locus-tag	class	description
N7921_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
N7921_00010	COG0592	DNA-directed DNA polymerase activity
N7921_00015	COG2501	S4 domain
N7921_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N7921_00030	COG0187	DNA topoisomerase II activity
N7921_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7921_00070	COG0516	GMP reductase activity
N7921_00070	COG0517	IMP dehydrogenase activity
N7921_00075	COG1686	Belongs to the peptidase S11 family
N7921_00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7921_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
N7921_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
N7921_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
N7921_00100	COG0840	transmembrane signaling receptor activity
N7921_00110	COG1428	Deoxynucleoside kinase
N7921_00115	COG1428	Deoxynucleoside kinase
N7921_00120	COG3858	chitin binding
N7921_00120	COG1388	LysM domain
N7921_00125	COG1335	isochorismatase
N7921_00130	COG0590	tRNA wobble adenosine to inosine editing
N7921_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
N7921_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
N7921_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N7921_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
N7921_00200	COG3853	Toxic anion resistance protein (TelA)
N7921_00205	COG1982	Orn Lys Arg decarboxylase major
N7921_00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N7921_00215	COG3870	Protein conserved in bacteria
N7921_00220	COG1728	Protein conserved in bacteria
N7921_00225	COG0470	DNA polymerase III
N7921_00230	COG1774	PSP1 C-terminal conserved region
N7921_00235	COG4467	Involved in initiation control of chromosome replication
N7921_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
N7921_00245	COG2827	Endonuclease containing a URI domain
N7921_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
N7921_00255	COG2002	toxin-antitoxin pair type II binding
N7921_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7921_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7921_00265	COG0084	hydrolase, TatD family'
N7921_00270	COG3583	domain protein
N7921_00270	COG3584	3D domain protein
N7921_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N7921_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N7921_00290	COG4466	Protein conserved in bacteria
N7921_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
N7921_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7921_00310	COG0251	oxidation-reduction process
N7921_00315	COG2088	sporulation resulting in formation of a cellular spore
N7921_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N7921_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
N7921_00335	COG0193	aminoacyl-tRNA hydrolase activity
N7921_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N7921_00350	COG2002	toxin-antitoxin pair type II binding
N7921_00355	COG2244	polysaccharide biosynthetic process
N7921_00360	COG3956	TIGRFAM MazG family protein
N7921_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N7921_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N7921_00385	COG1098	S1 RNA binding domain
N7921_00400	COG2208	phosphoserine phosphatase activity
N7921_00405	COG2304	oxidoreductase activity
N7921_00410	COG0515	serine threonine protein kinase
N7921_00415	COG0037	tRNA processing
N7921_00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
N7921_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N7921_00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
N7921_00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
N7921_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7921_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7921_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
N7921_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
N7921_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7921_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N7921_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
N7921_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N7921_00480	COG1396	sequence-specific DNA binding
N7921_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7921_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
N7921_00570	COG4463	regulation of RNA biosynthetic process
N7921_00575	COG3880	PFAM UvrB UvrC protein
N7921_00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
N7921_00585	COG0542	response to heat
N7921_00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
N7921_00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
N7921_00600	COG4956	integral membrane protein (PIN domain superfamily)
N7921_00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
N7921_00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
N7921_00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N7921_00620	COG1045	serine acetyltransferase
N7921_00625	COG0215	cysteine-tRNA ligase activity
N7921_00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
N7921_00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7921_00645	COG1595	DNA-templated transcription, initiation
N7921_00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N7921_00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7921_00660	COG0250	Participates in transcription elongation, termination and antitermination
N7921_00670	COG0081	regulation of translation
N7921_00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
N7921_00680	COG0222	ribosome binding
N7921_00685	COG2813	Specifically methylates the guanine in position
N7921_00690	COG0085	RNA polymerase activity
N7921_00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
N7921_00700	COG1358	cellular component organization or biogenesis
N7921_00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
N7921_00710	COG0049	tRNA binding
N7921_00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
N7921_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
N7921_00725	COG0596	Alpha beta hydrolase
N7921_00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
N7921_00740	COG0088	Forms part of the polypeptide exit tunnel
N7921_00745	COG0089	rRNA binding
N7921_00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
N7921_00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
N7921_00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
N7921_00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
N7921_00775	COG0255	Belongs to the universal ribosomal protein uL29 family
N7921_00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
N7921_00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
N7921_00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
N7921_00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
N7921_00800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N7921_00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
N7921_00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
N7921_00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
N7921_00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
N7921_00825	COG1841	ribosomal large subunit assembly
N7921_00830	COG0200	Binds to the 23S rRNA
N7921_00835	COG0201	protein transport
N7921_00840	COG0563	adenylate kinase activity
N7921_00845	COG0024	Methionine aminopeptidase
N7921_00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
N7921_00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
N7921_00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
N7921_00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
N7921_00875	COG0202	RNA polymerase activity
N7921_00880	COG0203	ribosomal protein L17
N7921_00885	COG1122	ATPase activity
N7921_00890	COG1122	ATPase activity
N7921_00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N7921_00900	COG0101	tRNA pseudouridine synthase activity
N7921_00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
N7921_00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N7921_00915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7921_00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7921_00945	COG0489	protein tyrosine kinase activity
N7921_00955	COG2194	sulfuric ester hydrolase activity
N7921_00960	COG0726	polysaccharide deacetylase
N7921_00995	COG0385	Bile acid
N7921_01000	COG3876	Protein conserved in bacteria
N7921_01005	COG1472	Belongs to the glycosyl hydrolase 3 family
N7921_01010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7921_01015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_01015	COG1263	PTS System
N7921_01020	COG1737	Transcriptional regulator
N7921_01025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
N7921_01060	COG1595	DNA-templated transcription, initiation
N7921_01065	COG5662	AntiSigma factor
N7921_01070	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N7921_01075	COG4856	YbbR-like protein
N7921_01080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7921_01085	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N7921_01100	COG1131	(ABC) transporter
N7921_01115	COG1131	(ABC) transporter
N7921_01125	COG1413	lyase activity
N7921_01135	COG2311	Membrane
N7921_01165	COG1131	(ABC) transporter
N7921_01180	COG1113	amino acid transport
N7921_01185	COG0584	glycerophosphoryl diester phosphodiesterase
N7921_01190	COG2271	Major facilitator Superfamily
N7921_01200	COG1331	Highly conserved protein containing a thioredoxin domain
N7921_01205	COG1331	Highly conserved protein containing a thioredoxin domain
N7921_01210	COG2364	Membrane
N7921_01215	COG2153	protein acetylation
N7921_01220	COG1846	Transcriptional regulator
N7921_01230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7921_01250	COG1937	Protein conserved in bacteria
N7921_01255	COG2210	Belongs to the sulfur carrier protein TusA family
N7921_01265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7921_01265	COG0425	Belongs to the sulfur carrier protein TusA family
N7921_01270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7921_01270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7921_01275	COG0425	Belongs to the sulfur carrier protein TusA family
N7921_01280	COG0730	response to heat
N7921_01290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7921_01295	COG2814	Major facilitator Superfamily
N7921_01305	COG1846	Transcriptional regulator
N7921_01315	COG1683	Conserved Protein
N7921_01325	COG0656	L-ascorbic acid biosynthetic process
N7921_01330	COG0371	Dehydrogenase
N7921_01335	COG1054	Belongs to the UPF0176 family
N7921_01340	COG0531	amino acid
N7921_01350	COG3711	transcriptional antiterminator
N7921_01355	COG2190	(PTS) system
N7921_01355	COG1263	PTS System
N7921_01355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_01360	COG2723	6-phospho-beta-galactosidase activity
N7921_01380	COG3711	transcriptional antiterminator
N7921_01380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_01385	COG1940	carbohydrate kinase activity
N7921_01390	COG0383	alpha-mannosidase activity
N7921_01395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_01400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_01410	COG1404	Belongs to the peptidase S8 family
N7921_01430	COG0833	amino acid
N7921_01435	COG2040	homocysteine
N7921_01440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7921_01445	COG1695	Transcriptional regulator
N7921_01460	COG2814	Major facilitator Superfamily
N7921_01465	COG0456	acetyltransferase
N7921_01480	COG1404	Belongs to the peptidase S8 family
N7921_01490	COG1309	transcriptional regulator
N7921_01495	COG1917	Cupin 2, conserved barrel domain protein
N7921_01500	COG1063	alcohol dehydrogenase
N7921_01505	COG1846	Transcriptional regulator
N7921_01510	COG0318	PFAM AMP-dependent synthetase and ligase
N7921_01515	COG0531	amino acid
N7921_01525	COG0596	Alpha beta hydrolase
N7921_01530	COG1115	amino acid carrier protein
N7921_01535	COG2066	Belongs to the glutaminase family
N7921_01540	COG4191	Histidine kinase
N7921_01545	COG0784	Response regulator, receiver
N7921_01550	COG1405	negative regulation of cell septum assembly
N7921_01550	COG3012	SEC-C Motif Domain Protein
N7921_01560	COG2197	response regulator
N7921_01565	COG4585	Histidine kinase
N7921_01575	COG0667	Aldo Keto reductase
N7921_01580	COG3290	protein histidine kinase activity
N7921_01585	COG3279	Response regulator of the LytR AlgR family
N7921_01590	COG4555	ABC transporter
N7921_01595	COG1668	transmembrane transport
N7921_01610	COG3773	Cell wall hydrolase
N7921_01615	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_01625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7921_01630	COG2310	stress, protein
N7921_01635	COG2310	stress, protein
N7921_01640	COG2310	stress, protein
N7921_01645	COG0861	Integral membrane protein TerC family
N7921_01675	COG3853	Toxic anion resistance protein (TelA)
N7921_01680	COG0517	IMP dehydrogenase activity
N7921_01680	COG4175	Glycine betaine
N7921_01685	COG4176	ABC-type proline glycine betaine transport system permease component
N7921_01690	COG2113	Glycine betaine
N7921_01705	COG1473	amidohydrolase
N7921_01710	COG1288	antiporter activity
N7921_01715	COG0039	L-malate dehydrogenase activity
N7921_01720	COG1620	l-lactate permease
N7921_01725	COG1609	Transcriptional regulator
N7921_01730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7921_01735	COG0561	phosphatase activity
N7921_01740	COG0673	inositol 2-dehydrogenase activity
N7921_01745	COG0738	Major facilitator superfamily
N7921_01750	COG1280	lysine exporter protein (LysE YggA)
N7921_01760	COG3403	YqcI/YcgG family
N7921_01765	COG1113	amino acid transport
N7921_01770	COG3665	Urea carboxylase-associated protein
N7921_01775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N7921_01785	COG1012	belongs to the aldehyde dehydrogenase family
N7921_01790	COG0710	3-dehydroquinate dehydratase activity
N7921_01795	COG0028	Belongs to the TPP enzyme family
N7921_01805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N7921_01810	COG2271	Major facilitator Superfamily
N7921_01825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
N7921_01830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7921_01840	COG0477	Major facilitator Superfamily
N7921_01845	COG2226	methyltransferase
N7921_01850	COG0583	DNA-binding transcription factor activity
N7921_01855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7921_01860	COG3458	cephalosporin-C deacetylase activity
N7921_01870	COG3541	Predicted nucleotidyltransferase
N7921_01875	COG0506	proline dehydrogenase activity
N7921_01880	COG1012	belongs to the aldehyde dehydrogenase family
N7921_01885	COG2508	Transcriptional regulator
N7921_01890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
N7921_01895	COG0765	amino acid transport
N7921_01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_01910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N7921_01915	COG1522	sequence-specific DNA binding
N7921_01920	COG2746	aminoglycoside 3-N-acetyltransferase activity
N7921_01930	COG0840	transmembrane signaling receptor activity
N7921_01930	COG3290	protein histidine kinase activity
N7921_01935	COG3209	COG3209 Rhs family protein
N7921_01955	COG3842	ATPase activity
N7921_01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7921_01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7921_01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7921_01995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N7921_02000	COG0697	spore germination
N7921_02005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7921_02020	COG2364	Membrane
N7921_02025	COG0737	Belongs to the 5'-nucleotidase family
N7921_02030	COG3764	Sortase (surface protein transpeptidase)
N7921_02035	COG2002	toxin-antitoxin pair type II binding
N7921_02040	COG1126	abc transporter atp-binding protein
N7921_02045	COG0765	amino acid transport
N7921_02050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_02055	COG0412	Dienelactone hydrolase
N7921_02060	COG0833	amino acid
N7921_02065	COG3104	oligopeptide transport
N7921_02070	COG5434	Belongs to the glycosyl hydrolase 28 family
N7921_02075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7921_02080	COG0456	acetyltransferase
N7921_02085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_02090	COG0765	amino acid transport
N7921_02095	COG1126	abc transporter atp-binding protein
N7921_02100	COG1473	amidohydrolase
N7921_02105	COG2079	MmgE PrpD family protein
N7921_02110	COG0745	RESPONSE REGULATOR receiver
N7921_02115	COG3850	Histidine kinase
N7921_02115	COG5002	protein histidine kinase activity
N7921_02120	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_02125	COG0527	aspartate kinase activity
N7921_02130	COG2814	Major facilitator Superfamily
N7921_02135	COG1309	transcriptional regulator
N7921_02145	COG0640	Transcriptional regulator
N7921_02150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7921_02155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N7921_02160	COG0531	amino acid
N7921_02165	COG1012	belongs to the aldehyde dehydrogenase family
N7921_02170	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7921_02175	COG4549	nuclear export factor GLE1
N7921_02180	COG2372	response to copper ion
N7921_02180	COG1276	copper resistance
N7921_02185	COG2213	PTS system mannitol-specific
N7921_02190	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_02195	COG0246	Mannitol dehydrogenase
N7921_02200	COG0840	transmembrane signaling receptor activity
N7921_02220	COG0346	lactoylglutathione lyase activity
N7921_02230	COG0561	phosphatase activity
N7921_02235	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
N7921_02240	COG1914	H( )-stimulated, divalent metal cation uptake system
N7921_02245	COG4336	lyase activity
N7921_02250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
N7921_02255	COG1984	allophanate hydrolase subunit 2
N7921_02260	COG1414	Transcriptional regulator
N7921_02265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7921_02270	COG2755	lipolytic protein G-D-S-L family
N7921_02280	COG3711	transcriptional antiterminator
N7921_02285	COG2226	methyltransferase
N7921_02290	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_02295	COG3871	stress protein (general stress protein 26)
N7921_02320	COG2814	Major facilitator Superfamily
N7921_02325	COG1802	Transcriptional regulator
N7921_02330	COG1917	Cupin 2, conserved barrel domain protein
N7921_02330	COG2207	Transcriptional regulator
N7921_02335	COG0697	spore germination
N7921_02340	COG0473	3-isopropylmalate dehydrogenase activity
N7921_02345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7921_02345	COG0551	DNA topoisomerase type I activity
N7921_02350	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
N7921_02355	COG3706	GGDEF domain
N7921_02360	COG5298	Protein conserved in bacteria
