locus-tag	class	description
DKE43_00005	COG3290	protein histidine kinase activity
DKE43_00010	COG4565	transcriptional regulatory protein
DKE43_00015	COG3181	Tripartite tricarboxylate transporter family receptor
DKE43_00020	COG2851	Citrate transporter
DKE43_00030	COG3479	Phenolic acid decarboxylase
DKE43_00035	COG1695	Transcriptional regulator
DKE43_00040	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DKE43_00045	COG1254	Belongs to the acylphosphatase family
DKE43_00050	COG2258	MOSC domain
DKE43_00060	COG0024	Methionine aminopeptidase
DKE43_00065	COG1263	PTS System
DKE43_00065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_00070	COG3739	integral membrane protein
DKE43_00085	COG1368	sulfuric ester hydrolase activity
DKE43_00095	COG0076	glutamate decarboxylase activity
DKE43_00100	COG0840	transmembrane signaling receptor activity
DKE43_00110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_00110	COG1263	PTS System
DKE43_00115	COG0366	Alpha amylase catalytic
DKE43_00120	COG2188	Transcriptional regulator
DKE43_00130	COG0737	Belongs to the 5'-nucleotidase family
DKE43_00135	COG0693	protein deglycase activity
DKE43_00140	COG4840	Belongs to the UPF0435 family
DKE43_00145	COG1115	amino acid carrier protein
DKE43_00155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DKE43_00160	COG4980	gas vesicle protein
DKE43_00165	COG1295	ribonuclease BN
DKE43_00170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE43_00175	COG0477	Major facilitator Superfamily
DKE43_00185	COG0387	Pfam Sodium calcium exchanger
DKE43_00200	COG4152	abc transporter atp-binding protein
DKE43_00220	COG0217	transcriptional regulatory protein
DKE43_00230	COG0668	transmembrane transport
DKE43_00235	COG0535	radical SAM domain protein
DKE43_00245	COG0726	polysaccharide deacetylase
DKE43_00255	COG0598	Magnesium transport protein CorA
DKE43_00265	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DKE43_00270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKE43_00280	COG0789	Transcriptional regulator
DKE43_00285	COG2814	Major facilitator Superfamily
DKE43_00300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DKE43_00340	COG2076	Multidrug Resistance protein
DKE43_00345	COG2076	Multidrug Resistance protein
DKE43_00350	COG1309	transcriptional regulator
DKE43_00360	COG4637	Psort location Cytoplasmic, score
DKE43_00365	COG2755	lipolytic protein G-D-S-L family
DKE43_00370	COG0492	ferredoxin-NADP+ reductase activity
DKE43_00375	COG1742	UPF0060 membrane protein
DKE43_00390	COG2318	DinB family
DKE43_00400	COG1846	Transcriptional regulator
DKE43_00405	COG0392	lysyltransferase activity
DKE43_00405	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DKE43_00425	COG0778	Nitroreductase
DKE43_00440	COG1090	epimerase
DKE43_00445	COG2137	regulation of response to DNA damage stimulus
DKE43_00470	COG0463	Glycosyl transferase, family 2
DKE43_00475	COG4485	Bacterial membrane protein, YfhO
DKE43_00490	COG2140	Oxalate decarboxylase
DKE43_00500	COG1191	sigma factor activity
DKE43_00510	COG1988	membrane-bound metal-dependent
DKE43_00515	COG1194	a g-specific adenine glycosylase
DKE43_00525	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_00540	COG3557	Belongs to the UPF0374 family
DKE43_00545	COG1132	(ABC) transporter
DKE43_00550	COG0444	Belongs to the ABC transporter superfamily
DKE43_00555	COG4608	Belongs to the ABC transporter superfamily
DKE43_00560	COG0747	negative chemotaxis
DKE43_00575	COG4129	membrane
DKE43_00580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DKE43_00585	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DKE43_00590	COG0735	belongs to the Fur family
DKE43_00730	COG1368	sulfuric ester hydrolase activity
DKE43_00735	COG0681	Belongs to the peptidase S26 family
DKE43_00750	COG1131	(ABC) transporter
DKE43_00780	COG3382	B3 4 domain protein
DKE43_00785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DKE43_00795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DKE43_00805	COG2766	serine protein kinase
DKE43_00810	COG2718	Belongs to the UPF0229 family
DKE43_00815	COG1566	PFAM secretion protein HlyD family protein
DKE43_00820	COG2814	Major facilitator Superfamily
DKE43_00825	COG0655	NAD(P)H dehydrogenase (quinone) activity
DKE43_00835	COG1278	Cold shock
DKE43_00845	COG3706	GGDEF domain
DKE43_00870	COG5577	PFAM Coat F domain
DKE43_00875	COG5002	protein histidine kinase activity
DKE43_00880	COG4085	toxin activity
DKE43_00880	COG0737	Belongs to the 5'-nucleotidase family
DKE43_00880	COG1525	nuclease
DKE43_00885	COG3764	Sortase (surface protein transpeptidase)
DKE43_00890	COG0564	pseudouridine synthase activity
DKE43_00900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DKE43_00905	COG3153	acetyltransferase
DKE43_00905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKE43_00920	COG3835	regulator
DKE43_00925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DKE43_00930	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DKE43_00935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DKE43_00940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DKE43_00945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DKE43_00950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DKE43_00955	COG2203	Gaf domain
DKE43_00955	COG4585	Histidine kinase
DKE43_00960	COG2197	response regulator
DKE43_00985	COG0753	catalase activity
DKE43_00990	COG1959	2 iron, 2 sulfur cluster binding
DKE43_00995	COG1017	nitric oxide dioxygenase activity
DKE43_00995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKE43_01000	COG2719	SpoVR family
DKE43_01005	COG1785	Belongs to the alkaline phosphatase family
DKE43_01010	COG0791	NLP P60 protein
DKE43_01010	COG1388	LysM domain
DKE43_01025	COG1595	DNA-templated transcription, initiation
DKE43_01030	COG0204	Acyl-transferase
DKE43_01035	COG1253	flavin adenine dinucleotide binding
DKE43_01040	COG0789	Transcriptional regulator
DKE43_01045	COG1253	flavin adenine dinucleotide binding
DKE43_01060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DKE43_01065	COG0584	glycerophosphoryl diester phosphodiesterase
DKE43_01075	COG0668	transmembrane transport
DKE43_01080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DKE43_01085	COG0726	polysaccharide deacetylase
DKE43_01095	COG0589	response to stress
DKE43_01100	COG1132	(ABC) transporter
DKE43_01105	COG1132	(ABC) transporter
DKE43_01110	COG0702	epimerase
DKE43_01120	COG3842	ATPase activity
DKE43_01125	COG2508	Transcriptional regulator
DKE43_01135	COG0189	ligase activity
DKE43_01140	COG0189	ligase activity
DKE43_01145	COG4399	Belongs to the UPF0754 family
DKE43_01150	COG3679	Belongs to the UPF0342 family
DKE43_01155	COG0561	phosphatase activity
DKE43_01160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DKE43_01170	COG0475	glutathione-regulated potassium exporter activity
DKE43_01175	COG0490	domain, Protein
DKE43_01185	COG1024	Enoyl-CoA hydratase
DKE43_01195	COG0420	3'-5' exonuclease activity
DKE43_01200	COG4717	serine-type aminopeptidase activity
DKE43_01205	COG3481	metal-dependent phosphohydrolase, HD sub domain
DKE43_01215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKE43_01245	COG1846	Transcriptional regulator
DKE43_01250	COG4980	gas vesicle protein
DKE43_01265	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DKE43_01270	COG0537	adenosine 5'-monophosphoramidase activity
DKE43_01275	COG1131	(ABC) transporter
DKE43_01280	COG4473	ABC transporter
DKE43_01290	COG1473	amidohydrolase
DKE43_01300	COG2329	Antibiotic biosynthesis monooxygenase
DKE43_01305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKE43_01310	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DKE43_01325	COG1309	transcriptional regulator
DKE43_01330	COG1511	domain protein
DKE43_01335	COG1363	Peptidase, m42
DKE43_01340	COG1301	dicarboxylic acid transport
DKE43_01350	COG1234	tRNA 3'-trailer cleavage
DKE43_01355	COG0095	Lipoate-protein ligase
DKE43_01360	COG0318	PFAM AMP-dependent synthetase and ligase
DKE43_01370	COG0501	Belongs to the peptidase M48B family
DKE43_01375	COG1404	Belongs to the peptidase S8 family
DKE43_01380	COG0406	alpha-ribazole phosphatase activity
DKE43_01385	COG0840	transmembrane signaling receptor activity
DKE43_01390	COG0723	plastoquinol--plastocyanin reductase activity
DKE43_01390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKE43_01395	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_01405	COG4903	ComK protein
DKE43_01420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKE43_01425	COG2814	Major facilitator Superfamily
DKE43_01430	COG2732	(Barnase) inhibitor
DKE43_01435	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_01440	COG4605	iron ion homeostasis
DKE43_01445	COG4604	ABC transporter, ATP-binding protein
DKE43_01450	COG4607	ABC-type enterochelin transport system periplasmic component
DKE43_01455	COG1316	TRANSCRIPTIONal
DKE43_01465	COG0398	Pfam SNARE associated Golgi protein
DKE43_01470	COG0681	Belongs to the peptidase S26 family
DKE43_01475	COG3180	Ammonia monooxygenase
DKE43_01490	COG2259	Doxx family
DKE43_01495	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DKE43_01500	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DKE43_01505	COG1074	ATP-dependent DNA helicase activity
DKE43_01510	COG0420	3'-5' exonuclease activity
DKE43_01515	COG0419	ATPase involved in DNA repair
DKE43_01520	COG1403	HNH endonuclease
DKE43_01560	COG5337	Spore coat protein CotH
DKE43_01570	COG0179	Fumarylacetoacetate (FAA) hydrolase
DKE43_01585	COG0367	asparagine synthase
DKE43_01600	COG1562	ergosterol biosynthetic process
DKE43_01605	COG0534	Mate efflux family protein
DKE43_01610	COG2207	Transcriptional regulator
DKE43_01610	COG1917	Cupin 2, conserved barrel domain protein
DKE43_01635	COG0076	glutamate decarboxylase activity
DKE43_01665	COG1410	methionine synthase
DKE43_01665	COG0646	methionine synthase
DKE43_01670	COG0646	methionine synthase
DKE43_01670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DKE43_01675	COG1666	GTP binding
DKE43_01680	COG2996	Protein conserved in bacteria
DKE43_01690	COG0840	transmembrane signaling receptor activity
DKE43_01695	COG1307	EDD domain protein, DegV family
DKE43_01700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKE43_01720	COG0561	phosphatase activity
DKE43_01725	COG1073	alpha beta
DKE43_01730	COG2151	metal-sulfur cluster biosynthetic enzyme
DKE43_01735	COG0277	FAD linked oxidase domain protein
DKE43_01740	COG2271	Major facilitator Superfamily
DKE43_01745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DKE43_01755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DKE43_01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE43_01765	COG0505	Belongs to the CarA family
DKE43_01770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DKE43_01775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DKE43_01785	COG2814	Major facilitator Superfamily
DKE43_01795	COG2267	carboxylic ester hydrolase activity
DKE43_01805	COG1744	ABC transporter substrate-binding protein PnrA-like
DKE43_01820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DKE43_01825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKE43_01830	COG5504	Zn-dependent protease
DKE43_01835	COG0444	Belongs to the ABC transporter superfamily
DKE43_01840	COG4608	Belongs to the ABC transporter superfamily
DKE43_01850	COG0601	transmembrane transport
DKE43_01855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKE43_01865	COG0180	Tryptophanyl-tRNA synthetase
DKE43_01870	COG4166	transmembrane transport
DKE43_01875	COG0601	transmembrane transport
DKE43_01880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKE43_01885	COG0444	Belongs to the ABC transporter superfamily
DKE43_01890	COG4608	Belongs to the ABC transporter superfamily
DKE43_01900	COG0456	acetyltransferase
DKE43_01905	COG1393	Belongs to the ArsC family
DKE43_01910	COG0861	Integral membrane protein TerC family
DKE43_01915	COG4862	establishment of competence for transformation
DKE43_01920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE43_01930	COG1164	Oligoendopeptidase f
DKE43_01940	COG2346	COG2346, Truncated hemoglobins
DKE43_01945	COG0741	lytic transglycosylase activity
DKE43_01950	COG4116	CYTH
DKE43_01960	COG2357	RelA SpoT domain protein
DKE43_01965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKE43_01970	COG0564	pseudouridine synthase activity
DKE43_01975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DKE43_01980	COG0569	domain protein
DKE43_01980	COG0475	glutathione-regulated potassium exporter activity
DKE43_01985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE43_01990	COG0352	thiamine-phosphate diphosphorylase activity
DKE43_02000	COG2104	thiamine diphosphate biosynthetic process
DKE43_02005	COG2022	thiamine diphosphate biosynthetic process
DKE43_02010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DKE43_02015	COG0351	phosphomethylpyrimidine kinase
DKE43_02020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DKE43_02075	COG0210	DNA helicase
DKE43_02085	COG2153	protein acetylation
DKE43_02090	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DKE43_02095	COG2382	esterase
DKE43_02100	COG0626	cystathionine gamma-synthase activity
DKE43_02105	COG0626	cystathionine gamma-synthase activity
DKE43_02115	COG0604	alcohol dehydrogenase
DKE43_02130	COG0825	malonyl-CoA metabolic process
DKE43_02145	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DKE43_02180	COG0457	Tetratricopeptide repeat
DKE43_02200	COG3173	Aminoglycoside phosphotransferase
DKE43_02220	COG0583	DNA-binding transcription factor activity
DKE43_02225	COG2807	transmembrane transport
DKE43_02235	COG0457	Tetratricopeptide repeat
DKE43_02260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKE43_02270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DKE43_02275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DKE43_02295	COG4195	phage-related replication protein
DKE43_02300	COG2856	Zn peptidase
DKE43_02305	COG3409	Peptidoglycan-binding domain 1 protein
DKE43_02305	COG5632	N-Acetylmuramoyl-L-alanine amidase
DKE43_02320	COG0306	phosphate transporter
DKE43_02325	COG1392	Phosphate transport regulator
DKE43_02335	COG0405	Gamma-glutamyltransferase
DKE43_02345	COG3775	system Galactitol-specific IIC component
DKE43_02365	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE43_02370	COG0022	dehydrogenase e1 component
DKE43_02370	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE43_02375	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE43_02380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE43_02385	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_02390	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_02395	COG2390	Transcriptional regulator
DKE43_02405	COG0531	amino acid
DKE43_02410	COG0346	lactoylglutathione lyase activity
DKE43_02415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKE43_02420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DKE43_02425	COG2362	D-Aminopeptidase
DKE43_02430	COG0601	transmembrane transport
DKE43_02435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKE43_02440	COG0444	Belongs to the ABC transporter superfamily
DKE43_02445	COG4166	transmembrane transport
DKE43_02450	COG1619	proteins homologs of microcin C7 resistance protein MccF
DKE43_02455	COG4948	Mandelate Racemase Muconate Lactonizing
DKE43_02460	COG0791	NLP P60 protein
DKE43_02465	COG4608	Belongs to the ABC transporter superfamily
DKE43_02470	COG1834	amidinotransferase
DKE43_02475	COG1607	acyl-coa hydrolase
DKE43_02480	COG1695	Transcriptional regulator
DKE43_02495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE43_02505	COG2076	Multidrug Resistance protein
DKE43_02510	COG2076	Multidrug Resistance protein
DKE43_02520	COG0788	formyltetrahydrofolate deformylase activity
DKE43_02525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DKE43_02530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DKE43_02535	COG0457	Tetratricopeptide repeat
DKE43_02545	COG1764	response to oxidative stress
DKE43_02550	COG1846	Transcriptional regulator
DKE43_02555	COG1764	response to oxidative stress
DKE43_02560	COG0590	tRNA wobble adenosine to inosine editing
DKE43_02565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DKE43_02570	COG1404	Belongs to the peptidase S8 family
DKE43_02575	COG0745	RESPONSE REGULATOR receiver
DKE43_02580	COG5002	protein histidine kinase activity
DKE43_02580	COG3850	Histidine kinase
DKE43_02585	COG3212	peptidase
DKE43_02590	COG3212	peptidase
DKE43_02600	COG2239	Acts as a magnesium transporter
DKE43_02615	COG0583	DNA-binding transcription factor activity
DKE43_02625	COG0789	Transcriptional regulator
DKE43_02640	COG1846	Transcriptional regulator
DKE43_02650	COG3300	MHYT domain
DKE43_02650	COG5001	Diguanylate cyclase
DKE43_02655	COG0586	Pfam SNARE associated Golgi protein
DKE43_02660	COG0861	Integral membrane protein TerC family
DKE43_02665	COG1191	sigma factor activity
DKE43_02685	COG0501	Belongs to the peptidase M48B family
DKE43_02690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DKE43_02695	COG2323	membrane
DKE43_02705	COG3594	Acyltransferase
DKE43_02710	COG5002	protein histidine kinase activity
DKE43_02715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKE43_02720	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DKE43_02725	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DKE43_02730	COG0436	Aminotransferase
DKE43_02735	COG1850	ribulose-bisphosphate carboxylase activity
DKE43_02740	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
DKE43_02745	COG0235	Class ii aldolase
DKE43_02750	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
DKE43_02760	COG3852	Histidine kinase
DKE43_02765	COG1846	Transcriptional regulator
DKE43_02770	COG1360	Flagellar Motor Protein
DKE43_02775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DKE43_02780	COG0542	response to heat
DKE43_02785	COG3949	Membrane
DKE43_02790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DKE43_02795	COG0720	synthase
