c21cbe3e0f14a9a89d72317 291 Pfam PF08678 Rsbr N terminal 11 138 4.2E-40 T 11-10-2018 IPR014792 RsbS co-antagonist protein RsbRA N-terminal domain UP12_02550 068e35411c21cbe3e0f14a9a89d72317 291 Pfam PF01740 STAS domain 158 256 5.1E-14 T 11-10-2018 IPR002645 STAS domain UP12_02550 068e35411c21cbe3e0f14a9a89d72317 291 SUPERFAMILY SSF52091 152 256 3.14E-16 T 11-10-2018 IPR036513 STAS domain superfamily UP12_02550 068e35411c21cbe3e0f14a9a89d72317 291 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 9 137 2.0E-26 T 11-10-2018 UP12_02550 068e35411c21cbe3e0f14a9a89d72317 291 Gene3D G3DSA:3.30.750.24 150 270 5.9E-39 T 11-10-2018 IPR036513 STAS domain superfamily UP12_02550 068e35411c21cbe3e0f14a9a89d72317 291 Gene3D G3DSA:1.10.490.10 1 138 2.7E-32 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UP12_05150 de9661b71fd49a5e21b0d154435e06a5 352 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 344 46.702 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UP12_05150 de9661b71fd49a5e21b0d154435e06a5 352 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 10 341 2.9E-128 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UP12_05150 de9661b71fd49a5e21b0d154435e06a5 352 Gene3D G3DSA:3.20.20.210 1 352 3.0E-149 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_05150 de9661b71fd49a5e21b0d154435e06a5 352 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UP12_05150 de9661b71fd49a5e21b0d154435e06a5 352 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 8 343 1.5E-122 T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UP12_05150 de9661b71fd49a5e21b0d154435e06a5 352 SUPERFAMILY SSF51726 6 346 3.14E-104 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_05150 de9661b71fd49a5e21b0d154435e06a5 352 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 UP12_14820 2edd308b54e23784c1e706e554e1b35d 166 Pfam PF01037 Lrp/AsnC ligand binding domain 73 145 2.1E-15 T 11-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain UP12_14820 2edd308b54e23784c1e706e554e1b35d 166 SUPERFAMILY SSF54909 66 147 2.68E-18 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_14820 2edd308b54e23784c1e706e554e1b35d 166 Gene3D G3DSA:1.10.10.10 3 53 1.4E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_14820 2edd308b54e23784c1e706e554e1b35d 166 SUPERFAMILY SSF46785 3 61 6.94E-7 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_14820 2edd308b54e23784c1e706e554e1b35d 166 SMART SM00344 3 114 2.1E-5 T 11-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 UP12_14820 2edd308b54e23784c1e706e554e1b35d 166 Gene3D G3DSA:3.30.70.920 55 153 2.3E-21 T 11-10-2018 UP12_15030 6d8bf271d34ea5dba553a511f28e2749 494 Pfam PF07819 PGAP1-like protein 110 154 9.4E-7 T 11-10-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 UP12_15030 6d8bf271d34ea5dba553a511f28e2749 494 Gene3D G3DSA:3.40.50.1820 46 270 3.6E-34 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_15030 6d8bf271d34ea5dba553a511f28e2749 494 SUPERFAMILY SSF53474 45 262 5.65E-28 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_18760 815f02147210d866cd94127300fc825e 223 Gene3D G3DSA:3.40.50.2300 1 123 2.3E-38 T 11-10-2018 UP12_18760 815f02147210d866cd94127300fc825e 223 Pfam PF00072 Response regulator receiver domain 3 111 8.1E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_18760 815f02147210d866cd94127300fc825e 223 SMART SM00448 1 111 4.1E-41 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_18760 815f02147210d866cd94127300fc825e 223 Gene3D G3DSA:1.10.10.10 124 223 8.1E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_18760 815f02147210d866cd94127300fc825e 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 219 1.6E-16 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_18760 815f02147210d866cd94127300fc825e 223 SUPERFAMILY SSF52172 1 165 1.08E-43 T 11-10-2018 IPR011006 CheY-like superfamily UP12_18760 815f02147210d866cd94127300fc825e 223 SMART SM00862 145 219 4.4E-13 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_12260 9cc1b5fe20dc6fe94a3e026c0185031d 263 SUPERFAMILY SSF51261 178 258 2.49E-9 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_12260 9cc1b5fe20dc6fe94a3e026c0185031d 263 Pfam PF01551 Peptidase family M23 166 256 3.0E-13 T 11-10-2018 IPR016047 Peptidase M23 UP12_12260 9cc1b5fe20dc6fe94a3e026c0185031d 263 Gene3D G3DSA:2.70.70.10 133 261 2.4E-14 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_12830 b63be731941d266c6fd6e75b73822c90 147 Pfam PF10702 Protein of unknown function (DUF2507) 19 140 1.6E-47 T 11-10-2018 IPR019642 Protein of unknown function DUF2507 UP12_12830 b63be731941d266c6fd6e75b73822c90 147 Gene3D G3DSA:3.30.1380.20 1 146 6.7E-58 T 11-10-2018 UP12_12830 b63be731941d266c6fd6e75b73822c90 147 SUPERFAMILY SSF111126 15 126 4.13E-22 T 11-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily UP12_18135 5679e7e33972f0f4fd0c2ab766a5c29d 141 Hamap MF_01512 Metallothiol transferase FosB [fosB]. 2 139 41.459 T 11-10-2018 IPR022858 Metallothiol transferase FosB GO:0016765|GO:0046677 UP12_18135 5679e7e33972f0f4fd0c2ab766a5c29d 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 1.2E-16 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_18135 5679e7e33972f0f4fd0c2ab766a5c29d 141 Gene3D G3DSA:3.10.180.10 1 136 1.4E-40 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_18135 5679e7e33972f0f4fd0c2ab766a5c29d 141 SUPERFAMILY SSF54593 3 130 2.28E-28 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_01660 95bddb3fadf8228fb394b2f270cb54e9 369 Pfam PF15608 PELOTA RNA binding domain 284 363 1.0E-32 T 11-10-2018 IPR028157 PELOTA RNA-binding domain UP12_01660 95bddb3fadf8228fb394b2f270cb54e9 369 Pfam PF11202 Phosphoribosyl transferase (PRTase) 9 258 2.2E-113 T 11-10-2018 IPR011215 Phosphoribosyl transferase UP12_01660 95bddb3fadf8228fb394b2f270cb54e9 369 PIRSF PIRSF020979 1 363 4.1E-92 T 11-10-2018 IPR011215 Phosphoribosyl transferase UP12_01170 a813c8ec750ac99aa002cc1229e8d215 375 Pfam PF04235 Protein of unknown function (DUF418) 225 375 1.6E-39 T 11-10-2018 IPR007349 Domain of unknown function DUF418 UP12_04820 6242e41fc8f426062598bb411c7aea4a 294 SUPERFAMILY SSF55729 18 252 7.6E-37 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_04820 6242e41fc8f426062598bb411c7aea4a 294 Pfam PF13527 Acetyltransferase (GNAT) domain 19 130 1.3E-13 T 11-10-2018 UP12_04820 6242e41fc8f426062598bb411c7aea4a 294 Gene3D G3DSA:3.40.630.30 1 177 8.1E-31 T 11-10-2018 UP12_18315 6918fb4f4d4ea3c72134a5358d3405d2 199 PIRSF PIRSF037394 1 190 2.2E-64 T 11-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted UP12_18315 6918fb4f4d4ea3c72134a5358d3405d2 199 Pfam PF09819 ABC-type cobalt transport system, permease component 6 124 8.9E-38 T 11-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted UP12_05880 fb5246d9973f6545d63a7ace9b043c39 116 Pfam PF07098 Protein of unknown function (DUF1360) 9 110 4.8E-38 T 11-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 UP12_06795 7605efd98ea0d03b626fdd8a92ab2d21 425 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 9 377 7.6E-106 T 11-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 UP12_06795 7605efd98ea0d03b626fdd8a92ab2d21 425 Gene3D G3DSA:1.20.1250.20 1 186 9.3E-18 T 11-10-2018 UP12_06795 7605efd98ea0d03b626fdd8a92ab2d21 425 Pfam PF07690 Major Facilitator Superfamily 12 356 5.4E-25 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_06795 7605efd98ea0d03b626fdd8a92ab2d21 425 SUPERFAMILY SSF103473 5 407 1.19E-39 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_06795 7605efd98ea0d03b626fdd8a92ab2d21 425 Gene3D G3DSA:1.20.1250.20 219 413 4.7E-15 T 11-10-2018 UP12_11290 77c2b255ef3ccadc95838580c8af7832 260 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 14 260 8.0E-120 T 11-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 UP12_11290 77c2b255ef3ccadc95838580c8af7832 260 Pfam PF00005 ABC transporter 29 185 1.0E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_11290 77c2b255ef3ccadc95838580c8af7832 260 SMART SM00382 38 231 2.7E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_11290 77c2b255ef3ccadc95838580c8af7832 260 SUPERFAMILY SSF52540 12 255 6.19E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11290 77c2b255ef3ccadc95838580c8af7832 260 Gene3D G3DSA:3.40.50.300 11 258 4.4E-59 T 11-10-2018 UP12_11290 77c2b255ef3ccadc95838580c8af7832 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_17525 bdd7799f8bb9fec95ebfad733bc02b6c 282 Pfam PF03099 Biotin/lipoate A/B protein ligase family 74 184 3.0E-16 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UP12_17525 bdd7799f8bb9fec95ebfad733bc02b6c 282 SUPERFAMILY SSF55681 7 274 1.57E-67 T 11-10-2018 UP12_17525 bdd7799f8bb9fec95ebfad733bc02b6c 282 Gene3D G3DSA:3.30.930.10 6 282 2.2E-79 T 11-10-2018 UP12_17525 bdd7799f8bb9fec95ebfad733bc02b6c 282 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 7 282 48.094 T 11-10-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 MetaCyc: PWY-6987 UP12_01130 6e5402edd2b52387a35d73e432c5e655 305 Pfam PF00005 ABC transporter 19 162 1.4E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_01130 6e5402edd2b52387a35d73e432c5e655 305 Gene3D G3DSA:3.40.50.300 2 235 5.3E-62 T 11-10-2018 UP12_01130 6e5402edd2b52387a35d73e432c5e655 305 SMART SM00382 28 210 1.3E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_01130 6e5402edd2b52387a35d73e432c5e655 305 SUPERFAMILY SSF52540 3 226 1.28E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_01130 6e5402edd2b52387a35d73e432c5e655 305 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16290 141dfedbcbb261820d836e804cee846f 212 Gene3D G3DSA:3.40.30.10 10 202 5.6E-45 T 11-10-2018 UP12_16290 141dfedbcbb261820d836e804cee846f 212 Pfam PF01323 DSBA-like thioredoxin domain 11 204 1.9E-11 T 11-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 UP12_16290 141dfedbcbb261820d836e804cee846f 212 Gene3D G3DSA:1.10.472.60 45 173 5.6E-45 T 11-10-2018 UP12_16290 141dfedbcbb261820d836e804cee846f 212 SUPERFAMILY SSF52833 6 209 9.6E-28 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_16795 bcbdb611018a22550b0809697271a25c 326 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 UP12_16795 bcbdb611018a22550b0809697271a25c 326 SUPERFAMILY SSF53613 4 300 9.82E-83 T 11-10-2018 IPR029056 Ribokinase-like UP12_16795 bcbdb611018a22550b0809697271a25c 326 Pfam PF00294 pfkB family carbohydrate kinase 5 292 8.7E-66 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB UP12_16795 bcbdb611018a22550b0809697271a25c 326 Gene3D G3DSA:3.40.1190.20 1 305 3.7E-89 T 11-10-2018 IPR029056 Ribokinase-like UP12_03795 1649581e8708ea2b0b87b61a367eecdd 141 Gene3D G3DSA:1.10.1660.10 1 140 2.5E-27 T 11-10-2018 UP12_03795 1649581e8708ea2b0b87b61a367eecdd 141 SUPERFAMILY SSF46955 4 120 3.43E-22 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily UP12_03795 1649581e8708ea2b0b87b61a367eecdd 141 SMART SM00422 4 74 1.9E-29 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_03795 1649581e8708ea2b0b87b61a367eecdd 141 Pfam PF13411 MerR HTH family regulatory protein 4 71 3.0E-19 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_03795 1649581e8708ea2b0b87b61a367eecdd 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 7.9E-6 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_03795 1649581e8708ea2b0b87b61a367eecdd 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 7.9E-6 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_03795 1649581e8708ea2b0b87b61a367eecdd 141 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 7.9E-6 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 UP12_11595 472f813e4e0d4677240f8bb4890b4def 371 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 11 371 4.0E-169 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 UP12_11595 472f813e4e0d4677240f8bb4890b4def 371 PIRSF PIRSF019549 4 371 1.7E-182 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 UP12_11595 472f813e4e0d4677240f8bb4890b4def 371 Pfam PF03418 Germination protease 18 370 2.3E-191 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 UP12_11595 472f813e4e0d4677240f8bb4890b4def 371 Hamap MF_00626 Germination protease [gpr]. 1 371 162.223 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 UP12_11595 472f813e4e0d4677240f8bb4890b4def 371 TIGRFAM TIGR01441 GPR: GPR endopeptidase 11 371 1.3E-189 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 UP12_11595 472f813e4e0d4677240f8bb4890b4def 371 SUPERFAMILY SSF53163 5 370 1.31E-129 T 11-10-2018 IPR023430 Peptidase HybD-like domain superfamily UP12_10150 004a2a223e491a8a8e595bff95f3416b 365 Pfam PF00155 Aminotransferase class I and II 30 354 8.7E-64 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_10150 004a2a223e491a8a8e595bff95f3416b 365 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 360 61.711 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UP12_10150 004a2a223e491a8a8e595bff95f3416b 365 Gene3D G3DSA:3.40.640.10 43 268 9.4E-118 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_10150 004a2a223e491a8a8e595bff95f3416b 365 Gene3D G3DSA:3.90.1150.10 20 350 9.4E-118 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_10150 004a2a223e491a8a8e595bff95f3416b 365 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 357 2.6E-115 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 UP12_10150 004a2a223e491a8a8e595bff95f3416b 365 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 220 229 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 UP12_10150 004a2a223e491a8a8e595bff95f3416b 365 SUPERFAMILY SSF53383 4 361 8.9E-83 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_10485 c1002ca5b54c05d6a8c043e219af52e0 77 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 4 75 1.9E-25 T 11-10-2018 IPR018680 Protein of unknown function DUF2164 UP12_06275 fff917431fff4231ef8141f0ae9db39f 274 Gene3D G3DSA:3.40.50.10780 1 208 2.1E-78 T 11-10-2018 IPR027476 D-aminopeptidase, N-terminal UP12_06275 fff917431fff4231ef8141f0ae9db39f 274 Pfam PF04951 D-aminopeptidase 1 262 1.2E-96 T 11-10-2018 IPR007035 Peptidase M55, D-aminopeptidase UP12_06275 fff917431fff4231ef8141f0ae9db39f 274 Gene3D G3DSA:3.30.1360.130 209 274 7.4E-28 T 11-10-2018 UP12_06275 fff917431fff4231ef8141f0ae9db39f 274 SUPERFAMILY SSF63992 1 274 6.8E-104 T 11-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily UP12_06275 fff917431fff4231ef8141f0ae9db39f 274 PIRSF PIRSF015853 1 271 5.5E-108 T 11-10-2018 IPR007035 Peptidase M55, D-aminopeptidase UP12_14875 a4aa635d7d7e0145d1ee8c9fca42d9e7 185 Pfam PF17328 Family of unknown function (DUF5366) 29 184 1.7E-61 T 11-10-2018 IPR035289 Protein of unknown function DUF5366 UP12_14875 a4aa635d7d7e0145d1ee8c9fca42d9e7 185 ProDom PD108804 YUFK TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL 1 184 3.0E-42 T 11-10-2018 IPR035289 Protein of unknown function DUF5366 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 Pfam PF00722 Glycosyl hydrolases family 16 56 238 3.2E-45 T 11-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 ProSitePatterns PS01034 Glycosyl hydrolases family 16 active sites. 134 144 - T 11-10-2018 IPR008263 Glycoside hydrolase, family 16, active site GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 185 202 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 131 146 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 229 241 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 205 227 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 147 160 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 91 109 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 110 126 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 PRINTS PR00737 Glycosyl hydrolase family 16 signature 165 182 9.5E-80 T 11-10-2018 IPR008264 Beta-glucanase GO:0004553|GO:0005975 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 SUPERFAMILY SSF49899 34 242 6.1E-60 T 11-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily UP12_02870 6be46bbcc915c494736796329cd84f0b 243 Gene3D G3DSA:2.60.120.200 25 112 3.2E-20 T 11-10-2018 UP12_02870 6be46bbcc915c494736796329cd84f0b 243 Gene3D G3DSA:2.60.120.200 114 243 4.7E-51 T 11-10-2018 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 SUPERFAMILY SSF54966 3 113 1.83E-26 T 11-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 164 172 - T 11-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 2 96 1.5E-7 T 11-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 2 402 58.852 T 11-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 Gene3D G3DSA:3.30.70.150 1 115 4.9E-27 T 11-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 SUPERFAMILY SSF51649 117 404 1.44E-85 T 11-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 321 401 8.0E-17 T 11-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 122 291 4.7E-24 T 11-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 Gene3D G3DSA:3.20.20.110 117 405 7.2E-103 T 11-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 UP12_06570 11a3a7b8fd01ca995fe017b633cac0c7 406 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 402 3.2E-209 T 11-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 UP12_07615 63331b14c11634211bf59b37a84cf783 569 Gene3D G3DSA:1.10.8.50 168 237 1.5E-25 T 11-10-2018 UP12_07615 63331b14c11634211bf59b37a84cf783 569 Gene3D G3DSA:3.40.970.40 241 289 2.5E-21 T 11-10-2018 UP12_07615 63331b14c11634211bf59b37a84cf783 569 Pfam PF05670 Domain of unknown function (DUF814) 454 538 2.0E-30 T 11-10-2018 IPR008532 Domain of unknown function DUF814 UP12_07615 63331b14c11634211bf59b37a84cf783 569 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 2.7E-171 T 11-10-2018 UP12_07615 63331b14c11634211bf59b37a84cf783 569 Gene3D G3DSA:2.30.310.10 1 167 3.0E-69 T 11-10-2018 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 Gene3D G3DSA:3.40.50.1380 1 196 1.2E-89 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 4 512 4.6E-249 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 Pfam PF02142 MGS-like domain 16 129 7.0E-30 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 446 1.3E-120 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 Gene3D G3DSA:3.40.140.20 203 359 1.3E-59 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 SMART SM00851 15 130 1.1E-55 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 512 44.958 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 SUPERFAMILY SSF52335 3 194 1.83E-71 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 Gene3D G3DSA:3.40.140.20 387 512 1.3E-56 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 SMART SM00798 135 447 1.3E-196 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 SUPERFAMILY SSF53927 207 512 3.71E-128 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_03385 dfb9ce67c34363348b5c6cc04386b580 512 PIRSF PIRSF000414 1 512 1.2E-213 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 UP12_07805 e2faabb71daf6d8d2772641a89a0d3ba 244 SUPERFAMILY SSF75217 1 235 1.24E-101 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases UP12_07805 e2faabb71daf6d8d2772641a89a0d3ba 244 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 244 113.493 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UP12_07805 e2faabb71daf6d8d2772641a89a0d3ba 244 Gene3D G3DSA:3.40.1280.10 1 172 5.6E-73 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal UP12_07805 e2faabb71daf6d8d2772641a89a0d3ba 244 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 235 1.1E-107 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UP12_07805 e2faabb71daf6d8d2772641a89a0d3ba 244 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 1.5E-76 T 11-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UP12_07805 e2faabb71daf6d8d2772641a89a0d3ba 244 Gene3D G3DSA:1.10.1270.20 173 244 5.3E-32 T 11-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UP12_07805 e2faabb71daf6d8d2772641a89a0d3ba 244 PIRSF PIRSF000386 1 243 2.6E-105 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 UP12_06095 8567022032d8928e0a3a633fcc332328 370 Gene3D G3DSA:3.90.180.10 8 359 3.5E-128 T 11-10-2018 UP12_06095 8567022032d8928e0a3a633fcc332328 370 SUPERFAMILY SSF50129 2 191 2.13E-52 T 11-10-2018 IPR011032 GroES-like superfamily UP12_06095 8567022032d8928e0a3a633fcc332328 370 SMART SM00829 12 362 4.3E-4 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_06095 8567022032d8928e0a3a633fcc332328 370 SUPERFAMILY SSF51735 160 330 1.36E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06095 8567022032d8928e0a3a633fcc332328 370 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UP12_06095 8567022032d8928e0a3a633fcc332328 370 Gene3D G3DSA:3.40.50.720 172 308 3.5E-128 T 11-10-2018 UP12_06095 8567022032d8928e0a3a633fcc332328 370 Pfam PF00107 Zinc-binding dehydrogenase 195 322 1.5E-26 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_06095 8567022032d8928e0a3a633fcc332328 370 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 153 3.2E-22 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 147 1.8E-40 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 Gene3D G3DSA:1.20.58.1830 3 31 4.3E-60 T 11-10-2018 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 Gene3D G3DSA:1.20.1330.10 43 191 4.3E-60 T 11-10-2018 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 Pfam PF00700 Bacterial flagellin C-terminal helical region 214 298 2.3E-32 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 Gene3D G3DSA:1.10.8.410 246 299 5.8E-29 T 11-10-2018 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 PRINTS PR00207 Flagellin signature 35 52 1.1E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 PRINTS PR00207 Flagellin signature 74 93 1.1E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 PRINTS PR00207 Flagellin signature 110 133 1.1E-17 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 UP12_06125 077755663e639abd4b91a08e7c26fa84 299 SUPERFAMILY SSF64518 1 299 1.31E-89 T 11-10-2018 UP12_15935 6706f636993471fac8e5878626ecb2b9 345 Gene3D G3DSA:1.10.10.10 18 89 2.5E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15935 6706f636993471fac8e5878626ecb2b9 345 Gene3D G3DSA:3.40.50.1360 90 340 4.0E-88 T 11-10-2018 UP12_15935 6706f636993471fac8e5878626ecb2b9 345 SUPERFAMILY SSF100950 90 337 3.02E-68 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_15935 6706f636993471fac8e5878626ecb2b9 345 Pfam PF04198 Putative sugar-binding domain 92 337 4.1E-73 T 11-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 UP12_15935 6706f636993471fac8e5878626ecb2b9 345 SUPERFAMILY SSF46785 19 82 9.45E-12 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_04270 3bf948033ec10ee5f1e7bd73b9f66494 418 Pfam PF01381 Helix-turn-helix 9 58 1.1E-9 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_04270 3bf948033ec10ee5f1e7bd73b9f66494 418 SUPERFAMILY SSF48452 181 318 1.14E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_04270 3bf948033ec10ee5f1e7bd73b9f66494 418 Gene3D G3DSA:1.25.40.10 166 407 7.1E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_04270 3bf948033ec10ee5f1e7bd73b9f66494 418 SUPERFAMILY SSF47413 3 62 2.73E-14 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_04270 3bf948033ec10ee5f1e7bd73b9f66494 418 Gene3D G3DSA:1.10.260.40 2 66 9.7E-14 T 11-10-2018 UP12_04270 3bf948033ec10ee5f1e7bd73b9f66494 418 SMART SM00530 8 62 4.1E-8 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 211 6.8E-28 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 Pfam PF08281 Sigma-70, region 4 164 207 1.6E-10 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 PIRSF PIRSF002939 3 218 4.0E-111 T 11-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 62 75 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 SUPERFAMILY SSF88659 125 212 2.22E-11 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 16 212 9.3E-112 T 11-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 SUPERFAMILY SSF88946 19 107 7.2E-22 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 UP12_00640 ea1e1313638adcffacf05ebf6b099f82 218 Pfam PF04542 Sigma-70 region 2 38 107 2.0E-14 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 UP12_15865 c7e78c33b4c28384beab78d37cfeb0e4 178 PIRSF PIRSF006707 2 178 2.2E-48 T 11-10-2018 IPR026282 DNA-binding protein, MJ1563 type UP12_15865 c7e78c33b4c28384beab78d37cfeb0e4 178 SUPERFAMILY SSF46785 9 160 1.78E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_15865 c7e78c33b4c28384beab78d37cfeb0e4 178 Gene3D G3DSA:1.10.10.10 8 91 1.1E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_17085 dcde1986be410a28d67d7f9e990be2bc 599 Pfam PF00005 ABC transporter 365 519 4.2E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17085 dcde1986be410a28d67d7f9e990be2bc 599 SUPERFAMILY SSF90123 12 317 1.2E-33 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_17085 dcde1986be410a28d67d7f9e990be2bc 599 Gene3D G3DSA:1.20.1560.10 10 323 4.7E-23 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_17085 dcde1986be410a28d67d7f9e990be2bc 599 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_17085 dcde1986be410a28d67d7f9e990be2bc 599 SMART SM00382 373 565 1.8E-18 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17085 dcde1986be410a28d67d7f9e990be2bc 599 SUPERFAMILY SSF52540 343 589 1.22E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17085 dcde1986be410a28d67d7f9e990be2bc 599 Gene3D G3DSA:3.40.50.300 340 598 6.3E-73 T 11-10-2018 UP12_14910 7a38add3614c2309aceb9c1e12e96427 445 Pfam PF03390 2-hydroxycarboxylate transporter family 29 439 2.8E-160 T 11-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 UP12_14910 7a38add3614c2309aceb9c1e12e96427 445 TIGRFAM TIGR00783 ccs: citrate carrier protein, CCS family 23 440 2.0E-167 T 11-10-2018 IPR018025 2-hydroxycarboxylate transporter, Proteobacteria/Firmicutes UP12_14910 7a38add3614c2309aceb9c1e12e96427 445 PIRSF PIRSF005348 9 445 5.0E-170 T 11-10-2018 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 UP12_00065 6ff53b7506fb6e1872a03a5b9f4bbc3d 319 Pfam PF14175 YaaC-like Protein 9 308 1.9E-108 T 11-10-2018 IPR026988 YaaC-like protein UP12_11040 b6d4311bc770999a680a7a505405562d 171 PIRSF PIRSF021435 1 171 2.7E-64 T 11-10-2018 IPR014198 Stage III sporulation protein AB UP12_11040 b6d4311bc770999a680a7a505405562d 171 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 3 171 4.1E-53 T 11-10-2018 IPR014198 Stage III sporulation protein AB UP12_11040 b6d4311bc770999a680a7a505405562d 171 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 3 171 1.2E-65 T 11-10-2018 IPR014198 Stage III sporulation protein AB UP12_15680 d71862fa4939ad6b5573234838c9f90d 221 SUPERFAMILY SSF161098 6 218 6.67E-50 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15680 d71862fa4939ad6b5573234838c9f90d 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 216 1.5E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_15680 d71862fa4939ad6b5573234838c9f90d 221 Gene3D G3DSA:1.10.3720.10 3 221 1.3E-55 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15680 d71862fa4939ad6b5573234838c9f90d 221 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 13 217 1.9E-70 T 11-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 UP12_18895 6f3c723df333be172492772e14cf9aa3 235 SUPERFAMILY SSF46894 129 230 9.07E-32 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_18895 6f3c723df333be172492772e14cf9aa3 235 Pfam PF00072 Response regulator receiver domain 5 114 2.2E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_18895 6f3c723df333be172492772e14cf9aa3 235 SMART SM00448 3 113 2.1E-48 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_18895 6f3c723df333be172492772e14cf9aa3 235 SMART SM00862 153 229 5.1E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_18895 6f3c723df333be172492772e14cf9aa3 235 SUPERFAMILY SSF52172 2 127 1.22E-44 T 11-10-2018 IPR011006 CheY-like superfamily UP12_18895 6f3c723df333be172492772e14cf9aa3 235 Gene3D G3DSA:3.40.50.2300 1 131 4.1E-41 T 11-10-2018 UP12_18895 6f3c723df333be172492772e14cf9aa3 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 229 9.4E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_18895 6f3c723df333be172492772e14cf9aa3 235 Gene3D G3DSA:1.10.10.10 132 235 3.4E-42 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_17495 9359cd2694e94cb3103561823c2a25ce 433 Gene3D G3DSA:1.20.1250.30 235 412 6.5E-166 T 11-10-2018 UP12_17495 9359cd2694e94cb3103561823c2a25ce 433 Pfam PF01966 HD domain 61 181 1.6E-17 T 11-10-2018 IPR006674 HD domain UP12_17495 9359cd2694e94cb3103561823c2a25ce 433 Gene3D G3DSA:1.10.3210.10 11 401 6.5E-166 T 11-10-2018 UP12_17495 9359cd2694e94cb3103561823c2a25ce 433 SUPERFAMILY SSF109604 6 413 7.12E-120 T 11-10-2018 UP12_17495 9359cd2694e94cb3103561823c2a25ce 433 SMART SM00471 57 187 1.5E-13 T 11-10-2018 IPR003607 HD/PDEase domain UP12_12880 afe6a68f0f173daecefa39b4c2ab8b36 151 Pfam PF15599 Immunity protein 63 54 145 4.0E-28 T 11-10-2018 IPR028952 Immunity protein 63 UP12_11010 0cd8b6823b6f796b02fd48c539671078 210 Gene3D G3DSA:3.30.300.270 94 209 2.4E-39 T 11-10-2018 IPR038503 Stage III sporulation protein AH-like superfamily UP12_11010 0cd8b6823b6f796b02fd48c539671078 210 Pfam PF12685 SpoIIIAH-like protein 5 201 2.1E-43 T 11-10-2018 IPR024232 Stage III sporulation protein AH-like UP12_16955 390df557cea676e0bc7bf04b5c7708b7 535 Pfam PF04434 SWIM zinc finger 76 98 2.7E-5 T 11-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 UP12_16560 5726da383ef7a70671bbf3bba47bef3d 506 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 440 499 6.4E-12 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain UP12_16560 5726da383ef7a70671bbf3bba47bef3d 506 Pfam PF00460 Flagella basal body rod protein 8 37 2.6E-6 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 UP12_16560 5726da383ef7a70671bbf3bba47bef3d 506 SUPERFAMILY SSF64518 138 499 1.7E-18 T 11-10-2018 UP12_16560 5726da383ef7a70671bbf3bba47bef3d 506 PRINTS PR01005 Flagellar hook-associated protein signature 467 491 2.1E-5 T 11-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 UP12_16560 5726da383ef7a70671bbf3bba47bef3d 506 PRINTS PR01005 Flagellar hook-associated protein signature 14 37 2.1E-5 T 11-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 UP12_16560 5726da383ef7a70671bbf3bba47bef3d 506 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 499 1.4E-105 T 11-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 UP12_16560 5726da383ef7a70671bbf3bba47bef3d 506 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site UP12_17360 9a27fea1d9ddbc5772c5c69b26f57c03 176 Pfam PF01944 Stage II sporulation protein M 18 161 4.4E-10 T 11-10-2018 IPR002798 Stage II sporulation protein M-like UP12_04435 e8b456a048b3482ea49ad80797dec9fc 145 SUPERFAMILY SSF46785 8 137 9.33E-42 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_04435 e8b456a048b3482ea49ad80797dec9fc 145 Gene3D G3DSA:3.30.1490.190 88 145 4.7E-25 T 11-10-2018 UP12_04435 e8b456a048b3482ea49ad80797dec9fc 145 Gene3D G3DSA:1.10.10.10 1 87 1.4E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04435 e8b456a048b3482ea49ad80797dec9fc 145 Pfam PF01475 Ferric uptake regulator family 15 133 1.5E-40 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 UP12_05835 c93c06ac182458f54819e2ddd445123a 337 Pfam PF00899 ThiF family 5 239 2.1E-55 T 11-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UP12_05835 c93c06ac182458f54819e2ddd445123a 337 SUPERFAMILY SSF69572 3 325 1.07E-79 T 11-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 UP12_05835 c93c06ac182458f54819e2ddd445123a 337 Gene3D G3DSA:3.40.50.720 2 248 1.4E-71 T 11-10-2018 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 SUPERFAMILY SSF53732 11 642 1.57E-223 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 SUPERFAMILY SSF52016 646 905 1.37E-86 T 11-10-2018 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 Gene3D G3DSA:1.10.1440.20 606 667 2.7E-23 T 11-10-2018 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 24 906 0.0 T 11-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 ProSitePatterns PS00450 Aconitase family signature 1. 442 458 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 ProSitePatterns PS01244 Aconitase family signature 2. 508 521 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 Gene3D G3DSA:3.30.499.10 381 605 8.3E-100 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 Pfam PF00330 Aconitase family (aconitate hydratase) 81 577 1.7E-174 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 Gene3D G3DSA:3.30.499.20 12 380 2.6E-159 T 11-10-2018 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 Pfam PF00694 Aconitase C-terminal domain 707 834 6.7E-45 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 508 521 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 300 313 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 380 394 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 286 299 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 210 223 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 446 457 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 153 166 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 177 185 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 PRINTS PR00415 Aconitase family signature 224 239 1.1E-40 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 UP12_08750 a78fd6fccb387f3a9b937a1ad9bc5db0 909 Gene3D G3DSA:3.20.19.10 669 906 6.7E-103 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 UP12_11705 478686558a2a78ffc330766d669276d6 138 Pfam PF14430 Immunity protein Imm1 81 126 1.4E-5 T 11-10-2018 IPR025680 Immunity protein Imm1 UP12_02175 c7dfbcd18dacbb1dd4bcaa75cc05483f 462 Pfam PF13520 Amino acid permease 12 435 1.6E-42 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_02175 c7dfbcd18dacbb1dd4bcaa75cc05483f 462 PIRSF PIRSF006060 1 461 1.2E-82 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_02175 c7dfbcd18dacbb1dd4bcaa75cc05483f 462 Gene3D G3DSA:1.20.1740.10 4 461 1.8E-69 T 11-10-2018 UP12_15005 0bafdda64efc3fa076c7b44948e84736 82 ProDom PD060056 YUEH 1 82 7.0E-18 T 11-10-2018 IPR020260 Uncharacterised protein family YueH UP12_15005 0bafdda64efc3fa076c7b44948e84736 82 Pfam PF14166 YueH-like protein 2 81 3.1E-33 T 11-10-2018 IPR020260 Uncharacterised protein family YueH UP12_02660 ae0a657ea9309ceaeb35667137f14d27 373 Gene3D G3DSA:1.10.150.130 59 160 9.1E-15 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal UP12_02660 ae0a657ea9309ceaeb35667137f14d27 373 Pfam PF14657 Arm DNA-binding domain 9 52 4.1E-8 T 11-10-2018 IPR028259 AP2-like integrase, N-terminal domain UP12_02660 ae0a657ea9309ceaeb35667137f14d27 373 SUPERFAMILY SSF56349 62 367 4.12E-56 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 UP12_02660 ae0a657ea9309ceaeb35667137f14d27 373 Gene3D G3DSA:1.10.443.10 161 373 4.3E-41 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 UP12_02660 ae0a657ea9309ceaeb35667137f14d27 373 Pfam PF00589 Phage integrase family 173 358 2.5E-19 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 UP12_02660 ae0a657ea9309ceaeb35667137f14d27 373 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 62 117 2.7E-7 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 8.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 8.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 8.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 8.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 8.9E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.8E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.8E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.8E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 246 3.0E-58 T 11-10-2018 UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 Gene3D G3DSA:3.40.50.720 1 253 6.9E-80 T 11-10-2018 UP12_06810 91d9cefd9cfb892a089c6388bce26d84 254 SUPERFAMILY SSF51735 4 249 2.72E-80 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13685 07c7257680c9c2eeaa7c39e3a1b61377 331 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 154 168 5.0E-39 T 11-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD UP12_13685 07c7257680c9c2eeaa7c39e3a1b61377 331 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 267 286 5.0E-39 T 11-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD UP12_13685 07c7257680c9c2eeaa7c39e3a1b61377 331 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 94 108 5.0E-39 T 11-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD UP12_13685 07c7257680c9c2eeaa7c39e3a1b61377 331 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 247 261 5.0E-39 T 11-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD UP12_13685 07c7257680c9c2eeaa7c39e3a1b61377 331 PRINTS PR02026 YtrC/YtrD probable ABC transporter permease signature 171 183 5.0E-39 T 11-10-2018 IPR023264 ABC transporter, acetoin utilisation, predicted permease Ytrc/YtrD UP12_12785 e34fddb9db51b5e514bee851f4f1a4ac 70 SUPERFAMILY SSF46894 8 52 2.48E-15 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_12785 e34fddb9db51b5e514bee851f4f1a4ac 70 Gene3D G3DSA:1.10.10.10 1 57 5.2E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_12785 e34fddb9db51b5e514bee851f4f1a4ac 70 SMART SM00421 9 61 1.4E-8 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_12785 e34fddb9db51b5e514bee851f4f1a4ac 70 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 12 26 1.3E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_12785 e34fddb9db51b5e514bee851f4f1a4ac 70 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 42 54 1.3E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_12785 e34fddb9db51b5e514bee851f4f1a4ac 70 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 26 42 1.3E-9 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_12785 e34fddb9db51b5e514bee851f4f1a4ac 70 Pfam PF00196 Bacterial regulatory proteins, luxR family 12 51 7.8E-17 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 UP12_13620 bb4bcf10bfade0800a7283df2504d1e7 123 Pfam PF01638 HxlR-like helix-turn-helix 16 104 5.3E-40 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_13620 bb4bcf10bfade0800a7283df2504d1e7 123 SUPERFAMILY SSF46785 3 110 1.42E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_13620 bb4bcf10bfade0800a7283df2504d1e7 123 Gene3D G3DSA:1.10.10.10 2 108 1.6E-38 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_04180 3ae8797ebb38e2472f15e844dc44ef56 182 Pfam PF04892 VanZ like family 46 173 1.3E-26 T 11-10-2018 IPR006976 VanZ-like UP12_04670 ed9eafbac2249c3dc228281ed9541d99 387 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 9 380 2.0E-184 T 11-10-2018 IPR014230 Sporulation protein YhbH UP12_04670 ed9eafbac2249c3dc228281ed9541d99 387 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 7 385 31.426 T 11-10-2018 IPR006698 Uncharacterised protein family UPF0229 UP12_04670 ed9eafbac2249c3dc228281ed9541d99 387 Pfam PF04285 Protein of unknown function (DUF444) 195 383 7.1E-69 T 11-10-2018 IPR006698 Uncharacterised protein family UPF0229 UP12_04670 ed9eafbac2249c3dc228281ed9541d99 387 Pfam PF04285 Protein of unknown function (DUF444) 13 186 8.7E-35 T 11-10-2018 IPR006698 Uncharacterised protein family UPF0229 UP12_12455 4dd261b7e6f910dd74a901db556e4c24 78 SUPERFAMILY SSF47336 2 76 2.22E-14 T 11-10-2018 IPR036736 ACP-like superfamily UP12_12455 4dd261b7e6f910dd74a901db556e4c24 78 Hamap MF_00565 D-alanyl carrier protein [dltC]. 1 78 45.497 T 11-10-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 UP12_12455 4dd261b7e6f910dd74a901db556e4c24 78 Gene3D G3DSA:1.10.1200.10 1 78 4.5E-24 T 11-10-2018 IPR036736 ACP-like superfamily UP12_12455 4dd261b7e6f910dd74a901db556e4c24 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 5.1E-9 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_12455 4dd261b7e6f910dd74a901db556e4c24 78 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 76 1.6E-35 T 11-10-2018 IPR003230 D-alanyl carrier protein GO:0019350|GO:0036370 UP12_08900 361f7d11c30916031e86bf89ad8e2685 389 Gene3D G3DSA:3.50.50.60 6 381 6.3E-112 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_08900 361f7d11c30916031e86bf89ad8e2685 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 5.7E-22 T 11-10-2018 UP12_08900 361f7d11c30916031e86bf89ad8e2685 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 5.7E-22 T 11-10-2018 UP12_08900 361f7d11c30916031e86bf89ad8e2685 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 5.7E-22 T 11-10-2018 UP12_08900 361f7d11c30916031e86bf89ad8e2685 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 5.7E-22 T 11-10-2018 UP12_08900 361f7d11c30916031e86bf89ad8e2685 389 SUPERFAMILY SSF51905 9 375 2.51E-44 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_08900 361f7d11c30916031e86bf89ad8e2685 389 Pfam PF01494 FAD binding domain 10 332 2.9E-21 T 11-10-2018 IPR002938 FAD-binding domain GO:0071949 UP12_12990 31fba4d7d1c65a0d03b403d115f5e1ce 259 Gene3D G3DSA:3.40.50.1000 2 254 1.1E-52 T 11-10-2018 IPR023214 HAD superfamily UP12_12990 31fba4d7d1c65a0d03b403d115f5e1ce 259 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 109 231 2.2E-10 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UP12_12990 31fba4d7d1c65a0d03b403d115f5e1ce 259 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 231 7.5E-25 T 11-10-2018 UP12_12990 31fba4d7d1c65a0d03b403d115f5e1ce 259 Gene3D G3DSA:1.20.120.710 14 130 1.1E-52 T 11-10-2018 UP12_12990 31fba4d7d1c65a0d03b403d115f5e1ce 259 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 225 3.2E-15 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UP12_12990 31fba4d7d1c65a0d03b403d115f5e1ce 259 SUPERFAMILY SSF56784 1 258 5.65E-44 T 11-10-2018 IPR036412 HAD-like superfamily UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 Pfam PF02803 Thiolase, C-terminal domain 269 389 1.2E-48 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 PIRSF PIRSF000429 1 391 2.9E-128 T 11-10-2018 IPR002155 Thiolase GO:0016747 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 SUPERFAMILY SSF53901 1 264 9.61E-73 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 Pfam PF00108 Thiolase, N-terminal domain 5 260 1.9E-75 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 5.9E-139 T 11-10-2018 IPR002155 Thiolase GO:0016747 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 Gene3D G3DSA:3.40.47.10 5 274 3.3E-147 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 Gene3D G3DSA:3.40.47.10 131 387 3.3E-147 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 SUPERFAMILY SSF53901 269 390 2.3E-42 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_15455 1af05a01da0fc51ee00a3ffcfffe42cf 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 58 79 2.3E-8 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 134 150 2.3E-8 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 262 281 2.3E-8 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 103 116 2.3E-8 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 159 173 2.3E-8 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 SUPERFAMILY SSF53850 34 355 4.15E-72 T 11-10-2018 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 Gene3D G3DSA:3.40.190.10 144 353 3.8E-83 T 11-10-2018 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 Gene3D G3DSA:3.40.190.10 51 324 3.8E-83 T 11-10-2018 UP12_01980 928f16cb3ffeb4cbaed1d25ce9862637 361 Pfam PF13416 Bacterial extracellular solute-binding protein 53 315 1.9E-40 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein UP12_05480 73f40e5e8b95d936781ee03bcb458f60 285 Gene3D G3DSA:3.40.630.90 148 285 5.0E-7 T 11-10-2018 UP12_05480 73f40e5e8b95d936781ee03bcb458f60 285 SUPERFAMILY SSF55729 7 265 1.95E-31 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_05480 73f40e5e8b95d936781ee03bcb458f60 285 Gene3D G3DSA:3.40.630.30 7 123 1.1E-15 T 11-10-2018 UP12_05480 73f40e5e8b95d936781ee03bcb458f60 285 Pfam PF13673 Acetyltransferase (GNAT) domain 30 121 1.4E-9 T 11-10-2018 IPR000182 GNAT domain UP12_05475 fb3a8ea8fd8a74a9f031385fb91c0208 604 Pfam PF04183 IucA / IucC family 145 393 1.4E-71 T 11-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 UP12_05475 fb3a8ea8fd8a74a9f031385fb91c0208 604 Gene3D G3DSA:1.10.510.40 383 576 5.9E-58 T 11-10-2018 UP12_05475 fb3a8ea8fd8a74a9f031385fb91c0208 604 Pfam PF06276 Ferric iron reductase FhuF-like transporter 416 576 1.5E-44 T 11-10-2018 IPR022770 Ferric iron reductase FhuF domain UP12_05475 fb3a8ea8fd8a74a9f031385fb91c0208 604 Gene3D G3DSA:1.10.274.90 2 133 1.9E-21 T 11-10-2018 UP12_00110 9b263a8a0efd5dcf7bd24ec277ec07d8 219 SUPERFAMILY SSF52540 11 212 3.8E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00110 9b263a8a0efd5dcf7bd24ec277ec07d8 219 PIRSF PIRSF000705 1 218 5.8E-65 T 11-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 UP12_00110 9b263a8a0efd5dcf7bd24ec277ec07d8 219 Pfam PF01712 Deoxynucleoside kinase 12 211 7.2E-65 T 11-10-2018 IPR031314 Deoxynucleoside kinase domain UP12_00110 9b263a8a0efd5dcf7bd24ec277ec07d8 219 Gene3D G3DSA:3.40.50.300 9 214 6.0E-53 T 11-10-2018 UP12_13570 4f61d579f051f001b07c5aaf5b16cc1c 510 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 45 489 4.4E-179 T 11-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 UP12_13570 4f61d579f051f001b07c5aaf5b16cc1c 510 ProSitePatterns PS01303 BCCT family of transporters signature. 310 319 - T 11-10-2018 IPR018093 BCCT transporter, conserved site UP12_13570 4f61d579f051f001b07c5aaf5b16cc1c 510 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 488 9.7E-197 T 11-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 UP12_12645 5bd2699f390935b1d60f85570bceb1b3 426 Pfam PF04860 Phage portal protein 51 375 3.3E-94 T 11-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein UP12_12645 5bd2699f390935b1d60f85570bceb1b3 426 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 43 381 2.8E-91 T 11-10-2018 IPR006427 Phage portal protein, HK97 UP12_09675 d870ae64b56aea02d4f95f407488264e 431 Pfam PF00535 Glycosyl transferase family 2 6 166 4.8E-22 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_09675 d870ae64b56aea02d4f95f407488264e 431 Gene3D G3DSA:3.90.550.10 4 242 1.3E-57 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_09675 d870ae64b56aea02d4f95f407488264e 431 SUPERFAMILY SSF53448 4 211 3.0E-36 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_07625 71e26222a3008894a22508ea091b413e 291 Pfam PF08340 Domain of unknown function (DUF1732) 207 291 2.3E-37 T 11-10-2018 IPR013551 Domain of unknown function DUF1732 UP12_07625 71e26222a3008894a22508ea091b413e 291 Pfam PF03755 YicC-like family, N-terminal region 2 156 8.8E-38 T 11-10-2018 IPR013527 YicC-like, N-terminal UP12_07625 71e26222a3008894a22508ea091b413e 291 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 291 2.3E-108 T 11-10-2018 IPR005229 Conserved hypothetical protein CHP00255 UP12_08780 6bc244adaa4de5067ecdfb117d1255e6 95 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 87 3.5E-7 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 UP12_08780 6bc244adaa4de5067ecdfb117d1255e6 95 PIRSF PIRSF034852 1 95 7.8E-39 T 11-10-2018 IPR008326 Uncharacterised conserved protein UCP034852 UP12_08780 6bc244adaa4de5067ecdfb117d1255e6 95 SUPERFAMILY SSF89360 3 93 4.84E-14 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UP12_08780 6bc244adaa4de5067ecdfb117d1255e6 95 Gene3D G3DSA:2.60.300.12 1 95 2.1E-5 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UP12_15250 92137af25c9a047e4e402fd53b52f72b 101 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 1.9E-24 T 11-10-2018 IPR014931 Protein of unknown function DUF1805 UP12_15250 92137af25c9a047e4e402fd53b52f72b 101 SUPERFAMILY SSF102891 2 99 2.75E-34 T 11-10-2018 IPR036493 Hypothetical protein YunC superfamily UP12_15250 92137af25c9a047e4e402fd53b52f72b 101 Gene3D G3DSA:3.30.1980.10 1 100 1.3E-23 T 11-10-2018 IPR036493 Hypothetical protein YunC superfamily UP12_18865 4926f6db95fdd97b435c18dd0126ec31 155 Pfam PF00583 Acetyltransferase (GNAT) family 47 143 2.1E-16 T 11-10-2018 IPR000182 GNAT domain UP12_18865 4926f6db95fdd97b435c18dd0126ec31 155 SUPERFAMILY SSF55729 2 149 4.12E-27 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_18865 4926f6db95fdd97b435c18dd0126ec31 155 Gene3D G3DSA:3.40.630.30 1 154 1.2E-42 T 11-10-2018 UP12_13205 bb9374651be75c3525813ffdbe98da53 166 Hamap MF_00269 Thiol peroxidase [tpx]. 3 163 37.381 T 11-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 UP12_13205 bb9374651be75c3525813ffdbe98da53 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 11-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 UP12_13205 bb9374651be75c3525813ffdbe98da53 166 SUPERFAMILY SSF52833 3 160 2.2E-43 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_13205 bb9374651be75c3525813ffdbe98da53 166 Gene3D G3DSA:3.40.30.10 2 164 5.9E-48 T 11-10-2018 UP12_13205 bb9374651be75c3525813ffdbe98da53 166 Pfam PF00578 AhpC/TSA family 20 142 1.4E-20 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_18195 cfc06041559c83e25d08b03f4c998534 468 TIGRFAM TIGR00931 antiport_nhaC: Na+/H+ antiporter NhaC 5 458 6.8E-203 T 11-10-2018 IPR004770 Na+/H+ antiporter NhaC GO:0015297|GO:0016021 UP12_18195 cfc06041559c83e25d08b03f4c998534 468 Pfam PF03553 Na+/H+ antiporter family 159 451 4.6E-68 T 11-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 UP12_04375 f4d7e912291318b117ae7a63d0a63ba2 54 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 7 54 2.0E-13 T 11-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 UP12_04375 f4d7e912291318b117ae7a63d0a63ba2 54 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 6 54 1.3E-15 T 11-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 UP12_11685 879637607dc5ac7ab3a669cce8a552b6 246 Gene3D G3DSA:3.20.20.370 29 243 2.0E-69 T 11-10-2018 UP12_11685 879637607dc5ac7ab3a669cce8a552b6 246 Pfam PF01522 Polysaccharide deacetylase 43 163 1.4E-28 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_11685 879637607dc5ac7ab3a669cce8a552b6 246 SUPERFAMILY SSF88713 25 235 4.45E-61 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_09000 e9cc697db081c7f1ce8aad5fffc53e04 276 Gene3D G3DSA:1.10.3720.10 3 263 3.4E-59 T 11-10-2018 IPR035906 MetI-like superfamily UP12_09000 e9cc697db081c7f1ce8aad5fffc53e04 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 268 3.4E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_09000 e9cc697db081c7f1ce8aad5fffc53e04 276 SUPERFAMILY SSF161098 8 276 2.15E-67 T 11-10-2018 IPR035906 MetI-like superfamily UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 Gene3D G3DSA:1.10.3210.10 201 376 4.1E-25 T 11-10-2018 UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 Pfam PF08668 HDOD domain 209 337 3.4E-18 T 11-10-2018 IPR013976 Metal-dependent hydrolase HDOD UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 SMART SM00052 1 201 1.7E-4 T 11-10-2018 IPR001633 EAL domain UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 Gene3D G3DSA:3.20.20.450 2 200 5.0E-20 T 11-10-2018 IPR035919 EAL domain superfamily UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 PIRSF PIRSF003180 1 408 7.4E-142 T 11-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 SUPERFAMILY SSF141868 3 199 5.36E-30 T 11-10-2018 IPR035919 EAL domain superfamily UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 SUPERFAMILY SSF109604 187 405 3.45E-40 T 11-10-2018 UP12_14985 e5dc9be96100cf7dabf6f5415fa5a9ae 408 Pfam PF00563 EAL domain 47 196 3.6E-15 T 11-10-2018 IPR001633 EAL domain UP12_10920 2408c793dbdc8ebbeb26f1f76e76a08d 78 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 5.0E-18 T 11-10-2018 IPR020138 Uncharacterised protein family YqzF UP12_10920 2408c793dbdc8ebbeb26f1f76e76a08d 78 Pfam PF11118 Protein of unknown function (DUF2627) 3 76 3.1E-32 T 11-10-2018 IPR020138 Uncharacterised protein family YqzF UP12_05765 c64136927f8c4c24d1a4dc81852568ba 132 Gene3D G3DSA:1.10.490.10 1 132 6.6E-54 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UP12_05765 c64136927f8c4c24d1a4dc81852568ba 132 SUPERFAMILY SSF46458 9 124 8.28E-38 T 11-10-2018 IPR009050 Globin-like superfamily UP12_05765 c64136927f8c4c24d1a4dc81852568ba 132 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 52 76 - T 11-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 UP12_05765 c64136927f8c4c24d1a4dc81852568ba 132 Pfam PF01152 Bacterial-like globin 9 121 2.1E-30 T 11-10-2018 IPR001486 Truncated hemoglobin GO:0019825 UP12_09975 05b2def813fb24d24c178761b74c70a4 139 Pfam PF00011 Hsp20/alpha crystallin family 65 138 7.2E-5 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain UP12_09975 05b2def813fb24d24c178761b74c70a4 139 SUPERFAMILY SSF49764 46 137 1.92E-9 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_09975 05b2def813fb24d24c178761b74c70a4 139 Gene3D G3DSA:2.60.40.790 30 139 3.7E-12 T 11-10-2018 IPR008978 HSP20-like chaperone UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 PIRSF PIRSF004803 1 555 1.8E-220 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 SUPERFAMILY SSF56281 10 424 2.62E-76 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 Pfam PF00753 Metallo-beta-lactamase superfamily 20 167 1.1E-8 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 Gene3D G3DSA:3.60.15.10 12 442 6.8E-161 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 43.805 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 Gene3D G3DSA:3.40.50.10710 208 358 6.8E-161 T 11-10-2018 UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 362 407 5.9E-9 T 11-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 SMART SM00849 21 220 2.2E-13 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 9 553 1.9E-211 T 11-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 UP12_08210 36279752ec934aae1b7e44bbc9fd86ed 555 Gene3D G3DSA:3.10.20.580 449 555 1.2E-37 T 11-10-2018 UP12_07270 2e11d004a684f96eafb76419bf4db95f 90 PIRSF PIRSF031653 1 90 2.2E-34 T 11-10-2018 IPR016979 Protein of unknown function DUF2129 UP12_07270 2e11d004a684f96eafb76419bf4db95f 90 Hamap MF_01126 UPF0298 protein . 1 78 22.168 T 11-10-2018 IPR016979 Protein of unknown function DUF2129 UP12_07270 2e11d004a684f96eafb76419bf4db95f 90 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 6.4E-32 T 11-10-2018 IPR016979 Protein of unknown function DUF2129 UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 98 108 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 Pfam PF00082 Subtilase family 56 269 7.0E-39 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 Gene3D G3DSA:3.40.50.200 22 288 7.2E-70 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 PRINTS PR00723 Subtilisin serine protease family (S8) signature 56 75 6.7E-17 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 PRINTS PR00723 Subtilisin serine protease family (S8) signature 94 107 6.7E-17 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 PRINTS PR00723 Subtilisin serine protease family (S8) signature 247 263 6.7E-17 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 61 72 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site UP12_18400 c81f4af00df961902f37aad3bf42e18f 290 SUPERFAMILY SSF52743 50 269 1.31E-66 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_12210 88d419986153c98cf12045992c19f3ff 383 PIRSF PIRSF005572 2 383 9.0E-119 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 UP12_12210 88d419986153c98cf12045992c19f3ff 383 Gene3D G3DSA:3.40.640.10 62 236 3.2E-117 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_12210 88d419986153c98cf12045992c19f3ff 383 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 194 213 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UP12_12210 88d419986153c98cf12045992c19f3ff 383 Pfam PF00266 Aminotransferase class-V 5 369 5.5E-75 T 11-10-2018 IPR000192 Aminotransferase class V domain UP12_12210 88d419986153c98cf12045992c19f3ff 383 Gene3D G3DSA:3.90.1150.10 5 372 3.2E-117 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_12210 88d419986153c98cf12045992c19f3ff 383 SUPERFAMILY SSF53383 4 377 1.21E-87 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_12210 88d419986153c98cf12045992c19f3ff 383 Gene3D G3DSA:1.10.260.50 16 280 3.2E-117 T 11-10-2018 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Gene3D G3DSA:3.40.50.740 78 478 6.6E-154 T 11-10-2018 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Gene3D G3DSA:2.40.40.20 545 680 1.2E-24 T 11-10-2018 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 SMART SM00926 9 64 8.7E-17 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Gene3D G3DSA:3.40.228.10 145 543 6.6E-154 T 11-10-2018 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Gene3D G3DSA:3.30.2070.10 433 521 6.6E-154 T 11-10-2018 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Gene3D G3DSA:2.20.25.90 5 69 7.6E-15 T 11-10-2018 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Pfam PF00384 Molybdopterin oxidoreductase 67 473 4.8E-61 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 418 435 - T 11-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Pfam PF01568 Molydopterin dinucleotide binding domain 565 669 5.5E-16 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 SUPERFAMILY SSF50692 527 678 2.19E-26 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 12 63 1.4E-15 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 UP12_09350 22b30610c6e0a498503e2f8dd2f1a08e 680 SUPERFAMILY SSF53706 12 563 3.27E-165 T 11-10-2018 UP12_10400 4e8d5cbd0d132814f40a926328761efc 240 SMART SM00862 158 235 1.3E-25 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_10400 4e8d5cbd0d132814f40a926328761efc 240 Gene3D G3DSA:3.40.50.2300 1 128 5.6E-42 T 11-10-2018 UP12_10400 4e8d5cbd0d132814f40a926328761efc 240 SUPERFAMILY SSF52172 6 193 4.98E-44 T 11-10-2018 IPR011006 CheY-like superfamily UP12_10400 4e8d5cbd0d132814f40a926328761efc 240 Pfam PF00072 Response regulator receiver domain 9 117 2.0E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_10400 4e8d5cbd0d132814f40a926328761efc 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 235 5.1E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_10400 4e8d5cbd0d132814f40a926328761efc 240 SMART SM00448 7 117 2.9E-47 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_10400 4e8d5cbd0d132814f40a926328761efc 240 Gene3D G3DSA:1.10.10.10 129 238 3.9E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.1E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.1E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.1E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.1E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 8.0E-9 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 Gene3D G3DSA:1.20.5.1150 16 56 1.7E-18 T 11-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 Pfam PF01165 Ribosomal protein S21 5 57 2.5E-21 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 2.4E-21 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.664 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11530 14b9659fd5d60c2bb9b0636536514cb6 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 11-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_12235 be3be28ce7d563e45a863b6d2db04ea6 194 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 14 71 1.1E-21 T 11-10-2018 IPR039506 SpoOB, alpha-helical domain UP12_12235 be3be28ce7d563e45a863b6d2db04ea6 194 SMART SM01317 73 187 8.7E-64 T 11-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal UP12_12235 be3be28ce7d563e45a863b6d2db04ea6 194 Gene3D G3DSA:1.10.287.130 1 71 1.6E-27 T 11-10-2018 UP12_12235 be3be28ce7d563e45a863b6d2db04ea6 194 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 74 185 8.6E-38 T 11-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal UP12_12235 be3be28ce7d563e45a863b6d2db04ea6 194 Gene3D G3DSA:3.30.565.30 72 190 1.6E-36 T 11-10-2018 IPR037100 Sporulation initiation phosphotransferase B, C-terminal domain superfamily UP12_12235 be3be28ce7d563e45a863b6d2db04ea6 194 SUPERFAMILY SSF55890 15 190 3.79E-55 T 11-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 UP12_11820 c35a629e6135b4d616b9bb78c51d518e 286 Gene3D G3DSA:3.40.190.10 45 262 3.1E-45 T 11-10-2018 UP12_11820 c35a629e6135b4d616b9bb78c51d518e 286 Gene3D G3DSA:3.40.190.10 105 226 3.1E-45 T 11-10-2018 UP12_11820 c35a629e6135b4d616b9bb78c51d518e 286 SUPERFAMILY SSF53850 33 267 2.17E-35 T 11-10-2018 UP12_11820 c35a629e6135b4d616b9bb78c51d518e 286 SMART SM00062 35 264 2.1E-13 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_11820 c35a629e6135b4d616b9bb78c51d518e 286 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 262 4.0E-32 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_13705 8dd4df7f755650f0bb3d9b932c24b966 91 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 3.3E-36 T 11-10-2018 IPR019668 Uncharacterised protein family YtzC UP12_07400 a831589fa1cdee3cb6379e71dec85eb5 241 Gene3D G3DSA:3.30.70.1880 85 240 5.3E-14 T 11-10-2018 UP12_07400 a831589fa1cdee3cb6379e71dec85eb5 241 Pfam PF05949 Bacterial protein of unknown function (DUF881) 86 229 2.5E-27 T 11-10-2018 IPR010273 Protein of unknown function DUF881 UP12_00690 30dd4ce807a562f258a4078078956306 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 80 5.1E-16 T 11-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 UP12_00690 30dd4ce807a562f258a4078078956306 82 SUPERFAMILY SSF55315 5 81 4.24E-19 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_00690 30dd4ce807a562f258a4078078956306 82 Hamap MF_00574 Putative ribosomal protein L7Ae-like. 2 82 23.836 T 11-10-2018 IPR023460 Ribosomal protein L7Ae, putative UP12_00690 30dd4ce807a562f258a4078078956306 82 PRINTS PR00884 Ribosomal protein HS6 signature 20 30 1.3E-5 T 11-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00690 30dd4ce807a562f258a4078078956306 82 PRINTS PR00884 Ribosomal protein HS6 signature 30 41 1.3E-5 T 11-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00690 30dd4ce807a562f258a4078078956306 82 PRINTS PR00884 Ribosomal protein HS6 signature 56 66 1.3E-5 T 11-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00690 30dd4ce807a562f258a4078078956306 82 PRINTS PR00884 Ribosomal protein HS6 signature 70 82 1.3E-5 T 11-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00690 30dd4ce807a562f258a4078078956306 82 Gene3D G3DSA:3.30.1330.30 1 82 9.2E-24 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_12460 de0f6471672b8ebf91dd4132851a3b21 394 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 3 390 1.0E-158 T 11-10-2018 IPR024024 D-alanyl transfer protein DltB UP12_12460 de0f6471672b8ebf91dd4132851a3b21 394 PIRSF PIRSF016636 2 393 1.6E-88 T 11-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB UP12_12460 de0f6471672b8ebf91dd4132851a3b21 394 PIRSF PIRSF500216 1 394 8.6E-164 T 11-10-2018 IPR024024 D-alanyl transfer protein DltB UP12_12460 de0f6471672b8ebf91dd4132851a3b21 394 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 51 379 1.3E-15 T 11-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT UP12_16470 6714f9a5f4fd89b37c7cb723ec5162dc 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 2.2E-89 T 11-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 UP12_16470 6714f9a5f4fd89b37c7cb723ec5162dc 228 Gene3D G3DSA:3.40.50.300 1 224 1.1E-66 T 11-10-2018 UP12_16470 6714f9a5f4fd89b37c7cb723ec5162dc 228 Pfam PF00005 ABC transporter 19 165 1.3E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16470 6714f9a5f4fd89b37c7cb723ec5162dc 228 SMART SM00382 27 221 4.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16470 6714f9a5f4fd89b37c7cb723ec5162dc 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16470 6714f9a5f4fd89b37c7cb723ec5162dc 228 SUPERFAMILY SSF52540 1 221 3.64E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03955 91becc978c93c71acc25957792fc4a8b 478 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 3 464 1.8E-170 T 11-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 7 465 2.6E-212 T 11-10-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 SUPERFAMILY SSF55604 8 83 1.02E-21 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 111 1.5E-22 T 11-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 Gene3D G3DSA:3.30.1360.60 1 79 6.0E-30 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 165 452 5.6E-91 T 11-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 Pfam PF02378 Phosphotransferase system, EIIC 112 409 3.0E-45 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_03955 91becc978c93c71acc25957792fc4a8b 478 Pfam PF00367 phosphotransferase system, EIIB 10 42 1.4E-15 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 SUPERFAMILY SSF81901 4 208 3.92E-37 T 11-10-2018 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 90 160 1.1E-6 T 11-10-2018 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 Pfam PF00515 Tetratricopeptide repeat 170 203 2.3E-8 T 11-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 SMART SM00028 102 135 0.0028 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 SMART SM00028 170 203 9.6E-7 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 SMART SM00028 68 101 0.061 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 SMART SM00028 34 67 0.03 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 SMART SM00028 3 33 6.4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 SMART SM00028 136 169 7.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 Pfam PF14559 Tetratricopeptide repeat 11 69 7.8E-7 T 11-10-2018 UP12_12030 9e11218b8959e83f12832eadfbdf0bbb 217 Gene3D G3DSA:1.25.40.10 27 217 1.0E-52 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_10670 8c0cd11b92ac6ef2c1d46e645998843b 323 Gene3D G3DSA:3.40.630.30 6 145 3.9E-19 T 11-10-2018 UP12_10670 8c0cd11b92ac6ef2c1d46e645998843b 323 Gene3D G3DSA:3.30.460.10 147 316 8.4E-59 T 11-10-2018 UP12_10670 8c0cd11b92ac6ef2c1d46e645998843b 323 Pfam PF13673 Acetyltransferase (GNAT) domain 22 146 9.1E-16 T 11-10-2018 IPR000182 GNAT domain UP12_10670 8c0cd11b92ac6ef2c1d46e645998843b 323 Pfam PF04229 GrpB protein 150 309 1.1E-53 T 11-10-2018 IPR007344 GrpB/Dephospho-CoA kinase UP12_10670 8c0cd11b92ac6ef2c1d46e645998843b 323 SUPERFAMILY SSF81301 153 314 1.54E-53 T 11-10-2018 UP12_10670 8c0cd11b92ac6ef2c1d46e645998843b 323 SUPERFAMILY SSF55729 15 136 3.49E-19 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_15745 a453eea4d9c4fd0d725f3bfd18f3647c 310 Gene3D G3DSA:3.40.50.12740 1 165 4.1E-22 T 11-10-2018 UP12_15745 a453eea4d9c4fd0d725f3bfd18f3647c 310 Pfam PF08664 YcbB domain 159 299 2.2E-47 T 11-10-2018 IPR013972 YcbB domain UP12_15745 a453eea4d9c4fd0d725f3bfd18f3647c 310 Pfam PF00072 Response regulator receiver domain 4 112 4.9E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_15745 a453eea4d9c4fd0d725f3bfd18f3647c 310 SUPERFAMILY SSF52172 2 139 6.83E-23 T 11-10-2018 IPR011006 CheY-like superfamily UP12_15745 a453eea4d9c4fd0d725f3bfd18f3647c 310 SMART SM00448 1 114 1.9E-16 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_09020 c002762b770747ae7fd319ce081e7133 231 SUPERFAMILY SSF51366 3 217 3.04E-49 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_09020 c002762b770747ae7fd319ce081e7133 231 Gene3D G3DSA:3.20.20.70 5 230 2.8E-69 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_09020 c002762b770747ae7fd319ce081e7133 231 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 199 7.1E-56 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 UP12_01990 6d93a84685ba128ae6bbdb5a15e4d0f4 289 Gene3D G3DSA:1.10.3720.10 10 286 1.1E-56 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01990 6d93a84685ba128ae6bbdb5a15e4d0f4 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 283 7.9E-12 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_01990 6d93a84685ba128ae6bbdb5a15e4d0f4 289 SUPERFAMILY SSF161098 6 284 1.68E-54 T 11-10-2018 IPR035906 MetI-like superfamily UP12_10170 1d5769f628c53c383fd7120ffd4d23a8 250 Pfam PF00218 Indole-3-glycerol phosphate synthase 9 247 2.9E-88 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 UP12_10170 1d5769f628c53c383fd7120ffd4d23a8 250 Gene3D G3DSA:3.20.20.70 1 250 2.9E-89 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_10170 1d5769f628c53c383fd7120ffd4d23a8 250 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 249 32.362 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 UP12_10170 1d5769f628c53c383fd7120ffd4d23a8 250 SUPERFAMILY SSF51366 9 249 1.88E-80 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_10170 1d5769f628c53c383fd7120ffd4d23a8 250 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 42 60 - T 11-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 UP12_12700 bdddd43d4b22c6fd6dc37d91dae8d270 149 Gene3D G3DSA:1.20.140.160 9 141 5.4E-6 T 11-10-2018 UP12_12700 bdddd43d4b22c6fd6dc37d91dae8d270 149 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 8 144 4.8E-44 T 11-10-2018 IPR006524 Transcription activator, ArpU family UP12_12700 bdddd43d4b22c6fd6dc37d91dae8d270 149 SUPERFAMILY SSF88659 73 143 8.18E-6 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 SUPERFAMILY SSF53901 3 236 8.02E-48 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 Pfam PF02803 Thiolase, C-terminal domain 239 358 1.6E-23 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 SUPERFAMILY SSF53901 239 358 2.27E-24 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 Gene3D G3DSA:3.40.47.10 118 357 4.7E-100 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 358 1.3E-88 T 11-10-2018 IPR002155 Thiolase GO:0016747 UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 Gene3D G3DSA:3.40.47.10 4 243 4.7E-100 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 PIRSF PIRSF000429 1 362 1.9E-86 T 11-10-2018 IPR002155 Thiolase GO:0016747 UP12_11955 f79aa2376a67d52fe4225b1db53821a6 365 Pfam PF00108 Thiolase, N-terminal domain 4 229 2.0E-42 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 UP12_00370 6ce53e125329d3b9a0e6006422a0a1be 212 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 1.3E-42 T 11-10-2018 IPR014242 Spore cortex biosynthesis protein, YabQ UP12_00370 6ce53e125329d3b9a0e6006422a0a1be 212 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 4.1E-21 T 11-10-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like UP12_08550 1f0441377d4a0ed6c7240184766cfeaf 193 Gene3D G3DSA:1.20.144.10 72 182 1.5E-20 T 11-10-2018 UP12_08550 1f0441377d4a0ed6c7240184766cfeaf 193 SMART SM00014 57 164 1.2E-17 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UP12_08550 1f0441377d4a0ed6c7240184766cfeaf 193 Pfam PF01569 PAP2 superfamily 58 166 2.7E-18 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase UP12_08550 1f0441377d4a0ed6c7240184766cfeaf 193 SUPERFAMILY SSF48317 2 175 1.96E-33 T 11-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily UP12_10525 5836b51364381a8aa766ad000e63fa0f 116 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 3 116 6.5E-53 T 11-10-2018 IPR014204 Sporulation stage V, protein AE UP12_10525 5836b51364381a8aa766ad000e63fa0f 116 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 2 111 1.7E-39 T 11-10-2018 IPR005562 SpoVA UP12_10350 0788bc83fd2c03c1e5fbb4752fcbd1f0 213 Pfam PF02517 CAAX protease self-immunity 100 181 1.8E-8 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 UP12_14740 3462a043d8852d09a192ac26eaf5bcde 246 ProDom PD119415 TRANSGLUTAMINASE TRANSFERASE ACYLTRANSFERASE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE TGASE SPORULATION TGL 1 237 1.0E-74 T 11-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 UP12_14740 3462a043d8852d09a192ac26eaf5bcde 246 Hamap MF_00727 Protein-glutamine gamma-glutamyltransferase [tgl]. 