N7921_02365	COG1215	transferase activity, transferring glycosyl groups
N7921_02375	COG0531	amino acid
N7921_02380	COG0028	Belongs to the TPP enzyme family
N7921_02385	COG5444	nuclease activity
N7921_02410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7921_02415	COG1914	H( )-stimulated, divalent metal cation uptake system
N7921_02420	COG2261	transglycosylase associated protein
N7921_02425	COG2217	Heavy metal translocating P-type atpase
N7921_02430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
N7921_02435	COG3290	protein histidine kinase activity
N7921_02440	COG4565	transcriptional regulatory protein
N7921_02445	COG1301	dicarboxylic acid transport
N7921_02450	COG0628	permease
N7921_02455	COG1301	dicarboxylic acid transport
N7921_02460	COG1131	(ABC) transporter
N7921_02465	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7921_02480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_02485	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7921_02490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N7921_02505	COG0513	Belongs to the DEAD box helicase family
N7921_02510	COG3402	PFAM membrane-flanked domain
N7921_02515	COG3428	Bacterial PH domain
N7921_02520	COG0705	Rhomboid family
N7921_02525	COG0736	holo-[acyl-carrier-protein] synthase activity
N7921_02530	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N7921_02535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7921_02540	COG0864	Transcriptional regulator
N7921_02545	COG2337	Toxic component of a toxin-antitoxin (TA) module
N7921_02550	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_02555	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_02560	COG2172	sigma factor antagonist activity
N7921_02565	COG2208	phosphoserine phosphatase activity
N7921_02570	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_02575	COG2172	sigma factor antagonist activity
N7921_02580	COG1191	sigma factor activity
N7921_02585	COG2208	phosphoserine phosphatase activity
N7921_02590	COG2183	response to ionizing radiation
N7921_02600	COG3091	SprT-like family
N7921_02605	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7921_02610	COG0022	dehydrogenase e1 component
N7921_02615	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7921_02620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7921_02625	COG3284	Transcriptional regulator
N7921_02670	COG4585	Histidine kinase
N7921_02675	COG2197	response regulator
N7921_02690	COG1278	Cold shock
N7921_02695	COG1329	Transcriptional regulator
N7921_02700	COG1064	alcohol dehydrogenase
N7921_02705	COG0789	Transcriptional regulator
N7921_02720	COG0477	Major facilitator Superfamily
N7921_02725	COG0657	acetylesterase activity
N7921_02735	COG4221	oxidoreductase activity
N7921_02745	COG0252	asparaginase activity
N7921_02765	COG2814	Major facilitator Superfamily
N7921_02770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7921_02800	COG1309	transcriptional regulator
N7921_02805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7921_02810	COG1846	Transcriptional regulator
N7921_02815	COG0778	Nitroreductase
N7921_02830	COG1396	sequence-specific DNA binding
N7921_02840	COG0456	acetyltransferase
N7921_02850	COG4122	O-methyltransferase activity
N7921_02860	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N7921_02865	COG0697	spore germination
N7921_02875	COG1301	dicarboxylic acid transport
N7921_02915	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N7921_02920	COG0802	atpase or kinase
N7921_02925	COG1214	PFAM Peptidase M22, glycoprotease
N7921_02930	COG0456	acetyltransferase
N7921_02935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
N7921_02940	COG0488	(ABC) transporter
N7921_02945	COG0315	cyclic pyranopterin monophosphate synthase activity
N7921_02950	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
N7921_02955	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
N7921_02960	COG0805	protein transport
N7921_02975	COG1266	CAAX protease self-immunity
N7921_02980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
N7921_02985	COG0459	protein refolding
N7921_02995	COG2808	Putative FMN-binding domain
N7921_03025	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
N7921_03030	COG0823	Involved in the tonB-independent uptake of proteins
N7921_03040	COG2132	Multicopper oxidase
N7921_03045	COG1113	amino acid transport
N7921_03050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7921_03055	COG0714	Associated with various cellular activities
N7921_03060	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
N7921_03065	COG1305	Transglutaminase-like
N7921_03070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N7921_03070	COG0519	Catalyzes the synthesis of GMP from XMP
N7921_03075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N7921_03085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7921_03090	COG2207	Transcriptional regulator
N7921_03105	COG0326	Molecular chaperone. Has ATPase activity
N7921_03125	COG1595	DNA-templated transcription, initiation
N7921_03135	COG2814	Major facilitator Superfamily
N7921_03145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7921_03155	COG0457	Tetratricopeptide repeat
N7921_03165	COG5444	nuclease activity
N7921_03190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7921_03260	COG2433	Pfam Transposase IS66
N7921_03320	COG0582	viral genome integration into host DNA
N7921_03415	COG4373	Mu-like prophage FluMu protein gp28
N7921_03435	COG0776	regulation of translation
N7921_03540	COG0582	viral genome integration into host DNA
N7921_03555	COG3655	Transcriptional regulator
N7921_03580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7921_03585	COG0328	RNA-DNA hybrid ribonuclease activity
N7921_03630	COG1793	dna ligase
N7921_03715	COG2887	Belongs to the helicase family. UvrD subfamily
N7921_03725	COG0305	Participates in initiation and elongation during chromosome replication
N7921_03730	COG0358	DNA primase activity
N7921_03735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7921_03740	COG0587	DNA-directed DNA polymerase activity
N7921_03750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
N7921_03760	COG0270	DNA (cytosine-5-)-methyltransferase activity
N7921_03825	COG1780	Probably involved in ribonucleotide reductase function
N7921_03830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7921_03835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7921_03885	COG0756	dUTP diphosphatase activity
N7921_03910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N7921_03985	COG1435	thymidine kinase activity
N7921_04005	COG3331	DNA recombination
N7921_04020	COG2252	PERMEase
N7921_04035	COG3064	Membrane
N7921_04040	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
N7921_04050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
N7921_04055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N7921_04060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N7921_04065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
N7921_04070	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7921_04075	COG0047	phosphoribosylformylglycinamidine synthase activity
N7921_04080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N7921_04085	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
N7921_04090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
N7921_04095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N7921_04100	COG0138	bifunctional purine biosynthesis protein purh
N7921_04105	COG0151	Belongs to the GarS family
N7921_04125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7921_04130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N7921_04135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N7921_04140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7921_04150	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7921_04155	COG4496	protein, YerC YecD
N7921_04165	COG0069	glutamate synthase activity
N7921_04180	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
N7921_04185	COG0210	DNA helicase
N7921_04190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
N7921_04195	COG4851	CamS sex pheromone cAM373 precursor
N7921_04200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7921_04205	COG1285	pathogenesis
N7921_04210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7921_04215	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7921_04220	COG0154	amidase activity
N7921_04225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N7921_04230	COG1309	transcriptional regulator
N7921_04235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7921_04240	COG1957	nucleoside hydrolase
N7921_04245	COG1597	lipid kinase activity
N7921_04250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7921_04255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N7921_04265	COG1737	Transcriptional regulator
N7921_04270	COG1263	PTS System
N7921_04270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_04275	COG1486	melibiose metabolic process
N7921_04285	COG1959	2 iron, 2 sulfur cluster binding
N7921_04290	COG0492	ferredoxin-NADP+ reductase activity
N7921_04305	COG1486	melibiose metabolic process
N7921_04315	COG2211	Major facilitator Superfamily
N7921_04345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N7921_04350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7921_04355	COG1442	glycosyl transferase family 8
N7921_04360	COG1216	Glycosyl transferase, family 2
N7921_04365	COG1442	glycosyl transferase family 8
N7921_04370	COG2223	nitrite transmembrane transporter activity
N7921_04380	COG0471	metal ion transport
N7921_04395	COG0071	Belongs to the small heat shock protein (HSP20) family
N7921_04410	COG0531	amino acid
N7921_04415	COG0463	Glycosyl transferase, family 2
N7921_04420	COG0488	(ABC) transporter
N7921_04425	COG1469	GTP cyclohydrolase I activity
N7921_04430	COG0789	Transcriptional regulator
N7921_04435	COG2814	Major facilitator Superfamily
N7921_04440	COG0488	(ABC) transporter
N7921_04445	COG0513	Belongs to the DEAD box helicase family
N7921_04450	COG2130	NADP-dependent
N7921_04470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7921_04470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7921_04475	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N7921_04485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7921_04485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7921_04495	COG3290	protein histidine kinase activity
N7921_04500	COG4565	transcriptional regulatory protein
N7921_04505	COG3181	Tripartite tricarboxylate transporter family receptor
N7921_04510	COG2851	Citrate transporter
N7921_04520	COG3479	Phenolic acid decarboxylase
N7921_04525	COG1695	Transcriptional regulator
N7921_04530	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
N7921_04535	COG0477	Major facilitator Superfamily
N7921_04540	COG0583	DNA-binding transcription factor activity
N7921_04550	COG1254	Belongs to the acylphosphatase family
N7921_04555	COG2258	MOSC domain
N7921_04570	COG0024	Methionine aminopeptidase
N7921_04575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_04575	COG1263	PTS System
N7921_04580	COG3739	integral membrane protein
N7921_04600	COG1368	sulfuric ester hydrolase activity
N7921_04605	COG0076	glutamate decarboxylase activity
N7921_04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_04620	COG1263	PTS System
N7921_04625	COG0366	Alpha amylase catalytic
N7921_04630	COG2188	Transcriptional regulator
N7921_04640	COG0737	Belongs to the 5'-nucleotidase family
N7921_04645	COG0693	protein deglycase activity
N7921_04650	COG4840	Belongs to the UPF0435 family
N7921_04655	COG1115	amino acid carrier protein
N7921_04660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7921_04665	COG4980	gas vesicle protein
N7921_04670	COG1295	ribonuclease BN
N7921_04680	COG0477	Major facilitator Superfamily
N7921_04690	COG0387	Pfam Sodium calcium exchanger
N7921_04700	COG0217	transcriptional regulatory protein
N7921_04705	COG0668	transmembrane transport
N7921_04710	COG0535	radical SAM domain protein
N7921_04720	COG0726	polysaccharide deacetylase
N7921_04730	COG0598	Magnesium transport protein CorA
N7921_04740	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
N7921_04745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
N7921_04770	COG0789	Transcriptional regulator
N7921_04775	COG2814	Major facilitator Superfamily
N7921_04790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7921_04830	COG2076	Multidrug Resistance protein
N7921_04835	COG2076	Multidrug Resistance protein
N7921_04840	COG1309	transcriptional regulator
N7921_04850	COG4637	Psort location Cytoplasmic, score
N7921_04855	COG2755	lipolytic protein G-D-S-L family
N7921_04860	COG0492	ferredoxin-NADP+ reductase activity
N7921_04865	COG2169	Transcriptional regulator
N7921_04870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_04875	COG1132	(ABC) transporter
N7921_04880	COG1742	UPF0060 membrane protein
N7921_04885	COG1595	DNA-templated transcription, initiation
N7921_04905	COG2318	DinB family
N7921_04915	COG1846	Transcriptional regulator
N7921_04920	COG0392	lysyltransferase activity
N7921_04920	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
N7921_04940	COG0778	Nitroreductase
N7921_04955	COG1090	epimerase
N7921_04960	COG2137	regulation of response to DNA damage stimulus
N7921_04985	COG0463	Glycosyl transferase, family 2
N7921_04990	COG4485	Bacterial membrane protein, YfhO
N7921_04995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N7921_05010	COG2140	Oxalate decarboxylase
N7921_05020	COG1191	sigma factor activity
N7921_05030	COG1988	membrane-bound metal-dependent
N7921_05035	COG1194	a g-specific adenine glycosylase
N7921_05045	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_05060	COG3557	Belongs to the UPF0374 family
N7921_05065	COG1132	(ABC) transporter
N7921_05070	COG0444	Belongs to the ABC transporter superfamily
N7921_05075	COG4608	Belongs to the ABC transporter superfamily
N7921_05080	COG0747	negative chemotaxis
N7921_05085	COG0601	transmembrane transport
N7921_05090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7921_05095	COG4129	membrane
N7921_05100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N7921_05105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N7921_05110	COG0735	belongs to the Fur family
N7921_05260	COG1368	sulfuric ester hydrolase activity
N7921_05265	COG0681	Belongs to the peptidase S26 family
N7921_05270	COG2873	o-acetylhomoserine
N7921_05280	COG1116	anion transmembrane transporter activity
N7921_05285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7921_05290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7921_05305	COG1131	(ABC) transporter
N7921_05335	COG3382	B3 4 domain protein
N7921_05340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N7921_05350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N7921_05355	COG2766	serine protein kinase
N7921_05360	COG2718	Belongs to the UPF0229 family
N7921_05365	COG1566	PFAM secretion protein HlyD family protein
N7921_05370	COG2814	Major facilitator Superfamily
N7921_05375	COG0655	NAD(P)H dehydrogenase (quinone) activity
N7921_05385	COG1278	Cold shock
N7921_05390	COG3706	GGDEF domain
N7921_05415	COG5577	PFAM Coat F domain
N7921_05420	COG5002	protein histidine kinase activity
N7921_05425	COG0737	Belongs to the 5'-nucleotidase family
N7921_05425	COG1525	nuclease
N7921_05425	COG4085	toxin activity
N7921_05430	COG3764	Sortase (surface protein transpeptidase)
N7921_05435	COG0564	pseudouridine synthase activity
N7921_05445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N7921_05450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N7921_05450	COG3153	acetyltransferase
N7921_05465	COG3835	regulator
N7921_05470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
N7921_05475	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
N7921_05480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
N7921_05485	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N7921_05490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
N7921_05495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N7921_05500	COG2203	Gaf domain
N7921_05500	COG4585	Histidine kinase
N7921_05505	COG2197	response regulator
N7921_05520	COG0753	catalase activity
N7921_05525	COG1959	2 iron, 2 sulfur cluster binding
N7921_05530	COG1017	nitric oxide dioxygenase activity
N7921_05530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N7921_05535	COG2719	SpoVR family
N7921_05540	COG1785	Belongs to the alkaline phosphatase family
N7921_05545	COG0791	NLP P60 protein
N7921_05545	COG1388	LysM domain
N7921_05550	COG0531	amino acid
N7921_05565	COG1595	DNA-templated transcription, initiation
N7921_05570	COG0204	Acyl-transferase
N7921_05575	COG1253	flavin adenine dinucleotide binding
N7921_05580	COG0789	Transcriptional regulator
N7921_05585	COG1253	flavin adenine dinucleotide binding
N7921_05595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7921_05600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
N7921_05605	COG0584	glycerophosphoryl diester phosphodiesterase
N7921_05615	COG0668	transmembrane transport
N7921_05620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N7921_05625	COG0726	polysaccharide deacetylase
N7921_05630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7921_05635	COG0589	response to stress
N7921_05640	COG1132	(ABC) transporter
N7921_05645	COG1132	(ABC) transporter
N7921_05655	COG0702	epimerase
N7921_05665	COG3842	ATPase activity
N7921_05670	COG2508	Transcriptional regulator
N7921_05680	COG0189	ligase activity
N7921_05685	COG0189	ligase activity
N7921_05690	COG4399	Belongs to the UPF0754 family
N7921_05695	COG3679	Belongs to the UPF0342 family
N7921_05700	COG0561	phosphatase activity
N7921_05705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7921_05715	COG0475	glutathione-regulated potassium exporter activity
N7921_05720	COG0490	domain, Protein
N7921_05730	COG1024	Enoyl-CoA hydratase
N7921_05740	COG0420	3'-5' exonuclease activity
N7921_05745	COG4717	serine-type aminopeptidase activity
N7921_05750	COG3481	metal-dependent phosphohydrolase, HD sub domain
N7921_05760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N7921_05790	COG1846	Transcriptional regulator
N7921_05795	COG4980	gas vesicle protein
N7921_05810	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
N7921_05815	COG0537	adenosine 5'-monophosphoramidase activity
N7921_05820	COG1131	(ABC) transporter
N7921_05825	COG4473	ABC transporter
N7921_05835	COG1473	amidohydrolase
N7921_05845	COG2329	Antibiotic biosynthesis monooxygenase
N7921_05850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7921_05855	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
N7921_05860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
