locus-tag	class	description
FX981_00002	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FX981_00003	COG0284	orotidine-5'-phosphate decarboxylase activity
FX981_00004	COG0167	dihydroorotate dehydrogenase activity
FX981_00005	COG0543	2 iron, 2 sulfur cluster binding
FX981_00006	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FX981_00007	COG0505	Belongs to the CarA family
FX981_00008	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FX981_00009	COG0540	Belongs to the ATCase OTCase family
FX981_00010	COG2233	PERMEase
FX981_00011	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FX981_00012	COG0564	pseudouridine synthase activity
FX981_00013	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FX981_00014	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FX981_00015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FX981_00016	COG3599	regulation of cell shape
FX981_00017	COG2302	S4 RNA-binding domain
FX981_00018	COG0762	integral membrane protein
FX981_00019	COG1799	cell septum assembly
FX981_00020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FX981_00022	COG1873	PFAM PRC-barrel domain
FX981_00023	COG1119	ATPase activity
FX981_00025	COG3732	PTS system glucitol sorbitol-specific
FX981_00026	COG3730	PTS system glucitol sorbitol-specific
FX981_00029	COG2390	Transcriptional regulator
FX981_00030	COG1191	sigma factor activity
FX981_00031	COG1191	sigma factor activity
FX981_00033	COG1404	Belongs to the peptidase S8 family
FX981_00033	COG4412	M6 family metalloprotease domain protein
FX981_00034	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FX981_00035	COG0849	cell division
FX981_00036	COG3856	small basic protein
FX981_00037	COG3879	Bacterial protein of unknown function (DUF881)
FX981_00038	COG3879	Bacterial protein of unknown function (DUF881)
FX981_00039	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FX981_00040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FX981_00041	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FX981_00042	COG0772	Belongs to the SEDS family
FX981_00043	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FX981_00044	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FX981_00045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FX981_00046	COG0768	penicillin binding
FX981_00048	COG4839	cell division protein FtsL
FX981_00049	COG0275	rRNA processing
FX981_00050	COG2001	Belongs to the MraZ family
FX981_00051	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FX981_00052	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FX981_00053	COG0454	-acetyltransferase
FX981_00055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FX981_00056	COG1399	metal-binding, possibly nucleic acid-binding protein
FX981_00058	COG3480	Lon protease (S16) C-terminal proteolytic domain
FX981_00059	COG1752	Esterase of the alpha-beta hydrolase superfamily
FX981_00060	COG3314	Sporulation integral membrane protein YlbJ
FX981_00061	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FX981_00062	COG0742	ribosomal rna small subunit methyltransferase
FX981_00063	COG4471	UPF0298 protein
FX981_00064	COG3679	Belongs to the UPF0342 family
FX981_00068	COG2340	Cysteine-rich secretory protein family
FX981_00069	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FX981_00071	COG2801	Transposase and inactivated derivatives
FX981_00073	COG3336	cytochrome c oxidase
FX981_00074	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FX981_00075	COG1845	cytochrome c oxidase, subunit III
FX981_00076	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FX981_00077	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FX981_00077	COG2010	Cytochrome c
FX981_00078	COG0109	protoheme IX farnesyltransferase activity
FX981_00079	COG1612	heme a metabolic process
FX981_00081	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FX981_00082	COG0772	Belongs to the SEDS family
FX981_00083	COG4838	Belongs to the UPF0358 family
FX981_00084	COG2066	Belongs to the glutaminase family
FX981_00085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FX981_00086	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FX981_00088	COG4896	Protein conserved in bacteria
FX981_00094	COG1595	DNA-templated transcription, initiation
FX981_00097	COG0483	inositol monophosphate 1-phosphatase activity
FX981_00099	COG4493	Belongs to the UPF0637 family
FX981_00100	COG4476	Belongs to the UPF0223 family
FX981_00101	COG1982	Orn Lys Arg decarboxylase major
FX981_00102	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_00103	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FX981_00104	COG0508	dehydrogenase complex catalyzes the overall conversion of
FX981_00105	COG0022	dehydrogenase e1 component
FX981_00106	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FX981_00109	COG0242	peptide deformylase activity
FX981_00110	COG0561	phosphatase activity
FX981_00112	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FX981_00113	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FX981_00114	COG0569	domain protein
FX981_00115	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FX981_00115	COG2105	PFAM AIG2 family protein
FX981_00116	COG3852	Histidine kinase
FX981_00117	COG2002	toxin-antitoxin pair type II binding
FX981_00118	COG1077	Cell shape determining protein MreB Mrl
FX981_00120	COG2309	aminopeptidase activity
FX981_00121	COG0488	(ABC) transporter
FX981_00123	COG0681	Belongs to the peptidase S26 family
FX981_00124	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_00124	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_00124	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_00125	COG1105	Belongs to the carbohydrate kinase PfkB family
FX981_00126	COG1349	DNA-binding transcription factor activity
FX981_00127	COG0577	efflux transmembrane transporter activity
FX981_00128	COG1136	(ABC) transporter
FX981_00129	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FX981_00132	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FX981_00133	COG0314	molybdopterin synthase activity
FX981_00134	COG1763	Mo-molybdopterin cofactor biosynthetic process
FX981_00135	COG0303	'Molybdopterin
FX981_00136	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FX981_00137	COG0746	molybdenum cofactor guanylyltransferase activity
FX981_00140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_00141	COG0450	alkyl hydroperoxide reductase
FX981_00142	COG0668	transmembrane transport
FX981_00144	COG1473	amidohydrolase
FX981_00145	COG2171	N-acyltransferase activity
FX981_00146	COG0716	FMN binding
FX981_00148	COG0716	FMN binding
FX981_00149	COG0583	DNA-binding transcription factor activity
FX981_00150	COG0517	IMP dehydrogenase activity
FX981_00152	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FX981_00153	COG4703	Protein of unknown function (DUF1797)
FX981_00154	COG3546	catalase activity
FX981_00155	COG2200	EAL domain
FX981_00156	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_00157	COG1408	metallophosphoesterase
FX981_00158	COG1376	ErfK ybiS ycfS ynhG family protein
FX981_00159	COG2814	Major facilitator Superfamily
FX981_00161	COG0697	spore germination
FX981_00162	COG2207	Transcriptional regulator
FX981_00162	COG1917	Cupin 2, conserved barrel domain protein
FX981_00164	COG0457	Tetratricopeptide repeat
FX981_00177	COG0305	Participates in initiation and elongation during chromosome replication
FX981_00179	COG0784	Response regulator, receiver
FX981_00179	COG0835	chemotaxis
FX981_00181	COG1714	RDD family
FX981_00183	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FX981_00184	COG0436	Aminotransferase
FX981_00185	COG4191	Histidine kinase
FX981_00186	COG0768	penicillin binding
FX981_00187	COG2340	Cysteine-rich secretory protein family
FX981_00188	COG2084	Dehydrogenase
FX981_00190	COG0840	transmembrane signaling receptor activity
FX981_00191	COG1533	DNA photolyase activity
FX981_00193	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FX981_00194	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_00195	COG2190	(PTS) system
FX981_00195	COG1263	PTS System
FX981_00195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_00196	COG3711	transcriptional antiterminator
FX981_00197	COG1609	Transcriptional regulator
FX981_00198	COG0006	proline dipeptidase activity
FX981_00199	COG2217	Heavy metal translocating P-type atpase
FX981_00200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_00201	COG2244	polysaccharide biosynthetic process
FX981_00202	COG3773	Cell wall hydrolase
FX981_00204	COG4873	Protein conserved in bacteria
FX981_00207	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_00208	COG1733	regulation of RNA biosynthetic process
FX981_00209	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FX981_00210	COG0602	queuosine metabolic process
FX981_00211	COG0720	synthase
FX981_00212	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FX981_00213	COG3949	Membrane
FX981_00214	COG0542	response to heat
FX981_00216	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FX981_00217	COG1360	Flagellar Motor Protein
FX981_00218	COG1846	Transcriptional regulator
FX981_00219	COG3852	Histidine kinase
FX981_00221	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FX981_00222	COG0235	Class ii aldolase
FX981_00223	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FX981_00224	COG1850	ribulose-bisphosphate carboxylase activity
FX981_00225	COG0436	Aminotransferase
FX981_00226	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FX981_00227	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FX981_00229	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FX981_00230	COG5002	protein histidine kinase activity
FX981_00231	COG3594	Acyltransferase
FX981_00234	COG2323	membrane
FX981_00235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FX981_00236	COG0501	Belongs to the peptidase M48B family
FX981_00240	COG1191	sigma factor activity
FX981_00241	COG0861	Integral membrane protein TerC family
FX981_00242	COG0586	Pfam SNARE associated Golgi protein
FX981_00243	COG5001	Diguanylate cyclase
FX981_00243	COG3300	MHYT domain
FX981_00244	COG1846	Transcriptional regulator
FX981_00246	COG0789	Transcriptional regulator
FX981_00248	COG2239	Acts as a magnesium transporter
FX981_00250	COG3212	peptidase
FX981_00251	COG3212	peptidase
FX981_00252	COG5002	protein histidine kinase activity
FX981_00252	COG3850	Histidine kinase
FX981_00253	COG0745	RESPONSE REGULATOR receiver
FX981_00254	COG1404	Belongs to the peptidase S8 family
FX981_00255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FX981_00256	COG0590	tRNA wobble adenosine to inosine editing
FX981_00257	COG1764	response to oxidative stress
FX981_00258	COG1846	Transcriptional regulator
FX981_00259	COG1764	response to oxidative stress
FX981_00261	COG0457	Tetratricopeptide repeat
FX981_00262	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FX981_00263	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FX981_00264	COG0788	formyltetrahydrofolate deformylase activity
FX981_00266	COG2076	Multidrug Resistance protein
FX981_00267	COG2076	Multidrug Resistance protein
FX981_00270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FX981_00273	COG1695	Transcriptional regulator
FX981_00274	COG1607	acyl-coa hydrolase
FX981_00275	COG1834	amidinotransferase
FX981_00276	COG4608	Belongs to the ABC transporter superfamily
FX981_00277	COG0791	NLP P60 protein
FX981_00278	COG4948	Mandelate Racemase Muconate Lactonizing
FX981_00279	COG1619	proteins homologs of microcin C7 resistance protein MccF
FX981_00280	COG4166	transmembrane transport
FX981_00281	COG0444	Belongs to the ABC transporter superfamily
FX981_00282	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FX981_00283	COG0601	transmembrane transport
FX981_00284	COG2362	D-Aminopeptidase
FX981_00285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FX981_00286	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FX981_00287	COG0346	lactoylglutathione lyase activity
FX981_00288	COG0531	amino acid
FX981_00290	COG2390	Transcriptional regulator
FX981_00291	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_00292	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_00293	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FX981_00294	COG0508	dehydrogenase complex catalyzes the overall conversion of
FX981_00295	COG0508	dehydrogenase complex catalyzes the overall conversion of
FX981_00295	COG0022	dehydrogenase e1 component
FX981_00296	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FX981_00297	COG1063	alcohol dehydrogenase
FX981_00300	COG3775	system Galactitol-specific IIC component
FX981_00302	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FX981_00303	COG4208	sulfate ABC transporter
FX981_00305	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FX981_00306	COG0405	Gamma-glutamyltransferase
FX981_00308	COG1392	Phosphate transport regulator
FX981_00309	COG0306	phosphate transporter
FX981_00313	COG5632	N-Acetylmuramoyl-L-alanine amidase
FX981_00313	COG3409	Peptidoglycan-binding domain 1 protein
FX981_00314	COG2856	Zn peptidase
FX981_00315	COG4195	phage-related replication protein
FX981_00319	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FX981_00320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FX981_00324	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FX981_00328	COG0457	Tetratricopeptide repeat
FX981_00329	COG0457	Tetratricopeptide repeat
FX981_00331	COG2807	transmembrane transport
FX981_00332	COG0583	DNA-binding transcription factor activity
FX981_00336	COG0583	DNA-binding transcription factor activity
FX981_00337	COG3173	Aminoglycoside phosphotransferase
FX981_00341	COG0457	Tetratricopeptide repeat
FX981_00352	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FX981_00355	COG0825	malonyl-CoA metabolic process
FX981_00363	COG0626	cystathionine gamma-synthase activity
FX981_00364	COG0626	cystathionine gamma-synthase activity
FX981_00365	COG2382	esterase
FX981_00366	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FX981_00367	COG2153	protein acetylation
FX981_00369	COG0210	DNA helicase
FX981_00381	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FX981_00382	COG0351	phosphomethylpyrimidine kinase
FX981_00383	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FX981_00384	COG2022	thiamine diphosphate biosynthetic process
FX981_00385	COG2104	thiamine diphosphate biosynthetic process
FX981_00387	COG0352	thiamine-phosphate diphosphorylase activity
FX981_00388	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FX981_00389	COG0569	domain protein
FX981_00389	COG0475	glutathione-regulated potassium exporter activity
FX981_00390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FX981_00391	COG0564	pseudouridine synthase activity
FX981_00392	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FX981_00393	COG2357	RelA SpoT domain protein
FX981_00395	COG4116	CYTH
FX981_00396	COG0741	lytic transglycosylase activity
FX981_00397	COG2346	COG2346, Truncated hemoglobins
FX981_00400	COG1164	Oligoendopeptidase f
FX981_00402	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FX981_00403	COG4862	establishment of competence for transformation
FX981_00404	COG0861	Integral membrane protein TerC family
FX981_00405	COG1393	Belongs to the ArsC family
FX981_00406	COG0456	acetyltransferase
FX981_00408	COG4608	Belongs to the ABC transporter superfamily
FX981_00409	COG0444	Belongs to the ABC transporter superfamily
FX981_00410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FX981_00411	COG0601	transmembrane transport
FX981_00412	COG4166	transmembrane transport
FX981_00413	COG0180	Tryptophanyl-tRNA synthetase
FX981_00415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FX981_00416	COG0601	transmembrane transport
FX981_00418	COG4608	Belongs to the ABC transporter superfamily
FX981_00419	COG0444	Belongs to the ABC transporter superfamily
FX981_00420	COG5504	Zn-dependent protease
FX981_00421	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FX981_00422	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FX981_00425	COG1744	ABC transporter substrate-binding protein PnrA-like
FX981_00427	COG2267	carboxylic ester hydrolase activity
FX981_00429	COG2814	Major facilitator Superfamily
FX981_00431	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FX981_00432	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FX981_00433	COG0505	Belongs to the CarA family
FX981_00434	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FX981_00435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FX981_00437	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FX981_00438	COG2271	Major facilitator Superfamily
FX981_00439	COG0277	FAD linked oxidase domain protein
FX981_00440	COG2151	metal-sulfur cluster biosynthetic enzyme
FX981_00441	COG1073	alpha beta
FX981_00442	COG0561	phosphatase activity
FX981_00446	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FX981_00447	COG1307	EDD domain protein, DegV family
FX981_00448	COG0840	transmembrane signaling receptor activity
FX981_00450	COG2996	Protein conserved in bacteria
FX981_00451	COG1666	GTP binding
FX981_00452	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FX981_00452	COG0646	methionine synthase
FX981_00453	COG0646	methionine synthase
FX981_00453	COG1410	methionine synthase
FX981_00459	COG0076	glutamate decarboxylase activity
FX981_00465	COG2207	Transcriptional regulator
FX981_00465	COG1917	Cupin 2, conserved barrel domain protein
FX981_00466	COG0534	Mate efflux family protein
FX981_00467	COG1562	ergosterol biosynthetic process
FX981_00470	COG0367	asparagine synthase
FX981_00473	COG0179	Fumarylacetoacetate (FAA) hydrolase
FX981_00475	COG5337	Spore coat protein CotH
FX981_00483	COG1403	HNH endonuclease
FX981_00484	COG0419	ATPase involved in DNA repair
FX981_00485	COG0420	3'-5' exonuclease activity
FX981_00486	COG1074	ATP-dependent DNA helicase activity
FX981_00487	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FX981_00488	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FX981_00489	COG2259	Doxx family
FX981_00490	COG0501	Belongs to the peptidase M48B family
FX981_00492	COG3180	Ammonia monooxygenase
FX981_00493	COG0681	Belongs to the peptidase S26 family
FX981_00494	COG0398	Pfam SNARE associated Golgi protein
FX981_00496	COG1316	TRANSCRIPTIONal
FX981_00497	COG4607	ABC-type enterochelin transport system periplasmic component
FX981_00498	COG4604	ABC transporter, ATP-binding protein
FX981_00499	COG4605	iron ion homeostasis
FX981_00500	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_00501	COG2732	(Barnase) inhibitor
FX981_00502	COG2814	Major facilitator Superfamily
