locus-tag	class	description
BRL64_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BRL64_00010	COG0592	DNA-directed DNA polymerase activity
BRL64_00015	COG2501	S4 domain
BRL64_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BRL64_00030	COG0187	DNA topoisomerase II activity
BRL64_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BRL64_00070	COG0516	GMP reductase activity
BRL64_00070	COG0517	IMP dehydrogenase activity
BRL64_00075	COG1686	Belongs to the peptidase S11 family
BRL64_00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRL64_00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BRL64_00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BRL64_00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BRL64_00100	COG0840	transmembrane signaling receptor activity
BRL64_00110	COG1428	Deoxynucleoside kinase
BRL64_00115	COG1428	Deoxynucleoside kinase
BRL64_00120	COG3858	chitin binding
BRL64_00120	COG1388	LysM domain
BRL64_00125	COG1335	isochorismatase
BRL64_00130	COG0590	tRNA wobble adenosine to inosine editing
BRL64_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BRL64_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BRL64_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BRL64_00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BRL64_00200	COG3853	Toxic anion resistance protein (TelA)
BRL64_00205	COG1982	Orn Lys Arg decarboxylase major
BRL64_00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BRL64_00215	COG3870	Protein conserved in bacteria
BRL64_00220	COG1728	Protein conserved in bacteria
BRL64_00225	COG0470	DNA polymerase III
BRL64_00230	COG1774	PSP1 C-terminal conserved region
BRL64_00235	COG4467	Involved in initiation control of chromosome replication
BRL64_00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BRL64_00245	COG2827	Endonuclease containing a URI domain
BRL64_00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BRL64_00255	COG2002	toxin-antitoxin pair type II binding
BRL64_00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRL64_00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRL64_00265	COG0084	hydrolase, TatD family'
BRL64_00270	COG3584	3D domain protein
BRL64_00270	COG3583	domain protein
BRL64_00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BRL64_00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BRL64_00290	COG4466	Protein conserved in bacteria
BRL64_00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BRL64_00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BRL64_00310	COG0251	oxidation-reduction process
BRL64_00315	COG2088	sporulation resulting in formation of a cellular spore
BRL64_00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BRL64_00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BRL64_00335	COG0193	aminoacyl-tRNA hydrolase activity
BRL64_00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BRL64_00350	COG2002	toxin-antitoxin pair type II binding
BRL64_00355	COG2244	polysaccharide biosynthetic process
BRL64_00360	COG3956	TIGRFAM MazG family protein
BRL64_00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BRL64_00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BRL64_00385	COG1098	S1 RNA binding domain
BRL64_00400	COG2208	phosphoserine phosphatase activity
BRL64_00405	COG2304	oxidoreductase activity
BRL64_00410	COG0515	serine threonine protein kinase
BRL64_00415	COG0037	tRNA processing
BRL64_00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BRL64_00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BRL64_00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BRL64_00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BRL64_00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BRL64_00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BRL64_00455	COG0512	Glutamine amidotransferase of anthranilate synthase
BRL64_00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BRL64_00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BRL64_00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BRL64_00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BRL64_00480	COG1396	sequence-specific DNA binding
BRL64_00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BRL64_00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BRL64_00595	COG4463	regulation of RNA biosynthetic process
BRL64_00600	COG3880	PFAM UvrB UvrC protein
BRL64_00605	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BRL64_00610	COG0542	response to heat
BRL64_00615	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BRL64_00620	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BRL64_00625	COG4956	integral membrane protein (PIN domain superfamily)
BRL64_00630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BRL64_00635	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BRL64_00640	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BRL64_00645	COG1045	serine acetyltransferase
BRL64_00650	COG0215	cysteine-tRNA ligase activity
BRL64_00655	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BRL64_00660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRL64_00665	COG3688	RNA-binding protein containing a PIN domain
BRL64_00670	COG1595	DNA-templated transcription, initiation
BRL64_00675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BRL64_00680	COG0250	Participates in transcription elongation, termination and antitermination
BRL64_00685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BRL64_00690	COG0081	regulation of translation
BRL64_00695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BRL64_00700	COG0222	ribosome binding
BRL64_00705	COG2813	Specifically methylates the guanine in position
BRL64_00710	COG0085	RNA polymerase activity
BRL64_00715	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BRL64_00720	COG1358	cellular component organization or biogenesis
BRL64_00725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BRL64_00730	COG0049	tRNA binding
BRL64_00735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BRL64_00740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BRL64_00745	COG0596	Alpha beta hydrolase
BRL64_00750	COG0051	transcription antitermination factor activity, RNA binding
BRL64_00755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BRL64_00760	COG0088	Forms part of the polypeptide exit tunnel
BRL64_00765	COG0089	rRNA binding
BRL64_00770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BRL64_00775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BRL64_00780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BRL64_00785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BRL64_00790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BRL64_00795	COG0255	Belongs to the universal ribosomal protein uL29 family
BRL64_00800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BRL64_00805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BRL64_00810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BRL64_00815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BRL64_00820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BRL64_00825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BRL64_00830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BRL64_00835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BRL64_00840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BRL64_00845	COG1841	ribosomal large subunit assembly
BRL64_00850	COG0200	Binds to the 23S rRNA
BRL64_00855	COG0201	protein transport
BRL64_00860	COG0563	adenylate kinase activity
BRL64_00865	COG0024	Methionine aminopeptidase
BRL64_00870	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BRL64_00875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BRL64_00880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BRL64_00885	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BRL64_00890	COG0202	RNA polymerase activity
BRL64_00895	COG0203	ribosomal protein L17
BRL64_00900	COG1122	ATPase activity
BRL64_00905	COG1122	ATPase activity
BRL64_00910	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BRL64_00915	COG0101	tRNA pseudouridine synthase activity
BRL64_00920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BRL64_00925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BRL64_00940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRL64_00960	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRL64_00965	COG0489	protein tyrosine kinase activity
BRL64_00975	COG2194	sulfuric ester hydrolase activity
BRL64_00980	COG0726	polysaccharide deacetylase
BRL64_01020	COG0659	secondary active sulfate transmembrane transporter activity
BRL64_01025	COG0385	Bile acid
BRL64_01030	COG3876	Protein conserved in bacteria
BRL64_01035	COG1472	Belongs to the glycosyl hydrolase 3 family
BRL64_01040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BRL64_01045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_01045	COG1263	PTS System
BRL64_01050	COG1737	Transcriptional regulator
BRL64_01055	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BRL64_01090	COG1595	DNA-templated transcription, initiation
BRL64_01095	COG5662	AntiSigma factor
BRL64_01100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BRL64_01105	COG4856	YbbR-like protein
BRL64_01110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BRL64_01115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BRL64_01135	COG1131	(ABC) transporter
BRL64_01150	COG1131	(ABC) transporter
BRL64_01165	COG3402	PFAM membrane-flanked domain
BRL64_01170	COG1131	(ABC) transporter
BRL64_01215	COG2311	Membrane
BRL64_01235	COG1113	amino acid transport
BRL64_01240	COG0584	glycerophosphoryl diester phosphodiesterase
BRL64_01245	COG2271	Major facilitator Superfamily
BRL64_01255	COG1331	Highly conserved protein containing a thioredoxin domain
BRL64_01265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRL64_01275	COG1937	Protein conserved in bacteria
BRL64_01280	COG2210	Belongs to the sulfur carrier protein TusA family
BRL64_01290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRL64_01290	COG0425	Belongs to the sulfur carrier protein TusA family
BRL64_01295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRL64_01295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRL64_01300	COG0425	Belongs to the sulfur carrier protein TusA family
BRL64_01305	COG0730	response to heat
BRL64_01310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BRL64_01315	COG2814	Major facilitator Superfamily
BRL64_01325	COG1846	Transcriptional regulator
BRL64_01335	COG1683	Conserved Protein
BRL64_01345	COG0656	L-ascorbic acid biosynthetic process
BRL64_01350	COG0371	Dehydrogenase
BRL64_01360	COG0531	amino acid
BRL64_01370	COG3711	transcriptional antiterminator
BRL64_01375	COG1263	PTS System
BRL64_01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_01375	COG2190	(PTS) system
BRL64_01380	COG2723	6-phospho-beta-galactosidase activity
BRL64_01400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_01400	COG3711	transcriptional antiterminator
BRL64_01405	COG1940	carbohydrate kinase activity
BRL64_01410	COG0383	alpha-mannosidase activity
BRL64_01415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_01420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_01425	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_01425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_01430	COG1404	Belongs to the peptidase S8 family
BRL64_01445	COG0833	amino acid
BRL64_01450	COG2040	homocysteine
BRL64_01455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BRL64_01460	COG1695	Transcriptional regulator
BRL64_01470	COG2814	Major facilitator Superfamily
BRL64_01490	COG1404	Belongs to the peptidase S8 family
BRL64_01500	COG1309	transcriptional regulator
BRL64_01505	COG1917	Cupin 2, conserved barrel domain protein
BRL64_01510	COG1063	alcohol dehydrogenase
BRL64_01515	COG1846	Transcriptional regulator
BRL64_01520	COG0318	PFAM AMP-dependent synthetase and ligase
BRL64_01525	COG0531	amino acid
BRL64_01535	COG0596	Alpha beta hydrolase
BRL64_01540	COG1115	amino acid carrier protein
BRL64_01545	COG2066	Belongs to the glutaminase family
BRL64_01550	COG4191	Histidine kinase
BRL64_01555	COG0784	Response regulator, receiver
BRL64_01560	COG1405	negative regulation of cell septum assembly
BRL64_01560	COG3012	SEC-C Motif Domain Protein
BRL64_01570	COG2197	response regulator
BRL64_01575	COG4585	Histidine kinase
BRL64_01585	COG0667	Aldo Keto reductase
BRL64_01590	COG3290	protein histidine kinase activity
BRL64_01595	COG3279	Response regulator of the LytR AlgR family
BRL64_01600	COG4555	ABC transporter
BRL64_01605	COG1668	transmembrane transport
BRL64_01625	COG3773	Cell wall hydrolase
BRL64_01630	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_01640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRL64_01645	COG2310	stress, protein
BRL64_01650	COG2310	stress, protein
BRL64_01655	COG2310	stress, protein
BRL64_01660	COG0861	Integral membrane protein TerC family
BRL64_01690	COG3853	Toxic anion resistance protein (TelA)
BRL64_01695	COG0517	IMP dehydrogenase activity
BRL64_01695	COG4175	Glycine betaine
BRL64_01700	COG4176	ABC-type proline glycine betaine transport system permease component
BRL64_01705	COG2113	Glycine betaine
BRL64_01710	COG0596	Alpha beta hydrolase
BRL64_01720	COG1473	amidohydrolase
BRL64_01725	COG1288	antiporter activity
BRL64_01730	COG0039	L-malate dehydrogenase activity
BRL64_01735	COG1620	l-lactate permease
BRL64_01740	COG1609	Transcriptional regulator
BRL64_01745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BRL64_01750	COG0561	phosphatase activity
BRL64_01755	COG0673	inositol 2-dehydrogenase activity
BRL64_01760	COG0738	Major facilitator superfamily
BRL64_01765	COG1280	lysine exporter protein (LysE YggA)
BRL64_01775	COG3403	YqcI/YcgG family
BRL64_01780	COG1113	amino acid transport
BRL64_01785	COG3665	Urea carboxylase-associated protein
BRL64_01790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BRL64_01800	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_01805	COG0710	3-dehydroquinate dehydratase activity
BRL64_01810	COG0028	Belongs to the TPP enzyme family
BRL64_01820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BRL64_01825	COG2271	Major facilitator Superfamily
BRL64_01835	COG1414	Transcriptional regulator
BRL64_01840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BRL64_01845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRL64_01850	COG1609	Transcriptional regulator
BRL64_01855	COG0477	Major facilitator Superfamily
BRL64_01860	COG2226	methyltransferase
BRL64_01865	COG0583	DNA-binding transcription factor activity
BRL64_01870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BRL64_01875	COG3458	cephalosporin-C deacetylase activity
BRL64_01885	COG3541	Predicted nucleotidyltransferase
BRL64_01890	COG0506	proline dehydrogenase activity
BRL64_01895	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_01900	COG2508	Transcriptional regulator
BRL64_01905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BRL64_01910	COG0765	amino acid transport
BRL64_01915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL64_01925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BRL64_01930	COG1522	sequence-specific DNA binding
BRL64_01935	COG2746	aminoglycoside 3-N-acetyltransferase activity
BRL64_01945	COG0840	transmembrane signaling receptor activity
BRL64_01945	COG3290	protein histidine kinase activity
BRL64_01950	COG3209	COG3209 Rhs family protein
BRL64_01970	COG3842	ATPase activity
BRL64_01975	COG1176	ABC-type spermidine putrescine transport system, permease component I
BRL64_01985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BRL64_01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BRL64_01995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BRL64_02010	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BRL64_02025	COG4555	ABC transporter
BRL64_02040	COG0697	spore germination
BRL64_02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRL64_02060	COG2364	Membrane
BRL64_02065	COG0737	Belongs to the 5'-nucleotidase family
BRL64_02070	COG3764	Sortase (surface protein transpeptidase)
BRL64_02075	COG2002	toxin-antitoxin pair type II binding
BRL64_02080	COG1126	abc transporter atp-binding protein
BRL64_02085	COG0765	amino acid transport
BRL64_02090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL64_02100	COG0833	amino acid
BRL64_02105	COG3104	oligopeptide transport
BRL64_02110	COG5434	Belongs to the glycosyl hydrolase 28 family
BRL64_02125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL64_02130	COG0765	amino acid transport
BRL64_02135	COG1126	abc transporter atp-binding protein
BRL64_02145	COG2079	MmgE PrpD family protein
BRL64_02150	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_02155	COG0527	aspartate kinase activity
BRL64_02160	COG2814	Major facilitator Superfamily
BRL64_02165	COG1309	transcriptional regulator
BRL64_02175	COG0640	Transcriptional regulator
BRL64_02180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRL64_02185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BRL64_02190	COG0531	amino acid
BRL64_02195	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_02200	COG2249	NAD(P)H dehydrogenase (quinone) activity
BRL64_02205	COG4549	nuclear export factor GLE1
BRL64_02210	COG1276	copper resistance
BRL64_02210	COG2372	response to copper ion
BRL64_02215	COG2213	PTS system mannitol-specific
BRL64_02220	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_02225	COG0246	Mannitol dehydrogenase
BRL64_02230	COG0840	transmembrane signaling receptor activity
BRL64_02250	COG0346	lactoylglutathione lyase activity
BRL64_02260	COG0561	phosphatase activity
BRL64_02265	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BRL64_02270	COG1914	H( )-stimulated, divalent metal cation uptake system
BRL64_02275	COG4336	lyase activity
BRL64_02280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BRL64_02285	COG1984	allophanate hydrolase subunit 2
BRL64_02290	COG1414	Transcriptional regulator
BRL64_02295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BRL64_02300	COG2755	lipolytic protein G-D-S-L family
BRL64_02320	COG3711	transcriptional antiterminator
BRL64_02325	COG2226	methyltransferase