N7921_05865	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
N7921_05870	COG1309	transcriptional regulator
N7921_05875	COG1511	domain protein
N7921_05880	COG1363	Peptidase, m42
N7921_05885	COG1301	dicarboxylic acid transport
N7921_05895	COG1234	tRNA 3'-trailer cleavage
N7921_05900	COG0095	Lipoate-protein ligase
N7921_05905	COG0318	PFAM AMP-dependent synthetase and ligase
N7921_05915	COG0501	Belongs to the peptidase M48B family
N7921_05920	COG1404	Belongs to the peptidase S8 family
N7921_05925	COG0406	alpha-ribazole phosphatase activity
N7921_05930	COG0840	transmembrane signaling receptor activity
N7921_05935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N7921_05935	COG0723	plastoquinol--plastocyanin reductase activity
N7921_05940	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_05950	COG4903	ComK protein
N7921_05960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7921_05965	COG2814	Major facilitator Superfamily
N7921_05970	COG2732	(Barnase) inhibitor
N7921_05975	COG1316	TRANSCRIPTIONal
N7921_05985	COG0398	Pfam SNARE associated Golgi protein
N7921_05990	COG0681	Belongs to the peptidase S26 family
N7921_05995	COG3180	Ammonia monooxygenase
N7921_06005	COG0501	Belongs to the peptidase M48B family
N7921_06010	COG2259	Doxx family
N7921_06015	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
N7921_06020	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
N7921_06025	COG1074	ATP-dependent DNA helicase activity
N7921_06030	COG0420	3'-5' exonuclease activity
N7921_06035	COG0419	ATPase involved in DNA repair
N7921_06040	COG1403	HNH endonuclease
N7921_06080	COG5337	Spore coat protein CotH
N7921_06090	COG0179	Fumarylacetoacetate (FAA) hydrolase
N7921_06105	COG0367	asparagine synthase
N7921_06120	COG1562	ergosterol biosynthetic process
N7921_06125	COG0534	Mate efflux family protein
N7921_06130	COG2207	Transcriptional regulator
N7921_06130	COG1917	Cupin 2, conserved barrel domain protein
N7921_06160	COG0076	glutamate decarboxylase activity
N7921_06195	COG1410	methionine synthase
N7921_06195	COG0646	methionine synthase
N7921_06200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N7921_06200	COG0646	methionine synthase
N7921_06205	COG1666	GTP binding
N7921_06210	COG2996	Protein conserved in bacteria
N7921_06215	COG1744	ABC transporter substrate-binding protein PnrA-like
N7921_06220	COG0840	transmembrane signaling receptor activity
N7921_06225	COG1307	EDD domain protein, DegV family
N7921_06230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7921_06250	COG0561	phosphatase activity
N7921_06255	COG1073	alpha beta
N7921_06260	COG2151	metal-sulfur cluster biosynthetic enzyme
N7921_06265	COG0277	FAD linked oxidase domain protein
N7921_06270	COG2271	Major facilitator Superfamily
N7921_06275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
N7921_06280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N7921_06285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
N7921_06290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7921_06295	COG0505	Belongs to the CarA family
N7921_06300	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7921_06305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
N7921_06315	COG2814	Major facilitator Superfamily
N7921_06325	COG2267	carboxylic ester hydrolase activity
N7921_06335	COG1744	ABC transporter substrate-binding protein PnrA-like
N7921_06350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7921_06355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
N7921_06360	COG5504	Zn-dependent protease
N7921_06365	COG0444	Belongs to the ABC transporter superfamily
N7921_06370	COG4608	Belongs to the ABC transporter superfamily
N7921_06380	COG0601	transmembrane transport
N7921_06385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7921_06395	COG0180	Tryptophanyl-tRNA synthetase
N7921_06405	COG4166	transmembrane transport
N7921_06410	COG0601	transmembrane transport
N7921_06415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7921_06420	COG0444	Belongs to the ABC transporter superfamily
N7921_06425	COG4608	Belongs to the ABC transporter superfamily
N7921_06435	COG0456	acetyltransferase
N7921_06440	COG1393	Belongs to the ArsC family
N7921_06445	COG0861	Integral membrane protein TerC family
N7921_06450	COG4862	establishment of competence for transformation
N7921_06455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7921_06465	COG1164	Oligoendopeptidase f
N7921_06475	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N7921_06480	COG2346	COG2346, Truncated hemoglobins
N7921_06485	COG0741	lytic transglycosylase activity
N7921_06490	COG4116	CYTH
N7921_06500	COG2357	RelA SpoT domain protein
N7921_06505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7921_06510	COG0564	pseudouridine synthase activity
N7921_06515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N7921_06520	COG0475	glutathione-regulated potassium exporter activity
N7921_06520	COG0569	domain protein
N7921_06525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7921_06530	COG0352	thiamine-phosphate diphosphorylase activity
N7921_06540	COG2104	thiamine diphosphate biosynthetic process
N7921_06545	COG2022	thiamine diphosphate biosynthetic process
N7921_06550	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N7921_06555	COG0351	phosphomethylpyrimidine kinase
N7921_06560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
N7921_06620	COG0210	DNA helicase
N7921_06635	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N7921_06640	COG2382	esterase
N7921_06645	COG0626	cystathionine gamma-synthase activity
N7921_06650	COG0626	cystathionine gamma-synthase activity
N7921_06690	COG0825	malonyl-CoA metabolic process
N7921_06710	COG2807	transmembrane transport
N7921_06720	COG0583	DNA-binding transcription factor activity
N7921_06735	COG0457	Tetratricopeptide repeat
N7921_06755	COG3173	Aminoglycoside phosphotransferase
N7921_06760	COG0583	DNA-binding transcription factor activity
N7921_06780	COG0583	DNA-binding transcription factor activity
N7921_06785	COG2807	transmembrane transport
N7921_06835	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N7921_06855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7921_06860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7921_06865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7921_06885	COG4195	phage-related replication protein
N7921_06890	COG2856	Zn peptidase
N7921_06895	COG3409	Peptidoglycan-binding domain 1 protein
N7921_06895	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7921_06915	COG0306	phosphate transporter
N7921_06920	COG1392	Phosphate transport regulator
N7921_06930	COG0405	Gamma-glutamyltransferase
N7921_06935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N7921_06945	COG4208	sulfate ABC transporter
N7921_06950	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N7921_06960	COG3775	system Galactitol-specific IIC component
N7921_06975	COG1063	alcohol dehydrogenase
N7921_06980	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7921_06985	COG0022	dehydrogenase e1 component
N7921_06985	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7921_06990	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7921_06995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7921_07000	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_07005	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_07010	COG2390	Transcriptional regulator
N7921_07020	COG0531	amino acid
N7921_07025	COG0346	lactoylglutathione lyase activity
N7921_07030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7921_07035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7921_07040	COG2362	D-Aminopeptidase
N7921_07045	COG0601	transmembrane transport
N7921_07050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7921_07055	COG0444	Belongs to the ABC transporter superfamily
N7921_07060	COG4166	transmembrane transport
N7921_07065	COG1619	proteins homologs of microcin C7 resistance protein MccF
N7921_07070	COG4948	Mandelate Racemase Muconate Lactonizing
N7921_07075	COG0791	NLP P60 protein
N7921_07080	COG4608	Belongs to the ABC transporter superfamily
N7921_07085	COG1834	amidinotransferase
N7921_07090	COG1607	acyl-coa hydrolase
N7921_07095	COG1695	Transcriptional regulator
N7921_07110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7921_07125	COG2076	Multidrug Resistance protein
N7921_07130	COG2076	Multidrug Resistance protein
N7921_07140	COG0788	formyltetrahydrofolate deformylase activity
N7921_07145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7921_07150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N7921_07155	COG0457	Tetratricopeptide repeat
N7921_07165	COG1764	response to oxidative stress
N7921_07170	COG1846	Transcriptional regulator
N7921_07175	COG1764	response to oxidative stress
N7921_07180	COG0590	tRNA wobble adenosine to inosine editing
N7921_07185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7921_07190	COG1404	Belongs to the peptidase S8 family
N7921_07195	COG0745	RESPONSE REGULATOR receiver
N7921_07200	COG5002	protein histidine kinase activity
N7921_07200	COG3850	Histidine kinase
N7921_07205	COG3212	peptidase
N7921_07210	COG3212	peptidase
N7921_07220	COG2239	Acts as a magnesium transporter
N7921_07230	COG0583	DNA-binding transcription factor activity
N7921_07240	COG0789	Transcriptional regulator
N7921_07255	COG1846	Transcriptional regulator
N7921_07260	COG5001	Diguanylate cyclase
N7921_07260	COG3300	MHYT domain
N7921_07265	COG0586	Pfam SNARE associated Golgi protein
N7921_07275	COG1191	sigma factor activity
N7921_07295	COG0501	Belongs to the peptidase M48B family
N7921_07300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N7921_07305	COG2323	membrane
N7921_07320	COG3594	Acyltransferase
N7921_07325	COG5002	protein histidine kinase activity
N7921_07330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N7921_07340	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
N7921_07345	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
N7921_07350	COG0436	Aminotransferase
N7921_07355	COG1850	ribulose-bisphosphate carboxylase activity
N7921_07360	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
N7921_07365	COG0235	Class ii aldolase
N7921_07370	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
N7921_07380	COG3852	Histidine kinase
N7921_07385	COG1846	Transcriptional regulator
N7921_07390	COG1360	Flagellar Motor Protein
N7921_07395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
N7921_07400	COG0542	response to heat
N7921_07405	COG3949	Membrane
N7921_07410	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N7921_07415	COG0720	synthase
N7921_07420	COG0602	queuosine metabolic process
N7921_07425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
N7921_07435	COG4873	Protein conserved in bacteria
N7921_07445	COG3773	Cell wall hydrolase
N7921_07450	COG2244	polysaccharide biosynthetic process
N7921_07455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_07460	COG2217	Heavy metal translocating P-type atpase
N7921_07465	COG0006	proline dipeptidase activity
N7921_07475	COG1609	Transcriptional regulator
N7921_07480	COG3711	transcriptional antiterminator
N7921_07485	COG2190	(PTS) system
N7921_07485	COG1263	PTS System
N7921_07485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_07490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_07495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N7921_07505	COG1533	DNA photolyase activity
N7921_07510	COG0840	transmembrane signaling receptor activity
N7921_07520	COG2084	Dehydrogenase
N7921_07525	COG2340	Cysteine-rich secretory protein family
N7921_07530	COG0768	penicillin binding
N7921_07535	COG4191	Histidine kinase
N7921_07540	COG0436	Aminotransferase
N7921_07545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
N7921_07555	COG1714	RDD family
N7921_07565	COG0784	Response regulator, receiver
N7921_07565	COG0835	chemotaxis
N7921_07580	COG2207	Transcriptional regulator
N7921_07580	COG1917	Cupin 2, conserved barrel domain protein
N7921_07585	COG0697	spore germination
N7921_07595	COG2814	Major facilitator Superfamily
N7921_07600	COG1376	ErfK ybiS ycfS ynhG family protein
N7921_07605	COG1408	metallophosphoesterase
N7921_07610	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_07615	COG2200	EAL domain
N7921_07620	COG3546	catalase activity
N7921_07625	COG4703	Protein of unknown function (DUF1797)
N7921_07630	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
N7921_07640	COG0517	IMP dehydrogenase activity
N7921_07645	COG0583	DNA-binding transcription factor activity
N7921_07650	COG0716	FMN binding
N7921_07660	COG0716	FMN binding
N7921_07665	COG2171	N-acyltransferase activity
N7921_07670	COG1473	amidohydrolase
N7921_07680	COG0668	transmembrane transport
N7921_07685	COG0450	alkyl hydroperoxide reductase
N7921_07690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_07705	COG0746	molybdenum cofactor guanylyltransferase activity
N7921_07710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N7921_07715	COG0303	'Molybdopterin
N7921_07720	COG1763	Mo-molybdopterin cofactor biosynthetic process
N7921_07725	COG0314	molybdopterin synthase activity
N7921_07730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
N7921_07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N7921_07750	COG1136	(ABC) transporter
N7921_07755	COG0577	efflux transmembrane transporter activity
N7921_07760	COG1349	DNA-binding transcription factor activity
N7921_07765	COG1105	Belongs to the carbohydrate kinase PfkB family
N7921_07770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_07770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_07770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_07785	COG0488	(ABC) transporter
N7921_07790	COG2309	aminopeptidase activity
N7921_07800	COG1077	Cell shape determining protein MreB Mrl
N7921_07805	COG2002	toxin-antitoxin pair type II binding
N7921_07810	COG3852	Histidine kinase
N7921_07815	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
N7921_07815	COG2105	PFAM AIG2 family protein
N7921_07820	COG0569	domain protein
N7921_07825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N7921_07830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N7921_07835	COG5503	Protein of unknown function (DUF1447)
N7921_07840	COG0561	phosphatase activity
N7921_07845	COG0242	peptide deformylase activity
N7921_07860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7921_07865	COG0022	dehydrogenase e1 component
N7921_07870	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7921_07875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7921_07880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_07890	COG1982	Orn Lys Arg decarboxylase major
N7921_07895	COG4476	Belongs to the UPF0223 family
N7921_07900	COG4493	Belongs to the UPF0637 family
N7921_07910	COG0483	inositol monophosphate 1-phosphatase activity
N7921_07925	COG1595	DNA-templated transcription, initiation
N7921_07945	COG1217	gtp-binding protein TYPA
N7921_07955	COG4896	Protein conserved in bacteria
N7921_07965	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
N7921_07970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
N7921_07975	COG2066	Belongs to the glutaminase family
N7921_07980	COG4838	Belongs to the UPF0358 family
N7921_07985	COG0772	Belongs to the SEDS family
N7921_07990	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
N7921_07995	COG0415	Belongs to the DNA photolyase family
N7921_08000	COG1612	heme a metabolic process
N7921_08005	COG0109	protoheme IX farnesyltransferase activity
N7921_08010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7921_08010	COG2010	Cytochrome c
N7921_08015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7921_08020	COG1845	cytochrome c oxidase, subunit III
N7921_08025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N7921_08030	COG3336	cytochrome c oxidase
N7921_08040	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
N7921_08045	COG2340	Cysteine-rich secretory protein family
N7921_08065	COG3679	Belongs to the UPF0342 family
N7921_08070	COG4471	UPF0298 protein
N7921_08075	COG0742	ribosomal rna small subunit methyltransferase
N7921_08080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
N7921_08085	COG3314	Sporulation integral membrane protein YlbJ
N7921_08090	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7921_08095	COG3480	Lon protease (S16) C-terminal proteolytic domain
N7921_08105	COG1399	metal-binding, possibly nucleic acid-binding protein
N7921_08110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
N7921_08120	COG0454	-acetyltransferase
N7921_08125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
N7921_08130	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
N7921_08135	COG2001	Belongs to the MraZ family
N7921_08140	COG0275	rRNA processing
N7921_08145	COG4839	cell division protein FtsL
N7921_08150	COG0768	penicillin binding
N7921_08155	COG0768	penicillin binding
N7921_08160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N7921_08165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7921_08170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7921_08175	COG0772	Belongs to the SEDS family
N7921_08180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7921_08185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
N7921_08190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N7921_08195	COG3879	Bacterial protein of unknown function (DUF881)
N7921_08200	COG3879	Bacterial protein of unknown function (DUF881)
N7921_08205	COG3856	small basic protein
N7921_08210	COG0849	cell division
N7921_08215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N7921_08220	COG4412	M6 family metalloprotease domain protein
N7921_08220	COG1404	Belongs to the peptidase S8 family
N7921_08230	COG1191	sigma factor activity
N7921_08235	COG1191	sigma factor activity
N7921_08240	COG2390	Transcriptional regulator
N7921_08255	COG3730	PTS system glucitol sorbitol-specific
N7921_08260	COG3732	PTS system glucitol sorbitol-specific
N7921_08270	COG1119	ATPase activity
N7921_08275	COG1873	PFAM PRC-barrel domain
N7921_08280	COG1496	oxidoreductase activity
N7921_08285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
N7921_08290	COG1799	cell septum assembly
N7921_08295	COG0762	integral membrane protein
N7921_08300	COG2302	S4 RNA-binding domain
N7921_08305	COG3599	regulation of cell shape
N7921_08310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N7921_08315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7921_08320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
N7921_08325	COG0564	pseudouridine synthase activity
N7921_08330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
N7921_08335	COG2233	PERMEase
N7921_08340	COG0540	Belongs to the ATCase OTCase family