DKE43_02800	COG0602	queuosine metabolic process
DKE43_02805	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DKE43_02815	COG4873	Protein conserved in bacteria
DKE43_02825	COG3773	Cell wall hydrolase
DKE43_02830	COG2244	polysaccharide biosynthetic process
DKE43_02835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_02840	COG2217	Heavy metal translocating P-type atpase
DKE43_02845	COG0006	proline dipeptidase activity
DKE43_02850	COG1609	Transcriptional regulator
DKE43_02855	COG3711	transcriptional antiterminator
DKE43_02860	COG2190	(PTS) system
DKE43_02860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_02860	COG1263	PTS System
DKE43_02865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_02870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DKE43_02880	COG1533	DNA photolyase activity
DKE43_02885	COG0840	transmembrane signaling receptor activity
DKE43_02895	COG2084	Dehydrogenase
DKE43_02900	COG2340	Cysteine-rich secretory protein family
DKE43_02905	COG0768	penicillin binding
DKE43_02910	COG4191	Histidine kinase
DKE43_02915	COG0436	Aminotransferase
DKE43_02920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DKE43_02925	COG1714	RDD family
DKE43_02935	COG0835	chemotaxis
DKE43_02935	COG0784	Response regulator, receiver
DKE43_02955	COG2814	Major facilitator Superfamily
DKE43_02960	COG1376	ErfK ybiS ycfS ynhG family protein
DKE43_02965	COG1408	metallophosphoesterase
DKE43_02970	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_02975	COG2200	EAL domain
DKE43_02980	COG3546	catalase activity
DKE43_02985	COG4703	Protein of unknown function (DUF1797)
DKE43_02990	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DKE43_03000	COG0517	IMP dehydrogenase activity
DKE43_03005	COG0583	DNA-binding transcription factor activity
DKE43_03015	COG0716	FMN binding
DKE43_03025	COG0716	FMN binding
DKE43_03030	COG2171	N-acyltransferase activity
DKE43_03035	COG1473	amidohydrolase
DKE43_03045	COG0668	transmembrane transport
DKE43_03050	COG0450	alkyl hydroperoxide reductase
DKE43_03055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_03070	COG0746	molybdenum cofactor guanylyltransferase activity
DKE43_03075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DKE43_03080	COG0303	'Molybdopterin
DKE43_03085	COG1763	Mo-molybdopterin cofactor biosynthetic process
DKE43_03090	COG0314	molybdopterin synthase activity
DKE43_03095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DKE43_03110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKE43_03115	COG1136	(ABC) transporter
DKE43_03120	COG0577	efflux transmembrane transporter activity
DKE43_03125	COG1349	DNA-binding transcription factor activity
DKE43_03130	COG1105	Belongs to the carbohydrate kinase PfkB family
DKE43_03135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_03135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_03135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_03140	COG0681	Belongs to the peptidase S26 family
DKE43_03150	COG0488	(ABC) transporter
DKE43_03155	COG2309	aminopeptidase activity
DKE43_03160	COG1077	Cell shape determining protein MreB Mrl
DKE43_03165	COG2002	toxin-antitoxin pair type II binding
DKE43_03170	COG3852	Histidine kinase
DKE43_03175	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
DKE43_03175	COG2105	PFAM AIG2 family protein
DKE43_03180	COG0569	domain protein
DKE43_03185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DKE43_03190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DKE43_03200	COG0561	phosphatase activity
DKE43_03205	COG0242	peptide deformylase activity
DKE43_03220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE43_03225	COG0022	dehydrogenase e1 component
DKE43_03230	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE43_03235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE43_03240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_03255	COG1982	Orn Lys Arg decarboxylase major
DKE43_03260	COG4476	Belongs to the UPF0223 family
DKE43_03265	COG4493	Belongs to the UPF0637 family
DKE43_03275	COG0483	inositol monophosphate 1-phosphatase activity
DKE43_03290	COG1595	DNA-templated transcription, initiation
DKE43_03320	COG4896	Protein conserved in bacteria
DKE43_03330	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DKE43_03335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DKE43_03340	COG2066	Belongs to the glutaminase family
DKE43_03345	COG4838	Belongs to the UPF0358 family
DKE43_03350	COG0772	Belongs to the SEDS family
DKE43_03355	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DKE43_03365	COG1612	heme a metabolic process
DKE43_03370	COG0109	protoheme IX farnesyltransferase activity
DKE43_03375	COG2010	Cytochrome c
DKE43_03375	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DKE43_03380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DKE43_03385	COG1845	cytochrome c oxidase, subunit III
DKE43_03390	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DKE43_03395	COG3336	cytochrome c oxidase
DKE43_03410	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DKE43_03415	COG2340	Cysteine-rich secretory protein family
DKE43_03435	COG3679	Belongs to the UPF0342 family
DKE43_03440	COG4471	UPF0298 protein
DKE43_03445	COG0742	ribosomal rna small subunit methyltransferase
DKE43_03450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DKE43_03455	COG3314	Sporulation integral membrane protein YlbJ
DKE43_03460	COG1752	Esterase of the alpha-beta hydrolase superfamily
DKE43_03465	COG3480	Lon protease (S16) C-terminal proteolytic domain
DKE43_03475	COG1399	metal-binding, possibly nucleic acid-binding protein
DKE43_03480	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DKE43_03490	COG0454	-acetyltransferase
DKE43_03495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DKE43_03500	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
DKE43_03505	COG2001	Belongs to the MraZ family
DKE43_03510	COG0275	rRNA processing
DKE43_03515	COG4839	cell division protein FtsL
DKE43_03530	COG0768	penicillin binding
DKE43_03535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DKE43_03540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKE43_03545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DKE43_03550	COG0772	Belongs to the SEDS family
DKE43_03555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DKE43_03560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DKE43_03565	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DKE43_03570	COG3879	Bacterial protein of unknown function (DUF881)
DKE43_03575	COG3879	Bacterial protein of unknown function (DUF881)
DKE43_03580	COG3856	small basic protein
DKE43_03585	COG0849	cell division
DKE43_03590	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DKE43_03595	COG1404	Belongs to the peptidase S8 family
DKE43_03595	COG4412	M6 family metalloprotease domain protein
DKE43_03605	COG1191	sigma factor activity
DKE43_03610	COG1191	sigma factor activity
DKE43_03615	COG2390	Transcriptional regulator
DKE43_03630	COG3730	PTS system glucitol sorbitol-specific
DKE43_03635	COG3732	PTS system glucitol sorbitol-specific
DKE43_03645	COG1119	ATPase activity
DKE43_03650	COG1873	PFAM PRC-barrel domain
DKE43_03660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DKE43_03665	COG1799	cell septum assembly
DKE43_03670	COG0762	integral membrane protein
DKE43_03675	COG2302	S4 RNA-binding domain
DKE43_03680	COG3599	regulation of cell shape
DKE43_03685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DKE43_03690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKE43_03695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DKE43_03700	COG0564	pseudouridine synthase activity
DKE43_03705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DKE43_03710	COG2233	PERMEase
DKE43_03715	COG0540	Belongs to the ATCase OTCase family
DKE43_03720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DKE43_03725	COG0505	Belongs to the CarA family
DKE43_03730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DKE43_03735	COG0543	2 iron, 2 sulfur cluster binding
DKE43_03740	COG0167	dihydroorotate dehydrogenase activity
DKE43_03745	COG0284	orotidine-5'-phosphate decarboxylase activity
DKE43_03750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DKE43_03760	COG0175	sulfate reduction
DKE43_03765	COG0306	phosphate transporter
DKE43_03770	COG2046	Belongs to the sulfate adenylyltransferase family
DKE43_03775	COG0529	Catalyzes the synthesis of activated sulfate
DKE43_03780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DKE43_03785	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
DKE43_03790	COG1648	precorrin-2 dehydrogenase activity
DKE43_03800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DKE43_03805	COG1561	YicC-like family, N-terminal region
DKE43_03810	COG2052	Domain of unknown function (DUF370)
DKE43_03815	COG0194	GDP metabolic process
DKE43_03820	COG1758	RNA polymerase activity
DKE43_03825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DKE43_03830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DKE43_03835	COG0242	peptide deformylase activity
DKE43_03840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DKE43_03845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DKE43_03845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKE43_03850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DKE43_03855	COG0631	protein serine/threonine phosphatase activity
DKE43_03860	COG2815	serine threonine protein kinase
DKE43_03860	COG0515	serine threonine protein kinase
DKE43_03865	COG1162	GTPase activity
DKE43_03870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKE43_03875	COG1564	THIamine pyrophosphokinase
DKE43_03885	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DKE43_03890	COG1302	Protein conserved in bacteria
DKE43_03895	COG1461	Dihydroxyacetone kinase
DKE43_03900	COG1760	l-serine dehydratase
DKE43_03905	COG1760	l-serine dehydratase
DKE43_03910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DKE43_03915	COG1349	DNA-binding transcription factor activity
DKE43_03920	COG0416	fatty acid biosynthetic process
DKE43_03925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DKE43_03930	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_03935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKE43_03945	COG1196	nuclear chromosome segregation
DKE43_03950	COG0552	protein localization to endoplasmic reticulum
DKE43_03955	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DKE43_03960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DKE43_03965	COG0228	four-way junction DNA binding
DKE43_03970	COG1837	Belongs to the UPF0109 family
DKE43_03980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKE43_03985	COG0336	Belongs to the RNA methyltransferase TrmD family
DKE43_03990	COG0335	large ribosomal subunit rRNA binding
DKE43_03995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DKE43_04000	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKE43_04010	COG2257	FlhB HrpN YscU SpaS Family
DKE43_04015	COG0045	succinate-CoA ligase (ADP-forming) activity
DKE43_04020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DKE43_04025	COG0758	DNA mediated transformation
DKE43_04030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DKE43_04035	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DKE43_04040	COG4974	Belongs to the 'phage' integrase family
DKE43_04045	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DKE43_04050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DKE43_04055	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DKE43_04060	COG1815	bacterial-type flagellum-dependent cell motility
DKE43_04065	COG1558	bacterial-type flagellum-dependent cell motility
DKE43_04070	COG1677	Flagellar hook-basal body complex protein FliE
DKE43_04075	COG1766	The M ring may be actively involved in energy transduction
DKE43_04080	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DKE43_04085	COG1317	bacterial-type flagellum organization
DKE43_04090	COG1157	protein secretion by the type III secretion system
DKE43_04095	COG2882	bacterial-type flagellum organization
DKE43_04100	COG3334	PFAM MgtE intracellular
DKE43_04105	COG3144	bacterial-type flagellum assembly
DKE43_04110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DKE43_04115	COG4786	Flagellar basal body rod
DKE43_04120	COG1582	Flagellar protein (FlbD)
DKE43_04125	COG1580	Controls the rotational direction of flagella during chemotaxis
DKE43_04130	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DKE43_04135	COG1776	CheC inhibitor of MCP methylation
DKE43_04135	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DKE43_04140	COG2201	protein-glutamate methylesterase activity
DKE43_04145	COG3190	flagellar
DKE43_04150	COG1338	Plays a role in the flagellum-specific transport system
DKE43_04155	COG1987	bacterial-type flagellum assembly
DKE43_04160	COG1684	flagellar biosynthetic protein fliR
DKE43_04165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DKE43_04170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DKE43_04175	COG1419	protein localization to endoplasmic reticulum
DKE43_04180	COG0455	bacterial-type flagellum organization
DKE43_04185	COG2201	protein-glutamate methylesterase activity
DKE43_04190	COG2198	Histidine kinase
DKE43_04190	COG0643	Histidine kinase
DKE43_04195	COG0835	chemotaxis
DKE43_04200	COG1776	CheC inhibitor of MCP methylation
DKE43_04210	COG1191	sigma factor activity
DKE43_04220	COG0052	Belongs to the universal ribosomal protein uS2 family
DKE43_04225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DKE43_04230	COG0528	UMP kinase activity
DKE43_04235	COG0233	cytoplasmic translational termination
DKE43_04240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DKE43_04245	COG4589	Belongs to the CDS family
DKE43_04250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DKE43_04255	COG0750	zinc metalloprotease
DKE43_04260	COG0442	prolyl-tRNA aminoacylation
DKE43_04265	COG2176	DNA-directed DNA polymerase activity
DKE43_04290	COG0779	Required for maturation of 30S ribosomal subunits
DKE43_04295	COG0195	Participates in both transcription termination and antitermination
DKE43_04300	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DKE43_04305	COG1358	cellular component organization or biogenesis
DKE43_04310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DKE43_04315	COG1550	Protein conserved in bacteria
DKE43_04320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKE43_04325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DKE43_04330	COG0196	riboflavin kinase activity
DKE43_04335	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DKE43_04340	COG1185	polyribonucleotide nucleotidyltransferase activity
DKE43_04345	COG0726	polysaccharide deacetylase
DKE43_04350	COG0612	Peptidase, M16
DKE43_04360	COG1873	PFAM PRC-barrel domain
DKE43_04365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKE43_04370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DKE43_04375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DKE43_04380	COG0527	aspartate kinase activity
DKE43_04390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DKE43_04395	COG0740	serine-type endopeptidase activity
DKE43_04405	COG1674	ftsk spoiiie
DKE43_04405	COG4980	gas vesicle protein
DKE43_04410	COG2188	Transcriptional regulator
DKE43_04415	COG2814	Major facilitator Superfamily
DKE43_04420	COG2409	Drug exporters of the RND superfamily
DKE43_04420	COG1033	growth of symbiont in host cell
DKE43_04425	COG0612	Peptidase, M16
DKE43_04430	COG0612	Peptidase, M16
DKE43_04440	COG2409	Drug exporters of the RND superfamily
DKE43_04440	COG1033	growth of symbiont in host cell
DKE43_04445	COG0300	oxidoreductase activity
DKE43_04460	COG1426	Protein conserved in bacteria
DKE43_04465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKE43_04470	COG1546	Belongs to the CinA family
DKE43_04470	COG1058	Belongs to the CinA family
DKE43_04475	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DKE43_04480	COG1418	mRNA catabolic process
DKE43_04485	COG1692	metallophosphoesterase
DKE43_04490	COG2359	stage V sporulation protein S
DKE43_04495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKE43_04500	COG1063	alcohol dehydrogenase
DKE43_04505	COG0156	8-amino-7-oxononanoate synthase activity
DKE43_04515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKE43_04520	COG4550	Control of competence regulator ComK, YlbF/YmcA
DKE43_04530	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DKE43_04535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DKE43_04560	COG1329	Transcriptional regulator
DKE43_04565	COG4195	phage-related replication protein
DKE43_04570	COG0457	Tetratricopeptide repeat
DKE43_04575	COG1404	Belongs to the peptidase S8 family
DKE43_04580	COG4195	phage-related replication protein
DKE43_04585	COG1764	response to oxidative stress
DKE43_04590	COG2076	Multidrug Resistance protein
DKE43_04615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DKE43_04620	COG1923	regulation of RNA biosynthetic process
DKE43_04635	COG1780	Probably involved in ribonucleotide reductase function
DKE43_04640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKE43_04645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKE43_04650	COG4112	unkown
DKE43_04660	COG0464	growth
DKE43_04665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DKE43_04670	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DKE43_04675	COG0789	Transcriptional regulator
DKE43_04680	COG0174	glutamine synthetase
DKE43_04690	COG0457	Tetratricopeptide repeat
DKE43_04695	COG5444	nuclease activity
DKE43_04720	COG5646	InterPro IPR014922
DKE43_04735	COG0457	Tetratricopeptide repeat
DKE43_04745	COG3619	membrane
DKE43_04750	COG1793	dna ligase
DKE43_04750	COG3285	dna ligase
DKE43_04755	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
DKE43_04760	COG4876	unkown
DKE43_04770	COG1959	2 iron, 2 sulfur cluster binding
DKE43_04775	COG0702	epimerase