BRL64_02330	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_02335	COG3871	stress protein (general stress protein 26)
BRL64_02360	COG2814	Major facilitator Superfamily
BRL64_02365	COG1802	Transcriptional regulator
BRL64_02370	COG2207	Transcriptional regulator
BRL64_02370	COG1917	Cupin 2, conserved barrel domain protein
BRL64_02375	COG0697	spore germination
BRL64_02380	COG0473	3-isopropylmalate dehydrogenase activity
BRL64_02385	COG0551	DNA topoisomerase type I activity
BRL64_02385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BRL64_02390	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BRL64_02395	COG3706	GGDEF domain
BRL64_02400	COG5298	Protein conserved in bacteria
BRL64_02405	COG1215	transferase activity, transferring glycosyl groups
BRL64_02415	COG0531	amino acid
BRL64_02420	COG0028	Belongs to the TPP enzyme family
BRL64_02425	COG5444	nuclease activity
BRL64_02445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRL64_02450	COG1914	H( )-stimulated, divalent metal cation uptake system
BRL64_02455	COG2261	transglycosylase associated protein
BRL64_02460	COG2217	Heavy metal translocating P-type atpase
BRL64_02465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BRL64_02470	COG3290	protein histidine kinase activity
BRL64_02475	COG4565	transcriptional regulatory protein
BRL64_02480	COG1301	dicarboxylic acid transport
BRL64_02485	COG0628	permease
BRL64_02490	COG1301	dicarboxylic acid transport
BRL64_02495	COG1131	(ABC) transporter
BRL64_02500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BRL64_02515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_02520	COG1181	Belongs to the D-alanine--D-alanine ligase family
BRL64_02525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BRL64_02540	COG0513	Belongs to the DEAD box helicase family
BRL64_02545	COG3402	PFAM membrane-flanked domain
BRL64_02550	COG3428	Bacterial PH domain
BRL64_02555	COG0705	Rhomboid family
BRL64_02560	COG0736	holo-[acyl-carrier-protein] synthase activity
BRL64_02565	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BRL64_02570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BRL64_02575	COG0864	Transcriptional regulator
BRL64_02580	COG2337	Toxic component of a toxin-antitoxin (TA) module
BRL64_02585	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_02590	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_02595	COG2172	sigma factor antagonist activity
BRL64_02600	COG2208	phosphoserine phosphatase activity
BRL64_02605	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_02610	COG2172	sigma factor antagonist activity
BRL64_02615	COG1191	sigma factor activity
BRL64_02620	COG2208	phosphoserine phosphatase activity
BRL64_02625	COG2183	response to ionizing radiation
BRL64_02630	COG3091	SprT-like family
BRL64_02635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRL64_02640	COG0022	dehydrogenase e1 component
BRL64_02645	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRL64_02650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRL64_02655	COG3284	Transcriptional regulator
BRL64_02700	COG1278	Cold shock
BRL64_02705	COG1329	Transcriptional regulator
BRL64_02710	COG1064	alcohol dehydrogenase
BRL64_02715	COG0789	Transcriptional regulator
BRL64_02730	COG0477	Major facilitator Superfamily
BRL64_02745	COG4221	oxidoreductase activity
BRL64_02760	COG1404	Belongs to the peptidase S8 family
BRL64_02765	COG0252	asparaginase activity
BRL64_02785	COG2814	Major facilitator Superfamily
BRL64_02790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRL64_02820	COG1309	transcriptional regulator
BRL64_02825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BRL64_02830	COG1846	Transcriptional regulator
BRL64_02835	COG0778	Nitroreductase
BRL64_02850	COG1396	sequence-specific DNA binding
BRL64_02880	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BRL64_02885	COG0697	spore germination
BRL64_02895	COG1301	dicarboxylic acid transport
BRL64_02945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BRL64_02950	COG0802	atpase or kinase
BRL64_02955	COG1214	PFAM Peptidase M22, glycoprotease
BRL64_02960	COG0456	acetyltransferase
BRL64_02965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BRL64_02970	COG0488	(ABC) transporter
BRL64_02975	COG0315	cyclic pyranopterin monophosphate synthase activity
BRL64_02980	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BRL64_02985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BRL64_02990	COG0805	protein transport
BRL64_03005	COG1266	CAAX protease self-immunity
BRL64_03010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BRL64_03015	COG0459	protein refolding
BRL64_03040	COG2808	Putative FMN-binding domain
BRL64_03070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BRL64_03075	COG0823	Involved in the tonB-independent uptake of proteins
BRL64_03085	COG2132	Multicopper oxidase
BRL64_03090	COG1113	amino acid transport
BRL64_03095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BRL64_03100	COG0714	Associated with various cellular activities
BRL64_03105	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BRL64_03110	COG1305	Transglutaminase-like
BRL64_03115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BRL64_03115	COG0519	Catalyzes the synthesis of GMP from XMP
BRL64_03120	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BRL64_03130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BRL64_03135	COG2207	Transcriptional regulator
BRL64_03155	COG1595	DNA-templated transcription, initiation
BRL64_03165	COG2814	Major facilitator Superfamily
BRL64_03170	COG0583	DNA-binding transcription factor activity
BRL64_03175	COG2252	PERMEase
BRL64_03185	COG3064	Membrane
BRL64_03190	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BRL64_03200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BRL64_03205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BRL64_03210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BRL64_03215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BRL64_03220	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BRL64_03225	COG0047	phosphoribosylformylglycinamidine synthase activity
BRL64_03230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BRL64_03235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BRL64_03240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BRL64_03245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BRL64_03250	COG0138	bifunctional purine biosynthesis protein purh
BRL64_03255	COG0151	Belongs to the GarS family
BRL64_03275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BRL64_03280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BRL64_03285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BRL64_03290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRL64_03300	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BRL64_03305	COG4496	protein, YerC YecD
BRL64_03310	COG0069	glutamate synthase activity
BRL64_03325	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BRL64_03330	COG0210	DNA helicase
BRL64_03335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BRL64_03340	COG4851	CamS sex pheromone cAM373 precursor
BRL64_03345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BRL64_03350	COG1285	pathogenesis
BRL64_03355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRL64_03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BRL64_03365	COG0154	amidase activity
BRL64_03370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BRL64_03375	COG1309	transcriptional regulator
BRL64_03380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRL64_03385	COG1957	nucleoside hydrolase
BRL64_03390	COG1597	lipid kinase activity
BRL64_03395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BRL64_03415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BRL64_03425	COG1737	Transcriptional regulator
BRL64_03430	COG1263	PTS System
BRL64_03430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_03435	COG1486	melibiose metabolic process
BRL64_03445	COG1959	2 iron, 2 sulfur cluster binding
BRL64_03450	COG0492	ferredoxin-NADP+ reductase activity
BRL64_03465	COG1486	melibiose metabolic process
BRL64_03475	COG2211	Major facilitator Superfamily
BRL64_03500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BRL64_03505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRL64_03510	COG1442	glycosyl transferase family 8
BRL64_03515	COG1216	Glycosyl transferase, family 2
BRL64_03520	COG1442	glycosyl transferase family 8
BRL64_03525	COG2223	nitrite transmembrane transporter activity
BRL64_03540	COG0693	protein deglycase activity
BRL64_03555	COG0071	Belongs to the small heat shock protein (HSP20) family
BRL64_03570	COG0531	amino acid
BRL64_03575	COG0463	Glycosyl transferase, family 2
BRL64_03575	COG0457	Tetratricopeptide repeat
BRL64_03580	COG0488	(ABC) transporter
BRL64_03585	COG1469	GTP cyclohydrolase I activity
BRL64_03590	COG0789	Transcriptional regulator
BRL64_03595	COG2814	Major facilitator Superfamily
BRL64_03600	COG0488	(ABC) transporter
BRL64_03605	COG0513	Belongs to the DEAD box helicase family
BRL64_03610	COG2130	NADP-dependent
BRL64_03635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BRL64_03635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BRL64_03640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BRL64_03650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRL64_03650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRL64_03660	COG3290	protein histidine kinase activity
BRL64_03665	COG4565	transcriptional regulatory protein
BRL64_03670	COG3181	Tripartite tricarboxylate transporter family receptor
BRL64_03675	COG2851	Citrate transporter
BRL64_03685	COG3479	Phenolic acid decarboxylase
BRL64_03690	COG1695	Transcriptional regulator
BRL64_03695	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BRL64_03700	COG1254	Belongs to the acylphosphatase family
BRL64_03705	COG2258	MOSC domain
BRL64_03720	COG0024	Methionine aminopeptidase
BRL64_03725	COG1263	PTS System
BRL64_03725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_03730	COG3739	integral membrane protein
BRL64_03745	COG1368	sulfuric ester hydrolase activity
BRL64_03755	COG0076	glutamate decarboxylase activity
BRL64_03770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_03770	COG1263	PTS System
BRL64_03775	COG0366	Alpha amylase catalytic
BRL64_03780	COG2188	Transcriptional regulator
BRL64_03790	COG0737	Belongs to the 5'-nucleotidase family
BRL64_03795	COG0693	protein deglycase activity
BRL64_03800	COG4840	Belongs to the UPF0435 family
BRL64_03805	COG1115	amino acid carrier protein
BRL64_03810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BRL64_03815	COG4980	gas vesicle protein
BRL64_03820	COG1295	ribonuclease BN
BRL64_03830	COG0477	Major facilitator Superfamily
BRL64_03840	COG0387	Pfam Sodium calcium exchanger
BRL64_03855	COG0217	transcriptional regulatory protein
BRL64_03860	COG0668	transmembrane transport
BRL64_03865	COG0535	radical SAM domain protein
BRL64_03875	COG0726	polysaccharide deacetylase
BRL64_03880	COG0598	Magnesium transport protein CorA
BRL64_03890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BRL64_03895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BRL64_03910	COG0789	Transcriptional regulator
BRL64_03915	COG2814	Major facilitator Superfamily
BRL64_03965	COG2076	Multidrug Resistance protein
BRL64_03970	COG2076	Multidrug Resistance protein
BRL64_03975	COG1309	transcriptional regulator
BRL64_03985	COG4637	Psort location Cytoplasmic, score
BRL64_03990	COG2755	lipolytic protein G-D-S-L family
BRL64_03995	COG0492	ferredoxin-NADP+ reductase activity
BRL64_04000	COG1742	UPF0060 membrane protein
BRL64_04005	COG1595	DNA-templated transcription, initiation
BRL64_04025	COG2318	DinB family
BRL64_04035	COG1846	Transcriptional regulator
BRL64_04040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BRL64_04040	COG0392	lysyltransferase activity
BRL64_04060	COG0778	Nitroreductase
BRL64_04075	COG1090	epimerase
BRL64_04080	COG2137	regulation of response to DNA damage stimulus
BRL64_04100	COG0463	Glycosyl transferase, family 2
BRL64_04105	COG4485	Bacterial membrane protein, YfhO
BRL64_04115	COG2140	Oxalate decarboxylase
BRL64_04120	COG1191	sigma factor activity
BRL64_04165	COG1988	membrane-bound metal-dependent
BRL64_04170	COG1194	a g-specific adenine glycosylase
BRL64_04180	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_04195	COG3557	Belongs to the UPF0374 family
BRL64_04200	COG1132	(ABC) transporter
BRL64_04205	COG0444	Belongs to the ABC transporter superfamily
BRL64_04210	COG4608	Belongs to the ABC transporter superfamily
BRL64_04215	COG0747	negative chemotaxis
BRL64_04230	COG4129	membrane
BRL64_04235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BRL64_04240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BRL64_04245	COG0735	belongs to the Fur family
BRL64_04395	COG1368	sulfuric ester hydrolase activity
BRL64_04400	COG0681	Belongs to the peptidase S26 family
BRL64_04415	COG1116	anion transmembrane transporter activity
BRL64_04420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BRL64_04425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRL64_04440	COG1131	(ABC) transporter
BRL64_04470	COG3382	B3 4 domain protein
BRL64_04475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BRL64_04485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BRL64_04495	COG2766	serine protein kinase
BRL64_04500	COG2718	Belongs to the UPF0229 family
BRL64_04505	COG1566	PFAM secretion protein HlyD family protein
BRL64_04510	COG2814	Major facilitator Superfamily
BRL64_04515	COG0655	NAD(P)H dehydrogenase (quinone) activity
BRL64_04525	COG1278	Cold shock
BRL64_04530	COG3706	GGDEF domain
BRL64_04555	COG5577	PFAM Coat F domain
BRL64_04560	COG5002	protein histidine kinase activity
BRL64_04565	COG0737	Belongs to the 5'-nucleotidase family
BRL64_04565	COG4085	toxin activity
BRL64_04565	COG1525	nuclease
BRL64_04570	COG3764	Sortase (surface protein transpeptidase)
BRL64_04575	COG0564	pseudouridine synthase activity
BRL64_04585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BRL64_04590	COG3153	acetyltransferase
BRL64_04590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BRL64_04605	COG3835	regulator
BRL64_04610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BRL64_04615	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BRL64_04620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BRL64_04625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BRL64_04630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BRL64_04635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BRL64_04640	COG4585	Histidine kinase
BRL64_04640	COG2203	Gaf domain
BRL64_04645	COG2197	response regulator
BRL64_04660	COG0753	catalase activity
BRL64_04665	COG1959	2 iron, 2 sulfur cluster binding
BRL64_04670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BRL64_04670	COG1017	nitric oxide dioxygenase activity
BRL64_04675	COG2719	SpoVR family
BRL64_04680	COG2721	sulfolactate sulfo-lyase activity
BRL64_04685	COG2186	Transcriptional regulator
BRL64_04690	COG4948	Mandelate Racemase Muconate Lactonizing
BRL64_04695	COG2271	Major facilitator Superfamily
BRL64_04700	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_04705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRL64_04710	COG1785	Belongs to the alkaline phosphatase family
BRL64_04715	COG0791	NLP P60 protein
BRL64_04715	COG1388	LysM domain
BRL64_04720	COG0531	amino acid
BRL64_04735	COG1595	DNA-templated transcription, initiation
BRL64_04740	COG0204	Acyl-transferase
BRL64_04745	COG1253	flavin adenine dinucleotide binding
BRL64_04750	COG0789	Transcriptional regulator
BRL64_04755	COG1253	flavin adenine dinucleotide binding
BRL64_04765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BRL64_04770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BRL64_04775	COG0584	glycerophosphoryl diester phosphodiesterase
BRL64_04780	COG0668	transmembrane transport
BRL64_04785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BRL64_04790	COG0726	polysaccharide deacetylase
BRL64_04795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BRL64_04800	COG0589	response to stress
BRL64_04805	COG1132	(ABC) transporter
BRL64_04810	COG1132	(ABC) transporter
BRL64_04815	COG0702	epimerase
BRL64_04825	COG3842	ATPase activity
BRL64_04830	COG2508	Transcriptional regulator
BRL64_04840	COG0189	ligase activity
BRL64_04845	COG0189	ligase activity
BRL64_04850	COG4399	Belongs to the UPF0754 family
BRL64_04855	COG3679	Belongs to the UPF0342 family
BRL64_04860	COG0561	phosphatase activity
BRL64_04865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRL64_04875	COG0475	glutathione-regulated potassium exporter activity
BRL64_04880	COG0490	domain, Protein
BRL64_04890	COG1024	Enoyl-CoA hydratase
BRL64_04900	COG0420	3'-5' exonuclease activity
BRL64_04905	COG4717	serine-type aminopeptidase activity
BRL64_04910	COG3481	metal-dependent phosphohydrolase, HD sub domain
BRL64_04920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BRL64_04940	COG1846	Transcriptional regulator
BRL64_04945	COG4980	gas vesicle protein
BRL64_04960	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BRL64_04965	COG0537	adenosine 5'-monophosphoramidase activity
BRL64_04970	COG1131	(ABC) transporter
BRL64_04975	COG4473	ABC transporter
BRL64_04985	COG1473	amidohydrolase
BRL64_04995	COG2329	Antibiotic biosynthesis monooxygenase
BRL64_05000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRL64_05005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BRL64_05020	COG1309	transcriptional regulator
BRL64_05025	COG1511	domain protein
BRL64_05030	COG1363	Peptidase, m42
BRL64_05035	COG1301	dicarboxylic acid transport
BRL64_05045	COG1234	tRNA 3'-trailer cleavage
BRL64_05050	COG0095	Lipoate-protein ligase
BRL64_05055	COG0318	PFAM AMP-dependent synthetase and ligase
BRL64_05065	COG0501	Belongs to the peptidase M48B family
BRL64_05070	COG1404	Belongs to the peptidase S8 family
BRL64_05075	COG0406	alpha-ribazole phosphatase activity
BRL64_05080	COG0840	transmembrane signaling receptor activity
BRL64_05085	COG0723	plastoquinol--plastocyanin reductase activity
