locus-tag	class	description
M0696_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
M0696_00010	COG0592	DNA-directed DNA polymerase activity
M0696_00015	COG2501	S4 domain
M0696_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
M0696_00030	COG0187	DNA topoisomerase II activity
M0696_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M0696_00070	COG0516	GMP reductase activity
M0696_00070	COG0517	IMP dehydrogenase activity
M0696_00075	COG1686	Belongs to the peptidase S11 family
M0696_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
M0696_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
M0696_00100	COG1428	Deoxynucleoside kinase
M0696_00105	COG1428	Deoxynucleoside kinase
M0696_00110	COG1388	LysM domain
M0696_00110	COG3858	chitin binding
M0696_00115	COG1335	isochorismatase
M0696_00120	COG0590	tRNA wobble adenosine to inosine editing
M0696_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M0696_00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
M0696_00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M0696_00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
M0696_00190	COG3853	Toxic anion resistance protein (TelA)
M0696_00195	COG1982	Orn Lys Arg decarboxylase major
M0696_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M0696_00205	COG3870	Protein conserved in bacteria
M0696_00210	COG1728	Protein conserved in bacteria
M0696_00215	COG0470	DNA polymerase III
M0696_00220	COG1774	PSP1 C-terminal conserved region
M0696_00225	COG4467	Involved in initiation control of chromosome replication
M0696_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M0696_00235	COG2827	Endonuclease containing a URI domain
M0696_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M0696_00245	COG2002	toxin-antitoxin pair type II binding
M0696_00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_00255	COG0084	hydrolase, TatD family'
M0696_00260	COG3583	domain protein
M0696_00260	COG3584	3D domain protein
M0696_00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M0696_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M0696_00280	COG4466	Protein conserved in bacteria
M0696_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
M0696_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M0696_00300	COG0251	oxidation-reduction process
M0696_00305	COG2088	sporulation resulting in formation of a cellular spore
M0696_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
M0696_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M0696_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
M0696_00325	COG0193	aminoacyl-tRNA hydrolase activity
M0696_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M0696_00340	COG2002	toxin-antitoxin pair type II binding
M0696_00345	COG2244	polysaccharide biosynthetic process
M0696_00350	COG3956	TIGRFAM MazG family protein
M0696_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M0696_00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M0696_00375	COG1098	S1 RNA binding domain
M0696_00390	COG2208	phosphoserine phosphatase activity
M0696_00395	COG2304	oxidoreductase activity
M0696_00400	COG0515	serine threonine protein kinase
M0696_00405	COG0037	tRNA processing
M0696_00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M0696_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M0696_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
M0696_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M0696_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M0696_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M0696_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M0696_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
M0696_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M0696_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M0696_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M0696_00470	COG1396	sequence-specific DNA binding
M0696_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M0696_00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
M0696_00560	COG4463	regulation of RNA biosynthetic process
M0696_00565	COG3880	PFAM UvrB UvrC protein
M0696_00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
M0696_00575	COG0542	response to heat
M0696_00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M0696_00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
M0696_00590	COG4956	integral membrane protein (PIN domain superfamily)
M0696_00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M0696_00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
M0696_00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M0696_00610	COG1045	serine acetyltransferase
M0696_00615	COG0215	cysteine-tRNA ligase activity
M0696_00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M0696_00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M0696_00630	COG3688	RNA-binding protein containing a PIN domain
M0696_00635	COG1595	DNA-templated transcription, initiation
M0696_00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M0696_00650	COG0250	Participates in transcription elongation, termination and antitermination
M0696_00660	COG0081	regulation of translation
M0696_00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
M0696_00675	COG2813	Specifically methylates the guanine in position
M0696_00680	COG0085	RNA polymerase activity
M0696_00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M0696_00690	COG1358	cellular component organization or biogenesis
M0696_00700	COG0049	tRNA binding
M0696_00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
M0696_00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
M0696_00715	COG0596	Alpha beta hydrolase
M0696_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
M0696_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
M0696_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M0696_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M0696_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M0696_00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
M0696_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
M0696_00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
M0696_00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
M0696_00820	COG0200	Binds to the 23S rRNA
M0696_00825	COG0201	protein transport
M0696_00830	COG0563	adenylate kinase activity
M0696_00835	COG0024	Methionine aminopeptidase
M0696_00845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M0696_00855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
M0696_00860	COG0202	RNA polymerase activity
M0696_00865	COG0203	ribosomal protein L17
M0696_00870	COG1122	ATPase activity
M0696_00875	COG1122	ATPase activity
M0696_00880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M0696_00885	COG0101	tRNA pseudouridine synthase activity
M0696_00890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M0696_00900	COG2226	methyltransferase
M0696_00910	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_00915	COG0489	protein tyrosine kinase activity
M0696_00925	COG2194	sulfuric ester hydrolase activity
M0696_00930	COG0726	polysaccharide deacetylase
M0696_01010	COG0738	Major facilitator superfamily
M0696_01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M0696_01020	COG0483	inositol monophosphate 1-phosphatase activity
M0696_01025	COG1063	alcohol dehydrogenase
M0696_01030	COG0659	secondary active sulfate transmembrane transporter activity
M0696_01035	COG0385	Bile acid
M0696_01040	COG2819	hydrolase of the alpha beta superfamily
M0696_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_01060	COG2207	Transcriptional regulator
M0696_01065	COG3876	Protein conserved in bacteria
M0696_01070	COG1472	Belongs to the glycosyl hydrolase 3 family
M0696_01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_01080	COG1263	PTS System
M0696_01085	COG1737	Transcriptional regulator
M0696_01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
M0696_01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_01100	COG1683	Conserved Protein
M0696_01130	COG1595	DNA-templated transcription, initiation
M0696_01135	COG5662	AntiSigma factor
M0696_01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M0696_01145	COG4856	YbbR-like protein
M0696_01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M0696_01165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M0696_01170	COG3002	Belongs to the UPF0753 family
M0696_01175	COG0288	reversible hydration of carbon dioxide
M0696_01185	COG5609	conserved protein (DUF2294)
M0696_01190	COG0640	Transcriptional regulator
M0696_01195	COG2814	Major facilitator Superfamily
M0696_01210	COG0596	Alpha beta hydrolase
M0696_01215	COG0745	RESPONSE REGULATOR receiver
M0696_01220	COG0642	Histidine kinase
M0696_01230	COG0515	serine threonine protein kinase
M0696_01245	COG1113	amino acid transport
M0696_01260	COG2602	Beta-lactamase
M0696_01265	COG2124	cytochrome p450
M0696_01275	COG1283	sodium-dependent phosphate transmembrane transporter activity
M0696_01280	COG0584	glycerophosphoryl diester phosphodiesterase
M0696_01285	COG2271	Major facilitator Superfamily
M0696_01295	COG1846	Transcriptional regulator
M0696_01295	COG0456	acetyltransferase
M0696_01300	COG2271	Major facilitator Superfamily
M0696_01310	COG3409	Peptidoglycan-binding domain 1 protein
M0696_01315	COG0697	spore germination
M0696_01320	COG2207	Transcriptional regulator
M0696_01320	COG1917	Cupin 2, conserved barrel domain protein
M0696_01325	COG1397	ADP-ribosylglycohydrolase
M0696_01335	COG5444	nuclease activity
M0696_01340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
M0696_01345	COG3591	Belongs to the peptidase S1B family
M0696_01355	COG0596	Alpha beta hydrolase
M0696_01360	COG1183	phosphatidylcholine synthase activity
M0696_01365	COG0586	Pfam SNARE associated Golgi protein
M0696_01370	COG0688	phosphatidylethanolamine metabolic process
M0696_01380	COG2312	Erythromycin esterase
M0696_01385	COG1054	Belongs to the UPF0176 family
M0696_01390	COG1301	dicarboxylic acid transport
M0696_01395	COG2190	(PTS) system
M0696_01395	COG1263	PTS System
M0696_01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_01400	COG0363	glucosamine-6-phosphate deaminase activity
M0696_01405	COG2188	Transcriptional regulator
M0696_01415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_01420	COG0833	amino acid
M0696_01425	COG2040	homocysteine
M0696_01430	COG1115	amino acid carrier protein
M0696_01435	COG2066	Belongs to the glutaminase family
M0696_01440	COG4191	Histidine kinase
M0696_01445	COG0784	Response regulator, receiver
M0696_01450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M0696_01455	COG1012	belongs to the aldehyde dehydrogenase family
M0696_01460	COG2271	Major facilitator Superfamily
M0696_01465	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_01470	COG2186	Transcriptional regulator
M0696_01475	COG2721	sulfolactate sulfo-lyase activity
M0696_01480	COG3173	Aminoglycoside phosphotransferase
M0696_01490	COG0697	spore germination
M0696_01495	COG0745	RESPONSE REGULATOR receiver
M0696_01500	COG2205	protein histidine kinase activity
M0696_01505	COG1131	(ABC) transporter
M0696_01530	COG3773	Cell wall hydrolase
M0696_01545	COG3540	Alkaline phosphatase
M0696_01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M0696_01555	COG0805	protein transport
M0696_01560	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
M0696_01565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M0696_01570	COG0477	Major facilitator Superfamily
M0696_01575	COG1309	transcriptional regulator
M0696_01580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
M0696_01585	COG1714	RDD family
M0696_01590	COG3012	SEC-C Motif Domain Protein
M0696_01590	COG1405	negative regulation of cell septum assembly
M0696_01600	COG0667	Aldo Keto reductase
M0696_01615	COG1595	DNA-templated transcription, initiation
M0696_01620	COG1595	DNA-templated transcription, initiation
M0696_01625	COG1876	peptidase activity
M0696_01630	COG0457	Tetratricopeptide repeat
M0696_01635	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_01640	COG0366	Alpha amylase catalytic
M0696_01645	COG0803	Belongs to the bacterial solute-binding protein 9 family
M0696_01650	COG1121	(ABC) transporter
M0696_01655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M0696_01660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_01665	COG2310	stress, protein
M0696_01670	COG2310	stress, protein
M0696_01675	COG2310	stress, protein
M0696_01680	COG0861	Integral membrane protein TerC family
M0696_01695	COG1358	cellular component organization or biogenesis
M0696_01710	COG3853	Toxic anion resistance protein (TelA)
M0696_01715	COG0477	Major facilitator Superfamily
M0696_01720	COG2814	Major facilitator Superfamily
M0696_01725	COG0640	Transcriptional regulator
M0696_01730	COG0517	IMP dehydrogenase activity
M0696_01730	COG4175	Glycine betaine
M0696_01735	COG4176	ABC-type proline glycine betaine transport system permease component
M0696_01740	COG2113	Glycine betaine
M0696_01745	COG2323	membrane
M0696_01750	COG0038	chloride channel
M0696_01765	COG0366	Alpha amylase catalytic
M0696_01770	COG0039	L-malate dehydrogenase activity
M0696_01775	COG1620	l-lactate permease
M0696_01780	COG2814	Major facilitator Superfamily
M0696_01785	COG1846	Transcriptional regulator
M0696_01790	COG1280	lysine exporter protein (LysE YggA)
M0696_01795	COG3403	YqcI/YcgG family
M0696_01800	COG1113	amino acid transport
M0696_01805	COG3665	Urea carboxylase-associated protein
M0696_01810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M0696_01815	COG1660	Displays ATPase and GTPase activities
M0696_01820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
M0696_01825	COG2226	methyltransferase
M0696_01830	COG0583	DNA-binding transcription factor activity
M0696_01835	COG3458	cephalosporin-C deacetylase activity
M0696_01840	COG3541	Predicted nucleotidyltransferase
M0696_01845	COG0506	proline dehydrogenase activity
M0696_01850	COG1012	belongs to the aldehyde dehydrogenase family
M0696_01855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_01860	COG2508	Transcriptional regulator
M0696_01865	COG3689	TIGRFAM TIGR03943 family protein
M0696_01870	COG0701	Predicted permease
M0696_01875	COG2267	carboxylic ester hydrolase activity
M0696_01880	COG0492	ferredoxin-NADP+ reductase activity
M0696_01885	COG1587	Uroporphyrinogen-III synthase
M0696_01885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M0696_01890	COG2146	nitrite reductase [NAD(P)H] activity
M0696_01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M0696_01900	COG0243	molybdopterin cofactor binding
M0696_01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M0696_01910	COG2223	nitrite transmembrane transporter activity
M0696_01915	COG1469	GTP cyclohydrolase I activity
M0696_01920	COG1376	ErfK ybiS ycfS ynhG family protein
M0696_01930	COG0523	cobalamin synthesis protein
M0696_01935	COG0765	amino acid transport
M0696_01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_01950	COG1714	RDD family
M0696_01970	COG3842	ATPase activity
M0696_01975	COG2723	6-phospho-beta-galactosidase activity
M0696_01985	COG3209	COG3209 Rhs family protein
M0696_01990	COG0840	transmembrane signaling receptor activity
M0696_01990	COG3290	protein histidine kinase activity
M0696_01995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M0696_02000	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
M0696_02005	COG1733	regulation of RNA biosynthetic process
M0696_02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_02040	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M0696_02055	COG0697	spore germination
M0696_02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_02075	COG0701	Predicted permease
M0696_02080	COG2364	Membrane
M0696_02085	COG1126	abc transporter atp-binding protein
M0696_02090	COG0765	amino acid transport
M0696_02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_02100	COG0583	DNA-binding transcription factor activity
M0696_02105	COG0163	prenyltransferase activity
M0696_02110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
M0696_02125	COG0596	Alpha beta hydrolase
M0696_02130	COG3104	oligopeptide transport
M0696_02135	COG5434	Belongs to the glycosyl hydrolase 28 family
M0696_02145	COG0697	spore germination
M0696_02155	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M0696_02160	COG1136	(ABC) transporter
M0696_02165	COG0577	efflux transmembrane transporter activity
M0696_02170	COG0745	RESPONSE REGULATOR receiver
M0696_02175	COG5002	protein histidine kinase activity
M0696_02175	COG3850	Histidine kinase
M0696_02180	COG0457	Tetratricopeptide repeat
M0696_02195	COG0527	aspartate kinase activity
M0696_02200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_02205	COG4605	iron ion homeostasis
M0696_02210	COG4604	ABC transporter, ATP-binding protein
M0696_02215	COG4607	ABC-type enterochelin transport system periplasmic component
M0696_02220	COG2814	Major facilitator Superfamily
M0696_02225	COG1309	transcriptional regulator
M0696_02230	COG0778	Nitroreductase
M0696_02235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M0696_02240	COG0640	Transcriptional regulator
M0696_02245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_02250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M0696_02255	COG1012	belongs to the aldehyde dehydrogenase family
M0696_02260	COG4975	Glucose uptake
M0696_02265	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_02270	COG4549	nuclear export factor GLE1
M0696_02275	COG1276	copper resistance
M0696_02275	COG2372	response to copper ion
M0696_02280	COG1349	DNA-binding transcription factor activity
M0696_02290	COG2213	PTS system mannitol-specific
M0696_02295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_02300	COG0246	Mannitol dehydrogenase
M0696_02305	COG0473	3-isopropylmalate dehydrogenase activity
M0696_02310	COG0412	Dienelactone hydrolase
M0696_02315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M0696_02325	COG0561	phosphatase activity
M0696_02330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
M0696_02335	COG1914	H( )-stimulated, divalent metal cation uptake system
M0696_02340	COG4336	lyase activity
M0696_02345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M0696_02350	COG1984	allophanate hydrolase subunit 2
M0696_02355	COG1414	Transcriptional regulator
M0696_02360	COG2755	lipolytic protein G-D-S-L family
M0696_02370	COG2329	Antibiotic biosynthesis monooxygenase
M0696_02375	COG0768	penicillin binding
M0696_02380	COG4989	oxidoreductase activity
M0696_02385	COG3711	transcriptional antiterminator
M0696_02390	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_02395	COG2226	methyltransferase
M0696_02400	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_02405	COG1917	Cupin 2, conserved barrel domain protein
M0696_02410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_02415	COG3871	stress protein (general stress protein 26)
M0696_02425	COG2814	Major facilitator Superfamily
M0696_02430	COG1522	sequence-specific DNA binding
M0696_02435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M0696_02435	COG0551	DNA topoisomerase type I activity
M0696_02440	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M0696_02445	COG3706	GGDEF domain
M0696_02450	COG5298	Protein conserved in bacteria
M0696_02455	COG1215	transferase activity, transferring glycosyl groups
M0696_02465	COG0531	amino acid
M0696_02470	COG0494	nUDIX hydrolase
M0696_02475	COG0028	Belongs to the TPP enzyme family
M0696_02485	COG1914	H( )-stimulated, divalent metal cation uptake system
M0696_02490	COG2261	transglycosylase associated protein
M0696_02495	COG4876	unkown
M0696_02500	COG2217	Heavy metal translocating P-type atpase
M0696_02505	COG3729	General stress protein
M0696_02510	COG0662	Cupin 2, conserved barrel domain protein
M0696_02515	COG2329	Antibiotic biosynthesis monooxygenase
M0696_02520	COG3546	catalase activity
M0696_02525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M0696_02530	COG3290	protein histidine kinase activity
M0696_02535	COG4565	transcriptional regulatory protein
M0696_02540	COG1301	dicarboxylic acid transport
M0696_02545	COG0628	permease
M0696_02550	COG1301	dicarboxylic acid transport
M0696_02555	COG1131	(ABC) transporter
M0696_02560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M0696_02570	COG1960	acyl-CoA dehydrogenase activity
M0696_02585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M0696_02590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_02595	COG1181	Belongs to the D-alanine--D-alanine ligase family
M0696_02600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M0696_02605	COG0513	Belongs to the DEAD box helicase family
M0696_02610	COG3402	PFAM membrane-flanked domain
M0696_02615	COG3428	Bacterial PH domain
M0696_02620	COG0705	Rhomboid family
M0696_02625	COG0736	holo-[acyl-carrier-protein] synthase activity
M0696_02630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M0696_02635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M0696_02640	COG0864	Transcriptional regulator
M0696_02645	COG2337	Toxic component of a toxin-antitoxin (TA) module
M0696_02650	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_02655	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_02660	COG2172	sigma factor antagonist activity