1 245 43.027 T 11-10-2018 IPR020916 Protein-glutamine gamma-glutamyltransferase, bacteria GO:0003810 UP12_17225 7f072626e4e0d2de765762d964316ccb 415 Gene3D G3DSA:3.40.640.10 33 283 2.9E-188 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_17225 7f072626e4e0d2de765762d964316ccb 415 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 53.335 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UP12_17225 7f072626e4e0d2de765762d964316ccb 415 PIRSF PIRSF000412 1 414 1.6E-172 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UP12_17225 7f072626e4e0d2de765762d964316ccb 415 Pfam PF00464 Serine hydroxymethyltransferase 5 380 7.2E-182 T 11-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UP12_17225 7f072626e4e0d2de765762d964316ccb 415 Gene3D G3DSA:3.90.1150.10 6 389 2.9E-188 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_17225 7f072626e4e0d2de765762d964316ccb 415 SUPERFAMILY SSF53383 2 413 5.84E-182 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_17225 7f072626e4e0d2de765762d964316ccb 415 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 11-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 UP12_07940 4e60728a24bbbcce1c7d77c23780aba4 71 Pfam PF06289 Flagellar protein (FlbD) 1 58 5.1E-27 T 11-10-2018 IPR009384 Swarming motility protein SwrD-like UP12_06740 247fa37325ac20a34c350f65b189ecab 266 SUPERFAMILY SSF55797 142 263 4.06E-28 T 11-10-2018 IPR035940 CAP superfamily UP12_06740 247fa37325ac20a34c350f65b189ecab 266 Pfam PF00188 Cysteine-rich secretory protein family 151 263 4.6E-25 T 11-10-2018 IPR014044 CAP domain UP12_06740 247fa37325ac20a34c350f65b189ecab 266 Gene3D G3DSA:3.40.33.10 18 264 1.2E-66 T 11-10-2018 IPR035940 CAP superfamily UP12_06740 247fa37325ac20a34c350f65b189ecab 266 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 143 265 7.0E-61 T 11-10-2018 IPR014258 CAP domain, YkwD-like UP12_00330 c2bae316ee5df313b3eeaa15fa3b1d67 188 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 107 117 - T 11-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 UP12_00330 c2bae316ee5df313b3eeaa15fa3b1d67 188 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 11-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 UP12_00330 c2bae316ee5df313b3eeaa15fa3b1d67 188 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 178 37.355 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UP12_00330 c2bae316ee5df313b3eeaa15fa3b1d67 188 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 4 185 4.5E-72 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UP12_00330 c2bae316ee5df313b3eeaa15fa3b1d67 188 Gene3D G3DSA:3.40.50.1470 1 188 8.0E-72 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 UP12_00330 c2bae316ee5df313b3eeaa15fa3b1d67 188 Pfam PF01195 Peptidyl-tRNA hydrolase 5 185 2.2E-59 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 UP12_00330 c2bae316ee5df313b3eeaa15fa3b1d67 188 SUPERFAMILY SSF53178 2 185 1.96E-69 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 UP12_16115 ccc616404069951e5bdb897c4bde8ff5 309 SUPERFAMILY SSF161098 93 289 2.22E-14 T 11-10-2018 IPR035906 MetI-like superfamily UP12_16115 ccc616404069951e5bdb897c4bde8ff5 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 298 1.3E-32 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_16115 ccc616404069951e5bdb897c4bde8ff5 309 Gene3D G3DSA:1.10.3720.10 87 302 2.4E-17 T 11-10-2018 IPR035906 MetI-like superfamily UP12_14255 afc676c35e195039f9ab9a6b8238801c 309 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 11 142 1.4E-9 T 11-10-2018 IPR024455 Phage capsid UP12_14255 afc676c35e195039f9ab9a6b8238801c 309 SUPERFAMILY SSF56563 18 305 1.11E-11 T 11-10-2018 UP12_14255 afc676c35e195039f9ab9a6b8238801c 309 Pfam PF05065 Phage capsid family 20 304 2.7E-30 T 11-10-2018 IPR024455 Phage capsid UP12_16445 4f44ba74cad04cb412f38f87ac1fe655 117 ProDom PD072806 SWRA MOTILITY YVZD SWARMING MOTILITY-SWARMING 22 117 2.0E-38 T 11-10-2018 IPR035388 Swarming motility protein SwrA UP12_16445 4f44ba74cad04cb412f38f87ac1fe655 117 Pfam PF17423 Swarming motility protein 1 116 4.7E-60 T 11-10-2018 IPR035388 Swarming motility protein SwrA UP12_13905 4ab6af84a673096bb33d64450e30177f 274 Gene3D G3DSA:3.40.50.1820 10 273 3.1E-62 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13905 4ab6af84a673096bb33d64450e30177f 274 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 26 271 3.0E-83 T 11-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 UP12_13905 4ab6af84a673096bb33d64450e30177f 274 Pfam PF00561 alpha/beta hydrolase fold 28 259 2.0E-20 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_13905 4ab6af84a673096bb33d64450e30177f 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 2.1E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_13905 4ab6af84a673096bb33d64450e30177f 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 2.1E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_13905 4ab6af84a673096bb33d64450e30177f 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 2.1E-8 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_13905 4ab6af84a673096bb33d64450e30177f 274 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 25 272 35.744 T 11-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 UP12_13905 4ab6af84a673096bb33d64450e30177f 274 SUPERFAMILY SSF53474 12 271 6.38E-48 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_15855 4dcfc5a9935825ecd9131ec938e8f99f 217 Gene3D G3DSA:1.10.3720.10 14 207 7.1E-35 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15855 4dcfc5a9935825ecd9131ec938e8f99f 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 198 2.5E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_15855 4dcfc5a9935825ecd9131ec938e8f99f 217 SUPERFAMILY SSF161098 13 196 5.63E-41 T 11-10-2018 IPR035906 MetI-like superfamily UP12_06855 6c0b1ed74c29830a3e7ec15f0d39c623 158 SUPERFAMILY SSF52218 1 146 9.33E-39 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_06855 6c0b1ed74c29830a3e7ec15f0d39c623 158 Pfam PF00258 Flavodoxin 5 134 3.9E-27 T 11-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 UP12_06855 6c0b1ed74c29830a3e7ec15f0d39c623 158 TIGRFAM TIGR01753 flav_short: flavodoxin 4 142 2.1E-43 T 11-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 UP12_06855 6c0b1ed74c29830a3e7ec15f0d39c623 158 Gene3D G3DSA:3.40.50.360 1 144 1.6E-36 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_06855 6c0b1ed74c29830a3e7ec15f0d39c623 158 PRINTS PR00369 Flavodoxin signature 52 63 6.2E-5 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_06855 6c0b1ed74c29830a3e7ec15f0d39c623 158 PRINTS PR00369 Flavodoxin signature 4 17 6.2E-5 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_06855 6c0b1ed74c29830a3e7ec15f0d39c623 158 PRINTS PR00369 Flavodoxin signature 81 91 6.2E-5 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 UP12_16465 cefd93580758ddff4773bc3539c9d9d3 296 Pfam PF02687 FtsX-like permease family 199 292 2.0E-7 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UP12_16465 cefd93580758ddff4773bc3539c9d9d3 296 Gene3D G3DSA:3.30.70.3040 48 156 3.6E-10 T 11-10-2018 UP12_16465 cefd93580758ddff4773bc3539c9d9d3 296 PIRSF PIRSF003097 1 296 1.8E-97 T 11-10-2018 IPR004513 Cell division protein FtsX GO:0016021 UP12_05375 2ce860d8e9438bb1551204ebd55ff816 364 Pfam PF08757 CotH kinase protein 47 353 1.4E-86 T 11-10-2018 IPR014867 Spore coat protein CotH UP12_06625 eba30830150789b118c598a710e38080 218 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 5.9E-89 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UP12_06625 eba30830150789b118c598a710e38080 218 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 217 50.377 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UP12_06625 eba30830150789b118c598a710e38080 218 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 7.7E-87 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UP12_06625 eba30830150789b118c598a710e38080 218 Gene3D G3DSA:3.40.50.620 1 218 2.2E-77 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_06625 eba30830150789b118c598a710e38080 218 PIRSF PIRSF006293 2 218 1.6E-80 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 UP12_06625 eba30830150789b118c598a710e38080 218 SUPERFAMILY SSF52402 3 209 1.85E-66 T 11-10-2018 UP12_08075 bf975df5f8ed6da7b49f7e61789f796c 419 Gene3D G3DSA:2.30.42.10 201 288 8.9E-20 T 11-10-2018 UP12_08075 bf975df5f8ed6da7b49f7e61789f796c 419 SMART SM00228 189 258 0.0031 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_08075 bf975df5f8ed6da7b49f7e61789f796c 419 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 418 7.1E-131 T 11-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 UP12_08075 bf975df5f8ed6da7b49f7e61789f796c 419 Pfam PF13180 PDZ domain 207 265 1.3E-7 T 11-10-2018 IPR001478 PDZ domain GO:0005515 UP12_08075 bf975df5f8ed6da7b49f7e61789f796c 419 SUPERFAMILY SSF50156 173 266 1.58E-17 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 UP12_08075 bf975df5f8ed6da7b49f7e61789f796c 419 Pfam PF02163 Peptidase family M50 6 405 1.2E-80 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 UP12_17165 6a14de5fdbb9f7b674cb2dccfb433666 76 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 9 76 1.1E-22 T 11-10-2018 IPR009526 Protein of unknown function DUF1146 UP12_17165 6a14de5fdbb9f7b674cb2dccfb433666 76 Pfam PF06612 Protein of unknown function (DUF1146) 16 63 1.7E-19 T 11-10-2018 IPR009526 Protein of unknown function DUF1146 UP12_05810 c64e4e71caaf9f268a406d7000990b26 236 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 215 6.9E-80 T 11-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 UP12_05810 c64e4e71caaf9f268a406d7000990b26 236 Pfam PF03070 TENA/THI-4/PQQC family 10 214 1.1E-57 T 11-10-2018 IPR004305 Thiaminase-2/PQQC UP12_05810 c64e4e71caaf9f268a406d7000990b26 236 Gene3D G3DSA:1.20.910.10 1 220 2.8E-63 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UP12_05810 c64e4e71caaf9f268a406d7000990b26 236 SUPERFAMILY SSF48613 3 220 3.42E-67 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UP12_16570 2d06679d071c90555b02b82d820488d8 87 SUPERFAMILY SSF101498 2 84 3.27E-19 T 11-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily UP12_16570 2d06679d071c90555b02b82d820488d8 87 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 2 85 3.0E-17 T 11-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 UP12_16570 2d06679d071c90555b02b82d820488d8 87 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 82 7.1E-15 T 11-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal UP12_11080 4e0e3647c071cde72ee844487baa41fe 131 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 5 131 3.0E-38 T 11-10-2018 UP12_16340 c843fee277aacecd57185a8652935d6f 241 SUPERFAMILY SSF46785 3 85 8.06E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_16340 c843fee277aacecd57185a8652935d6f 241 Pfam PF07702 UTRA domain 96 234 5.6E-42 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_16340 c843fee277aacecd57185a8652935d6f 241 Gene3D G3DSA:3.40.1410.10 77 241 3.3E-52 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_16340 c843fee277aacecd57185a8652935d6f 241 SMART SM00866 95 234 3.0E-43 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 UP12_16340 c843fee277aacecd57185a8652935d6f 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.7E-11 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_16340 c843fee277aacecd57185a8652935d6f 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.7E-11 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_16340 c843fee277aacecd57185a8652935d6f 241 Gene3D G3DSA:1.10.10.10 9 76 2.8E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16340 c843fee277aacecd57185a8652935d6f 241 SUPERFAMILY SSF64288 62 240 2.04E-55 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily UP12_16340 c843fee277aacecd57185a8652935d6f 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.9E-20 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_16340 c843fee277aacecd57185a8652935d6f 241 SMART SM00345 15 74 9.1E-21 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_14165 653badc4d93136e8b87ccb5e7cb7c45d 127 Pfam PF12571 Phage tail-collar fibre protein 5 113 2.3E-8 T 11-10-2018 IPR022225 Phage tail fibre protein UP12_10820 9108096f505c9d033e548201e6f39f6c 154 Pfam PF01584 CheW-like domain 6 139 9.1E-26 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_10820 9108096f505c9d033e548201e6f39f6c 154 SMART SM00260 1 136 2.8E-18 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_10820 9108096f505c9d033e548201e6f39f6c 154 Gene3D G3DSA:2.40.50.180 24 90 3.8E-27 T 11-10-2018 UP12_10820 9108096f505c9d033e548201e6f39f6c 154 SUPERFAMILY SSF50341 2 140 2.22E-28 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 UP12_10820 9108096f505c9d033e548201e6f39f6c 154 Gene3D G3DSA:2.30.30.40 7 130 3.8E-27 T 11-10-2018 UP12_14970 072127a276eb46ad210e0160df03fcb2 291 Pfam PF00348 Polyprenyl synthetase 33 197 9.4E-15 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 UP12_14970 072127a276eb46ad210e0160df03fcb2 291 Gene3D G3DSA:1.10.600.10 6 287 4.3E-30 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_14970 072127a276eb46ad210e0160df03fcb2 291 SUPERFAMILY SSF48576 30 286 2.88E-30 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily UP12_08015 c18622d8710eef27a33625565701e5f1 153 Gene3D G3DSA:2.40.50.180 29 95 1.8E-36 T 11-10-2018 UP12_08015 c18622d8710eef27a33625565701e5f1 153 Pfam PF01584 CheW-like domain 11 145 2.2E-30 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_08015 c18622d8710eef27a33625565701e5f1 153 Gene3D G3DSA:2.30.30.40 12 137 1.8E-36 T 11-10-2018 UP12_08015 c18622d8710eef27a33625565701e5f1 153 SUPERFAMILY SSF50341 10 145 3.14E-34 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 UP12_08015 c18622d8710eef27a33625565701e5f1 153 SMART SM00260 6 143 1.1E-36 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 UP12_07880 36d5178bcea020cc4470bb1a2c6a9c48 129 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 4 125 6.1E-36 T 11-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 UP12_07880 36d5178bcea020cc4470bb1a2c6a9c48 129 PIRSF PIRSF002889 2 128 1.5E-33 T 11-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 UP12_07880 36d5178bcea020cc4470bb1a2c6a9c48 129 Pfam PF00460 Flagella basal body rod protein 9 38 3.4E-9 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 UP12_07880 36d5178bcea020cc4470bb1a2c6a9c48 129 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site UP12_08760 91b25094b46b3061cff7886cd142efbd 47 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 47 18.377 T 11-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 UP12_08760 91b25094b46b3061cff7886cd142efbd 47 Pfam PF08177 Small acid-soluble spore protein N family 1 46 6.3E-27 T 11-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 UP12_14715 88af79bcd75324add8ee817ecdef6d4d 174 SUPERFAMILY SSF52317 6 171 5.6E-45 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_14715 88af79bcd75324add8ee817ecdef6d4d 174 Gene3D G3DSA:3.40.50.880 2 174 1.9E-47 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_14715 88af79bcd75324add8ee817ecdef6d4d 174 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 7 171 5.3E-51 T 11-10-2018 IPR006286 Deglycase PfpI UP12_14715 88af79bcd75324add8ee817ecdef6d4d 174 Pfam PF01965 DJ-1/PfpI family 6 167 3.5E-45 T 11-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 UP12_14435 59e724d7af052048800df3972151983d 234 Gene3D G3DSA:3.60.15.10 4 231 1.2E-23 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_14435 59e724d7af052048800df3972151983d 234 SUPERFAMILY SSF56281 8 215 1.06E-26 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_14435 59e724d7af052048800df3972151983d 234 Pfam PF12706 Beta-lactamase superfamily domain 49 143 6.7E-9 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_01575 723c3925362787d7a3e5d4fb9d6baf57 309 PRINTS PR00069 Aldo-keto reductase signature 110 128 3.2E-16 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01575 723c3925362787d7a3e5d4fb9d6baf57 309 PRINTS PR00069 Aldo-keto reductase signature 44 68 3.2E-16 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01575 723c3925362787d7a3e5d4fb9d6baf57 309 PRINTS PR00069 Aldo-keto reductase signature 241 265 3.2E-16 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01575 723c3925362787d7a3e5d4fb9d6baf57 309 PRINTS PR00069 Aldo-keto reductase signature 141 158 3.2E-16 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_01575 723c3925362787d7a3e5d4fb9d6baf57 309 SUPERFAMILY SSF51430 2 308 1.31E-94 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_01575 723c3925362787d7a3e5d4fb9d6baf57 309 Pfam PF00248 Aldo/keto reductase family 15 307 1.5E-75 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain UP12_01575 723c3925362787d7a3e5d4fb9d6baf57 309 Gene3D G3DSA:3.20.20.100 1 309 1.2E-114 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_13495 2b7124464effe5389efd5ce7eaf9c6c9 213 Gene3D G3DSA:3.40.50.150 1 212 5.1E-72 T 11-10-2018 UP12_13495 2b7124464effe5389efd5ce7eaf9c6c9 213 Pfam PF02390 Putative methyltransferase 39 206 2.2E-49 T 11-10-2018 UP12_13495 2b7124464effe5389efd5ce7eaf9c6c9 213 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 29.504 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 UP12_13495 2b7124464effe5389efd5ce7eaf9c6c9 213 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 209 2.0E-61 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 UP12_13495 2b7124464effe5389efd5ce7eaf9c6c9 213 SUPERFAMILY SSF53335 26 208 7.06E-33 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_08050 31187c161a7b09d9acd332ff6780a694 240 Gene3D G3DSA:3.40.1160.10 2 239 1.9E-81 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_08050 31187c161a7b09d9acd332ff6780a694 240 PIRSF PIRSF005650 1 240 1.4E-97 T 11-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 UP12_08050 31187c161a7b09d9acd332ff6780a694 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 1.5E-102 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 UP12_08050 31187c161a7b09d9acd332ff6780a694 240 SUPERFAMILY SSF53633 4 238 3.27E-74 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily UP12_08050 31187c161a7b09d9acd332ff6780a694 240 Pfam PF00696 Amino acid kinase family 7 217 4.4E-28 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 UP12_08050 31187c161a7b09d9acd332ff6780a694 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.052 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 UP12_14975 eb819b52264d0dfd0c6e2497d281cd96 46 Pfam PF08181 DegQ (SacQ) family 1 46 2.3E-32 T 11-10-2018 IPR012554 Degradation enzyme regulation protein DegQ GO:1900192 UP12_14975 eb819b52264d0dfd0c6e2497d281cd96 46 ProDom PD014716 DEGQ ENZYME DEGRADATION SACQ REGULATORY REGULATION FACTOR 1 42 7.0E-12 T 11-10-2018 IPR012554 Degradation enzyme regulation protein DegQ GO:1900192 UP12_03485 7d1a2c56ee3a0ea2e64988336e6aab3d 399 Pfam PF07690 Major Facilitator Superfamily 12 337 2.4E-10 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_03485 7d1a2c56ee3a0ea2e64988336e6aab3d 399 SUPERFAMILY SSF103473 3 397 1.57E-30 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_03485 7d1a2c56ee3a0ea2e64988336e6aab3d 399 Gene3D G3DSA:1.20.1250.20 1 398 4.2E-27 T 11-10-2018 UP12_01630 fc1b4044d8be82292b56e51f3f8fe78a 200 Gene3D G3DSA:2.60.60.30 19 197 3.5E-61 T 11-10-2018 UP12_01630 fc1b4044d8be82292b56e51f3f8fe78a 200 Pfam PF02342 TerD domain 2 199 1.0E-74 T 11-10-2018 IPR003325 TerD domain UP12_05850 08adc2b00b753e86184e5bcd802b1404 222 Pfam PF14153 Spore coat protein CotO 4 222 2.8E-59 T 11-10-2018 IPR025439 Spore coat protein CotO UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 SUPERFAMILY SSF53187 8 393 1.02E-87 T 11-10-2018 UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 SUPERFAMILY SSF55031 188 306 3.14E-28 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 Gene3D G3DSA:3.40.630.10 21 379 3.7E-144 T 11-10-2018 UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 Pfam PF07687 Peptidase dimerisation domain 193 285 8.1E-8 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 PIRSF PIRSF005962 5 395 4.7E-133 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 Gene3D G3DSA:3.30.70.360 188 302 3.7E-144 T 11-10-2018 UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 382 3.8E-118 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 UP12_05130 a46e39434c0e99c4aca31eb8244fd485 395 Pfam PF01546 Peptidase family M20/M25/M40 79 391 3.1E-32 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_09370 698c169a04718295952a4e96d3a0229d 386 Pfam PF00480 ROK family 83 376 2.6E-85 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_09370 698c169a04718295952a4e96d3a0229d 386 SUPERFAMILY SSF46785 8 74 9.74E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_09370 698c169a04718295952a4e96d3a0229d 386 Pfam PF13412 Winged helix-turn-helix DNA-binding 13 56 5.8E-7 T 11-10-2018 UP12_09370 698c169a04718295952a4e96d3a0229d 386 SUPERFAMILY SSF53067 81 378 6.48E-56 T 11-10-2018 UP12_09370 698c169a04718295952a4e96d3a0229d 386 Gene3D G3DSA:3.30.420.40 204 358 7.1E-89 T 11-10-2018 UP12_09370 698c169a04718295952a4e96d3a0229d 386 Gene3D G3DSA:1.10.10.10 10 76 9.2E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_09370 698c169a04718295952a4e96d3a0229d 386 ProSitePatterns PS01125 ROK family signature. 213 240 - T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_09370 698c169a04718295952a4e96d3a0229d 386 Gene3D G3DSA:3.30.420.40 82 376 7.1E-89 T 11-10-2018 UP12_11830 e5fb4828d0324f574cf17e094777a410 237 Gene3D G3DSA:1.10.3720.10 3 230 1.3E-48 T 11-10-2018 IPR035906 MetI-like superfamily UP12_11830 e5fb4828d0324f574cf17e094777a410 237 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 123 5.6E-21 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_11830 e5fb4828d0324f574cf17e094777a410 237 SUPERFAMILY SSF161098 14 214 1.05E-38 T 11-10-2018 IPR035906 MetI-like superfamily UP12_11830 e5fb4828d0324f574cf17e094777a410 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 229 7.4E-16 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_03830 88ea2c0a7c30b81bb689ba24f6791a06 218 Pfam PF13489 Methyltransferase domain 54 165 2.3E-13 T 11-10-2018 UP12_03830 88ea2c0a7c30b81bb689ba24f6791a06 218 Gene3D G3DSA:3.40.50.150 18 213 1.5E-20 T 11-10-2018 UP12_03830 88ea2c0a7c30b81bb689ba24f6791a06 218 SUPERFAMILY SSF53335 20 204 9.62E-22 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_17140 436967221b6c0b853bf08ee0de33f9a4 225 Pfam PF00092 von Willebrand factor type A domain 33 215 3.4E-14 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_17140 436967221b6c0b853bf08ee0de33f9a4 225 Gene3D G3DSA:3.40.50.410 143 225 2.4E-15 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_17140 436967221b6c0b853bf08ee0de33f9a4 225 Gene3D G3DSA:3.40.50.410 17 142 1.9E-11 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_17140 436967221b6c0b853bf08ee0de33f9a4 225 SUPERFAMILY SSF53300 19 218 9.49E-25 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily UP12_17140 436967221b6c0b853bf08ee0de33f9a4 225 SMART SM00327 30 220 2.0E-14 T 11-10-2018 IPR002035 von Willebrand factor, type A UP12_04285 4ca9210b95d07934ca3deeb79dbf4d56 51 ProDom PD053407 YFHD 16 51 2.0E-4 T 11-10-2018 UP12_04285 4ca9210b95d07934ca3deeb79dbf4d56 51 Pfam PF14151 YfhD-like protein 3 51 4.4E-15 T 11-10-2018 IPR025435 YfhD-like protein UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 11-10-2018 IPR019808 Histidine triad, conserved site UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 Pfam PF01230 HIT domain 13 106 3.6E-28 T 11-10-2018 IPR001310 Histidine triad (HIT) protein UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 Gene3D G3DSA:1.20.5.1170 114 142 1.4E-8 T 11-10-2018 UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 Gene3D G3DSA:3.30.428.10 1 112 2.8E-40 T 11-10-2018 IPR036265 HIT-like superfamily UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 SUPERFAMILY SSF54197 2 135 1.52E-45 T 11-10-2018 IPR036265 HIT-like superfamily UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 PRINTS PR00332 Histidine triad family signature 93 103 1.5E-17 T 11-10-2018 IPR001310 Histidine triad (HIT) protein UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 PRINTS PR00332 Histidine triad family signature 5 21 1.5E-17 T 11-10-2018 IPR001310 Histidine triad (HIT) protein UP12_05110 54f1e53426ce6a17c2f762982f90c1a0 142 PRINTS PR00332 Histidine triad family signature 26 44 1.5E-17 T 11-10-2018 IPR001310 Histidine triad (HIT) protein UP12_15685 44edb6b97f44608aa11c6827892fe736 281 Gene3D G3DSA:3.20.20.100 1 278 4.7E-127 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_15685 44edb6b97f44608aa11c6827892fe736 281 SUPERFAMILY SSF51430 8 269 3.4E-99 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily UP12_15685 44edb6b97f44608aa11c6827892fe736 281 Pfam PF00248 Aldo/keto reductase family 29 264 3.3E-55 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain UP12_15685 44edb6b97f44608aa11c6827892fe736 281 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 44 61 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 PRINTS PR00069 Aldo-keto reductase signature 199 223 4.6E-49 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 PRINTS PR00069 Aldo-keto reductase signature 96 114 4.6E-49 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 PRINTS PR00069 Aldo-keto reductase signature 162 191 4.6E-49 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 PRINTS PR00069 Aldo-keto reductase signature 40 64 4.6E-49 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 PRINTS PR00069 Aldo-keto reductase signature 128 145 4.6E-49 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 232 247 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 UP12_15685 44edb6b97f44608aa11c6827892fe736 281 PIRSF PIRSF000097 2 281 1.1E-93 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 UP12_09205 35b0a42ab070b764f2e47f7f7e540bec 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 12 358 4.8E-50 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_09205 35b0a42ab070b764f2e47f7f7e540bec 366 Pfam PF03845 Spore germination protein 11 322 3.2E-67 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 Pfam PF00875 DNA photolyase 4 165 2.6E-29 T 11-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 Gene3D G3DSA:3.40.50.620 5 206 3.6E-60 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 322 334 - T 11-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 Gene3D G3DSA:1.10.579.10 291 477 1.7E-79 T 11-10-2018 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 Gene3D G3DSA:1.25.40.80 131 286 3.6E-60 T 11-10-2018 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 Pfam PF03441 FAD binding domain of DNA photolyase 273 472 2.6E-85 T 11-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 SUPERFAMILY SSF48173 205 476 6.02E-105 T 11-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 SUPERFAMILY SSF52425 3 173 5.23E-33 T 11-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 PRINTS PR00147 DNA photolyase signature 322 338 1.5E-26 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 PRINTS PR00147 DNA photolyase signature 342 360 1.5E-26 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 PRINTS PR00147 DNA photolyase signature 142 158 1.5E-26 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UP12_07195 c7a9311420dfc36d75eb39de3f5eccff 477 PRINTS PR00147 DNA photolyase signature 381 395 1.5E-26 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 UP12_15535 d2ef3033e0f5c2cb8bc07f96523aa092 122 PRINTS PR01077 Claudin family signature 2 23 1.2E-5 T 11-10-2018 UP12_15535 d2ef3033e0f5c2cb8bc07f96523aa092 122 PRINTS PR01077 Claudin family signature 39 63 1.2E-5 T 11-10-2018 UP12_18145 23350353ced1d7052f6c1582a4c22f4d 109 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 11 102 5.1E-31 T 11-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 UP12_18145 23350353ced1d7052f6c1582a4c22f4d 109 PIRSF PIRSF000699 1 109 1.0E-32 T 11-10-2018 IPR003188 Phosphotransferase system, lactose/cellobiose-type IIA subunit GO:0009401 UP12_18145 23350353ced1d7052f6c1582a4c22f4d 109 SUPERFAMILY SSF46973 5 103 5.36E-31 T 11-10-2018 IPR036542 Phosphotransferase system, lactose/cellobiose-type IIA subunit superfamily GO:0009401 UP12_18145 23350353ced1d7052f6c1582a4c22f4d 109 Gene3D G3DSA:1.20.58.280 2 107 1.0E-32 T 11-10-2018 UP12_10460 fff673a39503022160b3964cace45641 117 Gene3D G3DSA:3.40.630.30 9 113 4.2E-13 T 11-10-2018 UP12_10460 fff673a39503022160b3964cace45641 117 SUPERFAMILY SSF55729 5 97 2.16E-13 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_10460 fff673a39503022160b3964cace45641 117 Pfam PF00583 Acetyltransferase (GNAT) family 33 109 3.4E-10 T 11-10-2018 IPR000182 GNAT domain UP12_14780 e18a9c51c8b809d1cc3079b60e232ce5 133 SUPERFAMILY SSF160755 1 132 1.7E-37 T 11-10-2018 IPR036491 YugN-like superfamily UP12_14780 e18a9c51c8b809d1cc3079b60e232ce5 133 Pfam PF08868 YugN-like family 4 132 8.2E-55 T 11-10-2018 IPR014967 Uncharacterised protein family, YugN-like UP12_14780 e18a9c51c8b809d1cc3079b60e232ce5 133 Gene3D G3DSA:3.30.310.100 3 115 8.9E-30 T 11-10-2018 IPR036491 YugN-like superfamily UP12_02875 07467a17ca239dfbd828ab388cd03688 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 53 8.6E-12 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02875 07467a17ca239dfbd828ab388cd03688 192 Gene3D G3DSA:1.10.357.10 3 177 2.1E-23 T 11-10-2018 UP12_02875 07467a17ca239dfbd828ab388cd03688 192 SUPERFAMILY SSF46689 7 68 2.0E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_02875 07467a17ca239dfbd828ab388cd03688 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.9E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02875 07467a17ca239dfbd828ab388cd03688 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.9E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_10345 9ce29a7d14bc794e502bff401f303782 253 SUPERFAMILY SSF54106 203 250 8.76E-6 T 11-10-2018 UP12_10345 9ce29a7d14bc794e502bff401f303782 253 Pfam PF01476 LysM domain 205 250 4.5E-7 T 11-10-2018 IPR018392 LysM domain UP12_10345 9ce29a7d14bc794e502bff401f303782 253 SMART SM00257 204 250 1.8E-7 T 11-10-2018 IPR018392 LysM domain UP12_10345 9ce29a7d14bc794e502bff401f303782 253 Gene3D G3DSA:3.10.350.10 186 253 6.5E-10 T 11-10-2018 IPR036779 LysM domain superfamily UP12_17070 db1ddd54e08056caefbfa3fe276c12b7 169 SUPERFAMILY SSF55729 11 168 4.13E-32 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_17070 db1ddd54e08056caefbfa3fe276c12b7 169 Gene3D G3DSA:3.40.630.30 4 169 2.5E-47 T 11-10-2018 UP12_17070 db1ddd54e08056caefbfa3fe276c12b7 169 Pfam PF13420 Acetyltransferase (GNAT) domain 11 161 4.4E-18 T 11-10-2018 UP12_02060 e31dcd1567789e353e4703d1b3cf9755 186 Gene3D G3DSA:2.40.260.10 23 186 3.0E-40 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_02060 e31dcd1567789e353e4703d1b3cf9755 186 Pfam PF04203 Sortase family 64 186 4.0E-27 T 11-10-2018 IPR005754 Sortase family UP12_02060 e31dcd1567789e353e4703d1b3cf9755 186 SUPERFAMILY SSF63817 17 186 8.63E-34 T 11-10-2018 IPR023365 Sortase domain superfamily UP12_02060 e31dcd1567789e353e4703d1b3cf9755 186 TIGRFAM TIGR01076 sortase_fam: sortase 62 186 2.2E-39 T 11-10-2018 IPR005754 Sortase family UP12_16565 248d92dde8e1165706f2abf6b15b4551 160 SUPERFAMILY SSF140566 2 130 1.7E-21 T 11-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 UP12_16565 248d92dde8e1165706f2abf6b15b4551 160 Gene3D G3DSA:1.20.58.300 3 130 4.8E-9 T 11-10-2018 UP12_16565 248d92dde8e1165706f2abf6b15b4551 160 Pfam PF05130 FlgN protein 1 145 6.4E-29 T 11-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 UP12_04825 513b9e9a41e86db9137f464870aeadf5 82 Pfam PF14148 YhdB-like protein 1 70 9.8E-40 T 11-10-2018 IPR025431 YhdB-like protein UP12_04685 23b00139855859559ec920ad1bda71b5 174 Pfam PF03358 NADPH-dependent FMN reductase 35 120 5.2E-12 T 11-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 UP12_04685 23b00139855859559ec920ad1bda71b5 174 SUPERFAMILY SSF52218 1 170 4.85E-44 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_04685 23b00139855859559ec920ad1bda71b5 174 Gene3D G3DSA:3.40.50.360 1 174 3.9E-48 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 11 363 1.3E-133 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 SUPERFAMILY SSF52440 7 92 2.59E-24 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 SUPERFAMILY SSF51246 310 371 4.39E-12 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 Gene3D G3DSA:3.30.470.20 186 373 9.8E-73 T 11-10-2018 UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 11 360 42.093 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 Pfam PF02222 ATP-grasp domain 117 285 6.1E-60 T 11-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 SUPERFAMILY SSF56059 107 305 1.15E-62 T 11-10-2018 UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 Gene3D G3DSA:3.40.50.20 2 115 6.9E-42 T 11-10-2018 UP12_03340 387d8818c6417b0f3cddb70d548bc60c 380 Gene3D G3DSA:3.30.1490.20 117 185 2.4E-24 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 UP12_16235 dfc3d5424b6330c0aa9d94cdef477c61 465 Pfam PF00877 NlpC/P60 family 349 461 4.1E-28 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_16235 dfc3d5424b6330c0aa9d94cdef477c61 465 SUPERFAMILY SSF54001 336 462 3.04E-29 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_16235 dfc3d5424b6330c0aa9d94cdef477c61 465 Gene3D G3DSA:3.90.1720.10 157 462 6.0E-32 T 11-10-2018 UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 TIGRFAM TIGR03404 bicupin_oxalic: bicupin, oxalate decarboxylase family 15 380 1.0E-179 T 11-10-2018 IPR017774 Bicupin, oxalate decarboxylase/oxidase GO:0033609 KEGG: 00630+4.1.1.2|MetaCyc: PWY-6698 UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 Gene3D G3DSA:2.60.120.10 9 372 2.1E-174 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 Pfam PF00190 Cupin 58 191 1.3E-23 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 Pfam PF00190 Cupin 230 348 3.5E-22 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 SUPERFAMILY SSF51182 11 378 2.87E-101 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 SMART SM00835 229 370 7.8E-26 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 SMART SM00835 51 193 4.8E-19 T 11-10-2018 IPR006045 Cupin 1 GO:0045735 UP12_04340 aa7bc3fb5210f7ea24e4290954270639 387 Gene3D G3DSA:2.60.120.10 57 230 2.1E-174 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_19340 8d1d4a255e85a05eb9ec1c3d722e3733 222 Gene3D G3DSA:3.40.1350.10 57 165 1.1E-12 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 UP12_19340 8d1d4a255e85a05eb9ec1c3d722e3733 222 Pfam PF04471 Restriction endonuclease 55 163 3.3E-31 T 11-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 UP12_19340 8d1d4a255e85a05eb9ec1c3d722e3733 222 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 190 220 9.8E-8 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 UP12_19340 8d1d4a255e85a05eb9ec1c3d722e3733 222 SUPERFAMILY SSF52980 58 165 5.36E-23 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 UP12_18740 dbd813e16f42a2934b3b02a9ce2ccd08 169 SUPERFAMILY SSF54518 2 152 6.02E-32 T 11-10-2018 IPR025659 Tubby-like, C-terminal UP12_18740 dbd813e16f42a2934b3b02a9ce2ccd08 169 Pfam PF04525 LURP-one-related 6 147 3.4E-13 T 11-10-2018 IPR007612 LURP-one-related UP12_18740 dbd813e16f42a2934b3b02a9ce2ccd08 169 Gene3D G3DSA:3.20.90.20 1 158 3.2E-7 T 11-10-2018 IPR038595 LURP-one-related superfamily UP12_01480 1f1d0e9b907e49d13079b51702fc6d2b 182 SUPERFAMILY SSF55729 5 149 1.05E-26 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_01480 1f1d0e9b907e49d13079b51702fc6d2b 182 Gene3D G3DSA:3.40.630.30 3 151 1.7E-28 T 11-10-2018 UP12_01480 1f1d0e9b907e49d13079b51702fc6d2b 182 PIRSF PIRSF037663 6 172 1.9E-13 T 11-10-2018 IPR017255 Acetyltransferase, GNAT, predicted UP12_01480 1f1d0e9b907e49d13079b51702fc6d2b 182 Pfam PF00583 Acetyltransferase (GNAT) family 45 147 4.1E-17 T 11-10-2018 IPR000182 GNAT domain UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 SUPERFAMILY SSF53933 55 162 7.65E-39 T 11-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 Gene3D G3DSA:3.10.450.30 47 162 1.2E-47 T 11-10-2018 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 Pfam PF00545 ribonuclease 72 160 1.4E-23 T 11-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 PIRSF PIRSF001013 9 162 2.8E-77 T 11-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 PRINTS PR00117 Barnase signature 59 76 4.5E-57 T 11-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 PRINTS PR00117 Barnase signature 120 139 4.5E-57 T 11-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 PRINTS PR00117 Barnase signature 99 117 4.5E-57 T 11-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 PRINTS PR00117 Barnase signature 79 96 4.5E-57 T 11-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 UP12_16180 a70ffc3928acb1ab02ad2a5ce72090f8 162 PRINTS PR00117 Barnase signature 142 160 4.5E-57 T 11-10-2018 IPR001887 Barnase GO:0003723|GO:0004521 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 SUPERFAMILY SSF103473 1 390 4.05E-75 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_02945 a18106a239dde107c75b7e5db03955c5 398 Gene3D G3DSA:1.20.1250.20 4 390 5.1E-72 T 11-10-2018 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 PRINTS PR01035 Tetracycline resistance protein signature 164 184 1.3E-21 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 PRINTS PR01035 Tetracycline resistance protein signature 341 364 1.3E-21 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 PRINTS PR01035 Tetracycline resistance protein signature 78 102 1.3E-21 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 PRINTS PR01035 Tetracycline resistance protein signature 21 37 1.3E-21 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 PRINTS PR01035 Tetracycline resistance protein signature 136 158 1.3E-21 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 PRINTS PR01035 Tetracycline resistance protein signature 253 273 1.3E-21 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_02945 a18106a239dde107c75b7e5db03955c5 398 Pfam PF07690 Major Facilitator Superfamily 16 350 2.4E-53 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 Gene3D G3DSA:3.40.50.720 1 202 7.7E-71 T 11-10-2018 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 Gene3D G3DSA:1.10.1040.10 204 372 9.3E-59 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 147 358 2.0E-53 T 11-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 SUPERFAMILY SSF51735 1 199 3.33E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 SUPERFAMILY SSF48179 201 368 2.96E-40 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 PRINTS PR00084 Mannitol dehydrogenase signature 113 126 2.9E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 2.9E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 PRINTS PR00084 Mannitol dehydrogenase signature 149 162 2.9E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 PRINTS PR00084 Mannitol dehydrogenase signature 167 182 2.9E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 371 39.805 T 11-10-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 122 9.4E-23 T 11-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_02210 04131720bb7a14e02e883c1cf1cf52c3 373 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 149 161 - T 11-10-2018 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 UP12_12765 0d2db1226575345a2203a22527fc72b6 283 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 185 256 2.1E-27 T 11-10-2018 IPR011741 Phage conserved hypothetical protein, C-terminal UP12_12765 0d2db1226575345a2203a22527fc72b6 283 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 183 257 1.2E-25 T 11-10-2018 IPR011741 Phage conserved hypothetical protein, C-terminal UP12_17640 98fa79db605f9baca8107e66ffd3a3a6 284 Gene3D G3DSA:3.40.50.720 2 264 1.4E-97 T 11-10-2018 UP12_17640 98fa79db605f9baca8107e66ffd3a3a6 284 Pfam PF04321 RmlD substrate binding domain 1 276 9.5E-100 T 11-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 UP12_17640 98fa79db605f9baca8107e66ffd3a3a6 284 SUPERFAMILY SSF51735 1 276 1.71E-88 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_17640 98fa79db605f9baca8107e66ffd3a3a6 284 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 276 9.5E-99 T 11-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 UP12_17640 98fa79db605f9baca8107e66ffd3a3a6 284 Gene3D G3DSA:3.90.25.10 159 270 1.4E-97 T 11-10-2018 UP12_09770 341d84c9a6b5ccadd372e91c765b3ec2 212 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 6 206 1.4E-68 T 11-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 UP12_09770 341d84c9a6b5ccadd372e91c765b3ec2 212 Pfam PF03006 Haemolysin-III related 2 197 9.3E-39 T 11-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 UP12_14590 aff37c4ad1cfc23a181be3220f568e41 147 Pfam PF09393 Phage tail tube protein 2 141 6.3E-52 T 11-10-2018 IPR018989 Phage tail tube protein UP12_14590 aff37c4ad1cfc23a181be3220f568e41 147 Gene3D G3DSA:2.30.110.40 1 142 2.9E-59 T 11-10-2018 IPR038628 XkdM-like superfamily UP12_14590 aff37c4ad1cfc23a181be3220f568e41 147 SUPERFAMILY SSF69279 6 142 6.46E-49 T 11-10-2018 UP12_00935 ee57f2c7b517388c72777d6c8e6b3ebc 237 SUPERFAMILY SSF53187 41 230 4.39E-53 T 11-10-2018 UP12_00935 ee57f2c7b517388c72777d6c8e6b3ebc 237 SMART SM00646 115 226 6.3E-37 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_00935 ee57f2c7b517388c72777d6c8e6b3ebc 237 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 41 228 7.5E-84 T 11-10-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 UP12_00935 ee57f2c7b517388c72777d6c8e6b3ebc 237 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 43 226 3.1E-49 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 UP12_00935 ee57f2c7b517388c72777d6c8e6b3ebc 237 Gene3D G3DSA:3.40.630.40 39 234 8.6E-56 T 11-10-2018 UP12_04580 9180a998b428d7f00bdbcba245f13045 229 Gene3D G3DSA:2.30.320.10 2 228 2.2E-12 T 11-10-2018 IPR035948 YwqG-like superfamily UP12_04580 9180a998b428d7f00bdbcba245f13045 229 Pfam PF09234 Domain of unknown function (DUF1963) 32 218 2.3E-16 T 11-10-2018 IPR015315 Protein of unknown function DUF1963 UP12_04580 9180a998b428d7f00bdbcba245f13045 229 SUPERFAMILY SSF103032 32 218 1.23E-9 T 11-10-2018 IPR035948 YwqG-like superfamily UP12_15630 6cf1e9a166e3ffebc71ffa9849753176 340 SUPERFAMILY SSF81345 4 338 1.02E-87 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15630 6cf1e9a166e3ffebc71ffa9849753176 340 Gene3D G3DSA:1.10.3470.10 9 340 2.7E-100 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15630 6cf1e9a166e3ffebc71ffa9849753176 340 Pfam PF01032 FecCD transport family 23 338 2.1E-97 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.0E-46 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 1.4E-43 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 Gene3D G3DSA:3.30.470.130 1 449 3.3E-199 T 11-10-2018 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 447 5.7E-242 T 11-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 SUPERFAMILY SSF56059 83 349 6.01E-71 T 11-10-2018 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 SUPERFAMILY SSF52440 1 113 2.16E-50 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 SUPERFAMILY SSF51246 332 445 2.62E-47 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 SMART SM00878 337 443 6.3E-70 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_11000 5b5dca0ea8c355330d774b421e282d39 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 3.8E-82 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 UP12_08785 e4c9f789190b465b41505b0cb00ee69a 193 SMART SM01207 8 183 4.6E-77 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UP12_08785 e4c9f789190b465b41505b0cb00ee69a 193 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 191 19.955 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UP12_08785 e4c9f789190b465b41505b0cb00ee69a 193 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 1 192 6.7E-68 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UP12_08785 e4c9f789190b465b41505b0cb00ee69a 193 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 182 2.3E-50 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UP12_07390 711189ba8675d64e46c756a3c7efae21 259 Gene3D G3DSA:3.10.20.310 54 121 4.5E-6 T 11-10-2018 UP12_07390 711189ba8675d64e46c756a3c7efae21 259 Hamap MF_00912 Cell division protein DivIB [divIB]. 13 253 29.611 T 11-10-2018 IPR026580 Cell division protein DivIB UP12_07390 711189ba8675d64e46c756a3c7efae21 259 Pfam PF08478 POTRA domain, FtsQ-type 54 123 1.5E-17 T 11-10-2018 IPR013685 POTRA domain, FtsQ-type UP12_07390 711189ba8675d64e46c756a3c7efae21 259 Gene3D G3DSA:3.40.50.10960 122 236 7.0E-37 T 11-10-2018 UP12_07390 711189ba8675d64e46c756a3c7efae21 259 Pfam PF03799 Cell division protein FtsQ 127 234 9.5E-7 T 11-10-2018 IPR005548 Cell division protein FtsQ/DivIB UP12_02025 a27c8035e3da0f95ca43c5c41918d03a 246 Gene3D G3DSA:3.40.50.1820 4 237 1.0E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02025 a27c8035e3da0f95ca43c5c41918d03a 246 SUPERFAMILY SSF53474 11 234 4.5E-42 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02025 a27c8035e3da0f95ca43c5c41918d03a 246 SMART SM00824 Thioesterase 18 185 0.0022 T 11-10-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 UP12_02025 a27c8035e3da0f95ca43c5c41918d03a 246 Pfam PF00975 Thioesterase domain 16 231 8.8E-44 T 11-10-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 UP12_15675 c700a2ecab9deafec8341fece3043866 258 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 38 254 2.2E-64 T 11-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 UP12_15675 c700a2ecab9deafec8341fece3043866 258 Gene3D G3DSA:3.40.190.10 35 255 5.9E-76 T 11-10-2018 UP12_15675 c700a2ecab9deafec8341fece3043866 258 PIRSF PIRSF004846 1 258 4.4E-86 T 11-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 UP12_15675 c700a2ecab9deafec8341fece3043866 258 Gene3D G3DSA:3.40.190.10 112 218 5.9E-76 T 11-10-2018 UP12_15675 c700a2ecab9deafec8341fece3043866 258 Pfam PF13531 Bacterial extracellular solute-binding protein 33 256 5.6E-47 T 11-10-2018 UP12_15675 c700a2ecab9deafec8341fece3043866 258 SUPERFAMILY SSF53850 32 256 2.59E-65 T 11-10-2018 UP12_05830 a014390ddd54ef5c5fca88664a1a332e 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 42.21 T 11-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 UP12_05830 a014390ddd54ef5c5fca88664a1a332e 255 SUPERFAMILY SSF110399 1 238 6.15E-81 T 11-10-2018 UP12_05830 a014390ddd54ef5c5fca88664a1a332e 255 Gene3D G3DSA:3.20.20.70 1 255 4.1E-117 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_05830 a014390ddd54ef5c5fca88664a1a332e 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 2.4E-109 T 11-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 UP12_07325 7b88610f5716f18bb9be4ac95637dab5 299 SUPERFAMILY SSF48179 173 290 1.84E-25 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 UP12_07325 7b88610f5716f18bb9be4ac95637dab5 299 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 292 7.5E-67 T 11-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 UP12_07325 7b88610f5716f18bb9be4ac95637dab5 299 Gene3D G3DSA:3.40.50.720 1 170 9.9E-56 T 11-10-2018 UP12_07325 7b88610f5716f18bb9be4ac95637dab5 299 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 176 282 9.5E-29 T 11-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain UP12_07325 7b88610f5716f18bb9be4ac95637dab5 299 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 145 2.5E-28 T 11-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain UP12_07325 7b88610f5716f18bb9be4ac95637dab5 299 SUPERFAMILY SSF51735 2 151 1.13E-20 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_07325 7b88610f5716f18bb9be4ac95637dab5 299 Gene3D G3DSA:1.10.1040.10 171 299 4.1E-41 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 UP12_01975 67b82c59c9a7aecb016dbcdc0f128b71 661 Pfam PF02538 Hydantoinase B/oxoprolinase 4 530 2.3E-142 T 11-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 UP12_04005 5b543dcaac8ef166de053e04224e3536 272 PIRSF PIRSF035875 1 269 6.1E-80 T 11-10-2018 IPR017039 Virulence factor BrkB UP12_04005 5b543dcaac8ef166de053e04224e3536 272 Pfam PF03631 Virulence factor BrkB 14 265 4.6E-72 T 11-10-2018 IPR017039 Virulence factor BrkB UP12_04005 5b543dcaac8ef166de053e04224e3536 272 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 3 264 4.5E-74 T 11-10-2018 IPR017039 Virulence factor BrkB UP12_13350 a6f7f47ae9da262da49429220d92f5a6 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site UP12_13350 a6f7f47ae9da262da49429220d92f5a6 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 4.3E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_13350 a6f7f47ae9da262da49429220d92f5a6 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 4.3E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_13350 a6f7f47ae9da262da49429220d92f5a6 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 5.6E-17 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_13350 a6f7f47ae9da262da49429220d92f5a6 221 SUPERFAMILY SSF46689 6 78 2.82E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_13350 a6f7f47ae9da262da49429220d92f5a6 221 Gene3D G3DSA:1.10.357.10 2 209 8.2E-39 T 11-10-2018 UP12_10035 2f94af0a253c0ed568da2f5e6268f1b9 161 Pfam PF03413 Peptidase propeptide and YPEB domain 100 158 8.6E-6 T 11-10-2018 IPR025711 PepSY domain UP12_10035 2f94af0a253c0ed568da2f5e6268f1b9 161 SUPERFAMILY SSF54403 99 159 1.5E-15 T 11-10-2018 UP12_10035 2f94af0a253c0ed568da2f5e6268f1b9 161 SUPERFAMILY SSF54403 35 98 4.59E-14 T 11-10-2018 UP12_10035 2f94af0a253c0ed568da2f5e6268f1b9 161 Gene3D G3DSA:3.10.450.40 99 161 3.4E-27 T 11-10-2018 UP12_10035 2f94af0a253c0ed568da2f5e6268f1b9 161 Gene3D G3DSA:3.10.450.40 28 98 1.6E-24 T 11-10-2018 UP12_11650 9dda4ebde18a2c1f65a7ef655d2fc6fb 189 Gene3D G3DSA:3.40.50.620 1 188 1.3E-67 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_11650 9dda4ebde18a2c1f65a7ef655d2fc6fb 189 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 187 9.4E-60 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 UP12_11650 9dda4ebde18a2c1f65a7ef655d2fc6fb 189 Pfam PF01467 Cytidylyltransferase-like 6 162 5.6E-35 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_11650 9dda4ebde18a2c1f65a7ef655d2fc6fb 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 4.1E-12 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_11650 9dda4ebde18a2c1f65a7ef655d2fc6fb 189 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 188 33.047 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 UP12_11650 9dda4ebde18a2c1f65a7ef655d2fc6fb 189 SUPERFAMILY SSF52374 1 187 8.44E-57 T 11-10-2018 UP12_00130 9c9bfaffe4c53602f81e538b1868b2ca 158 SUPERFAMILY SSF53927 2 153 1.0E-53 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_00130 9c9bfaffe4c53602f81e538b1868b2ca 158 Gene3D G3DSA:3.40.140.10 1 158 2.8E-61 T 11-10-2018 UP12_00130 9c9bfaffe4c53602f81e538b1868b2ca 158 Pfam PF14437 MafB19-like deaminase 4 149 2.8E-41 T 11-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 UP12_00130 9c9bfaffe4c53602f81e538b1868b2ca 158 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 149 45.707 T 11-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 UP12_00130 9c9bfaffe4c53602f81e538b1868b2ca 158 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UP12_01670 d59bece12a2c769a7eb6375ee4ebf515 538 Pfam PF14266 Putative component of 'biosynthetic module' 41 526 2.0E-163 T 11-10-2018 IPR025647 Putative component of 'biosynthetic module' UP12_06915 c34d0cff66275153e69131f914ab130b 338 Gene3D G3DSA:3.40.50.720 2 250 8.4E-74 T 11-10-2018 UP12_06915 c34d0cff66275153e69131f914ab130b 338 SUPERFAMILY SSF69572 2 327 2.88E-81 T 11-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 UP12_06915 c34d0cff66275153e69131f914ab130b 338 Pfam PF00899 ThiF family 5 241 4.0E-56 T 11-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UP12_03205 46f040a6e8c9d4b4185a59e9899c857f 203 PIRSF PIRSF010372 1 202 6.8E-67 T 11-10-2018 IPR007396 Transcriptional regulator PAI 2-type UP12_03205 46f040a6e8c9d4b4185a59e9899c857f 203 Pfam PF04299 Putative FMN-binding domain 1 160 3.6E-49 T 11-10-2018 IPR007396 Transcriptional regulator PAI 2-type UP12_03205 46f040a6e8c9d4b4185a59e9899c857f 203 Gene3D G3DSA:2.30.110.10 1 201 1.1E-60 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UP12_03205 46f040a6e8c9d4b4185a59e9899c857f 203 SUPERFAMILY SSF50475 9 184 1.71E-40 T 11-10-2018 UP12_05020 dbe7ac9951af4cca5a8eb77e574cf3d6 165 SUPERFAMILY SSF116726 70 157 2.22E-16 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_05020 dbe7ac9951af4cca5a8eb77e574cf3d6 165 PIRSF PIRSF005028 1 162 1.8E-56 T 11-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT UP12_05020 dbe7ac9951af4cca5a8eb77e574cf3d6 165 Gene3D G3DSA:3.30.70.1450 85 160 6.9E-18 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 UP12_05020 dbe7ac9951af4cca5a8eb77e574cf3d6 165 Pfam PF02080 TrkA-C domain 90 157 1.8E-13 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 UP12_07915 ec11dc2d0f8ee3ee45c5883bb8188ac0 147 Pfam PF02050 Flagellar FliJ protein 21 142 1.5E-19 T 11-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 UP12_07915 ec11dc2d0f8ee3ee45c5883bb8188ac0 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 5 143 3.4E-33 T 11-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 UP12_07035 ad09c0948e4d6820fc9eacbe5d1b4220 69 Gene3D G3DSA:3.10.20.730 1 58 5.0E-27 T 11-10-2018 UP12_07035 ad09c0948e4d6820fc9eacbe5d1b4220 69 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 9.0E-24 T 11-10-2018 IPR009907 Protein of unknown function DUF1447 UP12_07035 ad09c0948e4d6820fc9eacbe5d1b4220 69 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 1.3E-29 T 11-10-2018 IPR009907 Protein of unknown function DUF1447 UP12_07035 ad09c0948e4d6820fc9eacbe5d1b4220 69 Hamap MF_01553 UPF0356 protein . 1 69 21.89 T 11-10-2018 IPR009907 Protein of unknown function DUF1447 UP12_13295 7e635a592199420c17604bcc1d305313 195 Pfam PF02525 Flavodoxin-like fold 1 179 6.4E-40 T 11-10-2018 IPR003680 Flavodoxin-like fold UP12_13295 7e635a592199420c17604bcc1d305313 195 SUPERFAMILY SSF52218 1 193 4.5E-47 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_13295 7e635a592199420c17604bcc1d305313 195 Gene3D G3DSA:3.40.50.360 1 194 3.0E-49 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_13285 f02fe2cb1acf39279be7d7d056652c75 643 PIRSF PIRSF018968 1 643 1.1E-152 T 11-10-2018 IPR027022 ABC transporter permease protein, BceB-type GO:0055085 UP12_13285 f02fe2cb1acf39279be7d7d056652c75 643 Pfam PF02687 FtsX-like permease family 85 175 1.1E-6 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 11 260 1.4E-109 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 Pfam PF00106 short chain dehydrogenase 9 202 1.0E-61 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 87 104 1.1E-54 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 15 32 1.1E-54 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 237 256 1.1E-54 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 172 195 1.1E-54 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 211 230 1.1E-54 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 107 127 1.1E-54 T 11-10-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 202 0.0012 T 11-10-2018 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.5E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.5E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.5E-9 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 Gene3D G3DSA:3.40.50.720 1 259 5.0E-79 T 11-10-2018 UP12_18975 3119bddf0fae228f8fae1301b89a3b73 261 SUPERFAMILY SSF51735 8 259 7.28E-79 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_13395 49b390c1dad5be68a73b6d32241ffb68 574 Gene3D G3DSA:3.30.300.30 460 573 6.7E-28 T 11-10-2018 UP12_13395 49b390c1dad5be68a73b6d32241ffb68 574 Gene3D G3DSA:3.40.50.12780 15 457 4.4E-117 T 11-10-2018 UP12_13395 49b390c1dad5be68a73b6d32241ffb68 574 Pfam PF00501 AMP-binding enzyme 51 464 8.4E-93 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 UP12_13395 49b390c1dad5be68a73b6d32241ffb68 574 SUPERFAMILY SSF56801 22 564 3.79E-160 T 11-10-2018 UP12_13395 49b390c1dad5be68a73b6d32241ffb68 574 ProSitePatterns PS00455 Putative AMP-binding domain signature. 213 224 - T 11-10-2018 IPR020845 AMP-binding, conserved site UP12_13395 49b390c1dad5be68a73b6d32241ffb68 574 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 551 1.8E-24 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain UP12_06800 1786c2858f5de70843b495ed9c4ca27e 165 Pfam PF03734 L,D-transpeptidase catalytic domain 57 163 3.2E-20 T 11-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UP12_06800 1786c2858f5de70843b495ed9c4ca27e 165 Pfam PF01476 LysM domain 4 47 1.1E-8 T 11-10-2018 IPR018392 LysM domain UP12_06800 1786c2858f5de70843b495ed9c4ca27e 165 SUPERFAMILY SSF54106 2 47 2.09E-7 T 11-10-2018 UP12_06800 1786c2858f5de70843b495ed9c4ca27e 165 Gene3D G3DSA:3.10.350.10 1 48 3.8E-13 T 11-10-2018 IPR036779 LysM domain superfamily UP12_06800 1786c2858f5de70843b495ed9c4ca27e 165 SMART SM00257 3 47 2.9E-9 T 11-10-2018 IPR018392 LysM domain UP12_06800 1786c2858f5de70843b495ed9c4ca27e 165 SUPERFAMILY SSF141523 56 163 3.66E-35 T 11-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UP12_06800 1786c2858f5de70843b495ed9c4ca27e 165 Gene3D G3DSA:2.40.440.10 49 165 2.2E-44 T 11-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 Pfam PF00271 Helicase conserved C-terminal domain 284 388 1.6E-12 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 SMART SM00487 51 255 1.4E-28 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 SMART SM00490 302 389 9.0E-13 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 Pfam PF09369 Domain of unknown function (DUF1998) 650 728 8.9E-20 T 11-10-2018 IPR018973 DEAD/DEAH-box helicase, putative UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 SUPERFAMILY SSF52540 66 400 2.88E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 Gene3D G3DSA:3.40.50.300 262 421 1.6E-20 T 11-10-2018 UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 Pfam PF00270 DEAD/DEAH box helicase 58 229 1.0E-27 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 UP12_09960 2b9e07fe27cdb5a494cf9a60dbd25934 748 Gene3D G3DSA:3.40.50.300 19 246 3.6E-48 T 11-10-2018 UP12_17310 492fbadc6c5affc0913e4d834a5c1a74 321 PIRSF PIRSF004532 1 320 2.1E-148 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UP12_17310 492fbadc6c5affc0913e4d834a5c1a74 321 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 2.4E-159 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UP12_17310 492fbadc6c5affc0913e4d834a5c1a74 321 Gene3D G3DSA:3.40.190.90 122 283 7.6E-132 T 11-10-2018 UP12_17310 492fbadc6c5affc0913e4d834a5c1a74 321 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 309 4.6E-141 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 UP12_17310 492fbadc6c5affc0913e4d834a5c1a74 321 Gene3D G3DSA:3.30.540.10 7 309 7.6E-132 T 11-10-2018 UP12_17310 492fbadc6c5affc0913e4d834a5c1a74 321 SUPERFAMILY SSF56655 1 312 3.11E-110 T 11-10-2018 UP12_11030 7ac37a4434b66df392538e747680f730 102 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 2 98 2.4E-38 T 11-10-2018 IPR014211 Stage III sporulation protein AD UP12_11030 7ac37a4434b66df392538e747680f730 102 Pfam PF06686 Stage III sporulation protein AC/AD protein family 42 96 1.6E-19 T 11-10-2018 IPR025664 Stage III sporulation protein AC/AD family UP12_11355 a89e7d5c62956a917100c60da22b1ac7 120 Pfam PF06781 Cell division protein CrgA 70 117 2.5E-6 T 11-10-2018 IPR009619 Cell division protein CrgA UP12_10665 6f76bd9a268ab727faf1e3a9a015344f 235 Pfam PF03330 Lytic transglycolase 80 130 2.5E-6 T 11-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain UP12_10665 6f76bd9a268ab727faf1e3a9a015344f 235 Gene3D G3DSA:2.60.40.760 136 229 3.9E-31 T 11-10-2018 IPR036749 Expansin, cellulose-binding-like domain superfamily UP12_10665 6f76bd9a268ab727faf1e3a9a015344f 235 SUPERFAMILY SSF49590 139 209 3.92E-12 T 11-10-2018 IPR036749 Expansin, cellulose-binding-like domain superfamily UP12_10665 6f76bd9a268ab727faf1e3a9a015344f 235 Gene3D G3DSA:2.40.40.10 29 135 4.3E-26 T 11-10-2018 IPR036908 RlpA-like domain superfamily UP12_10665 6f76bd9a268ab727faf1e3a9a015344f 235 SUPERFAMILY SSF50685 25 140 1.92E-17 T 11-10-2018 IPR036908 RlpA-like domain superfamily UP12_16945 49de11d7c89ec180916adc51c4dd6aa5 177 Pfam PF02417 Chromate transporter 6 171 4.6E-36 T 11-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 UP12_05430 a61b8d878cbd261e5d52a2bd8bb87795 186 SUPERFAMILY SSF55729 9 174 9.72E-33 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_05430 a61b8d878cbd261e5d52a2bd8bb87795 186 Gene3D G3DSA:3.40.630.30 4 183 9.4E-35 T 11-10-2018 UP12_05430 a61b8d878cbd261e5d52a2bd8bb87795 186 Pfam PF13302 Acetyltransferase (GNAT) domain 11 149 8.1E-15 T 11-10-2018 IPR000182 GNAT domain UP12_19290 9d03f5ee1dc6764aef1a294933ff9455 666 SUPERFAMILY SSF52540 226 608 1.63E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_19290 9d03f5ee1dc6764aef1a294933ff9455 666 Gene3D G3DSA:3.40.50.300 247 611 3.3E-44 T 11-10-2018 UP12_19290 9d03f5ee1dc6764aef1a294933ff9455 666 Gene3D G3DSA:1.10.8.730 312 457 3.3E-44 T 11-10-2018 UP12_13315 c69fce5cd0e5e4d4db0c0341ff4371ad 70 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 11 65 3.8E-22 T 11-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 UP12_13315 c69fce5cd0e5e4d4db0c0341ff4371ad 70 Gene3D G3DSA:1.10.8.910 11 69 2.5E-30 T 11-10-2018 IPR038300 SASP, alpha/beta-type superfamily UP12_13315 c69fce5cd0e5e4d4db0c0341ff4371ad 70 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 44 58 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 UP12_13315 c69fce5cd0e5e4d4db0c0341ff4371ad 70 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 26 35 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 UP12_01500 465636d2a6deccf94b188c6348323df0 493 ProSitePatterns PS00571 Amidases signature. 149 180 - T 11-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 UP12_01500 465636d2a6deccf94b188c6348323df0 493 SUPERFAMILY SSF75304 3 481 5.76E-117 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_01500 465636d2a6deccf94b188c6348323df0 493 Gene3D G3DSA:3.90.1300.10 3 492 1.6E-145 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_01500 465636d2a6deccf94b188c6348323df0 493 Pfam PF01425 Amidase 27 473 2.3E-85 T 11-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 UP12_11995 263ca0f44f5de335ccbc8b8cc34d60d3 242 Gene3D G3DSA:3.40.50.300 1 241 1.5E-79 T 11-10-2018 UP12_11995 263ca0f44f5de335ccbc8b8cc34d60d3 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_11995 263ca0f44f5de335ccbc8b8cc34d60d3 242 SUPERFAMILY SSF52540 1 234 4.56E-81 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11995 263ca0f44f5de335ccbc8b8cc34d60d3 242 SMART SM00382 26 213 3.2E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_11995 263ca0f44f5de335ccbc8b8cc34d60d3 242 Pfam PF00005 ABC transporter 17 165 2.5E-38 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_11995 263ca0f44f5de335ccbc8b8cc34d60d3 242 PIRSF PIRSF039085 1 241 1.4E-115 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UP12_15980 367ecbdaacb9b32c42a50b3641089001 268 SUPERFAMILY SSF52540 5 255 8.54E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15980 367ecbdaacb9b32c42a50b3641089001 268 SMART SM00382 34 233 1.2E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15980 367ecbdaacb9b32c42a50b3641089001 268 TIGRFAM TIGR02770 nickel_nikD: nickel import ATP-binding protein NikD 24 259 4.9E-97 T 11-10-2018 IPR014138 Nickel import ATP-binding protein NikD GO:0005886|GO:0015413|GO:0015675|GO:0016151 UP12_15980 367ecbdaacb9b32c42a50b3641089001 268 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_15980 367ecbdaacb9b32c42a50b3641089001 268 Gene3D G3DSA:3.40.50.300 3 265 4.2E-80 T 11-10-2018 UP12_15980 367ecbdaacb9b32c42a50b3641089001 268 Pfam PF00005 ABC transporter 26 183 9.1E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_11700 175e0bb8d58431752b77b1fbef0930b7 83 Pfam PF13143 Protein of unknown function (DUF3986) 1 79 2.1E-13 T 11-10-2018 IPR025047 Protein of unknown function DUF3986 UP12_02270 755d3623c6023444cc8bd14601dc3885 337 SMART SM00797 24 323 2.8E-132 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B UP12_02270 755d3623c6023444cc8bd14601dc3885 337 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 306 5.2E-92 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B UP12_02270 755d3623c6023444cc8bd14601dc3885 337 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 331 2.2E-93 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B UP12_02270 755d3623c6023444cc8bd14601dc3885 337 SUPERFAMILY SSF50891 198 313 1.21E-8 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily UP12_02270 755d3623c6023444cc8bd14601dc3885 337 Gene3D G3DSA:2.40.100.10 196 335 6.3E-48 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily UP12_05260 d0932724baf5a7d7ec90a3d132bfe529 388 Pfam PF07690 Major Facilitator Superfamily 20 342 2.1E-17 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_05260 d0932724baf5a7d7ec90a3d132bfe529 388 ProSitePatterns PS00216 Sugar transport proteins signature 1. 