BRL64_05085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BRL64_05090	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_05100	COG4903	ComK protein
BRL64_05105	COG4974	Belongs to the 'phage' integrase family
BRL64_05110	COG2856	Zn peptidase
BRL64_05120	COG1396	sequence-specific DNA binding
BRL64_05160	COG5377	YqaJ viral recombinase family
BRL64_05165	COG3723	Recombinational DNA repair protein, rece pathway
BRL64_05175	COG1484	DNA-dependent DNA replication
BRL64_05235	COG3677	Transposase
BRL64_05250	COG5484	DNA packaging
BRL64_05310	COG3103	Sh3 type 3 domain protein
BRL64_05310	COG0366	Alpha amylase catalytic
BRL64_05365	COG0456	acetyltransferase
BRL64_05370	COG4978	Transcriptional regulator
BRL64_05370	COG0789	Transcriptional regulator
BRL64_05395	COG2732	(Barnase) inhibitor
BRL64_05400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_05405	COG4605	iron ion homeostasis
BRL64_05410	COG4604	ABC transporter, ATP-binding protein
BRL64_05415	COG4607	ABC-type enterochelin transport system periplasmic component
BRL64_05420	COG1316	TRANSCRIPTIONal
BRL64_05430	COG0398	Pfam SNARE associated Golgi protein
BRL64_05435	COG0681	Belongs to the peptidase S26 family
BRL64_05440	COG3180	Ammonia monooxygenase
BRL64_05450	COG0501	Belongs to the peptidase M48B family
BRL64_05455	COG2259	Doxx family
BRL64_05460	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BRL64_05465	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BRL64_05470	COG1074	ATP-dependent DNA helicase activity
BRL64_05475	COG0420	3'-5' exonuclease activity
BRL64_05480	COG0419	ATPase involved in DNA repair
BRL64_05485	COG1403	HNH endonuclease
BRL64_05525	COG5337	Spore coat protein CotH
BRL64_05540	COG0179	Fumarylacetoacetate (FAA) hydrolase
BRL64_05555	COG0367	asparagine synthase
BRL64_05570	COG1562	ergosterol biosynthetic process
BRL64_05575	COG0534	Mate efflux family protein
BRL64_05580	COG2207	Transcriptional regulator
BRL64_05580	COG1917	Cupin 2, conserved barrel domain protein
BRL64_05605	COG0076	glutamate decarboxylase activity
BRL64_05635	COG0646	methionine synthase
BRL64_05635	COG1410	methionine synthase
BRL64_05640	COG0646	methionine synthase
BRL64_05640	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BRL64_05645	COG1666	GTP binding
BRL64_05650	COG2996	Protein conserved in bacteria
BRL64_05660	COG0840	transmembrane signaling receptor activity
BRL64_05665	COG1307	EDD domain protein, DegV family
BRL64_05670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BRL64_05690	COG0561	phosphatase activity
BRL64_05695	COG1073	alpha beta
BRL64_05700	COG2151	metal-sulfur cluster biosynthetic enzyme
BRL64_05710	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BRL64_05720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BRL64_05725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BRL64_05730	COG0505	Belongs to the CarA family
BRL64_05735	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BRL64_05740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BRL64_05750	COG2814	Major facilitator Superfamily
BRL64_05760	COG2267	carboxylic ester hydrolase activity
BRL64_05770	COG1744	ABC transporter substrate-binding protein PnrA-like
BRL64_05785	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BRL64_05790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BRL64_05795	COG5504	Zn-dependent protease
BRL64_05800	COG0444	Belongs to the ABC transporter superfamily
BRL64_05805	COG4608	Belongs to the ABC transporter superfamily
BRL64_05815	COG0601	transmembrane transport
BRL64_05820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL64_05830	COG0180	Tryptophanyl-tRNA synthetase
BRL64_05835	COG4166	transmembrane transport
BRL64_05840	COG0601	transmembrane transport
BRL64_05845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL64_05850	COG0444	Belongs to the ABC transporter superfamily
BRL64_05855	COG4608	Belongs to the ABC transporter superfamily
BRL64_05865	COG0456	acetyltransferase
BRL64_05870	COG1393	Belongs to the ArsC family
BRL64_05875	COG0861	Integral membrane protein TerC family
BRL64_05880	COG4862	establishment of competence for transformation
BRL64_05885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRL64_05895	COG1164	Oligoendopeptidase f
BRL64_05905	COG2346	COG2346, Truncated hemoglobins
BRL64_05910	COG0741	lytic transglycosylase activity
BRL64_05915	COG4116	CYTH
BRL64_05925	COG2357	RelA SpoT domain protein
BRL64_05930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BRL64_05935	COG0564	pseudouridine synthase activity
BRL64_05940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BRL64_05945	COG0475	glutathione-regulated potassium exporter activity
BRL64_05945	COG0569	domain protein
BRL64_05950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BRL64_05955	COG0352	thiamine-phosphate diphosphorylase activity
BRL64_05965	COG2104	thiamine diphosphate biosynthetic process
BRL64_05970	COG2022	thiamine diphosphate biosynthetic process
BRL64_05975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BRL64_05980	COG0351	phosphomethylpyrimidine kinase
BRL64_05985	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BRL64_06040	COG0210	DNA helicase
BRL64_06050	COG2153	protein acetylation
BRL64_06055	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BRL64_06060	COG2382	esterase
BRL64_06065	COG0626	cystathionine gamma-synthase activity
BRL64_06070	COG0626	cystathionine gamma-synthase activity
BRL64_06090	COG0457	Tetratricopeptide repeat
BRL64_06095	COG1733	regulation of RNA biosynthetic process
BRL64_06105	COG1280	lysine exporter protein (LysE YggA)
BRL64_06110	COG0825	malonyl-CoA metabolic process
BRL64_06135	COG0457	Tetratricopeptide repeat
BRL64_06150	COG3173	Aminoglycoside phosphotransferase
BRL64_06155	COG0583	DNA-binding transcription factor activity
BRL64_06180	COG2807	transmembrane transport
BRL64_06190	COG0457	Tetratricopeptide repeat
BRL64_06215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BRL64_06225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BRL64_06230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BRL64_06235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BRL64_06255	COG4195	phage-related replication protein
BRL64_06260	COG2856	Zn peptidase
BRL64_06265	COG3409	Peptidoglycan-binding domain 1 protein
BRL64_06265	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRL64_06280	COG0306	phosphate transporter
BRL64_06285	COG1392	Phosphate transport regulator
BRL64_06295	COG0405	Gamma-glutamyltransferase
BRL64_06300	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BRL64_06310	COG4208	sulfate ABC transporter
BRL64_06315	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BRL64_06325	COG3775	system Galactitol-specific IIC component
BRL64_06345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRL64_06350	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRL64_06350	COG0022	dehydrogenase e1 component
BRL64_06355	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRL64_06360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRL64_06365	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_06370	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_06375	COG2390	Transcriptional regulator
BRL64_06385	COG0531	amino acid
BRL64_06390	COG0346	lactoylglutathione lyase activity
BRL64_06395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRL64_06400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BRL64_06405	COG2362	D-Aminopeptidase
BRL64_06410	COG0601	transmembrane transport
BRL64_06415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL64_06420	COG0444	Belongs to the ABC transporter superfamily
BRL64_06425	COG4166	transmembrane transport
BRL64_06430	COG1619	proteins homologs of microcin C7 resistance protein MccF
BRL64_06435	COG4948	Mandelate Racemase Muconate Lactonizing
BRL64_06440	COG0791	NLP P60 protein
BRL64_06445	COG4608	Belongs to the ABC transporter superfamily
BRL64_06450	COG1834	amidinotransferase
BRL64_06455	COG1607	acyl-coa hydrolase
BRL64_06460	COG1695	Transcriptional regulator
BRL64_06475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRL64_06490	COG2076	Multidrug Resistance protein
BRL64_06495	COG2076	Multidrug Resistance protein
BRL64_06505	COG0788	formyltetrahydrofolate deformylase activity
BRL64_06510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BRL64_06515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BRL64_06520	COG0457	Tetratricopeptide repeat
BRL64_06530	COG1764	response to oxidative stress
BRL64_06535	COG1846	Transcriptional regulator
BRL64_06540	COG1764	response to oxidative stress
BRL64_06545	COG0590	tRNA wobble adenosine to inosine editing
BRL64_06550	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BRL64_06555	COG1404	Belongs to the peptidase S8 family
BRL64_06560	COG0745	RESPONSE REGULATOR receiver
BRL64_06565	COG5002	protein histidine kinase activity
BRL64_06565	COG3850	Histidine kinase
BRL64_06570	COG3212	peptidase
BRL64_06575	COG3212	peptidase
BRL64_06580	COG2239	Acts as a magnesium transporter
BRL64_06590	COG0789	Transcriptional regulator
BRL64_06600	COG1846	Transcriptional regulator
BRL64_06605	COG3300	MHYT domain
BRL64_06605	COG5001	Diguanylate cyclase
BRL64_06610	COG0586	Pfam SNARE associated Golgi protein
BRL64_06615	COG0861	Integral membrane protein TerC family
BRL64_06620	COG1191	sigma factor activity
BRL64_06640	COG0501	Belongs to the peptidase M48B family
BRL64_06645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BRL64_06655	COG2323	membrane
BRL64_06660	COG3594	Acyltransferase
BRL64_06665	COG5002	protein histidine kinase activity
BRL64_06670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BRL64_06675	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BRL64_06680	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BRL64_06685	COG0436	Aminotransferase
BRL64_06690	COG1850	ribulose-bisphosphate carboxylase activity
BRL64_06695	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BRL64_06700	COG0235	Class ii aldolase
BRL64_06705	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BRL64_06715	COG3852	Histidine kinase
BRL64_06720	COG1846	Transcriptional regulator
BRL64_06725	COG1360	Flagellar Motor Protein
BRL64_06730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BRL64_06735	COG0542	response to heat
BRL64_06740	COG3949	Membrane
BRL64_06745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BRL64_06750	COG0720	synthase
BRL64_06755	COG0602	queuosine metabolic process
BRL64_06760	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BRL64_06770	COG1733	regulation of RNA biosynthetic process
BRL64_06775	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_06790	COG4873	Protein conserved in bacteria
BRL64_06800	COG3773	Cell wall hydrolase
BRL64_06805	COG2244	polysaccharide biosynthetic process
BRL64_06810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_06815	COG2217	Heavy metal translocating P-type atpase
BRL64_06820	COG0006	proline dipeptidase activity
BRL64_06825	COG1609	Transcriptional regulator
BRL64_06830	COG3711	transcriptional antiterminator
BRL64_06835	COG1263	PTS System
BRL64_06835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_06835	COG2190	(PTS) system
BRL64_06840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_06845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BRL64_06855	COG1533	DNA photolyase activity
BRL64_06860	COG0840	transmembrane signaling receptor activity
BRL64_06870	COG2084	Dehydrogenase
BRL64_06875	COG2340	Cysteine-rich secretory protein family
BRL64_06880	COG0768	penicillin binding
BRL64_06885	COG4191	Histidine kinase
BRL64_06890	COG0436	Aminotransferase
BRL64_06895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BRL64_06900	COG1714	RDD family
BRL64_06910	COG0784	Response regulator, receiver
BRL64_06910	COG0835	chemotaxis
BRL64_06920	COG1917	Cupin 2, conserved barrel domain protein
BRL64_06920	COG2207	Transcriptional regulator
BRL64_06925	COG0697	spore germination
BRL64_06935	COG2814	Major facilitator Superfamily
BRL64_06940	COG1376	ErfK ybiS ycfS ynhG family protein
BRL64_06945	COG1408	metallophosphoesterase
BRL64_06950	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_06955	COG2200	EAL domain
BRL64_06960	COG3546	catalase activity
BRL64_06965	COG4703	Protein of unknown function (DUF1797)
BRL64_06970	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BRL64_06980	COG0517	IMP dehydrogenase activity
BRL64_06985	COG0583	DNA-binding transcription factor activity
BRL64_06990	COG0716	FMN binding
BRL64_07000	COG0716	FMN binding
BRL64_07005	COG2171	N-acyltransferase activity
BRL64_07010	COG1473	amidohydrolase
BRL64_07020	COG0668	transmembrane transport
BRL64_07025	COG0450	alkyl hydroperoxide reductase
BRL64_07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_07045	COG0746	molybdenum cofactor guanylyltransferase activity
BRL64_07050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BRL64_07055	COG0303	'Molybdopterin
BRL64_07060	COG1763	Mo-molybdopterin cofactor biosynthetic process
BRL64_07065	COG0314	molybdopterin synthase activity
BRL64_07070	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BRL64_07085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BRL64_07090	COG1136	(ABC) transporter
BRL64_07095	COG0577	efflux transmembrane transporter activity
BRL64_07100	COG1349	DNA-binding transcription factor activity
BRL64_07105	COG1105	Belongs to the carbohydrate kinase PfkB family
BRL64_07110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_07110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_07110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_07115	COG0681	Belongs to the peptidase S26 family
BRL64_07125	COG0488	(ABC) transporter
BRL64_07130	COG2309	aminopeptidase activity
BRL64_07135	COG1077	Cell shape determining protein MreB Mrl
BRL64_07140	COG2002	toxin-antitoxin pair type II binding
BRL64_07145	COG3852	Histidine kinase
BRL64_07150	COG2105	PFAM AIG2 family protein
BRL64_07150	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BRL64_07155	COG0569	domain protein
BRL64_07160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BRL64_07165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BRL64_07175	COG0561	phosphatase activity
BRL64_07180	COG0242	peptide deformylase activity
BRL64_07195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRL64_07200	COG0022	dehydrogenase e1 component
BRL64_07205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRL64_07210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRL64_07215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_07225	COG1982	Orn Lys Arg decarboxylase major
BRL64_07230	COG4476	Belongs to the UPF0223 family
BRL64_07235	COG4493	Belongs to the UPF0637 family
BRL64_07245	COG0483	inositol monophosphate 1-phosphatase activity
BRL64_07270	COG4896	Protein conserved in bacteria
BRL64_07280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BRL64_07285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BRL64_07290	COG2066	Belongs to the glutaminase family
BRL64_07295	COG4838	Belongs to the UPF0358 family
BRL64_07300	COG0772	Belongs to the SEDS family
BRL64_07305	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BRL64_07315	COG1612	heme a metabolic process
BRL64_07320	COG0109	protoheme IX farnesyltransferase activity
BRL64_07325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BRL64_07325	COG2010	Cytochrome c
BRL64_07330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BRL64_07335	COG1845	cytochrome c oxidase, subunit III
BRL64_07340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BRL64_07345	COG3336	cytochrome c oxidase
BRL64_07355	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BRL64_07360	COG2340	Cysteine-rich secretory protein family
BRL64_07380	COG3679	Belongs to the UPF0342 family
BRL64_07385	COG4471	UPF0298 protein
BRL64_07390	COG0742	ribosomal rna small subunit methyltransferase
BRL64_07395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BRL64_07400	COG3314	Sporulation integral membrane protein YlbJ
BRL64_07405	COG1752	Esterase of the alpha-beta hydrolase superfamily
BRL64_07410	COG3480	Lon protease (S16) C-terminal proteolytic domain
BRL64_07420	COG1399	metal-binding, possibly nucleic acid-binding protein
BRL64_07425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BRL64_07435	COG0454	-acetyltransferase
BRL64_07440	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BRL64_07445	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BRL64_07450	COG2001	Belongs to the MraZ family
BRL64_07455	COG0275	rRNA processing
BRL64_07460	COG4839	cell division protein FtsL
BRL64_07470	COG0768	penicillin binding
BRL64_07480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRL64_07485	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BRL64_07490	COG0772	Belongs to the SEDS family
BRL64_07495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BRL64_07500	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BRL64_07505	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BRL64_07510	COG3879	Bacterial protein of unknown function (DUF881)
BRL64_07515	COG3879	Bacterial protein of unknown function (DUF881)
BRL64_07520	COG3856	small basic protein
BRL64_07525	COG0849	cell division
BRL64_07530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BRL64_07535	COG4412	M6 family metalloprotease domain protein
BRL64_07535	COG1404	Belongs to the peptidase S8 family
BRL64_07545	COG1191	sigma factor activity
BRL64_07550	COG1191	sigma factor activity
BRL64_07555	COG2390	Transcriptional regulator
BRL64_07570	COG3730	PTS system glucitol sorbitol-specific
BRL64_07575	COG3732	PTS system glucitol sorbitol-specific
BRL64_07585	COG1119	ATPase activity
BRL64_07590	COG1873	PFAM PRC-barrel domain
BRL64_07600	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BRL64_07605	COG1799	cell septum assembly
BRL64_07610	COG0762	integral membrane protein
BRL64_07615	COG2302	S4 RNA-binding domain
BRL64_07620	COG3599	regulation of cell shape
BRL64_07625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BRL64_07630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BRL64_07635	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BRL64_07640	COG0564	pseudouridine synthase activity