M0696_02665	COG2208	phosphoserine phosphatase activity
M0696_02670	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_02675	COG2172	sigma factor antagonist activity
M0696_02680	COG1191	sigma factor activity
M0696_02685	COG2208	phosphoserine phosphatase activity
M0696_02690	COG2183	response to ionizing radiation
M0696_02700	COG3091	SprT-like family
M0696_02770	COG5444	nuclease activity
M0696_02785	COG2364	Membrane
M0696_02790	COG1846	Transcriptional regulator
M0696_02795	COG0456	acetyltransferase
M0696_02800	COG2808	Putative FMN-binding domain
M0696_02805	COG3239	Fatty acid desaturase
M0696_02810	COG1278	Cold shock
M0696_02815	COG1278	Cold shock
M0696_02825	COG1329	Transcriptional regulator
M0696_02830	COG2207	Transcriptional regulator
M0696_02830	COG3708	Transcriptional regulator
M0696_02835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_02840	COG0477	Major facilitator Superfamily
M0696_02845	COG1132	(ABC) transporter
M0696_02855	COG0640	Transcriptional regulator
M0696_02860	COG0346	lactoylglutathione lyase activity
M0696_02870	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
M0696_02885	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M0696_02890	COG1522	sequence-specific DNA binding
M0696_02895	COG0697	spore germination
M0696_02900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_02905	COG2030	dehydratase
M0696_02910	COG3545	Serine hydrolase
M0696_02915	COG1733	regulation of RNA biosynthetic process
M0696_02920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_02930	COG0640	Transcriptional regulator
M0696_02935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M0696_02940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M0696_02945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_02955	COG0697	spore germination
M0696_02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_02965	COG0076	glutamate decarboxylase activity
M0696_02970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M0696_02975	COG0640	Transcriptional regulator
M0696_02980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M0696_02995	COG4585	Histidine kinase
M0696_03000	COG2197	response regulator
M0696_03005	COG2409	Drug exporters of the RND superfamily
M0696_03015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_03020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M0696_03025	COG1687	branched-chain amino acid
M0696_03030	COG1114	Component of the transport system for branched-chain amino acids
M0696_03040	COG1811	Na channel or pump
M0696_03045	COG0789	Transcriptional regulator
M0696_03045	COG4978	Transcriptional regulator
M0696_03050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M0696_03055	COG0778	Nitroreductase
M0696_03060	COG0346	lactoylglutathione lyase activity
M0696_03065	COG2259	Doxx family
M0696_03070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_03090	COG2323	membrane
M0696_03095	COG2323	membrane
M0696_03100	COG0071	Belongs to the small heat shock protein (HSP20) family
M0696_03115	COG1309	transcriptional regulator
M0696_03125	COG0456	acetyltransferase
M0696_03135	COG2814	Major facilitator Superfamily
M0696_03145	COG0488	(ABC) transporter
M0696_03150	COG1113	amino acid transport
M0696_03155	COG2318	DinB family
M0696_03160	COG1846	Transcriptional regulator
M0696_03165	COG2409	Drug exporters of the RND superfamily
M0696_03165	COG1033	growth of symbiont in host cell
M0696_03175	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_03180	COG0778	Nitroreductase
M0696_03185	COG1846	Transcriptional regulator
M0696_03190	COG2814	Major facilitator Superfamily
M0696_03195	COG0730	response to heat
M0696_03200	COG1802	Transcriptional regulator
M0696_03205	COG1388	LysM domain
M0696_03205	COG3858	chitin binding
M0696_03220	COG1785	Belongs to the alkaline phosphatase family
M0696_03230	COG0454	-acetyltransferase
M0696_03235	COG1078	dGTPase activity
M0696_03240	COG1388	LysM domain
M0696_03245	COG2814	Major facilitator Superfamily
M0696_03250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_03255	COG1447	Phosphotransferase system cellobiose-specific component IIA
M0696_03260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_03265	COG2723	6-phospho-beta-galactosidase activity
M0696_03270	COG2188	Transcriptional regulator
M0696_03275	COG1940	carbohydrate kinase activity
M0696_03280	COG1482	cell wall glycoprotein biosynthetic process
M0696_03285	COG4124	Belongs to the glycosyl hydrolase 26 family
M0696_03330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M0696_03335	COG0802	atpase or kinase
M0696_03340	COG1214	PFAM Peptidase M22, glycoprotease
M0696_03345	COG0456	acetyltransferase
M0696_03350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
M0696_03355	COG0488	(ABC) transporter
M0696_03360	COG0315	cyclic pyranopterin monophosphate synthase activity
M0696_03365	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
M0696_03370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M0696_03375	COG0805	protein transport
M0696_03385	COG1266	CAAX protease self-immunity
M0696_03395	COG0459	protein refolding
M0696_03430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M0696_03450	COG1073	alpha beta
M0696_03455	COG0457	Tetratricopeptide repeat
M0696_03460	COG1063	alcohol dehydrogenase
M0696_03465	COG2211	Major facilitator Superfamily
M0696_03470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_03475	COG1842	Phage shock protein A
M0696_03480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M0696_03485	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M0696_03490	COG4260	virion core protein, lumpy skin disease virus
M0696_03500	COG2814	Major facilitator Superfamily
M0696_03505	COG1063	alcohol dehydrogenase
M0696_03510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M0696_03515	COG0823	Involved in the tonB-independent uptake of proteins
M0696_03530	COG2267	carboxylic ester hydrolase activity
M0696_03540	COG2132	Multicopper oxidase
M0696_03545	COG1113	amino acid transport
M0696_03550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M0696_03555	COG0714	Associated with various cellular activities
M0696_03560	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M0696_03565	COG1305	Transglutaminase-like
M0696_03570	COG0519	Catalyzes the synthesis of GMP from XMP
M0696_03570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M0696_03575	COG2252	PERMEase
M0696_03580	COG3064	Membrane
M0696_03590	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
M0696_03600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M0696_03605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M0696_03610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M0696_03615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
M0696_03620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M0696_03625	COG0047	phosphoribosylformylglycinamidine synthase activity
M0696_03630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M0696_03635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M0696_03640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
M0696_03645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M0696_03650	COG0138	bifunctional purine biosynthesis protein purh
M0696_03655	COG0151	Belongs to the GarS family
M0696_03660	COG1522	sequence-specific DNA binding
M0696_03665	COG0531	amino acid
M0696_03675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M0696_03680	COG1470	cell adhesion involved in biofilm formation
M0696_03685	COG4496	protein, YerC YecD
M0696_03690	COG0069	glutamate synthase activity
M0696_03695	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
M0696_03700	COG0210	DNA helicase
M0696_03705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M0696_03710	COG4851	CamS sex pheromone cAM373 precursor
M0696_03715	COG2814	Major facilitator Superfamily
M0696_03725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_03735	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M0696_03740	COG1250	3-hydroxyacyl-CoA dehydrogenase
M0696_03785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_03790	COG1785	Belongs to the alkaline phosphatase family
M0696_03795	COG1285	pathogenesis
M0696_03800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_03805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M0696_03810	COG0154	amidase activity
M0696_03815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M0696_03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M0696_03830	COG1597	lipid kinase activity
M0696_03835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M0696_03840	COG2197	response regulator
M0696_03850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_03855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M0696_03860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M0696_03870	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_03875	COG1131	(ABC) transporter
M0696_03915	COG5444	nuclease activity
M0696_03930	COG2323	membrane
M0696_03940	COG0457	Tetratricopeptide repeat
M0696_03950	COG0217	transcriptional regulatory protein
M0696_03960	COG1309	transcriptional regulator
M0696_03965	COG3631	Ketosteroid isomerase-related protein
M0696_03990	COG3546	catalase activity
M0696_03995	COG0454	-acetyltransferase
M0696_04005	COG5578	integral membrane protein
M0696_04010	COG2972	Histidine kinase
M0696_04015	COG4753	response regulator
M0696_04015	COG2207	Transcriptional regulator
M0696_04020	COG1653	transport
M0696_04025	COG1175	transmembrane transport
M0696_04030	COG0395	ABC-type sugar transport system, permease component
M0696_04035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
M0696_04040	COG2207	Transcriptional regulator
M0696_04045	COG2755	lipolytic protein G-D-S-L family
M0696_04055	COG5578	integral membrane protein
M0696_04060	COG3401	FG-GAP repeat protein
M0696_04065	COG3401	FG-GAP repeat protein
M0696_04070	COG2755	lipolytic protein G-D-S-L family
M0696_04075	COG1874	Beta-galactosidase
M0696_04085	COG1653	transport
M0696_04090	COG4209	transmembrane transport
M0696_04095	COG0395	ABC-type sugar transport system, permease component
M0696_04100	COG1486	melibiose metabolic process
M0696_04105	COG2323	membrane
M0696_04110	COG2329	Antibiotic biosynthesis monooxygenase
M0696_04115	COG0346	lactoylglutathione lyase activity
M0696_04130	COG5583	Uncharacterized small protein (DUF2292)
M0696_04135	COG0670	Belongs to the BI1 family
M0696_04145	COG1846	Transcriptional regulator
M0696_04150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M0696_04170	COG1368	sulfuric ester hydrolase activity
M0696_04175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M0696_04180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_04185	COG1442	glycosyl transferase family 8
M0696_04190	COG1216	Glycosyl transferase, family 2
M0696_04195	COG1442	glycosyl transferase family 8
M0696_04200	COG2223	nitrite transmembrane transporter activity
M0696_04205	COG1011	Hydrolase
M0696_04210	COG0531	amino acid
M0696_04215	COG1012	belongs to the aldehyde dehydrogenase family
M0696_04220	COG0840	transmembrane signaling receptor activity
M0696_04225	COG0488	(ABC) transporter
M0696_04235	COG0789	Transcriptional regulator
M0696_04240	COG2814	Major facilitator Superfamily
M0696_04245	COG0488	(ABC) transporter
M0696_04250	COG0513	Belongs to the DEAD box helicase family
M0696_04255	COG0456	acetyltransferase
M0696_04260	COG2130	NADP-dependent
M0696_04265	COG1120	ATPase activity
M0696_04270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_04280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M0696_04295	COG3866	Pectate lyase
M0696_04300	COG0471	metal ion transport
M0696_04305	COG3290	protein histidine kinase activity
M0696_04310	COG4565	transcriptional regulatory protein
M0696_04315	COG3181	Tripartite tricarboxylate transporter family receptor
M0696_04320	COG2851	Citrate transporter
M0696_04325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_04330	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M0696_04335	COG1254	Belongs to the acylphosphatase family
M0696_04340	COG2258	MOSC domain
M0696_04360	COG0024	Methionine aminopeptidase
M0696_04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_04365	COG1263	PTS System
M0696_04370	COG1368	sulfuric ester hydrolase activity
M0696_04385	COG1115	amino acid carrier protein
M0696_04390	COG0531	amino acid
M0696_04405	COG0697	spore germination
M0696_04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_04410	COG1263	PTS System
M0696_04415	COG0366	Alpha amylase catalytic
M0696_04420	COG2188	Transcriptional regulator
M0696_04425	COG0778	Nitroreductase
M0696_04430	COG0737	Belongs to the 5'-nucleotidase family
M0696_04435	COG0693	protein deglycase activity
M0696_04440	COG2814	Major facilitator Superfamily
M0696_04445	COG4840	Belongs to the UPF0435 family
M0696_04450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M0696_04455	COG4980	gas vesicle protein
M0696_04460	COG1295	ribonuclease BN
M0696_04465	COG0477	Major facilitator Superfamily
M0696_04470	COG0387	Pfam Sodium calcium exchanger
M0696_04480	COG0668	transmembrane transport
M0696_04485	COG0535	radical SAM domain protein
M0696_04495	COG0726	polysaccharide deacetylase
M0696_04500	COG2084	Dehydrogenase
M0696_04505	COG0598	Magnesium transport protein CorA
M0696_04510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M0696_04520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M0696_04535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M0696_04545	COG4637	Psort location Cytoplasmic, score
M0696_04555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M0696_04560	COG0022	dehydrogenase e1 component
M0696_04565	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_04570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M0696_04575	COG3284	Transcriptional regulator
M0696_04585	COG1742	UPF0060 membrane protein
M0696_04605	COG4842	Belongs to the WXG100 family
M0696_04610	COG1486	melibiose metabolic process
M0696_04615	COG1737	Transcriptional regulator
M0696_04620	COG1263	PTS System
M0696_04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_04625	COG1132	(ABC) transporter
M0696_04630	COG1132	(ABC) transporter
M0696_04635	COG2259	Doxx family
M0696_04640	COG2514	catechol 2,3-dioxygenase activity
M0696_04645	COG1917	Cupin 2, conserved barrel domain protein
M0696_04645	COG4977	sequence-specific DNA binding
M0696_04650	COG2814	Major facilitator Superfamily
M0696_04655	COG1082	Xylose isomerase domain protein TIM barrel
M0696_04660	COG0673	inositol 2-dehydrogenase activity
M0696_04670	COG2197	response regulator
M0696_04675	COG1131	(ABC) transporter
M0696_04680	COG0842	Transport permease protein
M0696_04680	COG1511	domain protein
M0696_04685	COG0842	Transport permease protein
M0696_04695	COG1695	Transcriptional regulator
M0696_04700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
M0696_04705	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
M0696_04710	COG2318	DinB family
M0696_04715	COG2814	Major facilitator Superfamily
M0696_04720	COG1846	Transcriptional regulator
M0696_04725	COG0392	lysyltransferase activity
M0696_04725	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M0696_04730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_04735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_04745	COG0384	phenazine biosynthesis protein PhzF
M0696_04750	COG0778	Nitroreductase
M0696_04765	COG1090	epimerase
M0696_04770	COG2137	regulation of response to DNA damage stimulus
M0696_04780	COG2814	Major facilitator Superfamily
M0696_04795	COG3103	Sh3 type 3 domain protein
M0696_04800	COG5658	integral membrane protein
M0696_04805	COG0596	Alpha beta hydrolase
M0696_04810	COG0463	Glycosyl transferase, family 2
M0696_04815	COG4485	Bacterial membrane protein, YfhO
M0696_04820	COG1988	membrane-bound metal-dependent
M0696_04825	COG1194	a g-specific adenine glycosylase
M0696_04835	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_04850	COG3557	Belongs to the UPF0374 family
M0696_04855	COG1132	(ABC) transporter
M0696_04860	COG4129	membrane
M0696_04865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
M0696_04870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M0696_04875	COG0735	belongs to the Fur family
M0696_04985	COG4326	sporulation control protein
M0696_04995	COG5577	PFAM Coat F domain
M0696_05000	COG3340	Belongs to the peptidase S51 family
M0696_05005	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
M0696_05015	COG0753	catalase activity
M0696_05020	COG1116	anion transmembrane transporter activity
M0696_05025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M0696_05030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M0696_05035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_05045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
M0696_05055	COG1476	TRANSCRIPTIONal
M0696_05065	COG3382	B3 4 domain protein
M0696_05070	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M0696_05080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M0696_05085	COG0789	Transcriptional regulator
M0696_05090	COG1664	Polymer-forming cytoskeletal
M0696_05095	COG1664	Polymer-forming cytoskeletal
M0696_05100	COG2766	serine protein kinase
M0696_05105	COG2718	Belongs to the UPF0229 family
M0696_05110	COG1846	Transcriptional regulator
M0696_05115	COG1566	PFAM secretion protein HlyD family protein
M0696_05120	COG2814	Major facilitator Superfamily
M0696_05125	COG0655	NAD(P)H dehydrogenase (quinone) activity
M0696_05140	COG1725	Transcriptional regulator
M0696_05145	COG1131	(ABC) transporter
M0696_05150	COG1131	(ABC) transporter
M0696_05155	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M0696_05160	COG1278	Cold shock
M0696_05165	COG1464	Belongs to the NlpA lipoprotein family
M0696_05170	COG3706	GGDEF domain
M0696_05175	COG1823	symporter activity
M0696_05195	COG5577	PFAM Coat F domain
M0696_05200	COG4085	toxin activity
M0696_05200	COG1525	nuclease
M0696_05200	COG0737	Belongs to the 5'-nucleotidase family
M0696_05205	COG3764	Sortase (surface protein transpeptidase)
M0696_05210	COG0564	pseudouridine synthase activity
M0696_05220	COG0517	IMP dehydrogenase activity
M0696_05225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M0696_05230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M0696_05230	COG3153	acetyltransferase
M0696_05240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M0696_05245	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M0696_05250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M0696_05255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M0696_05260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M0696_05265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M0696_05270	COG4585	Histidine kinase
M0696_05270	COG2203	Gaf domain
M0696_05275	COG2197	response regulator
M0696_05280	COG0431	NADPH-dependent FMN reductase
M0696_05295	COG0791	NLP P60 protein
M0696_05295	COG1388	LysM domain
M0696_05300	COG1959	2 iron, 2 sulfur cluster binding
M0696_05310	COG2719	SpoVR family
M0696_05315	COG1785	Belongs to the alkaline phosphatase family
M0696_05320	COG1388	LysM domain
M0696_05320	COG0791	NLP P60 protein
M0696_05325	COG0583	DNA-binding transcription factor activity
M0696_05330	COG0372	Belongs to the citrate synthase family
M0696_05335	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_05340	COG0531	amino acid
M0696_05345	COG0733	neurotransmitter:sodium symporter activity
M0696_05350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_05355	COG0456	acetyltransferase
M0696_05370	COG1595	DNA-templated transcription, initiation
M0696_05375	COG0667	Aldo Keto reductase
M0696_05380	COG0204	Acyl-transferase
M0696_05385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_05395	COG1253	flavin adenine dinucleotide binding
M0696_05400	COG0789	Transcriptional regulator
M0696_05405	COG0436	Aminotransferase
M0696_05410	COG1253	flavin adenine dinucleotide binding
M0696_05415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M0696_05420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M0696_05425	COG0584	glycerophosphoryl diester phosphodiesterase
M0696_05435	COG0668	transmembrane transport
M0696_05440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M0696_05445	COG0726	polysaccharide deacetylase
M0696_05450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_05455	COG1757	Na H antiporter
M0696_05460	COG0589	response to stress
M0696_05470	COG1132	(ABC) transporter
M0696_05475	COG1132	(ABC) transporter
M0696_05480	COG0702	epimerase
M0696_05500	COG0189	ligase activity
M0696_05505	COG0189	ligase activity
M0696_05510	COG4399	Belongs to the UPF0754 family
M0696_05515	COG3679	Belongs to the UPF0342 family
M0696_05520	COG4335	DNA alkylation repair
M0696_05525	COG0561	phosphatase activity
M0696_05530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M0696_05535	COG0475	glutathione-regulated potassium exporter activity
M0696_05540	COG0490	domain, Protein
M0696_05550	COG1024	Enoyl-CoA hydratase
M0696_05560	COG4152	abc transporter atp-binding protein
M0696_05565	COG1668	transmembrane transport
M0696_05570	COG0420	3'-5' exonuclease activity
M0696_05575	COG4717	serine-type aminopeptidase activity
M0696_05580	COG3481	metal-dependent phosphohydrolase, HD sub domain
M0696_05590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M0696_05620	COG1846	Transcriptional regulator