70 86 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_05260 d0932724baf5a7d7ec90a3d132bfe529 388 SUPERFAMILY SSF103473 17 384 6.41E-32 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_05260 d0932724baf5a7d7ec90a3d132bfe529 388 Gene3D G3DSA:1.20.1250.20 16 385 2.4E-29 T 11-10-2018 UP12_10295 0279245a6a80055e8326d9fe6dde6483 60 ProDom PD052359 YPFB 1 57 1.0E-6 T 11-10-2018 IPR035281 Protein of unknown function DUF5359 UP12_10295 0279245a6a80055e8326d9fe6dde6483 60 Pfam PF17313 Family of unknown function (DUF5359) 1 56 2.0E-19 T 11-10-2018 IPR035281 Protein of unknown function DUF5359 UP12_01125 e54117ed89b92080d0eedf999a08a88e 63 Pfam PF13396 Phospholipase_D-nuclease N-terminal 15 60 6.1E-13 T 11-10-2018 IPR027379 Cardiolipin synthase N-terminal UP12_14140 0db01de04ce583ea4b2f3094445983f2 87 Pfam PF04688 SPP1 phage holin 4 82 1.4E-29 T 11-10-2018 IPR006479 Holin UP12_14140 0db01de04ce583ea4b2f3094445983f2 87 TIGRFAM TIGR01592 holin_SPP1: holin, SPP1 family 5 85 1.0E-30 T 11-10-2018 IPR006479 Holin UP12_14140 0db01de04ce583ea4b2f3094445983f2 87 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 4 87 3.0E-34 T 11-10-2018 IPR006479 Holin UP12_18640 050dce842ec063e746ecb8d96a541895 183 Pfam PF10400 Virulence activator alpha C-term 98 177 4.3E-13 T 11-10-2018 IPR018309 Transcription regulator PadR, C-terminal UP12_18640 050dce842ec063e746ecb8d96a541895 183 Pfam PF03551 Transcriptional regulator PadR-like family 11 84 2.5E-12 T 11-10-2018 IPR005149 Transcription regulator PadR, N-terminal UP12_18640 050dce842ec063e746ecb8d96a541895 183 SUPERFAMILY SSF46785 7 180 1.19E-36 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18640 050dce842ec063e746ecb8d96a541895 183 Gene3D G3DSA:1.10.10.10 6 93 4.0E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01325 bdcd4e6a9fa002ccf6d3c55ea914a0c2 255 Pfam PF13673 Acetyltransferase (GNAT) domain 164 253 2.5E-8 T 11-10-2018 IPR000182 GNAT domain UP12_01325 bdcd4e6a9fa002ccf6d3c55ea914a0c2 255 Gene3D G3DSA:3.40.630.30 29 255 2.9E-22 T 11-10-2018 UP12_01325 bdcd4e6a9fa002ccf6d3c55ea914a0c2 255 SUPERFAMILY SSF55729 78 253 1.01E-17 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_05645 85d043124faf7a7794f319167e0f931c 413 PIRSF PIRSF000447 1 413 2.1E-190 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UP12_05645 85d043124faf7a7794f319167e0f931c 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 2.9E-61 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal UP12_05645 85d043124faf7a7794f319167e0f931c 413 SMART SM00825 Beta-ketoacyl synthase 6 413 2.6E-17 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain UP12_05645 85d043124faf7a7794f319167e0f931c 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 3.6E-202 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UP12_05645 85d043124faf7a7794f319167e0f931c 413 SUPERFAMILY SSF53901 4 251 1.27E-74 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_05645 85d043124faf7a7794f319167e0f931c 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site UP12_05645 85d043124faf7a7794f319167e0f931c 413 Gene3D G3DSA:3.40.47.10 256 400 2.3E-58 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_05645 85d043124faf7a7794f319167e0f931c 413 SUPERFAMILY SSF53901 214 411 5.49E-78 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_05645 85d043124faf7a7794f319167e0f931c 413 Gene3D G3DSA:3.40.47.10 1 254 1.2E-106 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_05645 85d043124faf7a7794f319167e0f931c 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 1.7E-41 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal UP12_02285 8be1648f25dc5166238e69b625e57a40 210 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 197 9.9E-25 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain UP12_02285 8be1648f25dc5166238e69b625e57a40 210 Gene3D G3DSA:3.40.50.1110 4 207 3.3E-31 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_02285 8be1648f25dc5166238e69b625e57a40 210 SUPERFAMILY SSF52266 4 206 5.78E-36 T 11-10-2018 UP12_16915 e255ca34b113c5173a0c2d8e99431c7c 200 SMART SM00903 15 172 1.4E-24 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UP12_16915 e255ca34b113c5173a0c2d8e99431c7c 200 Pfam PF01613 Flavin reductase like domain 18 162 2.2E-17 T 11-10-2018 IPR002563 Flavin reductase like domain GO:0010181 UP12_16915 e255ca34b113c5173a0c2d8e99431c7c 200 Gene3D G3DSA:2.30.110.10 1 200 5.9E-61 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UP12_16915 e255ca34b113c5173a0c2d8e99431c7c 200 SUPERFAMILY SSF50475 2 191 2.94E-39 T 11-10-2018 UP12_13100 b0ca26f9671f86f239f4cb83c51c1965 129 Pfam PF04186 FxsA cytoplasmic membrane protein 7 115 9.5E-35 T 11-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 UP12_03025 73efbd7e1b7b983dafe1463a775cbea2 184 SUPERFAMILY SSF47413 4 72 1.39E-18 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_03025 73efbd7e1b7b983dafe1463a775cbea2 184 Pfam PF01381 Helix-turn-helix 13 66 3.5E-17 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_03025 73efbd7e1b7b983dafe1463a775cbea2 184 SMART SM00530 11 66 2.2E-16 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_03025 73efbd7e1b7b983dafe1463a775cbea2 184 SUPERFAMILY SSF51182 51 183 2.97E-27 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_03025 73efbd7e1b7b983dafe1463a775cbea2 184 Pfam PF07883 Cupin domain 110 178 8.2E-12 T 11-10-2018 IPR013096 Cupin 2, conserved barrel UP12_03025 73efbd7e1b7b983dafe1463a775cbea2 184 Gene3D G3DSA:1.10.260.40 2 78 2.7E-20 T 11-10-2018 UP12_03025 73efbd7e1b7b983dafe1463a775cbea2 184 Gene3D G3DSA:2.60.120.10 91 184 8.3E-29 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_11100 d4952dfb2269d631c5ac3860b4d82032 126 SMART SM00450 29 124 2.5E-31 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_11100 d4952dfb2269d631c5ac3860b4d82032 126 Pfam PF00581 Rhodanese-like domain 41 118 1.4E-18 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_11100 d4952dfb2269d631c5ac3860b4d82032 126 Gene3D G3DSA:3.40.250.10 31 126 3.6E-29 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_11100 d4952dfb2269d631c5ac3860b4d82032 126 SUPERFAMILY SSF52821 27 119 2.23E-33 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_00565 65d42b37bd2c402eace5a95dd20fbd83 154 PIRSF PIRSF010607 1 154 5.8E-67 T 11-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 UP12_00565 65d42b37bd2c402eace5a95dd20fbd83 154 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 151 2.9E-58 T 11-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 UP12_00565 65d42b37bd2c402eace5a95dd20fbd83 154 Gene3D G3DSA:1.10.1200.150 74 154 9.0E-28 T 11-10-2018 UP12_00565 65d42b37bd2c402eace5a95dd20fbd83 154 Gene3D G3DSA:1.10.10.1240 3 73 5.4E-36 T 11-10-2018 UP12_16010 ba47f3e491549aeaee2c18ef33093a2a 198 Pfam PF02397 Bacterial sugar transferase 3 177 9.6E-63 T 11-10-2018 IPR003362 Bacterial sugar transferase UP12_18650 e9c6d8b82b8c8632d4102fbf881a7c44 207 Gene3D G3DSA:3.90.79.10 2 202 1.7E-54 T 11-10-2018 UP12_18650 e9c6d8b82b8c8632d4102fbf881a7c44 207 SUPERFAMILY SSF55811 26 196 1.27E-30 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UP12_18650 e9c6d8b82b8c8632d4102fbf881a7c44 207 Pfam PF00293 NUDIX domain 25 138 3.0E-15 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UP12_18650 e9c6d8b82b8c8632d4102fbf881a7c44 207 PRINTS PR00502 NUDIX hydrolase family signature 71 86 3.3E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_18650 e9c6d8b82b8c8632d4102fbf881a7c44 207 PRINTS PR00502 NUDIX hydrolase family signature 57 71 3.3E-5 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 UP12_18650 e9c6d8b82b8c8632d4102fbf881a7c44 207 ProSitePatterns PS00893 Nudix box signature. 62 83 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UP12_11520 f36cc53c92e35259244aab91a13d64e2 437 SUPERFAMILY SSF52096 14 167 4.98E-28 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_11520 f36cc53c92e35259244aab91a13d64e2 437 Pfam PF01972 Serine dehydrogenase proteinase 62 125 2.4E-9 T 11-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 UP12_11520 f36cc53c92e35259244aab91a13d64e2 437 Gene3D G3DSA:3.90.226.10 25 235 2.7E-49 T 11-10-2018 UP12_11520 f36cc53c92e35259244aab91a13d64e2 437 Gene3D G3DSA:2.40.50.140 370 437 5.6E-7 T 11-10-2018 UP12_11520 f36cc53c92e35259244aab91a13d64e2 437 Pfam PF01957 NfeD-like C-terminal, partner-binding 289 436 3.9E-18 T 11-10-2018 IPR002810 NfeD-like, C-terminal domain UP12_08815 5d348eca16a291bea6d03bd8f2953cf2 392 Gene3D G3DSA:1.20.1250.20 7 192 4.4E-12 T 11-10-2018 UP12_08815 5d348eca16a291bea6d03bd8f2953cf2 392 Gene3D G3DSA:1.20.1250.20 200 387 2.3E-22 T 11-10-2018 UP12_08815 5d348eca16a291bea6d03bd8f2953cf2 392 SUPERFAMILY SSF103473 6 384 1.15E-38 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_08815 5d348eca16a291bea6d03bd8f2953cf2 392 Pfam PF07690 Major Facilitator Superfamily 134 327 2.2E-14 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_18520 87cf7261b8d605ffc9b081c7664d99da 412 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 195 402 1.1E-23 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_18520 87cf7261b8d605ffc9b081c7664d99da 412 SUPERFAMILY SSF160964 107 164 5.23E-8 T 11-10-2018 UP12_18520 87cf7261b8d605ffc9b081c7664d99da 412 Gene3D G3DSA:1.10.3720.10 155 412 5.7E-68 T 11-10-2018 IPR035906 MetI-like superfamily UP12_18520 87cf7261b8d605ffc9b081c7664d99da 412 SUPERFAMILY SSF161098 160 396 1.83E-57 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 2.5E-273 T 11-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 Gene3D G3DSA:3.40.605.10 9 511 1.8E-191 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 Gene3D G3DSA:3.40.309.10 290 480 1.8E-191 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 Pfam PF00171 Aldehyde dehydrogenase family 50 511 1.0E-154 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 67.455 T 11-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 UP12_01905 c4ceb109564f1b7bfd4853270dcc0142 515 SUPERFAMILY SSF53720 4 511 6.68E-157 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 UP12_09540 ab5e1739dd2c23ae274067302a4ac3dc 292 Gene3D G3DSA:3.40.50.300 38 202 1.2E-33 T 11-10-2018 UP12_09540 ab5e1739dd2c23ae274067302a4ac3dc 292 Pfam PF07728 AAA domain (dynein-related subfamily) 55 192 5.2E-28 T 11-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 UP12_09540 ab5e1739dd2c23ae274067302a4ac3dc 292 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 128 146 3.7E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_09540 ab5e1739dd2c23ae274067302a4ac3dc 292 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 56 74 3.7E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 UP12_09540 ab5e1739dd2c23ae274067302a4ac3dc 292 SMART SM00382 52 201 1.1E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_09540 ab5e1739dd2c23ae274067302a4ac3dc 292 SUPERFAMILY SSF52540 43 273 1.88E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05930 aab2ceaf5374accf115fa4f591dd0763 392 SUPERFAMILY SSF53383 23 383 1.65E-110 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_05930 aab2ceaf5374accf115fa4f591dd0763 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 381 9.8E-148 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_05930 aab2ceaf5374accf115fa4f591dd0763 392 PIRSF PIRSF001434 1 385 2.3E-145 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_05930 aab2ceaf5374accf115fa4f591dd0763 392 Gene3D G3DSA:3.90.1150.10 250 384 2.0E-47 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_05930 aab2ceaf5374accf115fa4f591dd0763 392 Gene3D G3DSA:3.40.640.10 1 249 5.5E-88 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_05930 aab2ceaf5374accf115fa4f591dd0763 392 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 192 206 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 UP12_11775 69308c6f628ede10eeabed9e099accae 185 Pfam PF01380 SIS domain 36 155 1.0E-17 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_11775 69308c6f628ede10eeabed9e099accae 185 Gene3D G3DSA:3.40.50.10490 1 185 4.5E-54 T 11-10-2018 UP12_11775 69308c6f628ede10eeabed9e099accae 185 SUPERFAMILY SSF53697 5 184 9.91E-38 T 11-10-2018 UP12_11775 69308c6f628ede10eeabed9e099accae 185 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 8 185 1.6E-68 T 11-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 UP12_17905 0230c1b942cca9b707ac5b989b39eedb 113 Pfam PF03788 LrgA family 10 99 3.3E-24 T 11-10-2018 IPR005538 LrgA/CidA family GO:0016021 UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 Pfam PF00425 chorismate binding enzyme 201 454 1.3E-98 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 SUPERFAMILY SSF56322 16 464 7.72E-147 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 PRINTS PR00095 Anthranilate synthase component I signature 302 315 8.6E-18 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 PRINTS PR00095 Anthranilate synthase component I signature 316 329 8.6E-18 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 PRINTS PR00095 Anthranilate synthase component I signature 411 425 8.6E-18 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 PRINTS PR00095 Anthranilate synthase component I signature 396 410 8.6E-18 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 Pfam PF04715 Anthranilate synthase component I, N terminal region 16 150 7.0E-31 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 UP12_00445 065e765acb62cea94fd680e2a3b2bc79 472 Gene3D G3DSA:3.60.120.10 2 470 4.5E-162 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_11365 06a56a7533c1412c7410104a5d627d54 305 Gene3D G3DSA:3.30.420.40 106 297 2.4E-48 T 11-10-2018 UP12_11365 06a56a7533c1412c7410104a5d627d54 305 Pfam PF00480 ROK family 7 288 2.7E-47 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 UP12_11365 06a56a7533c1412c7410104a5d627d54 305 SUPERFAMILY SSF53067 1 293 2.03E-51 T 11-10-2018 UP12_11365 06a56a7533c1412c7410104a5d627d54 305 Gene3D G3DSA:3.30.420.40 2 105 3.7E-21 T 11-10-2018 UP12_07070 548b45a82540e632880f8e1a419fa370 447 Gene3D G3DSA:4.10.320.10 130 183 3.8E-20 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_07070 548b45a82540e632880f8e1a419fa370 447 Gene3D G3DSA:3.30.559.10 199 444 1.4E-90 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 UP12_07070 548b45a82540e632880f8e1a419fa370 447 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UP12_07070 548b45a82540e632880f8e1a419fa370 447 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 217 445 2.5E-89 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 UP12_07070 548b45a82540e632880f8e1a419fa370 447 Pfam PF02817 e3 binding domain 141 175 3.4E-14 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 UP12_07070 548b45a82540e632880f8e1a419fa370 447 SUPERFAMILY SSF51230 3 92 6.28E-25 T 11-10-2018 IPR011053 Single hybrid motif UP12_07070 548b45a82540e632880f8e1a419fa370 447 SUPERFAMILY SSF52777 207 445 9.78E-89 T 11-10-2018 UP12_07070 548b45a82540e632880f8e1a419fa370 447 Gene3D G3DSA:2.40.50.100 2 81 2.1E-25 T 11-10-2018 UP12_07070 548b45a82540e632880f8e1a419fa370 447 SUPERFAMILY SSF47005 135 181 8.11E-13 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 UP12_07070 548b45a82540e632880f8e1a419fa370 447 Pfam PF00364 Biotin-requiring enzyme 4 75 2.2E-22 T 11-10-2018 IPR000089 Biotin/lipoyl attachment UP12_00470 461f348b4ea3c4f5173d20c746269bf2 167 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 134 5.5E-50 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UP12_00470 461f348b4ea3c4f5173d20c746269bf2 167 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UP12_00470 461f348b4ea3c4f5173d20c746269bf2 167 Gene3D G3DSA:3.30.70.560 1 152 2.3E-56 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UP12_00470 461f348b4ea3c4f5173d20c746269bf2 167 SUPERFAMILY SSF55083 3 136 5.36E-52 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UP12_00470 461f348b4ea3c4f5173d20c746269bf2 167 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 134 2.1E-39 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 UP12_15385 d056fe2b83a85c3436ebe3a6b9db668c 406 Gene3D G3DSA:3.40.640.10 34 294 1.4E-185 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_15385 d056fe2b83a85c3436ebe3a6b9db668c 406 SUPERFAMILY SSF53383 2 398 2.42E-136 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_15385 d056fe2b83a85c3436ebe3a6b9db668c 406 Gene3D G3DSA:3.90.1150.10 6 395 1.4E-185 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_15385 d056fe2b83a85c3436ebe3a6b9db668c 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site UP12_15385 d056fe2b83a85c3436ebe3a6b9db668c 406 Pfam PF00266 Aminotransferase class-V 23 391 4.4E-165 T 11-10-2018 IPR000192 Aminotransferase class V domain UP12_15385 d056fe2b83a85c3436ebe3a6b9db668c 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 402 4.2E-192 T 11-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 UP12_15385 d056fe2b83a85c3436ebe3a6b9db668c 406 PIRSF PIRSF005572 20 405 3.9E-52 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 UP12_09405 f9b8657962fd623293457d50c589e2d2 293 SUPERFAMILY SSF55961 3 158 3.77E-8 T 11-10-2018 UP12_15140 fba173206cec04572023e59c98f72063 120 Gene3D G3DSA:2.60.300.12 4 112 1.2E-37 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UP12_15140 fba173206cec04572023e59c98f72063 120 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 91 108 - T 11-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 UP12_15140 fba173206cec04572023e59c98f72063 120 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 5 109 6.2E-39 T 11-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 UP12_15140 fba173206cec04572023e59c98f72063 120 Pfam PF01521 Iron-sulphur cluster biosynthesis 5 105 1.3E-21 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 UP12_15140 fba173206cec04572023e59c98f72063 120 SUPERFAMILY SSF89360 4 98 1.35E-30 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 UP12_09905 480f59fc22964ba4830a9be066e354c9 366 Gene3D G3DSA:3.40.47.10 1 212 7.2E-63 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_09905 480f59fc22964ba4830a9be066e354c9 366 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 2 203 5.6E-23 T 11-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal UP12_09905 480f59fc22964ba4830a9be066e354c9 366 Gene3D G3DSA:3.40.47.10 218 362 1.8E-39 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_09905 480f59fc22964ba4830a9be066e354c9 366 SUPERFAMILY SSF53901 219 361 6.33E-38 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_09905 480f59fc22964ba4830a9be066e354c9 366 PIRSF PIRSF000451 1 364 7.6E-125 T 11-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 UP12_09905 480f59fc22964ba4830a9be066e354c9 366 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 228 360 1.2E-18 T 11-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal UP12_09905 480f59fc22964ba4830a9be066e354c9 366 SUPERFAMILY SSF53901 1 207 4.13E-47 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_09600 41b9c12fb259819b92579d7f7f96fa98 205 Gene3D G3DSA:3.40.109.10 1 205 2.4E-51 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_09600 41b9c12fb259819b92579d7f7f96fa98 205 SUPERFAMILY SSF55469 6 202 4.97E-50 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 UP12_09600 41b9c12fb259819b92579d7f7f96fa98 205 Pfam PF00881 Nitroreductase family 11 185 5.5E-30 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 UP12_01805 c2ac2712873ba1d1a7e5d0f70e26147c 281 Pfam PF00285 Citrate synthase, C-terminal domain 17 66 1.6E-6 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_01805 c2ac2712873ba1d1a7e5d0f70e26147c 281 Pfam PF00285 Citrate synthase, C-terminal domain 59 253 1.2E-28 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 UP12_01805 c2ac2712873ba1d1a7e5d0f70e26147c 281 Gene3D G3DSA:1.10.580.10 64 247 2.3E-29 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UP12_01805 c2ac2712873ba1d1a7e5d0f70e26147c 281 Gene3D G3DSA:1.10.230.10 113 221 2.3E-29 T 11-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain UP12_01805 c2ac2712873ba1d1a7e5d0f70e26147c 281 Gene3D G3DSA:1.10.580.10 15 63 1.3E-6 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 UP12_01805 c2ac2712873ba1d1a7e5d0f70e26147c 281 SUPERFAMILY SSF48256 13 251 8.64E-49 T 11-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 UP12_02525 a12e0384acfbe65f6f4e88e078469aa8 121 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 120 5.0E-42 T 11-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UP12_02525 a12e0384acfbe65f6f4e88e078469aa8 121 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 119 1.0E-35 T 11-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UP12_02525 a12e0384acfbe65f6f4e88e078469aa8 121 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 118 1.1E-30 T 11-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UP12_02525 a12e0384acfbe65f6f4e88e078469aa8 121 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 118 24.245 T 11-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 UP12_02525 a12e0384acfbe65f6f4e88e078469aa8 121 SUPERFAMILY SSF56214 1 117 1.23E-33 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_02525 a12e0384acfbe65f6f4e88e078469aa8 121 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 113 6.3E-23 T 11-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_02525 a12e0384acfbe65f6f4e88e078469aa8 121 Gene3D G3DSA:3.90.470.20 1 121 8.8E-39 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 UP12_18415 ac8f85f5de4222f598ae9531920834fb 365 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 5 114 4.9E-7 T 11-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 UP12_18415 ac8f85f5de4222f598ae9531920834fb 365 Gene3D G3DSA:3.40.50.720 1 117 3.2E-13 T 11-10-2018 UP12_18415 ac8f85f5de4222f598ae9531920834fb 365 SUPERFAMILY SSF51735 4 134 6.2E-9 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_18415 ac8f85f5de4222f598ae9531920834fb 365 Gene3D G3DSA:3.30.360.10 127 306 1.2E-18 T 11-10-2018 UP12_11535 aef985140c672a87a599a6a9b543049d 309 Pfam PF02690 Na+/Pi-cotransporter 13 146 6.3E-34 T 11-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 UP12_11535 aef985140c672a87a599a6a9b543049d 309 Pfam PF02690 Na+/Pi-cotransporter 159 259 6.0E-16 T 11-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 UP12_11535 aef985140c672a87a599a6a9b543049d 309 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 306 6.0E-103 T 11-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 UP12_11110 15375975ca564e99669c76b955189e05 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 50.072 T 11-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 UP12_11110 15375975ca564e99669c76b955189e05 448 SUPERFAMILY SSF53383 3 443 2.39E-121 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_11110 15375975ca564e99669c76b955189e05 448 PIRSF PIRSF006815 3 447 1.4E-187 T 11-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 UP12_11110 15375975ca564e99669c76b955189e05 448 Gene3D G3DSA:3.90.1150.10 73 443 8.2E-165 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 UP12_11110 15375975ca564e99669c76b955189e05 448 Pfam PF02347 Glycine cleavage system P-protein 3 442 4.2E-168 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 UP12_11110 15375975ca564e99669c76b955189e05 448 Gene3D G3DSA:3.40.640.10 84 349 8.2E-165 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_16305 10b39b098b23d1f2d6d2817de1f43756 172 Gene3D G3DSA:2.160.10.10 16 171 1.2E-29 T 11-10-2018 UP12_16305 10b39b098b23d1f2d6d2817de1f43756 172 SUPERFAMILY SSF51161 26 158 1.52E-33 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_16305 10b39b098b23d1f2d6d2817de1f43756 172 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 139 7.8E-11 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_10410 db6d5ca7ce273e651750afddf8bb52a2 559 Pfam PF05140 ResB-like family 66 429 1.1E-72 T 11-10-2018 IPR007816 ResB-like domain UP12_10410 db6d5ca7ce273e651750afddf8bb52a2 559 Pfam PF05140 ResB-like family 442 521 3.9E-18 T 11-10-2018 IPR007816 ResB-like domain UP12_06340 4f62785b3368dc88e5b2a9bbdd23c350 162 Pfam PF06695 Putative small multi-drug export protein 20 135 1.5E-14 T 11-10-2018 IPR009577 Putative small multi-drug export UP12_12930 7358f5e743adddff9e1b5ea27b660c6d 73 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 21.691 T 11-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 UP12_12930 7358f5e743adddff9e1b5ea27b660c6d 73 Pfam PF14098 Small, acid-soluble spore protein I 3 67 5.9E-29 T 11-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 UP12_12930 7358f5e743adddff9e1b5ea27b660c6d 73 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 1.4E-31 T 11-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 UP12_07375 ae72265032dfb82e19866b483d499904 366 Pfam PF01098 Cell cycle protein 12 365 3.0E-130 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07375 ae72265032dfb82e19866b483d499904 366 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 9 362 4.6E-185 T 11-10-2018 IPR013438 Sporulation stage V, protein E UP12_07375 ae72265032dfb82e19866b483d499904 366 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 9 363 2.1E-132 T 11-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07375 ae72265032dfb82e19866b483d499904 366 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 322 346 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_16330 745599802ddaec609c4f67341ad2798c 396 SUPERFAMILY SSF51556 58 359 7.4E-92 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_16330 745599802ddaec609c4f67341ad2798c 396 PIRSF PIRSF038994 3 392 8.0E-131 T 11-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 UP12_16330 745599802ddaec609c4f67341ad2798c 396 Gene3D G3DSA:2.30.40.10 12 387 5.2E-141 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_16330 745599802ddaec609c4f67341ad2798c 396 SUPERFAMILY SSF51338 5 393 5.41E-19 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 UP12_16330 745599802ddaec609c4f67341ad2798c 396 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 385 1.1E-127 T 11-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 UP12_16330 745599802ddaec609c4f67341ad2798c 396 Gene3D G3DSA:3.20.20.140 58 359 5.2E-141 T 11-10-2018 UP12_16330 745599802ddaec609c4f67341ad2798c 396 Pfam PF01979 Amidohydrolase family 54 388 4.4E-28 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 Pfam PF03466 LysR substrate binding domain 89 285 3.2E-37 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 Gene3D G3DSA:3.40.190.290 90 286 3.6E-45 T 11-10-2018 UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 SUPERFAMILY SSF53850 89 286 1.36E-34 T 11-10-2018 UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 SUPERFAMILY SSF46785 4 110 1.62E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.1E-19 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 4.2E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 4.2E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 4.2E-7 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_18735 089eb28c095d0538da2e69f3992a64c5 286 Gene3D G3DSA:1.10.10.10 2 84 2.2E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 SUPERFAMILY SSF46894 131 232 1.62E-25 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 Gene3D G3DSA:3.40.50.2300 2 132 2.6E-33 T 11-10-2018 UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 Gene3D G3DSA:1.10.10.10 133 240 1.6E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 SMART SM00862 155 231 7.0E-22 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 231 8.3E-23 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 SUPERFAMILY SSF52172 3 131 1.42E-35 T 11-10-2018 IPR011006 CheY-like superfamily UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 SMART SM00448 4 115 1.7E-38 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_15620 c2c700551f146dbfb024ff9d44f114f8 240 Pfam PF00072 Response regulator receiver domain 6 116 1.1E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_02400 68066340dbe11ce51fda71ca567393f3 159 Pfam PF10004 Uncharacterized protein conserved in bacteria (DUF2247) 6 154 3.7E-36 T 11-10-2018 IPR016630 Uncharacterised conserved protein UCP015278 UP12_03330 2d044ca3f92c0eefa72dcb7456ed0765 66 Pfam PF14044 NETI protein 9 64 3.5E-28 T 11-10-2018 IPR025930 NETI protein UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 38.013 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 SUPERFAMILY SSF52540 8 142 1.68E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 Gene3D G3DSA:3.30.60.20 142 193 7.2E-27 T 11-10-2018 UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 Gene3D G3DSA:3.40.50.300 1 141 1.1E-58 T 11-10-2018 UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 PIRSF PIRSF035805 5 197 1.7E-65 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 11-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 Pfam PF00265 Thymidine kinase 8 187 1.2E-57 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 UP12_17295 30bfee9e4c473dfc362e0acf3929d8f2 200 SUPERFAMILY SSF57716 142 193 9.27E-17 T 11-10-2018 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 Pfam PF01235 Sodium:alanine symporter family 48 444 1.8E-159 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 PRINTS PR00175 Sodium/alanine symporter signature 296 314 1.0E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 PRINTS PR00175 Sodium/alanine symporter signature 341 363 1.0E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 PRINTS PR00175 Sodium/alanine symporter signature 205 224 1.0E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 PRINTS PR00175 Sodium/alanine symporter signature 177 195 1.0E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 PRINTS PR00175 Sodium/alanine symporter signature 401 421 1.0E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 PRINTS PR00175 Sodium/alanine symporter signature 87 109 1.0E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 87 102 - T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_01545 8d48009b0116ec61863edaf791aeb83f 471 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 432 2.9E-153 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 UP12_12920 9af7ccdf6ff93c7cd59ef47b37d91d7f 344 SUPERFAMILY SSF55681 93 342 7.74E-83 T 11-10-2018 UP12_12920 9af7ccdf6ff93c7cd59ef47b37d91d7f 344 SUPERFAMILY SSF46589 14 99 5.23E-21 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 UP12_12920 9af7ccdf6ff93c7cd59ef47b37d91d7f 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 48.889 T 11-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 UP12_12920 9af7ccdf6ff93c7cd59ef47b37d91d7f 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 1.9E-108 T 11-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 UP12_12920 9af7ccdf6ff93c7cd59ef47b37d91d7f 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 1.6E-115 T 11-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 UP12_12920 9af7ccdf6ff93c7cd59ef47b37d91d7f 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 8.3E-25 T 11-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 UP12_12920 9af7ccdf6ff93c7cd59ef47b37d91d7f 344 Gene3D G3DSA:3.30.930.10 9 343 1.4E-126 T 11-10-2018 UP12_07230 cabbfa20952d9aa3da6b704f9358902b 292 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 26 275 3.6E-63 T 11-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related UP12_07230 cabbfa20952d9aa3da6b704f9358902b 292 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 3 277 8.6E-123 T 11-10-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG UP12_11210 49fd4f9253c45a46f300de089e7534ff 126 SUPERFAMILY SSF52833 3 115 1.19E-34 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_11210 49fd4f9253c45a46f300de089e7534ff 126 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 116 5.7E-41 T 11-10-2018 IPR006504 Transcriptional regulator Spx/MgsR UP12_11210 49fd4f9253c45a46f300de089e7534ff 126 Pfam PF03960 ArsC family 7 112 3.5E-19 T 11-10-2018 IPR006660 Arsenate reductase-like UP12_11210 49fd4f9253c45a46f300de089e7534ff 126 Gene3D G3DSA:3.40.30.10 4 125 9.5E-38 T 11-10-2018 UP12_00430 af8003324c9130e8fd3e65aecd347e4d 291 PIRSF PIRSF005261 1 289 8.4E-77 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 UP12_00430 af8003324c9130e8fd3e65aecd347e4d 291 Pfam PF01430 Hsp33 protein 2 278 2.7E-89 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 UP12_00430 af8003324c9130e8fd3e65aecd347e4d 291 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 289 41.388 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 UP12_00430 af8003324c9130e8fd3e65aecd347e4d 291 SUPERFAMILY SSF118352 230 288 3.27E-21 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 UP12_00430 af8003324c9130e8fd3e65aecd347e4d 291 Gene3D G3DSA:3.55.30.10 1 234 6.1E-97 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 UP12_00430 af8003324c9130e8fd3e65aecd347e4d 291 Gene3D G3DSA:3.90.1280.10 235 291 2.3E-23 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 UP12_00430 af8003324c9130e8fd3e65aecd347e4d 291 SUPERFAMILY SSF64397 1 239 4.45E-77 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 Gene3D G3DSA:3.40.430.10 138 360 9.8E-66 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 147 359 1.3E-60 T 11-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 356 4.5E-121 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 51 89 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 Gene3D G3DSA:3.40.140.10 1 136 4.1E-46 T 11-10-2018 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 SUPERFAMILY SSF53927 4 145 2.63E-45 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 Pfam PF01872 RibD C-terminal domain 148 337 9.3E-51 T 11-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 PIRSF PIRSF006769 1 361 6.8E-129 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 101 2.1E-21 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain UP12_03850 d844ab0ad2e433f759e7b396587fbb6e 361 SUPERFAMILY SSF53597 146 357 9.1E-51 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_15825 09cf02aebcd21bc0170418d0b80ea2f3 76 SMART SM00530 11 66 1.1E-9 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_15825 09cf02aebcd21bc0170418d0b80ea2f3 76 Pfam PF01381 Helix-turn-helix 13 66 1.9E-12 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_15825 09cf02aebcd21bc0170418d0b80ea2f3 76 Gene3D G3DSA:1.10.260.40 10 76 1.8E-9 T 11-10-2018 UP12_15825 09cf02aebcd21bc0170418d0b80ea2f3 76 SUPERFAMILY SSF47413 11 72 1.18E-11 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_09660 5781fe8563f9238106e8f9a0728321b1 93 Pfam PF14122 YokU-like protein, putative antitoxin 3 89 5.4E-43 T 11-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU UP12_09660 5781fe8563f9238106e8f9a0728321b1 93 TIGRFAM TIGR03829 YokU_near_AblA: uncharacterized protein, YokU family 3 91 6.5E-50 T 11-10-2018 IPR022451 Conserved hypothetical protein CHP03829, YokU UP12_09660 5781fe8563f9238106e8f9a0728321b1 93 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 4 51 9.5E-12 T 11-10-2018 IPR022453 Zinc finger, MqsA-type UP12_17790 c6f8d3ec2f617d9ab120c1fdde8bd2f6 403 Pfam PF01098 Cell cycle protein 11 394 3.0E-93 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_15060 32f955f8b9c8f7e3c4a2734ae7a001db 437 Pfam PF10140 WXG100 protein secretion system (Wss), protein YukC 28 385 6.2E-133 T 11-10-2018 IPR018778 Type VII secretion system EssB UP12_15060 32f955f8b9c8f7e3c4a2734ae7a001db 437 Gene3D G3DSA:1.10.510.10 1 218 1.6E-78 T 11-10-2018 UP12_15060 32f955f8b9c8f7e3c4a2734ae7a001db 437 TIGRFAM TIGR03926 T7_EssB: type VII secretion protein EssB 8 385 5.3E-145 T 11-10-2018 IPR018778 Type VII secretion system EssB UP12_15060 32f955f8b9c8f7e3c4a2734ae7a001db 437 Gene3D G3DSA:1.25.40.680 241 403 3.4E-43 T 11-10-2018 UP12_03480 81bdc4beb871b6eb9800c3f6dbaacc44 395 PIRSF PIRSF012509 1 395 1.5E-152 T 11-10-2018 IPR011426 CamS sex pheromone cAM373 UP12_03480 81bdc4beb871b6eb9800c3f6dbaacc44 395 Gene3D G3DSA:3.10.570.10 55 395 2.8E-131 T 11-10-2018 UP12_03480 81bdc4beb871b6eb9800c3f6dbaacc44 395 Pfam PF07537 CamS sex pheromone cAM373 precursor 58 388 4.1E-124 T 11-10-2018 IPR011426 CamS sex pheromone cAM373 UP12_14205 55b98f1b3509cbb374a192d9aa7467e0 149 Pfam PF08890 Phage XkdN-like tail assembly chaperone protein, TAC 13 148 2.7E-37 T 11-10-2018 IPR014986 Clostridium phage phiCD119, XkdN UP12_14205 55b98f1b3509cbb374a192d9aa7467e0 149 Gene3D G3DSA:3.30.2220.30 17 137 4.4E-48 T 11-10-2018 IPR038559 Clostridium phage phiCD119, XkdN superfamily UP12_09530 9823990ccc3f3cba085808915e5e399c 944 SUPERFAMILY SSF52518 150 534 2.03E-73 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_09530 9823990ccc3f3cba085808915e5e399c 944 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 16 939 0.0 T 11-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Gene3D G3DSA:3.40.50.970 153 536 7.6E-137 T 11-10-2018 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Hamap MF_01169 2-oxoglutarate dehydrogenase E1 component [odhA]. 2 942 23.487 T 11-10-2018 IPR023784 2-oxoglutarate dehydrogenase E1 component, bacterial KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Gene3D G3DSA:3.40.50.12470 553 813 4.4E-152 T 11-10-2018 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 17 50 1.8E-7 T 11-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 796 939 2.1E-39 T 11-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Pfam PF02779 Transketolase, pyrimidine binding domain 594 791 4.5E-58 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Gene3D G3DSA:3.40.50.11610 731 938 4.4E-152 T 11-10-2018 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 PIRSF PIRSF000157 1 942 0.0 T 11-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 SMART SM00861 595 791 7.4E-41 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain UP12_09530 9823990ccc3f3cba085808915e5e399c 944 Pfam PF00676 Dehydrogenase E1 component 220 533 9.4E-90 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UP12_09530 9823990ccc3f3cba085808915e5e399c 944 SUPERFAMILY SSF52518 577 797 7.65E-42 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_08285 27c9a90b9f43027cc73c6b2ccde84b3e 193 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 191 3.1E-70 T 11-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 UP12_08285 27c9a90b9f43027cc73c6b2ccde84b3e 193 PIRSF PIRSF000847 1 193 1.0E-54 T 11-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 UP12_08285 27c9a90b9f43027cc73c6b2ccde84b3e 193 Gene3D G3DSA:1.20.120.1760 4 184 1.7E-10 T 11-10-2018 UP12_08285 27c9a90b9f43027cc73c6b2ccde84b3e 193 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UP12_08285 27c9a90b9f43027cc73c6b2ccde84b3e 193 Pfam PF01066 CDP-alcohol phosphatidyltransferase 3 82 7.2E-18 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 UP12_18600 b83bee854c26a6382953068816a7db01 248 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_18600 b83bee854c26a6382953068816a7db01 248 SUPERFAMILY SSF52540 7 223 4.85E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_18600 b83bee854c26a6382953068816a7db01 248 Pfam PF00005 ABC transporter 20 169 7.7E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_18600 b83bee854c26a6382953068816a7db01 248 Gene3D G3DSA:3.40.50.300 1 222 3.8E-60 T 11-10-2018 UP12_18600 b83bee854c26a6382953068816a7db01 248 SMART SM00382 29 217 7.4E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 SMART SM00028 20 53 15.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 SMART SM00028 54 87 120.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 SMART SM00028 152 185 180.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 SMART SM00028 186 219 2.0E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 Gene3D G3DSA:1.25.40.10 6 136 1.2E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 SUPERFAMILY SSF48452 222 320 7.59E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 Pfam PF14559 Tetratricopeptide repeat 162 226 3.4E-10 T 11-10-2018 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 SUPERFAMILY SSF48452 20 238 7.21E-21 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_16240 f26984d2601ab639991b317af5d0cd9b 485 Gene3D G3DSA:1.25.40.10 145 326 2.9E-20 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_17320 127891db19d08dda0d19efbd9af98d6b 212 ProSitePatterns PS00958 Transaldolase active site. 81 98 - T 11-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 UP12_17320 127891db19d08dda0d19efbd9af98d6b 212 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 1.2E-106 T 11-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UP12_17320 127891db19d08dda0d19efbd9af98d6b 212 Hamap MF_00494 Probable transaldolase [tal]. 1 211 45.799 T 11-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 UP12_17320 127891db19d08dda0d19efbd9af98d6b 212 SUPERFAMILY SSF51569 1 212 2.3E-74 T 11-10-2018 UP12_17320 127891db19d08dda0d19efbd9af98d6b 212 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 11-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 UP12_17320 127891db19d08dda0d19efbd9af98d6b 212 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 202 1.9E-55 T 11-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 UP12_17320 127891db19d08dda0d19efbd9af98d6b 212 Gene3D G3DSA:3.20.20.70 1 212 4.5E-91 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_08545 0f2a12591de10b87cea49c5299773db6 180 Gene3D G3DSA:3.40.630.30 2 173 4.9E-36 T 11-10-2018 UP12_08545 0f2a12591de10b87cea49c5299773db6 180 Pfam PF13302 Acetyltransferase (GNAT) domain 8 140 3.4E-24 T 11-10-2018 IPR000182 GNAT domain UP12_08545 0f2a12591de10b87cea49c5299773db6 180 SUPERFAMILY SSF55729 2 150 5.83E-33 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_04835 434d9b893b2f9e82f559ca133555da75 491 Pfam PF06628 Catalase-related immune-responsive 417 478 1.2E-17 T 11-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 SUPERFAMILY SSF56634 3 485 1.83E-211 T 11-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 336 344 - T 11-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 PRINTS PR00067 Catalase signature 126 144 2.0E-76 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 PRINTS PR00067 Catalase signature 323 349 2.0E-76 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 PRINTS PR00067 Catalase signature 291 318 2.0E-76 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 PRINTS PR00067 Catalase signature 107 124 2.0E-76 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 PRINTS PR00067 Catalase signature 86 104 2.0E-76 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 PRINTS PR00067 Catalase signature 23 46 2.0E-76 T 11-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 PIRSF PIRSF038928 1 483 2.1E-199 T 11-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 Gene3D G3DSA:2.40.180.10 1 491 1.3E-238 T 11-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 Pfam PF00199 Catalase 10 390 7.5E-186 T 11-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 ProSitePatterns PS00438 Catalase proximal active site signature. 46 62 - T 11-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_04835 434d9b893b2f9e82f559ca133555da75 491 SMART SM01060 10 393 3.4E-275 T 11-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 UP12_11165 e1034d7d91b523a9d0e9462cdfd0e6d2 166 Pfam PF15980 Putative Competence protein ComGF 58 152 9.4E-20 T 11-10-2018 IPR016977 Competence operon G, ComGF UP12_01420 13fbdd20f14d15dedcdae572eb434575 372 Pfam PF02378 Phosphotransferase system, EIIC 14 285 1.2E-10 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_01420 13fbdd20f14d15dedcdae572eb434575 372 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 6 337 8.5E-60 T 11-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 UP12_04565 89ac617e809d8f6feaaae7ee43b8beda 181 PIRSF PIRSF000709 2 75 0.004 T 11-10-2018 UP12_04565 89ac617e809d8f6feaaae7ee43b8beda 181 SMART SM00855 3 141 5.8E-6 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UP12_04565 89ac617e809d8f6feaaae7ee43b8beda 181 Gene3D G3DSA:3.40.50.1240 1 172 3.8E-30 T 11-10-2018 IPR029033 Histidine phosphatase superfamily UP12_04565 89ac617e809d8f6feaaae7ee43b8beda 181 SUPERFAMILY SSF53254 1 174 1.36E-30 T 11-10-2018 IPR029033 Histidine phosphatase superfamily UP12_04565 89ac617e809d8f6feaaae7ee43b8beda 181 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 167 6.4E-25 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 UP12_17150 8273204c888b43dc17dcc68cd184ef5e 341 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 5 328 3.7E-134 T 11-10-2018 IPR014225 Sporulation stage II, protein D firmicutes UP12_17150 8273204c888b43dc17dcc68cd184ef5e 341 Pfam PF08486 Stage II sporulation protein 66 169 1.0E-25 T 11-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal UP12_17150 8273204c888b43dc17dcc68cd184ef5e 341 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 69 328 1.9E-72 T 11-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 UP12_06835 922246d4f57d1b02ea0cf9aaba4569e2 63 Pfam PF14156 Antirepressor AbbA 2 62 4.8E-34 T 11-10-2018 IPR025446 Antirepressor AbbA UP12_06835 922246d4f57d1b02ea0cf9aaba4569e2 63 ProDom PD054279 YKZF 25 63 2.0E-12 T 11-10-2018 UP12_03070 6df2ae4edb60b0fbcce4e0c3f294e9f3 291 SUPERFAMILY SSF103481 186 289 3.27E-18 T 11-10-2018 UP12_03070 6df2ae4edb60b0fbcce4e0c3f294e9f3 291 SUPERFAMILY SSF103481 41 140 6.15E-13 T 11-10-2018 UP12_03070 6df2ae4edb60b0fbcce4e0c3f294e9f3 291 Pfam PF00892 EamA-like transporter family 6 139 6.3E-22 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_03070 6df2ae4edb60b0fbcce4e0c3f294e9f3 291 Pfam PF00892 EamA-like transporter family 151 287 2.3E-25 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 34.407 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 410 8.7E-157 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 Gene3D G3DSA:3.40.50.800 325 418 2.3E-27 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 PIRSF PIRSF001549 1 422 3.7E-121 T 11-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 SUPERFAMILY SSF55681 4 317 2.68E-95 T 11-10-2018 UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 Pfam PF03129 Anticodon binding domain 332 420 2.4E-18 T 11-10-2018 IPR004154 Anticodon-binding UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 SUPERFAMILY SSF52954 329 419 3.47E-26 T 11-10-2018 UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 Pfam PF13393 Histidyl-tRNA synthetase 8 312 2.8E-48 T 11-10-2018 UP12_12065 c4bd45cc4ae562a26a4b4a6c99b4d2d9 424 Gene3D G3DSA:3.30.930.10 2 323 8.1E-116 T 11-10-2018 UP12_13430 e5ae78479a50a59093495f97e77361eb 156 Pfam PF12732 YtxH-like protein 12 93 1.6E-17 T 11-10-2018 IPR024623 Uncharacterised protein family YtxH UP12_13430 e5ae78479a50a59093495f97e77361eb 156 Gene3D G3DSA:1.20.120.20 32 156 2.5E-7 T 11-10-2018 UP12_01290 cd95b6b47598663803833d772839df63 117 SMART SM00450 27 117 1.5E-16 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_01290 cd95b6b47598663803833d772839df63 117 Gene3D G3DSA:3.40.250.10 24 117 9.4E-29 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_01290 cd95b6b47598663803833d772839df63 117 Pfam PF00581 Rhodanese-like domain 31 116 5.5E-17 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_01290 cd95b6b47598663803833d772839df63 117 SUPERFAMILY SSF52821 6 116 5.89E-31 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_12655 e9810299391c0212cd0b1019bce35b14 570 Gene3D G3DSA:3.40.50.300 43 254 8.9E-18 T 11-10-2018 UP12_12655 e9810299391c0212cd0b1019bce35b14 570 Pfam PF03354 Phage Terminase 81 552 2.2E-95 T 11-10-2018 IPR005021 Terminase large subunit, Lambdalikevirus-type UP12_04440 e2a4f1c6e1e1ad6d12e2d287aca88873 115 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 1 113 1.0E-54 T 11-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 UP12_04440 e2a4f1c6e1e1ad6d12e2d287aca88873 115 Hamap MF_01502 UPF0295 protein . 1 115 36.234 T 11-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 UP12_04440 e2a4f1c6e1e1ad6d12e2d287aca88873 115 Pfam PF11023 Zinc-ribbon containing domain 3 113 7.9E-59 T 11-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 UP12_11690 622b9144d6863bdd72125716d91b2f75 373 Gene3D G3DSA:1.25.40.10 1 373 2.3E-113 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_11690 622b9144d6863bdd72125716d91b2f75 373 SUPERFAMILY SSF48452 100 304 4.44E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_11690 622b9144d6863bdd72125716d91b2f75 373 Pfam PF13181 Tetratricopeptide repeat 218 244 0.0015 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 Gene3D G3DSA:3.55.50.40 281 369 4.7E-15 T 11-10-2018 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 PRINTS PR01002 Flagellar protein FlgJ signature 126 144 1.2E-8 T 11-10-2018 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 PRINTS PR01002 Flagellar protein FlgJ signature 41 62 1.2E-8 T 11-10-2018 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 PRINTS PR01002 Flagellar protein FlgJ signature 84 105 1.2E-8 T 11-10-2018 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 Pfam PF06605 Prophage endopeptidase tail 220 562 2.1E-69 T 11-10-2018 IPR010572 Prophage tail endopeptidase UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 Gene3D G3DSA:4.10.80.30 57 83 4.5E-43 T 11-10-2018 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 13 144 1.6E-20 T 11-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 Gene3D G3DSA:1.10.530.10 6 149 4.5E-43 T 11-10-2018 UP12_12585 2c9a83eccda4f90133de8f6f421ae3c2 583 SMART SM00047 2 149 7.3E-50 T 11-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 Pfam PF00581 Rhodanese-like domain 8 105 3.6E-10 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 SMART SM00450 7 109 3.6E-14 T 11-10-2018 IPR001763 Rhodanese-like domain UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 Pfam PF00753 Metallo-beta-lactamase superfamily 130 276 7.6E-11 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 SUPERFAMILY SSF56281 124 370 2.17E-40 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 SMART SM00849 130 294 1.5E-25 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 Gene3D G3DSA:3.40.250.10 2 112 2.1E-17 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 SUPERFAMILY SSF52821 2 110 6.42E-18 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily UP12_01300 9fbae30ac6d85234b90adf594d0cf46e 375 Gene3D G3DSA:3.60.15.10 119 355 2.7E-48 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_09630 0e45ce4d8d36cd37505feb99dfdf965d 276 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 124 253 3.8E-46 T 11-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 UP12_09630 0e45ce4d8d36cd37505feb99dfdf965d 276 Gene3D G3DSA:3.30.1380.10 60 276 1.7E-90 T 11-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UP12_09630 0e45ce4d8d36cd37505feb99dfdf965d 276 SUPERFAMILY SSF55166 109 259 2.25E-38 T 11-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 UP12_05220 e4bfbde4ea9533e4f39ac2ff1b5bdd46 431 Pfam PF11563 Protoglobin 30 184 5.6E-41 T 11-10-2018 UP12_05220 e4bfbde4ea9533e4f39ac2ff1b5bdd46 431 SUPERFAMILY SSF46458 28 177 1.69E-37 T 11-10-2018 IPR009050 Globin-like superfamily UP12_05220 e4bfbde4ea9533e4f39ac2ff1b5bdd46 431 SUPERFAMILY SSF58104 199 429 3.01E-48 T 11-10-2018 UP12_05220 e4bfbde4ea9533e4f39ac2ff1b5bdd46 431 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 251 420 5.7E-29 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_05220 e4bfbde4ea9533e4f39ac2ff1b5bdd46 431 Gene3D G3DSA:1.10.287.950 206 430 5.9E-40 T 11-10-2018 UP12_05220 e4bfbde4ea9533e4f39ac2ff1b5bdd46 431 SMART SM00283 193 426 3.2E-21 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 UP12_05220 e4bfbde4ea9533e4f39ac2ff1b5bdd46 431 Gene3D G3DSA:1.10.490.10 24 177 3.1E-40 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 UP12_01610 6e1884957ec69318e6a4481eaa70a511 142 Pfam PF07486 Cell Wall Hydrolase 24 128 7.1E-19 T 11-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 UP12_01610 6e1884957ec69318e6a4481eaa70a511 142 Gene3D G3DSA:1.10.10.2520 8 91 1.3E-12 T 11-10-2018 UP12_16105 f9c12426a6ccbc88176d38259433b72a 272 SMART SM00382 30 225 1.5E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_16105 f9c12426a6ccbc88176d38259433b72a 272 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_16105 f9c12426a6ccbc88176d38259433b72a 272 Gene3D G3DSA:3.40.50.300 2 270 2.3E-67 T 11-10-2018 UP12_16105 f9c12426a6ccbc88176d38259433b72a 272 SUPERFAMILY SSF52540 3 252 7.62E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_16105 f9c12426a6ccbc88176d38259433b72a 272 Pfam PF00005 ABC transporter 22 176 5.2E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_09695 d1bd35217033cdc765c6e57acdf6e8ae 238 SUPERFAMILY SSF53448 6 233 6.82E-30 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_09695 d1bd35217033cdc765c6e57acdf6e8ae 238 Pfam PF02348 Cytidylyltransferase 25 189 1.8E-12 T 11-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 UP12_09695 d1bd35217033cdc765c6e57acdf6e8ae 238 Gene3D G3DSA:3.90.550.10 4 233 2.0E-40 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_15660 d01f22aecc7b34655465b79f452550f5 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 4.9E-6 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_15660 d01f22aecc7b34655465b79f452550f5 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 4.9E-6 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_15660 d01f22aecc7b34655465b79f452550f5 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 4.9E-6 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_15660 d01f22aecc7b34655465b79f452550f5 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 4.9E-6 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_15660 d01f22aecc7b34655465b79f452550f5 142 SMART SM00347 25 125 1.0E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_15660 d01f22aecc7b34655465b79f452550f5 142 Gene3D G3DSA:1.10.10.10 2 140 4.5E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_15660 d01f22aecc7b34655465b79f452550f5 142 SUPERFAMILY SSF46785 10 139 1.64E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_15660 d01f22aecc7b34655465b79f452550f5 142 Pfam PF13463 Winged helix DNA-binding domain 33 98 3.9E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_12780 8b3303ea047c0ef131f771bce39df476 367 SUPERFAMILY SSF47413 6 65 5.91E-8 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.2E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.2E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.2E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.2E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.2E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.2E-38 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 SUPERFAMILY SSF51735 6 253 3.33E-84 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_01615 732d37d5e005095a9de79f8c210fed60 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 2.7E-69 T 11-10-2018 UP12_01615 732d37d5e005095a9de79f8c210fed60 259 Gene3D G3DSA:3.40.50.720 2 257 4.5E-81 T 11-10-2018 UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 2.8E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.8E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.8E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01615 732d37d5e005095a9de79f8c210fed60 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_04930 6db980e58a817e8301b99e1ed3fdc38e 284 Pfam PF01522 Polysaccharide deacetylase 83 193 1.2E-27 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_04930 6db980e58a817e8301b99e1ed3fdc38e 284 SUPERFAMILY SSF88713 83 279 1.14E-48 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_04930 6db980e58a817e8301b99e1ed3fdc38e 284 Gene3D G3DSA:3.20.20.370 45 282 7.1E-56 T 11-10-2018 UP12_16620 d8f4557878af6e18531eb1502ed5b7a4 355 ProSitePatterns PS01348 MraY family signature 2. 150 161 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_16620 d8f4557878af6e18531eb1502ed5b7a4 355 Pfam PF00953 Glycosyl transferase family 4 76 230 4.0E-43 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 2 459 34.318 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 Pfam PF12631 MnmE helical domain 127 456 8.6E-60 T 11-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 Pfam PF01926 50S ribosome-binding GTPase 225 336 2.3E-25 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 Gene3D G3DSA:1.20.120.430 125 459 2.7E-108 T 11-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 Pfam PF10396 GTP-binding protein TrmE N-terminus 3 124 6.9E-41 T 11-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 225 371 1.6E-28 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 Gene3D G3DSA:3.30.1360.120 1 124 1.9E-48 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 Gene3D G3DSA:3.40.50.300 222 387 2.7E-108 T 11-10-2018 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 PRINTS PR00449 Transforming protein P21 ras signature 262 284 6.3E-6 T 11-10-2018 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 PRINTS PR00449 Transforming protein P21 ras signature 222 243 6.3E-6 T 11-10-2018 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 PRINTS PR00449 Transforming protein P21 ras signature 326 339 6.3E-6 T 11-10-2018 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 9 459 5.3E-131 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 UP12_19165 7357acf0b6c10517bfbcc136488fedf9 459 SUPERFAMILY SSF52540 78 375 4.46E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03575 2ff79360e7f6498b5b1ee6cb57f90818 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.2E-24 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UP12_03575 2ff79360e7f6498b5b1ee6cb57f90818 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 3.0E-37 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UP12_03575 2ff79360e7f6498b5b1ee6cb57f90818 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 26.632 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 UP12_03575 2ff79360e7f6498b5b1ee6cb57f90818 96 Gene3D G3DSA:1.10.20.60 1 94 6.0E-35 T 11-10-2018 UP12_03575 2ff79360e7f6498b5b1ee6cb57f90818 96 SUPERFAMILY SSF141000 3 94 4.84E-34 T 11-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 UP12_14520 53ee424f91562573a8595f225b2430f8 70 Pfam PF10960 BhlA holin family 1 64 3.6E-23 T 11-10-2018 IPR024405 Prophage protein BhlA/UviB UP12_14520 53ee424f91562573a8595f225b2430f8 70 ProDom PD019268 UVIB BACTERIOCIN BHLA PLASMID ANTIBIOTIC HOLIN-LIKE PRECURSOR ANTIMICROBIAL SIGNAL PROPHAGE-DERIVED 1 64 6.0E-23 T 11-10-2018 IPR024405 Prophage protein BhlA/UviB UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 SUPERFAMILY SSF50129 14 143 1.49E-30 T 11-10-2018 IPR011032 GroES-like superfamily UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 SUPERFAMILY SSF51735 117 285 4.6E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 90 4.5E-7 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 SMART SM00829 5 332 1.2E-12 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 335 3.8E-137 T 11-10-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 Pfam PF13602 Zinc-binding dehydrogenase 191 332 5.0E-19 T 11-10-2018 UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 Gene3D G3DSA:3.40.50.720 128 273 3.7E-109 T 11-10-2018 UP12_04235 bb579381a8672e1f0d2084fe591c01ce 341 Gene3D G3DSA:3.90.180.10 29 331 3.7E-109 T 11-10-2018 UP12_17215 0aef00396e06cd4044d0db248d230223 127 Pfam PF03899 ATP synthase I chain 10 105 9.7E-17 T 11-10-2018 IPR005598 ATP synthase protein I UP12_17215 0aef00396e06cd4044d0db248d230223 127 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 127 5.0E-40 T 11-10-2018 UP12_19080 9873c3755ffee481467678795ee5f32a 505 Gene3D G3DSA:1.10.3720.10 12 204 4.3E-35 T 11-10-2018 IPR035906 MetI-like superfamily UP12_19080 9873c3755ffee481467678795ee5f32a 505 SUPERFAMILY SSF53850 235 503 1.41E-71 T 11-10-2018 UP12_19080 9873c3755ffee481467678795ee5f32a 505 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 208 5.0E-27 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_19080 9873c3755ffee481467678795ee5f32a 505 Gene3D G3DSA:3.40.190.120 339 442 2.9E-94 T 11-10-2018 UP12_19080 9873c3755ffee481467678795ee5f32a 505 SUPERFAMILY SSF161098 14 198 4.97E-42 T 11-10-2018 IPR035906 MetI-like superfamily UP12_19080 9873c3755ffee481467678795ee5f32a 505 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 235 500 9.3E-63 T 11-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 UP12_19080 9873c3755ffee481467678795ee5f32a 505 Gene3D G3DSA:3.40.190.10 246 503 2.9E-94 T 11-10-2018 UP12_12520 6e87dfaab4393436935c84331b06d30a 242 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 1.0E-9 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_12520 6e87dfaab4393436935c84331b06d30a 242 SUPERFAMILY SSF54211 1 182 1.62E-43 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_12520 6e87dfaab4393436935c84331b06d30a 242 Pfam PF01138 3' exoribonuclease family, domain 1 10 138 1.9E-23 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_12520 6e87dfaab4393436935c84331b06d30a 242 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 3.4E-116 T 11-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 UP12_12520 6e87dfaab4393436935c84331b06d30a 242 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 11-10-2018 IPR018336 Ribonuclease PH, conserved site UP12_12520 6e87dfaab4393436935c84331b06d30a 242 SUPERFAMILY SSF55666 153 235 1.7E-23 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_12520 6e87dfaab4393436935c84331b06d30a 242 Gene3D G3DSA:3.30.230.70 9 238 6.1E-62 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 UP12_12520 6e87dfaab4393436935c84331b06d30a 242 Hamap MF_00564 Ribonuclease PH [rph]. 11 238 44.34 T 11-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 105 4.7E-28 T 11-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 Pfam PF13242 HAD-hyrolase-like 178 250 7.3E-23 T 11-10-2018 UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 PIRSF PIRSF000915 1 256 3.5E-59 T 11-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 3 251 5.7E-133 T 11-10-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 Gene3D G3DSA:3.40.50.1000 4 229 1.3E-87 T 11-10-2018 IPR023214 HAD superfamily UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 SUPERFAMILY SSF56784 2 252 5.73E-74 T 11-10-2018 IPR036412 HAD-like superfamily UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 227 1.4E-40 T 11-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA UP12_15210 8b4ccff20a0a8a3b288532e77e9b786e 256 Gene3D G3DSA:3.40.50.1000 83 178 1.3E-87 T 11-10-2018 IPR023214 HAD superfamily UP12_04910 4d6a8b7e547d7f0aaf1092e533906b5e 131 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 5 113 1.2E-24 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UP12_04910 4d6a8b7e547d7f0aaf1092e533906b5e 131 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 118 17.715 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UP12_04910 4d6a8b7e547d7f0aaf1092e533906b5e 131 TIGRFAM TIGR00494 crcB: protein CrcB 5 117 5.3E-26 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 Gene3D G3DSA:4.10.910.10 72 121 6.2E-26 T 11-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 11-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.97 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 8.8E-35 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 Gene3D G3DSA:1.10.8.50 1 71 2.3E-29 T 11-10-2018 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 SUPERFAMILY SSF46946 2 114 4.84E-46 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 4.3E-53 T 11-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_00855 0aefb7c9d7ae4aba718949d49054857e 121 PIRSF PIRSF002134 1 121 1.1E-42 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_11825 f844b15f80729ae45ab967cde14c3986 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 116 4.1E-20 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_11825 f844b15f80729ae45ab967cde14c3986 232 SUPERFAMILY SSF161098 16 215 3.53E-34 T 11-10-2018 IPR035906 MetI-like superfamily UP12_11825 f844b15f80729ae45ab967cde14c3986 232 Gene3D G3DSA:1.10.3720.10 9 226 5.2E-44 T 11-10-2018 IPR035906 MetI-like superfamily UP12_11825 f844b15f80729ae45ab967cde14c3986 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 223 8.6E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 Gene3D G3DSA:3.60.20.10 2 239 1.2E-70 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 38.986 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 Pfam PF01380 SIS domain 288 413 8.8E-35 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 Pfam PF01380 SIS domain 461 582 1.0E-18 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 7.7E-232 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 Gene3D G3DSA:3.40.50.10490 444 600 2.9E-62 T 11-10-2018 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 Gene3D G3DSA:3.40.50.10490 243 442 2.3E-62 T 11-10-2018 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 SUPERFAMILY SSF53697 244 600 5.08E-97 T 11-10-2018 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 Pfam PF13522 Glutamine amidotransferase domain 62 192 4.2E-21 T 11-10-2018 UP12_01080 7bfd8533183e3c788f8d8286d0483dc7 600 SUPERFAMILY SSF56235 2 234 4.2E-65 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal UP12_13490 825a02a626e472638e44ff3411369ade 282 SMART SM00849 50 257 1.7E-16 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_13490 825a02a626e472638e44ff3411369ade 282 Pfam PF00753 Metallo-beta-lactamase superfamily 55 244 1.6E-13 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_13490 825a02a626e472638e44ff3411369ade 282 SUPERFAMILY SSF56281 3 263 9.83E-44 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_13490 825a02a626e472638e44ff3411369ade 282 Gene3D G3DSA:3.60.15.10 4 269 2.0E-86 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_18265 972833e1d6eeda2dad3054fce758e638 473 Gene3D G3DSA:3.40.980.20 288 473 4.3E-13 T 11-10-2018 UP12_18265 972833e1d6eeda2dad3054fce758e638 473 SUPERFAMILY SSF142764 35 471 1.57E-66 T 11-10-2018 UP12_18265 972833e1d6eeda2dad3054fce758e638 473 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 300 464 5.9E-38 T 11-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain UP12_18265 972833e1d6eeda2dad3054fce758e638 473 Gene3D G3DSA:3.40.50.10840 42 278 5.4E-13 T 11-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily UP12_18265 972833e1d6eeda2dad3054fce758e638 473 Pfam PF07005 Putative sugar-binding N-terminal domain 34 276 1.4E-56 T 11-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain UP12_06585 b2fb6199a1cd4b7845be08cde5c52354 176 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 176 30.249 T 11-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 UP12_06585 b2fb6199a1cd4b7845be08cde5c52354 176 Pfam PF03079 ARD/ARD' family 4 169 1.2E-44 T 11-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 UP12_06585 b2fb6199a1cd4b7845be08cde5c52354 176 Gene3D G3DSA:2.60.120.10 1 171 2.3E-58 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_06585 b2fb6199a1cd4b7845be08cde5c52354 176 SUPERFAMILY SSF51182 10 174 4.05E-32 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_13605 086ec38ca5d642428677fe71d70256bd 370 SUPERFAMILY SSF48208 12 364 5.39E-80 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 UP12_13605 086ec38ca5d642428677fe71d70256bd 370 Pfam PF07470 Glycosyl Hydrolase Family 88 14 364 2.6E-117 T 11-10-2018 IPR010905 Glycosyl hydrolase, family 88 UP12_13605 086ec38ca5d642428677fe71d70256bd 370 Gene3D G3DSA:1.50.10.10 1 366 4.0E-145 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 UP12_04715 050f08174a137ca948808c26c383da23 168 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 26 164 1.8E-27 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like UP12_04715 050f08174a137ca948808c26c383da23 168 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 8 165 7.4E-49 T 11-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 282 3.7E-23 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 Gene3D G3DSA:3.50.50.60 115 226 6.6E-86 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.5E-13 T 11-10-2018 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 269 2.5E-13 T 11-10-2018 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.5E-13 T 11-10-2018 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 Gene3D G3DSA:3.50.50.60 4 287 6.6E-86 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 124 136 3.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 139 163 3.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 3.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 257 275 3.