BRL64_07645	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BRL64_07650	COG2233	PERMEase
BRL64_07655	COG0540	Belongs to the ATCase OTCase family
BRL64_07660	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BRL64_07665	COG0505	Belongs to the CarA family
BRL64_07670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BRL64_07675	COG0543	2 iron, 2 sulfur cluster binding
BRL64_07680	COG0167	dihydroorotate dehydrogenase activity
BRL64_07685	COG0284	orotidine-5'-phosphate decarboxylase activity
BRL64_07690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BRL64_07695	COG0175	sulfate reduction
BRL64_07700	COG0306	phosphate transporter
BRL64_07705	COG2046	Belongs to the sulfate adenylyltransferase family
BRL64_07710	COG0529	Catalyzes the synthesis of activated sulfate
BRL64_07715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BRL64_07720	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BRL64_07725	COG1648	precorrin-2 dehydrogenase activity
BRL64_07735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BRL64_07740	COG1561	YicC-like family, N-terminal region
BRL64_07745	COG2052	Domain of unknown function (DUF370)
BRL64_07750	COG0194	GDP metabolic process
BRL64_07755	COG1758	RNA polymerase activity
BRL64_07760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BRL64_07765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BRL64_07770	COG0242	peptide deformylase activity
BRL64_07775	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BRL64_07780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BRL64_07780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRL64_07785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BRL64_07790	COG0631	protein serine/threonine phosphatase activity
BRL64_07795	COG0515	serine threonine protein kinase
BRL64_07795	COG2815	serine threonine protein kinase
BRL64_07800	COG1162	GTPase activity
BRL64_07805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BRL64_07810	COG1564	THIamine pyrophosphokinase
BRL64_07820	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BRL64_07825	COG1302	Protein conserved in bacteria
BRL64_07830	COG1461	Dihydroxyacetone kinase
BRL64_07835	COG1760	l-serine dehydratase
BRL64_07840	COG1760	l-serine dehydratase
BRL64_07845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BRL64_07850	COG1349	DNA-binding transcription factor activity
BRL64_07855	COG0416	fatty acid biosynthetic process
BRL64_07860	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BRL64_07865	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_07870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRL64_07880	COG1196	nuclear chromosome segregation
BRL64_07885	COG0552	protein localization to endoplasmic reticulum
BRL64_07890	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BRL64_07895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BRL64_07900	COG0228	four-way junction DNA binding
BRL64_07905	COG1837	Belongs to the UPF0109 family
BRL64_07915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BRL64_07920	COG0336	Belongs to the RNA methyltransferase TrmD family
BRL64_07925	COG0335	large ribosomal subunit rRNA binding
BRL64_07930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BRL64_07935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BRL64_07945	COG2257	FlhB HrpN YscU SpaS Family
BRL64_07950	COG0045	succinate-CoA ligase (ADP-forming) activity
BRL64_07955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BRL64_07960	COG0758	DNA mediated transformation
BRL64_07965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BRL64_07970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BRL64_07975	COG4974	Belongs to the 'phage' integrase family
BRL64_07980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BRL64_07985	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BRL64_07990	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BRL64_07995	COG1815	bacterial-type flagellum-dependent cell motility
BRL64_08000	COG1558	bacterial-type flagellum-dependent cell motility
BRL64_08005	COG1677	Flagellar hook-basal body complex protein FliE
BRL64_08010	COG1766	The M ring may be actively involved in energy transduction
BRL64_08015	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BRL64_08020	COG1317	bacterial-type flagellum organization
BRL64_08025	COG1157	protein secretion by the type III secretion system
BRL64_08030	COG2882	bacterial-type flagellum organization
BRL64_08035	COG3334	PFAM MgtE intracellular
BRL64_08040	COG3144	bacterial-type flagellum assembly
BRL64_08045	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BRL64_08050	COG4786	Flagellar basal body rod
BRL64_08055	COG1582	Flagellar protein (FlbD)
BRL64_08060	COG1580	Controls the rotational direction of flagella during chemotaxis
BRL64_08065	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BRL64_08070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BRL64_08070	COG1776	CheC inhibitor of MCP methylation
BRL64_08075	COG2201	protein-glutamate methylesterase activity
BRL64_08080	COG3190	flagellar
BRL64_08085	COG1338	Plays a role in the flagellum-specific transport system
BRL64_08090	COG1987	bacterial-type flagellum assembly
BRL64_08095	COG1684	flagellar biosynthetic protein fliR
BRL64_08100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BRL64_08105	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BRL64_08110	COG1419	protein localization to endoplasmic reticulum
BRL64_08115	COG0455	bacterial-type flagellum organization
BRL64_08120	COG2201	protein-glutamate methylesterase activity
BRL64_08125	COG2198	Histidine kinase
BRL64_08125	COG0643	Histidine kinase
BRL64_08130	COG0835	chemotaxis
BRL64_08135	COG1776	CheC inhibitor of MCP methylation
BRL64_08145	COG1191	sigma factor activity
BRL64_08160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BRL64_08165	COG0528	UMP kinase activity
BRL64_08170	COG0233	cytoplasmic translational termination
BRL64_08175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BRL64_08180	COG4589	Belongs to the CDS family
BRL64_08185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BRL64_08190	COG0750	zinc metalloprotease
BRL64_08195	COG0442	prolyl-tRNA aminoacylation
BRL64_08200	COG2176	DNA-directed DNA polymerase activity
BRL64_08235	COG1131	(ABC) transporter
BRL64_08280	COG0779	Required for maturation of 30S ribosomal subunits
BRL64_08285	COG0195	Participates in both transcription termination and antitermination
BRL64_08290	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BRL64_08295	COG1358	cellular component organization or biogenesis
BRL64_08300	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BRL64_08305	COG1550	Protein conserved in bacteria
BRL64_08310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BRL64_08315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BRL64_08320	COG0196	riboflavin kinase activity
BRL64_08325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BRL64_08330	COG1185	polyribonucleotide nucleotidyltransferase activity
BRL64_08335	COG0726	polysaccharide deacetylase
BRL64_08340	COG0612	Peptidase, M16
BRL64_08345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRL64_08355	COG1132	(ABC) transporter
BRL64_08360	COG1132	(ABC) transporter
BRL64_08395	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
BRL64_08405	COG2255	four-way junction helicase activity
BRL64_08415	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_08420	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_08425	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BRL64_08430	COG1260	myo-inositol-1-phosphate synthase
BRL64_08475	COG0367	asparagine synthase
BRL64_08480	COG1873	PFAM PRC-barrel domain
BRL64_08485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRL64_08490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BRL64_08495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BRL64_08500	COG0527	aspartate kinase activity
BRL64_08510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BRL64_08515	COG0740	serine-type endopeptidase activity
BRL64_08525	COG1674	ftsk spoiiie
BRL64_08525	COG4980	gas vesicle protein
BRL64_08530	COG2188	Transcriptional regulator
BRL64_08535	COG2814	Major facilitator Superfamily
BRL64_08540	COG2409	Drug exporters of the RND superfamily
BRL64_08540	COG1033	growth of symbiont in host cell
BRL64_08545	COG0612	Peptidase, M16
BRL64_08550	COG0612	Peptidase, M16
BRL64_08560	COG2409	Drug exporters of the RND superfamily
BRL64_08560	COG1033	growth of symbiont in host cell
BRL64_08565	COG0300	oxidoreductase activity
BRL64_08580	COG1426	Protein conserved in bacteria
BRL64_08585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BRL64_08590	COG1546	Belongs to the CinA family
BRL64_08590	COG1058	Belongs to the CinA family
BRL64_08595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BRL64_08600	COG1418	mRNA catabolic process
BRL64_08605	COG1692	metallophosphoesterase
BRL64_08610	COG2359	stage V sporulation protein S
BRL64_08615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BRL64_08620	COG1063	alcohol dehydrogenase
BRL64_08625	COG0156	8-amino-7-oxononanoate synthase activity
BRL64_08630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BRL64_08635	COG4550	Control of competence regulator ComK, YlbF/YmcA
BRL64_08645	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BRL64_08650	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BRL64_08670	COG1329	Transcriptional regulator
BRL64_08675	COG4195	phage-related replication protein
BRL64_08680	COG0457	Tetratricopeptide repeat
BRL64_08685	COG1404	Belongs to the peptidase S8 family
BRL64_08690	COG4195	phage-related replication protein
BRL64_08695	COG1764	response to oxidative stress
BRL64_08700	COG2076	Multidrug Resistance protein
BRL64_08725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BRL64_08730	COG1923	regulation of RNA biosynthetic process
BRL64_08745	COG1780	Probably involved in ribonucleotide reductase function
BRL64_08750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRL64_08755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BRL64_08760	COG4112	unkown
BRL64_08770	COG0464	growth
BRL64_08775	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BRL64_08780	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BRL64_08785	COG0789	Transcriptional regulator
BRL64_08790	COG0174	glutamine synthetase
BRL64_08805	COG1752	Esterase of the alpha-beta hydrolase superfamily
BRL64_08855	COG0457	Tetratricopeptide repeat
BRL64_08860	COG5444	nuclease activity
BRL64_08885	COG5646	InterPro IPR014922
BRL64_08890	COG0457	Tetratricopeptide repeat
BRL64_08895	COG3619	membrane
BRL64_08900	COG1793	dna ligase
BRL64_08900	COG3285	dna ligase
BRL64_08905	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BRL64_08910	COG4876	unkown
BRL64_08920	COG1959	2 iron, 2 sulfur cluster binding
BRL64_08925	COG0702	epimerase
BRL64_08930	COG0247	lactate metabolic process
BRL64_08935	COG1139	Iron-sulfur cluster binding protein
BRL64_08940	COG1556	Lactate utilization protein
BRL64_08960	COG2323	membrane
BRL64_08965	COG1309	transcriptional regulator
BRL64_08970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BRL64_08970	COG2124	cytochrome p450
BRL64_08975	COG3591	Belongs to the peptidase S1B family
BRL64_08980	COG3209	COG3209 Rhs family protein
BRL64_08985	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_09000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BRL64_09005	COG1388	LysM domain
BRL64_09010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BRL64_09015	COG4224	UPF0291 protein
BRL64_09020	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BRL64_09030	COG3763	UPF0154 protein
BRL64_09040	COG0785	Cytochrome C biogenesis protein
BRL64_09045	COG4846	Membrane protein involved in cytochrome C biogenesis
BRL64_09055	COG0071	Belongs to the small heat shock protein (HSP20) family
BRL64_09070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BRL64_09075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_09095	COG0824	Thioesterase
BRL64_09105	COG4841	protein insertion into membrane
BRL64_09110	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BRL64_09115	COG1832	CoA-binding protein
BRL64_09120	COG0187	DNA topoisomerase II activity
BRL64_09125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BRL64_09135	COG0738	Major facilitator superfamily
BRL64_09140	COG0110	maltose O-acetyltransferase activity
BRL64_09150	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BRL64_09155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BRL64_09170	COG2249	NAD(P)H dehydrogenase (quinone) activity
BRL64_09175	COG1733	regulation of RNA biosynthetic process
BRL64_09185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BRL64_09190	COG0251	oxidation-reduction process
BRL64_09200	COG1082	Xylose isomerase domain protein TIM barrel
BRL64_09205	COG0673	inositol 2-dehydrogenase activity
BRL64_09210	COG2814	Major facilitator Superfamily
BRL64_09215	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_09225	COG3718	enzyme involved in inositol metabolism
BRL64_09230	COG3962	Belongs to the TPP enzyme family
BRL64_09235	COG1349	DNA-binding transcription factor activity
BRL64_09240	COG0191	fructose-bisphosphate aldolase activity
BRL64_09245	COG1082	Xylose isomerase domain protein TIM barrel
BRL64_09250	COG2814	Major facilitator Superfamily
BRL64_09265	COG0789	Transcriptional regulator
BRL64_09275	COG2205	protein histidine kinase activity
BRL64_09280	COG0745	RESPONSE REGULATOR receiver
BRL64_09290	COG3507	Belongs to the glycosyl hydrolase 43 family
BRL64_09295	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_09300	COG1486	melibiose metabolic process
BRL64_09325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BRL64_09340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_09370	COG5444	nuclease activity
BRL64_09375	COG1846	Transcriptional regulator
BRL64_09390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_09390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_09390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_09395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_09395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_09395	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BRL64_09400	COG1105	Belongs to the carbohydrate kinase PfkB family
BRL64_09410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRL64_09440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BRL64_09445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRL64_09450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRL64_09455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BRL64_09460	COG1024	Enoyl-CoA hydratase
BRL64_09465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BRL64_09470	COG0511	ligase activity, forming carbon-carbon bonds
BRL64_09475	COG0439	Biotin carboxylase
BRL64_09480	COG0318	PFAM AMP-dependent synthetase and ligase
BRL64_09485	COG1960	acyl-CoA dehydrogenase activity
BRL64_09490	COG1649	PFAM Uncharacterised BCR, COG1649
BRL64_09500	COG1349	DNA-binding transcription factor activity
BRL64_09510	COG3835	regulator
BRL64_09515	COG0277	FAD linked oxidase domain protein
BRL64_09520	COG0247	lactate metabolic process
BRL64_09545	COG0166	Belongs to the GPI family
BRL64_09550	COG0586	Pfam SNARE associated Golgi protein
BRL64_09555	COG1587	Uroporphyrinogen-III synthase
BRL64_09565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRL64_09580	COG0534	Mate efflux family protein
BRL64_09585	COG2027	D-alanyl-D-alanine carboxypeptidase
BRL64_09590	COG4677	pectinesterase activity
BRL64_09595	COG2323	membrane
BRL64_09600	COG2146	nitrite reductase [NAD(P)H] activity
BRL64_09605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRL64_09610	COG0243	molybdopterin cofactor binding
BRL64_09615	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BRL64_09620	COG2223	nitrite transmembrane transporter activity
BRL64_09625	COG0493	'glutamate synthase
BRL64_09630	COG0070	glutamate synthase
BRL64_09630	COG0069	glutamate synthase activity
BRL64_09630	COG0067	glutamate synthase
BRL64_09635	COG0583	DNA-binding transcription factor activity
BRL64_09650	COG4978	Transcriptional regulator
BRL64_09650	COG0789	Transcriptional regulator
BRL64_09655	COG0454	-acetyltransferase
BRL64_09660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BRL64_09665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BRL64_09680	COG0243	molybdopterin cofactor binding
BRL64_09690	COG1070	Carbohydrate kinase
BRL64_09695	COG2115	Belongs to the xylose isomerase family
BRL64_09710	COG2211	Major facilitator Superfamily
BRL64_09715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRL64_09720	COG1994	Peptidase M50
BRL64_09740	COG1309	transcriptional regulator
BRL64_09745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRL64_09750	COG3708	Transcriptional regulator
BRL64_09755	COG2378	regulation of single-species biofilm formation
BRL64_09765	COG0640	Transcriptional regulator
BRL64_09770	COG0531	amino acid
BRL64_09775	COG0741	lytic transglycosylase activity
BRL64_09780	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BRL64_09785	COG2079	MmgE PrpD family protein
BRL64_09790	COG0372	Belongs to the citrate synthase family
BRL64_09795	COG2322	membrane
BRL64_09805	COG1388	LysM domain
BRL64_09805	COG3584	3D domain protein
BRL64_09810	COG0514	ATP-dependent DNA helicase (RecQ)
BRL64_09820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BRL64_09840	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_09845	COG1657	PFAM Prenyltransferase squalene oxidase
BRL64_09850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BRL64_09855	COG0385	Bile acid
BRL64_09860	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRL64_09865	COG0567	Dehydrogenase, E1 component
BRL64_09870	COG4548	von Willebrand factor, type A
BRL64_09875	COG0714	Associated with various cellular activities
BRL64_09880	COG2032	superoxide dismutase activity
BRL64_09885	COG0791	NLP P60 protein
BRL64_09885	COG1388	LysM domain
BRL64_09890	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BRL64_09895	COG0534	Mate efflux family protein
BRL64_09900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BRL64_09905	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BRL64_09915	COG2962	Rard protein