N7921_08345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
N7921_08350	COG0505	Belongs to the CarA family
N7921_08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
N7921_08360	COG0543	2 iron, 2 sulfur cluster binding
N7921_08365	COG0167	dihydroorotate dehydrogenase activity
N7921_08370	COG0284	orotidine-5'-phosphate decarboxylase activity
N7921_08375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
N7921_08385	COG0175	sulfate reduction
N7921_08390	COG0306	phosphate transporter
N7921_08395	COG2046	Belongs to the sulfate adenylyltransferase family
N7921_08400	COG0529	Catalyzes the synthesis of activated sulfate
N7921_08405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N7921_08410	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
N7921_08415	COG1648	precorrin-2 dehydrogenase activity
N7921_08425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
N7921_08430	COG1561	YicC-like family, N-terminal region
N7921_08435	COG2052	Domain of unknown function (DUF370)
N7921_08440	COG0194	GDP metabolic process
N7921_08445	COG1758	RNA polymerase activity
N7921_08450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N7921_08455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N7921_08460	COG0242	peptide deformylase activity
N7921_08465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
N7921_08470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
N7921_08470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7921_08475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
N7921_08480	COG0631	protein serine/threonine phosphatase activity
N7921_08485	COG0515	serine threonine protein kinase
N7921_08485	COG2815	serine threonine protein kinase
N7921_08490	COG1162	GTPase activity
N7921_08495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N7921_08500	COG1564	THIamine pyrophosphokinase
N7921_08510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
N7921_08515	COG1302	Protein conserved in bacteria
N7921_08520	COG1461	Dihydroxyacetone kinase
N7921_08525	COG1760	l-serine dehydratase
N7921_08530	COG1760	l-serine dehydratase
N7921_08535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N7921_08540	COG1349	DNA-binding transcription factor activity
N7921_08545	COG0416	fatty acid biosynthetic process
N7921_08550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N7921_08555	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_08560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7921_08570	COG1196	nuclear chromosome segregation
N7921_08575	COG0552	protein localization to endoplasmic reticulum
N7921_08580	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
N7921_08585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N7921_08590	COG0228	four-way junction DNA binding
N7921_08595	COG1837	Belongs to the UPF0109 family
N7921_08605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N7921_08610	COG0336	Belongs to the RNA methyltransferase TrmD family
N7921_08615	COG0335	large ribosomal subunit rRNA binding
N7921_08620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N7921_08625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7921_08635	COG2257	FlhB HrpN YscU SpaS Family
N7921_08640	COG0045	succinate-CoA ligase (ADP-forming) activity
N7921_08645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
N7921_08650	COG0758	DNA mediated transformation
N7921_08655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N7921_08660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
N7921_08665	COG4974	Belongs to the 'phage' integrase family
N7921_08670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
N7921_08675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
N7921_08680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N7921_08685	COG1815	bacterial-type flagellum-dependent cell motility
N7921_08690	COG1558	bacterial-type flagellum-dependent cell motility
N7921_08695	COG1677	Flagellar hook-basal body complex protein FliE
N7921_08700	COG1766	The M ring may be actively involved in energy transduction
N7921_08705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7921_08710	COG1317	bacterial-type flagellum organization
N7921_08715	COG1157	protein secretion by the type III secretion system
N7921_08720	COG2882	bacterial-type flagellum organization
N7921_08725	COG3334	PFAM MgtE intracellular
N7921_08730	COG3144	bacterial-type flagellum assembly
N7921_08735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
N7921_08740	COG4786	Flagellar basal body rod
N7921_08745	COG1582	Flagellar protein (FlbD)
N7921_08750	COG1580	Controls the rotational direction of flagella during chemotaxis
N7921_08755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7921_08760	COG1776	CheC inhibitor of MCP methylation
N7921_08760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
N7921_08765	COG2201	protein-glutamate methylesterase activity
N7921_08770	COG3190	flagellar
N7921_08775	COG1338	Plays a role in the flagellum-specific transport system
N7921_08780	COG1987	bacterial-type flagellum assembly
N7921_08785	COG1684	flagellar biosynthetic protein fliR
N7921_08790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7921_08795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
N7921_08800	COG1419	protein localization to endoplasmic reticulum
N7921_08805	COG0455	bacterial-type flagellum organization
N7921_08810	COG2201	protein-glutamate methylesterase activity
N7921_08815	COG0643	Histidine kinase
N7921_08815	COG2198	Histidine kinase
N7921_08820	COG0835	chemotaxis
N7921_08825	COG1776	CheC inhibitor of MCP methylation
N7921_08830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
N7921_08835	COG1191	sigma factor activity
N7921_08850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
N7921_08855	COG0528	UMP kinase activity
N7921_08860	COG0233	cytoplasmic translational termination
N7921_08865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N7921_08870	COG4589	Belongs to the CDS family
N7921_08875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
N7921_08880	COG0750	zinc metalloprotease
N7921_08885	COG0442	prolyl-tRNA aminoacylation
N7921_08890	COG2176	DNA-directed DNA polymerase activity
N7921_08905	COG3693	PFAM glycoside hydrolase, family 10
N7921_08925	COG1131	(ABC) transporter
N7921_08940	COG0779	Required for maturation of 30S ribosomal subunits
N7921_08945	COG0195	Participates in both transcription termination and antitermination
N7921_08950	COG2740	Nucleic-acid-binding protein implicated in transcription termination
N7921_08955	COG1358	cellular component organization or biogenesis
N7921_08960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
N7921_08965	COG1550	Protein conserved in bacteria
N7921_08970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
N7921_08975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N7921_08980	COG0196	riboflavin kinase activity
N7921_08985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
N7921_08990	COG1185	polyribonucleotide nucleotidyltransferase activity
N7921_08995	COG0726	polysaccharide deacetylase
N7921_09000	COG0612	Peptidase, M16
N7921_09005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7921_09015	COG1132	(ABC) transporter
N7921_09020	COG1132	(ABC) transporter
N7921_09055	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
N7921_09075	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_09080	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_09085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N7921_09090	COG1260	myo-inositol-1-phosphate synthase
N7921_09135	COG0367	asparagine synthase
N7921_09140	COG1873	PFAM PRC-barrel domain
N7921_09145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7921_09150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N7921_09155	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
N7921_09160	COG0527	aspartate kinase activity
N7921_09170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
N7921_09175	COG0740	serine-type endopeptidase activity
N7921_09185	COG1674	ftsk spoiiie
N7921_09185	COG4980	gas vesicle protein
N7921_09190	COG2188	Transcriptional regulator
N7921_09195	COG2814	Major facilitator Superfamily
N7921_09200	COG1033	growth of symbiont in host cell
N7921_09200	COG2409	Drug exporters of the RND superfamily
N7921_09205	COG0612	Peptidase, M16
N7921_09210	COG0612	Peptidase, M16
N7921_09220	COG1033	growth of symbiont in host cell
N7921_09220	COG2409	Drug exporters of the RND superfamily
N7921_09225	COG0300	oxidoreductase activity
N7921_09240	COG1426	Protein conserved in bacteria
N7921_09245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N7921_09250	COG1058	Belongs to the CinA family
N7921_09250	COG1546	Belongs to the CinA family
N7921_09255	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
N7921_09260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N7921_09265	COG1418	mRNA catabolic process
N7921_09270	COG1692	metallophosphoesterase
N7921_09275	COG2359	stage V sporulation protein S
N7921_09280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N7921_09285	COG1063	alcohol dehydrogenase
N7921_09290	COG0156	8-amino-7-oxononanoate synthase activity
N7921_09295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7921_09300	COG4550	Control of competence regulator ComK, YlbF/YmcA
N7921_09310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
N7921_09315	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N7921_09330	COG1329	Transcriptional regulator
N7921_09335	COG4195	phage-related replication protein
N7921_09340	COG0457	Tetratricopeptide repeat
N7921_09345	COG1404	Belongs to the peptidase S8 family
N7921_09350	COG4195	phage-related replication protein
N7921_09355	COG1764	response to oxidative stress
N7921_09360	COG2076	Multidrug Resistance protein
N7921_09385	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
N7921_09390	COG1923	regulation of RNA biosynthetic process
N7921_09405	COG1780	Probably involved in ribonucleotide reductase function
N7921_09410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7921_09415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N7921_09420	COG4112	unkown
N7921_09425	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7921_09430	COG0464	growth
N7921_09435	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N7921_09440	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
N7921_09445	COG0789	Transcriptional regulator
N7921_09450	COG0174	glutamine synthetase
N7921_09480	COG0457	Tetratricopeptide repeat
N7921_09490	COG5444	nuclease activity
N7921_09515	COG5646	InterPro IPR014922
N7921_09520	COG0457	Tetratricopeptide repeat
N7921_09530	COG3619	membrane
N7921_09535	COG1793	dna ligase
N7921_09535	COG3285	dna ligase
N7921_09540	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
N7921_09545	COG4876	unkown
N7921_09550	COG0346	lactoylglutathione lyase activity
N7921_09555	COG1959	2 iron, 2 sulfur cluster binding
N7921_09560	COG0702	epimerase
N7921_09565	COG0247	lactate metabolic process
N7921_09570	COG1139	Iron-sulfur cluster binding protein
N7921_09575	COG1556	Lactate utilization protein
N7921_09595	COG2323	membrane
N7921_09600	COG1309	transcriptional regulator
N7921_09605	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N7921_09605	COG2124	cytochrome p450
N7921_09610	COG3591	Belongs to the peptidase S1B family
N7921_09615	COG3209	COG3209 Rhs family protein
N7921_09620	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_09635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N7921_09640	COG1388	LysM domain
N7921_09645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N7921_09650	COG4224	UPF0291 protein
N7921_09655	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N7921_09665	COG3763	UPF0154 protein
N7921_09675	COG0785	Cytochrome C biogenesis protein
N7921_09680	COG4846	Membrane protein involved in cytochrome C biogenesis
N7921_09690	COG0071	Belongs to the small heat shock protein (HSP20) family
N7921_09705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N7921_09710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_09730	COG0824	Thioesterase
N7921_09740	COG4841	protein insertion into membrane
N7921_09745	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
N7921_09755	COG1832	CoA-binding protein
N7921_09760	COG0187	DNA topoisomerase II activity
N7921_09765	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
N7921_09785	COG0738	Major facilitator superfamily
N7921_09800	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_09805	COG1312	Catalyzes the dehydration of D-mannonate
N7921_09810	COG1802	Transcriptional regulator
N7921_09815	COG0673	inositol 2-dehydrogenase activity
N7921_09825	COG1904	glucuronate isomerase
N7921_09830	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7921_09835	COG1733	regulation of RNA biosynthetic process
N7921_09845	COG2197	response regulator
N7921_09850	COG4585	Histidine kinase
N7921_09855	COG2409	Drug exporters of the RND superfamily
N7921_09860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7921_09865	COG0251	oxidation-reduction process
N7921_09905	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N7921_09920	COG0583	DNA-binding transcription factor activity
N7921_09945	COG0657	acetylesterase activity
N7921_09950	COG0789	Transcriptional regulator
N7921_09960	COG2205	protein histidine kinase activity
N7921_09965	COG0745	RESPONSE REGULATOR receiver
N7921_09975	COG3507	Belongs to the glycosyl hydrolase 43 family
N7921_09980	COG1012	belongs to the aldehyde dehydrogenase family
N7921_09985	COG1486	melibiose metabolic process
N7921_09990	COG0395	ABC-type sugar transport system, permease component
N7921_09995	COG1175	transmembrane transport
N7921_10000	COG1653	transport
N7921_10005	COG1609	Transcriptional regulator
N7921_10010	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N7921_10025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_10035	COG0456	acetyltransferase
N7921_10040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7921_10070	COG5444	nuclease activity
N7921_10085	COG1846	Transcriptional regulator
N7921_10090	COG2814	Major facilitator Superfamily
N7921_10100	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_10100	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_10100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_10105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_10105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_10105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N7921_10110	COG1105	Belongs to the carbohydrate kinase PfkB family
N7921_10120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7921_10150	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N7921_10155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7921_10160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7921_10165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7921_10170	COG1024	Enoyl-CoA hydratase
N7921_10175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7921_10180	COG0511	ligase activity, forming carbon-carbon bonds
N7921_10185	COG0439	Biotin carboxylase
N7921_10190	COG0318	PFAM AMP-dependent synthetase and ligase
N7921_10195	COG1960	acyl-CoA dehydrogenase activity
N7921_10200	COG1649	PFAM Uncharacterised BCR, COG1649
N7921_10210	COG2365	Tyrosine phosphatase family
N7921_10215	COG1349	DNA-binding transcription factor activity
N7921_10225	COG3835	regulator
N7921_10230	COG0277	FAD linked oxidase domain protein
N7921_10235	COG0247	lactate metabolic process
N7921_10260	COG0166	Belongs to the GPI family
N7921_10265	COG2246	polysaccharide biosynthetic process
N7921_10270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7921_10275	COG0586	Pfam SNARE associated Golgi protein
N7921_10280	COG1587	Uroporphyrinogen-III synthase
N7921_10290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7921_10305	COG0534	Mate efflux family protein
N7921_10310	COG2027	D-alanyl-D-alanine carboxypeptidase
N7921_10315	COG4677	pectinesterase activity
N7921_10320	COG2323	membrane
N7921_10325	COG2146	nitrite reductase [NAD(P)H] activity
N7921_10330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7921_10335	COG0243	molybdopterin cofactor binding
N7921_10340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N7921_10345	COG2223	nitrite transmembrane transporter activity
N7921_10350	COG0493	'glutamate synthase
N7921_10355	COG0070	glutamate synthase
N7921_10355	COG0067	glutamate synthase
N7921_10355	COG0069	glutamate synthase activity
N7921_10360	COG0583	DNA-binding transcription factor activity
N7921_10370	COG1132	(ABC) transporter
N7921_10375	COG0789	Transcriptional regulator
N7921_10375	COG4978	Transcriptional regulator
N7921_10380	COG0454	-acetyltransferase
N7921_10385	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
N7921_10390	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
N7921_10405	COG0243	molybdopterin cofactor binding
N7921_10415	COG1070	Carbohydrate kinase
N7921_10420	COG2115	Belongs to the xylose isomerase family
N7921_10425	COG1940	carbohydrate kinase activity
N7921_10435	COG2211	Major facilitator Superfamily
N7921_10440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7921_10445	COG1994	Peptidase M50
N7921_10465	COG1309	transcriptional regulator
N7921_10470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7921_10475	COG3708	Transcriptional regulator
N7921_10480	COG2378	regulation of single-species biofilm formation
N7921_10490	COG0640	Transcriptional regulator
N7921_10495	COG0531	amino acid
N7921_10500	COG0741	lytic transglycosylase activity
N7921_10505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
N7921_10510	COG2079	MmgE PrpD family protein
N7921_10515	COG0372	Belongs to the citrate synthase family
N7921_10520	COG2322	membrane
N7921_10530	COG1388	LysM domain
N7921_10530	COG3584	3D domain protein
N7921_10535	COG0514	ATP-dependent DNA helicase (RecQ)
N7921_10545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7921_10570	COG1012	belongs to the aldehyde dehydrogenase family
N7921_10575	COG1657	PFAM Prenyltransferase squalene oxidase
N7921_10580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7921_10585	COG0385	Bile acid
N7921_10590	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7921_10595	COG0567	Dehydrogenase, E1 component
N7921_10600	COG4548	von Willebrand factor, type A
N7921_10605	COG0714	Associated with various cellular activities
N7921_10610	COG2032	superoxide dismutase activity
N7921_10615	COG0791	NLP P60 protein
N7921_10615	COG1388	LysM domain
N7921_10620	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
N7921_10630	COG0534	Mate efflux family protein
N7921_10635	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7921_10640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7921_10650	COG2962	Rard protein