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 3.6E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 UP12_03665 0719213c7136d54cdafeb7cd005e8196 304 SUPERFAMILY SSF51905 4 294 2.67E-31 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_02860 3b9501827846acfc13507f4a17ff5062 349 SUPERFAMILY SSF51735 151 314 3.12E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_02860 3b9501827846acfc13507f4a17ff5062 349 SUPERFAMILY SSF50129 13 174 3.04E-52 T 11-10-2018 IPR011032 GroES-like superfamily UP12_02860 3b9501827846acfc13507f4a17ff5062 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 UP12_02860 3b9501827846acfc13507f4a17ff5062 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 146 6.7E-27 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_02860 3b9501827846acfc13507f4a17ff5062 349 Gene3D G3DSA:3.40.50.720 162 316 1.3E-137 T 11-10-2018 UP12_02860 3b9501827846acfc13507f4a17ff5062 349 Gene3D G3DSA:3.90.180.10 16 344 1.3E-137 T 11-10-2018 UP12_02860 3b9501827846acfc13507f4a17ff5062 349 SMART SM00829 8 344 6.8E-7 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_02860 3b9501827846acfc13507f4a17ff5062 349 Pfam PF00107 Zinc-binding dehydrogenase 188 310 4.2E-24 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 UP12_04550 25ae0c43f654ebaf8271092ff8082775 264 Gene3D G3DSA:3.90.1200.10 85 245 5.5E-10 T 11-10-2018 UP12_04550 25ae0c43f654ebaf8271092ff8082775 264 Pfam PF01636 Phosphotransferase enzyme family 121 176 7.2E-11 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase UP12_04550 25ae0c43f654ebaf8271092ff8082775 264 SUPERFAMILY SSF56112 9 263 7.07E-24 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_14645 668cd21dcfcfc5d909472a5a3a1edf3a 214 Pfam PF13384 Homeodomain-like domain 12 46 3.0E-7 T 11-10-2018 UP12_05525 8bb664db9e651f11af91a83c51bc9eb8 151 Gene3D G3DSA:2.60.40.2360 33 151 3.4E-40 T 11-10-2018 IPR038144 Intracellular proteinase inhibitor UP12_05525 8bb664db9e651f11af91a83c51bc9eb8 151 Pfam PF12690 Intracellular proteinase inhibitor 51 127 1.0E-26 T 11-10-2018 IPR020481 Intracellular proteinase inhibitor BsuPI UP12_05525 8bb664db9e651f11af91a83c51bc9eb8 151 ProDom PD076312 INHIBITOR INTRACELLULAR PROTEINASE PRECURSOR SIGNAL DOMAIN SLH S-LAYER PROTEASE BSUPI 33 151 8.0E-34 T 11-10-2018 IPR020481 Intracellular proteinase inhibitor BsuPI UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 SUPERFAMILY SSF52540 5 231 8.75E-5 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 1 1162 65.11 T 11-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 Gene3D G3DSA:3.40.50.300 562 700 1.0E-44 T 11-10-2018 UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 Gene3D G3DSA:3.40.50.300 280 448 1.6E-30 T 11-10-2018 UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 Gene3D G3DSA:3.40.50.300 118 277 1.0E-33 T 11-10-2018 UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 Pfam PF12705 PD-(D/E)XK nuclease superfamily 791 1131 7.2E-60 T 11-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 2 1161 0.0 T 11-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 UP12_05315 e61a9ab4c3055a7f26c51f82f18d3cd9 1169 SUPERFAMILY SSF52540 294 749 4.43E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13525 ef1efb2e6095877eae06e3a482cfda4a 309 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 UP12_13525 ef1efb2e6095877eae06e3a482cfda4a 309 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 307 7.0E-123 T 11-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 UP12_13525 ef1efb2e6095877eae06e3a482cfda4a 309 SUPERFAMILY SSF53686 1 307 1.44E-94 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UP12_13525 ef1efb2e6095877eae06e3a482cfda4a 309 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 307 4.2E-129 T 11-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 UP12_13525 ef1efb2e6095877eae06e3a482cfda4a 309 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 293 3.8E-68 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UP12_13525 ef1efb2e6095877eae06e3a482cfda4a 309 Gene3D G3DSA:3.40.50.1100 45 144 2.9E-113 T 11-10-2018 UP12_13525 ef1efb2e6095877eae06e3a482cfda4a 309 Gene3D G3DSA:3.40.50.1100 6 303 2.9E-113 T 11-10-2018 UP12_06190 23769bf639f24cd343a0b6144e781850 155 SUPERFAMILY SSF55804 7 151 8.37E-41 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_06190 23769bf639f24cd343a0b6144e781850 155 Gene3D G3DSA:3.40.930.10 2 155 2.7E-50 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_06190 23769bf639f24cd343a0b6144e781850 155 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 151 1.1E-35 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_05630 3e68bb6e884e2e5d794520cd2f11bca1 65 ProDom PD027277 REPRESSOR COMZ COMG OPERON TRANSCRIPTION POSSIBLE COMPETENCE PROTEIN-RELATED BH2888 REGULATION 3 57 2.0E-16 T 11-10-2018 IPR024558 ComZ UP12_05630 3e68bb6e884e2e5d794520cd2f11bca1 65 Pfam PF10815 ComZ 4 58 5.0E-32 T 11-10-2018 IPR024558 ComZ UP12_11835 1e8afcdad376d1a1cdab9d4f8df4be45 276 SUPERFAMILY SSF47240 1 274 2.98E-104 T 11-10-2018 IPR009078 Ferritin-like superfamily UP12_11835 1e8afcdad376d1a1cdab9d4f8df4be45 276 Gene3D G3DSA:1.20.1260.130 2 276 8.8E-90 T 11-10-2018 UP12_11835 1e8afcdad376d1a1cdab9d4f8df4be45 276 Pfam PF05067 Manganese containing catalase 1 271 2.8E-127 T 11-10-2018 IPR007760 Manganese catalase UP12_15200 be7ff21732e591af0e001a742d620e10 336 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 2 312 1.4E-112 T 11-10-2018 IPR014254 Spore coat protein YutH UP12_15200 be7ff21732e591af0e001a742d620e10 336 Gene3D G3DSA:3.90.1200.10 96 311 7.7E-25 T 11-10-2018 UP12_15200 be7ff21732e591af0e001a742d620e10 336 SUPERFAMILY SSF56112 38 314 3.16E-14 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_05465 7a37dcec881673a3f9c2b4a68ca0d699 184 SMART SM01006 8 55 9.8E-11 T 11-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain UP12_05465 7a37dcec881673a3f9c2b4a68ca0d699 184 Gene3D G3DSA:3.40.630.30 1 182 5.1E-55 T 11-10-2018 UP12_05465 7a37dcec881673a3f9c2b4a68ca0d699 184 Pfam PF13523 Acetyltransferase (GNAT) domain 12 155 1.0E-49 T 11-10-2018 UP12_05465 7a37dcec881673a3f9c2b4a68ca0d699 184 SUPERFAMILY SSF55729 4 170 2.42E-49 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 SUPERFAMILY SSF51445 2 464 1.94E-135 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 375 8.4E-11 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 8.4E-11 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 8.4E-11 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 295 309 8.4E-11 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 8.4E-11 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 Gene3D G3DSA:3.20.20.80 3 467 1.1E-122 T 11-10-2018 UP12_18155 24b52eb1bcc41202fbc03b5e09287478 477 Pfam PF00232 Glycosyl hydrolase family 1 5 466 9.3E-102 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 SUPERFAMILY SSF53223 3 101 1.15E-32 T 11-10-2018 UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 117 220 8.2E-11 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 3.9E-30 T 11-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 275 3.9E-99 T 11-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 Gene3D G3DSA:3.40.50.720 101 241 1.4E-93 T 11-10-2018 UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 SUPERFAMILY SSF51735 102 274 1.97E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 273 34.868 T 11-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 UP12_11660 f8b94f70417484bc8db14529988ee9e1 280 Gene3D G3DSA:3.40.50.10860 5 262 1.4E-93 T 11-10-2018 UP12_02455 17d38c4d7bf84222b241b57ce14e85c3 340 Pfam PF01594 AI-2E family transporter 16 334 1.4E-52 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like UP12_03750 f490894914d22f1d7acb93869e8f2650 471 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 24 464 7.3E-88 T 11-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UP12_03750 f490894914d22f1d7acb93869e8f2650 471 Pfam PF00939 Sodium:sulfate symporter transmembrane region 11 465 2.1E-79 T 11-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 UP12_14605 8ae19a9f8432a27ada9a63b53845ab5b 151 ProDom PD033466 XKDJ PHAGE PHAGE-LIKE PBSX RELATED LIN1276 ELEMENT YQBJ 1 145 1.0E-38 T 11-10-2018 UP12_10545 13f314e1436993b83edb04ba6afa38f6 206 Pfam PF12164 Stage V sporulation protein AA 4 88 3.4E-20 T 11-10-2018 IPR021997 Stage V sporulation protein AA UP12_10545 13f314e1436993b83edb04ba6afa38f6 206 Gene3D G3DSA:2.60.480.10 1 97 6.8E-13 T 11-10-2018 IPR038548 Stage V sporulation protein AA, N-terminal domain superfamily UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 Pfam PF00664 ABC transporter transmembrane region 17 286 2.3E-59 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 Gene3D G3DSA:3.40.50.300 329 570 2.1E-92 T 11-10-2018 UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 Gene3D G3DSA:1.20.1560.10 1 315 9.6E-81 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 SUPERFAMILY SSF52540 325 569 5.43E-91 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 SMART SM00382 358 544 5.7E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 SUPERFAMILY SSF90123 3 316 2.22E-79 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 Pfam PF00005 ABC transporter 349 498 6.6E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_17425 8f9d1602ab13851842dec1683ec61be3 571 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_01250 6137f75e4fc26d9b0862d9eda552c52e 191 Gene3D G3DSA:1.10.10.60 1 65 8.0E-25 T 11-10-2018 UP12_01250 6137f75e4fc26d9b0862d9eda552c52e 191 Pfam PF16925 Bacterial transcriptional repressor C-terminal 98 188 1.6E-6 T 11-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal UP12_01250 6137f75e4fc26d9b0862d9eda552c52e 191 SUPERFAMILY SSF46689 1 72 2.26E-15 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_01250 6137f75e4fc26d9b0862d9eda552c52e 191 Gene3D G3DSA:1.10.357.10 69 191 4.2E-25 T 11-10-2018 UP12_01250 6137f75e4fc26d9b0862d9eda552c52e 191 SUPERFAMILY SSF48498 80 190 5.29E-19 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_01250 6137f75e4fc26d9b0862d9eda552c52e 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 1.6E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 Pfam PF00186 Dihydrofolate reductase 1 159 1.5E-66 T 11-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 PRINTS PR00070 Dihydrofolate reductase signature 27 35 2.0E-16 T 11-10-2018 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 PRINTS PR00070 Dihydrofolate reductase signature 91 105 2.0E-16 T 11-10-2018 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 PRINTS PR00070 Dihydrofolate reductase signature 13 23 2.0E-16 T 11-10-2018 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 PRINTS PR00070 Dihydrofolate reductase signature 40 51 2.0E-16 T 11-10-2018 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 SUPERFAMILY SSF53597 1 160 4.63E-61 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 11-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 PIRSF PIRSF000194 1 161 8.3E-66 T 11-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 UP12_09780 9eb6edcbb90b7cbac5b3e16d2ca96895 161 Gene3D G3DSA:3.40.430.10 1 161 2.6E-64 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 UP12_05560 c6b37a47802a7ba2cb2d72b78c4ea814 182 SUPERFAMILY SSF103473 6 178 1.7E-19 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_05560 c6b37a47802a7ba2cb2d72b78c4ea814 182 Pfam PF07690 Major Facilitator Superfamily 13 177 3.8E-12 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_05560 c6b37a47802a7ba2cb2d72b78c4ea814 182 Gene3D G3DSA:1.20.1250.20 4 182 1.5E-18 T 11-10-2018 UP12_04620 efef8d19daf65545e8528e4e01af3fac 301 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 34 90 4.4E-6 T 11-10-2018 IPR008792 Coenzyme PQQ synthesis D UP12_04620 efef8d19daf65545e8528e4e01af3fac 301 Gene3D G3DSA:1.10.10.1150 6 93 2.7E-8 T 11-10-2018 UP12_12395 229a4be72419bca37dfb65072a7d71ae 335 SUPERFAMILY SSF116965 89 292 9.55E-8 T 11-10-2018 UP12_12395 229a4be72419bca37dfb65072a7d71ae 335 Gene3D G3DSA:1.25.40.10 17 132 2.0E-11 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_12395 229a4be72419bca37dfb65072a7d71ae 335 Pfam PF14559 Tetratricopeptide repeat 27 81 8.6E-9 T 11-10-2018 UP12_12395 229a4be72419bca37dfb65072a7d71ae 335 SUPERFAMILY SSF48452 14 122 1.21E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_02845 904d5be3533ad9f836e87308bf6f75b8 316 Pfam PF00082 Subtilase family 34 259 9.3E-34 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 UP12_02845 904d5be3533ad9f836e87308bf6f75b8 316 Gene3D G3DSA:3.40.50.200 19 276 1.5E-63 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_02845 904d5be3533ad9f836e87308bf6f75b8 316 PRINTS PR00723 Subtilisin serine protease family (S8) signature 68 81 1.8E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_02845 904d5be3533ad9f836e87308bf6f75b8 316 PRINTS PR00723 Subtilisin serine protease family (S8) signature 34 53 1.8E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_02845 904d5be3533ad9f836e87308bf6f75b8 316 PRINTS PR00723 Subtilisin serine protease family (S8) signature 220 236 1.8E-11 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related UP12_02845 904d5be3533ad9f836e87308bf6f75b8 316 SUPERFAMILY SSF52743 27 277 4.84E-61 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 UP12_10680 e9777160196b648bfc371dd7f7300df4 149 Pfam PF10787 Uncharacterised protein from bacillus cereus group 2 145 2.2E-67 T 11-10-2018 IPR019723 Uncharacterised protein, YfmQ UP12_08790 755cb29fc978ca8cc1c380bd595e4228 137 Pfam PF13380 CoA binding domain 17 131 5.5E-36 T 11-10-2018 IPR003781 CoA-binding GO:0048037 UP12_08790 755cb29fc978ca8cc1c380bd595e4228 137 SMART SM00881 13 105 9.4E-21 T 11-10-2018 IPR003781 CoA-binding GO:0048037 UP12_08790 755cb29fc978ca8cc1c380bd595e4228 137 SUPERFAMILY SSF51735 7 134 4.93E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08790 755cb29fc978ca8cc1c380bd595e4228 137 Gene3D G3DSA:3.40.50.720 1 137 1.4E-39 T 11-10-2018 UP12_18410 b1de7c343f5b99aa8669f3fe9ffcc7cf 423 Gene3D G3DSA:1.20.1250.20 18 417 4.1E-38 T 11-10-2018 UP12_18410 b1de7c343f5b99aa8669f3fe9ffcc7cf 423 Pfam PF07690 Major Facilitator Superfamily 48 346 5.6E-21 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_18410 b1de7c343f5b99aa8669f3fe9ffcc7cf 423 SUPERFAMILY SSF103473 16 419 4.05E-45 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_16090 101ad190bc7d8520033d43f96a0fd684 469 SUPERFAMILY SSF88713 269 455 2.67E-57 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_16090 101ad190bc7d8520033d43f96a0fd684 469 Pfam PF01522 Polysaccharide deacetylase 273 385 2.8E-29 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_16090 101ad190bc7d8520033d43f96a0fd684 469 Pfam PF13739 Domain of unknown function (DUF4163) 56 134 3.0E-6 T 11-10-2018 IPR025303 Deacetylase PdaC UP12_16090 101ad190bc7d8520033d43f96a0fd684 469 Gene3D G3DSA:3.30.565.40 39 149 2.9E-9 T 11-10-2018 UP12_16090 101ad190bc7d8520033d43f96a0fd684 469 Gene3D G3DSA:3.90.640.20 153 238 2.8E-14 T 11-10-2018 IPR037126 PdaC/RsiV-like superfamily UP12_16090 101ad190bc7d8520033d43f96a0fd684 469 Gene3D G3DSA:3.20.20.370 239 464 1.3E-63 T 11-10-2018 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 PRINTS PR00773 GrpE protein signature 137 152 1.8E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 PRINTS PR00773 GrpE protein signature 164 183 1.8E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 PRINTS PR00773 GrpE protein signature 83 98 1.8E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 PRINTS PR00773 GrpE protein signature 55 71 1.8E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 Hamap MF_01151 Protein GrpE [grpE]. 3 185 21.634 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 ProSitePatterns PS01071 grpE protein signature. 140 183 - T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 SUPERFAMILY SSF58014 34 129 2.75E-27 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 Gene3D G3DSA:3.90.20.20 2 128 2.0E-26 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 Gene3D G3DSA:2.30.22.10 129 185 1.1E-25 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 SUPERFAMILY SSF51064 130 185 1.7E-19 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 UP12_11565 2c3f58d560364f69b5888b58a4d10d4a 185 Pfam PF01025 GrpE 23 185 1.9E-53 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 UP12_11405 7925da390ef5a97a35760c4ea87720d4 232 Pfam PF14181 YqfQ-like protein 47 232 2.3E-36 T 11-10-2018 IPR025571 YqfQ-like protein UP12_13330 7ac36b9a8670e34bc52e3953bae62261 447 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 424 2.3E-151 T 11-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 UP12_13330 7ac36b9a8670e34bc52e3953bae62261 447 Pfam PF05525 Branched-chain amino acid transport protein 8 437 1.1E-160 T 11-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 Pfam PF05746 DALR anticodon binding domain 576 671 2.9E-6 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 SUPERFAMILY SSF109604 338 491 2.98E-22 T 11-10-2018 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 678 5.2E-268 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 6.6E-38 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 315 331 6.6E-38 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 6.6E-38 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 6.6E-38 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 243 258 6.6E-38 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 543 4.1E-213 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_11455 13e7d85357bb54d719cd70bfffa7ea64 681 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 678 27.054 T 11-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 UP12_06425 807228f611724a5fc16eed3a40cb7725 228 Gene3D G3DSA:3.40.50.2300 1 124 1.3E-39 T 11-10-2018 UP12_06425 807228f611724a5fc16eed3a40cb7725 228 SMART SM00448 4 115 1.2E-42 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_06425 807228f611724a5fc16eed3a40cb7725 228 Gene3D G3DSA:1.10.10.10 125 228 1.3E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06425 807228f611724a5fc16eed3a40cb7725 228 SUPERFAMILY SSF52172 1 179 2.78E-41 T 11-10-2018 IPR011006 CheY-like superfamily UP12_06425 807228f611724a5fc16eed3a40cb7725 228 SMART SM00862 151 226 1.4E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_06425 807228f611724a5fc16eed3a40cb7725 228 Pfam PF00072 Response regulator receiver domain 6 116 5.8E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 UP12_06425 807228f611724a5fc16eed3a40cb7725 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 226 1.0E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 UP12_06605 a34b11eaf33d0ff5e91599b26721cfef 255 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 58 2.9E-21 T 11-10-2018 IPR025713 Motility protein B, N-terminal domain UP12_06605 a34b11eaf33d0ff5e91599b26721cfef 255 Pfam PF00691 OmpA family 141 241 1.5E-14 T 11-10-2018 IPR006665 OmpA-like domain UP12_06605 a34b11eaf33d0ff5e91599b26721cfef 255 SUPERFAMILY SSF103088 128 250 2.49E-29 T 11-10-2018 IPR036737 OmpA-like domain superfamily UP12_06605 a34b11eaf33d0ff5e91599b26721cfef 255 Gene3D G3DSA:3.30.1330.60 65 254 2.8E-41 T 11-10-2018 IPR036737 OmpA-like domain superfamily UP12_09010 bb20cbfbcb7756932d17aa219ad257d1 418 Gene3D G3DSA:3.40.190.10 141 397 2.0E-120 T 11-10-2018 UP12_09010 bb20cbfbcb7756932d17aa219ad257d1 418 SUPERFAMILY SSF53850 19 417 2.72E-69 T 11-10-2018 UP12_09010 bb20cbfbcb7756932d17aa219ad257d1 418 Pfam PF01547 Bacterial extracellular solute-binding protein 46 336 1.0E-30 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein UP12_09010 bb20cbfbcb7756932d17aa219ad257d1 418 Gene3D G3DSA:3.40.190.10 48 356 2.0E-120 T 11-10-2018 UP12_13005 0e3d5bbcb78b3e11aa2f0a45e341b19c 289 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 3 263 2.4E-66 T 11-10-2018 IPR014199 Sporulation protein YtxC UP12_13005 0e3d5bbcb78b3e11aa2f0a45e341b19c 289 Pfam PF08812 YtxC-like family 52 262 3.9E-54 T 11-10-2018 IPR014199 Sporulation protein YtxC UP12_13005 0e3d5bbcb78b3e11aa2f0a45e341b19c 289 PIRSF PIRSF012563 1 280 4.8E-88 T 11-10-2018 IPR014199 Sporulation protein YtxC UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 Gene3D G3DSA:2.120.10.80 19 153 2.5E-29 T 11-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 Gene3D G3DSA:2.120.10.80 154 334 2.1E-29 T 11-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 Pfam PF01344 Kelch motif 42 87 1.1E-11 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 Pfam PF01344 Kelch motif 90 133 3.4E-7 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 Pfam PF01344 Kelch motif 192 236 4.8E-8 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 SMART SM00612 101 148 2.1 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 SMART SM00612 255 306 0.2 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 SMART SM00612 158 203 11.0 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 SMART SM00612 204 254 2.9 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 SMART SM00612 53 100 2.1E-5 T 11-10-2018 IPR006652 Kelch repeat type 1 GO:0005515 UP12_06105 2629ed7385c26cbf6f9283911668eff8 507 SUPERFAMILY SSF50965 32 322 4.05E-43 T 11-10-2018 IPR011043 Galactose oxidase/kelch, beta-propeller UP12_10000 1d8fe9e18203286a084ff9b3550c509e 318 Pfam PF10720 Protein of unknown function (DUF2515) 11 309 4.7E-127 T 11-10-2018 IPR019658 Protein of unknown function DUF2515 UP12_10405 ff0a4bf03175b4522d75f80c3e6f40a8 392 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 49 392 1.4E-75 T 11-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 UP12_10405 ff0a4bf03175b4522d75f80c3e6f40a8 392 Pfam PF01578 Cytochrome C assembly protein 73 190 1.0E-9 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 UP12_10405 ff0a4bf03175b4522d75f80c3e6f40a8 392 Pfam PF01578 Cytochrome C assembly protein 266 389 8.6E-25 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 UP12_01635 6f1883e1badcf7d447741e658f2a1579 193 Pfam PF02342 TerD domain 2 188 5.9E-83 T 11-10-2018 IPR003325 TerD domain UP12_01635 6f1883e1badcf7d447741e658f2a1579 193 Gene3D G3DSA:2.60.60.30 19 187 5.8E-71 T 11-10-2018 UP12_08575 b8f59d88151f1492f586702afdf05502 231 Pfam PF06912 Protein of unknown function (DUF1275) 14 220 8.9E-38 T 11-10-2018 IPR010699 Protein of unknown function DUF1275 UP12_04355 7f93390cab184f76b66ca693ef7f07fb 326 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 176 6.5E-25 T 11-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase UP12_16660 924a7bf809af262e565052b7134a7dc6 483 Pfam PF13440 Polysaccharide biosynthesis protein 37 326 3.0E-74 T 11-10-2018 UP12_06760 4b822d0a7d7dffd4aef2bbf652c30341 294 Pfam PF01545 Cation efflux family 12 204 2.9E-52 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UP12_06760 4b822d0a7d7dffd4aef2bbf652c30341 294 Gene3D G3DSA:3.30.70.1350 205 293 3.2E-29 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 UP12_06760 4b822d0a7d7dffd4aef2bbf652c30341 294 Gene3D G3DSA:1.20.1510.10 7 204 4.5E-64 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UP12_06760 4b822d0a7d7dffd4aef2bbf652c30341 294 SUPERFAMILY SSF161111 7 206 1.7E-59 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily UP12_06760 4b822d0a7d7dffd4aef2bbf652c30341 294 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 288 2.2E-73 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 UP12_06760 4b822d0a7d7dffd4aef2bbf652c30341 294 Pfam PF16916 Dimerisation domain of Zinc Transporter 211 287 1.0E-22 T 11-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain UP12_06760 4b822d0a7d7dffd4aef2bbf652c30341 294 SUPERFAMILY SSF160240 209 288 1.44E-20 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 11-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 33.017 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 Gene3D G3DSA:2.30.30.790 3 115 1.7E-15 T 11-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 113 1.7E-52 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 PIRSF PIRSF002191 1 115 2.9E-52 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 SUPERFAMILY SSF50104 2 114 1.7E-49 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily UP12_07810 5ebac637417504953ce4fae899d8ffb8 115 Pfam PF01245 Ribosomal protein L19 4 112 3.8E-54 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_09640 f9390b609bf58e76dbc27770c94777b4 105 ProDom PD030115 YODL GK1575 3 105 6.0E-24 T 11-10-2018 UP12_09640 f9390b609bf58e76dbc27770c94777b4 105 Pfam PF14191 YodL-like 32 88 1.1E-5 T 11-10-2018 IPR025923 YodL-like UP12_09190 afd6ef35104adbae35138f6193722cd5 469 Gene3D G3DSA:1.10.45.10 418 458 4.7E-11 T 11-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 UP12_09190 afd6ef35104adbae35138f6193722cd5 469 SUPERFAMILY SSF56176 5 217 6.07E-75 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 UP12_09190 afd6ef35104adbae35138f6193722cd5 469 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 9.1E-177 T 11-10-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 UP12_09190 afd6ef35104adbae35138f6193722cd5 469 Gene3D G3DSA:3.30.465.40 3 237 1.3E-80 T 11-10-2018 UP12_09190 afd6ef35104adbae35138f6193722cd5 469 Pfam PF01565 FAD binding domain 41 179 4.8E-43 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 UP12_09190 afd6ef35104adbae35138f6193722cd5 469 Gene3D G3DSA:3.30.70.2740 336 417 1.8E-14 T 11-10-2018 UP12_09190 afd6ef35104adbae35138f6193722cd5 469 SUPERFAMILY SSF55103 220 458 4.41E-67 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 UP12_09190 afd6ef35104adbae35138f6193722cd5 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 457 1.2E-73 T 11-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 UP12_14090 b7f28a7cc8615224e760ed9447ad1b95 176 Gene3D G3DSA:2.40.50.140 94 176 1.8E-30 T 11-10-2018 UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 4.8E-77 T 11-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 41.931 T 11-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 Gene3D G3DSA:3.40.1390.20 1 131 3.9E-42 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 SUPERFAMILY SSF53795 132 297 1.22E-41 T 11-10-2018 UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 SUPERFAMILY SSF75138 3 131 1.16E-38 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 Gene3D G3DSA:3.40.50.300 132 310 1.2E-75 T 11-10-2018 UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 Pfam PF02603 HPr Serine kinase N terminus 4 127 2.7E-39 T 11-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 UP12_16325 2d1c9bc80775e5710e45f8e4f4dfeccc 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 301 2.7E-118 T 11-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 UP12_10620 6cd592cde6cef5e0a402974acdbaa0bd 185 SUPERFAMILY SSF55811 7 178 2.84E-49 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UP12_10620 6cd592cde6cef5e0a402974acdbaa0bd 185 Gene3D G3DSA:3.90.79.10 3 184 5.3E-55 T 11-10-2018 UP12_10620 6cd592cde6cef5e0a402974acdbaa0bd 185 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 UP12_10620 6cd592cde6cef5e0a402974acdbaa0bd 185 Pfam PF00293 NUDIX domain 42 157 2.3E-19 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UP12_17435 62d5a2eebc3a278965a00f95c465fa90 323 Gene3D G3DSA:3.50.30.60 161 321 5.8E-49 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_17435 62d5a2eebc3a278965a00f95c465fa90 323 SUPERFAMILY SSF52317 1 160 3.2E-43 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like UP12_17435 62d5a2eebc3a278965a00f95c465fa90 323 Gene3D G3DSA:3.40.50.10740 1 159 2.5E-54 T 11-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal UP12_17435 62d5a2eebc3a278965a00f95c465fa90 323 SUPERFAMILY SSF141986 168 315 1.83E-33 T 11-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily UP12_17435 62d5a2eebc3a278965a00f95c465fa90 323 PIRSF PIRSF028757 1 323 3.9E-76 T 11-10-2018 IPR003507 Peptidase family S66 UP12_17435 62d5a2eebc3a278965a00f95c465fa90 323 Pfam PF02016 LD-carboxypeptidase 14 310 1.8E-69 T 11-10-2018 IPR003507 Peptidase family S66 UP12_01845 dc61a21566a18dac879b2b9129ee05ee 257 SUPERFAMILY SSF46785 13 83 9.82E-16 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_01845 dc61a21566a18dac879b2b9129ee05ee 257 SUPERFAMILY SSF55781 77 251 1.37E-41 T 11-10-2018 UP12_01845 dc61a21566a18dac879b2b9129ee05ee 257 Gene3D G3DSA:1.10.10.10 10 85 9.1E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_01845 dc61a21566a18dac879b2b9129ee05ee 257 SMART SM00346 12 102 8.9E-19 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UP12_01845 dc61a21566a18dac879b2b9129ee05ee 257 Gene3D G3DSA:3.30.450.40 86 253 1.1E-46 T 11-10-2018 IPR029016 GAF-like domain superfamily UP12_01845 dc61a21566a18dac879b2b9129ee05ee 257 Pfam PF01614 Bacterial transcriptional regulator 130 247 6.2E-20 T 11-10-2018 IPR014757 Transcription regulator IclR, C-terminal UP12_01845 dc61a21566a18dac879b2b9129ee05ee 257 Pfam PF09339 IclR helix-turn-helix domain 14 65 8.9E-13 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 UP12_08170 1b28aea3334bc89529a825cc72db404e 409 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 1.8E-48 T 11-10-2018 IPR011765 Peptidase M16, N-terminal UP12_08170 1b28aea3334bc89529a825cc72db404e 409 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 11-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 UP12_08170 1b28aea3334bc89529a825cc72db404e 409 SUPERFAMILY SSF63411 217 401 3.67E-45 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UP12_08170 1b28aea3334bc89529a825cc72db404e 409 Gene3D G3DSA:3.30.830.10 218 409 1.5E-53 T 11-10-2018 UP12_08170 1b28aea3334bc89529a825cc72db404e 409 Pfam PF05193 Peptidase M16 inactive domain 166 338 2.8E-37 T 11-10-2018 IPR007863 Peptidase M16, C-terminal UP12_08170 1b28aea3334bc89529a825cc72db404e 409 SUPERFAMILY SSF63411 3 204 4.02E-63 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 UP12_08170 1b28aea3334bc89529a825cc72db404e 409 Gene3D G3DSA:3.30.830.10 1 214 2.1E-82 T 11-10-2018 UP12_01710 10676240454fc66dedf0f85f0d487f65 476 Pfam PF03606 C4-dicarboxylate anaerobic carrier 18 469 8.6E-81 T 11-10-2018 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 UP12_13545 941f241e251d291ec86ed8d290f1cdd6 73 SUPERFAMILY SSF46785 10 59 2.54E-8 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_13545 941f241e251d291ec86ed8d290f1cdd6 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 54 5.8E-9 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_13545 941f241e251d291ec86ed8d290f1cdd6 73 SMART SM00420 11 56 0.0044 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 UP12_13545 941f241e251d291ec86ed8d290f1cdd6 73 Gene3D G3DSA:1.10.10.10 10 71 1.1E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_12865 f7a8db616fd650bb66b48b883306a28c 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 UP12_12865 f7a8db616fd650bb66b48b883306a28c 259 Gene3D G3DSA:3.90.226.10 2 259 1.7E-91 T 11-10-2018 UP12_12865 f7a8db616fd650bb66b48b883306a28c 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 258 5.8E-68 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 UP12_12865 f7a8db616fd650bb66b48b883306a28c 259 SUPERFAMILY SSF52096 6 259 6.91E-84 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_07255 fc6b0ae76b5cf27f147a1e2c6139dd1a 82 Pfam PF14003 YlbE-like protein 14 73 6.2E-26 T 11-10-2018 IPR025613 YlbE-like protein UP12_11895 440c3d50e414696c3a96887604af89df 231 SUPERFAMILY SSF53167 2 228 8.64E-73 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 UP12_11895 440c3d50e414696c3a96887604af89df 231 Gene3D G3DSA:3.40.50.1580 1 231 2.4E-71 T 11-10-2018 UP12_11895 440c3d50e414696c3a96887604af89df 231 Pfam PF01048 Phosphorylase superfamily 2 227 1.2E-51 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 UP12_11895 440c3d50e414696c3a96887604af89df 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 3.5E-120 T 11-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_11895 440c3d50e414696c3a96887604af89df 231 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.258 T 11-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 UP12_02990 cd5108191e3fe385c8a5c3e51eb6e773 207 Pfam PF00583 Acetyltransferase (GNAT) family 62 182 2.2E-7 T 11-10-2018 IPR000182 GNAT domain UP12_02990 cd5108191e3fe385c8a5c3e51eb6e773 207 Gene3D G3DSA:3.40.630.30 2 201 4.0E-22 T 11-10-2018 UP12_02990 cd5108191e3fe385c8a5c3e51eb6e773 207 SUPERFAMILY SSF55729 1 190 6.18E-19 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_02205 96ed0297d76b04043a80ae77b0953db3 144 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 142 4.6E-38 T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_02205 96ed0297d76b04043a80ae77b0953db3 144 SUPERFAMILY SSF55804 3 142 1.02E-43 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_02205 96ed0297d76b04043a80ae77b0953db3 144 Gene3D G3DSA:3.40.930.10 2 142 4.1E-47 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 UP12_02205 96ed0297d76b04043a80ae77b0953db3 144 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 48 64 - T 11-10-2018 IPR002178 PTS EIIA type-2 domain UP12_05745 812ee2e30381a2b4d741a75c15182cd8 385 PIRSF PIRSF007487 1 385 1.2E-71 T 11-10-2018 IPR021176 Competence-induced protein CoiA UP12_05745 812ee2e30381a2b4d741a75c15182cd8 385 Pfam PF06054 Competence protein CoiA-like family 1 365 3.0E-55 T 11-10-2018 IPR010330 Competence-induced protein CoiA-like UP12_10530 9e87cc6c94164dce0f70aa668902fb3b 338 PIRSF PIRSF011570 1 335 1.3E-165 T 11-10-2018 IPR010894 Stage V sporulation AD UP12_10530 9e87cc6c94164dce0f70aa668902fb3b 338 SUPERFAMILY SSF53901 57 312 3.46E-18 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 UP12_10530 9e87cc6c94164dce0f70aa668902fb3b 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 6 332 9.9E-164 T 11-10-2018 IPR010894 Stage V sporulation AD UP12_10530 9e87cc6c94164dce0f70aa668902fb3b 338 Gene3D G3DSA:3.40.47.40 1 338 1.5E-159 T 11-10-2018 IPR038369 Stage V sporulation AD superfamily UP12_10530 9e87cc6c94164dce0f70aa668902fb3b 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 332 7.8E-152 T 11-10-2018 IPR010894 Stage V sporulation AD UP12_17245 8b1cf6dad7a4d34e0a1164dc7c337cf6 184 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 6 184 21.534 T 11-10-2018 IPR022929 Putative manganese efflux pump MntP UP12_17245 8b1cf6dad7a4d34e0a1164dc7c337cf6 184 Pfam PF02659 Putative manganese efflux pump 34 181 1.1E-39 T 11-10-2018 IPR003810 Putative manganese efflux pump UP12_01825 dce28361604185126e79ef0114807274 126 Pfam PF07883 Cupin domain 48 117 1.3E-19 T 11-10-2018 IPR013096 Cupin 2, conserved barrel UP12_01825 dce28361604185126e79ef0114807274 126 Gene3D G3DSA:2.60.120.10 21 125 2.0E-25 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_01825 dce28361604185126e79ef0114807274 126 SUPERFAMILY SSF51182 16 119 4.21E-28 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_06665 a355b5aa441d2813d6b8a29a1883eb31 217 Gene3D G3DSA:2.40.10.420 182 216 1.2E-15 T 11-10-2018 UP12_06665 a355b5aa441d2813d6b8a29a1883eb31 217 Pfam PF07486 Cell Wall Hydrolase 118 215 1.4E-27 T 11-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 UP12_06665 a355b5aa441d2813d6b8a29a1883eb31 217 Gene3D G3DSA:1.10.10.2520 102 180 1.0E-28 T 11-10-2018 UP12_09865 9d019055a7879d37c34f5f0fd0a739df 223 Pfam PF13456 Reverse transcriptase-like 79 204 8.1E-14 T 11-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 UP12_09865 9d019055a7879d37c34f5f0fd0a739df 223 Gene3D G3DSA:3.30.420.10 75 214 4.6E-26 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_09865 9d019055a7879d37c34f5f0fd0a739df 223 SUPERFAMILY SSF53098 74 207 8.22E-21 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_08175 056d164e1bb7477a030691c8a01b4378 307 Pfam PF01636 Phosphotransferase enzyme family 25 240 9.2E-28 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase UP12_08175 056d164e1bb7477a030691c8a01b4378 307 Gene3D G3DSA:3.90.1200.10 99 295 3.6E-23 T 11-10-2018 UP12_08175 056d164e1bb7477a030691c8a01b4378 307 SUPERFAMILY SSF56112 6 259 9.62E-33 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_08365 e18e3e797f4e5ddd5f115d39a9ff406b 178 Gene3D G3DSA:2.60.40.3490 40 168 8.6E-49 T 11-10-2018 IPR038480 YuaB-like superfamily UP12_08365 e18e3e797f4e5ddd5f115d39a9ff406b 178 ProDom PD034110 YWEA MEMBRANE YUAB TRANSMEMBRANE ORF-1 13 166 1.0E-47 T 11-10-2018 IPR034650 YuaB-like UP12_07165 9f2d713b7337f4c52d2877945f5ea747 440 Gene3D G3DSA:3.40.50.1010 2 150 2.6E-23 T 11-10-2018 UP12_07165 9f2d713b7337f4c52d2877945f5ea747 440 Gene3D G3DSA:3.40.50.300 229 439 9.4E-70 T 11-10-2018 UP12_07165 9f2d713b7337f4c52d2877945f5ea747 440 SMART SM00670 3 135 1.2E-25 T 11-10-2018 IPR002716 PIN domain UP12_07165 9f2d713b7337f4c52d2877945f5ea747 440 SUPERFAMILY SSF52540 24 420 1.27E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_07165 9f2d713b7337f4c52d2877945f5ea747 440 Pfam PF13638 PIN domain 5 147 5.3E-35 T 11-10-2018 IPR002716 PIN domain UP12_07165 9f2d713b7337f4c52d2877945f5ea747 440 Pfam PF02562 PhoH-like protein 231 435 6.7E-54 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 SUPERFAMILY SSF52141 3 221 1.11E-94 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 Gene3D G3DSA:3.40.470.10 1 225 1.2E-100 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 7 214 1.2E-85 T 11-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 SMART SM00987 50 210 3.7E-36 T 11-10-2018 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 58 67 - T 11-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 6 221 40.719 T 11-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 SMART SM00986 50 210 3.7E-36 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UP12_17725 542e0889efe36afe4eaeaeef0aeef32b 226 Pfam PF03167 Uracil DNA glycosylase superfamily 55 209 9.0E-27 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 UP12_16630 ef4e42f8caa4acaef566f04631a11a48 251 Pfam PF00535 Glycosyl transferase family 2 8 150 8.8E-38 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_16630 ef4e42f8caa4acaef566f04631a11a48 251 Gene3D G3DSA:3.90.550.10 1 248 4.2E-62 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_16630 ef4e42f8caa4acaef566f04631a11a48 251 SUPERFAMILY SSF53448 5 225 1.41E-57 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_04640 7c0f4944546f8add6f4cbc992d044f6e 194 SUPERFAMILY SSF56037 19 185 2.62E-8 T 11-10-2018 UP12_16360 973c85d80c7b8fa990f7054de432f87d 363 Pfam PF13349 Putative adhesin 105 356 1.6E-17 T 11-10-2018 IPR025164 Putative adhesin UP12_16360 973c85d80c7b8fa990f7054de432f87d 363 PIRSF PIRSF012569 1 361 3.4E-121 T 11-10-2018 IPR016599 Uncharacterised conserved protein UCP012569 UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 Pfam PF03193 RsgA GTPase 63 230 1.7E-61 T 11-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 Pfam PF16745 RsgA N-terminal domain 3 60 6.8E-25 T 11-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 43 289 2.7E-90 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 SUPERFAMILY SSF50249 1 66 1.1E-17 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 295 38.336 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 Gene3D G3DSA:2.40.50.140 1 65 2.4E-30 T 11-10-2018 UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 Gene3D G3DSA:1.10.40.50 231 298 3.8E-23 T 11-10-2018 UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 Gene3D G3DSA:3.40.50.300 66 230 7.8E-49 T 11-10-2018 UP12_07685 1dd15b67031004bfbf21a13d4a70dbf6 298 SUPERFAMILY SSF52540 68 295 1.3E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_04980 75eba6d942f07e5131be8dcb3496fa4b 452 SUPERFAMILY SSF56059 224 424 4.04E-8 T 11-10-2018 UP12_04980 75eba6d942f07e5131be8dcb3496fa4b 452 Pfam PF14398 YheC/D like ATP-grasp 186 438 3.5E-74 T 11-10-2018 IPR026838 Endospore coat-associated protein YheC/D UP12_12010 44d055b912dc27166a651ed26fc0f9f8 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 214 5.9E-19 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_12010 44d055b912dc27166a651ed26fc0f9f8 216 SUPERFAMILY SSF161098 15 207 1.44E-41 T 11-10-2018 IPR035906 MetI-like superfamily UP12_12010 44d055b912dc27166a651ed26fc0f9f8 216 Gene3D G3DSA:1.10.3720.10 9 216 2.1E-49 T 11-10-2018 IPR035906 MetI-like superfamily UP12_12010 44d055b912dc27166a651ed26fc0f9f8 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 5.8E-29 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_03460 1ca794031cdf12b9f76c456924e4ec71 137 Pfam PF10049 Protein of unknown function (DUF2283) 5 54 4.6E-10 T 11-10-2018 IPR019270 Protein of unknown function DUF2283 UP12_03460 1ca794031cdf12b9f76c456924e4ec71 137 PIRSF PIRSF021389 2 120 1.7E-23 T 11-10-2018 IPR016789 Uncharacterised conserved protein UCP021389 UP12_10925 610cdd23235943b13c8e93f80cc59e12 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 235 7.9E-46 T 11-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UP12_10925 610cdd23235943b13c8e93f80cc59e12 245 SUPERFAMILY SSF51695 2 241 5.76E-72 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UP12_10925 610cdd23235943b13c8e93f80cc59e12 245 Gene3D G3DSA:3.20.20.190 1 244 1.6E-78 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UP12_13660 0cde68a85c82c98b67a54edd5aff87a5 107 Pfam PF14074 Protein of unknown function (DUF4257) 5 84 4.5E-35 T 11-10-2018 IPR025353 Protein of unknown function DUF4257) UP12_13660 0cde68a85c82c98b67a54edd5aff87a5 107 ProDom PD866859 YTVB PLASMID MEMBRANE TRANSMEMBRANE 1 107 8.0E-37 T 11-10-2018 UP12_08420 a22de2930cbfc8a795884d73ecd77a83 181 SUPERFAMILY SSF48498 100 178 2.71E-17 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_08420 a22de2930cbfc8a795884d73ecd77a83 181 Gene3D G3DSA:1.10.357.10 1 181 6.0E-45 T 11-10-2018 UP12_08420 a22de2930cbfc8a795884d73ecd77a83 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 2.6E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08420 a22de2930cbfc8a795884d73ecd77a83 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 9.0E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08420 a22de2930cbfc8a795884d73ecd77a83 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 9.0E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08420 a22de2930cbfc8a795884d73ecd77a83 181 SUPERFAMILY SSF46689 4 69 4.67E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_17960 fe6ffde6f1688e89886a6ac6205ff899 372 Pfam PF13407 Periplasmic binding protein domain 63 316 1.4E-34 T 11-10-2018 IPR025997 Periplasmic binding protein UP12_17960 fe6ffde6f1688e89886a6ac6205ff899 372 Gene3D G3DSA:3.40.50.2300 56 323 9.8E-77 T 11-10-2018 UP12_17960 fe6ffde6f1688e89886a6ac6205ff899 372 SUPERFAMILY SSF53822 53 333 2.04E-52 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_17960 fe6ffde6f1688e89886a6ac6205ff899 372 Gene3D G3DSA:3.40.50.2300 158 329 9.8E-77 T 11-10-2018 UP12_11620 f97470a79cef7d98a29100276ebbd00c 189 Gene3D G3DSA:3.40.140.10 2 149 7.1E-48 T 11-10-2018 UP12_11620 f97470a79cef7d98a29100276ebbd00c 189 SUPERFAMILY SSF53927 8 140 1.51E-40 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 UP12_11620 f97470a79cef7d98a29100276ebbd00c 189 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 UP12_11620 f97470a79cef7d98a29100276ebbd00c 189 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 151 1.4E-86 T 11-10-2018 IPR013404 Competence operon E, ComEB UP12_11620 f97470a79cef7d98a29100276ebbd00c 189 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 2.0E-28 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain UP12_11620 f97470a79cef7d98a29100276ebbd00c 189 PIRSF PIRSF006019 1 151 3.4E-61 T 11-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 UP12_16535 36569002ebb4e78ec13323ece65ba569 113 Gene3D G3DSA:3.30.160.170 9 109 7.0E-32 T 11-10-2018 IPR035924 FlaG-like superfamily UP12_16535 36569002ebb4e78ec13323ece65ba569 113 SUPERFAMILY SSF160214 15 112 2.88E-29 T 11-10-2018 IPR035924 FlaG-like superfamily UP12_16535 36569002ebb4e78ec13323ece65ba569 113 Pfam PF03646 FlaG protein 19 111 2.4E-26 T 11-10-2018 IPR005186 FlaG protein UP12_13845 06b0920fb30c2ef8eb7d12b2a5501fd3 74 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 3.0E-23 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UP12_13845 06b0920fb30c2ef8eb7d12b2a5501fd3 74 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 73 8.6E-38 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UP12_13845 06b0920fb30c2ef8eb7d12b2a5501fd3 74 Pfam PF01809 Haemolytic domain 2 68 6.3E-33 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UP12_13845 06b0920fb30c2ef8eb7d12b2a5501fd3 74 SMART SM01234 1 68 3.1E-50 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UP12_13845 06b0920fb30c2ef8eb7d12b2a5501fd3 74 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.089 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor UP12_08940 c72d099974a6d0f5e5d5c51349ffc759 255 Gene3D G3DSA:2.160.20.100 4 175 5.9E-20 T 11-10-2018 UP12_08940 c72d099974a6d0f5e5d5c51349ffc759 255 Pfam PF13599 Pentapeptide repeats (9 copies) 62 125 2.3E-9 T 11-10-2018 IPR001646 Pentapeptide repeat UP12_08940 c72d099974a6d0f5e5d5c51349ffc759 255 Pfam PF00805 Pentapeptide repeats (8 copies) 153 171 0.0049 T 11-10-2018 IPR001646 Pentapeptide repeat UP12_08940 c72d099974a6d0f5e5d5c51349ffc759 255 SUPERFAMILY SSF141571 22 172 3.79E-18 T 11-10-2018 UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 11 461 6.3E-172 T 11-10-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 Gene3D G3DSA:3.40.630.10 13 464 2.9E-171 T 11-10-2018 UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 Gene3D G3DSA:3.30.70.360 204 294 2.9E-171 T 11-10-2018 UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 SUPERFAMILY SSF55031 184 372 2.3E-47 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 Pfam PF01546 Peptidase family M20/M25/M40 84 462 7.2E-34 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 SUPERFAMILY SSF53187 9 465 2.73E-67 T 11-10-2018 UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 Gene3D G3DSA:3.30.70.360 184 380 2.9E-171 T 11-10-2018 UP12_13535 cbfdd9327d287fc7db53dd9ef2fe53f0 466 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 114 152 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 UP12_17940 8c34a4f0dc55f7b525e0214348ef5f29 363 Gene3D G3DSA:1.25.40.10 3 363 5.7E-78 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_17940 8c34a4f0dc55f7b525e0214348ef5f29 363 SUPERFAMILY SSF48452 124 269 1.71E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_17940 8c34a4f0dc55f7b525e0214348ef5f29 363 Pfam PF13374 Tetratricopeptide repeat 173 203 0.011 T 11-10-2018 UP12_15625 f0954944a53d2ba459284ec4d8efcd63 271 Pfam PF00005 ABC transporter 20 167 3.4E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15625 f0954944a53d2ba459284ec4d8efcd63 271 SMART SM00382 28 217 1.3E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15625 f0954944a53d2ba459284ec4d8efcd63 271 Gene3D G3DSA:3.40.50.300 3 256 6.5E-68 T 11-10-2018 UP12_15625 f0954944a53d2ba459284ec4d8efcd63 271 SUPERFAMILY SSF52540 4 230 3.62E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15625 f0954944a53d2ba459284ec4d8efcd63 271 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_03905 17589c1442f428333ca8c7cf33618f8d 216 Pfam PF03473 MOSC domain 54 161 4.6E-18 T 11-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 UP12_03905 17589c1442f428333ca8c7cf33618f8d 216 Pfam PF03475 3-alpha domain 174 215 4.1E-7 T 11-10-2018 IPR005163 3-alpha domain UP12_03905 17589c1442f428333ca8c7cf33618f8d 216 SUPERFAMILY SSF50800 8 215 5.75E-61 T 11-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily UP12_03905 17589c1442f428333ca8c7cf33618f8d 216 Gene3D G3DSA:2.40.33.20 2 216 2.0E-64 T 11-10-2018 UP12_07245 1c062c9e9e78157b2fea6b16f4ed4964 347 SUPERFAMILY SSF55797 225 342 1.26E-22 T 11-10-2018 IPR035940 CAP superfamily UP12_07245 1c062c9e9e78157b2fea6b16f4ed4964 347 Pfam PF14504 CAP-associated N-terminal 60 200 9.2E-53 T 11-10-2018 IPR029410 CAP-associated domain UP12_07245 1c062c9e9e78157b2fea6b16f4ed4964 347 Gene3D G3DSA:3.40.33.10 22 345 2.4E-107 T 11-10-2018 IPR035940 CAP superfamily UP12_07245 1c062c9e9e78157b2fea6b16f4ed4964 347 Pfam PF00188 Cysteine-rich secretory protein family 231 341 1.1E-17 T 11-10-2018 IPR014044 CAP domain UP12_13635 97968db23f3f1463a6d1705d469d2c0b 498 Gene3D G3DSA:3.40.190.10 155 494 2.1E-68 T 11-10-2018 UP12_13635 97968db23f3f1463a6d1705d469d2c0b 498 Gene3D G3DSA:3.40.190.10 61 410 2.1E-68 T 11-10-2018 UP12_13635 97968db23f3f1463a6d1705d469d2c0b 498 SUPERFAMILY SSF53850 23 496 4.18E-95 T 11-10-2018 UP12_13635 97968db23f3f1463a6d1705d469d2c0b 498 Pfam PF13416 Bacterial extracellular solute-binding protein 60 328 2.0E-16 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein UP12_17470 919eb6da1fd92f88d03cd1523e32a41f 172 Pfam PF08741 YwhD family 6 167 5.6E-83 T 11-10-2018 IPR014852 Uncharacterised protein YwhD UP12_02045 7da494fc7ac476e075d3d4e7fae6b79e 196 SUPERFAMILY SSF54593 2 147 1.3E-6 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_02045 7da494fc7ac476e075d3d4e7fae6b79e 196 Gene3D G3DSA:3.10.180.10 3 141 3.4E-6 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_15555 512c50bf4e08cff88242c7106820ef1e 289 Pfam PF13349 Putative adhesin 48 289 6.7E-53 T 11-10-2018 IPR025164 Putative adhesin UP12_13045 a70fec226ef13ee9ea8d9063df87c873 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 190 7.0E-65 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 UP12_13045 a70fec226ef13ee9ea8d9063df87c873 201 Gene3D G3DSA:3.40.50.300 1 201 3.5E-77 T 11-10-2018 UP12_13045 a70fec226ef13ee9ea8d9063df87c873 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 2 199 29.261 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 UP12_13045 a70fec226ef13ee9ea8d9063df87c873 201 SUPERFAMILY SSF52540 4 195 1.84E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13045 a70fec226ef13ee9ea8d9063df87c873 201 Pfam PF01121 Dephospho-CoA kinase 3 181 1.1E-63 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 UP12_00200 d62a75d26b61f6f59dde284b76c0999c 469 SUPERFAMILY SSF53383 3 354 1.03E-83 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_00200 d62a75d26b61f6f59dde284b76c0999c 469 SUPERFAMILY SSF55904 333 451 2.09E-18 T 11-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 UP12_00200 d62a75d26b61f6f59dde284b76c0999c 469 Gene3D G3DSA:3.40.640.10 45 275 4.1E-109 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_00200 d62a75d26b61f6f59dde284b76c0999c 469 Gene3D G3DSA:3.90.1150.150 276 365 4.1E-109 T 11-10-2018 UP12_00200 d62a75d26b61f6f59dde284b76c0999c 469 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 3 306 1.6E-87 T 11-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 UP12_00200 d62a75d26b61f6f59dde284b76c0999c 469 Gene3D G3DSA:3.90.105.10 401 454 9.7E-17 T 11-10-2018 UP12_00200 d62a75d26b61f6f59dde284b76c0999c 469 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 379 435 3.4E-11 T 11-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 UP12_11410 41f6226aef5bf6e966b2a0f3de45dd6c 314 Gene3D G3DSA:3.40.1010.20 104 197 8.4E-96 T 11-10-2018 UP12_11410 41f6226aef5bf6e966b2a0f3de45dd6c 314 Pfam PF02401 LytB protein 4 284 5.9E-81 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 UP12_11410 41f6226aef5bf6e966b2a0f3de45dd6c 314 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 4.1E-93 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 UP12_11410 41f6226aef5bf6e966b2a0f3de45dd6c 314 Gene3D G3DSA:3.40.50.11270 12 103 8.4E-96 T 11-10-2018 UP12_11410 41f6226aef5bf6e966b2a0f3de45dd6c 314 Gene3D G3DSA:3.40.1010.20 7 284 8.4E-96 T 11-10-2018 UP12_11410 41f6226aef5bf6e966b2a0f3de45dd6c 314 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.596 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 UP12_14635 fa09c915c2ef93048fc848b2b38f07b8 485 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 32 404 5.7E-116 T 11-10-2018 IPR006430 Phage portal protein PBSX family UP12_14635 fa09c915c2ef93048fc848b2b38f07b8 485 PIRSF PIRSF019260 4 484 2.6E-161 T 11-10-2018 IPR016753 Phage portal protein PBSX family, Firmicutes UP12_14635 fa09c915c2ef93048fc848b2b38f07b8 485 Pfam PF04860 Phage portal protein 122 445 3.7E-14 T 11-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein UP12_15965 b26605d7d7af1bb2a4d969670a60111b 71 SUPERFAMILY SSF158388 3 69 1.7E-34 T 11-10-2018 IPR037247 YvfG domain superfamily UP12_15965 b26605d7d7af1bb2a4d969670a60111b 71 Pfam PF09628 YvfG protein 3 69 8.9E-39 T 11-10-2018 IPR018590 Uncharacterised domain YvfG UP12_12035 756b39d54f81025ed827a1fade7e8766 372 SUPERFAMILY SSF52402 7 245 1.57E-58 T 11-10-2018 UP12_12035 756b39d54f81025ed827a1fade7e8766 372 Pfam PF03054 tRNA methyl transferase 9 359 7.1E-149 T 11-10-2018 UP12_12035 756b39d54f81025ed827a1fade7e8766 372 Gene3D G3DSA:2.30.30.280 214 277 3.2E-24 T 11-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 UP12_12035 756b39d54f81025ed827a1fade7e8766 372 Gene3D G3DSA:2.40.30.10 279 372 5.4E-28 T 11-10-2018 UP12_12035 756b39d54f81025ed827a1fade7e8766 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 360 40.721 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 UP12_12035 756b39d54f81025ed827a1fade7e8766 372 Gene3D G3DSA:3.40.50.620 1 213 2.3E-97 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_12035 756b39d54f81025ed827a1fade7e8766 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 359 1.6E-138 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 UP12_14950 7768dc594597b22c9d84bde0628c35e1 124 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 108 1.1E-35 T 11-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 UP12_14950 7768dc594597b22c9d84bde0628c35e1 124 Pfam PF03334 Na+/H+ antiporter subunit 12 93 8.1E-30 T 11-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 UP12_18610 27759d2bbcffd84869596d363ada93d8 392 SMART SM00028 129 162 22.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_18610 27759d2bbcffd84869596d363ada93d8 392 SMART SM00028 210 242 220.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_18610 27759d2bbcffd84869596d363ada93d8 392 SMART SM00028 170 203 11.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_18610 27759d2bbcffd84869596d363ada93d8 392 SUPERFAMILY SSF48452 89 312 4.87E-16 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_18610 27759d2bbcffd84869596d363ada93d8 392 Gene3D G3DSA:1.25.40.10 1 364 8.1E-80 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_11480 c255894df4e54b596f703946af9fbcc6 128 Gene3D G3DSA:1.10.3830.10 8 126 1.1E-41 T 11-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 UP12_11480 c255894df4e54b596f703946af9fbcc6 128 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 75 86 - T 11-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 UP12_11480 c255894df4e54b596f703946af9fbcc6 128 Pfam PF01219 Prokaryotic diacylglycerol kinase 22 122 1.0E-36 T 11-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 UP12_16310 6dc3be2f69a16154cc08c17ee2db8f33 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 85 178 3.3E-10 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UP12_16310 6dc3be2f69a16154cc08c17ee2db8f33 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 184 1.7E-54 T 11-10-2018 UP12_16310 6dc3be2f69a16154cc08c17ee2db8f33 216 SUPERFAMILY SSF56784 5 213 2.0E-58 T 11-10-2018 IPR036412 HAD-like superfamily UP12_16310 6dc3be2f69a16154cc08c17ee2db8f33 216 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 4 216 43.394 T 11-10-2018 IPR023733 Pyrophosphatase PpaX GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 UP12_16310 6dc3be2f69a16154cc08c17ee2db8f33 216 Gene3D G3DSA:1.10.150.240 21 83 6.4E-51 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 UP12_16310 6dc3be2f69a16154cc08c17ee2db8f33 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 120 184 1.9E-8 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 UP12_16310 6dc3be2f69a16154cc08c17ee2db8f33 216 Gene3D G3DSA:3.40.50.1000 9 188 6.4E-51 T 11-10-2018 IPR023214 HAD superfamily UP12_02855 514d3aa8aa794fe7162d0c3f7fc47c11 158 Gene3D G3DSA:2.30.30.840 2 67 5.8E-26 T 11-10-2018 UP12_02855 514d3aa8aa794fe7162d0c3f7fc47c11 158 Gene3D G3DSA:1.20.58.1290 68 158 8.8E-26 T 11-10-2018 UP12_02855 514d3aa8aa794fe7162d0c3f7fc47c11 158 SMART SM01058 6 116 3.8E-29 T 11-10-2018 IPR003711 CarD-like/TRCF domain UP12_02855 514d3aa8aa794fe7162d0c3f7fc47c11 158 Pfam PF02559 CarD-like/TRCF domain 7 115 3.3E-18 T 11-10-2018 IPR003711 CarD-like/TRCF domain UP12_02855 514d3aa8aa794fe7162d0c3f7fc47c11 158 SUPERFAMILY SSF141259 6 63 7.06E-13 T 11-10-2018 IPR036101 CarD-like/TRCF domain superfamily UP12_10055 c8890a7bd2508957fe72252b1108f651 279 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 263 42.831 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UP12_10055 c8890a7bd2508957fe72252b1108f651 279 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 264 5.9E-123 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UP12_10055 c8890a7bd2508957fe72252b1108f651 279 SUPERFAMILY SSF51621 3 263 1.7E-106 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 UP12_10055 c8890a7bd2508957fe72252b1108f651 279 Pfam PF02548 Ketopantoate hydroxymethyltransferase 6 258 1.3E-111 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UP12_10055 c8890a7bd2508957fe72252b1108f651 279 Gene3D G3DSA:3.20.20.60 2 272 4.7E-113 T 11-10-2018 UP12_10055 c8890a7bd2508957fe72252b1108f651 279 PIRSF PIRSF000388 1 266 8.7E-110 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 UP12_07465 de9bbcfa51b36093f45d07fc9101e027 118 SUPERFAMILY SSF141530 1 117 2.62E-34 T 11-10-2018 IPR036665 Phosphotransferase system, glucitol/sorbitol-specific IIA component superfamily GO:0005737|GO:0008982|GO:0009401 UP12_07465 de9bbcfa51b36093f45d07fc9101e027 118 Gene3D G3DSA:2.40.33.40 1 118 2.9E-33 T 11-10-2018 IPR036665 Phosphotransferase system, glucitol/sorbitol-specific IIA component superfamily GO:0005737|GO:0008982|GO:0009401 UP12_07465 de9bbcfa51b36093f45d07fc9101e027 118 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 4 115 9.1E-33 T 11-10-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 UP12_07465 de9bbcfa51b36093f45d07fc9101e027 118 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 2 116 2.0E-28 T 11-10-2018 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 Gene3D G3DSA:1.10.3860.10 1 419 2.3E-138 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 298 321 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 46 66 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 2 22 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 225 244 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 76 101 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 5.3E-48 T 11-10-2018 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 Pfam PF00375 Sodium:dicarboxylate symporter family 8 403 5.6E-127 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 SUPERFAMILY SSF118215 8 404 3.79E-123 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 UP12_05180 8adc6ce55532a7ad9bfa3c96240b0855 429 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 38 53 - T 11-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site UP12_15025 10aa58921dd9cccdb9a4bf2e3b855e62 78 Pfam PF10842 Protein of unknown function (DUF2642) 8 72 4.0E-31 T 11-10-2018 IPR020139 Protein of unknown function DUF2642 UP12_15025 10aa58921dd9cccdb9a4bf2e3b855e62 78 ProDom PD058323 YUZF BH2251 3 72 6.0E-21 T 11-10-2018 IPR020139 Protein of unknown function DUF2642 UP12_03520 9619bdbff7ec663f8bce20ee9931b5e7 89 SUPERFAMILY SSF47336 4 82 2.36E-12 T 11-10-2018 IPR036736 ACP-like superfamily UP12_03520 9619bdbff7ec663f8bce20ee9931b5e7 89 Pfam PF00550 Phosphopantetheine attachment site 5 76 4.9E-8 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain UP12_03520 9619bdbff7ec663f8bce20ee9931b5e7 89 Gene3D G3DSA:1.10.1200.10 1 85 6.8E-19 T 11-10-2018 IPR036736 ACP-like superfamily UP12_04385 54d12a71828656fc9c27acb42bd7f11a 176 Hamap MF_01568 UPF0374 protein . 1 175 49.739 T 11-10-2018 IPR016882 Uncharacterised protein family UPF0374 UP12_04385 54d12a71828656fc9c27acb42bd7f11a 176 SUPERFAMILY SSF159234 3 170 7.98E-34 T 11-10-2018 IPR035930 FomD-like superfamily UP12_04385 54d12a71828656fc9c27acb42bd7f11a 176 PIRSF PIRSF028345 1 176 7.8E-80 T 11-10-2018 IPR016882 Uncharacterised protein family UPF0374 UP12_04385 54d12a71828656fc9c27acb42bd7f11a 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 8.5E-18 T 11-10-2018 IPR007295 Domain of unknown function DUF402 UP12_04385 54d12a71828656fc9c27acb42bd7f11a 176 Gene3D G3DSA:2.40.380.10 14 169 9.1E-13 T 11-10-2018 IPR035930 FomD-like superfamily UP12_11610 dd87d3b4a4e867edfa8e5e130192bb76 44 Pfam PF14141 YqzM-like protein 2 43 8.4E-25 T 11-10-2018 IPR025416 YqzM-like protein UP12_10535 9fd8061a5dae3e8a00ff8555950fe77f 150 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 7 145 2.0E-65 T 11-10-2018 IPR014203 Sporulation stage V, protein AC UP12_10535 9fd8061a5dae3e8a00ff8555950fe77f 150 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 24 141 5.1E-41 T 11-10-2018 IPR005562 SpoVA UP12_06285 fcb09b46f26ed19c1eb957a63a14ec90 320 Gene3D G3DSA:1.10.3720.10 104 320 1.5E-22 T 11-10-2018 IPR035906 MetI-like superfamily UP12_06285 fcb09b46f26ed19c1eb957a63a14ec90 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 319 2.2E-30 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_06285 fcb09b46f26ed19c1eb957a63a14ec90 320 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 40 92 2.6E-17 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UP12_06285 fcb09b46f26ed19c1eb957a63a14ec90 320 SUPERFAMILY SSF161098 110 302 9.29E-28 T 11-10-2018 IPR035906 MetI-like superfamily UP12_10840 4e4d8ecba7a77928c80cf26bbd01601d 169 Gene3D G3DSA:2.40.440.10 8 168 1.5E-38 T 11-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UP12_10840 4e4d8ecba7a77928c80cf26bbd01601d 169 Pfam PF03734 L,D-transpeptidase catalytic domain 28 151 4.3E-20 T 11-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UP12_10840 4e4d8ecba7a77928c80cf26bbd01601d 169 SUPERFAMILY SSF141523 26 151 2.49E-31 T 11-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like UP12_12665 64e8dc1b184f6b898de3b83d9040f8d8 121 SMART SM00507 57 113 1.7E-6 T 11-10-2018 IPR003615 HNH nuclease UP12_12665 64e8dc1b184f6b898de3b83d9040f8d8 121 Pfam PF01844 HNH endonuclease 70 116 6.8E-12 T 11-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 UP12_06515 61629bb6955e98561c3102e64dd2326b 237 Pfam PF08876 Domain of unknown function (DUF1836) 64 159 2.5E-20 T 11-10-2018 IPR014975 Protein of unknown function DUF1836 UP12_01440 694a51cb809c0c064df4f0ae3dfdee95 160 SUPERFAMILY SSF49373 57 110 2.35E-5 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments UP12_01440 694a51cb809c0c064df4f0ae3dfdee95 160 Gene3D G3DSA:2.60.40.10 56 128 7.2E-7 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_08660 3db0803342ce8002c302c80f473d57a3 142 Pfam PF14040 Deoxyribonuclease NucA/NucB 45 134 2.6E-10 T 11-10-2018 IPR029476 Deoxyribonuclease NucA/NucB UP12_13765 627b7db485002f1e67aea8681714300f 375 Gene3D G3DSA:3.90.550.10 29 260 8.1E-32 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_13765 627b7db485002f1e67aea8681714300f 375 Pfam PF00535 Glycosyl transferase family 2 43 169 4.1E-21 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_13765 627b7db485002f1e67aea8681714300f 375 SUPERFAMILY SSF53448 35 293 4.78E-38 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_08825 c56a0648e9a933efe8485b5c6b72e5ec 139 Hamap MF_01624 Arsenate reductase [arsC]. 