BRL64_09930	COG1733	regulation of RNA biosynthetic process
BRL64_09935	COG0778	Nitroreductase
BRL64_09945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRL64_09950	COG3409	Peptidoglycan-binding domain 1 protein
BRL64_09950	COG0793	Belongs to the peptidase S41A family
BRL64_09955	COG2226	methyltransferase
BRL64_09965	COG1876	peptidase activity
BRL64_09970	COG0813	purine-nucleoside phosphorylase activity
BRL64_09980	COG0671	phosphoesterase, PA-phosphatase related
BRL64_09995	COG4479	Belongs to the UPF0346 family
BRL64_10005	COG1509	lysine 2,3-aminomutase activity
BRL64_10010	COG3829	transcription factor binding
BRL64_10015	COG0463	Glycosyl transferase, family 2
BRL64_10030	COG4641	Protein conserved in bacteria
BRL64_10040	COG1086	Polysaccharide biosynthesis protein
BRL64_10045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BRL64_10050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BRL64_10055	COG1846	Transcriptional regulator
BRL64_10075	COG4698	Protein conserved in bacteria
BRL64_10080	COG2755	lipolytic protein G-D-S-L family
BRL64_10085	COG1999	signal sequence binding
BRL64_10100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BRL64_10105	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BRL64_10110	COG1272	protein, Hemolysin III
BRL64_10115	COG0204	Acyl-transferase
BRL64_10120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BRL64_10125	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BRL64_10130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BRL64_10140	COG2136	Putative SAM-dependent methyltransferase
BRL64_10140	COG2521	methyltransferase
BRL64_10150	COG0129	dihydroxy-acid dehydratase activity
BRL64_10155	COG1413	lyase activity
BRL64_10160	COG1418	mRNA catabolic process
BRL64_10165	COG0386	Belongs to the glutathione peroxidase family
BRL64_10170	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BRL64_10175	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BRL64_10180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BRL64_10190	COG1278	Cold shock
BRL64_10205	COG0328	RNA-DNA hybrid ribonuclease activity
BRL64_10210	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BRL64_10215	COG0328	RNA-DNA hybrid ribonuclease activity
BRL64_10225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRL64_10235	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BRL64_10240	COG1755	Isoprenylcysteine carboxyl methyltransferase
BRL64_10245	COG3424	synthase
BRL64_10250	COG0726	polysaccharide deacetylase
BRL64_10255	COG2233	PERMEase
BRL64_10260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BRL64_10265	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BRL64_10270	COG1199	ATP-dependent helicase activity
BRL64_10280	COG0116	Belongs to the methyltransferase superfamily
BRL64_10290	COG3599	regulation of cell shape
BRL64_10295	COG4474	Belongs to the UPF0398 family
BRL64_10300	COG3359	exonuclease
BRL64_10305	COG1205	dead DEAH box helicase
BRL64_10305	COG1111	helicase
BRL64_10310	COG1902	pentaerythritol trinitrate reductase activity
BRL64_10315	COG2190	(PTS) system
BRL64_10320	COG0071	Belongs to the small heat shock protein (HSP20) family
BRL64_10350	COG3331	DNA recombination
BRL64_10355	COG4499	WXG100 protein secretion system (Wss), protein YukC
BRL64_10355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRL64_10365	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BRL64_10370	COG3935	DnaD domain protein
BRL64_10375	COG0017	Asparaginyl-tRNA synthetase
BRL64_10380	COG5353	protein conserved in bacteria
BRL64_10390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BRL64_10390	COG1199	ATP-dependent helicase activity
BRL64_10395	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BRL64_10400	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BRL64_10405	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BRL64_10415	COG0617	tRNA 3'-terminal CCA addition
BRL64_10420	COG0438	transferase activity, transferring glycosyl groups
BRL64_10425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BRL64_10430	COG1803	Methylglyoxal synthase
BRL64_10435	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BRL64_10440	COG1694	Mazg nucleotide pyrophosphohydrolase
BRL64_10445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BRL64_10455	COG4347	Protein of unknown function (DUF1405)
BRL64_10460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BRL64_10460	COG2010	Cytochrome c
BRL64_10465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BRL64_10470	COG0723	plastoquinol--plastocyanin reductase activity
BRL64_10480	COG5582	Belongs to the UPF0302 family
BRL64_10485	COG0457	Tetratricopeptide repeat
BRL64_10490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BRL64_10495	COG0287	Prephenate dehydrogenase
BRL64_10500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BRL64_10505	COG0159	tryptophan synthase activity
BRL64_10510	COG0133	tryptophan synthase activity
BRL64_10515	COG0135	phosphoribosylanthranilate isomerase activity
BRL64_10520	COG0134	indole-3-glycerol-phosphate synthase activity
BRL64_10535	COG4401	Chorismate mutase type I
BRL64_10540	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BRL64_10545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BRL64_10550	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BRL64_10555	COG0105	UTP biosynthetic process
BRL64_10560	COG0142	geranyltranstransferase activity
BRL64_10565	COG2226	methyltransferase
BRL64_10570	COG0142	geranyltranstransferase activity
BRL64_10580	COG0302	gtp cyclohydrolase
BRL64_10585	COG0776	regulation of translation
BRL64_10590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BRL64_10605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BRL64_10610	COG1160	GTP binding
BRL64_10635	COG1304	FMN binding
BRL64_10640	COG0539	negative regulation of cytoplasmic translation
BRL64_10645	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BRL64_10655	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BRL64_10660	COG2959	enzyme of heme biosynthesis
BRL64_10665	COG3409	Peptidoglycan-binding domain 1 protein
BRL64_10665	COG3773	Cell wall hydrolase
BRL64_10670	COG2339	peptidase activity
BRL64_10675	COG0492	ferredoxin-NADP+ reductase activity
BRL64_10680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BRL64_10685	COG4862	establishment of competence for transformation
BRL64_10690	COG1408	metallophosphoesterase
BRL64_10700	COG1388	LysM domain
BRL64_10705	COG1266	CAAX protease self-immunity
BRL64_10710	COG0514	ATP-dependent DNA helicase (RecQ)
BRL64_10715	COG4955	Helix-turn-helix domain
BRL64_10720	COG1141	Ferredoxin
BRL64_10725	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BRL64_10730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BRL64_10735	COG3409	Peptidoglycan-binding domain 1 protein
BRL64_10735	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRL64_10745	COG1595	DNA-templated transcription, initiation
BRL64_10750	COG5002	protein histidine kinase activity
BRL64_10755	COG0745	RESPONSE REGULATOR receiver
BRL64_10760	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRL64_10765	COG1333	cytochrome c biogenesis protein
BRL64_10770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_10775	COG1187	pseudouridine synthase activity
BRL64_10780	COG0700	Nucleoside recognition
BRL64_10785	COG2715	membrane protein required for spore maturation
BRL64_10790	COG1686	Belongs to the peptidase S11 family
BRL64_10800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BRL64_10805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BRL64_10810	COG1547	Domain of unknown function (DUF309)
BRL64_10815	COG0456	acetyltransferase
BRL64_10820	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BRL64_10830	COG0307	riboflavin synthase, alpha
BRL64_10850	COG2814	Major facilitator Superfamily
BRL64_10855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BRL64_10860	COG4086	secreted protein
BRL64_10865	COG0019	diaminopimelate decarboxylase activity
BRL64_10870	COG0697	spore germination
BRL64_10885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BRL64_10905	COG1191	sigma factor activity
BRL64_10910	COG2172	sigma factor antagonist activity
BRL64_10920	COG1686	Belongs to the peptidase S11 family
BRL64_10925	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BRL64_10930	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BRL64_10935	COG4974	Belongs to the 'phage' integrase family
BRL64_10945	COG0735	belongs to the Fur family
BRL64_10950	COG1300	Membrane
BRL64_10955	COG1404	Belongs to the peptidase S8 family
BRL64_10965	COG2153	protein acetylation
BRL64_10970	COG1379	DNA repair
BRL64_10975	COG0494	nUDIX hydrolase
BRL64_10980	COG0667	Aldo Keto reductase
BRL64_10995	COG1073	alpha beta
BRL64_11000	COG0457	Tetratricopeptide repeat
BRL64_11010	COG4918	Iron-sulphur cluster biosynthesis
BRL64_11015	COG0456	acetyltransferase
BRL64_11015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BRL64_11020	COG0456	acetyltransferase
BRL64_11030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BRL64_11040	COG2211	Major facilitator Superfamily
BRL64_11045	COG1072	(Pantothenic acid kinase))
BRL64_11055	COG0300	oxidoreductase activity
BRL64_11060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRL64_11065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BRL64_11080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRL64_11085	COG4187	Peptidase family M20/M25/M40
BRL64_11090	COG1902	pentaerythritol trinitrate reductase activity
BRL64_11095	COG0596	Alpha beta hydrolase
BRL64_11100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BRL64_11110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BRL64_11115	COG2188	Transcriptional regulator
BRL64_11120	COG2723	6-phospho-beta-galactosidase activity
BRL64_11125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BRL64_11130	COG1447	Phosphotransferase system cellobiose-specific component IIA
BRL64_11135	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BRL64_11140	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_11150	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BRL64_11155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BRL64_11170	COG0706	membrane insertase activity
BRL64_11180	COG2195	Cleaves the N-terminal amino acid of tripeptides
BRL64_11185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BRL64_11190	COG0346	lactoylglutathione lyase activity
BRL64_11195	COG1376	ErfK ybiS ycfS ynhG family protein
BRL64_11200	COG4129	membrane
BRL64_11205	COG1126	abc transporter atp-binding protein
BRL64_11210	COG0765	amino acid transport
BRL64_11215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL64_11225	COG1597	lipid kinase activity
BRL64_11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
BRL64_11240	COG0022	dehydrogenase e1 component
BRL64_11245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BRL64_11250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BRL64_11255	COG3426	butyrate kinase activity
BRL64_11260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BRL64_11265	COG0280	phosphate acetyltransferase
BRL64_11270	COG3290	protein histidine kinase activity
BRL64_11270	COG3829	transcription factor binding
BRL64_11280	COG0584	glycerophosphoryl diester phosphodiesterase
BRL64_11285	COG0457	Tetratricopeptide repeat
BRL64_11295	COG0745	RESPONSE REGULATOR receiver
BRL64_11300	COG0750	zinc metalloprotease
BRL64_11305	COG0497	DNA recombination
BRL64_11310	COG1438	arginine binding
BRL64_11315	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BRL64_11320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BRL64_11325	COG0142	geranyltranstransferase activity
BRL64_11330	COG1722	exodeoxyribonuclease VII activity
BRL64_11335	COG1570	exodeoxyribonuclease VII activity
BRL64_11340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BRL64_11345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BRL64_11350	COG1302	Protein conserved in bacteria
BRL64_11355	COG0439	Biotin carboxylase
BRL64_11360	COG0511	ligase activity, forming carbon-carbon bonds
BRL64_11400	COG3854	ATPases associated with a variety of cellular activities
BRL64_11410	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BRL64_11415	COG0006	proline dipeptidase activity
BRL64_11420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BRL64_11430	COG3872	metal-dependent enzyme
BRL64_11440	COG1752	Esterase of the alpha-beta hydrolase superfamily
BRL64_11445	COG1321	iron dependent repressor
BRL64_11450	COG0095	Lipoate-protein ligase
BRL64_11455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRL64_11460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BRL64_11465	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BRL64_11470	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BRL64_11475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BRL64_11495	COG0681	Belongs to the peptidase S26 family
BRL64_11530	COG4970	Tfp pilus assembly protein FimT
BRL64_11535	COG4537	Required for transformation and DNA binding
BRL64_11540	COG1459	type II secretion system
BRL64_11545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BRL64_11550	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_11560	COG1393	Belongs to the ArsC family
BRL64_11570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRL64_11580	COG0011	TIGRFAM Protein of
BRL64_11585	COG2814	Major facilitator Superfamily
BRL64_11590	COG2866	Carboxypeptidase
BRL64_11595	COG1368	sulfuric ester hydrolase activity
BRL64_11600	COG1940	carbohydrate kinase activity
BRL64_11605	COG4483	Protein conserved in bacteria
BRL64_11610	COG0457	Tetratricopeptide repeat
BRL64_11610	COG0705	Rhomboid family
BRL64_11620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BRL64_11625	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BRL64_11635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BRL64_11640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BRL64_11645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BRL64_11650	COG0581	inorganic phosphate transmembrane transporter activity
BRL64_11655	COG0573	inorganic phosphate transmembrane transporter activity
BRL64_11660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BRL64_11670	COG0477	Major facilitator Superfamily
BRL64_11675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BRL64_11680	COG2839	Protein conserved in bacteria
BRL64_11685	COG5521	maltodextrose utilization protein MalA
BRL64_11690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BRL64_11695	COG1388	LysM domain
BRL64_11700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BRL64_11705	COG4709	membrane
BRL64_11710	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BRL64_11715	COG1940	carbohydrate kinase activity
BRL64_11720	COG0735	belongs to the Fur family
BRL64_11725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BRL64_11730	COG1121	(ABC) transporter
BRL64_11735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BRL64_11750	COG0513	Belongs to the DEAD box helicase family
BRL64_11760	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BRL64_11765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BRL64_11770	COG2384	SAM-dependent methyltransferase
BRL64_11775	COG2010	Cytochrome c
BRL64_11780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BRL64_11785	COG0358	DNA primase activity
BRL64_11790	COG1671	Belongs to the UPF0178 family
BRL64_11795	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BRL64_11800	COG0517	IMP dehydrogenase activity
BRL64_11805	COG0751	glycine-tRNA ligase activity
BRL64_11810	COG0752	glycyl-tRNA synthetase alpha subunit
BRL64_11815	COG1381	Involved in DNA repair and RecF pathway recombination
BRL64_11825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BRL64_11830	COG0295	cytidine deaminase activity
BRL64_11835	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BRL64_11840	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BRL64_11845	COG1480	7TM receptor with intracellular HD hydrolase
BRL64_11850	COG1702	phosphate starvation-inducible protein PhoH
BRL64_11855	COG0561	phosphatase activity
BRL64_11870	COG4864	UPF0365 protein
BRL64_11875	COG1030	water channel activity
BRL64_11880	COG1610	YqeY-like protein
BRL64_11885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BRL64_11890	COG1283	sodium-dependent phosphate transmembrane transporter activity
BRL64_11895	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BRL64_11900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BRL64_11905	COG2264	protein methyltransferase activity
BRL64_11910	COG0484	heat shock protein binding
BRL64_11915	COG0443	Heat shock 70 kDa protein
BRL64_11920	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BRL64_11925	COG1420	regulation of RNA biosynthetic process
BRL64_11930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BRL64_11935	COG0481	GTPase activity
BRL64_11945	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRL64_11950	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BRL64_11955	COG0268	Binds directly to 16S ribosomal RNA
BRL64_11960	COG1466	dna polymerase III delta subunit
BRL64_11970	COG0658	competence protein
BRL64_11970	COG2333	competence protein COMEC
BRL64_11975	COG2131	deaminase
BRL64_11980	COG1555	photosystem II stabilization
BRL64_11985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BRL64_11990	COG2226	methyltransferase
BRL64_11995	COG0799	negative regulation of ribosome biogenesis
BRL64_12000	COG1713	HD superfamily hydrolase involved in NAD metabolism
BRL64_12005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BRL64_12010	COG1534	Rna-binding protein
BRL64_12015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRL64_12020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BRL64_12025	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BRL64_12035	COG2755	lipolytic protein G-D-S-L family
BRL64_12045	COG0457	Tetratricopeptide repeat
BRL64_12055	COG2318	DinB family
BRL64_12080	COG0726	polysaccharide deacetylase
BRL64_12110	COG2160	L-arabinose isomerase activity
BRL64_12125	COG1609	Transcriptional regulator
BRL64_12135	COG1846	Transcriptional regulator