FX981_00503	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FX981_00505	COG4903	ComK protein
FX981_00507	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_00508	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FX981_00508	COG0723	plastoquinol--plastocyanin reductase activity
FX981_00509	COG0840	transmembrane signaling receptor activity
FX981_00510	COG0406	alpha-ribazole phosphatase activity
FX981_00511	COG1404	Belongs to the peptidase S8 family
FX981_00512	COG0501	Belongs to the peptidase M48B family
FX981_00514	COG0318	PFAM AMP-dependent synthetase and ligase
FX981_00515	COG0095	Lipoate-protein ligase
FX981_00516	COG1234	tRNA 3'-trailer cleavage
FX981_00518	COG1301	dicarboxylic acid transport
FX981_00519	COG1363	Peptidase, m42
FX981_00520	COG1511	domain protein
FX981_00521	COG1309	transcriptional regulator
FX981_00524	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FX981_00525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FX981_00526	COG2329	Antibiotic biosynthesis monooxygenase
FX981_00528	COG1473	amidohydrolase
FX981_00530	COG4473	ABC transporter
FX981_00531	COG1131	(ABC) transporter
FX981_00532	COG0537	adenosine 5'-monophosphoramidase activity
FX981_00533	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FX981_00536	COG4980	gas vesicle protein
FX981_00537	COG1846	Transcriptional regulator
FX981_00541	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FX981_00544	COG3481	metal-dependent phosphohydrolase, HD sub domain
FX981_00545	COG4717	serine-type aminopeptidase activity
FX981_00546	COG0420	3'-5' exonuclease activity
FX981_00548	COG1024	Enoyl-CoA hydratase
FX981_00550	COG0490	domain, Protein
FX981_00551	COG0475	glutathione-regulated potassium exporter activity
FX981_00553	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FX981_00554	COG0561	phosphatase activity
FX981_00555	COG3679	Belongs to the UPF0342 family
FX981_00556	COG4399	Belongs to the UPF0754 family
FX981_00557	COG0189	ligase activity
FX981_00558	COG0189	ligase activity
FX981_00560	COG2508	Transcriptional regulator
FX981_00561	COG3842	ATPase activity
FX981_00564	COG0702	epimerase
FX981_00565	COG1132	(ABC) transporter
FX981_00566	COG1132	(ABC) transporter
FX981_00567	COG0589	response to stress
FX981_00568	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FX981_00569	COG0726	polysaccharide deacetylase
FX981_00570	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FX981_00571	COG0668	transmembrane transport
FX981_00572	COG0584	glycerophosphoryl diester phosphodiesterase
FX981_00573	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FX981_00574	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FX981_00576	COG1253	flavin adenine dinucleotide binding
FX981_00577	COG0789	Transcriptional regulator
FX981_00578	COG1253	flavin adenine dinucleotide binding
FX981_00579	COG0204	Acyl-transferase
FX981_00580	COG1595	DNA-templated transcription, initiation
FX981_00583	COG0531	amino acid
FX981_00584	COG1388	LysM domain
FX981_00584	COG0791	NLP P60 protein
FX981_00585	COG1785	Belongs to the alkaline phosphatase family
FX981_00586	COG2719	SpoVR family
FX981_00587	COG1017	nitric oxide dioxygenase activity
FX981_00587	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FX981_00588	COG1959	2 iron, 2 sulfur cluster binding
FX981_00589	COG0753	catalase activity
FX981_00592	COG2197	response regulator
FX981_00593	COG4585	Histidine kinase
FX981_00593	COG2203	Gaf domain
FX981_00594	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FX981_00595	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FX981_00596	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FX981_00597	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FX981_00598	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FX981_00599	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FX981_00600	COG3835	regulator
FX981_00603	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FX981_00603	COG3153	acetyltransferase
FX981_00604	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FX981_00606	COG0564	pseudouridine synthase activity
FX981_00607	COG3764	Sortase (surface protein transpeptidase)
FX981_00608	COG0737	Belongs to the 5'-nucleotidase family
FX981_00608	COG1525	nuclease
FX981_00608	COG4085	toxin activity
FX981_00609	COG5002	protein histidine kinase activity
FX981_00610	COG5577	PFAM Coat F domain
FX981_00615	COG3706	GGDEF domain
FX981_00616	COG1278	Cold shock
FX981_00619	COG0655	NAD(P)H dehydrogenase (quinone) activity
FX981_00620	COG2814	Major facilitator Superfamily
FX981_00621	COG1566	PFAM secretion protein HlyD family protein
FX981_00622	COG2718	Belongs to the UPF0229 family
FX981_00623	COG2766	serine protein kinase
FX981_00624	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FX981_00626	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FX981_00627	COG3382	B3 4 domain protein
FX981_00633	COG1131	(ABC) transporter
FX981_00636	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FX981_00637	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FX981_00638	COG1116	anion transmembrane transporter activity
FX981_00641	COG0681	Belongs to the peptidase S26 family
FX981_00642	COG1368	sulfuric ester hydrolase activity
FX981_00673	COG0735	belongs to the Fur family
FX981_00674	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FX981_00675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FX981_00676	COG4129	membrane
FX981_00679	COG0747	negative chemotaxis
FX981_00680	COG4608	Belongs to the ABC transporter superfamily
FX981_00681	COG0444	Belongs to the ABC transporter superfamily
FX981_00682	COG1132	(ABC) transporter
FX981_00683	COG3557	Belongs to the UPF0374 family
FX981_00686	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_00688	COG1194	a g-specific adenine glycosylase
FX981_00689	COG1988	membrane-bound metal-dependent
FX981_00699	COG1191	sigma factor activity
FX981_00701	COG2140	Oxalate decarboxylase
FX981_00703	COG4485	Bacterial membrane protein, YfhO
FX981_00704	COG0463	Glycosyl transferase, family 2
FX981_00709	COG2137	regulation of response to DNA damage stimulus
FX981_00710	COG1090	epimerase
FX981_00713	COG0778	Nitroreductase
FX981_00717	COG0392	lysyltransferase activity
FX981_00717	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FX981_00718	COG1846	Transcriptional regulator
FX981_00720	COG2318	DinB family
FX981_00724	COG1595	DNA-templated transcription, initiation
FX981_00725	COG1742	UPF0060 membrane protein
FX981_00726	COG0492	ferredoxin-NADP+ reductase activity
FX981_00727	COG2755	lipolytic protein G-D-S-L family
FX981_00728	COG4637	Psort location Cytoplasmic, score
FX981_00730	COG1309	transcriptional regulator
FX981_00731	COG2076	Multidrug Resistance protein
FX981_00732	COG2076	Multidrug Resistance protein
FX981_00741	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FX981_00743	COG2814	Major facilitator Superfamily
FX981_00744	COG0789	Transcriptional regulator
FX981_00745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FX981_00746	COG1942	4-Oxalocrotonate Tautomerase
FX981_00747	COG0583	DNA-binding transcription factor activity
FX981_00750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FX981_00751	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FX981_00753	COG0598	Magnesium transport protein CorA
FX981_00755	COG0726	polysaccharide deacetylase
FX981_00757	COG0535	radical SAM domain protein
FX981_00758	COG0668	transmembrane transport
FX981_00760	COG0217	transcriptional regulatory protein
FX981_00761	COG1715	Restriction endonuclease
FX981_00763	COG0387	Pfam Sodium calcium exchanger
FX981_00765	COG0477	Major facilitator Superfamily
FX981_00766	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FX981_00768	COG1295	ribonuclease BN
FX981_00769	COG4980	gas vesicle protein
FX981_00770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FX981_00771	COG1115	amino acid carrier protein
FX981_00772	COG4840	Belongs to the UPF0435 family
FX981_00773	COG0693	protein deglycase activity
FX981_00774	COG0737	Belongs to the 5'-nucleotidase family
FX981_00776	COG2188	Transcriptional regulator
FX981_00777	COG0366	Alpha amylase catalytic
FX981_00778	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_00778	COG1263	PTS System
FX981_00780	COG0840	transmembrane signaling receptor activity
FX981_00781	COG0076	glutamate decarboxylase activity
FX981_00782	COG1368	sulfuric ester hydrolase activity
FX981_00785	COG3739	integral membrane protein
FX981_00786	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_00786	COG1263	PTS System
FX981_00787	COG0024	Methionine aminopeptidase
FX981_00790	COG2258	MOSC domain
FX981_00791	COG1254	Belongs to the acylphosphatase family
FX981_00792	COG0583	DNA-binding transcription factor activity
FX981_00793	COG0477	Major facilitator Superfamily
FX981_00794	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FX981_00795	COG1695	Transcriptional regulator
FX981_00796	COG3479	Phenolic acid decarboxylase
FX981_00798	COG2851	Citrate transporter
FX981_00799	COG3181	Tripartite tricarboxylate transporter family receptor
FX981_00800	COG4565	transcriptional regulatory protein
FX981_00801	COG3290	protein histidine kinase activity
FX981_00803	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FX981_00803	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FX981_00805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FX981_00806	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FX981_00806	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FX981_00810	COG2130	NADP-dependent
FX981_00813	COG0513	Belongs to the DEAD box helicase family
FX981_00814	COG0488	(ABC) transporter
FX981_00815	COG2814	Major facilitator Superfamily
FX981_00816	COG0789	Transcriptional regulator
FX981_00817	COG1469	GTP cyclohydrolase I activity
FX981_00818	COG0488	(ABC) transporter
FX981_00819	COG0463	Glycosyl transferase, family 2
FX981_00820	COG0531	amino acid
FX981_00823	COG0071	Belongs to the small heat shock protein (HSP20) family
FX981_00826	COG0471	metal ion transport
FX981_00828	COG2223	nitrite transmembrane transporter activity
FX981_00829	COG1442	glycosyl transferase family 8
FX981_00830	COG1216	Glycosyl transferase, family 2
FX981_00831	COG1442	glycosyl transferase family 8
FX981_00832	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FX981_00833	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FX981_00838	COG2211	Major facilitator Superfamily
FX981_00840	COG1486	melibiose metabolic process
FX981_00843	COG0492	ferredoxin-NADP+ reductase activity
FX981_00844	COG1959	2 iron, 2 sulfur cluster binding
FX981_00846	COG1486	melibiose metabolic process
FX981_00847	COG1263	PTS System
FX981_00847	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_00848	COG1737	Transcriptional regulator
FX981_00850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FX981_00852	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FX981_00853	COG1597	lipid kinase activity
FX981_00854	COG1957	nucleoside hydrolase
FX981_00855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FX981_00856	COG1309	transcriptional regulator
FX981_00857	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FX981_00858	COG0154	amidase activity
FX981_00859	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FX981_00860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FX981_00861	COG1285	pathogenesis
FX981_00862	COG1785	Belongs to the alkaline phosphatase family
FX981_00863	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FX981_00869	COG1960	acyl-CoA dehydrogenase activity
FX981_00872	COG1250	3-hydroxyacyl-CoA dehydrogenase
FX981_00875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FX981_00878	COG4851	CamS sex pheromone cAM373 precursor
FX981_00879	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FX981_00880	COG0210	DNA helicase
FX981_00881	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FX981_00884	COG0069	glutamate synthase activity
FX981_00885	COG4496	protein, YerC YecD
FX981_00886	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FX981_00888	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FX981_00889	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FX981_00890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FX981_00891	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FX981_00895	COG0151	Belongs to the GarS family
FX981_00896	COG0138	bifunctional purine biosynthesis protein purh
FX981_00897	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FX981_00898	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FX981_00899	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FX981_00900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FX981_00901	COG0047	phosphoribosylformylglycinamidine synthase activity
FX981_00902	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FX981_00903	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FX981_00904	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FX981_00905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FX981_00906	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FX981_00908	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FX981_00909	COG3064	Membrane
FX981_00912	COG2252	PERMEase
FX981_00913	COG0583	DNA-binding transcription factor activity
FX981_00914	COG2814	Major facilitator Superfamily
FX981_00916	COG1595	DNA-templated transcription, initiation
FX981_00920	COG1404	Belongs to the peptidase S8 family
FX981_00924	COG2207	Transcriptional regulator
FX981_00926	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FX981_00928	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FX981_00929	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FX981_00929	COG0519	Catalyzes the synthesis of GMP from XMP
FX981_00930	COG1305	Transglutaminase-like
FX981_00931	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FX981_00932	COG0714	Associated with various cellular activities
FX981_00933	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FX981_00934	COG1113	amino acid transport
FX981_00935	COG2132	Multicopper oxidase
FX981_00937	COG0823	Involved in the tonB-independent uptake of proteins
FX981_00938	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FX981_00944	COG2808	Putative FMN-binding domain
FX981_00945	COG0456	acetyltransferase
FX981_00946	COG1846	Transcriptional regulator
FX981_00948	COG0459	protein refolding
FX981_00949	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FX981_00950	COG1266	CAAX protease self-immunity
FX981_00953	COG2801	Transposase and inactivated derivatives
FX981_00955	COG0805	protein transport
FX981_00956	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FX981_00957	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FX981_00958	COG0315	cyclic pyranopterin monophosphate synthase activity
FX981_00959	COG0488	(ABC) transporter
FX981_00960	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FX981_00961	COG0456	acetyltransferase
FX981_00962	COG1214	PFAM Peptidase M22, glycoprotease
FX981_00963	COG0802	atpase or kinase
FX981_00964	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FX981_00972	COG1301	dicarboxylic acid transport
FX981_00974	COG0697	spore germination
FX981_00975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FX981_00981	COG1396	sequence-specific DNA binding
FX981_00984	COG0778	Nitroreductase
FX981_00985	COG1846	Transcriptional regulator
FX981_00986	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FX981_00987	COG1309	transcriptional regulator
FX981_00993	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FX981_00994	COG2814	Major facilitator Superfamily
FX981_00998	COG0252	asparaginase activity
FX981_01000	COG4221	oxidoreductase activity
FX981_01002	COG0477	Major facilitator Superfamily
FX981_01007	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FX981_01009	COG0789	Transcriptional regulator
FX981_01010	COG1064	alcohol dehydrogenase
FX981_01012	COG1404	Belongs to the peptidase S8 family
FX981_01013	COG1278	Cold shock
FX981_01014	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FX981_01014	COG0456	acetyltransferase
FX981_01015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FX981_01016	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FX981_01024	COG3284	Transcriptional regulator
FX981_01025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FX981_01026	COG0508	dehydrogenase complex catalyzes the overall conversion of
FX981_01027	COG0022	dehydrogenase e1 component
FX981_01028	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FX981_01029	COG3091	SprT-like family
FX981_01030	COG2183	response to ionizing radiation
FX981_01031	COG2208	phosphoserine phosphatase activity
FX981_01032	COG1191	sigma factor activity
FX981_01033	COG2172	sigma factor antagonist activity
FX981_01034	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_01035	COG2208	phosphoserine phosphatase activity
FX981_01036	COG2172	sigma factor antagonist activity
FX981_01037	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_01038	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_01039	COG2337	Toxic component of a toxin-antitoxin (TA) module
FX981_01040	COG0864	Transcriptional regulator
FX981_01041	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FX981_01042	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FX981_01043	COG0736	holo-[acyl-carrier-protein] synthase activity
FX981_01044	COG0705	Rhomboid family
FX981_01045	COG3428	Bacterial PH domain
FX981_01046	COG3402	PFAM membrane-flanked domain
FX981_01047	COG0513	Belongs to the DEAD box helicase family
FX981_01050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FX981_01051	COG1181	Belongs to the D-alanine--D-alanine ligase family
FX981_01052	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_01055	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FX981_01056	COG1131	(ABC) transporter
FX981_01057	COG1301	dicarboxylic acid transport
FX981_01058	COG0628	permease
FX981_01059	COG1301	dicarboxylic acid transport
FX981_01060	COG4565	transcriptional regulatory protein
FX981_01061	COG3290	protein histidine kinase activity
FX981_01062	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FX981_01063	COG2217	Heavy metal translocating P-type atpase
FX981_01064	COG2261	transglycosylase associated protein
FX981_01065	COG1914	H( )-stimulated, divalent metal cation uptake system
FX981_01066	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FX981_01071	COG5444	nuclease activity
FX981_01072	COG0028	Belongs to the TPP enzyme family
FX981_01073	COG0531	amino acid
FX981_01075	COG1215	transferase activity, transferring glycosyl groups
FX981_01076	COG5298	Protein conserved in bacteria
FX981_01077	COG3706	GGDEF domain