N7921_10665	COG1733	regulation of RNA biosynthetic process
N7921_10670	COG0778	Nitroreductase
N7921_10680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7921_10685	COG0793	Belongs to the peptidase S41A family
N7921_10685	COG3409	Peptidoglycan-binding domain 1 protein
N7921_10690	COG2226	methyltransferase
N7921_10700	COG1876	peptidase activity
N7921_10705	COG0813	purine-nucleoside phosphorylase activity
N7921_10715	COG0671	phosphoesterase, PA-phosphatase related
N7921_10735	COG4479	Belongs to the UPF0346 family
N7921_10745	COG1509	lysine 2,3-aminomutase activity
N7921_10750	COG3829	transcription factor binding
N7921_10755	COG0463	Glycosyl transferase, family 2
N7921_10770	COG4641	Protein conserved in bacteria
N7921_10780	COG1086	Polysaccharide biosynthesis protein
N7921_10785	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7921_10790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
N7921_10795	COG1846	Transcriptional regulator
N7921_10815	COG4698	Protein conserved in bacteria
N7921_10820	COG2755	lipolytic protein G-D-S-L family
N7921_10825	COG1999	signal sequence binding
N7921_10840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N7921_10845	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
N7921_10850	COG1272	protein, Hemolysin III
N7921_10855	COG0204	Acyl-transferase
N7921_10860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
N7921_10865	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
N7921_10870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N7921_10880	COG2136	Putative SAM-dependent methyltransferase
N7921_10880	COG2521	methyltransferase
N7921_10890	COG0129	dihydroxy-acid dehydratase activity
N7921_10895	COG1413	lyase activity
N7921_10900	COG1418	mRNA catabolic process
N7921_10905	COG0386	Belongs to the glutathione peroxidase family
N7921_10910	COG2759	Belongs to the formate--tetrahydrofolate ligase family
N7921_10915	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
N7921_10920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
N7921_10930	COG1278	Cold shock
N7921_10945	COG0328	RNA-DNA hybrid ribonuclease activity
N7921_10950	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
N7921_10955	COG0328	RNA-DNA hybrid ribonuclease activity
N7921_10965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7921_10975	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N7921_10985	COG1755	Isoprenylcysteine carboxyl methyltransferase
N7921_10990	COG3424	synthase
N7921_10995	COG0726	polysaccharide deacetylase
N7921_11000	COG2233	PERMEase
N7921_11005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7921_11010	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
N7921_11015	COG1199	ATP-dependent helicase activity
N7921_11025	COG0116	Belongs to the methyltransferase superfamily
N7921_11035	COG3599	regulation of cell shape
N7921_11040	COG4474	Belongs to the UPF0398 family
N7921_11050	COG3359	exonuclease
N7921_11055	COG1111	helicase
N7921_11055	COG1205	dead DEAH box helicase
N7921_11060	COG1902	pentaerythritol trinitrate reductase activity
N7921_11065	COG2190	(PTS) system
N7921_11070	COG0071	Belongs to the small heat shock protein (HSP20) family
N7921_11100	COG3331	DNA recombination
N7921_11105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7921_11105	COG4499	WXG100 protein secretion system (Wss), protein YukC
N7921_11115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N7921_11120	COG3935	DnaD domain protein
N7921_11125	COG0017	Asparaginyl-tRNA synthetase
N7921_11130	COG5353	protein conserved in bacteria
N7921_11140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N7921_11140	COG1199	ATP-dependent helicase activity
N7921_11145	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
N7921_11150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
N7921_11155	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
N7921_11165	COG0617	tRNA 3'-terminal CCA addition
N7921_11170	COG0438	transferase activity, transferring glycosyl groups
N7921_11175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
N7921_11180	COG1803	Methylglyoxal synthase
N7921_11185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
N7921_11190	COG1694	Mazg nucleotide pyrophosphohydrolase
N7921_11195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7921_11205	COG4347	Protein of unknown function (DUF1405)
N7921_11210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7921_11210	COG2010	Cytochrome c
N7921_11215	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
N7921_11220	COG0723	plastoquinol--plastocyanin reductase activity
N7921_11230	COG5582	Belongs to the UPF0302 family
N7921_11235	COG0457	Tetratricopeptide repeat
N7921_11240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N7921_11245	COG0287	Prephenate dehydrogenase
N7921_11250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
N7921_11255	COG0159	tryptophan synthase activity
N7921_11260	COG0133	tryptophan synthase activity
N7921_11265	COG0135	phosphoribosylanthranilate isomerase activity
N7921_11270	COG0134	indole-3-glycerol-phosphate synthase activity
N7921_11285	COG4401	Chorismate mutase type I
N7921_11290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
N7921_11295	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
N7921_11300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
N7921_11305	COG0105	UTP biosynthetic process
N7921_11310	COG0142	geranyltranstransferase activity
N7921_11315	COG2226	methyltransferase
N7921_11320	COG0142	geranyltranstransferase activity
N7921_11330	COG0302	gtp cyclohydrolase
N7921_11335	COG0776	regulation of translation
N7921_11340	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
N7921_11355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
N7921_11360	COG1160	GTP binding
N7921_11385	COG1304	FMN binding
N7921_11390	COG0539	negative regulation of cytoplasmic translation
N7921_11395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
N7921_11405	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
N7921_11410	COG2959	enzyme of heme biosynthesis
N7921_11415	COG3409	Peptidoglycan-binding domain 1 protein
N7921_11415	COG3773	Cell wall hydrolase
N7921_11420	COG2339	peptidase activity
N7921_11425	COG0492	ferredoxin-NADP+ reductase activity
N7921_11430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7921_11435	COG4862	establishment of competence for transformation
N7921_11440	COG1408	metallophosphoesterase
N7921_11450	COG1388	LysM domain
N7921_11455	COG1266	CAAX protease self-immunity
N7921_11460	COG0514	ATP-dependent DNA helicase (RecQ)
N7921_11465	COG4955	Helix-turn-helix domain
N7921_11470	COG1141	Ferredoxin
N7921_11475	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
N7921_11480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N7921_11485	COG0791	NLP P60 protein
N7921_11485	COG1388	LysM domain
N7921_11495	COG1595	DNA-templated transcription, initiation
N7921_11500	COG5002	protein histidine kinase activity
N7921_11505	COG0745	RESPONSE REGULATOR receiver
N7921_11510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7921_11515	COG1333	cytochrome c biogenesis protein
N7921_11520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_11525	COG1187	pseudouridine synthase activity
N7921_11530	COG0700	Nucleoside recognition
N7921_11535	COG2715	membrane protein required for spore maturation
N7921_11540	COG1686	Belongs to the peptidase S11 family
N7921_11550	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N7921_11555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N7921_11565	COG1547	Domain of unknown function (DUF309)
N7921_11570	COG0456	acetyltransferase
N7921_11575	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
N7921_11585	COG0307	riboflavin synthase, alpha
N7921_11605	COG2814	Major facilitator Superfamily
N7921_11610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N7921_11615	COG4086	secreted protein
N7921_11620	COG0019	diaminopimelate decarboxylase activity
N7921_11625	COG0697	spore germination
N7921_11640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
N7921_11660	COG1191	sigma factor activity
N7921_11665	COG2172	sigma factor antagonist activity
N7921_11675	COG1686	Belongs to the peptidase S11 family
N7921_11680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
N7921_11685	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
N7921_11690	COG4974	Belongs to the 'phage' integrase family
N7921_11700	COG0735	belongs to the Fur family
N7921_11705	COG1300	Membrane
N7921_11710	COG1404	Belongs to the peptidase S8 family
N7921_11720	COG2153	protein acetylation
N7921_11725	COG1379	DNA repair
N7921_11730	COG0494	nUDIX hydrolase
N7921_11735	COG0667	Aldo Keto reductase
N7921_11745	COG1073	alpha beta
N7921_11750	COG0457	Tetratricopeptide repeat
N7921_11760	COG4918	Iron-sulphur cluster biosynthesis
N7921_11765	COG0456	acetyltransferase
N7921_11765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N7921_11770	COG0456	acetyltransferase
N7921_11780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7921_11790	COG2211	Major facilitator Superfamily
N7921_11795	COG1072	(Pantothenic acid kinase))
N7921_11800	COG0446	pyridine nucleotide-disulphide oxidoreductase
N7921_11805	COG0300	oxidoreductase activity
N7921_11810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7921_11815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7921_11825	COG4187	Peptidase family M20/M25/M40
N7921_11830	COG1902	pentaerythritol trinitrate reductase activity
N7921_11835	COG0596	Alpha beta hydrolase
N7921_11840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N7921_11850	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
N7921_11855	COG2188	Transcriptional regulator
N7921_11860	COG2723	6-phospho-beta-galactosidase activity
N7921_11865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7921_11870	COG1447	Phosphotransferase system cellobiose-specific component IIA
N7921_11875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7921_11880	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_11890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
N7921_11895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N7921_11910	COG0706	membrane insertase activity
N7921_11920	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7921_11925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N7921_11930	COG0346	lactoylglutathione lyase activity
N7921_11940	COG1376	ErfK ybiS ycfS ynhG family protein
N7921_11945	COG4129	membrane
N7921_11950	COG1126	abc transporter atp-binding protein
N7921_11955	COG0765	amino acid transport
N7921_11960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_11970	COG1597	lipid kinase activity
N7921_11980	COG0508	dehydrogenase complex catalyzes the overall conversion of
N7921_11985	COG0022	dehydrogenase e1 component
N7921_11990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N7921_11995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N7921_12000	COG3426	butyrate kinase activity
N7921_12005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7921_12010	COG0280	phosphate acetyltransferase
N7921_12015	COG3290	protein histidine kinase activity
N7921_12015	COG3829	transcription factor binding
N7921_12025	COG0584	glycerophosphoryl diester phosphodiesterase
N7921_12030	COG0457	Tetratricopeptide repeat
N7921_12035	COG0745	RESPONSE REGULATOR receiver
N7921_12040	COG0750	zinc metalloprotease
N7921_12045	COG0497	DNA recombination
N7921_12050	COG1438	arginine binding
N7921_12055	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
N7921_12060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
N7921_12065	COG0142	geranyltranstransferase activity
N7921_12070	COG1722	exodeoxyribonuclease VII activity
N7921_12075	COG1570	exodeoxyribonuclease VII activity
N7921_12080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
N7921_12085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
N7921_12090	COG1302	Protein conserved in bacteria
N7921_12095	COG0439	Biotin carboxylase
N7921_12100	COG0511	ligase activity, forming carbon-carbon bonds
N7921_12140	COG3854	ATPases associated with a variety of cellular activities
N7921_12150	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
N7921_12155	COG0006	proline dipeptidase activity
N7921_12160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
N7921_12170	COG3872	metal-dependent enzyme
N7921_12180	COG1752	Esterase of the alpha-beta hydrolase superfamily
N7921_12185	COG1321	iron dependent repressor
N7921_12190	COG0095	Lipoate-protein ligase
N7921_12195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7921_12200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7921_12205	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
N7921_12210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
N7921_12215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7921_12240	COG0681	Belongs to the peptidase S26 family
N7921_12275	COG4970	Tfp pilus assembly protein FimT
N7921_12280	COG4537	Required for transformation and DNA binding
N7921_12285	COG1459	type II secretion system
N7921_12290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N7921_12295	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_12305	COG1393	Belongs to the ArsC family
N7921_12315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7921_12325	COG0011	TIGRFAM Protein of
N7921_12330	COG2814	Major facilitator Superfamily
N7921_12335	COG2866	Carboxypeptidase
N7921_12340	COG1368	sulfuric ester hydrolase activity
N7921_12345	COG1940	carbohydrate kinase activity
N7921_12350	COG4483	Protein conserved in bacteria
N7921_12355	COG0457	Tetratricopeptide repeat
N7921_12355	COG0705	Rhomboid family
N7921_12375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N7921_12380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N7921_12390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7921_12395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7921_12400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N7921_12405	COG0581	inorganic phosphate transmembrane transporter activity
N7921_12410	COG0573	inorganic phosphate transmembrane transporter activity
N7921_12415	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N7921_12420	COG0768	penicillin binding
N7921_12425	COG0477	Major facilitator Superfamily
N7921_12430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N7921_12435	COG2839	Protein conserved in bacteria
N7921_12440	COG5521	maltodextrose utilization protein MalA
N7921_12445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
N7921_12450	COG1388	LysM domain
N7921_12455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
N7921_12460	COG4709	membrane
N7921_12465	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
N7921_12470	COG1940	carbohydrate kinase activity
N7921_12480	COG0735	belongs to the Fur family
N7921_12485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7921_12490	COG1121	(ABC) transporter
N7921_12495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7921_12505	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
N7921_12510	COG0513	Belongs to the DEAD box helicase family
N7921_12520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
N7921_12525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N7921_12530	COG2384	SAM-dependent methyltransferase
N7921_12535	COG2010	Cytochrome c
N7921_12540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
N7921_12545	COG0358	DNA primase activity
N7921_12550	COG1671	Belongs to the UPF0178 family
N7921_12555	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
N7921_12560	COG0517	IMP dehydrogenase activity
N7921_12565	COG0751	glycine-tRNA ligase activity
N7921_12570	COG0752	glycyl-tRNA synthetase alpha subunit
N7921_12575	COG1381	Involved in DNA repair and RecF pathway recombination
N7921_12585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N7921_12590	COG0295	cytidine deaminase activity
N7921_12595	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
N7921_12600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
N7921_12605	COG1480	7TM receptor with intracellular HD hydrolase
N7921_12610	COG1702	phosphate starvation-inducible protein PhoH
N7921_12615	COG0561	phosphatase activity
N7921_12630	COG4864	UPF0365 protein
N7921_12635	COG1030	water channel activity
N7921_12640	COG1610	YqeY-like protein
N7921_12650	COG1283	sodium-dependent phosphate transmembrane transporter activity
N7921_12655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
N7921_12660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N7921_12665	COG2264	protein methyltransferase activity
N7921_12670	COG0484	heat shock protein binding
N7921_12675	COG0443	Heat shock 70 kDa protein
N7921_12680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
N7921_12685	COG1420	regulation of RNA biosynthetic process
N7921_12690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N7921_12695	COG0481	GTPase activity
N7921_12705	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7921_12710	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
N7921_12715	COG0268	Binds directly to 16S ribosomal RNA
N7921_12720	COG1466	dna polymerase III delta subunit
N7921_12730	COG0658	competence protein
N7921_12730	COG2333	competence protein COMEC
N7921_12735	COG2131	deaminase
N7921_12740	COG1555	photosystem II stabilization
N7921_12745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
N7921_12750	COG2226	methyltransferase
N7921_12755	COG0799	negative regulation of ribosome biogenesis
N7921_12760	COG1713	HD superfamily hydrolase involved in NAD metabolism
N7921_12765	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
N7921_12770	COG1534	Rna-binding protein
N7921_12775	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
N7921_12780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
N7921_12785	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
N7921_12800	COG2755	lipolytic protein G-D-S-L family
N7921_12810	COG0457	Tetratricopeptide repeat
N7921_12835	COG2318	DinB family
N7921_12860	COG0726	polysaccharide deacetylase
N7921_12890	COG2160	L-arabinose isomerase activity
N7921_12905	COG1609	Transcriptional regulator
N7921_12915	COG1846	Transcriptional regulator
N7921_12925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
N7921_12930	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
N7921_12935	COG1733	regulation of RNA biosynthetic process
N7921_12955	COG2602	Beta-lactamase
N7921_12960	COG1960	acyl-CoA dehydrogenase activity
N7921_12965	COG1126	abc transporter atp-binding protein
N7921_12970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_12975	COG0765	amino acid transport
N7921_12985	COG3546	catalase activity
N7921_12990	COG1063	alcohol dehydrogenase
N7921_13000	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_13010	COG1115	amino acid carrier protein