M0696_05625	COG4980	gas vesicle protein
M0696_05640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
M0696_05645	COG0537	adenosine 5'-monophosphoramidase activity
M0696_05650	COG1131	(ABC) transporter
M0696_05655	COG4473	ABC transporter
M0696_05665	COG1473	amidohydrolase
M0696_05670	COG3069	C4-dicarboxylate transmembrane transporter activity
M0696_05680	COG2329	Antibiotic biosynthesis monooxygenase
M0696_05685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_05690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
M0696_05695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M0696_05700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M0696_05705	COG1309	transcriptional regulator
M0696_05710	COG1511	domain protein
M0696_05715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M0696_05720	COG4377	Putative membrane peptidase family (DUF2324)
M0696_05725	COG1363	Peptidase, m42
M0696_05730	COG4405	Protein conserved in bacteria
M0696_05735	COG1301	dicarboxylic acid transport
M0696_05745	COG1234	tRNA 3'-trailer cleavage
M0696_05750	COG0095	Lipoate-protein ligase
M0696_05755	COG0702	epimerase
M0696_05760	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_05770	COG0501	Belongs to the peptidase M48B family
M0696_05785	COG0604	alcohol dehydrogenase
M0696_05790	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M0696_05795	COG0406	alpha-ribazole phosphatase activity
M0696_05800	COG0183	Belongs to the thiolase family
M0696_05805	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_05810	COG1268	BioY protein
M0696_05815	COG0840	transmembrane signaling receptor activity
M0696_05820	COG0723	plastoquinol--plastocyanin reductase activity
M0696_05820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_05825	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_05835	COG4903	ComK protein
M0696_05840	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_05850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_05865	COG0398	Pfam SNARE associated Golgi protein
M0696_05870	COG0681	Belongs to the peptidase S26 family
M0696_05875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M0696_05880	COG1846	Transcriptional regulator
M0696_05885	COG3180	Ammonia monooxygenase
M0696_05890	COG2814	Major facilitator Superfamily
M0696_05890	COG0477	Major facilitator Superfamily
M0696_05895	COG4533	DNA binding
M0696_05905	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M0696_05910	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
M0696_05915	COG1074	ATP-dependent DNA helicase activity
M0696_05920	COG0420	3'-5' exonuclease activity
M0696_05925	COG0419	ATPase involved in DNA repair
M0696_05930	COG1403	HNH endonuclease
M0696_05970	COG5337	Spore coat protein CotH
M0696_05975	COG0179	Fumarylacetoacetate (FAA) hydrolase
M0696_05985	COG1404	Belongs to the peptidase S8 family
M0696_05995	COG0367	asparagine synthase
M0696_06005	COG0534	Mate efflux family protein
M0696_06010	COG1917	Cupin 2, conserved barrel domain protein
M0696_06010	COG2207	Transcriptional regulator
M0696_06015	COG1609	Transcriptional regulator
M0696_06020	COG0673	inositol 2-dehydrogenase activity
M0696_06025	COG2318	DinB family
M0696_06035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_06040	COG1357	PFAM Pentapeptide repeats (8 copies)
M0696_06045	COG2267	carboxylic ester hydrolase activity
M0696_06050	COG0529	Catalyzes the synthesis of activated sulfate
M0696_06055	COG2046	Belongs to the sulfate adenylyltransferase family
M0696_06060	COG0175	sulfate reduction
M0696_06065	COG2045	Belongs to the ComB family
M0696_06070	COG1809	phosphosulfolactate synthase activity
M0696_06075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_06080	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_06085	COG2814	Major facilitator Superfamily
M0696_06090	COG0454	-acetyltransferase
M0696_06095	COG2153	protein acetylation
M0696_06100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M0696_06100	COG0646	methionine synthase
M0696_06105	COG1666	GTP binding
M0696_06120	COG1307	EDD domain protein, DegV family
M0696_06125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_06145	COG0561	phosphatase activity
M0696_06150	COG1073	alpha beta
M0696_06155	COG2151	metal-sulfur cluster biosynthetic enzyme
M0696_06165	COG0277	FAD linked oxidase domain protein
M0696_06170	COG2271	Major facilitator Superfamily
M0696_06175	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
M0696_06180	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M0696_06190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M0696_06195	COG0505	Belongs to the CarA family
M0696_06200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M0696_06205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M0696_06220	COG2267	carboxylic ester hydrolase activity
M0696_06230	COG1744	ABC transporter substrate-binding protein PnrA-like
M0696_06245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M0696_06250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M0696_06255	COG5504	Zn-dependent protease
M0696_06260	COG0444	Belongs to the ABC transporter superfamily
M0696_06265	COG4608	Belongs to the ABC transporter superfamily
M0696_06275	COG0601	transmembrane transport
M0696_06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M0696_06290	COG0180	Tryptophanyl-tRNA synthetase
M0696_06295	COG4166	transmembrane transport
M0696_06300	COG0601	transmembrane transport
M0696_06305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M0696_06310	COG0444	Belongs to the ABC transporter superfamily
M0696_06315	COG4608	Belongs to the ABC transporter superfamily
M0696_06320	COG2814	Major facilitator Superfamily
M0696_06325	COG0456	acetyltransferase
M0696_06330	COG1393	Belongs to the ArsC family
M0696_06335	COG0861	Integral membrane protein TerC family
M0696_06345	COG4862	establishment of competence for transformation
M0696_06355	COG4469	Competence protein
M0696_06360	COG1164	Oligoendopeptidase f
M0696_06370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M0696_06375	COG2346	COG2346, Truncated hemoglobins
M0696_06380	COG0741	lytic transglycosylase activity
M0696_06385	COG4116	CYTH
M0696_06395	COG2357	RelA SpoT domain protein
M0696_06400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M0696_06405	COG0564	pseudouridine synthase activity
M0696_06410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M0696_06415	COG0569	domain protein
M0696_06415	COG0475	glutathione-regulated potassium exporter activity
M0696_06420	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M0696_06425	COG0352	thiamine-phosphate diphosphorylase activity
M0696_06430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_06435	COG2104	thiamine diphosphate biosynthetic process
M0696_06440	COG2022	thiamine diphosphate biosynthetic process
M0696_06445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M0696_06450	COG0351	phosphomethylpyrimidine kinase
M0696_06455	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
M0696_06510	COG0210	DNA helicase
M0696_06520	COG2153	protein acetylation
M0696_06525	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M0696_06530	COG2382	esterase
M0696_06535	COG0626	cystathionine gamma-synthase activity
M0696_06540	COG0626	cystathionine gamma-synthase activity
M0696_06545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_06550	COG5505	Protein of unknown function (DUF819)
M0696_06565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M0696_06570	COG3711	transcriptional antiterminator
M0696_06570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_06575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_06575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_06575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_06580	COG1482	cell wall glycoprotein biosynthetic process
M0696_06600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M0696_06610	COG0109	protoheme IX farnesyltransferase activity
M0696_06620	COG0726	polysaccharide deacetylase
M0696_06635	COG5504	Zn-dependent protease
M0696_06640	COG2205	protein histidine kinase activity
M0696_06650	COG3383	formate dehydrogenase (NAD+) activity
M0696_06655	COG2427	Protein of unknown function (DUF1641)
M0696_06665	COG1051	belongs to the nudix hydrolase family
M0696_06675	COG2124	cytochrome p450
M0696_06680	COG1819	glycosyl
M0696_06690	COG1587	Uroporphyrinogen-III synthase
M0696_06695	COG0390	transport system, permease component
M0696_06700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M0696_06705	COG0697	spore germination
M0696_06710	COG4297	protein containing double-stranded beta helix domain
M0696_06720	COG1252	NADH dehydrogenase
M0696_06725	COG1904	glucuronate isomerase
M0696_06730	COG2211	Major facilitator Superfamily
M0696_06735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
M0696_06740	COG1063	alcohol dehydrogenase
M0696_06745	COG1312	Catalyzes the dehydration of D-mannonate
M0696_06750	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_06755	COG2271	Major facilitator Superfamily
M0696_06760	COG1609	Transcriptional regulator
M0696_06765	COG0246	Mannitol dehydrogenase
M0696_06770	COG2721	sulfolactate sulfo-lyase activity
M0696_06775	COG0730	response to heat
M0696_06780	COG2318	DinB family
M0696_06790	COG0457	Tetratricopeptide repeat
M0696_06800	COG2350	Protein conserved in bacteria
M0696_06805	COG1388	LysM domain
M0696_06805	COG3409	Peptidoglycan-binding domain 1 protein
M0696_06805	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_06815	COG4195	phage-related replication protein
M0696_06820	COG3546	catalase activity
M0696_06825	COG2856	Zn peptidase
M0696_06830	COG1396	sequence-specific DNA binding
M0696_06840	COG1522	sequence-specific DNA binding
M0696_06845	COG1484	DNA-dependent DNA replication
M0696_06865	COG1595	DNA-templated transcription, initiation
M0696_06870	COG5484	DNA packaging
M0696_06870	COG3728	DNA packaging
M0696_06875	COG1783	phage Terminase large subunit
M0696_06880	COG5518	Phage portal protein
M0696_06885	COG0338	D12 class N6 adenine-specific DNA methyltransferase
M0696_06890	COG4653	Phage capsid family
M0696_06940	COG3953	SLT domain
M0696_06940	COG5412	phage tail tape measure protein
M0696_06945	COG1652	LysM domain
M0696_06950	COG4193	domain, Protein
M0696_06960	COG3628	GPW Gp25 family protein
M0696_06965	COG3299	homolog of phage Mu protein gp47
M0696_06970	COG3778	Protein conserved in bacteria
M0696_07010	COG3409	Peptidoglycan-binding domain 1 protein
M0696_07010	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_07030	COG0306	phosphate transporter
M0696_07035	COG1392	Phosphate transport regulator
M0696_07040	COG0531	amino acid
M0696_07045	COG0346	lactoylglutathione lyase activity
M0696_07055	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
M0696_07060	COG0463	Glycosyl transferase, family 2
M0696_07070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_07075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M0696_07080	COG2362	D-Aminopeptidase
M0696_07085	COG0601	transmembrane transport
M0696_07090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M0696_07095	COG0444	Belongs to the ABC transporter superfamily
M0696_07100	COG4166	transmembrane transport
M0696_07105	COG1619	proteins homologs of microcin C7 resistance protein MccF
M0696_07110	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_07115	COG0791	NLP P60 protein
M0696_07120	COG4608	Belongs to the ABC transporter superfamily
M0696_07125	COG2706	6-phosphogluconolactonase activity
M0696_07135	COG1607	acyl-coa hydrolase
M0696_07140	COG1017	nitric oxide dioxygenase activity
M0696_07140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M0696_07150	COG2323	membrane
M0696_07155	COG2318	DinB family
M0696_07160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_07165	COG2076	Multidrug Resistance protein
M0696_07170	COG2076	Multidrug Resistance protein
M0696_07175	COG0788	formyltetrahydrofolate deformylase activity
M0696_07180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M0696_07185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
M0696_07190	COG1764	response to oxidative stress
M0696_07195	COG1846	Transcriptional regulator
M0696_07200	COG1764	response to oxidative stress
M0696_07205	COG0457	Tetratricopeptide repeat
M0696_07205	COG0463	Glycosyl transferase, family 2
M0696_07210	COG0590	tRNA wobble adenosine to inosine editing
M0696_07215	COG0406	alpha-ribazole phosphatase activity
M0696_07220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M0696_07225	COG1404	Belongs to the peptidase S8 family
M0696_07230	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_07235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M0696_07240	COG1122	ATPase activity
M0696_07245	COG4721	ABC-type cobalt transport system, permease component
M0696_07255	COG0745	RESPONSE REGULATOR receiver
M0696_07260	COG3850	Histidine kinase
M0696_07260	COG5002	protein histidine kinase activity
M0696_07265	COG3212	peptidase
M0696_07270	COG3212	peptidase
M0696_07280	COG2239	Acts as a magnesium transporter
M0696_07285	COG0789	Transcriptional regulator
M0696_07300	COG1846	Transcriptional regulator
M0696_07305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M0696_07310	COG0726	polysaccharide deacetylase
M0696_07315	COG1408	metallophosphoesterase
M0696_07325	COG0463	Glycosyl transferase, family 2
M0696_07330	COG3285	dna ligase
M0696_07330	COG1793	dna ligase
M0696_07335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
M0696_07340	COG5001	Diguanylate cyclase
M0696_07340	COG3300	MHYT domain
M0696_07345	COG0586	Pfam SNARE associated Golgi protein
M0696_07350	COG0861	Integral membrane protein TerC family
M0696_07355	COG1191	sigma factor activity
M0696_07375	COG0501	Belongs to the peptidase M48B family
M0696_07380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M0696_07395	COG3594	Acyltransferase
M0696_07400	COG5002	protein histidine kinase activity
M0696_07405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M0696_07415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
M0696_07420	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
M0696_07425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M0696_07430	COG0436	Aminotransferase
M0696_07435	COG1850	ribulose-bisphosphate carboxylase activity
M0696_07440	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
M0696_07445	COG0235	Class ii aldolase
M0696_07450	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
M0696_07455	COG3339	Conserved Protein
M0696_07470	COG3852	Histidine kinase
M0696_07475	COG1846	Transcriptional regulator
M0696_07480	COG1360	Flagellar Motor Protein
M0696_07485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M0696_07490	COG0542	response to heat
M0696_07495	COG3949	Membrane
M0696_07500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M0696_07505	COG0720	synthase
M0696_07510	COG0602	queuosine metabolic process
M0696_07515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
M0696_07520	COG1733	regulation of RNA biosynthetic process
M0696_07525	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_07540	COG1388	LysM domain
M0696_07540	COG4641	Protein conserved in bacteria
M0696_07545	COG1388	LysM domain
M0696_07550	COG3858	chitin binding
M0696_07560	COG4873	Protein conserved in bacteria
M0696_07570	COG3773	Cell wall hydrolase
M0696_07575	COG2244	polysaccharide biosynthetic process
M0696_07580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_07585	COG2217	Heavy metal translocating P-type atpase
M0696_07595	COG0006	proline dipeptidase activity
M0696_07600	COG1609	Transcriptional regulator
M0696_07605	COG3711	transcriptional antiterminator
M0696_07610	COG1263	PTS System
M0696_07610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_07610	COG2190	(PTS) system
M0696_07615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_07620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M0696_07630	COG1533	DNA photolyase activity
M0696_07635	COG0456	acetyltransferase
M0696_07640	COG0840	transmembrane signaling receptor activity
M0696_07645	COG2084	Dehydrogenase
M0696_07650	COG4257	antibiotic catabolic process
M0696_07655	COG2340	Cysteine-rich secretory protein family
M0696_07660	COG0768	penicillin binding
M0696_07665	COG4191	Histidine kinase
M0696_07670	COG0436	Aminotransferase
M0696_07680	COG0835	chemotaxis
M0696_07680	COG0784	Response regulator, receiver
M0696_07690	COG2814	Major facilitator Superfamily
M0696_07695	COG1376	ErfK ybiS ycfS ynhG family protein
M0696_07700	COG1408	metallophosphoesterase
M0696_07705	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_07710	COG2200	EAL domain
M0696_07715	COG4703	Protein of unknown function (DUF1797)
M0696_07720	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M0696_07730	COG0517	IMP dehydrogenase activity
M0696_07735	COG0583	DNA-binding transcription factor activity
M0696_07740	COG0716	FMN binding
M0696_07750	COG0716	FMN binding
M0696_07755	COG2171	N-acyltransferase activity
M0696_07760	COG1473	amidohydrolase
M0696_07770	COG0668	transmembrane transport
M0696_07775	COG0450	alkyl hydroperoxide reductase
M0696_07780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_07795	COG0746	molybdenum cofactor guanylyltransferase activity
M0696_07800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M0696_07805	COG0303	'Molybdopterin
M0696_07810	COG1763	Mo-molybdopterin cofactor biosynthetic process
M0696_07815	COG0314	molybdopterin synthase activity
M0696_07820	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M0696_07825	COG1132	(ABC) transporter
M0696_07830	COG1132	(ABC) transporter
M0696_07840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M0696_07845	COG1136	(ABC) transporter
M0696_07850	COG0577	efflux transmembrane transporter activity
M0696_07855	COG1349	DNA-binding transcription factor activity
M0696_07860	COG1105	Belongs to the carbohydrate kinase PfkB family
M0696_07865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_07865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_07865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_07870	COG0681	Belongs to the peptidase S26 family
M0696_07880	COG0488	(ABC) transporter
M0696_07885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M0696_07890	COG2309	aminopeptidase activity
M0696_07900	COG1077	Cell shape determining protein MreB Mrl
M0696_07905	COG2002	toxin-antitoxin pair type II binding
M0696_07910	COG3852	Histidine kinase
M0696_07915	COG2105	PFAM AIG2 family protein
M0696_07915	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
M0696_07920	COG0569	domain protein
M0696_07925	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M0696_07930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M0696_07935	COG5503	Protein of unknown function (DUF1447)
M0696_07940	COG0561	phosphatase activity
M0696_07945	COG0242	peptide deformylase activity
M0696_07955	COG0497	DNA recombination
M0696_07960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M0696_07965	COG0022	dehydrogenase e1 component
M0696_07970	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_07975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M0696_07980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_07990	COG1982	Orn Lys Arg decarboxylase major
M0696_07995	COG4476	Belongs to the UPF0223 family
M0696_08000	COG4493	Belongs to the UPF0637 family
M0696_08010	COG0483	inositol monophosphate 1-phosphatase activity
M0696_08020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M0696_08040	COG1595	DNA-templated transcription, initiation
M0696_08060	COG1217	gtp-binding protein TYPA
M0696_08070	COG4896	Protein conserved in bacteria
M0696_08080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M0696_08085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M0696_08090	COG2066	Belongs to the glutaminase family
M0696_08095	COG4838	Belongs to the UPF0358 family
M0696_08100	COG0772	Belongs to the SEDS family
M0696_08105	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M0696_08110	COG1612	heme a metabolic process
M0696_08115	COG0109	protoheme IX farnesyltransferase activity
M0696_08120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M0696_08120	COG2010	Cytochrome c
M0696_08125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M0696_08130	COG1845	cytochrome c oxidase, subunit III
M0696_08135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M0696_08140	COG3336	cytochrome c oxidase
M0696_08150	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M0696_08155	COG2340	Cysteine-rich secretory protein family
M0696_08170	COG3679	Belongs to the UPF0342 family
M0696_08175	COG4471	UPF0298 protein
M0696_08180	COG0742	ribosomal rna small subunit methyltransferase
M0696_08185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
M0696_08190	COG3314	Sporulation integral membrane protein YlbJ
M0696_08195	COG1752	Esterase of the alpha-beta hydrolase superfamily
M0696_08200	COG3480	Lon protease (S16) C-terminal proteolytic domain
M0696_08205	COG1323	Belongs to the UPF0348 family
M0696_08215	COG1399	metal-binding, possibly nucleic acid-binding protein
M0696_08230	COG0454	-acetyltransferase
M0696_08235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M0696_08240	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
M0696_08245	COG2001	Belongs to the MraZ family