1 137 45.144 T 11-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 UP12_08825 c56a0648e9a933efe8485b5c6b72e5ec 139 SMART SM00226 4 137 1.0E-61 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UP12_08825 c56a0648e9a933efe8485b5c6b72e5ec 139 Gene3D G3DSA:3.40.50.2300 1 139 1.9E-59 T 11-10-2018 UP12_08825 c56a0648e9a933efe8485b5c6b72e5ec 139 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 135 1.1E-23 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UP12_08825 c56a0648e9a933efe8485b5c6b72e5ec 139 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 6 134 3.0E-71 T 11-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 UP12_08825 c56a0648e9a933efe8485b5c6b72e5ec 139 SUPERFAMILY SSF52788 4 136 7.2E-46 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily UP12_00115 364aec9efe88f19ea4e2fca8b7f27363 207 SUPERFAMILY SSF52540 1 205 4.88E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00115 364aec9efe88f19ea4e2fca8b7f27363 207 Pfam PF01712 Deoxynucleoside kinase 7 206 4.0E-56 T 11-10-2018 IPR031314 Deoxynucleoside kinase domain UP12_00115 364aec9efe88f19ea4e2fca8b7f27363 207 Gene3D G3DSA:3.40.50.300 5 207 4.5E-51 T 11-10-2018 UP12_00115 364aec9efe88f19ea4e2fca8b7f27363 207 PIRSF PIRSF000705 3 207 2.2E-60 T 11-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 UP12_18475 7d629665038e5fc0145393c4e4220f42 311 Gene3D G3DSA:3.90.245.10 1 311 8.4E-106 T 11-10-2018 IPR036452 Ribonucleoside hydrolase-like UP12_18475 7d629665038e5fc0145393c4e4220f42 311 SUPERFAMILY SSF53590 4 309 9.94E-94 T 11-10-2018 IPR036452 Ribonucleoside hydrolase-like UP12_18475 7d629665038e5fc0145393c4e4220f42 311 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 5 303 2.6E-90 T 11-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain UP12_03315 c685855a14c04844762b3a2945933d50 441 Pfam PF00860 Permease family 16 402 4.5E-44 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 UP12_03315 c685855a14c04844762b3a2945933d50 441 PIRSF PIRSF005353 1 441 3.8E-171 T 11-10-2018 IPR026033 Purine permease PbuG-like UP12_13590 97d742c5dbf3204822297559d3770c23 227 Pfam PF04854 Protein of unknown function, DUF624 20 96 8.4E-32 T 11-10-2018 IPR006938 Protein of unknown function DUF624 UP12_05540 61bb5b2228d0212608576cb10fec29da 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 237 2.8E-27 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 UP12_05540 61bb5b2228d0212608576cb10fec29da 270 Gene3D G3DSA:3.40.50.1000 8 264 1.1E-62 T 11-10-2018 IPR023214 HAD superfamily UP12_05540 61bb5b2228d0212608576cb10fec29da 270 SUPERFAMILY SSF56784 4 268 3.9E-66 T 11-10-2018 IPR036412 HAD-like superfamily UP12_05540 61bb5b2228d0212608576cb10fec29da 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 264 3.1E-66 T 11-10-2018 UP12_05540 61bb5b2228d0212608576cb10fec29da 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 264 1.4E-59 T 11-10-2018 IPR000150 Cof family GO:0016787 UP12_05540 61bb5b2228d0212608576cb10fec29da 270 Gene3D G3DSA:3.30.1240.10 87 193 1.1E-62 T 11-10-2018 UP12_10155 f1cba7604a91ffad6c6d3fef35941e34 267 Pfam PF00290 Tryptophan synthase alpha chain 7 245 6.0E-94 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_10155 f1cba7604a91ffad6c6d3fef35941e34 267 SUPERFAMILY SSF51366 6 238 1.51E-79 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_10155 f1cba7604a91ffad6c6d3fef35941e34 267 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 42 55 - T 11-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_10155 f1cba7604a91ffad6c6d3fef35941e34 267 Gene3D G3DSA:3.20.20.70 2 262 2.4E-93 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_10155 f1cba7604a91ffad6c6d3fef35941e34 267 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 7 260 1.5E-95 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_10155 f1cba7604a91ffad6c6d3fef35941e34 267 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 8 263 34.886 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_14485 734cea673374301e6830587ef6913621 208 Gene3D G3DSA:2.60.40.1240 73 206 1.8E-7 T 11-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily UP12_13095 768745fde2a174041b48de9614ef39a1 372 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 12 359 2.7E-102 T 11-10-2018 IPR014227 Putative transport protein YtvI-like UP12_13095 768745fde2a174041b48de9614ef39a1 372 Pfam PF01594 AI-2E family transporter 15 356 8.4E-63 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like UP12_17505 29d0798b47822d52987a1747895061f5 266 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 140 4.0E-44 T 11-10-2018 IPR014243 Transcription factor, RsfA UP12_05100 7aa5de491e421a789b1033a66c133ad8 172 Pfam PF17099 Tryptophan transporter TrpP 2 164 5.1E-55 T 11-10-2018 IPR031360 Tryptophan transporter TrpP UP12_05100 7aa5de491e421a789b1033a66c133ad8 172 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 166 2.0E-44 T 11-10-2018 UP12_05100 7aa5de491e421a789b1033a66c133ad8 172 Gene3D G3DSA:1.10.1760.20 1 168 1.1E-6 T 11-10-2018 UP12_07220 69289f6703db5eb7140ae276897dc8cf 206 Pfam PF00510 Cytochrome c oxidase subunit III 27 203 5.4E-18 T 11-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07220 69289f6703db5eb7140ae276897dc8cf 206 SUPERFAMILY SSF81452 21 203 1.96E-53 T 11-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07220 69289f6703db5eb7140ae276897dc8cf 206 Gene3D G3DSA:1.20.120.80 20 205 1.9E-49 T 11-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 Pfam PF00005 ABC transporter 356 501 5.2E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 Pfam PF00664 ABC transporter transmembrane region 20 292 2.2E-40 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 Gene3D G3DSA:1.20.1560.10 2 320 2.7E-74 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 Gene3D G3DSA:3.40.50.300 323 578 1.0E-81 T 11-10-2018 UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 SMART SM00382 363 549 4.7E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 SUPERFAMILY SSF90123 8 324 4.05E-70 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 UP12_04945 f0cacc4dc85a456b12f24bed615cd0d9 585 SUPERFAMILY SSF52540 329 573 1.88E-81 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15445 e9d4a1ca266ea28bda35a327847d6a06 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 117 1.6E-34 T 11-10-2018 IPR006504 Transcriptional regulator Spx/MgsR UP12_15445 e9d4a1ca266ea28bda35a327847d6a06 118 Gene3D G3DSA:3.40.30.10 1 116 2.8E-47 T 11-10-2018 UP12_15445 e9d4a1ca266ea28bda35a327847d6a06 118 Pfam PF03960 ArsC family 10 114 3.5E-18 T 11-10-2018 IPR006660 Arsenate reductase-like UP12_15445 e9d4a1ca266ea28bda35a327847d6a06 118 SUPERFAMILY SSF52833 5 117 2.93E-34 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_07505 21cc9a216b5798c0f02efc7457e50135 164 Pfam PF05103 DivIVA protein 3 133 2.9E-49 T 11-10-2018 IPR007793 DivIVA family UP12_07505 21cc9a216b5798c0f02efc7457e50135 164 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 2.5E-16 T 11-10-2018 IPR019933 DivIVA domain UP12_05310 9e52321c5405b8830917e73d83e6cfc3 148 Gene3D G3DSA:1.20.5.420 95 142 1.0E-10 T 11-10-2018 UP12_05310 9e52321c5405b8830917e73d83e6cfc3 148 Gene3D G3DSA:1.20.1260.10 17 86 9.6E-14 T 11-10-2018 IPR012347 Ferritin-like UP12_05310 9e52321c5405b8830917e73d83e6cfc3 148 Pfam PF02915 Rubrerythrin 23 79 9.1E-9 T 11-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 UP12_05310 9e52321c5405b8830917e73d83e6cfc3 148 SUPERFAMILY SSF47240 12 146 9.75E-31 T 11-10-2018 IPR009078 Ferritin-like superfamily UP12_07485 dc2505bab8fa013b00a865e8713495da 229 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 75 89 - T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UP12_07485 dc2505bab8fa013b00a865e8713495da 229 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 224 1.5E-56 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UP12_07485 dc2505bab8fa013b00a865e8713495da 229 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 224 28.748 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UP12_07485 dc2505bab8fa013b00a865e8713495da 229 PIRSF PIRSF004848 2 227 1.5E-69 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 UP12_07485 dc2505bab8fa013b00a865e8713495da 229 Gene3D G3DSA:3.20.20.10 1 227 1.8E-77 T 11-10-2018 IPR029066 PLP-binding barrel UP12_07485 dc2505bab8fa013b00a865e8713495da 229 Pfam PF01168 Alanine racemase, N-terminal domain 6 223 1.3E-19 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 UP12_07485 dc2505bab8fa013b00a865e8713495da 229 SUPERFAMILY SSF51419 2 223 2.45E-73 T 11-10-2018 IPR029066 PLP-binding barrel UP12_08440 a7da789cc0c6115ac4362b67de906747 73 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 64 29.964 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 UP12_08440 a7da789cc0c6115ac4362b67de906747 73 SUPERFAMILY SSF50182 5 63 3.89E-24 T 11-10-2018 IPR010920 LSM domain superfamily UP12_08440 a7da789cc0c6115ac4362b67de906747 73 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 5.8E-32 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 UP12_08440 a7da789cc0c6115ac4362b67de906747 73 Gene3D G3DSA:2.30.30.100 1 73 1.7E-35 T 11-10-2018 UP12_08440 a7da789cc0c6115ac4362b67de906747 73 Pfam PF17209 Hfq protein 6 68 3.6E-33 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 UP12_17445 82b22615df294d71ae90445272f96d3c 140 Gene3D G3DSA:2.40.128.20 1 139 1.7E-39 T 11-10-2018 IPR012674 Calycin UP12_17445 82b22615df294d71ae90445272f96d3c 140 SUPERFAMILY SSF50814 5 136 5.32E-32 T 11-10-2018 IPR012674 Calycin UP12_17445 82b22615df294d71ae90445272f96d3c 140 Pfam PF09148 Domain of unknown function (DUF1934) 8 132 7.2E-29 T 11-10-2018 IPR015231 Protein of unknown function DUF1934 UP12_04585 baa42e684380d94eb1ca25838b79246a 267 Pfam PF10020 Uncharacterized protein conserved in bacteria (DUF2262) 126 265 1.2E-43 T 11-10-2018 IPR019260 Domain of unknown function DUF2262 UP12_11095 71a808574ebee7507d2a34a72a379849 278 Gene3D G3DSA:3.30.930.10 4 278 1.6E-68 T 11-10-2018 UP12_11095 71a808574ebee7507d2a34a72a379849 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.203 T 11-10-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UP12_11095 71a808574ebee7507d2a34a72a379849 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 2.9E-30 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UP12_11095 71a808574ebee7507d2a34a72a379849 278 SUPERFAMILY SSF55681 5 278 8.29E-70 T 11-10-2018 UP12_03890 dab92856a2570bc51f38dedcf09019e2 185 SUPERFAMILY SSF46785 4 181 1.49E-39 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_03890 dab92856a2570bc51f38dedcf09019e2 185 Pfam PF10400 Virulence activator alpha C-term 94 180 9.2E-18 T 11-10-2018 IPR018309 Transcription regulator PadR, C-terminal UP12_03890 dab92856a2570bc51f38dedcf09019e2 185 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 3.2E-18 T 11-10-2018 IPR005149 Transcription regulator PadR, N-terminal UP12_03890 dab92856a2570bc51f38dedcf09019e2 185 Gene3D G3DSA:1.10.10.10 3 88 6.0E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 2.0E-32 T 11-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 SUPERFAMILY SSF54211 80 159 7.08E-26 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 1.5E-73 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 SUPERFAMILY SSF54768 8 76 5.34E-25 T 11-10-2018 UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 Gene3D G3DSA:3.30.230.10 74 166 1.2E-36 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.402 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 3.6E-30 T 11-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 11-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site UP12_00810 67d88bfa34f4188f097b02d5bf63e345 166 Gene3D G3DSA:3.30.160.20 1 73 1.5E-34 T 11-10-2018 UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 Gene3D G3DSA:1.10.10.10 21 145 2.9E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 Pfam PF01047 MarR family 51 93 5.9E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 SMART SM00347 32 129 5.2E-15 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 SUPERFAMILY SSF46785 36 143 4.97E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 2.9E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 2.9E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_05955 28ec6dd62134e34a19b12e72a5fd4c6c 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 2.9E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_15720 7542e5d6e55696198a0433224bb7db74 247 SUPERFAMILY SSF52540 4 225 5.43E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15720 7542e5d6e55696198a0433224bb7db74 247 SMART SM00382 29 234 4.3E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15720 7542e5d6e55696198a0433224bb7db74 247 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_15720 7542e5d6e55696198a0433224bb7db74 247 Gene3D G3DSA:3.40.50.300 1 241 1.4E-63 T 11-10-2018 UP12_15720 7542e5d6e55696198a0433224bb7db74 247 Pfam PF00005 ABC transporter 20 165 4.2E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_02980 551955914a5103a6aac40a660ebb60c0 179 Gene3D G3DSA:3.40.630.30 2 173 1.6E-43 T 11-10-2018 UP12_02980 551955914a5103a6aac40a660ebb60c0 179 SUPERFAMILY SSF55729 3 166 2.75E-40 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_02980 551955914a5103a6aac40a660ebb60c0 179 Pfam PF13302 Acetyltransferase (GNAT) domain 3 141 3.8E-22 T 11-10-2018 IPR000182 GNAT domain UP12_14270 393dec71b69c51d88ce4398995fe4584 301 Pfam PF04233 Phage Mu protein F like protein 157 277 4.8E-23 T 11-10-2018 IPR006528 Phage head morphogenesis domain UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 68 4.3E-25 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 PRINTS PR00942 Copper-transporting ATPase 1 signature 58 68 1.4E-8 T 11-10-2018 UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 PRINTS PR00942 Copper-transporting ATPase 1 signature 3 28 1.4E-8 T 11-10-2018 UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 PRINTS PR00942 Copper-transporting ATPase 1 signature 29 52 1.4E-8 T 11-10-2018 UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 Gene3D G3DSA:3.30.70.100 1 67 1.2E-24 T 11-10-2018 UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 Pfam PF00403 Heavy-metal-associated domain 5 66 1.3E-15 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 UP12_15770 07dcffc0bad9c40fb55aa0a892182997 68 SUPERFAMILY SSF55008 3 68 3.27E-19 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 UP12_09090 5de2aa69a497d0948be58f2ce043c377 161 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 138 3.2E-28 T 11-10-2018 IPR006750 Putative inner membrane exporter, YdcZ UP12_18885 c5390e3bc79bddc7bb14095db1e71783 459 Pfam PF07435 YycH protein 4 457 3.9E-118 T 11-10-2018 IPR009996 Regulatory protein YycH UP12_18885 c5390e3bc79bddc7bb14095db1e71783 459 Gene3D G3DSA:3.30.310.160 233 374 1.9E-63 T 11-10-2018 UP12_18885 c5390e3bc79bddc7bb14095db1e71783 459 Gene3D G3DSA:3.10.450.310 211 414 1.9E-63 T 11-10-2018 UP12_11225 b2d5384af1d2cf1220b75eeb523c19e4 57 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 1 57 4.0E-19 T 11-10-2018 IPR024490 Protein of unknown function DUF2759 UP12_11225 b2d5384af1d2cf1220b75eeb523c19e4 57 Pfam PF10958 Protein of unknown function (DUF2759) 6 56 1.7E-25 T 11-10-2018 IPR024490 Protein of unknown function DUF2759 UP12_02520 3f9f76943780023dd5e613776b53d54e 201 SUPERFAMILY SSF144091 12 197 2.22E-39 T 11-10-2018 UP12_02520 3f9f76943780023dd5e613776b53d54e 201 Pfam PF01694 Rhomboid family 54 191 2.4E-38 T 11-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 UP12_02520 3f9f76943780023dd5e613776b53d54e 201 Gene3D G3DSA:1.20.1540.10 8 199 8.7E-40 T 11-10-2018 IPR035952 Rhomboid-like superfamily UP12_14705 0873944b021f6b721c0ae3fc1ee66919 127 Pfam PF13564 DoxX-like family 10 79 7.7E-7 T 11-10-2018 IPR032808 DoxX family UP12_17195 55d63de13506b244ac0f0150079c6c18 181 Gene3D G3DSA:1.10.520.20 6 97 2.5E-13 T 11-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 PRINTS PR00125 ATP synthase delta subunit signature 6 25 3.4E-24 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 PRINTS PR00125 ATP synthase delta subunit signature 85 99 3.4E-24 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 PRINTS PR00125 ATP synthase delta subunit signature 136 151 3.4E-24 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 PRINTS PR00125 ATP synthase delta subunit signature 74 85 3.4E-24 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 PRINTS PR00125 ATP synthase delta subunit signature 151 169 3.4E-24 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 1.8E-52 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 SUPERFAMILY SSF47928 1 104 7.19E-23 T 11-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 19.319 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 3.7E-48 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_17195 55d63de13506b244ac0f0150079c6c18 181 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 11-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 UP12_15335 3c62a43c48bd29e058ad8fb3cc9cdfbb 399 Pfam PF04235 Protein of unknown function (DUF418) 223 385 1.7E-44 T 11-10-2018 IPR007349 Domain of unknown function DUF418 UP12_01665 3a28a87ef423f1ee5b00f0be48d05e41 271 SUPERFAMILY SSF56784 1 231 9.63E-17 T 11-10-2018 IPR036412 HAD-like superfamily UP12_01665 3a28a87ef423f1ee5b00f0be48d05e41 271 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 6 222 1.7E-4 T 11-10-2018 IPR006380 Sucrose-phosphatase-like, N-terminal UP12_01665 3a28a87ef423f1ee5b00f0be48d05e41 271 PIRSF PIRSF030802 1 237 8.2E-17 T 11-10-2018 IPR024197 Uncharacterised conserved protein UCP030802 UP12_01665 3a28a87ef423f1ee5b00f0be48d05e41 271 Gene3D G3DSA:3.40.50.1000 1 133 3.2E-16 T 11-10-2018 IPR023214 HAD superfamily UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 Gene3D G3DSA:1.10.10.10 1 85 2.4E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 SUPERFAMILY SSF46785 1 85 3.88E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.2E-22 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 Gene3D G3DSA:3.40.190.10 88 283 3.4E-58 T 11-10-2018 UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 Pfam PF03466 LysR substrate binding domain 88 289 3.3E-42 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 SUPERFAMILY SSF53850 91 291 4.6E-38 T 11-10-2018 UP12_16920 a5d8ef7cd304c1873c28787e32af9882 298 Gene3D G3DSA:3.40.190.10 162 267 3.4E-58 T 11-10-2018 UP12_10815 5c7db159ce21b198cb099be961fddf20 259 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 45 238 2.3E-51 T 11-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_10815 5c7db159ce21b198cb099be961fddf20 259 Pfam PF02096 60Kd inner membrane protein 45 238 3.5E-46 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_10815 5c7db159ce21b198cb099be961fddf20 259 PRINTS PR00701 60kDa inner membrane protein signature 205 228 6.7E-6 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_10815 5c7db159ce21b198cb099be961fddf20 259 PRINTS PR00701 60kDa inner membrane protein signature 116 139 6.7E-6 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 UP12_12195 9bccab63e53c55e0a1e0bf1f43b6ee05 369 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 23 368 7.3E-119 T 11-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UP12_12195 9bccab63e53c55e0a1e0bf1f43b6ee05 369 Gene3D G3DSA:3.40.50.10800 231 319 2.9E-80 T 11-10-2018 UP12_12195 9bccab63e53c55e0a1e0bf1f43b6ee05 369 Gene3D G3DSA:3.40.50.10800 113 366 2.9E-80 T 11-10-2018 UP12_12195 9bccab63e53c55e0a1e0bf1f43b6ee05 369 Gene3D G3DSA:3.40.50.10800 40 349 2.9E-80 T 11-10-2018 UP12_12195 9bccab63e53c55e0a1e0bf1f43b6ee05 369 Pfam PF02445 Quinolinate synthetase A protein 32 367 2.2E-104 T 11-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UP12_12195 9bccab63e53c55e0a1e0bf1f43b6ee05 369 SUPERFAMILY SSF142754 38 367 1.14E-94 T 11-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UP12_12195 9bccab63e53c55e0a1e0bf1f43b6ee05 369 Hamap MF_00569 Quinolinate synthase A [nadA]. 23 368 55.364 T 11-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 UP12_13300 74f375927aeb0e66db857a40ccd23a52 148 SUPERFAMILY SSF46785 15 140 9.23E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_13300 74f375927aeb0e66db857a40ccd23a52 148 Pfam PF01047 MarR family 33 90 3.6E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_13300 74f375927aeb0e66db857a40ccd23a52 148 Gene3D G3DSA:1.10.10.10 1 144 4.4E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_13300 74f375927aeb0e66db857a40ccd23a52 148 SMART SM00347 26 126 2.0E-18 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_07790 4ac978e1c0878f43d79a385e3d98b1e3 81 Pfam PF13083 KH domain 7 79 2.1E-21 T 11-10-2018 UP12_07790 4ac978e1c0878f43d79a385e3d98b1e3 81 Hamap MF_00088 UPF0109 protein . 6 80 21.355 T 11-10-2018 IPR020627 Uncharacterised protein family UPF0109 UP12_07790 4ac978e1c0878f43d79a385e3d98b1e3 81 SUPERFAMILY SSF54814 22 63 1.5E-6 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 UP12_07790 4ac978e1c0878f43d79a385e3d98b1e3 81 Gene3D G3DSA:3.30.300.20 5 67 6.9E-6 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta UP12_07305 d5bf9fddc6a7c0f6ad84042077867445 172 Pfam PF02620 Uncharacterized ACR, COG1399 56 165 6.6E-24 T 11-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD UP12_12440 d8ee8bc9553bea267c7174edae70eff3 347 SUPERFAMILY SSF51004 11 347 1.36E-46 T 11-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily UP12_12440 d8ee8bc9553bea267c7174edae70eff3 347 Gene3D G3DSA:2.130.10.10 4 347 8.6E-123 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_12440 d8ee8bc9553bea267c7174edae70eff3 347 Pfam PF10282 Lactonase, 7-bladed beta-propeller 6 345 5.7E-127 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 Gene3D G3DSA:2.30.33.40 1 93 2.9E-38 T 11-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 2.9E-36 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 SMART SM00883 1 93 3.1E-57 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 PRINTS PR00297 10kDa chaperonin signature 59 71 1.6E-32 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 PRINTS PR00297 10kDa chaperonin signature 2 17 1.6E-32 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 PRINTS PR00297 10kDa chaperonin signature 80 93 1.6E-32 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 PRINTS PR00297 10kDa chaperonin signature 24 45 1.6E-32 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 SUPERFAMILY SSF50129 1 93 8.95E-35 T 11-10-2018 IPR011032 GroES-like superfamily UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.18 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 UP12_03185 fd7cab16b5d5ed74b7c5ea86f62c83f7 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 11-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 UP12_10590 c8ec2ff4a1763a7328af4d3ed847d0cb 150 Pfam PF01475 Ferric uptake regulator family 15 136 9.1E-41 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 UP12_10590 c8ec2ff4a1763a7328af4d3ed847d0cb 150 Gene3D G3DSA:3.30.1490.190 93 149 3.0E-16 T 11-10-2018 UP12_10590 c8ec2ff4a1763a7328af4d3ed847d0cb 150 Gene3D G3DSA:1.10.10.10 1 88 6.2E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_10590 c8ec2ff4a1763a7328af4d3ed847d0cb 150 SUPERFAMILY SSF46785 7 141 8.84E-39 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_08060 7adb44c2d02bf8f35fa6285621dff472 260 Pfam PF01255 Putative undecaprenyl diphosphate synthase 38 258 1.4E-83 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UP12_08060 7adb44c2d02bf8f35fa6285621dff472 260 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 31 259 40.632 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UP12_08060 7adb44c2d02bf8f35fa6285621dff472 260 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 204 221 - T 11-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 UP12_08060 7adb44c2d02bf8f35fa6285621dff472 260 Gene3D G3DSA:3.40.1180.10 13 260 6.6E-100 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 UP12_08060 7adb44c2d02bf8f35fa6285621dff472 260 SUPERFAMILY SSF64005 29 253 4.58E-89 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 UP12_08060 7adb44c2d02bf8f35fa6285621dff472 260 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 31 258 2.8E-86 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 UP12_00405 bc0f9b5df2ff19efdfa6be3f5620bbeb 334 Pfam PF00069 Protein kinase domain 23 242 8.0E-16 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UP12_00405 bc0f9b5df2ff19efdfa6be3f5620bbeb 334 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 29 50 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 UP12_00405 bc0f9b5df2ff19efdfa6be3f5620bbeb 334 Gene3D G3DSA:3.30.200.20 16 105 4.2E-24 T 11-10-2018 UP12_00405 bc0f9b5df2ff19efdfa6be3f5620bbeb 334 SUPERFAMILY SSF56112 10 230 5.33E-24 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily UP12_00405 bc0f9b5df2ff19efdfa6be3f5620bbeb 334 Gene3D G3DSA:1.10.510.10 106 259 4.2E-24 T 11-10-2018 UP12_00405 bc0f9b5df2ff19efdfa6be3f5620bbeb 334 SMART SM00220 23 260 9.2E-7 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 UP12_18665 a22631af215feed28d48aa3d9bb11c6e 448 PIRSF PIRSF006060 1 448 3.9E-67 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_18665 a22631af215feed28d48aa3d9bb11c6e 448 Gene3D G3DSA:1.20.1740.10 4 448 5.1E-62 T 11-10-2018 UP12_18665 a22631af215feed28d48aa3d9bb11c6e 448 Pfam PF00324 Amino acid permease 14 440 1.1E-102 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_07265 b089217d67286d707125c66e9e9abfd5 149 Gene3D G3DSA:1.20.1500.10 3 126 3.8E-30 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily UP12_07265 b089217d67286d707125c66e9e9abfd5 149 SUPERFAMILY SSF158622 4 126 3.14E-34 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily UP12_07265 b089217d67286d707125c66e9e9abfd5 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 11 115 1.8E-21 T 11-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA UP12_01160 1e0bc191da90b5b35a41f729d086b5f0 141 Pfam PF13098 Thioredoxin-like domain 25 126 3.3E-11 T 11-10-2018 IPR012336 Thioredoxin-like fold UP12_01160 1e0bc191da90b5b35a41f729d086b5f0 141 Gene3D G3DSA:3.40.30.10 17 139 4.6E-20 T 11-10-2018 UP12_01160 1e0bc191da90b5b35a41f729d086b5f0 141 SUPERFAMILY SSF52833 23 137 5.39E-22 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 367 375 - T 11-10-2018 IPR018120 Glycoside hydrolase family 1, active site UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 SUPERFAMILY SSF51445 7 462 1.83E-170 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 Pfam PF00232 Glycosyl hydrolase family 1 11 468 5.9E-146 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 375 4.7E-17 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 4.7E-17 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 4.7E-17 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 4.7E-17 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 295 309 4.7E-17 T 11-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 UP12_10765 d263b64cdd989e0cbb07032a1fda81a5 468 Gene3D G3DSA:3.20.20.80 9 467 2.0E-160 T 11-10-2018 UP12_07160 e14686a233a7ecf75af03273aec17182 206 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 42 158 1.4E-16 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like UP12_07160 e14686a233a7ecf75af03273aec17182 206 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 9 160 2.4E-43 T 11-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 UP12_12710 037378d83cc34a85976d4ec17c35e6cf 292 Gene3D G3DSA:3.75.10.10 2 292 4.0E-66 T 11-10-2018 UP12_12710 037378d83cc34a85976d4ec17c35e6cf 292 SUPERFAMILY SSF55909 24 292 3.93E-46 T 11-10-2018 UP12_12710 037378d83cc34a85976d4ec17c35e6cf 292 Pfam PF02274 Amidinotransferase 74 291 1.6E-17 T 11-10-2018 UP12_19365 fd5d5af4748c3eee6e6392e2cc818731 120 SUPERFAMILY SSF46785 5 90 1.76E-13 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_19365 fd5d5af4748c3eee6e6392e2cc818731 120 Gene3D G3DSA:1.10.10.10 1 120 1.8E-37 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_19365 fd5d5af4748c3eee6e6392e2cc818731 120 ProDom PD077583 REPLICATION TRANSCRIPTION DNA-BINDING TERMINATOR REGULATION TERMINATION 3D-STRUCTURE 8 120 4.0E-18 T 11-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 UP12_19365 fd5d5af4748c3eee6e6392e2cc818731 120 Pfam PF02334 Replication terminator protein 3 120 1.3E-24 T 11-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 UP12_11925 ba06c0d8d71fb21733402e732805db96 115 Gene3D G3DSA:2.60.40.1080 23 115 5.9E-8 T 11-10-2018 UP12_11925 ba06c0d8d71fb21733402e732805db96 115 SUPERFAMILY SSF49373 48 114 2.41E-10 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments UP12_11925 ba06c0d8d71fb21733402e732805db96 115 Pfam PF02368 Bacterial Ig-like domain (group 2) 47 106 1.4E-13 T 11-10-2018 IPR003343 Bacterial Ig-like, group 2 UP12_15575 08faacfefa01df3873eb26647e7335cc 426 SUPERFAMILY SSF52540 2 230 1.3E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15575 08faacfefa01df3873eb26647e7335cc 426 Pfam PF00005 ABC transporter 18 167 1.1E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15575 08faacfefa01df3873eb26647e7335cc 426 SMART SM00382 26 215 1.5E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15575 08faacfefa01df3873eb26647e7335cc 426 Gene3D G3DSA:3.40.50.300 1 256 5.8E-70 T 11-10-2018 UP12_05915 2219b71566976c6c560a96d943411b2e 171 Gene3D G3DSA:3.90.1140.10 1 170 4.1E-43 T 11-10-2018 UP12_05915 2219b71566976c6c560a96d943411b2e 171 Hamap MF_01444 Putative phosphoesterase . 1 168 39.323 T 11-10-2018 IPR022932 Putative phosphoesterase YjcG UP12_05915 2219b71566976c6c560a96d943411b2e 171 SUPERFAMILY SSF55144 1 168 2.79E-34 T 11-10-2018 IPR009097 Cyclic phosphodiesterase UP12_05915 2219b71566976c6c560a96d943411b2e 171 Pfam PF13563 2'-5' RNA ligase superfamily 11 153 2.4E-24 T 11-10-2018 UP12_11275 b4d7b78807b61d978397cfbcf56b1c97 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 11-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 UP12_11275 b4d7b78807b61d978397cfbcf56b1c97 49 SUPERFAMILY SSF57829 1 49 2.75E-18 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 UP12_11275 b4d7b78807b61d978397cfbcf56b1c97 49 Gene3D G3DSA:2.20.28.120 1 49 2.8E-23 T 11-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11275 b4d7b78807b61d978397cfbcf56b1c97 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 2.5E-19 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11275 b4d7b78807b61d978397cfbcf56b1c97 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.943 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_11275 b4d7b78807b61d978397cfbcf56b1c97 49 Pfam PF00471 Ribosomal protein L33 3 49 1.0E-21 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_05345 791aed7521b18a806e56609106519b6d 144 Pfam PF10970 Spore germination protein GerPE 5 127 8.7E-54 T 11-10-2018 IPR024496 Spore germination protein GerPE UP12_05345 791aed7521b18a806e56609106519b6d 144 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 6 121 2.0E-25 T 11-10-2018 IPR024496 Spore germination protein GerPE UP12_03710 0fb444cded04c472e60ef401f33d02ca 359 Pfam PF13037 Domain of unknown function (DUF3898) 261 349 1.7E-39 T 11-10-2018 IPR025012 Domain of unknown function DUF3898 UP12_03710 0fb444cded04c472e60ef401f33d02ca 359 Pfam PF13039 Protein of unknown function (DUF3900) 2 254 2.2E-133 T 11-10-2018 IPR025006 Protein of unknown function DUF3900 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 Gene3D G3DSA:1.25.40.10 1 378 5.6E-117 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 Pfam PF13424 Tetratricopeptide repeat 219 293 3.2E-10 T 11-10-2018 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 SUPERFAMILY SSF48452 100 216 3.1E-7 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 SMART SM00028 180 213 110.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 SMART SM00028 262 295 22.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 SMART SM00028 99 132 200.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 SMART SM00028 220 253 7.3E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 SMART SM00028 139 172 360.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_06385 8ab41e41732991dc1ffa3471db640c2d 378 SUPERFAMILY SSF48452 187 292 6.07E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 SUPERFAMILY SSF51658 2 294 2.49E-101 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 Pfam PF01261 Xylose isomerase-like TIM barrel 22 237 8.4E-40 T 11-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 11-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 11-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 Gene3D G3DSA:3.20.20.150 1 297 3.8E-102 T 11-10-2018 UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 285 42.071 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 SMART SM00518 3 285 3.6E-130 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 282 5.0E-102 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 UP12_11395 ac364cf47d19baa7f64f9647dd912077 297 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 11-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.8E-15 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 SUPERFAMILY SSF46785 2 86 4.3E-17 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 Gene3D G3DSA:3.40.190.290 90 295 5.7E-41 T 11-10-2018 UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 SUPERFAMILY SSF53850 87 292 4.65E-42 T 11-10-2018 UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 Pfam PF03466 LysR substrate binding domain 87 289 5.9E-46 T 11-10-2018 IPR005119 LysR, substrate-binding UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 Gene3D G3DSA:1.10.10.10 1 89 5.3E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.5E-6 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.5E-6 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_11865 9bcf58aceefe3e3c28a0cafe109afba7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.5E-6 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 SMART SM00487 56 235 1.1E-29 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 Pfam PF00271 Helicase conserved C-terminal domain 360 463 1.5E-19 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 SUPERFAMILY SSF52540 14 259 2.49E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 SUPERFAMILY SSF52540 169 513 4.32E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 Gene3D G3DSA:3.40.50.10810 62 261 4.5E-42 T 11-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 SMART SM00490 383 463 1.9E-20 T 11-10-2018 IPR001650 Helicase, C-terminal UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 Pfam PF00176 SNF2 family N-terminal domain 79 300 8.5E-37 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 UP12_11120 2e17e44fe2a02488c6a0a765354180ea 556 Gene3D G3DSA:3.40.50.300 271 548 2.5E-52 T 11-10-2018 UP12_01260 62112272758af146adf4fa8f916a0746 337 SUPERFAMILY SSF50129 4 152 3.35E-35 T 11-10-2018 IPR011032 GroES-like superfamily UP12_01260 62112272758af146adf4fa8f916a0746 337 SMART SM00829 14 335 1.9E-13 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 UP12_01260 62112272758af146adf4fa8f916a0746 337 SUPERFAMILY SSF51735 121 244 5.52E-26 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_01260 62112272758af146adf4fa8f916a0746 337 Gene3D G3DSA:3.40.50.720 129 305 1.7E-77 T 11-10-2018 UP12_01260 62112272758af146adf4fa8f916a0746 337 Gene3D G3DSA:3.90.180.10 13 335 1.7E-77 T 11-10-2018 UP12_01260 62112272758af146adf4fa8f916a0746 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 92 4.5E-10 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 UP12_01260 62112272758af146adf4fa8f916a0746 337 Pfam PF13602 Zinc-binding dehydrogenase 191 335 3.9E-17 T 11-10-2018 UP12_07930 7a340408e35b6846e7a1bf71088b6e55 149 Pfam PF03963 Flagellar hook capping protein - N-terminal region 7 77 9.7E-23 T 11-10-2018 IPR005648 Flagellar hook capping protein UP12_04860 6df030cf191abc07ae4757410ab00005 277 Pfam PF00877 NlpC/P60 family 173 272 6.0E-28 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain UP12_04860 6df030cf191abc07ae4757410ab00005 277 Gene3D G3DSA:3.10.350.10 24 77 2.2E-15 T 11-10-2018 IPR036779 LysM domain superfamily UP12_04860 6df030cf191abc07ae4757410ab00005 277 Gene3D G3DSA:3.10.350.10 91 146 1.0E-18 T 11-10-2018 IPR036779 LysM domain superfamily UP12_04860 6df030cf191abc07ae4757410ab00005 277 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 41 - T 11-10-2018 IPR010916 TonB box, conserved site UP12_04860 6df030cf191abc07ae4757410ab00005 277 SUPERFAMILY SSF54106 26 70 1.83E-9 T 11-10-2018 UP12_04860 6df030cf191abc07ae4757410ab00005 277 SUPERFAMILY SSF54001 153 275 7.36E-35 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily UP12_04860 6df030cf191abc07ae4757410ab00005 277 Gene3D G3DSA:3.90.1720.10 151 277 4.7E-33 T 11-10-2018 UP12_04860 6df030cf191abc07ae4757410ab00005 277 Pfam PF01476 LysM domain 96 137 2.0E-13 T 11-10-2018 IPR018392 LysM domain UP12_04860 6df030cf191abc07ae4757410ab00005 277 Pfam PF01476 LysM domain 29 69 5.1E-13 T 11-10-2018 IPR018392 LysM domain UP12_04860 6df030cf191abc07ae4757410ab00005 277 SUPERFAMILY SSF54106 95 137 6.54E-11 T 11-10-2018 UP12_04860 6df030cf191abc07ae4757410ab00005 277 SMART SM00257 27 70 1.9E-13 T 11-10-2018 IPR018392 LysM domain UP12_04860 6df030cf191abc07ae4757410ab00005 277 SMART SM00257 95 138 4.3E-17 T 11-10-2018 IPR018392 LysM domain UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 Gene3D G3DSA:3.40.50.720 1 258 4.8E-65 T 11-10-2018 UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 SUPERFAMILY SSF51735 1 254 5.27E-68 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 Pfam PF00106 short chain dehydrogenase 7 189 3.7E-51 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_10710 7c21486caca5d84f0836654e66b8e2d2 258 PIRSF PIRSF000126 3 258 5.1E-53 T 11-10-2018 UP12_15440 c094c3c1a99301985ec3cac04347c553 127 SUPERFAMILY SSF51230 3 126 8.98E-47 T 11-10-2018 IPR011053 Single hybrid motif UP12_15440 c094c3c1a99301985ec3cac04347c553 127 Gene3D G3DSA:2.40.50.100 2 127 4.0E-53 T 11-10-2018 UP12_15440 c094c3c1a99301985ec3cac04347c553 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.59 T 11-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 UP12_15440 c094c3c1a99301985ec3cac04347c553 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 6.2E-61 T 11-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 UP12_15440 c094c3c1a99301985ec3cac04347c553 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 UP12_15440 c094c3c1a99301985ec3cac04347c553 127 Pfam PF01597 Glycine cleavage H-protein 7 126 2.2E-51 T 11-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 25 221 1.3E-92 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 1.0E-64 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 23 42 1.0E-64 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 1.0E-64 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 62 1.0E-64 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 1.0E-64 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 1.0E-64 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 21 30 3.3E-25 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 81 93 3.3E-25 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 93 107 3.3E-25 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 3.3E-25 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 3.3E-25 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 211 221 3.3E-25 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 Pfam PF00813 FliP family 25 217 8.7E-81 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_07970 ba5522647cd2967f4a88288fc8bde6ba 221 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 Gene3D G3DSA:1.20.210.10 30 561 4.4E-200 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 47 555 1.0E-202 T 11-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 501 5.1E-148 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 4 646 0.0 T 11-10-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 276 330 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 SUPERFAMILY SSF81442 44 555 1.57E-177 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 194 212 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 407 426 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 457 478 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 335 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 344 365 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 397 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 223 242 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_17810 5fb2cbc65a958a78205a554f8e0b19db 652 PRINTS PR01165 Cytochrome c oxidase subunit I signature 274 295 2.0E-104 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_18855 b9cc0c68ae5dca165687d82182c46356 229 Pfam PF12679 ABC-2 family transporter protein 2 229 2.9E-11 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UP12_10465 822ed42a369b8aaa07d4d83600f665b6 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 149 1.1E-59 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_10465 822ed42a369b8aaa07d4d83600f665b6 154 Gene3D G3DSA:3.40.50.960 1 154 6.0E-67 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_10465 822ed42a369b8aaa07d4d83600f665b6 154 SUPERFAMILY SSF52121 3 153 3.4E-64 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_10465 822ed42a369b8aaa07d4d83600f665b6 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 150 7.8E-61 T 11-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_10465 822ed42a369b8aaa07d4d83600f665b6 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 31.684 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 UP12_05530 8575e8b1a8c8ab02424e5cf334ce43fe 63 Pfam PF12758 Protein of unknown function (DUF3813) 2 63 3.4E-26 T 11-10-2018 IPR024217 Protein of unknown function DUF3813 UP12_04850 9c1c17359f5522ce12c8621bd1d8eac4 471 Pfam PF04293 SpoVR like protein 7 408 4.6E-162 T 11-10-2018 IPR007390 Sporulation stage V, protein R UP12_14230 749ebc4a6fc6482fae265ed3701b0965 151 ProDom PD033466 XKDJ PHAGE PHAGE-LIKE PBSX RELATED LIN1276 ELEMENT YQBJ 1 145 3.0E-41 T 11-10-2018 UP12_03400 3c39a4933ec6a1ca4ceeb1eb9e627182 281 Pfam PF00583 Acetyltransferase (GNAT) family 149 232 9.6E-7 T 11-10-2018 IPR000182 GNAT domain UP12_03400 3c39a4933ec6a1ca4ceeb1eb9e627182 281 Gene3D G3DSA:3.40.630.30 117 276 6.1E-16 T 11-10-2018 UP12_03400 3c39a4933ec6a1ca4ceeb1eb9e627182 281 TIGRFAM TIGR03827 GNAT_ablB: putative beta-lysine N-acetyltransferase 14 277 2.9E-90 T 11-10-2018 IPR022525 Beta-lysine N-acetyltransferase GO:0016407 UP12_03400 3c39a4933ec6a1ca4ceeb1eb9e627182 281 SUPERFAMILY SSF55729 127 277 8.65E-21 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_02790 c23d7c7f7a50b1c012acb6f871041522 764 SUPERFAMILY SSF81665 105 412 8.76E-5 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 UP12_07330 20f8232f182a80f83d5f44ca28bdb08a 539 PIRSF PIRSF012535 1 539 6.4E-194 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC UP12_07330 20f8232f182a80f83d5f44ca28bdb08a 539 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 539 31.485 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC UP12_07330 20f8232f182a80f83d5f44ca28bdb08a 539 Pfam PF10079 Bacillithiol biosynthesis BshC 1 536 1.3E-170 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC UP12_07330 20f8232f182a80f83d5f44ca28bdb08a 539 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 12 537 3.9E-178 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC UP12_19360 420cbb11e59b18c6159da072b0c8765f 447 Gene3D G3DSA:3.30.460.10 17 142 4.9E-8 T 11-10-2018 UP12_19360 420cbb11e59b18c6159da072b0c8765f 447 SUPERFAMILY SSF81301 16 160 1.83E-15 T 11-10-2018 UP12_13780 5adb7d9a5c27614a5c7d22a87ed0c8ba 333 Pfam PF09084 NMT1/THI5 like 44 257 1.1E-22 T 11-10-2018 IPR015168 SsuA/THI5-like UP12_13780 5adb7d9a5c27614a5c7d22a87ed0c8ba 333 Gene3D G3DSA:3.40.190.10 114 217 2.3E-52 T 11-10-2018 UP12_13780 5adb7d9a5c27614a5c7d22a87ed0c8ba 333 Gene3D G3DSA:3.40.190.10 38 306 2.3E-52 T 11-10-2018 UP12_13780 5adb7d9a5c27614a5c7d22a87ed0c8ba 333 SUPERFAMILY SSF53850 30 259 4.04E-34 T 11-10-2018 UP12_17865 a376d547bf6f4217d87578c4924486b0 222 Pfam PF13712 Glycosyltransferase like family 8 221 7.4E-83 T 11-10-2018 UP12_17865 a376d547bf6f4217d87578c4924486b0 222 Gene3D G3DSA:3.90.550.10 7 222 4.9E-39 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_12625 41e1a4ce892beabc326c89a38d206658 100 Gene3D G3DSA:1.10.3230.30 3 90 3.8E-5 T 11-10-2018 UP12_12625 41e1a4ce892beabc326c89a38d206658 100 Pfam PF05135 Phage gp6-like head-tail connector protein 8 83 2.4E-15 T 11-10-2018 IPR021146 Phage gp6-like head-tail connector protein UP12_12625 41e1a4ce892beabc326c89a38d206658 100 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 9 89 1.1E-15 T 11-10-2018 IPR006450 Phage protein of unkonwn function UP12_09955 d20b8d5825ef03bdcf72b8bbf1fb9ef2 415 SUPERFAMILY SSF48452 292 354 4.07E-5 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_09955 d20b8d5825ef03bdcf72b8bbf1fb9ef2 415 Pfam PF13482 RNase_H superfamily 109 277 4.0E-38 T 11-10-2018 IPR038720 YprB, ribonuclease H-like domain UP12_09955 d20b8d5825ef03bdcf72b8bbf1fb9ef2 415 SUPERFAMILY SSF53098 108 279 8.79E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_11385 a4ef31f5503364f2d22abd044acec24a 293 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 19 225 2.0E-64 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_11385 a4ef31f5503364f2d22abd044acec24a 293 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 231 285 8.9E-22 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 UP12_11385 a4ef31f5503364f2d22abd044acec24a 293 PIRSF PIRSF006483 1 292 9.5E-90 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_11385 a4ef31f5503364f2d22abd044acec24a 293 Gene3D G3DSA:3.30.70.120 203 278 4.4E-25 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_12135 f9c23bb2bcc09bb0ea2a9ad978236ff3 381 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 370 58.054 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 UP12_12135 f9c23bb2bcc09bb0ea2a9ad978236ff3 381 Gene3D G3DSA:3.20.20.105 3 375 5.7E-173 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 UP12_12135 f9c23bb2bcc09bb0ea2a9ad978236ff3 381 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 374 2.8E-178 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 UP12_12135 f9c23bb2bcc09bb0ea2a9ad978236ff3 381 SUPERFAMILY SSF51713 7 371 1.7E-162 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 UP12_12135 f9c23bb2bcc09bb0ea2a9ad978236ff3 381 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 1.4E-94 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 UP12_12135 f9c23bb2bcc09bb0ea2a9ad978236ff3 381 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 375 6.7E-190 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 UP12_11050 78e844664d95fedf654bfc29d02eec78 93 Pfam PF10942 Protein of unknown function (DUF2619) 19 87 1.8E-26 T 11-10-2018 IPR020390 Uncharacterised protein family YqhV UP12_11050 78e844664d95fedf654bfc29d02eec78 93 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 12 76 3.0E-16 T 11-10-2018 IPR020390 Uncharacterised protein family YqhV UP12_06010 43dc8fc4038ae4bc8933ed6bb7cbcd12 82 Pfam PF10852 Protein of unknown function (DUF2651) 7 76 9.6E-15 T 11-10-2018 IPR020258 Uncharacterised protein family YbeF UP12_06010 43dc8fc4038ae4bc8933ed6bb7cbcd12 82 ProDom PD060054 MEMBRANE SPANNING TRANSMEMBRANE YBEF 1 71 1.0E-6 T 11-10-2018 IPR020258 Uncharacterised protein family YbeF UP12_08605 c87d8feb87703ac716f058000fa7c57b 283 SUPERFAMILY SSF51735 3 232 2.8E-57 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08605 c87d8feb87703ac716f058000fa7c57b 283 Gene3D G3DSA:3.90.25.10 137 267 3.4E-86 T 11-10-2018 UP12_08605 c87d8feb87703ac716f058000fa7c57b 283 Pfam PF05368 NmrA-like family 4 217 2.1E-22 T 11-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 UP12_08605 c87d8feb87703ac716f058000fa7c57b 283 Gene3D G3DSA:3.40.50.720 4 266 3.4E-86 T 11-10-2018 UP12_15670 b582c08108cff84cb5e0aa86ee4e3039 616 Gene3D G3DSA:3.40.720.10 233 543 1.4E-73 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 UP12_15670 b582c08108cff84cb5e0aa86ee4e3039 616 SUPERFAMILY SSF53649 239 615 7.1E-71 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 UP12_15670 b582c08108cff84cb5e0aa86ee4e3039 616 Pfam PF00884 Sulfatase 241 533 2.9E-35 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 UP12_15670 b582c08108cff84cb5e0aa86ee4e3039 616 PIRSF PIRSF005091 1 616 2.3E-175 T 11-10-2018 IPR012160 Lipoteichoic acid synthase-like UP12_13280 5dff554135dbb7b1b047d46ae302b8f9 253 SMART SM00382 32 220 1.9E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_13280 5dff554135dbb7b1b047d46ae302b8f9 253 Pfam PF00005 ABC transporter 23 171 2.0E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_13280 5dff554135dbb7b1b047d46ae302b8f9 253 SUPERFAMILY SSF52540 3 225 8.83E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_13280 5dff554135dbb7b1b047d46ae302b8f9 253 Gene3D G3DSA:3.40.50.300 1 244 2.6E-65 T 11-10-2018 UP12_06950 dca4b29b473b0b6bbae419c296262135 368 Gene3D G3DSA:1.10.287.470 95 174 2.7E-41 T 11-10-2018 UP12_06950 dca4b29b473b0b6bbae419c296262135 368 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 46 249 1.5E-11 T 11-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain UP12_06950 dca4b29b473b0b6bbae419c296262135 368 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 37 367 1.3E-34 T 11-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 UP12_06950 dca4b29b473b0b6bbae419c296262135 368 Gene3D G3DSA:2.40.420.20 45 352 2.7E-41 T 11-10-2018 UP12_06950 dca4b29b473b0b6bbae419c296262135 368 Gene3D G3DSA:2.40.30.170 49 294 2.7E-41 T 11-10-2018 UP12_06950 dca4b29b473b0b6bbae419c296262135 368 SUPERFAMILY SSF111369 70 227 1.96E-5 T 11-10-2018 UP12_06950 dca4b29b473b0b6bbae419c296262135 368 Gene3D G3DSA:2.40.50.100 60 209 2.7E-41 T 11-10-2018 UP12_09860 706fa1d310bdf9782f61f917196bc4e5 60 Pfam PF10782 Zinc-finger 2 57 7.8E-29 T 11-10-2018 IPR019718 Protein of unknown function DUF2602 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 133 145 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 426 447 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 313 334 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 366 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 91 115 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 PRINTS PR01165 Cytochrome c oxidase subunit I signature 289 304 1.9E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 Gene3D G3DSA:1.20.210.10 2 530 7.1E-205 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 469 6.7E-147 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 245 299 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 SUPERFAMILY SSF81442 15 523 9.16E-180 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_07215 e943e77d81ce6c5bce71478a5e1cf674 623 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 18 521 8.3E-208 T 11-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UP12_18000 6c3d5a8c7f45f7024cfeb8a7e040cbb3 101 Gene3D G3DSA:3.40.50.2300 1 101 3.3E-37 T 11-10-2018 UP12_18000 6c3d5a8c7f45f7024cfeb8a7e040cbb3 101 SUPERFAMILY SSF52794 1 100 8.37E-36 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_18000 6c3d5a8c7f45f7024cfeb8a7e040cbb3 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 2 93 2.2E-22 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_18000 6c3d5a8c7f45f7024cfeb8a7e040cbb3 101 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 2 93 1.2E-37 T 11-10-2018 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 UP12_00615 1efe97e309a43666188c8720dec3aa64 217 Gene3D G3DSA:1.10.3130.10 2 67 1.8E-25 T 11-10-2018 UP12_00615 1efe97e309a43666188c8720dec3aa64 217 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 119 152 2.7E-6 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_00615 1efe97e309a43666188c8720dec3aa64 217 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 73 109 6.0E-4 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_00615 1efe97e309a43666188c8720dec3aa64 217 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 127 155 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UP12_00615 1efe97e309a43666188c8720dec3aa64 217 Gene3D G3DSA:2.160.10.10 68 186 3.7E-37 T 11-10-2018 UP12_00615 1efe97e309a43666188c8720dec3aa64 217 PIRSF PIRSF000441 1 217 1.0E-84 T 11-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 UP12_00615 1efe97e309a43666188c8720dec3aa64 217 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 7 167 6.2E-78 T 11-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 UP12_00615 1efe97e309a43666188c8720dec3aa64 217 SUPERFAMILY SSF51161 3 169 4.71E-55 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_00615 1efe97e309a43666188c8720dec3aa64 217 Pfam PF06426 Serine acetyltransferase, N-terminal 5 36 1.3E-4 T 11-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 UP12_13625 401f001b1965937b47b7956f6750fe13 395 Gene3D G3DSA:1.20.1250.20 200 394 1.1E-16 T 11-10-2018 UP12_13625 401f001b1965937b47b7956f6750fe13 395 Pfam PF07690 Major Facilitator Superfamily 13 325 2.5E-39 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_13625 401f001b1965937b47b7956f6750fe13 395 SUPERFAMILY SSF103473 3 386 2.49E-59 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_13625 401f001b1965937b47b7956f6750fe13 395 Gene3D G3DSA:1.20.1250.20 3 199 1.8E-30 T 11-10-2018 UP12_00870 266d3d665dbd1fdd9af3ce83f05834b4 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00870 266d3d665dbd1fdd9af3ce83f05834b4 120 Pfam PF01196 Ribosomal protein L17 16 120 1.6E-39 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00870 266d3d665dbd1fdd9af3ce83f05834b4 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 120 2.6E-49 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00870 266d3d665dbd1fdd9af3ce83f05834b4 120 SUPERFAMILY SSF64263 2 120 2.22E-45 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00870 266d3d665dbd1fdd9af3ce83f05834b4 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 28.803 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00870 266d3d665dbd1fdd9af3ce83f05834b4 120 Gene3D G3DSA:3.90.1030.10 1 120 5.9E-50 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_14320 507fac360d7933178e2dff18b4a1a447 114 SUPERFAMILY SSF49373 47 106 8.24E-5 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments UP12_14320 507fac360d7933178e2dff18b4a1a447 114 Gene3D G3DSA:2.60.40.10 30 114 4.2E-5 T 11-10-2018 IPR013783 Immunoglobulin-like fold UP12_09690 0f47278fbaf4b59c279ac759d8cadb4a 320 Pfam PF13524 Glycosyl transferases group 1 214 306 1.9E-12 T 11-10-2018 UP12_09690 0f47278fbaf4b59c279ac759d8cadb4a 320 Pfam PF12996 DUF based on E. rectale Gene description (DUF3880) 81 154 5.9E-13 T 11-10-2018 IPR024542 Domain of unknown function DUF3880 UP12_09690 0f47278fbaf4b59c279ac759d8cadb4a 320 SUPERFAMILY SSF53756 32 314 4.02E-6 T 11-10-2018 UP12_08755 80ef34225b69ad1c4462fa4c33fa57bc 167 Pfam PF00578 AhpC/TSA family 35 149 1.2E-29 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_08755 80ef34225b69ad1c4462fa4c33fa57bc 167 SUPERFAMILY SSF52833 31 165 3.09E-39 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_08755 80ef34225b69ad1c4462fa4c33fa57bc 167 Gene3D G3DSA:3.40.30.10 23 167 5.1E-45 T 11-10-2018 UP12_10220 68f620a271dd34787ad8b979b7838cf6 255 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 21 224 1.1E-76 T 11-10-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 UP12_09870 877175d4cd58a08c34f8dafe808306d9 229 Pfam PF02592 Putative vitamin uptake transporter 57 217 3.4E-49 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 UP12_09870 877175d4cd58a08c34f8dafe808306d9 229 Hamap MF_02088 Probable queuosine precursor transporter. 26 227 17.211 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 UP12_09870 877175d4cd58a08c34f8dafe808306d9 229 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 223 3.2E-74 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 UP12_14275 fbb16c6d786cb8190b1ef4f126b95d5b 509 PIRSF PIRSF019260 5 509 2.0E-164 T 11-10-2018 IPR016753 Phage portal protein PBSX family, Firmicutes UP12_14275 fbb16c6d786cb8190b1ef4f126b95d5b 509 Pfam PF04860 Phage portal protein 105 448 2.0E-13 T 11-10-2018 IPR006944 Bacteriophage/Gene transfer agent portal protein UP12_14275 fbb16c6d786cb8190b1ef4f126b95d5b 509 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 34 407 1.5E-117 T 11-10-2018 IPR006430 Phage portal protein PBSX family UP12_11155 bab7ee258dad9e5f991920c87f8b959d 64 Pfam PF14038 YqzE-like protein 2 54 8.6E-28 T 11-10-2018 IPR025622 YqzE-like protein UP12_04410 b6cb42e167f352507f59b468bdaa3769 333 SUPERFAMILY SSF161098 92 319 6.54E-20 T 11-10-2018 IPR035906 MetI-like superfamily UP12_04410 b6cb42e167f352507f59b468bdaa3769 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 9.6E-43 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_09415 d9b0f2951e7d2638929d6597959aca99 239 Gene3D G3DSA:3.60.15.10 8 237 1.6E-40 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_09415 d9b0f2951e7d2638929d6597959aca99 239 Pfam PF00753 Metallo-beta-lactamase superfamily 18 212 7.6E-31 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_09415 d9b0f2951e7d2638929d6597959aca99 239 SUPERFAMILY SSF56281 15 230 1.28E-43 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_09415 d9b0f2951e7d2638929d6597959aca99 239 SMART SM00849 20 212 2.4E-35 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_08020 76b90a3c9354dfb971c6fc9f3c1dc238 208 Pfam PF04509 CheC-like family 111 146 1.4E-11 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 UP12_08020 76b90a3c9354dfb971c6fc9f3c1dc238 208 Pfam PF04509 CheC-like family 10 46 3.4E-13 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 UP12_08020 76b90a3c9354dfb971c6fc9f3c1dc238 208 SUPERFAMILY SSF103039 5 206 4.71E-50 T 11-10-2018 IPR028976 CheC-like superfamily UP12_08020 76b90a3c9354dfb971c6fc9f3c1dc238 208 Gene3D G3DSA:3.40.1550.10 5 207 8.8E-58 T 11-10-2018 IPR028976 CheC-like superfamily UP12_14385 049961a30d8c73894abcfcfd658d5d70 67 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 7 59 3.0E-4 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA UP12_14385 049961a30d8c73894abcfcfd658d5d70 67 Pfam PF17356 Phage-like element PBSX protein XtrA 1 64 8.1E-11 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA UP12_05725 cbf594410d0ee2e1e93255f8d72ea56f 131 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 39.417 T 11-10-2018 IPR023731 Regulatory protein Spx GO:0045892 UP12_05725 cbf594410d0ee2e1e93255f8d72ea56f 131 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 6.5E-38 T 11-10-2018 IPR006504 Transcriptional regulator Spx/MgsR UP12_05725 cbf594410d0ee2e1e93255f8d72ea56f 131 SUPERFAMILY SSF52833 1 128 5.77E-41 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_05725 cbf594410d0ee2e1e93255f8d72ea56f 131 Gene3D G3DSA:3.40.30.10 1 131 5.5E-48 T 11-10-2018 UP12_05725 cbf594410d0ee2e1e93255f8d72ea56f 131 Pfam PF03960 ArsC family 5 113 5.5E-24 T 11-10-2018 IPR006660 Arsenate reductase-like UP12_06245 bff2ebdf186586997aac61a9af6739a2 318 Gene3D G3DSA:3.40.50.1360 56 316 6.9E-90 T 11-10-2018 UP12_06245 bff2ebdf186586997aac61a9af6739a2 318 SUPERFAMILY SSF100950 59 313 3.68E-74 T 11-10-2018 IPR037171 NagB/RpiA transferase-like UP12_06245 bff2ebdf186586997aac61a9af6739a2 318 Gene3D G3DSA:1.10.10.60 1 53 9.0E-22 T 11-10-2018 UP12_06245 bff2ebdf186586997aac61a9af6739a2 318 Pfam PF04198 Putative sugar-binding domain 60 313 1.0E-81 T 11-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 UP12_18375 126356e6fbe4dfd97d45c76de873d4dc 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 212 3.8E-96 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UP12_18375 126356e6fbe4dfd97d45c76de873d4dc 223 SMART SM01133 2 214 1.6E-106 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UP12_18375 126356e6fbe4dfd97d45c76de873d4dc 223 PIRSF PIRSF001357 1 222 4.9E-79 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UP12_18375 126356e6fbe4dfd97d45c76de873d4dc 223 Pfam PF01791 DeoC/LacD family aldolase 4 210 4.0E-22 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 UP12_18375 126356e6fbe4dfd97d45c76de873d4dc 223 Gene3D G3DSA:3.20.20.70 1 218 3.0E-97 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_18375 126356e6fbe4dfd97d45c76de873d4dc 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 37.678 T 11-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 UP12_18375 126356e6fbe4dfd97d45c76de873d4dc 223 SUPERFAMILY SSF51569 2 214 2.2E-83 T 11-10-2018 UP12_02130 75b66c0df413c7408eacfe32da84e677 444 Gene3D G3DSA:3.30.1330.120 267 400 7.9E-109 T 11-10-2018 UP12_02130 75b66c0df413c7408eacfe32da84e677 444 Gene3D G3DSA:1.10.4100.10 22 416 7.9E-109 T 11-10-2018 UP12_02130 75b66c0df413c7408eacfe32da84e677 444 SUPERFAMILY SSF103378 1 436 1.57E-93 T 11-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 UP12_02130 75b66c0df413c7408eacfe32da84e677 444 Pfam PF03972 MmgE/PrpD family 4 427 1.0E-92 T 11-10-2018 IPR005656 MmgE/PrpD GO:0016829 UP12_02495 b75094016dd364e35a5cbf464241d9a2 230 PIRSF PIRSF017388 1 230 4.0E-52 T 11-10-2018 IPR012354 Esterase/lipase GO:0052689 UP12_02495 b75094016dd364e35a5cbf464241d9a2 230 Pfam PF12146 Serine aminopeptidase, S33 7 213 7.1E-17 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 UP12_02495 b75094016dd364e35a5cbf464241d9a2 230 SUPERFAMILY SSF53474 5 228 2.26E-35 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02495 b75094016dd364e35a5cbf464241d9a2 230 Gene3D G3DSA:3.40.50.1820 3 228 2.4E-48 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_06215 ee56648e2a2e1f0799b1f62c927e649a 327 Pfam PF00676 Dehydrogenase E1 component 22 318 2.6E-89 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UP12_06215 ee56648e2a2e1f0799b1f62c927e649a 327 Gene3D G3DSA:3.40.50.970 2 327 1.9E-132 T 11-10-2018 UP12_06215 ee56648e2a2e1f0799b1f62c927e649a 327 SUPERFAMILY SSF52518 7 327 1.29E-105 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_02955 ea3a4fc8841e7dd91084538a802818af 725 SUPERFAMILY SSF82866 469 694 1.44E-29 T 11-10-2018 UP12_02955 ea3a4fc8841e7dd91084538a802818af 725 SUPERFAMILY SSF82866 141 333 1.01E-30 T 11-10-2018 UP12_02955 ea3a4fc8841e7dd91084538a802818af 725 Pfam PF03176 MMPL family 45 365 1.4E-69 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_02955 ea3a4fc8841e7dd91084538a802818af 725 Pfam PF03176 MMPL family 428 697 3.9E-40 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 UP12_02955 ea3a4fc8841e7dd91084538a802818af 725 Gene3D G3DSA:1.20.1640.10 167 356 5.0E-9 T 11-10-2018 UP12_15520 1412d92772b57e9a87bbd032ae04821e 474 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 20 467 1.6E-166 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_15520 1412d92772b57e9a87bbd032ae04821e 474 PIRSF PIRSF005690 2 472 1.7E-168 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_11330 714059d47dc0b4ee96342315f03cedd8 161 Pfam PF04306 Protein of unknown function (DUF456) 21 158 7.5E-38 T 11-10-2018 IPR007403 Protein of unknown function DUF456 UP12_08885 8f0095a24f3899fed756eae856dfba8a 124 Pfam PF01042 Endoribonuclease L-PSP 10 123 6.3E-27 T 11-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 UP12_08885 8f0095a24f3899fed756eae856dfba8a 124 Gene3D G3DSA:3.30.1330.40 2 124 4.2E-34 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_08885 8f0095a24f3899fed756eae856dfba8a 124 SUPERFAMILY SSF55298 11 124 6.13E-33 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 UP12_05505 e5bf646d3fcb45a23391c63fe427a19a 325 Gene3D G3DSA:3.40.50.2300 38 288 1.2E-90 T 11-10-2018 UP12_05505 e5bf646d3fcb45a23391c63fe427a19a 325 SUPERFAMILY SSF53822 45 247 1.16E-17 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_05505 e5bf646d3fcb45a23391c63fe427a19a 325 Gene3D G3DSA:3.40.50.2300 135 320 1.2E-90 T 11-10-2018 UP12_05505 e5bf646d3fcb45a23391c63fe427a19a 325 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 37 320 1.0E-71 T 11-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 UP12_10740 3a2d7fe013cb88ad1f38eb6ec8253fed 254 SUPERFAMILY SSF53474 5 236 1.44E-27 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_10740 3a2d7fe013cb88ad1f38eb6ec8253fed 254 Gene3D G3DSA:3.40.50.1820 7 240 3.8E-34 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_10740 3a2d7fe013cb88ad1f38eb6ec8253fed 254 Pfam PF00561 alpha/beta hydrolase fold 30 134 2.9E-13 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_13020 8b8c7aa511ff29f92847de5eb126f3c2 474 Pfam PF07261 Replication initiation and membrane attachment 333 395 1.0E-9 T 11-10-2018 IPR006343 DnaD domain UP12_13225 0b62517a65866a937c1e7904ca3ae55e 333 Gene3D G3DSA:3.90.226.10 60 274 2.9E-89 T 11-10-2018 UP12_13225 0b62517a65866a937c1e7904ca3ae55e 333 Gene3D G3DSA:3.40.1750.20 169 235 2.9E-89 T 11-10-2018 UP12_13225 0b62517a65866a937c1e7904ca3ae55e 333 SUPERFAMILY SSF52096 54 266 6.96E-41 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_13225 0b62517a65866a937c1e7904ca3ae55e 333 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 58 277 3.8E-85 T 11-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 UP12_13225 0b62517a65866a937c1e7904ca3ae55e 333 Pfam PF01343 Peptidase family S49 129 278 2.0E-58 T 11-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 UP12_02835 e4ff9f2e74b345749a99d95d988bd589 125 Pfam PF10049 Protein of unknown function (DUF2283) 4 56 8.9E-9 T 11-10-2018 IPR019270 Protein of unknown function DUF2283 UP12_02835 e4ff9f2e74b345749a99d95d988bd589 125 PIRSF PIRSF021389 2 125 3.6E-27 T 11-10-2018 IPR016789 Uncharacterised conserved protein UCP021389 UP12_09845 d41e53cb720721a4b9a13b4d6c6db32a 233 Gene3D G3DSA:3.60.160.10 15 228 2.5E-30 T 11-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily UP12_09845 d41e53cb720721a4b9a13b4d6c6db32a 233 Pfam PF01987 Mitochondrial biogenesis AIM24 27 221 3.8E-38 T 11-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 UP12_09845 d41e53cb720721a4b9a13b4d6c6db32a 233 SUPERFAMILY SSF51219 28 224 3.4E-54 T 11-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily UP12_18055 6089fb310e3fb3ef12ebd52263d08e38 338 PIRSF PIRSF000267 1 338 9.8E-116 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UP12_18055 6089fb310e3fb3ef12ebd52263d08e38 338 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 225 1.5E-90 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UP12_18055 6089fb310e3fb3ef12ebd52263d08e38 338 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 4 326 1.1E-106 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 UP12_13120 712fab290109737b94bcecbed42fb076 291 Pfam PF01039 Carboxyl transferase domain 63 242 4.8E-18 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 UP12_13120 712fab290109737b94bcecbed42fb076 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 144 7.8E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13120 712fab290109737b94bcecbed42fb076 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 252 261 7.8E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13120 712fab290109737b94bcecbed42fb076 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 164 182 7.8E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13120 712fab290109737b94bcecbed42fb076 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 230 241 7.8E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13120 712fab290109737b94bcecbed42fb076 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 201 218 7.8E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13120 712fab290109737b94bcecbed42fb076 291 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 4 282 38.485 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_13120 712fab290109737b94bcecbed42fb076 291 Gene3D G3DSA:3.90.226.10 29 283 1.7E-86 T 11-10-2018 UP12_13120 712fab290109737b94bcecbed42fb076 291 SUPERFAMILY SSF52096 29 284 2.81E-78 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_13120 712fab290109737b94bcecbed42fb076 291 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 7 283 1.0E-130 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 UP12_11615 aa05afba723b4d200bb784b403f02040 775 Pfam PF13567 Domain of unknown function (DUF4131) 27 165 1.8E-11 T 11-10-2018 IPR025405 Domain of unknown function DUF4131 UP12_11615 aa05afba723b4d200bb784b403f02040 775 Pfam PF00753 Metallo-beta-lactamase superfamily 507 718 4.2E-17 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_11615 aa05afba723b4d200bb784b403f02040 775 Gene3D G3DSA:3.60.15.10 499 763 3.0E-73 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_11615 aa05afba723b4d200bb784b403f02040 775 Pfam PF03772 Competence protein 207 468 1.9E-57 T 11-10-2018 IPR004477 ComEC/Rec2-related protein UP12_11615 aa05afba723b4d200bb784b403f02040 775 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 228 399 1.4E-35 T 11-10-2018 IPR004477 ComEC/Rec2-related protein UP12_11615 aa05afba723b4d200bb784b403f02040 775 SUPERFAMILY SSF56281 502 756 6.03E-52 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_11615 aa05afba723b4d200bb784b403f02040 775 SMART SM00849 510 721 2.5E-17 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_11615 aa05afba723b4d200bb784b403f02040 775 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 81 750 4.5E-146 T 11-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 UP12_14065 c52a7e434265337542605e0f904b4264 184 Pfam PF00583 Acetyltransferase (GNAT) family 38 136 2.7E-11 T 11-10-2018 IPR000182 GNAT domain UP12_14065 c52a7e434265337542605e0f904b4264 184 Gene3D G3DSA:3.40.630.30 1 166 6.5E-35 T 11-10-2018 UP12_14065 c52a7e434265337542605e0f904b4264 184 SUPERFAMILY SSF55729 1 136 1.58E-21 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_16730 9ba3ffba297e98a401233aa054ce746f 129 Gene3D G3DSA:3.40.50.620 1 129 4.5E-44 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_16730 9ba3ffba297e98a401233aa054ce746f 129 Pfam PF01467 Cytidylyltransferase-like 5 124 1.9E-23 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_16730 9ba3ffba297e98a401233aa054ce746f 129 TIGRFAM TIGR01518 g3p_cytidyltrns: glycerol-3-phosphate cytidylyltransferase 4 126 1.0E-67 T 11-10-2018 IPR006409 Glycerol-3-phosphate cytidylyltransferase GO:0005737|GO:0019350|GO:0046872|GO:0047348 KEGG: 00564+2.7.7.39|MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 UP12_16730 9ba3ffba297e98a401233aa054ce746f 129 SUPERFAMILY SSF52374 1 126 1.39E-35 T 11-10-2018 UP12_16730 9ba3ffba297e98a401233aa054ce746f 129 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 68 1.2E-21 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 UP12_15655 f99de9850973ac2aa5f6df26bf357bcc 47 TIGRFAM TIGR02863 spore_sspJ: small, acid-soluble spore protein, SspJ family 1 45 5.3E-16 T 11-10-2018 IPR014220 Small acid-soluble spore protein, SspJ UP12_15655 f99de9850973ac2aa5f6df26bf357bcc 47 Pfam PF09575 Small spore protein J (Spore_SspJ) 1 46 6.3E-29 T 11-10-2018 IPR014220 Small acid-soluble spore protein, SspJ UP12_18570 f92796badd70946603deb49ba1855394 379 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 375 4.9E-159 T 11-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UP12_18570 f92796badd70946603deb49ba1855394 379 Gene3D G3DSA:3.40.50.10350 2 358 7.4E-141 T 11-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold UP12_18570 f92796badd70946603deb49ba1855394 379 SUPERFAMILY SSF110738 1 375 6.15E-141 T 11-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 UP12_18570 f92796badd70946603deb49ba1855394 379 Gene3D G3DSA:3.90.1510.10 42 276 7.4E-141 T 11-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 UP12_18570 f92796badd70946603deb49ba1855394 379 Pfam PF02595 Glycerate kinase family 3 373 4.9E-149 T 11-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UP12_18570 f92796badd70946603deb49ba1855394 379 PIRSF PIRSF006078 1 378 6.9E-139 T 11-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 UP12_10450 d2893d2c35f0f9447e733003dd62c60d 252 Pfam PF02616 Segregation and condensation protein ScpA 21 244 7.8E-68 T 11-10-2018 IPR003768 Segregation and condensation protein A UP12_10450 d2893d2c35f0f9447e733003dd62c60d 252 Hamap MF_01805 Segregation and condensation protein A [scpA]. 4 247 27.392 T 11-10-2018 IPR003768 Segregation and condensation protein A UP12_08670 56baf9392a58f7d13dfaa697b8049b9a 180 Gene3D G3DSA:3.10.450.420 25 180 1.3E-54 T 11-10-2018 UP12_08670 56baf9392a58f7d13dfaa697b8049b9a 180 Pfam PF16800 IseA DL-endopeptidase inhibitor 29 178 2.0E-52 T 11-10-2018 IPR031841 DL-endopeptidase inhibitor IseA UP12_01865 f1e939cd394c814e4d5378101628d23a 457 Pfam PF00083 Sugar (and other) transporter 71 455 9.7E-51 T 11-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UP12_01865 f1e939cd394c814e4d5378101628d23a 457 SUPERFAMILY SSF103473 26 454 3.01E-85 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_01865 f1e939cd394c814e4d5378101628d23a 457 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 UP12_01865 f1e939cd394c814e4d5378101628d23a 457 Gene3D G3DSA:1.10.286.90 218 254 4.6E-8 T 11-10-2018 UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 Gene3D G3DSA:2.160.20.10 136 456 5.0E-58 T 11-10-2018 IPR012334 Pectin lyase fold UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 Pfam PF13229 Right handed beta helix region 406 573 1.2E-9 T 11-10-2018 IPR039448 Right handed beta helix domain UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 Pfam PF13229 Right handed beta helix region 241 385 2.2E-6 T 11-10-2018 IPR039448 Right handed beta helix domain UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 438 461 1200.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 308 335 540.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 408 431 580.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 365 386 300.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 342 364 7400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 509 531 84.