FX981_01078	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FX981_01079	COG0551	DNA topoisomerase type I activity
FX981_01079	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FX981_01080	COG0473	3-isopropylmalate dehydrogenase activity
FX981_01081	COG0697	spore germination
FX981_01082	COG2207	Transcriptional regulator
FX981_01082	COG1917	Cupin 2, conserved barrel domain protein
FX981_01083	COG1802	Transcriptional regulator
FX981_01084	COG2814	Major facilitator Superfamily
FX981_01089	COG3871	stress protein (general stress protein 26)
FX981_01091	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_01092	COG2226	methyltransferase
FX981_01093	COG3711	transcriptional antiterminator
FX981_01095	COG2755	lipolytic protein G-D-S-L family
FX981_01096	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FX981_01097	COG1414	Transcriptional regulator
FX981_01098	COG1984	allophanate hydrolase subunit 2
FX981_01099	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FX981_01100	COG4336	lyase activity
FX981_01101	COG1914	H( )-stimulated, divalent metal cation uptake system
FX981_01102	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FX981_01103	COG0561	phosphatase activity
FX981_01105	COG0346	lactoylglutathione lyase activity
FX981_01108	COG0789	Transcriptional regulator
FX981_01109	COG0300	oxidoreductase activity
FX981_01110	COG0840	transmembrane signaling receptor activity
FX981_01111	COG0246	Mannitol dehydrogenase
FX981_01112	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_01113	COG2213	PTS system mannitol-specific
FX981_01114	COG2372	response to copper ion
FX981_01114	COG1276	copper resistance
FX981_01115	COG4549	nuclear export factor GLE1
FX981_01116	COG2249	NAD(P)H dehydrogenase (quinone) activity
FX981_01117	COG1012	belongs to the aldehyde dehydrogenase family
FX981_01118	COG0531	amino acid
FX981_01119	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FX981_01120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FX981_01121	COG0640	Transcriptional regulator
FX981_01123	COG1309	transcriptional regulator
FX981_01124	COG2814	Major facilitator Superfamily
FX981_01125	COG0527	aspartate kinase activity
FX981_01126	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_01127	COG3850	Histidine kinase
FX981_01127	COG5002	protein histidine kinase activity
FX981_01128	COG0745	RESPONSE REGULATOR receiver
FX981_01129	COG2079	MmgE PrpD family protein
FX981_01131	COG1126	abc transporter atp-binding protein
FX981_01132	COG0765	amino acid transport
FX981_01133	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_01136	COG5434	Belongs to the glycosyl hydrolase 28 family
FX981_01137	COG3104	oligopeptide transport
FX981_01138	COG1904	glucuronate isomerase
FX981_01140	COG0673	inositol 2-dehydrogenase activity
FX981_01141	COG1802	Transcriptional regulator
FX981_01142	COG1312	Catalyzes the dehydration of D-mannonate
FX981_01143	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_01145	COG0833	amino acid
FX981_01146	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_01147	COG0765	amino acid transport
FX981_01148	COG1126	abc transporter atp-binding protein
FX981_01149	COG2364	Membrane
FX981_01152	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FX981_01153	COG0697	spore germination
FX981_01154	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FX981_01157	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FX981_01158	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FX981_01159	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FX981_01161	COG1176	ABC-type spermidine putrescine transport system, permease component I
FX981_01162	COG3842	ATPase activity
FX981_01166	COG3209	COG3209 Rhs family protein
FX981_01167	COG3290	protein histidine kinase activity
FX981_01167	COG0840	transmembrane signaling receptor activity
FX981_01169	COG2746	aminoglycoside 3-N-acetyltransferase activity
FX981_01170	COG1522	sequence-specific DNA binding
FX981_01171	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FX981_01173	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_01174	COG0765	amino acid transport
FX981_01175	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FX981_01176	COG2508	Transcriptional regulator
FX981_01177	COG1012	belongs to the aldehyde dehydrogenase family
FX981_01178	COG0506	proline dehydrogenase activity
FX981_01179	COG3541	Predicted nucleotidyltransferase
FX981_01181	COG3458	cephalosporin-C deacetylase activity
FX981_01182	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FX981_01183	COG0583	DNA-binding transcription factor activity
FX981_01184	COG2226	methyltransferase
FX981_01185	COG0477	Major facilitator Superfamily
FX981_01186	COG1609	Transcriptional regulator
FX981_01187	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FX981_01188	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FX981_01189	COG1414	Transcriptional regulator
FX981_01191	COG2271	Major facilitator Superfamily
FX981_01192	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FX981_01194	COG0028	Belongs to the TPP enzyme family
FX981_01195	COG0710	3-dehydroquinate dehydratase activity
FX981_01196	COG1012	belongs to the aldehyde dehydrogenase family
FX981_01198	COG0457	Tetratricopeptide repeat
FX981_01201	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FX981_01202	COG3665	Urea carboxylase-associated protein
FX981_01203	COG1113	amino acid transport
FX981_01204	COG3403	YqcI/YcgG family
FX981_01206	COG1280	lysine exporter protein (LysE YggA)
FX981_01207	COG0738	Major facilitator superfamily
FX981_01208	COG0673	inositol 2-dehydrogenase activity
FX981_01209	COG0561	phosphatase activity
FX981_01210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FX981_01211	COG1609	Transcriptional regulator
FX981_01212	COG1620	l-lactate permease
FX981_01213	COG0039	L-malate dehydrogenase activity
FX981_01214	COG1288	antiporter activity
FX981_01215	COG1473	amidohydrolase
FX981_01218	COG2113	Glycine betaine
FX981_01219	COG4176	ABC-type proline glycine betaine transport system permease component
FX981_01220	COG4175	Glycine betaine
FX981_01220	COG0517	IMP dehydrogenase activity
FX981_01221	COG3853	Toxic anion resistance protein (TelA)
FX981_01227	COG0861	Integral membrane protein TerC family
FX981_01228	COG2310	stress, protein
FX981_01229	COG2310	stress, protein
FX981_01230	COG2310	stress, protein
FX981_01231	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FX981_01233	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_01234	COG3773	Cell wall hydrolase
FX981_01237	COG1668	transmembrane transport
FX981_01238	COG4555	ABC transporter
FX981_01239	COG3279	Response regulator of the LytR AlgR family
FX981_01240	COG3290	protein histidine kinase activity
FX981_01241	COG0667	Aldo Keto reductase
FX981_01243	COG4585	Histidine kinase
FX981_01244	COG2197	response regulator
FX981_01246	COG3012	SEC-C Motif Domain Protein
FX981_01246	COG1405	negative regulation of cell septum assembly
FX981_01247	COG0784	Response regulator, receiver
FX981_01248	COG4191	Histidine kinase
FX981_01249	COG2066	Belongs to the glutaminase family
FX981_01250	COG1115	amino acid carrier protein
FX981_01251	COG0596	Alpha beta hydrolase
FX981_01253	COG0531	amino acid
FX981_01254	COG0318	PFAM AMP-dependent synthetase and ligase
FX981_01255	COG1846	Transcriptional regulator
FX981_01256	COG1063	alcohol dehydrogenase
FX981_01257	COG1917	Cupin 2, conserved barrel domain protein
FX981_01258	COG1309	transcriptional regulator
FX981_01260	COG1404	Belongs to the peptidase S8 family
FX981_01264	COG2814	Major facilitator Superfamily
FX981_01267	COG1695	Transcriptional regulator
FX981_01268	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FX981_01269	COG2040	homocysteine
FX981_01270	COG0833	amino acid
FX981_01273	COG1404	Belongs to the peptidase S8 family
FX981_01274	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_01274	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_01275	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_01276	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_01277	COG0383	alpha-mannosidase activity
FX981_01278	COG1940	carbohydrate kinase activity
FX981_01279	COG3711	transcriptional antiterminator
FX981_01279	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_01283	COG2723	6-phospho-beta-galactosidase activity
FX981_01284	COG2190	(PTS) system
FX981_01284	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_01284	COG1263	PTS System
FX981_01285	COG3711	transcriptional antiterminator
FX981_01286	COG0531	amino acid
FX981_01288	COG0371	Dehydrogenase
FX981_01289	COG0656	L-ascorbic acid biosynthetic process
FX981_01291	COG1683	Conserved Protein
FX981_01293	COG1846	Transcriptional regulator
FX981_01295	COG2814	Major facilitator Superfamily
FX981_01296	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FX981_01298	COG0730	response to heat
FX981_01299	COG0425	Belongs to the sulfur carrier protein TusA family
FX981_01300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FX981_01300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FX981_01301	COG0425	Belongs to the sulfur carrier protein TusA family
FX981_01301	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FX981_01303	COG2210	Belongs to the sulfur carrier protein TusA family
FX981_01304	COG1937	Protein conserved in bacteria
FX981_01308	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FX981_01309	COG1331	Highly conserved protein containing a thioredoxin domain
FX981_01311	COG2271	Major facilitator Superfamily
FX981_01312	COG0584	glycerophosphoryl diester phosphodiesterase
FX981_01314	COG2801	Transposase and inactivated derivatives
FX981_01315	COG1113	amino acid transport
FX981_01319	COG2311	Membrane
FX981_01321	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_01322	COG1413	lyase activity
FX981_01324	COG1131	(ABC) transporter
FX981_01327	COG1131	(ABC) transporter
FX981_01330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FX981_01331	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FX981_01332	COG4856	YbbR-like protein
FX981_01333	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FX981_01334	COG5662	AntiSigma factor
FX981_01335	COG1595	DNA-templated transcription, initiation
FX981_01342	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FX981_01343	COG1737	Transcriptional regulator
FX981_01344	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_01344	COG1263	PTS System
FX981_01345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FX981_01346	COG1472	Belongs to the glycosyl hydrolase 3 family
FX981_01347	COG3876	Protein conserved in bacteria
FX981_01348	COG0385	Bile acid
FX981_01349	COG0659	secondary active sulfate transmembrane transporter activity
FX981_01355	COG0726	polysaccharide deacetylase
FX981_01356	COG2194	sulfuric ester hydrolase activity
FX981_01358	COG0489	protein tyrosine kinase activity
FX981_01359	COG0860	N-Acetylmuramoyl-L-alanine amidase
FX981_01364	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FX981_01365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FX981_01366	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FX981_01367	COG0101	tRNA pseudouridine synthase activity
FX981_01368	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FX981_01369	COG1122	ATPase activity
FX981_01370	COG1122	ATPase activity
FX981_01371	COG0203	ribosomal protein L17
FX981_01372	COG0202	RNA polymerase activity
FX981_01373	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FX981_01374	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FX981_01375	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FX981_01376	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FX981_01377	COG0024	Methionine aminopeptidase
FX981_01378	COG0563	adenylate kinase activity
FX981_01379	COG0201	protein transport
FX981_01380	COG0200	Binds to the 23S rRNA
FX981_01381	COG1841	ribosomal large subunit assembly
FX981_01382	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FX981_01383	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FX981_01384	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FX981_01385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FX981_01386	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FX981_01387	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FX981_01388	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FX981_01389	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FX981_01390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FX981_01391	COG0255	Belongs to the universal ribosomal protein uL29 family
FX981_01392	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FX981_01393	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FX981_01394	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FX981_01395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FX981_01396	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FX981_01397	COG0089	rRNA binding
FX981_01398	COG0088	Forms part of the polypeptide exit tunnel
FX981_01399	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FX981_01400	COG0051	transcription antitermination factor activity, RNA binding
FX981_01401	COG0596	Alpha beta hydrolase
FX981_01402	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FX981_01403	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FX981_01404	COG0049	tRNA binding
FX981_01405	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FX981_01406	COG1358	cellular component organization or biogenesis
FX981_01407	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FX981_01408	COG0085	RNA polymerase activity
FX981_01409	COG2813	Specifically methylates the guanine in position
FX981_01410	COG0222	ribosome binding
FX981_01411	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FX981_01412	COG0081	regulation of translation
FX981_01413	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FX981_01414	COG0250	Participates in transcription elongation, termination and antitermination
FX981_01415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FX981_01416	COG1595	DNA-templated transcription, initiation
FX981_01417	COG3688	RNA-binding protein containing a PIN domain
FX981_01418	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FX981_01419	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FX981_01420	COG0215	cysteine-tRNA ligase activity
FX981_01421	COG1045	serine acetyltransferase
FX981_01422	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FX981_01423	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FX981_01424	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FX981_01425	COG4956	integral membrane protein (PIN domain superfamily)
FX981_01426	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FX981_01427	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FX981_01428	COG0542	response to heat
FX981_01429	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FX981_01430	COG3880	PFAM UvrB UvrC protein
FX981_01431	COG4463	regulation of RNA biosynthetic process
FX981_01447	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FX981_01448	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FX981_01449	COG1396	sequence-specific DNA binding
FX981_01450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FX981_01451	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FX981_01452	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FX981_01453	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FX981_01454	COG0512	Glutamine amidotransferase of anthranilate synthase
FX981_01455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FX981_01456	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FX981_01457	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FX981_01458	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FX981_01459	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FX981_01460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FX981_01462	COG0037	tRNA processing
FX981_01463	COG0515	serine threonine protein kinase
FX981_01464	COG2304	oxidoreductase activity
FX981_01465	COG2208	phosphoserine phosphatase activity
FX981_01468	COG1098	S1 RNA binding domain
FX981_01469	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FX981_01472	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FX981_01473	COG3956	TIGRFAM MazG family protein
FX981_01474	COG2244	polysaccharide biosynthetic process
FX981_01475	COG2002	toxin-antitoxin pair type II binding
FX981_01476	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FX981_01478	COG0193	aminoacyl-tRNA hydrolase activity
FX981_01479	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FX981_01480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FX981_01482	COG2088	sporulation resulting in formation of a cellular spore
FX981_01483	COG0251	oxidation-reduction process
FX981_01484	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FX981_01485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FX981_01487	COG4466	Protein conserved in bacteria
FX981_01489	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FX981_01490	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FX981_01491	COG3583	domain protein
FX981_01491	COG3584	3D domain protein
FX981_01492	COG0084	hydrolase, TatD family'
FX981_01493	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FX981_01493	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FX981_01494	COG2002	toxin-antitoxin pair type II binding
FX981_01495	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FX981_01496	COG2827	Endonuclease containing a URI domain
FX981_01497	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FX981_01498	COG4467	Involved in initiation control of chromosome replication
FX981_01499	COG1774	PSP1 C-terminal conserved region
FX981_01500	COG0470	DNA polymerase III
FX981_01501	COG1728	Protein conserved in bacteria
FX981_01502	COG3870	Protein conserved in bacteria
FX981_01503	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FX981_01504	COG1982	Orn Lys Arg decarboxylase major
FX981_01505	COG3853	Toxic anion resistance protein (TelA)
FX981_01506	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FX981_01515	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FX981_01516	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FX981_01517	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FX981_01518	COG0590	tRNA wobble adenosine to inosine editing
FX981_01519	COG1335	isochorismatase
FX981_01520	COG3858	chitin binding
FX981_01520	COG1388	LysM domain
FX981_01521	COG1428	Deoxynucleoside kinase
FX981_01522	COG1428	Deoxynucleoside kinase
FX981_01524	COG0840	transmembrane signaling receptor activity