BRL64_12145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BRL64_12150	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BRL64_12155	COG1733	regulation of RNA biosynthetic process
BRL64_12185	COG2602	Beta-lactamase
BRL64_12190	COG1960	acyl-CoA dehydrogenase activity
BRL64_12195	COG1126	abc transporter atp-binding protein
BRL64_12205	COG0765	amino acid transport
BRL64_12215	COG3546	catalase activity
BRL64_12220	COG1063	alcohol dehydrogenase
BRL64_12230	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_12235	COG1132	(ABC) transporter
BRL64_12240	COG0454	-acetyltransferase
BRL64_12245	COG2226	methyltransferase
BRL64_12250	COG1063	alcohol dehydrogenase
BRL64_12255	COG2226	methyltransferase
BRL64_12270	COG0626	cystathionine gamma-synthase activity
BRL64_12275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BRL64_12280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BRL64_12285	COG2226	methyltransferase
BRL64_12300	COG0768	penicillin binding
BRL64_12305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BRL64_12315	COG0572	uridine kinase
BRL64_12335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BRL64_12340	COG0183	Belongs to the thiolase family
BRL64_12345	COG0318	PFAM AMP-dependent synthetase and ligase
BRL64_12350	COG1268	BioY protein
BRL64_12355	COG3906	Belongs to the UPF0473 family
BRL64_12360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BRL64_12365	COG4472	Bacterial protein of unknown function (DUF965)
BRL64_12370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BRL64_12375	COG0628	permease
BRL64_12380	COG1126	abc transporter atp-binding protein
BRL64_12385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL64_12390	COG0765	amino acid transport
BRL64_12395	COG0765	amino acid transport
BRL64_12410	COG3881	PFAM PRC-barrel domain
BRL64_12415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BRL64_12420	COG0457	Tetratricopeptide repeat
BRL64_12425	COG0482	sulfurtransferase activity
BRL64_12430	COG1104	cysteine desulfurase activity
BRL64_12435	COG1959	2 iron, 2 sulfur cluster binding
BRL64_12440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BRL64_12445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BRL64_12460	COG0124	histidyl-tRNA synthetase
BRL64_12465	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRL64_12465	COG4991	sh3 domain protein
BRL64_12465	COG3103	Sh3 type 3 domain protein
BRL64_12470	COG1490	D-aminoacyl-tRNA deacylase activity
BRL64_12475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BRL64_12480	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BRL64_12485	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BRL64_12485	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BRL64_12490	COG5416	Lipopolysaccharide assembly protein A domain
BRL64_12495	COG0490	domain, Protein
BRL64_12500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRL64_12500	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BRL64_12510	COG2244	polysaccharide biosynthetic process
BRL64_12515	COG2323	membrane
BRL64_12525	COG1862	Preprotein translocase
BRL64_12530	COG0343	queuine tRNA-ribosyltransferase activity
BRL64_12535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BRL64_12545	COG2255	four-way junction helicase activity
BRL64_12550	COG0632	four-way junction helicase activity
BRL64_12560	COG2112	serine threonine protein kinase
BRL64_12570	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BRL64_12585	COG1388	LysM domain
BRL64_12585	COG1388	LysM domain
BRL64_12590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BRL64_12595	COG0157	Belongs to the NadC ModD family
BRL64_12600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BRL64_12605	COG1104	cysteine desulfurase activity
BRL64_12610	COG1827	regulation of RNA biosynthetic process
BRL64_12615	COG0077	Prephenate dehydratase
BRL64_12620	COG4492	Belongs to the UPF0735 family
BRL64_12625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BRL64_12630	COG3290	protein histidine kinase activity
BRL64_12635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BRL64_12640	COG2868	ribosomal protein
BRL64_12645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BRL64_12650	COG1994	Peptidase M50
BRL64_12655	COG0739	heme binding
BRL64_12660	COG2894	cell division
BRL64_12665	COG0850	regulation of cytokinetic process
BRL64_12670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BRL64_12675	COG1792	Involved in formation and maintenance of cell shape
BRL64_12680	COG1077	Cell shape determining protein MreB Mrl
BRL64_12685	COG2003	Belongs to the UPF0758 family
BRL64_12690	COG0424	maF-like protein
BRL64_12705	COG0285	dihydrofolate synthase activity
BRL64_12710	COG0525	valine-tRNA ligase activity
BRL64_12720	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BRL64_12725	COG1388	LysM domain
BRL64_12730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BRL64_12735	COG0113	porphobilinogen synthase activity
BRL64_12740	COG1587	Uroporphyrinogen-III synthase
BRL64_12745	COG0181	hydroxymethylbilane synthase activity
BRL64_12750	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BRL64_12755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BRL64_12765	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BRL64_12770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BRL64_12775	COG1067	ATP-dependent peptidase activity
BRL64_12775	COG0470	DNA polymerase III
BRL64_12780	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BRL64_12785	COG0544	peptidyl-prolyl cis-trans isomerase activity
BRL64_12790	COG0457	Tetratricopeptide repeat
BRL64_12790	COG1477	protein flavinylation
BRL64_12795	COG0066	3-isopropylmalate dehydratase activity
BRL64_12800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BRL64_12805	COG0473	3-isopropylmalate dehydrogenase activity
BRL64_12810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BRL64_12815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BRL64_12820	COG0440	acetolactate synthase activity
BRL64_12825	COG0028	Belongs to the TPP enzyme family
BRL64_12830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BRL64_12835	COG2706	6-phosphogluconolactonase activity
BRL64_12840	COG3339	Conserved Protein
BRL64_12845	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BRL64_12850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BRL64_12855	COG1696	Membrane protein involved in D-alanine export
BRL64_12905	COG0622	Phosphoesterase
BRL64_12910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BRL64_12915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BRL64_12920	COG5401	PFAM Sporulation and spore germination
BRL64_12925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BRL64_12930	COG1846	Transcriptional regulator
BRL64_12935	COG2197	response regulator
BRL64_12940	COG2851	Citrate transporter
BRL64_12945	COG0583	DNA-binding transcription factor activity
BRL64_12950	COG2828	Protein conserved in bacteria
BRL64_12960	COG0824	Thioesterase
BRL64_12965	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BRL64_12970	COG1053	succinate dehydrogenase
BRL64_12975	COG2009	succinate dehydrogenase
BRL64_12980	COG1719	4-vinyl reductase, 4VR
BRL64_12985	COG0527	aspartate kinase activity
BRL64_12990	COG0322	excinuclease ABC activity
BRL64_12995	COG3118	belongs to the thioredoxin family
BRL64_13000	COG3534	alpha-L-arabinofuranosidase
BRL64_13005	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BRL64_13010	COG2086	electron transfer activity
BRL64_13015	COG1024	Enoyl-CoA hydratase
BRL64_13020	COG1309	transcriptional regulator
BRL64_13025	COG0318	PFAM AMP-dependent synthetase and ligase
BRL64_13035	COG3766	membrane
BRL64_13040	COG1193	negative regulation of DNA recombination
BRL64_13045	COG1796	DNA polymerase
BRL64_13045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BRL64_13050	COG1286	toxin biosynthetic process
BRL64_13055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BRL64_13060	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BRL64_13065	COG0072	phenylalanine-tRNA ligase activity
BRL64_13065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRL64_13070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BRL64_13075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BRL64_13085	COG1966	Carbon starvation protein
BRL64_13090	COG1363	Peptidase, m42
BRL64_13100	COG3326	Membrane
BRL64_13105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BRL64_13110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BRL64_13115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BRL64_13120	COG1346	cytolysis
BRL64_13130	COG3279	Response regulator of the LytR AlgR family
BRL64_13135	COG3275	phosphorelay sensor kinase activity
BRL64_13150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BRL64_13160	COG0398	Pfam SNARE associated Golgi protein
BRL64_13165	COG1484	DNA-dependent DNA replication
BRL64_13170	COG3611	Membrane attachment protein
BRL64_13175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BRL64_13185	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BRL64_13190	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BRL64_13195	COG0237	dephospho-CoA kinase activity
BRL64_13200	COG1971	Probably functions as a manganese efflux pump
BRL64_13205	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BRL64_13210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRL64_13210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BRL64_13215	COG5002	protein histidine kinase activity
BRL64_13220	COG0745	RESPONSE REGULATOR receiver
BRL64_13225	COG0039	L-malate dehydrogenase activity
BRL64_13230	COG0538	isocitrate dehydrogenase activity
BRL64_13235	COG0372	Belongs to the citrate synthase family
BRL64_13240	COG2707	UPF0756 membrane protein
BRL64_13245	COG0628	permease
BRL64_13250	COG3030	protein affecting phage T7 exclusion by the F plasmid
BRL64_13260	COG0205	6-phosphofructokinase activity
BRL64_13265	COG0825	malonyl-CoA metabolic process
BRL64_13270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BRL64_13275	COG0281	malic enzyme
BRL64_13280	COG0587	DNA-directed DNA polymerase activity
BRL64_13300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BRL64_13310	COG4109	DRTGG domain
BRL64_13315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BRL64_13320	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_13330	COG0165	Argininosuccinate lyase
BRL64_13335	COG0137	argininosuccinate synthase activity
BRL64_13340	COG0521	Mo-molybdopterin cofactor biosynthetic process
BRL64_13345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BRL64_13350	COG0827	DNA restriction-modification system
BRL64_13355	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BRL64_13360	COG3874	Sporulation protein YtfJ
BRL64_13370	COG1714	RDD family
BRL64_13375	COG0616	signal peptide processing
BRL64_13380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BRL64_13390	COG3239	Fatty acid desaturase
BRL64_13395	COG4585	Histidine kinase
BRL64_13400	COG2197	response regulator
BRL64_13405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL64_13410	COG0745	RESPONSE REGULATOR receiver
BRL64_13415	COG0642	Histidine kinase
BRL64_13420	COG0772	Belongs to the SEDS family
BRL64_13425	COG1695	Transcriptional regulator
BRL64_13430	COG1136	(ABC) transporter
BRL64_13435	COG0577	efflux transmembrane transporter activity
BRL64_13440	COG0402	S-adenosylhomocysteine deaminase activity
BRL64_13445	COG1279	arginine transmembrane transporter activity
BRL64_13450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRL64_13460	COG0301	tRNA thio-modification
BRL64_13465	COG1104	cysteine desulfurase activity
BRL64_13470	COG1114	Component of the transport system for branched-chain amino acids
BRL64_13475	COG1114	Component of the transport system for branched-chain amino acids
BRL64_13480	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BRL64_13485	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BRL64_13490	COG1309	transcriptional regulator
BRL64_13495	COG1956	GAF domain-containing protein
BRL64_13500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BRL64_13530	COG1335	isochorismatase
BRL64_13535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BRL64_13540	COG2329	Antibiotic biosynthesis monooxygenase
BRL64_13545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BRL64_13550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BRL64_13555	COG0454	-acetyltransferase
BRL64_13560	COG0517	IMP dehydrogenase activity
BRL64_13565	COG0123	including yeast histone deacetylase and acetoin utilization protein
BRL64_13570	COG1609	Transcriptional regulator
BRL64_13575	COG1605	Chorismate mutase
BRL64_13575	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BRL64_13580	COG3118	belongs to the thioredoxin family
BRL64_13585	COG4980	gas vesicle protein
BRL64_13590	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BRL64_13595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BRL64_13600	COG1674	ftsk spoiiie
BRL64_13605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BRL64_13610	COG4848	Belongs to the UPF0354 family
BRL64_13615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_13630	COG1363	Peptidase, m42
BRL64_13635	COG5584	Small secreted protein
BRL64_13640	COG0281	malic enzyme
BRL64_13645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BRL64_13650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BRL64_13660	COG0510	thiamine kinase activity
BRL64_13670	COG1597	lipid kinase activity
BRL64_13680	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BRL64_13685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BRL64_13690	COG3340	Belongs to the peptidase S51 family
BRL64_13695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BRL64_13700	COG2252	PERMEase
BRL64_13705	COG1349	DNA-binding transcription factor activity
BRL64_13710	COG1187	pseudouridine synthase activity
BRL64_13715	COG2244	polysaccharide biosynthetic process
BRL64_13720	COG2081	HI0933 family
BRL64_13730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BRL64_13740	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BRL64_13745	COG5578	integral membrane protein
BRL64_13750	COG0673	inositol 2-dehydrogenase activity
BRL64_13755	COG1653	transport
BRL64_13760	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BRL64_13765	COG4209	transmembrane transport
BRL64_13770	COG2207	Transcriptional regulator
BRL64_13775	COG1733	regulation of RNA biosynthetic process
BRL64_13780	COG2814	Major facilitator Superfamily
BRL64_13785	COG0656	L-ascorbic acid biosynthetic process
BRL64_13790	COG1653	transport
BRL64_13795	COG0395	ABC-type sugar transport system, permease component
BRL64_13800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRL64_13805	COG1073	alpha beta
BRL64_13810	COG0495	leucyl-tRNA aminoacylation
BRL64_13820	COG2202	Pas domain
BRL64_13820	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_13825	COG2433	Pfam Transposase IS66
BRL64_13830	COG0577	efflux transmembrane transporter activity
BRL64_13835	COG1136	(ABC) transporter
BRL64_13845	COG1131	(ABC) transporter
BRL64_13850	COG1725	Transcriptional regulator
BRL64_13865	COG1242	4 iron, 4 sulfur cluster binding
BRL64_13870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BRL64_13880	COG2267	carboxylic ester hydrolase activity
BRL64_13885	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BRL64_13890	COG0367	asparagine synthase
BRL64_13895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BRL64_13900	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BRL64_13910	COG1506	peptidase
BRL64_13915	COG1233	COG1233 Phytoene dehydrogenase and related
BRL64_13935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BRL64_13940	COG1116	anion transmembrane transporter activity
BRL64_13945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BRL64_13950	COG0494	nUDIX hydrolase
BRL64_13955	COG2310	stress, protein
BRL64_13970	COG4824	toxin secretion phage lysis holin
BRL64_13980	COG0783	Belongs to the Dps family
BRL64_13995	COG1854	S-ribosylhomocysteine lyase activity
BRL64_14000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BRL64_14005	COG0288	reversible hydration of carbon dioxide
BRL64_14010	COG0803	Belongs to the bacterial solute-binding protein 9 family
BRL64_14010	COG3443	Belongs to the bacterial solute-binding protein 9 family
BRL64_14015	COG0254	rRNA binding
BRL64_14020	COG1271	oxidase subunit
BRL64_14025	COG1294	oxidase, subunit
BRL64_14040	COG4948	Mandelate Racemase Muconate Lactonizing
BRL64_14045	COG0318	PFAM AMP-dependent synthetase and ligase
BRL64_14050	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BRL64_14055	COG0596	Alpha beta hydrolase
BRL64_14060	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BRL64_14065	COG1169	isochorismate synthase
BRL64_14070	COG1575	Belongs to the MenA family. Type 1 subfamily
BRL64_14075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BRL64_14215	COG3859	Proton-coupled thiamine transporter YuaJ
BRL64_14225	COG1247	-acetyltransferase
BRL64_14230	COG2268	Band 7 protein
BRL64_14235	COG1585	Membrane protein implicated in regulation of membrane protease activity
BRL64_14240	COG2318	DinB family
BRL64_14245	COG1454	alcohol dehydrogenase
BRL64_14255	COG1510	regulation of RNA biosynthetic process
BRL64_14270	COG3409	Peptidoglycan-binding domain 1 protein
BRL64_14270	COG5632	N-Acetylmuramoyl-L-alanine amidase
BRL64_14305	COG3778	Protein conserved in bacteria
BRL64_14310	COG3299	homolog of phage Mu protein gp47
BRL64_14315	COG3628	GPW Gp25 family protein
BRL64_14325	COG4193	domain, Protein
BRL64_14330	COG1652	LysM domain
BRL64_14335	COG5280	Phage tail tape measure protein TP901
BRL64_14335	COG3953	SLT domain
BRL64_14335	COG5280	Phage tail tape measure protein TP901
BRL64_14335	COG3953	SLT domain
BRL64_14385	COG4653	Phage capsid family
BRL64_14390	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BRL64_14395	COG5518	Phage portal protein
BRL64_14400	COG1783	phage Terminase large subunit
BRL64_14405	COG5484	DNA packaging
BRL64_14410	COG1595	DNA-templated transcription, initiation
BRL64_14420	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BRL64_14435	COG1396	sequence-specific DNA binding
BRL64_14445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BRL64_14455	COG1968	undecaprenyl-diphosphatase activity
