locus-tag	class	description
HZ310_00020	COG4720	Psort location CytoplasmicMembrane, score
HZ310_00030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HZ310_00040	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HZ310_00070	COG0640	Transcriptional regulator
HZ310_00075	COG2814	Major facilitator Superfamily
HZ310_00085	COG2409	Drug exporters of the RND superfamily
HZ310_00095	COG3850	Histidine kinase
HZ310_00095	COG5002	protein histidine kinase activity
HZ310_00110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZ310_00130	COG0583	DNA-binding transcription factor activity
HZ310_00135	COG0384	phenazine biosynthesis protein PhzF
HZ310_00150	COG2188	Transcriptional regulator
HZ310_00155	COG2723	6-phospho-beta-galactosidase activity
HZ310_00160	COG2814	Major facilitator Superfamily
HZ310_00170	COG2814	Major facilitator Superfamily
HZ310_00180	COG1113	amino acid transport
HZ310_00220	COG2190	(PTS) system
HZ310_00220	COG1263	PTS System
HZ310_00220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_00225	COG2723	6-phospho-beta-galactosidase activity
HZ310_00230	COG3711	transcriptional antiterminator
HZ310_00235	COG0457	Tetratricopeptide repeat
HZ310_00245	COG1136	(ABC) transporter
HZ310_00255	COG2814	Major facilitator Superfamily
HZ310_00260	COG1309	transcriptional regulator
HZ310_00265	COG3835	regulator
HZ310_00270	COG2610	gluconate transmembrane transporter activity
HZ310_00275	COG1929	Belongs to the glycerate kinase type-1 family
HZ310_00280	COG2824	Alkylphosphonate utilization operon protein PhnA
HZ310_00285	COG1131	(ABC) transporter
HZ310_00290	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HZ310_00300	COG2851	Citrate transporter
HZ310_00305	COG1874	Beta-galactosidase
HZ310_00315	COG3833	ABC-type maltose transport systems, permease component
HZ310_00320	COG1175	transmembrane transport
HZ310_00325	COG2182	Extracellular solute-binding protein
HZ310_00330	COG1609	Transcriptional regulator
HZ310_00335	COG0583	DNA-binding transcription factor activity
HZ310_00365	COG1957	nucleoside hydrolase
HZ310_00370	COG1737	Transcriptional regulator
HZ310_00375	COG1070	Carbohydrate kinase
HZ310_00385	COG4335	DNA alkylation repair
HZ310_00390	COG1113	amino acid transport
HZ310_00395	COG0840	transmembrane signaling receptor activity
HZ310_00400	COG0673	inositol 2-dehydrogenase activity
HZ310_00405	COG0789	Transcriptional regulator
HZ310_00410	COG0561	phosphatase activity
HZ310_00435	COG0477	Major facilitator Superfamily
HZ310_00440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HZ310_00440	COG2755	lipolytic protein G-D-S-L family
HZ310_00450	COG2390	Transcriptional regulator
HZ310_00455	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HZ310_00460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HZ310_00465	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
HZ310_00470	COG1846	Transcriptional regulator
HZ310_00475	COG0778	Nitroreductase
HZ310_00480	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HZ310_00515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HZ310_00520	COG4721	ABC-type cobalt transport system, permease component
HZ310_00525	COG1122	ATPase activity
HZ310_00530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HZ310_00540	COG3878	Protein conserved in bacteria
HZ310_00545	COG3711	transcriptional antiterminator
HZ310_00550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_00550	COG2190	(PTS) system
HZ310_00550	COG1263	PTS System
HZ310_00555	COG2723	6-phospho-beta-galactosidase activity
HZ310_00560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HZ310_00565	COG2610	gluconate transmembrane transporter activity
HZ310_00575	COG2084	Dehydrogenase
HZ310_00580	COG1737	Transcriptional regulator
HZ310_00595	COG2195	Cleaves the N-terminal amino acid of tripeptides
HZ310_00600	COG4842	Belongs to the WXG100 family
HZ310_00625	COG1396	sequence-specific DNA binding
HZ310_00630	COG0252	asparaginase activity
HZ310_00635	COG1027	Aspartate ammonia-lyase
HZ310_00640	COG1757	Na H antiporter
HZ310_00665	COG3711	transcriptional antiterminator
HZ310_00665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_00670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZ310_00680	COG2723	6-phospho-beta-galactosidase activity
HZ310_00685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZ310_00690	COG1447	Phosphotransferase system cellobiose-specific component IIA
HZ310_00695	COG0726	polysaccharide deacetylase
HZ310_00700	COG0346	lactoylglutathione lyase activity
HZ310_00705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZ310_00705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZ310_00710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZ310_00710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZ310_00715	COG2514	catechol 2,3-dioxygenase activity
HZ310_00720	COG1733	regulation of RNA biosynthetic process
HZ310_00725	COG5386	Cell surface protein
HZ310_00730	COG5386	Cell surface protein
HZ310_00755	COG4509	Sortase family
HZ310_00775	COG1271	oxidase subunit
HZ310_00780	COG1294	oxidase, subunit
HZ310_00785	COG4988	ABC transporter
HZ310_00790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HZ310_00800	COG1595	DNA-templated transcription, initiation
HZ310_00815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HZ310_00830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_00830	COG3711	transcriptional antiterminator
HZ310_00835	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZ310_00840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZ310_00845	COG1447	Phosphotransferase system cellobiose-specific component IIA
HZ310_00850	COG1486	melibiose metabolic process
HZ310_00860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HZ310_00865	COG3420	alginic acid biosynthetic process
HZ310_00875	COG1129	ABC transporter
HZ310_00880	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZ310_00885	COG2357	RelA SpoT domain protein
HZ310_00895	COG0457	Tetratricopeptide repeat
HZ310_00900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_00905	COG0765	amino acid transport
HZ310_00915	COG0346	lactoylglutathione lyase activity
HZ310_00920	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HZ310_00925	COG1346	cytolysis
HZ310_00935	COG0583	DNA-binding transcription factor activity
HZ310_00940	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HZ310_00945	COG0352	thiamine-phosphate diphosphorylase activity
HZ310_00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HZ310_00975	COG3162	membrane
HZ310_00995	COG2246	polysaccharide biosynthetic process
HZ310_01010	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HZ310_01015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HZ310_01020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HZ310_01030	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HZ310_01035	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HZ310_01040	COG1845	cytochrome c oxidase, subunit III
HZ310_01045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HZ310_01055	COG0772	Belongs to the SEDS family
HZ310_01060	COG0778	Nitroreductase
HZ310_01065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZ310_01070	COG1404	Belongs to the peptidase S8 family
HZ310_01080	COG3711	transcriptional antiterminator
HZ310_01085	COG1263	PTS System
HZ310_01085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_01090	COG1621	beta-fructofuranosidase activity
HZ310_01105	COG0351	phosphomethylpyrimidine kinase
HZ310_01115	COG1216	Glycosyl transferase, family 2
HZ310_01120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HZ310_01125	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_01135	COG2233	PERMEase
HZ310_01140	COG2363	Small membrane protein
HZ310_01160	COG0463	Glycosyl transferase, family 2
HZ310_01165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HZ310_01170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZ310_01175	COG0456	acetyltransferase
HZ310_01180	COG2089	acid synthase
HZ310_01185	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
HZ310_01190	COG3980	spore coat polysaccharide biosynthesis protein
HZ310_01195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HZ310_01200	COG1088	dTDP-glucose 4,6-dehydratase activity
HZ310_01205	COG1091	dTDP-4-dehydrorhamnose reductase activity
HZ310_01210	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HZ310_01215	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_01220	COG0436	Aminotransferase
HZ310_01225	COG0151	Belongs to the GarS family
HZ310_01230	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_01235	COG1917	Cupin 2, conserved barrel domain protein
HZ310_01240	COG0077	Prephenate dehydratase
HZ310_01245	COG2814	Major facilitator Superfamily
HZ310_01250	COG1522	sequence-specific DNA binding
HZ310_01270	COG0280	phosphate acetyltransferase
HZ310_01280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HZ310_01310	COG5444	nuclease activity
HZ310_01350	COG4844	belongs to the
HZ310_01355	COG1078	dGTPase activity
HZ310_01360	COG3465	dGTPase activity
HZ310_01385	COG1131	(ABC) transporter
HZ310_01390	COG1942	4-Oxalocrotonate Tautomerase
HZ310_01395	COG1994	Peptidase M50
HZ310_01405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HZ310_01410	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HZ310_01415	COG0010	Belongs to the arginase family
HZ310_01425	COG4506	Protein conserved in bacteria
HZ310_01430	COG0018	arginyl-trna synthetase
HZ310_01440	COG1619	proteins homologs of microcin C7 resistance protein MccF
HZ310_01445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HZ310_01450	COG1132	(ABC) transporter
HZ310_01455	COG1619	proteins homologs of microcin C7 resistance protein MccF
HZ310_01465	COG4294	response to UV
HZ310_01470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HZ310_01475	COG0247	lactate metabolic process
HZ310_01475	COG2181	nitrate reductase activity
HZ310_01480	COG0183	Belongs to the thiolase family
HZ310_01485	COG1250	3-hydroxyacyl-CoA dehydrogenase
HZ310_01490	COG1960	acyl-CoA dehydrogenase activity
HZ310_01495	COG1960	acyl-CoA dehydrogenase activity
HZ310_01530	COG3343	RNA polymerase activity
HZ310_01535	COG0504	CTP synthase activity
HZ310_01540	COG4821	SIS domain
HZ310_01545	COG2204	response regulator
HZ310_01550	COG0191	fructose-bisphosphate aldolase activity
HZ310_01555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HZ310_01560	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HZ310_01565	COG1494	fructose-1,6-bisphosphatase
HZ310_01570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HZ310_01575	COG0254	rRNA binding
HZ310_01580	COG1435	thymidine kinase activity
HZ310_01585	COG0281	malic enzyme
HZ310_01590	COG0679	Auxin Efflux Carrier
HZ310_01595	COG0789	Transcriptional regulator
HZ310_01600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HZ310_01605	COG2890	protein-(glutamine-N5) methyltransferase activity
HZ310_01620	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HZ310_01625	COG0009	L-threonylcarbamoyladenylate synthase
HZ310_01630	COG1971	Probably functions as a manganese efflux pump
HZ310_01635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HZ310_01640	COG0698	ribose 5-phosphate isomerase
HZ310_01645	COG4475	Protein of unknown function (DUF436)
HZ310_01650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HZ310_01655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HZ310_01665	COG0356	it plays a direct role in the translocation of protons across the membrane
HZ310_01670	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HZ310_01675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HZ310_01680	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HZ310_01685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HZ310_01690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HZ310_01695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HZ310_01700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HZ310_01710	COG4836	Membrane
HZ310_01720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HZ310_01725	COG2385	sporulation resulting in formation of a cellular spore
HZ310_01730	COG2304	oxidoreductase activity
HZ310_01735	COG2304	oxidoreductase activity
HZ310_01740	COG0243	molybdopterin cofactor binding
HZ310_01745	COG2223	nitrite transmembrane transporter activity
HZ310_01750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HZ310_01755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HZ310_01760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HZ310_01765	COG0523	cobalamin synthesis protein
HZ310_01770	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HZ310_01810	COG1247	-acetyltransferase
HZ310_01815	COG0739	heme binding
HZ310_01820	COG0347	Belongs to the P(II) protein family
HZ310_01825	COG0004	ammonium transporteR
HZ310_01835	COG0765	amino acid transport
HZ310_01840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_01845	COG0477	Major facilitator Superfamily
HZ310_01850	COG0671	phosphoesterase, PA-phosphatase related
HZ310_01855	COG2814	Major facilitator Superfamily
HZ310_01860	COG1846	Transcriptional regulator
HZ310_01865	COG1609	Transcriptional regulator
HZ310_01870	COG1077	Cell shape determining protein MreB Mrl
HZ310_01875	COG4786	Flagellar basal body rod
HZ310_01880	COG4786	Flagellar basal body rod
HZ310_01885	COG0457	Tetratricopeptide repeat
HZ310_01890	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HZ310_01895	COG1970	mechanosensitive ion channel activity
HZ310_01910	COG0561	phosphatase activity
HZ310_01915	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_01915	COG2202	Pas domain
HZ310_01920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HZ310_01925	COG4715	Zinc finger, swim domain protein
HZ310_01935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HZ310_01940	COG2059	Chromate
HZ310_01945	COG2059	Chromate
HZ310_01950	COG1522	sequence-specific DNA binding
HZ310_01955	COG3527	Alpha-acetolactate decarboxylase
HZ310_01960	COG0028	Belongs to the TPP enzyme family
HZ310_01965	COG0583	DNA-binding transcription factor activity
HZ310_01970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HZ310_01975	COG1879	ABC-type sugar transport system periplasmic component
HZ310_01980	COG1172	Belongs to the binding-protein-dependent transport system permease family
HZ310_01985	COG1129	ABC transporter
HZ310_01990	COG1869	D-ribose catabolic process
HZ310_01995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZ310_02000	COG1609	Transcriptional regulator
HZ310_02015	COG0697	spore germination
HZ310_02020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HZ310_02030	COG2843	Capsule synthesis protein
HZ310_02040	COG0791	NLP P60 protein
HZ310_02045	COG0561	phosphatase activity
HZ310_02050	COG1316	TRANSCRIPTIONal
HZ310_02055	COG2814	Major facilitator Superfamily
HZ310_02070	COG0814	amino acid
HZ310_02075	COG0697	spore germination
HZ310_02080	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_02085	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HZ310_02090	COG1609	Transcriptional regulator
HZ310_02095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HZ310_02100	COG0800	Aldolase
HZ310_02105	COG0454	-acetyltransferase
HZ310_02115	COG2972	Histidine kinase
HZ310_02120	COG2197	response regulator
HZ310_02125	COG1653	transport
HZ310_02130	COG1175	transmembrane transport
HZ310_02140	COG1482	cell wall glycoprotein biosynthetic process
HZ310_02145	COG4193	domain, Protein
HZ310_02150	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HZ310_02155	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HZ310_02160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HZ310_02170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HZ310_02175	COG0463	Glycosyl transferase, family 2
HZ310_02175	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HZ310_02180	COG1682	transport, permease protein
HZ310_02185	COG1134	teichoic acid transport
HZ310_02190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HZ310_02195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HZ310_02205	COG1316	TRANSCRIPTIONal
HZ310_02215	COG2247	cell wall binding repeat
HZ310_02215	COG2385	sporulation resulting in formation of a cellular spore
HZ310_02220	COG2247	cell wall binding repeat
HZ310_02220	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZ310_02235	COG2244	polysaccharide biosynthetic process
HZ310_02240	COG0297	glycogen (starch) synthase activity
HZ310_02240	COG0438	transferase activity, transferring glycosyl groups
HZ310_02245	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HZ310_02250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZ310_02255	COG3307	-O-antigen
HZ310_02260	COG3206	protein involved in exopolysaccharide biosynthesis
HZ310_02265	COG1215	transferase activity, transferring glycosyl groups
HZ310_02270	COG0438	transferase activity, transferring glycosyl groups
HZ310_02275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HZ310_02280	COG1316	TRANSCRIPTIONal
HZ310_02285	COG1739	Uncharacterized protein family UPF0029
HZ310_02290	COG4585	Histidine kinase
HZ310_02295	COG2197	response regulator
HZ310_02300	COG1307	EDD domain protein, DegV family
HZ310_02305	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HZ310_02315	COG1040	competence protein
HZ310_02330	COG3418	PFAM FlgN family protein
HZ310_02335	COG4786	Flagellar basal body rod
HZ310_02335	COG1256	bacterial-type flagellum assembly
HZ310_02340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZ310_02350	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HZ310_02355	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HZ310_02360	COG1334	flagellar protein FlaG
HZ310_02365	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HZ310_02370	COG1516	flagellar protein fliS
HZ310_02385	COG0840	transmembrane signaling receptor activity
HZ310_02390	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HZ310_02415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZ310_02420	COG2010	Cytochrome c
HZ310_02425	COG2884	Cell division ATP-binding protein ftsE
HZ310_02430	COG2177	Part of the ABC transporter FtsEX involved in
HZ310_02435	COG3883	PFAM NLP P60 protein
HZ310_02435	COG0791	NLP P60 protein
HZ310_02440	COG0730	response to heat
HZ310_02445	COG0793	Belongs to the peptidase S41A family