N7921_13015	COG0583	DNA-binding transcription factor activity
N7921_13020	COG0842	Transport permease protein
N7921_13025	COG1511	domain protein
N7921_13025	COG0842	Transport permease protein
N7921_13030	COG1131	(ABC) transporter
N7921_13035	COG2226	methyltransferase
N7921_13040	COG1063	alcohol dehydrogenase
N7921_13045	COG2226	methyltransferase
N7921_13070	COG0626	cystathionine gamma-synthase activity
N7921_13075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7921_13080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N7921_13085	COG2226	methyltransferase
N7921_13100	COG0768	penicillin binding
N7921_13105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N7921_13115	COG0572	uridine kinase
N7921_13120	COG0826	peptidase U32
N7921_13125	COG0826	peptidase U32
N7921_13130	COG4122	O-methyltransferase activity
N7921_13135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
N7921_13140	COG0183	Belongs to the thiolase family
N7921_13145	COG0318	PFAM AMP-dependent synthetase and ligase
N7921_13150	COG1268	BioY protein
N7921_13155	COG3906	Belongs to the UPF0473 family
N7921_13160	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N7921_13165	COG4472	Bacterial protein of unknown function (DUF965)
N7921_13170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
N7921_13175	COG0628	permease
N7921_13180	COG1126	abc transporter atp-binding protein
N7921_13185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_13190	COG0765	amino acid transport
N7921_13195	COG0765	amino acid transport
N7921_13210	COG3881	PFAM PRC-barrel domain
N7921_13215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N7921_13220	COG0457	Tetratricopeptide repeat
N7921_13225	COG0482	sulfurtransferase activity
N7921_13230	COG1104	cysteine desulfurase activity
N7921_13235	COG1959	2 iron, 2 sulfur cluster binding
N7921_13240	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N7921_13245	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N7921_13260	COG0124	histidyl-tRNA synthetase
N7921_13270	COG3103	Sh3 type 3 domain protein
N7921_13270	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7921_13270	COG4991	sh3 domain protein
N7921_13275	COG1490	D-aminoacyl-tRNA deacylase activity
N7921_13280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N7921_13285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
N7921_13290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N7921_13290	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
N7921_13295	COG5416	Lipopolysaccharide assembly protein A domain
N7921_13300	COG0490	domain, Protein
N7921_13305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N7921_13305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N7921_13315	COG2244	polysaccharide biosynthetic process
N7921_13320	COG2323	membrane
N7921_13330	COG1862	Preprotein translocase
N7921_13335	COG0343	queuine tRNA-ribosyltransferase activity
N7921_13340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
N7921_13350	COG2255	four-way junction helicase activity
N7921_13355	COG0632	four-way junction helicase activity
N7921_13365	COG2112	serine threonine protein kinase
N7921_13380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
N7921_13395	COG1388	LysM domain
N7921_13400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N7921_13405	COG0157	Belongs to the NadC ModD family
N7921_13410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
N7921_13415	COG1104	cysteine desulfurase activity
N7921_13420	COG1827	regulation of RNA biosynthetic process
N7921_13425	COG0077	Prephenate dehydratase
N7921_13430	COG4492	Belongs to the UPF0735 family
N7921_13435	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
N7921_13440	COG3290	protein histidine kinase activity
N7921_13445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
N7921_13450	COG2868	ribosomal protein
N7921_13455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
N7921_13460	COG1994	Peptidase M50
N7921_13465	COG0739	heme binding
N7921_13470	COG2894	cell division
N7921_13475	COG0850	regulation of cytokinetic process
N7921_13480	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N7921_13490	COG1077	Cell shape determining protein MreB Mrl
N7921_13495	COG2003	Belongs to the UPF0758 family
N7921_13500	COG0424	maF-like protein
N7921_13510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
N7921_13515	COG0285	dihydrofolate synthase activity
N7921_13520	COG0525	valine-tRNA ligase activity
N7921_13530	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7921_13535	COG1388	LysM domain
N7921_13540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
N7921_13545	COG0113	porphobilinogen synthase activity
N7921_13550	COG1587	Uroporphyrinogen-III synthase
N7921_13555	COG0181	hydroxymethylbilane synthase activity
N7921_13560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
N7921_13565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
N7921_13575	COG0218	Necessary for normal cell division and for the maintenance of normal septation
N7921_13580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
N7921_13585	COG0470	DNA polymerase III
N7921_13585	COG1067	ATP-dependent peptidase activity
N7921_13590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
N7921_13595	COG0544	peptidyl-prolyl cis-trans isomerase activity
N7921_13600	COG0457	Tetratricopeptide repeat
N7921_13600	COG1477	protein flavinylation
N7921_13605	COG0066	3-isopropylmalate dehydratase activity
N7921_13610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
N7921_13615	COG0473	3-isopropylmalate dehydrogenase activity
N7921_13620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N7921_13625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
N7921_13630	COG0440	acetolactate synthase activity
N7921_13635	COG0028	Belongs to the TPP enzyme family
N7921_13640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7921_13645	COG2706	6-phosphogluconolactonase activity
N7921_13650	COG3339	Conserved Protein
N7921_13655	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
N7921_13660	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N7921_13665	COG1696	Membrane protein involved in D-alanine export
N7921_13680	COG0346	lactoylglutathione lyase activity
N7921_13715	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_13725	COG0622	Phosphoesterase
N7921_13730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
N7921_13735	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
N7921_13740	COG5401	PFAM Sporulation and spore germination
N7921_13745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N7921_13750	COG1846	Transcriptional regulator
N7921_13755	COG2197	response regulator
N7921_13760	COG2851	Citrate transporter
N7921_13765	COG0583	DNA-binding transcription factor activity
N7921_13770	COG2828	Protein conserved in bacteria
N7921_13780	COG0824	Thioesterase
N7921_13785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N7921_13790	COG1053	succinate dehydrogenase
N7921_13795	COG2009	succinate dehydrogenase
N7921_13800	COG1719	4-vinyl reductase, 4VR
N7921_13805	COG0527	aspartate kinase activity
N7921_13810	COG0322	excinuclease ABC activity
N7921_13815	COG3118	belongs to the thioredoxin family
N7921_13820	COG3534	alpha-L-arabinofuranosidase
N7921_13825	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
N7921_13830	COG2086	electron transfer activity
N7921_13835	COG1024	Enoyl-CoA hydratase
N7921_13840	COG1309	transcriptional regulator
N7921_13845	COG0318	PFAM AMP-dependent synthetase and ligase
N7921_13855	COG3766	membrane
N7921_13860	COG1193	negative regulation of DNA recombination
N7921_13865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N7921_13865	COG1796	DNA polymerase
N7921_13870	COG1286	toxin biosynthetic process
N7921_13875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
N7921_13880	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N7921_13885	COG0072	phenylalanine-tRNA ligase activity
N7921_13885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7921_13890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
N7921_13895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N7921_13905	COG1966	Carbon starvation protein
N7921_13910	COG1363	Peptidase, m42
N7921_13920	COG3326	Membrane
N7921_13925	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
N7921_13930	COG0291	Belongs to the bacterial ribosomal protein bL35 family
N7921_13935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
N7921_13940	COG1346	cytolysis
N7921_13950	COG3279	Response regulator of the LytR AlgR family
N7921_13955	COG3275	phosphorelay sensor kinase activity
N7921_13960	COG1011	Hydrolase
N7921_13965	COG0840	transmembrane signaling receptor activity
N7921_13975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
N7921_13985	COG0398	Pfam SNARE associated Golgi protein
N7921_13990	COG1484	DNA-dependent DNA replication
N7921_13995	COG3611	Membrane attachment protein
N7921_14000	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
N7921_14010	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
N7921_14015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N7921_14020	COG0237	dephospho-CoA kinase activity
N7921_14025	COG1971	Probably functions as a manganese efflux pump
N7921_14030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
N7921_14035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7921_14035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
N7921_14040	COG5002	protein histidine kinase activity
N7921_14045	COG0745	RESPONSE REGULATOR receiver
N7921_14050	COG0039	L-malate dehydrogenase activity
N7921_14055	COG0538	isocitrate dehydrogenase activity
N7921_14060	COG0372	Belongs to the citrate synthase family
N7921_14065	COG2707	UPF0756 membrane protein
N7921_14070	COG0628	permease
N7921_14075	COG3030	protein affecting phage T7 exclusion by the F plasmid
N7921_14085	COG0205	6-phosphofructokinase activity
N7921_14090	COG0825	malonyl-CoA metabolic process
N7921_14095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
N7921_14100	COG0281	malic enzyme
N7921_14105	COG0587	DNA-directed DNA polymerase activity
N7921_14125	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
N7921_14135	COG4109	DRTGG domain
N7921_14140	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
N7921_14145	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_14155	COG0165	Argininosuccinate lyase
N7921_14160	COG0137	argininosuccinate synthase activity
N7921_14165	COG0521	Mo-molybdopterin cofactor biosynthetic process
N7921_14170	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N7921_14175	COG0827	DNA restriction-modification system
N7921_14180	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
N7921_14185	COG3874	Sporulation protein YtfJ
N7921_14195	COG1714	RDD family
N7921_14200	COG0616	signal peptide processing
N7921_14205	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N7921_14215	COG3239	Fatty acid desaturase
N7921_14220	COG4585	Histidine kinase
N7921_14225	COG2197	response regulator
N7921_14230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_14235	COG0745	RESPONSE REGULATOR receiver
N7921_14240	COG0642	Histidine kinase
N7921_14245	COG0772	Belongs to the SEDS family
N7921_14250	COG1695	Transcriptional regulator
N7921_14255	COG1136	(ABC) transporter
N7921_14260	COG0577	efflux transmembrane transporter activity
N7921_14265	COG0402	S-adenosylhomocysteine deaminase activity
N7921_14270	COG2249	NAD(P)H dehydrogenase (quinone) activity
N7921_14280	COG1279	arginine transmembrane transporter activity
N7921_14285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7921_14295	COG0301	tRNA thio-modification
N7921_14300	COG1104	cysteine desulfurase activity
N7921_14305	COG1114	Component of the transport system for branched-chain amino acids
N7921_14310	COG1114	Component of the transport system for branched-chain amino acids
N7921_14315	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
N7921_14320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
N7921_14325	COG1309	transcriptional regulator
N7921_14330	COG1956	GAF domain-containing protein
N7921_14335	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
N7921_14350	COG1335	isochorismatase
N7921_14360	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
N7921_14365	COG2329	Antibiotic biosynthesis monooxygenase
N7921_14370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N7921_14375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N7921_14380	COG0454	-acetyltransferase
N7921_14385	COG0517	IMP dehydrogenase activity
N7921_14390	COG0123	including yeast histone deacetylase and acetoin utilization protein
N7921_14395	COG1609	Transcriptional regulator
N7921_14400	COG1605	Chorismate mutase
N7921_14400	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
N7921_14405	COG3118	belongs to the thioredoxin family
N7921_14410	COG4980	gas vesicle protein
N7921_14415	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
N7921_14420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N7921_14425	COG1674	ftsk spoiiie
N7921_14430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N7921_14435	COG4848	Belongs to the UPF0354 family
N7921_14440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_14455	COG1363	Peptidase, m42
N7921_14460	COG5584	Small secreted protein
N7921_14465	COG0281	malic enzyme
N7921_14470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N7921_14475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N7921_14485	COG0510	thiamine kinase activity
N7921_14490	COG1597	lipid kinase activity
N7921_14500	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
N7921_14505	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N7921_14510	COG3340	Belongs to the peptidase S51 family
N7921_14515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
N7921_14520	COG2252	PERMEase
N7921_14525	COG1349	DNA-binding transcription factor activity
N7921_14530	COG1187	pseudouridine synthase activity
N7921_14535	COG2244	polysaccharide biosynthetic process
N7921_14540	COG2081	HI0933 family
N7921_14550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N7921_14555	COG3196	Protein conserved in bacteria
N7921_14565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
N7921_14570	COG5578	integral membrane protein
N7921_14575	COG0673	inositol 2-dehydrogenase activity
N7921_14580	COG1653	transport
N7921_14585	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
N7921_14590	COG4209	transmembrane transport
N7921_14595	COG2207	Transcriptional regulator
N7921_14600	COG1733	regulation of RNA biosynthetic process
N7921_14605	COG2814	Major facilitator Superfamily
N7921_14610	COG0656	L-ascorbic acid biosynthetic process
N7921_14615	COG1653	transport
N7921_14620	COG0395	ABC-type sugar transport system, permease component
N7921_14625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7921_14630	COG1073	alpha beta
N7921_14635	COG0495	leucyl-tRNA aminoacylation
N7921_14645	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_14645	COG2202	Pas domain
N7921_14650	COG2433	Pfam Transposase IS66
N7921_14655	COG0577	efflux transmembrane transporter activity
N7921_14660	COG1136	(ABC) transporter
N7921_14670	COG1131	(ABC) transporter
N7921_14675	COG1725	Transcriptional regulator
N7921_14690	COG1242	4 iron, 4 sulfur cluster binding
N7921_14695	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
N7921_14705	COG2267	carboxylic ester hydrolase activity
N7921_14710	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N7921_14715	COG0367	asparagine synthase
N7921_14720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
N7921_14725	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
N7921_14735	COG1506	peptidase
N7921_14740	COG1233	COG1233 Phytoene dehydrogenase and related
N7921_14760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N7921_14765	COG1116	anion transmembrane transporter activity
N7921_14770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N7921_14775	COG0494	nUDIX hydrolase
N7921_14780	COG2310	stress, protein
N7921_14795	COG4824	toxin secretion phage lysis holin
N7921_14805	COG0783	Belongs to the Dps family
N7921_14820	COG1854	S-ribosylhomocysteine lyase activity
N7921_14825	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
N7921_14830	COG0288	reversible hydration of carbon dioxide
N7921_14835	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7921_14835	COG3443	Belongs to the bacterial solute-binding protein 9 family
N7921_14840	COG0254	rRNA binding
N7921_14845	COG1271	oxidase subunit
N7921_14850	COG1294	oxidase, subunit
N7921_14865	COG4948	Mandelate Racemase Muconate Lactonizing
N7921_14870	COG0318	PFAM AMP-dependent synthetase and ligase
N7921_14875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
N7921_14880	COG0596	Alpha beta hydrolase
N7921_14885	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
N7921_14890	COG1169	isochorismate synthase
N7921_14895	COG1575	Belongs to the MenA family. Type 1 subfamily
N7921_14900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N7921_15030	COG3859	Proton-coupled thiamine transporter YuaJ
N7921_15035	COG1247	-acetyltransferase
N7921_15040	COG3339	Conserved Protein
N7921_15045	COG0772	Belongs to the SEDS family
N7921_15050	COG0772	Belongs to the SEDS family
N7921_15055	COG2268	Band 7 protein
N7921_15060	COG1585	Membrane protein implicated in regulation of membrane protease activity
N7921_15065	COG2318	DinB family
N7921_15070	COG1454	alcohol dehydrogenase
N7921_15075	COG1012	belongs to the aldehyde dehydrogenase family
N7921_15080	COG1510	regulation of RNA biosynthetic process
N7921_15095	COG5632	N-Acetylmuramoyl-L-alanine amidase
N7921_15095	COG3409	Peptidoglycan-binding domain 1 protein
N7921_15140	COG3778	Protein conserved in bacteria
N7921_15145	COG3299	homolog of phage Mu protein gp47
N7921_15150	COG3628	GPW Gp25 family protein
N7921_15160	COG4193	domain, Protein
N7921_15165	COG1652	LysM domain
N7921_15170	COG5280	Phage tail tape measure protein TP901
N7921_15170	COG3953	SLT domain
N7921_15220	COG4653	Phage capsid family
N7921_15225	COG0338	D12 class N6 adenine-specific DNA methyltransferase
N7921_15230	COG5518	Phage portal protein
N7921_15235	COG1783	phage Terminase large subunit
N7921_15240	COG5484	DNA packaging
N7921_15245	COG1595	DNA-templated transcription, initiation
N7921_15255	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
N7921_15275	COG1396	sequence-specific DNA binding
N7921_15285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
N7921_15300	COG0628	permease
N7921_15310	COG0673	inositol 2-dehydrogenase activity
N7921_15315	COG0693	protein deglycase activity
N7921_15320	COG0840	transmembrane signaling receptor activity
N7921_15325	COG0840	transmembrane signaling receptor activity