M0696_08250	COG0275	rRNA processing
M0696_08255	COG4839	cell division protein FtsL
M0696_08260	COG0768	penicillin binding
M0696_08265	COG0768	penicillin binding
M0696_08270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M0696_08275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M0696_08280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M0696_08285	COG0772	Belongs to the SEDS family
M0696_08290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M0696_08295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M0696_08300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M0696_08305	COG3879	Bacterial protein of unknown function (DUF881)
M0696_08310	COG3879	Bacterial protein of unknown function (DUF881)
M0696_08315	COG3856	small basic protein
M0696_08320	COG0849	cell division
M0696_08325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M0696_08330	COG4412	M6 family metalloprotease domain protein
M0696_08330	COG1404	Belongs to the peptidase S8 family
M0696_08340	COG1191	sigma factor activity
M0696_08345	COG1191	sigma factor activity
M0696_08350	COG1119	ATPase activity
M0696_08355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_08360	COG1873	PFAM PRC-barrel domain
M0696_08365	COG1496	oxidoreductase activity
M0696_08370	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M0696_08375	COG1799	cell septum assembly
M0696_08380	COG0762	integral membrane protein
M0696_08385	COG2302	S4 RNA-binding domain
M0696_08390	COG3599	regulation of cell shape
M0696_08395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M0696_08400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M0696_08405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
M0696_08410	COG0564	pseudouridine synthase activity
M0696_08415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
M0696_08420	COG2233	PERMEase
M0696_08425	COG0540	Belongs to the ATCase OTCase family
M0696_08430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M0696_08435	COG0505	Belongs to the CarA family
M0696_08440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M0696_08445	COG0543	2 iron, 2 sulfur cluster binding
M0696_08450	COG0167	dihydroorotate dehydrogenase activity
M0696_08455	COG0284	orotidine-5'-phosphate decarboxylase activity
M0696_08460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M0696_08465	COG0175	sulfate reduction
M0696_08470	COG0306	phosphate transporter
M0696_08475	COG2046	Belongs to the sulfate adenylyltransferase family
M0696_08480	COG0529	Catalyzes the synthesis of activated sulfate
M0696_08485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M0696_08490	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
M0696_08495	COG1648	precorrin-2 dehydrogenase activity
M0696_08500	COG1293	RNA-binding protein homologous to eukaryotic snRNP
M0696_08505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M0696_08510	COG1561	YicC-like family, N-terminal region
M0696_08520	COG0194	GDP metabolic process
M0696_08525	COG1758	RNA polymerase activity
M0696_08530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M0696_08535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M0696_08540	COG0242	peptide deformylase activity
M0696_08545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M0696_08550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M0696_08550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M0696_08555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
M0696_08560	COG0631	protein serine/threonine phosphatase activity
M0696_08565	COG0515	serine threonine protein kinase
M0696_08565	COG2815	serine threonine protein kinase
M0696_08570	COG1162	GTPase activity
M0696_08575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M0696_08580	COG1564	THIamine pyrophosphokinase
M0696_08590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
M0696_08595	COG1302	Protein conserved in bacteria
M0696_08600	COG1461	Dihydroxyacetone kinase
M0696_08605	COG1760	l-serine dehydratase
M0696_08610	COG1760	l-serine dehydratase
M0696_08615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M0696_08620	COG1349	DNA-binding transcription factor activity
M0696_08620	COG2050	protein possibly involved in aromatic compounds catabolism
M0696_08625	COG0416	fatty acid biosynthetic process
M0696_08630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M0696_08635	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_08645	COG0571	ribonuclease III activity
M0696_08650	COG1196	nuclear chromosome segregation
M0696_08655	COG0552	protein localization to endoplasmic reticulum
M0696_08665	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
M0696_08670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M0696_08675	COG0228	four-way junction DNA binding
M0696_08680	COG1837	Belongs to the UPF0109 family
M0696_08690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M0696_08695	COG0336	Belongs to the RNA methyltransferase TrmD family
M0696_08700	COG0335	large ribosomal subunit rRNA binding
M0696_08705	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M0696_08710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M0696_08720	COG2257	FlhB HrpN YscU SpaS Family
M0696_08725	COG0045	succinate-CoA ligase (ADP-forming) activity
M0696_08730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M0696_08735	COG0758	DNA mediated transformation
M0696_08740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M0696_08745	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
M0696_08750	COG4974	Belongs to the 'phage' integrase family
M0696_08755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
M0696_08760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
M0696_08765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M0696_08770	COG1815	bacterial-type flagellum-dependent cell motility
M0696_08775	COG1558	bacterial-type flagellum-dependent cell motility
M0696_08780	COG1677	Flagellar hook-basal body complex protein FliE
M0696_08785	COG1766	The M ring may be actively involved in energy transduction
M0696_08790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M0696_08795	COG1317	bacterial-type flagellum organization
M0696_08800	COG1157	protein secretion by the type III secretion system
M0696_08805	COG2882	bacterial-type flagellum organization
M0696_08810	COG3334	PFAM MgtE intracellular
M0696_08815	COG3144	bacterial-type flagellum assembly
M0696_08820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M0696_08825	COG4786	Flagellar basal body rod
M0696_08830	COG1582	Flagellar protein (FlbD)
M0696_08835	COG1580	Controls the rotational direction of flagella during chemotaxis
M0696_08840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M0696_08845	COG1776	CheC inhibitor of MCP methylation
M0696_08845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M0696_08850	COG2201	protein-glutamate methylesterase activity
M0696_08855	COG3190	flagellar
M0696_08860	COG1338	Plays a role in the flagellum-specific transport system
M0696_08865	COG1987	bacterial-type flagellum assembly
M0696_08870	COG1684	flagellar biosynthetic protein fliR
M0696_08875	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M0696_08880	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M0696_08885	COG1419	protein localization to endoplasmic reticulum
M0696_08890	COG0455	bacterial-type flagellum organization
M0696_08895	COG2201	protein-glutamate methylesterase activity
M0696_08900	COG2198	Histidine kinase
M0696_08900	COG0643	Histidine kinase
M0696_08905	COG0835	chemotaxis
M0696_08910	COG1776	CheC inhibitor of MCP methylation
M0696_08915	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
M0696_08920	COG1191	sigma factor activity
M0696_08930	COG0052	Belongs to the universal ribosomal protein uS2 family
M0696_08935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
M0696_08940	COG0528	UMP kinase activity
M0696_08945	COG0233	cytoplasmic translational termination
M0696_08950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M0696_08955	COG4589	Belongs to the CDS family
M0696_08960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
M0696_08965	COG0750	zinc metalloprotease
M0696_08970	COG0442	prolyl-tRNA aminoacylation
M0696_08975	COG2176	DNA-directed DNA polymerase activity
M0696_08980	COG0779	Required for maturation of 30S ribosomal subunits
M0696_08985	COG0195	Participates in both transcription termination and antitermination
M0696_08990	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M0696_08995	COG1358	cellular component organization or biogenesis
M0696_09000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
M0696_09005	COG1550	Protein conserved in bacteria
M0696_09010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
M0696_09015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M0696_09020	COG0196	riboflavin kinase activity
M0696_09030	COG1185	polyribonucleotide nucleotidyltransferase activity
M0696_09035	COG0726	polysaccharide deacetylase
M0696_09040	COG0612	Peptidase, M16
M0696_09045	COG1873	PFAM PRC-barrel domain
M0696_09050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M0696_09055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M0696_09060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M0696_09065	COG0527	aspartate kinase activity
M0696_09070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M0696_09075	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M0696_09080	COG0740	serine-type endopeptidase activity
M0696_09090	COG1674	ftsk spoiiie
M0696_09090	COG4980	gas vesicle protein
M0696_09095	COG2188	Transcriptional regulator
M0696_09100	COG2814	Major facilitator Superfamily
M0696_09105	COG0612	Peptidase, M16
M0696_09110	COG0612	Peptidase, M16
M0696_09115	COG0300	oxidoreductase activity
M0696_09130	COG1426	Protein conserved in bacteria
M0696_09135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M0696_09140	COG1058	Belongs to the CinA family
M0696_09140	COG1546	Belongs to the CinA family
M0696_09145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M0696_09150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_09155	COG1418	mRNA catabolic process
M0696_09160	COG1692	metallophosphoesterase
M0696_09165	COG2359	stage V sporulation protein S
M0696_09170	COG1063	alcohol dehydrogenase
M0696_09175	COG0156	8-amino-7-oxononanoate synthase activity
M0696_09180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M0696_09185	COG4550	Control of competence regulator ComK, YlbF/YmcA
M0696_09195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
M0696_09200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M0696_09215	COG3226	Transcriptional regulator
M0696_09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_09230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M0696_09235	COG3321	synthase
M0696_09240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M0696_09240	COG2070	2-Nitropropane dioxygenase
M0696_09245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_09250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M0696_09255	COG3425	synthase
M0696_09260	COG1024	Enoyl-CoA hydratase
M0696_09265	COG1024	Enoyl-CoA hydratase
M0696_09270	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_09270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09270	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_09270	COG3321	synthase
M0696_09270	COG0300	oxidoreductase activity
M0696_09275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_09275	COG0300	oxidoreductase activity
M0696_09275	COG3321	synthase
M0696_09275	COG4221	oxidoreductase activity
M0696_09280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_09280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09280	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_09280	COG3321	synthase
M0696_09280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_09285	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_09285	COG4221	oxidoreductase activity
M0696_09285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09285	COG3321	synthase
M0696_09290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_09290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M0696_09290	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M0696_09290	COG3321	synthase
M0696_09295	COG2124	cytochrome p450
M0696_09305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_09310	COG1404	Belongs to the peptidase S8 family
M0696_09320	COG4195	phage-related replication protein
M0696_09325	COG1764	response to oxidative stress
M0696_09350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
M0696_09355	COG1923	regulation of RNA biosynthetic process
M0696_09370	COG1780	Probably involved in ribonucleotide reductase function
M0696_09375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M0696_09380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M0696_09385	COG4112	unkown
M0696_09390	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_09395	COG0464	growth
M0696_09400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M0696_09405	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M0696_09410	COG0789	Transcriptional regulator
M0696_09415	COG0174	glutamine synthetase
M0696_09440	COG3403	YqcI/YcgG family
M0696_09445	COG0135	phosphoribosylanthranilate isomerase activity
M0696_09460	COG2273	Hydrolase Family 16
M0696_09485	COG0726	polysaccharide deacetylase
M0696_09490	COG2211	Major facilitator Superfamily
M0696_09495	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_09505	COG2115	Belongs to the xylose isomerase family
M0696_09510	COG1070	Carbohydrate kinase
M0696_09515	COG1525	nuclease
M0696_09525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M0696_09535	COG0756	dUTP diphosphatase activity
M0696_09585	COG3832	glyoxalase III activity
M0696_09600	COG2059	Chromate
M0696_09605	COG0697	spore germination
M0696_09610	COG0531	amino acid
M0696_09640	COG4195	phage-related replication protein
M0696_09650	COG0346	lactoylglutathione lyase activity
M0696_09655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M0696_09660	COG1388	LysM domain
M0696_09665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M0696_09670	COG4224	UPF0291 protein
M0696_09675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M0696_09685	COG3763	UPF0154 protein
M0696_09695	COG0785	Cytochrome C biogenesis protein
M0696_09700	COG2201	protein-glutamate methylesterase activity
M0696_09705	COG4846	Membrane protein involved in cytochrome C biogenesis
M0696_09715	COG0071	Belongs to the small heat shock protein (HSP20) family
M0696_09730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M0696_09735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_09755	COG0824	Thioesterase
M0696_09765	COG4841	protein insertion into membrane
M0696_09770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M0696_09775	COG1832	CoA-binding protein
M0696_09780	COG0187	DNA topoisomerase II activity
M0696_09785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M0696_09795	COG1115	amino acid carrier protein
M0696_09800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
M0696_09810	COG5520	Belongs to the glycosyl hydrolase 30 family
M0696_09815	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_09820	COG2246	polysaccharide biosynthetic process
M0696_09825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M0696_09830	COG0586	Pfam SNARE associated Golgi protein
M0696_09835	COG2404	hydrolase activity, acting on ester bonds
M0696_09840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M0696_09845	COG1024	Enoyl-CoA hydratase
M0696_09850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M0696_09855	COG0511	ligase activity, forming carbon-carbon bonds
M0696_09860	COG0439	Biotin carboxylase
M0696_09865	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_09870	COG1960	acyl-CoA dehydrogenase activity
M0696_09880	COG1309	transcriptional regulator
M0696_09890	COG1649	PFAM Uncharacterised BCR, COG1649
M0696_09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M0696_09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_09925	COG2027	D-alanyl-D-alanine carboxypeptidase
M0696_09930	COG2017	converts alpha-aldose to the beta-anomer
M0696_09935	COG0534	Mate efflux family protein
M0696_09950	COG0582	viral genome integration into host DNA
M0696_09955	COG0166	Belongs to the GPI family
M0696_09960	COG0405	Gamma-glutamyltransferase
M0696_09965	COG0583	DNA-binding transcription factor activity
M0696_09970	COG0604	alcohol dehydrogenase
M0696_09975	COG0493	'glutamate synthase
M0696_09980	COG0069	glutamate synthase activity
M0696_09980	COG0070	glutamate synthase
M0696_09980	COG0067	glutamate synthase
M0696_09985	COG0583	DNA-binding transcription factor activity
M0696_09990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M0696_10010	COG0300	oxidoreductase activity
M0696_10015	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M0696_10025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_10030	COG2814	Major facilitator Superfamily
M0696_10035	COG1070	Carbohydrate kinase
M0696_10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M0696_10045	COG0243	molybdopterin cofactor binding
M0696_10055	COG1082	Xylose isomerase domain protein TIM barrel
M0696_10075	COG2368	4-hydroxyphenylacetate
M0696_10080	COG4305	rare lipoprotein A
M0696_10085	COG3619	membrane
M0696_10095	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_10110	COG2135	peptidase activity
M0696_10145	COG2720	vancomycin resistance protein
M0696_10155	COG3655	Transcriptional regulator
M0696_10160	COG3739	integral membrane protein
M0696_10165	COG0583	DNA-binding transcription factor activity
M0696_10170	COG0697	spore germination
M0696_10190	COG0693	protein deglycase activity
M0696_10195	COG2367	Beta-lactamase
M0696_10205	COG3397	chitin binding
M0696_10210	COG2318	DinB family
M0696_10215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_10220	COG3848	Pyruvate phosphate dikinase
M0696_10220	COG0574	Belongs to the PEP-utilizing enzyme family
M0696_10250	COG1231	oxidoreductase activity
M0696_10255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_10260	COG0662	Cupin 2, conserved barrel domain protein
M0696_10260	COG2207	Transcriptional regulator
M0696_10265	COG0456	acetyltransferase
M0696_10270	COG1309	transcriptional regulator
M0696_10275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_10280	COG3708	Transcriptional regulator
M0696_10285	COG2378	regulation of single-species biofilm formation
M0696_10295	COG0640	Transcriptional regulator
M0696_10300	COG0741	lytic transglycosylase activity
M0696_10305	COG2322	membrane
M0696_10325	COG3239	Fatty acid desaturase
M0696_10330	COG4585	Histidine kinase
M0696_10335	COG2197	response regulator
M0696_10340	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_10345	COG3584	3D domain protein
M0696_10345	COG1388	LysM domain
M0696_10360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M0696_10365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M0696_10385	COG1012	belongs to the aldehyde dehydrogenase family
M0696_10390	COG1657	PFAM Prenyltransferase squalene oxidase
M0696_10395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M0696_10400	COG0733	neurotransmitter:sodium symporter activity
M0696_10405	COG0385	Bile acid
M0696_10410	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_10415	COG0567	Dehydrogenase, E1 component
M0696_10420	COG4548	von Willebrand factor, type A
M0696_10425	COG0714	Associated with various cellular activities
M0696_10430	COG2032	superoxide dismutase activity
M0696_10435	COG1388	LysM domain
M0696_10435	COG0791	NLP P60 protein
M0696_10440	COG1819	glycosyl
M0696_10445	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M0696_10450	COG0534	Mate efflux family protein
M0696_10455	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_10460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M0696_10465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M0696_10475	COG2962	Rard protein
M0696_10490	COG2610	gluconate transmembrane transporter activity
M0696_10495	COG1942	4-Oxalocrotonate Tautomerase
M0696_10505	COG1733	regulation of RNA biosynthetic process
M0696_10510	COG0778	Nitroreductase
M0696_10515	COG0400	carboxylic ester hydrolase activity
M0696_10520	COG0346	lactoylglutathione lyase activity
M0696_10530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_10535	COG0793	Belongs to the peptidase S41A family
M0696_10535	COG3409	Peptidoglycan-binding domain 1 protein
M0696_10540	COG2226	methyltransferase
M0696_10550	COG1876	peptidase activity
M0696_10555	COG0813	purine-nucleoside phosphorylase activity
M0696_10570	COG0671	phosphoesterase, PA-phosphatase related
M0696_10590	COG4479	Belongs to the UPF0346 family
M0696_10600	COG1509	lysine 2,3-aminomutase activity
M0696_10605	COG0456	acetyltransferase
M0696_10610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_10615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M0696_10620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M0696_10625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M0696_10635	COG0456	acetyltransferase
M0696_10640	COG0463	Glycosyl transferase, family 2
M0696_10655	COG4641	Protein conserved in bacteria
M0696_10660	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
M0696_10665	COG1086	Polysaccharide biosynthesis protein