DKE43_04780	COG0247	lactate metabolic process
DKE43_04785	COG1139	Iron-sulfur cluster binding protein
DKE43_04790	COG1556	Lactate utilization protein
DKE43_04815	COG1309	transcriptional regulator
DKE43_04820	COG2124	cytochrome p450
DKE43_04820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DKE43_04830	COG3591	Belongs to the peptidase S1B family
DKE43_04835	COG3209	COG3209 Rhs family protein
DKE43_04840	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_04855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKE43_04860	COG1388	LysM domain
DKE43_04865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DKE43_04870	COG4224	UPF0291 protein
DKE43_04875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DKE43_04885	COG3763	UPF0154 protein
DKE43_04895	COG0785	Cytochrome C biogenesis protein
DKE43_04900	COG4846	Membrane protein involved in cytochrome C biogenesis
DKE43_04910	COG0071	Belongs to the small heat shock protein (HSP20) family
DKE43_04925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DKE43_04930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_04950	COG0824	Thioesterase
DKE43_04960	COG4841	protein insertion into membrane
DKE43_04965	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DKE43_04970	COG1832	CoA-binding protein
DKE43_04980	COG0187	DNA topoisomerase II activity
DKE43_04985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DKE43_04995	COG0738	Major facilitator superfamily
DKE43_05000	COG0473	3-isopropylmalate dehydrogenase activity
DKE43_05010	COG0583	DNA-binding transcription factor activity
DKE43_05035	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DKE43_05040	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DKE43_05045	COG0640	Transcriptional regulator
DKE43_05050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE43_05055	COG0251	oxidation-reduction process
DKE43_05085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DKE43_05105	COG0657	acetylesterase activity
DKE43_05120	COG2205	protein histidine kinase activity
DKE43_05125	COG0745	RESPONSE REGULATOR receiver
DKE43_05135	COG3507	Belongs to the glycosyl hydrolase 43 family
DKE43_05140	COG1012	belongs to the aldehyde dehydrogenase family
DKE43_05145	COG1486	melibiose metabolic process
DKE43_05170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKE43_05185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_05200	COG1846	Transcriptional regulator
DKE43_05205	COG2814	Major facilitator Superfamily
DKE43_05215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_05215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_05215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_05220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_05220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_05220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_05225	COG1105	Belongs to the carbohydrate kinase PfkB family
DKE43_05235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE43_05265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DKE43_05270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKE43_05275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKE43_05280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DKE43_05285	COG1024	Enoyl-CoA hydratase
DKE43_05290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKE43_05295	COG0511	ligase activity, forming carbon-carbon bonds
DKE43_05300	COG0439	Biotin carboxylase
DKE43_05305	COG0318	PFAM AMP-dependent synthetase and ligase
DKE43_05310	COG1960	acyl-CoA dehydrogenase activity
DKE43_05315	COG1649	PFAM Uncharacterised BCR, COG1649
DKE43_05325	COG1349	DNA-binding transcription factor activity
DKE43_05340	COG0277	FAD linked oxidase domain protein
DKE43_05345	COG0247	lactate metabolic process
DKE43_05370	COG0166	Belongs to the GPI family
DKE43_05380	COG0586	Pfam SNARE associated Golgi protein
DKE43_05385	COG1587	Uroporphyrinogen-III synthase
DKE43_05395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE43_05415	COG1846	Transcriptional regulator
DKE43_05425	COG2085	NADP oxidoreductase coenzyme F420-dependent
DKE43_05445	COG0534	Mate efflux family protein
DKE43_05450	COG2027	D-alanyl-D-alanine carboxypeptidase
DKE43_05455	COG4677	pectinesterase activity
DKE43_05460	COG2323	membrane
DKE43_05465	COG2146	nitrite reductase [NAD(P)H] activity
DKE43_05470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKE43_05475	COG0243	molybdopterin cofactor binding
DKE43_05480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKE43_05485	COG2223	nitrite transmembrane transporter activity
DKE43_05490	COG0493	'glutamate synthase
DKE43_05495	COG0070	glutamate synthase
DKE43_05495	COG0069	glutamate synthase activity
DKE43_05495	COG0067	glutamate synthase
DKE43_05500	COG0583	DNA-binding transcription factor activity
DKE43_05520	COG0454	-acetyltransferase
DKE43_05525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DKE43_05530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DKE43_05545	COG0243	molybdopterin cofactor binding
DKE43_05555	COG1070	Carbohydrate kinase
DKE43_05560	COG2115	Belongs to the xylose isomerase family
DKE43_05565	COG1940	carbohydrate kinase activity
DKE43_05575	COG2211	Major facilitator Superfamily
DKE43_05580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE43_05585	COG1994	Peptidase M50
DKE43_05605	COG1309	transcriptional regulator
DKE43_05610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE43_05615	COG3708	Transcriptional regulator
DKE43_05620	COG2378	regulation of single-species biofilm formation
DKE43_05630	COG0640	Transcriptional regulator
DKE43_05635	COG0531	amino acid
DKE43_05640	COG0741	lytic transglycosylase activity
DKE43_05645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DKE43_05650	COG2079	MmgE PrpD family protein
DKE43_05655	COG0372	Belongs to the citrate synthase family
DKE43_05660	COG2322	membrane
DKE43_05670	COG1388	LysM domain
DKE43_05670	COG3584	3D domain protein
DKE43_05675	COG0514	ATP-dependent DNA helicase (RecQ)
DKE43_05685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKE43_05710	COG1012	belongs to the aldehyde dehydrogenase family
DKE43_05715	COG1657	PFAM Prenyltransferase squalene oxidase
DKE43_05720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DKE43_05725	COG0385	Bile acid
DKE43_05730	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE43_05735	COG0567	Dehydrogenase, E1 component
DKE43_05740	COG4548	von Willebrand factor, type A
DKE43_05745	COG0714	Associated with various cellular activities
DKE43_05750	COG2032	superoxide dismutase activity
DKE43_05755	COG1388	LysM domain
DKE43_05755	COG0791	NLP P60 protein
DKE43_05760	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DKE43_05765	COG0534	Mate efflux family protein
DKE43_05770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DKE43_05775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DKE43_05785	COG2962	Rard protein
DKE43_05800	COG1733	regulation of RNA biosynthetic process
DKE43_05805	COG0778	Nitroreductase
DKE43_05815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE43_05820	COG0793	Belongs to the peptidase S41A family
DKE43_05820	COG3409	Peptidoglycan-binding domain 1 protein
DKE43_05825	COG2226	methyltransferase
DKE43_05835	COG1876	peptidase activity
DKE43_05840	COG0813	purine-nucleoside phosphorylase activity
DKE43_05850	COG0671	phosphoesterase, PA-phosphatase related
DKE43_05865	COG4479	Belongs to the UPF0346 family
DKE43_05875	COG1509	lysine 2,3-aminomutase activity
DKE43_05880	COG3829	transcription factor binding
DKE43_05885	COG0463	Glycosyl transferase, family 2
DKE43_05900	COG4641	Protein conserved in bacteria
DKE43_05910	COG1086	Polysaccharide biosynthesis protein
DKE43_05915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKE43_05920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKE43_05925	COG1846	Transcriptional regulator
DKE43_05945	COG4698	Protein conserved in bacteria
DKE43_05950	COG2755	lipolytic protein G-D-S-L family
DKE43_05955	COG1999	signal sequence binding
DKE43_05970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKE43_05975	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DKE43_05980	COG1272	protein, Hemolysin III
DKE43_05985	COG0204	Acyl-transferase
DKE43_05990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DKE43_05995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DKE43_06000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DKE43_06010	COG2136	Putative SAM-dependent methyltransferase
DKE43_06010	COG2521	methyltransferase
DKE43_06020	COG0129	dihydroxy-acid dehydratase activity
DKE43_06025	COG1413	lyase activity
DKE43_06030	COG1418	mRNA catabolic process
DKE43_06035	COG0386	Belongs to the glutathione peroxidase family
DKE43_06040	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DKE43_06045	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DKE43_06050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DKE43_06060	COG1278	Cold shock
DKE43_06075	COG0328	RNA-DNA hybrid ribonuclease activity
DKE43_06080	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DKE43_06085	COG0328	RNA-DNA hybrid ribonuclease activity
DKE43_06095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKE43_06105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DKE43_06115	COG1755	Isoprenylcysteine carboxyl methyltransferase
DKE43_06120	COG3424	synthase
DKE43_06130	COG2233	PERMEase
DKE43_06135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DKE43_06140	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DKE43_06145	COG1199	ATP-dependent helicase activity
DKE43_06155	COG0116	Belongs to the methyltransferase superfamily
DKE43_06165	COG3599	regulation of cell shape
DKE43_06180	COG3359	exonuclease
DKE43_06185	COG1111	helicase
DKE43_06185	COG1205	dead DEAH box helicase
DKE43_06190	COG1902	pentaerythritol trinitrate reductase activity
DKE43_06195	COG2190	(PTS) system
DKE43_06200	COG0071	Belongs to the small heat shock protein (HSP20) family
DKE43_06230	COG3331	DNA recombination
DKE43_06235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKE43_06235	COG4499	WXG100 protein secretion system (Wss), protein YukC
DKE43_06245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKE43_06250	COG3935	DnaD domain protein
DKE43_06255	COG0017	Asparaginyl-tRNA synthetase
DKE43_06260	COG5353	protein conserved in bacteria
DKE43_06270	COG1199	ATP-dependent helicase activity
DKE43_06270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DKE43_06275	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DKE43_06280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DKE43_06285	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DKE43_06295	COG0617	tRNA 3'-terminal CCA addition
DKE43_06300	COG0438	transferase activity, transferring glycosyl groups
DKE43_06305	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DKE43_06310	COG1803	Methylglyoxal synthase
DKE43_06315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DKE43_06320	COG1694	Mazg nucleotide pyrophosphohydrolase
DKE43_06325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKE43_06335	COG4347	Protein of unknown function (DUF1405)
DKE43_06340	COG2010	Cytochrome c
DKE43_06340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DKE43_06345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DKE43_06350	COG0723	plastoquinol--plastocyanin reductase activity
DKE43_06360	COG5582	Belongs to the UPF0302 family
DKE43_06365	COG0457	Tetratricopeptide repeat
DKE43_06370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DKE43_06375	COG0287	Prephenate dehydrogenase
DKE43_06380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DKE43_06385	COG0159	tryptophan synthase activity
DKE43_06390	COG0133	tryptophan synthase activity
DKE43_06395	COG0135	phosphoribosylanthranilate isomerase activity
DKE43_06400	COG0134	indole-3-glycerol-phosphate synthase activity
DKE43_06405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DKE43_06415	COG4401	Chorismate mutase type I
DKE43_06420	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DKE43_06425	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DKE43_06430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DKE43_06435	COG0105	UTP biosynthetic process
DKE43_06440	COG0142	geranyltranstransferase activity
DKE43_06445	COG2226	methyltransferase
DKE43_06450	COG0142	geranyltranstransferase activity
DKE43_06460	COG0302	gtp cyclohydrolase
DKE43_06465	COG0776	regulation of translation
DKE43_06475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DKE43_06490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DKE43_06495	COG1160	GTP binding
DKE43_06520	COG1304	FMN binding
DKE43_06525	COG0539	negative regulation of cytoplasmic translation
DKE43_06530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DKE43_06540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DKE43_06545	COG2959	enzyme of heme biosynthesis
DKE43_06550	COG3409	Peptidoglycan-binding domain 1 protein
DKE43_06550	COG3773	Cell wall hydrolase
DKE43_06555	COG2339	peptidase activity
DKE43_06560	COG0492	ferredoxin-NADP+ reductase activity
DKE43_06565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DKE43_06570	COG4862	establishment of competence for transformation
DKE43_06575	COG1408	metallophosphoesterase
DKE43_06585	COG1388	LysM domain
DKE43_06590	COG1266	CAAX protease self-immunity
DKE43_06595	COG0514	ATP-dependent DNA helicase (RecQ)
DKE43_06600	COG4955	Helix-turn-helix domain
DKE43_06605	COG1141	Ferredoxin
DKE43_06610	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DKE43_06615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DKE43_06620	COG3409	Peptidoglycan-binding domain 1 protein
DKE43_06620	COG5632	N-Acetylmuramoyl-L-alanine amidase
DKE43_06630	COG1595	DNA-templated transcription, initiation
DKE43_06635	COG5002	protein histidine kinase activity
DKE43_06640	COG0745	RESPONSE REGULATOR receiver
DKE43_06645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DKE43_06650	COG1333	cytochrome c biogenesis protein
DKE43_06655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_06660	COG1187	pseudouridine synthase activity
DKE43_06665	COG0700	Nucleoside recognition
DKE43_06670	COG2715	membrane protein required for spore maturation
DKE43_06675	COG1686	Belongs to the peptidase S11 family
DKE43_06685	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKE43_06690	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DKE43_06700	COG1547	Domain of unknown function (DUF309)
DKE43_06705	COG0456	acetyltransferase
DKE43_06710	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DKE43_06715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKE43_06715	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKE43_06720	COG0307	riboflavin synthase, alpha
DKE43_06745	COG2814	Major facilitator Superfamily
DKE43_06750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DKE43_06755	COG4086	secreted protein
DKE43_06760	COG0019	diaminopimelate decarboxylase activity
DKE43_06765	COG0697	spore germination
DKE43_06780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DKE43_06800	COG1191	sigma factor activity
DKE43_06805	COG2172	sigma factor antagonist activity
DKE43_06815	COG1686	Belongs to the peptidase S11 family
DKE43_06820	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DKE43_06825	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DKE43_06830	COG4974	Belongs to the 'phage' integrase family
DKE43_06840	COG0735	belongs to the Fur family
DKE43_06845	COG1300	Membrane
DKE43_06850	COG1404	Belongs to the peptidase S8 family
DKE43_06860	COG2153	protein acetylation
DKE43_06865	COG1379	DNA repair
DKE43_06870	COG0494	nUDIX hydrolase
DKE43_06875	COG0667	Aldo Keto reductase
DKE43_06890	COG1073	alpha beta
DKE43_06895	COG0457	Tetratricopeptide repeat
DKE43_06905	COG4918	Iron-sulphur cluster biosynthesis
DKE43_06910	COG4305	rare lipoprotein A
DKE43_06915	COG0456	acetyltransferase
DKE43_06915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DKE43_06920	COG0456	acetyltransferase
DKE43_06930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKE43_06940	COG2211	Major facilitator Superfamily
DKE43_06945	COG1072	(Pantothenic acid kinase))
DKE43_06950	COG0446	pyridine nucleotide-disulphide oxidoreductase
DKE43_06955	COG0300	oxidoreductase activity
DKE43_06960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE43_06965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DKE43_06975	COG4187	Peptidase family M20/M25/M40
DKE43_06980	COG1902	pentaerythritol trinitrate reductase activity
DKE43_06985	COG0596	Alpha beta hydrolase
DKE43_06990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKE43_06995	COG1234	tRNA 3'-trailer cleavage
DKE43_07000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DKE43_07005	COG2188	Transcriptional regulator
DKE43_07010	COG2723	6-phospho-beta-galactosidase activity
DKE43_07015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKE43_07020	COG1447	Phosphotransferase system cellobiose-specific component IIA
DKE43_07025	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKE43_07030	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_07035	COG4975	Glucose uptake
DKE43_07040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DKE43_07045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKE43_07055	COG0706	membrane insertase activity
DKE43_07065	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKE43_07070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DKE43_07075	COG0346	lactoylglutathione lyase activity
DKE43_07080	COG1376	ErfK ybiS ycfS ynhG family protein
DKE43_07085	COG4129	membrane
DKE43_07090	COG1126	abc transporter atp-binding protein
DKE43_07095	COG0765	amino acid transport
DKE43_07100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_07110	COG1597	lipid kinase activity
DKE43_07120	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE43_07125	COG0022	dehydrogenase e1 component
DKE43_07130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE43_07135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE43_07140	COG3426	butyrate kinase activity