HZ310_02445	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_02455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZ310_02460	COG1733	regulation of RNA biosynthetic process
HZ310_02465	COG0778	Nitroreductase
HZ310_02470	COG1113	amino acid transport
HZ310_02475	COG0463	Glycosyl transferase, family 2
HZ310_02480	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HZ310_02485	COG5002	protein histidine kinase activity
HZ310_02490	COG0745	RESPONSE REGULATOR receiver
HZ310_02500	COG2814	Major facilitator Superfamily
HZ310_02505	COG1309	transcriptional regulator
HZ310_02510	COG0574	Belongs to the PEP-utilizing enzyme family
HZ310_02510	COG3848	Pyruvate phosphate dikinase
HZ310_02515	COG4897	Protein conserved in bacteria
HZ310_02525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HZ310_02540	COG3595	metallopeptidase activity
HZ310_02545	COG1983	PspC domain protein
HZ310_02550	COG1950	PFAM Membrane protein of
HZ310_02555	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HZ310_02565	COG2188	Transcriptional regulator
HZ310_02570	COG0363	glucosamine-6-phosphate deaminase activity
HZ310_02575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HZ310_02580	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HZ310_02585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HZ310_02590	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HZ310_02595	COG0546	phosphoglycolate phosphatase activity
HZ310_02600	COG0110	maltose O-acetyltransferase activity
HZ310_02605	COG1959	2 iron, 2 sulfur cluster binding
HZ310_02610	COG2910	NAD(P)H-binding
HZ310_02620	COG4990	cell redox homeostasis
HZ310_02625	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HZ310_02630	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HZ310_02635	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HZ310_02640	COG0131	Imidazoleglycerol-phosphate dehydratase
HZ310_02645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HZ310_02650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HZ310_02655	COG0107	imidazoleglycerol-phosphate synthase activity
HZ310_02660	COG0140	phosphoribosyl-ATP diphosphatase activity
HZ310_02660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HZ310_02665	COG0457	Tetratricopeptide repeat
HZ310_02670	COG3883	PFAM NLP P60 protein
HZ310_02670	COG0791	NLP P60 protein
HZ310_02675	COG0492	ferredoxin-NADP+ reductase activity
HZ310_02680	COG1051	belongs to the nudix hydrolase family
HZ310_02685	COG1660	Displays ATPase and GTPase activities
HZ310_02690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HZ310_02695	COG1481	regulation of sporulation
HZ310_02700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_02705	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HZ310_02715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZ310_02720	COG0288	reversible hydration of carbon dioxide
HZ310_02725	COG0659	secondary active sulfate transmembrane transporter activity
HZ310_02730	COG1694	Mazg nucleotide pyrophosphohydrolase
HZ310_02735	COG1611	Belongs to the LOG family
HZ310_02740	COG0740	serine-type endopeptidase activity
HZ310_02755	COG1819	glycosyl
HZ310_02765	COG0726	polysaccharide deacetylase
HZ310_02770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZ310_02775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZ310_02780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_02795	COG1396	sequence-specific DNA binding
HZ310_02800	COG3944	biosynthesis protein
HZ310_02805	COG0489	protein tyrosine kinase activity
HZ310_02810	COG1086	Polysaccharide biosynthesis protein
HZ310_02815	COG0438	transferase activity, transferring glycosyl groups
HZ310_02820	COG1215	transferase activity, transferring glycosyl groups
HZ310_02825	COG0438	transferase activity, transferring glycosyl groups
HZ310_02835	COG1216	Glycosyl transferase, family 2
HZ310_02840	COG5039	Polysaccharide pyruvyl transferase
HZ310_02845	COG2244	polysaccharide biosynthetic process
HZ310_02850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HZ310_02855	COG0110	maltose O-acetyltransferase activity
HZ310_02860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZ310_02865	COG0747	negative chemotaxis
HZ310_02870	COG0601	transmembrane transport
HZ310_02875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZ310_02880	COG0444	Belongs to the ABC transporter superfamily
HZ310_02885	COG4608	Belongs to the ABC transporter superfamily
HZ310_02890	COG0534	Mate efflux family protein
HZ310_02900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HZ310_02905	COG2186	Transcriptional regulator
HZ310_02910	COG3829	transcription factor binding
HZ310_02915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HZ310_02920	COG0833	amino acid
HZ310_02925	COG2390	Transcriptional regulator
HZ310_02930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HZ310_02935	COG0126	phosphoglycerate kinase activity
HZ310_02940	COG0149	triose-phosphate isomerase activity
HZ310_02945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HZ310_02950	COG0148	phosphopyruvate hydratase activity
HZ310_02960	COG1131	(ABC) transporter
HZ310_02980	COG0456	acetyltransferase
HZ310_02990	COG2095	MarC family integral membrane protein
HZ310_02995	COG1510	regulation of RNA biosynthetic process
HZ310_03000	COG1125	glycine betaine transport
HZ310_03000	COG0517	IMP dehydrogenase activity
HZ310_03005	COG1174	glycine betaine transport
HZ310_03010	COG1732	Glycine betaine
HZ310_03015	COG1174	glycine betaine transport
HZ310_03020	COG1733	regulation of RNA biosynthetic process
HZ310_03025	COG1396	sequence-specific DNA binding
HZ310_03030	COG1396	sequence-specific DNA binding
HZ310_03035	COG1476	TRANSCRIPTIONal
HZ310_03040	COG2002	toxin-antitoxin pair type II binding
HZ310_03045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HZ310_03050	COG1647	Serine aminopeptidase, S33
HZ310_03055	COG0557	exoribonuclease II activity
HZ310_03060	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HZ310_03070	COG0270	DNA (cytosine-5-)-methyltransferase activity
HZ310_03090	COG1937	Protein conserved in bacteria
HZ310_03095	COG2608	mercury ion transmembrane transporter activity
HZ310_03100	COG2217	Heavy metal translocating P-type atpase
HZ310_03110	COG1027	Aspartate ammonia-lyase
HZ310_03115	COG4191	Histidine kinase
HZ310_03120	COG0784	Response regulator, receiver
HZ310_03125	COG3226	Transcriptional regulator
HZ310_03135	COG0803	Belongs to the bacterial solute-binding protein 9 family
HZ310_03140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HZ310_03145	COG1121	(ABC) transporter
HZ310_03150	COG2217	Heavy metal translocating P-type atpase
HZ310_03155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HZ310_03160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HZ310_03165	COG2860	membrane
HZ310_03170	COG0025	NhaP-type Na H and K H
HZ310_03175	COG1940	carbohydrate kinase activity
HZ310_03180	COG0656	L-ascorbic acid biosynthetic process
HZ310_03185	COG4149	molybdate abc transporter
HZ310_03190	COG0725	ABC transporter, periplasmic molybdate-binding protein
HZ310_03195	COG1368	sulfuric ester hydrolase activity
HZ310_03200	COG1988	membrane-bound metal-dependent
HZ310_03215	COG0531	amino acid
HZ310_03220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_03225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZ310_03230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZ310_03235	COG1120	ATPase activity
HZ310_03240	COG0745	RESPONSE REGULATOR receiver
HZ310_03245	COG2205	protein histidine kinase activity
HZ310_03250	COG1904	glucuronate isomerase
HZ310_03255	COG1609	Transcriptional regulator
HZ310_03260	COG0246	Mannitol dehydrogenase
HZ310_03265	COG2721	sulfolactate sulfo-lyase activity
HZ310_03275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_03280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZ310_03285	COG1120	ATPase activity
HZ310_03290	COG2096	Adenosyltransferase
HZ310_03295	COG4758	membrane
HZ310_03300	COG1842	Phage shock protein A
HZ310_03310	COG4758	membrane
HZ310_03315	COG4585	Histidine kinase
HZ310_03320	COG2197	response regulator
HZ310_03335	COG0814	amino acid
HZ310_03340	COG0697	spore germination
HZ310_03350	COG0114	fumarate hydratase activity
HZ310_03355	COG1309	transcriptional regulator
HZ310_03365	COG2770	Histidine kinase
HZ310_03365	COG2205	protein histidine kinase activity
HZ310_03370	COG0745	RESPONSE REGULATOR receiver
HZ310_03375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZ310_03380	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_03390	COG1120	ATPase activity
HZ310_03400	COG5577	PFAM Coat F domain
HZ310_03415	COG1024	Enoyl-CoA hydratase
HZ310_03415	COG1250	3-hydroxyacyl-CoA dehydrogenase
HZ310_03420	COG0183	Belongs to the thiolase family
HZ310_03425	COG1960	acyl-CoA dehydrogenase activity
HZ310_03430	COG1393	Belongs to the ArsC family
HZ310_03435	COG0509	glycine decarboxylation via glycine cleavage system
HZ310_03445	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HZ310_03450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_03460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HZ310_03465	COG2011	ABC-type metal ion transport system permease component
HZ310_03470	COG1464	Belongs to the NlpA lipoprotein family
HZ310_03475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HZ310_03485	COG0396	ATPase activity
HZ310_03490	COG0719	Fe-S assembly protein
HZ310_03495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HZ310_03500	COG0822	iron-sulfur transferase activity
HZ310_03505	COG0719	Fe-S assembly protein
HZ310_03530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HZ310_03540	COG2311	Membrane
HZ310_03545	COG0745	RESPONSE REGULATOR receiver
HZ310_03550	COG5002	protein histidine kinase activity
HZ310_03550	COG0642	Histidine kinase
HZ310_03575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_03580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZ310_03585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HZ310_03595	COG2356	endonuclease I
HZ310_03600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HZ310_03605	COG2814	Major facilitator Superfamily
HZ310_03610	COG2140	Oxalate decarboxylase
HZ310_03615	COG2508	Transcriptional regulator
HZ310_03620	COG1801	Protein of unknown function DUF72
HZ310_03625	COG0737	Belongs to the 5'-nucleotidase family
HZ310_03630	COG3377	Domain of unknown function (DUF1805)
HZ310_03640	COG0739	heme binding
HZ310_03645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HZ310_03655	COG4470	Protein conserved in bacteria
HZ310_03660	COG2445	Protein of unknown function DUF86
HZ310_03665	COG0647	UMP catabolic process
HZ310_03670	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HZ310_03675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HZ310_03680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZ310_03685	COG0460	homoserine dehydrogenase
HZ310_03690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HZ310_03695	COG0083	homoserine kinase activity
HZ310_03700	COG0823	Involved in the tonB-independent uptake of proteins
HZ310_03700	COG1506	peptidase
HZ310_03700	COG4946	Tricorn protease homolog
HZ310_03705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HZ310_03710	COG4837	Protein of unknown function (DUF1462)
HZ310_03720	COG1252	NADH dehydrogenase
HZ310_03725	COG4844	belongs to the
HZ310_03730	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HZ310_03735	COG0316	Belongs to the HesB IscA family
HZ310_03760	COG0492	ferredoxin-NADP+ reductase activity
HZ310_03765	COG1252	NADH dehydrogenase
HZ310_03780	COG3584	3D domain protein
HZ310_03785	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HZ310_03790	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HZ310_03795	COG2056	Na+-H+ antiporter family
HZ310_03800	COG4326	sporulation control protein
HZ310_03805	COG1268	BioY protein
HZ310_03810	COG0686	Belongs to the AlaDH PNT family
HZ310_03815	COG2508	Transcriptional regulator
HZ310_03815	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HZ310_03820	COG4842	Belongs to the WXG100 family
HZ310_03825	COG5417	Belongs to the EsaB family
HZ310_03830	COG4499	WXG100 protein secretion system (Wss), protein YukC
HZ310_03835	COG1674	ftsk spoiiie
HZ310_03835	COG0433	COG0433 Predicted ATPase
HZ310_03840	COG1511	domain protein
HZ310_03850	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_03855	COG1418	mRNA catabolic process
HZ310_03870	COG0628	permease
HZ310_03890	COG5506	Protein of unknown function (DUF1694)
HZ310_03895	COG1335	isochorismatase
HZ310_03900	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HZ310_03905	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
HZ310_03920	COG0142	geranyltranstransferase activity
HZ310_03930	COG4585	Histidine kinase
HZ310_03935	COG2197	response regulator
HZ310_03940	COG2050	protein possibly involved in aromatic compounds catabolism
HZ310_03945	COG1320	monovalent cation:proton antiporter activity
HZ310_03950	COG2212	antiporter activity
HZ310_03955	COG1863	multisubunit Na H antiporter MnhE subunit
HZ310_03960	COG0651	ATP synthesis coupled electron transport
HZ310_03965	COG1006	Multisubunit Na H antiporter MnhC subunit
HZ310_03970	COG2111	Na H antiporter
HZ310_03975	COG2111	Na H antiporter
HZ310_03975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HZ310_03985	COG3493	citrate carrier protein
HZ310_04010	COG4565	transcriptional regulatory protein
HZ310_04015	COG3290	protein histidine kinase activity
HZ310_04030	COG3011	Protein conserved in bacteria
HZ310_04035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HZ310_04040	COG2814	Major facilitator Superfamily
HZ310_04045	COG5018	Exonuclease
HZ310_04060	COG2205	protein histidine kinase activity
HZ310_04065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HZ310_04075	COG2267	carboxylic ester hydrolase activity
HZ310_04080	COG1522	sequence-specific DNA binding
HZ310_04085	COG0436	Aminotransferase
HZ310_04090	COG1098	S1 RNA binding domain
HZ310_04095	COG2155	Conserved Protein
HZ310_04100	COG1979	alcohol dehydrogenase
HZ310_04105	COG1979	alcohol dehydrogenase
HZ310_04110	COG0166	Belongs to the GPI family
HZ310_04130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HZ310_04140	COG2738	Putative neutral zinc metallopeptidase
HZ310_04145	COG1253	flavin adenine dinucleotide binding
HZ310_04150	COG0432	Pfam Uncharacterised protein family UPF0047
HZ310_04155	COG2070	2-Nitropropane dioxygenase
HZ310_04170	COG0840	transmembrane signaling receptor activity
HZ310_04175	COG0840	transmembrane signaling receptor activity
HZ310_04180	COG0840	transmembrane signaling receptor activity
HZ310_04185	COG0840	transmembrane signaling receptor activity
HZ310_04190	COG0693	protein deglycase activity
HZ310_04195	COG0673	inositol 2-dehydrogenase activity
HZ310_04205	COG0628	permease
HZ310_04210	COG1968	undecaprenyl-diphosphatase activity
HZ310_04220	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HZ310_04235	COG1396	sequence-specific DNA binding
HZ310_04255	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HZ310_04265	COG1595	DNA-templated transcription, initiation
HZ310_04270	COG5484	DNA packaging
HZ310_04275	COG1783	phage Terminase large subunit
HZ310_04280	COG5518	Phage portal protein
HZ310_04285	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HZ310_04290	COG4653	Phage capsid family
HZ310_04345	COG5280	Phage tail tape measure protein TP901
HZ310_04345	COG3953	SLT domain
HZ310_04345	COG3953	SLT domain
HZ310_04345	COG5280	Phage tail tape measure protein TP901
HZ310_04350	COG1652	LysM domain
HZ310_04355	COG4193	domain, Protein
HZ310_04365	COG3628	GPW Gp25 family protein
HZ310_04370	COG3299	homolog of phage Mu protein gp47
HZ310_04375	COG3778	Protein conserved in bacteria
HZ310_04415	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_04415	COG5632	N-Acetylmuramoyl-L-alanine amidase
HZ310_04535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZ310_04535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZ310_04590	COG1780	Probably involved in ribonucleotide reductase function
HZ310_04595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZ310_04605	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZ310_04630	COG0756	dUTP diphosphatase activity
HZ310_04650	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HZ310_04740	COG0582	viral genome integration into host DNA
HZ310_04825	COG1705	Flagellar rod assembly protein muramidase FlgJ
HZ310_04890	COG4974	Belongs to the 'phage' integrase family
HZ310_04900	COG1510	regulation of RNA biosynthetic process
HZ310_04905	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_04910	COG1454	alcohol dehydrogenase
HZ310_04915	COG2318	DinB family
HZ310_04920	COG1585	Membrane protein implicated in regulation of membrane protease activity
HZ310_04925	COG2268	Band 7 protein
HZ310_04930	COG0772	Belongs to the SEDS family
HZ310_04935	COG0772	Belongs to the SEDS family
HZ310_04940	COG3339	Conserved Protein
HZ310_04945	COG1247	-acetyltransferase
HZ310_04950	COG3859	Proton-coupled thiamine transporter YuaJ
HZ310_05075	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
HZ310_05080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HZ310_05085	COG1575	Belongs to the MenA family. Type 1 subfamily
HZ310_05090	COG1169	isochorismate synthase
HZ310_05095	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HZ310_05100	COG0596	Alpha beta hydrolase
HZ310_05105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HZ310_05110	COG0318	PFAM AMP-dependent synthetase and ligase
HZ310_05115	COG4948	Mandelate Racemase Muconate Lactonizing
HZ310_05130	COG1294	oxidase, subunit
HZ310_05135	COG1271	oxidase subunit
HZ310_05150	COG0803	Belongs to the bacterial solute-binding protein 9 family
HZ310_05150	COG3443	Belongs to the bacterial solute-binding protein 9 family
HZ310_05155	COG0288	reversible hydration of carbon dioxide
HZ310_05160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HZ310_05165	COG1854	S-ribosylhomocysteine lyase activity
HZ310_05180	COG0783	Belongs to the Dps family
HZ310_05190	COG4824	toxin secretion phage lysis holin
HZ310_05205	COG2310	stress, protein
HZ310_05210	COG0494	nUDIX hydrolase
HZ310_05215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HZ310_05220	COG1116	anion transmembrane transporter activity
HZ310_05225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HZ310_05245	COG1233	COG1233 Phytoene dehydrogenase and related