BRL64_14460	COG0628	permease
BRL64_14470	COG0673	inositol 2-dehydrogenase activity
BRL64_14475	COG0693	protein deglycase activity
BRL64_14480	COG0840	transmembrane signaling receptor activity
BRL64_14485	COG0840	transmembrane signaling receptor activity
BRL64_14490	COG0840	transmembrane signaling receptor activity
BRL64_14495	COG0840	transmembrane signaling receptor activity
BRL64_14510	COG2070	2-Nitropropane dioxygenase
BRL64_14515	COG0432	Pfam Uncharacterised protein family UPF0047
BRL64_14520	COG1253	flavin adenine dinucleotide binding
BRL64_14525	COG2738	Putative neutral zinc metallopeptidase
BRL64_14535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BRL64_14550	COG0166	Belongs to the GPI family
BRL64_14555	COG1979	alcohol dehydrogenase
BRL64_14560	COG1979	alcohol dehydrogenase
BRL64_14565	COG2155	Conserved Protein
BRL64_14570	COG1098	S1 RNA binding domain
BRL64_14575	COG0436	Aminotransferase
BRL64_14580	COG1522	sequence-specific DNA binding
BRL64_14585	COG2267	carboxylic ester hydrolase activity
BRL64_14595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BRL64_14600	COG2205	protein histidine kinase activity
BRL64_14615	COG5018	Exonuclease
BRL64_14620	COG2814	Major facilitator Superfamily
BRL64_14625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRL64_14630	COG3011	Protein conserved in bacteria
BRL64_14640	COG3290	protein histidine kinase activity
BRL64_14645	COG4565	transcriptional regulatory protein
BRL64_14670	COG3493	citrate carrier protein
BRL64_14680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BRL64_14680	COG2111	Na H antiporter
BRL64_14685	COG2111	Na H antiporter
BRL64_14690	COG1006	Multisubunit Na H antiporter MnhC subunit
BRL64_14695	COG0651	ATP synthesis coupled electron transport
BRL64_14700	COG1863	multisubunit Na H antiporter MnhE subunit
BRL64_14705	COG2212	antiporter activity
BRL64_14710	COG1320	monovalent cation:proton antiporter activity
BRL64_14715	COG2050	protein possibly involved in aromatic compounds catabolism
BRL64_14720	COG2197	response regulator
BRL64_14725	COG4585	Histidine kinase
BRL64_14735	COG0142	geranyltranstransferase activity
BRL64_14750	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BRL64_14755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BRL64_14760	COG1335	isochorismatase
BRL64_14765	COG5506	Protein of unknown function (DUF1694)
BRL64_14785	COG0628	permease
BRL64_14800	COG1418	mRNA catabolic process
BRL64_14805	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_14815	COG1511	domain protein
BRL64_14820	COG0433	COG0433 Predicted ATPase
BRL64_14820	COG1674	ftsk spoiiie
BRL64_14825	COG4499	WXG100 protein secretion system (Wss), protein YukC
BRL64_14830	COG5417	Belongs to the EsaB family
BRL64_14835	COG4842	Belongs to the WXG100 family
BRL64_14840	COG2508	Transcriptional regulator
BRL64_14840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BRL64_14845	COG0686	Belongs to the AlaDH PNT family
BRL64_14850	COG1268	BioY protein
BRL64_14855	COG4326	sporulation control protein
BRL64_14860	COG2056	Na+-H+ antiporter family
BRL64_14865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BRL64_14870	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BRL64_14875	COG3584	3D domain protein
BRL64_14885	COG1252	NADH dehydrogenase
BRL64_14890	COG0492	ferredoxin-NADP+ reductase activity
BRL64_14955	COG5280	Phage tail tape measure protein TP901
BRL64_14955	COG3953	SLT domain
BRL64_14995	COG0740	serine-type endopeptidase activity
BRL64_15090	COG4974	Belongs to the 'phage' integrase family
BRL64_15095	COG0316	Belongs to the HesB IscA family
BRL64_15100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BRL64_15105	COG4844	belongs to the
BRL64_15110	COG1252	NADH dehydrogenase
BRL64_15120	COG4837	Protein of unknown function (DUF1462)
BRL64_15125	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BRL64_15130	COG4946	Tricorn protease homolog
BRL64_15130	COG1506	peptidase
BRL64_15130	COG0823	Involved in the tonB-independent uptake of proteins
BRL64_15135	COG0083	homoserine kinase activity
BRL64_15140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BRL64_15145	COG0460	homoserine dehydrogenase
BRL64_15150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRL64_15155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BRL64_15160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BRL64_15165	COG0647	UMP catabolic process
BRL64_15170	COG2445	Protein of unknown function DUF86
BRL64_15175	COG4470	Protein conserved in bacteria
BRL64_15185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BRL64_15190	COG0739	heme binding
BRL64_15200	COG3377	Domain of unknown function (DUF1805)
BRL64_15205	COG0737	Belongs to the 5'-nucleotidase family
BRL64_15210	COG1801	Protein of unknown function DUF72
BRL64_15215	COG2508	Transcriptional regulator
BRL64_15220	COG2140	Oxalate decarboxylase
BRL64_15230	COG2814	Major facilitator Superfamily
BRL64_15235	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BRL64_15240	COG2356	endonuclease I
BRL64_15250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_15255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_15260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL64_15275	COG0561	phosphatase activity
BRL64_15285	COG0642	Histidine kinase
BRL64_15285	COG5002	protein histidine kinase activity
BRL64_15290	COG0745	RESPONSE REGULATOR receiver
BRL64_15295	COG2311	Membrane
BRL64_15305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BRL64_15320	COG0719	Fe-S assembly protein
BRL64_15325	COG0822	iron-sulfur transferase activity
BRL64_15330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BRL64_15335	COG0719	Fe-S assembly protein
BRL64_15340	COG0396	ATPase activity
BRL64_15345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BRL64_15350	COG1464	Belongs to the NlpA lipoprotein family
BRL64_15355	COG2011	ABC-type metal ion transport system permease component
BRL64_15360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BRL64_15370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_15375	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BRL64_15385	COG0509	glycine decarboxylation via glycine cleavage system
BRL64_15390	COG1393	Belongs to the ArsC family
BRL64_15395	COG1960	acyl-CoA dehydrogenase activity
BRL64_15400	COG0183	Belongs to the thiolase family
BRL64_15405	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRL64_15405	COG1024	Enoyl-CoA hydratase
BRL64_15415	COG5577	PFAM Coat F domain
BRL64_15425	COG1120	ATPase activity
BRL64_15435	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_15440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRL64_15445	COG0745	RESPONSE REGULATOR receiver
BRL64_15450	COG2205	protein histidine kinase activity
BRL64_15450	COG2770	Histidine kinase
BRL64_15455	COG1309	transcriptional regulator
BRL64_15465	COG0114	fumarate hydratase activity
BRL64_15470	COG0697	spore germination
BRL64_15475	COG0814	amino acid
BRL64_15490	COG2197	response regulator
BRL64_15495	COG4585	Histidine kinase
BRL64_15500	COG4758	membrane
BRL64_15510	COG1842	Phage shock protein A
BRL64_15515	COG4758	membrane
BRL64_15520	COG2096	Adenosyltransferase
BRL64_15525	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_15530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BRL64_15535	COG3395	kinase activity
BRL64_15540	COG2204	response regulator
BRL64_15555	COG1454	alcohol dehydrogenase
BRL64_15560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BRL64_15565	COG1120	ATPase activity
BRL64_15570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_15575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL64_15585	COG2721	sulfolactate sulfo-lyase activity
BRL64_15590	COG0246	Mannitol dehydrogenase
BRL64_15595	COG1609	Transcriptional regulator
BRL64_15600	COG1904	glucuronate isomerase
BRL64_15605	COG2205	protein histidine kinase activity
BRL64_15610	COG0745	RESPONSE REGULATOR receiver
BRL64_15615	COG1120	ATPase activity
BRL64_15620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_15625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_15630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL64_15635	COG0531	amino acid
BRL64_15650	COG1988	membrane-bound metal-dependent
BRL64_15655	COG1368	sulfuric ester hydrolase activity
BRL64_15660	COG0725	ABC transporter, periplasmic molybdate-binding protein
BRL64_15665	COG4149	molybdate abc transporter
BRL64_15670	COG0656	L-ascorbic acid biosynthetic process
BRL64_15675	COG1940	carbohydrate kinase activity
BRL64_15680	COG0025	NhaP-type Na H and K H
BRL64_15685	COG2860	membrane
BRL64_15690	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BRL64_15695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BRL64_15700	COG2217	Heavy metal translocating P-type atpase
BRL64_15705	COG1121	(ABC) transporter
BRL64_15710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BRL64_15715	COG0803	Belongs to the bacterial solute-binding protein 9 family
BRL64_15725	COG3226	Transcriptional regulator
BRL64_15730	COG0784	Response regulator, receiver
BRL64_15735	COG4191	Histidine kinase
BRL64_15740	COG1027	Aspartate ammonia-lyase
BRL64_15750	COG2217	Heavy metal translocating P-type atpase
BRL64_15755	COG2608	mercury ion transmembrane transporter activity
BRL64_15760	COG1937	Protein conserved in bacteria
BRL64_15770	COG3706	GGDEF domain
BRL64_15770	COG0745	RESPONSE REGULATOR receiver
BRL64_15795	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BRL64_15800	COG0557	exoribonuclease II activity
BRL64_15805	COG1647	Serine aminopeptidase, S33
BRL64_15810	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BRL64_15815	COG2002	toxin-antitoxin pair type II binding
BRL64_15820	COG1476	TRANSCRIPTIONal
BRL64_15825	COG1396	sequence-specific DNA binding
BRL64_15830	COG1396	sequence-specific DNA binding
BRL64_15835	COG1733	regulation of RNA biosynthetic process
BRL64_15840	COG1174	glycine betaine transport
BRL64_15845	COG1732	Glycine betaine
BRL64_15850	COG1174	glycine betaine transport
BRL64_15855	COG1125	glycine betaine transport
BRL64_15855	COG0517	IMP dehydrogenase activity
BRL64_15860	COG1510	regulation of RNA biosynthetic process
BRL64_15865	COG2095	MarC family integral membrane protein
BRL64_15875	COG0456	acetyltransferase
BRL64_15895	COG1122	ATPase activity
BRL64_15905	COG0148	phosphopyruvate hydratase activity
BRL64_15910	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BRL64_15915	COG0149	triose-phosphate isomerase activity
BRL64_15920	COG0126	phosphoglycerate kinase activity
BRL64_15925	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BRL64_15930	COG2390	Transcriptional regulator
BRL64_15940	COG0833	amino acid
BRL64_15945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BRL64_15950	COG3829	transcription factor binding
BRL64_15955	COG2186	Transcriptional regulator
BRL64_15960	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BRL64_15970	COG0534	Mate efflux family protein
BRL64_15980	COG0444	Belongs to the ABC transporter superfamily
BRL64_15985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BRL64_15990	COG0601	transmembrane transport
BRL64_15995	COG0747	negative chemotaxis
BRL64_16000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BRL64_16005	COG0110	maltose O-acetyltransferase activity
BRL64_16010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BRL64_16015	COG2244	polysaccharide biosynthetic process
BRL64_16020	COG5039	Polysaccharide pyruvyl transferase
BRL64_16025	COG1216	Glycosyl transferase, family 2
BRL64_16035	COG0438	transferase activity, transferring glycosyl groups
BRL64_16040	COG1215	transferase activity, transferring glycosyl groups
BRL64_16045	COG0438	transferase activity, transferring glycosyl groups
BRL64_16050	COG1086	Polysaccharide biosynthesis protein
BRL64_16055	COG0489	protein tyrosine kinase activity
BRL64_16060	COG3944	biosynthesis protein
BRL64_16065	COG1396	sequence-specific DNA binding
BRL64_16075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL64_16080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_16085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_16090	COG0726	polysaccharide deacetylase
BRL64_16115	COG0601	transmembrane transport
BRL64_16120	COG0747	negative chemotaxis
BRL64_16125	COG1819	glycosyl
BRL64_16140	COG0740	serine-type endopeptidase activity
BRL64_16145	COG1611	Belongs to the LOG family
BRL64_16150	COG1694	Mazg nucleotide pyrophosphohydrolase
BRL64_16155	COG0659	secondary active sulfate transmembrane transporter activity
BRL64_16160	COG0288	reversible hydration of carbon dioxide
BRL64_16165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BRL64_16175	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BRL64_16180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_16185	COG1481	regulation of sporulation
BRL64_16190	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BRL64_16195	COG1660	Displays ATPase and GTPase activities
BRL64_16200	COG1051	belongs to the nudix hydrolase family
BRL64_16205	COG0492	ferredoxin-NADP+ reductase activity
BRL64_16210	COG3883	PFAM NLP P60 protein
BRL64_16210	COG0791	NLP P60 protein
BRL64_16215	COG0457	Tetratricopeptide repeat
BRL64_16220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BRL64_16220	COG0140	phosphoribosyl-ATP diphosphatase activity
BRL64_16225	COG0107	imidazoleglycerol-phosphate synthase activity
BRL64_16230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BRL64_16235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BRL64_16240	COG0131	Imidazoleglycerol-phosphate dehydratase
BRL64_16245	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BRL64_16250	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BRL64_16255	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BRL64_16260	COG4990	cell redox homeostasis
BRL64_16270	COG2910	NAD(P)H-binding
BRL64_16275	COG1959	2 iron, 2 sulfur cluster binding
BRL64_16280	COG0110	maltose O-acetyltransferase activity
BRL64_16285	COG0546	phosphoglycolate phosphatase activity
BRL64_16290	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BRL64_16300	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BRL64_16305	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BRL64_16310	COG0363	glucosamine-6-phosphate deaminase activity
BRL64_16320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BRL64_16325	COG1950	PFAM Membrane protein of
BRL64_16330	COG1983	PspC domain protein
BRL64_16335	COG3595	metallopeptidase activity
BRL64_16350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BRL64_16360	COG4897	Protein conserved in bacteria
BRL64_16370	COG3848	Pyruvate phosphate dikinase
BRL64_16370	COG0574	Belongs to the PEP-utilizing enzyme family
BRL64_16375	COG1309	transcriptional regulator
BRL64_16380	COG2814	Major facilitator Superfamily
BRL64_16395	COG0745	RESPONSE REGULATOR receiver
BRL64_16400	COG5002	protein histidine kinase activity
BRL64_16405	COG1113	amino acid transport
BRL64_16410	COG0778	Nitroreductase
BRL64_16415	COG1733	regulation of RNA biosynthetic process
BRL64_16420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRL64_16430	COG3409	Peptidoglycan-binding domain 1 protein
BRL64_16430	COG0793	Belongs to the peptidase S41A family
BRL64_16435	COG0730	response to heat
BRL64_16440	COG0791	NLP P60 protein
BRL64_16440	COG3883	PFAM NLP P60 protein
BRL64_16445	COG2177	Part of the ABC transporter FtsEX involved in
BRL64_16450	COG2884	Cell division ATP-binding protein ftsE
BRL64_16455	COG2010	Cytochrome c
BRL64_16460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BRL64_16475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BRL64_16480	COG0653	protein targeting
BRL64_16485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BRL64_16490	COG0840	transmembrane signaling receptor activity
BRL64_16505	COG1516	flagellar protein fliS
BRL64_16510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BRL64_16515	COG1334	flagellar protein FlaG
BRL64_16520	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BRL64_16525	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BRL64_16535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BRL64_16540	COG4786	Flagellar basal body rod
BRL64_16540	COG1256	bacterial-type flagellum assembly
BRL64_16545	COG3418	PFAM FlgN family protein
BRL64_16560	COG1040	competence protein
BRL64_16570	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BRL64_16575	COG1307	EDD domain protein, DegV family
BRL64_16580	COG2197	response regulator
BRL64_16585	COG4585	Histidine kinase
BRL64_16590	COG1739	Uncharacterized protein family UPF0029
BRL64_16595	COG1316	TRANSCRIPTIONal
BRL64_16600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BRL64_16605	COG0438	transferase activity, transferring glycosyl groups
BRL64_16610	COG1215	transferase activity, transferring glycosyl groups
BRL64_16615	COG3206	protein involved in exopolysaccharide biosynthesis
BRL64_16620	COG3307	-O-antigen
BRL64_16625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BRL64_16630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BRL64_16635	COG0297	glycogen (starch) synthase activity
BRL64_16635	COG0438	transferase activity, transferring glycosyl groups
BRL64_16640	COG2244	polysaccharide biosynthetic process
BRL64_16660	COG0860	N-Acetylmuramoyl-L-alanine amidase
BRL64_16660	COG2247	cell wall binding repeat
BRL64_16665	COG2247	cell wall binding repeat
BRL64_16665	COG2385	sporulation resulting in formation of a cellular spore
BRL64_16675	COG1316	TRANSCRIPTIONal
BRL64_16680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BRL64_16685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BRL64_16690	COG1134	teichoic acid transport
BRL64_16695	COG1682	transport, permease protein
BRL64_16700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL64_16705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL64_16715	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BRL64_16720	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BRL64_16725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL64_16730	COG4193	domain, Protein
BRL64_16735	COG1482	cell wall glycoprotein biosynthetic process
BRL64_16745	COG1175	transmembrane transport