FX981_01525	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FX981_01526	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FX981_01527	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FX981_01528	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FX981_01529	COG1686	Belongs to the peptidase S11 family
FX981_01530	COG0517	IMP dehydrogenase activity
FX981_01530	COG0516	GMP reductase activity
FX981_01537	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FX981_01538	COG0187	DNA topoisomerase II activity
FX981_01540	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FX981_01541	COG2501	S4 domain
FX981_01542	COG0592	DNA-directed DNA polymerase activity
FX981_01543	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FX981_01544	COG0594	ribonuclease P activity
FX981_01545	COG0706	membrane insertase activity
FX981_01546	COG1847	R3H domain protein
FX981_01547	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FX981_01548	COG0445	tRNA wobble uridine modification
FX981_01549	COG0357	Ribosomal RNA small subunit methyltransferase G
FX981_01550	COG1475	DNA binding
FX981_01551	COG1192	Involved in chromosome partitioning
FX981_01552	COG1475	DNA binding
FX981_01554	COG3949	Membrane
FX981_01557	COG4481	Protein conserved in bacteria
FX981_01558	COG0012	GTP binding
FX981_01559	COG0360	Binds together with S18 to 16S ribosomal RNA
FX981_01560	COG0629	single-stranded DNA binding
FX981_01561	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FX981_01562	COG0517	IMP dehydrogenase activity
FX981_01562	COG1125	glycine betaine transport
FX981_01563	COG1174	glycine betaine transport
FX981_01564	COG0346	lactoylglutathione lyase activity
FX981_01565	COG0400	carboxylic ester hydrolase activity
FX981_01566	COG0655	NAD(P)H dehydrogenase (quinone) activity
FX981_01567	COG0753	catalase activity
FX981_01569	COG1595	DNA-templated transcription, initiation
FX981_01571	COG1227	inorganic diphosphatase activity
FX981_01572	COG4241	membrane
FX981_01573	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FX981_01574	COG0359	binds to the 23S rRNA
FX981_01575	COG2807	transmembrane transport
FX981_01576	COG3093	addiction module antidote protein HigA
FX981_01577	COG2819	hydrolase of the alpha beta superfamily
FX981_01578	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FX981_01579	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FX981_01579	COG2207	Transcriptional regulator
FX981_01580	COG3251	PFAM MbtH domain protein
FX981_01581	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FX981_01582	COG3433	isochorismatase activity
FX981_01582	COG1535	isochorismatase
FX981_01583	COG1021	2,3-dihydroxybenzoate-AMP ligase
FX981_01584	COG1169	isochorismate synthase
FX981_01585	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_01586	COG2819	hydrolase of the alpha beta superfamily
FX981_01590	COG0305	Participates in initiation and elongation during chromosome replication
FX981_01591	COG0346	lactoylglutathione lyase activity
FX981_01592	COG2124	cytochrome p450
FX981_01594	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FX981_01595	COG2311	Membrane
FX981_01597	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FX981_01602	COG0745	RESPONSE REGULATOR receiver
FX981_01603	COG5002	protein histidine kinase activity
FX981_01604	COG4863	YycH protein
FX981_01605	COG4853	Protein conserved in bacteria
FX981_01606	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FX981_01607	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FX981_01608	COG0456	acetyltransferase
FX981_01612	COG4720	Psort location CytoplasmicMembrane, score
FX981_01614	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FX981_01616	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FX981_01624	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FX981_01627	COG4786	Flagellar basal body rod
FX981_01628	COG5444	nuclease activity
FX981_01632	COG0640	Transcriptional regulator
FX981_01633	COG2814	Major facilitator Superfamily
FX981_01635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FX981_01639	COG0583	DNA-binding transcription factor activity
FX981_01640	COG0384	phenazine biosynthesis protein PhzF
FX981_01642	COG2188	Transcriptional regulator
FX981_01644	COG2723	6-phospho-beta-galactosidase activity
FX981_01646	COG5444	nuclease activity
FX981_01648	COG2814	Major facilitator Superfamily
FX981_01649	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FX981_01650	COG2814	Major facilitator Superfamily
FX981_01653	COG1113	amino acid transport
FX981_01660	COG0457	Tetratricopeptide repeat
FX981_01662	COG0577	efflux transmembrane transporter activity
FX981_01662	COG1136	(ABC) transporter
FX981_01664	COG2814	Major facilitator Superfamily
FX981_01665	COG1309	transcriptional regulator
FX981_01666	COG3835	regulator
FX981_01667	COG2610	gluconate transmembrane transporter activity
FX981_01668	COG1929	Belongs to the glycerate kinase type-1 family
FX981_01669	COG2824	Alkylphosphonate utilization operon protein PhnA
FX981_01670	COG1131	(ABC) transporter
FX981_01671	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FX981_01673	COG2851	Citrate transporter
FX981_01674	COG1874	Beta-galactosidase
FX981_01676	COG3833	ABC-type maltose transport systems, permease component
FX981_01677	COG1175	transmembrane transport
FX981_01678	COG2182	Extracellular solute-binding protein
FX981_01679	COG1609	Transcriptional regulator
FX981_01680	COG0583	DNA-binding transcription factor activity
FX981_01684	COG1737	Transcriptional regulator
FX981_01685	COG1070	Carbohydrate kinase
FX981_01687	COG4335	DNA alkylation repair
FX981_01688	COG1113	amino acid transport
FX981_01689	COG0840	transmembrane signaling receptor activity
FX981_01690	COG0673	inositol 2-dehydrogenase activity
FX981_01691	COG0789	Transcriptional regulator
FX981_01692	COG0561	phosphatase activity
FX981_01696	COG2755	lipolytic protein G-D-S-L family
FX981_01696	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FX981_01698	COG2390	Transcriptional regulator
FX981_01699	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FX981_01700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FX981_01701	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FX981_01702	COG1846	Transcriptional regulator
FX981_01703	COG0778	Nitroreductase
FX981_01704	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FX981_01705	COG4412	M6 family metalloprotease domain protein
FX981_01705	COG3291	Pkd domain containing protein
FX981_01711	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FX981_01712	COG4721	ABC-type cobalt transport system, permease component
FX981_01713	COG1122	ATPase activity
FX981_01714	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FX981_01716	COG3878	Protein conserved in bacteria
FX981_01717	COG3711	transcriptional antiterminator
FX981_01718	COG1263	PTS System
FX981_01718	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_01718	COG2190	(PTS) system
FX981_01719	COG2723	6-phospho-beta-galactosidase activity
FX981_01721	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FX981_01722	COG2610	gluconate transmembrane transporter activity
FX981_01724	COG2084	Dehydrogenase
FX981_01725	COG1737	Transcriptional regulator
FX981_01728	COG2195	Cleaves the N-terminal amino acid of tripeptides
FX981_01729	COG4842	Belongs to the WXG100 family
FX981_01734	COG1396	sequence-specific DNA binding
FX981_01735	COG0252	asparaginase activity
FX981_01736	COG1027	Aspartate ammonia-lyase
FX981_01737	COG1757	Na H antiporter
FX981_01742	COG3711	transcriptional antiterminator
FX981_01742	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_01743	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FX981_01744	COG2723	6-phospho-beta-galactosidase activity
FX981_01745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FX981_01746	COG1447	Phosphotransferase system cellobiose-specific component IIA
FX981_01747	COG0726	polysaccharide deacetylase
FX981_01749	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FX981_01749	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FX981_01750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FX981_01750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FX981_01751	COG2514	catechol 2,3-dioxygenase activity
FX981_01752	COG1733	regulation of RNA biosynthetic process
FX981_01753	COG5386	Cell surface protein
FX981_01754	COG5386	Cell surface protein
FX981_01759	COG4509	Sortase family
FX981_01763	COG1271	oxidase subunit
FX981_01764	COG1294	oxidase, subunit
FX981_01765	COG4988	ABC transporter
FX981_01766	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FX981_01767	COG3866	Pectate lyase
FX981_01768	COG1595	DNA-templated transcription, initiation
FX981_01771	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FX981_01775	COG3711	transcriptional antiterminator
FX981_01775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_01776	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FX981_01777	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FX981_01778	COG1447	Phosphotransferase system cellobiose-specific component IIA
FX981_01779	COG1486	melibiose metabolic process
FX981_01782	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FX981_01783	COG3420	alginic acid biosynthetic process
FX981_01785	COG1129	ABC transporter
FX981_01786	COG1172	Belongs to the binding-protein-dependent transport system permease family
FX981_01787	COG2357	RelA SpoT domain protein
FX981_01789	COG0457	Tetratricopeptide repeat
FX981_01790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_01791	COG0765	amino acid transport
FX981_01793	COG0346	lactoylglutathione lyase activity
FX981_01794	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FX981_01795	COG1346	cytolysis
FX981_01796	COG1380	Effector of murein hydrolase LrgA
FX981_01797	COG0583	DNA-binding transcription factor activity
FX981_01798	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FX981_01799	COG0352	thiamine-phosphate diphosphorylase activity
FX981_01803	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FX981_01804	COG3162	membrane
FX981_01808	COG2246	polysaccharide biosynthetic process
FX981_01811	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FX981_01812	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FX981_01813	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FX981_01815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FX981_01816	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FX981_01817	COG1845	cytochrome c oxidase, subunit III
FX981_01818	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FX981_01820	COG0772	Belongs to the SEDS family
FX981_01821	COG0778	Nitroreductase
FX981_01822	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FX981_01823	COG1404	Belongs to the peptidase S8 family
FX981_01825	COG3711	transcriptional antiterminator
FX981_01826	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_01826	COG1263	PTS System
FX981_01827	COG1621	beta-fructofuranosidase activity
FX981_01829	COG3964	amidohydrolase
FX981_01833	COG0351	phosphomethylpyrimidine kinase
FX981_01835	COG1216	Glycosyl transferase, family 2
FX981_01836	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FX981_01837	COG1012	belongs to the aldehyde dehydrogenase family
FX981_01839	COG2233	PERMEase
FX981_01840	COG2363	Small membrane protein
FX981_01845	COG0463	Glycosyl transferase, family 2
FX981_01846	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FX981_01847	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FX981_01848	COG0456	acetyltransferase
FX981_01849	COG2089	acid synthase
FX981_01850	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FX981_01851	COG3980	spore coat polysaccharide biosynthesis protein
FX981_01852	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FX981_01853	COG1088	dTDP-glucose 4,6-dehydratase activity
FX981_01854	COG1091	dTDP-4-dehydrorhamnose reductase activity
FX981_01855	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FX981_01856	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_01857	COG0436	Aminotransferase
FX981_01858	COG0151	Belongs to the GarS family
FX981_01859	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_01861	COG0077	Prephenate dehydratase
FX981_01862	COG2814	Major facilitator Superfamily
FX981_01863	COG1522	sequence-specific DNA binding
FX981_01864	COG2814	Major facilitator Superfamily
FX981_01866	COG0280	phosphate acetyltransferase
FX981_01869	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FX981_01887	COG4844	belongs to the
FX981_01888	COG1078	dGTPase activity
FX981_01889	COG3465	dGTPase activity
FX981_01890	COG1126	abc transporter atp-binding protein
FX981_01891	COG0765	amino acid transport
FX981_01892	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_01893	COG0765	amino acid transport
FX981_01894	COG0454	-acetyltransferase
FX981_01895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FX981_01896	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FX981_01897	COG0431	NADPH-dependent FMN reductase
FX981_01898	COG0583	DNA-binding transcription factor activity
FX981_01899	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FX981_01901	COG1942	4-Oxalocrotonate Tautomerase
FX981_01902	COG1994	Peptidase M50
FX981_01904	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FX981_01905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FX981_01906	COG0010	Belongs to the arginase family
FX981_01908	COG4506	Protein conserved in bacteria
FX981_01909	COG0018	arginyl-trna synthetase
FX981_01910	COG1619	proteins homologs of microcin C7 resistance protein MccF
FX981_01911	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FX981_01912	COG1132	(ABC) transporter
FX981_01913	COG1619	proteins homologs of microcin C7 resistance protein MccF
FX981_01915	COG4294	response to UV
FX981_01916	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FX981_01917	COG0247	lactate metabolic process
FX981_01917	COG2181	nitrate reductase activity
FX981_01918	COG0183	Belongs to the thiolase family
FX981_01919	COG1250	3-hydroxyacyl-CoA dehydrogenase
FX981_01920	COG1960	acyl-CoA dehydrogenase activity
FX981_01921	COG1960	acyl-CoA dehydrogenase activity
FX981_01929	COG3343	RNA polymerase activity
FX981_01930	COG0504	CTP synthase activity
FX981_01931	COG4821	SIS domain
FX981_01932	COG2204	response regulator
FX981_01933	COG0191	fructose-bisphosphate aldolase activity
FX981_01934	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FX981_01935	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FX981_01936	COG1494	fructose-1,6-bisphosphatase
FX981_01937	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FX981_01938	COG0254	rRNA binding
FX981_01939	COG1435	thymidine kinase activity
FX981_01940	COG0281	malic enzyme
FX981_01941	COG0679	Auxin Efflux Carrier
FX981_01942	COG0789	Transcriptional regulator
FX981_01943	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FX981_01944	COG2890	protein-(glutamine-N5) methyltransferase activity
FX981_01947	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FX981_01948	COG0009	L-threonylcarbamoyladenylate synthase
FX981_01949	COG1971	Probably functions as a manganese efflux pump
FX981_01950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FX981_01951	COG0698	ribose 5-phosphate isomerase
FX981_01952	COG4475	Protein of unknown function (DUF436)
FX981_01953	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FX981_01954	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FX981_01956	COG0356	it plays a direct role in the translocation of protons across the membrane
FX981_01957	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FX981_01958	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FX981_01959	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FX981_01960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FX981_01961	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FX981_01962	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FX981_01963	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FX981_01965	COG4836	Membrane
FX981_01967	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FX981_01968	COG2385	sporulation resulting in formation of a cellular spore
FX981_01969	COG2304	oxidoreductase activity
FX981_01970	COG2304	oxidoreductase activity
FX981_01971	COG0243	molybdopterin cofactor binding
FX981_01973	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FX981_01974	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FX981_01975	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FX981_01976	COG0523	cobalamin synthesis protein
FX981_01985	COG1247	-acetyltransferase
FX981_01986	COG0739	heme binding
FX981_01987	COG0347	Belongs to the P(II) protein family
FX981_01988	COG0004	ammonium transporteR
FX981_01991	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_01992	COG0477	Major facilitator Superfamily
FX981_01993	COG0671	phosphoesterase, PA-phosphatase related
FX981_01994	COG2814	Major facilitator Superfamily
FX981_01995	COG1846	Transcriptional regulator
FX981_01996	COG1609	Transcriptional regulator
FX981_01997	COG1077	Cell shape determining protein MreB Mrl
FX981_01998	COG4786	Flagellar basal body rod
FX981_01999	COG4786	Flagellar basal body rod
FX981_02000	COG0457	Tetratricopeptide repeat
FX981_02001	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FX981_02002	COG1970	mechanosensitive ion channel activity
FX981_02005	COG0561	phosphatase activity
FX981_02006	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_02006	COG2202	Pas domain
FX981_02007	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FX981_02008	COG4715	Zinc finger, swim domain protein
FX981_02010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FX981_02011	COG2059	Chromate
FX981_02012	COG2059	Chromate
FX981_02013	COG1522	sequence-specific DNA binding
FX981_02014	COG3527	Alpha-acetolactate decarboxylase
FX981_02015	COG0028	Belongs to the TPP enzyme family
FX981_02016	COG0583	DNA-binding transcription factor activity
FX981_02017	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FX981_02018	COG1879	ABC-type sugar transport system periplasmic component
FX981_02019	COG1172	Belongs to the binding-protein-dependent transport system permease family
FX981_02020	COG1129	ABC transporter
FX981_02021	COG1869	D-ribose catabolic process
FX981_02022	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FX981_02023	COG1609	Transcriptional regulator
FX981_02026	COG0697	spore germination
FX981_02027	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FX981_02029	COG2843	Capsule synthesis protein
FX981_02031	COG0791	NLP P60 protein
FX981_02032	COG0561	phosphatase activity
FX981_02033	COG1316	TRANSCRIPTIONal
FX981_02034	COG2814	Major facilitator Superfamily