N7921_15330	COG0840	transmembrane signaling receptor activity
N7921_15335	COG0840	transmembrane signaling receptor activity
N7921_15350	COG2070	2-Nitropropane dioxygenase
N7921_15355	COG0432	Pfam Uncharacterised protein family UPF0047
N7921_15360	COG1253	flavin adenine dinucleotide binding
N7921_15365	COG2738	Putative neutral zinc metallopeptidase
N7921_15375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N7921_15390	COG0166	Belongs to the GPI family
N7921_15395	COG1979	alcohol dehydrogenase
N7921_15400	COG1979	alcohol dehydrogenase
N7921_15405	COG2155	Conserved Protein
N7921_15410	COG1098	S1 RNA binding domain
N7921_15415	COG0436	Aminotransferase
N7921_15420	COG1522	sequence-specific DNA binding
N7921_15425	COG2267	carboxylic ester hydrolase activity
N7921_15435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
N7921_15440	COG2205	protein histidine kinase activity
N7921_15455	COG5018	Exonuclease
N7921_15460	COG2814	Major facilitator Superfamily
N7921_15465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7921_15470	COG3011	Protein conserved in bacteria
N7921_15480	COG3290	protein histidine kinase activity
N7921_15485	COG4565	transcriptional regulatory protein
N7921_15490	COG1744	ABC transporter substrate-binding protein PnrA-like
N7921_15495	COG3845	ABC transporter
N7921_15500	COG4603	Belongs to the binding-protein-dependent transport system permease family
N7921_15505	COG1079	Belongs to the binding-protein-dependent transport system permease family
N7921_15510	COG3493	citrate carrier protein
N7921_15520	COG2111	Na H antiporter
N7921_15520	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N7921_15525	COG2111	Na H antiporter
N7921_15530	COG1006	Multisubunit Na H antiporter MnhC subunit
N7921_15535	COG0651	ATP synthesis coupled electron transport
N7921_15540	COG1863	multisubunit Na H antiporter MnhE subunit
N7921_15545	COG2212	antiporter activity
N7921_15550	COG1320	monovalent cation:proton antiporter activity
N7921_15555	COG2050	protein possibly involved in aromatic compounds catabolism
N7921_15560	COG2197	response regulator
N7921_15565	COG4585	Histidine kinase
N7921_15575	COG0142	geranyltranstransferase activity
N7921_15590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
N7921_15595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
N7921_15600	COG1335	isochorismatase
N7921_15605	COG5506	Protein of unknown function (DUF1694)
N7921_15625	COG0628	permease
N7921_15640	COG1418	mRNA catabolic process
N7921_15645	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_15655	COG1511	domain protein
N7921_15660	COG1674	ftsk spoiiie
N7921_15660	COG0433	COG0433 Predicted ATPase
N7921_15665	COG4499	WXG100 protein secretion system (Wss), protein YukC
N7921_15670	COG5417	Belongs to the EsaB family
N7921_15675	COG4842	Belongs to the WXG100 family
N7921_15680	COG2508	Transcriptional regulator
N7921_15680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N7921_15685	COG0686	Belongs to the AlaDH PNT family
N7921_15690	COG1268	BioY protein
N7921_15695	COG4326	sporulation control protein
N7921_15700	COG2056	Na+-H+ antiporter family
N7921_15705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
N7921_15710	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
N7921_15715	COG3584	3D domain protein
N7921_15730	COG1252	NADH dehydrogenase
N7921_15735	COG0492	ferredoxin-NADP+ reductase activity
N7921_15745	COG0789	Transcriptional regulator
N7921_15750	COG5504	Zn-dependent protease
N7921_15755	COG0316	Belongs to the HesB IscA family
N7921_15760	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
N7921_15765	COG4844	belongs to the
N7921_15770	COG1252	NADH dehydrogenase
N7921_15780	COG4837	Protein of unknown function (DUF1462)
N7921_15790	COG1506	peptidase
N7921_15790	COG4946	Tricorn protease homolog
N7921_15790	COG0823	Involved in the tonB-independent uptake of proteins
N7921_15795	COG0083	homoserine kinase activity
N7921_15800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N7921_15805	COG0460	homoserine dehydrogenase
N7921_15810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7921_15815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N7921_15820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N7921_15825	COG0647	UMP catabolic process
N7921_15830	COG2445	Protein of unknown function DUF86
N7921_15835	COG4470	Protein conserved in bacteria
N7921_15845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N7921_15850	COG0739	heme binding
N7921_15860	COG3377	Domain of unknown function (DUF1805)
N7921_15865	COG0737	Belongs to the 5'-nucleotidase family
N7921_15870	COG1801	Protein of unknown function DUF72
N7921_15875	COG2508	Transcriptional regulator
N7921_15880	COG2140	Oxalate decarboxylase
N7921_15890	COG2814	Major facilitator Superfamily
N7921_15895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N7921_15900	COG2356	endonuclease I
N7921_15910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_15915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_15920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_15940	COG0642	Histidine kinase
N7921_15940	COG5002	protein histidine kinase activity
N7921_15945	COG0745	RESPONSE REGULATOR receiver
N7921_15950	COG2311	Membrane
N7921_15960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N7921_15965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7921_15970	COG1309	transcriptional regulator
N7921_15975	COG0719	Fe-S assembly protein
N7921_15980	COG0822	iron-sulfur transferase activity
N7921_15985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N7921_15990	COG0719	Fe-S assembly protein
N7921_15995	COG0396	ATPase activity
N7921_16005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N7921_16010	COG1464	Belongs to the NlpA lipoprotein family
N7921_16015	COG2011	ABC-type metal ion transport system permease component
N7921_16020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N7921_16030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_16035	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
N7921_16045	COG0509	glycine decarboxylation via glycine cleavage system
N7921_16050	COG1393	Belongs to the ArsC family
N7921_16055	COG1960	acyl-CoA dehydrogenase activity
N7921_16060	COG0183	Belongs to the thiolase family
N7921_16065	COG1024	Enoyl-CoA hydratase
N7921_16065	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7921_16080	COG5577	PFAM Coat F domain
N7921_16090	COG1120	ATPase activity
N7921_16100	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_16105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7921_16110	COG0745	RESPONSE REGULATOR receiver
N7921_16115	COG2205	protein histidine kinase activity
N7921_16115	COG2770	Histidine kinase
N7921_16125	COG1309	transcriptional regulator
N7921_16135	COG0114	fumarate hydratase activity
N7921_16145	COG0697	spore germination
N7921_16150	COG0814	amino acid
N7921_16165	COG2197	response regulator
N7921_16170	COG4585	Histidine kinase
N7921_16175	COG4758	membrane
N7921_16185	COG1842	Phage shock protein A
N7921_16190	COG4758	membrane
N7921_16195	COG2096	Adenosyltransferase
N7921_16205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
N7921_16215	COG2204	response regulator
N7921_16230	COG1454	alcohol dehydrogenase
N7921_16235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N7921_16245	COG1120	ATPase activity
N7921_16250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_16255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_16265	COG2721	sulfolactate sulfo-lyase activity
N7921_16270	COG0246	Mannitol dehydrogenase
N7921_16275	COG1609	Transcriptional regulator
N7921_16280	COG1904	glucuronate isomerase
N7921_16285	COG2205	protein histidine kinase activity
N7921_16290	COG0745	RESPONSE REGULATOR receiver
N7921_16295	COG1120	ATPase activity
N7921_16300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_16305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_16310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_16315	COG0531	amino acid
N7921_16330	COG1988	membrane-bound metal-dependent
N7921_16335	COG1368	sulfuric ester hydrolase activity
N7921_16340	COG0725	ABC transporter, periplasmic molybdate-binding protein
N7921_16345	COG4149	molybdate abc transporter
N7921_16350	COG0656	L-ascorbic acid biosynthetic process
N7921_16355	COG1940	carbohydrate kinase activity
N7921_16360	COG0025	NhaP-type Na H and K H
N7921_16365	COG2860	membrane
N7921_16370	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
N7921_16375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N7921_16380	COG2217	Heavy metal translocating P-type atpase
N7921_16385	COG1121	(ABC) transporter
N7921_16390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N7921_16395	COG0803	Belongs to the bacterial solute-binding protein 9 family
N7921_16405	COG3226	Transcriptional regulator
N7921_16410	COG0784	Response regulator, receiver
N7921_16415	COG4191	Histidine kinase
N7921_16420	COG1027	Aspartate ammonia-lyase
N7921_16435	COG2217	Heavy metal translocating P-type atpase
N7921_16440	COG2608	mercury ion transmembrane transporter activity
N7921_16445	COG1937	Protein conserved in bacteria
N7921_16480	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
N7921_16485	COG0557	exoribonuclease II activity
N7921_16490	COG1647	Serine aminopeptidase, S33
N7921_16495	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
N7921_16500	COG2002	toxin-antitoxin pair type II binding
N7921_16505	COG1476	TRANSCRIPTIONal
N7921_16510	COG1396	sequence-specific DNA binding
N7921_16515	COG1396	sequence-specific DNA binding
N7921_16520	COG1733	regulation of RNA biosynthetic process
N7921_16525	COG1174	glycine betaine transport
N7921_16530	COG1732	Glycine betaine
N7921_16535	COG1174	glycine betaine transport
N7921_16540	COG0517	IMP dehydrogenase activity
N7921_16540	COG1125	glycine betaine transport
N7921_16545	COG1510	regulation of RNA biosynthetic process
N7921_16550	COG2095	MarC family integral membrane protein
N7921_16560	COG0456	acetyltransferase
N7921_16580	COG1122	ATPase activity
N7921_16590	COG0148	phosphopyruvate hydratase activity
N7921_16595	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N7921_16600	COG0149	triose-phosphate isomerase activity
N7921_16605	COG0126	phosphoglycerate kinase activity
N7921_16610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N7921_16615	COG2390	Transcriptional regulator
N7921_16620	COG0833	amino acid
N7921_16625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N7921_16630	COG3829	transcription factor binding
N7921_16635	COG2186	Transcriptional regulator
N7921_16640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
N7921_16650	COG0534	Mate efflux family protein
N7921_16655	COG4608	Belongs to the ABC transporter superfamily
N7921_16660	COG0444	Belongs to the ABC transporter superfamily
N7921_16665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N7921_16670	COG0601	transmembrane transport
N7921_16675	COG0747	negative chemotaxis
N7921_16680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7921_16685	COG0110	maltose O-acetyltransferase activity
N7921_16690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N7921_16695	COG2244	polysaccharide biosynthetic process
N7921_16700	COG5039	Polysaccharide pyruvyl transferase
N7921_16705	COG1216	Glycosyl transferase, family 2
N7921_16715	COG0438	transferase activity, transferring glycosyl groups
N7921_16720	COG1215	transferase activity, transferring glycosyl groups
N7921_16725	COG0438	transferase activity, transferring glycosyl groups
N7921_16730	COG1086	Polysaccharide biosynthesis protein
N7921_16735	COG0489	protein tyrosine kinase activity
N7921_16740	COG3944	biosynthesis protein
N7921_16745	COG1396	sequence-specific DNA binding
N7921_16755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_16760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_16765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_16770	COG0726	polysaccharide deacetylase
N7921_16775	COG0488	(ABC) transporter
N7921_16780	COG1819	glycosyl
N7921_16805	COG0740	serine-type endopeptidase activity
N7921_16810	COG1611	Belongs to the LOG family
N7921_16815	COG1694	Mazg nucleotide pyrophosphohydrolase
N7921_16820	COG0659	secondary active sulfate transmembrane transporter activity
N7921_16825	COG0288	reversible hydration of carbon dioxide
N7921_16830	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
N7921_16840	COG2162	N-hydroxyarylamine O-acetyltransferase activity
N7921_16845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_16850	COG1481	regulation of sporulation
N7921_16855	COG0391	Required for morphogenesis under gluconeogenic growth conditions
N7921_16860	COG1660	Displays ATPase and GTPase activities
N7921_16865	COG1051	belongs to the nudix hydrolase family
N7921_16870	COG0492	ferredoxin-NADP+ reductase activity
N7921_16875	COG0791	NLP P60 protein
N7921_16875	COG3883	PFAM NLP P60 protein
N7921_16880	COG0457	Tetratricopeptide repeat
N7921_16885	COG0140	phosphoribosyl-ATP diphosphatase activity
N7921_16885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N7921_16890	COG0107	imidazoleglycerol-phosphate synthase activity
N7921_16895	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
N7921_16900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N7921_16905	COG0131	Imidazoleglycerol-phosphate dehydratase
N7921_16910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N7921_16915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N7921_16920	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
N7921_16925	COG4990	cell redox homeostasis
N7921_16935	COG2910	NAD(P)H-binding
N7921_16940	COG1959	2 iron, 2 sulfur cluster binding
N7921_16945	COG0110	maltose O-acetyltransferase activity
N7921_16950	COG0546	phosphoglycolate phosphatase activity
N7921_16955	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
N7921_16960	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
N7921_16965	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
N7921_16970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
N7921_16975	COG0363	glucosamine-6-phosphate deaminase activity
N7921_16980	COG2188	Transcriptional regulator
N7921_16985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N7921_16990	COG1950	PFAM Membrane protein of
N7921_16995	COG1983	PspC domain protein
N7921_17000	COG3595	metallopeptidase activity
N7921_17015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N7921_17025	COG4897	Protein conserved in bacteria
N7921_17030	COG0574	Belongs to the PEP-utilizing enzyme family
N7921_17030	COG3848	Pyruvate phosphate dikinase
N7921_17035	COG1309	transcriptional regulator
N7921_17040	COG2814	Major facilitator Superfamily
N7921_17050	COG0745	RESPONSE REGULATOR receiver
N7921_17055	COG5002	protein histidine kinase activity
N7921_17060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
N7921_17065	COG0463	Glycosyl transferase, family 2
N7921_17070	COG1113	amino acid transport
N7921_17075	COG0778	Nitroreductase
N7921_17080	COG1733	regulation of RNA biosynthetic process
N7921_17085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7921_17095	COG3409	Peptidoglycan-binding domain 1 protein
N7921_17095	COG0793	Belongs to the peptidase S41A family
N7921_17100	COG0730	response to heat
N7921_17105	COG0791	NLP P60 protein
N7921_17105	COG3883	PFAM NLP P60 protein
N7921_17110	COG2177	Part of the ABC transporter FtsEX involved in
N7921_17115	COG2884	Cell division ATP-binding protein ftsE
N7921_17120	COG2010	Cytochrome c
N7921_17125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
N7921_17145	COG0653	protein targeting
N7921_17150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
N7921_17155	COG0840	transmembrane signaling receptor activity
N7921_17170	COG1516	flagellar protein fliS
N7921_17175	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
N7921_17180	COG1334	flagellar protein FlaG
N7921_17185	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
N7921_17190	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
N7921_17200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
N7921_17205	COG1256	bacterial-type flagellum assembly
N7921_17205	COG4786	Flagellar basal body rod
N7921_17210	COG3418	PFAM FlgN family protein
N7921_17225	COG1040	competence protein
N7921_17235	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
N7921_17240	COG1307	EDD domain protein, DegV family
N7921_17245	COG2197	response regulator
N7921_17250	COG4585	Histidine kinase
N7921_17255	COG1739	Uncharacterized protein family UPF0029
N7921_17260	COG1316	TRANSCRIPTIONal
N7921_17265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
N7921_17270	COG0438	transferase activity, transferring glycosyl groups
N7921_17275	COG1215	transferase activity, transferring glycosyl groups
N7921_17280	COG3206	protein involved in exopolysaccharide biosynthesis
N7921_17285	COG3307	-O-antigen
N7921_17290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N7921_17295	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7921_17300	COG0438	transferase activity, transferring glycosyl groups
N7921_17300	COG0297	glycogen (starch) synthase activity
N7921_17305	COG2244	polysaccharide biosynthetic process
N7921_17320	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7921_17320	COG2247	cell wall binding repeat
N7921_17325	COG2247	cell wall binding repeat
N7921_17325	COG0860	N-Acetylmuramoyl-L-alanine amidase
N7921_17330	COG2247	cell wall binding repeat
N7921_17330	COG2385	sporulation resulting in formation of a cellular spore
N7921_17340	COG1316	TRANSCRIPTIONal
N7921_17345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
N7921_17350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N7921_17355	COG1134	teichoic acid transport
N7921_17360	COG1682	transport, permease protein
N7921_17365	COG1216	Glycosyl transferase, family 2
N7921_17375	COG1181	Belongs to the D-alanine--D-alanine ligase family
N7921_17380	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7921_17390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N7921_17395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7921_17405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
N7921_17410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
N7921_17415	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7921_17420	COG4193	domain, Protein
N7921_17425	COG0463	Glycosyl transferase, family 2
N7921_17425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7921_17430	COG1482	cell wall glycoprotein biosynthetic process
N7921_17440	COG1175	transmembrane transport
N7921_17445	COG1653	transport
N7921_17450	COG2197	response regulator
N7921_17455	COG2972	Histidine kinase
N7921_17465	COG0454	-acetyltransferase
N7921_17470	COG0800	Aldolase