BRL64_16750	COG1653	transport
BRL64_16755	COG2197	response regulator
BRL64_16760	COG2972	Histidine kinase
BRL64_16770	COG0454	-acetyltransferase
BRL64_16775	COG0800	Aldolase
BRL64_16780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRL64_16785	COG1609	Transcriptional regulator
BRL64_16790	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BRL64_16795	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_16800	COG0697	spore germination
BRL64_16805	COG0814	amino acid
BRL64_16815	COG1216	Glycosyl transferase, family 2
BRL64_16820	COG2814	Major facilitator Superfamily
BRL64_16825	COG1316	TRANSCRIPTIONal
BRL64_16830	COG0561	phosphatase activity
BRL64_16835	COG0791	NLP P60 protein
BRL64_16840	COG2843	Capsule synthesis protein
BRL64_16850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BRL64_16855	COG0697	spore germination
BRL64_16870	COG1609	Transcriptional regulator
BRL64_16875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BRL64_16880	COG1869	D-ribose catabolic process
BRL64_16885	COG1129	ABC transporter
BRL64_16890	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRL64_16895	COG1879	ABC-type sugar transport system periplasmic component
BRL64_16900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BRL64_16905	COG0583	DNA-binding transcription factor activity
BRL64_16910	COG0028	Belongs to the TPP enzyme family
BRL64_16915	COG3527	Alpha-acetolactate decarboxylase
BRL64_16920	COG1522	sequence-specific DNA binding
BRL64_16925	COG2059	Chromate
BRL64_16930	COG2059	Chromate
BRL64_16935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BRL64_16940	COG4715	Zinc finger, swim domain protein
BRL64_16945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BRL64_16950	COG2202	Pas domain
BRL64_16950	COG1366	Belongs to the anti-sigma-factor antagonist family
BRL64_16955	COG0561	phosphatase activity
BRL64_16970	COG1970	mechanosensitive ion channel activity
BRL64_16975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BRL64_16980	COG0457	Tetratricopeptide repeat
BRL64_16985	COG4786	Flagellar basal body rod
BRL64_16990	COG4786	Flagellar basal body rod
BRL64_16995	COG1077	Cell shape determining protein MreB Mrl
BRL64_17000	COG1609	Transcriptional regulator
BRL64_17005	COG1846	Transcriptional regulator
BRL64_17010	COG2814	Major facilitator Superfamily
BRL64_17015	COG0671	phosphoesterase, PA-phosphatase related
BRL64_17020	COG0477	Major facilitator Superfamily
BRL64_17025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL64_17035	COG1126	abc transporter atp-binding protein
BRL64_17040	COG0004	ammonium transporteR
BRL64_17045	COG0347	Belongs to the P(II) protein family
BRL64_17050	COG0739	heme binding
BRL64_17055	COG1247	-acetyltransferase
BRL64_17070	COG0523	cobalamin synthesis protein
BRL64_17075	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BRL64_17080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BRL64_17085	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BRL64_17095	COG0243	molybdopterin cofactor binding
BRL64_17100	COG2304	oxidoreductase activity
BRL64_17105	COG2304	oxidoreductase activity
BRL64_17110	COG2385	sporulation resulting in formation of a cellular spore
BRL64_17115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BRL64_17125	COG4836	Membrane
BRL64_17135	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BRL64_17140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BRL64_17145	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BRL64_17150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BRL64_17155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BRL64_17160	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BRL64_17165	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BRL64_17170	COG0356	it plays a direct role in the translocation of protons across the membrane
BRL64_17180	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BRL64_17185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BRL64_17190	COG4475	Protein of unknown function (DUF436)
BRL64_17195	COG0698	ribose 5-phosphate isomerase
BRL64_17200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BRL64_17205	COG1971	Probably functions as a manganese efflux pump
BRL64_17210	COG0009	L-threonylcarbamoyladenylate synthase
BRL64_17215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BRL64_17230	COG2890	protein-(glutamine-N5) methyltransferase activity
BRL64_17235	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BRL64_17240	COG0789	Transcriptional regulator
BRL64_17245	COG0679	Auxin Efflux Carrier
BRL64_17250	COG0281	malic enzyme
BRL64_17255	COG1435	thymidine kinase activity
BRL64_17260	COG0254	rRNA binding
BRL64_17265	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BRL64_17270	COG1494	fructose-1,6-bisphosphatase
BRL64_17275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BRL64_17280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BRL64_17285	COG0191	fructose-bisphosphate aldolase activity
BRL64_17290	COG2204	response regulator
BRL64_17295	COG4821	SIS domain
BRL64_17300	COG0504	CTP synthase activity
BRL64_17305	COG3343	RNA polymerase activity
BRL64_17315	COG1960	acyl-CoA dehydrogenase activity
BRL64_17320	COG1960	acyl-CoA dehydrogenase activity
BRL64_17325	COG1250	3-hydroxyacyl-CoA dehydrogenase
BRL64_17330	COG0183	Belongs to the thiolase family
BRL64_17335	COG2181	nitrate reductase activity
BRL64_17335	COG0247	lactate metabolic process
BRL64_17340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRL64_17345	COG4294	response to UV
BRL64_17355	COG1619	proteins homologs of microcin C7 resistance protein MccF
BRL64_17360	COG1132	(ABC) transporter
BRL64_17365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BRL64_17370	COG1619	proteins homologs of microcin C7 resistance protein MccF
BRL64_17375	COG0018	arginyl-trna synthetase
BRL64_17380	COG4506	Protein conserved in bacteria
BRL64_17390	COG0010	Belongs to the arginase family
BRL64_17395	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BRL64_17400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BRL64_17410	COG1994	Peptidase M50
BRL64_17415	COG1942	4-Oxalocrotonate Tautomerase
BRL64_17425	COG3465	dGTPase activity
BRL64_17430	COG1078	dGTPase activity
BRL64_17435	COG4844	belongs to the
BRL64_17485	COG5444	nuclease activity
BRL64_17515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BRL64_17525	COG0280	phosphate acetyltransferase
BRL64_17535	COG1073	alpha beta
BRL64_17540	COG1522	sequence-specific DNA binding
BRL64_17545	COG2814	Major facilitator Superfamily
BRL64_17550	COG0077	Prephenate dehydratase
BRL64_17560	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_17565	COG0151	Belongs to the GarS family
BRL64_17570	COG0436	Aminotransferase
BRL64_17575	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_17580	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BRL64_17585	COG1091	dTDP-4-dehydrorhamnose reductase activity
BRL64_17590	COG1088	dTDP-glucose 4,6-dehydratase activity
BRL64_17595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BRL64_17600	COG3980	spore coat polysaccharide biosynthesis protein
BRL64_17605	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BRL64_17610	COG2089	acid synthase
BRL64_17615	COG0456	acetyltransferase
BRL64_17620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BRL64_17625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BRL64_17630	COG0463	Glycosyl transferase, family 2
BRL64_17650	COG2363	Small membrane protein
BRL64_17655	COG2233	PERMEase
BRL64_17665	COG1012	belongs to the aldehyde dehydrogenase family
BRL64_17670	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BRL64_17675	COG1216	Glycosyl transferase, family 2
BRL64_17685	COG0351	phosphomethylpyrimidine kinase
BRL64_17700	COG1621	beta-fructofuranosidase activity
BRL64_17705	COG1263	PTS System
BRL64_17705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_17710	COG3711	transcriptional antiterminator
BRL64_17720	COG1404	Belongs to the peptidase S8 family
BRL64_17725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BRL64_17730	COG0778	Nitroreductase
BRL64_17735	COG0772	Belongs to the SEDS family
BRL64_17745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BRL64_17750	COG1845	cytochrome c oxidase, subunit III
BRL64_17755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BRL64_17760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BRL64_17770	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BRL64_17775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BRL64_17780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BRL64_17795	COG2246	polysaccharide biosynthetic process
BRL64_17820	COG0457	Tetratricopeptide repeat
BRL64_17835	COG3162	membrane
BRL64_17840	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BRL64_17855	COG0352	thiamine-phosphate diphosphorylase activity
BRL64_17860	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BRL64_17865	COG0583	DNA-binding transcription factor activity
BRL64_17870	COG1380	Effector of murein hydrolase LrgA
BRL64_17875	COG1346	cytolysis
BRL64_17880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BRL64_17885	COG0346	lactoylglutathione lyase activity
BRL64_17895	COG0765	amino acid transport
BRL64_17900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BRL64_17905	COG0457	Tetratricopeptide repeat
BRL64_17910	COG2357	RelA SpoT domain protein
BRL64_17915	COG1172	Belongs to the binding-protein-dependent transport system permease family
BRL64_17920	COG1129	ABC transporter
BRL64_17930	COG3420	alginic acid biosynthetic process
BRL64_17935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BRL64_17950	COG1486	melibiose metabolic process
BRL64_17955	COG1447	Phosphotransferase system cellobiose-specific component IIA
BRL64_17960	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BRL64_17965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BRL64_17970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_17970	COG3711	transcriptional antiterminator
BRL64_17985	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BRL64_18000	COG1595	DNA-templated transcription, initiation
BRL64_18005	COG3866	Pectate lyase
BRL64_18010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BRL64_18015	COG4988	ABC transporter
BRL64_18020	COG1294	oxidase, subunit
BRL64_18025	COG1271	oxidase subunit
BRL64_18035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BRL64_18045	COG4509	Sortase family
BRL64_18070	COG5386	Cell surface protein
BRL64_18075	COG5386	Cell surface protein
BRL64_18080	COG1733	regulation of RNA biosynthetic process
BRL64_18085	COG2514	catechol 2,3-dioxygenase activity
BRL64_18090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BRL64_18090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BRL64_18095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRL64_18095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BRL64_18105	COG0726	polysaccharide deacetylase
BRL64_18110	COG1447	Phosphotransferase system cellobiose-specific component IIA
BRL64_18115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BRL64_18120	COG2723	6-phospho-beta-galactosidase activity
BRL64_18125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BRL64_18130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BRL64_18130	COG3711	transcriptional antiterminator
BRL64_18155	COG1757	Na H antiporter
BRL64_18160	COG1027	Aspartate ammonia-lyase
BRL64_18165	COG0252	asparaginase activity
BRL64_18170	COG1396	sequence-specific DNA binding
BRL64_18195	COG4842	Belongs to the WXG100 family
BRL64_18200	COG2195	Cleaves the N-terminal amino acid of tripeptides
BRL64_18215	COG1737	Transcriptional regulator
BRL64_18220	COG2084	Dehydrogenase
BRL64_18230	COG2610	gluconate transmembrane transporter activity
BRL64_18235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BRL64_18240	COG2850	peptidyl-arginine hydroxylation
BRL64_18245	COG2226	methyltransferase
BRL64_18260	COG0477	Major facilitator Superfamily
BRL64_18265	COG0367	asparagine synthase
BRL64_18270	COG2723	6-phospho-beta-galactosidase activity
BRL64_18275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_18275	COG2190	(PTS) system
BRL64_18275	COG1263	PTS System
BRL64_18280	COG3711	transcriptional antiterminator
BRL64_18285	COG3878	Protein conserved in bacteria
BRL64_18295	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BRL64_18300	COG1122	ATPase activity
BRL64_18305	COG4721	ABC-type cobalt transport system, permease component
BRL64_18310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BRL64_18335	COG3291	Pkd domain containing protein
BRL64_18335	COG4412	M6 family metalloprotease domain protein
BRL64_18340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BRL64_18345	COG0778	Nitroreductase
BRL64_18350	COG1846	Transcriptional regulator
BRL64_18355	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BRL64_18360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BRL64_18365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BRL64_18370	COG2390	Transcriptional regulator
BRL64_18380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BRL64_18380	COG2755	lipolytic protein G-D-S-L family
BRL64_18400	COG0561	phosphatase activity
BRL64_18405	COG0789	Transcriptional regulator
BRL64_18410	COG0673	inositol 2-dehydrogenase activity
BRL64_18415	COG0840	transmembrane signaling receptor activity
BRL64_18420	COG1113	amino acid transport
BRL64_18425	COG4335	DNA alkylation repair
BRL64_18435	COG1070	Carbohydrate kinase
BRL64_18440	COG1737	Transcriptional regulator
BRL64_18460	COG0583	DNA-binding transcription factor activity
BRL64_18465	COG1609	Transcriptional regulator
BRL64_18470	COG2182	Extracellular solute-binding protein
BRL64_18475	COG1175	transmembrane transport
BRL64_18480	COG3833	ABC-type maltose transport systems, permease component
BRL64_18490	COG1874	Beta-galactosidase
BRL64_18495	COG2851	Citrate transporter
BRL64_18505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BRL64_18510	COG1131	(ABC) transporter
BRL64_18520	COG2824	Alkylphosphonate utilization operon protein PhnA
BRL64_18525	COG1929	Belongs to the glycerate kinase type-1 family
BRL64_18530	COG2610	gluconate transmembrane transporter activity
BRL64_18535	COG3835	regulator
BRL64_18540	COG1309	transcriptional regulator
BRL64_18545	COG2814	Major facilitator Superfamily
BRL64_18555	COG1136	(ABC) transporter
BRL64_18555	COG0577	efflux transmembrane transporter activity
BRL64_18565	COG0457	Tetratricopeptide repeat
BRL64_18570	COG3711	transcriptional antiterminator
BRL64_18575	COG2723	6-phospho-beta-galactosidase activity
BRL64_18580	COG2190	(PTS) system
BRL64_18580	COG1263	PTS System
BRL64_18580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BRL64_18615	COG1113	amino acid transport
BRL64_18630	COG2814	Major facilitator Superfamily
BRL64_18635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BRL64_18640	COG2814	Major facilitator Superfamily
BRL64_18655	COG5444	nuclease activity
BRL64_18665	COG2723	6-phospho-beta-galactosidase activity
BRL64_18675	COG2188	Transcriptional regulator
BRL64_18685	COG0384	phenazine biosynthesis protein PhzF
BRL64_18690	COG0583	DNA-binding transcription factor activity
BRL64_18710	COG2814	Major facilitator Superfamily
BRL64_18715	COG0640	Transcriptional regulator
BRL64_18740	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BRL64_18750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BRL64_18760	COG4720	Psort location CytoplasmicMembrane, score
BRL64_18780	COG0456	acetyltransferase
BRL64_18785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BRL64_18790	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BRL64_18795	COG4853	Protein conserved in bacteria
BRL64_18800	COG4863	YycH protein
BRL64_18805	COG5002	protein histidine kinase activity
BRL64_18810	COG0745	RESPONSE REGULATOR receiver
BRL64_18835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BRL64_18845	COG2311	Membrane
BRL64_18850	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BRL64_18855	COG0346	lactoylglutathione lyase activity
BRL64_18860	COG0305	Participates in initiation and elongation during chromosome replication
BRL64_18880	COG2819	hydrolase of the alpha beta superfamily
BRL64_18885	COG1028	Short-chain dehydrogenase reductase Sdr
BRL64_18890	COG1169	isochorismate synthase
BRL64_18895	COG1021	2,3-dihydroxybenzoate-AMP ligase
BRL64_18900	COG1535	isochorismatase
BRL64_18900	COG3433	isochorismatase activity
BRL64_18905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BRL64_18910	COG3251	PFAM MbtH domain protein
BRL64_18915	COG2207	Transcriptional regulator
BRL64_18915	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL64_18920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BRL64_18925	COG2819	hydrolase of the alpha beta superfamily
BRL64_18930	COG3093	addiction module antidote protein HigA
BRL64_18935	COG2807	transmembrane transport
BRL64_18940	COG0359	binds to the 23S rRNA
BRL64_18945	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BRL64_18950	COG4241	membrane
BRL64_18955	COG1227	inorganic diphosphatase activity
BRL64_18965	COG1595	DNA-templated transcription, initiation
BRL64_18975	COG0753	catalase activity
BRL64_18980	COG0655	NAD(P)H dehydrogenase (quinone) activity
BRL64_18985	COG0400	carboxylic ester hydrolase activity
BRL64_18990	COG0346	lactoylglutathione lyase activity
BRL64_18995	COG1174	glycine betaine transport
BRL64_19000	COG0517	IMP dehydrogenase activity
BRL64_19000	COG1125	glycine betaine transport
BRL64_19005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BRL64_19010	COG0629	single-stranded DNA binding
BRL64_19015	COG0360	Binds together with S18 to 16S ribosomal RNA
BRL64_19020	COG0012	GTP binding
BRL64_19025	COG4481	Protein conserved in bacteria
BRL64_19040	COG3949	Membrane
BRL64_19050	COG1475	DNA binding
BRL64_19055	COG1192	Involved in chromosome partitioning
BRL64_19065	COG1475	DNA binding
BRL64_19070	COG0357	Ribosomal RNA small subunit methyltransferase G
BRL64_19075	COG0445	tRNA wobble uridine modification
BRL64_19080	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BRL64_19085	COG1847	R3H domain protein
BRL64_19090	COG0706	membrane insertase activity
BRL64_19095	COG0594	ribonuclease P activity