DKE43_07145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DKE43_07150	COG0280	phosphate acetyltransferase
DKE43_07155	COG3829	transcription factor binding
DKE43_07155	COG3290	protein histidine kinase activity
DKE43_07165	COG0584	glycerophosphoryl diester phosphodiesterase
DKE43_07170	COG0457	Tetratricopeptide repeat
DKE43_07180	COG0745	RESPONSE REGULATOR receiver
DKE43_07185	COG0750	zinc metalloprotease
DKE43_07190	COG0497	DNA recombination
DKE43_07195	COG1438	arginine binding
DKE43_07200	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DKE43_07205	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DKE43_07210	COG0142	geranyltranstransferase activity
DKE43_07215	COG1722	exodeoxyribonuclease VII activity
DKE43_07220	COG1570	exodeoxyribonuclease VII activity
DKE43_07225	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DKE43_07230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKE43_07235	COG1302	Protein conserved in bacteria
DKE43_07240	COG0439	Biotin carboxylase
DKE43_07245	COG0511	ligase activity, forming carbon-carbon bonds
DKE43_07285	COG3854	ATPases associated with a variety of cellular activities
DKE43_07300	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKE43_07305	COG0006	proline dipeptidase activity
DKE43_07310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DKE43_07320	COG3872	metal-dependent enzyme
DKE43_07330	COG1752	Esterase of the alpha-beta hydrolase superfamily
DKE43_07335	COG1321	iron dependent repressor
DKE43_07340	COG0095	Lipoate-protein ligase
DKE43_07345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKE43_07350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DKE43_07355	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DKE43_07360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DKE43_07365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DKE43_07390	COG0681	Belongs to the peptidase S26 family
DKE43_07425	COG4970	Tfp pilus assembly protein FimT
DKE43_07430	COG4537	Required for transformation and DNA binding
DKE43_07435	COG1459	type II secretion system
DKE43_07440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DKE43_07450	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_07460	COG1393	Belongs to the ArsC family
DKE43_07470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE43_07485	COG0011	TIGRFAM Protein of
DKE43_07490	COG2814	Major facilitator Superfamily
DKE43_07500	COG2866	Carboxypeptidase
DKE43_07505	COG1368	sulfuric ester hydrolase activity
DKE43_07510	COG1940	carbohydrate kinase activity
DKE43_07515	COG4483	Protein conserved in bacteria
DKE43_07520	COG0705	Rhomboid family
DKE43_07520	COG0457	Tetratricopeptide repeat
DKE43_07525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DKE43_07530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DKE43_07545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DKE43_07550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DKE43_07555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DKE43_07560	COG0581	inorganic phosphate transmembrane transporter activity
DKE43_07565	COG0573	inorganic phosphate transmembrane transporter activity
DKE43_07570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DKE43_07580	COG0477	Major facilitator Superfamily
DKE43_07585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DKE43_07590	COG2839	Protein conserved in bacteria
DKE43_07595	COG5521	maltodextrose utilization protein MalA
DKE43_07600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE43_07605	COG1388	LysM domain
DKE43_07610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DKE43_07615	COG4709	membrane
DKE43_07620	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
DKE43_07625	COG1940	carbohydrate kinase activity
DKE43_07630	COG0735	belongs to the Fur family
DKE43_07635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKE43_07640	COG1121	(ABC) transporter
DKE43_07645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKE43_07655	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DKE43_07660	COG0513	Belongs to the DEAD box helicase family
DKE43_07670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DKE43_07675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DKE43_07680	COG2384	SAM-dependent methyltransferase
DKE43_07685	COG2010	Cytochrome c
DKE43_07690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DKE43_07695	COG0358	DNA primase activity
DKE43_07700	COG1671	Belongs to the UPF0178 family
DKE43_07705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DKE43_07710	COG0517	IMP dehydrogenase activity
DKE43_07715	COG0751	glycine-tRNA ligase activity
DKE43_07720	COG0752	glycyl-tRNA synthetase alpha subunit
DKE43_07725	COG1381	Involved in DNA repair and RecF pathway recombination
DKE43_07735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DKE43_07740	COG0295	cytidine deaminase activity
DKE43_07745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DKE43_07750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DKE43_07755	COG1480	7TM receptor with intracellular HD hydrolase
DKE43_07760	COG1702	phosphate starvation-inducible protein PhoH
DKE43_07765	COG0561	phosphatase activity
DKE43_07780	COG4864	UPF0365 protein
DKE43_07785	COG1030	water channel activity
DKE43_07790	COG1610	YqeY-like protein
DKE43_07795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DKE43_07800	COG1283	sodium-dependent phosphate transmembrane transporter activity
DKE43_07805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKE43_07810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKE43_07815	COG2264	protein methyltransferase activity
DKE43_07820	COG0484	heat shock protein binding
DKE43_07825	COG0443	Heat shock 70 kDa protein
DKE43_07830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DKE43_07835	COG1420	regulation of RNA biosynthetic process
DKE43_07840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DKE43_07845	COG0481	GTPase activity
DKE43_07855	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKE43_07860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
DKE43_07865	COG0268	Binds directly to 16S ribosomal RNA
DKE43_07870	COG1466	dna polymerase III delta subunit
DKE43_07880	COG0658	competence protein
DKE43_07880	COG2333	competence protein COMEC
DKE43_07885	COG2131	deaminase
DKE43_07890	COG1555	photosystem II stabilization
DKE43_07895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DKE43_07900	COG2226	methyltransferase
DKE43_07905	COG0799	negative regulation of ribosome biogenesis
DKE43_07910	COG1713	HD superfamily hydrolase involved in NAD metabolism
DKE43_07915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DKE43_07920	COG1534	Rna-binding protein
DKE43_07925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKE43_07930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DKE43_07935	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DKE43_07945	COG2755	lipolytic protein G-D-S-L family
DKE43_07950	COG0726	polysaccharide deacetylase
DKE43_07955	COG0457	Tetratricopeptide repeat
DKE43_07970	COG4221	oxidoreductase activity
DKE43_07975	COG0300	oxidoreductase activity
DKE43_07980	COG1902	pentaerythritol trinitrate reductase activity
DKE43_07985	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE43_07985	COG0596	Alpha beta hydrolase
DKE43_07990	COG1309	transcriptional regulator
DKE43_08000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKE43_08015	COG0726	polysaccharide deacetylase
DKE43_08050	COG1122	ATPase activity
DKE43_08070	COG2160	L-arabinose isomerase activity
DKE43_08085	COG1609	Transcriptional regulator
DKE43_08095	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DKE43_08100	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
DKE43_08105	COG1733	regulation of RNA biosynthetic process
DKE43_08130	COG3209	COG3209 Rhs family protein
DKE43_08135	COG2602	Beta-lactamase
DKE43_08140	COG1960	acyl-CoA dehydrogenase activity
DKE43_08145	COG1126	abc transporter atp-binding protein
DKE43_08150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_08155	COG0765	amino acid transport
DKE43_08165	COG3546	catalase activity
DKE43_08170	COG1063	alcohol dehydrogenase
DKE43_08180	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_08185	COG0842	Transport permease protein
DKE43_08190	COG1511	domain protein
DKE43_08190	COG0842	Transport permease protein
DKE43_08195	COG1131	(ABC) transporter
DKE43_08200	COG1063	alcohol dehydrogenase
DKE43_08205	COG2226	methyltransferase
DKE43_08225	COG0626	cystathionine gamma-synthase activity
DKE43_08230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE43_08235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DKE43_08240	COG2226	methyltransferase
DKE43_08255	COG0768	penicillin binding
DKE43_08260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DKE43_08265	COG0572	uridine kinase
DKE43_08285	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DKE43_08290	COG0183	Belongs to the thiolase family
DKE43_08295	COG0318	PFAM AMP-dependent synthetase and ligase
DKE43_08300	COG1268	BioY protein
DKE43_08305	COG3906	Belongs to the UPF0473 family
DKE43_08310	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DKE43_08315	COG4472	Bacterial protein of unknown function (DUF965)
DKE43_08320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DKE43_08325	COG0628	permease
DKE43_08330	COG1126	abc transporter atp-binding protein
DKE43_08335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_08340	COG0765	amino acid transport
DKE43_08345	COG0765	amino acid transport
DKE43_08360	COG3881	PFAM PRC-barrel domain
DKE43_08365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKE43_08370	COG0457	Tetratricopeptide repeat
DKE43_08375	COG0482	sulfurtransferase activity
DKE43_08380	COG1104	cysteine desulfurase activity
DKE43_08385	COG1959	2 iron, 2 sulfur cluster binding
DKE43_08390	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DKE43_08395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DKE43_08410	COG0124	histidyl-tRNA synthetase
DKE43_08415	COG4991	sh3 domain protein
DKE43_08415	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKE43_08415	COG3103	Sh3 type 3 domain protein
DKE43_08420	COG1490	D-aminoacyl-tRNA deacylase activity
DKE43_08425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DKE43_08430	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DKE43_08435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DKE43_08435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DKE43_08440	COG5416	Lipopolysaccharide assembly protein A domain
DKE43_08445	COG0490	domain, Protein
DKE43_08450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKE43_08450	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKE43_08460	COG2244	polysaccharide biosynthetic process
DKE43_08465	COG2323	membrane
DKE43_08475	COG1862	Preprotein translocase
DKE43_08480	COG0343	queuine tRNA-ribosyltransferase activity
DKE43_08485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DKE43_08495	COG2255	four-way junction helicase activity
DKE43_08500	COG0632	four-way junction helicase activity
DKE43_08510	COG2112	serine threonine protein kinase
DKE43_08520	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DKE43_08535	COG1388	LysM domain
DKE43_08535	COG1388	LysM domain
DKE43_08540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DKE43_08545	COG0157	Belongs to the NadC ModD family
DKE43_08550	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DKE43_08555	COG1104	cysteine desulfurase activity
DKE43_08560	COG1827	regulation of RNA biosynthetic process
DKE43_08565	COG0077	Prephenate dehydratase
DKE43_08570	COG4492	Belongs to the UPF0735 family
DKE43_08575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DKE43_08580	COG3290	protein histidine kinase activity
DKE43_08585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DKE43_08590	COG2868	ribosomal protein
DKE43_08595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DKE43_08600	COG1994	Peptidase M50
DKE43_08605	COG0739	heme binding
DKE43_08610	COG2894	cell division
DKE43_08615	COG0850	regulation of cytokinetic process
DKE43_08620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DKE43_08625	COG1792	Involved in formation and maintenance of cell shape
DKE43_08630	COG1077	Cell shape determining protein MreB Mrl
DKE43_08635	COG2003	Belongs to the UPF0758 family
DKE43_08640	COG0424	maF-like protein
DKE43_08655	COG0285	dihydrofolate synthase activity
DKE43_08660	COG0525	valine-tRNA ligase activity
DKE43_08670	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DKE43_08675	COG1388	LysM domain
DKE43_08680	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DKE43_08685	COG0113	porphobilinogen synthase activity
DKE43_08690	COG1587	Uroporphyrinogen-III synthase
DKE43_08695	COG0181	hydroxymethylbilane synthase activity
DKE43_08700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DKE43_08705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DKE43_08715	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DKE43_08720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DKE43_08725	COG0470	DNA polymerase III
DKE43_08725	COG1067	ATP-dependent peptidase activity
DKE43_08730	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DKE43_08735	COG0544	peptidyl-prolyl cis-trans isomerase activity
DKE43_08740	COG0457	Tetratricopeptide repeat
DKE43_08740	COG1477	protein flavinylation
DKE43_08745	COG0066	3-isopropylmalate dehydratase activity
DKE43_08750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DKE43_08755	COG0473	3-isopropylmalate dehydrogenase activity
DKE43_08760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKE43_08765	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DKE43_08770	COG0440	acetolactate synthase activity
DKE43_08775	COG0028	Belongs to the TPP enzyme family
DKE43_08780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DKE43_08785	COG2706	6-phosphogluconolactonase activity
DKE43_08790	COG3339	Conserved Protein
DKE43_08795	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DKE43_08800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKE43_08805	COG1696	Membrane protein involved in D-alanine export
DKE43_08810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKE43_08855	COG0622	Phosphoesterase
DKE43_08860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DKE43_08865	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DKE43_08870	COG5401	PFAM Sporulation and spore germination
DKE43_08875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKE43_08880	COG1846	Transcriptional regulator
DKE43_08885	COG2197	response regulator
DKE43_08890	COG2851	Citrate transporter
DKE43_08895	COG0583	DNA-binding transcription factor activity
DKE43_08900	COG2828	Protein conserved in bacteria
DKE43_08910	COG0824	Thioesterase
DKE43_08915	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DKE43_08920	COG1053	succinate dehydrogenase
DKE43_08925	COG2009	succinate dehydrogenase
DKE43_08930	COG1719	4-vinyl reductase, 4VR
DKE43_08935	COG0527	aspartate kinase activity
DKE43_08940	COG0322	excinuclease ABC activity
DKE43_08945	COG3118	belongs to the thioredoxin family
DKE43_08950	COG3534	alpha-L-arabinofuranosidase
DKE43_08955	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DKE43_08960	COG2086	electron transfer activity
DKE43_08965	COG1024	Enoyl-CoA hydratase
DKE43_08970	COG1309	transcriptional regulator
DKE43_08975	COG0318	PFAM AMP-dependent synthetase and ligase
DKE43_08985	COG3766	membrane
DKE43_08990	COG1193	negative regulation of DNA recombination
DKE43_08995	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DKE43_08995	COG1796	DNA polymerase
DKE43_09000	COG1286	toxin biosynthetic process
DKE43_09005	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DKE43_09010	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKE43_09015	COG0072	phenylalanine-tRNA ligase activity
DKE43_09015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE43_09020	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DKE43_09025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKE43_09035	COG1966	Carbon starvation protein
DKE43_09040	COG1363	Peptidase, m42
DKE43_09050	COG3326	Membrane
DKE43_09055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKE43_09060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKE43_09065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DKE43_09070	COG1346	cytolysis
DKE43_09080	COG3279	Response regulator of the LytR AlgR family
DKE43_09085	COG3275	phosphorelay sensor kinase activity
DKE43_09100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DKE43_09115	COG0398	Pfam SNARE associated Golgi protein
DKE43_09120	COG1484	DNA-dependent DNA replication
DKE43_09125	COG3611	Membrane attachment protein
DKE43_09130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DKE43_09140	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DKE43_09145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DKE43_09150	COG0237	dephospho-CoA kinase activity
DKE43_09155	COG1971	Probably functions as a manganese efflux pump
DKE43_09160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DKE43_09165	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKE43_09165	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKE43_09175	COG5002	protein histidine kinase activity
DKE43_09180	COG0745	RESPONSE REGULATOR receiver
DKE43_09185	COG0039	L-malate dehydrogenase activity
DKE43_09190	COG0538	isocitrate dehydrogenase activity
DKE43_09195	COG0372	Belongs to the citrate synthase family
DKE43_09200	COG2707	UPF0756 membrane protein
DKE43_09205	COG0628	permease
DKE43_09210	COG3030	protein affecting phage T7 exclusion by the F plasmid
DKE43_09220	COG0205	6-phosphofructokinase activity
DKE43_09225	COG0825	malonyl-CoA metabolic process
DKE43_09230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DKE43_09235	COG0281	malic enzyme
DKE43_09240	COG0587	DNA-directed DNA polymerase activity