FX981_02035	COG1215	transferase activity, transferring glycosyl groups
FX981_02037	COG0814	amino acid
FX981_02038	COG0697	spore germination
FX981_02039	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_02040	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FX981_02041	COG1609	Transcriptional regulator
FX981_02042	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FX981_02043	COG0800	Aldolase
FX981_02044	COG0454	-acetyltransferase
FX981_02046	COG2972	Histidine kinase
FX981_02047	COG2201	protein-glutamate methylesterase activity
FX981_02048	COG1653	transport
FX981_02049	COG1175	transmembrane transport
FX981_02051	COG1482	cell wall glycoprotein biosynthetic process
FX981_02052	COG4193	domain, Protein
FX981_02053	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FX981_02054	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FX981_02055	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FX981_02057	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FX981_02059	COG1682	transport, permease protein
FX981_02060	COG1134	teichoic acid transport
FX981_02061	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FX981_02062	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FX981_02063	COG1316	TRANSCRIPTIONal
FX981_02065	COG2385	sporulation resulting in formation of a cellular spore
FX981_02065	COG2247	cell wall binding repeat
FX981_02066	COG2247	cell wall binding repeat
FX981_02066	COG0860	N-Acetylmuramoyl-L-alanine amidase
FX981_02067	COG2247	cell wall binding repeat
FX981_02067	COG0860	N-Acetylmuramoyl-L-alanine amidase
FX981_02070	COG2244	polysaccharide biosynthetic process
FX981_02071	COG0297	glycogen (starch) synthase activity
FX981_02071	COG0438	transferase activity, transferring glycosyl groups
FX981_02072	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FX981_02073	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FX981_02074	COG3307	-O-antigen
FX981_02075	COG3206	protein involved in exopolysaccharide biosynthesis
FX981_02076	COG1215	transferase activity, transferring glycosyl groups
FX981_02077	COG0438	transferase activity, transferring glycosyl groups
FX981_02078	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FX981_02079	COG1316	TRANSCRIPTIONal
FX981_02080	COG1739	Uncharacterized protein family UPF0029
FX981_02081	COG4585	Histidine kinase
FX981_02082	COG2197	response regulator
FX981_02083	COG1307	EDD domain protein, DegV family
FX981_02084	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FX981_02086	COG1040	competence protein
FX981_02089	COG3418	PFAM FlgN family protein
FX981_02090	COG1256	bacterial-type flagellum assembly
FX981_02090	COG4786	Flagellar basal body rod
FX981_02091	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FX981_02093	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FX981_02094	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FX981_02095	COG1334	flagellar protein FlaG
FX981_02096	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FX981_02097	COG1516	flagellar protein fliS
FX981_02100	COG0840	transmembrane signaling receptor activity
FX981_02101	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FX981_02102	COG0653	protein targeting
FX981_02103	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FX981_02106	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FX981_02107	COG2010	Cytochrome c
FX981_02108	COG2884	Cell division ATP-binding protein ftsE
FX981_02109	COG2177	Part of the ABC transporter FtsEX involved in
FX981_02110	COG3883	PFAM NLP P60 protein
FX981_02110	COG0791	NLP P60 protein
FX981_02111	COG0730	response to heat
FX981_02112	COG3409	Peptidoglycan-binding domain 1 protein
FX981_02112	COG0793	Belongs to the peptidase S41A family
FX981_02114	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FX981_02115	COG1733	regulation of RNA biosynthetic process
FX981_02116	COG0778	Nitroreductase
FX981_02117	COG1113	amino acid transport
FX981_02118	COG0463	Glycosyl transferase, family 2
FX981_02119	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FX981_02120	COG5002	protein histidine kinase activity
FX981_02121	COG0745	RESPONSE REGULATOR receiver
FX981_02123	COG2814	Major facilitator Superfamily
FX981_02124	COG1309	transcriptional regulator
FX981_02125	COG0574	Belongs to the PEP-utilizing enzyme family
FX981_02125	COG3848	Pyruvate phosphate dikinase
FX981_02126	COG4897	Protein conserved in bacteria
FX981_02128	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FX981_02131	COG3595	metallopeptidase activity
FX981_02132	COG1983	PspC domain protein
FX981_02133	COG1950	PFAM Membrane protein of
FX981_02134	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FX981_02136	COG0363	glucosamine-6-phosphate deaminase activity
FX981_02137	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FX981_02138	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FX981_02140	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FX981_02141	COG0546	phosphoglycolate phosphatase activity
FX981_02142	COG0110	maltose O-acetyltransferase activity
FX981_02143	COG1959	2 iron, 2 sulfur cluster binding
FX981_02144	COG2910	NAD(P)H-binding
FX981_02146	COG4990	cell redox homeostasis
FX981_02147	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FX981_02148	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FX981_02149	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FX981_02150	COG0131	Imidazoleglycerol-phosphate dehydratase
FX981_02151	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FX981_02152	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FX981_02153	COG0107	imidazoleglycerol-phosphate synthase activity
FX981_02154	COG0140	phosphoribosyl-ATP diphosphatase activity
FX981_02154	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FX981_02155	COG0457	Tetratricopeptide repeat
FX981_02156	COG0791	NLP P60 protein
FX981_02156	COG3883	PFAM NLP P60 protein
FX981_02157	COG0492	ferredoxin-NADP+ reductase activity
FX981_02158	COG1051	belongs to the nudix hydrolase family
FX981_02159	COG1660	Displays ATPase and GTPase activities
FX981_02160	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FX981_02161	COG1481	regulation of sporulation
FX981_02162	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_02163	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FX981_02165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FX981_02166	COG0288	reversible hydration of carbon dioxide
FX981_02167	COG0659	secondary active sulfate transmembrane transporter activity
FX981_02168	COG1694	Mazg nucleotide pyrophosphohydrolase
FX981_02169	COG1611	Belongs to the LOG family
FX981_02170	COG0740	serine-type endopeptidase activity
FX981_02175	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FX981_02179	COG1819	glycosyl
FX981_02180	COG0747	negative chemotaxis
FX981_02181	COG0601	transmembrane transport
FX981_02186	COG0726	polysaccharide deacetylase
FX981_02187	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_02188	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_02189	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FX981_02191	COG1396	sequence-specific DNA binding
FX981_02192	COG3944	biosynthesis protein
FX981_02193	COG0489	protein tyrosine kinase activity
FX981_02194	COG1086	Polysaccharide biosynthesis protein
FX981_02195	COG0438	transferase activity, transferring glycosyl groups
FX981_02196	COG1215	transferase activity, transferring glycosyl groups
FX981_02197	COG0438	transferase activity, transferring glycosyl groups
FX981_02199	COG1216	Glycosyl transferase, family 2
FX981_02200	COG5039	Polysaccharide pyruvyl transferase
FX981_02201	COG2244	polysaccharide biosynthetic process
FX981_02202	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FX981_02203	COG0110	maltose O-acetyltransferase activity
FX981_02204	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FX981_02205	COG0747	negative chemotaxis
FX981_02206	COG0601	transmembrane transport
FX981_02207	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FX981_02208	COG0444	Belongs to the ABC transporter superfamily
FX981_02210	COG0534	Mate efflux family protein
FX981_02212	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FX981_02213	COG2186	Transcriptional regulator
FX981_02214	COG3829	transcription factor binding
FX981_02215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FX981_02216	COG0833	amino acid
FX981_02218	COG2390	Transcriptional regulator
FX981_02219	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FX981_02220	COG0126	phosphoglycerate kinase activity
FX981_02221	COG0149	triose-phosphate isomerase activity
FX981_02222	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FX981_02223	COG0148	phosphopyruvate hydratase activity
FX981_02225	COG1122	ATPase activity
FX981_02229	COG0456	acetyltransferase
FX981_02231	COG2095	MarC family integral membrane protein
FX981_02232	COG1510	regulation of RNA biosynthetic process
FX981_02233	COG0517	IMP dehydrogenase activity
FX981_02233	COG1125	glycine betaine transport
FX981_02234	COG1174	glycine betaine transport
FX981_02235	COG1732	Glycine betaine
FX981_02236	COG1174	glycine betaine transport
FX981_02237	COG1733	regulation of RNA biosynthetic process
FX981_02238	COG1396	sequence-specific DNA binding
FX981_02239	COG1396	sequence-specific DNA binding
FX981_02240	COG1476	TRANSCRIPTIONal
FX981_02241	COG2002	toxin-antitoxin pair type II binding
FX981_02242	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FX981_02243	COG1647	Serine aminopeptidase, S33
FX981_02244	COG0557	exoribonuclease II activity
FX981_02245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FX981_02255	COG0745	RESPONSE REGULATOR receiver
FX981_02255	COG3706	GGDEF domain
FX981_02257	COG1937	Protein conserved in bacteria
FX981_02258	COG2608	mercury ion transmembrane transporter activity
FX981_02259	COG2217	Heavy metal translocating P-type atpase
FX981_02262	COG1027	Aspartate ammonia-lyase
FX981_02263	COG4191	Histidine kinase
FX981_02264	COG0784	Response regulator, receiver
FX981_02265	COG3226	Transcriptional regulator
FX981_02267	COG0803	Belongs to the bacterial solute-binding protein 9 family
FX981_02268	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FX981_02269	COG1121	(ABC) transporter
FX981_02270	COG2217	Heavy metal translocating P-type atpase
FX981_02271	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FX981_02272	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FX981_02273	COG2860	membrane
FX981_02274	COG0025	NhaP-type Na H and K H
FX981_02275	COG1940	carbohydrate kinase activity
FX981_02276	COG0656	L-ascorbic acid biosynthetic process
FX981_02277	COG4149	molybdate abc transporter
FX981_02278	COG0725	ABC transporter, periplasmic molybdate-binding protein
FX981_02279	COG1368	sulfuric ester hydrolase activity
FX981_02280	COG1988	membrane-bound metal-dependent
FX981_02283	COG0531	amino acid
FX981_02284	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FX981_02285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_02286	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_02287	COG1120	ATPase activity
FX981_02288	COG0745	RESPONSE REGULATOR receiver
FX981_02289	COG2205	protein histidine kinase activity
FX981_02290	COG1904	glucuronate isomerase
FX981_02291	COG1609	Transcriptional regulator
FX981_02292	COG0246	Mannitol dehydrogenase
FX981_02293	COG2721	sulfolactate sulfo-lyase activity
FX981_02295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FX981_02296	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_02297	COG1120	ATPase activity
FX981_02299	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FX981_02300	COG1454	alcohol dehydrogenase
FX981_02303	COG2204	response regulator
FX981_02305	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FX981_02306	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_02307	COG2096	Adenosyltransferase
FX981_02308	COG4758	membrane
FX981_02309	COG1842	Phage shock protein A
FX981_02311	COG4758	membrane
FX981_02312	COG4585	Histidine kinase
FX981_02313	COG2197	response regulator
FX981_02316	COG0814	amino acid
FX981_02317	COG0697	spore germination
FX981_02319	COG0114	fumarate hydratase activity
FX981_02321	COG1309	transcriptional regulator
FX981_02323	COG2770	Histidine kinase
FX981_02323	COG2205	protein histidine kinase activity
FX981_02324	COG0745	RESPONSE REGULATOR receiver
FX981_02325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FX981_02326	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_02328	COG1120	ATPase activity
FX981_02330	COG5577	PFAM Coat F domain
FX981_02333	COG1250	3-hydroxyacyl-CoA dehydrogenase
FX981_02333	COG1024	Enoyl-CoA hydratase
FX981_02334	COG0183	Belongs to the thiolase family
FX981_02335	COG1960	acyl-CoA dehydrogenase activity
FX981_02336	COG1393	Belongs to the ArsC family
FX981_02337	COG0509	glycine decarboxylation via glycine cleavage system
FX981_02339	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FX981_02340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_02342	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FX981_02343	COG2011	ABC-type metal ion transport system permease component
FX981_02344	COG1464	Belongs to the NlpA lipoprotein family
FX981_02345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FX981_02346	COG0396	ATPase activity
FX981_02347	COG0719	Fe-S assembly protein
FX981_02348	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FX981_02349	COG0822	iron-sulfur transferase activity
FX981_02350	COG0719	Fe-S assembly protein
FX981_02353	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FX981_02355	COG2311	Membrane
FX981_02356	COG0745	RESPONSE REGULATOR receiver
FX981_02357	COG5002	protein histidine kinase activity
FX981_02357	COG0642	Histidine kinase
FX981_02359	COG0561	phosphatase activity
FX981_02362	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FX981_02363	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_02364	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FX981_02366	COG2356	endonuclease I
FX981_02367	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FX981_02368	COG2814	Major facilitator Superfamily
FX981_02369	COG2140	Oxalate decarboxylase
FX981_02370	COG2508	Transcriptional regulator
FX981_02371	COG1801	Protein of unknown function DUF72
FX981_02372	COG0737	Belongs to the 5'-nucleotidase family
FX981_02373	COG3377	Domain of unknown function (DUF1805)
FX981_02375	COG0739	heme binding
FX981_02376	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FX981_02378	COG4470	Protein conserved in bacteria
FX981_02379	COG2445	Protein of unknown function DUF86
FX981_02380	COG0647	UMP catabolic process
FX981_02381	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FX981_02382	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FX981_02383	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FX981_02384	COG0460	homoserine dehydrogenase
FX981_02385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FX981_02386	COG0083	homoserine kinase activity
FX981_02387	COG4946	Tricorn protease homolog
FX981_02387	COG0823	Involved in the tonB-independent uptake of proteins
FX981_02387	COG1506	peptidase
FX981_02388	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FX981_02389	COG4837	Protein of unknown function (DUF1462)
FX981_02391	COG1252	NADH dehydrogenase
FX981_02392	COG4844	belongs to the
FX981_02393	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FX981_02394	COG0316	Belongs to the HesB IscA family
FX981_02395	COG0789	Transcriptional regulator
FX981_02397	COG0492	ferredoxin-NADP+ reductase activity
FX981_02398	COG1252	NADH dehydrogenase
FX981_02401	COG3584	3D domain protein
FX981_02402	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FX981_02403	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FX981_02404	COG2056	Na+-H+ antiporter family
FX981_02405	COG4326	sporulation control protein
FX981_02406	COG1268	BioY protein
FX981_02407	COG0686	Belongs to the AlaDH PNT family
FX981_02408	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FX981_02408	COG2508	Transcriptional regulator
FX981_02409	COG4842	Belongs to the WXG100 family
FX981_02410	COG5417	Belongs to the EsaB family
FX981_02411	COG4499	WXG100 protein secretion system (Wss), protein YukC
FX981_02412	COG0433	COG0433 Predicted ATPase
FX981_02412	COG1674	ftsk spoiiie
FX981_02413	COG1511	domain protein
FX981_02415	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_02416	COG1418	mRNA catabolic process
FX981_02419	COG0628	permease
FX981_02423	COG5506	Protein of unknown function (DUF1694)
FX981_02424	COG1335	isochorismatase
FX981_02425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FX981_02426	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FX981_02429	COG0142	geranyltranstransferase activity
FX981_02431	COG4585	Histidine kinase
FX981_02432	COG2197	response regulator
FX981_02433	COG2050	protein possibly involved in aromatic compounds catabolism
FX981_02434	COG1320	monovalent cation:proton antiporter activity
FX981_02435	COG2212	antiporter activity
FX981_02436	COG1863	multisubunit Na H antiporter MnhE subunit
FX981_02437	COG0651	ATP synthesis coupled electron transport
FX981_02438	COG1006	Multisubunit Na H antiporter MnhC subunit
FX981_02439	COG2111	Na H antiporter
FX981_02440	COG2111	Na H antiporter
FX981_02440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FX981_02442	COG3493	citrate carrier protein
FX981_02447	COG4565	transcriptional regulatory protein
FX981_02448	COG3290	protein histidine kinase activity
FX981_02450	COG3011	Protein conserved in bacteria
FX981_02451	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FX981_02452	COG2814	Major facilitator Superfamily
FX981_02453	COG5018	Exonuclease
FX981_02456	COG2205	protein histidine kinase activity
FX981_02457	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FX981_02458	COG2267	carboxylic ester hydrolase activity
FX981_02459	COG1522	sequence-specific DNA binding
FX981_02460	COG0436	Aminotransferase
FX981_02461	COG1098	S1 RNA binding domain
FX981_02462	COG2155	Conserved Protein
FX981_02463	COG1979	alcohol dehydrogenase
FX981_02464	COG1979	alcohol dehydrogenase
FX981_02465	COG0166	Belongs to the GPI family
FX981_02468	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FX981_02470	COG2738	Putative neutral zinc metallopeptidase
FX981_02471	COG1253	flavin adenine dinucleotide binding
FX981_02472	COG0432	Pfam Uncharacterised protein family UPF0047
FX981_02473	COG2070	2-Nitropropane dioxygenase
FX981_02476	COG0840	transmembrane signaling receptor activity
FX981_02477	COG0840	transmembrane signaling receptor activity
FX981_02478	COG0840	transmembrane signaling receptor activity
FX981_02479	COG0840	transmembrane signaling receptor activity