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 462 484 810.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 533 563 2900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 260 290 6800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 236 259 1800.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SMART SM00710 485 507 3600.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SUPERFAMILY SSF51126 439 606 9.88E-11 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_12580 ae33b41682fbec82833ad4ef7e2b12c6 624 SUPERFAMILY SSF51126 136 450 1.82E-25 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_05205 f664ea08d3ef03509b2a7aad64ec196a 427 Gene3D G3DSA:3.30.2010.10 205 287 2.6E-27 T 11-10-2018 UP12_05205 f664ea08d3ef03509b2a7aad64ec196a 427 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 73 205 1.9E-16 T 11-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 UP12_05205 f664ea08d3ef03509b2a7aad64ec196a 427 Pfam PF01435 Peptidase family M48 209 416 3.2E-38 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 UP12_19675 a83cf1f2b92148461194571e174bcf05 400 Gene3D G3DSA:3.30.420.40 229 365 6.5E-12 T 11-10-2018 UP12_19675 a83cf1f2b92148461194571e174bcf05 400 SUPERFAMILY SSF53067 234 356 7.34E-7 T 11-10-2018 UP12_19675 a83cf1f2b92148461194571e174bcf05 400 Gene3D G3DSA:3.30.420.40 2 220 1.8E-10 T 11-10-2018 UP12_04430 d3d9ccfa6a73636be87c9d8ca79c895d 155 SUPERFAMILY SSF52833 3 154 2.59E-53 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_04430 d3d9ccfa6a73636be87c9d8ca79c895d 155 Pfam PF00578 AhpC/TSA family 5 132 1.1E-39 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_04430 d3d9ccfa6a73636be87c9d8ca79c895d 155 PIRSF PIRSF000239 1 154 1.5E-27 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_04430 d3d9ccfa6a73636be87c9d8ca79c895d 155 Gene3D G3DSA:3.40.30.10 2 155 8.0E-54 T 11-10-2018 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 Pfam PF11798 IMS family HHH motif 178 208 1.5E-7 T 11-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 SUPERFAMILY SSF56672 7 245 2.31E-46 T 11-10-2018 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 Gene3D G3DSA:3.30.1490.100 267 366 2.0E-11 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 Gene3D G3DSA:3.30.70.270 9 164 8.6E-24 T 11-10-2018 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 SUPERFAMILY SSF100879 272 358 8.63E-11 T 11-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 Gene3D G3DSA:2.30.40.20 27 79 8.6E-24 T 11-10-2018 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 Pfam PF00817 impB/mucB/samB family 11 160 7.3E-21 T 11-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 Pfam PF11799 impB/mucB/samB family C-terminal domain 254 362 3.7E-12 T 11-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 UP12_19385 8dd32eeb018e7ffada92f2a2563b9d60 421 Gene3D G3DSA:1.10.150.20 188 240 6.4E-16 T 11-10-2018 UP12_18930 e212d35b9e7be61526daca80c2463560 377 Pfam PF04235 Protein of unknown function (DUF418) 218 374 4.0E-43 T 11-10-2018 IPR007349 Domain of unknown function DUF418 UP12_08480 766502245294e43e687412d85be3a7cc 319 Gene3D G3DSA:1.10.8.60 226 316 4.4E-20 T 11-10-2018 UP12_08480 766502245294e43e687412d85be3a7cc 319 SUPERFAMILY SSF52540 40 304 2.88E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_08480 766502245294e43e687412d85be3a7cc 319 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 50 311 2.2E-138 T 11-10-2018 IPR014232 Sporulation stage V, protein K UP12_08480 766502245294e43e687412d85be3a7cc 319 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 94 225 2.7E-19 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 145 164 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 196 213 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 175 187 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 213 232 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 131 145 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 53 67 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 93 108 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 PRINTS PR00819 CbxX/CfqX superfamily signature 273 285 1.1E-61 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 UP12_08480 766502245294e43e687412d85be3a7cc 319 SMART SM00382 90 228 1.4E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_08480 766502245294e43e687412d85be3a7cc 319 Gene3D G3DSA:3.40.50.300 26 225 2.1E-57 T 11-10-2018 UP12_08965 c6f9793239c249f4813edafc6b18ec1a 102 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 99 3.0E-29 T 11-10-2018 UP12_08965 c6f9793239c249f4813edafc6b18ec1a 102 Pfam PF09685 Domain of unknown function (DUF4870) 5 95 2.1E-7 T 11-10-2018 IPR019109 Protein of unknown function DUF4870 UP12_12565 26e1fd96db0c196e8affdd693d2624da 139 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 10 134 5.8E-37 T 11-10-2018 IPR006480 Bacteriophage holin family UP12_12565 26e1fd96db0c196e8affdd693d2624da 139 Pfam PF05105 Bacteriophage holin family 18 125 3.4E-29 T 11-10-2018 IPR006480 Bacteriophage holin family UP12_03725 3bfea514c31008f89bb70e6f572f5783 303 Pfam PF03407 Nucleotide-diphospho-sugar transferase 37 197 2.7E-5 T 11-10-2018 IPR005069 Nucleotide-diphospho-sugar transferase UP12_03725 3bfea514c31008f89bb70e6f572f5783 303 SUPERFAMILY SSF53448 5 276 4.22E-16 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_07515 5614ca8882af2542a06a6503894949dd 124 Gene3D G3DSA:1.20.120.910 2 105 1.6E-12 T 11-10-2018 UP12_07515 5614ca8882af2542a06a6503894949dd 124 PIRSF PIRSF026544 1 123 1.1E-46 T 11-10-2018 IPR016841 Transcription regulator DksA-related, predicted UP12_15435 8b6dcb714d2bc8777b82e9d04773ef41 78 ProDom PD058325 YUSG BH3483 7 78 1.0E-18 T 11-10-2018 IPR020140 Uncharacterised protein family YusG UP12_15435 8b6dcb714d2bc8777b82e9d04773ef41 78 Pfam PF10830 Protein of unknown function (DUF2553) 6 78 1.8E-31 T 11-10-2018 IPR020140 Uncharacterised protein family YusG UP12_08280 fd46d9c450ca86c7a1f2a03245913088 303 Pfam PF13413 Helix-turn-helix domain 7 67 7.2E-22 T 11-10-2018 UP12_08280 fd46d9c450ca86c7a1f2a03245913088 303 SUPERFAMILY SSF47413 2 74 2.14E-8 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_08280 fd46d9c450ca86c7a1f2a03245913088 303 Pfam PF13464 Domain of unknown function (DUF4115) 218 279 1.4E-12 T 11-10-2018 IPR025194 Domain of unknown function DUF4115 UP12_08280 fd46d9c450ca86c7a1f2a03245913088 303 Gene3D G3DSA:1.10.260.40 1 101 1.9E-29 T 11-10-2018 UP12_08280 fd46d9c450ca86c7a1f2a03245913088 303 SMART SM00530 7 68 0.0022 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_08565 6eb2e114db0e6baf4571c2a6c6bb86f2 370 Gene3D G3DSA:1.25.40.10 1 369 2.2E-75 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_08565 6eb2e114db0e6baf4571c2a6c6bb86f2 370 Pfam PF13424 Tetratricopeptide repeat 174 244 1.1E-7 T 11-10-2018 UP12_08565 6eb2e114db0e6baf4571c2a6c6bb86f2 370 SUPERFAMILY SSF48452 105 252 4.88E-12 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_09210 96532365c23ed1377c56212dd047449d 383 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 215 380 3.2E-30 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_09210 96532365c23ed1377c56212dd047449d 383 Gene3D G3DSA:3.30.300.210 232 383 9.3E-15 T 11-10-2018 IPR038501 Spore germination GerAC superfamily UP12_09210 96532365c23ed1377c56212dd047449d 383 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 22 382 4.3E-79 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_19410 3c7a12d9be33593b8c8fc8af12c21de1 111 SUPERFAMILY SSF47413 3 73 7.78E-18 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_19410 3c7a12d9be33593b8c8fc8af12c21de1 111 Gene3D G3DSA:1.10.260.40 1 73 5.4E-20 T 11-10-2018 UP12_19410 3c7a12d9be33593b8c8fc8af12c21de1 111 Pfam PF01381 Helix-turn-helix 12 63 3.1E-15 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_19410 3c7a12d9be33593b8c8fc8af12c21de1 111 SMART SM00530 11 66 2.0E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_13090 30c1829b09dedd737f5d0065a725ba92 154 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 21 131 1.0E-37 T 11-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame UP12_13090 30c1829b09dedd737f5d0065a725ba92 154 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 3 149 18.656 T 11-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame UP12_13090 30c1829b09dedd737f5d0065a725ba92 154 Pfam PF04284 Protein of unknown function (DUF441) 7 146 2.3E-47 T 11-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame UP12_09580 0db9bb50a54ff2b9dcb55a72dce6e49c 304 SUPERFAMILY SSF103481 192 294 1.96E-9 T 11-10-2018 UP12_09580 0db9bb50a54ff2b9dcb55a72dce6e49c 304 SUPERFAMILY SSF103481 47 151 1.7E-10 T 11-10-2018 UP12_09580 0db9bb50a54ff2b9dcb55a72dce6e49c 304 TIGRFAM TIGR00688 rarD: protein RarD 11 268 9.1E-92 T 11-10-2018 IPR004626 RarD protein GO:0005887 UP12_09580 0db9bb50a54ff2b9dcb55a72dce6e49c 304 Pfam PF00892 EamA-like transporter family 160 291 2.6E-11 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_09580 0db9bb50a54ff2b9dcb55a72dce6e49c 304 Pfam PF00892 EamA-like transporter family 11 151 3.7E-12 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 UP12_10520 9038bf5b5b20c746c2b3cb13dd7b5a60 202 Pfam PF14097 Stage V sporulation protein AE1 6 185 6.4E-82 T 11-10-2018 IPR025914 Stage V sporulation protein AE UP12_00885 efeda4662119cbcfc1cd7e151c213af0 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 38.856 T 11-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 UP12_00885 efeda4662119cbcfc1cd7e151c213af0 265 Pfam PF02361 Cobalt transport protein 14 237 1.5E-57 T 11-10-2018 IPR003339 ABC/ECF transporter, transmembrane component UP12_13050 8290757914b3d8727d042f48f4f3a1b8 210 Pfam PF02659 Putative manganese efflux pump 4 82 1.2E-10 T 11-10-2018 IPR003810 Putative manganese efflux pump UP12_13050 8290757914b3d8727d042f48f4f3a1b8 210 Pfam PF02659 Putative manganese efflux pump 124 208 5.6E-11 T 11-10-2018 IPR003810 Putative manganese efflux pump UP12_13050 8290757914b3d8727d042f48f4f3a1b8 210 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 4 210 2.1E-77 T 11-10-2018 IPR014205 Sporulation protein YtaF UP12_14360 db989dedcb0c7978c55a121c8c22385b 151 SUPERFAMILY SSF159006 56 148 5.1E-6 T 11-10-2018 UP12_00225 46b3b2ad00eeb6eaf26ff32de46f6679 275 Pfam PF04468 PSP1 C-terminal conserved region 62 146 4.1E-31 T 11-10-2018 IPR007557 PSP1, C-terminal UP12_14900 3034cf80f7731aea2d7d002acdbc83d4 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 5.3E-47 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UP12_05710 defb65961403cce55f642c1ed3f9f992 306 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 276 5.7E-8 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 UP12_05710 defb65961403cce55f642c1ed3f9f992 306 SMART SM00382 34 228 2.4E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_05710 defb65961403cce55f642c1ed3f9f992 306 Gene3D G3DSA:3.40.50.300 3 305 5.0E-93 T 11-10-2018 UP12_05710 defb65961403cce55f642c1ed3f9f992 306 SUPERFAMILY SSF52540 5 250 4.36E-76 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05710 defb65961403cce55f642c1ed3f9f992 306 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_05710 defb65961403cce55f642c1ed3f9f992 306 Pfam PF00005 ABC transporter 26 178 2.0E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_00140 5e4f503d1f1b26a72dd86fa08454037b 107 SUPERFAMILY SSF82607 12 106 6.41E-35 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UP12_00140 5e4f503d1f1b26a72dd86fa08454037b 107 Pfam PF02575 YbaB/EbfC DNA-binding family 12 102 3.8E-35 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UP12_00140 5e4f503d1f1b26a72dd86fa08454037b 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 106 2.8E-36 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UP12_00140 5e4f503d1f1b26a72dd86fa08454037b 107 PIRSF PIRSF004555 4 107 5.7E-41 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UP12_00140 5e4f503d1f1b26a72dd86fa08454037b 107 Gene3D G3DSA:3.30.1310.10 2 107 6.3E-40 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily UP12_00140 5e4f503d1f1b26a72dd86fa08454037b 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 23.465 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family UP12_14115 0f03a35dce59a98f970284e4f3102b7c 375 SUPERFAMILY SSF48452 101 304 1.77E-19 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_14115 0f03a35dce59a98f970284e4f3102b7c 375 Pfam PF13424 Tetratricopeptide repeat 196 250 1.2E-8 T 11-10-2018 UP12_14115 0f03a35dce59a98f970284e4f3102b7c 375 Gene3D G3DSA:1.25.40.10 1 375 6.8E-124 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_14115 0f03a35dce59a98f970284e4f3102b7c 375 SMART SM00028 219 252 1.4E-6 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_14115 0f03a35dce59a98f970284e4f3102b7c 375 SMART SM00028 258 291 300.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_14115 0f03a35dce59a98f970284e4f3102b7c 375 SMART SM00028 138 171 58.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_14115 0f03a35dce59a98f970284e4f3102b7c 375 SMART SM00028 98 131 180.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 UP12_15920 79c6f72490a6695527afe516c63d86ea 253 Gene3D G3DSA:3.20.20.70 2 252 1.1E-103 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_15920 79c6f72490a6695527afe516c63d86ea 253 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 1.1E-58 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15920 79c6f72490a6695527afe516c63d86ea 253 SUPERFAMILY SSF51351 1 248 4.32E-93 T 11-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15920 79c6f72490a6695527afe516c63d86ea 253 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 60.37 T 11-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15920 79c6f72490a6695527afe516c63d86ea 253 Pfam PF00121 Triosephosphate isomerase 5 246 9.8E-94 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_15920 79c6f72490a6695527afe516c63d86ea 253 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 11-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 UP12_06100 e83e9dda27b90ad1125d2ee8482bf65e 204 Pfam PF14278 Transcriptional regulator C-terminal region 94 167 1.1E-8 T 11-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type UP12_06100 e83e9dda27b90ad1125d2ee8482bf65e 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 60 3.2E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_06100 e83e9dda27b90ad1125d2ee8482bf65e 204 Gene3D G3DSA:1.10.357.10 4 197 1.8E-37 T 11-10-2018 UP12_06100 e83e9dda27b90ad1125d2ee8482bf65e 204 SUPERFAMILY SSF46689 6 70 5.13E-15 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_12305 f101a48151549e3d4327ae81a4d6dee5 239 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 9 88 8.1E-26 T 11-10-2018 IPR010627 Peptidase A24A, N-terminal UP12_12305 f101a48151549e3d4327ae81a4d6dee5 239 Pfam PF01478 Type IV leader peptidase family 102 204 2.1E-14 T 11-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 UP12_04380 289acd0733e8d19094385f87dfedb46d 86 Pfam PF14182 YgaB-like protein 3 79 6.3E-30 T 11-10-2018 IPR025572 YgaB-like protein UP12_00570 10f4f69a735a0191cd8f58d560ed5f51 185 Pfam PF02151 UvrB/uvrC motif 143 176 3.2E-8 T 11-10-2018 IPR001943 UVR domain GO:0005515 UP12_00570 10f4f69a735a0191cd8f58d560ed5f51 185 SUPERFAMILY SSF46600 143 181 5.62E-7 T 11-10-2018 IPR036876 UVR domain superfamily UP12_00570 10f4f69a735a0191cd8f58d560ed5f51 185 PIRSF PIRSF015034 1 185 5.2E-70 T 11-10-2018 IPR025542 YacH protein UP12_06260 ea37df416869b6bc870a7a588492cb4a 318 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 154 275 1.4E-19 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_06260 ea37df416869b6bc870a7a588492cb4a 318 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 7.2E-12 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_06260 ea37df416869b6bc870a7a588492cb4a 318 Gene3D G3DSA:3.10.180.10 65 219 1.3E-117 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_06260 ea37df416869b6bc870a7a588492cb4a 318 Gene3D G3DSA:3.10.180.10 4 314 1.3E-117 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_06260 ea37df416869b6bc870a7a588492cb4a 318 SUPERFAMILY SSF54593 1 303 9.31E-55 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_01505 78a541a61d5548e6c609dfc7a78e303e 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 54 4.8E-14 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_01505 78a541a61d5548e6c609dfc7a78e303e 187 SUPERFAMILY SSF48498 75 182 4.5E-14 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_01505 78a541a61d5548e6c609dfc7a78e303e 187 SUPERFAMILY SSF46689 2 68 1.59E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_01505 78a541a61d5548e6c609dfc7a78e303e 187 Gene3D G3DSA:1.10.357.10 1 186 2.9E-52 T 11-10-2018 UP12_17655 79bee9d0190634a83ad48831f8e324b1 342 Gene3D G3DSA:3.40.50.2000 154 281 3.8E-24 T 11-10-2018 UP12_17655 79bee9d0190634a83ad48831f8e324b1 342 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 278 4.0E-7 T 11-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 UP12_17655 79bee9d0190634a83ad48831f8e324b1 342 Gene3D G3DSA:3.40.50.11190 3 150 1.3E-6 T 11-10-2018 UP12_17655 79bee9d0190634a83ad48831f8e324b1 342 SUPERFAMILY SSF53756 3 331 4.19E-16 T 11-10-2018 UP12_04325 9c1cad3795208dae341f2d2edbb77f05 377 Pfam PF01494 FAD binding domain 5 345 1.5E-27 T 11-10-2018 IPR002938 FAD-binding domain GO:0071949 UP12_04325 9c1cad3795208dae341f2d2edbb77f05 377 Gene3D G3DSA:3.50.50.60 4 374 2.6E-68 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_04325 9c1cad3795208dae341f2d2edbb77f05 377 SUPERFAMILY SSF51905 5 353 4.8E-51 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_04325 9c1cad3795208dae341f2d2edbb77f05 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 304 320 1.9E-19 T 11-10-2018 UP12_04325 9c1cad3795208dae341f2d2edbb77f05 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 1.9E-19 T 11-10-2018 UP12_04325 9c1cad3795208dae341f2d2edbb77f05 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 1.9E-19 T 11-10-2018 UP12_04325 9c1cad3795208dae341f2d2edbb77f05 377 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.9E-19 T 11-10-2018 UP12_10540 700925e4783fbcf2941f508e56b9915f 138 Pfam PF13782 Stage V sporulation protein AB 27 135 1.6E-35 T 11-10-2018 IPR020144 Stage V sporulation protein AB UP12_10540 700925e4783fbcf2941f508e56b9915f 138 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 27 138 2.0E-42 T 11-10-2018 IPR020144 Stage V sporulation protein AB UP12_19330 804605029e657658c1acd19605dc73e1 340 Pfam PF13155 Toprim-like 216 322 1.1E-10 T 11-10-2018 UP12_19330 804605029e657658c1acd19605dc73e1 340 SUPERFAMILY SSF57783 12 89 3.74E-8 T 11-10-2018 UP12_19330 804605029e657658c1acd19605dc73e1 340 Pfam PF13154 Protein of unknown function (DUF3991) 125 184 1.6E-14 T 11-10-2018 IPR025054 Domain of unknown function DUF3991 UP12_04025 f0aca71365c5c53272f4d7f82143943b 260 Pfam PF14167 YfkD-like protein 32 257 6.1E-110 T 11-10-2018 IPR025548 YfkD-like protein UP12_05340 e9f153b0788114dbfd9c59681da2ebcd 72 Pfam PF10676 Spore germination protein gerPA/gerPF 1 71 1.4E-28 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 390 8.4E-187 T 11-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 Gene3D G3DSA:3.40.50.1100 56 385 1.2E-181 T 11-10-2018 UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 11-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 379 4.3E-47 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 Gene3D G3DSA:3.40.50.1100 12 208 1.2E-181 T 11-10-2018 UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 SUPERFAMILY SSF53686 5 390 1.2E-140 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 PIRSF PIRSF001413 2 398 2.5E-164 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_10160 cd03a71bae7dad57a8301023a7c1de07 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 392 51.138 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 UP12_13775 04ab0993e78fbdea35f7d9a8023205f9 242 Pfam PF04240 Carotenoid biosynthesis protein 36 224 2.3E-33 T 11-10-2018 IPR007354 Carotene biosynthesis associated membrane protein UP12_14560 863aa0ee3f163e19f3e49053c77733af 140 Pfam PF10934 Protein of unknown function (DUF2634) 24 121 1.4E-25 T 11-10-2018 IPR020288 Protein of unknown function DUF2634 UP12_14560 863aa0ee3f163e19f3e49053c77733af 140 ProDom PD033094 XKDS PHAGE-LIKE PBSX ELEMENT PHAGE LIN1286 RELATED YQBS 24 136 6.0E-37 T 11-10-2018 IPR020288 Protein of unknown function DUF2634 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 Gene3D G3DSA:3.40.50.1980 214 327 2.3E-40 T 11-10-2018 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00691 Adhesin B signature 61 79 1.7E-9 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00691 Adhesin B signature 36 57 1.7E-9 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00691 Adhesin B signature 80 99 1.7E-9 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00691 Adhesin B signature 304 322 1.7E-9 T 11-10-2018 IPR006129 Adhesin B GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 Pfam PF01297 Zinc-uptake complex component A periplasmic 39 324 6.4E-72 T 11-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00690 Adhesin family signature 36 54 1.5E-6 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00690 Adhesin family signature 264 282 1.5E-6 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00690 Adhesin family signature 80 97 1.5E-6 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 PRINTS PR00690 Adhesin family signature 67 80 1.5E-6 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 Gene3D G3DSA:3.40.50.1980 25 213 8.4E-55 T 11-10-2018 UP12_13855 76046756a72115ce96d1b6b299a564c7 327 SUPERFAMILY SSF53807 35 326 7.36E-81 T 11-10-2018 UP12_02200 0ecdd3e92a38dde8956f964688275908 480 SUPERFAMILY SSF52794 391 480 9.29E-28 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_02200 0ecdd3e92a38dde8956f964688275908 480 Pfam PF02378 Phosphotransferase system, EIIC 20 278 1.5E-17 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_02200 0ecdd3e92a38dde8956f964688275908 480 Gene3D G3DSA:3.40.50.2300 379 480 6.0E-39 T 11-10-2018 UP12_02200 0ecdd3e92a38dde8956f964688275908 480 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 393 477 1.5E-13 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_02200 0ecdd3e92a38dde8956f964688275908 480 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 10 348 4.7E-178 T 11-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 UP12_12885 84a0f4958aaa3634f8e6377f86ba1939 134 Pfam PF03994 Domain of Unknown Function (DUF350) 80 134 3.6E-15 T 11-10-2018 IPR007140 Protein of unknown function DUF350 UP12_12885 84a0f4958aaa3634f8e6377f86ba1939 134 Pfam PF03994 Domain of Unknown Function (DUF350) 15 68 6.9E-13 T 11-10-2018 IPR007140 Protein of unknown function DUF350 UP12_10870 6fb2dc019baa1e68c1c6054b98277c7c 297 SUPERFAMILY SSF111331 4 296 1.83E-67 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily UP12_10870 6fb2dc019baa1e68c1c6054b98277c7c 297 Gene3D G3DSA:2.60.200.40 127 280 2.1E-76 T 11-10-2018 UP12_10870 6fb2dc019baa1e68c1c6054b98277c7c 297 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 128 3.6E-32 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UP12_10870 6fb2dc019baa1e68c1c6054b98277c7c 297 Gene3D G3DSA:3.40.50.10330 8 126 2.1E-76 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 UP12_10870 6fb2dc019baa1e68c1c6054b98277c7c 297 SMART SM00046 6 137 3.3E-20 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 UP12_10870 6fb2dc019baa1e68c1c6054b98277c7c 297 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 5 295 1.5E-91 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase UP12_09320 621147bf32b455ce372d230f8fe718bf 189 SUPERFAMILY SSF55729 11 155 1.73E-12 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_09320 621147bf32b455ce372d230f8fe718bf 189 Pfam PF00583 Acetyltransferase (GNAT) family 54 142 6.6E-7 T 11-10-2018 IPR000182 GNAT domain UP12_09320 621147bf32b455ce372d230f8fe718bf 189 Gene3D G3DSA:3.40.630.30 9 164 4.2E-10 T 11-10-2018 UP12_19635 d81ef4881cebea8164802dc6c8e20a0e 656 SUPERFAMILY SSF103647 606 649 4.18E-6 T 11-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 UP12_10315 022ab65161bf9e1dbb9ea844bfe3ae2e 218 Pfam PF13367 Protease prsW family 28 200 2.3E-33 T 11-10-2018 IPR026898 Protease PrsW GO:0008233 UP12_10315 022ab65161bf9e1dbb9ea844bfe3ae2e 218 PIRSF PIRSF016933 1 218 9.2E-90 T 11-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 UP12_14695 17ff0b10f11bd2a05fce8ba22a28850b 277 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 276 18.356 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UP12_14695 17ff0b10f11bd2a05fce8ba22a28850b 277 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 269 2.5E-101 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UP12_14695 17ff0b10f11bd2a05fce8ba22a28850b 277 Pfam PF02673 Bacitracin resistance protein BacA 9 271 8.2E-86 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 UP12_09420 dcdf95ce432aac54978b9e63d8c03884 157 SMART SM00871 2 146 2.5E-17 T 11-10-2018 IPR010499 Bacterial transcription activator, effector binding UP12_09420 dcdf95ce432aac54978b9e63d8c03884 157 Pfam PF14526 Integron-associated effector binding protein 4 145 4.1E-18 T 11-10-2018 IPR029441 Integron-associated effector binding protein UP12_09420 dcdf95ce432aac54978b9e63d8c03884 157 Gene3D G3DSA:3.20.80.10 1 146 2.4E-34 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_09420 dcdf95ce432aac54978b9e63d8c03884 157 SUPERFAMILY SSF55136 2 146 1.52E-16 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily UP12_11415 edc3ae93bde02cd9147a09994cd75a1c 373 Gene3D G3DSA:3.30.70.120 133 238 4.1E-38 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal UP12_11415 edc3ae93bde02cd9147a09994cd75a1c 373 SUPERFAMILY SSF102705 6 372 1.57E-130 T 11-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily UP12_11415 edc3ae93bde02cd9147a09994cd75a1c 373 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 351 6.5E-80 T 11-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 UP12_11415 edc3ae93bde02cd9147a09994cd75a1c 373 PIRSF PIRSF037489 3 373 1.1E-153 T 11-10-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria UP12_11415 edc3ae93bde02cd9147a09994cd75a1c 373 Gene3D G3DSA:3.40.1390.30 4 127 6.8E-41 T 11-10-2018 UP12_11415 edc3ae93bde02cd9147a09994cd75a1c 373 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 369 1.5E-103 T 11-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 UP12_01895 91baeca0d4016864ac70d8a859413343 267 Pfam PF10127 Predicted nucleotidyltransferase 13 259 6.4E-95 T 11-10-2018 IPR018775 Nucleotidyltransferase, predicted UP12_05700 9b05dbbda9e893df982d13beec9103b9 305 Gene3D G3DSA:1.10.3720.10 93 305 1.9E-22 T 11-10-2018 IPR035906 MetI-like superfamily UP12_05700 9b05dbbda9e893df982d13beec9103b9 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 305 9.2E-34 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_05700 9b05dbbda9e893df982d13beec9103b9 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 80 1.9E-15 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UP12_05700 9b05dbbda9e893df982d13beec9103b9 305 SUPERFAMILY SSF161098 99 286 2.75E-26 T 11-10-2018 IPR035906 MetI-like superfamily UP12_08725 e28f4b4939e09aab5bc8458c83545b1b 160 Pfam PF07301 Protein of unknown function (DUF1453) 5 147 1.5E-60 T 11-10-2018 IPR009916 Protein of unknown function DUF1453 UP12_08725 e28f4b4939e09aab5bc8458c83545b1b 160 PIRSF PIRSF021441 1 159 5.4E-70 T 11-10-2018 IPR031306 CcdC protein UP12_17860 3fd2dc080ab2de77957346a014cb9e52 229 SUPERFAMILY SSF53335 14 192 5.53E-36 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_17860 3fd2dc080ab2de77957346a014cb9e52 229 Pfam PF13489 Methyltransferase domain 34 180 2.8E-20 T 11-10-2018 UP12_17860 3fd2dc080ab2de77957346a014cb9e52 229 Gene3D G3DSA:3.40.50.150 20 227 5.8E-55 T 11-10-2018 UP12_01225 dc50af2d88a9d19a1305f4c104acdd6e 293 SUPERFAMILY SSF51695 37 288 6.28E-76 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UP12_01225 dc50af2d88a9d19a1305f4c104acdd6e 293 Gene3D G3DSA:3.20.20.190 26 292 9.7E-108 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 UP12_01225 dc50af2d88a9d19a1305f4c104acdd6e 293 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 43 284 1.0E-57 T 11-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 UP12_15315 1f892bd52e71f18f440b4c9b6647a907 303 SUPERFAMILY SSF53474 32 289 1.69E-39 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_15315 1f892bd52e71f18f440b4c9b6647a907 303 Pfam PF07859 alpha/beta hydrolase fold 73 272 3.8E-39 T 11-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UP12_15315 1f892bd52e71f18f440b4c9b6647a907 303 Gene3D G3DSA:3.40.50.1820 3 295 5.4E-73 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_05895 a4be2cb16e20c55522270af87fa9ae72 85 Pfam PF14069 Stage VI sporulation protein F 6 77 1.8E-27 T 11-10-2018 IPR025942 Stage VI sporulation protein F UP12_10750 b862cf53d2ae275dea4d1c51d6922f3b 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 305 4.3E-119 T 11-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 UP12_10750 b862cf53d2ae275dea4d1c51d6922f3b 309 Pfam PF12706 Beta-lactamase superfamily domain 201 270 3.4E-10 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_10750 b862cf53d2ae275dea4d1c51d6922f3b 309 Pfam PF12706 Beta-lactamase superfamily domain 35 149 2.7E-10 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_10750 b862cf53d2ae275dea4d1c51d6922f3b 309 Hamap MF_01818 Ribonuclease BN [rbn]. 1 305 42.344 T 11-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 UP12_10750 b862cf53d2ae275dea4d1c51d6922f3b 309 SUPERFAMILY SSF56281 1 306 1.68E-88 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_10750 b862cf53d2ae275dea4d1c51d6922f3b 309 Gene3D G3DSA:3.60.15.10 1 305 3.4E-110 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_15845 59cd2de00e44f9dde970727f6dd1590e 229 Gene3D G3DSA:1.10.3720.10 12 210 1.2E-33 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15845 59cd2de00e44f9dde970727f6dd1590e 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 212 2.3E-27 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_15845 59cd2de00e44f9dde970727f6dd1590e 229 SUPERFAMILY SSF161098 17 202 7.85E-37 T 11-10-2018 IPR035906 MetI-like superfamily UP12_01220 a87b164cef61781281fe37c9a2514c41 462 Gene3D G3DSA:1.20.1740.10 4 458 1.2E-56 T 11-10-2018 UP12_01220 a87b164cef61781281fe37c9a2514c41 462 Pfam PF00324 Amino acid permease 14 424 1.1E-102 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_01220 a87b164cef61781281fe37c9a2514c41 462 PIRSF PIRSF006060 1 460 8.3E-64 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_01220 a87b164cef61781281fe37c9a2514c41 462 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 11-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 UP12_17045 f80ac993fb651a2415a5e0b1fef30b60 220 Gene3D G3DSA:1.10.3720.10 6 218 3.1E-57 T 11-10-2018 IPR035906 MetI-like superfamily UP12_17045 f80ac993fb651a2415a5e0b1fef30b60 220 SUPERFAMILY SSF161098 16 201 2.09E-47 T 11-10-2018 IPR035906 MetI-like superfamily UP12_17045 f80ac993fb651a2415a5e0b1fef30b60 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 110 2.4E-27 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 UP12_17045 f80ac993fb651a2415a5e0b1fef30b60 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 216 6.9E-24 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_18305 bf8b1ce32926443236b95c14449db4a5 244 Pfam PF02361 Cobalt transport protein 6 217 1.1E-37 T 11-10-2018 IPR003339 ABC/ECF transporter, transmembrane component UP12_12125 e9e70b341ae3e4e71bc2cdbbd30357c1 125 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 10 122 3.2E-29 T 11-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane UP12_12125 e9e70b341ae3e4e71bc2cdbbd30357c1 125 Pfam PF12670 Protein of unknown function (DUF3792) 9 119 2.7E-22 T 11-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 Gene3D G3DSA:3.40.50.300 1 280 1.9E-58 T 11-10-2018 UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 SUPERFAMILY SSF52540 6 237 4.39E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 Pfam PF00005 ABC transporter 18 184 8.9E-22 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 Pfam PF00005 ABC transporter 335 468 2.9E-13 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 SMART SM00382 26 228 5.5E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 SMART SM00382 344 512 1.1 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 Gene3D G3DSA:3.40.50.300 283 536 1.8E-40 T 11-10-2018 UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 SUPERFAMILY SSF52540 296 525 5.26E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_06990 7e1a7beb51c755b46de6c3f7413833c2 539 Pfam PF12848 ABC transporter 224 309 6.5E-21 T 11-10-2018 IPR032781 ABC-transporter extension domain UP12_11255 745fa89682fe48827091f77d2e916f6e 67 SUPERFAMILY SSF158379 1 59 1.31E-21 T 11-10-2018 IPR023164 YqgQ-like superfamily UP12_11255 745fa89682fe48827091f77d2e916f6e 67 Gene3D G3DSA:1.10.287.760 1 67 5.7E-25 T 11-10-2018 IPR023164 YqgQ-like superfamily UP12_11255 745fa89682fe48827091f77d2e916f6e 67 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 59 3.0E-27 T 11-10-2018 IPR009256 Protein of unknown function DUF910 UP12_04765 b2d8f2eee349ac1c3cf70c8fb8711f6a 138 Gene3D G3DSA:3.10.180.10 1 136 8.5E-52 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_04765 b2d8f2eee349ac1c3cf70c8fb8711f6a 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 127 2.8E-6 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_04765 b2d8f2eee349ac1c3cf70c8fb8711f6a 138 SUPERFAMILY SSF54593 9 132 1.51E-22 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_01925 641c727b679cbd76802ed3b57064e993 290 Gene3D G3DSA:3.40.190.10 46 268 1.0E-77 T 11-10-2018 UP12_01925 641c727b679cbd76802ed3b57064e993 290 SMART SM00062 47 273 5.7E-67 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_01925 641c727b679cbd76802ed3b57064e993 290 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 271 1.8E-53 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_01925 641c727b679cbd76802ed3b57064e993 290 SUPERFAMILY SSF53850 10 271 2.15E-58 T 11-10-2018 UP12_01925 641c727b679cbd76802ed3b57064e993 290 Gene3D G3DSA:3.40.190.10 134 236 1.0E-77 T 11-10-2018 UP12_15610 2744e226eb6b8e0df84cb578d0e379dc 478 SUPERFAMILY SSF51556 2 464 1.36E-179 T 11-10-2018 IPR032466 Metal-dependent hydrolase UP12_15610 2744e226eb6b8e0df84cb578d0e379dc 478 Gene3D G3DSA:3.20.20.140 7 463 1.4E-196 T 11-10-2018 UP12_15610 2744e226eb6b8e0df84cb578d0e379dc 478 Gene3D G3DSA:1.10.2020.10 46 136 1.4E-196 T 11-10-2018 UP12_15610 2744e226eb6b8e0df84cb578d0e379dc 478 Pfam PF02614 Glucuronate isomerase 1 463 2.4E-229 T 11-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 UP12_15610 2744e226eb6b8e0df84cb578d0e379dc 478 Hamap MF_00675 Uronate isomerase [uxaC]. 2 465 50.02 T 11-10-2018 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248 UP12_07460 937c2a1b2c37ff2c8ef33b716c17cc7e 336 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 6 189 7.8E-72 T 11-10-2018 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198 UP12_07460 937c2a1b2c37ff2c8ef33b716c17cc7e 336 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 244 336 2.7E-46 T 11-10-2018 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.198 UP12_03235 1950bf0ecca3bafe6c0976a1286fefa4 124 SUPERFAMILY SSF69118 52 120 1.35E-15 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UP12_03235 1950bf0ecca3bafe6c0976a1286fefa4 124 Gene3D G3DSA:1.20.1290.10 9 123 7.7E-17 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 UP12_03235 1950bf0ecca3bafe6c0976a1286fefa4 124 Pfam PF02627 Carboxymuconolactone decarboxylase family 52 115 8.4E-8 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 UP12_11335 916669588cf17fe0679ed2713cbbe488 256 Pfam PF06691 Protein of unknown function (DUF1189) 4 242 9.2E-70 T 11-10-2018 IPR009574 Protein of unknown function DUF1189 UP12_02035 0d02a207dcd41d7f297db51dc89c53a7 445 Pfam PF00155 Aminotransferase class I and II 98 396 1.9E-21 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 UP12_02035 0d02a207dcd41d7f297db51dc89c53a7 445 Gene3D G3DSA:1.10.10.10 2 68 6.1E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_02035 0d02a207dcd41d7f297db51dc89c53a7 445 SUPERFAMILY SSF53383 61 441 2.42E-68 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_02035 0d02a207dcd41d7f297db51dc89c53a7 445 SMART SM00345 7 66 1.9E-17 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02035 0d02a207dcd41d7f297db51dc89c53a7 445 Gene3D G3DSA:3.40.640.10 69 433 7.8E-89 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_02035 0d02a207dcd41d7f297db51dc89c53a7 445 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.4E-15 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 UP12_02035 0d02a207dcd41d7f297db51dc89c53a7 445 SUPERFAMILY SSF46785 2 70 5.29E-17 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_15710 8532f7cb7e556d90ece82ae96dccadc1 228 SUPERFAMILY SSF52833 42 220 4.82E-40 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_15710 8532f7cb7e556d90ece82ae96dccadc1 228 Pfam PF13462 Thioredoxin 49 221 2.2E-39 T 11-10-2018 IPR012336 Thioredoxin-like fold UP12_15710 8532f7cb7e556d90ece82ae96dccadc1 228 Gene3D G3DSA:3.40.30.10 31 228 5.7E-60 T 11-10-2018 UP12_17025 010ee4db8805726c5669031964122aef 395 Gene3D G3DSA:1.20.1250.20 4 380 1.9E-52 T 11-10-2018 UP12_17025 010ee4db8805726c5669031964122aef 395 Pfam PF07690 Major Facilitator Superfamily 14 253 1.5E-30 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_17025 010ee4db8805726c5669031964122aef 395 SUPERFAMILY SSF103473 1 387 1.31E-61 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_06240 e3caa384b225ddbf6067a05909721b40 261 SUPERFAMILY SSF51735 10 249 7.11E-69 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_06240 e3caa384b225ddbf6067a05909721b40 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 4.3E-54 T 11-10-2018 UP12_06240 e3caa384b225ddbf6067a05909721b40 261 Gene3D G3DSA:3.40.50.720 7 259 5.6E-67 T 11-10-2018 UP12_06240 e3caa384b225ddbf6067a05909721b40 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06240 e3caa384b225ddbf6067a05909721b40 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06240 e3caa384b225ddbf6067a05909721b40 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.1E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06240 e3caa384b225ddbf6067a05909721b40 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06240 e3caa384b225ddbf6067a05909721b40 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_06240 e3caa384b225ddbf6067a05909721b40 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-31 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_12805 539c1c62d71a23cdb3190d804f83be10 239 Pfam PF03099 Biotin/lipoate A/B protein ligase family 9 127 4.7E-13 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 UP12_12805 539c1c62d71a23cdb3190d804f83be10 239 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 3 233 5.3E-41 T 11-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 UP12_12805 539c1c62d71a23cdb3190d804f83be10 239 SUPERFAMILY SSF55681 2 184 7.81E-44 T 11-10-2018 UP12_12805 539c1c62d71a23cdb3190d804f83be10 239 Gene3D G3DSA:3.30.930.10 2 185 7.5E-46 T 11-10-2018 UP12_00985 b8cf58a7fa44e3cfc9e82fb8b5845933 479 ProSitePatterns PS01130 SLC26A transporters signature. 43 64 - T 11-10-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 UP12_00985 b8cf58a7fa44e3cfc9e82fb8b5845933 479 SUPERFAMILY SSF52091 392 475 5.1E-14 T 11-10-2018 IPR036513 STAS domain superfamily UP12_00985 b8cf58a7fa44e3cfc9e82fb8b5845933 479 Pfam PF01740 STAS domain 392 476 1.1E-12 T 11-10-2018 IPR002645 STAS domain UP12_00985 b8cf58a7fa44e3cfc9e82fb8b5845933 479 Gene3D G3DSA:3.30.750.24 385 477 3.8E-26 T 11-10-2018 IPR036513 STAS domain superfamily UP12_00985 b8cf58a7fa44e3cfc9e82fb8b5845933 479 Pfam PF00916 Sulfate permease family 15 143 4.5E-28 T 11-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UP12_00985 b8cf58a7fa44e3cfc9e82fb8b5845933 479 Pfam PF00916 Sulfate permease family 164 355 1.2E-33 T 11-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 UP12_10715 bafcf4c1fab2e6c459de01c2a9fa5026 316 Pfam PF00753 Metallo-beta-lactamase superfamily 19 230 5.3E-17 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_10715 bafcf4c1fab2e6c459de01c2a9fa5026 316 Gene3D G3DSA:3.60.15.10 1 258 1.7E-48 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_10715 bafcf4c1fab2e6c459de01c2a9fa5026 316 SUPERFAMILY SSF56281 2 302 5.11E-42 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_10715 bafcf4c1fab2e6c459de01c2a9fa5026 316 SMART SM00849 18 230 5.1E-18 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_10190 72975c55c7b6228aaddc0370a2464212 363 Pfam PF01761 3-dehydroquinate synthase 68 323 1.0E-96 T 11-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UP12_10190 72975c55c7b6228aaddc0370a2464212 363 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 359 68.572 T 11-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UP12_10190 72975c55c7b6228aaddc0370a2464212 363 PIRSF PIRSF001455 3 362 9.0E-105 T 11-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UP12_10190 72975c55c7b6228aaddc0370a2464212 363 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 351 3.9E-117 T 11-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 UP12_10190 72975c55c7b6228aaddc0370a2464212 363 SUPERFAMILY SSF56796 7 357 1.15E-97 T 11-10-2018 UP12_10190 72975c55c7b6228aaddc0370a2464212 363 Gene3D G3DSA:1.20.1090.10 173 360 1.1E-51 T 11-10-2018 UP12_10190 72975c55c7b6228aaddc0370a2464212 363 Gene3D G3DSA:3.40.50.1970 1 172 3.8E-63 T 11-10-2018 UP12_16895 ba7d1edf6b6bbd49dcc851cee611f85a 130 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 130 31.128 T 11-10-2018 IPR023064 D-ribose pyranase GO:0016872 UP12_16895 ba7d1edf6b6bbd49dcc851cee611f85a 130 Gene3D G3DSA:3.40.1650.10 8 126 1.9E-35 T 11-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UP12_16895 ba7d1edf6b6bbd49dcc851cee611f85a 130 Pfam PF05025 RbsD / FucU transport protein family 1 129 1.1E-45 T 11-10-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UP12_16895 ba7d1edf6b6bbd49dcc851cee611f85a 130 SUPERFAMILY SSF102546 1 130 2.35E-42 T 11-10-2018 IPR023750 RbsD-like superfamily GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 UP12_04145 d3bd1eac55d5223e824ac7377eab0f9e 502 Pfam PF05043 Mga helix-turn-helix domain 78 159 3.7E-17 T 11-10-2018 IPR007737 Mga helix-turn-helix domain UP12_04145 d3bd1eac55d5223e824ac7377eab0f9e 502 Gene3D G3DSA:1.10.10.10 1 147 1.0E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_11200 d5f9ff4b832752800392f42799904eb6 290 SUPERFAMILY SSF52091 169 275 1.28E-16 T 11-10-2018 IPR036513 STAS domain superfamily UP12_11200 d5f9ff4b832752800392f42799904eb6 290 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 12 109 3.1E-5 T 11-10-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain UP12_11200 d5f9ff4b832752800392f42799904eb6 290 Pfam PF01740 STAS domain 170 268 4.0E-13 T 11-10-2018 IPR002645 STAS domain UP12_11200 d5f9ff4b832752800392f42799904eb6 290 Gene3D G3DSA:3.30.750.24 164 279 7.3E-35 T 11-10-2018 IPR036513 STAS domain superfamily UP12_03200 7c5dac227243ac9f787a592d77dd64a6 172 Gene3D G3DSA:3.40.630.30 1 172 4.8E-44 T 11-10-2018 UP12_03200 7c5dac227243ac9f787a592d77dd64a6 172 SUPERFAMILY SSF55729 3 171 1.06E-29 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_03200 7c5dac227243ac9f787a592d77dd64a6 172 Pfam PF00583 Acetyltransferase (GNAT) family 48 147 7.5E-18 T 11-10-2018 IPR000182 GNAT domain UP12_14235 4abc8745b6d97a60269fca0fd7dbe722 168 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 7 92 9.3E-8 T 11-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component UP12_14235 4abc8745b6d97a60269fca0fd7dbe722 168 ProDom PD034535 XKDI PHAGE PHAGE-LIKE PBSX LIN1275 RELATED ELEMENT YQBI 1 162 3.0E-69 T 11-10-2018 UP12_01185 aedd5b5efcdd8974df8abbfbaf3aa6e2 201 Pfam PF13346 ABC-2 family transporter protein 3 197 9.8E-35 T 11-10-2018 IPR025699 ABC-2 membrane transporter-like UP12_04975 760bde89da8e232f97b3b7225509b882 69 ProDom PD056348 YHEE BH1143 1 69 3.0E-27 T 11-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 UP12_04975 760bde89da8e232f97b3b7225509b882 69 Pfam PF17277 Family of unknown function (DUF5342) 1 69 4.5E-34 T 11-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 UP12_04975 760bde89da8e232f97b3b7225509b882 69 PIRSF PIRSF037692 1 69 1.1E-35 T 11-10-2018 IPR017263 Uncharacterised conserved protein UCP037692 UP12_18220 373d3d2311f3e60fabf720b078b61665 175 Pfam PF17353 Family of unknown function (DUF5381) 5 172 5.1E-69 T 11-10-2018 IPR035324 Protein of unknown function DUF5381 UP12_18220 373d3d2311f3e60fabf720b078b61665 175 ProDom PD033957 LIPOPROTEIN MEMBRANE TRANSMEMBRANE YFJD PALMITATE YFJE PRECURSOR SIGNAL 38 173 4.0E-22 T 11-10-2018 IPR035324 Protein of unknown function DUF5381 UP12_19070 b60e44d690bcc8ea1f46bb9d0b702511 202 Pfam PF01738 Dienelactone hydrolase family 89 186 4.1E-7 T 11-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 UP12_19070 b60e44d690bcc8ea1f46bb9d0b702511 202 Gene3D G3DSA:3.40.50.1820 1 201 1.4E-48 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_19070 b60e44d690bcc8ea1f46bb9d0b702511 202 SUPERFAMILY SSF53474 2 201 1.98E-55 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 Gene3D G3DSA:1.20.1250.20 208 395 1.4E-31 T 11-10-2018 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 SUPERFAMILY SSF103473 2 391 1.57E-67 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 Pfam PF00083 Sugar (and other) transporter 246 381 1.1E-6 T 11-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 Gene3D G3DSA:1.20.1250.20 1 193 2.7E-30 T 11-10-2018 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 Pfam PF07690 Major Facilitator Superfamily 5 237 1.7E-25 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 PRINTS PR01035 Tetracycline resistance protein signature 130 152 5.1E-7 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 PRINTS PR01035 Tetracycline resistance protein signature 73 97 5.1E-7 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 PRINTS PR01035 Tetracycline resistance protein signature 335 358 5.1E-7 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 PRINTS PR01035 Tetracycline resistance protein signature 42 61 5.1E-7 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_14860 ad390fa2d3f5ca56953622a88f425be5 395 PRINTS PR01035 Tetracycline resistance protein signature 100 121 5.1E-7 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 UP12_01870 946fe4e29480dbee95e5932533a6a3e9 257 SUPERFAMILY SSF53335 8 210 3.59E-41 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_01870 946fe4e29480dbee95e5932533a6a3e9 257 Gene3D G3DSA:3.40.50.150 24 257 8.5E-66 T 11-10-2018 UP12_01870 946fe4e29480dbee95e5932533a6a3e9 257 Pfam PF13847 Methyltransferase domain 42 159 5.7E-25 T 11-10-2018 IPR025714 Methyltransferase domain UP12_00940 bcd9f0f6390da5b7030626e42b8f9335 352 SUPERFAMILY SSF52540 108 348 1.78E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_00940 bcd9f0f6390da5b7030626e42b8f9335 352 Hamap MF_02040 Iron-sulfur cluster carrier protein. 97 345 33.576 T 11-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein UP12_00940 bcd9f0f6390da5b7030626e42b8f9335 352 ProSitePatterns PS01215 Mrp family signature. 210 226 - T 11-10-2018 IPR000808 Mrp, conserved site GO:0005524 UP12_00940 bcd9f0f6390da5b7030626e42b8f9335 352 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 108 344 4.2E-86 T 11-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 UP12_00940 bcd9f0f6390da5b7030626e42b8f9335 352 Gene3D G3DSA:3.40.50.300 99 321 7.8E-68 T 11-10-2018 UP12_12750 b6112ec54bfbb7034e746b7c8d29fdd8 69 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 15 62 4.0E-11 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA UP12_12750 b6112ec54bfbb7034e746b7c8d29fdd8 69 Pfam PF17356 Phage-like element PBSX protein XtrA 3 66 5.1E-17 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA UP12_13480 d71a4c45e330530316c77131379161c1 104 Pfam PF03413 Peptidase propeptide and YPEB domain 29 98 2.8E-5 T 11-10-2018 IPR025711 PepSY domain UP12_05410 c10e61016834860359a794407687996f 491 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 6 485 2.4E-116 T 11-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 UP12_05410 c10e61016834860359a794407687996f 491 Gene3D G3DSA:3.50.50.60 1 111 5.7E-15 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05410 c10e61016834860359a794407687996f 491 Gene3D G3DSA:3.50.50.60 197 328 1.0E-10 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05410 c10e61016834860359a794407687996f 491 Pfam PF01593 Flavin containing amine oxidoreductase 12 471 1.4E-27 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 UP12_05410 c10e61016834860359a794407687996f 491 SUPERFAMILY SSF51905 1 481 3.24E-62 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05605 b3b98995edd12673427b2840f6e98b74 421 Pfam PF07690 Major Facilitator Superfamily 37 362 3.5E-23 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_05605 b3b98995edd12673427b2840f6e98b74 421 SUPERFAMILY SSF103473 12 405 4.05E-36 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_05605 b3b98995edd12673427b2840f6e98b74 421 Gene3D G3DSA:1.20.1250.20 10 401 6.9E-29 T 11-10-2018 UP12_14670 eb4de35bd1d7f060ad776dc1c61aa5cc 87 SMART SM00530 5 61 1.5E-8 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_14670 eb4de35bd1d7f060ad776dc1c61aa5cc 87 Gene3D G3DSA:1.10.260.40 3 85 3.7E-12 T 11-10-2018 UP12_14670 eb4de35bd1d7f060ad776dc1c61aa5cc 87 Pfam PF01381 Helix-turn-helix 6 61 9.3E-10 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 UP12_14670 eb4de35bd1d7f060ad776dc1c61aa5cc 87 SUPERFAMILY SSF47413 4 66 1.57E-10 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 UP12_16815 a29d44e0aa703d6fd27a4219bc598397 488 PIRSF PIRSF005690 1 488 7.7E-175 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_16815 a29d44e0aa703d6fd27a4219bc598397 488 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 15 476 1.2E-173 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_05470 5d2ef45f08491819800b10eb6e36d39b 449 SUPERFAMILY SSF51905 7 255 1.85E-16 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05470 5d2ef45f08491819800b10eb6e36d39b 449 Gene3D G3DSA:3.50.50.60 1 431 1.1E-128 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily UP12_05470 5d2ef45f08491819800b10eb6e36d39b 449 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 10 347 4.1E-122 T 11-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase UP12_08430 e426963a9bc02d52512580f10aece753 133 Pfam PF12788 YmaF family 14 69 2.5E-9 T 11-10-2018 IPR024307 YmaF UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 SUPERFAMILY SSF52768 4 372 2.59E-104 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01270 Histone deacetylase superfamily signature 162 177 2.3E-17 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01270 Histone deacetylase superfamily signature 129 152 2.3E-17 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01270 Histone deacetylase superfamily signature 248 258 2.3E-17 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 Pfam PF00850 Histone deacetylase domain 21 315 5.2E-75 T 11-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 Gene3D G3DSA:3.40.800.20 1 372 3.9E-100 T 11-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 312 331 4.0E-52 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 4.0E-52 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 273 289 4.0E-52 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 349 368 4.0E-52 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 106 119 4.0E-52 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 332 348 4.0E-52 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UP12_13410 5c89770ae550be1998e57fbae2df81b1 386 PRINTS PR01272 Acetoin utilisation ACUC protein signature 85 99 4.0E-52 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 UP12_10370 4aa86c802cd337463b0f6a02221cee8b 180 PIRSF PIRSF037778 1 176 4.4E-41 T 11-10-2018 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 UP12_10370 4aa86c802cd337463b0f6a02221cee8b 180 Gene3D G3DSA:1.10.1760.20 1 179 3.2E-46 T 11-10-2018 UP12_10370 4aa86c802cd337463b0f6a02221cee8b 180 Pfam PF12822 ECF transporter, substrate-specific component 1 162 2.9E-21 T 11-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 UP12_11780 36dc86111050548e8d7117e0b5f4433c 210 SMART SM00934 2 203 1.8E-36 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_11780 36dc86111050548e8d7117e0b5f4433c 210 Gene3D G3DSA:3.20.20.70 1 210 6.3E-71 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_11780 36dc86111050548e8d7117e0b5f4433c 210 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 2 207 1.6E-82 T 11-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 UP12_11780 36dc86111050548e8d7117e0b5f4433c 210 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 202 1.4E-26 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 UP12_11780 36dc86111050548e8d7117e0b5f4433c 210 SUPERFAMILY SSF51366 2 207 6.38E-37 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_05075 9cd4b3facd5e92bdd8c950be87a8a5d6 172 Pfam PF11667 Putative zincin peptidase 59 153 3.3E-16 T 11-10-2018 IPR021683 Putative zincin peptidase UP12_07130 bdbfe41e6dc48ba3edd7f6e6f225afa8 98 Gene3D G3DSA:1.10.10.1320 2 62 1.3E-5 T 11-10-2018 UP12_07130 bdbfe41e6dc48ba3edd7f6e6f225afa8 98 Pfam PF13490 Putative zinc-finger 3 37 9.2E-8 T 11-10-2018 IPR027383 Putative zinc-finger UP12_07735 bcc4a99fd963c9c965d7a625510f49d8 188 Gene3D G3DSA:1.10.10.10 1 60 4.3E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_07735 bcc4a99fd963c9c965d7a625510f49d8 188 Hamap MF_01814 Transcription factor FapR [fapR]. 1 188 39.345 T 11-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 UP12_07735 bcc4a99fd963c9c965d7a625510f49d8 188 PIRSF PIRSF037733 1 188 5.5E-85 T 11-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 UP12_07735 bcc4a99fd963c9c965d7a625510f49d8 188 SUPERFAMILY SSF54637 74 183 5.23E-24 T 11-10-2018 IPR029069 HotDog domain superfamily UP12_07735 bcc4a99fd963c9c965d7a625510f49d8 188 Gene3D G3DSA:3.10.129.10 68 188 1.1E-39 T 11-10-2018 UP12_11020 e524ea49b36d06754c7af9faeec61ab2 210 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 111 5.0E-36 T 11-10-2018 IPR014245 Sporulation stage III, protein AF UP12_11020 e524ea49b36d06754c7af9faeec61ab2 210 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 198 6.3E-38 T 11-10-2018 IPR014245 Sporulation stage III, protein AF UP12_02385 90126c33934a294824a30b1e8e2152f3 608 Gene3D G3DSA:1.20.1740.10 41 466 1.1E-23 T 11-10-2018 UP12_02385 90126c33934a294824a30b1e8e2152f3 608 Pfam PF13520 Amino acid permease 27 446 1.5E-35 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_03325 732825648406429aede9179004d34257 173 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 107 159 1.2E-6 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 UP12_03325 732825648406429aede9179004d34257 173 Hamap MF_01515 UPF0316 protein . 1 167 28.926 T 11-10-2018 IPR022930 Protein of unknown function UPF0316 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 Gene3D G3DSA:2.40.50.140 1 66 1.4E-30 T 11-10-2018 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 6.0E-30 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 11-10-2018 IPR019844 Cold-shock conserved site UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 PRINTS PR00050 Cold shock protein signature 39 57 7.2E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 PRINTS PR00050 Cold shock protein signature 24 33 7.2E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 PRINTS PR00050 Cold shock protein signature 4 19 7.2E-19 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 PIRSF PIRSF002599 1 66 6.0E-24 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 SMART SM00357 3 66 2.4E-30 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 UP12_04695 18c8c5fb2ca5ce1ea8304b181ecd3f05 66 SUPERFAMILY SSF50249 1 64 2.29E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_15475 05088e234e7f37dca37f211764675b9e 83 ProDom PD065427 YUSU IG COIL COILED BH3491 16 79 6.0E-24 T 11-10-2018 IPR020393 Uncharacterised protein family YusU UP12_15475 05088e234e7f37dca37f211764675b9e 83 Pfam PF10835 Protein of unknown function (DUF2573) 4 79 1.5E-40 T 11-10-2018 IPR020393 Uncharacterised protein family YusU UP12_10250 f8b44bc008e81561dce51302f5b10e3b 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 9.1E-26 T 11-10-2018 IPR020076 Protein of unknown function DUF2768 UP12_10250 f8b44bc008e81561dce51302f5b10e3b 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 2.0E-22 T 11-10-2018 IPR020076 Protein of unknown function DUF2768 UP12_18340 355d11308c352a319721b3358d8bf915 84 Pfam PF10552 ORF6C domain 35 70 3.0E-5 T 11-10-2018 IPR018878 ORF6C domain UP12_13335 dc4721f893bcf8e5b7d135ebc3fb0130 447 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 14 420 6.0E-157 T 11-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 UP12_13335 dc4721f893bcf8e5b7d135ebc3fb0130 447 Pfam PF05525 Branched-chain amino acid transport protein 7 432 7.7E-162 T 11-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 UP12_09385 835e8b6aa095b92d03791a6b4cdb80e8 110 SUPERFAMILY SSF50249 2 109 1.27E-28 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold UP12_09385 835e8b6aa095b92d03791a6b4cdb80e8 110 Gene3D G3DSA:2.40.50.140 1 110 3.3E-30 T 11-10-2018 UP12_09385 835e8b6aa095b92d03791a6b4cdb80e8 110 Pfam PF01588 Putative tRNA binding domain 12 108 2.0E-16 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 UP12_09385 835e8b6aa095b92d03791a6b4cdb80e8 110 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 5 109 9.3E-47 T 11-10-2018 IPR008231 Probable chaperone CsaA UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 Gene3D G3DSA:3.40.710.10 286 493 1.3E-56 T 11-10-2018 UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 67 471 6.6E-125 T 11-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 449 462 1.7E-27 T 11-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 79 98 1.7E-27 T 11-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 367 381 1.7E-27 T 11-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 310 332 1.7E-27 T 11-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 SUPERFAMILY SSF56601 49 492 9.67E-99 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 41 492 3.5E-134 T 11-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 UP12_09265 eb735cf56805e1ed937e5c2cf4989e97 494 Gene3D G3DSA:3.50.80.20 103 194 2.6E-21 T 11-10-2018 UP12_09710 d4cbdb33914ddd1fc1dc3f05903881b0 178 Gene3D G3DSA:3.30.1060.10 1 165 2.0E-67 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UP12_09710 d4cbdb33914ddd1fc1dc3f05903881b0 178 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 164 36.809 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UP12_09710 d4cbdb33914ddd1fc1dc3f05903881b0 178 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 6 157 2.1E-66 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UP12_09710 d4cbdb33914ddd1fc1dc3f05903881b0 178 Pfam PF01625 Peptide methionine sulfoxide reductase 8 158 5.6E-62 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UP12_09710 d4cbdb33914ddd1fc1dc3f05903881b0 178 SUPERFAMILY SSF55068 3 168 7.19E-73 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 UP12_18030 1cb570fd61ef4a5322ad35c845da2a7b 103 Pfam PF17280 Family of unknown function (DUF5345) 10 85 2.1E-22 T 11-10-2018 IPR035238 Protein of unknown function DUF5345 UP12_18030 1cb570fd61ef4a5322ad35c845da2a7b 103 ProDom PD070249 YXLC MEMBRANE TRANSMEMBRANE 10 83 4.0E-5 T 11-10-2018 IPR035238 Protein of unknown function DUF5345 UP12_15425 4b17ec336e1754adca09abc11fadb0b4 100 SUPERFAMILY SSF52833 9 97 7.68E-16 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_15425 4b17ec336e1754adca09abc11fadb0b4 100 Pfam PF00085 Thioredoxin 5 82 1.1E-9 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 UP12_15425 4b17ec336e1754adca09abc11fadb0b4 100 Gene3D G3DSA:3.40.30.10 2 99 1.2E-13 T 11-10-2018 UP12_17685 d1c960a8e05b99ec7912b0df2852b645 256 SUPERFAMILY SSF53448 3 227 6.66E-40 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_17685 d1c960a8e05b99ec7912b0df2852b645 256 Pfam PF00535 Glycosyl transferase family 2 5 167 1.2E-23 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_17685 d1c960a8e05b99ec7912b0df2852b645 256 Gene3D G3DSA:3.90.550.10 3 255 2.4E-82 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_15485 b5d623a4cf5c74e633120c32dee1e689 149 Pfam PF14039 YusW-like protein 49 139 4.4E-24 T 11-10-2018 IPR025623 YusW-like protein UP12_08400 1e44c5b9e81123b2f3e7167a9bf8e3b0 244 Gene3D G3DSA:3.40.630.100 39 244 3.4E-57 T 11-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily UP12_08400 1e44c5b9e81123b2f3e7167a9bf8e3b0 244 Pfam PF05908 Poly-gamma-glutamate hydrolase 44 234 5.5E-69 T 11-10-2018 IPR008585 Poly-gamma-glutamate hydrolase UP12_15105 da3cea48f0cc46e7784e33b228db2b7c 158 Pfam PF02681 Divergent PAP2 family 5 148 2.4E-50 T 11-10-2018 IPR003832 Protein of unknown function DUF212 UP12_17885 e62fded5247f2890466a26d6440872ff 124 Pfam PF12680 SnoaL-like domain 18 109 6.5E-8 T 11-10-2018 IPR037401 SnoaL-like domain UP12_17885 e62fded5247f2890466a26d6440872ff 124 Gene3D G3DSA:3.10.450.50 1 124 2.0E-41 T 11-10-2018 UP12_17885 e62fded5247f2890466a26d6440872ff 124 SUPERFAMILY SSF54427 3 112 4.27E-21 T 11-10-2018 IPR032710 NTF2-like domain superfamily UP12_13930 f336d55590d33e058bc9b63e593cc4a8 158 Pfam PF03073 TspO/MBR family 13 154 1.3E-27 T 11-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 UP12_13930 f336d55590d33e058bc9b63e593cc4a8 158 PIRSF PIRSF005859 1 158 6.1E-37 T 11-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 UP12_13930 f336d55590d33e058bc9b63e593cc4a8 158 Gene3D G3DSA:1.20.1260.100 3 158 1.9E-28 T 11-10-2018 IPR038330 TspO/MBR-related superfamily UP12_01695 9a2f1deb8fc5a40e686f64a9b38b5863 274 SUPERFAMILY SSF53474 21 262 5.05E-34 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_01695 9a2f1deb8fc5a40e686f64a9b38b5863 274 Gene3D G3DSA:3.40.50.1820 23 262 1.0E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_01695 9a2f1deb8fc5a40e686f64a9b38b5863 274 Pfam PF12697 Alpha/beta hydrolase family 31 180 2.7E-14 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_16840 dde579aefb3514d1be2c4811d09583e5 321 Gene3D G3DSA:1.10.260.150 59 321 6.5E-82 T 11-10-2018 UP12_16840 dde579aefb3514d1be2c4811d09583e5 321 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 93 241 6.1E-41 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_16840 dde579aefb3514d1be2c4811d09583e5 321 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 92 241 3.9E-35 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain UP12_09610 133b3fcbad23e6b2f3d4a81f2926cc2a 497 Pfam PF00474 Sodium:solute symporter family 40 432 1.5E-23 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 UP12_09610 133b3fcbad23e6b2f3d4a81f2926cc2a 497 Gene3D G3DSA:1.20.1730.10 27 495 1.2E-41 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily UP12_03565 a9c979aeeed1632b207e4b77e762f67d 230 Pfam PF02308 MgtC family 13 141 1.4E-32 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 UP12_03565 a9c979aeeed1632b207e4b77e762f67d 230 PRINTS PR01837 MgtC/SapB protein signature 16 35 7.2E-41 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 UP12_03565 a9c979aeeed1632b207e4b77e762f67d 230 PRINTS PR01837 MgtC/SapB protein signature 97 121 7.2E-41 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 UP12_03565 a9c979aeeed1632b207e4b77e762f67d 230 PRINTS PR01837 MgtC/SapB protein signature 35 53 7.2E-41 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 UP12_03565 a9c979aeeed1632b207e4b77e762f67d 230 PRINTS PR01837 MgtC/SapB protein signature 69 91 7.2E-41 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 UP12_03780 35f2c9e44e3521ad39b0683a399791b7 463 Pfam PF13520 Amino acid permease 26 429 1.2E-60 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_03780 35f2c9e44e3521ad39b0683a399791b7 463 Gene3D G3DSA:1.20.1740.10 20 462 1.1E-132 T 11-10-2018 UP12_03780 35f2c9e44e3521ad39b0683a399791b7 463 PIRSF PIRSF006060 11 462 4.0E-89 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_13835 e50d5f88f974eef3574bc03644997c39 144 Pfam PF13115 YtkA-like 31 111 2.4E-18 T 11-10-2018 IPR032693 YtkA-like domain UP12_19590 1bc9afde9e6b7b31560f5792723c3f57 255 Pfam PF13034 Protein of unknown function (DUF3895) 204 250 3.4E-7 T 11-10-2018 IPR024995 Protein of unknown function DUF3895 UP12_05015 5c0f61799c5d062ed8e9b551848d0545 407 Pfam PF00999 Sodium/hydrogen exchanger family 12 377 3.5E-58 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 UP12_05015 5c0f61799c5d062ed8e9b551848d0545 407 Gene3D G3DSA:1.20.1530.20 2 386 9.7E-61 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily UP12_06655 07ba492d02e92258f4f6cf54c2bc0875 62 Pfam PF09953 Uncharacterized protein conserved in bacteria (DUF2187) 2 57 5.3E-28 T 11-10-2018 IPR018690 Protein of unknown function DUF2187 UP12_08595 b0de9fdcf81d864923d899392bff50e8 156 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 126 1.2E-4 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_08595 b0de9fdcf81d864923d899392bff50e8 156 Gene3D G3DSA:3.10.180.10 5 148 2.5E-25 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_08595 b0de9fdcf81d864923d899392bff50e8 156 SUPERFAMILY SSF54593 1 144 6.19E-21 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_17575 7db43e8d6cae6363d2678135e2365ef2 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 75 6.5E-15 T 11-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 UP12_17575 7db43e8d6cae6363d2678135e2365ef2 283 Pfam PF01380 SIS domain 128 229 5.2E-12 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 UP12_17575 7db43e8d6cae6363d2678135e2365ef2 283 Gene3D G3DSA:3.40.50.10490 94 278 2.5E-32 T 11-10-2018 UP12_17575 7db43e8d6cae6363d2678135e2365ef2 283 Gene3D G3DSA:1.10.10.10 1 77 8.2E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_17575 7db43e8d6cae6363d2678135e2365ef2 283 SUPERFAMILY SSF46689 2 77 1.43E-18 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_17575 7db43e8d6cae6363d2678135e2365ef2 283 SUPERFAMILY SSF53697 96 276 4.0E-20 T 11-10-2018 UP12_15065 56533627e6e5a94f8104d864913c65d2 79 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 3 78 7.9E-12 T 11-10-2018 IPR024962 YukD-like UP12_15065 56533627e6e5a94f8104d864913c65d2 79 Gene3D G3DSA:3.10.20.90 1 79 6.3E-39 T 11-10-2018 UP12_08910 76b4d42050e15cbe54d5872d816758bb 115 Pfam PF13564 DoxX-like family 8 108 5.6E-13 T 11-10-2018 IPR032808 DoxX family UP12_06530 a7c18f6532d7b3a6d99361cf2b229879 172 Pfam PF04239 Protein of unknown function (DUF421) 83 153 1.4E-19 T 11-10-2018 IPR007353 Protein of unknown function DUF421 UP12_06530 a7c18f6532d7b3a6d99361cf2b229879 172 Gene3D G3DSA:3.30.240.20 76 149 1.1E-16 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily UP12_03130 23612e48a2fc117647024a3e72ccdaca 229 SUPERFAMILY SSF53067 108 214 1.06E-13 T 11-10-2018 UP12_03130 23612e48a2fc117647024a3e72ccdaca 229 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 4.2E-52 T 11-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 UP12_03130 23612e48a2fc117647024a3e72ccdaca 229 Pfam PF00814 Glycoprotease family 32 198 4.5E-30 T 11-10-2018 IPR000905 Gcp-like domain UP12_03130 23612e48a2fc117647024a3e72ccdaca 229 Gene3D G3DSA:3.30.420.40 95 189 1.2E-47 T 11-10-2018 UP12_03130 23612e48a2fc117647024a3e72ccdaca 229 SUPERFAMILY SSF53067 3 107 6.91E-27 T 11-10-2018 UP12_03130 23612e48a2fc117647024a3e72ccdaca 229 Gene3D G3DSA:3.30.420.40 3 216 1.2E-47 T 11-10-2018 UP12_04830 b2c3393cc8d90195eb7ea8152af4906f 127 Gene3D G3DSA:3.10.450.390 44 126 1.6E-10 T 11-10-2018 UP12_04830 b2c3393cc8d90195eb7ea8152af4906f 127 Pfam PF13028 Protein of unknown function (DUF3889) 41 126 2.2E-29 T 11-10-2018 IPR024987 Protein of unknown function DUF3889 UP12_01885 995e68010fec26791b0c2b7dd74b0b13 319 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 314 2.2E-140 T 11-10-2018 IPR008391 Acetyl xylan esterase UP12_01885 995e68010fec26791b0c2b7dd74b0b13 319 Gene3D G3DSA:3.40.50.1820 1 317 7.4E-103 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_01885 995e68010fec26791b0c2b7dd74b0b13 319 SUPERFAMILY SSF53474 7 316 1.71E-42 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02310 97780c6e66794de3b6cfee483b16c930 140 Gene3D G3DSA:2.30.110.10 3 137 2.9E-44 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 UP12_02310 97780c6e66794de3b6cfee483b16c930 140 SUPERFAMILY SSF50475 4 132 7.11E-34 T 11-10-2018 UP12_02310 97780c6e66794de3b6cfee483b16c930 140 Pfam PF16242 Pyridoxamine 5'-phosphate oxidase like 7 129 3.0E-21 T 11-10-2018 IPR038725 General stress protein, FMN-binding split barrel domain UP12_02435 2ed8c48beff0a2db029cb6691ed202c1 365 Gene3D G3DSA:3.40.190.170 44 347 1.4E-89 T 11-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily UP12_02435 2ed8c48beff0a2db029cb6691ed202c1 365 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 49 304 5.3E-92 T 11-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 UP12_02435 2ed8c48beff0a2db029cb6691ed202c1 365 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 49 333 9.8E-95 T 11-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 UP12_02435 2ed8c48beff0a2db029cb6691ed202c1 365 PIRSF PIRSF006470 16 349 2.5E-123 T 11-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 UP12_00595 a6c55c7b3608d21e33e3e02448d1e81d 366 SUPERFAMILY SSF88723 166 294 6.87E-23 T 11-10-2018 IPR029060 PIN-like domain superfamily UP12_00595 a6c55c7b3608d21e33e3e02448d1e81d 366 Gene3D G3DSA:3.40.50.1010 162 297 4.8E-52 T 11-10-2018 UP12_00595 a6c55c7b3608d21e33e3e02448d1e81d 366 SMART SM00670 166 273 1.9E-14 T 11-10-2018 IPR002716 PIN domain UP12_07225 e40fe2f61285ad845e9e9debd8cd42a8 109 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 3 109 8.3E-54 T 11-10-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 UP12_07225 e40fe2f61285ad845e9e9debd8cd42a8 109 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 29 100 3.3E-15 T 11-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 UP12_14945 5204d9e0480e085315c5f011791870b9 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 82 4.2E-19 T 11-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 UP12_14945 5204d9e0480e085315c5f011791870b9 93 PIRSF PIRSF028784 1 91 9.4E-34 T 11-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 UP12_09200 1e1565fa5b49dc4231214b7f04d77e8b 495 PIRSF PIRSF005690 3 484 7.6E-141 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_09200 1e1565fa5b49dc4231214b7f04d77e8b 495 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 18 469 3.1E-151 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_15530 c6d76bfba9103888ccef92e467f9722d 373 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 200 365 1.5E-25 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_15530 c6d76bfba9103888ccef92e467f9722d 373 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 367 6.1E-82 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 UP12_15530 c6d76bfba9103888ccef92e467f9722d 373 Gene3D G3DSA:3.30.300.210 218 368 2.2E-33 T 11-10-2018 IPR038501 Spore germination GerAC superfamily UP12_16355 94f85345e17a4e85b2a97c3f3507587a 64 Pfam PF04024 PspC domain 2 61 4.1E-18 T 11-10-2018 IPR007168 Phage shock protein, PspC, N-terminal UP12_15310 2a535ed5dd07c001ddec3a24a57b641a 289 Pfam PF12146 Serine aminopeptidase, S33 33 260 1.8E-28 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 UP12_15310 2a535ed5dd07c001ddec3a24a57b641a 289 Gene3D G3DSA:3.40.50.1820 4 288 3.3E-33 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_15310 2a535ed5dd07c001ddec3a24a57b641a 289 SUPERFAMILY SSF53474 7 268 5.63E-27 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_11910 ae8116e7d4c145d1ef97bde28ffd0933 221 Pfam PF07423 Protein of unknown function (DUF1510) 5 220 8.5E-80 T 11-10-2018 IPR009988 Protein of unknown function DUF1510 UP12_16780 a90a4ebf1536e68eaf7fd135925f7059 333 Pfam PF13407 Periplasmic binding protein domain 48 303 1.3E-48 T 11-10-2018 IPR025997 Periplasmic binding protein UP12_16780 a90a4ebf1536e68eaf7fd135925f7059 333 SUPERFAMILY SSF53822 47 319 1.94E-56 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_16780 a90a4ebf1536e68eaf7fd135925f7059 333 Gene3D G3DSA:3.40.50.2300 52 311 3.5E-64 T 11-10-2018 UP12_16780 a90a4ebf1536e68eaf7fd135925f7059 333 Gene3D G3DSA:3.40.50.2300 149 319 3.5E-64 T 11-10-2018 UP12_03125 90f05fcc6d93744eea687ca4e8d581a1 155 SUPERFAMILY SSF52540 22 120 3.6E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_03125 90f05fcc6d93744eea687ca4e8d581a1 155 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 9 135 5.0E-44 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 UP12_03125 90f05fcc6d93744eea687ca4e8d581a1 155 Gene3D G3DSA:3.40.50.300 2 149 9.2E-41 T 11-10-2018 UP12_03125 90f05fcc6d93744eea687ca4e8d581a1 155 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 7 125 7.0E-38 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 UP12_10130 f31c95bf15be138f458c804b4a352dea 179 SMART SM00914 139 175 3.4E-14 T 11-10-2018 IPR014957 IDEAL domain UP12_10130 f31c95bf15be138f458c804b4a352dea 179 PIRSF PIRSF007165 1 179 9.5E-80 T 11-10-2018 IPR011188 Uncharacterised protein family UPF0302 UP12_10130 f31c95bf15be138f458c804b4a352dea 179 Gene3D G3DSA:1.20.1440.290 1 123 7.5E-55 T 11-10-2018 IPR038091 UPF0302, N-terminal domain superfamily UP12_10130 f31c95bf15be138f458c804b4a352dea 179 Gene3D G3DSA:4.10.810.10 124 179 1.0E-18 T 11-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 UP12_10130 f31c95bf15be138f458c804b4a352dea 179 Pfam PF08864 UPF0302 domain 9 112 9.0E-47 T 11-10-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal UP12_10130 f31c95bf15be138f458c804b4a352dea 179 Hamap MF_00760 UPF0302 protein . 