HZ310_05250	COG1506	peptidase
HZ310_05260	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HZ310_05265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HZ310_05270	COG0367	asparagine synthase
HZ310_05275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HZ310_05280	COG2267	carboxylic ester hydrolase activity
HZ310_05290	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HZ310_05295	COG1242	4 iron, 4 sulfur cluster binding
HZ310_05310	COG1725	Transcriptional regulator
HZ310_05315	COG1131	(ABC) transporter
HZ310_05325	COG1136	(ABC) transporter
HZ310_05330	COG0577	efflux transmembrane transporter activity
HZ310_05335	COG2433	Pfam Transposase IS66
HZ310_05340	COG2202	Pas domain
HZ310_05340	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_05350	COG0495	leucyl-tRNA aminoacylation
HZ310_05355	COG1073	alpha beta
HZ310_05360	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZ310_05365	COG0395	ABC-type sugar transport system, permease component
HZ310_05370	COG1653	transport
HZ310_05375	COG0656	L-ascorbic acid biosynthetic process
HZ310_05380	COG2814	Major facilitator Superfamily
HZ310_05385	COG1733	regulation of RNA biosynthetic process
HZ310_05390	COG2207	Transcriptional regulator
HZ310_05395	COG4209	transmembrane transport
HZ310_05400	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HZ310_05405	COG1653	transport
HZ310_05410	COG0673	inositol 2-dehydrogenase activity
HZ310_05415	COG5578	integral membrane protein
HZ310_05420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZ310_05430	COG3196	Protein conserved in bacteria
HZ310_05435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HZ310_05445	COG2081	HI0933 family
HZ310_05450	COG2244	polysaccharide biosynthetic process
HZ310_05455	COG1187	pseudouridine synthase activity
HZ310_05460	COG1349	DNA-binding transcription factor activity
HZ310_05465	COG2252	PERMEase
HZ310_05470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HZ310_05475	COG3340	Belongs to the peptidase S51 family
HZ310_05480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HZ310_05485	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HZ310_05495	COG1597	lipid kinase activity
HZ310_05500	COG0510	thiamine kinase activity
HZ310_05510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HZ310_05515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZ310_05520	COG0281	malic enzyme
HZ310_05525	COG5584	Small secreted protein
HZ310_05530	COG1363	Peptidase, m42
HZ310_05545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_05550	COG4848	Belongs to the UPF0354 family
HZ310_05555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZ310_05560	COG1674	ftsk spoiiie
HZ310_05565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HZ310_05570	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HZ310_05575	COG4980	gas vesicle protein
HZ310_05580	COG3118	belongs to the thioredoxin family
HZ310_05585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HZ310_05585	COG1605	Chorismate mutase
HZ310_05590	COG1609	Transcriptional regulator
HZ310_05595	COG0123	including yeast histone deacetylase and acetoin utilization protein
HZ310_05600	COG0517	IMP dehydrogenase activity
HZ310_05605	COG0454	-acetyltransferase
HZ310_05610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HZ310_05615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HZ310_05620	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HZ310_05630	COG1335	isochorismatase
HZ310_05640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HZ310_05645	COG1956	GAF domain-containing protein
HZ310_05650	COG1309	transcriptional regulator
HZ310_05655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HZ310_05660	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HZ310_05665	COG1114	Component of the transport system for branched-chain amino acids
HZ310_05670	COG1114	Component of the transport system for branched-chain amino acids
HZ310_05675	COG1104	cysteine desulfurase activity
HZ310_05680	COG0301	tRNA thio-modification
HZ310_05690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HZ310_05695	COG1279	arginine transmembrane transporter activity
HZ310_05705	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZ310_05710	COG0402	S-adenosylhomocysteine deaminase activity
HZ310_05715	COG0577	efflux transmembrane transporter activity
HZ310_05720	COG1136	(ABC) transporter
HZ310_05725	COG1695	Transcriptional regulator
HZ310_05730	COG0772	Belongs to the SEDS family
HZ310_05735	COG2205	protein histidine kinase activity
HZ310_05740	COG0745	RESPONSE REGULATOR receiver
HZ310_05745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_05750	COG2197	response regulator
HZ310_05755	COG4585	Histidine kinase
HZ310_05760	COG3239	Fatty acid desaturase
HZ310_05770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HZ310_05775	COG0616	signal peptide processing
HZ310_05780	COG1714	RDD family
HZ310_05790	COG3874	Sporulation protein YtfJ
HZ310_05795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HZ310_05800	COG0827	DNA restriction-modification system
HZ310_05805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HZ310_05810	COG0521	Mo-molybdopterin cofactor biosynthetic process
HZ310_05815	COG0137	argininosuccinate synthase activity
HZ310_05820	COG0165	Argininosuccinate lyase
HZ310_05830	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_05835	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HZ310_05840	COG4109	DRTGG domain
HZ310_05850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HZ310_05870	COG0587	DNA-directed DNA polymerase activity
HZ310_05875	COG0281	malic enzyme
HZ310_05880	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HZ310_05885	COG0825	malonyl-CoA metabolic process
HZ310_05890	COG0205	6-phosphofructokinase activity
HZ310_05900	COG3030	protein affecting phage T7 exclusion by the F plasmid
HZ310_05905	COG0628	permease
HZ310_05910	COG2707	UPF0756 membrane protein
HZ310_05915	COG0372	Belongs to the citrate synthase family
HZ310_05920	COG0538	isocitrate dehydrogenase activity
HZ310_05925	COG0039	L-malate dehydrogenase activity
HZ310_05930	COG0745	RESPONSE REGULATOR receiver
HZ310_05935	COG5002	protein histidine kinase activity
HZ310_05940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZ310_05940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZ310_05945	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HZ310_05950	COG1971	Probably functions as a manganese efflux pump
HZ310_05955	COG0237	dephospho-CoA kinase activity
HZ310_05960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HZ310_05965	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HZ310_05975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HZ310_05980	COG3611	Membrane attachment protein
HZ310_05985	COG1484	DNA-dependent DNA replication
HZ310_05990	COG0398	Pfam SNARE associated Golgi protein
HZ310_06000	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HZ310_06010	COG1011	Hydrolase
HZ310_06015	COG3275	phosphorelay sensor kinase activity
HZ310_06020	COG3279	Response regulator of the LytR AlgR family
HZ310_06030	COG1346	cytolysis
HZ310_06035	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HZ310_06040	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HZ310_06045	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HZ310_06050	COG3326	Membrane
HZ310_06060	COG1363	Peptidase, m42
HZ310_06065	COG1966	Carbon starvation protein
HZ310_06075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZ310_06080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HZ310_06085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZ310_06085	COG0072	phenylalanine-tRNA ligase activity
HZ310_06090	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HZ310_06095	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HZ310_06100	COG1286	toxin biosynthetic process
HZ310_06105	COG1796	DNA polymerase
HZ310_06105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HZ310_06110	COG1193	negative regulation of DNA recombination
HZ310_06115	COG3766	membrane
HZ310_06125	COG0318	PFAM AMP-dependent synthetase and ligase
HZ310_06130	COG1309	transcriptional regulator
HZ310_06135	COG1024	Enoyl-CoA hydratase
HZ310_06140	COG2086	electron transfer activity
HZ310_06145	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HZ310_06150	COG3534	alpha-L-arabinofuranosidase
HZ310_06155	COG3118	belongs to the thioredoxin family
HZ310_06160	COG0322	excinuclease ABC activity
HZ310_06165	COG0527	aspartate kinase activity
HZ310_06170	COG1719	4-vinyl reductase, 4VR
HZ310_06175	COG2009	succinate dehydrogenase
HZ310_06180	COG1053	succinate dehydrogenase
HZ310_06185	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HZ310_06190	COG0824	Thioesterase
HZ310_06200	COG2828	Protein conserved in bacteria
HZ310_06205	COG0583	DNA-binding transcription factor activity
HZ310_06210	COG2851	Citrate transporter
HZ310_06215	COG2197	response regulator
HZ310_06220	COG1846	Transcriptional regulator
HZ310_06225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HZ310_06230	COG5401	PFAM Sporulation and spore germination
HZ310_06235	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HZ310_06240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HZ310_06245	COG0622	Phosphoesterase
HZ310_06270	COG1696	Membrane protein involved in D-alanine export
HZ310_06275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HZ310_06280	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HZ310_06285	COG3339	Conserved Protein
HZ310_06290	COG2706	6-phosphogluconolactonase activity
HZ310_06295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HZ310_06300	COG0028	Belongs to the TPP enzyme family
HZ310_06305	COG0440	acetolactate synthase activity
HZ310_06310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HZ310_06315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HZ310_06320	COG0473	3-isopropylmalate dehydrogenase activity
HZ310_06325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HZ310_06330	COG0066	3-isopropylmalate dehydratase activity
HZ310_06335	COG0457	Tetratricopeptide repeat
HZ310_06335	COG1477	protein flavinylation
HZ310_06340	COG0544	peptidyl-prolyl cis-trans isomerase activity
HZ310_06345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HZ310_06350	COG1067	ATP-dependent peptidase activity
HZ310_06350	COG0470	DNA polymerase III
HZ310_06355	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HZ310_06360	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HZ310_06370	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HZ310_06375	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HZ310_06380	COG0181	hydroxymethylbilane synthase activity
HZ310_06385	COG1587	Uroporphyrinogen-III synthase
HZ310_06390	COG0113	porphobilinogen synthase activity
HZ310_06395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HZ310_06400	COG1388	LysM domain
HZ310_06405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HZ310_06415	COG0525	valine-tRNA ligase activity
HZ310_06420	COG0285	dihydrofolate synthase activity
HZ310_06425	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HZ310_06435	COG0424	maF-like protein
HZ310_06445	COG1077	Cell shape determining protein MreB Mrl
HZ310_06455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HZ310_06460	COG0850	regulation of cytokinetic process
HZ310_06465	COG2894	cell division
HZ310_06470	COG0739	heme binding
HZ310_06475	COG1994	Peptidase M50
HZ310_06480	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HZ310_06485	COG2868	ribosomal protein
HZ310_06490	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HZ310_06495	COG3290	protein histidine kinase activity
HZ310_06500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HZ310_06505	COG4492	Belongs to the UPF0735 family
HZ310_06510	COG0077	Prephenate dehydratase
HZ310_06515	COG1827	regulation of RNA biosynthetic process
HZ310_06520	COG1104	cysteine desulfurase activity
HZ310_06525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HZ310_06530	COG0157	Belongs to the NadC ModD family
HZ310_06535	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HZ310_06540	COG1388	LysM domain
HZ310_06555	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HZ310_06570	COG2112	serine threonine protein kinase
HZ310_06580	COG0632	four-way junction helicase activity
HZ310_06585	COG2255	four-way junction helicase activity
HZ310_06595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HZ310_06600	COG0343	queuine tRNA-ribosyltransferase activity
HZ310_06605	COG1862	Preprotein translocase
HZ310_06615	COG2323	membrane
HZ310_06620	COG2244	polysaccharide biosynthetic process
HZ310_06630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZ310_06630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HZ310_06635	COG0490	domain, Protein
HZ310_06640	COG5416	Lipopolysaccharide assembly protein A domain
HZ310_06645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HZ310_06645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HZ310_06650	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HZ310_06655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HZ310_06660	COG1490	D-aminoacyl-tRNA deacylase activity
HZ310_06665	COG3103	Sh3 type 3 domain protein
HZ310_06665	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZ310_06665	COG4991	sh3 domain protein
HZ310_06675	COG0124	histidyl-tRNA synthetase
HZ310_06690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HZ310_06695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HZ310_06700	COG1959	2 iron, 2 sulfur cluster binding
HZ310_06705	COG1104	cysteine desulfurase activity
HZ310_06710	COG0482	sulfurtransferase activity
HZ310_06715	COG0457	Tetratricopeptide repeat
HZ310_06720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HZ310_06725	COG3881	PFAM PRC-barrel domain
HZ310_06740	COG0765	amino acid transport
HZ310_06745	COG0765	amino acid transport
HZ310_06750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_06755	COG1126	abc transporter atp-binding protein
HZ310_06760	COG0628	permease
HZ310_06765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HZ310_06770	COG4472	Bacterial protein of unknown function (DUF965)
HZ310_06775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HZ310_06780	COG3906	Belongs to the UPF0473 family
HZ310_06785	COG1268	BioY protein
HZ310_06790	COG0318	PFAM AMP-dependent synthetase and ligase
HZ310_06795	COG0183	Belongs to the thiolase family
HZ310_06800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HZ310_06805	COG4122	O-methyltransferase activity
HZ310_06820	COG0572	uridine kinase
HZ310_06830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HZ310_06835	COG0768	penicillin binding
HZ310_06850	COG2226	methyltransferase
HZ310_06855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HZ310_06860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HZ310_06865	COG0626	cystathionine gamma-synthase activity
HZ310_06890	COG2226	methyltransferase
HZ310_06895	COG1063	alcohol dehydrogenase
HZ310_06900	COG0583	DNA-binding transcription factor activity
HZ310_06915	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_06925	COG1063	alcohol dehydrogenase
HZ310_06930	COG3546	catalase activity
HZ310_06940	COG0765	amino acid transport
HZ310_06945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_06950	COG1126	abc transporter atp-binding protein
HZ310_06955	COG1960	acyl-CoA dehydrogenase activity
HZ310_06960	COG2602	Beta-lactamase
HZ310_07000	COG1733	regulation of RNA biosynthetic process
HZ310_07005	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
HZ310_07010	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HZ310_07020	COG1609	Transcriptional regulator
HZ310_07035	COG2160	L-arabinose isomerase activity
HZ310_07065	COG0726	polysaccharide deacetylase
HZ310_07110	COG0457	Tetratricopeptide repeat
HZ310_07120	COG2755	lipolytic protein G-D-S-L family
HZ310_07135	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HZ310_07140	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HZ310_07145	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HZ310_07150	COG1534	Rna-binding protein
HZ310_07155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HZ310_07160	COG1713	HD superfamily hydrolase involved in NAD metabolism
HZ310_07165	COG0799	negative regulation of ribosome biogenesis
HZ310_07170	COG2226	methyltransferase
HZ310_07175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HZ310_07180	COG1555	photosystem II stabilization
HZ310_07185	COG2131	deaminase
HZ310_07190	COG2333	competence protein COMEC
HZ310_07190	COG0658	competence protein
HZ310_07200	COG1466	dna polymerase III delta subunit
HZ310_07205	COG0268	Binds directly to 16S ribosomal RNA
HZ310_07210	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HZ310_07215	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZ310_07225	COG0481	GTPase activity
HZ310_07230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZ310_07235	COG1420	regulation of RNA biosynthetic process
HZ310_07240	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HZ310_07245	COG0443	Heat shock 70 kDa protein
HZ310_07250	COG0484	heat shock protein binding
HZ310_07255	COG2264	protein methyltransferase activity
HZ310_07260	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HZ310_07265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZ310_07270	COG1283	sodium-dependent phosphate transmembrane transporter activity
HZ310_07280	COG1610	YqeY-like protein
HZ310_07285	COG1030	water channel activity
HZ310_07290	COG4864	UPF0365 protein
HZ310_07310	COG0561	phosphatase activity
HZ310_07315	COG1702	phosphate starvation-inducible protein PhoH
HZ310_07320	COG1480	7TM receptor with intracellular HD hydrolase
HZ310_07325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HZ310_07330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HZ310_07335	COG0295	cytidine deaminase activity
HZ310_07340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HZ310_07350	COG1381	Involved in DNA repair and RecF pathway recombination
HZ310_07355	COG0752	glycyl-tRNA synthetase alpha subunit
HZ310_07360	COG0751	glycine-tRNA ligase activity
HZ310_07365	COG0517	IMP dehydrogenase activity
HZ310_07370	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HZ310_07375	COG1671	Belongs to the UPF0178 family