FX981_02480	COG0693	protein deglycase activity
FX981_02481	COG0673	inositol 2-dehydrogenase activity
FX981_02483	COG0628	permease
FX981_02484	COG1968	undecaprenyl-diphosphatase activity
FX981_02486	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FX981_02488	COG1396	sequence-specific DNA binding
FX981_02492	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FX981_02494	COG1595	DNA-templated transcription, initiation
FX981_02495	COG5484	DNA packaging
FX981_02496	COG1783	phage Terminase large subunit
FX981_02497	COG5518	Phage portal protein
FX981_02498	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FX981_02499	COG4653	Phage capsid family
FX981_02508	COG5280	Phage tail tape measure protein TP901
FX981_02508	COG3953	SLT domain
FX981_02508	COG5280	Phage tail tape measure protein TP901
FX981_02508	COG3953	SLT domain
FX981_02509	COG1652	LysM domain
FX981_02510	COG4193	domain, Protein
FX981_02512	COG3628	GPW Gp25 family protein
FX981_02513	COG3299	homolog of phage Mu protein gp47
FX981_02514	COG3778	Protein conserved in bacteria
FX981_02526	COG3409	Peptidoglycan-binding domain 1 protein
FX981_02526	COG5632	N-Acetylmuramoyl-L-alanine amidase
FX981_02528	COG1510	regulation of RNA biosynthetic process
FX981_02530	COG1454	alcohol dehydrogenase
FX981_02531	COG2318	DinB family
FX981_02532	COG1585	Membrane protein implicated in regulation of membrane protease activity
FX981_02533	COG2268	Band 7 protein
FX981_02534	COG0772	Belongs to the SEDS family
FX981_02535	COG0772	Belongs to the SEDS family
FX981_02536	COG3339	Conserved Protein
FX981_02537	COG1247	-acetyltransferase
FX981_02539	COG3859	Proton-coupled thiamine transporter YuaJ
FX981_02565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FX981_02566	COG1575	Belongs to the MenA family. Type 1 subfamily
FX981_02567	COG1169	isochorismate synthase
FX981_02568	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FX981_02569	COG0596	Alpha beta hydrolase
FX981_02570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FX981_02571	COG0318	PFAM AMP-dependent synthetase and ligase
FX981_02572	COG4948	Mandelate Racemase Muconate Lactonizing
FX981_02575	COG1294	oxidase, subunit
FX981_02576	COG1271	oxidase subunit
FX981_02577	COG0254	rRNA binding
FX981_02578	COG3443	Belongs to the bacterial solute-binding protein 9 family
FX981_02578	COG0803	Belongs to the bacterial solute-binding protein 9 family
FX981_02579	COG0288	reversible hydration of carbon dioxide
FX981_02580	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FX981_02581	COG1854	S-ribosylhomocysteine lyase activity
FX981_02584	COG0783	Belongs to the Dps family
FX981_02586	COG4824	toxin secretion phage lysis holin
FX981_02589	COG2310	stress, protein
FX981_02590	COG0494	nUDIX hydrolase
FX981_02591	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FX981_02592	COG1116	anion transmembrane transporter activity
FX981_02593	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FX981_02597	COG1233	COG1233 Phytoene dehydrogenase and related
FX981_02598	COG1506	peptidase
FX981_02600	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FX981_02601	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FX981_02602	COG0367	asparagine synthase
FX981_02603	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FX981_02604	COG2267	carboxylic ester hydrolase activity
FX981_02606	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FX981_02607	COG1242	4 iron, 4 sulfur cluster binding
FX981_02610	COG1725	Transcriptional regulator
FX981_02611	COG1131	(ABC) transporter
FX981_02613	COG1136	(ABC) transporter
FX981_02614	COG0577	efflux transmembrane transporter activity
FX981_02615	COG2433	Pfam Transposase IS66
FX981_02616	COG2202	Pas domain
FX981_02616	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_02618	COG0495	leucyl-tRNA aminoacylation
FX981_02619	COG1073	alpha beta
FX981_02620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FX981_02621	COG0395	ABC-type sugar transport system, permease component
FX981_02622	COG1653	transport
FX981_02623	COG0656	L-ascorbic acid biosynthetic process
FX981_02624	COG2814	Major facilitator Superfamily
FX981_02625	COG1733	regulation of RNA biosynthetic process
FX981_02626	COG2207	Transcriptional regulator
FX981_02627	COG4209	transmembrane transport
FX981_02628	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FX981_02629	COG1653	transport
FX981_02630	COG0673	inositol 2-dehydrogenase activity
FX981_02631	COG5578	integral membrane protein
FX981_02632	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FX981_02634	COG3196	Protein conserved in bacteria
FX981_02635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FX981_02637	COG2081	HI0933 family
FX981_02638	COG2244	polysaccharide biosynthetic process
FX981_02639	COG1187	pseudouridine synthase activity
FX981_02640	COG1349	DNA-binding transcription factor activity
FX981_02641	COG2252	PERMEase
FX981_02642	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FX981_02643	COG3340	Belongs to the peptidase S51 family
FX981_02644	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FX981_02645	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FX981_02647	COG1597	lipid kinase activity
FX981_02648	COG0510	thiamine kinase activity
FX981_02650	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FX981_02651	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FX981_02652	COG0281	malic enzyme
FX981_02653	COG5584	Small secreted protein
FX981_02654	COG1363	Peptidase, m42
FX981_02657	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_02658	COG4848	Belongs to the UPF0354 family
FX981_02659	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FX981_02660	COG1674	ftsk spoiiie
FX981_02661	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FX981_02662	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FX981_02663	COG4980	gas vesicle protein
FX981_02664	COG3118	belongs to the thioredoxin family
FX981_02665	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FX981_02665	COG1605	Chorismate mutase
FX981_02666	COG1609	Transcriptional regulator
FX981_02667	COG0123	including yeast histone deacetylase and acetoin utilization protein
FX981_02668	COG0517	IMP dehydrogenase activity
FX981_02669	COG0454	-acetyltransferase
FX981_02670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FX981_02671	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FX981_02672	COG2329	Antibiotic biosynthesis monooxygenase
FX981_02673	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FX981_02676	COG1335	isochorismatase
FX981_02677	COG1335	isochorismatase
FX981_02679	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FX981_02680	COG1956	GAF domain-containing protein
FX981_02681	COG1309	transcriptional regulator
FX981_02682	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FX981_02683	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FX981_02684	COG1114	Component of the transport system for branched-chain amino acids
FX981_02685	COG1114	Component of the transport system for branched-chain amino acids
FX981_02686	COG1104	cysteine desulfurase activity
FX981_02687	COG0301	tRNA thio-modification
FX981_02689	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FX981_02690	COG1279	arginine transmembrane transporter activity
FX981_02693	COG0402	S-adenosylhomocysteine deaminase activity
FX981_02694	COG0577	efflux transmembrane transporter activity
FX981_02695	COG1136	(ABC) transporter
FX981_02696	COG2205	protein histidine kinase activity
FX981_02697	COG0745	RESPONSE REGULATOR receiver
FX981_02698	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FX981_02699	COG2197	response regulator
FX981_02700	COG4585	Histidine kinase
FX981_02701	COG3239	Fatty acid desaturase
FX981_02703	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FX981_02704	COG0616	signal peptide processing
FX981_02705	COG1714	RDD family
FX981_02707	COG3874	Sporulation protein YtfJ
FX981_02708	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FX981_02709	COG0827	DNA restriction-modification system
FX981_02710	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FX981_02711	COG0521	Mo-molybdopterin cofactor biosynthetic process
FX981_02712	COG0137	argininosuccinate synthase activity
FX981_02713	COG0165	Argininosuccinate lyase
FX981_02715	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_02716	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FX981_02717	COG4109	DRTGG domain
FX981_02719	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FX981_02723	COG0587	DNA-directed DNA polymerase activity
FX981_02724	COG0281	malic enzyme
FX981_02725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FX981_02726	COG0825	malonyl-CoA metabolic process
FX981_02727	COG0205	6-phosphofructokinase activity
FX981_02729	COG3030	protein affecting phage T7 exclusion by the F plasmid
FX981_02730	COG0628	permease
FX981_02731	COG2707	UPF0756 membrane protein
FX981_02732	COG0372	Belongs to the citrate synthase family
FX981_02733	COG0538	isocitrate dehydrogenase activity
FX981_02734	COG0039	L-malate dehydrogenase activity
FX981_02735	COG0745	RESPONSE REGULATOR receiver
FX981_02736	COG5002	protein histidine kinase activity
FX981_02737	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FX981_02737	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FX981_02738	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FX981_02739	COG1971	Probably functions as a manganese efflux pump
FX981_02740	COG0237	dephospho-CoA kinase activity
FX981_02741	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FX981_02742	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FX981_02744	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FX981_02745	COG3611	Membrane attachment protein
FX981_02746	COG1484	DNA-dependent DNA replication
FX981_02747	COG0398	Pfam SNARE associated Golgi protein
FX981_02749	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FX981_02752	COG3275	phosphorelay sensor kinase activity
FX981_02753	COG3279	Response regulator of the LytR AlgR family
FX981_02755	COG1346	cytolysis
FX981_02756	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FX981_02757	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FX981_02758	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FX981_02759	COG3326	Membrane
FX981_02761	COG1363	Peptidase, m42
FX981_02762	COG1966	Carbon starvation protein
FX981_02764	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FX981_02765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FX981_02766	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FX981_02766	COG0072	phenylalanine-tRNA ligase activity
FX981_02767	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FX981_02768	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FX981_02769	COG1286	toxin biosynthetic process
FX981_02770	COG1796	DNA polymerase
FX981_02770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FX981_02771	COG1193	negative regulation of DNA recombination
FX981_02772	COG3766	membrane
FX981_02774	COG0318	PFAM AMP-dependent synthetase and ligase
FX981_02775	COG1309	transcriptional regulator
FX981_02776	COG1024	Enoyl-CoA hydratase
FX981_02777	COG2086	electron transfer activity
FX981_02778	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FX981_02779	COG3534	alpha-L-arabinofuranosidase
FX981_02780	COG3118	belongs to the thioredoxin family
FX981_02781	COG0322	excinuclease ABC activity
FX981_02782	COG0527	aspartate kinase activity
FX981_02783	COG1719	4-vinyl reductase, 4VR
FX981_02784	COG2009	succinate dehydrogenase
FX981_02785	COG1053	succinate dehydrogenase
FX981_02786	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FX981_02787	COG0824	Thioesterase
FX981_02789	COG2828	Protein conserved in bacteria
FX981_02790	COG0583	DNA-binding transcription factor activity
FX981_02791	COG2851	Citrate transporter
FX981_02792	COG2197	response regulator
FX981_02793	COG1846	Transcriptional regulator
FX981_02794	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FX981_02795	COG5401	PFAM Sporulation and spore germination
FX981_02796	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FX981_02797	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FX981_02798	COG0622	Phosphoesterase
FX981_02801	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_02802	COG0582	viral genome integration into host DNA
FX981_02807	COG5444	nuclease activity
FX981_02810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FX981_02811	COG1696	Membrane protein involved in D-alanine export
FX981_02812	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FX981_02813	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FX981_02814	COG3339	Conserved Protein
FX981_02815	COG2706	6-phosphogluconolactonase activity
FX981_02816	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FX981_02817	COG0028	Belongs to the TPP enzyme family
FX981_02818	COG0440	acetolactate synthase activity
FX981_02819	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FX981_02820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FX981_02821	COG0473	3-isopropylmalate dehydrogenase activity
FX981_02822	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FX981_02823	COG0066	3-isopropylmalate dehydratase activity
FX981_02824	COG0457	Tetratricopeptide repeat
FX981_02824	COG1477	protein flavinylation
FX981_02825	COG0544	peptidyl-prolyl cis-trans isomerase activity
FX981_02826	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FX981_02827	COG1067	ATP-dependent peptidase activity
FX981_02827	COG0470	DNA polymerase III
FX981_02828	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FX981_02829	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FX981_02831	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FX981_02832	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FX981_02833	COG0181	hydroxymethylbilane synthase activity
FX981_02834	COG1587	Uroporphyrinogen-III synthase
FX981_02835	COG0113	porphobilinogen synthase activity
FX981_02836	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FX981_02837	COG1388	LysM domain
FX981_02838	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FX981_02840	COG0525	valine-tRNA ligase activity
FX981_02841	COG0285	dihydrofolate synthase activity
FX981_02842	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FX981_02844	COG0424	maF-like protein
FX981_02845	COG2003	Belongs to the UPF0758 family
FX981_02846	COG1077	Cell shape determining protein MreB Mrl
FX981_02847	COG1792	Involved in formation and maintenance of cell shape
FX981_02848	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FX981_02849	COG0850	regulation of cytokinetic process
FX981_02850	COG2894	cell division
FX981_02851	COG0739	heme binding
FX981_02852	COG1994	Peptidase M50
FX981_02853	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FX981_02854	COG2868	ribosomal protein
FX981_02855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FX981_02856	COG3290	protein histidine kinase activity
FX981_02857	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FX981_02858	COG4492	Belongs to the UPF0735 family
FX981_02859	COG0077	Prephenate dehydratase
FX981_02860	COG1827	regulation of RNA biosynthetic process
FX981_02861	COG1104	cysteine desulfurase activity
FX981_02862	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FX981_02863	COG0157	Belongs to the NadC ModD family
FX981_02864	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FX981_02865	COG1388	LysM domain
FX981_02865	COG1388	LysM domain
FX981_02868	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FX981_02871	COG2112	serine threonine protein kinase
FX981_02873	COG0632	four-way junction helicase activity
FX981_02874	COG2255	four-way junction helicase activity
FX981_02876	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FX981_02877	COG0343	queuine tRNA-ribosyltransferase activity
FX981_02878	COG1862	Preprotein translocase
FX981_02880	COG2323	membrane
FX981_02881	COG2244	polysaccharide biosynthetic process
FX981_02883	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FX981_02883	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FX981_02884	COG0490	domain, Protein
FX981_02885	COG5416	Lipopolysaccharide assembly protein A domain
FX981_02886	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FX981_02886	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FX981_02887	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FX981_02888	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FX981_02889	COG1490	D-aminoacyl-tRNA deacylase activity
FX981_02890	COG4991	sh3 domain protein
FX981_02890	COG0860	N-Acetylmuramoyl-L-alanine amidase
FX981_02890	COG3103	Sh3 type 3 domain protein
FX981_02892	COG0124	histidyl-tRNA synthetase
FX981_02894	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FX981_02895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FX981_02896	COG1959	2 iron, 2 sulfur cluster binding
FX981_02897	COG1104	cysteine desulfurase activity
FX981_02898	COG0482	sulfurtransferase activity
FX981_02899	COG0457	Tetratricopeptide repeat
FX981_02900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FX981_02901	COG3881	PFAM PRC-barrel domain
FX981_02904	COG0765	amino acid transport
FX981_02905	COG0765	amino acid transport
FX981_02906	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_02907	COG1126	abc transporter atp-binding protein
FX981_02908	COG0628	permease
FX981_02909	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FX981_02910	COG4472	Bacterial protein of unknown function (DUF965)
FX981_02911	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FX981_02912	COG3906	Belongs to the UPF0473 family
FX981_02913	COG1268	BioY protein
FX981_02914	COG0318	PFAM AMP-dependent synthetase and ligase
FX981_02915	COG0183	Belongs to the thiolase family
FX981_02916	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FX981_02920	COG0572	uridine kinase
FX981_02922	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FX981_02923	COG0768	penicillin binding
FX981_02926	COG2226	methyltransferase
FX981_02927	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FX981_02928	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FX981_02929	COG0626	cystathionine gamma-synthase activity
FX981_02934	COG2226	methyltransferase
FX981_02935	COG1063	alcohol dehydrogenase
FX981_02936	COG2226	methyltransferase
FX981_02937	COG1131	(ABC) transporter
FX981_02938	COG0842	Transport permease protein
FX981_02938	COG1511	domain protein
FX981_02939	COG0842	Transport permease protein
FX981_02940	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_02942	COG1063	alcohol dehydrogenase
FX981_02943	COG3546	catalase activity
FX981_02945	COG0765	amino acid transport