2 178 32.735 T 11-10-2018 IPR011188 Uncharacterised protein family UPF0302 UP12_10130 f31c95bf15be138f458c804b4a352dea 179 Pfam PF08858 IDEAL domain 139 175 5.7E-15 T 11-10-2018 IPR014957 IDEAL domain UP12_14420 6c3be9e152a183c86e6b0e775f1f8ec8 95 Gene3D G3DSA:1.10.8.200 2 68 1.8E-10 T 11-10-2018 UP12_14420 6c3be9e152a183c86e6b0e775f1f8ec8 95 Pfam PF11417 Loader and inhibitor of phage G40P 1 67 2.3E-10 T 11-10-2018 IPR024424 Replicative helicase inhibitor G39P, N-terminal UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.8E-21 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.8E-21 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 5.8E-21 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.8E-21 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.8E-21 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 5.8E-21 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 Pfam PF00106 short chain dehydrogenase 5 192 1.7E-44 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 SUPERFAMILY SSF51735 3 242 6.53E-62 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_15490 c82713b70d485dfdcddb7c3665752d72 281 Gene3D G3DSA:3.40.50.720 2 265 2.5E-66 T 11-10-2018 UP12_12055 1d9a5c735726c623bf6f177e347db4dc 254 Pfam PF00899 ThiF family 6 159 9.6E-36 T 11-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 UP12_12055 1d9a5c735726c623bf6f177e347db4dc 254 Gene3D G3DSA:3.40.50.720 1 254 4.4E-77 T 11-10-2018 UP12_12055 1d9a5c735726c623bf6f177e347db4dc 254 SUPERFAMILY SSF69572 4 244 3.66E-58 T 11-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 UP12_07170 9b744437702773ffe0ca977366f72f44 160 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 3 159 2.0E-42 T 11-10-2018 IPR020229 Uncharacterised protein YlaL UP12_11125 d16ba92424412f1b0139d3e9b507bd04 265 ProDom PD123329 YQHG BH2818 1 261 3.0E-93 T 11-10-2018 IPR024562 Uncharacterised protein family YqhG UP12_11125 d16ba92424412f1b0139d3e9b507bd04 265 Pfam PF11079 Bacterial protein YqhG of unknown function 1 259 9.1E-122 T 11-10-2018 IPR024562 Uncharacterised protein family YqhG UP12_12400 37a087aeba306fa3941b9ef96716879d 199 SUPERFAMILY SSF52016 2 196 2.35E-57 T 11-10-2018 UP12_12400 37a087aeba306fa3941b9ef96716879d 199 Gene3D G3DSA:3.20.19.10 1 174 3.4E-73 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 UP12_12400 37a087aeba306fa3941b9ef96716879d 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 197 41.993 T 11-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 UP12_12400 37a087aeba306fa3941b9ef96716879d 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 186 8.2E-94 T 11-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 UP12_12400 37a087aeba306fa3941b9ef96716879d 199 Pfam PF00694 Aconitase C-terminal domain 1 122 6.7E-34 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 UP12_18275 03767ece72883296733bd45ed9848ab3 374 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 20 348 8.4E-18 T 11-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 UP12_18275 03767ece72883296733bd45ed9848ab3 374 Gene3D G3DSA:3.20.20.210 10 374 2.3E-128 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_18275 03767ece72883296733bd45ed9848ab3 374 SUPERFAMILY SSF51726 18 373 3.14E-84 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 UP12_08165 3eac574e2055aa01cb27a964a3e84f57 317 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 45 312 8.1E-137 T 11-10-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY UP12_08165 3eac574e2055aa01cb27a964a3e84f57 317 Gene3D G3DSA:3.20.20.370 83 316 2.2E-59 T 11-10-2018 UP12_08165 3eac574e2055aa01cb27a964a3e84f57 317 SUPERFAMILY SSF88713 101 311 8.04E-59 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_08165 3eac574e2055aa01cb27a964a3e84f57 317 Pfam PF01522 Polysaccharide deacetylase 146 245 6.7E-29 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_02120 bbb247a25399ae1153a28c23ff8ddcc2 248 PIRSF PIRSF039085 1 244 5.8E-100 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 UP12_02120 bbb247a25399ae1153a28c23ff8ddcc2 248 Gene3D G3DSA:3.40.50.300 1 248 4.4E-75 T 11-10-2018 UP12_02120 bbb247a25399ae1153a28c23ff8ddcc2 248 SUPERFAMILY SSF52540 1 238 8.96E-74 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02120 bbb247a25399ae1153a28c23ff8ddcc2 248 Pfam PF00005 ABC transporter 17 168 3.1E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_02120 bbb247a25399ae1153a28c23ff8ddcc2 248 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_02120 bbb247a25399ae1153a28c23ff8ddcc2 248 SMART SM00382 26 216 3.1E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_10675 22744685993f261b967ad074aafa8869 159 Pfam PF00583 Acetyltransferase (GNAT) family 31 123 1.2E-16 T 11-10-2018 IPR000182 GNAT domain UP12_10675 22744685993f261b967ad074aafa8869 159 SUPERFAMILY SSF55729 1 155 4.49E-26 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_10675 22744685993f261b967ad074aafa8869 159 PIRSF PIRSF037663 1 157 1.3E-69 T 11-10-2018 IPR017255 Acetyltransferase, GNAT, predicted UP12_10675 22744685993f261b967ad074aafa8869 159 Gene3D G3DSA:3.40.630.30 1 155 8.2E-44 T 11-10-2018 UP12_09625 c6fbc80728a2090dcb8f70b0cb65ca60 83 ProDom PD710533 YODI TRANSMEMBRANE MEMBRANE 2 83 2.0E-11 T 11-10-2018 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 PRINTS PR00412 Epoxide hydrolase signature 33 51 3.5E-23 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 PRINTS PR00412 Epoxide hydrolase signature 53 68 3.5E-23 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 PRINTS PR00412 Epoxide hydrolase signature 100 113 3.5E-23 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 PRINTS PR00412 Epoxide hydrolase signature 262 284 3.5E-23 T 11-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 Pfam PF00561 alpha/beta hydrolase fold 27 274 2.2E-23 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 Gene3D G3DSA:3.40.50.1820 5 286 1.3E-81 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_01540 e397a9e24eef41538cad49dd7506696d 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 4.0E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 4.0E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 231 245 4.0E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 UP12_01540 e397a9e24eef41538cad49dd7506696d 286 SUPERFAMILY SSF53474 3 286 3.87E-72 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_14855 98db84cdd62d94f2e19641b343d335e9 205 SUPERFAMILY SSF53098 5 176 9.34E-30 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily UP12_14855 98db84cdd62d94f2e19641b343d335e9 205 Pfam PF00929 Exonuclease 7 173 2.9E-22 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UP12_14855 98db84cdd62d94f2e19641b343d335e9 205 Gene3D G3DSA:3.30.420.10 2 201 2.8E-39 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 UP12_14855 98db84cdd62d94f2e19641b343d335e9 205 SMART SM00479 5 182 3.6E-31 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III UP12_17400 d67d764dee06c934c719f76076cd3ab7 703 SUPERFAMILY SSF103501 6 238 3.66E-17 T 11-10-2018 IPR036197 NarG-like superfamily UP12_17400 d67d764dee06c934c719f76076cd3ab7 703 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 371 382 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site UP12_17400 d67d764dee06c934c719f76076cd3ab7 703 SUPERFAMILY SSF46548 253 399 2.62E-20 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 UP12_17400 d67d764dee06c934c719f76076cd3ab7 703 Pfam PF02754 Cysteine-rich domain 581 668 2.9E-17 T 11-10-2018 IPR004017 Cysteine-rich domain UP12_17400 d67d764dee06c934c719f76076cd3ab7 703 Pfam PF02754 Cysteine-rich domain 458 537 5.4E-6 T 11-10-2018 IPR004017 Cysteine-rich domain UP12_17400 d67d764dee06c934c719f76076cd3ab7 703 Pfam PF13183 4Fe-4S dicluster domain 274 383 1.8E-12 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain UP12_12660 2c1a32ed8a56604fd27898e2f6a000b0 170 Pfam PF05119 Phage terminase, small subunit 52 157 7.9E-27 T 11-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family UP12_12660 2c1a32ed8a56604fd27898e2f6a000b0 170 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 43 166 8.0E-29 T 11-10-2018 IPR006448 Putative phage terminase, small subunit, P27 family UP12_18880 52c20dc6425120671b8f1df4a3f5e2a6 287 Pfam PF09648 YycH protein 38 270 7.0E-54 T 11-10-2018 IPR018604 Regulatory protein YycH-like GO:0016021 UP12_18880 52c20dc6425120671b8f1df4a3f5e2a6 287 Gene3D G3DSA:3.30.310.160 70 195 5.7E-66 T 11-10-2018 UP12_18880 52c20dc6425120671b8f1df4a3f5e2a6 287 Gene3D G3DSA:3.10.450.660 47 272 5.7E-66 T 11-10-2018 UP12_02705 5e1527d298b4322f1abaabd5730f188d 321 Pfam PF02486 Replication initiation factor 96 296 1.8E-63 T 11-10-2018 IPR003491 Replication initiation factor GO:0003677|GO:0003916|GO:0006270 UP12_01675 22ef9eb83afe1214c22b51b006e142d3 364 Pfam PF05816 Toxic anion resistance protein (TelA) 35 359 1.6E-106 T 11-10-2018 IPR008863 Toxic anion resistance UP12_01675 22ef9eb83afe1214c22b51b006e142d3 364 PIRSF PIRSF026508 1 364 2.3E-127 T 11-10-2018 IPR008863 Toxic anion resistance UP12_07450 870557df9646f4d5d4d8ab9bcc3419a1 143 Pfam PF06923 Glucitol operon activator protein (GutM) 4 114 4.3E-26 T 11-10-2018 IPR009693 Glucitol operon activator UP12_05290 3e27baa8d87eb4476603d4861f709da3 379 Pfam PF05145 Transition state regulatory protein AbrB 31 364 4.0E-88 T 11-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 UP12_05290 3e27baa8d87eb4476603d4861f709da3 379 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 9 171 7.9E-35 T 11-10-2018 IPR017516 AbrB duplication UP12_05290 3e27baa8d87eb4476603d4861f709da3 379 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 203 364 1.3E-34 T 11-10-2018 IPR017516 AbrB duplication UP12_05290 3e27baa8d87eb4476603d4861f709da3 379 PIRSF PIRSF038991 1 372 7.6E-88 T 11-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 UP12_07585 8c560df2e492064dbc4aac9b70eadcb3 354 Pfam PF01384 Phosphate transporter family 16 305 5.0E-44 T 11-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 UP12_09455 2fac9fb40d1089f668bb56a2f1785e9d 478 Gene3D G3DSA:3.30.1330.120 283 421 2.3E-185 T 11-10-2018 UP12_09455 2fac9fb40d1089f668bb56a2f1785e9d 478 Gene3D G3DSA:1.10.4100.10 23 456 2.3E-185 T 11-10-2018 UP12_09455 2fac9fb40d1089f668bb56a2f1785e9d 478 Pfam PF03972 MmgE/PrpD family 15 459 9.0E-147 T 11-10-2018 IPR005656 MmgE/PrpD GO:0016829 UP12_09455 2fac9fb40d1089f668bb56a2f1785e9d 478 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 11 478 1.8E-246 T 11-10-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 UP12_09455 2fac9fb40d1089f668bb56a2f1785e9d 478 SUPERFAMILY SSF103378 10 477 1.57E-149 T 11-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 UP12_15150 cf784f81be19fe6261bd00d015221b65 78 Pfam PF07293 Protein of unknown function (DUF1450) 2 75 1.0E-35 T 11-10-2018 IPR009910 Protein of unknown function DUF1450 UP12_15150 cf784f81be19fe6261bd00d015221b65 78 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 1 77 1.0E-27 T 11-10-2018 UP12_07905 6ae921969c321fe23286fe4e0bf0bb93 254 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 1 253 1.0E-108 T 11-10-2018 IPR022524 Flagellar assembly FliH, Bacilli UP12_07905 6ae921969c321fe23286fe4e0bf0bb93 254 Pfam PF02108 Flagellar assembly protein FliH 115 240 8.5E-14 T 11-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE UP12_05395 53d652d645930f3774296436b50d69c6 175 Pfam PF10949 Protein of unknown function (DUF2777) 2 171 1.6E-51 T 11-10-2018 IPR024488 Protein of unknown function DUF2777 UP12_05395 53d652d645930f3774296436b50d69c6 175 ProDom PD106196 YISN IG BH1722 3 169 1.0E-27 T 11-10-2018 IPR024488 Protein of unknown function DUF2777 UP12_17935 7c3a0006e57a49b85a9b576565239e30 254 SMART SM00079 34 254 5.7E-7 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 UP12_17935 7c3a0006e57a49b85a9b576565239e30 254 Gene3D G3DSA:3.40.190.10 118 213 7.0E-78 T 11-10-2018 UP12_17935 7c3a0006e57a49b85a9b576565239e30 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 253 1.5E-68 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_17935 7c3a0006e57a49b85a9b576565239e30 254 Gene3D G3DSA:3.40.190.10 37 251 7.0E-78 T 11-10-2018 UP12_17935 7c3a0006e57a49b85a9b576565239e30 254 SUPERFAMILY SSF53850 1 253 2.18E-75 T 11-10-2018 UP12_17935 7c3a0006e57a49b85a9b576565239e30 254 SMART SM00062 34 254 4.5E-70 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF UP12_04415 48a5d8e2135e21c88fe89b595981440b 298 SUPERFAMILY SSF161098 89 281 3.38E-32 T 11-10-2018 IPR035906 MetI-like superfamily UP12_04415 48a5d8e2135e21c88fe89b595981440b 298 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 62 1.4E-9 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain UP12_04415 48a5d8e2135e21c88fe89b595981440b 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 296 2.5E-33 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_04415 48a5d8e2135e21c88fe89b595981440b 298 Gene3D G3DSA:1.10.3720.10 83 296 2.4E-27 T 11-10-2018 IPR035906 MetI-like superfamily UP12_17710 4005486506a3ca5be817e54b1e9eb55e 435 Pfam PF00860 Permease family 2 390 1.4E-71 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 UP12_08185 84955838cdb7838ace370cd6bd5e6b11 300 SUPERFAMILY SSF51735 141 248 1.32E-16 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_08185 84955838cdb7838ace370cd6bd5e6b11 300 Gene3D G3DSA:3.40.50.720 126 272 1.0E-103 T 11-10-2018 UP12_08185 84955838cdb7838ace370cd6bd5e6b11 300 Gene3D G3DSA:3.40.50.720 7 285 1.0E-103 T 11-10-2018 UP12_08185 84955838cdb7838ace370cd6bd5e6b11 300 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 5 289 9.8E-132 T 11-10-2018 IPR014215 Dipicolinic acid synthetase subunit A UP12_08185 84955838cdb7838ace370cd6bd5e6b11 300 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 6 123 2.8E-29 T 11-10-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal UP12_08185 84955838cdb7838ace370cd6bd5e6b11 300 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 152 294 1.4E-8 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain UP12_04190 ae389494cc7d37c10dc9fc321bc4164f 209 SUPERFAMILY SSF52266 2 204 1.12E-50 T 11-10-2018 UP12_04190 ae389494cc7d37c10dc9fc321bc4164f 209 Gene3D G3DSA:3.40.50.1110 2 209 8.4E-64 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_04190 ae389494cc7d37c10dc9fc321bc4164f 209 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 191 6.8E-13 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain UP12_13915 6e0f1cbfda82bf34be90c2adb0193b7e 472 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 117 466 8.5E-112 T 11-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 UP12_13915 6e0f1cbfda82bf34be90c2adb0193b7e 472 Gene3D G3DSA:3.60.120.10 2 469 4.3E-112 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_13915 6e0f1cbfda82bf34be90c2adb0193b7e 472 Hamap MF_01935 Isochorismate synthase MenF [menF]. 5 468 31.286 T 11-10-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 UP12_13915 6e0f1cbfda82bf34be90c2adb0193b7e 472 SUPERFAMILY SSF56322 48 467 3.79E-102 T 11-10-2018 IPR005801 ADC synthase GO:0009058 UP12_13915 6e0f1cbfda82bf34be90c2adb0193b7e 472 Pfam PF00425 chorismate binding enzyme 206 458 1.1E-74 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal UP12_13575 2114603481c5b0860508144be335b2f0 174 Pfam PF03691 Uncharacterised protein family (UPF0167) 3 173 8.2E-67 T 11-10-2018 IPR005363 Uncharacterised protein family UPF0167 UP12_18140 32f8b2fc267f8706943bf6704bedbc1d 284 Gene3D G3DSA:3.20.20.370 60 281 3.9E-67 T 11-10-2018 UP12_18140 32f8b2fc267f8706943bf6704bedbc1d 284 Pfam PF01522 Polysaccharide deacetylase 121 245 9.6E-35 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 UP12_18140 32f8b2fc267f8706943bf6704bedbc1d 284 SUPERFAMILY SSF88713 84 266 3.95E-45 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 UP12_00950 cc1efe95cfa4c5669ad3a09b2522687d 200 SMART SM01251 17 195 6.1E-115 T 11-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 UP12_00950 cc1efe95cfa4c5669ad3a09b2522687d 200 PIRSF PIRSF029886 1 198 1.3E-84 T 11-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 UP12_00950 cc1efe95cfa4c5669ad3a09b2522687d 200 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 194 3.4E-74 T 11-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 UP12_05840 b02aa9c401b2626bcc6ca099ce8f9e48 268 Pfam PF08543 Phosphomethylpyrimidine kinase 13 257 1.9E-94 T 11-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 UP12_05840 b02aa9c401b2626bcc6ca099ce8f9e48 268 SUPERFAMILY SSF53613 1 262 3.59E-81 T 11-10-2018 IPR029056 Ribokinase-like UP12_05840 b02aa9c401b2626bcc6ca099ce8f9e48 268 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 259 1.3E-100 T 11-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 UP12_05840 b02aa9c401b2626bcc6ca099ce8f9e48 268 Gene3D G3DSA:3.40.1190.20 1 267 8.7E-101 T 11-10-2018 IPR029056 Ribokinase-like UP12_01365 95231c82c42b4a462c9ffe80f889ba32 539 Pfam PF13520 Amino acid permease 9 425 1.1E-48 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_01365 95231c82c42b4a462c9ffe80f889ba32 539 Gene3D G3DSA:1.20.1740.10 1 458 2.4E-78 T 11-10-2018 UP12_01365 95231c82c42b4a462c9ffe80f889ba32 539 PIRSF PIRSF006060 1 460 8.9E-74 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_01365 95231c82c42b4a462c9ffe80f889ba32 539 PIRSF PIRSF006060 430 531 200.0 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_05240 529bab22cffae37a67ac8f95dcecc2ce 192 Pfam PF06338 ComK protein 10 158 1.2E-62 T 11-10-2018 IPR010461 Competence protein ComK GO:0030420 UP12_05240 529bab22cffae37a67ac8f95dcecc2ce 192 PIRSF PIRSF011560 5 191 4.3E-71 T 11-10-2018 IPR010461 Competence protein ComK GO:0030420 UP12_08980 4d1afa5e6f7616da787dc2b2cb4b6e6f 421 Pfam PF17189 Glycosyl hydrolase family 30 beta sandwich domain 330 417 1.8E-6 T 11-10-2018 IPR033452 Glycosyl hydrolase family 30, beta sandwich domain Reactome: R-HSA-1660662|Reactome: R-HSA-390471 UP12_08980 4d1afa5e6f7616da787dc2b2cb4b6e6f 421 Gene3D G3DSA:3.20.20.80 48 329 4.9E-169 T 11-10-2018 UP12_08980 4d1afa5e6f7616da787dc2b2cb4b6e6f 421 Gene3D G3DSA:2.60.40.1180 37 418 4.9E-169 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta UP12_08980 4d1afa5e6f7616da787dc2b2cb4b6e6f 421 SUPERFAMILY SSF51445 47 329 8.04E-50 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily UP12_08980 4d1afa5e6f7616da787dc2b2cb4b6e6f 421 SUPERFAMILY SSF51011 325 420 1.87E-24 T 11-10-2018 UP12_06165 344607cc1b12477ba43937501a41aaea 256 ProDom PD120066 SPORULATION STAGE SA II SPOIISA TRANSMEMBRANE MEMBRANE KILLER 15 241 1.0E-88 T 11-10-2018 UP12_06165 344607cc1b12477ba43937501a41aaea 256 Gene3D G3DSA:1.20.5.460 92 127 2.7E-15 T 11-10-2018 UP12_06165 344607cc1b12477ba43937501a41aaea 256 Pfam PF14171 Toxin SpoIISA, type II toxin-antitoxin system 3 238 3.1E-93 T 11-10-2018 IPR025940 Toxin SpoIISA, type II toxin-antitoxin system GO:0009405|GO:0016021 UP12_06165 344607cc1b12477ba43937501a41aaea 256 Gene3D G3DSA:3.30.70.2720 128 248 8.9E-39 T 11-10-2018 UP12_11735 6842a55d3ef471c640493e5c0960b97a 97 Pfam PF11122 Inner spore coat protein D 22 85 2.5E-16 T 11-10-2018 IPR020108 Spore coat protein CotD UP12_13305 d4b7e345d72a826d99120ff0a5deae6f 204 Pfam PF01810 LysE type translocator 15 201 1.5E-28 T 11-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UP12_08865 1659ee249aa9eab8645bffaccfa03d14 193 Pfam PF02525 Flavodoxin-like fold 3 191 8.2E-33 T 11-10-2018 IPR003680 Flavodoxin-like fold UP12_08865 1659ee249aa9eab8645bffaccfa03d14 193 Gene3D G3DSA:3.40.50.360 3 193 1.8E-41 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08865 1659ee249aa9eab8645bffaccfa03d14 193 SUPERFAMILY SSF52218 4 192 2.73E-38 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_00930 1ca367862926404393bca8b79f31779c 147 Pfam PF10730 Protein of unknown function (DUF2521) 1 147 1.7E-53 T 11-10-2018 IPR019667 Uncharacterised protein family YbaK UP12_03300 92f4af065772e2730d1de79933604e51 185 Gene3D G3DSA:3.40.630.30 11 178 3.6E-45 T 11-10-2018 UP12_03300 92f4af065772e2730d1de79933604e51 185 Pfam PF13302 Acetyltransferase (GNAT) domain 17 156 1.0E-28 T 11-10-2018 IPR000182 GNAT domain UP12_03300 92f4af065772e2730d1de79933604e51 185 SUPERFAMILY SSF55729 9 181 2.36E-48 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_18420 fa471062819b9e4402d91d1fc150a17a 235 Gene3D G3DSA:3.40.50.150 6 230 2.8E-35 T 11-10-2018 UP12_18420 fa471062819b9e4402d91d1fc150a17a 235 SUPERFAMILY SSF53335 7 221 2.17E-28 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_18420 fa471062819b9e4402d91d1fc150a17a 235 Pfam PF13649 Methyltransferase domain 48 142 2.2E-13 T 11-10-2018 UP12_03450 dade253ca82ae508fa9953bfb190c9a5 526 Gene3D G3DSA:3.20.20.70 117 517 3.4E-101 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_03450 dade253ca82ae508fa9953bfb190c9a5 526 SUPERFAMILY SSF51395 10 512 5.76E-110 T 11-10-2018 UP12_03450 dade253ca82ae508fa9953bfb190c9a5 526 PIRSF PIRSF500060 1 524 1.5E-212 T 11-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria UP12_03450 dade253ca82ae508fa9953bfb190c9a5 526 Pfam PF01645 Conserved region in glutamate synthase 118 493 4.1E-114 T 11-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 UP12_03450 dade253ca82ae508fa9953bfb190c9a5 526 PIRSF PIRSF006429 1 525 1.2E-162 T 11-10-2018 IPR024188 Glutamate synthase large subunit-like protein UP12_08490 f47fea374e7edb3bef20d1b8a8e56b0d 426 Gene3D G3DSA:3.90.1150.60 17 412 1.3E-183 T 11-10-2018 UP12_08490 f47fea374e7edb3bef20d1b8a8e56b0d 426 SUPERFAMILY SSF53383 50 399 1.86E-47 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase UP12_08490 f47fea374e7edb3bef20d1b8a8e56b0d 426 Gene3D G3DSA:3.40.640.10 58 272 1.3E-183 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 UP12_08490 f47fea374e7edb3bef20d1b8a8e56b0d 426 Pfam PF06838 Methionine gamma-lyase 13 415 2.9E-211 T 11-10-2018 IPR009651 Putative methionine gamma-lyase UP12_17075 f3cc219df5c5ebe4bb87c949e95bf460 176 SUPERFAMILY SSF52833 11 160 7.17E-13 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_17075 f3cc219df5c5ebe4bb87c949e95bf460 176 Pfam PF00578 AhpC/TSA family 47 157 4.5E-8 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 UP12_17075 f3cc219df5c5ebe4bb87c949e95bf460 176 Gene3D G3DSA:3.40.30.10 29 175 2.1E-14 T 11-10-2018 UP12_03050 638854c02b2eda7f8896d194faab9b17 61 Pfam PF05532 CsbD-like 9 59 2.3E-16 T 11-10-2018 IPR008462 CsbD-like domain UP12_03050 638854c02b2eda7f8896d194faab9b17 61 SUPERFAMILY SSF69047 9 58 1.7E-11 T 11-10-2018 IPR036629 YjbJ superfamily UP12_03050 638854c02b2eda7f8896d194faab9b17 61 Gene3D G3DSA:1.10.1470.10 7 61 3.2E-10 T 11-10-2018 IPR036629 YjbJ superfamily UP12_04745 d76c653bb0bcebd0c3cda884be163f27 302 Pfam PF00849 RNA pseudouridylate synthase 91 243 2.3E-33 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_04745 d76c653bb0bcebd0c3cda884be163f27 302 SUPERFAMILY SSF55120 75 298 4.32E-66 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_04745 d76c653bb0bcebd0c3cda884be163f27 302 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 19 299 4.3E-80 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 UP12_04745 d76c653bb0bcebd0c3cda884be163f27 302 Gene3D G3DSA:3.30.2350.10 84 302 5.9E-66 T 11-10-2018 UP12_06335 f381dfdb57a7ec272b4a18f885142464 250 SUPERFAMILY SSF158560 3 72 1.44E-12 T 11-10-2018 UP12_11485 d1a8571f924d6438195dd5104cce1aa9 159 Pfam PF02130 Uncharacterized protein family UPF0054 15 152 7.5E-49 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UP12_11485 d1a8571f924d6438195dd5104cce1aa9 159 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 123 133 - T 11-10-2018 IPR020549 Endoribonuclease YbeY, conserved site UP12_11485 d1a8571f924d6438195dd5104cce1aa9 159 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 157 24.117 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UP12_11485 d1a8571f924d6438195dd5104cce1aa9 159 Gene3D G3DSA:3.40.390.30 2 159 2.8E-48 T 11-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 UP12_11485 d1a8571f924d6438195dd5104cce1aa9 159 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 40 154 4.5E-42 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 UP12_11485 d1a8571f924d6438195dd5104cce1aa9 159 SUPERFAMILY SSF55486 2 157 6.35E-46 T 11-10-2018 UP12_00230 7218136de4b823f8e6d7ac77572cb715 117 Hamap MF_01159 Initiation-control protein YabA. 1 116 25.535 T 11-10-2018 IPR010377 Initiation control protein YabA GO:0006260 UP12_00230 7218136de4b823f8e6d7ac77572cb715 117 Pfam PF06156 Initiation control protein YabA 1 112 3.3E-39 T 11-10-2018 IPR010377 Initiation control protein YabA GO:0006260 UP12_00230 7218136de4b823f8e6d7ac77572cb715 117 PIRSF PIRSF021439 1 117 2.2E-43 T 11-10-2018 IPR010377 Initiation control protein YabA GO:0006260 UP12_04990 2d204e4d5bc16846e3992459b3922aae 377 PIRSF PIRSF032178 1 377 4.9E-127 T 11-10-2018 IPR016991 Protein of unknown function UCP032178 UP12_04990 2d204e4d5bc16846e3992459b3922aae 377 Pfam PF04286 Protein of unknown function (DUF445) 12 376 2.1E-79 T 11-10-2018 IPR007383 Protein of unknown function DUF445 UP12_08000 573b600d9865cfe4b4b5b566807b3fd5 301 PIRSF PIRSF003092 3 299 1.1E-81 T 11-10-2018 IPR025501 ATP binding protein MinD UP12_08000 573b600d9865cfe4b4b5b566807b3fd5 301 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 32 271 2.8E-17 T 11-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 UP12_08000 573b600d9865cfe4b4b5b566807b3fd5 301 Gene3D G3DSA:3.40.50.300 31 271 1.1E-57 T 11-10-2018 UP12_08000 573b600d9865cfe4b4b5b566807b3fd5 301 SUPERFAMILY SSF52540 31 276 4.84E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_14440 456b74bb3165b93930e5bf9363ad478e 306 Pfam PF03837 RecT family 45 238 4.0E-45 T 11-10-2018 IPR018330 RecT family GO:0003677|GO:0006259 UP12_14440 456b74bb3165b93930e5bf9363ad478e 306 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 56 209 2.3E-17 T 11-10-2018 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 UP12_09620 e96b54ba5aeb2a47f77416a0467cdb77 232 Pfam PF08241 Methyltransferase domain 40 132 5.4E-19 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 UP12_09620 e96b54ba5aeb2a47f77416a0467cdb77 232 Gene3D G3DSA:3.40.50.150 4 232 3.0E-42 T 11-10-2018 UP12_09620 e96b54ba5aeb2a47f77416a0467cdb77 232 SUPERFAMILY SSF53335 12 196 7.55E-40 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_08845 5f2cbf4230dbdcd9012d5949c2adcf7b 237 Gene3D G3DSA:3.40.30.10 1 208 7.2E-69 T 11-10-2018 UP12_08845 5f2cbf4230dbdcd9012d5949c2adcf7b 237 SUPERFAMILY SSF52833 1 212 6.58E-44 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_08845 5f2cbf4230dbdcd9012d5949c2adcf7b 237 Pfam PF01323 DSBA-like thioredoxin domain 2 205 4.4E-42 T 11-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 UP12_10805 f34a3849385f5d77364fc6016dcda4ac 330 Pfam PF00795 Carbon-nitrogen hydrolase 9 278 2.8E-54 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 UP12_10805 f34a3849385f5d77364fc6016dcda4ac 330 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 40 55 - T 11-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 UP12_10805 f34a3849385f5d77364fc6016dcda4ac 330 SUPERFAMILY SSF56317 6 287 2.49E-63 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UP12_10805 f34a3849385f5d77364fc6016dcda4ac 330 Gene3D G3DSA:3.60.110.10 1 282 4.4E-94 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UP12_07480 4599afda773f96865727c901b0d99d31 263 SUPERFAMILY SSF64438 13 261 2.01E-80 T 11-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic UP12_07480 4599afda773f96865727c901b0d99d31 263 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 258 7.9E-73 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase UP12_07480 4599afda773f96865727c901b0d99d31 263 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 26 260 8.7E-63 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase UP12_07480 4599afda773f96865727c901b0d99d31 263 Gene3D G3DSA:3.60.140.10 3 263 4.2E-90 T 11-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily UP12_07495 11f19f399d4718889557c812d40d9513 93 Pfam PF02325 YGGT family 12 78 5.4E-23 T 11-10-2018 IPR003425 CCB3/YggT GO:0016020 UP12_11495 eefa3782e826a28f1da5acf4c0e07c7b 319 Pfam PF02562 PhoH-like protein 113 316 4.0E-95 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 UP12_11495 eefa3782e826a28f1da5acf4c0e07c7b 319 SUPERFAMILY SSF52540 66 279 1.14E-38 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_11495 eefa3782e826a28f1da5acf4c0e07c7b 319 Gene3D G3DSA:3.40.50.300 109 316 1.7E-75 T 11-10-2018 UP12_16530 25bb4013dae4bb3b899d930382b28a1b 509 Pfam PF07196 Flagellin hook IN motif 122 183 1.1E-7 T 11-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 UP12_16530 25bb4013dae4bb3b899d930382b28a1b 509 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 12 105 2.3E-25 T 11-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 UP12_16530 25bb4013dae4bb3b899d930382b28a1b 509 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 222 498 2.7E-49 T 11-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 UP12_06200 acd15a421008a3d416bf6a6e30a23aa2 92 SUPERFAMILY SSF52794 3 90 4.5E-19 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 UP12_06200 acd15a421008a3d416bf6a6e30a23aa2 92 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 76 2.3E-14 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 UP12_06200 acd15a421008a3d416bf6a6e30a23aa2 92 Gene3D G3DSA:3.40.50.2300 2 92 1.3E-28 T 11-10-2018 UP12_13365 8c1d29fbcb5d79adcbc3d905802a57df 115 SUPERFAMILY SSF49842 17 90 2.07E-5 T 11-10-2018 IPR008983 Tumour necrosis factor-like domain superfamily GO:0005515 UP12_10790 6565b2e63fb103fc15e1638eb3b186b4 294 SUPERFAMILY SSF103481 200 292 9.55E-6 T 11-10-2018 UP12_10790 6565b2e63fb103fc15e1638eb3b186b4 294 SUPERFAMILY SSF103481 48 150 2.62E-8 T 11-10-2018 UP12_10790 6565b2e63fb103fc15e1638eb3b186b4 294 Pfam PF06800 Sugar transport protein 16 292 3.5E-94 T 11-10-2018 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 UP12_18320 19392832da86b1e71708c4cdb8314b26 228 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 13 215 1.8E-55 T 11-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 UP12_18320 19392832da86b1e71708c4cdb8314b26 228 SUPERFAMILY SSF48613 3 222 7.57E-66 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UP12_18320 19392832da86b1e71708c4cdb8314b26 228 Pfam PF03070 TENA/THI-4/PQQC family 11 214 5.1E-46 T 11-10-2018 IPR004305 Thiaminase-2/PQQC UP12_18320 19392832da86b1e71708c4cdb8314b26 228 Gene3D G3DSA:1.20.910.10 1 224 3.6E-66 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 UP12_19110 cb5a659bc0842f4bd9f4a3a4358aa941 68 Pfam PF06107 Bacterial protein of unknown function (DUF951) 7 59 3.8E-30 T 11-10-2018 IPR009296 Protein of unknown function DUF951 UP12_19110 cb5a659bc0842f4bd9f4a3a4358aa941 68 PIRSF PIRSF037263 1 66 8.0E-35 T 11-10-2018 IPR009296 Protein of unknown function DUF951 UP12_07185 d678f86225c1a4c9c16d44d61fcf4f38 403 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 10 372 4.1E-103 T 11-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07185 d678f86225c1a4c9c16d44d61fcf4f38 403 Pfam PF01098 Cell cycle protein 14 375 3.2E-113 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07185 d678f86225c1a4c9c16d44d61fcf4f38 403 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 333 357 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_04760 0d946ae72e191519944759708448b47a 512 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 374 394 - T 11-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site UP12_04760 0d946ae72e191519944759708448b47a 512 Gene3D G3DSA:3.40.630.30 6 225 2.7E-61 T 11-10-2018 UP12_04760 0d946ae72e191519944759708448b47a 512 Pfam PF00583 Acetyltransferase (GNAT) family 26 145 3.7E-12 T 11-10-2018 IPR000182 GNAT domain UP12_04760 0d946ae72e191519944759708448b47a 512 Gene3D G3DSA:3.60.110.10 227 512 7.8E-59 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UP12_04760 0d946ae72e191519944759708448b47a 512 Pfam PF00795 Carbon-nitrogen hydrolase 232 488 1.9E-30 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 UP12_04760 0d946ae72e191519944759708448b47a 512 SUPERFAMILY SSF56317 228 495 1.22E-59 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily UP12_04760 0d946ae72e191519944759708448b47a 512 SUPERFAMILY SSF55729 16 144 6.0E-18 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_02230 ce5ae5fd998837fa058c87ad469b4910 97 Pfam PF17247 Family of unknown function (DUF5316) 31 96 1.3E-17 T 11-10-2018 IPR035167 Protein of unknown function DUF5316 UP12_07205 c0dbe886aecfe7cce02f4fab937dc684 305 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 21 304 18.239 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 UP12_07205 c0dbe886aecfe7cce02f4fab937dc684 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 81 103 - T 11-10-2018 IPR030470 UbiA prenyltransferase conserved site UP12_07205 c0dbe886aecfe7cce02f4fab937dc684 305 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 23 301 8.5E-96 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 UP12_07205 c0dbe886aecfe7cce02f4fab937dc684 305 Pfam PF01040 UbiA prenyltransferase family 39 288 4.9E-59 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 UP12_07205 c0dbe886aecfe7cce02f4fab937dc684 305 Gene3D G3DSA:1.10.357.140 33 190 4.5E-18 T 11-10-2018 UP12_07155 45844984c568816f7993678a6febc06b 76 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 2.6E-30 T 11-10-2018 IPR019241 Protein of unknown function DUF2197 UP12_13210 7c385e85dadc1ad1f604e08de5c22b5d 150 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 3 134 3.7E-58 T 11-10-2018 IPR014229 Sporulation protein YtfJ UP12_13210 7c385e85dadc1ad1f604e08de5c22b5d 150 PIRSF PIRSF021377 1 149 1.1E-62 T 11-10-2018 IPR014229 Sporulation protein YtfJ UP12_13210 7c385e85dadc1ad1f604e08de5c22b5d 150 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 125 3.5E-29 T 11-10-2018 IPR014229 Sporulation protein YtfJ UP12_08930 dfea5b1a6b8b1c1c24fa03cded0c985a 103 Pfam PF08803 Putative mono-oxygenase ydhR 4 99 8.1E-43 T 11-10-2018 IPR014910 Putative monooxygenase YdhR UP12_08930 dfea5b1a6b8b1c1c24fa03cded0c985a 103 Gene3D G3DSA:3.30.70.100 1 103 1.0E-42 T 11-10-2018 UP12_08930 dfea5b1a6b8b1c1c24fa03cded0c985a 103 SUPERFAMILY SSF54909 3 96 8.94E-33 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel UP12_18845 96755a968e6fd478146362952ba11036 185 Gene3D G3DSA:1.10.1760.20 1 176 4.9E-23 T 11-10-2018 UP12_18845 96755a968e6fd478146362952ba11036 185 Hamap MF_01572 UPF0397 protein . 4 183 26.711 T 11-10-2018 IPR022914 Protein of unknown function UPF0397 UP12_18845 96755a968e6fd478146362952ba11036 185 Pfam PF07155 ECF-type riboflavin transporter, S component 6 172 8.6E-53 T 11-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 UP12_08125 1a9493255d394c6b3df26cf9956ebc2d 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 95 7.9E-19 T 11-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 UP12_08125 1a9493255d394c6b3df26cf9956ebc2d 100 SUPERFAMILY SSF55315 6 99 1.26E-25 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_08125 1a9493255d394c6b3df26cf9956ebc2d 100 Gene3D G3DSA:3.30.1330.30 2 100 2.9E-40 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like UP12_02555 1c25aceb928ccd067e6410ec75c2b76a 122 SUPERFAMILY SSF52091 6 116 1.28E-20 T 11-10-2018 IPR036513 STAS domain superfamily UP12_02555 1c25aceb928ccd067e6410ec75c2b76a 122 Gene3D G3DSA:3.30.750.24 4 120 3.0E-33 T 11-10-2018 IPR036513 STAS domain superfamily UP12_02555 1c25aceb928ccd067e6410ec75c2b76a 122 Pfam PF01740 STAS domain 13 101 1.3E-12 T 11-10-2018 IPR002645 STAS domain UP12_09255 97070a0dcc7f1705f20c5818bccc0122 186 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 93 121 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 UP12_09255 97070a0dcc7f1705f20c5818bccc0122 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 119 3.5E-8 T 11-10-2018 IPR001451 Hexapeptide repeat UP12_09255 97070a0dcc7f1705f20c5818bccc0122 186 SUPERFAMILY SSF51161 33 174 9.84E-40 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily UP12_09255 97070a0dcc7f1705f20c5818bccc0122 186 Gene3D G3DSA:2.160.10.10 2 185 1.7E-53 T 11-10-2018 UP12_16400 025199a8dd9dc021aec6e6815d8214aa 190 Gene3D G3DSA:1.10.357.10 3 182 4.2E-20 T 11-10-2018 UP12_16400 025199a8dd9dc021aec6e6815d8214aa 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 8.8E-15 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_16400 025199a8dd9dc021aec6e6815d8214aa 190 SUPERFAMILY SSF46689 5 58 7.18E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_16400 025199a8dd9dc021aec6e6815d8214aa 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 8.8E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_16400 025199a8dd9dc021aec6e6815d8214aa 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 8.8E-9 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_02370 97923fbebdc0fdd630f2accaa315460e 571 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 216 479 1.3E-46 T 11-10-2018 IPR018763 Protein of unknown function DUF2334 UP12_15595 8d66c448d6fd3ca76beff974099e522d 497 Gene3D G3DSA:3.90.1210.30 3 85 3.1E-30 T 11-10-2018 UP12_15595 8d66c448d6fd3ca76beff974099e522d 497 Pfam PF08666 SAF domain 11 82 8.6E-14 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UP12_15595 8d66c448d6fd3ca76beff974099e522d 497 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 108 496 6.4E-156 T 11-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 UP12_15595 8d66c448d6fd3ca76beff974099e522d 497 SMART SM00858 11 82 7.1E-13 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 UP12_11425 1b9bb4abd450b9e72e48aff293353f3f 119 SUPERFAMILY SSF46626 6 117 1.31E-14 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UP12_11425 1b9bb4abd450b9e72e48aff293353f3f 119 Gene3D G3DSA:1.10.760.10 50 119 7.8E-23 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 UP12_11425 1b9bb4abd450b9e72e48aff293353f3f 119 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 48 115 1.7E-11 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 UP12_11425 1b9bb4abd450b9e72e48aff293353f3f 119 PIRSF PIRSF000025 1 119 5.5E-37 T 11-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 UP12_18770 3fdc53c162bb07a4e30a7692c0177f9b 288 Gene3D G3DSA:3.60.15.10 5 243 7.6E-37 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_18770 3fdc53c162bb07a4e30a7692c0177f9b 288 SUPERFAMILY SSF56281 26 241 3.93E-40 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like UP12_18770 3fdc53c162bb07a4e30a7692c0177f9b 288 Pfam PF00753 Metallo-beta-lactamase superfamily 28 222 1.5E-19 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_18770 3fdc53c162bb07a4e30a7692c0177f9b 288 SMART SM00849 23 222 5.9E-21 T 11-10-2018 IPR001279 Metallo-beta-lactamase UP12_04995 e6768da039b533849c71de1403ac35fc 118 Hamap MF_01526 UPF0342 protein . 2 113 19.253 T 11-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA UP12_04995 e6768da039b533849c71de1403ac35fc 118 Gene3D G3DSA:1.20.1500.10 2 113 9.4E-39 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily UP12_04995 e6768da039b533849c71de1403ac35fc 118 SUPERFAMILY SSF158622 3 114 8.37E-39 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily UP12_04995 e6768da039b533849c71de1403ac35fc 118 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 108 1.3E-23 T 11-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA UP12_13640 2f8ae5d8e47a66b1719f462c9cd9fff4 292 SUPERFAMILY SSF161098 8 292 1.31E-60 T 11-10-2018 IPR035906 MetI-like superfamily UP12_13640 2f8ae5d8e47a66b1719f462c9cd9fff4 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 284 3.5E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_13640 2f8ae5d8e47a66b1719f462c9cd9fff4 292 Gene3D G3DSA:1.10.3720.10 3 283 1.7E-73 T 11-10-2018 IPR035906 MetI-like superfamily UP12_08870 c905fabea7b99186a6987a5c0aac2f98 114 Pfam PF01638 HxlR-like helix-turn-helix 23 113 8.9E-29 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_08870 c905fabea7b99186a6987a5c0aac2f98 114 Gene3D G3DSA:1.10.10.10 2 114 2.4E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_08870 c905fabea7b99186a6987a5c0aac2f98 114 SUPERFAMILY SSF46785 16 112 1.37E-27 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_07140 3ae3658554365a4b0b4f95745ef4a241 59 Pfam PF17259 Family of unknown function (DUF5325) 1 55 1.6E-18 T 11-10-2018 IPR035211 Protein of unknown function DUF5325 UP12_07140 3ae3658554365a4b0b4f95745ef4a241 59 ProDom PD699877 YLAF TRANSMEMBRANE MEMBRANE BH2633 1 56 3.0E-4 T 11-10-2018 IPR035211 Protein of unknown function DUF5325 UP12_01215 91270eeac14b19dd8f53f179b4961842 252 Pfam PF13349 Putative adhesin 49 225 6.5E-9 T 11-10-2018 IPR025164 Putative adhesin UP12_01530 f9ca6133d1ddfd2f2d638706c0a3a2ff 460 Gene3D G3DSA:1.20.1740.10 20 459 3.2E-124 T 11-10-2018 UP12_01530 f9ca6133d1ddfd2f2d638706c0a3a2ff 460 PIRSF PIRSF006060 11 459 2.3E-86 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_01530 f9ca6133d1ddfd2f2d638706c0a3a2ff 460 Pfam PF13520 Amino acid permease 27 427 3.1E-60 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_05970 4736ccb557585bd353f69eb58b8ecfbd 407 SUPERFAMILY SSF103473 15 393 4.58E-48 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_05970 4736ccb557585bd353f69eb58b8ecfbd 407 Pfam PF07690 Major Facilitator Superfamily 37 363 4.0E-23 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_05970 4736ccb557585bd353f69eb58b8ecfbd 407 Gene3D G3DSA:1.20.1250.20 215 396 2.2E-19 T 11-10-2018 UP12_05970 4736ccb557585bd353f69eb58b8ecfbd 407 Gene3D G3DSA:1.20.1250.20 14 210 9.3E-14 T 11-10-2018 UP12_06930 7f79152788ded13824ce14ff9a0c5f0b 163 SUPERFAMILY SSF54690 4 137 1.31E-47 T 11-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 UP12_06930 7f79152788ded13824ce14ff9a0c5f0b 163 Gene3D G3DSA:3.90.1170.40 2 146 4.3E-55 T 11-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 UP12_06930 7f79152788ded13824ce14ff9a0c5f0b 163 Pfam PF02391 MoaE protein 7 118 1.6E-38 T 11-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 UP12_14525 108a31956e8690f03171e672a0f25608 46 Pfam PF09693 Phage uncharacterised protein (Phage_XkdX) 7 44 2.1E-13 T 11-10-2018 IPR010022 Protein of unknown function XkdX UP12_14525 108a31956e8690f03171e672a0f25608 46 TIGRFAM TIGR01669 phage_XkdX: phage uncharacterized protein, XkdX family 2 44 1.1E-9 T 11-10-2018 IPR010022 Protein of unknown function XkdX UP12_14285 abbe7c9f0d7c0777362d7bc8bbe944bc 294 Pfam PF10668 Phage terminase small subunit 1 60 7.2E-24 T 11-10-2018 IPR018925 Phage terminase small subunit UP12_17020 48395e9037d4ca57810a7e0b3c6ae8dd 137 Gene3D G3DSA:1.10.10.10 1 137 2.7E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_17020 48395e9037d4ca57810a7e0b3c6ae8dd 137 SMART SM00347 25 124 5.7E-29 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_17020 48395e9037d4ca57810a7e0b3c6ae8dd 137 Pfam PF01047 MarR family 32 88 1.3E-15 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_17020 48395e9037d4ca57810a7e0b3c6ae8dd 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 1.9E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_17020 48395e9037d4ca57810a7e0b3c6ae8dd 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 1.9E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 UP12_17020 48395e9037d4ca57810a7e0b3c6ae8dd 137 SUPERFAMILY SSF46785 3 135 8.7E-31 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_14515 10e87ab790acfc75b55b06521bc612c4 87 Pfam PF04688 SPP1 phage holin 3 82 3.7E-31 T 11-10-2018 IPR006479 Holin UP12_14515 10e87ab790acfc75b55b06521bc612c4 87 TIGRFAM TIGR01592 holin_SPP1: holin, SPP1 family 5 85 5.0E-29 T 11-10-2018 IPR006479 Holin UP12_14515 10e87ab790acfc75b55b06521bc612c4 87 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 4 87 9.0E-33 T 11-10-2018 IPR006479 Holin UP12_00820 7488ad827be33eb09b2df882a7552c89 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 8.6E-57 T 11-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 UP12_00820 7488ad827be33eb09b2df882a7552c89 146 Gene3D G3DSA:3.100.10.10 66 146 6.9E-29 T 11-10-2018 UP12_00820 7488ad827be33eb09b2df882a7552c89 146 SUPERFAMILY SSF52080 4 143 7.85E-51 T 11-10-2018 IPR036227 Ribosomal L18e/L15P superfamily UP12_00820 7488ad827be33eb09b2df882a7552c89 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 11-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 UP12_00820 7488ad827be33eb09b2df882a7552c89 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 1.1E-39 T 11-10-2018 IPR021131 Ribosomal protein L18e/L15P UP12_00820 7488ad827be33eb09b2df882a7552c89 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 23.13 T 11-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 UP12_06610 1605848aca84416ae8062a7bc32a2dbf 264 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 217 1.7E-26 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel UP12_06610 1605848aca84416ae8062a7bc32a2dbf 264 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 11-10-2018 IPR000540 Flagellar motor protein MotA, conserved site UP12_08270 88f65c5eee2e6949490de6d370a40293 85 Gene3D G3DSA:1.10.760.20 1 82 3.6E-31 T 11-10-2018 IPR038292 YmfJ/YflH superfamily UP12_08270 88f65c5eee2e6949490de6d370a40293 85 Pfam PF11588 Protein of unknown function (DUF3243) 2 80 1.0E-34 T 11-10-2018 IPR021637 Protein of unknown function DUF3243 UP12_08270 88f65c5eee2e6949490de6d370a40293 85 PIRSF PIRSF004764 1 85 7.0E-28 T 11-10-2018 IPR024702 Uncharacterised conserved protein YmfJ UP12_15580 a1da2ad93a6bada700cd5e39d6cbdf68 352 Pfam PF01032 FecCD transport family 23 344 4.6E-93 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_15580 a1da2ad93a6bada700cd5e39d6cbdf68 352 Gene3D G3DSA:1.10.3470.10 9 351 3.5E-99 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_15580 a1da2ad93a6bada700cd5e39d6cbdf68 352 SUPERFAMILY SSF81345 9 344 2.88E-80 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_16070 613dc91819cbf642fec0e1acbea2b075 74 TIGRFAM TIGR01592 holin_SPP1: holin, SPP1 family 6 72 1.5E-27 T 11-10-2018 IPR006479 Holin UP12_16070 613dc91819cbf642fec0e1acbea2b075 74 ProDom PD008023 HOLIN TRANSMEMBRANE MEMBRANE PROPHAGE FAMILY BHLB SPP1 5'REGION HOLIN ORF050 6 69 8.0E-15 T 11-10-2018 IPR006479 Holin UP12_16070 613dc91819cbf642fec0e1acbea2b075 74 Pfam PF04688 SPP1 phage holin 5 72 4.1E-27 T 11-10-2018 IPR006479 Holin UP12_12345 35f4c26d7f03cae80e8bcab62bf059b6 263 Pfam PF02602 Uroporphyrinogen-III synthase HemD 24 251 6.0E-50 T 11-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12345 35f4c26d7f03cae80e8bcab62bf059b6 263 Gene3D G3DSA:3.40.50.10090 153 259 9.4E-21 T 11-10-2018 UP12_12345 35f4c26d7f03cae80e8bcab62bf059b6 263 SUPERFAMILY SSF69618 9 257 2.88E-62 T 11-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 UP12_12345 35f4c26d7f03cae80e8bcab62bf059b6 263 Gene3D G3DSA:3.40.50.10090 6 133 2.6E-25 T 11-10-2018 UP12_01580 5885ad4677c437879dfe219472b45cf3 321 Pfam PF14501 GHKL domain 209 314 4.8E-12 T 11-10-2018 IPR032834 Sensor histidine kinase NatK, C-terminal domain UP12_01580 5885ad4677c437879dfe219472b45cf3 321 SUPERFAMILY SSF55874 174 317 5.5E-14 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_01580 5885ad4677c437879dfe219472b45cf3 321 Gene3D G3DSA:3.30.565.10 168 316 6.4E-18 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily UP12_01580 5885ad4677c437879dfe219472b45cf3 321 SMART SM00387 210 320 3.0E-6 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase UP12_04265 76ae4287f23be0e36888fb5e34345a16 155 Pfam PF04134 Protein of unknown function, DUF393 32 138 7.4E-12 T 11-10-2018 IPR007263 Protein of unknown function DUF393 UP12_16460 b08bdae438a0ddeb1e9a74e4d587f9c6 421 Gene3D G3DSA:1.20.5.340 29 131 9.9E-7 T 11-10-2018 UP12_16460 b08bdae438a0ddeb1e9a74e4d587f9c6 421 Gene3D G3DSA:2.70.70.10 245 421 8.5E-39 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_16460 b08bdae438a0ddeb1e9a74e4d587f9c6 421 SUPERFAMILY SSF57997 36 119 1.67E-7 T 11-10-2018 UP12_16460 b08bdae438a0ddeb1e9a74e4d587f9c6 421 Pfam PF01551 Peptidase family M23 313 416 2.7E-29 T 11-10-2018 IPR016047 Peptidase M23 UP12_16460 b08bdae438a0ddeb1e9a74e4d587f9c6 421 SUPERFAMILY SSF51261 252 420 4.13E-45 T 11-10-2018 IPR011055 Duplicated hybrid motif UP12_12525 3bfbc181af01a73cca2071e2c4a300b6 353 SMART SM00909 92 181 4.0E-21 T 11-10-2018 IPR019606 GerMN domain UP12_12525 3bfbc181af01a73cca2071e2c4a300b6 353 SMART SM00909 242 333 2.0E-23 T 11-10-2018 IPR019606 GerMN domain UP12_12525 3bfbc181af01a73cca2071e2c4a300b6 353 Pfam PF10646 Sporulation and spore germination 69 177 2.7E-20 T 11-10-2018 IPR019606 GerMN domain UP12_12525 3bfbc181af01a73cca2071e2c4a300b6 353 Pfam PF10646 Sporulation and spore germination 214 327 3.1E-18 T 11-10-2018 IPR019606 GerMN domain UP12_10075 14376e18235b67694dafb8c6803e37e6 234 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 4 226 1.7E-100 T 11-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 UP12_10075 14376e18235b67694dafb8c6803e37e6 234 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 123 4.1E-23 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 UP12_10075 14376e18235b67694dafb8c6803e37e6 234 Gene3D G3DSA:3.40.50.10320 1 234 1.5E-82 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UP12_10075 14376e18235b67694dafb8c6803e37e6 234 SUPERFAMILY SSF102588 4 230 6.02E-55 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 UP12_02160 d65a0855396f6c240c1b98cd6b645e05 103 SUPERFAMILY SSF46785 5 91 1.29E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_02160 d65a0855396f6c240c1b98cd6b645e05 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.2E-13 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_02160 d65a0855396f6c240c1b98cd6b645e05 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 1.2E-13 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_02160 d65a0855396f6c240c1b98cd6b645e05 103 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 1.2E-13 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_02160 d65a0855396f6c240c1b98cd6b645e05 103 SMART SM00418 16 93 1.4E-22 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 UP12_02160 d65a0855396f6c240c1b98cd6b645e05 103 Pfam PF12840 Helix-turn-helix domain 17 69 3.8E-12 T 11-10-2018 UP12_02160 d65a0855396f6c240c1b98cd6b645e05 103 Gene3D G3DSA:1.10.10.10 2 94 1.7E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_05360 52f4140cab936fbf36c7e7a4796ab81c 77 Pfam PF10803 Spore germination GerPB 1 52 1.0E-28 T 11-10-2018 IPR024255 Spore germination GerPB UP12_05360 52f4140cab936fbf36c7e7a4796ab81c 77 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 55 1.0E-19 T 11-10-2018 IPR024255 Spore germination GerPB UP12_13435 5a9b9c98ca5700f122adb8d926db96a4 139 Pfam PF06103 Bacterial protein of unknown function (DUF948) 8 95 2.3E-27 T 11-10-2018 IPR009293 Uncharacterised protein family UPF0478 UP12_13435 5a9b9c98ca5700f122adb8d926db96a4 139 SUPERFAMILY SSF58104 27 128 2.22E-5 T 11-10-2018 UP12_13435 5a9b9c98ca5700f122adb8d926db96a4 139 Gene3D G3DSA:1.10.287.950 20 137 1.0E-5 T 11-10-2018 UP12_12445 fe8a7cfa472e1f819bfd17bd88851fa0 139 PIRSF PIRSF031804 1 122 3.6E-38 T 11-10-2018 IPR016983 Uncharacterised conserved protein UCP031804 UP12_12445 fe8a7cfa472e1f819bfd17bd88851fa0 139 Pfam PF06803 Protein of unknown function (DUF1232) 57 93 7.4E-14 T 11-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 UP12_05460 97b6324f400a713df6dc42bd7d25ff34 593 Pfam PF06276 Ferric iron reductase FhuF-like transporter 409 568 2.0E-39 T 11-10-2018 IPR022770 Ferric iron reductase FhuF domain UP12_05460 97b6324f400a713df6dc42bd7d25ff34 593 Pfam PF04183 IucA / IucC family 144 378 2.4E-58 T 11-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 UP12_05460 97b6324f400a713df6dc42bd7d25ff34 593 Gene3D G3DSA:1.10.510.40 372 573 1.7E-14 T 11-10-2018 UP12_01910 d7a77dcbd52b63700bfa10c291494372 410 Gene3D G3DSA:1.10.10.2840 277 410 6.3E-15 T 11-10-2018 UP12_01910 d7a77dcbd52b63700bfa10c291494372 410 Pfam PF13556 PucR C-terminal helix-turn-helix domain 348 403 1.4E-17 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_01510 f37624a616d364e7a2a9455e415387ae 340 SUPERFAMILY SSF51182 38 291 1.17E-31 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily UP12_01510 f37624a616d364e7a2a9455e415387ae 340 Gene3D G3DSA:2.60.120.10 15 314 6.9E-79 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_01510 f37624a616d364e7a2a9455e415387ae 340 Gene3D G3DSA:2.60.120.10 23 194 6.9E-79 T 11-10-2018 IPR014710 RmlC-like jelly roll fold UP12_01510 f37624a616d364e7a2a9455e415387ae 340 Pfam PF07883 Cupin domain 55 111 2.5E-13 T 11-10-2018 IPR013096 Cupin 2, conserved barrel UP12_01510 f37624a616d364e7a2a9455e415387ae 340 Pfam PF07883 Cupin domain 228 285 5.9E-13 T 11-10-2018 IPR013096 Cupin 2, conserved barrel UP12_04420 464addea26863e9298df7ebd7d46926c 357 Pfam PF06081 Aromatic acid exporter family member 1 1 142 2.5E-41 T 11-10-2018 IPR010343 Aromatic acid exporter family member 1 UP12_00280 9c2f15badd68c6b4f50b30be02854c9b 294 Pfam PF05582 YabG peptidase U57 4 286 7.3E-118 T 11-10-2018 IPR008764 Peptidase U57, YabG UP12_00280 9c2f15badd68c6b4f50b30be02854c9b 294 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 4 287 2.2E-140 T 11-10-2018 IPR008764 Peptidase U57, YabG UP12_00280 9c2f15badd68c6b4f50b30be02854c9b 294 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 4 283 2.0E-128 T 11-10-2018 IPR008764 Peptidase U57, YabG UP12_00280 9c2f15badd68c6b4f50b30be02854c9b 294 PIRSF PIRSF011575 2 291 3.1E-131 T 11-10-2018 IPR008764 Peptidase U57, YabG UP12_10890 b57a040d7fc2f929b71c7ca0b1f26bf8 330 Gene3D G3DSA:3.40.50.970 2 330 5.1E-117 T 11-10-2018 UP12_10890 b57a040d7fc2f929b71c7ca0b1f26bf8 330 Pfam PF00676 Dehydrogenase E1 component 20 319 3.6E-106 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 UP12_10890 b57a040d7fc2f929b71c7ca0b1f26bf8 330 SUPERFAMILY SSF52518 6 330 2.27E-101 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold UP12_11150 12bb0ce54aff4e386357acb43eb9fbc6 108 Gene3D G3DSA:3.10.450.390 26 108 2.0E-26 T 11-10-2018 UP12_11150 12bb0ce54aff4e386357acb43eb9fbc6 108 Pfam PF13028 Protein of unknown function (DUF3889) 13 105 1.0E-32 T 11-10-2018 IPR024987 Protein of unknown function DUF3889 UP12_17155 188766963b7f9aa4054d5737da674b66 435 Gene3D G3DSA:3.65.10.10 21 231 1.2E-173 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UP12_17155 188766963b7f9aa4054d5737da674b66 435 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 2.8E-121 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 UP12_17155 188766963b7f9aa4054d5737da674b66 435 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.518 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_17155 188766963b7f9aa4054d5737da674b66 435 Gene3D G3DSA:3.65.10.10 7 414 1.2E-173 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 UP12_17155 188766963b7f9aa4054d5737da674b66 435 SUPERFAMILY SSF55205 2 418 1.49E-141 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 UP12_17155 188766963b7f9aa4054d5737da674b66 435 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 2.2E-180 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 UP12_08350 5bc6034b047d5ba64786b22c717c0c8d 181 Pfam PF10628 Outer spore coat protein E (CotE) 3 176 3.8E-68 T 11-10-2018 IPR018901 Spore coat protein CotE UP12_03175 f86b32690b7adf5d4dd05db5c51ab081 64 ProDom PD053380 YDIK LIPOPROTEIN TRANSMEMBRANE MEMBRANE PRECURSOR PALMITATE SIGNAL 1 63 2.0E-22 T 11-10-2018 UP12_03175 f86b32690b7adf5d4dd05db5c51ab081 64 Pfam PF14146 Domain of unknown function (DUF4305) 17 52 8.1E-15 T 11-10-2018 IPR025426 Protein of unknown function DUF4305 UP12_12020 3bea996355f68b31b8a8b97e43c64d66 152 SUPERFAMILY SSF50346 82 128 1.12E-5 T 11-10-2018 IPR011033 PRC-barrel-like superfamily UP12_01605 a785ddc33c452e3fcb57384c752d98e0 352 Pfam PF11611 Domain of unknown function (DUF4352) 33 147 4.7E-24 T 11-10-2018 IPR029051 Domain of unknown function DUF4352 UP12_01605 a785ddc33c452e3fcb57384c752d98e0 352 Pfam PF17118 Domain of unknown function (DUF5105) 162 350 2.0E-72 T 11-10-2018 IPR031343 Domain of unknown function DUF5105 UP12_01605 a785ddc33c452e3fcb57384c752d98e0 352 Gene3D G3DSA:2.60.40.1240 34 168 5.1E-16 T 11-10-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain superfamily UP12_11045 f2525d8c79c4b5d29c042bdff7d6d7d2 307 Gene3D G3DSA:3.40.50.300 117 264 7.9E-24 T 11-10-2018 UP12_11045 f2525d8c79c4b5d29c042bdff7d6d7d2 307 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 292 6.6E-122 T 11-10-2018 IPR014217 Sporulation stage III, protein AA UP12_11045 f2525d8c79c4b5d29c042bdff7d6d7d2 307 SMART SM00382 135 272 7.3E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_11045 f2525d8c79c4b5d29c042bdff7d6d7d2 307 SUPERFAMILY SSF52540 47 260 4.21E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_14450 a5b0312c73be5e15bf1dd0f121ea6f87 72 Gene3D G3DSA:3.30.40.30 2 72 2.0E-13 T 11-10-2018 IPR023118 YqaI domain superfamily UP12_14450 a5b0312c73be5e15bf1dd0f121ea6f87 72 Pfam PF09466 Hypothetical protein Yqai 28 72 2.0E-10 T 11-10-2018 IPR018474 Uncharacterised protein family YqaI UP12_14450 a5b0312c73be5e15bf1dd0f121ea6f87 72 SUPERFAMILY SSF160713 2 71 1.03E-16 T 11-10-2018 IPR023118 YqaI domain superfamily UP12_16980 7356dff80a9f8eed2bbb2fa6e6354cc6 136 Pfam PF14183 YwpF-like protein 2 134 5.0E-48 T 11-10-2018 IPR025573 YwpF-like protein UP12_03065 c69b373c7d6390e37636022163d9f66e 241 Pfam PF03591 AzlC protein 26 166 1.2E-39 T 11-10-2018 IPR011606 Branched-chain amino acid transport, permease UP12_04305 7308b13cd5d17c1fa1bf426975ee5093 49 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 49 17.307 T 11-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 UP12_04305 7308b13cd5d17c1fa1bf426975ee5093 49 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 16 47 6.3E-19 T 11-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 UP12_04305 7308b13cd5d17c1fa1bf426975ee5093 49 Pfam PF08176 Small acid-soluble spore protein K family 1 47 2.1E-28 T 11-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 UP12_14615 e0889b22be3f06cc3baede484f55276f 118 ProDom PD031312 YQBH LIN1274 PHAGE XKDH PHAGE-LIKE PBSX RELATED ELEMENT 1 114 5.0E-37 T 11-10-2018 IPR024556 Protein of unknown function DUF3599 UP12_14615 e0889b22be3f06cc3baede484f55276f 118 Gene3D G3DSA:2.40.10.370 1 118 5.6E-43 T 11-10-2018 IPR038667 XkdH-like superfamily UP12_14615 e0889b22be3f06cc3baede484f55276f 118 Pfam PF12206 Domain of unknown function (DUF3599) 1 116 4.9E-58 T 11-10-2018 IPR024556 Protein of unknown function DUF3599 UP12_00925 c12768c4f171ef31805e96d32cfb5106 189 Pfam PF16107 Domain of unknown function (DUF4825) 40 138 1.0E-14 T 11-10-2018 IPR032250 Domain of unknown function DUF4825 UP12_17850 bbd3819745f10116a70fd65df6f97753 127 Pfam PF04138 GtrA-like protein 2 119 8.2E-28 T 11-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 UP12_08215 9569126e4344f7b7f17e64b6f1844fe8 242 Gene3D G3DSA:3.90.226.10 40 219 2.1E-30 T 11-10-2018 UP12_08215 9569126e4344f7b7f17e64b6f1844fe8 242 SUPERFAMILY SSF52096 27 225 1.96E-38 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily UP12_08215 9569126e4344f7b7f17e64b6f1844fe8 242 Pfam PF00574 Clp protease 41 217 1.6E-33 T 11-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA UP12_08895 79ea27b88693a1fea58c9c6d7d1c6e2f 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 60 3.1E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08895 79ea27b88693a1fea58c9c6d7d1c6e2f 226 SUPERFAMILY SSF46689 19 79 1.55E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_08895 79ea27b88693a1fea58c9c6d7d1c6e2f 226 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 82 223 9.3E-13 T 11-10-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 UP12_08895 79ea27b88693a1fea58c9c6d7d1c6e2f 226 SUPERFAMILY SSF48498 87 223 2.22E-19 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily UP12_08895 79ea27b88693a1fea58c9c6d7d1c6e2f 226 Gene3D G3DSA:1.10.357.10 3 226 1.3E-58 T 11-10-2018 UP12_17255 101f7ef78e23b37983c243cc80263483 147 SUPERFAMILY SSF55729 3 125 7.88E-8 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_17255 101f7ef78e23b37983c243cc80263483 147 Gene3D G3DSA:3.40.630.30 4 144 1.6E-8 T 11-10-2018 UP12_07365 f772c8816871bc1f85092b55f0e9760f 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 2.6E-5 T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07365 f772c8816871bc1f85092b55f0e9760f 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07365 f772c8816871bc1f85092b55f0e9760f 324 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07365 f772c8816871bc1f85092b55f0e9760f 324 Pfam PF00953 Glycosyl transferase family 4 82 248 3.0E-39 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 UP12_07365 f772c8816871bc1f85092b55f0e9760f 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 323 9.7E-132 T 11-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_07365 f772c8816871bc1f85092b55f0e9760f 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.968 T 11-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 UP12_16405 aa9966df03d74aa5ee4e6ad152b7d479 444 Pfam PF07690 Major Facilitator Superfamily 13 190 8.7E-37 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_16405 aa9966df03d74aa5ee4e6ad152b7d479 444 Pfam PF07690 Major Facilitator Superfamily 263 429 1.4E-18 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_16405 aa9966df03d74aa5ee4e6ad152b7d479 444 Gene3D G3DSA:1.20.1720.10 9 214 9.3E-50 T 11-10-2018 UP12_16405 aa9966df03d74aa5ee4e6ad152b7d479 444 Gene3D G3DSA:1.20.1250.20 250 437 5.4E-25 T 11-10-2018 UP12_16405 aa9966df03d74aa5ee4e6ad152b7d479 444 SUPERFAMILY SSF103473 8 432 5.23E-67 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_09275 ef61267aa37368662d307f5ad1c285fc 231 Gene3D G3DSA:3.30.240.20 167 229 4.9E-17 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily UP12_09275 ef61267aa37368662d307f5ad1c285fc 231 Pfam PF04239 Protein of unknown function (DUF421) 88 203 1.1E-31 T 11-10-2018 IPR007353 Protein of unknown function DUF421 UP12_09275 ef61267aa37368662d307f5ad1c285fc 231 Gene3D G3DSA:3.30.240.20 79 153 3.1E-21 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily UP12_02995 70383791f29e1d38a58e9e15505db748 183 Gene3D G3DSA:1.10.357.10 2 175 1.9E-39 T 11-10-2018 UP12_02995 70383791f29e1d38a58e9e15505db748 183 Pfam PF14278 Transcriptional regulator C-terminal region 86 157 3.6E-13 T 11-10-2018 IPR039532 Transcriptional regulator TetR, C-terminal, Firmicutes type UP12_02995 70383791f29e1d38a58e9e15505db748 183 SUPERFAMILY SSF46689 3 69 3.69E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_12610 8fd3802da617e67348648a4978ddd8e7 132 Pfam PF11367 Protein of unknown function (DUF3168) 16 107 1.3E-9 T 11-10-2018 IPR021508 Tail completion protein UP12_11145 2f30b836e3bbe1ac6f3b8fe02f400b1c 175 TIGRFAM TIGR04087 YqxM_for_SipW: YqxM protein 5 173 2.5E-51 T 11-10-2018 IPR023848 TasA anchoring/assembly protein GO:0062039 UP12_11145 2f30b836e3bbe1ac6f3b8fe02f400b1c 175 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 12 44 2.9E-5 T 11-10-2018 IPR023833 Signal peptide, camelysin UP12_03840 a53b3e808a31d2a89539ac756bb6ea6b 267 Gene3D G3DSA:3.90.1580.10 2 266 3.3E-49 T 11-10-2018 UP12_03840 a53b3e808a31d2a89539ac756bb6ea6b 267 SUPERFAMILY SSF56436 3 256 8.24E-56 T 11-10-2018 IPR016187 C-type lectin fold UP12_03840 a53b3e808a31d2a89539ac756bb6ea6b 267 Pfam PF03781 Sulfatase-modifying factor enzyme 1 39 256 6.0E-41 T 11-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 UP12_13830 9476bbda95a96332bba569ae7989aeef 48 Pfam PF12606 Tumour necrosis factor receptor superfamily member 19 1 42 6.9E-9 T 11-10-2018 IPR022248 TNF receptor family, RELT UP12_16755 5465c15ec4926d3a54bbb211645fcc5e 273 SUPERFAMILY SSF161098 4 273 1.21E-64 T 11-10-2018 IPR035906 MetI-like superfamily UP12_16755 5465c15ec4926d3a54bbb211645fcc5e 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 266 1.7E-18 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 UP12_16755 5465c15ec4926d3a54bbb211645fcc5e 273 Gene3D G3DSA:1.10.3720.10 2 264 1.9E-53 T 11-10-2018 IPR035906 MetI-like superfamily UP12_15810 b0df1c2c2b9c5c650a84d2c884859289 248 PIRSF PIRSF017388 1 246 5.8E-99 T 11-10-2018 IPR012354 Esterase/lipase GO:0052689 UP12_15810 b0df1c2c2b9c5c650a84d2c884859289 248 Gene3D G3DSA:3.40.50.1820 1 246 6.3E-63 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_15810 b0df1c2c2b9c5c650a84d2c884859289 248 Pfam PF12146 Serine aminopeptidase, S33 16 229 2.1E-18 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 UP12_15810 b0df1c2c2b9c5c650a84d2c884859289 248 SUPERFAMILY SSF53474 12 245 5.7E-37 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13010 0981949312cb4375b6605d16932e803d 212 Pfam PF09335 SNARE associated Golgi protein 61 177 1.7E-23 T 11-10-2018 IPR032816 SNARE associated Golgi protein UP12_09235 06c537797476e8968ee15a1e0ad2fce9 206 Pfam PF01184 GPR1/FUN34/yaaH family 11 194 2.1E-25 T 11-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 UP12_01760 8252425bb247d9d64bec9ff8519b73f0 252 Pfam PF08892 YqcI/YcgG family 31 244 7.0E-79 T 11-10-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG UP12_18295 a12584f008c9224b909acfc2cd4f59e9 271 SUPERFAMILY SSF103032 6 271 6.41E-81 T 11-10-2018 IPR035948 YwqG-like superfamily UP12_18295 a12584f008c9224b909acfc2cd4f59e9 271 Pfam PF09234 Domain of unknown function (DUF1963) 40 270 2.6E-65 T 11-10-2018 IPR015315 Protein of unknown function DUF1963 UP12_18295 a12584f008c9224b909acfc2cd4f59e9 271 Gene3D G3DSA:2.30.320.10 2 271 3.6E-98 T 11-10-2018 IPR035948 YwqG-like superfamily UP12_18040 48e225e5fc3146e41e8b713de41cb7ae 345 SMART SM00656 62 282 1.1E-30 T 11-10-2018 IPR002022 Pectate lyase UP12_18040 48e225e5fc3146e41e8b713de41cb7ae 345 Gene3D G3DSA:2.160.20.10 46 344 5.9E-103 T 11-10-2018 IPR012334 Pectin lyase fold UP12_18040 48e225e5fc3146e41e8b713de41cb7ae 345 SUPERFAMILY SSF51126 49 343 4.09E-80 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor UP12_18040 48e225e5fc3146e41e8b713de41cb7ae 345 Pfam PF00544 Pectate lyase 111 276 1.8E-34 T 11-10-2018 IPR002022 Pectate lyase UP12_15470 e205236ed1a0ab4946911aca3103435f 115 Pfam PF07875 Coat F domain 23 85 4.6E-22 T 11-10-2018 IPR012851 Spore coat protein CotF-like UP12_01535 ecc28561626d4a8981ac8ff63f1ddd98 121 SUPERFAMILY SSF54593 1 120 5.49E-23 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_01535 ecc28561626d4a8981ac8ff63f1ddd98 121 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 111 1.2E-5 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain UP12_01535 ecc28561626d4a8981ac8ff63f1ddd98 121 Gene3D G3DSA:3.10.180.10 1 121 1.6E-21 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase UP12_08520 f6a0baf8437cac3def1d51f83d255ff0 625 Pfam PF04740 LXG domain of WXG superfamily 2 201 2.6E-48 T 11-10-2018 IPR006829 LXG domain UP12_09245 5b3b6eb5ce2b22640314ccf6a2fdf1af 1305 Pfam PF01391 Collagen triple helix repeat (20 copies) 1115 1173 9.1E-8 T 11-10-2018 IPR008160 Collagen triple helix repeat UP12_09245 5b3b6eb5ce2b22640314ccf6a2fdf1af 1305 Pfam PF01391 Collagen triple helix repeat (20 copies) 182 238 1.4E-6 T 11-10-2018 IPR008160 Collagen triple helix repeat UP12_09245 5b3b6eb5ce2b22640314ccf6a2fdf1af 1305 Pfam PF01391 Collagen triple helix repeat (20 copies) 73 129 5.5E-8 T 11-10-2018 IPR008160 Collagen triple helix repeat UP12_09245 5b3b6eb5ce2b22640314ccf6a2fdf1af 1305 Pfam PF01391 Collagen triple helix repeat (20 copies) 116 170 1.1E-6 T 11-10-2018 IPR008160 Collagen triple helix repeat UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 2.0E-15 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.0E-15 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 2.0E-15 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 2.0E-15 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 147 2.2E-41 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 SMART SM00226 2 149 8.8E-50 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 SUPERFAMILY SSF52788 1 150 2.75E-47 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily UP12_03995 2da82c55eb9e53d0a37f10b6f4a7b7df 156 Gene3D G3DSA:3.40.50.2300 1 156 2.9E-60 T 11-10-2018 UP12_10340 78816ab8aa9d06180bdaa67623e2779f 150 ProDom PD089241 YPBF MEMBRANE BH1610 TRANSMEMBRANE 16 148 1.0E-31 T 11-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane UP12_10340 78816ab8aa9d06180bdaa67623e2779f 150 Pfam PF10864 Protein of unknown function (DUF2663) 17 148 4.1E-46 T 11-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane UP12_09465 b38bcb961447e7730e07fef8ea50146e 179 Pfam PF04238 Protein of unknown function (DUF420) 46 174 2.9E-46 T 11-10-2018 IPR007352 Protein of unknown function DUF420 UP12_14570 78b9ed894a02428030cb6b4908c1fd15 336 SUPERFAMILY SSF69279 19 150 6.23E-8 T 11-10-2018 UP12_17550 e0a1cfb0f379f6a789c95695a490c1fe 136 ProDom PD338809 BH2346 YXIB BH4015 BH0976 PREFOLDIN 11 115 8.0E-23 T 11-10-2018 UP12_17550 e0a1cfb0f379f6a789c95695a490c1fe 136 Pfam PF16888 Domain of unknown function (DUF5082) 14 120 1.0E-13 T 11-10-2018 IPR031681 Protein of unknown function DUF5082 UP12_09100 e49521bc1ade24b5de1239363ecd9068 141 Pfam PF04657 Putative inner membrane exporter, YdcZ 4 138 5.3E-32 T 11-10-2018 IPR006750 Putative inner membrane exporter, YdcZ UP12_11880 aa576d7d2f0019a9b523879cc2de00bd 84 Pfam PF14143 YrhC-like protein 11 82 2.0E-31 T 11-10-2018 IPR025418 YrhC-like protein UP12_11880 aa576d7d2f0019a9b523879cc2de00bd 84 ProDom PD057834 YRHC TRANSMEMBRANE MEMBRANE 10 83 5.0E-17 T 11-10-2018 IPR025418 YrhC-like protein UP12_05680 aa8e388c9a9400033cfabfdb114285e7 250 Pfam PF12227 Protein of unknown function (DUF3603) 35 250 8.7E-111 T 11-10-2018 IPR020909 UPF0736 UP12_05680 aa8e388c9a9400033cfabfdb114285e7 250 Hamap MF_01860 UPF0736 protein . 