HZ310_07380	COG0358	DNA primase activity
HZ310_07385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HZ310_07390	COG2010	Cytochrome c
HZ310_07395	COG2384	SAM-dependent methyltransferase
HZ310_07400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HZ310_07405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HZ310_07415	COG0513	Belongs to the DEAD box helicase family
HZ310_07420	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HZ310_07430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZ310_07435	COG1121	(ABC) transporter
HZ310_07440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HZ310_07445	COG0735	belongs to the Fur family
HZ310_07450	COG1940	carbohydrate kinase activity
HZ310_07455	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
HZ310_07460	COG4709	membrane
HZ310_07465	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HZ310_07470	COG1388	LysM domain
HZ310_07475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZ310_07480	COG5521	maltodextrose utilization protein MalA
HZ310_07485	COG2839	Protein conserved in bacteria
HZ310_07490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HZ310_07495	COG0477	Major facilitator Superfamily
HZ310_07505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HZ310_07510	COG0573	inorganic phosphate transmembrane transporter activity
HZ310_07515	COG0581	inorganic phosphate transmembrane transporter activity
HZ310_07520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HZ310_07525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HZ310_07530	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HZ310_07540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HZ310_07545	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HZ310_07560	COG0457	Tetratricopeptide repeat
HZ310_07560	COG0705	Rhomboid family
HZ310_07565	COG4483	Protein conserved in bacteria
HZ310_07570	COG1940	carbohydrate kinase activity
HZ310_07575	COG1368	sulfuric ester hydrolase activity
HZ310_07580	COG2866	Carboxypeptidase
HZ310_07585	COG2814	Major facilitator Superfamily
HZ310_07590	COG0011	TIGRFAM Protein of
HZ310_07600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZ310_07615	COG1393	Belongs to the ArsC family
HZ310_07625	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_07630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HZ310_07635	COG1459	type II secretion system
HZ310_07640	COG4537	Required for transformation and DNA binding
HZ310_07645	COG4970	Tfp pilus assembly protein FimT
HZ310_07675	COG0681	Belongs to the peptidase S26 family
HZ310_07700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HZ310_07705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HZ310_07710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HZ310_07715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HZ310_07720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZ310_07725	COG0095	Lipoate-protein ligase
HZ310_07730	COG1321	iron dependent repressor
HZ310_07735	COG1752	Esterase of the alpha-beta hydrolase superfamily
HZ310_07745	COG3872	metal-dependent enzyme
HZ310_07755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HZ310_07760	COG0006	proline dipeptidase activity
HZ310_07765	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HZ310_07775	COG3854	ATPases associated with a variety of cellular activities
HZ310_07815	COG0511	ligase activity, forming carbon-carbon bonds
HZ310_07820	COG0439	Biotin carboxylase
HZ310_07825	COG1302	Protein conserved in bacteria
HZ310_07830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HZ310_07835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HZ310_07840	COG1570	exodeoxyribonuclease VII activity
HZ310_07845	COG1722	exodeoxyribonuclease VII activity
HZ310_07850	COG0142	geranyltranstransferase activity
HZ310_07855	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HZ310_07860	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HZ310_07865	COG1438	arginine binding
HZ310_07870	COG0497	DNA recombination
HZ310_07875	COG0750	zinc metalloprotease
HZ310_07880	COG0745	RESPONSE REGULATOR receiver
HZ310_07885	COG0457	Tetratricopeptide repeat
HZ310_07890	COG0584	glycerophosphoryl diester phosphodiesterase
HZ310_07900	COG3290	protein histidine kinase activity
HZ310_07900	COG3829	transcription factor binding
HZ310_07905	COG0280	phosphate acetyltransferase
HZ310_07910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HZ310_07915	COG3426	butyrate kinase activity
HZ310_07920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZ310_07925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HZ310_07935	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZ310_07945	COG1597	lipid kinase activity
HZ310_07955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_07960	COG0765	amino acid transport
HZ310_07965	COG1126	abc transporter atp-binding protein
HZ310_07970	COG4129	membrane
HZ310_07975	COG1376	ErfK ybiS ycfS ynhG family protein
HZ310_07985	COG0346	lactoylglutathione lyase activity
HZ310_07995	COG2195	Cleaves the N-terminal amino acid of tripeptides
HZ310_08005	COG0706	membrane insertase activity
HZ310_08020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HZ310_08025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HZ310_08030	COG4975	Glucose uptake
HZ310_08035	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_08040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZ310_08045	COG1447	Phosphotransferase system cellobiose-specific component IIA
HZ310_08050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HZ310_08055	COG2723	6-phospho-beta-galactosidase activity
HZ310_08060	COG2188	Transcriptional regulator
HZ310_08065	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HZ310_08070	COG1234	tRNA 3'-trailer cleavage
HZ310_08075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZ310_08080	COG0596	Alpha beta hydrolase
HZ310_08085	COG1902	pentaerythritol trinitrate reductase activity
HZ310_08090	COG4187	Peptidase family M20/M25/M40
HZ310_08100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HZ310_08105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZ310_08110	COG0300	oxidoreductase activity
HZ310_08120	COG1072	(Pantothenic acid kinase))
HZ310_08125	COG2211	Major facilitator Superfamily
HZ310_08135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HZ310_08145	COG0456	acetyltransferase
HZ310_08150	COG0456	acetyltransferase
HZ310_08150	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HZ310_08155	COG4305	rare lipoprotein A
HZ310_08160	COG4918	Iron-sulphur cluster biosynthesis
HZ310_08170	COG0457	Tetratricopeptide repeat
HZ310_08175	COG1073	alpha beta
HZ310_08185	COG0667	Aldo Keto reductase
HZ310_08190	COG0494	nUDIX hydrolase
HZ310_08195	COG1379	DNA repair
HZ310_08200	COG2153	protein acetylation
HZ310_08210	COG1404	Belongs to the peptidase S8 family
HZ310_08215	COG1300	Membrane
HZ310_08220	COG0735	belongs to the Fur family
HZ310_08230	COG4974	Belongs to the 'phage' integrase family
HZ310_08235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HZ310_08240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HZ310_08245	COG1686	Belongs to the peptidase S11 family
HZ310_08255	COG2172	sigma factor antagonist activity
HZ310_08260	COG1191	sigma factor activity
HZ310_08280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HZ310_08295	COG0697	spore germination
HZ310_08300	COG0019	diaminopimelate decarboxylase activity
HZ310_08305	COG4086	secreted protein
HZ310_08310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HZ310_08315	COG2814	Major facilitator Superfamily
HZ310_08335	COG0307	riboflavin synthase, alpha
HZ310_08340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZ310_08340	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZ310_08345	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HZ310_08350	COG0456	acetyltransferase
HZ310_08355	COG1547	Domain of unknown function (DUF309)
HZ310_08365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HZ310_08370	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HZ310_08380	COG1686	Belongs to the peptidase S11 family
HZ310_08385	COG2715	membrane protein required for spore maturation
HZ310_08390	COG0700	Nucleoside recognition
HZ310_08395	COG1187	pseudouridine synthase activity
HZ310_08400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_08405	COG1333	cytochrome c biogenesis protein
HZ310_08410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HZ310_08415	COG0745	RESPONSE REGULATOR receiver
HZ310_08420	COG5002	protein histidine kinase activity
HZ310_08425	COG1595	DNA-templated transcription, initiation
HZ310_08435	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_08435	COG5632	N-Acetylmuramoyl-L-alanine amidase
HZ310_08440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HZ310_08445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HZ310_08450	COG1141	Ferredoxin
HZ310_08455	COG4955	Helix-turn-helix domain
HZ310_08460	COG0514	ATP-dependent DNA helicase (RecQ)
HZ310_08465	COG1266	CAAX protease self-immunity
HZ310_08470	COG1388	LysM domain
HZ310_08480	COG1408	metallophosphoesterase
HZ310_08485	COG4862	establishment of competence for transformation
HZ310_08490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HZ310_08495	COG0492	ferredoxin-NADP+ reductase activity
HZ310_08500	COG2339	peptidase activity
HZ310_08510	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_08510	COG3773	Cell wall hydrolase
HZ310_08515	COG2959	enzyme of heme biosynthesis
HZ310_08520	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
HZ310_08530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HZ310_08535	COG0539	negative regulation of cytoplasmic translation
HZ310_08540	COG1304	FMN binding
HZ310_08565	COG1160	GTP binding
HZ310_08570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HZ310_08585	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HZ310_08590	COG0776	regulation of translation
HZ310_08595	COG0302	gtp cyclohydrolase
HZ310_08605	COG0142	geranyltranstransferase activity
HZ310_08610	COG2226	methyltransferase
HZ310_08615	COG0142	geranyltranstransferase activity
HZ310_08620	COG0105	UTP biosynthetic process
HZ310_08625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HZ310_08630	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HZ310_08635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HZ310_08640	COG4401	Chorismate mutase type I
HZ310_08650	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HZ310_08655	COG0134	indole-3-glycerol-phosphate synthase activity
HZ310_08660	COG0135	phosphoribosylanthranilate isomerase activity
HZ310_08665	COG0133	tryptophan synthase activity
HZ310_08670	COG0159	tryptophan synthase activity
HZ310_08675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HZ310_08680	COG0287	Prephenate dehydrogenase
HZ310_08685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HZ310_08690	COG0457	Tetratricopeptide repeat
HZ310_08695	COG5582	Belongs to the UPF0302 family
HZ310_08705	COG0723	plastoquinol--plastocyanin reductase activity
HZ310_08710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HZ310_08715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HZ310_08715	COG2010	Cytochrome c
HZ310_08720	COG4347	Protein of unknown function (DUF1405)
HZ310_08730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZ310_08735	COG1694	Mazg nucleotide pyrophosphohydrolase
HZ310_08740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HZ310_08745	COG1803	Methylglyoxal synthase
HZ310_08750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HZ310_08755	COG0438	transferase activity, transferring glycosyl groups
HZ310_08760	COG0617	tRNA 3'-terminal CCA addition
HZ310_08770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HZ310_08775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HZ310_08780	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HZ310_08785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HZ310_08785	COG1199	ATP-dependent helicase activity
HZ310_08795	COG5353	protein conserved in bacteria
HZ310_08800	COG0017	Asparaginyl-tRNA synthetase
HZ310_08805	COG3935	DnaD domain protein
HZ310_08810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HZ310_08820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HZ310_08820	COG4499	WXG100 protein secretion system (Wss), protein YukC
HZ310_08825	COG3331	DNA recombination
HZ310_08855	COG0071	Belongs to the small heat shock protein (HSP20) family
HZ310_08860	COG2190	(PTS) system
HZ310_08865	COG1902	pentaerythritol trinitrate reductase activity
HZ310_08870	COG1111	helicase
HZ310_08870	COG1205	dead DEAH box helicase
HZ310_08875	COG3359	exonuclease
HZ310_08885	COG4474	Belongs to the UPF0398 family
HZ310_08890	COG3599	regulation of cell shape
HZ310_08900	COG0116	Belongs to the methyltransferase superfamily
HZ310_08910	COG1199	ATP-dependent helicase activity
HZ310_08915	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HZ310_08920	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HZ310_08925	COG2233	PERMEase
HZ310_08930	COG0726	polysaccharide deacetylase
HZ310_08935	COG3424	synthase
HZ310_08940	COG1755	Isoprenylcysteine carboxyl methyltransferase
HZ310_08950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HZ310_08960	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HZ310_08970	COG0328	RNA-DNA hybrid ribonuclease activity
HZ310_08975	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HZ310_08980	COG0328	RNA-DNA hybrid ribonuclease activity
HZ310_08995	COG1278	Cold shock
HZ310_09005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HZ310_09010	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HZ310_09015	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HZ310_09020	COG0386	Belongs to the glutathione peroxidase family
HZ310_09025	COG1418	mRNA catabolic process
HZ310_09030	COG1413	lyase activity
HZ310_09035	COG0129	dihydroxy-acid dehydratase activity
HZ310_09045	COG2521	methyltransferase
HZ310_09045	COG2136	Putative SAM-dependent methyltransferase
HZ310_09055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HZ310_09060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HZ310_09065	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HZ310_09070	COG0204	Acyl-transferase
HZ310_09075	COG1272	protein, Hemolysin III
HZ310_09080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
HZ310_09085	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HZ310_09100	COG1999	signal sequence binding
HZ310_09105	COG2755	lipolytic protein G-D-S-L family
HZ310_09110	COG4698	Protein conserved in bacteria
HZ310_09130	COG1846	Transcriptional regulator
HZ310_09135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HZ310_09140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HZ310_09145	COG1086	Polysaccharide biosynthesis protein
HZ310_09155	COG4641	Protein conserved in bacteria
HZ310_09170	COG0463	Glycosyl transferase, family 2
HZ310_09175	COG3829	transcription factor binding
HZ310_09180	COG1509	lysine 2,3-aminomutase activity
HZ310_09190	COG4479	Belongs to the UPF0346 family
HZ310_09205	COG0671	phosphoesterase, PA-phosphatase related
HZ310_09215	COG0813	purine-nucleoside phosphorylase activity
HZ310_09220	COG1876	peptidase activity
HZ310_09230	COG2226	methyltransferase
HZ310_09235	COG0793	Belongs to the peptidase S41A family
HZ310_09235	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_09240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HZ310_09250	COG0778	Nitroreductase
HZ310_09255	COG1733	regulation of RNA biosynthetic process
HZ310_09270	COG2962	Rard protein
HZ310_09280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HZ310_09285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HZ310_09290	COG0534	Mate efflux family protein
HZ310_09295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HZ310_09300	COG1388	LysM domain
HZ310_09300	COG0791	NLP P60 protein
HZ310_09305	COG2032	superoxide dismutase activity
HZ310_09310	COG0714	Associated with various cellular activities
HZ310_09315	COG4548	von Willebrand factor, type A
HZ310_09320	COG0567	Dehydrogenase, E1 component
HZ310_09325	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZ310_09335	COG0385	Bile acid
HZ310_09340	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HZ310_09345	COG1657	PFAM Prenyltransferase squalene oxidase
HZ310_09350	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_09375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HZ310_09385	COG0514	ATP-dependent DNA helicase (RecQ)
HZ310_09390	COG3584	3D domain protein
HZ310_09390	COG1388	LysM domain
HZ310_09400	COG2322	membrane
HZ310_09405	COG0372	Belongs to the citrate synthase family
HZ310_09410	COG2079	MmgE PrpD family protein
HZ310_09415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HZ310_09420	COG0741	lytic transglycosylase activity
HZ310_09425	COG0531	amino acid
HZ310_09430	COG0640	Transcriptional regulator
HZ310_09440	COG2378	regulation of single-species biofilm formation
HZ310_09445	COG3708	Transcriptional regulator
HZ310_09455	COG1309	transcriptional regulator
HZ310_09475	COG1994	Peptidase M50
HZ310_09480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZ310_09485	COG2211	Major facilitator Superfamily
HZ310_09495	COG1940	carbohydrate kinase activity
HZ310_09500	COG2115	Belongs to the xylose isomerase family
HZ310_09505	COG1070	Carbohydrate kinase
HZ310_09515	COG0243	molybdopterin cofactor binding
HZ310_09530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HZ310_09535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HZ310_09540	COG0454	-acetyltransferase
HZ310_09560	COG0583	DNA-binding transcription factor activity
HZ310_09565	COG0067	glutamate synthase
HZ310_09565	COG0070	glutamate synthase
HZ310_09565	COG0069	glutamate synthase activity
HZ310_09570	COG0493	'glutamate synthase
HZ310_09575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HZ310_09580	COG2146	nitrite reductase [NAD(P)H] activity
HZ310_09585	COG2323	membrane
HZ310_09590	COG4677	pectinesterase activity
HZ310_09595	COG2027	D-alanyl-D-alanine carboxypeptidase
HZ310_09600	COG0534	Mate efflux family protein
HZ310_09620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZ310_09630	COG1587	Uroporphyrinogen-III synthase
HZ310_09635	COG0586	Pfam SNARE associated Golgi protein
HZ310_09645	COG0166	Belongs to the GPI family