DKE43_09260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DKE43_09270	COG4109	DRTGG domain
DKE43_09275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DKE43_09280	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_09285	COG0165	Argininosuccinate lyase
DKE43_09290	COG0137	argininosuccinate synthase activity
DKE43_09295	COG0521	Mo-molybdopterin cofactor biosynthetic process
DKE43_09300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DKE43_09305	COG0827	DNA restriction-modification system
DKE43_09310	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DKE43_09315	COG3874	Sporulation protein YtfJ
DKE43_09325	COG1714	RDD family
DKE43_09330	COG0616	signal peptide processing
DKE43_09335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKE43_09345	COG3239	Fatty acid desaturase
DKE43_09350	COG4585	Histidine kinase
DKE43_09355	COG2197	response regulator
DKE43_09360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_09365	COG0745	RESPONSE REGULATOR receiver
DKE43_09370	COG2205	protein histidine kinase activity
DKE43_09375	COG0772	Belongs to the SEDS family
DKE43_09380	COG1695	Transcriptional regulator
DKE43_09385	COG1136	(ABC) transporter
DKE43_09390	COG0577	efflux transmembrane transporter activity
DKE43_09395	COG0402	S-adenosylhomocysteine deaminase activity
DKE43_09400	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE43_09420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKE43_09430	COG0301	tRNA thio-modification
DKE43_09435	COG1104	cysteine desulfurase activity
DKE43_09440	COG1114	Component of the transport system for branched-chain amino acids
DKE43_09445	COG1114	Component of the transport system for branched-chain amino acids
DKE43_09450	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DKE43_09455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DKE43_09460	COG1309	transcriptional regulator
DKE43_09465	COG1956	GAF domain-containing protein
DKE43_09470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DKE43_09485	COG1335	isochorismatase
DKE43_09495	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DKE43_09500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DKE43_09505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKE43_09510	COG0454	-acetyltransferase
DKE43_09515	COG0517	IMP dehydrogenase activity
DKE43_09520	COG0123	including yeast histone deacetylase and acetoin utilization protein
DKE43_09525	COG1609	Transcriptional regulator
DKE43_09530	COG1605	Chorismate mutase
DKE43_09530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DKE43_09535	COG3118	belongs to the thioredoxin family
DKE43_09540	COG4980	gas vesicle protein
DKE43_09545	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DKE43_09550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKE43_09555	COG1674	ftsk spoiiie
DKE43_09560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE43_09565	COG4848	Belongs to the UPF0354 family
DKE43_09570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_09585	COG1363	Peptidase, m42
DKE43_09590	COG5584	Small secreted protein
DKE43_09595	COG0281	malic enzyme
DKE43_09600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE43_09605	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DKE43_09615	COG0510	thiamine kinase activity
DKE43_09620	COG1597	lipid kinase activity
DKE43_09630	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DKE43_09635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE43_09640	COG3340	Belongs to the peptidase S51 family
DKE43_09645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DKE43_09650	COG2252	PERMEase
DKE43_09655	COG1349	DNA-binding transcription factor activity
DKE43_09660	COG1187	pseudouridine synthase activity
DKE43_09665	COG2244	polysaccharide biosynthetic process
DKE43_09670	COG2081	HI0933 family
DKE43_09680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DKE43_09695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKE43_09700	COG5578	integral membrane protein
DKE43_09705	COG0673	inositol 2-dehydrogenase activity
DKE43_09710	COG1653	transport
DKE43_09715	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DKE43_09720	COG4209	transmembrane transport
DKE43_09725	COG2207	Transcriptional regulator
DKE43_09730	COG1733	regulation of RNA biosynthetic process
DKE43_09735	COG2814	Major facilitator Superfamily
DKE43_09740	COG0656	L-ascorbic acid biosynthetic process
DKE43_09745	COG1653	transport
DKE43_09750	COG0395	ABC-type sugar transport system, permease component
DKE43_09755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKE43_09760	COG1073	alpha beta
DKE43_09765	COG0495	leucyl-tRNA aminoacylation
DKE43_09775	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_09775	COG2202	Pas domain
DKE43_09780	COG2433	Pfam Transposase IS66
DKE43_09785	COG0577	efflux transmembrane transporter activity
DKE43_09790	COG1136	(ABC) transporter
DKE43_09800	COG1131	(ABC) transporter
DKE43_09805	COG1725	Transcriptional regulator
DKE43_09820	COG1242	4 iron, 4 sulfur cluster binding
DKE43_09825	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DKE43_09835	COG2267	carboxylic ester hydrolase activity
DKE43_09840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DKE43_09845	COG0367	asparagine synthase
DKE43_09850	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DKE43_09855	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
DKE43_09865	COG1506	peptidase
DKE43_09870	COG1233	COG1233 Phytoene dehydrogenase and related
DKE43_09890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DKE43_09895	COG1116	anion transmembrane transporter activity
DKE43_09900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKE43_09905	COG0494	nUDIX hydrolase
DKE43_09910	COG2310	stress, protein
DKE43_09930	COG4824	toxin secretion phage lysis holin
DKE43_09940	COG0783	Belongs to the Dps family
DKE43_09955	COG1854	S-ribosylhomocysteine lyase activity
DKE43_09960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DKE43_09965	COG0288	reversible hydration of carbon dioxide
DKE43_09970	COG3443	Belongs to the bacterial solute-binding protein 9 family
DKE43_09970	COG0803	Belongs to the bacterial solute-binding protein 9 family
DKE43_09975	COG0254	rRNA binding
DKE43_09985	COG1271	oxidase subunit
DKE43_09990	COG1294	oxidase, subunit
DKE43_10005	COG4948	Mandelate Racemase Muconate Lactonizing
DKE43_10010	COG0318	PFAM AMP-dependent synthetase and ligase
DKE43_10015	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DKE43_10020	COG0596	Alpha beta hydrolase
DKE43_10025	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DKE43_10030	COG1169	isochorismate synthase
DKE43_10035	COG1575	Belongs to the MenA family. Type 1 subfamily
DKE43_10040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKE43_10170	COG3859	Proton-coupled thiamine transporter YuaJ
DKE43_10180	COG1247	-acetyltransferase
DKE43_10185	COG3339	Conserved Protein
DKE43_10190	COG0772	Belongs to the SEDS family
DKE43_10195	COG0772	Belongs to the SEDS family
DKE43_10205	COG2268	Band 7 protein
DKE43_10210	COG1585	Membrane protein implicated in regulation of membrane protease activity
DKE43_10215	COG2318	DinB family
DKE43_10220	COG1454	alcohol dehydrogenase
DKE43_10230	COG1510	regulation of RNA biosynthetic process
DKE43_10245	COG5632	N-Acetylmuramoyl-L-alanine amidase
DKE43_10245	COG3409	Peptidoglycan-binding domain 1 protein
DKE43_10295	COG3778	Protein conserved in bacteria
DKE43_10300	COG3299	homolog of phage Mu protein gp47
DKE43_10305	COG3628	GPW Gp25 family protein
DKE43_10315	COG4193	domain, Protein
DKE43_10320	COG1652	LysM domain
DKE43_10325	COG3953	SLT domain
DKE43_10325	COG5280	Phage tail tape measure protein TP901
DKE43_10325	COG3953	SLT domain
DKE43_10325	COG5280	Phage tail tape measure protein TP901
DKE43_10380	COG4653	Phage capsid family
DKE43_10385	COG0338	D12 class N6 adenine-specific DNA methyltransferase
DKE43_10390	COG5518	Phage portal protein
DKE43_10395	COG1783	phage Terminase large subunit
DKE43_10400	COG5484	DNA packaging
DKE43_10405	COG1595	DNA-templated transcription, initiation
DKE43_10415	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
DKE43_10430	COG1396	sequence-specific DNA binding
DKE43_10440	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DKE43_10455	COG0628	permease
DKE43_10470	COG0673	inositol 2-dehydrogenase activity
DKE43_10475	COG0693	protein deglycase activity
DKE43_10480	COG0840	transmembrane signaling receptor activity
DKE43_10485	COG0840	transmembrane signaling receptor activity
DKE43_10490	COG0840	transmembrane signaling receptor activity
DKE43_10495	COG0840	transmembrane signaling receptor activity
DKE43_10510	COG2070	2-Nitropropane dioxygenase
DKE43_10515	COG0432	Pfam Uncharacterised protein family UPF0047
DKE43_10520	COG1253	flavin adenine dinucleotide binding
DKE43_10525	COG2738	Putative neutral zinc metallopeptidase
DKE43_10535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DKE43_10550	COG0166	Belongs to the GPI family
DKE43_10555	COG1979	alcohol dehydrogenase
DKE43_10560	COG1979	alcohol dehydrogenase
DKE43_10565	COG2155	Conserved Protein
DKE43_10570	COG1098	S1 RNA binding domain
DKE43_10575	COG0436	Aminotransferase
DKE43_10580	COG1522	sequence-specific DNA binding
DKE43_10585	COG2267	carboxylic ester hydrolase activity
DKE43_10595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DKE43_10600	COG2205	protein histidine kinase activity
DKE43_10615	COG5018	Exonuclease
DKE43_10620	COG2814	Major facilitator Superfamily
DKE43_10625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKE43_10630	COG3011	Protein conserved in bacteria
DKE43_10645	COG3290	protein histidine kinase activity
DKE43_10650	COG4565	transcriptional regulatory protein
DKE43_10675	COG3493	citrate carrier protein
DKE43_10685	COG2111	Na H antiporter
DKE43_10685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DKE43_10690	COG2111	Na H antiporter
DKE43_10695	COG1006	Multisubunit Na H antiporter MnhC subunit
DKE43_10700	COG0651	ATP synthesis coupled electron transport
DKE43_10705	COG1863	multisubunit Na H antiporter MnhE subunit
DKE43_10710	COG2212	antiporter activity
DKE43_10715	COG1320	monovalent cation:proton antiporter activity
DKE43_10720	COG2050	protein possibly involved in aromatic compounds catabolism
DKE43_10725	COG2197	response regulator
DKE43_10730	COG4585	Histidine kinase
DKE43_10740	COG0142	geranyltranstransferase activity
DKE43_10755	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DKE43_10760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DKE43_10765	COG1335	isochorismatase
DKE43_10770	COG5506	Protein of unknown function (DUF1694)
DKE43_10790	COG0628	permease
DKE43_10805	COG1418	mRNA catabolic process
DKE43_10810	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_10820	COG1511	domain protein
DKE43_10825	COG1674	ftsk spoiiie
DKE43_10825	COG0433	COG0433 Predicted ATPase
DKE43_10830	COG4499	WXG100 protein secretion system (Wss), protein YukC
DKE43_10835	COG5417	Belongs to the EsaB family
DKE43_10840	COG4842	Belongs to the WXG100 family
DKE43_10845	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DKE43_10845	COG2508	Transcriptional regulator
DKE43_10850	COG0686	Belongs to the AlaDH PNT family
DKE43_10855	COG1268	BioY protein
DKE43_10860	COG4326	sporulation control protein
DKE43_10865	COG2056	Na+-H+ antiporter family
DKE43_10870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DKE43_10875	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DKE43_10880	COG3584	3D domain protein
DKE43_10890	COG1252	NADH dehydrogenase
DKE43_10895	COG0492	ferredoxin-NADP+ reductase activity
DKE43_10910	COG0316	Belongs to the HesB IscA family
DKE43_10915	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DKE43_10920	COG4844	belongs to the
DKE43_10925	COG1252	NADH dehydrogenase
DKE43_10935	COG4837	Protein of unknown function (DUF1462)
DKE43_10940	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DKE43_10950	COG1506	peptidase
DKE43_10950	COG0823	Involved in the tonB-independent uptake of proteins
DKE43_10950	COG4946	Tricorn protease homolog
DKE43_10955	COG0083	homoserine kinase activity
DKE43_10960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DKE43_10965	COG0460	homoserine dehydrogenase
DKE43_10975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKE43_10980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DKE43_10985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DKE43_10990	COG0647	UMP catabolic process
DKE43_10995	COG2445	Protein of unknown function DUF86
DKE43_11000	COG4470	Protein conserved in bacteria
DKE43_11010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKE43_11015	COG0739	heme binding
DKE43_11025	COG3377	Domain of unknown function (DUF1805)
DKE43_11030	COG0737	Belongs to the 5'-nucleotidase family
DKE43_11035	COG1801	Protein of unknown function DUF72
DKE43_11040	COG2508	Transcriptional regulator
DKE43_11050	COG2814	Major facilitator Superfamily
DKE43_11055	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DKE43_11070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_11075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_11080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_11095	COG5002	protein histidine kinase activity
DKE43_11095	COG0642	Histidine kinase
DKE43_11100	COG0745	RESPONSE REGULATOR receiver
DKE43_11105	COG2311	Membrane
DKE43_11115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DKE43_11125	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DKE43_11150	COG0719	Fe-S assembly protein
DKE43_11155	COG0822	iron-sulfur transferase activity
DKE43_11160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DKE43_11165	COG0719	Fe-S assembly protein
DKE43_11170	COG0396	ATPase activity
DKE43_11175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKE43_11180	COG1464	Belongs to the NlpA lipoprotein family
DKE43_11185	COG2011	ABC-type metal ion transport system permease component
DKE43_11190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKE43_11200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_11205	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DKE43_11215	COG0509	glycine decarboxylation via glycine cleavage system
DKE43_11220	COG1393	Belongs to the ArsC family
DKE43_11225	COG1960	acyl-CoA dehydrogenase activity
DKE43_11230	COG0183	Belongs to the thiolase family
DKE43_11235	COG1024	Enoyl-CoA hydratase
DKE43_11235	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKE43_11250	COG5577	PFAM Coat F domain
DKE43_11270	COG1120	ATPase activity
DKE43_11280	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_11285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKE43_11290	COG0745	RESPONSE REGULATOR receiver
DKE43_11295	COG2770	Histidine kinase
DKE43_11295	COG2205	protein histidine kinase activity
DKE43_11300	COG1309	transcriptional regulator
DKE43_11305	COG0114	fumarate hydratase activity
DKE43_11315	COG0697	spore germination
DKE43_11320	COG0814	amino acid
DKE43_11335	COG2197	response regulator
DKE43_11340	COG4585	Histidine kinase
DKE43_11345	COG4758	membrane
DKE43_11355	COG1842	Phage shock protein A
DKE43_11360	COG4758	membrane
DKE43_11365	COG2096	Adenosyltransferase
DKE43_11370	COG1120	ATPase activity
DKE43_11375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_11380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_11390	COG2721	sulfolactate sulfo-lyase activity
DKE43_11395	COG0246	Mannitol dehydrogenase
DKE43_11400	COG1609	Transcriptional regulator
DKE43_11405	COG1904	glucuronate isomerase
DKE43_11410	COG2205	protein histidine kinase activity
DKE43_11415	COG0745	RESPONSE REGULATOR receiver
DKE43_11420	COG1120	ATPase activity
DKE43_11425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_11430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_11435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_11440	COG0531	amino acid
DKE43_11460	COG1988	membrane-bound metal-dependent
DKE43_11465	COG1368	sulfuric ester hydrolase activity
DKE43_11470	COG0725	ABC transporter, periplasmic molybdate-binding protein
DKE43_11475	COG4149	molybdate abc transporter
DKE43_11480	COG0656	L-ascorbic acid biosynthetic process
DKE43_11485	COG1940	carbohydrate kinase activity
DKE43_11490	COG0025	NhaP-type Na H and K H
DKE43_11500	COG2860	membrane
DKE43_11505	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DKE43_11510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DKE43_11515	COG2217	Heavy metal translocating P-type atpase
DKE43_11520	COG1121	(ABC) transporter
DKE43_11525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKE43_11530	COG0803	Belongs to the bacterial solute-binding protein 9 family
DKE43_11540	COG3226	Transcriptional regulator
DKE43_11545	COG0784	Response regulator, receiver
DKE43_11550	COG4191	Histidine kinase
DKE43_11555	COG1027	Aspartate ammonia-lyase
DKE43_11565	COG2217	Heavy metal translocating P-type atpase
DKE43_11570	COG2608	mercury ion transmembrane transporter activity
DKE43_11575	COG1937	Protein conserved in bacteria
DKE43_11585	COG3706	GGDEF domain
DKE43_11585	COG0745	RESPONSE REGULATOR receiver
DKE43_11595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKE43_11610	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DKE43_11615	COG0557	exoribonuclease II activity
DKE43_11620	COG1647	Serine aminopeptidase, S33
DKE43_11625	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DKE43_11630	COG2002	toxin-antitoxin pair type II binding
DKE43_11635	COG1476	TRANSCRIPTIONal
DKE43_11640	COG1396	sequence-specific DNA binding
DKE43_11645	COG1396	sequence-specific DNA binding
DKE43_11650	COG1733	regulation of RNA biosynthetic process
DKE43_11655	COG1174	glycine betaine transport
DKE43_11660	COG1732	Glycine betaine
DKE43_11665	COG1174	glycine betaine transport
DKE43_11670	COG1125	glycine betaine transport
DKE43_11670	COG0517	IMP dehydrogenase activity
DKE43_11675	COG1510	regulation of RNA biosynthetic process
DKE43_11680	COG2095	MarC family integral membrane protein
DKE43_11690	COG0456	acetyltransferase
DKE43_11710	COG1131	(ABC) transporter