1 250 49.096 T 11-10-2018 IPR020909 UPF0736 UP12_14620 b37cb67d2d5d29bdb6870bb799218f1f 127 Pfam PF11436 Protein of unknown function (DUF3199) 2 125 4.6E-58 T 11-10-2018 IPR013514 Protein of unknown function DUF3199, YqbG UP12_14620 b37cb67d2d5d29bdb6870bb799218f1f 127 SUPERFAMILY SSF116915 1 126 5.23E-53 T 11-10-2018 IPR036558 YqbG-like superfamily UP12_14620 b37cb67d2d5d29bdb6870bb799218f1f 127 Gene3D G3DSA:1.10.3230.10 1 127 2.1E-48 T 11-10-2018 IPR036558 YqbG-like superfamily UP12_06830 0bad7d89efdbef979e0535cab4ddab05 171 Pfam PF04308 Ribonuclease H-like 18 171 2.5E-53 T 11-10-2018 IPR007405 Bacteriophage KVP40, Orf299 UP12_01930 c4f2a58950cc858e349be1cf4e072446 109 Pfam PF10925 Protein of unknown function (DUF2680) 41 97 2.9E-24 T 11-10-2018 IPR024485 Protein of unknown function DUF2680 UP12_01930 c4f2a58950cc858e349be1cf4e072446 109 ProDom PD673109 PRECURSOR SIGNAL YCKD ORF4 DOMAIN 39 99 8.0E-15 T 11-10-2018 IPR024485 Protein of unknown function DUF2680 UP12_07300 f609301a2a4ae055e5954f818beb2fb0 414 Pfam PF05636 HIGH Nucleotidyl Transferase 2 389 1.5E-136 T 11-10-2018 IPR008513 Uncharacterised protein family UPF0348 UP12_07300 f609301a2a4ae055e5954f818beb2fb0 414 Hamap MF_01539 UPF0348 protein . 2 404 39.856 T 11-10-2018 IPR008513 Uncharacterised protein family UPF0348 UP12_07300 f609301a2a4ae055e5954f818beb2fb0 414 SUPERFAMILY SSF52374 9 238 6.62E-18 T 11-10-2018 UP12_07300 f609301a2a4ae055e5954f818beb2fb0 414 Gene3D G3DSA:3.40.50.620 1 172 7.6E-38 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold UP12_16995 ed09ecb502b3fc3fb7eb481852590ee4 351 Pfam PF13424 Tetratricopeptide repeat 175 238 3.5E-9 T 11-10-2018 UP12_16995 ed09ecb502b3fc3fb7eb481852590ee4 351 Gene3D G3DSA:1.25.40.10 2 350 3.6E-73 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_16995 ed09ecb502b3fc3fb7eb481852590ee4 351 SUPERFAMILY SSF48452 88 254 1.76E-13 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 UP12_17730 c70abeff698c5e144b0f85cfcc7981dc 275 SUPERFAMILY SSF53448 2 208 1.31E-42 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_17730 c70abeff698c5e144b0f85cfcc7981dc 275 Gene3D G3DSA:3.90.550.10 1 228 2.8E-36 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_17730 c70abeff698c5e144b0f85cfcc7981dc 275 Pfam PF00535 Glycosyl transferase family 2 4 163 2.8E-24 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 UP12_05305 63e9d219615756170f88b4682ccb1657 136 Pfam PF07681 DoxX 9 87 1.3E-18 T 11-10-2018 IPR032808 DoxX family UP12_01590 2fb6bc1005ad40789dda7201af3d52de 246 SMART SM00382 30 215 3.2E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_01590 2fb6bc1005ad40789dda7201af3d52de 246 Gene3D G3DSA:3.40.50.300 1 244 6.5E-67 T 11-10-2018 UP12_01590 2fb6bc1005ad40789dda7201af3d52de 246 SUPERFAMILY SSF52540 2 228 2.43E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_01590 2fb6bc1005ad40789dda7201af3d52de 246 Pfam PF00005 ABC transporter 22 165 2.5E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_16385 0389c3229041d5a3f9fd317728789485 81 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 4 74 1.8E-31 T 11-10-2018 IPR019242 Protein of unknown function DUF2198 UP12_15395 a6587ea53101dff68882c8554456f45c 261 Gene3D G3DSA:3.40.50.300 5 250 3.8E-55 T 11-10-2018 UP12_15395 a6587ea53101dff68882c8554456f45c 261 SMART SM00382 30 225 1.7E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_15395 a6587ea53101dff68882c8554456f45c 261 Pfam PF00005 ABC transporter 21 173 3.9E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_15395 a6587ea53101dff68882c8554456f45c 261 SUPERFAMILY SSF52540 6 233 3.99E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_15395 a6587ea53101dff68882c8554456f45c 261 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 UP12_15395 a6587ea53101dff68882c8554456f45c 261 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 6 246 3.8E-113 T 11-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 UP12_18405 5a002f0cb9b2321091d06edc2985b6b0 606 Gene3D G3DSA:3.40.50.1110 426 599 9.3E-14 T 11-10-2018 IPR036514 SGNH hydrolase superfamily UP12_18405 5a002f0cb9b2321091d06edc2985b6b0 606 SUPERFAMILY SSF52266 436 596 1.3E-16 T 11-10-2018 UP12_18405 5a002f0cb9b2321091d06edc2985b6b0 606 Pfam PF01757 Acyltransferase family 13 341 1.7E-22 T 11-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UP12_02770 f1cc2ece6fcf08f2e504337de5dece18 322 Gene3D G3DSA:3.10.450.540 220 322 6.5E-15 T 11-10-2018 UP12_02770 f1cc2ece6fcf08f2e504337de5dece18 322 Pfam PF12642 Conjugative transposon protein TcpC 91 317 3.4E-51 T 11-10-2018 IPR024735 Conjugative transposon protein TcpC UP12_15355 ce80a8f6c09d4955fc57396a83a94092 403 Pfam PF01420 Type I restriction modification DNA specificity domain 220 391 2.1E-17 T 11-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 UP12_15355 ce80a8f6c09d4955fc57396a83a94092 403 Pfam PF01420 Type I restriction modification DNA specificity domain 19 190 8.8E-10 T 11-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 UP12_15355 ce80a8f6c09d4955fc57396a83a94092 403 SUPERFAMILY SSF116734 208 402 1.34E-37 T 11-10-2018 UP12_15355 ce80a8f6c09d4955fc57396a83a94092 403 Gene3D G3DSA:3.90.220.20 215 402 5.2E-31 T 11-10-2018 UP12_15355 ce80a8f6c09d4955fc57396a83a94092 403 Gene3D G3DSA:3.90.220.20 16 203 1.1E-27 T 11-10-2018 UP12_15355 ce80a8f6c09d4955fc57396a83a94092 403 SUPERFAMILY SSF116734 13 204 2.13E-30 T 11-10-2018 UP12_16910 b831e19a3f2ff433679b04b8bee9593c 305 Pfam PF13407 Periplasmic binding protein domain 40 290 3.1E-66 T 11-10-2018 IPR025997 Periplasmic binding protein UP12_16910 b831e19a3f2ff433679b04b8bee9593c 305 Gene3D G3DSA:3.40.50.2300 43 290 1.3E-91 T 11-10-2018 UP12_16910 b831e19a3f2ff433679b04b8bee9593c 305 Gene3D G3DSA:3.40.50.2300 138 271 1.3E-91 T 11-10-2018 UP12_16910 b831e19a3f2ff433679b04b8bee9593c 305 SUPERFAMILY SSF53822 32 301 4.57E-88 T 11-10-2018 IPR028082 Periplasmic binding protein-like I UP12_17570 db44391f4f04242c8ad680c00e56eff0 226 SUPERFAMILY SSF89562 20 181 3.66E-46 T 11-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily UP12_17570 db44391f4f04242c8ad680c00e56eff0 226 Pfam PF03737 Aldolase/RraA 26 171 3.3E-42 T 11-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein UP12_17570 db44391f4f04242c8ad680c00e56eff0 226 Gene3D G3DSA:3.50.30.100 1 193 1.1E-58 T 11-10-2018 UP12_18700 e9561358e3dd08c4142510c496a8013c 411 Pfam PF02342 TerD domain 1 168 2.3E-19 T 11-10-2018 IPR003325 TerD domain UP12_18700 e9561358e3dd08c4142510c496a8013c 411 Gene3D G3DSA:2.60.60.30 17 167 7.3E-22 T 11-10-2018 UP12_04725 b31f0352106eecb19047fc461f5857f0 214 Pfam PF07875 Coat F domain 118 179 7.5E-15 T 11-10-2018 IPR012851 Spore coat protein CotF-like UP12_04750 7d961380746d8936677c1b94c48c0fe3 116 Pfam PF17326 Family of unknown function (DUF5365) 1 112 2.6E-31 T 11-10-2018 IPR020355 Uncharacterised protein family YhcU UP12_04750 7d961380746d8936677c1b94c48c0fe3 116 ProDom PD081567 YHCU 1 108 5.0E-17 T 11-10-2018 IPR020355 Uncharacterised protein family YhcU UP12_17130 f552030d5bcd3bb2d110f50034bf9f93 421 SUPERFAMILY SSF103473 4 406 2.49E-60 T 11-10-2018 IPR036259 MFS transporter superfamily UP12_17130 f552030d5bcd3bb2d110f50034bf9f93 421 Pfam PF07690 Major Facilitator Superfamily 23 365 2.1E-40 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 UP12_17130 f552030d5bcd3bb2d110f50034bf9f93 421 Gene3D G3DSA:1.20.1250.20 1 408 2.7E-54 T 11-10-2018 UP12_14610 589c27e0116a51d253aad229b45af165 165 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 7 92 4.4E-10 T 11-10-2018 IPR010064 Bacteriophage HK97-gp10, putative tail-component UP12_14610 589c27e0116a51d253aad229b45af165 165 ProDom PD034535 XKDI PHAGE PHAGE-LIKE PBSX LIN1275 RELATED ELEMENT YQBI 1 159 3.0E-44 T 11-10-2018 UP12_03320 3cf9807e0b324a30ae865ad84bc6d841 266 ProDom PD113106 YVBI TRANSMEMBRANE MEMBRANE YEBC YBEC 66 254 6.0E-25 T 11-10-2018 UP12_02375 3b1d325dead8bc9baf5dd07ec05879e9 422 Gene3D G3DSA:3.90.550.10 40 263 1.0E-47 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_02375 3b1d325dead8bc9baf5dd07ec05879e9 422 Pfam PF13641 Glycosyltransferase like family 2 49 279 8.2E-34 T 11-10-2018 UP12_02375 3b1d325dead8bc9baf5dd07ec05879e9 422 SUPERFAMILY SSF53448 44 317 3.62E-63 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases UP12_10290 fb29b64a6bd728a6c3d1e7680725a826 225 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 33.924 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 UP12_10290 fb29b64a6bd728a6c3d1e7680725a826 225 Pfam PF02224 Cytidylate kinase 7 219 1.6E-81 T 11-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 UP12_10290 fb29b64a6bd728a6c3d1e7680725a826 225 Gene3D G3DSA:3.40.50.300 1 224 5.5E-87 T 11-10-2018 UP12_10290 fb29b64a6bd728a6c3d1e7680725a826 225 SUPERFAMILY SSF52540 6 219 2.28E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_10290 fb29b64a6bd728a6c3d1e7680725a826 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 218 3.7E-90 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 UP12_02425 13579107fc64a1aa14ae93e3f1d9f45f 86 Pfam PF04226 Transglycosylase associated protein 34 79 1.8E-8 T 11-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 UP12_06255 9398e34ae14e0e26bc9125f4b7049693 441 Gene3D G3DSA:1.20.1740.10 7 441 1.4E-93 T 11-10-2018 UP12_06255 9398e34ae14e0e26bc9125f4b7049693 441 Pfam PF13520 Amino acid permease 12 408 3.3E-55 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_06255 9398e34ae14e0e26bc9125f4b7049693 441 PIRSF PIRSF006060 1 441 1.3E-81 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_15970 fba8e38030c12972dcc8795a35ce18e4 441 TIGRFAM TIGR00797 matE: MATE efflux family protein 12 406 2.3E-68 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_15970 fba8e38030c12972dcc8795a35ce18e4 441 Pfam PF01554 MatE 12 172 1.9E-16 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_15970 fba8e38030c12972dcc8795a35ce18e4 441 Pfam PF01554 MatE 255 392 2.3E-15 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 UP12_11160 cd014d59d5f6f00521fcffb2fab88c95 127 Pfam PF14173 ComG operon protein 7 30 124 4.7E-21 T 11-10-2018 IPR020372 Competence operon G protein 7, ComGG UP12_17545 545b20fe9d8ac4e834a936cca9bbf7b7 92 ProDom PD063106 YXIC 1 90 2.0E-17 T 11-10-2018 IPR020315 Uncharacterised protein family YxiC UP12_17545 545b20fe9d8ac4e834a936cca9bbf7b7 92 Pfam PF17279 Family of unknown function (DUF5344) 2 88 3.6E-24 T 11-10-2018 UP12_15700 3bd9798124d8c4c9c6342f6872dd2f77 203 Pfam PF03458 UPF0126 domain 92 161 2.2E-18 T 11-10-2018 IPR005115 Uncharacterised domain UPF0126 UP12_15700 3bd9798124d8c4c9c6342f6872dd2f77 203 Pfam PF03458 UPF0126 domain 5 78 8.3E-19 T 11-10-2018 IPR005115 Uncharacterised domain UPF0126 UP12_17100 b3a4ebf330be85dafe542ccf74c30448 140 ProDom PD031895 YWNG MEMBRANE TRANSMEMBRANE YWNC 9 102 7.0E-12 T 11-10-2018 IPR035287 Protein of unknown function DUF5362 UP12_17100 b3a4ebf330be85dafe542ccf74c30448 140 Pfam PF17319 Family of unknown function (DUF5362) 12 107 1.9E-6 T 11-10-2018 IPR035287 Protein of unknown function DUF5362 UP12_12355 e1a49eaabed58dc95f63c2b183daea9c 276 Pfam PF01578 Cytochrome C assembly protein 67 270 2.4E-35 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 UP12_02415 4af5eb2d1365fcba7ded554a1e09337c 189 Gene3D G3DSA:3.40.630.30 2 174 3.5E-51 T 11-10-2018 UP12_02415 4af5eb2d1365fcba7ded554a1e09337c 189 Pfam PF13302 Acetyltransferase (GNAT) domain 11 148 1.3E-24 T 11-10-2018 IPR000182 GNAT domain UP12_02415 4af5eb2d1365fcba7ded554a1e09337c 189 SUPERFAMILY SSF55729 2 173 1.12E-47 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase UP12_10630 e04b82bff013032bfd0c5b86f51f1436 122 SUPERFAMILY SSF46785 24 117 1.74E-25 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily UP12_10630 e04b82bff013032bfd0c5b86f51f1436 122 Pfam PF01638 HxlR-like helix-turn-helix 31 119 4.9E-25 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type UP12_10630 e04b82bff013032bfd0c5b86f51f1436 122 Gene3D G3DSA:1.10.10.10 19 122 6.9E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily UP12_06765 21c7ce10d2868908296ea6dcf2540383 179 Pfam PF06271 RDD family 19 172 1.9E-25 T 11-10-2018 IPR010432 RDD UP12_13470 bb81121fb50bfad092241864b8aa7292 148 TIGRFAM TIGR03646 YtoQ_fam: YtoQ family protein 3 146 3.9E-70 T 11-10-2018 IPR019884 YtoQ family protein UP12_13470 bb81121fb50bfad092241864b8aa7292 148 Pfam PF11071 Nucleoside 2-deoxyribosyltransferase YtoQ 6 145 4.9E-66 T 11-10-2018 IPR019884 YtoQ family protein UP12_13470 bb81121fb50bfad092241864b8aa7292 148 Gene3D G3DSA:3.40.50.450 2 148 2.5E-5 T 11-10-2018 UP12_11035 3768f81ad738a589b451f88465d5f573 68 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 61 1.1E-15 T 11-10-2018 IPR025664 Stage III sporulation protein AC/AD family UP12_11035 3768f81ad738a589b451f88465d5f573 68 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 2.7E-32 T 11-10-2018 IPR009570 Stage III sporulation protein AC UP12_13750 1fcb681d30a88dc6d34831c8fe7d2eaf 80 Gene3D G3DSA:2.40.240.20 1 77 3.4E-34 T 11-10-2018 UP12_13750 1fcb681d30a88dc6d34831c8fe7d2eaf 80 Pfam PF10763 Protein of unknown function (DUF2584) 1 80 6.0E-39 T 11-10-2018 IPR019699 Protein of unknown function DUF2584 UP12_13750 1fcb681d30a88dc6d34831c8fe7d2eaf 80 SUPERFAMILY SSF88697 1 80 1.59E-31 T 11-10-2018 IPR015947 PUA-like superfamily UP12_00285 2cd4d47dd17beb9453ba99364680d734 85 Pfam PF06257 Biofilm formation stimulator VEG 4 74 3.5E-31 T 11-10-2018 IPR009366 Protein Veg GO:0006355 UP12_00285 2cd4d47dd17beb9453ba99364680d734 85 PIRSF PIRSF037257 1 84 9.6E-37 T 11-10-2018 IPR009366 Protein Veg GO:0006355 UP12_00285 2cd4d47dd17beb9453ba99364680d734 85 Gene3D G3DSA:2.30.30.100 1 78 2.0E-25 T 11-10-2018 UP12_04650 235f2608ef22f1e92d506b3a2f07ed35 300 Pfam PF12671 Putative amidase domain 137 289 1.3E-40 T 11-10-2018 IPR024301 Putative amidase domain UP12_01945 6817940f263a2edd18b4a5be892d9080 268 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 33 262 4.0E-76 T 11-10-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 UP12_01945 6817940f263a2edd18b4a5be892d9080 268 SUPERFAMILY SSF110710 1 263 5.23E-91 T 11-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like UP12_02380 e9206a0fe24a456a0b551983d9d04ec1 695 Gene3D G3DSA:2.60.120.260 331 471 1.1E-15 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily UP12_02380 e9206a0fe24a456a0b551983d9d04ec1 695 Gene3D G3DSA:2.60.120.260 39 172 1.5E-15 T 11-10-2018 IPR008979 Galactose-binding-like domain superfamily UP12_02380 e9206a0fe24a456a0b551983d9d04ec1 695 Pfam PF03170 Bacterial cellulose synthase subunit 56 581 2.7E-37 T 11-10-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 UP12_01720 4ca7c3b2984ea23f92b00f15bb517c11 540 Pfam PF02652 L-lactate permease 14 535 1.4E-193 T 11-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 UP12_01720 4ca7c3b2984ea23f92b00f15bb517c11 540 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 4 537 1.7E-193 T 11-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 UP12_17695 5b41e252f573dc189e7a19e6f33c0545 180 Pfam PF09671 Spore coat protein (Spore_GerQ) 93 168 2.2E-40 T 11-10-2018 IPR014099 Spore coat protein GerQ UP12_17695 5b41e252f573dc189e7a19e6f33c0545 180 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 91 172 1.6E-45 T 11-10-2018 IPR014099 Spore coat protein GerQ UP12_17695 5b41e252f573dc189e7a19e6f33c0545 180 PIRSF PIRSF038931 14 180 3.6E-51 T 11-10-2018 IPR014099 Spore coat protein GerQ UP12_18970 9c4aba4e235935db954939bfe459504a 293 SUPERFAMILY SSF53474 20 278 2.7E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_18970 9c4aba4e235935db954939bfe459504a 293 Pfam PF00756 Putative esterase 34 261 3.2E-19 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 UP12_18970 9c4aba4e235935db954939bfe459504a 293 Gene3D G3DSA:3.40.50.1820 24 285 1.1E-67 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_12630 1af0ebeac11dde03c29111270cab026c 135 Gene3D G3DSA:1.20.5.320 41 102 4.5E-5 T 11-10-2018 UP12_12630 1af0ebeac11dde03c29111270cab026c 135 Pfam PF01391 Collagen triple helix repeat (20 copies) 43 76 4.7E-7 T 11-10-2018 IPR008160 Collagen triple helix repeat UP12_09225 2bc773710de446406f2b601d6eeb9b0e 200 Pfam PF09335 SNARE associated Golgi protein 29 154 3.0E-24 T 11-10-2018 IPR032816 SNARE associated Golgi protein UP12_08860 71d0d7e036c99e9a2d3adf636988bff4 195 SUPERFAMILY SSF46689 8 69 2.05E-15 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_08860 71d0d7e036c99e9a2d3adf636988bff4 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 61 5.0E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_08860 71d0d7e036c99e9a2d3adf636988bff4 195 Gene3D G3DSA:1.10.357.10 5 192 6.2E-36 T 11-10-2018 UP12_03675 e08e41cba2ddc947c387b799a46a2da0 215 Pfam PF13021 Domain of unknown function (DUF3885) 171 208 8.4E-19 T 11-10-2018 IPR024976 Domain of unknown function DUF3885 UP12_08385 27ff05f70a5d195fab4d9caf3cdd0a24 249 Pfam PF05908 Poly-gamma-glutamate hydrolase 52 236 4.5E-71 T 11-10-2018 IPR008585 Poly-gamma-glutamate hydrolase UP12_08385 27ff05f70a5d195fab4d9caf3cdd0a24 249 Gene3D G3DSA:3.40.630.100 46 248 4.0E-63 T 11-10-2018 IPR038128 Poly-gamma-glutamate hydrolase superfamily UP12_11185 797d156605cfba11f7f3ab2166655b06 346 Gene3D G3DSA:1.20.81.30 4 112 7.1E-15 T 11-10-2018 UP12_11185 797d156605cfba11f7f3ab2166655b06 346 Pfam PF00482 Type II secretion system (T2SS), protein F 20 137 2.3E-12 T 11-10-2018 IPR018076 Type II secretion system F domain UP12_11185 797d156605cfba11f7f3ab2166655b06 346 Pfam PF00482 Type II secretion system (T2SS), protein F 216 338 3.8E-19 T 11-10-2018 IPR018076 Type II secretion system F domain UP12_11185 797d156605cfba11f7f3ab2166655b06 346 Gene3D G3DSA:1.20.81.30 199 311 2.1E-14 T 11-10-2018 UP12_11185 797d156605cfba11f7f3ab2166655b06 346 PRINTS PR00812 Bacterial general secretion pathway protein F signature 327 346 1.0E-6 T 11-10-2018 IPR003004 GspF/PilC family UP12_11185 797d156605cfba11f7f3ab2166655b06 346 PRINTS PR00812 Bacterial general secretion pathway protein F signature 13 25 1.0E-6 T 11-10-2018 IPR003004 GspF/PilC family UP12_11185 797d156605cfba11f7f3ab2166655b06 346 PRINTS PR00812 Bacterial general secretion pathway protein F signature 109 137 1.0E-6 T 11-10-2018 IPR003004 GspF/PilC family UP12_09990 a68c0ecfd09e4e86b8cee39ba8e207cc 78 Pfam PF17522 Family of unknown function (DUF5446) 2 69 7.2E-26 T 11-10-2018 IPR020252 Protein of unknown function DUF5446 UP12_02470 fe9c2a8ff32f01b488cd81ff5ebb3fda 255 Pfam PF12730 ABC-2 family transporter protein 4 183 3.7E-20 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 UP12_07285 4a40b3cd5b41f764a9cc65d6491ad63b 402 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 8 359 7.5E-124 T 11-10-2018 IPR014226 Sporulation integral membrane protein YlbJ UP12_07285 4a40b3cd5b41f764a9cc65d6491ad63b 402 Pfam PF07670 Nucleoside recognition 42 138 2.5E-6 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 UP12_16940 834a1b62685bfd88947f8325a5526a69 196 Pfam PF02417 Chromate transporter 9 172 2.3E-34 T 11-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 UP12_18835 eba0d90a18269cb0e938b916ccf34786 275 Pfam PF02361 Cobalt transport protein 13 232 2.5E-29 T 11-10-2018 IPR003339 ABC/ECF transporter, transmembrane component UP12_02700 d2f2c909af61185dc91821dc600a62aa 468 Gene3D G3DSA:3.40.50.300 205 451 1.5E-35 T 11-10-2018 UP12_02700 d2f2c909af61185dc91821dc600a62aa 468 SUPERFAMILY SSF52540 216 389 1.72E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_02700 d2f2c909af61185dc91821dc600a62aa 468 Pfam PF01580 FtsK/SpoIIIE family 220 367 7.1E-7 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 UP12_16710 6a2c7e78a5ca121a46289bad98848d6d 275 Pfam PF01061 ABC-2 type transporter 18 233 1.0E-26 T 11-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 UP12_02050 a1f76360a14ebd1f0b703a0a3409d269 214 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 10 210 1.1E-6 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT UP12_17970 ccb4a61936589d128ba3f4361a39089e 363 Gene3D G3DSA:3.20.10.10 171 339 1.9E-137 T 11-10-2018 UP12_17970 ccb4a61936589d128ba3f4361a39089e 363 Gene3D G3DSA:3.30.470.10 25 352 1.9E-137 T 11-10-2018 UP12_17970 ccb4a61936589d128ba3f4361a39089e 363 SUPERFAMILY SSF56752 5 353 2.62E-118 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 UP12_17970 ccb4a61936589d128ba3f4361a39089e 363 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 44 356 4.3E-125 T 11-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 UP12_17970 ccb4a61936589d128ba3f4361a39089e 363 PIRSF PIRSF006468 2 358 4.1E-134 T 11-10-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 UP12_17970 ccb4a61936589d128ba3f4361a39089e 363 Pfam PF01063 Amino-transferase class IV 70 312 3.1E-37 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 UP12_17970 ccb4a61936589d128ba3f4361a39089e 363 ProSitePatterns PS00770 Aminotransferases class-IV signature. 233 262 - T 11-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 UP12_10430 51b77c757da7df51894fd220a2a31d5d 195 Pfam PF07670 Nucleoside recognition 43 150 2.3E-10 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 UP12_01470 8c46894798d348ae1ec1194a09fac930 195 Pfam PF08006 Protein of unknown function (DUF1700) 1 181 1.4E-21 T 11-10-2018 IPR012963 Protein of unknown function DUF1700 UP12_08920 565ac6c2844fb0f8df41db58e0c23e6d 189 SUPERFAMILY SSF46689 8 71 1.39E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 UP12_08920 565ac6c2844fb0f8df41db58e0c23e6d 189 Gene3D G3DSA:1.10.357.10 5 182 5.3E-33 T 11-10-2018 UP12_08920 565ac6c2844fb0f8df41db58e0c23e6d 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 61 1.4E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 UP12_13155 cb008d5a6f2ff29fa33de86f0d1fada4 100 Pfam PF14007 YtpI-like protein 5 90 4.1E-35 T 11-10-2018 IPR025618 YtpI-like protein UP12_19255 a695087acb21df860f6e25b9507020f3 120 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 15 120 8.0E-14 T 11-10-2018 UP12_18645 26bdcb270ed6f0912fbd6e9023f83e3e 162 Pfam PF13826 Domain of unknown function (DUF4188) 18 135 1.0E-46 T 11-10-2018 IPR025444 Monooxygenase af470-like UP12_12180 b094f8f647b6b222002f8cbde45e00c3 210 Pfam PF01810 LysE type translocator 13 201 6.7E-29 T 11-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UP12_11905 654983950c081f467c796c5f0b136729 67 Pfam PF10750 Protein of unknown function (DUF2536) 1 66 3.3E-34 T 11-10-2018 IPR019686 Protein of unknown function DUF2536 UP12_06435 00564604172e3227dd20124e67b6257f 229 Gene3D G3DSA:3.10.450.40 160 228 1.2E-11 T 11-10-2018 UP12_06435 00564604172e3227dd20124e67b6257f 229 Pfam PF03413 Peptidase propeptide and YPEB domain 167 224 5.3E-12 T 11-10-2018 IPR025711 PepSY domain UP12_17475 c33909338627043812996d8fadaaf75e 220 Pfam PF02163 Peptidase family M50 127 188 6.2E-9 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 UP12_19235 6a242d347401204fb5d2f5247b69c0ff 123 ProDom PD295888 PLASMID MEMBRANE TRANSMEMBRANE PXO2-26/BXB0024/GBAA_PXO2_0024 10 106 1.0E-8 T 11-10-2018 IPR020334 Uncharacterised protein family, plasmid pXO2-26 UP12_08525 d3c35b5a0d2b498be9a06b226d050e4d 124 Pfam PF14112 Immunity protein 22 7 124 1.4E-26 T 11-10-2018 IPR025560 Immunity protein 22 UP12_02815 c543df38c2fe8f2b933b24c356e8c959 621 Pfam PF14280 Domain of unknown function (DUF4365) 54 163 1.1E-6 T 11-10-2018 IPR025375 Domain of unknown function DUF4365 UP12_02900 59ac964ac58cfe13355a76b7f9cef94e 89 Gene3D G3DSA:3.10.450.130 18 85 6.7E-8 T 11-10-2018 UP12_10165 07e4aab9510405885ba137f8446fab4c 219 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 214 31.566 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 UP12_10165 07e4aab9510405885ba137f8446fab4c 219 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 208 8.8E-45 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 UP12_10165 07e4aab9510405885ba137f8446fab4c 219 Gene3D G3DSA:3.20.20.70 3 213 3.2E-51 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_10165 07e4aab9510405885ba137f8446fab4c 219 SUPERFAMILY SSF51366 4 210 8.16E-43 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 UP12_02480 383f574372b2a08f8e2cb107f1105e91 106 Pfam PF00085 Thioredoxin 5 101 2.2E-18 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 UP12_02480 383f574372b2a08f8e2cb107f1105e91 106 Gene3D G3DSA:3.40.30.10 1 105 5.9E-25 T 11-10-2018 UP12_02480 383f574372b2a08f8e2cb107f1105e91 106 SUPERFAMILY SSF52833 3 104 5.84E-26 T 11-10-2018 IPR036249 Thioredoxin-like superfamily UP12_18335 620b0320b1c6d3fcbbc8082738468abf 123 Pfam PF06993 Protein of unknown function (DUF1304) 11 119 9.5E-42 T 11-10-2018 IPR009732 Protein of unknown function DUF1304 UP12_09795 47edb1d0081e7af92058ee9d801c3d0a 205 Pfam PF14005 YpjP-like protein 71 202 9.0E-61 T 11-10-2018 IPR025616 YpjP-like protein UP12_06170 4f1b27866fb5584a960ccbb34ed5d40f 332 Pfam PF01384 Phosphate transporter family 22 320 5.6E-90 T 11-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 UP12_03825 00c2c40549d2b0a872e7f3c5d5602b98 115 Pfam PF11181 Heat induced stress protein YflT 5 104 3.4E-31 T 11-10-2018 IPR025889 General stress protein 17M-like domain UP12_02885 3955c74edf4ee7b55e61f8254b5465f9 300 Pfam PF07859 alpha/beta hydrolase fold 68 273 9.8E-66 T 11-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 UP12_02885 3955c74edf4ee7b55e61f8254b5465f9 300 SUPERFAMILY SSF53474 30 296 1.77E-62 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_02885 3955c74edf4ee7b55e61f8254b5465f9 300 Gene3D G3DSA:3.40.50.1820 4 297 1.5E-79 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_04720 2b8794c1b712f8db4af7757590d98fb2 291 SUPERFAMILY SSF55486 147 281 9.89E-5 T 11-10-2018 UP12_05855 0665743b92f1d5168988c2c022202b8f 147 Pfam PF10612 Spore coat protein Z 3 139 3.1E-35 T 11-10-2018 IPR019593 Spore coat protein Z/Y UP12_13025 d065b378035726fdbc0c79cc839bad25 152 Pfam PF03477 ATP cone domain 50 136 8.5E-18 T 11-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 UP12_13025 d065b378035726fdbc0c79cc839bad25 152 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 4.8E-74 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 UP12_13025 d065b378035726fdbc0c79cc839bad25 152 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 152 84.251 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 UP12_18450 f0eb57427c19f2aa9ecf8d1341ec3910 445 Pfam PF00324 Amino acid permease 18 419 9.0E-86 T 11-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 UP12_18450 f0eb57427c19f2aa9ecf8d1341ec3910 445 Gene3D G3DSA:1.20.1740.10 9 445 2.1E-50 T 11-10-2018 UP12_18450 f0eb57427c19f2aa9ecf8d1341ec3910 445 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 11-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 UP12_18450 f0eb57427c19f2aa9ecf8d1341ec3910 445 PIRSF PIRSF006060 1 445 1.8E-68 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 UP12_01700 b03775131fff505d6a733acfe44157d6 240 SUPERFAMILY SSF51735 2 190 9.84E-34 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_01700 b03775131fff505d6a733acfe44157d6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01700 b03775131fff505d6a733acfe44157d6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01700 b03775131fff505d6a733acfe44157d6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01700 b03775131fff505d6a733acfe44157d6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01700 b03775131fff505d6a733acfe44157d6 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.5E-13 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01700 b03775131fff505d6a733acfe44157d6 240 Pfam PF00106 short chain dehydrogenase 4 187 1.3E-30 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR UP12_01700 b03775131fff505d6a733acfe44157d6 240 Gene3D G3DSA:3.40.50.720 1 199 8.6E-35 T 11-10-2018 UP12_17705 349409cc351cfa791602f14766384ca8 123 Pfam PF04241 Protein of unknown function (DUF423) 18 105 9.0E-32 T 11-10-2018 IPR006696 Protein of unknown function DUF423 UP12_10125 8e608da2a49f1fe7c3c215f6180196ab 148 Pfam PF10673 Protein of unknown function (DUF2487) 9 145 1.5E-45 T 11-10-2018 IPR019615 Protein of unknown function DUF2487 UP12_05780 d33b464c9d8f83563e102dac9841a0fc 121 Hamap MF_01861 UPF0738 protein . 3 121 29.345 T 11-10-2018 IPR020908 Uncharacterised protein family UPF0738 UP12_14125 e45aba6d8ed6e167453057d0cef265ca 842 SUPERFAMILY SSF52540 286 473 1.74E-5 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_14190 9a3e5f17802820062a762f80dce5c554 365 SUPERFAMILY SSF69279 19 150 4.08E-8 T 11-10-2018 UP12_03950 ac1458cf67689e3f40d53d70baa5f194 128 Pfam PF09350 Domain of unknown function (DUF1992) 8 73 1.6E-21 T 11-10-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain UP12_12185 e0abcde4e68bcd827c4fb04438cc4f49 205 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 16 193 3.3E-23 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like UP12_09775 02087fa7dd88b5b0aad1f82706741493 207 SUPERFAMILY SSF69593 33 206 1.57E-7 T 11-10-2018 UP12_18805 1c4c9549b5d88b5739dda14b54b61033 588 Gene3D G3DSA:3.40.50.300 5 316 6.7E-9 T 11-10-2018 UP12_18805 1c4c9549b5d88b5739dda14b54b61033 588 Pfam PF10088 Uncharacterised protein conserved in bacteria (DUF2326) 453 587 6.1E-27 T 11-10-2018 IPR018760 Protein of unknown function DUF2326 UP12_13455 051391f046abefb5eab9d3c3792f84e4 267 PIRSF PIRSF012562 1 266 5.7E-133 T 11-10-2018 IPR010838 Protein of unknown unction DUF1444 UP12_13455 051391f046abefb5eab9d3c3792f84e4 267 Hamap MF_01548 UPF0354 protein . 1 266 47.088 T 11-10-2018 IPR010838 Protein of unknown unction DUF1444 UP12_13455 051391f046abefb5eab9d3c3792f84e4 267 Pfam PF07285 Protein of unknown function (DUF1444) 1 265 6.2E-131 T 11-10-2018 IPR010838 Protein of unknown unction DUF1444 UP12_05615 ef1c21c1e59f8ace17a966b0ab7e883d 246 SUPERFAMILY SSF53474 53 244 1.82E-9 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_05615 ef1c21c1e59f8ace17a966b0ab7e883d 246 Gene3D G3DSA:3.40.50.1820 18 242 4.1E-8 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_13220 46fce054a63b42b2364f00f2c147755c 173 Pfam PF06271 RDD family 33 156 6.2E-22 T 11-10-2018 IPR010432 RDD UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 Pfam PF02040 Arsenical pump membrane protein 6 428 3.8E-204 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 6 429 6.8E-206 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 147 171 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_01915 0fca148f7555deb839fe2dd90a64ace3 432 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 3.8E-102 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 UP12_11805 a4533f849a7a6d374b1ac06f8b4049f8 262 Pfam PF00905 Penicillin binding protein transpeptidase domain 59 244 4.5E-33 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 UP12_11805 a4533f849a7a6d374b1ac06f8b4049f8 262 SUPERFAMILY SSF56601 41 250 6.18E-33 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like UP12_11805 a4533f849a7a6d374b1ac06f8b4049f8 262 ProSitePatterns PS00337 Beta-lactamase class-D active site. 70 80 - T 11-10-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 UP12_11805 a4533f849a7a6d374b1ac06f8b4049f8 262 Gene3D G3DSA:3.40.710.10 29 260 4.2E-92 T 11-10-2018 UP12_12905 191b272eca397fe1cc2b32d05d24a80d 88 SUPERFAMILY SSF102829 13 87 4.45E-20 T 11-10-2018 IPR036192 Cell division protein ZapA-like superfamily UP12_12905 191b272eca397fe1cc2b32d05d24a80d 88 Pfam PF05164 Cell division protein ZapA 13 85 1.7E-16 T 11-10-2018 IPR007838 Cell division protein ZapA-like UP12_16015 da77c75c18defb94d9edc4cec6ca82c4 504 Pfam PF01943 Polysaccharide biosynthesis protein 8 290 1.7E-14 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 UP12_14175 dea72f10ff3dfac0693599987cb9404c 348 Pfam PF04865 Baseplate J-like protein 62 306 2.3E-62 T 11-10-2018 IPR006949 Baseplate protein J-like UP12_17910 3e93e756982ac284db88ef39fb87f2f8 226 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 1 223 5.8E-88 T 11-10-2018 IPR005261 Conserved hypothetical protein CHP00659 UP12_17910 3e93e756982ac284db88ef39fb87f2f8 226 Pfam PF04172 LrgB-like family 11 223 6.1E-75 T 11-10-2018 IPR007300 CidB/LrgB family UP12_14545 7df5c74bc47838041c1e425561f2ce59 127 Pfam PF12571 Phage tail-collar fibre protein 5 113 2.3E-8 T 11-10-2018 IPR022225 Phage tail fibre protein UP12_11345 1d88a78226c18703431fde23e9f71c0d 100 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 22 98 7.0E-15 T 11-10-2018 IPR020506 Uncharacterised protein family YqfZ UP12_19350 78acdc17d55ea94151d9fa0bd29885a1 190 Pfam PF14163 Super-infection exclusion protein B 17 159 2.4E-30 T 11-10-2018 IPR025982 Superinfection exclusion protein B UP12_18070 e39b39a1ed9b1a3ae4e09cd0ef76b0bf 337 SUPERFAMILY SSF81345 10 333 1.44E-85 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_18070 e39b39a1ed9b1a3ae4e09cd0ef76b0bf 337 Pfam PF01032 FecCD transport family 27 333 3.1E-98 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 UP12_18070 e39b39a1ed9b1a3ae4e09cd0ef76b0bf 337 Gene3D G3DSA:1.10.3470.10 13 336 4.2E-101 T 11-10-2018 IPR037294 ABC transporter, BtuC-like UP12_01960 e732e66f032fa4d552c834eb958c390e 142 Pfam PF14040 Deoxyribonuclease NucA/NucB 46 129 6.2E-12 T 11-10-2018 IPR029476 Deoxyribonuclease NucA/NucB UP12_07200 c2c28c3d5b9465e44d405aa230955aaa 307 Pfam PF02628 Cytochrome oxidase assembly protein 8 287 7.3E-32 T 11-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 UP12_07200 c2c28c3d5b9465e44d405aa230955aaa 307 Hamap MF_01664 Heme A synthase [ctaA]. 1 303 28.316 T 11-10-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 UP12_08720 6a6f7adecf47fdb14704c958426f0fb8 235 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 214 1.7E-67 T 11-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 UP12_09280 42a5e502c7edcafc0c5c9418eeb41def 107 Gene3D G3DSA:2.102.10.10 3 107 8.5E-24 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UP12_09280 42a5e502c7edcafc0c5c9418eeb41def 107 Pfam PF00355 Rieske [2Fe-2S] domain 10 92 2.0E-12 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 UP12_09280 42a5e502c7edcafc0c5c9418eeb41def 107 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 7 104 4.7E-27 T 11-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 UP12_09280 42a5e502c7edcafc0c5c9418eeb41def 107 SUPERFAMILY SSF50022 8 106 3.54E-28 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 UP12_05115 24bdf852706cdc28eb4b52bb295cdd2b 246 Pfam PF00005 ABC transporter 19 162 5.5E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 UP12_05115 24bdf852706cdc28eb4b52bb295cdd2b 246 SUPERFAMILY SSF52540 3 232 4.47E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase UP12_05115 24bdf852706cdc28eb4b52bb295cdd2b 246 SMART SM00382 28 231 2.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain UP12_05115 24bdf852706cdc28eb4b52bb295cdd2b 246 Gene3D G3DSA:3.40.50.300 1 245 6.9E-63 T 11-10-2018 UP12_08455 03dccb0d442f8f339d1d45d151f82a44 130 SUPERFAMILY SSF52218 2 121 5.67E-20 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08455 03dccb0d442f8f339d1d45d151f82a44 130 PIRSF PIRSF005087 1 126 1.3E-36 T 11-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI UP12_08455 03dccb0d442f8f339d1d45d151f82a44 130 TIGRFAM TIGR00333 nrdI: nrdI protein 4 123 1.6E-42 T 11-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI UP12_08455 03dccb0d442f8f339d1d45d151f82a44 130 Gene3D G3DSA:3.40.50.360 1 130 7.0E-42 T 11-10-2018 IPR029039 Flavoprotein-like superfamily UP12_08455 03dccb0d442f8f339d1d45d151f82a44 130 Hamap MF_00128 Protein NrdI [nrdI]. 2 122 25.641 T 11-10-2018 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial UP12_08455 03dccb0d442f8f339d1d45d151f82a44 130 Pfam PF07972 NrdI Flavodoxin like 4 112 6.0E-30 T 11-10-2018 IPR004465 Ribonucleotide reductase Class Ib, NrdI UP12_10585 acd9b72fa162f0cb175385678c168054 75 Pfam PF14004 Protein of unknown function (DUF4227) 6 75 9.4E-33 T 11-10-2018 IPR025321 Protein of unknown function DUF4227 UP12_06780 9e65e42e29955475c83a6ce3f3d91fe5 153 Pfam PF14177 YkyB-like protein 13 149 6.8E-69 T 11-10-2018 IPR025552 YkyB-like protein UP12_05120 0c003226a33f9caef94ce5a22e8b9202 406 PIRSF PIRSF037259 4 406 9.6E-128 T 11-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 UP12_05120 0c003226a33f9caef94ce5a22e8b9202 406 Pfam PF05975 Bacterial ABC transporter protein EcsB 7 386 3.2E-126 T 11-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 UP12_05385 6efb15bebc87dc136a23a207b88aab11 301 Gene3D G3DSA:3.90.850.10 87 301 3.2E-82 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UP12_05385 6efb15bebc87dc136a23a207b88aab11 301 SUPERFAMILY SSF56529 83 300 3.27E-72 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 UP12_05385 6efb15bebc87dc136a23a207b88aab11 301 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 93 300 1.1E-67 T 11-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 UP12_15115 9322fffac7ce10beea15e635e15471f4 106 Pfam PF14068 Putative membrane protein 7 106 1.1E-41 T 11-10-2018 IPR025917 Putative membrane protein YuiB UP12_04335 ff24042bbbdf7eb527c14815fd86fdc0 140 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 13 122 4.0E-16 T 11-10-2018 UP12_04335 ff24042bbbdf7eb527c14815fd86fdc0 140 Pfam PF14184 Regulatory protein YrvL 7 130 2.5E-34 T 11-10-2018 IPR025912 Regulatory protein YrvL UP12_06860 4ab03b4bed87b47653cb8c9c1a7ccc58 297 Gene3D G3DSA:2.130.10.10 2 153 1.0E-6 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 UP12_06860 4ab03b4bed87b47653cb8c9c1a7ccc58 297 SUPERFAMILY SSF110296 7 282 4.71E-19 T 11-10-2018 UP12_10515 666bdd52f2a888561d90410d7bf1b34f 490 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 19 476 2.8E-155 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_10515 666bdd52f2a888561d90410d7bf1b34f 490 PIRSF PIRSF005690 3 489 2.9E-142 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 UP12_00190 b395ac30d64868ff01b7ad57e513be24 204 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 9 198 5.3E-60 T 11-10-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein UP12_01620 895af99b7f4ab42c51d11710a8aaac17 346 Pfam PF01757 Acyltransferase family 6 316 3.2E-26 T 11-10-2018 IPR002656 Acyltransferase 3 GO:0016747 UP12_19560 214ced0e497fea2b1a42da45165185df 291 SUPERFAMILY SSF53335 85 215 2.11E-8 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase UP12_19560 214ced0e497fea2b1a42da45165185df 291 Gene3D G3DSA:3.40.50.150 75 282 6.7E-8 T 11-10-2018 UP12_07710 daa282df494867c27f09936861c39c83 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 6.9E-36 T 11-10-2018 IPR005531 Alkaline shock protein Asp23 UP12_15110 b6cee703b36690fcfa57070b4170da64 214 SUPERFAMILY SSF50685 120 161 8.02E-8 T 11-10-2018 IPR036908 RlpA-like domain superfamily UP12_15110 b6cee703b36690fcfa57070b4170da64 214 Pfam PF06725 3D domain 120 181 4.8E-18 T 11-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 UP12_00375 c12fc7bc690ac1ba533ca0ac4f5b62db 124 Pfam PF04977 Septum formation initiator 45 119 9.4E-18 T 11-10-2018 IPR007060 Septum formation initiator FtsL/DivIC UP12_11230 7874d8add8c9b46e770f429d1e4fa493 104 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 101 1.5E-36 T 11-10-2018 IPR002767 Thiamine-binding protein UP12_11230 7874d8add8c9b46e770f429d1e4fa493 104 Gene3D G3DSA:3.30.70.930 1 104 1.6E-38 T 11-10-2018 IPR029756 MTH1187/YkoF-like UP12_11230 7874d8add8c9b46e770f429d1e4fa493 104 SUPERFAMILY SSF89957 1 103 1.96E-31 T 11-10-2018 IPR029756 MTH1187/YkoF-like UP12_11230 7874d8add8c9b46e770f429d1e4fa493 104 Pfam PF01910 Thiamine-binding protein 4 98 4.6E-34 T 11-10-2018 IPR002767 Thiamine-binding protein UP12_18125 7448c363922fa832b7058449be10771b 253 Gene3D G3DSA:3.40.50.10990 62 220 7.7E-54 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UP12_18125 7448c363922fa832b7058449be10771b 253 Pfam PF00925 GTP cyclohydrolase II 72 218 3.5E-47 T 11-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UP12_18125 7448c363922fa832b7058449be10771b 253 SUPERFAMILY SSF142695 72 220 1.7E-46 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 UP12_15020 7f3f327b2ae4857c35924fb4f2e848a1 367 Pfam PF01594 AI-2E family transporter 18 348 3.6E-89 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like UP12_00150 45105ede4a9c3f178a0f9a4b5ad18b29 74 Pfam PF10704 Protein of unknown function (DUF2508) 4 69 2.5E-24 T 11-10-2018 IPR019644 Protein of unknown function DUF2508 UP12_06140 e0b369e014b62a95cc75969366c0568e 123 Pfam PF17428 Family of unknown function (DUF5412) 3 117 2.9E-41 T 11-10-2018 IPR035406 Protein of unknown function DUF5412 UP12_15430 41b9d1b32fcbd7a865ae255f14734c70 114 SUPERFAMILY SSF110455 4 112 3.79E-33 T 11-10-2018 UP12_15430 41b9d1b32fcbd7a865ae255f14734c70 114 Gene3D G3DSA:3.40.1360.20 2 114 4.5E-42 T 11-10-2018 UP12_15430 41b9d1b32fcbd7a865ae255f14734c70 114 SMART SM00493 6 80 7.1E-6 T 11-10-2018 IPR006171 TOPRIM domain UP12_16365 9709e52959d6392b6a62bc59ca94db60 111 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 7 108 4.0E-20 T 11-10-2018 UP12_05600 2cda4f821ef26567f6ffedf2c0fd9ce8 59 Pfam PF14168 YjzC-like protein 1 55 2.4E-27 T 11-10-2018 IPR025549 YjzC-like protein UP12_16640 166120dbc46bacf571502ba9c71e10e3 485 Pfam PF04932 O-Antigen ligase 262 410 9.1E-14 T 11-10-2018 IPR007016 O-antigen ligase-related UP12_03930 f43e257426306a8179a0378bd7427929 195 Pfam PF14172 Domain of unknown function (DUF4309) 47 190 2.3E-33 T 11-10-2018 IPR025453 Protein of unknown function DUF4309 UP12_04120 ae38fa8824bcc78fd44e263f002fadd6 394 Pfam PF08874 Domain of unknown function (DUF1835) 2 124 4.5E-34 T 11-10-2018 IPR014973 Protein of unknown function DUF1835 UP12_04120 ae38fa8824bcc78fd44e263f002fadd6 394 Pfam PF12395 Protein of unknown function 161 272 1.4E-29 T 11-10-2018 IPR022123 Protein of unknown function DUF3658 UP12_15095 574d74477fec80755104b4401e06775c 442 Pfam PF13726 Na+-H+ antiporter family 2 88 1.2E-31 T 11-10-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal UP12_15095 574d74477fec80755104b4401e06775c 442 Pfam PF03553 Na+/H+ antiporter family 150 436 1.2E-70 T 11-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 UP12_07965 0d2d91544b00d53dcad6c1790a024386 219 Pfam PF04347 Flagellar biosynthesis protein, FliO 94 180 5.6E-12 T 11-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 UP12_00635 c6cdfa438750eb6b8c136fe949b7aa5b 170 Pfam PF05991 YacP-like NYN domain 4 166 5.6E-57 T 11-10-2018 IPR010298 Protein of unknown function DUF901 UP12_12110 7d3fd64afe85d5ed98c3e81b3e96600d 98 Pfam PF13797 Post-transcriptional regulator 8 87 4.7E-30 T 11-10-2018 IPR025716 Post-transcriptional regulator UP12_14490 f6294c4c7c86bfaf755b2b5024da26b5 167 Pfam PF06114 IrrE N-terminal-like domain 49 151 6.2E-16 T 11-10-2018 IPR010359 IrrE N-terminal-like domain UP12_15225 819a138f64780567307d1d6e3f0260f8 211 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 12 177 1.1E-28 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like UP12_05280 6f578613b79c827d0eefef88948571d4 205 Pfam PF09335 SNARE associated Golgi protein 41 159 1.9E-23 T 11-10-2018 IPR032816 SNARE associated Golgi protein UP12_02780 fca97a98529468ae9e7d7d6525543419 155 Pfam PF12648 TcpE family 7 112 5.3E-26 T 11-10-2018 IPR025608 TcpE family UP12_02780 fca97a98529468ae9e7d7d6525543419 155 Pfam PF03125 C. elegans Sre G protein-coupled chemoreceptor 29 114 8.4E-5 T 11-10-2018 IPR004151 7TM GPCR, serpentine receptor class e (Sre) GO:0007606|GO:0016021 UP12_16285 f3a3bc80e597683901e2978b90f0a1a1 262 Pfam PF13529 Peptidase_C39 like family 73 234 3.6E-36 T 11-10-2018 IPR039564 Peptidase C39-like UP12_16285 f3a3bc80e597683901e2978b90f0a1a1 262 Gene3D G3DSA:3.90.70.10 68 262 2.4E-64 T 11-10-2018 UP12_16285 f3a3bc80e597683901e2978b90f0a1a1 262 PIRSF PIRSF032442 9 262 3.6E-73 T 11-10-2018 IPR016997 Uncharacterised conserved protein UCP032442 UP12_16455 1f2de1b6da0ea097e16620163ce42bee 246 Pfam PF01925 Sulfite exporter TauE/SafE 4 242 4.8E-41 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 UP12_01340 32154e57219f0619d9f7443eb23f4e08 153 Pfam PF04463 Protein of unknown function (DUF523) 2 146 4.9E-43 T 11-10-2018 IPR007553 Domain of unknown function DUF523 UP12_05620 9b17ce0353c21ee9bd06b7a0485a28b5 191 ProDom PD032558 YJAV MED CDS GENES ARGF 1 126 3.0E-17 T 11-10-2018 UP12_01150 f6845891f1050fd4e194fb71dc8e7b3b 473 TIGRFAM TIGR04405 SkfF: sporulation killing factor system integral membrane protein 1 470 3.0E-192 T 11-10-2018 IPR030920 Sporulation killing factor system integral membrane protein SkfF UP12_03500 728fd12b819a0f3ce3ec633faddf3267 326 Pfam PF13529 Peptidase_C39 like family 81 136 6.3E-7 T 11-10-2018 IPR039564 Peptidase C39-like UP12_04955 fbb394e4da67c85f77b548b1f23f6dce 205 Gene3D G3DSA:3.40.50.720 1 205 2.5E-35 T 11-10-2018 UP12_04955 fbb394e4da67c85f77b548b1f23f6dce 205 Pfam PF13460 NAD(P)H-binding 7 193 9.4E-33 T 11-10-2018 IPR016040 NAD(P)-binding domain UP12_04955 fbb394e4da67c85f77b548b1f23f6dce 205 SUPERFAMILY SSF51735 1 203 6.23E-24 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily UP12_05610 20436796426c78ecd358439ca307b33f 64 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 1.7E-20 T 11-10-2018 IPR021324 Protein of unknown function DUF2929 UP12_01310 b0c4bd3917f4d8a55b6ed8cc830f96b1 258 Pfam PF01925 Sulfite exporter TauE/SafE 9 252 2.2E-39 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 UP12_05070 ab261a336856a041d33779571e729f3e 29 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 3 28 3.0E-12 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_05070 ab261a336856a041d33779571e729f3e 29 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 28 3.7E-11 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like UP12_16020 1cfd91e635644f2a4af3c78cca4cc162 340 Pfam PF04230 Polysaccharide pyruvyl transferase 50 291 2.7E-25 T 11-10-2018 IPR007345 Polysaccharide pyruvyl transferase UP12_16575 76dec614e6cff867d7ce87f9158d9b84 139 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 2 138 2.9E-57 T 11-10-2018 IPR022258 Flagellar operon protein YvyF UP12_09890 59fc10664018ddf8639345c3b4bf8763 87 Pfam PF10752 Protein of unknown function (DUF2533) 2 84 1.3E-39 T 11-10-2018 IPR019688 Protein of unknown function DUF2533 UP12_14750 6db0b887125870527939c1038969971b 343 SUPERFAMILY SSF51412 4 340 1.18E-60 T 11-10-2018 UP12_14750 6db0b887125870527939c1038969971b 343 Pfam PF03060 Nitronate monooxygenase 5 341 1.7E-99 T 11-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 UP12_14750 6db0b887125870527939c1038969971b 343 Gene3D G3DSA:3.20.20.70 2 343 2.8E-112 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 UP12_13500 f0af253b666ead47ecac9e0717b46f5d 91 Pfam PF14165 YtzH-like protein 3 88 6.3E-36 T 11-10-2018 IPR025547 YtzH-like protein UP12_12480 b2f026d36d9dc256b27ca12ba08ed65d 129 Pfam PF15594 Immunity protein 50 9 124 1.4E-30 T 11-10-2018 IPR028957 Immunity protein 50 UP12_08765 77af972bd0721de4a444c7d28833e65c 80 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 80 28.973 T 11-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like UP12_08765 77af972bd0721de4a444c7d28833e65c 80 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 8 74 1.1E-25 T 11-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like UP12_17540 a7049694fe7e68eafb7fdd5a1d71cb51 509 Pfam PF14449 Pre-toxin TG 329 393 7.0E-21 T 11-10-2018 IPR027797 Pre-toxin TG domain UP12_17540 a7049694fe7e68eafb7fdd5a1d71cb51 509 Pfam PF04740 LXG domain of WXG superfamily 2 202 3.1E-61 T 11-10-2018 IPR006829 LXG domain UP12_11940 507f9a54979c5bd368ea9969e36b9450 309 Pfam PF01136 Peptidase family U32 77 306 1.6E-63 T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 UP12_11515 c56b054ebbe491b70a9b974ae0ed948e 330 Hamap MF_01562 UPF0365 protein . 3 323 50.121 T 11-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity UP12_11515 c56b054ebbe491b70a9b974ae0ed948e 330 Pfam PF12127 SigmaW regulon antibacterial 9 319 3.1E-165 T 11-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity UP12_07945 226e35133bb551c900a3662d976172c0 142 Pfam PF03748 Flagellar basal body-associated protein FliL 49 142 1.9E-16 T 11-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 UP12_09980 48f17a619acbda79d51d720228d7ac21 150 Pfam PF14179 YppG-like protein 55 148 2.3E-26 T 11-10-2018 IPR025555 YppG-like protein UP12_09855 3515a8202a5262a1e8233b5508f7642e 60 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 60 1.0E-20 T 11-10-2018 UP12_15010 afcac30f6c5e305a2c8a560498ceaddd 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 1.0E-27 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF UP12_16030 a6359c33a779d8bda4934429d358193f 367 Pfam PF14897 EpsG family 36 362 2.4E-50 T 11-10-2018 UP12_14905 b5d50f73233b509d2199f23fcb5c2ee8 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 295 6.1E-38 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 UP12_08035 a37690b7e3de1683dfee1985ccca789f 179 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 1 178 2.0E-27 T 11-10-2018 UP12_14765 ac28e1216d6c8451081ef4a47515a35f 224 Pfam PF04298 Putative neutral zinc metallopeptidase 4 218 2.1E-88 T 11-10-2018 IPR007395 Putative neutral zinc metallopeptidase UP12_00025 dd04baacc4cd23643f2f1dce4acc481b 81 Pfam PF04025 Domain of unknown function (DUF370) 3 72 1.1E-13 T 11-10-2018 IPR007169 Extracellular matrix regulatory protein A UP12_11175 2c4e65fd22ea42dd22fcdde4bbd724c7 148 PIRSF PIRSF021292 5 148 4.0E-31 T 11-10-2018 IPR016785 ComG operon protein 4 GO:0030420 UP12_11175 2c4e65fd22ea42dd22fcdde4bbd724c7 148 SUPERFAMILY SSF54523 11 113 2.43E-7 T 11-10-2018 UP12_00195 a38a97353a941a317bb29a8203658358 348 Pfam PF05816 Toxic anion resistance protein (TelA) 37 346 3.5E-52 T 11-10-2018 IPR008863 Toxic anion resistance UP12_11390 3a447fe1a37aab8e6c997ecd9fa6ab76 84 ProDom PD060869 YQFT IG BH1387 1 68 1.0E-22 T 11-10-2018 IPR020277 Protein of unknown function DUF2624 UP12_11390 3a447fe1a37aab8e6c997ecd9fa6ab76 84 Pfam PF11116 Protein of unknown function (DUF2624) 2 83 5.5E-33 T 11-10-2018 IPR020277 Protein of unknown function DUF2624 UP12_14925 7f312eb3012e4e285276e594345cfff1 143 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 11 134 1.1E-34 T 11-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein UP12_14925 7f312eb3012e4e285276e594345cfff1 143 TIGRFAM TIGR00943 2a6301s02: monovalent cation:proton antiporter 29 135 1.5E-43 T 11-10-2018 IPR005281 Monovalent cation:proton antiporter, subunit B GO:0006812|GO:0008324|GO:0016021 UP12_03430 03ed8f5183e07dbf7a346e66b9160e63 73 Pfam PF11127 Protein of unknown function (DUF2892) 1 70 1.2E-13 T 11-10-2018 IPR021309 Protein of unknown function DUF2892 UP12_15015 adef0f6ec22e0885bc47c144f5577f7a 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 9.3E-26 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF UP12_03170 378557ca8834f16e95ce5ead11dbde5a 207 SUPERFAMILY SSF55811 5 154 4.72E-18 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 UP12_03170 378557ca8834f16e95ce5ead11dbde5a 207 Gene3D G3DSA:3.90.79.10 1 181 1.4E-33 T 11-10-2018 UP12_03170 378557ca8834f16e95ce5ead11dbde5a 207 Pfam PF00293 NUDIX domain 49 154 6.9E-7 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 UP12_18725 5c70dca67642d8d0a51c141631685265 196 Pfam PF15600 Immunity protein 64 5 183 3.7E-18 T 11-10-2018 IPR028951 Immunity protein 64 UP12_04320 1ad74e9a6da652263f076b3a5c90f9c0 862 Pfam PF09586 Bacterial membrane protein YfhO 12 840 9.9E-202 T 11-10-2018 IPR018580 Uncharacterised protein family YfhO UP12_09395 9156170386959029939fb601e900163d 543 Pfam PF14158 YndJ-like protein 30 281 5.7E-79 T 11-10-2018 IPR025450 YndJ-like protein UP12_13465 7ca80539ffa627847f1476e8c22ba070 342 Pfam PF13303 Phosphotransferase system, EIIC 18 331 4.7E-99 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 UP12_03985 0cd196c29325ec721fe08c48cea16f74 71 Hamap MF_00829 UPF0435 protein . 4 71 18.881 T 11-10-2018 IPR009507 Protein of unknown function UPF0435 UP12_03985 0cd196c29325ec721fe08c48cea16f74 71 Pfam PF06569 Protein of unknown function (DUF1128) 1 71 9.7E-32 T 11-10-2018 IPR009507 Protein of unknown function UPF0435 UP12_10425 7722d056db1d9d444970f1ef7fae0309 178 Pfam PF07670 Nucleoside recognition 46 146 5.0E-7 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 UP12_01060 db1a4897b582895c5aa8e50779615efe 208 Gene3D G3DSA:1.10.10.1320 8 94 1.4E-6 T 11-10-2018 UP12_01060 db1a4897b582895c5aa8e50779615efe 208 Pfam PF13490 Putative zinc-finger 3 38 1.1E-8 T 11-10-2018 IPR027383 Putative zinc-finger UP12_16725 d602edd5ac91a5fdd2469026432f3f69 488 Pfam PF09318 Glycosyl transferase 1 domain A 34 218 5.1E-27 T 11-10-2018 IPR015397 Glycosyl transferase 1, domain A UP12_00185 7547bb0fec99162f7c3c7432a260bb6e 63 Pfam PF10764 Inhibitor of sigma-G Gin 10 54 1.4E-18 T 11-10-2018 IPR019700 Anti-sigma-G factor Gin UP12_03445 437598c4c214fad074e2730f85a67cf0 169 Pfam PF13079 Protein of unknown function (DUF3916) 18 167 3.6E-47 T 11-10-2018 IPR025075 Protein of unknown function DUF3916 UP12_11170 320b383be260cc5b387daf4ee2de08c0 105 ProDom PD073895 COMPETENCE COMGE LATE MACHINERY MEMBRANE OPERON DNA THE METHYLATION PART 1 99 2.0E-8 T 11-10-2018 IPR020488 Competence operon G, ComGE UP12_03030 5b9d0cbde2f0691465e006c9a867ed5a 195 Pfam PF01810 LysE type translocator 13 190 1.1E-14 T 11-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 UP12_08590 f933c5558da4c708cb42f72a5e89b395 147 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 87 142 1.0E-16 T 11-10-2018 IPR018691 Protein of unknown function DUF2188 UP12_10995 9ecedf03cf9c6187e23983b124632bab 135 Pfam PF03780 Asp23 family, cell envelope-related function 16 121 2.3E-36 T 11-10-2018 IPR005531 Alkaline shock protein Asp23 UP12_11015 a6522a067199e147e5105d46de815779 223 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 28 217 5.6E-69 T 11-10-2018 IPR014195 Sporulation stage III, protein AG UP12_11440 878ff0c561f6281028b10db1a33396de 166 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 16 161 28.923 T 11-10-2018 IPR003791 Protein of unknown function UPF0178 UP12_11440 878ff0c561f6281028b10db1a33396de 166 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 31 159 5.8E-39 T 11-10-2018 IPR003791 Protein of unknown function UPF0178 UP12_11135 9c0efe0b784c59d54b747b3bef9a6e4e 266 Pfam PF12389 Camelysin metallo-endopeptidase 4 239 7.2E-35 T 11-10-2018 IPR022121 Peptidase M73, camelysin UP12_11135 9c0efe0b784c59d54b747b3bef9a6e4e 266 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 44 4.1E-10 T 11-10-2018 IPR023833 Signal peptide, camelysin UP12_03405 afa53a0ba40fa0acf51e4e32b50b2aab 552 Gene3D G3DSA:1.10.10.2840 411 543 2.8E-22 T 11-10-2018 UP12_03405 afa53a0ba40fa0acf51e4e32b50b2aab 552 Pfam PF07905 Purine catabolism regulatory protein-like family 7 126 9.0E-28 T 11-10-2018 IPR012914 Purine catabolism PurC-like domain UP12_03405 afa53a0ba40fa0acf51e4e32b50b2aab 552 Pfam PF13556 PucR C-terminal helix-turn-helix domain 480 537 9.2E-21 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain UP12_01345 a65b49dc05830fa56344e3709d625106 138 Pfam PF17225 Domain of unknown function (DUF5300) 36 105 4.3E-8 T 11-10-2018 IPR033782 Domain of unknown function DUF5301 UP12_19115 dbcf0753e56a50cfdb0f61f9c96ad532 439 SUPERFAMILY SSF53474 117 186 6.47E-7 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold UP12_14185 2b89884d842efd9a1c1af285409d1e5b 93 Pfam PF10844 Protein of unknown function (DUF2577) 7 57 1.5E-7 T 11-10-2018 IPR022555 Protein of unknown function, DUF2577 UP12_14185 2b89884d842efd9a1c1af285409d1e5b 93 ProDom PD028957 PBSX RELATED XKDR ELEMENT LIN1285 PHAGE PHAGE-LIKE YQBR 3 88 7.0E-19 T 11-10-2018 IPR022555 Protein of unknown function, DUF2577 UP12_06160 eddcbe51f99d5dd8d6cdbd305ddba3d1 56 Gene3D G3DSA:1.20.5.740 34 56 4.0E-12 T 11-10-2018 UP12_06160 eddcbe51f99d5dd8d6cdbd305ddba3d1 56 Pfam PF14185 Antitoxin SpoIISB, type II toxin-antitoxin system 1 56 1.6E-36 T 11-10-2018 IPR025897 Antitoxin SpoIISB UP12_19275 b446c7a0f8ece08132db77e04cf7b186 101 Pfam PF16943 Cag pathogenicity island, type IV secretory system 18 99 2.1E-11 T 11-10-2018 IPR031607 Cag pathogenicity island, type IV secretory system UP12_09605 330ef4fb0f20bf9384af7f7e212ebd9b 67 Pfam PF11755 Protein of unknown function (DUF3311) 10 62 7.2E-18 T 11-10-2018 IPR021741 Protein of unknown function DUF3311 UP12_15560 d6a3e1d778a76f1a786fd419de0d2b0d 221 Pfam PF04012 PspA/IM30 family 1 210 1.5E-51 T 11-10-2018 IPR007157 PspA/IM30 UP12_13135 6e30d57cb46cf4fe3f3305d7d5a09beb 113 Pfam PF14034 Sporulation protein YtrH 10 108 2.0E-42 T 11-10-2018 IPR025689 Sporulation protein YtrH UP12_15870 0f88d3fcfd77647e71ce6913e3794bf0 210 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 201 1.1E-74 T 11-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 UP12_15870 0f88d3fcfd77647e71ce6913e3794bf0 210 Pfam PF01914 MarC family integral membrane protein 3 205 6.6E-70 T 11-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 UP12_07150 f2ab79828de73641a33a89aabf1471f6 93 Pfam PF14036 YlaH-like protein 7 82 1.2E-30 T 11-10-2018 IPR025620 YlaH-like protein UP12_12365 b1d18f1ed180856c1e2917be55fee89e 161 ProDom PD104119 YSXD OB2071 ORFY 1 161 2.0E-33 T 11-10-2018 UP12_14930 9d31f4cdf2d04f0b10d486026529b491 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 9.8E-30 T 11-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like UP12_09400 e84a1c050c5bb570f774dce6f640a979 201 Pfam PF13761 Domain of unknown function (DUF4166) 14 193 4.3E-53 T 11-10-2018 IPR025311 Domain of unknown function DUF4166 UP12_07700 4486ee7e2cdfb6b30d2abb7818d94cce 26 Pfam PF08183 Stage V sporulation protein family 1 25 9.3E-18 T 11-10-2018 IPR012609 Sporulation stage V, protein M UP12_10640 ffdd64761504bd908e319c20198623b6 73 Pfam PF13025 Protein of unknown function (DUF3886) 4 70 2.8E-17 T 11-10-2018 IPR024980 Protein of unknown function DUF3886 UP12_17285 164ffabb62f911e70b6cdb5a6b8ed98d 318 Pfam PF03547 Membrane transport protein 165 314 8.4E-22 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UP12_17285 164ffabb62f911e70b6cdb5a6b8ed98d 318 Pfam PF03547 Membrane transport protein 7 158 2.2E-23 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 UP12_08220 20877795073747d72b08329a68f89bfd 78 Pfam PF14035 YlzJ-like protein 3 64 2.4E-22 T 11-10-2018 IPR025619 YlzJ-like protein UP12_14630 f5b9bead0a86ac6d00342e5323057851 362 Pfam PF14550 Putative phage serine protease XkdF 41 155 2.6E-44 T 11-10-2018 IPR027924 Phage-like element PBSX protein, XkdF UP12_02755 73eca5dede2a0899d93fbf422c4b4688 271 ProDom PD304634 PLASMID TRANSMEMBRANE PXO2-23/BXB0022/GBAA_PXO2_0022 MEMBRANE 13 269 9.0E-53 T 11-10-2018 IPR020397 Uncharacterised protein family, plasmid pXO2-23 UP12_11590 5932e4bced46df09ba6519e00273cff9 402 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 183 386 1.1E-71 T 11-10-2018 IPR010897 Sporulation stage II, protein P UP12_11590 5932e4bced46df09ba6519e00273cff9 402 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 104 382 1.1E-74 T 11-10-2018 IPR010897 Sporulation stage II, protein P UP12_05355 aa321c5d4dded38f1caabc0e240b3fb2 204 Pfam PF10737 Spore germination protein GerPC 22 195 4.2E-64 T 11-10-2018 IPR019673 Spore germination protein GerPC UP12_16315 103da7b688205f5b0667fd759ed6da34 314 Pfam PF07670 Nucleoside recognition 17 100 2.8E-9 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 UP12_16315 103da7b688205f5b0667fd759ed6da34 314 Pfam PF07670 Nucleoside recognition 177 264 1.7E-7 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 UP12_01770 536463fff361bf8076fb006dcf34fa8a 198 Pfam PF09347 Domain of unknown function (DUF1989) 7 172 1.7E-52 T 11-10-2018 IPR018959 Protein of unknown function DUF1989 UP12_05055 a53909fc97ba250784d711cf589a112d 76 Pfam PF14147 Sporulation protein YhaL 4 55 3.0E-28 T 11-10-2018 IPR025428 Sporulation protein YhaL UP12_10690 357cb9d8c90993277432635de71a119b 114 Pfam PF08863 YolD-like protein 20 111 4.2E-21 T 11-10-2018 IPR014962 YolD-like protein UP12_03260 3826ef8a6ec421b999106cb5cb918c8a 396 Pfam PF01882 Protein of unknown function DUF58 204 277 3.6E-20 T 11-10-2018 IPR002881 Domain of unknown function DUF58 UP12_03855 cf6e7454deb5fca9e7c1fba412a41fdb 688 TIGRFAM TIGR03721 exospore_TM: BclB C-terminal domain 518 687 3.8E-60 T 11-10-2018 IPR021210 Exosporium BclB, C-terminal UP12_18595 e0e623302b4e9a86f6d2457abbd54520 775 Pfam PF02687 FtsX-like permease family 285 365 6.6E-8 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 UP12_14870 1511e9b56f100eac85f44020775b0f6f 136 Pfam PF04134 Protein of unknown function, DUF393 10 119 1.0E-34 T 11-10-2018 IPR007263 Protein of unknown function DUF393 UP12_08470 08e83c418b340f2a672febcab755fcd1 205 Gene3D G3DSA:3.90.79.10 1 205 2.3E-60 T 11-10-2018 UP12_18545 f72baf9f6ddb251a179f5d05a096c9fb 142 Pfam PF13273 Protein of unknown function (DUF4064) 3 106 7.7E-17 T 11-10-2018 IPR025273 Domain of unknown function DUF4064 UP12_12145 c2ac98ea007c63b8043412609d251470 66 Pfam PF11146 Protein of unknown function (DUF2905) 6 62 3.9E-20 T 11-10-2018 IPR021320 Protein of unknown function DUF2905 UP12_17880 51f6482c28fe9a0847951d2702e1b283 112 Pfam PF14119 Domain of unknown function (DUF4288) 5 90 2.6E-22 T 11-10-2018 IPR025630 Protein of unknown function DUF4288 UP12_06490 afaa3c2b8ccb37df363767d93ed5552d 204 Pfam PF09335 SNARE associated Golgi protein 32 157 1.2E-21 T 11-10-2018 IPR032816 SNARE associated Golgi protein UP12_02510 8c5881b3c45119709e39d7d650e13c27 159 Pfam PF03703 Bacterial PH domain 73 148 6.7E-17 T 11-10-2018 IPR005182 Domain of unknown function DUF304