FX981_02947	COG1126	abc transporter atp-binding protein
FX981_02948	COG1960	acyl-CoA dehydrogenase activity
FX981_02949	COG2602	Beta-lactamase
FX981_02950	COG0109	protoheme IX farnesyltransferase activity
FX981_02951	COG1309	transcriptional regulator
FX981_02956	COG1733	regulation of RNA biosynthetic process
FX981_02957	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FX981_02958	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FX981_02960	COG1609	Transcriptional regulator
FX981_02963	COG2160	L-arabinose isomerase activity
FX981_02969	COG0726	polysaccharide deacetylase
FX981_02974	COG2318	DinB family
FX981_02976	COG0457	Tetratricopeptide repeat
FX981_02978	COG2755	lipolytic protein G-D-S-L family
FX981_02980	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FX981_02981	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FX981_02982	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FX981_02983	COG1534	Rna-binding protein
FX981_02984	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FX981_02985	COG1713	HD superfamily hydrolase involved in NAD metabolism
FX981_02986	COG0799	negative regulation of ribosome biogenesis
FX981_02987	COG2226	methyltransferase
FX981_02988	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FX981_02989	COG1555	photosystem II stabilization
FX981_02990	COG2131	deaminase
FX981_02991	COG0658	competence protein
FX981_02991	COG2333	competence protein COMEC
FX981_02993	COG1466	dna polymerase III delta subunit
FX981_02994	COG0268	Binds directly to 16S ribosomal RNA
FX981_02995	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FX981_02996	COG0860	N-Acetylmuramoyl-L-alanine amidase
FX981_02998	COG0481	GTPase activity
FX981_02999	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FX981_03000	COG1420	regulation of RNA biosynthetic process
FX981_03001	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FX981_03002	COG0443	Heat shock 70 kDa protein
FX981_03003	COG0484	heat shock protein binding
FX981_03004	COG2264	protein methyltransferase activity
FX981_03005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FX981_03006	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FX981_03007	COG1283	sodium-dependent phosphate transmembrane transporter activity
FX981_03008	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FX981_03009	COG1610	YqeY-like protein
FX981_03010	COG1030	water channel activity
FX981_03011	COG4864	UPF0365 protein
FX981_03014	COG0561	phosphatase activity
FX981_03015	COG1702	phosphate starvation-inducible protein PhoH
FX981_03016	COG1480	7TM receptor with intracellular HD hydrolase
FX981_03017	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FX981_03018	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FX981_03019	COG0295	cytidine deaminase activity
FX981_03020	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FX981_03022	COG1381	Involved in DNA repair and RecF pathway recombination
FX981_03023	COG0752	glycyl-tRNA synthetase alpha subunit
FX981_03024	COG0751	glycine-tRNA ligase activity
FX981_03025	COG0517	IMP dehydrogenase activity
FX981_03026	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FX981_03027	COG1671	Belongs to the UPF0178 family
FX981_03028	COG0358	DNA primase activity
FX981_03029	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FX981_03030	COG2010	Cytochrome c
FX981_03031	COG2384	SAM-dependent methyltransferase
FX981_03032	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FX981_03033	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FX981_03035	COG0513	Belongs to the DEAD box helicase family
FX981_03038	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FX981_03039	COG1121	(ABC) transporter
FX981_03040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FX981_03041	COG0735	belongs to the Fur family
FX981_03042	COG1940	carbohydrate kinase activity
FX981_03043	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FX981_03044	COG4709	membrane
FX981_03045	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FX981_03046	COG1388	LysM domain
FX981_03047	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FX981_03048	COG5521	maltodextrose utilization protein MalA
FX981_03049	COG2839	Protein conserved in bacteria
FX981_03050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FX981_03051	COG0477	Major facilitator Superfamily
FX981_03053	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FX981_03054	COG0573	inorganic phosphate transmembrane transporter activity
FX981_03055	COG0581	inorganic phosphate transmembrane transporter activity
FX981_03056	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FX981_03057	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FX981_03058	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FX981_03060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FX981_03061	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FX981_03065	COG0705	Rhomboid family
FX981_03065	COG0457	Tetratricopeptide repeat
FX981_03066	COG4483	Protein conserved in bacteria
FX981_03067	COG1940	carbohydrate kinase activity
FX981_03068	COG1368	sulfuric ester hydrolase activity
FX981_03069	COG2866	Carboxypeptidase
FX981_03070	COG2814	Major facilitator Superfamily
FX981_03071	COG0011	TIGRFAM Protein of
FX981_03073	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FX981_03075	COG1393	Belongs to the ArsC family
FX981_03077	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_03078	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FX981_03079	COG1459	type II secretion system
FX981_03080	COG4537	Required for transformation and DNA binding
FX981_03081	COG4970	Tfp pilus assembly protein FimT
FX981_03088	COG0681	Belongs to the peptidase S26 family
FX981_03093	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FX981_03094	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FX981_03095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FX981_03096	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FX981_03097	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FX981_03098	COG0095	Lipoate-protein ligase
FX981_03099	COG1321	iron dependent repressor
FX981_03100	COG1752	Esterase of the alpha-beta hydrolase superfamily
FX981_03102	COG3872	metal-dependent enzyme
FX981_03104	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FX981_03105	COG0006	proline dipeptidase activity
FX981_03106	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FX981_03108	COG3854	ATPases associated with a variety of cellular activities
FX981_03116	COG0511	ligase activity, forming carbon-carbon bonds
FX981_03117	COG0439	Biotin carboxylase
FX981_03118	COG1302	Protein conserved in bacteria
FX981_03119	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FX981_03120	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FX981_03121	COG1570	exodeoxyribonuclease VII activity
FX981_03122	COG1722	exodeoxyribonuclease VII activity
FX981_03123	COG0142	geranyltranstransferase activity
FX981_03124	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FX981_03125	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FX981_03126	COG1438	arginine binding
FX981_03127	COG0497	DNA recombination
FX981_03128	COG0750	zinc metalloprotease
FX981_03129	COG0745	RESPONSE REGULATOR receiver
FX981_03131	COG0457	Tetratricopeptide repeat
FX981_03133	COG0584	glycerophosphoryl diester phosphodiesterase
FX981_03135	COG3829	transcription factor binding
FX981_03135	COG3290	protein histidine kinase activity
FX981_03136	COG0280	phosphate acetyltransferase
FX981_03137	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FX981_03138	COG3426	butyrate kinase activity
FX981_03139	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FX981_03140	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FX981_03141	COG0022	dehydrogenase e1 component
FX981_03142	COG0508	dehydrogenase complex catalyzes the overall conversion of
FX981_03144	COG1597	lipid kinase activity
FX981_03146	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FX981_03147	COG0765	amino acid transport
FX981_03148	COG1126	abc transporter atp-binding protein
FX981_03149	COG4129	membrane
FX981_03150	COG1376	ErfK ybiS ycfS ynhG family protein
FX981_03151	COG0346	lactoylglutathione lyase activity
FX981_03152	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FX981_03153	COG2195	Cleaves the N-terminal amino acid of tripeptides
FX981_03155	COG0706	membrane insertase activity
FX981_03158	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FX981_03159	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FX981_03161	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_03162	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FX981_03163	COG1447	Phosphotransferase system cellobiose-specific component IIA
FX981_03164	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FX981_03165	COG2723	6-phospho-beta-galactosidase activity
FX981_03166	COG2188	Transcriptional regulator
FX981_03167	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FX981_03169	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FX981_03170	COG0596	Alpha beta hydrolase
FX981_03171	COG1902	pentaerythritol trinitrate reductase activity
FX981_03172	COG4187	Peptidase family M20/M25/M40
FX981_03173	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FX981_03177	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FX981_03178	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FX981_03179	COG0300	oxidoreductase activity
FX981_03180	COG0446	pyridine nucleotide-disulphide oxidoreductase
FX981_03181	COG1072	(Pantothenic acid kinase))
FX981_03182	COG2211	Major facilitator Superfamily
FX981_03184	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FX981_03186	COG0456	acetyltransferase
FX981_03187	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FX981_03187	COG0456	acetyltransferase
FX981_03188	COG4918	Iron-sulphur cluster biosynthesis
FX981_03190	COG0457	Tetratricopeptide repeat
FX981_03191	COG1073	alpha beta
FX981_03194	COG0667	Aldo Keto reductase
FX981_03195	COG0494	nUDIX hydrolase
FX981_03196	COG1379	DNA repair
FX981_03197	COG2153	protein acetylation
FX981_03199	COG1404	Belongs to the peptidase S8 family
FX981_03200	COG1300	Membrane
FX981_03201	COG0735	belongs to the Fur family
FX981_03203	COG4974	Belongs to the 'phage' integrase family
FX981_03204	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FX981_03205	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FX981_03206	COG1686	Belongs to the peptidase S11 family
FX981_03208	COG2172	sigma factor antagonist activity
FX981_03209	COG1191	sigma factor activity
FX981_03213	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FX981_03216	COG0697	spore germination
FX981_03217	COG0019	diaminopimelate decarboxylase activity
FX981_03218	COG4086	secreted protein
FX981_03219	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FX981_03220	COG2814	Major facilitator Superfamily
FX981_03224	COG0307	riboflavin synthase, alpha
FX981_03225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FX981_03225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FX981_03226	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FX981_03227	COG0456	acetyltransferase
FX981_03228	COG1547	Domain of unknown function (DUF309)
FX981_03230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FX981_03231	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FX981_03233	COG1686	Belongs to the peptidase S11 family
FX981_03234	COG2715	membrane protein required for spore maturation
FX981_03235	COG0700	Nucleoside recognition
FX981_03236	COG1187	pseudouridine synthase activity
FX981_03237	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_03238	COG1333	cytochrome c biogenesis protein
FX981_03239	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FX981_03240	COG0745	RESPONSE REGULATOR receiver
FX981_03241	COG5002	protein histidine kinase activity
FX981_03242	COG1595	DNA-templated transcription, initiation
FX981_03244	COG3409	Peptidoglycan-binding domain 1 protein
FX981_03244	COG5632	N-Acetylmuramoyl-L-alanine amidase
FX981_03245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FX981_03246	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FX981_03247	COG1141	Ferredoxin
FX981_03248	COG4955	Helix-turn-helix domain
FX981_03249	COG0514	ATP-dependent DNA helicase (RecQ)
FX981_03250	COG1266	CAAX protease self-immunity
FX981_03251	COG1388	LysM domain
FX981_03253	COG1408	metallophosphoesterase
FX981_03254	COG4862	establishment of competence for transformation
FX981_03255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FX981_03256	COG0492	ferredoxin-NADP+ reductase activity
FX981_03257	COG2339	peptidase activity
FX981_03258	COG3773	Cell wall hydrolase
FX981_03258	COG3409	Peptidoglycan-binding domain 1 protein
FX981_03259	COG2959	enzyme of heme biosynthesis
FX981_03260	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FX981_03262	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FX981_03263	COG0539	negative regulation of cytoplasmic translation
FX981_03264	COG1304	FMN binding
FX981_03269	COG1160	GTP binding
FX981_03270	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FX981_03273	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FX981_03274	COG0776	regulation of translation
FX981_03275	COG0302	gtp cyclohydrolase
FX981_03277	COG0142	geranyltranstransferase activity
FX981_03278	COG2226	methyltransferase
FX981_03279	COG0142	geranyltranstransferase activity
FX981_03280	COG0105	UTP biosynthetic process
FX981_03281	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FX981_03282	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FX981_03283	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FX981_03284	COG4401	Chorismate mutase type I
FX981_03287	COG0134	indole-3-glycerol-phosphate synthase activity
FX981_03289	COG0133	tryptophan synthase activity
FX981_03290	COG0159	tryptophan synthase activity
FX981_03291	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FX981_03292	COG0287	Prephenate dehydrogenase
FX981_03293	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FX981_03294	COG0457	Tetratricopeptide repeat
FX981_03295	COG5582	Belongs to the UPF0302 family
FX981_03297	COG0723	plastoquinol--plastocyanin reductase activity
FX981_03298	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FX981_03299	COG2010	Cytochrome c
FX981_03299	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FX981_03300	COG4347	Protein of unknown function (DUF1405)
FX981_03302	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FX981_03303	COG1694	Mazg nucleotide pyrophosphohydrolase
FX981_03304	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FX981_03305	COG1803	Methylglyoxal synthase
FX981_03306	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FX981_03307	COG0438	transferase activity, transferring glycosyl groups
FX981_03308	COG0617	tRNA 3'-terminal CCA addition
FX981_03310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FX981_03311	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FX981_03312	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FX981_03313	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FX981_03313	COG1199	ATP-dependent helicase activity
FX981_03315	COG5353	protein conserved in bacteria
FX981_03316	COG0017	Asparaginyl-tRNA synthetase
FX981_03317	COG3935	DnaD domain protein
FX981_03318	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FX981_03320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FX981_03320	COG4499	WXG100 protein secretion system (Wss), protein YukC
FX981_03321	COG3331	DNA recombination
FX981_03327	COG0071	Belongs to the small heat shock protein (HSP20) family
FX981_03328	COG2190	(PTS) system
FX981_03329	COG1902	pentaerythritol trinitrate reductase activity
FX981_03330	COG1111	helicase
FX981_03330	COG1205	dead DEAH box helicase
FX981_03331	COG3359	exonuclease
FX981_03334	COG4474	Belongs to the UPF0398 family
FX981_03335	COG3599	regulation of cell shape
FX981_03336	COG0116	Belongs to the methyltransferase superfamily
FX981_03338	COG1199	ATP-dependent helicase activity
FX981_03339	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FX981_03340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FX981_03341	COG2233	PERMEase
FX981_03342	COG0726	polysaccharide deacetylase
FX981_03344	COG3424	synthase
FX981_03345	COG1755	Isoprenylcysteine carboxyl methyltransferase
FX981_03346	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FX981_03349	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FX981_03351	COG0328	RNA-DNA hybrid ribonuclease activity
FX981_03352	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FX981_03353	COG0328	RNA-DNA hybrid ribonuclease activity
FX981_03356	COG1278	Cold shock
FX981_03358	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FX981_03359	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FX981_03360	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FX981_03361	COG0386	Belongs to the glutathione peroxidase family
FX981_03362	COG1418	mRNA catabolic process
FX981_03363	COG1413	lyase activity
FX981_03364	COG0129	dihydroxy-acid dehydratase activity
FX981_03366	COG2521	methyltransferase
FX981_03366	COG2136	Putative SAM-dependent methyltransferase
FX981_03368	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FX981_03369	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FX981_03370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FX981_03371	COG0204	Acyl-transferase
FX981_03372	COG1272	protein, Hemolysin III
FX981_03373	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FX981_03374	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FX981_03377	COG1999	signal sequence binding
FX981_03378	COG2755	lipolytic protein G-D-S-L family
FX981_03379	COG4698	Protein conserved in bacteria
FX981_03383	COG1846	Transcriptional regulator
FX981_03384	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FX981_03385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FX981_03386	COG1086	Polysaccharide biosynthesis protein
FX981_03388	COG4641	Protein conserved in bacteria
FX981_03391	COG0463	Glycosyl transferase, family 2
FX981_03392	COG3829	transcription factor binding
FX981_03393	COG1509	lysine 2,3-aminomutase activity
FX981_03395	COG4479	Belongs to the UPF0346 family
FX981_03398	COG0671	phosphoesterase, PA-phosphatase related
FX981_03400	COG0813	purine-nucleoside phosphorylase activity
FX981_03401	COG1876	peptidase activity
FX981_03403	COG2226	methyltransferase
FX981_03404	COG0793	Belongs to the peptidase S41A family
FX981_03404	COG3409	Peptidoglycan-binding domain 1 protein
FX981_03405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FX981_03407	COG0778	Nitroreductase