DKE43_11720	COG0148	phosphopyruvate hydratase activity
DKE43_11725	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DKE43_11730	COG0149	triose-phosphate isomerase activity
DKE43_11735	COG0126	phosphoglycerate kinase activity
DKE43_11740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DKE43_11745	COG2390	Transcriptional regulator
DKE43_11750	COG0833	amino acid
DKE43_11755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKE43_11760	COG3829	transcription factor binding
DKE43_11765	COG2186	Transcriptional regulator
DKE43_11770	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DKE43_11780	COG0534	Mate efflux family protein
DKE43_11785	COG4608	Belongs to the ABC transporter superfamily
DKE43_11790	COG0444	Belongs to the ABC transporter superfamily
DKE43_11795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKE43_11800	COG0601	transmembrane transport
DKE43_11805	COG0747	negative chemotaxis
DKE43_11810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DKE43_11815	COG0110	maltose O-acetyltransferase activity
DKE43_11820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DKE43_11825	COG2244	polysaccharide biosynthetic process
DKE43_11830	COG5039	Polysaccharide pyruvyl transferase
DKE43_11835	COG1216	Glycosyl transferase, family 2
DKE43_11845	COG0438	transferase activity, transferring glycosyl groups
DKE43_11850	COG1215	transferase activity, transferring glycosyl groups
DKE43_11855	COG0438	transferase activity, transferring glycosyl groups
DKE43_11860	COG1086	Polysaccharide biosynthesis protein
DKE43_11865	COG0489	protein tyrosine kinase activity
DKE43_11870	COG3944	biosynthesis protein
DKE43_11875	COG1396	sequence-specific DNA binding
DKE43_11885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_11890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_11895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKE43_11900	COG0726	polysaccharide deacetylase
DKE43_11910	COG1124	(ABC) transporter
DKE43_11925	COG0601	transmembrane transport
DKE43_11930	COG0747	negative chemotaxis
DKE43_11935	COG1819	glycosyl
DKE43_11940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_11950	COG0740	serine-type endopeptidase activity
DKE43_11955	COG1611	Belongs to the LOG family
DKE43_11960	COG1694	Mazg nucleotide pyrophosphohydrolase
DKE43_11965	COG0659	secondary active sulfate transmembrane transporter activity
DKE43_11970	COG0288	reversible hydration of carbon dioxide
DKE43_11975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKE43_11985	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DKE43_11990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_11995	COG1481	regulation of sporulation
DKE43_12000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DKE43_12005	COG1660	Displays ATPase and GTPase activities
DKE43_12010	COG1051	belongs to the nudix hydrolase family
DKE43_12015	COG0492	ferredoxin-NADP+ reductase activity
DKE43_12020	COG0791	NLP P60 protein
DKE43_12020	COG3883	PFAM NLP P60 protein
DKE43_12025	COG0457	Tetratricopeptide repeat
DKE43_12030	COG0140	phosphoribosyl-ATP diphosphatase activity
DKE43_12030	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DKE43_12035	COG0107	imidazoleglycerol-phosphate synthase activity
DKE43_12040	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DKE43_12045	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKE43_12050	COG0131	Imidazoleglycerol-phosphate dehydratase
DKE43_12055	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DKE43_12060	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DKE43_12065	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DKE43_12070	COG4990	cell redox homeostasis
DKE43_12075	COG2910	NAD(P)H-binding
DKE43_12080	COG1959	2 iron, 2 sulfur cluster binding
DKE43_12085	COG0110	maltose O-acetyltransferase activity
DKE43_12090	COG0546	phosphoglycolate phosphatase activity
DKE43_12095	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DKE43_12105	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DKE43_12110	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DKE43_12115	COG0363	glucosamine-6-phosphate deaminase activity
DKE43_12125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DKE43_12130	COG1950	PFAM Membrane protein of
DKE43_12135	COG1983	PspC domain protein
DKE43_12140	COG3595	metallopeptidase activity
DKE43_12155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DKE43_12165	COG4897	Protein conserved in bacteria
DKE43_12175	COG3848	Pyruvate phosphate dikinase
DKE43_12175	COG0574	Belongs to the PEP-utilizing enzyme family
DKE43_12180	COG1309	transcriptional regulator
DKE43_12185	COG2814	Major facilitator Superfamily
DKE43_12195	COG0745	RESPONSE REGULATOR receiver
DKE43_12200	COG5002	protein histidine kinase activity
DKE43_12205	COG1113	amino acid transport
DKE43_12210	COG0778	Nitroreductase
DKE43_12215	COG1733	regulation of RNA biosynthetic process
DKE43_12220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKE43_12230	COG3409	Peptidoglycan-binding domain 1 protein
DKE43_12230	COG0793	Belongs to the peptidase S41A family
DKE43_12235	COG0730	response to heat
DKE43_12240	COG0791	NLP P60 protein
DKE43_12240	COG3883	PFAM NLP P60 protein
DKE43_12245	COG2177	Part of the ABC transporter FtsEX involved in
DKE43_12250	COG2884	Cell division ATP-binding protein ftsE
DKE43_12255	COG2010	Cytochrome c
DKE43_12260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKE43_12280	COG0653	protein targeting
DKE43_12285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DKE43_12290	COG0840	transmembrane signaling receptor activity
DKE43_12305	COG1516	flagellar protein fliS
DKE43_12310	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DKE43_12315	COG1334	flagellar protein FlaG
DKE43_12320	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DKE43_12325	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DKE43_12335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DKE43_12340	COG1256	bacterial-type flagellum assembly
DKE43_12340	COG4786	Flagellar basal body rod
DKE43_12345	COG3418	PFAM FlgN family protein
DKE43_12360	COG1040	competence protein
DKE43_12370	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DKE43_12375	COG1307	EDD domain protein, DegV family
DKE43_12380	COG2197	response regulator
DKE43_12385	COG4585	Histidine kinase
DKE43_12390	COG1739	Uncharacterized protein family UPF0029
DKE43_12395	COG1316	TRANSCRIPTIONal
DKE43_12400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKE43_12405	COG0438	transferase activity, transferring glycosyl groups
DKE43_12410	COG1215	transferase activity, transferring glycosyl groups
DKE43_12415	COG3206	protein involved in exopolysaccharide biosynthesis
DKE43_12420	COG3307	-O-antigen
DKE43_12425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKE43_12430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DKE43_12435	COG0297	glycogen (starch) synthase activity
DKE43_12435	COG0438	transferase activity, transferring glycosyl groups
DKE43_12440	COG2244	polysaccharide biosynthetic process
DKE43_12455	COG2247	cell wall binding repeat
DKE43_12455	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKE43_12460	COG2385	sporulation resulting in formation of a cellular spore
DKE43_12460	COG2247	cell wall binding repeat
DKE43_12470	COG1316	TRANSCRIPTIONal
DKE43_12475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DKE43_12480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DKE43_12485	COG1134	teichoic acid transport
DKE43_12490	COG1682	transport, permease protein
DKE43_12500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DKE43_12510	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DKE43_12515	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
DKE43_12520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DKE43_12530	COG4193	domain, Protein
DKE43_12535	COG1482	cell wall glycoprotein biosynthetic process
DKE43_12545	COG1175	transmembrane transport
DKE43_12550	COG1653	transport
DKE43_12555	COG2197	response regulator
DKE43_12560	COG2972	Histidine kinase
DKE43_12570	COG0454	-acetyltransferase
DKE43_12575	COG0800	Aldolase
DKE43_12580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKE43_12585	COG1609	Transcriptional regulator
DKE43_12590	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
DKE43_12595	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_12600	COG0697	spore germination
DKE43_12605	COG0814	amino acid
DKE43_12620	COG2814	Major facilitator Superfamily
DKE43_12625	COG1316	TRANSCRIPTIONal
DKE43_12635	COG0561	phosphatase activity
DKE43_12640	COG0791	NLP P60 protein
DKE43_12645	COG2843	Capsule synthesis protein
DKE43_12655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DKE43_12660	COG0697	spore germination
DKE43_12675	COG1609	Transcriptional regulator
DKE43_12680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKE43_12685	COG1869	D-ribose catabolic process
DKE43_12690	COG1129	ABC transporter
DKE43_12695	COG1172	Belongs to the binding-protein-dependent transport system permease family
DKE43_12700	COG1879	ABC-type sugar transport system periplasmic component
DKE43_12705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKE43_12710	COG0583	DNA-binding transcription factor activity
DKE43_12715	COG0028	Belongs to the TPP enzyme family
DKE43_12720	COG3527	Alpha-acetolactate decarboxylase
DKE43_12725	COG1522	sequence-specific DNA binding
DKE43_12730	COG2059	Chromate
DKE43_12735	COG2059	Chromate
DKE43_12740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DKE43_12745	COG4715	Zinc finger, swim domain protein
DKE43_12750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DKE43_12755	COG2202	Pas domain
DKE43_12755	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_12760	COG0561	phosphatase activity
DKE43_12775	COG1970	mechanosensitive ion channel activity
DKE43_12780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DKE43_12785	COG0457	Tetratricopeptide repeat
DKE43_12790	COG4786	Flagellar basal body rod
DKE43_12795	COG4786	Flagellar basal body rod
DKE43_12800	COG1077	Cell shape determining protein MreB Mrl
DKE43_12805	COG1609	Transcriptional regulator
DKE43_12810	COG1846	Transcriptional regulator
DKE43_12815	COG2814	Major facilitator Superfamily
DKE43_12820	COG0671	phosphoesterase, PA-phosphatase related
DKE43_12825	COG0477	Major facilitator Superfamily
DKE43_12830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_12835	COG0765	amino acid transport
DKE43_12840	COG1126	abc transporter atp-binding protein
DKE43_12850	COG0004	ammonium transporteR
DKE43_12855	COG0347	Belongs to the P(II) protein family
DKE43_12860	COG0739	heme binding
DKE43_12865	COG1247	-acetyltransferase
DKE43_12905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DKE43_12910	COG0523	cobalamin synthesis protein
DKE43_12915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DKE43_12920	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DKE43_12925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DKE43_12935	COG0243	molybdopterin cofactor binding
DKE43_12940	COG2304	oxidoreductase activity
DKE43_12945	COG2304	oxidoreductase activity
DKE43_12950	COG2385	sporulation resulting in formation of a cellular spore
DKE43_12955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DKE43_12965	COG4836	Membrane
DKE43_12975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DKE43_12980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DKE43_12985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DKE43_12990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DKE43_12995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKE43_13000	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DKE43_13005	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKE43_13010	COG0356	it plays a direct role in the translocation of protons across the membrane
DKE43_13020	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DKE43_13025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DKE43_13030	COG4475	Protein of unknown function (DUF436)
DKE43_13035	COG0698	ribose 5-phosphate isomerase
DKE43_13040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DKE43_13045	COG1971	Probably functions as a manganese efflux pump
DKE43_13050	COG0009	L-threonylcarbamoyladenylate synthase
DKE43_13055	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DKE43_13070	COG2890	protein-(glutamine-N5) methyltransferase activity
DKE43_13075	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DKE43_13080	COG0789	Transcriptional regulator
DKE43_13085	COG0679	Auxin Efflux Carrier
DKE43_13090	COG0281	malic enzyme
DKE43_13095	COG1435	thymidine kinase activity
DKE43_13100	COG0254	rRNA binding
DKE43_13105	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DKE43_13110	COG1494	fructose-1,6-bisphosphatase
DKE43_13115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DKE43_13120	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DKE43_13125	COG0191	fructose-bisphosphate aldolase activity
DKE43_13130	COG2204	response regulator
DKE43_13135	COG4821	SIS domain
DKE43_13140	COG0504	CTP synthase activity
DKE43_13145	COG3343	RNA polymerase activity
DKE43_13155	COG1960	acyl-CoA dehydrogenase activity
DKE43_13160	COG1960	acyl-CoA dehydrogenase activity
DKE43_13165	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKE43_13170	COG0183	Belongs to the thiolase family
DKE43_13175	COG2181	nitrate reductase activity
DKE43_13175	COG0247	lactate metabolic process
DKE43_13180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE43_13185	COG4294	response to UV
DKE43_13195	COG1619	proteins homologs of microcin C7 resistance protein MccF
DKE43_13200	COG1132	(ABC) transporter
DKE43_13205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKE43_13210	COG1619	proteins homologs of microcin C7 resistance protein MccF
DKE43_13215	COG0018	arginyl-trna synthetase
DKE43_13220	COG4506	Protein conserved in bacteria
DKE43_13235	COG0010	Belongs to the arginase family
DKE43_13240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DKE43_13245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKE43_13255	COG1994	Peptidase M50
DKE43_13260	COG1942	4-Oxalocrotonate Tautomerase
DKE43_13270	COG3465	dGTPase activity
DKE43_13275	COG1078	dGTPase activity
DKE43_13280	COG4844	belongs to the
DKE43_13315	COG5444	nuclease activity
DKE43_13330	COG0280	phosphate acetyltransferase
DKE43_13380	COG1396	sequence-specific DNA binding
DKE43_13385	COG3620	sequence-specific DNA binding
DKE43_13400	COG1073	alpha beta
DKE43_13410	COG1522	sequence-specific DNA binding
DKE43_13415	COG2814	Major facilitator Superfamily
DKE43_13420	COG0077	Prephenate dehydratase
DKE43_13425	COG1917	Cupin 2, conserved barrel domain protein
DKE43_13430	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_13435	COG0151	Belongs to the GarS family
DKE43_13440	COG0436	Aminotransferase
DKE43_13445	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_13450	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DKE43_13455	COG1091	dTDP-4-dehydrorhamnose reductase activity
DKE43_13460	COG1088	dTDP-glucose 4,6-dehydratase activity
DKE43_13465	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DKE43_13470	COG3980	spore coat polysaccharide biosynthesis protein
DKE43_13475	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DKE43_13480	COG2089	acid synthase
DKE43_13485	COG0456	acetyltransferase
DKE43_13490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DKE43_13495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
DKE43_13500	COG0463	Glycosyl transferase, family 2
DKE43_13520	COG2363	Small membrane protein
DKE43_13525	COG2233	PERMEase
DKE43_13535	COG1012	belongs to the aldehyde dehydrogenase family
DKE43_13540	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DKE43_13545	COG1216	Glycosyl transferase, family 2
DKE43_13555	COG0351	phosphomethylpyrimidine kinase
DKE43_13575	COG1621	beta-fructofuranosidase activity
DKE43_13580	COG1263	PTS System
DKE43_13580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_13585	COG3711	transcriptional antiterminator
DKE43_13595	COG1404	Belongs to the peptidase S8 family
DKE43_13605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE43_13610	COG0778	Nitroreductase
DKE43_13615	COG0772	Belongs to the SEDS family
DKE43_13625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DKE43_13630	COG1845	cytochrome c oxidase, subunit III
DKE43_13635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DKE43_13640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DKE43_13650	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DKE43_13655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DKE43_13660	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DKE43_13675	COG2246	polysaccharide biosynthetic process
DKE43_13695	COG3162	membrane
DKE43_13700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE43_13715	COG0352	thiamine-phosphate diphosphorylase activity
DKE43_13720	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DKE43_13725	COG0583	DNA-binding transcription factor activity
DKE43_13735	COG1346	cytolysis
DKE43_13740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DKE43_13745	COG0346	lactoylglutathione lyase activity
DKE43_13755	COG0765	amino acid transport
DKE43_13760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_13770	COG0457	Tetratricopeptide repeat
DKE43_13775	COG2357	RelA SpoT domain protein
DKE43_13780	COG1172	Belongs to the binding-protein-dependent transport system permease family
DKE43_13785	COG1129	ABC transporter
DKE43_13795	COG3420	alginic acid biosynthetic process
DKE43_13800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DKE43_13815	COG1486	melibiose metabolic process
DKE43_13820	COG1447	Phosphotransferase system cellobiose-specific component IIA
DKE43_13825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKE43_13830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKE43_13835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_13835	COG3711	transcriptional antiterminator