N7921_17475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7921_17480	COG1609	Transcriptional regulator
N7921_17485	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
N7921_17490	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_17495	COG0697	spore germination
N7921_17500	COG0814	amino acid
N7921_17515	COG2814	Major facilitator Superfamily
N7921_17520	COG1316	TRANSCRIPTIONal
N7921_17525	COG0561	phosphatase activity
N7921_17530	COG0791	NLP P60 protein
N7921_17540	COG2843	Capsule synthesis protein
N7921_17550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
N7921_17555	COG0697	spore germination
N7921_17570	COG1609	Transcriptional regulator
N7921_17575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N7921_17580	COG1869	D-ribose catabolic process
N7921_17585	COG1129	ABC transporter
N7921_17590	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7921_17595	COG1879	ABC-type sugar transport system periplasmic component
N7921_17600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N7921_17605	COG0583	DNA-binding transcription factor activity
N7921_17610	COG0028	Belongs to the TPP enzyme family
N7921_17615	COG3527	Alpha-acetolactate decarboxylase
N7921_17620	COG1522	sequence-specific DNA binding
N7921_17625	COG2059	Chromate
N7921_17630	COG2059	Chromate
N7921_17635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
N7921_17645	COG4715	Zinc finger, swim domain protein
N7921_17650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N7921_17655	COG2202	Pas domain
N7921_17655	COG1366	Belongs to the anti-sigma-factor antagonist family
N7921_17660	COG0561	phosphatase activity
N7921_17675	COG1970	mechanosensitive ion channel activity
N7921_17680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
N7921_17685	COG0457	Tetratricopeptide repeat
N7921_17690	COG4786	Flagellar basal body rod
N7921_17695	COG4786	Flagellar basal body rod
N7921_17700	COG1077	Cell shape determining protein MreB Mrl
N7921_17705	COG1609	Transcriptional regulator
N7921_17710	COG1846	Transcriptional regulator
N7921_17715	COG2814	Major facilitator Superfamily
N7921_17720	COG0671	phosphoesterase, PA-phosphatase related
N7921_17725	COG0477	Major facilitator Superfamily
N7921_17730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_17735	COG0765	amino acid transport
N7921_17745	COG0004	ammonium transporteR
N7921_17750	COG0347	Belongs to the P(II) protein family
N7921_17755	COG0739	heme binding
N7921_17760	COG1247	-acetyltransferase
N7921_17800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
N7921_17805	COG0523	cobalamin synthesis protein
N7921_17810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
N7921_17815	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N7921_17820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N7921_17825	COG2223	nitrite transmembrane transporter activity
N7921_17830	COG0243	molybdopterin cofactor binding
N7921_17835	COG2304	oxidoreductase activity
N7921_17840	COG2304	oxidoreductase activity
N7921_17845	COG2385	sporulation resulting in formation of a cellular spore
N7921_17850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7921_17860	COG4836	Membrane
N7921_17870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
N7921_17875	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
N7921_17880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
N7921_17885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
N7921_17890	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7921_17895	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
N7921_17900	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
N7921_17905	COG0356	it plays a direct role in the translocation of protons across the membrane
N7921_17915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
N7921_17920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
N7921_17925	COG4475	Protein of unknown function (DUF436)
N7921_17930	COG0698	ribose 5-phosphate isomerase
N7921_17935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N7921_17940	COG1971	Probably functions as a manganese efflux pump
N7921_17945	COG0009	L-threonylcarbamoyladenylate synthase
N7921_17950	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
N7921_17965	COG2890	protein-(glutamine-N5) methyltransferase activity
N7921_17970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
N7921_17975	COG0789	Transcriptional regulator
N7921_17980	COG0679	Auxin Efflux Carrier
N7921_17985	COG0281	malic enzyme
N7921_17990	COG1435	thymidine kinase activity
N7921_17995	COG0254	rRNA binding
N7921_18000	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
N7921_18005	COG1494	fructose-1,6-bisphosphatase
N7921_18010	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N7921_18015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N7921_18020	COG0191	fructose-bisphosphate aldolase activity
N7921_18025	COG2204	response regulator
N7921_18030	COG4821	SIS domain
N7921_18035	COG0504	CTP synthase activity
N7921_18040	COG3343	RNA polymerase activity
N7921_18050	COG1960	acyl-CoA dehydrogenase activity
N7921_18055	COG1960	acyl-CoA dehydrogenase activity
N7921_18060	COG1250	3-hydroxyacyl-CoA dehydrogenase
N7921_18065	COG0183	Belongs to the thiolase family
N7921_18070	COG0247	lactate metabolic process
N7921_18070	COG2181	nitrate reductase activity
N7921_18075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7921_18080	COG4294	response to UV
N7921_18090	COG1619	proteins homologs of microcin C7 resistance protein MccF
N7921_18095	COG1132	(ABC) transporter
N7921_18100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N7921_18105	COG1619	proteins homologs of microcin C7 resistance protein MccF
N7921_18110	COG0018	arginyl-trna synthetase
N7921_18115	COG4506	Protein conserved in bacteria
N7921_18125	COG0010	Belongs to the arginase family
N7921_18130	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
N7921_18135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N7921_18145	COG1994	Peptidase M50
N7921_18150	COG1942	4-Oxalocrotonate Tautomerase
N7921_18160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7921_18165	COG0583	DNA-binding transcription factor activity
N7921_18170	COG0431	NADPH-dependent FMN reductase
N7921_18175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7921_18180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N7921_18185	COG0454	-acetyltransferase
N7921_18190	COG0765	amino acid transport
N7921_18195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_18205	COG1126	abc transporter atp-binding protein
N7921_18210	COG3465	dGTPase activity
N7921_18215	COG1078	dGTPase activity
N7921_18220	COG4844	belongs to the
N7921_18300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N7921_18310	COG0280	phosphate acetyltransferase
N7921_18320	COG1073	alpha beta
N7921_18325	COG1522	sequence-specific DNA binding
N7921_18330	COG2814	Major facilitator Superfamily
N7921_18335	COG0077	Prephenate dehydratase
N7921_18345	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_18350	COG0151	Belongs to the GarS family
N7921_18355	COG0436	Aminotransferase
N7921_18360	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_18365	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
N7921_18370	COG1091	dTDP-4-dehydrorhamnose reductase activity
N7921_18375	COG1088	dTDP-glucose 4,6-dehydratase activity
N7921_18380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
N7921_18385	COG3980	spore coat polysaccharide biosynthesis protein
N7921_18390	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
N7921_18395	COG2089	acid synthase
N7921_18400	COG0456	acetyltransferase
N7921_18405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N7921_18410	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
N7921_18415	COG0463	Glycosyl transferase, family 2
N7921_18435	COG2363	Small membrane protein
N7921_18440	COG2233	PERMEase
N7921_18450	COG1012	belongs to the aldehyde dehydrogenase family
N7921_18455	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
N7921_18460	COG1216	Glycosyl transferase, family 2
N7921_18470	COG0351	phosphomethylpyrimidine kinase
N7921_18490	COG3964	amidohydrolase
N7921_18500	COG1621	beta-fructofuranosidase activity
N7921_18505	COG1263	PTS System
N7921_18505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_18510	COG3711	transcriptional antiterminator
N7921_18520	COG1404	Belongs to the peptidase S8 family
N7921_18525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N7921_18530	COG0778	Nitroreductase
N7921_18535	COG0772	Belongs to the SEDS family
N7921_18545	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N7921_18550	COG1845	cytochrome c oxidase, subunit III
N7921_18555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N7921_18560	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N7921_18570	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
N7921_18575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N7921_18580	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
N7921_18595	COG2246	polysaccharide biosynthetic process
N7921_18615	COG3162	membrane
N7921_18620	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N7921_18635	COG0352	thiamine-phosphate diphosphorylase activity
N7921_18640	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
N7921_18645	COG0583	DNA-binding transcription factor activity
N7921_18650	COG1380	Effector of murein hydrolase LrgA
N7921_18655	COG1346	cytolysis
N7921_18660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
N7921_18665	COG0346	lactoylglutathione lyase activity
N7921_18675	COG0765	amino acid transport
N7921_18680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N7921_18685	COG0457	Tetratricopeptide repeat
N7921_18695	COG2357	RelA SpoT domain protein
N7921_18700	COG1172	Belongs to the binding-protein-dependent transport system permease family
N7921_18705	COG1129	ABC transporter
N7921_18715	COG3420	alginic acid biosynthetic process
N7921_18720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N7921_18730	COG1486	melibiose metabolic process
N7921_18735	COG1447	Phosphotransferase system cellobiose-specific component IIA
N7921_18740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7921_18745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7921_18750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_18750	COG3711	transcriptional antiterminator
N7921_18770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N7921_18785	COG1595	DNA-templated transcription, initiation
N7921_18795	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
N7921_18800	COG4988	ABC transporter
N7921_18805	COG1294	oxidase, subunit
N7921_18810	COG1271	oxidase subunit
N7921_18825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N7921_18835	COG4509	Sortase family
N7921_18860	COG5386	Cell surface protein
N7921_18865	COG5386	Cell surface protein
N7921_18870	COG1733	regulation of RNA biosynthetic process
N7921_18875	COG2514	catechol 2,3-dioxygenase activity
N7921_18880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7921_18880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N7921_18885	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7921_18885	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N7921_18895	COG0726	polysaccharide deacetylase
N7921_18900	COG1447	Phosphotransferase system cellobiose-specific component IIA
N7921_18905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7921_18910	COG2723	6-phospho-beta-galactosidase activity
N7921_18915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
N7921_18920	COG3711	transcriptional antiterminator
N7921_18920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
N7921_18945	COG1757	Na H antiporter
N7921_18950	COG1027	Aspartate ammonia-lyase
N7921_18955	COG0252	asparaginase activity
N7921_18960	COG1396	sequence-specific DNA binding
N7921_18985	COG4842	Belongs to the WXG100 family
N7921_18990	COG2195	Cleaves the N-terminal amino acid of tripeptides
N7921_19005	COG1737	Transcriptional regulator
N7921_19010	COG2084	Dehydrogenase
N7921_19020	COG2610	gluconate transmembrane transporter activity
N7921_19025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
N7921_19030	COG2723	6-phospho-beta-galactosidase activity
N7921_19035	COG2190	(PTS) system
N7921_19035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_19035	COG1263	PTS System
N7921_19040	COG3711	transcriptional antiterminator
N7921_19045	COG3878	Protein conserved in bacteria
N7921_19055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N7921_19060	COG1122	ATPase activity
N7921_19065	COG4721	ABC-type cobalt transport system, permease component
N7921_19070	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N7921_19105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N7921_19110	COG0778	Nitroreductase
N7921_19120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
N7921_19125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
N7921_19130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
N7921_19135	COG2390	Transcriptional regulator
N7921_19145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
N7921_19145	COG2755	lipolytic protein G-D-S-L family
N7921_19165	COG0561	phosphatase activity
N7921_19170	COG0789	Transcriptional regulator
N7921_19175	COG0673	inositol 2-dehydrogenase activity
N7921_19180	COG0840	transmembrane signaling receptor activity
N7921_19185	COG1113	amino acid transport
N7921_19190	COG4335	DNA alkylation repair
N7921_19200	COG1070	Carbohydrate kinase
N7921_19205	COG1737	Transcriptional regulator
N7921_19240	COG0583	DNA-binding transcription factor activity
N7921_19245	COG1609	Transcriptional regulator
N7921_19250	COG2182	Extracellular solute-binding protein
N7921_19255	COG1175	transmembrane transport
N7921_19260	COG3833	ABC-type maltose transport systems, permease component
N7921_19270	COG1874	Beta-galactosidase
N7921_19275	COG2851	Citrate transporter
N7921_19285	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
N7921_19290	COG1131	(ABC) transporter
N7921_19295	COG2824	Alkylphosphonate utilization operon protein PhnA
N7921_19300	COG1929	Belongs to the glycerate kinase type-1 family
N7921_19305	COG2610	gluconate transmembrane transporter activity
N7921_19310	COG3835	regulator
N7921_19315	COG1309	transcriptional regulator
N7921_19320	COG2814	Major facilitator Superfamily
N7921_19330	COG0577	efflux transmembrane transporter activity
N7921_19330	COG1136	(ABC) transporter
N7921_19340	COG0457	Tetratricopeptide repeat
N7921_19345	COG3711	transcriptional antiterminator
N7921_19350	COG2723	6-phospho-beta-galactosidase activity
N7921_19355	COG2190	(PTS) system
N7921_19355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_19355	COG1263	PTS System
N7921_19390	COG1113	amino acid transport
N7921_19395	COG1609	Transcriptional regulator
N7921_19400	COG2814	Major facilitator Superfamily
N7921_19410	COG2814	Major facilitator Superfamily
N7921_19415	COG2723	6-phospho-beta-galactosidase activity
N7921_19425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
N7921_19425	COG2190	(PTS) system
N7921_19425	COG1263	PTS System
N7921_19440	COG1012	belongs to the aldehyde dehydrogenase family
N7921_19460	COG0163	prenyltransferase activity
N7921_19465	COG0583	DNA-binding transcription factor activity
N7921_19470	COG2723	6-phospho-beta-galactosidase activity
N7921_19480	COG2188	Transcriptional regulator
N7921_19495	COG0384	phenazine biosynthesis protein PhzF
N7921_19500	COG0583	DNA-binding transcription factor activity
N7921_19525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N7921_19535	COG2814	Major facilitator Superfamily
N7921_19540	COG0640	Transcriptional regulator
N7921_19580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
N7921_19590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
N7921_19600	COG4720	Psort location CytoplasmicMembrane, score
N7921_19620	COG0456	acetyltransferase
N7921_19625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N7921_19630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
N7921_19635	COG4853	Protein conserved in bacteria
N7921_19640	COG4863	YycH protein
N7921_19645	COG5002	protein histidine kinase activity
N7921_19650	COG0745	RESPONSE REGULATOR receiver
N7921_19675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
N7921_19685	COG2311	Membrane
N7921_19690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N7921_19695	COG1309	transcriptional regulator
N7921_19700	COG2124	cytochrome p450
N7921_19705	COG0346	lactoylglutathione lyase activity
N7921_19710	COG0305	Participates in initiation and elongation during chromosome replication
N7921_19735	COG2819	hydrolase of the alpha beta superfamily
N7921_19740	COG1028	Short-chain dehydrogenase reductase Sdr
N7921_19745	COG1169	isochorismate synthase
N7921_19750	COG1021	2,3-dihydroxybenzoate-AMP ligase
N7921_19755	COG1535	isochorismatase
N7921_19755	COG3433	isochorismatase activity
N7921_19760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N7921_19765	COG3251	PFAM MbtH domain protein
N7921_19770	COG2207	Transcriptional regulator
N7921_19770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_19775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
N7921_19780	COG2819	hydrolase of the alpha beta superfamily
N7921_19785	COG3093	addiction module antidote protein HigA
N7921_19790	COG2807	transmembrane transport
N7921_19795	COG0359	binds to the 23S rRNA
N7921_19800	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
N7921_19805	COG4241	membrane
N7921_19810	COG1227	inorganic diphosphatase activity
N7921_19820	COG1595	DNA-templated transcription, initiation
N7921_19830	COG0753	catalase activity
N7921_19835	COG0655	NAD(P)H dehydrogenase (quinone) activity
N7921_19840	COG0400	carboxylic ester hydrolase activity
N7921_19845	COG0346	lactoylglutathione lyase activity
N7921_19850	COG1174	glycine betaine transport
N7921_19855	COG0517	IMP dehydrogenase activity
N7921_19855	COG1125	glycine betaine transport
N7921_19860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
N7921_19865	COG0629	single-stranded DNA binding
N7921_19870	COG0360	Binds together with S18 to 16S ribosomal RNA
N7921_19875	COG0012	GTP binding
N7921_19880	COG4481	Protein conserved in bacteria
N7921_19895	COG3949	Membrane
N7921_19905	COG1475	DNA binding
N7921_19910	COG1192	Involved in chromosome partitioning
N7921_19915	COG1475	DNA binding
N7921_19920	COG0357	Ribosomal RNA small subunit methyltransferase G
N7921_19925	COG0445	tRNA wobble uridine modification
N7921_19930	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
N7921_19935	COG1847	R3H domain protein
N7921_19940	COG0706	membrane insertase activity
N7921_19945	COG0594	ribonuclease P activity
N7921_19950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
N7921_19985	COG0457	Tetratricopeptide repeat