HZ310_09665	COG0247	lactate metabolic process
HZ310_09670	COG0277	FAD linked oxidase domain protein
HZ310_09675	COG3835	regulator
HZ310_09685	COG1942	4-Oxalocrotonate Tautomerase
HZ310_09690	COG1349	DNA-binding transcription factor activity
HZ310_09700	COG1649	PFAM Uncharacterised BCR, COG1649
HZ310_09705	COG1960	acyl-CoA dehydrogenase activity
HZ310_09710	COG0318	PFAM AMP-dependent synthetase and ligase
HZ310_09715	COG0439	Biotin carboxylase
HZ310_09720	COG0511	ligase activity, forming carbon-carbon bonds
HZ310_09725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HZ310_09730	COG1024	Enoyl-CoA hydratase
HZ310_09735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HZ310_09740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HZ310_09745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HZ310_09750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HZ310_09755	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_09775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HZ310_09785	COG1105	Belongs to the carbohydrate kinase PfkB family
HZ310_09790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_09790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_09790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_09795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_09795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_09795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_09805	COG2814	Major facilitator Superfamily
HZ310_09810	COG1846	Transcriptional regulator
HZ310_09815	COG5444	nuclease activity
HZ310_09830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_09845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HZ310_09850	COG1609	Transcriptional regulator
HZ310_09855	COG1653	transport
HZ310_09860	COG1175	transmembrane transport
HZ310_09865	COG0395	ABC-type sugar transport system, permease component
HZ310_09870	COG1486	melibiose metabolic process
HZ310_09875	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_09880	COG3507	Belongs to the glycosyl hydrolase 43 family
HZ310_09890	COG0745	RESPONSE REGULATOR receiver
HZ310_09895	COG2205	protein histidine kinase activity
HZ310_09910	COG1263	PTS System
HZ310_09910	COG2190	(PTS) system
HZ310_09910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_09915	COG2723	6-phospho-beta-galactosidase activity
HZ310_09925	COG0657	acetylesterase activity
HZ310_09995	COG0251	oxidation-reduction process
HZ310_10000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HZ310_10010	COG1733	regulation of RNA biosynthetic process
HZ310_10015	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZ310_10020	COG0640	Transcriptional regulator
HZ310_10025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HZ310_10030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HZ310_10035	COG0110	maltose O-acetyltransferase activity
HZ310_10040	COG0738	Major facilitator superfamily
HZ310_10050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HZ310_10055	COG0187	DNA topoisomerase II activity
HZ310_10060	COG1832	CoA-binding protein
HZ310_10065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HZ310_10070	COG4841	protein insertion into membrane
HZ310_10080	COG0824	Thioesterase
HZ310_10100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_10105	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HZ310_10120	COG0071	Belongs to the small heat shock protein (HSP20) family
HZ310_10130	COG4846	Membrane protein involved in cytochrome C biogenesis
HZ310_10135	COG0785	Cytochrome C biogenesis protein
HZ310_10145	COG3763	UPF0154 protein
HZ310_10155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HZ310_10160	COG4224	UPF0291 protein
HZ310_10165	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HZ310_10170	COG1388	LysM domain
HZ310_10175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HZ310_10190	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_10195	COG3209	COG3209 Rhs family protein
HZ310_10200	COG3591	Belongs to the peptidase S1B family
HZ310_10205	COG2124	cytochrome p450
HZ310_10205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HZ310_10210	COG1309	transcriptional regulator
HZ310_10215	COG2323	membrane
HZ310_10235	COG1556	Lactate utilization protein
HZ310_10240	COG1139	Iron-sulfur cluster binding protein
HZ310_10245	COG0247	lactate metabolic process
HZ310_10250	COG0702	epimerase
HZ310_10255	COG1959	2 iron, 2 sulfur cluster binding
HZ310_10265	COG4876	unkown
HZ310_10270	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HZ310_10275	COG3285	dna ligase
HZ310_10275	COG1793	dna ligase
HZ310_10280	COG3619	membrane
HZ310_10290	COG0457	Tetratricopeptide repeat
HZ310_10300	COG5646	InterPro IPR014922
HZ310_10350	COG5444	nuclease activity
HZ310_10365	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_10365	COG5632	N-Acetylmuramoyl-L-alanine amidase
HZ310_10370	COG4824	toxin secretion phage lysis holin
HZ310_10395	COG1705	Flagellar rod assembly protein muramidase FlgJ
HZ310_10470	COG1802	Transcriptional regulator
HZ310_10470	COG4626	Terminase
HZ310_10615	COG4974	Belongs to the 'phage' integrase family
HZ310_10620	COG0174	glutamine synthetase
HZ310_10625	COG0789	Transcriptional regulator
HZ310_10630	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HZ310_10635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HZ310_10640	COG0464	growth
HZ310_10650	COG4112	unkown
HZ310_10655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZ310_10660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HZ310_10665	COG1780	Probably involved in ribonucleotide reductase function
HZ310_10680	COG1923	regulation of RNA biosynthetic process
HZ310_10685	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HZ310_10710	COG2076	Multidrug Resistance protein
HZ310_10715	COG1764	response to oxidative stress
HZ310_10720	COG4195	phage-related replication protein
HZ310_10725	COG1404	Belongs to the peptidase S8 family
HZ310_10730	COG0457	Tetratricopeptide repeat
HZ310_10735	COG4195	phage-related replication protein
HZ310_10740	COG1329	Transcriptional regulator
HZ310_10755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HZ310_10760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HZ310_10770	COG4550	Control of competence regulator ComK, YlbF/YmcA
HZ310_10775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HZ310_10785	COG0156	8-amino-7-oxononanoate synthase activity
HZ310_10790	COG1063	alcohol dehydrogenase
HZ310_10795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZ310_10800	COG2359	stage V sporulation protein S
HZ310_10805	COG1692	metallophosphoesterase
HZ310_10810	COG1418	mRNA catabolic process
HZ310_10815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HZ310_10820	COG1058	Belongs to the CinA family
HZ310_10820	COG1546	Belongs to the CinA family
HZ310_10825	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HZ310_10830	COG1426	Protein conserved in bacteria
HZ310_10845	COG0300	oxidoreductase activity
HZ310_10850	COG1033	growth of symbiont in host cell
HZ310_10850	COG2409	Drug exporters of the RND superfamily
HZ310_10860	COG0612	Peptidase, M16
HZ310_10865	COG0612	Peptidase, M16
HZ310_10870	COG2409	Drug exporters of the RND superfamily
HZ310_10870	COG1033	growth of symbiont in host cell
HZ310_10875	COG2814	Major facilitator Superfamily
HZ310_10880	COG2188	Transcriptional regulator
HZ310_10885	COG1674	ftsk spoiiie
HZ310_10885	COG4980	gas vesicle protein
HZ310_10895	COG0740	serine-type endopeptidase activity
HZ310_10900	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HZ310_10910	COG0527	aspartate kinase activity
HZ310_10915	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HZ310_10920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HZ310_10925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HZ310_10930	COG1873	PFAM PRC-barrel domain
HZ310_10940	COG0612	Peptidase, M16
HZ310_10945	COG0726	polysaccharide deacetylase
HZ310_10950	COG1185	polyribonucleotide nucleotidyltransferase activity
HZ310_10955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HZ310_10960	COG0196	riboflavin kinase activity
HZ310_10965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HZ310_10970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HZ310_10975	COG1550	Protein conserved in bacteria
HZ310_10980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HZ310_10985	COG1358	cellular component organization or biogenesis
HZ310_10990	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HZ310_10995	COG0195	Participates in both transcription termination and antitermination
HZ310_11000	COG0779	Required for maturation of 30S ribosomal subunits
HZ310_11010	COG3693	PFAM glycoside hydrolase, family 10
HZ310_11025	COG2176	DNA-directed DNA polymerase activity
HZ310_11030	COG0442	prolyl-tRNA aminoacylation
HZ310_11035	COG0750	zinc metalloprotease
HZ310_11040	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HZ310_11045	COG4589	Belongs to the CDS family
HZ310_11050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HZ310_11055	COG0233	cytoplasmic translational termination
HZ310_11065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HZ310_11070	COG0052	Belongs to the universal ribosomal protein uS2 family
HZ310_11080	COG1191	sigma factor activity
HZ310_11090	COG1776	CheC inhibitor of MCP methylation
HZ310_11095	COG0835	chemotaxis
HZ310_11100	COG2198	Histidine kinase
HZ310_11100	COG0643	Histidine kinase
HZ310_11105	COG2201	protein-glutamate methylesterase activity
HZ310_11110	COG0455	bacterial-type flagellum organization
HZ310_11115	COG1419	protein localization to endoplasmic reticulum
HZ310_11120	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HZ310_11125	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HZ310_11130	COG1684	flagellar biosynthetic protein fliR
HZ310_11135	COG1987	bacterial-type flagellum assembly
HZ310_11140	COG1338	Plays a role in the flagellum-specific transport system
HZ310_11145	COG3190	flagellar
HZ310_11150	COG2201	protein-glutamate methylesterase activity
HZ310_11155	COG1776	CheC inhibitor of MCP methylation
HZ310_11155	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HZ310_11160	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HZ310_11165	COG1580	Controls the rotational direction of flagella during chemotaxis
HZ310_11170	COG1582	Flagellar protein (FlbD)
HZ310_11175	COG4786	Flagellar basal body rod
HZ310_11180	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HZ310_11185	COG3144	bacterial-type flagellum assembly
HZ310_11195	COG2882	bacterial-type flagellum organization
HZ310_11200	COG1157	protein secretion by the type III secretion system
HZ310_11205	COG1317	bacterial-type flagellum organization
HZ310_11210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HZ310_11215	COG1766	The M ring may be actively involved in energy transduction
HZ310_11220	COG1677	Flagellar hook-basal body complex protein FliE
HZ310_11225	COG1558	bacterial-type flagellum-dependent cell motility
HZ310_11230	COG1815	bacterial-type flagellum-dependent cell motility
HZ310_11235	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HZ310_11240	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HZ310_11245	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HZ310_11250	COG4974	Belongs to the 'phage' integrase family
HZ310_11255	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HZ310_11260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HZ310_11265	COG0758	DNA mediated transformation
HZ310_11270	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HZ310_11275	COG0045	succinate-CoA ligase (ADP-forming) activity
HZ310_11280	COG2257	FlhB HrpN YscU SpaS Family
HZ310_11290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HZ310_11295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HZ310_11300	COG0335	large ribosomal subunit rRNA binding
HZ310_11305	COG0336	Belongs to the RNA methyltransferase TrmD family
HZ310_11310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HZ310_11320	COG1837	Belongs to the UPF0109 family
HZ310_11325	COG0228	four-way junction DNA binding
HZ310_11330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HZ310_11335	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HZ310_11340	COG0552	protein localization to endoplasmic reticulum
HZ310_11345	COG1196	nuclear chromosome segregation
HZ310_11355	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HZ310_11360	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_11365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HZ310_11370	COG0416	fatty acid biosynthetic process
HZ310_11375	COG1349	DNA-binding transcription factor activity
HZ310_11380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HZ310_11385	COG1760	l-serine dehydratase
HZ310_11390	COG1760	l-serine dehydratase
HZ310_11395	COG1461	Dihydroxyacetone kinase
HZ310_11400	COG1302	Protein conserved in bacteria
HZ310_11405	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HZ310_11415	COG1564	THIamine pyrophosphokinase
HZ310_11420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HZ310_11425	COG1162	GTPase activity
HZ310_11430	COG0515	serine threonine protein kinase
HZ310_11430	COG2815	serine threonine protein kinase
HZ310_11435	COG0631	protein serine/threonine phosphatase activity
HZ310_11440	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HZ310_11445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HZ310_11445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HZ310_11450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HZ310_11455	COG0242	peptide deformylase activity
HZ310_11460	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HZ310_11465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HZ310_11470	COG1758	RNA polymerase activity
HZ310_11475	COG0194	GDP metabolic process
HZ310_11480	COG2052	Domain of unknown function (DUF370)
HZ310_11485	COG1561	YicC-like family, N-terminal region
HZ310_11490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HZ310_11500	COG1648	precorrin-2 dehydrogenase activity
HZ310_11505	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
HZ310_11510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HZ310_11515	COG0529	Catalyzes the synthesis of activated sulfate
HZ310_11520	COG2046	Belongs to the sulfate adenylyltransferase family
HZ310_11525	COG0306	phosphate transporter
HZ310_11530	COG0175	sulfate reduction
HZ310_11540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HZ310_11545	COG0284	orotidine-5'-phosphate decarboxylase activity
HZ310_11550	COG0167	dihydroorotate dehydrogenase activity
HZ310_11555	COG0543	2 iron, 2 sulfur cluster binding
HZ310_11560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HZ310_11565	COG0505	Belongs to the CarA family
HZ310_11570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HZ310_11575	COG0540	Belongs to the ATCase OTCase family
HZ310_11580	COG2233	PERMEase
HZ310_11585	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HZ310_11590	COG0564	pseudouridine synthase activity
HZ310_11595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HZ310_11600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HZ310_11605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HZ310_11610	COG3599	regulation of cell shape
HZ310_11615	COG2302	S4 RNA-binding domain
HZ310_11620	COG0762	integral membrane protein
HZ310_11625	COG1799	cell septum assembly
HZ310_11630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HZ310_11640	COG1873	PFAM PRC-barrel domain
HZ310_11645	COG1119	ATPase activity
HZ310_11655	COG3732	PTS system glucitol sorbitol-specific
HZ310_11660	COG3730	PTS system glucitol sorbitol-specific
HZ310_11675	COG2390	Transcriptional regulator
HZ310_11680	COG1191	sigma factor activity
HZ310_11685	COG1191	sigma factor activity
HZ310_11695	COG4412	M6 family metalloprotease domain protein
HZ310_11695	COG1404	Belongs to the peptidase S8 family
HZ310_11700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HZ310_11705	COG0849	cell division
HZ310_11710	COG3856	small basic protein
HZ310_11715	COG3879	Bacterial protein of unknown function (DUF881)
HZ310_11720	COG3879	Bacterial protein of unknown function (DUF881)
HZ310_11725	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HZ310_11730	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HZ310_11735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HZ310_11740	COG0772	Belongs to the SEDS family
HZ310_11745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HZ310_11750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HZ310_11755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HZ310_11760	COG0768	penicillin binding
HZ310_11770	COG4839	cell division protein FtsL
HZ310_11775	COG0275	rRNA processing
HZ310_11780	COG2001	Belongs to the MraZ family
HZ310_11785	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HZ310_11790	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HZ310_11795	COG0454	-acetyltransferase
HZ310_11805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HZ310_11810	COG1399	metal-binding, possibly nucleic acid-binding protein
HZ310_11820	COG3480	Lon protease (S16) C-terminal proteolytic domain
HZ310_11825	COG1752	Esterase of the alpha-beta hydrolase superfamily
HZ310_11830	COG3314	Sporulation integral membrane protein YlbJ
HZ310_11835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HZ310_11840	COG0742	ribosomal rna small subunit methyltransferase
HZ310_11845	COG4471	UPF0298 protein
HZ310_11850	COG3679	Belongs to the UPF0342 family
HZ310_11870	COG2340	Cysteine-rich secretory protein family
HZ310_11875	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
HZ310_11885	COG3336	cytochrome c oxidase
HZ310_11890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HZ310_11895	COG1845	cytochrome c oxidase, subunit III
HZ310_11900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HZ310_11905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HZ310_11905	COG2010	Cytochrome c
HZ310_11910	COG0109	protoheme IX farnesyltransferase activity
HZ310_11915	COG1612	heme a metabolic process
HZ310_11925	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HZ310_11930	COG0772	Belongs to the SEDS family
HZ310_11935	COG4838	Belongs to the UPF0358 family
HZ310_11940	COG2066	Belongs to the glutaminase family
HZ310_11945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HZ310_11950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HZ310_11960	COG4896	Protein conserved in bacteria
HZ310_11985	COG0483	inositol monophosphate 1-phosphatase activity
HZ310_11995	COG4493	Belongs to the UPF0637 family
HZ310_12000	COG4476	Belongs to the UPF0223 family
HZ310_12005	COG1982	Orn Lys Arg decarboxylase major
HZ310_12015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_12020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZ310_12025	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZ310_12030	COG0022	dehydrogenase e1 component
HZ310_12035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HZ310_12050	COG0242	peptide deformylase activity
HZ310_12055	COG0561	phosphatase activity
HZ310_12065	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HZ310_12070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HZ310_12075	COG0569	domain protein
HZ310_12080	COG2105	PFAM AIG2 family protein
HZ310_12080	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
HZ310_12085	COG3852	Histidine kinase
HZ310_12090	COG2002	toxin-antitoxin pair type II binding
HZ310_12095	COG1077	Cell shape determining protein MreB Mrl
HZ310_12105	COG2309	aminopeptidase activity
HZ310_12115	COG0488	(ABC) transporter
HZ310_12125	COG0681	Belongs to the peptidase S26 family
HZ310_12130	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_12130	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_12130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_12135	COG1105	Belongs to the carbohydrate kinase PfkB family
HZ310_12140	COG1349	DNA-binding transcription factor activity
HZ310_12145	COG0577	efflux transmembrane transporter activity
HZ310_12150	COG1136	(ABC) transporter
HZ310_12155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HZ310_12170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HZ310_12175	COG0314	molybdopterin synthase activity
HZ310_12180	COG1763	Mo-molybdopterin cofactor biosynthetic process
HZ310_12185	COG0303	'Molybdopterin
HZ310_12190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HZ310_12195	COG0746	molybdenum cofactor guanylyltransferase activity
HZ310_12210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_12215	COG0450	alkyl hydroperoxide reductase
HZ310_12220	COG0668	transmembrane transport
HZ310_12230	COG1473	amidohydrolase
HZ310_12235	COG2171	N-acyltransferase activity
HZ310_12240	COG0716	FMN binding
HZ310_12250	COG0716	FMN binding
HZ310_12260	COG0583	DNA-binding transcription factor activity
HZ310_12265	COG0517	IMP dehydrogenase activity
HZ310_12275	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
HZ310_12280	COG4703	Protein of unknown function (DUF1797)
HZ310_12285	COG3546	catalase activity
HZ310_12290	COG2200	EAL domain
HZ310_12295	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_12300	COG1408	metallophosphoesterase
HZ310_12305	COG1376	ErfK ybiS ycfS ynhG family protein
HZ310_12310	COG2814	Major facilitator Superfamily
HZ310_12335	COG0835	chemotaxis
HZ310_12335	COG0784	Response regulator, receiver
HZ310_12345	COG1714	RDD family
HZ310_12355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HZ310_12360	COG0436	Aminotransferase
HZ310_12365	COG4191	Histidine kinase
HZ310_12370	COG0768	penicillin binding
HZ310_12375	COG2340	Cysteine-rich secretory protein family
HZ310_12380	COG2084	Dehydrogenase
HZ310_12390	COG0840	transmembrane signaling receptor activity
HZ310_12395	COG1533	DNA photolyase activity
HZ310_12405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HZ310_12410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_12415	COG1263	PTS System
HZ310_12415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_12415	COG2190	(PTS) system
HZ310_12420	COG3711	transcriptional antiterminator
HZ310_12425	COG1609	Transcriptional regulator
HZ310_12435	COG0006	proline dipeptidase activity
HZ310_12440	COG2217	Heavy metal translocating P-type atpase
HZ310_12445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_12450	COG2244	polysaccharide biosynthetic process
HZ310_12455	COG3773	Cell wall hydrolase
HZ310_12465	COG4873	Protein conserved in bacteria
HZ310_12475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HZ310_12480	COG0602	queuosine metabolic process
HZ310_12485	COG0720	synthase
HZ310_12490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HZ310_12495	COG3949	Membrane
HZ310_12500	COG0542	response to heat
HZ310_12505	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HZ310_12510	COG1360	Flagellar Motor Protein
HZ310_12515	COG1846	Transcriptional regulator
HZ310_12520	COG3852	Histidine kinase
HZ310_12530	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HZ310_12535	COG0235	Class ii aldolase
HZ310_12540	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HZ310_12545	COG1850	ribulose-bisphosphate carboxylase activity
HZ310_12550	COG0436	Aminotransferase
HZ310_12555	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HZ310_12560	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HZ310_12565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HZ310_12570	COG5002	protein histidine kinase activity
HZ310_12575	COG3594	Acyltransferase
HZ310_12590	COG2323	membrane
HZ310_12595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HZ310_12600	COG0501	Belongs to the peptidase M48B family
HZ310_12620	COG1191	sigma factor activity
HZ310_12625	COG0861	Integral membrane protein TerC family
HZ310_12630	COG0586	Pfam SNARE associated Golgi protein
HZ310_12635	COG3300	MHYT domain
HZ310_12635	COG5001	Diguanylate cyclase
HZ310_12640	COG1846	Transcriptional regulator
HZ310_12655	COG0789	Transcriptional regulator
HZ310_12670	COG0583	DNA-binding transcription factor activity
HZ310_12680	COG2239	Acts as a magnesium transporter
HZ310_12690	COG3212	peptidase
HZ310_12695	COG3212	peptidase
HZ310_12700	COG3850	Histidine kinase
HZ310_12700	COG5002	protein histidine kinase activity
HZ310_12705	COG0745	RESPONSE REGULATOR receiver
HZ310_12710	COG1404	Belongs to the peptidase S8 family
HZ310_12715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HZ310_12720	COG0590	tRNA wobble adenosine to inosine editing
HZ310_12725	COG1764	response to oxidative stress
HZ310_12730	COG1846	Transcriptional regulator
HZ310_12735	COG1764	response to oxidative stress
HZ310_12745	COG0457	Tetratricopeptide repeat
HZ310_12750	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HZ310_12755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HZ310_12760	COG0788	formyltetrahydrofolate deformylase activity
HZ310_12770	COG2076	Multidrug Resistance protein
HZ310_12775	COG2076	Multidrug Resistance protein
HZ310_12790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZ310_12810	COG1607	acyl-coa hydrolase
HZ310_12815	COG1834	amidinotransferase
HZ310_12820	COG4608	Belongs to the ABC transporter superfamily
HZ310_12825	COG0791	NLP P60 protein
HZ310_12830	COG4948	Mandelate Racemase Muconate Lactonizing
HZ310_12835	COG1619	proteins homologs of microcin C7 resistance protein MccF
HZ310_12840	COG4166	transmembrane transport
HZ310_12845	COG0444	Belongs to the ABC transporter superfamily
HZ310_12850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZ310_12855	COG0601	transmembrane transport
HZ310_12860	COG2362	D-Aminopeptidase
HZ310_12865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HZ310_12870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZ310_12875	COG0346	lactoylglutathione lyase activity
HZ310_12880	COG0531	amino acid
HZ310_12890	COG2390	Transcriptional regulator
HZ310_12895	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_12900	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_12905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZ310_12910	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZ310_12915	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZ310_12915	COG0022	dehydrogenase e1 component
HZ310_12920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HZ310_12940	COG3775	system Galactitol-specific IIC component
HZ310_12950	COG0405	Gamma-glutamyltransferase
HZ310_12960	COG1392	Phosphate transport regulator
HZ310_12965	COG0306	phosphate transporter
HZ310_12980	COG5632	N-Acetylmuramoyl-L-alanine amidase
HZ310_12980	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_12985	COG2856	Zn peptidase
HZ310_12990	COG4195	phage-related replication protein
HZ310_13020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZ310_13025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZ310_13030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZ310_13035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HZ310_13045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HZ310_13065	COG0457	Tetratricopeptide repeat
HZ310_13090	COG2807	transmembrane transport
HZ310_13095	COG0583	DNA-binding transcription factor activity
HZ310_13110	COG0583	DNA-binding transcription factor activity
HZ310_13115	COG3173	Aminoglycoside phosphotransferase
HZ310_13190	COG5632	N-Acetylmuramoyl-L-alanine amidase
HZ310_13190	COG3409	Peptidoglycan-binding domain 1 protein
HZ310_13225	COG3778	Protein conserved in bacteria
HZ310_13230	COG3299	homolog of phage Mu protein gp47
HZ310_13235	COG3628	GPW Gp25 family protein
HZ310_13245	COG4193	domain, Protein
HZ310_13250	COG1652	LysM domain
HZ310_13255	COG3953	SLT domain
HZ310_13255	COG5280	Phage tail tape measure protein TP901
HZ310_13255	COG3953	SLT domain
HZ310_13255	COG5280	Phage tail tape measure protein TP901
HZ310_13315	COG4653	Phage capsid family
HZ310_13320	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HZ310_13330	COG2369	cell adhesion
HZ310_13335	COG5518	Phage portal protein
HZ310_13340	COG1783	phage Terminase large subunit
HZ310_13395	COG4282	regulation of fungal-type cell wall biogenesis
HZ310_13430	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HZ310_13440	COG0305	Participates in initiation and elongation during chromosome replication
HZ310_13500	COG1396	sequence-specific DNA binding
HZ310_13510	COG2856	Zn peptidase
HZ310_13515	COG0582	viral genome integration into host DNA
HZ310_13525	COG0626	cystathionine gamma-synthase activity
HZ310_13530	COG0626	cystathionine gamma-synthase activity
HZ310_13535	COG2382	esterase
HZ310_13540	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HZ310_13545	COG2153	protein acetylation
HZ310_13555	COG0210	DNA helicase
HZ310_13615	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HZ310_13620	COG0351	phosphomethylpyrimidine kinase
HZ310_13625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HZ310_13630	COG2022	thiamine diphosphate biosynthetic process
HZ310_13635	COG2104	thiamine diphosphate biosynthetic process
HZ310_13645	COG0352	thiamine-phosphate diphosphorylase activity
HZ310_13650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HZ310_13655	COG0569	domain protein
HZ310_13655	COG0475	glutathione-regulated potassium exporter activity
HZ310_13660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HZ310_13665	COG0564	pseudouridine synthase activity
HZ310_13670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HZ310_13675	COG2357	RelA SpoT domain protein
HZ310_13685	COG4116	CYTH
HZ310_13690	COG0741	lytic transglycosylase activity
HZ310_13695	COG2346	COG2346, Truncated hemoglobins
HZ310_13705	COG1164	Oligoendopeptidase f
HZ310_13715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HZ310_13720	COG4862	establishment of competence for transformation
HZ310_13725	COG0861	Integral membrane protein TerC family
HZ310_13730	COG1393	Belongs to the ArsC family
HZ310_13735	COG0456	acetyltransferase
HZ310_13745	COG4608	Belongs to the ABC transporter superfamily
HZ310_13750	COG0444	Belongs to the ABC transporter superfamily
HZ310_13755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZ310_13760	COG0601	transmembrane transport
HZ310_13765	COG4166	transmembrane transport
HZ310_13770	COG0180	Tryptophanyl-tRNA synthetase
HZ310_13790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HZ310_13795	COG0601	transmembrane transport
HZ310_13805	COG4608	Belongs to the ABC transporter superfamily
HZ310_13810	COG0444	Belongs to the ABC transporter superfamily
HZ310_13815	COG5504	Zn-dependent protease
HZ310_13820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HZ310_13825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HZ310_13840	COG1744	ABC transporter substrate-binding protein PnrA-like
HZ310_13850	COG2267	carboxylic ester hydrolase activity
HZ310_13860	COG2814	Major facilitator Superfamily
HZ310_13870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HZ310_13875	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HZ310_13880	COG0505	Belongs to the CarA family
HZ310_13885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HZ310_13890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HZ310_13895	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HZ310_13900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HZ310_13915	COG2151	metal-sulfur cluster biosynthetic enzyme
HZ310_13920	COG1073	alpha beta
HZ310_13925	COG0561	phosphatase activity
HZ310_13945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZ310_13950	COG1307	EDD domain protein, DegV family
HZ310_13955	COG0840	transmembrane signaling receptor activity
HZ310_13965	COG2996	Protein conserved in bacteria
HZ310_13970	COG1666	GTP binding
HZ310_13975	COG0646	methionine synthase
HZ310_13975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HZ310_13980	COG0646	methionine synthase
HZ310_13980	COG1410	methionine synthase
HZ310_14010	COG0076	glutamate decarboxylase activity
HZ310_14040	COG1917	Cupin 2, conserved barrel domain protein
HZ310_14040	COG2207	Transcriptional regulator
HZ310_14045	COG0534	Mate efflux family protein
HZ310_14050	COG1562	ergosterol biosynthetic process
HZ310_14065	COG0367	asparagine synthase
HZ310_14080	COG0179	Fumarylacetoacetate (FAA) hydrolase
HZ310_14085	COG5337	Spore coat protein CotH
HZ310_14125	COG1403	HNH endonuclease
HZ310_14130	COG0419	ATPase involved in DNA repair
HZ310_14135	COG0420	3'-5' exonuclease activity
HZ310_14140	COG1074	ATP-dependent DNA helicase activity
HZ310_14145	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HZ310_14150	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HZ310_14155	COG2259	Doxx family
HZ310_14160	COG0501	Belongs to the peptidase M48B family
HZ310_14170	COG3180	Ammonia monooxygenase
HZ310_14175	COG0681	Belongs to the peptidase S26 family
HZ310_14180	COG0398	Pfam SNARE associated Golgi protein
HZ310_14190	COG1316	TRANSCRIPTIONal
HZ310_14195	COG2732	(Barnase) inhibitor
HZ310_14220	COG4903	ComK protein
HZ310_14230	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_14235	COG0723	plastoquinol--plastocyanin reductase activity
HZ310_14235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HZ310_14240	COG0840	transmembrane signaling receptor activity
HZ310_14245	COG0406	alpha-ribazole phosphatase activity
HZ310_14250	COG1404	Belongs to the peptidase S8 family
HZ310_14255	COG0501	Belongs to the peptidase M48B family
HZ310_14265	COG0318	PFAM AMP-dependent synthetase and ligase
HZ310_14270	COG0095	Lipoate-protein ligase
HZ310_14275	COG1234	tRNA 3'-trailer cleavage
HZ310_14285	COG1301	dicarboxylic acid transport
HZ310_14290	COG1363	Peptidase, m42
HZ310_14295	COG1511	domain protein
HZ310_14300	COG1309	transcriptional regulator
HZ310_14315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HZ310_14320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HZ310_14325	COG2329	Antibiotic biosynthesis monooxygenase
HZ310_14335	COG1473	amidohydrolase
HZ310_14345	COG4473	ABC transporter
HZ310_14350	COG1131	(ABC) transporter
HZ310_14355	COG0537	adenosine 5'-monophosphoramidase activity
HZ310_14360	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HZ310_14375	COG4980	gas vesicle protein
HZ310_14380	COG1846	Transcriptional regulator
HZ310_14405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HZ310_14415	COG3481	metal-dependent phosphohydrolase, HD sub domain
HZ310_14420	COG4717	serine-type aminopeptidase activity
HZ310_14425	COG0420	3'-5' exonuclease activity
HZ310_14435	COG1024	Enoyl-CoA hydratase
HZ310_14445	COG0490	domain, Protein
HZ310_14450	COG0475	glutathione-regulated potassium exporter activity
HZ310_14465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HZ310_14470	COG0561	phosphatase activity
HZ310_14475	COG3679	Belongs to the UPF0342 family
HZ310_14480	COG4399	Belongs to the UPF0754 family
HZ310_14485	COG0189	ligase activity
HZ310_14490	COG0189	ligase activity
HZ310_14500	COG2508	Transcriptional regulator
HZ310_14505	COG3842	ATPase activity
HZ310_14515	COG0702	epimerase
HZ310_14520	COG1132	(ABC) transporter
HZ310_14525	COG1132	(ABC) transporter
HZ310_14530	COG0589	response to stress
HZ310_14535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HZ310_14540	COG0726	polysaccharide deacetylase
HZ310_14545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HZ310_14550	COG0668	transmembrane transport
HZ310_14560	COG0584	glycerophosphoryl diester phosphodiesterase
HZ310_14565	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HZ310_14580	COG1253	flavin adenine dinucleotide binding
HZ310_14585	COG0789	Transcriptional regulator
HZ310_14590	COG1253	flavin adenine dinucleotide binding
HZ310_14595	COG0204	Acyl-transferase
HZ310_14600	COG1595	DNA-templated transcription, initiation
HZ310_14615	COG1388	LysM domain
HZ310_14615	COG0791	NLP P60 protein
HZ310_14620	COG1785	Belongs to the alkaline phosphatase family
HZ310_14625	COG2719	SpoVR family
HZ310_14630	COG1017	nitric oxide dioxygenase activity
HZ310_14630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HZ310_14635	COG1959	2 iron, 2 sulfur cluster binding
HZ310_14640	COG0753	catalase activity
HZ310_14660	COG2197	response regulator
HZ310_14665	COG2203	Gaf domain
HZ310_14665	COG4585	Histidine kinase
HZ310_14670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HZ310_14675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HZ310_14680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HZ310_14685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HZ310_14690	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HZ310_14695	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HZ310_14700	COG3835	regulator
HZ310_14715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HZ310_14715	COG3153	acetyltransferase
HZ310_14720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HZ310_14730	COG0564	pseudouridine synthase activity
HZ310_14735	COG3764	Sortase (surface protein transpeptidase)
HZ310_14740	COG1525	nuclease
HZ310_14740	COG4085	toxin activity
HZ310_14740	COG0737	Belongs to the 5'-nucleotidase family
HZ310_14745	COG5002	protein histidine kinase activity
HZ310_14750	COG5577	PFAM Coat F domain
HZ310_14775	COG3706	GGDEF domain
HZ310_14780	COG1278	Cold shock
HZ310_14790	COG0655	NAD(P)H dehydrogenase (quinone) activity
HZ310_14795	COG2814	Major facilitator Superfamily
HZ310_14800	COG1566	PFAM secretion protein HlyD family protein
HZ310_14805	COG2718	Belongs to the UPF0229 family
HZ310_14810	COG2766	serine protein kinase
HZ310_14820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HZ310_14830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HZ310_14835	COG3382	B3 4 domain protein
HZ310_14865	COG1131	(ABC) transporter
HZ310_14875	COG2873	o-acetylhomoserine
HZ310_14880	COG0681	Belongs to the peptidase S26 family
HZ310_14885	COG1368	sulfuric ester hydrolase activity
HZ310_15030	COG0735	belongs to the Fur family
HZ310_15035	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HZ310_15040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HZ310_15045	COG4129	membrane
HZ310_15065	COG4608	Belongs to the ABC transporter superfamily
HZ310_15070	COG0444	Belongs to the ABC transporter superfamily
HZ310_15075	COG1132	(ABC) transporter
HZ310_15080	COG3557	Belongs to the UPF0374 family
HZ310_15100	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_15110	COG1194	a g-specific adenine glycosylase
HZ310_15115	COG1988	membrane-bound metal-dependent
HZ310_15125	COG1191	sigma factor activity
HZ310_15135	COG2140	Oxalate decarboxylase
HZ310_15150	COG4485	Bacterial membrane protein, YfhO
HZ310_15155	COG0463	Glycosyl transferase, family 2
HZ310_15180	COG2137	regulation of response to DNA damage stimulus
HZ310_15185	COG1090	epimerase
HZ310_15205	COG0778	Nitroreductase
HZ310_15225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HZ310_15225	COG0392	lysyltransferase activity
HZ310_15230	COG1846	Transcriptional regulator
HZ310_15240	COG2318	DinB family
HZ310_15260	COG1595	DNA-templated transcription, initiation
HZ310_15265	COG1742	UPF0060 membrane protein
HZ310_15270	COG1132	(ABC) transporter
HZ310_15275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_15280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_15280	COG2207	Transcriptional regulator
HZ310_15285	COG0492	ferredoxin-NADP+ reductase activity
HZ310_15290	COG2755	lipolytic protein G-D-S-L family
HZ310_15295	COG4637	Psort location Cytoplasmic, score
HZ310_15305	COG1309	transcriptional regulator
HZ310_15310	COG2076	Multidrug Resistance protein
HZ310_15315	COG2076	Multidrug Resistance protein
HZ310_15355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HZ310_15370	COG2814	Major facilitator Superfamily
HZ310_15375	COG0789	Transcriptional regulator
HZ310_15395	COG1309	transcriptional regulator
HZ310_15400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HZ310_15405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HZ310_15415	COG0598	Magnesium transport protein CorA
HZ310_15425	COG0726	polysaccharide deacetylase
HZ310_15435	COG0535	radical SAM domain protein
HZ310_15440	COG0668	transmembrane transport
HZ310_15450	COG0217	transcriptional regulatory protein
HZ310_15460	COG0387	Pfam Sodium calcium exchanger
HZ310_15470	COG0477	Major facilitator Superfamily
HZ310_15475	COG1295	ribonuclease BN
HZ310_15480	COG4980	gas vesicle protein
HZ310_15485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HZ310_15490	COG1115	amino acid carrier protein
HZ310_15495	COG4840	Belongs to the UPF0435 family
HZ310_15500	COG0693	protein deglycase activity
HZ310_15505	COG0737	Belongs to the 5'-nucleotidase family
HZ310_15515	COG2188	Transcriptional regulator
HZ310_15520	COG0366	Alpha amylase catalytic
HZ310_15525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_15525	COG1263	PTS System
HZ310_15540	COG0076	glutamate decarboxylase activity
HZ310_15545	COG1368	sulfuric ester hydrolase activity
HZ310_15560	COG3739	integral membrane protein
HZ310_15565	COG1263	PTS System
HZ310_15565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_15570	COG0024	Methionine aminopeptidase
HZ310_15585	COG2258	MOSC domain
HZ310_15590	COG1254	Belongs to the acylphosphatase family
HZ310_15595	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HZ310_15600	COG1695	Transcriptional regulator
HZ310_15605	COG3479	Phenolic acid decarboxylase
HZ310_15615	COG2851	Citrate transporter
HZ310_15620	COG3181	Tripartite tricarboxylate transporter family receptor
HZ310_15625	COG4565	transcriptional regulatory protein
HZ310_15630	COG3290	protein histidine kinase activity
HZ310_15640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZ310_15640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HZ310_15650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HZ310_15655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZ310_15655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HZ310_15675	COG2130	NADP-dependent
HZ310_15680	COG0513	Belongs to the DEAD box helicase family
HZ310_15685	COG0488	(ABC) transporter
HZ310_15695	COG0789	Transcriptional regulator
HZ310_15700	COG0488	(ABC) transporter
HZ310_15705	COG0457	Tetratricopeptide repeat
HZ310_15705	COG0463	Glycosyl transferase, family 2
HZ310_15710	COG0531	amino acid
HZ310_15725	COG0071	Belongs to the small heat shock protein (HSP20) family
HZ310_15740	COG0471	metal ion transport
HZ310_15750	COG2223	nitrite transmembrane transporter activity
HZ310_15755	COG1442	glycosyl transferase family 8
HZ310_15760	COG1216	Glycosyl transferase, family 2
HZ310_15765	COG1442	glycosyl transferase family 8
HZ310_15770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HZ310_15775	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HZ310_15805	COG2211	Major facilitator Superfamily
HZ310_15815	COG1486	melibiose metabolic process
HZ310_15830	COG0492	ferredoxin-NADP+ reductase activity
HZ310_15835	COG1959	2 iron, 2 sulfur cluster binding
HZ310_15845	COG1486	melibiose metabolic process
HZ310_15850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_15850	COG1263	PTS System
HZ310_15855	COG1737	Transcriptional regulator
HZ310_15865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HZ310_15880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HZ310_15885	COG1597	lipid kinase activity
HZ310_15890	COG1957	nucleoside hydrolase
HZ310_15895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HZ310_15900	COG1309	transcriptional regulator
HZ310_15905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HZ310_15910	COG0154	amidase activity
HZ310_15915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HZ310_15920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HZ310_15925	COG1285	pathogenesis
HZ310_15930	COG1785	Belongs to the alkaline phosphatase family
HZ310_15935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HZ310_15945	COG4221	oxidoreductase activity
HZ310_15945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HZ310_15945	COG3321	synthase
HZ310_15945	COG0300	oxidoreductase activity
HZ310_15955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZ310_15965	COG1960	acyl-CoA dehydrogenase activity
HZ310_15980	COG1250	3-hydroxyacyl-CoA dehydrogenase
HZ310_15995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HZ310_16010	COG4851	CamS sex pheromone cAM373 precursor
HZ310_16015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HZ310_16020	COG0210	DNA helicase
HZ310_16025	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HZ310_16040	COG0069	glutamate synthase activity
HZ310_16050	COG4496	protein, YerC YecD
HZ310_16055	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HZ310_16065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HZ310_16070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HZ310_16075	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HZ310_16080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HZ310_16095	COG0151	Belongs to the GarS family
HZ310_16100	COG0138	bifunctional purine biosynthesis protein purh
HZ310_16105	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HZ310_16110	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HZ310_16115	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HZ310_16120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HZ310_16125	COG0047	phosphoribosylformylglycinamidine synthase activity
HZ310_16130	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HZ310_16135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HZ310_16140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HZ310_16145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HZ310_16150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HZ310_16160	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
HZ310_16165	COG3064	Membrane
HZ310_16170	COG2252	PERMEase
HZ310_16175	COG0583	DNA-binding transcription factor activity
HZ310_16180	COG2814	Major facilitator Superfamily
HZ310_16195	COG1595	DNA-templated transcription, initiation
HZ310_16225	COG1522	sequence-specific DNA binding
HZ310_16235	COG2207	Transcriptional regulator
HZ310_16245	COG0519	Catalyzes the synthesis of GMP from XMP
HZ310_16245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HZ310_16250	COG1305	Transglutaminase-like
HZ310_16255	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
HZ310_16260	COG0714	Associated with various cellular activities
HZ310_16265	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HZ310_16270	COG1113	amino acid transport
HZ310_16275	COG2132	Multicopper oxidase
HZ310_16285	COG0823	Involved in the tonB-independent uptake of proteins
HZ310_16290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HZ310_16315	COG0459	protein refolding
HZ310_16320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HZ310_16325	COG1266	CAAX protease self-immunity
HZ310_16340	COG0805	protein transport
HZ310_16345	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HZ310_16350	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HZ310_16355	COG0315	cyclic pyranopterin monophosphate synthase activity
HZ310_16360	COG0488	(ABC) transporter
HZ310_16365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HZ310_16370	COG0456	acetyltransferase
HZ310_16375	COG1214	PFAM Peptidase M22, glycoprotease
HZ310_16380	COG0802	atpase or kinase
HZ310_16385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HZ310_16425	COG1301	dicarboxylic acid transport
HZ310_16435	COG0697	spore germination
HZ310_16440	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HZ310_16450	COG4122	O-methyltransferase activity
HZ310_16460	COG0667	Aldo Keto reductase
HZ310_16465	COG0583	DNA-binding transcription factor activity
HZ310_16470	COG0456	acetyltransferase
HZ310_16480	COG1396	sequence-specific DNA binding
HZ310_16495	COG0778	Nitroreductase
HZ310_16500	COG1846	Transcriptional regulator
HZ310_16505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HZ310_16510	COG1309	transcriptional regulator
HZ310_16545	COG2197	response regulator
HZ310_16550	COG4585	Histidine kinase
HZ310_16555	COG2409	Drug exporters of the RND superfamily
HZ310_16560	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HZ310_16565	COG2814	Major facilitator Superfamily
HZ310_16585	COG0252	asparaginase activity
HZ310_16610	COG0583	DNA-binding transcription factor activity
HZ310_16630	COG0477	Major facilitator Superfamily
HZ310_16645	COG0789	Transcriptional regulator
HZ310_16650	COG1064	alcohol dehydrogenase
HZ310_16655	COG1329	Transcriptional regulator
HZ310_16660	COG1278	Cold shock
HZ310_16665	COG0456	acetyltransferase
HZ310_16665	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HZ310_16680	COG0604	alcohol dehydrogenase
HZ310_16725	COG3284	Transcriptional regulator
HZ310_16730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HZ310_16735	COG0508	dehydrogenase complex catalyzes the overall conversion of
HZ310_16740	COG0022	dehydrogenase e1 component
HZ310_16745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HZ310_16750	COG3091	SprT-like family
HZ310_16760	COG2183	response to ionizing radiation
HZ310_16765	COG2208	phosphoserine phosphatase activity
HZ310_16770	COG1191	sigma factor activity
HZ310_16775	COG2172	sigma factor antagonist activity
HZ310_16780	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_16785	COG2208	phosphoserine phosphatase activity
HZ310_16790	COG2172	sigma factor antagonist activity
HZ310_16795	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_16800	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_16805	COG2337	Toxic component of a toxin-antitoxin (TA) module
HZ310_16810	COG0864	Transcriptional regulator
HZ310_16815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HZ310_16820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HZ310_16825	COG0736	holo-[acyl-carrier-protein] synthase activity
HZ310_16830	COG0705	Rhomboid family
HZ310_16835	COG3428	Bacterial PH domain
HZ310_16840	COG3402	PFAM membrane-flanked domain
HZ310_16845	COG0513	Belongs to the DEAD box helicase family
HZ310_16860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HZ310_16865	COG1181	Belongs to the D-alanine--D-alanine ligase family
HZ310_16870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_16885	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
HZ310_16890	COG1131	(ABC) transporter
HZ310_16900	COG1301	dicarboxylic acid transport
HZ310_16905	COG0628	permease
HZ310_16910	COG1301	dicarboxylic acid transport
HZ310_16915	COG4565	transcriptional regulatory protein
HZ310_16920	COG3290	protein histidine kinase activity
HZ310_16925	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HZ310_16930	COG2217	Heavy metal translocating P-type atpase
HZ310_16935	COG2261	transglycosylase associated protein
HZ310_16940	COG1914	H( )-stimulated, divalent metal cation uptake system
HZ310_16945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZ310_16965	COG5444	nuclease activity
HZ310_16970	COG0028	Belongs to the TPP enzyme family
HZ310_16975	COG0531	amino acid
HZ310_16985	COG1215	transferase activity, transferring glycosyl groups
HZ310_16990	COG5298	Protein conserved in bacteria
HZ310_16995	COG3706	GGDEF domain
HZ310_17000	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HZ310_17005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HZ310_17005	COG0551	DNA topoisomerase type I activity
HZ310_17015	COG0473	3-isopropylmalate dehydrogenase activity
HZ310_17020	COG0697	spore germination
HZ310_17025	COG2207	Transcriptional regulator
HZ310_17025	COG1917	Cupin 2, conserved barrel domain protein
HZ310_17030	COG1802	Transcriptional regulator
HZ310_17035	COG2814	Major facilitator Superfamily
HZ310_17055	COG3871	stress protein (general stress protein 26)
HZ310_17060	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_17065	COG2226	methyltransferase
HZ310_17070	COG3711	transcriptional antiterminator
HZ310_17080	COG2755	lipolytic protein G-D-S-L family
HZ310_17085	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HZ310_17090	COG1414	Transcriptional regulator
HZ310_17095	COG1984	allophanate hydrolase subunit 2
HZ310_17100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HZ310_17105	COG4336	lyase activity
HZ310_17110	COG1914	H( )-stimulated, divalent metal cation uptake system
HZ310_17115	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
HZ310_17120	COG0457	Tetratricopeptide repeat
HZ310_17145	COG0561	phosphatase activity
HZ310_17155	COG0346	lactoylglutathione lyase activity
HZ310_17175	COG0840	transmembrane signaling receptor activity
HZ310_17180	COG0246	Mannitol dehydrogenase
HZ310_17185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_17190	COG2213	PTS system mannitol-specific
HZ310_17195	COG2372	response to copper ion
HZ310_17195	COG1276	copper resistance
HZ310_17200	COG4549	nuclear export factor GLE1
HZ310_17205	COG2249	NAD(P)H dehydrogenase (quinone) activity
HZ310_17210	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_17215	COG0531	amino acid
HZ310_17220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HZ310_17225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZ310_17230	COG0640	Transcriptional regulator
HZ310_17240	COG1309	transcriptional regulator
HZ310_17245	COG2814	Major facilitator Superfamily
HZ310_17250	COG0527	aspartate kinase activity
HZ310_17255	COG1366	Belongs to the anti-sigma-factor antagonist family
HZ310_17260	COG3850	Histidine kinase
HZ310_17260	COG5002	protein histidine kinase activity
HZ310_17265	COG0745	RESPONSE REGULATOR receiver
HZ310_17270	COG2079	MmgE PrpD family protein
HZ310_17275	COG1473	amidohydrolase
HZ310_17280	COG1126	abc transporter atp-binding protein
HZ310_17285	COG0765	amino acid transport
HZ310_17290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_17295	COG0456	acetyltransferase
HZ310_17300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZ310_17305	COG5434	Belongs to the glycosyl hydrolase 28 family
HZ310_17310	COG3104	oligopeptide transport
HZ310_17315	COG0833	amino acid
HZ310_17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_17325	COG0765	amino acid transport
HZ310_17330	COG1126	abc transporter atp-binding protein
HZ310_17335	COG2364	Membrane
HZ310_17350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZ310_17355	COG0697	spore germination
HZ310_17360	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HZ310_17375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZ310_17380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZ310_17385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZ310_17395	COG1176	ABC-type spermidine putrescine transport system, permease component I
HZ310_17400	COG3842	ATPase activity
HZ310_17420	COG3209	COG3209 Rhs family protein
HZ310_17425	COG0840	transmembrane signaling receptor activity
HZ310_17425	COG3290	protein histidine kinase activity
HZ310_17435	COG2746	aminoglycoside 3-N-acetyltransferase activity
HZ310_17440	COG1522	sequence-specific DNA binding
HZ310_17445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HZ310_17455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HZ310_17460	COG0765	amino acid transport
HZ310_17465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HZ310_17470	COG2508	Transcriptional regulator
HZ310_17475	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_17480	COG0506	proline dehydrogenase activity
HZ310_17485	COG3541	Predicted nucleotidyltransferase
HZ310_17495	COG3458	cephalosporin-C deacetylase activity
HZ310_17500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HZ310_17505	COG0583	DNA-binding transcription factor activity
HZ310_17510	COG2226	methyltransferase
HZ310_17515	COG0477	Major facilitator Superfamily
HZ310_17525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HZ310_17530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HZ310_17545	COG2271	Major facilitator Superfamily
HZ310_17550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HZ310_17560	COG0028	Belongs to the TPP enzyme family
HZ310_17565	COG0710	3-dehydroquinate dehydratase activity
HZ310_17570	COG1012	belongs to the aldehyde dehydrogenase family
HZ310_17585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HZ310_17590	COG3665	Urea carboxylase-associated protein
HZ310_17595	COG1113	amino acid transport
HZ310_17600	COG3403	YqcI/YcgG family
HZ310_17610	COG1280	lysine exporter protein (LysE YggA)
HZ310_17615	COG0738	Major facilitator superfamily
HZ310_17620	COG0673	inositol 2-dehydrogenase activity
HZ310_17625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HZ310_17630	COG1609	Transcriptional regulator
HZ310_17635	COG1620	l-lactate permease
HZ310_17640	COG0039	L-malate dehydrogenase activity
HZ310_17645	COG1288	antiporter activity
HZ310_17650	COG1473	amidohydrolase
HZ310_17665	COG2113	Glycine betaine
HZ310_17670	COG4176	ABC-type proline glycine betaine transport system permease component
HZ310_17675	COG4175	Glycine betaine
HZ310_17675	COG0517	IMP dehydrogenase activity
HZ310_17680	COG3853	Toxic anion resistance protein (TelA)
HZ310_17710	COG0861	Integral membrane protein TerC family
HZ310_17715	COG2310	stress, protein
HZ310_17720	COG2310	stress, protein
HZ310_17725	COG2310	stress, protein
HZ310_17730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HZ310_17740	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_17745	COG3773	Cell wall hydrolase
HZ310_17760	COG1668	transmembrane transport
HZ310_17765	COG4555	ABC transporter
HZ310_17770	COG3279	Response regulator of the LytR AlgR family
HZ310_17775	COG3290	protein histidine kinase activity
HZ310_17780	COG0667	Aldo Keto reductase
HZ310_17790	COG1405	negative regulation of cell septum assembly
HZ310_17790	COG3012	SEC-C Motif Domain Protein
HZ310_17795	COG0784	Response regulator, receiver
HZ310_17800	COG4191	Histidine kinase
HZ310_17805	COG2066	Belongs to the glutaminase family
HZ310_17810	COG1115	amino acid carrier protein
HZ310_17815	COG0596	Alpha beta hydrolase
HZ310_17825	COG0531	amino acid
HZ310_17830	COG0318	PFAM AMP-dependent synthetase and ligase
HZ310_17835	COG1846	Transcriptional regulator
HZ310_17840	COG1063	alcohol dehydrogenase
HZ310_17845	COG1917	Cupin 2, conserved barrel domain protein
HZ310_17850	COG1309	transcriptional regulator
HZ310_17860	COG1404	Belongs to the peptidase S8 family
HZ310_17875	COG0456	acetyltransferase
HZ310_17880	COG2814	Major facilitator Superfamily
HZ310_17895	COG1695	Transcriptional regulator
HZ310_17900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HZ310_17905	COG2040	homocysteine
HZ310_17910	COG0833	amino acid
HZ310_17925	COG1404	Belongs to the peptidase S8 family
HZ310_17935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_17940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HZ310_17945	COG0383	alpha-mannosidase activity
HZ310_17950	COG1940	carbohydrate kinase activity
HZ310_17955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HZ310_17955	COG3711	transcriptional antiterminator
HZ310_17980	COG2723	6-phospho-beta-galactosidase activity
HZ310_17985	COG2190	(PTS) system
HZ310_17985	COG1263	PTS System
HZ310_17985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_17990	COG3711	transcriptional antiterminator
HZ310_18000	COG0531	amino acid
HZ310_18010	COG0371	Dehydrogenase
HZ310_18015	COG0656	L-ascorbic acid biosynthetic process
HZ310_18025	COG1683	Conserved Protein
HZ310_18035	COG1846	Transcriptional regulator
HZ310_18045	COG2814	Major facilitator Superfamily
HZ310_18050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HZ310_18060	COG0730	response to heat
HZ310_18065	COG0425	Belongs to the sulfur carrier protein TusA family
HZ310_18070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HZ310_18070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZ310_18075	COG0425	Belongs to the sulfur carrier protein TusA family
HZ310_18075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZ310_18080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HZ310_18085	COG2210	Belongs to the sulfur carrier protein TusA family
HZ310_18090	COG1937	Protein conserved in bacteria
HZ310_18100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HZ310_18105	COG1331	Highly conserved protein containing a thioredoxin domain
HZ310_18115	COG2271	Major facilitator Superfamily
HZ310_18120	COG0584	glycerophosphoryl diester phosphodiesterase
HZ310_18125	COG1113	amino acid transport
HZ310_18140	COG1309	transcriptional regulator
HZ310_18145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HZ310_18155	COG1476	TRANSCRIPTIONal
HZ310_18175	COG2311	Membrane
HZ310_18185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_18190	COG1413	lyase activity
HZ310_18200	COG1131	(ABC) transporter
HZ310_18205	COG1266	CAAX protease self-immunity
HZ310_18210	COG0535	radical SAM domain protein
HZ310_18230	COG1131	(ABC) transporter
HZ310_18250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HZ310_18255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HZ310_18260	COG4856	YbbR-like protein
HZ310_18265	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HZ310_18270	COG5662	AntiSigma factor
HZ310_18275	COG1595	DNA-templated transcription, initiation
HZ310_18310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HZ310_18315	COG1737	Transcriptional regulator
HZ310_18320	COG1263	PTS System
HZ310_18320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HZ310_18325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HZ310_18330	COG1472	Belongs to the glycosyl hydrolase 3 family
HZ310_18335	COG3876	Protein conserved in bacteria
HZ310_18340	COG0385	Bile acid
HZ310_18345	COG0659	secondary active sulfate transmembrane transporter activity
HZ310_18375	COG0726	polysaccharide deacetylase
HZ310_18380	COG2194	sulfuric ester hydrolase activity
HZ310_18390	COG0489	protein tyrosine kinase activity
HZ310_18395	COG0860	N-Acetylmuramoyl-L-alanine amidase
HZ310_18425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HZ310_18430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HZ310_18435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HZ310_18440	COG0101	tRNA pseudouridine synthase activity
HZ310_18445	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HZ310_18450	COG1122	ATPase activity
HZ310_18455	COG1122	ATPase activity
HZ310_18460	COG0203	ribosomal protein L17
HZ310_18465	COG0202	RNA polymerase activity
HZ310_18470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HZ310_18475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HZ310_18480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HZ310_18485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HZ310_18490	COG0024	Methionine aminopeptidase
HZ310_18495	COG0563	adenylate kinase activity
HZ310_18500	COG0201	protein transport
HZ310_18505	COG0200	Binds to the 23S rRNA
HZ310_18510	COG1841	ribosomal large subunit assembly
HZ310_18515	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HZ310_18520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HZ310_18525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HZ310_18530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HZ310_18535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HZ310_18540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HZ310_18545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HZ310_18550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HZ310_18555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HZ310_18560	COG0255	Belongs to the universal ribosomal protein uL29 family
HZ310_18570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HZ310_18575	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HZ310_18580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HZ310_18585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HZ310_18590	COG0089	rRNA binding
HZ310_18595	COG0088	Forms part of the polypeptide exit tunnel
HZ310_18600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HZ310_18610	COG0596	Alpha beta hydrolase
HZ310_18615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HZ310_18620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HZ310_18625	COG0049	tRNA binding
HZ310_18630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HZ310_18635	COG1358	cellular component organization or biogenesis
HZ310_18640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HZ310_18645	COG0085	RNA polymerase activity
HZ310_18650	COG2813	Specifically methylates the guanine in position
HZ310_18655	COG0222	ribosome binding
HZ310_18660	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HZ310_18665	COG0081	regulation of translation
HZ310_18675	COG0250	Participates in transcription elongation, termination and antitermination
HZ310_18680	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HZ310_18685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HZ310_18690	COG1595	DNA-templated transcription, initiation
HZ310_18695	COG3688	RNA-binding protein containing a PIN domain
HZ310_18700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HZ310_18705	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HZ310_18710	COG0215	cysteine-tRNA ligase activity
HZ310_18715	COG1045	serine acetyltransferase
HZ310_18720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HZ310_18725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HZ310_18730	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HZ310_18735	COG4956	integral membrane protein (PIN domain superfamily)
HZ310_18740	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HZ310_18745	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HZ310_18750	COG0542	response to heat
HZ310_18755	COG3869	Catalyzes the specific phosphorylation of arginine residues in
HZ310_18760	COG3880	PFAM UvrB UvrC protein
HZ310_18765	COG4463	regulation of RNA biosynthetic process
HZ310_18850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HZ310_18855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HZ310_18860	COG1396	sequence-specific DNA binding
HZ310_18865	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HZ310_18870	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HZ310_18875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HZ310_18880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HZ310_18885	COG0512	Glutamine amidotransferase of anthranilate synthase
HZ310_18890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HZ310_18895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HZ310_18900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HZ310_18905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HZ310_18910	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HZ310_18915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HZ310_18925	COG0037	tRNA processing
HZ310_18930	COG0515	serine threonine protein kinase
HZ310_18935	COG2304	oxidoreductase activity
HZ310_18940	COG2208	phosphoserine phosphatase activity
HZ310_18955	COG1098	S1 RNA binding domain
HZ310_18960	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HZ310_18975	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HZ310_18980	COG3956	TIGRFAM MazG family protein
HZ310_18985	COG2244	polysaccharide biosynthetic process
HZ310_18990	COG2002	toxin-antitoxin pair type II binding
HZ310_18995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HZ310_19005	COG0193	aminoacyl-tRNA hydrolase activity
HZ310_19010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HZ310_19015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HZ310_19025	COG2088	sporulation resulting in formation of a cellular spore
HZ310_19030	COG0251	oxidation-reduction process
HZ310_19035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HZ310_19040	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HZ310_19050	COG4466	Protein conserved in bacteria
HZ310_19060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HZ310_19065	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HZ310_19070	COG3584	3D domain protein
HZ310_19070	COG3583	domain protein
HZ310_19075	COG0084	hydrolase, TatD family'
HZ310_19080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZ310_19080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HZ310_19085	COG2002	toxin-antitoxin pair type II binding
HZ310_19090	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HZ310_19095	COG2827	Endonuclease containing a URI domain
HZ310_19100	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HZ310_19105	COG4467	Involved in initiation control of chromosome replication
HZ310_19110	COG1774	PSP1 C-terminal conserved region
HZ310_19115	COG0470	DNA polymerase III
HZ310_19120	COG1728	Protein conserved in bacteria
HZ310_19125	COG3870	Protein conserved in bacteria
HZ310_19130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HZ310_19135	COG1982	Orn Lys Arg decarboxylase major
HZ310_19140	COG3853	Toxic anion resistance protein (TelA)
HZ310_19145	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HZ310_19190	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HZ310_19195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HZ310_19200	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HZ310_19210	COG0590	tRNA wobble adenosine to inosine editing
HZ310_19215	COG1335	isochorismatase
HZ310_19220	COG3858	chitin binding
HZ310_19220	COG1388	LysM domain
HZ310_19225	COG1428	Deoxynucleoside kinase
HZ310_19230	COG1428	Deoxynucleoside kinase
HZ310_19240	COG0840	transmembrane signaling receptor activity
HZ310_19245	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HZ310_19250	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HZ310_19255	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HZ310_19260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HZ310_19265	COG1686	Belongs to the peptidase S11 family
HZ310_19270	COG0517	IMP dehydrogenase activity
HZ310_19270	COG0516	GMP reductase activity
HZ310_19305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HZ310_19310	COG0187	DNA topoisomerase II activity
HZ310_19320	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HZ310_19325	COG2501	S4 domain
HZ310_19330	COG0592	DNA-directed DNA polymerase activity
HZ310_19335	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HZ310_19340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HZ310_19345	COG0594	ribonuclease P activity
HZ310_19350	COG0706	membrane insertase activity
HZ310_19355	COG1847	R3H domain protein
HZ310_19360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HZ310_19365	COG0445	tRNA wobble uridine modification
HZ310_19370	COG0357	Ribosomal RNA small subunit methyltransferase G
HZ310_19375	COG1475	DNA binding
HZ310_19385	COG1192	Involved in chromosome partitioning
HZ310_19390	COG1475	DNA binding
HZ310_19400	COG3949	Membrane
HZ310_19415	COG4481	Protein conserved in bacteria
HZ310_19420	COG0012	GTP binding
HZ310_19425	COG0360	Binds together with S18 to 16S ribosomal RNA
HZ310_19430	COG0629	single-stranded DNA binding
HZ310_19435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HZ310_19440	COG0517	IMP dehydrogenase activity
HZ310_19440	COG1125	glycine betaine transport
HZ310_19445	COG1174	glycine betaine transport
HZ310_19450	COG0346	lactoylglutathione lyase activity
HZ310_19455	COG0400	carboxylic ester hydrolase activity
HZ310_19460	COG0655	NAD(P)H dehydrogenase (quinone) activity
HZ310_19465	COG0753	catalase activity
HZ310_19475	COG1595	DNA-templated transcription, initiation
HZ310_19485	COG1227	inorganic diphosphatase activity
HZ310_19490	COG4241	membrane
HZ310_19495	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
HZ310_19500	COG0359	binds to the 23S rRNA
HZ310_19505	COG2807	transmembrane transport
HZ310_19510	COG3093	addiction module antidote protein HigA
HZ310_19515	COG2819	hydrolase of the alpha beta superfamily
HZ310_19520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_19525	COG2207	Transcriptional regulator
HZ310_19525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HZ310_19530	COG3251	PFAM MbtH domain protein
HZ310_19535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HZ310_19540	COG1535	isochorismatase
HZ310_19540	COG3433	isochorismatase activity
HZ310_19545	COG1021	2,3-dihydroxybenzoate-AMP ligase
HZ310_19550	COG1169	isochorismate synthase
HZ310_19555	COG1028	Short-chain dehydrogenase reductase Sdr
HZ310_19560	COG2819	hydrolase of the alpha beta superfamily
HZ310_19575	COG0305	Participates in initiation and elongation during chromosome replication
HZ310_19580	COG0346	lactoylglutathione lyase activity
HZ310_19585	COG2124	cytochrome p450
HZ310_19595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HZ310_19600	COG2311	Membrane
HZ310_19610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HZ310_19635	COG0745	RESPONSE REGULATOR receiver
HZ310_19640	COG5002	protein histidine kinase activity
HZ310_19645	COG4863	YycH protein
HZ310_19650	COG4853	Protein conserved in bacteria
HZ310_19655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HZ310_19660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HZ310_19665	COG0456	acetyltransferase
HZ310_19685	COG4720	Psort location CytoplasmicMembrane, score
HZ310_19695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HZ310_19735	COG0640	Transcriptional regulator
HZ310_19740	COG2814	Major facilitator Superfamily
HZ310_19750	COG2409	Drug exporters of the RND superfamily
HZ310_19760	COG5002	protein histidine kinase activity
HZ310_19760	COG3850	Histidine kinase
HZ310_19775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HZ310_19795	COG0583	DNA-binding transcription factor activity