DKE43_13850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DKE43_13865	COG1595	DNA-templated transcription, initiation
DKE43_13870	COG3866	Pectate lyase
DKE43_13875	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DKE43_13880	COG4988	ABC transporter
DKE43_13885	COG1294	oxidase, subunit
DKE43_13890	COG1271	oxidase subunit
DKE43_13910	COG4509	Sortase family
DKE43_13935	COG5386	Cell surface protein
DKE43_13940	COG5386	Cell surface protein
DKE43_13945	COG1733	regulation of RNA biosynthetic process
DKE43_13950	COG2514	catechol 2,3-dioxygenase activity
DKE43_13955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKE43_13955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKE43_13960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DKE43_13960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DKE43_13965	COG0346	lactoylglutathione lyase activity
DKE43_13970	COG0726	polysaccharide deacetylase
DKE43_13975	COG1447	Phosphotransferase system cellobiose-specific component IIA
DKE43_13980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKE43_13985	COG2723	6-phospho-beta-galactosidase activity
DKE43_13995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DKE43_14000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_14000	COG3711	transcriptional antiterminator
DKE43_14025	COG1757	Na H antiporter
DKE43_14030	COG1027	Aspartate ammonia-lyase
DKE43_14035	COG0252	asparaginase activity
DKE43_14040	COG1396	sequence-specific DNA binding
DKE43_14065	COG4842	Belongs to the WXG100 family
DKE43_14070	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKE43_14085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DKE43_14090	COG2723	6-phospho-beta-galactosidase activity
DKE43_14095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_14095	COG1263	PTS System
DKE43_14095	COG2190	(PTS) system
DKE43_14100	COG3711	transcriptional antiterminator
DKE43_14105	COG3878	Protein conserved in bacteria
DKE43_14115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DKE43_14120	COG1122	ATPase activity
DKE43_14125	COG4721	ABC-type cobalt transport system, permease component
DKE43_14130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DKE43_14160	COG3291	Pkd domain containing protein
DKE43_14160	COG4412	M6 family metalloprotease domain protein
DKE43_14165	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DKE43_14170	COG0778	Nitroreductase
DKE43_14175	COG1846	Transcriptional regulator
DKE43_14180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DKE43_14185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DKE43_14190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DKE43_14195	COG2390	Transcriptional regulator
DKE43_14205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DKE43_14205	COG2755	lipolytic protein G-D-S-L family
DKE43_14225	COG0561	phosphatase activity
DKE43_14230	COG0789	Transcriptional regulator
DKE43_14235	COG0673	inositol 2-dehydrogenase activity
DKE43_14240	COG0840	transmembrane signaling receptor activity
DKE43_14245	COG1113	amino acid transport
DKE43_14250	COG4335	DNA alkylation repair
DKE43_14260	COG1070	Carbohydrate kinase
DKE43_14265	COG1737	Transcriptional regulator
DKE43_14285	COG0583	DNA-binding transcription factor activity
DKE43_14290	COG1609	Transcriptional regulator
DKE43_14295	COG2182	Extracellular solute-binding protein
DKE43_14300	COG1175	transmembrane transport
DKE43_14305	COG3833	ABC-type maltose transport systems, permease component
DKE43_14315	COG1874	Beta-galactosidase
DKE43_14320	COG2851	Citrate transporter
DKE43_14335	COG1131	(ABC) transporter
DKE43_14340	COG2824	Alkylphosphonate utilization operon protein PhnA
DKE43_14345	COG1929	Belongs to the glycerate kinase type-1 family
DKE43_14350	COG2610	gluconate transmembrane transporter activity
DKE43_14355	COG3835	regulator
DKE43_14360	COG1309	transcriptional regulator
DKE43_14365	COG2814	Major facilitator Superfamily
DKE43_14375	COG1136	(ABC) transporter
DKE43_14385	COG0457	Tetratricopeptide repeat
DKE43_14390	COG3711	transcriptional antiterminator
DKE43_14395	COG2723	6-phospho-beta-galactosidase activity
DKE43_14400	COG2190	(PTS) system
DKE43_14400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_14400	COG1263	PTS System
DKE43_14435	COG1113	amino acid transport
DKE43_14445	COG2814	Major facilitator Superfamily
DKE43_14450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKE43_14455	COG2814	Major facilitator Superfamily
DKE43_14470	COG5444	nuclease activity
DKE43_14485	COG2723	6-phospho-beta-galactosidase activity
DKE43_14495	COG2188	Transcriptional regulator
DKE43_14520	COG1131	(ABC) transporter
DKE43_14525	COG1396	sequence-specific DNA binding
DKE43_14530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE43_14550	COG1404	Belongs to the peptidase S8 family
DKE43_14560	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DKE43_14570	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DKE43_14580	COG4720	Psort location CytoplasmicMembrane, score
DKE43_14600	COG0456	acetyltransferase
DKE43_14605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKE43_14610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DKE43_14615	COG4853	Protein conserved in bacteria
DKE43_14620	COG4863	YycH protein
DKE43_14625	COG5002	protein histidine kinase activity
DKE43_14630	COG0745	RESPONSE REGULATOR receiver
DKE43_14655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_14665	COG2311	Membrane
DKE43_14670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DKE43_14675	COG1309	transcriptional regulator
DKE43_14680	COG2124	cytochrome p450
DKE43_14685	COG0346	lactoylglutathione lyase activity
DKE43_14690	COG0305	Participates in initiation and elongation during chromosome replication
DKE43_14705	COG2819	hydrolase of the alpha beta superfamily
DKE43_14710	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_14715	COG1169	isochorismate synthase
DKE43_14720	COG1021	2,3-dihydroxybenzoate-AMP ligase
DKE43_14725	COG1535	isochorismatase
DKE43_14725	COG3433	isochorismatase activity
DKE43_14730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKE43_14735	COG3251	PFAM MbtH domain protein
DKE43_14740	COG2207	Transcriptional regulator
DKE43_14740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_14745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKE43_14750	COG2819	hydrolase of the alpha beta superfamily
DKE43_14755	COG3093	addiction module antidote protein HigA
DKE43_14760	COG2807	transmembrane transport
DKE43_14765	COG0359	binds to the 23S rRNA
DKE43_14770	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DKE43_14775	COG4241	membrane
DKE43_14780	COG1227	inorganic diphosphatase activity
DKE43_14790	COG1595	DNA-templated transcription, initiation
DKE43_14800	COG0753	catalase activity
DKE43_14805	COG0655	NAD(P)H dehydrogenase (quinone) activity
DKE43_14810	COG0400	carboxylic ester hydrolase activity
DKE43_14815	COG0346	lactoylglutathione lyase activity
DKE43_14820	COG1174	glycine betaine transport
DKE43_14825	COG1125	glycine betaine transport
DKE43_14825	COG0517	IMP dehydrogenase activity
DKE43_14830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DKE43_14835	COG0629	single-stranded DNA binding
DKE43_14840	COG0360	Binds together with S18 to 16S ribosomal RNA
DKE43_14845	COG0012	GTP binding
DKE43_14850	COG4481	Protein conserved in bacteria
DKE43_14865	COG3949	Membrane
DKE43_14875	COG1475	DNA binding
DKE43_14880	COG1192	Involved in chromosome partitioning
DKE43_14890	COG1475	DNA binding
DKE43_14895	COG0357	Ribosomal RNA small subunit methyltransferase G
DKE43_14900	COG0445	tRNA wobble uridine modification
DKE43_14905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DKE43_14910	COG1847	R3H domain protein
DKE43_14915	COG0706	membrane insertase activity
DKE43_14920	COG0594	ribonuclease P activity
DKE43_14925	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DKE43_14930	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DKE43_14935	COG0592	DNA-directed DNA polymerase activity
DKE43_14940	COG2501	S4 domain
DKE43_14945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DKE43_14955	COG0187	DNA topoisomerase II activity
DKE43_14960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DKE43_14995	COG0516	GMP reductase activity
DKE43_14995	COG0517	IMP dehydrogenase activity
DKE43_15000	COG1686	Belongs to the peptidase S11 family
DKE43_15005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKE43_15010	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DKE43_15015	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DKE43_15020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DKE43_15025	COG0840	transmembrane signaling receptor activity
DKE43_15035	COG1428	Deoxynucleoside kinase
DKE43_15040	COG1428	Deoxynucleoside kinase
DKE43_15045	COG1388	LysM domain
DKE43_15045	COG3858	chitin binding
DKE43_15050	COG1335	isochorismatase
DKE43_15055	COG0590	tRNA wobble adenosine to inosine editing
DKE43_15065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DKE43_15070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DKE43_15075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DKE43_15120	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
DKE43_15125	COG3853	Toxic anion resistance protein (TelA)
DKE43_15130	COG1982	Orn Lys Arg decarboxylase major
DKE43_15135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DKE43_15140	COG3870	Protein conserved in bacteria
DKE43_15145	COG1728	Protein conserved in bacteria
DKE43_15150	COG0470	DNA polymerase III
DKE43_15155	COG1774	PSP1 C-terminal conserved region
DKE43_15160	COG4467	Involved in initiation control of chromosome replication
DKE43_15165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DKE43_15170	COG2827	Endonuclease containing a URI domain
DKE43_15175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DKE43_15180	COG2002	toxin-antitoxin pair type II binding
DKE43_15185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE43_15185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKE43_15190	COG0084	hydrolase, TatD family'
DKE43_15195	COG3583	domain protein
DKE43_15195	COG3584	3D domain protein
DKE43_15200	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DKE43_15205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKE43_15215	COG4466	Protein conserved in bacteria
DKE43_15225	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DKE43_15230	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DKE43_15235	COG0251	oxidation-reduction process
DKE43_15240	COG2088	sporulation resulting in formation of a cellular spore
DKE43_15250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKE43_15255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DKE43_15260	COG0193	aminoacyl-tRNA hydrolase activity
DKE43_15270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DKE43_15275	COG2002	toxin-antitoxin pair type II binding
DKE43_15280	COG2244	polysaccharide biosynthetic process
DKE43_15285	COG3956	TIGRFAM MazG family protein
DKE43_15290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DKE43_15305	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DKE43_15310	COG1098	S1 RNA binding domain
DKE43_15325	COG2208	phosphoserine phosphatase activity
DKE43_15330	COG2304	oxidoreductase activity
DKE43_15335	COG0515	serine threonine protein kinase
DKE43_15340	COG0037	tRNA processing
DKE43_15350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKE43_15355	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DKE43_15360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKE43_15365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKE43_15370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DKE43_15375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DKE43_15380	COG0512	Glutamine amidotransferase of anthranilate synthase
DKE43_15385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DKE43_15390	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DKE43_15395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DKE43_15400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DKE43_15405	COG1396	sequence-specific DNA binding
DKE43_15410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKE43_15415	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DKE43_15495	COG4463	regulation of RNA biosynthetic process
DKE43_15500	COG3880	PFAM UvrB UvrC protein
DKE43_15505	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DKE43_15510	COG0542	response to heat
DKE43_15515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DKE43_15520	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
DKE43_15525	COG4956	integral membrane protein (PIN domain superfamily)
DKE43_15530	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DKE43_15535	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DKE43_15540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKE43_15545	COG1045	serine acetyltransferase
DKE43_15550	COG0215	cysteine-tRNA ligase activity
DKE43_15555	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DKE43_15560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKE43_15565	COG3688	RNA-binding protein containing a PIN domain
DKE43_15570	COG1595	DNA-templated transcription, initiation
DKE43_15575	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DKE43_15580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DKE43_15585	COG0250	Participates in transcription elongation, termination and antitermination
DKE43_15590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DKE43_15595	COG0081	regulation of translation
DKE43_15600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DKE43_15605	COG0222	ribosome binding
DKE43_15610	COG2813	Specifically methylates the guanine in position
DKE43_15615	COG0085	RNA polymerase activity
DKE43_15620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DKE43_15625	COG1358	cellular component organization or biogenesis
DKE43_15630	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DKE43_15635	COG0049	tRNA binding
DKE43_15640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DKE43_15645	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKE43_15650	COG0596	Alpha beta hydrolase
DKE43_15655	COG0051	transcription antitermination factor activity, RNA binding
DKE43_15660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKE43_15665	COG0088	Forms part of the polypeptide exit tunnel
DKE43_15670	COG0089	rRNA binding
DKE43_15675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DKE43_15680	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DKE43_15685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DKE43_15690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DKE43_15695	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DKE43_15700	COG0255	Belongs to the universal ribosomal protein uL29 family
DKE43_15705	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DKE43_15710	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DKE43_15715	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DKE43_15720	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DKE43_15725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DKE43_15730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DKE43_15735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DKE43_15740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DKE43_15745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DKE43_15750	COG1841	ribosomal large subunit assembly
DKE43_15755	COG0200	Binds to the 23S rRNA
DKE43_15760	COG0201	protein transport
DKE43_15765	COG0563	adenylate kinase activity
DKE43_15770	COG0024	Methionine aminopeptidase
DKE43_15780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DKE43_15785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DKE43_15790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DKE43_15795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DKE43_15800	COG0202	RNA polymerase activity
DKE43_15805	COG0203	ribosomal protein L17
DKE43_15810	COG1122	ATPase activity
DKE43_15815	COG1122	ATPase activity
DKE43_15820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DKE43_15825	COG0101	tRNA pseudouridine synthase activity
DKE43_15830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DKE43_15835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DKE43_15840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE43_15870	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKE43_15875	COG0489	protein tyrosine kinase activity
DKE43_15885	COG2194	sulfuric ester hydrolase activity
DKE43_15890	COG0726	polysaccharide deacetylase
DKE43_15920	COG0659	secondary active sulfate transmembrane transporter activity
DKE43_15925	COG0385	Bile acid
DKE43_15930	COG3876	Protein conserved in bacteria
DKE43_15935	COG1472	Belongs to the glycosyl hydrolase 3 family
DKE43_15940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DKE43_15945	COG1263	PTS System
DKE43_15945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_15950	COG1737	Transcriptional regulator
DKE43_15955	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DKE43_15990	COG1595	DNA-templated transcription, initiation
DKE43_15995	COG5662	AntiSigma factor
DKE43_16000	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DKE43_16005	COG4856	YbbR-like protein
DKE43_16010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DKE43_16015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKE43_16035	COG0084	hydrolase, TatD family'
DKE43_16050	COG1131	(ABC) transporter
DKE43_16065	COG1131	(ABC) transporter
DKE43_16075	COG1413	lyase activity
DKE43_16085	COG2311	Membrane
DKE43_16110	COG1309	transcriptional regulator
DKE43_16125	COG1113	amino acid transport
DKE43_16130	COG0584	glycerophosphoryl diester phosphodiesterase
DKE43_16135	COG2271	Major facilitator Superfamily
DKE43_16140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKE43_16145	COG1331	Highly conserved protein containing a thioredoxin domain
DKE43_16155	COG1131	(ABC) transporter