M0696_10675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M0696_10680	COG1846	Transcriptional regulator
M0696_10685	COG0534	Mate efflux family protein
M0696_10695	COG4698	Protein conserved in bacteria
M0696_10700	COG2755	lipolytic protein G-D-S-L family
M0696_10705	COG1999	signal sequence binding
M0696_10715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M0696_10720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M0696_10725	COG1272	protein, Hemolysin III
M0696_10730	COG0204	Acyl-transferase
M0696_10735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M0696_10745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M0696_10755	COG2521	methyltransferase
M0696_10755	COG2136	Putative SAM-dependent methyltransferase
M0696_10765	COG0129	dihydroxy-acid dehydratase activity
M0696_10770	COG1413	lyase activity
M0696_10775	COG1418	mRNA catabolic process
M0696_10780	COG0386	Belongs to the glutathione peroxidase family
M0696_10785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
M0696_10790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M0696_10800	COG1278	Cold shock
M0696_10820	COG0328	RNA-DNA hybrid ribonuclease activity
M0696_10825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M0696_10830	COG0328	RNA-DNA hybrid ribonuclease activity
M0696_10840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M0696_10855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M0696_10865	COG1755	Isoprenylcysteine carboxyl methyltransferase
M0696_10870	COG3424	synthase
M0696_10875	COG2233	PERMEase
M0696_10880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M0696_10885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M0696_10895	COG0800	Aldolase
M0696_10900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_10905	COG1609	Transcriptional regulator
M0696_10910	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
M0696_10915	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_10920	COG1199	ATP-dependent helicase activity
M0696_10935	COG0116	Belongs to the methyltransferase superfamily
M0696_10950	COG4474	Belongs to the UPF0398 family
M0696_10965	COG3359	exonuclease
M0696_10970	COG1111	helicase
M0696_10970	COG1205	dead DEAH box helicase
M0696_10975	COG2190	(PTS) system
M0696_10980	COG0071	Belongs to the small heat shock protein (HSP20) family
M0696_11015	COG3331	DNA recombination
M0696_11020	COG4499	WXG100 protein secretion system (Wss), protein YukC
M0696_11020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_11030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M0696_11035	COG3935	DnaD domain protein
M0696_11040	COG0017	Asparaginyl-tRNA synthetase
M0696_11045	COG0436	Aminotransferase
M0696_11050	COG5353	protein conserved in bacteria
M0696_11060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M0696_11060	COG1199	ATP-dependent helicase activity
M0696_11065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
M0696_11070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
M0696_11075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
M0696_11085	COG0617	tRNA 3'-terminal CCA addition
M0696_11090	COG0438	transferase activity, transferring glycosyl groups
M0696_11095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M0696_11100	COG1803	Methylglyoxal synthase
M0696_11105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
M0696_11110	COG1694	Mazg nucleotide pyrophosphohydrolase
M0696_11115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_11125	COG4347	Protein of unknown function (DUF1405)
M0696_11130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M0696_11130	COG2010	Cytochrome c
M0696_11135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M0696_11140	COG0723	plastoquinol--plastocyanin reductase activity
M0696_11150	COG5582	Belongs to the UPF0302 family
M0696_11155	COG0457	Tetratricopeptide repeat
M0696_11160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M0696_11165	COG0287	Prephenate dehydrogenase
M0696_11170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M0696_11175	COG0159	tryptophan synthase activity
M0696_11180	COG0133	tryptophan synthase activity
M0696_11185	COG0135	phosphoribosylanthranilate isomerase activity
M0696_11195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M0696_11200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M0696_11205	COG4401	Chorismate mutase type I
M0696_11210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
M0696_11215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
M0696_11220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M0696_11225	COG0105	UTP biosynthetic process
M0696_11230	COG0142	geranyltranstransferase activity
M0696_11235	COG2226	methyltransferase
M0696_11240	COG0142	geranyltranstransferase activity
M0696_11250	COG0302	gtp cyclohydrolase
M0696_11255	COG0776	regulation of translation
M0696_11260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M0696_11275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
M0696_11280	COG1160	GTP binding
M0696_11305	COG1304	FMN binding
M0696_11310	COG0539	negative regulation of cytoplasmic translation
M0696_11315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
M0696_11325	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
M0696_11330	COG2959	enzyme of heme biosynthesis
M0696_11335	COG3409	Peptidoglycan-binding domain 1 protein
M0696_11335	COG3773	Cell wall hydrolase
M0696_11340	COG2339	peptidase activity
M0696_11345	COG0492	ferredoxin-NADP+ reductase activity
M0696_11350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M0696_11355	COG4862	establishment of competence for transformation
M0696_11360	COG1408	metallophosphoesterase
M0696_11370	COG1388	LysM domain
M0696_11375	COG1266	CAAX protease self-immunity
M0696_11380	COG0514	ATP-dependent DNA helicase (RecQ)
M0696_11385	COG4955	Helix-turn-helix domain
M0696_11390	COG1141	Ferredoxin
M0696_11395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M0696_11400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M0696_11405	COG0710	3-dehydroquinate dehydratase activity
M0696_11415	COG1595	DNA-templated transcription, initiation
M0696_11420	COG5002	protein histidine kinase activity
M0696_11425	COG0745	RESPONSE REGULATOR receiver
M0696_11430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M0696_11435	COG1333	cytochrome c biogenesis protein
M0696_11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_11445	COG1187	pseudouridine synthase activity
M0696_11450	COG0700	Nucleoside recognition
M0696_11455	COG2715	membrane protein required for spore maturation
M0696_11460	COG1686	Belongs to the peptidase S11 family
M0696_11470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M0696_11475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M0696_11480	COG1547	Domain of unknown function (DUF309)
M0696_11485	COG0456	acetyltransferase
M0696_11490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
M0696_11495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M0696_11495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M0696_11500	COG0307	riboflavin synthase, alpha
M0696_11505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M0696_11505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M0696_11515	COG0681	Belongs to the peptidase S26 family
M0696_11530	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
M0696_11540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M0696_11545	COG4086	secreted protein
M0696_11550	COG0019	diaminopimelate decarboxylase activity
M0696_11555	COG0697	spore germination
M0696_11570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M0696_11590	COG1191	sigma factor activity
M0696_11595	COG2172	sigma factor antagonist activity
M0696_11600	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_11605	COG1686	Belongs to the peptidase S11 family
M0696_11610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M0696_11615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
M0696_11620	COG4974	Belongs to the 'phage' integrase family
M0696_11630	COG0735	belongs to the Fur family
M0696_11635	COG1300	Membrane
M0696_11645	COG0281	malic enzyme
M0696_11650	COG1757	Na H antiporter
M0696_11655	COG1027	Aspartate ammonia-lyase
M0696_11660	COG0252	asparaginase activity
M0696_11665	COG1396	sequence-specific DNA binding
M0696_11670	COG1379	DNA repair
M0696_11675	COG0494	nUDIX hydrolase
M0696_11685	COG0667	Aldo Keto reductase
M0696_11695	COG1073	alpha beta
M0696_11700	COG0772	Belongs to the SEDS family
M0696_11705	COG0772	Belongs to the SEDS family
M0696_11710	COG3339	Conserved Protein
M0696_11720	COG4918	Iron-sulphur cluster biosynthesis
M0696_11725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M0696_11725	COG0456	acetyltransferase
M0696_11730	COG2329	Antibiotic biosynthesis monooxygenase
M0696_11735	COG0456	acetyltransferase
M0696_11745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M0696_11755	COG2211	Major facilitator Superfamily
M0696_11765	COG0346	lactoylglutathione lyase activity
M0696_11770	COG1072	(Pantothenic acid kinase))
M0696_11775	COG3048	D-serine ammonia-lyase activity
M0696_11780	COG0300	oxidoreductase activity
M0696_11785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_11790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M0696_11795	COG4187	Peptidase family M20/M25/M40
M0696_11800	COG1902	pentaerythritol trinitrate reductase activity
M0696_11805	COG0596	Alpha beta hydrolase
M0696_11815	COG1234	tRNA 3'-trailer cleavage
M0696_11820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M0696_11825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M0696_11830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M0696_11840	COG0706	membrane insertase activity
M0696_11845	COG3361	conserved protein (COG2071)
M0696_11850	COG2195	Cleaves the N-terminal amino acid of tripeptides
M0696_11855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M0696_11860	COG0346	lactoylglutathione lyase activity
M0696_11870	COG1376	ErfK ybiS ycfS ynhG family protein
M0696_11875	COG4129	membrane
M0696_11880	COG1126	abc transporter atp-binding protein
M0696_11885	COG0765	amino acid transport
M0696_11890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_11900	COG1597	lipid kinase activity
M0696_11905	COG2814	Major facilitator Superfamily
M0696_11910	COG4978	Transcriptional regulator
M0696_11910	COG0789	Transcriptional regulator
M0696_11915	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_11920	COG0022	dehydrogenase e1 component
M0696_11925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M0696_11930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M0696_11935	COG3426	butyrate kinase activity
M0696_11940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M0696_11945	COG0280	phosphate acetyltransferase
M0696_11950	COG3829	transcription factor binding
M0696_11950	COG3290	protein histidine kinase activity
M0696_11960	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M0696_11965	COG2079	MmgE PrpD family protein
M0696_11970	COG0372	Belongs to the citrate synthase family
M0696_11975	COG1960	acyl-CoA dehydrogenase activity
M0696_11980	COG1250	3-hydroxyacyl-CoA dehydrogenase
M0696_11985	COG0183	Belongs to the thiolase family
M0696_11990	COG0584	glycerophosphoryl diester phosphodiesterase
M0696_11995	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_12005	COG1902	pentaerythritol trinitrate reductase activity
M0696_12010	COG0745	RESPONSE REGULATOR receiver
M0696_12015	COG0750	zinc metalloprotease
M0696_12020	COG0497	DNA recombination
M0696_12025	COG1438	arginine binding
M0696_12030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M0696_12035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
M0696_12040	COG0142	geranyltranstransferase activity
M0696_12045	COG1722	exodeoxyribonuclease VII activity
M0696_12050	COG1570	exodeoxyribonuclease VII activity
M0696_12055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
M0696_12060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M0696_12065	COG1302	Protein conserved in bacteria
M0696_12070	COG0439	Biotin carboxylase
M0696_12075	COG0511	ligase activity, forming carbon-carbon bonds
M0696_12115	COG3854	ATPases associated with a variety of cellular activities
M0696_12125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
M0696_12130	COG0006	proline dipeptidase activity
M0696_12135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
M0696_12145	COG3872	metal-dependent enzyme
M0696_12155	COG1752	Esterase of the alpha-beta hydrolase superfamily
M0696_12160	COG1321	iron dependent repressor
M0696_12165	COG0095	Lipoate-protein ligase
M0696_12170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_12175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M0696_12180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M0696_12185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
M0696_12190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M0696_12205	COG1396	sequence-specific DNA binding
M0696_12215	COG0681	Belongs to the peptidase S26 family
M0696_12240	COG4940	Competence protein ComGF
M0696_12250	COG4970	Tfp pilus assembly protein FimT
M0696_12255	COG4537	Required for transformation and DNA binding
M0696_12260	COG1459	type II secretion system
M0696_12265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M0696_12270	COG0517	IMP dehydrogenase activity
M0696_12275	COG0598	Magnesium transport protein CorA
M0696_12280	COG1253	flavin adenine dinucleotide binding
M0696_12285	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_12295	COG1393	Belongs to the ArsC family
M0696_12305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_12315	COG0011	TIGRFAM Protein of
M0696_12325	COG2866	Carboxypeptidase
M0696_12330	COG1368	sulfuric ester hydrolase activity
M0696_12335	COG1940	carbohydrate kinase activity
M0696_12345	COG0457	Tetratricopeptide repeat
M0696_12345	COG0705	Rhomboid family
M0696_12355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M0696_12365	COG0438	transferase activity, transferring glycosyl groups
M0696_12380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M0696_12385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M0696_12390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M0696_12395	COG0581	inorganic phosphate transmembrane transporter activity
M0696_12400	COG0573	inorganic phosphate transmembrane transporter activity
M0696_12405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M0696_12410	COG0768	penicillin binding
M0696_12415	COG0477	Major facilitator Superfamily
M0696_12420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M0696_12425	COG2839	Protein conserved in bacteria
M0696_12430	COG5521	maltodextrose utilization protein MalA
M0696_12440	COG1388	LysM domain
M0696_12445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
M0696_12450	COG4709	membrane
M0696_12455	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
M0696_12460	COG0735	belongs to the Fur family
M0696_12465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_12475	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
M0696_12480	COG0513	Belongs to the DEAD box helicase family
M0696_12490	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
M0696_12495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M0696_12500	COG2384	SAM-dependent methyltransferase
M0696_12505	COG2010	Cytochrome c
M0696_12510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M0696_12515	COG0358	DNA primase activity
M0696_12520	COG1671	Belongs to the UPF0178 family
M0696_12525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
M0696_12530	COG0517	IMP dehydrogenase activity
M0696_12535	COG0751	glycine-tRNA ligase activity
M0696_12540	COG0752	glycyl-tRNA synthetase alpha subunit
M0696_12545	COG1381	Involved in DNA repair and RecF pathway recombination
M0696_12555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M0696_12560	COG0295	cytidine deaminase activity
M0696_12565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M0696_12570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
M0696_12575	COG1480	7TM receptor with intracellular HD hydrolase
M0696_12580	COG1702	phosphate starvation-inducible protein PhoH
M0696_12585	COG0561	phosphatase activity
M0696_12600	COG4864	UPF0365 protein
M0696_12605	COG1030	water channel activity
M0696_12610	COG1610	YqeY-like protein
M0696_12620	COG1283	sodium-dependent phosphate transmembrane transporter activity
M0696_12625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M0696_12630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M0696_12635	COG2264	protein methyltransferase activity
M0696_12640	COG0484	heat shock protein binding
M0696_12650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
M0696_12655	COG1420	regulation of RNA biosynthetic process
M0696_12660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M0696_12665	COG0481	GTPase activity
M0696_12675	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_12680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
M0696_12685	COG0268	Binds directly to 16S ribosomal RNA
M0696_12690	COG1466	dna polymerase III delta subunit
M0696_12705	COG0658	competence protein
M0696_12705	COG2333	competence protein COMEC
M0696_12710	COG2131	deaminase
M0696_12715	COG1596	polysaccharide export
M0696_12715	COG1555	photosystem II stabilization
M0696_12720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M0696_12725	COG2226	methyltransferase
M0696_12730	COG0799	negative regulation of ribosome biogenesis
M0696_12735	COG1713	HD superfamily hydrolase involved in NAD metabolism
M0696_12740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
M0696_12745	COG1534	Rna-binding protein
M0696_12750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M0696_12755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M0696_12760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M0696_12770	COG2755	lipolytic protein G-D-S-L family
M0696_12775	COG3409	Peptidoglycan-binding domain 1 protein
M0696_12775	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_12780	COG0398	Pfam SNARE associated Golgi protein
M0696_12785	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
M0696_12795	COG3209	COG3209 Rhs family protein
M0696_12805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M0696_12820	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_12830	COG1174	glycine betaine transport
M0696_12835	COG1125	glycine betaine transport
M0696_12835	COG0517	IMP dehydrogenase activity
M0696_12840	COG3321	synthase
M0696_12840	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_12840	COG0604	alcohol dehydrogenase
M0696_12845	COG1733	regulation of RNA biosynthetic process
M0696_12850	COG0457	Tetratricopeptide repeat
M0696_12860	COG5444	nuclease activity
M0696_12870	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_12870	COG3409	Peptidoglycan-binding domain 1 protein
M0696_12875	COG4824	toxin secretion phage lysis holin
M0696_12905	COG3778	Protein conserved in bacteria
M0696_12910	COG3299	homolog of phage Mu protein gp47
M0696_12915	COG3628	GPW Gp25 family protein
M0696_12925	COG4193	domain, Protein
M0696_12930	COG1652	LysM domain
M0696_12935	COG3953	SLT domain
M0696_12935	COG5280	Phage tail tape measure protein TP901
M0696_13000	COG4653	Phage capsid family
M0696_13005	COG0338	D12 class N6 adenine-specific DNA methyltransferase
M0696_13015	COG2369	cell adhesion
M0696_13020	COG5518	Phage portal protein
M0696_13025	COG1783	phage Terminase large subunit
M0696_13030	COG5484	DNA packaging
M0696_13055	COG3677	Transposase
M0696_13080	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
M0696_13090	COG1484	DNA-dependent DNA replication
M0696_13095	COG3935	DnaD domain protein
M0696_13100	COG3723	Recombinational DNA repair protein, rece pathway
M0696_13105	COG5377	YqaJ viral recombinase family
M0696_13140	COG3620	sequence-specific DNA binding
M0696_13155	COG2856	Zn peptidase
M0696_13175	COG2323	membrane
M0696_13180	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M0696_13185	COG0730	response to heat
M0696_13190	COG0425	Belongs to the sulfur carrier protein TusA family
M0696_13195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_13195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_13200	COG2210	Belongs to the sulfur carrier protein TusA family
M0696_13205	COG0425	Belongs to the sulfur carrier protein TusA family
M0696_13205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_13210	COG1054	Belongs to the UPF0176 family
M0696_13215	COG2210	Belongs to the sulfur carrier protein TusA family
M0696_13220	COG1937	Protein conserved in bacteria
M0696_13230	COG0662	Cupin 2, conserved barrel domain protein
M0696_13240	COG0604	alcohol dehydrogenase
M0696_13250	COG2315	Protein conserved in bacteria
M0696_13255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M0696_13270	COG0583	DNA-binding transcription factor activity
M0696_13275	COG0457	Tetratricopeptide repeat
M0696_13290	COG5444	nuclease activity
M0696_13300	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_13300	COG3409	Peptidoglycan-binding domain 1 protein
M0696_13305	COG4824	toxin secretion phage lysis holin
M0696_13330	COG2856	Zn peptidase
M0696_13345	COG0789	Transcriptional regulator
M0696_13345	COG4978	Transcriptional regulator
M0696_13350	COG2814	Major facilitator Superfamily
M0696_13355	COG0456	acetyltransferase
M0696_13360	COG1253	flavin adenine dinucleotide binding
M0696_13380	COG0789	Transcriptional regulator
M0696_13380	COG4978	Transcriptional regulator
M0696_13390	COG2315	Protein conserved in bacteria
M0696_13400	COG3443	Belongs to the bacterial solute-binding protein 9 family
M0696_13405	COG4991	sh3 domain protein
M0696_13410	COG4991	sh3 domain protein
M0696_13420	COG5577	PFAM Coat F domain
M0696_13425	COG1063	alcohol dehydrogenase
M0696_13435	COG5577	PFAM Coat F domain
M0696_13445	COG0789	Transcriptional regulator
M0696_13450	COG0789	Transcriptional regulator
M0696_13465	COG1064	alcohol dehydrogenase
M0696_13470	COG0693	protein deglycase activity
M0696_13475	COG1621	beta-fructofuranosidase activity
M0696_13485	COG3716	PTS system mannose fructose sorbose family IID component
M0696_13490	COG3715	PTS system
M0696_13495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_13500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_13505	COG3933	PFAM sigma-54 factor interaction domain-containing protein
M0696_13505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M0696_13525	COG1113	amino acid transport
M0696_13530	COG1280	lysine exporter protein (LysE YggA)
M0696_13535	COG1378	Sugar-specific transcriptional regulator TrmB
M0696_13540	COG1595	DNA-templated transcription, initiation
M0696_13550	COG2755	lipolytic protein G-D-S-L family
M0696_13550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
M0696_13560	COG2124	cytochrome p450
M0696_13560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M0696_13565	COG1309	transcriptional regulator
M0696_13570	COG2226	methyltransferase
M0696_13585	COG2116	formate transmembrane transporter activity
M0696_13590	COG5609	conserved protein (DUF2294)
M0696_13595	COG3383	formate dehydrogenase (NAD+) activity
M0696_13600	COG2427	Protein of unknown function (DUF1641)
M0696_13610	COG0626	cystathionine gamma-synthase activity
M0696_13615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M0696_13620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M0696_13625	COG2226	methyltransferase
M0696_13640	COG0768	penicillin binding
M0696_13645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M0696_13650	COG0572	uridine kinase
M0696_13655	COG0826	peptidase U32
M0696_13660	COG0826	peptidase U32
M0696_13665	COG4122	O-methyltransferase activity
M0696_13670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M0696_13675	COG3906	Belongs to the UPF0473 family
M0696_13680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M0696_13685	COG4472	Bacterial protein of unknown function (DUF965)
M0696_13690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M0696_13695	COG0628	permease
M0696_13710	COG3881	PFAM PRC-barrel domain
M0696_13715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M0696_13720	COG0457	Tetratricopeptide repeat
M0696_13725	COG0482	sulfurtransferase activity
M0696_13730	COG1104	cysteine desulfurase activity
M0696_13735	COG1959	2 iron, 2 sulfur cluster binding
M0696_13740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M0696_13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M0696_13755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
M0696_13760	COG0124	histidyl-tRNA synthetase
M0696_13770	COG3103	Sh3 type 3 domain protein
M0696_13770	COG4991	sh3 domain protein
M0696_13770	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_13775	COG1490	D-aminoacyl-tRNA deacylase activity
M0696_13780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M0696_13785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M0696_13790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M0696_13790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M0696_13795	COG5416	Lipopolysaccharide assembly protein A domain
M0696_13800	COG0490	domain, Protein
M0696_13805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M0696_13805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M0696_13815	COG2244	polysaccharide biosynthetic process
M0696_13820	COG2323	membrane
M0696_13830	COG1862	Preprotein translocase
M0696_13835	COG0343	queuine tRNA-ribosyltransferase activity
M0696_13840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
M0696_13850	COG2255	four-way junction helicase activity
M0696_13855	COG0632	four-way junction helicase activity
M0696_13865	COG2814	Major facilitator Superfamily
M0696_13870	COG0673	inositol 2-dehydrogenase activity
M0696_13875	COG2112	serine threonine protein kinase
M0696_13885	COG1115	amino acid carrier protein
M0696_13890	COG0217	transcriptional regulatory protein
M0696_13900	COG1388	LysM domain
M0696_13905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M0696_13910	COG0157	Belongs to the NadC ModD family
M0696_13915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M0696_13920	COG1104	cysteine desulfurase activity
M0696_13925	COG1827	regulation of RNA biosynthetic process
M0696_13930	COG0077	Prephenate dehydratase
M0696_13935	COG4492	Belongs to the UPF0735 family
M0696_13940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M0696_13945	COG3290	protein histidine kinase activity
M0696_13955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
M0696_13960	COG2868	ribosomal protein
M0696_13965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
M0696_13970	COG1994	Peptidase M50
M0696_13975	COG0739	heme binding
M0696_13980	COG2894	cell division
M0696_13985	COG0850	regulation of cytokinetic process
M0696_13990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M0696_14000	COG1077	Cell shape determining protein MreB Mrl
M0696_14005	COG2003	Belongs to the UPF0758 family
M0696_14010	COG0424	maF-like protein
M0696_14020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M0696_14025	COG0285	dihydrofolate synthase activity
M0696_14030	COG0525	valine-tRNA ligase activity
M0696_14040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_14045	COG1388	LysM domain
M0696_14050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
M0696_14055	COG0113	porphobilinogen synthase activity
M0696_14060	COG1587	Uroporphyrinogen-III synthase
M0696_14065	COG0181	hydroxymethylbilane synthase activity
M0696_14070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M0696_14075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
M0696_14085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
M0696_14090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M0696_14095	COG0470	DNA polymerase III
M0696_14095	COG1067	ATP-dependent peptidase activity
M0696_14100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
M0696_14105	COG0544	peptidyl-prolyl cis-trans isomerase activity
M0696_14110	COG0457	Tetratricopeptide repeat
M0696_14110	COG1477	protein flavinylation
M0696_14115	COG0066	3-isopropylmalate dehydratase activity
M0696_14120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M0696_14125	COG0473	3-isopropylmalate dehydrogenase activity
M0696_14130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M0696_14135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M0696_14140	COG0440	acetolactate synthase activity
M0696_14145	COG0028	Belongs to the TPP enzyme family
M0696_14155	COG0454	-acetyltransferase
M0696_14160	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
M0696_14170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M0696_14185	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
M0696_14200	COG0622	Phosphoesterase
M0696_14205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M0696_14210	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
M0696_14215	COG5401	PFAM Sporulation and spore germination
M0696_14220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M0696_14225	COG1846	Transcriptional regulator
M0696_14230	COG2197	response regulator
M0696_14235	COG0824	Thioesterase
M0696_14240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M0696_14245	COG1053	succinate dehydrogenase
M0696_14250	COG2009	succinate dehydrogenase
M0696_14255	COG1719	4-vinyl reductase, 4VR
M0696_14260	COG0527	aspartate kinase activity
M0696_14265	COG0322	excinuclease ABC activity
M0696_14270	COG3118	belongs to the thioredoxin family
M0696_14275	COG3534	alpha-L-arabinofuranosidase
M0696_14280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M0696_14285	COG2086	electron transfer activity
M0696_14290	COG1024	Enoyl-CoA hydratase
M0696_14295	COG1309	transcriptional regulator
M0696_14300	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_14305	COG3766	membrane
M0696_14310	COG1193	negative regulation of DNA recombination
M0696_14315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M0696_14315	COG1796	DNA polymerase
M0696_14320	COG1286	toxin biosynthetic process
M0696_14325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
M0696_14330	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M0696_14335	COG0072	phenylalanine-tRNA ligase activity
M0696_14335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_14340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M0696_14350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M0696_14360	COG3835	regulator
M0696_14365	COG0277	FAD linked oxidase domain protein
M0696_14370	COG0247	lactate metabolic process
M0696_14375	COG0346	lactoylglutathione lyase activity
M0696_14385	COG1966	Carbon starvation protein
M0696_14390	COG3534	alpha-L-arabinofuranosidase
M0696_14395	COG0395	ABC-type sugar transport system, permease component
M0696_14400	COG1175	transmembrane transport
M0696_14405	COG1653	transport
M0696_14410	COG0371	Dehydrogenase
M0696_14415	COG0647	UMP catabolic process
M0696_14420	COG0235	Class ii aldolase
M0696_14425	COG1069	ribulokinase activity
M0696_14430	COG2160	L-arabinose isomerase activity
M0696_14435	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_14440	COG1363	Peptidase, m42
M0696_14450	COG3326	Membrane
M0696_14455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
M0696_14460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
M0696_14465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
M0696_14475	COG1346	cytolysis
M0696_14480	COG1380	Effector of murein hydrolase LrgA
M0696_14485	COG3279	Response regulator of the LytR AlgR family
M0696_14490	COG3275	phosphorelay sensor kinase activity
M0696_14495	COG1011	Hydrolase
M0696_14500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M0696_14510	COG0398	Pfam SNARE associated Golgi protein
M0696_14515	COG1484	DNA-dependent DNA replication
M0696_14520	COG3611	Membrane attachment protein
M0696_14525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M0696_14530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M0696_14535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M0696_14540	COG1733	regulation of RNA biosynthetic process
M0696_14545	COG2814	Major facilitator Superfamily
M0696_14550	COG0656	L-ascorbic acid biosynthetic process
M0696_14555	COG0237	dephospho-CoA kinase activity
M0696_14560	COG1971	Probably functions as a manganese efflux pump
M0696_14565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
M0696_14570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M0696_14570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M0696_14575	COG5002	protein histidine kinase activity
M0696_14580	COG0745	RESPONSE REGULATOR receiver
M0696_14585	COG0039	L-malate dehydrogenase activity
M0696_14590	COG0538	isocitrate dehydrogenase activity
M0696_14595	COG0372	Belongs to the citrate synthase family
M0696_14600	COG2707	UPF0756 membrane protein
M0696_14605	COG0628	permease
M0696_14610	COG3030	protein affecting phage T7 exclusion by the F plasmid
M0696_14615	COG0469	pyruvate kinase activity
M0696_14620	COG0205	6-phosphofructokinase activity
M0696_14625	COG0825	malonyl-CoA metabolic process
M0696_14630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
M0696_14635	COG0281	malic enzyme
M0696_14640	COG0587	DNA-directed DNA polymerase activity
M0696_14660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M0696_14670	COG4109	DRTGG domain
M0696_14675	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M0696_14680	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_14685	COG0165	Argininosuccinate lyase
M0696_14690	COG0137	argininosuccinate synthase activity
M0696_14695	COG0521	Mo-molybdopterin cofactor biosynthetic process
M0696_14700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M0696_14705	COG0827	DNA restriction-modification system
M0696_14710	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M0696_14715	COG3874	Sporulation protein YtfJ
M0696_14725	COG1714	RDD family
M0696_14730	COG0616	signal peptide processing
M0696_14735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M0696_14740	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M0696_14745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M0696_14755	COG0301	tRNA thio-modification
M0696_14760	COG1104	cysteine desulfurase activity
M0696_14765	COG1114	Component of the transport system for branched-chain amino acids
M0696_14770	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
M0696_14775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M0696_14780	COG1309	transcriptional regulator
M0696_14785	COG1956	GAF domain-containing protein
M0696_14790	COG2199	diguanylate cyclase activity
M0696_14790	COG2203	Gaf domain
M0696_14795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M0696_14800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M0696_14805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M0696_14810	COG0454	-acetyltransferase
M0696_14815	COG0517	IMP dehydrogenase activity
M0696_14820	COG0123	including yeast histone deacetylase and acetoin utilization protein
M0696_14830	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M0696_14835	COG1609	Transcriptional regulator
M0696_14840	COG1605	Chorismate mutase
M0696_14840	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M0696_14845	COG3118	belongs to the thioredoxin family
M0696_14850	COG4980	gas vesicle protein
M0696_14855	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M0696_14860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M0696_14865	COG1674	ftsk spoiiie
M0696_14870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_14875	COG4848	Belongs to the UPF0354 family
M0696_14880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_14895	COG1363	Peptidase, m42
M0696_14900	COG5584	Small secreted protein
M0696_14905	COG0281	malic enzyme
M0696_14910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_14915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M0696_14925	COG0510	thiamine kinase activity
M0696_14930	COG1523	belongs to the glycosyl hydrolase 13 family
M0696_14935	COG1597	lipid kinase activity
M0696_14945	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M0696_14950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M0696_14955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_14960	COG2252	PERMEase
M0696_14965	COG4473	ABC transporter
M0696_14970	COG1131	(ABC) transporter
M0696_14975	COG1349	DNA-binding transcription factor activity
M0696_14980	COG1187	pseudouridine synthase activity
M0696_14985	COG2244	polysaccharide biosynthetic process
M0696_14990	COG2081	HI0933 family
M0696_14995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M0696_15005	COG5578	integral membrane protein
M0696_15010	COG0673	inositol 2-dehydrogenase activity
M0696_15015	COG1653	transport
M0696_15020	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
M0696_15025	COG4209	transmembrane transport
M0696_15030	COG2207	Transcriptional regulator
M0696_15035	COG1653	transport
M0696_15040	COG0395	ABC-type sugar transport system, permease component
M0696_15045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_15050	COG2124	cytochrome p450
M0696_15055	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
M0696_15065	COG0156	8-amino-7-oxononanoate synthase activity
M0696_15070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M0696_15085	COG1073	alpha beta
M0696_15090	COG1609	Transcriptional regulator
M0696_15095	COG1653	transport
M0696_15100	COG1175	transmembrane transport
M0696_15105	COG0395	ABC-type sugar transport system, permease component
M0696_15110	COG1486	melibiose metabolic process
M0696_15115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_15120	COG0495	leucyl-tRNA aminoacylation
M0696_15130	COG2202	Pas domain
M0696_15130	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_15135	COG2814	Major facilitator Superfamily
M0696_15140	COG2433	Pfam Transposase IS66
M0696_15145	COG0577	efflux transmembrane transporter activity
M0696_15150	COG1136	(ABC) transporter
M0696_15155	COG2205	protein histidine kinase activity
M0696_15160	COG0745	RESPONSE REGULATOR receiver
M0696_15165	COG0577	efflux transmembrane transporter activity
M0696_15170	COG1136	(ABC) transporter
M0696_15185	COG1131	(ABC) transporter
M0696_15190	COG1725	Transcriptional regulator
M0696_15205	COG1242	4 iron, 4 sulfur cluster binding
M0696_15210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M0696_15220	COG2267	carboxylic ester hydrolase activity
M0696_15225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M0696_15230	COG1113	amino acid transport
M0696_15235	COG0367	asparagine synthase
M0696_15240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
M0696_15245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
M0696_15255	COG1506	peptidase
M0696_15260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M0696_15265	COG1116	anion transmembrane transporter activity
M0696_15270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M0696_15275	COG0494	nUDIX hydrolase
M0696_15280	COG4824	toxin secretion phage lysis holin
M0696_15285	COG0783	Belongs to the Dps family
M0696_15300	COG1854	S-ribosylhomocysteine lyase activity
M0696_15305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
M0696_15310	COG0288	reversible hydration of carbon dioxide
M0696_15315	COG0254	rRNA binding
M0696_15320	COG1271	oxidase subunit
M0696_15325	COG1294	oxidase, subunit
M0696_15335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M0696_15340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M0696_15340	COG1321	iron dependent repressor
M0696_15345	COG1121	(ABC) transporter
M0696_15350	COG0803	Belongs to the bacterial solute-binding protein 9 family
M0696_15355	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_15360	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_15365	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M0696_15370	COG0596	Alpha beta hydrolase
M0696_15375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
M0696_15380	COG1169	isochorismate synthase
M0696_15385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M0696_15390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M0696_15395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M0696_15400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_15405	COG0438	transferase activity, transferring glycosyl groups
M0696_15415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_15420	COG0438	transferase activity, transferring glycosyl groups
M0696_15425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_15430	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
M0696_15435	COG0058	SHG alpha-glucan phosphorylase activity
M0696_15445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M0696_15450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M0696_15455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
M0696_15580	COG3859	Proton-coupled thiamine transporter YuaJ
M0696_15585	COG1247	-acetyltransferase
M0696_15590	COG2268	Band 7 protein
M0696_15595	COG1585	Membrane protein implicated in regulation of membrane protease activity
M0696_15600	COG2318	DinB family
M0696_15610	COG1454	alcohol dehydrogenase
M0696_15615	COG1012	belongs to the aldehyde dehydrogenase family
M0696_15620	COG1510	regulation of RNA biosynthetic process
M0696_15630	COG0569	domain protein
M0696_15635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M0696_15640	COG4682	membrane
M0696_15645	COG1705	Flagellar rod assembly protein muramidase FlgJ
M0696_15650	COG0477	Major facilitator Superfamily
M0696_15655	COG5553	Cysteine dioxygenase type I
M0696_15665	COG1968	undecaprenyl-diphosphatase activity
M0696_15670	COG0628	permease
M0696_15675	COG0673	inositol 2-dehydrogenase activity
M0696_15680	COG4806	L-rhamnose isomerase
M0696_15685	COG3254	rhamnose metabolic process
M0696_15690	COG1070	Carbohydrate kinase
M0696_15695	COG1349	DNA-binding transcription factor activity
M0696_15700	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_15700	COG3347	Dehydrogenase
M0696_15705	COG0840	transmembrane signaling receptor activity
M0696_15710	COG0840	transmembrane signaling receptor activity
M0696_15715	COG0840	transmembrane signaling receptor activity
M0696_15720	COG0840	transmembrane signaling receptor activity
M0696_15735	COG2070	2-Nitropropane dioxygenase
M0696_15740	COG0432	Pfam Uncharacterised protein family UPF0047
M0696_15745	COG0366	Alpha amylase catalytic
M0696_15750	COG1253	flavin adenine dinucleotide binding
M0696_15755	COG2738	Putative neutral zinc metallopeptidase
M0696_15770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M0696_15785	COG0166	Belongs to the GPI family
M0696_15790	COG1979	alcohol dehydrogenase
M0696_15795	COG1979	alcohol dehydrogenase
M0696_15800	COG2155	Conserved Protein
M0696_15805	COG1098	S1 RNA binding domain
M0696_15810	COG0436	Aminotransferase
M0696_15815	COG1522	sequence-specific DNA binding
M0696_15820	COG2267	carboxylic ester hydrolase activity
M0696_15830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M0696_15835	COG2205	protein histidine kinase activity
M0696_15845	COG5018	Exonuclease
M0696_15855	COG2814	Major facilitator Superfamily
M0696_15860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_15865	COG3011	Protein conserved in bacteria
M0696_15875	COG3290	protein histidine kinase activity
M0696_15880	COG4565	transcriptional regulatory protein
M0696_15885	COG1744	ABC transporter substrate-binding protein PnrA-like
M0696_15890	COG3845	ABC transporter
M0696_15895	COG4603	Belongs to the binding-protein-dependent transport system permease family
M0696_15900	COG1079	Belongs to the binding-protein-dependent transport system permease family
M0696_15905	COG3493	citrate carrier protein
M0696_15915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M0696_15915	COG2111	Na H antiporter
M0696_15920	COG2111	Na H antiporter
M0696_15925	COG1006	Multisubunit Na H antiporter MnhC subunit
M0696_15930	COG0651	ATP synthesis coupled electron transport
M0696_15935	COG1863	multisubunit Na H antiporter MnhE subunit
M0696_15940	COG2212	antiporter activity
M0696_15945	COG1320	monovalent cation:proton antiporter activity
M0696_15950	COG2050	protein possibly involved in aromatic compounds catabolism
M0696_15955	COG2197	response regulator
M0696_15970	COG0142	geranyltranstransferase activity
M0696_15990	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
M0696_15995	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M0696_16000	COG1335	isochorismatase
M0696_16005	COG5506	Protein of unknown function (DUF1694)
M0696_16020	COG0628	permease
M0696_16030	COG1418	mRNA catabolic process
M0696_16035	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_16045	COG1511	domain protein
M0696_16050	COG0433	COG0433 Predicted ATPase
M0696_16050	COG1674	ftsk spoiiie
M0696_16055	COG4499	WXG100 protein secretion system (Wss), protein YukC
M0696_16060	COG5417	Belongs to the EsaB family
M0696_16065	COG4842	Belongs to the WXG100 family
M0696_16070	COG2508	Transcriptional regulator
M0696_16070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M0696_16075	COG0686	Belongs to the AlaDH PNT family
M0696_16080	COG5634	Uncharacterized conserved protein (DUF2278)
M0696_16085	COG3251	PFAM MbtH domain protein
M0696_16090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_16095	COG1535	isochorismatase
M0696_16095	COG3433	isochorismatase activity
M0696_16100	COG1021	2,3-dihydroxybenzoate-AMP ligase
M0696_16105	COG1169	isochorismate synthase
M0696_16110	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_16115	COG2819	hydrolase of the alpha beta superfamily
M0696_16120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M0696_16125	COG1268	BioY protein
M0696_16130	COG2056	Na+-H+ antiporter family
M0696_16135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
M0696_16140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M0696_16145	COG3584	3D domain protein
M0696_16160	COG1252	NADH dehydrogenase
M0696_16165	COG0492	ferredoxin-NADP+ reductase activity
M0696_16175	COG0516	GMP reductase activity
M0696_16180	COG0316	Belongs to the HesB IscA family
M0696_16185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
M0696_16190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M0696_16195	COG4844	belongs to the
M0696_16200	COG1252	NADH dehydrogenase
M0696_16205	COG4837	Protein of unknown function (DUF1462)
M0696_16210	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M0696_16220	COG0083	homoserine kinase activity
M0696_16225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M0696_16230	COG0460	homoserine dehydrogenase
M0696_16235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_16240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M0696_16245	COG0647	UMP catabolic process
M0696_16250	COG2445	Protein of unknown function DUF86
M0696_16255	COG4470	Protein conserved in bacteria
M0696_16265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M0696_16270	COG0739	heme binding
M0696_16280	COG3377	Domain of unknown function (DUF1805)
M0696_16285	COG0737	Belongs to the 5'-nucleotidase family
M0696_16290	COG0730	response to heat
M0696_16295	COG1801	Protein of unknown function DUF72
M0696_16305	COG1819	glycosyl
M0696_16310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M0696_16315	COG2508	Transcriptional regulator
M0696_16320	COG2233	PERMEase
M0696_16325	COG2233	PERMEase
M0696_16330	COG3195	allantoin biosynthetic process
M0696_16330	COG3648	Uricase
M0696_16335	COG2351	hydroxyisourate hydrolase activity
M0696_16350	COG2080	2 iron, 2 sulfur cluster binding
M0696_16355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M0696_16360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
M0696_16365	COG2068	MobA-Related Protein
M0696_16370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
M0696_16375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M0696_16380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_16390	COG2356	endonuclease I
M0696_16395	COG3842	ATPase activity
M0696_16400	COG2188	Transcriptional regulator
M0696_16405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_16410	COG0395	ABC-type sugar transport system, permease component
M0696_16415	COG1175	transmembrane transport
M0696_16420	COG1653	transport
M0696_16425	COG2222	sugar isomerase
M0696_16430	COG0322	excinuclease ABC activity
M0696_16435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_16450	COG0719	Fe-S assembly protein
M0696_16455	COG0822	iron-sulfur transferase activity
M0696_16460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M0696_16465	COG0719	Fe-S assembly protein
M0696_16470	COG0396	ATPase activity
M0696_16480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M0696_16485	COG1464	Belongs to the NlpA lipoprotein family
M0696_16490	COG2011	ABC-type metal ion transport system permease component
M0696_16495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M0696_16505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_16510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M0696_16520	COG0509	glycine decarboxylation via glycine cleavage system
M0696_16525	COG1393	Belongs to the ArsC family
M0696_16530	COG1960	acyl-CoA dehydrogenase activity
M0696_16535	COG0183	Belongs to the thiolase family
M0696_16540	COG1024	Enoyl-CoA hydratase
M0696_16540	COG1250	3-hydroxyacyl-CoA dehydrogenase
M0696_16550	COG0506	proline dehydrogenase activity
M0696_16560	COG5577	PFAM Coat F domain
M0696_16565	COG1846	Transcriptional regulator
M0696_16570	COG0477	Major facilitator Superfamily
M0696_16575	COG1942	4-Oxalocrotonate Tautomerase
M0696_16580	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_16585	COG0583	DNA-binding transcription factor activity
M0696_16595	COG1120	ATPase activity
M0696_16610	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_16615	COG0783	Belongs to the Dps family
M0696_16620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_16625	COG0745	RESPONSE REGULATOR receiver
M0696_16630	COG2770	Histidine kinase
M0696_16630	COG2205	protein histidine kinase activity
M0696_16640	COG1309	transcriptional regulator
M0696_16645	COG0114	fumarate hydratase activity
M0696_16655	COG0697	spore germination
M0696_16660	COG0814	amino acid
M0696_16670	COG2197	response regulator
M0696_16675	COG4585	Histidine kinase
M0696_16680	COG4758	membrane
M0696_16685	COG3595	metallopeptidase activity
M0696_16690	COG1842	Phage shock protein A
M0696_16695	COG4758	membrane
M0696_16700	COG2814	Major facilitator Superfamily
M0696_16705	COG2096	Adenosyltransferase
M0696_16710	COG1120	ATPase activity
M0696_16715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_16720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_16725	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_16730	COG3386	PFAM SMP-30 Gluconolaconase
M0696_16735	COG2205	protein histidine kinase activity
M0696_16740	COG0745	RESPONSE REGULATOR receiver
M0696_16750	COG1191	sigma factor activity
M0696_16760	COG2140	Oxalate decarboxylase
M0696_16770	COG0577	efflux transmembrane transporter activity
M0696_16775	COG1136	(ABC) transporter
M0696_16780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M0696_16785	COG1120	ATPase activity
M0696_16790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_16795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_16800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_16805	COG0531	amino acid
M0696_16815	COG1988	membrane-bound metal-dependent
M0696_16820	COG1368	sulfuric ester hydrolase activity
M0696_16825	COG1910	domain protein
M0696_16830	COG0725	ABC transporter, periplasmic molybdate-binding protein
M0696_16835	COG4149	molybdate abc transporter
M0696_16840	COG0656	L-ascorbic acid biosynthetic process
M0696_16850	COG0025	NhaP-type Na H and K H
M0696_16855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M0696_16860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M0696_16865	COG3973	AAA domain
M0696_16870	COG2860	membrane
M0696_16875	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M0696_16880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M0696_16885	COG2217	Heavy metal translocating P-type atpase
M0696_16890	COG2217	Heavy metal translocating P-type atpase
M0696_16895	COG2608	mercury ion transmembrane transporter activity
M0696_16900	COG1937	Protein conserved in bacteria
M0696_16905	COG0673	inositol 2-dehydrogenase activity
M0696_16910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M0696_16915	COG1289	transmembrane transporter activity
M0696_16920	COG1802	Transcriptional regulator
M0696_16925	COG0697	spore germination
M0696_16935	COG2076	Multidrug Resistance protein
M0696_16940	COG1309	transcriptional regulator
M0696_16945	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_16955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
M0696_16960	COG0557	exoribonuclease II activity
M0696_16965	COG1647	Serine aminopeptidase, S33
M0696_16970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M0696_16975	COG0596	Alpha beta hydrolase
M0696_16980	COG1476	TRANSCRIPTIONal
M0696_16985	COG1396	sequence-specific DNA binding
M0696_16990	COG1396	sequence-specific DNA binding
M0696_16995	COG1733	regulation of RNA biosynthetic process
M0696_17000	COG0840	transmembrane signaling receptor activity
M0696_17005	COG1174	glycine betaine transport
M0696_17010	COG1732	Glycine betaine
M0696_17015	COG1174	glycine betaine transport
M0696_17020	COG0517	IMP dehydrogenase activity
M0696_17020	COG1125	glycine betaine transport
M0696_17025	COG1510	regulation of RNA biosynthetic process
M0696_17030	COG1174	glycine betaine transport
M0696_17035	COG1732	Glycine betaine
M0696_17040	COG1174	glycine betaine transport
M0696_17045	COG1125	glycine betaine transport
M0696_17045	COG0517	IMP dehydrogenase activity
M0696_17050	COG1510	regulation of RNA biosynthetic process
M0696_17060	COG3064	Membrane
M0696_17065	COG4640	response to antibiotic
M0696_17070	COG0456	acetyltransferase
M0696_17080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M0696_17085	COG0149	triose-phosphate isomerase activity
M0696_17090	COG0126	phosphoglycerate kinase activity
M0696_17095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M0696_17100	COG2390	Transcriptional regulator
M0696_17105	COG2814	Major facilitator Superfamily
M0696_17110	COG1609	Transcriptional regulator
M0696_17115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_17120	COG0583	DNA-binding transcription factor activity
M0696_17125	COG0697	spore germination
M0696_17130	COG1113	amino acid transport
M0696_17135	COG3858	chitin binding
M0696_17140	COG1556	Lactate utilization protein
M0696_17145	COG1139	Iron-sulfur cluster binding protein
M0696_17150	COG0247	lactate metabolic process
M0696_17165	COG2197	response regulator
M0696_17170	COG4585	Histidine kinase
M0696_17175	COG0842	Transport permease protein
M0696_17180	COG1131	(ABC) transporter
M0696_17185	COG0596	Alpha beta hydrolase
M0696_17190	COG2208	phosphoserine phosphatase activity
M0696_17195	COG3867	Arabinogalactan endo-beta-1,4-galactanase
M0696_17200	COG1874	Beta-galactosidase
M0696_17205	COG3833	ABC-type maltose transport systems, permease component
M0696_17210	COG1175	transmembrane transport
M0696_17215	COG2182	Extracellular solute-binding protein
M0696_17220	COG1609	Transcriptional regulator
M0696_17225	COG2186	Transcriptional regulator
M0696_17230	COG1620	l-lactate permease
M0696_17235	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M0696_17245	COG5039	Polysaccharide pyruvyl transferase
M0696_17250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M0696_17255	COG0110	maltose O-acetyltransferase activity
M0696_17260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M0696_17265	COG2244	polysaccharide biosynthetic process
M0696_17270	COG1216	Glycosyl transferase, family 2
M0696_17275	COG5039	Polysaccharide pyruvyl transferase
M0696_17280	COG1216	Glycosyl transferase, family 2
M0696_17290	COG0438	transferase activity, transferring glycosyl groups
M0696_17295	COG1215	transferase activity, transferring glycosyl groups
M0696_17300	COG0438	transferase activity, transferring glycosyl groups
M0696_17305	COG1086	Polysaccharide biosynthesis protein
M0696_17310	COG0489	protein tyrosine kinase activity
M0696_17315	COG3944	biosynthesis protein
M0696_17320	COG1396	sequence-specific DNA binding
M0696_17325	COG2272	Belongs to the type-B carboxylesterase lipase family
M0696_17335	COG3479	Phenolic acid decarboxylase
M0696_17345	COG1794	racemase activity, acting on amino acids and derivatives
M0696_17350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_17355	COG0473	3-isopropylmalate dehydrogenase activity
M0696_17360	COG1621	beta-fructofuranosidase activity
M0696_17365	COG1621	beta-fructofuranosidase activity
M0696_17370	COG0577	efflux transmembrane transporter activity
M0696_17375	COG1136	(ABC) transporter
M0696_17375	COG0577	efflux transmembrane transporter activity
M0696_17415	COG1132	(ABC) transporter
M0696_17445	COG3290	protein histidine kinase activity
M0696_17450	COG3279	Response regulator of the LytR AlgR family
M0696_17455	COG0531	amino acid
M0696_17460	COG1309	transcriptional regulator
M0696_17465	COG2076	Multidrug Resistance protein
M0696_17470	COG2076	Multidrug Resistance protein
M0696_17490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M0696_17495	COG0366	Alpha amylase catalytic
M0696_17500	COG1554	hydrolase, family 65, central catalytic
M0696_17505	COG5521	maltodextrose utilization protein MalA
M0696_17510	COG3833	ABC-type maltose transport systems, permease component
M0696_17515	COG1175	transmembrane transport
M0696_17520	COG2182	Extracellular solute-binding protein
M0696_17525	COG0366	Alpha amylase catalytic
M0696_17530	COG1609	Transcriptional regulator
M0696_17535	COG1611	Belongs to the LOG family
M0696_17540	COG1694	Mazg nucleotide pyrophosphohydrolase
M0696_17545	COG0659	secondary active sulfate transmembrane transporter activity
M0696_17550	COG0288	reversible hydration of carbon dioxide
M0696_17555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M0696_17560	COG0577	efflux transmembrane transporter activity
M0696_17565	COG1136	(ABC) transporter
M0696_17570	COG5002	protein histidine kinase activity
M0696_17575	COG0745	RESPONSE REGULATOR receiver
M0696_17585	COG2162	N-hydroxyarylamine O-acetyltransferase activity
M0696_17590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_17595	COG1481	regulation of sporulation
M0696_17600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M0696_17605	COG1660	Displays ATPase and GTPase activities
M0696_17610	COG1051	belongs to the nudix hydrolase family
M0696_17615	COG0492	ferredoxin-NADP+ reductase activity
M0696_17620	COG3883	PFAM NLP P60 protein
M0696_17620	COG0791	NLP P60 protein
M0696_17625	COG0457	Tetratricopeptide repeat
M0696_17630	COG1132	(ABC) transporter
M0696_17650	COG0140	phosphoribosyl-ATP diphosphatase activity
M0696_17650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M0696_17655	COG0107	imidazoleglycerol-phosphate synthase activity
M0696_17660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
M0696_17665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M0696_17670	COG0131	Imidazoleglycerol-phosphate dehydratase
M0696_17675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M0696_17680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M0696_17685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
M0696_17690	COG4990	cell redox homeostasis
M0696_17695	COG5297	Belongs to the glycosyl hydrolase family 6
M0696_17700	COG0110	maltose O-acetyltransferase activity
M0696_17705	COG0546	phosphoglycolate phosphatase activity
M0696_17710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M0696_17715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
M0696_17720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
M0696_17725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M0696_17730	COG0363	glucosamine-6-phosphate deaminase activity
M0696_17735	COG2188	Transcriptional regulator
M0696_17740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M0696_17745	COG1846	Transcriptional regulator
M0696_17750	COG2124	cytochrome p450
M0696_17760	COG1846	Transcriptional regulator
M0696_17765	COG2814	Major facilitator Superfamily
M0696_17770	COG1950	PFAM Membrane protein of
M0696_17775	COG1983	PspC domain protein
M0696_17780	COG3595	metallopeptidase activity
M0696_17795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M0696_17800	COG0556	nucleotide-excision repair
M0696_17805	COG4897	Protein conserved in bacteria
M0696_17810	COG0574	Belongs to the PEP-utilizing enzyme family
M0696_17810	COG3848	Pyruvate phosphate dikinase
M0696_17815	COG1309	transcriptional regulator
M0696_17820	COG2814	Major facilitator Superfamily
M0696_17825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_17835	COG0793	Belongs to the peptidase S41A family
M0696_17835	COG3409	Peptidoglycan-binding domain 1 protein
M0696_17840	COG2177	Part of the ABC transporter FtsEX involved in
M0696_17845	COG2884	Cell division ATP-binding protein ftsE
M0696_17850	COG2010	Cytochrome c
M0696_17855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_17865	COG0653	protein targeting
M0696_17870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M0696_17885	COG1516	flagellar protein fliS
M0696_17890	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M0696_17895	COG1334	flagellar protein FlaG
M0696_17900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M0696_17905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
M0696_17910	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
M0696_17920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M0696_17925	COG4786	Flagellar basal body rod
M0696_17925	COG1256	bacterial-type flagellum assembly
M0696_17930	COG3418	PFAM FlgN family protein
M0696_17935	COG2747	anti-sigma28 factor FlgM
M0696_17945	COG1040	competence protein
M0696_17955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M0696_17960	COG1307	EDD domain protein, DegV family
M0696_17965	COG2197	response regulator
M0696_17970	COG4585	Histidine kinase
M0696_17975	COG1739	Uncharacterized protein family UPF0029
M0696_17980	COG1316	TRANSCRIPTIONal
M0696_17985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M0696_17990	COG0438	transferase activity, transferring glycosyl groups
M0696_17995	COG1215	transferase activity, transferring glycosyl groups
M0696_18000	COG3206	protein involved in exopolysaccharide biosynthesis
M0696_18005	COG3307	-O-antigen
M0696_18010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M0696_18015	COG0438	transferase activity, transferring glycosyl groups
M0696_18015	COG0297	glycogen (starch) synthase activity
M0696_18020	COG2244	polysaccharide biosynthetic process
M0696_18035	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_18035	COG2247	cell wall binding repeat
M0696_18040	COG2247	cell wall binding repeat
M0696_18040	COG2385	sporulation resulting in formation of a cellular spore
M0696_18050	COG1316	TRANSCRIPTIONal
M0696_18055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M0696_18075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M0696_18080	COG1134	teichoic acid transport
M0696_18085	COG1682	transport, permease protein
M0696_18100	COG1215	transferase activity, transferring glycosyl groups
M0696_18100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M0696_18105	COG0463	Glycosyl transferase, family 2
M0696_18150	COG4193	domain, Protein
M0696_18155	COG1482	cell wall glycoprotein biosynthetic process
M0696_18160	COG0697	spore germination
M0696_18165	COG0814	amino acid
M0696_18175	COG2814	Major facilitator Superfamily
M0696_18180	COG1316	TRANSCRIPTIONal
M0696_18185	COG0561	phosphatase activity
M0696_18190	COG0791	NLP P60 protein
M0696_18200	COG2843	Capsule synthesis protein
M0696_18210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M0696_18215	COG1609	Transcriptional regulator
M0696_18220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_18225	COG1869	D-ribose catabolic process
M0696_18230	COG1129	ABC transporter
M0696_18235	COG1172	Belongs to the binding-protein-dependent transport system permease family
M0696_18240	COG1879	ABC-type sugar transport system periplasmic component
M0696_18245	COG3103	Sh3 type 3 domain protein
M0696_18255	COG2249	NAD(P)H dehydrogenase (quinone) activity
M0696_18260	COG3527	Alpha-acetolactate decarboxylase
M0696_18265	COG0028	Belongs to the TPP enzyme family
M0696_18270	COG0583	DNA-binding transcription factor activity
M0696_18275	COG5337	Spore coat protein CotH
M0696_18285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M0696_18295	COG0405	Gamma-glutamyltransferase
M0696_18300	COG1522	sequence-specific DNA binding
M0696_18305	COG2059	Chromate
M0696_18310	COG2059	Chromate
M0696_18320	COG0655	NAD(P)H dehydrogenase (quinone) activity
M0696_18325	COG0583	DNA-binding transcription factor activity
M0696_18335	COG2207	Transcriptional regulator
M0696_18335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_18360	COG5444	nuclease activity
M0696_18375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M0696_18380	COG4464	protein tyrosine phosphatase activity
M0696_18385	COG0489	protein tyrosine kinase activity
M0696_18390	COG3944	biosynthesis protein
M0696_18400	COG4715	Zinc finger, swim domain protein
M0696_18405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M0696_18410	COG0561	phosphatase activity
M0696_18415	COG1349	DNA-binding transcription factor activity
M0696_18420	COG0629	single-stranded DNA binding
M0696_18435	COG3764	Sortase (surface protein transpeptidase)
M0696_18445	COG3279	Response regulator of the LytR AlgR family
M0696_18455	COG0745	RESPONSE REGULATOR receiver
M0696_18455	COG2972	Histidine kinase
M0696_18460	COG1970	mechanosensitive ion channel activity
M0696_18465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M0696_18470	COG0457	Tetratricopeptide repeat
M0696_18475	COG4786	Flagellar basal body rod
M0696_18480	COG4786	Flagellar basal body rod
M0696_18485	COG1077	Cell shape determining protein MreB Mrl
M0696_18490	COG1609	Transcriptional regulator
M0696_18500	COG1846	Transcriptional regulator
M0696_18505	COG2814	Major facilitator Superfamily
M0696_18510	COG3420	alginic acid biosynthetic process
M0696_18515	COG1953	Uracil, thiamine, allantoin
M0696_18520	COG0477	Major facilitator Superfamily
M0696_18535	COG0004	ammonium transporteR
M0696_18540	COG0347	Belongs to the P(II) protein family
M0696_18545	COG0671	phosphoesterase, PA-phosphatase related
M0696_18555	COG0739	heme binding
M0696_18560	COG1247	-acetyltransferase
M0696_18570	COG2089	acid synthase
M0696_18580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M0696_18585	COG0789	Transcriptional regulator
M0696_18595	COG2910	NAD(P)H-binding
M0696_18600	COG1959	2 iron, 2 sulfur cluster binding
M0696_18605	COG0804	urea catabolic process
M0696_18610	COG0832	Belongs to the urease beta subunit family
M0696_18615	COG0831	urea catabolic process
M0696_18645	COG3237	CsbD-like
M0696_18650	COG1994	Peptidase M50
M0696_18655	COG0457	Tetratricopeptide repeat
M0696_18660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M0696_18665	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M0696_18675	COG2304	oxidoreductase activity
M0696_18680	COG2304	oxidoreductase activity
M0696_18685	COG2385	sporulation resulting in formation of a cellular spore
M0696_18690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M0696_18700	COG4836	Membrane
M0696_18715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
M0696_18720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
M0696_18725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
M0696_18730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M0696_18735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
M0696_18745	COG0356	it plays a direct role in the translocation of protons across the membrane
M0696_18755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
M0696_18760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
M0696_18765	COG4475	Protein of unknown function (DUF436)
M0696_18770	COG0698	ribose 5-phosphate isomerase
M0696_18775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M0696_18780	COG1971	Probably functions as a manganese efflux pump
M0696_18785	COG0009	L-threonylcarbamoyladenylate synthase
M0696_18790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M0696_18810	COG2890	protein-(glutamine-N5) methyltransferase activity
M0696_18815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
M0696_18820	COG0346	lactoylglutathione lyase activity
M0696_18825	COG0789	Transcriptional regulator
M0696_18830	COG0679	Auxin Efflux Carrier
M0696_18835	COG0281	malic enzyme
M0696_18840	COG1435	thymidine kinase activity
M0696_18850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M0696_18860	COG1494	fructose-1,6-bisphosphatase
M0696_18865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M0696_18870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M0696_18875	COG0191	fructose-bisphosphate aldolase activity
M0696_18880	COG2204	response regulator
M0696_18885	COG4821	SIS domain
M0696_18890	COG0504	CTP synthase activity
M0696_18895	COG3343	RNA polymerase activity
M0696_18900	COG1960	acyl-CoA dehydrogenase activity
M0696_18905	COG2181	nitrate reductase activity
M0696_18905	COG0247	lactate metabolic process
M0696_18910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M0696_18915	COG4294	response to UV
M0696_18925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M0696_18930	COG1132	(ABC) transporter
M0696_18935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M0696_18945	COG2181	nitrate reductase activity
M0696_18950	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M0696_18955	COG1140	nitrate reductase beta subunit
M0696_18960	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M0696_18965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M0696_18975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M0696_18980	COG2223	nitrite transmembrane transporter activity
M0696_18985	COG0018	arginyl-trna synthetase
M0696_18990	COG4506	Protein conserved in bacteria
M0696_19000	COG0535	radical SAM domain protein
M0696_19010	COG1131	(ABC) transporter
M0696_19035	COG3391	amine dehydrogenase activity
M0696_19040	COG3391	amine dehydrogenase activity
M0696_19045	COG0457	Tetratricopeptide repeat
M0696_19060	COG0010	Belongs to the arginase family
M0696_19065	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M0696_19070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_19080	COG1994	Peptidase M50
M0696_19085	COG1942	4-Oxalocrotonate Tautomerase
M0696_19090	COG1846	Transcriptional regulator
M0696_19095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M0696_19105	COG3465	dGTPase activity
M0696_19110	COG1078	dGTPase activity
M0696_19115	COG4844	belongs to the
M0696_19125	COG0697	spore germination
M0696_19130	COG0095	Lipoate-protein ligase
M0696_19135	COG0583	DNA-binding transcription factor activity
M0696_19140	COG0280	phosphate acetyltransferase
M0696_19145	COG3253	May function as heme-dependent peroxidase
M0696_19150	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_19155	COG0436	Aminotransferase
M0696_19160	COG2814	Major facilitator Superfamily
M0696_19165	COG0151	Belongs to the GarS family
M0696_19170	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_19175	COG1917	Cupin 2, conserved barrel domain protein
M0696_19180	COG0077	Prephenate dehydratase
M0696_19185	COG2814	Major facilitator Superfamily
M0696_19190	COG1012	belongs to the aldehyde dehydrogenase family
M0696_19195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M0696_19205	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
M0696_19210	COG1091	dTDP-4-dehydrorhamnose reductase activity
M0696_19215	COG1088	dTDP-glucose 4,6-dehydratase activity
M0696_19220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M0696_19225	COG3980	spore coat polysaccharide biosynthesis protein
M0696_19230	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
M0696_19235	COG2089	acid synthase
M0696_19240	COG0456	acetyltransferase
M0696_19245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M0696_19250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M0696_19255	COG0463	Glycosyl transferase, family 2
M0696_19265	COG2363	Small membrane protein
M0696_19270	COG2233	PERMEase
M0696_19280	COG1012	belongs to the aldehyde dehydrogenase family
M0696_19285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
M0696_19290	COG1216	Glycosyl transferase, family 2
M0696_19300	COG0351	phosphomethylpyrimidine kinase
M0696_19310	COG1621	beta-fructofuranosidase activity
M0696_19315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_19315	COG1263	PTS System
M0696_19320	COG2116	formate transmembrane transporter activity
M0696_19325	COG3711	transcriptional antiterminator
M0696_19335	COG1404	Belongs to the peptidase S8 family
M0696_19340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_19345	COG0778	Nitroreductase
M0696_19350	COG0772	Belongs to the SEDS family
M0696_19360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M0696_19365	COG1845	cytochrome c oxidase, subunit III
M0696_19380	COG2261	transglycosylase associated protein
M0696_19385	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M0696_19390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
M0696_19395	COG2246	polysaccharide biosynthetic process
M0696_19400	COG1309	transcriptional regulator
M0696_19410	COG3162	membrane
M0696_19415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_19420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M0696_19425	COG2837	iron assimilation
M0696_19430	COG2822	iron ion transport
M0696_19435	COG0672	)-iron permease
M0696_19440	COG0352	thiamine-phosphate diphosphorylase activity
M0696_19445	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
M0696_19450	COG0583	DNA-binding transcription factor activity
M0696_19455	COG1380	Effector of murein hydrolase LrgA
M0696_19460	COG1346	cytolysis
M0696_19465	COG2814	Major facilitator Superfamily
M0696_19470	COG4895	conserved protein (DUF2196)
M0696_19475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M0696_19480	COG0346	lactoylglutathione lyase activity
M0696_19490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_19495	COG1404	Belongs to the peptidase S8 family
M0696_19500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_19500	COG1263	PTS System
M0696_19505	COG3711	transcriptional antiterminator
M0696_19510	COG1442	glycosyl transferase family 8
M0696_19515	COG5522	Integral membrane protein (intg_mem_TP0381)
M0696_19520	COG1846	Transcriptional regulator
M0696_19525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M0696_19530	COG2234	aminopeptidase activity
M0696_19535	COG2357	RelA SpoT domain protein
M0696_19540	COG1575	Belongs to the MenA family. Type 1 subfamily
M0696_19555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_19560	COG1696	Membrane protein involved in D-alanine export
M0696_19565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_19570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M0696_19575	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
M0696_19580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_19615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M0696_19620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M0696_19645	COG1486	melibiose metabolic process
M0696_19650	COG1447	Phosphotransferase system cellobiose-specific component IIA
M0696_19655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_19660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_19665	COG3711	transcriptional antiterminator
M0696_19665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_19675	COG2094	Belongs to the DNA glycosylase MPG family
M0696_19680	COG0753	catalase activity
M0696_19685	COG2814	Major facilitator Superfamily
M0696_19690	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M0696_19695	COG1131	(ABC) transporter
M0696_19715	COG1595	DNA-templated transcription, initiation
M0696_19720	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M0696_19725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M0696_19730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M0696_19735	COG4988	ABC transporter
M0696_19740	COG1294	oxidase, subunit
M0696_19745	COG1271	oxidase subunit
M0696_19750	COG3493	citrate carrier protein
M0696_19755	COG0501	Belongs to the peptidase M48B family
M0696_19765	COG0726	polysaccharide deacetylase
M0696_19780	COG3842	ATPase activity
M0696_19785	COG2508	Transcriptional regulator
M0696_19790	COG1012	belongs to the aldehyde dehydrogenase family
M0696_19795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_19805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M0696_19815	COG4585	Histidine kinase
M0696_19820	COG2197	response regulator
M0696_19825	COG2195	Cleaves the N-terminal amino acid of tripeptides
M0696_19835	COG4894	glucomannan catabolic process
M0696_19840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M0696_19845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M0696_19850	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_19855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M0696_19860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M0696_19865	COG2610	gluconate transmembrane transporter activity
M0696_19870	COG0500	methyltransferase
M0696_19875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M0696_19890	COG0753	catalase activity
M0696_19890	COG0693	protein deglycase activity
M0696_19895	COG2851	Citrate transporter
M0696_19900	COG2323	membrane
M0696_19910	COG2723	6-phospho-beta-galactosidase activity
M0696_19915	COG2190	(PTS) system
M0696_19915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_19915	COG1263	PTS System
M0696_19920	COG3711	transcriptional antiterminator
M0696_19930	COG2270	Major facilitator Superfamily
M0696_19935	COG0513	Belongs to the DEAD box helicase family
M0696_19940	COG3401	FG-GAP repeat protein
M0696_19940	COG2755	lipolytic protein G-D-S-L family
M0696_20000	COG0697	spore germination
M0696_20010	COG0861	Integral membrane protein TerC family
M0696_20015	COG0589	response to stress
M0696_20020	COG2723	6-phospho-beta-galactosidase activity
M0696_20025	COG2190	(PTS) system
M0696_20025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_20025	COG1263	PTS System
M0696_20035	COG5444	nuclease activity
M0696_20050	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_20065	COG2986	histidine ammonia-lyase
M0696_20070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
M0696_20075	COG1228	amidohydrolase
M0696_20080	COG0010	Belongs to the arginase family
M0696_20085	COG0833	amino acid
M0696_20090	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M0696_20095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M0696_20100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M0696_20105	COG2390	Transcriptional regulator
M0696_20115	COG3192	ethanolamine utilization protein
M0696_20120	COG2079	MmgE PrpD family protein
M0696_20125	COG1473	amidohydrolase
M0696_20130	COG1126	abc transporter atp-binding protein
M0696_20135	COG0765	amino acid transport
M0696_20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_20145	COG0456	acetyltransferase
M0696_20150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_20155	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M0696_20160	COG0561	phosphatase activity
M0696_20185	COG5294	Protein conserved in bacteria
M0696_20190	COG0577	efflux transmembrane transporter activity
M0696_20195	COG1136	(ABC) transporter
M0696_20200	COG2205	protein histidine kinase activity
M0696_20205	COG0745	RESPONSE REGULATOR receiver
M0696_20215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_20220	COG0191	fructose-bisphosphate aldolase activity
M0696_20225	COG1082	Xylose isomerase domain protein TIM barrel
M0696_20230	COG1082	Xylose isomerase domain protein TIM barrel
M0696_20235	COG0673	inositol 2-dehydrogenase activity
M0696_20240	COG2814	Major facilitator Superfamily
M0696_20245	COG1082	Xylose isomerase domain protein TIM barrel
M0696_20250	COG3962	Belongs to the TPP enzyme family
M0696_20255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_20265	COG1012	belongs to the aldehyde dehydrogenase family
M0696_20270	COG1349	DNA-binding transcription factor activity
M0696_20275	COG0667	Aldo Keto reductase
M0696_20290	COG2814	Major facilitator Superfamily
M0696_20295	COG0326	Molecular chaperone. Has ATPase activity
M0696_20305	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_20310	COG1309	transcriptional regulator
M0696_20315	COG1012	belongs to the aldehyde dehydrogenase family
M0696_20325	COG0667	Aldo Keto reductase
M0696_20330	COG0789	Transcriptional regulator
M0696_20335	COG1714	RDD family
M0696_20340	COG2311	Membrane
M0696_20345	COG1917	Cupin 2, conserved barrel domain protein
M0696_20350	COG1309	transcriptional regulator
M0696_20355	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_20380	COG5039	Polysaccharide pyruvyl transferase
M0696_20385	COG1929	Belongs to the glycerate kinase type-1 family
M0696_20390	COG1802	Transcriptional regulator
M0696_20395	COG1070	Carbohydrate kinase
M0696_20400	COG2610	gluconate transmembrane transporter activity
M0696_20405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M0696_20410	COG0450	alkyl hydroperoxide reductase
M0696_20415	COG3634	alkyl hydroperoxide reductase activity
M0696_20425	COG2723	6-phospho-beta-galactosidase activity
M0696_20430	COG2190	(PTS) system
M0696_20430	COG1263	PTS System
M0696_20430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_20435	COG2188	Transcriptional regulator
M0696_20445	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
M0696_20450	COG1192	Involved in chromosome partitioning
M0696_20470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
M0696_20485	COG1063	alcohol dehydrogenase
M0696_20505	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
M0696_20510	COG0456	acetyltransferase
M0696_20515	COG0457	Tetratricopeptide repeat
M0696_20525	COG0010	Belongs to the arginase family
M0696_20530	COG0833	amino acid
M0696_20535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M0696_20540	COG3829	transcription factor binding
M0696_20545	COG5002	protein histidine kinase activity
M0696_20550	COG0745	RESPONSE REGULATOR receiver
M0696_20570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_20575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M0696_20580	COG4853	Protein conserved in bacteria
M0696_20585	COG4863	YycH protein
M0696_20590	COG5002	protein histidine kinase activity
M0696_20595	COG0745	RESPONSE REGULATOR receiver
M0696_20625	COG0346	lactoylglutathione lyase activity
M0696_20630	COG0305	Participates in initiation and elongation during chromosome replication
M0696_20645	COG3093	addiction module antidote protein HigA
M0696_20650	COG2807	transmembrane transport
M0696_20655	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
M0696_20660	COG0359	binds to the 23S rRNA
M0696_20665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M0696_20670	COG4241	membrane
M0696_20680	COG5577	PFAM Coat F domain
M0696_20685	COG1733	regulation of RNA biosynthetic process
M0696_20690	COG1227	inorganic diphosphatase activity
M0696_20700	COG2271	Major facilitator Superfamily
M0696_20705	COG4978	Transcriptional regulator
M0696_20705	COG0789	Transcriptional regulator
M0696_20725	COG2814	Major facilitator Superfamily
M0696_20730	COG0583	DNA-binding transcription factor activity
M0696_20735	COG2153	protein acetylation
M0696_20745	COG0583	DNA-binding transcription factor activity
M0696_20765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_20770	COG1733	regulation of RNA biosynthetic process
M0696_20790	COG2315	Protein conserved in bacteria
M0696_20820	COG1131	(ABC) transporter
M0696_20850	COG1733	regulation of RNA biosynthetic process
M0696_20855	COG0657	acetylesterase activity
M0696_20860	COG1309	transcriptional regulator
M0696_20865	COG1902	pentaerythritol trinitrate reductase activity
M0696_20870	COG1331	Highly conserved protein containing a thioredoxin domain
M0696_20875	COG1266	CAAX protease self-immunity
M0696_20880	COG2814	Major facilitator Superfamily
M0696_20880	COG0477	Major facilitator Superfamily
M0696_20885	COG0110	maltose O-acetyltransferase activity
M0696_20890	COG0346	lactoylglutathione lyase activity
M0696_20895	COG1609	Transcriptional regulator
M0696_20900	COG0708	Exodeoxyribonuclease III
M0696_20905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M0696_20910	COG0629	single-stranded DNA binding
M0696_20915	COG0360	Binds together with S18 to 16S ribosomal RNA
M0696_20920	COG0012	GTP binding
M0696_20925	COG0243	molybdopterin cofactor binding
M0696_20930	COG4481	Protein conserved in bacteria
M0696_20935	COG3949	Membrane
M0696_20945	COG1475	DNA binding
M0696_20950	COG1192	Involved in chromosome partitioning
M0696_20960	COG1475	DNA binding
M0696_20965	COG0357	Ribosomal RNA small subunit methyltransferase G
M0696_20970	COG0445	tRNA wobble uridine modification
M0696_20975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
M0696_20980	COG1847	R3H domain protein
M0696_20985	COG0706	membrane insertase activity
M0696_20990	COG0594	ribonuclease P activity