FX981_03408	COG1733	regulation of RNA biosynthetic process
FX981_03411	COG2962	Rard protein
FX981_03413	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FX981_03414	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FX981_03415	COG0534	Mate efflux family protein
FX981_03417	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FX981_03418	COG1388	LysM domain
FX981_03418	COG0791	NLP P60 protein
FX981_03419	COG2032	superoxide dismutase activity
FX981_03420	COG0714	Associated with various cellular activities
FX981_03421	COG4548	von Willebrand factor, type A
FX981_03422	COG0567	Dehydrogenase, E1 component
FX981_03423	COG0508	dehydrogenase complex catalyzes the overall conversion of
FX981_03424	COG0385	Bile acid
FX981_03425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FX981_03426	COG1657	PFAM Prenyltransferase squalene oxidase
FX981_03427	COG1012	belongs to the aldehyde dehydrogenase family
FX981_03432	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FX981_03433	COG0514	ATP-dependent DNA helicase (RecQ)
FX981_03434	COG3584	3D domain protein
FX981_03434	COG1388	LysM domain
FX981_03436	COG2322	membrane
FX981_03437	COG0372	Belongs to the citrate synthase family
FX981_03438	COG2079	MmgE PrpD family protein
FX981_03439	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FX981_03440	COG0741	lytic transglycosylase activity
FX981_03441	COG0531	amino acid
FX981_03442	COG0640	Transcriptional regulator
FX981_03444	COG2378	regulation of single-species biofilm formation
FX981_03445	COG3708	Transcriptional regulator
FX981_03446	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FX981_03447	COG1309	transcriptional regulator
FX981_03451	COG1994	Peptidase M50
FX981_03452	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FX981_03453	COG2211	Major facilitator Superfamily
FX981_03456	COG2115	Belongs to the xylose isomerase family
FX981_03457	COG1070	Carbohydrate kinase
FX981_03459	COG0243	molybdopterin cofactor binding
FX981_03462	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FX981_03463	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FX981_03464	COG0454	-acetyltransferase
FX981_03465	COG4978	Transcriptional regulator
FX981_03465	COG0789	Transcriptional regulator
FX981_03466	COG1132	(ABC) transporter
FX981_03468	COG0583	DNA-binding transcription factor activity
FX981_03469	COG0070	glutamate synthase
FX981_03469	COG0067	glutamate synthase
FX981_03469	COG0069	glutamate synthase activity
FX981_03470	COG0493	'glutamate synthase
FX981_03471	COG2223	nitrite transmembrane transporter activity
FX981_03472	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FX981_03473	COG0243	molybdopterin cofactor binding
FX981_03474	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FX981_03475	COG2146	nitrite reductase [NAD(P)H] activity
FX981_03476	COG2323	membrane
FX981_03477	COG4677	pectinesterase activity
FX981_03478	COG2027	D-alanyl-D-alanine carboxypeptidase
FX981_03479	COG0534	Mate efflux family protein
FX981_03482	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FX981_03484	COG1587	Uroporphyrinogen-III synthase
FX981_03485	COG0586	Pfam SNARE associated Golgi protein
FX981_03486	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FX981_03487	COG2246	polysaccharide biosynthetic process
FX981_03488	COG0166	Belongs to the GPI family
FX981_03495	COG0247	lactate metabolic process
FX981_03496	COG0277	FAD linked oxidase domain protein
FX981_03497	COG3835	regulator
FX981_03499	COG1349	DNA-binding transcription factor activity
FX981_03501	COG1649	PFAM Uncharacterised BCR, COG1649
FX981_03502	COG1960	acyl-CoA dehydrogenase activity
FX981_03503	COG0318	PFAM AMP-dependent synthetase and ligase
FX981_03504	COG0439	Biotin carboxylase
FX981_03505	COG0511	ligase activity, forming carbon-carbon bonds
FX981_03506	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FX981_03507	COG1024	Enoyl-CoA hydratase
FX981_03508	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FX981_03509	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FX981_03510	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FX981_03511	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FX981_03513	COG1012	belongs to the aldehyde dehydrogenase family
FX981_03517	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FX981_03519	COG1105	Belongs to the carbohydrate kinase PfkB family
FX981_03520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_03520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_03520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_03521	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_03521	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_03521	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FX981_03523	COG2814	Major facilitator Superfamily
FX981_03524	COG1846	Transcriptional regulator
FX981_03525	COG5444	nuclease activity
FX981_03533	COG1053	succinate dehydrogenase
FX981_03534	COG0583	DNA-binding transcription factor activity
FX981_03535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FX981_03538	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FX981_03543	COG1486	melibiose metabolic process
FX981_03545	COG1082	Xylose isomerase domain protein TIM barrel
FX981_03546	COG2814	Major facilitator Superfamily
FX981_03547	COG0191	fructose-bisphosphate aldolase activity
FX981_03548	COG1349	DNA-binding transcription factor activity
FX981_03549	COG3962	Belongs to the TPP enzyme family
FX981_03550	COG3718	enzyme involved in inositol metabolism
FX981_03552	COG1012	belongs to the aldehyde dehydrogenase family
FX981_03553	COG0673	inositol 2-dehydrogenase activity
FX981_03554	COG3507	Belongs to the glycosyl hydrolase 43 family
FX981_03556	COG0745	RESPONSE REGULATOR receiver
FX981_03557	COG2205	protein histidine kinase activity
FX981_03560	COG2190	(PTS) system
FX981_03560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FX981_03560	COG1263	PTS System
FX981_03561	COG2723	6-phospho-beta-galactosidase activity
FX981_03562	COG0789	Transcriptional regulator
FX981_03563	COG0657	acetylesterase activity
FX981_03565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FX981_03575	COG0251	oxidation-reduction process
FX981_03576	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FX981_03577	COG2409	Drug exporters of the RND superfamily
FX981_03578	COG4585	Histidine kinase
FX981_03579	COG2197	response regulator
FX981_03580	COG4977	sequence-specific DNA binding
FX981_03580	COG1917	Cupin 2, conserved barrel domain protein
FX981_03581	COG1070	Carbohydrate kinase
FX981_03582	COG4806	L-rhamnose isomerase
FX981_03584	COG0247	lactate metabolic process
FX981_03585	COG1139	Iron-sulfur cluster binding protein
FX981_03587	COG2814	Major facilitator Superfamily
FX981_03588	COG3254	rhamnose metabolic process
FX981_03589	COG1349	DNA-binding transcription factor activity
FX981_03590	COG0235	Class ii aldolase
FX981_03591	COG1012	belongs to the aldehyde dehydrogenase family
FX981_03592	COG1733	regulation of RNA biosynthetic process
FX981_03593	COG2249	NAD(P)H dehydrogenase (quinone) activity
FX981_03594	COG0110	maltose O-acetyltransferase activity
FX981_03595	COG0738	Major facilitator superfamily
FX981_03598	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FX981_03599	COG0187	DNA topoisomerase II activity
FX981_03600	COG1832	CoA-binding protein
FX981_03601	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FX981_03602	COG4841	protein insertion into membrane
FX981_03604	COG0824	Thioesterase
FX981_03608	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FX981_03609	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FX981_03612	COG0071	Belongs to the small heat shock protein (HSP20) family
FX981_03614	COG4846	Membrane protein involved in cytochrome C biogenesis
FX981_03615	COG0785	Cytochrome C biogenesis protein
FX981_03616	COG3763	UPF0154 protein
FX981_03618	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FX981_03619	COG4224	UPF0291 protein
FX981_03620	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FX981_03621	COG1388	LysM domain
FX981_03622	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FX981_03624	COG1366	Belongs to the anti-sigma-factor antagonist family
FX981_03625	COG3209	COG3209 Rhs family protein
FX981_03626	COG3591	Belongs to the peptidase S1B family
FX981_03627	COG2124	cytochrome p450
FX981_03627	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FX981_03628	COG1309	transcriptional regulator
FX981_03629	COG2323	membrane
FX981_03633	COG0702	epimerase
FX981_03634	COG1959	2 iron, 2 sulfur cluster binding
FX981_03635	COG0346	lactoylglutathione lyase activity
FX981_03636	COG4876	unkown
FX981_03637	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FX981_03638	COG3285	dna ligase
FX981_03638	COG1793	dna ligase
FX981_03639	COG3619	membrane
FX981_03641	COG0457	Tetratricopeptide repeat
FX981_03642	COG5646	InterPro IPR014922
FX981_03646	COG5444	nuclease activity
FX981_03648	COG0457	Tetratricopeptide repeat
FX981_03651	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FX981_03653	COG2369	cell adhesion
FX981_03656	COG2801	Transposase and inactivated derivatives
FX981_03660	COG4282	regulation of fungal-type cell wall biogenesis
FX981_03663	COG0174	glutamine synthetase
FX981_03664	COG0789	Transcriptional regulator
FX981_03665	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FX981_03666	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FX981_03667	COG0464	growth
FX981_03668	COG0860	N-Acetylmuramoyl-L-alanine amidase
FX981_03669	COG4112	unkown
FX981_03670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FX981_03671	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FX981_03672	COG1780	Probably involved in ribonucleotide reductase function
FX981_03675	COG1923	regulation of RNA biosynthetic process
FX981_03676	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FX981_03681	COG2076	Multidrug Resistance protein
FX981_03682	COG1764	response to oxidative stress
FX981_03683	COG4195	phage-related replication protein
FX981_03684	COG1404	Belongs to the peptidase S8 family
FX981_03685	COG0457	Tetratricopeptide repeat
FX981_03686	COG4195	phage-related replication protein
FX981_03687	COG1329	Transcriptional regulator
FX981_03690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FX981_03691	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FX981_03693	COG4550	Control of competence regulator ComK, YlbF/YmcA
FX981_03694	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FX981_03695	COG0156	8-amino-7-oxononanoate synthase activity
FX981_03696	COG1063	alcohol dehydrogenase
FX981_03697	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FX981_03698	COG2359	stage V sporulation protein S
FX981_03699	COG1692	metallophosphoesterase
FX981_03700	COG1418	mRNA catabolic process
FX981_03701	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FX981_03702	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FX981_03703	COG1546	Belongs to the CinA family
FX981_03703	COG1058	Belongs to the CinA family
FX981_03704	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FX981_03705	COG1426	Protein conserved in bacteria
FX981_03708	COG0300	oxidoreductase activity
FX981_03709	COG2409	Drug exporters of the RND superfamily
FX981_03709	COG1033	growth of symbiont in host cell
FX981_03711	COG0612	Peptidase, M16
FX981_03712	COG0612	Peptidase, M16
FX981_03713	COG2409	Drug exporters of the RND superfamily
FX981_03713	COG1033	growth of symbiont in host cell
FX981_03714	COG2814	Major facilitator Superfamily
FX981_03715	COG2188	Transcriptional regulator
FX981_03716	COG4980	gas vesicle protein
FX981_03716	COG1674	ftsk spoiiie
FX981_03718	COG0740	serine-type endopeptidase activity
FX981_03719	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FX981_03721	COG0527	aspartate kinase activity
FX981_03722	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FX981_03723	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FX981_03724	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FX981_03725	COG1873	PFAM PRC-barrel domain
FX981_03727	COG0612	Peptidase, M16
FX981_03728	COG0726	polysaccharide deacetylase
FX981_03729	COG1185	polyribonucleotide nucleotidyltransferase activity
FX981_03730	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FX981_03731	COG0196	riboflavin kinase activity
FX981_03732	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FX981_03733	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FX981_03734	COG1550	Protein conserved in bacteria
FX981_03735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FX981_03736	COG1358	cellular component organization or biogenesis
FX981_03737	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FX981_03738	COG0195	Participates in both transcription termination and antitermination
FX981_03739	COG0779	Required for maturation of 30S ribosomal subunits
FX981_03740	COG2890	protein-(glutamine-N5) methyltransferase activity
FX981_03748	COG1131	(ABC) transporter
FX981_03755	COG2176	DNA-directed DNA polymerase activity
FX981_03756	COG0442	prolyl-tRNA aminoacylation
FX981_03757	COG0750	zinc metalloprotease
FX981_03758	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FX981_03759	COG4589	Belongs to the CDS family
FX981_03760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FX981_03761	COG0233	cytoplasmic translational termination
FX981_03762	COG0528	UMP kinase activity
FX981_03763	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FX981_03766	COG1191	sigma factor activity
FX981_03768	COG1776	CheC inhibitor of MCP methylation
FX981_03769	COG0835	chemotaxis
FX981_03770	COG0643	Histidine kinase
FX981_03770	COG2198	Histidine kinase
FX981_03771	COG2201	protein-glutamate methylesterase activity
FX981_03772	COG0455	bacterial-type flagellum organization
FX981_03773	COG1419	protein localization to endoplasmic reticulum
FX981_03774	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FX981_03775	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FX981_03776	COG1684	flagellar biosynthetic protein fliR
FX981_03777	COG1987	bacterial-type flagellum assembly
FX981_03778	COG1338	Plays a role in the flagellum-specific transport system
FX981_03779	COG3190	flagellar
FX981_03780	COG2201	protein-glutamate methylesterase activity
FX981_03781	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FX981_03781	COG1776	CheC inhibitor of MCP methylation
FX981_03782	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FX981_03783	COG1580	Controls the rotational direction of flagella during chemotaxis
FX981_03784	COG1582	Flagellar protein (FlbD)
FX981_03785	COG4786	Flagellar basal body rod
FX981_03786	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FX981_03787	COG3144	bacterial-type flagellum assembly
FX981_03788	COG3334	PFAM MgtE intracellular
FX981_03789	COG2882	bacterial-type flagellum organization
FX981_03790	COG1157	protein secretion by the type III secretion system
FX981_03791	COG1317	bacterial-type flagellum organization
FX981_03792	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FX981_03793	COG1766	The M ring may be actively involved in energy transduction
FX981_03794	COG1677	Flagellar hook-basal body complex protein FliE
FX981_03795	COG1558	bacterial-type flagellum-dependent cell motility
FX981_03796	COG1815	bacterial-type flagellum-dependent cell motility
FX981_03797	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FX981_03798	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FX981_03799	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FX981_03800	COG4974	Belongs to the 'phage' integrase family
FX981_03801	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FX981_03802	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FX981_03803	COG0758	DNA mediated transformation
FX981_03804	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FX981_03805	COG0045	succinate-CoA ligase (ADP-forming) activity
FX981_03806	COG2257	FlhB HrpN YscU SpaS Family
FX981_03808	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FX981_03809	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FX981_03810	COG0335	large ribosomal subunit rRNA binding
FX981_03811	COG0336	Belongs to the RNA methyltransferase TrmD family
FX981_03812	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FX981_03814	COG1837	Belongs to the UPF0109 family
FX981_03815	COG0228	four-way junction DNA binding
FX981_03816	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FX981_03817	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FX981_03818	COG0552	protein localization to endoplasmic reticulum
FX981_03819	COG1196	nuclear chromosome segregation
FX981_03821	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FX981_03822	COG1028	Short-chain dehydrogenase reductase Sdr
FX981_03823	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FX981_03824	COG0416	fatty acid biosynthetic process
FX981_03825	COG1349	DNA-binding transcription factor activity
FX981_03826	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FX981_03827	COG1760	l-serine dehydratase
FX981_03828	COG1760	l-serine dehydratase
FX981_03829	COG1461	Dihydroxyacetone kinase
FX981_03830	COG1302	Protein conserved in bacteria
FX981_03831	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FX981_03832	COG1564	THIamine pyrophosphokinase
FX981_03833	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FX981_03834	COG1162	GTPase activity
FX981_03835	COG2815	serine threonine protein kinase
FX981_03835	COG0515	serine threonine protein kinase
FX981_03836	COG0631	protein serine/threonine phosphatase activity
FX981_03837	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FX981_03838	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FX981_03838	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FX981_03839	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FX981_03840	COG0242	peptide deformylase activity
FX981_03841	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FX981_03842	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FX981_03843	COG1758	RNA polymerase activity
FX981_03844	COG0194	GDP metabolic process
FX981_03845	COG2052	Domain of unknown function (DUF370)
FX981_03846	COG1561	YicC-like family, N-terminal region
FX981_03847	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FX981_03849	COG1648	precorrin-2 dehydrogenase activity
FX981_03850	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FX981_03851	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FX981_03852	COG0529	Catalyzes the synthesis of activated sulfate
FX981_03853	COG2046	Belongs to the sulfate adenylyltransferase family
FX981_03854	COG0306	phosphate transporter
FX981_03855	COG0175	sulfate reduction