DKE43_16185	COG1937	Protein conserved in bacteria
DKE43_16190	COG2210	Belongs to the sulfur carrier protein TusA family
DKE43_16195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKE43_16200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKE43_16200	COG0425	Belongs to the sulfur carrier protein TusA family
DKE43_16205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKE43_16205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKE43_16210	COG0425	Belongs to the sulfur carrier protein TusA family
DKE43_16215	COG0730	response to heat
DKE43_16220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DKE43_16225	COG2814	Major facilitator Superfamily
DKE43_16230	COG1846	Transcriptional regulator
DKE43_16240	COG1683	Conserved Protein
DKE43_16250	COG0656	L-ascorbic acid biosynthetic process
DKE43_16255	COG0371	Dehydrogenase
DKE43_16265	COG0531	amino acid
DKE43_16275	COG3711	transcriptional antiterminator
DKE43_16280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_16280	COG2190	(PTS) system
DKE43_16280	COG1263	PTS System
DKE43_16285	COG2723	6-phospho-beta-galactosidase activity
DKE43_16300	COG3711	transcriptional antiterminator
DKE43_16300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_16305	COG1940	carbohydrate kinase activity
DKE43_16310	COG0383	alpha-mannosidase activity
DKE43_16315	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_16320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKE43_16325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_16325	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_16330	COG1404	Belongs to the peptidase S8 family
DKE43_16345	COG0833	amino acid
DKE43_16350	COG2040	homocysteine
DKE43_16355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DKE43_16360	COG1695	Transcriptional regulator
DKE43_16370	COG2814	Major facilitator Superfamily
DKE43_16390	COG1404	Belongs to the peptidase S8 family
DKE43_16400	COG1309	transcriptional regulator
DKE43_16405	COG1917	Cupin 2, conserved barrel domain protein
DKE43_16410	COG1063	alcohol dehydrogenase
DKE43_16415	COG1846	Transcriptional regulator
DKE43_16420	COG0318	PFAM AMP-dependent synthetase and ligase
DKE43_16425	COG0531	amino acid
DKE43_16440	COG0596	Alpha beta hydrolase
DKE43_16445	COG1115	amino acid carrier protein
DKE43_16450	COG2066	Belongs to the glutaminase family
DKE43_16455	COG4191	Histidine kinase
DKE43_16460	COG0784	Response regulator, receiver
DKE43_16465	COG1405	negative regulation of cell septum assembly
DKE43_16465	COG3012	SEC-C Motif Domain Protein
DKE43_16475	COG0667	Aldo Keto reductase
DKE43_16480	COG3290	protein histidine kinase activity
DKE43_16485	COG3279	Response regulator of the LytR AlgR family
DKE43_16490	COG4555	ABC transporter
DKE43_16495	COG1668	transmembrane transport
DKE43_16515	COG3773	Cell wall hydrolase
DKE43_16520	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_16530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKE43_16535	COG2310	stress, protein
DKE43_16540	COG2310	stress, protein
DKE43_16545	COG2310	stress, protein
DKE43_16550	COG0861	Integral membrane protein TerC family
DKE43_16580	COG3853	Toxic anion resistance protein (TelA)
DKE43_16585	COG4175	Glycine betaine
DKE43_16585	COG0517	IMP dehydrogenase activity
DKE43_16590	COG4176	ABC-type proline glycine betaine transport system permease component
DKE43_16595	COG2113	Glycine betaine
DKE43_16610	COG1473	amidohydrolase
DKE43_16615	COG1288	antiporter activity
DKE43_16620	COG0039	L-malate dehydrogenase activity
DKE43_16625	COG1620	l-lactate permease
DKE43_16630	COG1609	Transcriptional regulator
DKE43_16635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DKE43_16640	COG0561	phosphatase activity
DKE43_16645	COG0673	inositol 2-dehydrogenase activity
DKE43_16650	COG0738	Major facilitator superfamily
DKE43_16655	COG1280	lysine exporter protein (LysE YggA)
DKE43_16665	COG3403	YqcI/YcgG family
DKE43_16670	COG1113	amino acid transport
DKE43_16675	COG3665	Urea carboxylase-associated protein
DKE43_16680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DKE43_16685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKE43_16695	COG0477	Major facilitator Superfamily
DKE43_16700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DKE43_16705	COG2226	methyltransferase
DKE43_16710	COG0583	DNA-binding transcription factor activity
DKE43_16715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKE43_16720	COG3458	cephalosporin-C deacetylase activity
DKE43_16730	COG3541	Predicted nucleotidyltransferase
DKE43_16735	COG0506	proline dehydrogenase activity
DKE43_16740	COG1012	belongs to the aldehyde dehydrogenase family
DKE43_16745	COG2508	Transcriptional regulator
DKE43_16750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DKE43_16755	COG0765	amino acid transport
DKE43_16760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_16770	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DKE43_16775	COG1522	sequence-specific DNA binding
DKE43_16780	COG2746	aminoglycoside 3-N-acetyltransferase activity
DKE43_16790	COG3290	protein histidine kinase activity
DKE43_16790	COG0840	transmembrane signaling receptor activity
DKE43_16795	COG3209	COG3209 Rhs family protein
DKE43_16820	COG3842	ATPase activity
DKE43_16825	COG1176	ABC-type spermidine putrescine transport system, permease component I
DKE43_16835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKE43_16840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKE43_16845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DKE43_16860	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DKE43_16875	COG4555	ABC transporter
DKE43_16890	COG0697	spore germination
DKE43_16895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKE43_16905	COG2364	Membrane
DKE43_16910	COG1126	abc transporter atp-binding protein
DKE43_16915	COG0765	amino acid transport
DKE43_16920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_16925	COG0833	amino acid
DKE43_16930	COG3104	oligopeptide transport
DKE43_16935	COG5434	Belongs to the glycosyl hydrolase 28 family
DKE43_16950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKE43_16955	COG0765	amino acid transport
DKE43_16960	COG1126	abc transporter atp-binding protein
DKE43_16970	COG2079	MmgE PrpD family protein
DKE43_16975	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_16980	COG0527	aspartate kinase activity
DKE43_16985	COG2814	Major facilitator Superfamily
DKE43_16990	COG1309	transcriptional regulator
DKE43_17000	COG0640	Transcriptional regulator
DKE43_17005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKE43_17010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DKE43_17015	COG0531	amino acid
DKE43_17020	COG1012	belongs to the aldehyde dehydrogenase family
DKE43_17025	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKE43_17030	COG4549	nuclear export factor GLE1
DKE43_17035	COG2372	response to copper ion
DKE43_17035	COG1276	copper resistance
DKE43_17040	COG2213	PTS system mannitol-specific
DKE43_17045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKE43_17050	COG0246	Mannitol dehydrogenase
DKE43_17055	COG0840	transmembrane signaling receptor activity
DKE43_17075	COG0346	lactoylglutathione lyase activity
DKE43_17085	COG0561	phosphatase activity
DKE43_17090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DKE43_17095	COG1914	H( )-stimulated, divalent metal cation uptake system
DKE43_17100	COG4336	lyase activity
DKE43_17105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DKE43_17110	COG1984	allophanate hydrolase subunit 2
DKE43_17115	COG1414	Transcriptional regulator
DKE43_17120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DKE43_17125	COG2755	lipolytic protein G-D-S-L family
DKE43_17135	COG3711	transcriptional antiterminator
DKE43_17140	COG2226	methyltransferase
DKE43_17145	COG1028	Short-chain dehydrogenase reductase Sdr
DKE43_17150	COG3871	stress protein (general stress protein 26)
DKE43_17170	COG2814	Major facilitator Superfamily
DKE43_17175	COG1802	Transcriptional regulator
DKE43_17180	COG1917	Cupin 2, conserved barrel domain protein
DKE43_17180	COG2207	Transcriptional regulator
DKE43_17185	COG0697	spore germination
DKE43_17190	COG0473	3-isopropylmalate dehydrogenase activity
DKE43_17195	COG0551	DNA topoisomerase type I activity
DKE43_17195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DKE43_17200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DKE43_17205	COG3706	GGDEF domain
DKE43_17210	COG5298	Protein conserved in bacteria
DKE43_17215	COG1215	transferase activity, transferring glycosyl groups
DKE43_17225	COG0531	amino acid
DKE43_17230	COG0028	Belongs to the TPP enzyme family
DKE43_17235	COG5444	nuclease activity
DKE43_17260	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKE43_17265	COG1914	H( )-stimulated, divalent metal cation uptake system
DKE43_17270	COG2261	transglycosylase associated protein
DKE43_17275	COG2217	Heavy metal translocating P-type atpase
DKE43_17280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DKE43_17285	COG3290	protein histidine kinase activity
DKE43_17290	COG4565	transcriptional regulatory protein
DKE43_17295	COG1301	dicarboxylic acid transport
DKE43_17300	COG0628	permease
DKE43_17305	COG1301	dicarboxylic acid transport
DKE43_17310	COG1131	(ABC) transporter
DKE43_17315	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DKE43_17330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKE43_17335	COG1181	Belongs to the D-alanine--D-alanine ligase family
DKE43_17340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKE43_17355	COG0513	Belongs to the DEAD box helicase family
DKE43_17360	COG3402	PFAM membrane-flanked domain
DKE43_17365	COG3428	Bacterial PH domain
DKE43_17370	COG0705	Rhomboid family
DKE43_17375	COG0736	holo-[acyl-carrier-protein] synthase activity
DKE43_17380	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DKE43_17385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKE43_17390	COG0864	Transcriptional regulator
DKE43_17395	COG2337	Toxic component of a toxin-antitoxin (TA) module
DKE43_17400	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_17405	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_17410	COG2172	sigma factor antagonist activity
DKE43_17415	COG2208	phosphoserine phosphatase activity
DKE43_17420	COG1366	Belongs to the anti-sigma-factor antagonist family
DKE43_17425	COG2172	sigma factor antagonist activity
DKE43_17430	COG1191	sigma factor activity
DKE43_17435	COG2208	phosphoserine phosphatase activity
DKE43_17440	COG2183	response to ionizing radiation
DKE43_17450	COG3091	SprT-like family
DKE43_17455	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DKE43_17460	COG0022	dehydrogenase e1 component
DKE43_17465	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKE43_17470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKE43_17475	COG3284	Transcriptional regulator
DKE43_17515	COG0582	viral genome integration into host DNA
DKE43_17520	COG2856	Zn peptidase
DKE43_17525	COG1396	sequence-specific DNA binding
DKE43_17550	COG1674	ftsk spoiiie
DKE43_17555	COG2946	Replication initiation factor
DKE43_17645	COG0433	COG0433 Predicted ATPase
DKE43_17650	COG5644	endopeptidase inhibitor activity
DKE43_17655	COG0791	NLP P60 protein
DKE43_17655	COG0741	lytic transglycosylase activity
DKE43_17665	COG0457	Tetratricopeptide repeat
DKE43_17685	COG1278	Cold shock
DKE43_17690	COG1329	Transcriptional regulator
DKE43_17695	COG1064	alcohol dehydrogenase
DKE43_17700	COG0789	Transcriptional regulator
DKE43_17715	COG0477	Major facilitator Superfamily
DKE43_17750	COG0252	asparaginase activity
DKE43_17770	COG2814	Major facilitator Superfamily
DKE43_17805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DKE43_17810	COG1846	Transcriptional regulator
DKE43_17815	COG0778	Nitroreductase
DKE43_17830	COG1396	sequence-specific DNA binding
DKE43_17840	COG0456	acetyltransferase
DKE43_17845	COG0583	DNA-binding transcription factor activity
DKE43_17850	COG0667	Aldo Keto reductase
DKE43_17870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DKE43_17875	COG0697	spore germination
DKE43_17885	COG1301	dicarboxylic acid transport
DKE43_17925	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DKE43_17930	COG0802	atpase or kinase
DKE43_17935	COG1214	PFAM Peptidase M22, glycoprotease
DKE43_17940	COG0456	acetyltransferase
DKE43_17945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DKE43_17950	COG0488	(ABC) transporter
DKE43_17955	COG0315	cyclic pyranopterin monophosphate synthase activity
DKE43_17960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DKE43_17965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DKE43_17970	COG0805	protein transport
DKE43_17975	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DKE43_17985	COG1266	CAAX protease self-immunity
DKE43_17990	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DKE43_17995	COG0459	protein refolding
DKE43_18010	COG1846	Transcriptional regulator
DKE43_18015	COG0456	acetyltransferase
DKE43_18020	COG2808	Putative FMN-binding domain
DKE43_18040	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DKE43_18045	COG0823	Involved in the tonB-independent uptake of proteins
DKE43_18060	COG2132	Multicopper oxidase
DKE43_18065	COG1113	amino acid transport
DKE43_18070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DKE43_18075	COG0714	Associated with various cellular activities
DKE43_18080	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DKE43_18085	COG1305	Transglutaminase-like
DKE43_18090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKE43_18090	COG0519	Catalyzes the synthesis of GMP from XMP
DKE43_18095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DKE43_18100	COG2207	Transcriptional regulator
DKE43_18100	COG1917	Cupin 2, conserved barrel domain protein
DKE43_18105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKE43_18110	COG2207	Transcriptional regulator
DKE43_18135	COG2814	Major facilitator Superfamily
DKE43_18140	COG0583	DNA-binding transcription factor activity
DKE43_18145	COG2252	PERMEase
DKE43_18155	COG3064	Membrane
DKE43_18160	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
DKE43_18170	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DKE43_18175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DKE43_18180	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DKE43_18185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DKE43_18190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DKE43_18195	COG0047	phosphoribosylformylglycinamidine synthase activity
DKE43_18200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DKE43_18205	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DKE43_18210	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DKE43_18215	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DKE43_18220	COG0138	bifunctional purine biosynthesis protein purh
DKE43_18225	COG0151	Belongs to the GarS family
DKE43_18245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DKE43_18250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DKE43_18255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DKE43_18260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DKE43_18270	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DKE43_18275	COG4496	protein, YerC YecD
DKE43_18280	COG0069	glutamate synthase activity
DKE43_18295	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
DKE43_18300	COG0210	DNA helicase
DKE43_18305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DKE43_18310	COG4851	CamS sex pheromone cAM373 precursor
DKE43_18325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DKE43_18340	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKE43_18355	COG1960	acyl-CoA dehydrogenase activity
DKE43_18385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DKE43_18390	COG1785	Belongs to the alkaline phosphatase family
DKE43_18395	COG1285	pathogenesis
DKE43_18400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKE43_18405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE43_18410	COG0154	amidase activity
DKE43_18415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKE43_18420	COG1309	transcriptional regulator
DKE43_18425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKE43_18435	COG1597	lipid kinase activity
DKE43_18440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKE43_18455	COG0457	Tetratricopeptide repeat
DKE43_18460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKE43_18470	COG1737	Transcriptional regulator
DKE43_18475	COG1263	PTS System
DKE43_18475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKE43_18480	COG1486	melibiose metabolic process
DKE43_18490	COG1959	2 iron, 2 sulfur cluster binding
DKE43_18495	COG0492	ferredoxin-NADP+ reductase activity
DKE43_18510	COG1486	melibiose metabolic process
DKE43_18520	COG2211	Major facilitator Superfamily
DKE43_18550	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DKE43_18555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKE43_18560	COG1442	glycosyl transferase family 8
DKE43_18565	COG1216	Glycosyl transferase, family 2
DKE43_18570	COG1442	glycosyl transferase family 8
DKE43_18575	COG2223	nitrite transmembrane transporter activity
DKE43_18585	COG0471	metal ion transport
DKE43_18590	COG0531	amino acid
DKE43_18595	COG0463	Glycosyl transferase, family 2
DKE43_18595	COG0457	Tetratricopeptide repeat
DKE43_18600	COG0488	(ABC) transporter
DKE43_18605	COG1469	GTP cyclohydrolase I activity
DKE43_18610	COG0789	Transcriptional regulator
DKE43_18615	COG2814	Major facilitator Superfamily
DKE43_18620	COG0488	(ABC) transporter
DKE43_18625	COG0513	Belongs to the DEAD box helicase family
DKE43_18630	COG2130	NADP-dependent
DKE43_18650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKE43_18650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKE43_18655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DKE43_18665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DKE43_18665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate