locus-tag	class	description
Bsel_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Bsel_0002	COG0592	DNA-directed DNA polymerase activity
Bsel_0003	COG2501	S4 domain
Bsel_0006	COG0187	DNA topoisomerase II activity
Bsel_0007	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bsel_0014	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Bsel_0015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Bsel_0016	COG0444	Belongs to the ABC transporter superfamily
Bsel_0017	COG4608	Belongs to the ABC transporter superfamily
Bsel_0018	COG0747	negative chemotaxis
Bsel_0019	COG0601	transmembrane transport
Bsel_0020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bsel_0021	COG0590	tRNA wobble adenosine to inosine editing
Bsel_0023	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Bsel_0024	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Bsel_0025	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Bsel_0027	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Bsel_0033	COG1982	Orn Lys Arg decarboxylase major
Bsel_0034	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Bsel_0035	COG3870	Protein conserved in bacteria
Bsel_0036	COG0470	DNA polymerase III
Bsel_0037	COG1774	PSP1 C-terminal conserved region
Bsel_0039	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
Bsel_0040	COG2827	Endonuclease containing a URI domain
Bsel_0041	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Bsel_0042	COG2002	toxin-antitoxin pair type II binding
Bsel_0043	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bsel_0043	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bsel_0044	COG0084	hydrolase, TatD family'
Bsel_0045	COG3583	domain protein
Bsel_0045	COG3584	3D domain protein
Bsel_0046	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
Bsel_0047	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Bsel_0048	COG4466	Protein conserved in bacteria
Bsel_0049	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Bsel_0050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bsel_0051	COG2088	sporulation resulting in formation of a cellular spore
Bsel_0052	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Bsel_0053	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Bsel_0055	COG0193	aminoacyl-tRNA hydrolase activity
Bsel_0056	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Bsel_0057	COG2244	polysaccharide biosynthetic process
Bsel_0058	COG3956	TIGRFAM MazG family protein
Bsel_0059	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Bsel_0060	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Bsel_0061	COG1098	S1 RNA binding domain
Bsel_0064	COG0037	tRNA processing
Bsel_0067	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Bsel_0068	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Bsel_0070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Bsel_0071	COG0512	Glutamine amidotransferase of anthranilate synthase
Bsel_0072	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bsel_0073	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Bsel_0074	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Bsel_0076	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bsel_0077	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Bsel_0079	COG1285	pathogenesis
Bsel_0081	COG3880	PFAM UvrB UvrC protein
Bsel_0082	COG3869	Catalyzes the specific phosphorylation of arginine residues in
Bsel_0083	COG0542	response to heat
Bsel_0084	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Bsel_0085	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Bsel_0086	COG4956	integral membrane protein (PIN domain superfamily)
Bsel_0087	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Bsel_0089	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Bsel_0090	COG1045	serine acetyltransferase
Bsel_0091	COG0215	cysteine-tRNA ligase activity
Bsel_0093	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bsel_0094	COG3688	RNA-binding protein containing a PIN domain
Bsel_0096	COG1595	DNA-templated transcription, initiation
Bsel_0098	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Bsel_0099	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bsel_0100	COG0250	Participates in transcription elongation, termination and antitermination
Bsel_0101	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Bsel_0102	COG0081	regulation of translation
Bsel_0103	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Bsel_0104	COG0222	ribosome binding
Bsel_0105	COG2813	Specifically methylates the guanine in position
Bsel_0106	COG0085	RNA polymerase activity
Bsel_0107	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Bsel_0108	COG1358	cellular component organization or biogenesis
Bsel_0109	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Bsel_0110	COG0049	tRNA binding
Bsel_0111	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Bsel_0112	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Bsel_0114	COG0051	transcription antitermination factor activity, RNA binding
Bsel_0115	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Bsel_0116	COG0088	Forms part of the polypeptide exit tunnel
Bsel_0117	COG0089	rRNA binding
Bsel_0118	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Bsel_0119	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Bsel_0120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Bsel_0121	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Bsel_0122	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Bsel_0123	COG0255	Belongs to the universal ribosomal protein uL29 family
Bsel_0124	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Bsel_0125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Bsel_0126	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Bsel_0127	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Bsel_0129	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Bsel_0130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Bsel_0131	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Bsel_0133	COG1841	ribosomal large subunit assembly
Bsel_0135	COG0563	adenylate kinase activity
Bsel_0136	COG0024	Methionine aminopeptidase
Bsel_0137	COG2163	COG2163 Ribosomal protein L14E L6E L27E
Bsel_0138	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Bsel_0139	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Bsel_0140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Bsel_0141	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Bsel_0142	COG0202	RNA polymerase activity
Bsel_0143	COG0203	ribosomal protein L17
Bsel_0144	COG1122	ATPase activity
Bsel_0146	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Bsel_0147	COG0101	tRNA pseudouridine synthase activity
Bsel_0148	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Bsel_0149	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Bsel_0150	COG3344	reverse transcriptase
Bsel_0151	COG2268	Band 7 protein
Bsel_0152	COG1876	peptidase activity
Bsel_0153	COG1902	pentaerythritol trinitrate reductase activity
Bsel_0155	COG0415	Belongs to the DNA photolyase family
Bsel_0161	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Bsel_0162	COG1304	FMN binding
Bsel_0163	COG0549	Belongs to the carbamate kinase family
Bsel_0164	COG0385	Bile acid
Bsel_0165	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Bsel_0168	COG2113	Glycine betaine
Bsel_0169	COG1510	regulation of RNA biosynthetic process
Bsel_0173	COG2239	Acts as a magnesium transporter
Bsel_0178	COG0363	glucosamine-6-phosphate deaminase activity
Bsel_0181	COG3394	polysaccharide catabolic process
Bsel_0182	COG1486	melibiose metabolic process
Bsel_0183	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bsel_0184	COG1447	Phosphotransferase system cellobiose-specific component IIA
Bsel_0185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Bsel_0188	COG3876	Protein conserved in bacteria
Bsel_0190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Bsel_0192	COG1175	transmembrane transport
Bsel_0193	COG0395	ABC-type sugar transport system, permease component
Bsel_0194	COG1472	Belongs to the glycosyl hydrolase 3 family
Bsel_0195	COG1737	Transcriptional regulator
Bsel_0196	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Bsel_0202	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Bsel_0207	COG2801	Transposase and inactivated derivatives
Bsel_0212	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Bsel_0215	COG1595	DNA-templated transcription, initiation
Bsel_0222	COG2770	Histidine kinase
Bsel_0222	COG3437	response regulator, receiver
Bsel_0225	COG2205	protein histidine kinase activity
Bsel_0243	COG0577	efflux transmembrane transporter activity
Bsel_0244	COG1136	(ABC) transporter
Bsel_0246	COG1473	amidohydrolase
Bsel_0248	COG0590	tRNA wobble adenosine to inosine editing
Bsel_0255	COG2409	Drug exporters of the RND superfamily
Bsel_0255	COG1033	growth of symbiont in host cell
Bsel_0256	COG0596	Alpha beta hydrolase
Bsel_0257	COG0523	cobalamin synthesis protein
Bsel_0263	COG1115	amino acid carrier protein
Bsel_0269	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Bsel_0269	COG3976	FMN-binding domain protein
Bsel_0270	COG0667	Aldo Keto reductase
Bsel_0272	COG0745	RESPONSE REGULATOR receiver
Bsel_0273	COG5002	protein histidine kinase activity
Bsel_0274	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Bsel_0277	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Bsel_0279	COG0471	metal ion transport
Bsel_0280	COG0745	RESPONSE REGULATOR receiver
Bsel_0280	COG3706	GGDEF domain
Bsel_0282	COG0386	Belongs to the glutathione peroxidase family
Bsel_0284	COG1131	(ABC) transporter
Bsel_0285	COG3559	Exporter of polyketide antibiotics
Bsel_0290	COG1131	(ABC) transporter
Bsel_0291	COG2197	response regulator
Bsel_0292	COG4585	Histidine kinase
Bsel_0293	COG2197	response regulator
Bsel_0294	COG4585	Histidine kinase
Bsel_0297	COG0584	glycerophosphoryl diester phosphodiesterase
Bsel_0300	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bsel_0300	COG0596	Alpha beta hydrolase
Bsel_0301	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Bsel_0304	COG0716	FMN binding
Bsel_0305	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bsel_0306	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bsel_0309	COG2814	Major facilitator Superfamily
Bsel_0313	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Bsel_0317	COG5002	protein histidine kinase activity
Bsel_0318	COG0745	RESPONSE REGULATOR receiver
Bsel_0319	COG1595	DNA-templated transcription, initiation
Bsel_0321	COG1609	Transcriptional regulator
Bsel_0322	COG5578	integral membrane protein
Bsel_0323	COG1653	transport
Bsel_0327	COG0596	Alpha beta hydrolase
Bsel_0328	COG3706	GGDEF domain
Bsel_0328	COG0745	RESPONSE REGULATOR receiver
Bsel_0331	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Bsel_0332	COG4149	molybdate abc transporter
Bsel_0335	COG1653	transport
Bsel_0336	COG1175	transmembrane transport
Bsel_0337	COG0395	ABC-type sugar transport system, permease component
Bsel_0340	COG3940	Belongs to the glycosyl hydrolase 43 family
Bsel_0342	COG1069	ribulokinase activity
Bsel_0343	COG2160	L-arabinose isomerase activity
Bsel_0344	COG1609	Transcriptional regulator
Bsel_0345	COG0371	Dehydrogenase
Bsel_0348	COG0583	DNA-binding transcription factor activity
Bsel_0351	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Bsel_0354	COG4175	Glycine betaine
Bsel_0354	COG0517	IMP dehydrogenase activity
Bsel_0355	COG1510	regulation of RNA biosynthetic process
Bsel_0360	COG1132	(ABC) transporter
Bsel_0361	COG1132	(ABC) transporter
Bsel_0364	COG0667	Aldo Keto reductase
Bsel_0366	COG1115	amino acid carrier protein
Bsel_0367	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Bsel_0368	COG0489	protein tyrosine kinase activity
Bsel_0369	COG2194	sulfuric ester hydrolase activity
Bsel_0370	COG1595	DNA-templated transcription, initiation
Bsel_0371	COG5662	AntiSigma factor
Bsel_0372	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
Bsel_0373	COG4856	YbbR-like protein
Bsel_0374	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bsel_0376	COG1131	(ABC) transporter
Bsel_0378	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Bsel_0379	COG0346	lactoylglutathione lyase activity
Bsel_0382	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
Bsel_0386	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Bsel_0392	COG0295	cytidine deaminase activity
Bsel_0394	COG2409	Drug exporters of the RND superfamily
Bsel_0396	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bsel_0397	COG2746	aminoglycoside 3-N-acetyltransferase activity
Bsel_0398	COG2135	peptidase activity
Bsel_0402	COG1595	DNA-templated transcription, initiation
Bsel_0404	COG3344	reverse transcriptase
Bsel_0407	COG0456	acetyltransferase
Bsel_0409	COG0840	transmembrane signaling receptor activity
Bsel_0411	COG1704	LemA family
Bsel_0413	COG1653	transport
Bsel_0419	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Bsel_0420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Bsel_0421	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
Bsel_0424	COG0398	Pfam SNARE associated Golgi protein
Bsel_0427	COG0346	lactoylglutathione lyase activity
Bsel_0428	COG1846	Transcriptional regulator
Bsel_0429	COG0655	NAD(P)H dehydrogenase (quinone) activity
Bsel_0431	COG0501	Belongs to the peptidase M48B family
Bsel_0432	COG5002	protein histidine kinase activity
Bsel_0433	COG2204	response regulator
Bsel_0437	COG4989	oxidoreductase activity
Bsel_0440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bsel_0440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bsel_0442	COG1234	tRNA 3'-trailer cleavage
Bsel_0443	COG0745	RESPONSE REGULATOR receiver
Bsel_0443	COG3706	GGDEF domain
Bsel_0445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Bsel_0446	COG1175	transmembrane transport
Bsel_0447	COG0395	ABC-type sugar transport system, permease component
Bsel_0452	COG5578	integral membrane protein
Bsel_0456	COG5426	von Willebrand factor, type A
Bsel_0457	COG0800	Aldolase
Bsel_0459	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_0460	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
Bsel_0461	COG1272	protein, Hemolysin III
Bsel_0464	COG2860	membrane
Bsel_0465	COG0604	alcohol dehydrogenase
Bsel_0468	COG0398	Pfam SNARE associated Golgi protein
Bsel_0472	COG1131	(ABC) transporter
Bsel_0478	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bsel_0479	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Bsel_0480	COG0477	Major facilitator Superfamily
Bsel_0483	COG0626	cystathionine gamma-synthase activity
Bsel_0484	COG0626	cystathionine gamma-synthase activity
Bsel_0486	COG1410	methionine synthase
Bsel_0486	COG0646	methionine synthase
Bsel_0487	COG1227	inorganic diphosphatase activity
Bsel_0490	COG0765	amino acid transport
Bsel_0491	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bsel_0494	COG2239	Acts as a magnesium transporter
Bsel_0495	COG2239	Acts as a magnesium transporter
Bsel_0496	COG2202	Pas domain
Bsel_0496	COG1366	Belongs to the anti-sigma-factor antagonist family
Bsel_0498	COG0534	Mate efflux family protein
Bsel_0500	COG0589	response to stress
Bsel_0501	COG0659	secondary active sulfate transmembrane transporter activity
Bsel_0503	COG1278	Cold shock
Bsel_0506	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Bsel_0507	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Bsel_0508	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bsel_0511	COG3300	MHYT domain
Bsel_0511	COG5001	Diguanylate cyclase
Bsel_0512	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Bsel_0515	COG1595	DNA-templated transcription, initiation
Bsel_0517	COG3386	PFAM SMP-30 Gluconolaconase
Bsel_0519	COG3829	transcription factor binding
Bsel_0520	COG1012	belongs to the aldehyde dehydrogenase family
Bsel_0521	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bsel_0522	COG0506	proline dehydrogenase activity
Bsel_0524	COG3842	ATPase activity
Bsel_0526	COG1178	ABC-type Fe3 transport system permease component
Bsel_0527	COG0705	Rhomboid family
Bsel_0529	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Bsel_0529	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Bsel_0530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Bsel_0531	COG0864	Transcriptional regulator
Bsel_0532	COG2337	Toxic component of a toxin-antitoxin (TA) module
Bsel_0533	COG1366	Belongs to the anti-sigma-factor antagonist family
Bsel_0534	COG1366	Belongs to the anti-sigma-factor antagonist family
Bsel_0535	COG2172	sigma factor antagonist activity
Bsel_0536	COG2208	phosphoserine phosphatase activity
Bsel_0537	COG1366	Belongs to the anti-sigma-factor antagonist family
Bsel_0538	COG2172	sigma factor antagonist activity
Bsel_0539	COG1191	sigma factor activity
Bsel_0541	COG2183	response to ionizing radiation
Bsel_0542	COG3091	SprT-like family
Bsel_0543	COG1271	oxidase subunit
Bsel_0544	COG1294	oxidase, subunit
Bsel_0545	COG4988	ABC transporter
Bsel_0546	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Bsel_0547	COG0626	cystathionine gamma-synthase activity
Bsel_0548	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Bsel_0549	COG0802	atpase or kinase
Bsel_0550	COG1214	PFAM Peptidase M22, glycoprotease
Bsel_0551	COG0456	acetyltransferase
Bsel_0552	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Bsel_0553	COG0488	(ABC) transporter
Bsel_0555	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Bsel_0556	COG2814	Major facilitator Superfamily
Bsel_0559	COG2204	response regulator
Bsel_0560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Bsel_0563	COG0243	molybdopterin cofactor binding
Bsel_0566	COG1266	CAAX protease self-immunity
Bsel_0568	COG0459	protein refolding
Bsel_0569	COG2203	Gaf domain
Bsel_0569	COG5001	Diguanylate cyclase
Bsel_0569	COG4251	negative regulation of phosphorylation
Bsel_0569	COG3706	GGDEF domain
Bsel_0570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Bsel_0571	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bsel_0572	COG2508	Transcriptional regulator
Bsel_0573	COG0154	amidase activity
Bsel_0574	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Bsel_0576	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Bsel_0577	COG2080	2 iron, 2 sulfur cluster binding
Bsel_0578	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Bsel_0579	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Bsel_0580	COG0402	S-adenosylhomocysteine deaminase activity
Bsel_0582	COG3195	allantoin biosynthetic process
Bsel_0582	COG3648	Uricase
Bsel_0583	COG2351	hydroxyisourate hydrolase activity
Bsel_0585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Bsel_0586	COG0783	Belongs to the Dps family
Bsel_0588	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Bsel_0589	COG0640	Transcriptional regulator
Bsel_0591	COG0456	acetyltransferase
Bsel_0594	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bsel_0596	COG0415	Belongs to the DNA photolyase family
Bsel_0599	COG1063	alcohol dehydrogenase
Bsel_0600	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bsel_0601	COG0022	dehydrogenase e1 component
Bsel_0602	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bsel_0603	COG3284	Transcriptional regulator
Bsel_0604	COG3279	Response regulator of the LytR AlgR family
Bsel_0605	COG2972	Histidine kinase
Bsel_0605	COG0745	RESPONSE REGULATOR receiver
Bsel_0608	COG0784	Response regulator, receiver
Bsel_0609	COG4191	Histidine kinase
Bsel_0612	COG1027	Aspartate ammonia-lyase
Bsel_0613	COG2009	succinate dehydrogenase
Bsel_0614	COG1053	succinate dehydrogenase
Bsel_0615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Bsel_0616	COG1846	Transcriptional regulator
Bsel_0618	COG3706	GGDEF domain
Bsel_0618	COG0745	RESPONSE REGULATOR receiver
Bsel_0619	COG0745	RESPONSE REGULATOR receiver
Bsel_0620	COG5002	protein histidine kinase activity
Bsel_0625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Bsel_0627	COG1272	protein, Hemolysin III
Bsel_0628	COG2226	methyltransferase
Bsel_0634	COG3290	protein histidine kinase activity
Bsel_0634	COG0840	transmembrane signaling receptor activity
Bsel_0636	COG0437	4 iron, 4 sulfur cluster binding
Bsel_0638	COG1215	transferase activity, transferring glycosyl groups
Bsel_0639	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Bsel_0640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Bsel_0641	COG1827	regulation of RNA biosynthetic process
Bsel_0642	COG2133	pyrroloquinoline quinone binding
Bsel_0643	COG1454	alcohol dehydrogenase
Bsel_0647	COG1595	DNA-templated transcription, initiation
Bsel_0649	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bsel_0649	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bsel_0652	COG5002	protein histidine kinase activity
Bsel_0653	COG0745	RESPONSE REGULATOR receiver
Bsel_0654	COG3706	GGDEF domain
Bsel_0657	COG1366	Belongs to the anti-sigma-factor antagonist family
Bsel_0662	COG0784	Response regulator, receiver
Bsel_0662	COG3437	response regulator, receiver
Bsel_0664	COG0584	glycerophosphoryl diester phosphodiesterase
Bsel_0667	COG4988	ABC transporter
Bsel_0668	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Bsel_0669	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bsel_0671	COG0778	Nitroreductase
Bsel_0673	COG0590	tRNA wobble adenosine to inosine editing
Bsel_0675	COG0714	Associated with various cellular activities
Bsel_0676	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
Bsel_0677	COG1305	Transglutaminase-like
Bsel_0678	COG0519	Catalyzes the synthesis of GMP from XMP
Bsel_0678	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Bsel_0679	COG2252	PERMEase
Bsel_0681	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bsel_0685	COG0542	response to heat
Bsel_0688	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Bsel_0689	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Bsel_0690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Bsel_0691	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Bsel_0692	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bsel_0693	COG0047	phosphoribosylformylglycinamidine synthase activity
Bsel_0694	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Bsel_0695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Bsel_0697	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Bsel_0699	COG0151	Belongs to the GarS family
Bsel_0701	COG0516	GMP reductase activity
Bsel_0701	COG0517	IMP dehydrogenase activity
Bsel_0706	COG3118	belongs to the thioredoxin family
Bsel_0706	COG0492	ferredoxin-NADP+ reductase activity
Bsel_0707	COG0405	Gamma-glutamyltransferase
Bsel_0708	COG1181	Belongs to the D-alanine--D-alanine ligase family
Bsel_0710	COG3275	phosphorelay sensor kinase activity
Bsel_0711	COG3279	Response regulator of the LytR AlgR family
Bsel_0712	COG1966	Carbon starvation protein
Bsel_0715	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Bsel_0716	COG1470	cell adhesion involved in biofilm formation
Bsel_0717	COG4496	protein, YerC YecD
Bsel_0719	COG4120	Belongs to the binding-protein-dependent transport system permease family
Bsel_0721	COG0450	alkyl hydroperoxide reductase
Bsel_0724	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bsel_0726	COG0523	cobalamin synthesis protein
Bsel_0728	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Bsel_0730	COG2124	cytochrome p450
Bsel_0734	COG0494	nUDIX hydrolase
Bsel_0736	COG0840	transmembrane signaling receptor activity
Bsel_0737	COG5001	Diguanylate cyclase
Bsel_0737	COG3300	MHYT domain
Bsel_0738	COG5001	Diguanylate cyclase
Bsel_0738	COG5002	protein histidine kinase activity
Bsel_0738	COG3447	MASE1 domain protein
Bsel_0739	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Bsel_0740	COG0210	DNA helicase
Bsel_0741	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Bsel_0743	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Bsel_0744	COG0154	amidase activity
Bsel_0745	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Bsel_0747	COG1597	lipid kinase activity
Bsel_0751	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Bsel_0755	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Bsel_0756	COG1233	COG1233 Phytoene dehydrogenase and related
Bsel_0757	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bsel_0760	COG1002	Type II restriction enzyme, methylase subunits
Bsel_0761	COG1061	Type III restriction enzyme res subunit
Bsel_0762	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Bsel_0790	COG4695	Portal protein
Bsel_0791	COG0740	serine-type endopeptidase activity
Bsel_0806	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bsel_0806	COG3409	Peptidoglycan-binding domain 1 protein
Bsel_0811	COG0747	negative chemotaxis
Bsel_0813	COG0737	Belongs to the 5'-nucleotidase family
Bsel_0814	COG0561	phosphatase activity
Bsel_0815	COG0840	transmembrane signaling receptor activity
Bsel_0824	COG2801	Transposase and inactivated derivatives
Bsel_0836	COG2801	Transposase and inactivated derivatives
Bsel_0841	COG3436	PFAM IS66 Orf2 family protein
Bsel_0850	COG1404	Belongs to the peptidase S8 family
Bsel_0851	COG3883	PFAM NLP P60 protein
Bsel_0851	COG0791	NLP P60 protein
Bsel_0854	COG2855	membrane
Bsel_0860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Bsel_0865	COG0124	histidyl-tRNA synthetase
Bsel_0871	COG3279	Response regulator of the LytR AlgR family
Bsel_0872	COG2972	Histidine kinase
Bsel_0872	COG0745	RESPONSE REGULATOR receiver
Bsel_0876	COG0840	transmembrane signaling receptor activity
Bsel_0878	COG3279	Response regulator of the LytR AlgR family
Bsel_0880	COG5001	Diguanylate cyclase
Bsel_0880	COG3300	MHYT domain
Bsel_0881	COG0840	transmembrane signaling receptor activity
Bsel_0884	COG3279	Response regulator of the LytR AlgR family
Bsel_0885	COG2340	Cysteine-rich secretory protein family
Bsel_0891	COG1215	transferase activity, transferring glycosyl groups
Bsel_0893	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bsel_0896	COG3409	Peptidoglycan-binding domain 1 protein
Bsel_0896	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bsel_0898	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Bsel_0899	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Bsel_0901	COG2508	Transcriptional regulator
Bsel_0902	COG3711	transcriptional antiterminator
Bsel_0902	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bsel_0903	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bsel_0905	COG3037	sugar-specific permease SgaT UlaA
Bsel_0906	COG0561	phosphatase activity
Bsel_0907	COG1609	Transcriptional regulator
Bsel_0908	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Bsel_0909	COG1869	D-ribose catabolic process
Bsel_0910	COG1129	ABC transporter
Bsel_0911	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bsel_0912	COG1879	ABC-type sugar transport system periplasmic component
Bsel_0924	COG0579	oxidoreductase
Bsel_0925	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bsel_0928	COG3046	protein related to deoxyribodipyrimidine photolyase
Bsel_0929	COG1349	DNA-binding transcription factor activity
Bsel_0930	COG1105	Belongs to the carbohydrate kinase PfkB family
Bsel_0931	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bsel_0931	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bsel_0931	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
Bsel_0932	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Bsel_0935	COG1131	(ABC) transporter
Bsel_0936	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Bsel_0937	COG2376	Dihydroxyacetone kinase
Bsel_0938	COG1461	Dihydroxyacetone kinase
Bsel_0939	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
Bsel_0941	COG2376	Dihydroxyacetone kinase
Bsel_0943	COG2340	Cysteine-rich secretory protein family
Bsel_0955	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_0956	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bsel_0958	COG3290	protein histidine kinase activity
Bsel_0958	COG3829	transcription factor binding
Bsel_0959	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Bsel_0960	COG4608	Belongs to the ABC transporter superfamily
Bsel_0961	COG0444	Belongs to the ABC transporter superfamily
Bsel_0962	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bsel_0964	COG0747	negative chemotaxis
Bsel_0966	COG0701	Predicted permease
Bsel_0970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Bsel_0970	COG0574	Belongs to the PEP-utilizing enzyme family
Bsel_0971	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Bsel_0975	COG1620	l-lactate permease
Bsel_0977	COG0840	transmembrane signaling receptor activity
Bsel_0979	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Bsel_0980	COG3458	cephalosporin-C deacetylase activity
Bsel_0981	COG2318	DinB family
Bsel_0983	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Bsel_0985	COG1984	allophanate hydrolase subunit 2
Bsel_0987	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Bsel_0989	COG1666	GTP binding
Bsel_0991	COG0737	Belongs to the 5'-nucleotidase family
Bsel_0993	COG1523	belongs to the glycosyl hydrolase 13 family
Bsel_0997	COG0326	Molecular chaperone. Has ATPase activity
Bsel_1001	COG1363	Peptidase, m42
Bsel_1004	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Bsel_1005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Bsel_1007	COG5002	protein histidine kinase activity
Bsel_1011	COG0717	Belongs to the dCTP deaminase family
Bsel_1012	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bsel_1016	COG1316	TRANSCRIPTIONal
Bsel_1017	COG1739	Uncharacterized protein family UPF0029
Bsel_1020	COG1307	EDD domain protein, DegV family
Bsel_1021	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
Bsel_1025	COG2747	anti-sigma28 factor FlgM
Bsel_1027	COG4786	Flagellar basal body rod
Bsel_1027	COG1256	bacterial-type flagellum assembly
Bsel_1028	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bsel_1030	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
Bsel_1031	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Bsel_1033	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Bsel_1039	COG2807	transmembrane transport
Bsel_1042	COG0352	thiamine-phosphate diphosphorylase activity
Bsel_1043	COG0351	phosphomethylpyrimidine kinase
Bsel_1044	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Bsel_1045	COG1278	Cold shock
Bsel_1048	COG5001	Diguanylate cyclase
Bsel_1048	COG3300	MHYT domain
Bsel_1050	COG1295	ribonuclease BN
Bsel_1051	COG2267	carboxylic ester hydrolase activity
Bsel_1055	COG0702	epimerase
Bsel_1056	COG3437	response regulator, receiver
Bsel_1057	COG0840	transmembrane signaling receptor activity
Bsel_1059	COG2199	diguanylate cyclase activity
Bsel_1060	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Bsel_1061	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Bsel_1063	COG1334	flagellar protein FlaG
Bsel_1064	COG1516	flagellar protein fliS
Bsel_1067	COG0737	Belongs to the 5'-nucleotidase family
Bsel_1072	COG1278	Cold shock
Bsel_1073	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Bsel_1074	COG1263	PTS System
Bsel_1074	COG2190	(PTS) system
Bsel_1074	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bsel_1075	COG3711	transcriptional antiterminator
Bsel_1076	COG0653	protein targeting
Bsel_1078	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bsel_1080	COG2884	Cell division ATP-binding protein ftsE
Bsel_1081	COG2177	Part of the ABC transporter FtsEX involved in
Bsel_1082	COG0741	lytic transglycosylase activity
Bsel_1082	COG0739	heme binding
Bsel_1082	COG1196	nuclear chromosome segregation
Bsel_1083	COG3409	Peptidoglycan-binding domain 1 protein
Bsel_1083	COG0793	Belongs to the peptidase S41A family
Bsel_1084	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bsel_1085	COG0556	nucleotide-excision repair
Bsel_1086	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Bsel_1087	COG3595	metallopeptidase activity
Bsel_1089	COG1950	PFAM Membrane protein of
Bsel_1090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Bsel_1091	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Bsel_1092	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
Bsel_1094	COG0110	maltose O-acetyltransferase activity
Bsel_1095	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Bsel_1096	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Bsel_1097	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Bsel_1098	COG0131	Imidazoleglycerol-phosphate dehydratase
Bsel_1099	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Bsel_1100	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Bsel_1101	COG0107	imidazoleglycerol-phosphate synthase activity
Bsel_1102	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Bsel_1102	COG0140	phosphoribosyl-ATP diphosphatase activity
Bsel_1103	COG1233	COG1233 Phytoene dehydrogenase and related
Bsel_1105	COG0492	ferredoxin-NADP+ reductase activity
Bsel_1106	COG1660	Displays ATPase and GTPase activities
Bsel_1107	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Bsel_1108	COG1481	regulation of sporulation
Bsel_1109	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bsel_1110	COG0740	serine-type endopeptidase activity
Bsel_1111	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Bsel_1112	COG2390	Transcriptional regulator
Bsel_1113	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bsel_1114	COG0126	phosphoglycerate kinase activity
Bsel_1115	COG0149	triose-phosphate isomerase activity
Bsel_1116	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Bsel_1117	COG0148	phosphopyruvate hydratase activity
Bsel_1118	COG0583	DNA-binding transcription factor activity
Bsel_1121	COG1177	transmembrane transport
Bsel_1122	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bsel_1123	COG0673	inositol 2-dehydrogenase activity
Bsel_1124	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Bsel_1126	COG1647	Serine aminopeptidase, S33
Bsel_1127	COG0557	exoribonuclease II activity
Bsel_1128	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Bsel_1131	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Bsel_1132	COG0129	dihydroxy-acid dehydratase activity
Bsel_1136	COG5002	protein histidine kinase activity
Bsel_1137	COG0745	RESPONSE REGULATOR receiver
Bsel_1139	COG0201	protein transport
Bsel_1140	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bsel_1140	COG1024	Enoyl-CoA hydratase
Bsel_1141	COG0183	Belongs to the thiolase family
Bsel_1142	COG1960	acyl-CoA dehydrogenase activity
Bsel_1145	COG0509	glycine decarboxylation via glycine cleavage system
Bsel_1147	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Bsel_1148	COG2011	ABC-type metal ion transport system permease component
Bsel_1149	COG1464	Belongs to the NlpA lipoprotein family
Bsel_1152	COG5001	Diguanylate cyclase
Bsel_1153	COG0396	ATPase activity
Bsel_1154	COG0719	Fe-S assembly protein
Bsel_1155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Bsel_1156	COG0822	iron-sulfur transferase activity
Bsel_1157	COG0719	Fe-S assembly protein
Bsel_1158	COG1801	Protein of unknown function DUF72
Bsel_1159	COG0730	response to heat
Bsel_1160	COG0737	Belongs to the 5'-nucleotidase family
Bsel_1162	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Bsel_1164	COG1757	Na H antiporter
Bsel_1168	COG1494	fructose-1,6-bisphosphatase
Bsel_1169	COG2445	Protein of unknown function DUF86
Bsel_1171	COG0647	UMP catabolic process
Bsel_1172	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Bsel_1173	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Bsel_1174	COG4837	Protein of unknown function (DUF1462)
Bsel_1175	COG1252	NADH dehydrogenase
Bsel_1176	COG4844	belongs to the
Bsel_1178	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Bsel_1179	COG0316	Belongs to the HesB IscA family
Bsel_1180	COG0492	ferredoxin-NADP+ reductase activity
Bsel_1184	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
Bsel_1186	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Bsel_1187	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Bsel_1192	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Bsel_1193	COG0644	oxidoreductase
Bsel_1195	COG1522	sequence-specific DNA binding
Bsel_1196	COG0436	Aminotransferase
Bsel_1197	COG1098	S1 RNA binding domain
Bsel_1198	COG1979	alcohol dehydrogenase
Bsel_1199	COG0166	Belongs to the GPI family
Bsel_1201	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Bsel_1205	COG0733	neurotransmitter:sodium symporter activity
Bsel_1208	COG2210	Belongs to the sulfur carrier protein TusA family
Bsel_1209	COG1937	Protein conserved in bacteria
Bsel_1211	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bsel_1216	COG0589	response to stress
Bsel_1219	COG0437	4 iron, 4 sulfur cluster binding
Bsel_1222	COG0746	molybdenum cofactor guanylyltransferase activity
Bsel_1223	COG0303	'Molybdopterin
Bsel_1224	COG0303	'Molybdopterin
Bsel_1225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Bsel_1226	COG0494	nUDIX hydrolase
Bsel_1227	COG1506	peptidase
Bsel_1229	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Bsel_1230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Bsel_1231	COG2267	carboxylic ester hydrolase activity
Bsel_1233	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
Bsel_1234	COG1242	4 iron, 4 sulfur cluster binding
Bsel_1235	COG0495	leucyl-tRNA aminoacylation
Bsel_1236	COG2081	HI0933 family
Bsel_1238	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bsel_1239	COG0432	Pfam Uncharacterised protein family UPF0047
Bsel_1240	COG0772	Belongs to the SEDS family
Bsel_1241	COG0772	Belongs to the SEDS family
Bsel_1242	COG1187	pseudouridine synthase activity
Bsel_1243	COG1349	DNA-binding transcription factor activity
Bsel_1245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Bsel_1246	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Bsel_1249	COG0058	SHG alpha-glucan phosphorylase activity
Bsel_1250	COG0297	glycogen (starch) synthase activity
Bsel_1251	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Bsel_1252	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Bsel_1253	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Bsel_1254	COG1523	belongs to the glycosyl hydrolase 13 family
Bsel_1255	COG0510	thiamine kinase activity
Bsel_1256	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Bsel_1257	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bsel_1259	COG1363	Peptidase, m42
Bsel_1263	COG4848	Belongs to the UPF0354 family
Bsel_1267	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Bsel_1271	COG3118	belongs to the thioredoxin family
Bsel_1272	COG0849	cell division
Bsel_1273	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Bsel_1273	COG1605	Chorismate mutase
Bsel_1277	COG0454	-acetyltransferase
Bsel_1278	COG0517	IMP dehydrogenase activity
Bsel_1279	COG0123	including yeast histone deacetylase and acetoin utilization protein
Bsel_1282	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Bsel_1285	COG1131	(ABC) transporter
Bsel_1286	COG1309	transcriptional regulator
Bsel_1290	COG0628	permease
Bsel_1292	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Bsel_1293	COG1140	nitrate reductase beta subunit
Bsel_1294	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Bsel_1295	COG2181	nitrate reductase activity
Bsel_1296	COG2223	nitrite transmembrane transporter activity
Bsel_1297	COG2223	nitrite transmembrane transporter activity
Bsel_1299	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Bsel_1301	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bsel_1302	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bsel_1303	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Bsel_1305	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
Bsel_1309	COG1138	Cytochrome C-type biogenesis protein
Bsel_1313	COG4555	ABC transporter
Bsel_1315	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bsel_1318	COG0708	Exodeoxyribonuclease III
Bsel_1319	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bsel_1322	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Bsel_1323	COG2203	Gaf domain
Bsel_1323	COG2199	diguanylate cyclase activity
Bsel_1324	COG1956	GAF domain-containing protein
Bsel_1325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bsel_1326	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
Bsel_1328	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Bsel_1329	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Bsel_1330	COG0616	signal peptide processing
Bsel_1331	COG1714	RDD family
Bsel_1332	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Bsel_1333	COG0827	DNA restriction-modification system
Bsel_1334	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Bsel_1336	COG0589	response to stress
Bsel_1337	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_1338	COG0006	proline dipeptidase activity
Bsel_1341	COG4109	DRTGG domain
Bsel_1343	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
Bsel_1344	COG0587	DNA-directed DNA polymerase activity
Bsel_1345	COG0281	malic enzyme
Bsel_1347	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Bsel_1348	COG0825	malonyl-CoA metabolic process
Bsel_1349	COG0205	6-phosphofructokinase activity
Bsel_1351	COG3030	protein affecting phage T7 exclusion by the F plasmid
Bsel_1352	COG2707	UPF0756 membrane protein
Bsel_1353	COG0372	Belongs to the citrate synthase family
Bsel_1354	COG0538	isocitrate dehydrogenase activity
Bsel_1355	COG0039	L-malate dehydrogenase activity
Bsel_1357	COG0745	RESPONSE REGULATOR receiver
Bsel_1358	COG5002	protein histidine kinase activity
Bsel_1359	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bsel_1359	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bsel_1360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Bsel_1361	COG0237	dephospho-CoA kinase activity
Bsel_1362	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Bsel_1364	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Bsel_1365	COG3611	Membrane attachment protein
Bsel_1366	COG1484	DNA-dependent DNA replication
Bsel_1367	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Bsel_1368	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Bsel_1369	COG1716	ATPase activity
Bsel_1369	COG5001	Diguanylate cyclase
Bsel_1370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Bsel_1371	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Bsel_1372	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Bsel_1377	COG1363	Peptidase, m42
Bsel_1379	COG2113	Glycine betaine
Bsel_1380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Bsel_1381	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Bsel_1382	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bsel_1382	COG0072	phenylalanine-tRNA ligase activity
Bsel_1385	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
Bsel_1387	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Bsel_1387	COG1796	DNA polymerase
Bsel_1388	COG1193	negative regulation of DNA recombination
Bsel_1389	COG3766	membrane
Bsel_1391	COG0318	PFAM AMP-dependent synthetase and ligase
Bsel_1392	COG0318	PFAM AMP-dependent synthetase and ligase
Bsel_1393	COG1309	transcriptional regulator
Bsel_1394	COG1024	Enoyl-CoA hydratase
Bsel_1395	COG2086	electron transfer activity
Bsel_1396	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Bsel_1397	COG3118	belongs to the thioredoxin family
Bsel_1398	COG0322	excinuclease ABC activity
Bsel_1400	COG1719	4-vinyl reductase, 4VR
Bsel_1401	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Bsel_1402	COG2009	succinate dehydrogenase
Bsel_1403	COG1053	succinate dehydrogenase
Bsel_1404	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Bsel_1406	COG3711	transcriptional antiterminator
Bsel_1407	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Bsel_1408	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Bsel_1409	COG1846	Transcriptional regulator
Bsel_1410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Bsel_1411	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Bsel_1412	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Bsel_1413	COG0622	Phosphoesterase
Bsel_1415	COG0544	peptidyl-prolyl cis-trans isomerase activity
Bsel_1416	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Bsel_1418	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Bsel_1419	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Bsel_1420	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bsel_1421	COG0181	hydroxymethylbilane synthase activity
Bsel_1423	COG0113	porphobilinogen synthase activity
Bsel_1424	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Bsel_1431	COG4585	Histidine kinase
Bsel_1432	COG2197	response regulator
Bsel_1435	COG0285	dihydrofolate synthase activity
Bsel_1436	COG3706	GGDEF domain
Bsel_1439	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bsel_1441	COG1459	type II secretion system
Bsel_1442	COG4969	Belongs to the N-Me-Phe pilin family
Bsel_1444	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
Bsel_1449	COG1027	Aspartate ammonia-lyase
Bsel_1450	COG0424	maF-like protein
Bsel_1451	COG2003	Belongs to the UPF0758 family
Bsel_1452	COG1077	Cell shape determining protein MreB Mrl
Bsel_1453	COG1792	Involved in formation and maintenance of cell shape
Bsel_1454	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Bsel_1455	COG0850	regulation of cytokinetic process
Bsel_1456	COG2894	cell division
Bsel_1457	COG1653	transport
Bsel_1458	COG1609	Transcriptional regulator
Bsel_1461	COG1530	ribonuclease E activity
Bsel_1462	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Bsel_1463	COG2868	ribosomal protein
Bsel_1465	COG1234	tRNA 3'-trailer cleavage
Bsel_1467	COG0573	inorganic phosphate transmembrane transporter activity
Bsel_1468	COG0581	inorganic phosphate transmembrane transporter activity
Bsel_1469	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Bsel_1470	COG0704	Plays a role in the regulation of phosphate uptake
Bsel_1474	COG0840	transmembrane signaling receptor activity
Bsel_1474	COG3290	protein histidine kinase activity
Bsel_1475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bsel_1476	COG0243	molybdopterin cofactor binding
Bsel_1477	COG0437	4 iron, 4 sulfur cluster binding
Bsel_1481	COG0686	Belongs to the AlaDH PNT family
Bsel_1484	COG5001	Diguanylate cyclase
Bsel_1484	COG3300	MHYT domain
Bsel_1485	COG0745	RESPONSE REGULATOR receiver
Bsel_1486	COG5002	protein histidine kinase activity
Bsel_1489	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Bsel_1491	COG1309	transcriptional regulator
Bsel_1492	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bsel_1493	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Bsel_1496	COG2154	pterin-4-alpha-carbinolamine dehydratase
Bsel_1497	COG3300	MHYT domain
Bsel_1497	COG5001	Diguanylate cyclase
Bsel_1498	COG2249	NAD(P)H dehydrogenase (quinone) activity
Bsel_1501	COG1509	lysine 2,3-aminomutase activity
Bsel_1505	COG0534	Mate efflux family protein
Bsel_1506	COG0840	transmembrane signaling receptor activity
Bsel_1508	COG1175	transmembrane transport
Bsel_1509	COG3833	ABC-type maltose transport systems, permease component
Bsel_1511	COG0628	permease
Bsel_1512	COG0425	Belongs to the sulfur carrier protein TusA family
Bsel_1512	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bsel_1515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Bsel_1518	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
Bsel_1521	COG0561	phosphatase activity
Bsel_1522	COG3336	cytochrome c oxidase
Bsel_1523	COG1999	signal sequence binding
Bsel_1525	COG0314	molybdopterin synthase activity
Bsel_1526	COG1763	Mo-molybdopterin cofactor biosynthetic process
Bsel_1527	COG0303	'Molybdopterin
Bsel_1528	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bsel_1529	COG4841	protein insertion into membrane
Bsel_1530	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bsel_1534	COG1744	ABC transporter substrate-binding protein PnrA-like
Bsel_1536	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Bsel_1537	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Bsel_1539	COG1316	TRANSCRIPTIONal
Bsel_1540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bsel_1541	COG0180	Tryptophanyl-tRNA synthetase
Bsel_1543	COG1418	mRNA catabolic process
Bsel_1545	COG0456	acetyltransferase
Bsel_1546	COG1393	Belongs to the ArsC family
Bsel_1547	COG4862	establishment of competence for transformation
Bsel_1549	COG1164	Oligoendopeptidase f
Bsel_1551	COG2346	COG2346, Truncated hemoglobins
Bsel_1552	COG1196	nuclear chromosome segregation
Bsel_1552	COG0739	heme binding
Bsel_1552	COG0741	lytic transglycosylase activity
Bsel_1554	COG2357	RelA SpoT domain protein
Bsel_1555	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Bsel_1556	COG0564	pseudouridine synthase activity
Bsel_1562	COG0840	transmembrane signaling receptor activity
Bsel_1567	COG0493	'glutamate synthase
Bsel_1568	COG0840	transmembrane signaling receptor activity
Bsel_1569	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Bsel_1570	COG2224	Isocitrate lyase
Bsel_1571	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bsel_1572	COG1595	DNA-templated transcription, initiation
Bsel_1577	COG0656	L-ascorbic acid biosynthetic process
Bsel_1579	COG2151	metal-sulfur cluster biosynthetic enzyme
Bsel_1581	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Bsel_1582	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Bsel_1583	COG2153	protein acetylation
Bsel_1584	COG1854	S-ribosylhomocysteine lyase activity
Bsel_1585	COG0778	Nitroreductase
Bsel_1587	COG1136	(ABC) transporter
Bsel_1588	COG0569	domain protein
Bsel_1590	COG0668	transmembrane transport
Bsel_1592	COG2199	diguanylate cyclase activity
Bsel_1592	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Bsel_1593	COG2171	N-acyltransferase activity
Bsel_1594	COG1473	amidohydrolase
Bsel_1595	COG0668	transmembrane transport
Bsel_1596	COG0569	domain protein
Bsel_1597	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bsel_1599	COG0242	peptide deformylase activity
Bsel_1603	COG0022	dehydrogenase e1 component
Bsel_1604	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bsel_1610	COG1982	Orn Lys Arg decarboxylase major
Bsel_1611	COG4476	Belongs to the UPF0223 family
Bsel_1612	COG4493	Belongs to the UPF0637 family
Bsel_1614	COG0483	inositol monophosphate 1-phosphatase activity
Bsel_1617	COG4896	Protein conserved in bacteria
Bsel_1619	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Bsel_1620	COG4838	Belongs to the UPF0358 family
Bsel_1621	COG0783	Belongs to the Dps family
Bsel_1631	COG2340	Cysteine-rich secretory protein family
Bsel_1632	COG3679	Belongs to the UPF0342 family
Bsel_1633	COG4471	UPF0298 protein
Bsel_1634	COG0742	ribosomal rna small subunit methyltransferase
Bsel_1635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Bsel_1636	COG3480	Lon protease (S16) C-terminal proteolytic domain
Bsel_1637	COG1323	Belongs to the UPF0348 family
Bsel_1638	COG1399	metal-binding, possibly nucleic acid-binding protein
Bsel_1639	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Bsel_1641	COG0454	-acetyltransferase
Bsel_1642	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Bsel_1644	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
Bsel_1646	COG2001	Belongs to the MraZ family
Bsel_1647	COG0275	rRNA processing
Bsel_1650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Bsel_1651	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bsel_1652	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Bsel_1653	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Bsel_1654	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Bsel_1655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Bsel_1656	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Bsel_1657	COG3879	Bacterial protein of unknown function (DUF881)
Bsel_1659	COG3856	small basic protein
Bsel_1660	COG0849	cell division
Bsel_1661	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Bsel_1662	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Bsel_1663	COG1799	cell septum assembly
Bsel_1664	COG0762	integral membrane protein
Bsel_1666	COG3599	regulation of cell shape
Bsel_1667	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Bsel_1668	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Bsel_1669	COG0564	pseudouridine synthase activity
Bsel_1671	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Bsel_1674	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Bsel_1676	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Bsel_1677	COG0543	2 iron, 2 sulfur cluster binding
Bsel_1678	COG0167	dihydroorotate dehydrogenase activity
Bsel_1679	COG0284	orotidine-5'-phosphate decarboxylase activity
Bsel_1680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Bsel_1681	COG3344	reverse transcriptase
Bsel_1683	COG1132	(ABC) transporter
Bsel_1684	COG1132	(ABC) transporter
Bsel_1686	COG1561	YicC-like family, N-terminal region
Bsel_1687	COG2052	Domain of unknown function (DUF370)
Bsel_1688	COG0194	GDP metabolic process
Bsel_1689	COG1758	RNA polymerase activity
Bsel_1690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Bsel_1691	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Bsel_1692	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Bsel_1693	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Bsel_1693	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Bsel_1694	COG0631	protein serine/threonine phosphatase activity
Bsel_1695	COG0515	serine threonine protein kinase
Bsel_1695	COG2815	serine threonine protein kinase
Bsel_1696	COG1162	GTPase activity
Bsel_1697	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Bsel_1698	COG3859	Proton-coupled thiamine transporter YuaJ
Bsel_1700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Bsel_1701	COG1302	Protein conserved in bacteria
Bsel_1702	COG1461	Dihydroxyacetone kinase
Bsel_1703	COG1307	EDD domain protein, DegV family
Bsel_1704	COG1760	l-serine dehydratase
Bsel_1705	COG1760	l-serine dehydratase
Bsel_1706	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Bsel_1707	COG1349	DNA-binding transcription factor activity
Bsel_1708	COG0416	fatty acid biosynthetic process
Bsel_1709	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Bsel_1710	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_1711	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Bsel_1712	COG0571	ribonuclease III activity
Bsel_1714	COG4840	Belongs to the UPF0435 family
Bsel_1715	COG1196	nuclear chromosome segregation
Bsel_1716	COG0552	protein localization to endoplasmic reticulum
Bsel_1717	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
Bsel_1718	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Bsel_1719	COG0228	four-way junction DNA binding
Bsel_1720	COG1837	Belongs to the UPF0109 family
Bsel_1722	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Bsel_1724	COG0335	large ribosomal subunit rRNA binding
Bsel_1727	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Bsel_1729	COG2257	FlhB HrpN YscU SpaS Family
Bsel_1730	COG0045	succinate-CoA ligase (ADP-forming) activity
Bsel_1731	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Bsel_1732	COG0758	DNA mediated transformation
Bsel_1733	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Bsel_1734	COG4974	Belongs to the 'phage' integrase family
Bsel_1735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Bsel_1737	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
Bsel_1738	COG1815	bacterial-type flagellum-dependent cell motility
Bsel_1739	COG1558	bacterial-type flagellum-dependent cell motility
Bsel_1740	COG1677	Flagellar hook-basal body complex protein FliE
Bsel_1741	COG1766	The M ring may be actively involved in energy transduction
Bsel_1742	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bsel_1743	COG1317	bacterial-type flagellum organization
Bsel_1744	COG1157	protein secretion by the type III secretion system
Bsel_1748	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Bsel_1751	COG1582	Flagellar protein (FlbD)
Bsel_1753	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bsel_1754	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Bsel_1754	COG1776	CheC inhibitor of MCP methylation
Bsel_1755	COG2201	protein-glutamate methylesterase activity
Bsel_1756	COG3190	flagellar
Bsel_1757	COG1338	Plays a role in the flagellum-specific transport system
Bsel_1758	COG1987	bacterial-type flagellum assembly
Bsel_1759	COG1684	flagellar biosynthetic protein fliR
Bsel_1760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bsel_1761	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Bsel_1763	COG0455	bacterial-type flagellum organization
Bsel_1764	COG2201	protein-glutamate methylesterase activity
Bsel_1765	COG2198	Histidine kinase
Bsel_1765	COG0643	Histidine kinase
Bsel_1766	COG0835	chemotaxis
Bsel_1767	COG1776	CheC inhibitor of MCP methylation
Bsel_1768	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Bsel_1770	COG1191	sigma factor activity
Bsel_1774	COG0052	Belongs to the universal ribosomal protein uS2 family
Bsel_1775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Bsel_1776	COG0528	UMP kinase activity
Bsel_1777	COG0233	cytoplasmic translational termination
Bsel_1778	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Bsel_1779	COG4589	Belongs to the CDS family
Bsel_1780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Bsel_1781	COG0750	zinc metalloprotease
Bsel_1782	COG0442	prolyl-tRNA aminoacylation
Bsel_1783	COG2176	DNA-directed DNA polymerase activity
Bsel_1784	COG0779	Required for maturation of 30S ribosomal subunits
Bsel_1785	COG0195	Participates in both transcription termination and antitermination
Bsel_1786	COG2740	Nucleic-acid-binding protein implicated in transcription termination
Bsel_1788	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Bsel_1789	COG1550	Protein conserved in bacteria
Bsel_1790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Bsel_1791	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Bsel_1792	COG0196	riboflavin kinase activity
Bsel_1793	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Bsel_1794	COG1185	polyribonucleotide nucleotidyltransferase activity
Bsel_1795	COG0612	Peptidase, M16
Bsel_1796	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Bsel_1797	COG0527	aspartate kinase activity
Bsel_1799	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Bsel_1800	COG3344	reverse transcriptase
Bsel_1801	COG1674	ftsk spoiiie
Bsel_1802	COG2188	Transcriptional regulator
Bsel_1803	COG0612	Peptidase, M16
Bsel_1804	COG0612	Peptidase, M16
Bsel_1805	COG0300	oxidoreductase activity
Bsel_1807	COG1426	Protein conserved in bacteria
Bsel_1808	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Bsel_1809	COG1058	Belongs to the CinA family
Bsel_1809	COG1546	Belongs to the CinA family
Bsel_1810	COG0513	Belongs to the DEAD box helicase family
Bsel_1811	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Bsel_1812	COG1418	mRNA catabolic process
Bsel_1813	COG1692	metallophosphoesterase
Bsel_1814	COG2359	stage V sporulation protein S
Bsel_1816	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bsel_1816	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Bsel_1817	COG1013	pyruvate-flavodoxin oxidoreductase activity
Bsel_1818	COG1063	alcohol dehydrogenase
Bsel_1819	COG0156	8-amino-7-oxononanoate synthase activity
Bsel_1820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bsel_1821	COG4550	Control of competence regulator ComK, YlbF/YmcA
Bsel_1822	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Bsel_1825	COG2801	Transposase and inactivated derivatives
Bsel_1826	COG2521	methyltransferase
Bsel_1826	COG2136	Putative SAM-dependent methyltransferase
Bsel_1827	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Bsel_1828	COG1923	regulation of RNA biosynthetic process
Bsel_1830	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
Bsel_1831	COG0174	glutamine synthetase
Bsel_1832	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Bsel_1834	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Bsel_1835	COG4224	UPF0291 protein
Bsel_1836	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Bsel_1837	COG3763	UPF0154 protein
Bsel_1838	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Bsel_1839	COG1937	Protein conserved in bacteria
Bsel_1840	COG2217	Heavy metal translocating P-type atpase
Bsel_1844	COG4846	Membrane protein involved in cytochrome C biogenesis
Bsel_1849	COG1181	Belongs to the D-alanine--D-alanine ligase family
Bsel_1850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Bsel_1854	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
Bsel_1856	COG3300	MHYT domain
Bsel_1856	COG5001	Diguanylate cyclase
Bsel_1857	COG2508	Transcriptional regulator
Bsel_1858	COG0243	molybdopterin cofactor binding
Bsel_1860	COG3381	protein complex oligomerization
Bsel_1861	COG0243	molybdopterin cofactor binding
Bsel_1862	COG0437	4 iron, 4 sulfur cluster binding
Bsel_1864	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Bsel_1865	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
Bsel_1866	COG0840	transmembrane signaling receptor activity
Bsel_1873	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Bsel_1876	COG0464	growth
Bsel_1877	COG0824	Thioesterase
Bsel_1879	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Bsel_1880	COG0613	PHP domain protein
Bsel_1889	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Bsel_1891	COG1131	(ABC) transporter
Bsel_1892	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Bsel_1893	COG1725	Transcriptional regulator
Bsel_1894	COG1131	(ABC) transporter
Bsel_1897	COG0784	Response regulator, receiver
Bsel_1897	COG0835	chemotaxis
Bsel_1899	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bsel_1901	COG1418	mRNA catabolic process
Bsel_1902	COG0693	protein deglycase activity
Bsel_1904	COG2814	Major facilitator Superfamily
Bsel_1906	COG1111	helicase
Bsel_1906	COG1205	dead DEAH box helicase
Bsel_1907	COG3359	exonuclease
Bsel_1910	COG4474	Belongs to the UPF0398 family
Bsel_1911	COG3599	regulation of cell shape
Bsel_1912	COG0328	RNA-DNA hybrid ribonuclease activity
Bsel_1913	COG0116	Belongs to the methyltransferase superfamily
Bsel_1914	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Bsel_1916	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Bsel_1917	COG1125	glycine betaine transport
Bsel_1917	COG0517	IMP dehydrogenase activity
Bsel_1918	COG1174	glycine betaine transport
Bsel_1920	COG1832	CoA-binding protein
Bsel_1921	COG0187	DNA topoisomerase II activity
Bsel_1922	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Bsel_1924	COG0561	phosphatase activity
Bsel_1926	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Bsel_1931	COG1408	metallophosphoesterase
Bsel_1933	COG2996	Protein conserved in bacteria
Bsel_1934	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Bsel_1936	COG0371	Dehydrogenase
Bsel_1937	COG2176	DNA-directed DNA polymerase activity
Bsel_1939	COG0004	ammonium transporteR
Bsel_1941	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
Bsel_1943	COG3830	Belongs to the UPF0237 family
Bsel_1950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Bsel_1951	COG1917	Cupin 2, conserved barrel domain protein
Bsel_1953	COG3180	Ammonia monooxygenase
Bsel_1954	COG0582	viral genome integration into host DNA
Bsel_1955	COG3011	Protein conserved in bacteria
Bsel_1957	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Bsel_1960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Bsel_1962	COG0165	Argininosuccinate lyase
Bsel_1963	COG0137	argininosuccinate synthase activity
Bsel_1964	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Bsel_1965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Bsel_1967	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Bsel_1968	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Bsel_1969	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Bsel_1970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Bsel_1971	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bsel_1973	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bsel_1974	COG1764	response to oxidative stress
Bsel_1978	COG1454	alcohol dehydrogenase
Bsel_1978	COG1012	belongs to the aldehyde dehydrogenase family
Bsel_1979	COG0488	(ABC) transporter
Bsel_1981	COG0419	ATPase involved in DNA repair
Bsel_1982	COG0420	3'-5' exonuclease activity
Bsel_1983	COG1074	ATP-dependent DNA helicase activity
Bsel_1984	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Bsel_1986	COG0398	Pfam SNARE associated Golgi protein
Bsel_1987	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bsel_1988	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Bsel_1991	COG1882	Formate acetyltransferase
Bsel_1993	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Bsel_1996	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Bsel_2001	COG1283	sodium-dependent phosphate transmembrane transporter activity
Bsel_2003	COG0247	lactate metabolic process
Bsel_2005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Bsel_2010	COG2056	Na+-H+ antiporter family
Bsel_2012	COG0525	valine-tRNA ligase activity
Bsel_2013	COG1668	transmembrane transport
Bsel_2014	COG4152	abc transporter atp-binding protein
Bsel_2020	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Bsel_2021	COG3706	GGDEF domain
Bsel_2021	COG0745	RESPONSE REGULATOR receiver
Bsel_2023	COG1597	lipid kinase activity
Bsel_2025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Bsel_2026	COG1067	ATP-dependent peptidase activity
Bsel_2027	COG5001	Diguanylate cyclase
Bsel_2030	COG2814	Major facilitator Superfamily
Bsel_2031	COG3344	reverse transcriptase
Bsel_2036	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bsel_2037	COG0583	DNA-binding transcription factor activity
Bsel_2040	COG2002	toxin-antitoxin pair type II binding
Bsel_2043	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
Bsel_2044	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bsel_2045	COG0567	Dehydrogenase, E1 component
Bsel_2046	COG0436	Aminotransferase
Bsel_2048	COG1686	Belongs to the peptidase S11 family
Bsel_2052	COG0114	fumarate hydratase activity
Bsel_2054	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Bsel_2055	COG1012	belongs to the aldehyde dehydrogenase family
Bsel_2056	COG1554	hydrolase, family 65, central catalytic
Bsel_2057	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Bsel_2061	COG2814	Major facilitator Superfamily
Bsel_2063	COG4667	esterase of the alpha-beta hydrolase superfamily
Bsel_2066	COG1428	Deoxynucleoside kinase
Bsel_2067	COG1428	Deoxynucleoside kinase
Bsel_2070	COG0805	protein transport
Bsel_2073	COG1597	lipid kinase activity
Bsel_2076	COG3706	GGDEF domain
Bsel_2080	COG3428	Bacterial PH domain
Bsel_2081	COG3402	PFAM membrane-flanked domain
Bsel_2083	COG1413	lyase activity
Bsel_2085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bsel_2087	COG1335	isochorismatase
Bsel_2091	COG3331	DNA recombination
Bsel_2092	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bsel_2092	COG4499	WXG100 protein secretion system (Wss), protein YukC
Bsel_2093	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Bsel_2094	COG3935	DnaD domain protein
Bsel_2095	COG0017	Asparaginyl-tRNA synthetase
Bsel_2096	COG0436	Aminotransferase
Bsel_2098	COG0402	S-adenosylhomocysteine deaminase activity
Bsel_2099	COG1199	ATP-dependent helicase activity
Bsel_2099	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Bsel_2101	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Bsel_2103	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Bsel_2103	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Bsel_2104	COG0617	tRNA 3'-terminal CCA addition
Bsel_2105	COG0438	transferase activity, transferring glycosyl groups
Bsel_2106	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bsel_2107	COG1803	Methylglyoxal synthase
Bsel_2109	COG1694	Mazg nucleotide pyrophosphohydrolase
Bsel_2110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Bsel_2111	COG2738	Putative neutral zinc metallopeptidase
Bsel_2112	COG4347	Protein of unknown function (DUF1405)
Bsel_2113	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bsel_2113	COG2010	Cytochrome c
Bsel_2114	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Bsel_2115	COG0723	plastoquinol--plastocyanin reductase activity
Bsel_2117	COG5582	Belongs to the UPF0302 family
Bsel_2119	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Bsel_2120	COG0287	Prephenate dehydrogenase
Bsel_2121	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Bsel_2122	COG0159	tryptophan synthase activity
Bsel_2123	COG0133	tryptophan synthase activity
Bsel_2124	COG0134	indole-3-glycerol-phosphate synthase activity
Bsel_2125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Bsel_2127	COG4401	Chorismate mutase type I
Bsel_2128	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Bsel_2129	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Bsel_2130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Bsel_2131	COG0105	UTP biosynthetic process
Bsel_2132	COG0142	geranyltranstransferase activity
Bsel_2133	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
Bsel_2134	COG0109	protoheme IX farnesyltransferase activity
Bsel_2135	COG2226	methyltransferase
Bsel_2136	COG0142	geranyltranstransferase activity
Bsel_2138	COG0302	gtp cyclohydrolase
Bsel_2142	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Bsel_2143	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Bsel_2144	COG1160	GTP binding
Bsel_2146	COG0539	negative regulation of cytoplasmic translation
Bsel_2147	COG0204	Acyl-transferase
Bsel_2151	COG2339	peptidase activity
Bsel_2153	COG0492	ferredoxin-NADP+ reductase activity
Bsel_2154	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bsel_2163	COG1266	CAAX protease self-immunity
Bsel_2164	COG0514	ATP-dependent DNA helicase (RecQ)
Bsel_2166	COG1141	Ferredoxin
Bsel_2167	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Bsel_2169	COG2186	Transcriptional regulator
Bsel_2170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Bsel_2172	COG2096	Adenosyltransferase
Bsel_2173	COG0521	Mo-molybdopterin cofactor biosynthetic process
Bsel_2174	COG5002	protein histidine kinase activity
Bsel_2175	COG0745	RESPONSE REGULATOR receiver
Bsel_2176	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Bsel_2177	COG1333	cytochrome c biogenesis protein
Bsel_2178	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bsel_2179	COG1187	pseudouridine synthase activity
Bsel_2184	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Bsel_2185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Bsel_2186	COG1547	Domain of unknown function (DUF309)
Bsel_2187	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Bsel_2188	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Bsel_2188	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Bsel_2189	COG0307	riboflavin synthase, alpha
Bsel_2190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bsel_2190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Bsel_2194	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Bsel_2195	COG0019	diaminopimelate decarboxylase activity
Bsel_2197	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Bsel_2200	COG4974	Belongs to the 'phage' integrase family
Bsel_2201	COG0735	belongs to the Fur family
Bsel_2202	COG0494	nUDIX hydrolase
Bsel_2203	COG0667	Aldo Keto reductase
Bsel_2204	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bsel_2205	COG1968	undecaprenyl-diphosphatase activity
Bsel_2206	COG2190	(PTS) system
Bsel_2207	COG0561	phosphatase activity
Bsel_2211	COG1215	transferase activity, transferring glycosyl groups
Bsel_2213	COG1562	ergosterol biosynthetic process
Bsel_2218	COG2414	aldehyde ferredoxin oxidoreductase
Bsel_2220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Bsel_2222	COG0300	oxidoreductase activity
Bsel_2223	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Bsel_2226	COG0789	Transcriptional regulator
Bsel_2229	COG0517	IMP dehydrogenase activity
Bsel_2230	COG1902	pentaerythritol trinitrate reductase activity
Bsel_2233	COG1609	Transcriptional regulator
Bsel_2234	COG0366	Alpha amylase catalytic
Bsel_2235	COG1728	Protein conserved in bacteria
Bsel_2238	COG2257	FlhB HrpN YscU SpaS Family
Bsel_2240	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Bsel_2243	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bsel_2244	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Bsel_2245	COG0346	lactoylglutathione lyase activity
Bsel_2246	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bsel_2246	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bsel_2247	COG4129	membrane
Bsel_2251	COG0508	dehydrogenase complex catalyzes the overall conversion of
Bsel_2252	COG0022	dehydrogenase e1 component
Bsel_2253	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Bsel_2254	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Bsel_2257	COG0280	phosphate acetyltransferase
Bsel_2258	COG3290	protein histidine kinase activity
Bsel_2258	COG3829	transcription factor binding
Bsel_2260	COG0745	RESPONSE REGULATOR receiver
Bsel_2261	COG0497	DNA recombination
Bsel_2262	COG1438	arginine binding
Bsel_2263	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Bsel_2264	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Bsel_2266	COG0142	geranyltranstransferase activity
Bsel_2270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Bsel_2271	COG1302	Protein conserved in bacteria
Bsel_2272	COG0439	Biotin carboxylase
Bsel_2273	COG0511	ligase activity, forming carbon-carbon bonds
Bsel_2277	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Bsel_2278	COG0006	proline dipeptidase activity
Bsel_2281	COG1321	iron dependent repressor
Bsel_2283	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Bsel_2284	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bsel_2285	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Bsel_2287	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Bsel_2292	COG4537	Required for transformation and DNA binding
Bsel_2294	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Bsel_2295	COG4980	gas vesicle protein
Bsel_2300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bsel_2303	COG0011	TIGRFAM Protein of
Bsel_2305	COG0390	transport system, permease component
Bsel_2306	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Bsel_2307	COG1940	carbohydrate kinase activity
Bsel_2310	COG0457	Tetratricopeptide repeat
Bsel_2310	COG0705	Rhomboid family
Bsel_2312	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bsel_2313	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Bsel_2314	COG3481	metal-dependent phosphohydrolase, HD sub domain
Bsel_2315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Bsel_2319	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Bsel_2322	COG0704	Plays a role in the regulation of phosphate uptake
Bsel_2323	COG5521	maltodextrose utilization protein MalA
Bsel_2325	COG4086	secreted protein
Bsel_2326	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Bsel_2327	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
Bsel_2328	COG0735	belongs to the Fur family
Bsel_2329	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bsel_2330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bsel_2331	COG1121	(ABC) transporter
Bsel_2333	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Bsel_2335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Bsel_2336	COG1121	(ABC) transporter
Bsel_2337	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
Bsel_2338	COG0513	Belongs to the DEAD box helicase family
Bsel_2339	COG1329	Transcriptional regulator
Bsel_2340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Bsel_2341	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Bsel_2342	COG2384	SAM-dependent methyltransferase
Bsel_2344	COG0584	glycerophosphoryl diester phosphodiesterase
Bsel_2346	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Bsel_2347	COG0358	DNA primase activity
Bsel_2348	COG1671	Belongs to the UPF0178 family
Bsel_2349	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Bsel_2350	COG0517	IMP dehydrogenase activity
Bsel_2351	COG0751	glycine-tRNA ligase activity
Bsel_2352	COG0752	glycyl-tRNA synthetase alpha subunit
Bsel_2353	COG1381	Involved in DNA repair and RecF pathway recombination
Bsel_2354	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Bsel_2355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Bsel_2357	COG1480	7TM receptor with intracellular HD hydrolase
Bsel_2360	COG4864	UPF0365 protein
Bsel_2361	COG1030	water channel activity
Bsel_2362	COG1610	YqeY-like protein
Bsel_2363	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Bsel_2364	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Bsel_2365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Bsel_2366	COG2264	protein methyltransferase activity
Bsel_2367	COG0484	heat shock protein binding
Bsel_2368	COG0443	Heat shock 70 kDa protein
Bsel_2370	COG1420	regulation of RNA biosynthetic process
Bsel_2371	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Bsel_2372	COG0481	GTPase activity
Bsel_2373	COG0268	Binds directly to 16S ribosomal RNA
Bsel_2374	COG1466	dna polymerase III delta subunit
Bsel_2376	COG2333	competence protein COMEC
Bsel_2376	COG0658	competence protein
Bsel_2377	COG1596	polysaccharide export
Bsel_2377	COG1555	photosystem II stabilization
Bsel_2378	COG2226	methyltransferase
Bsel_2379	COG0799	negative regulation of ribosome biogenesis
Bsel_2380	COG1713	HD superfamily hydrolase involved in NAD metabolism
Bsel_2381	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Bsel_2382	COG1534	Rna-binding protein
Bsel_2384	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Bsel_2385	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
Bsel_2393	COG0247	lactate metabolic process
Bsel_2394	COG0277	FAD linked oxidase domain protein
Bsel_2395	COG3835	regulator
Bsel_2397	COG1183	phosphatidylcholine synthase activity
Bsel_2398	COG0617	tRNA 3'-terminal CCA addition
Bsel_2399	COG0450	alkyl hydroperoxide reductase
Bsel_2400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Bsel_2402	COG0095	Lipoate-protein ligase
Bsel_2404	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Bsel_2406	COG3300	MHYT domain
Bsel_2406	COG5001	Diguanylate cyclase
Bsel_2407	COG1151	hydroxylamine reductase activity
Bsel_2408	COG0484	heat shock protein binding
Bsel_2409	COG3447	MASE1 domain protein
Bsel_2409	COG5002	protein histidine kinase activity
Bsel_2409	COG5001	Diguanylate cyclase
Bsel_2414	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bsel_2415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Bsel_2416	COG0494	nUDIX hydrolase
Bsel_2418	COG2333	competence protein COMEC
Bsel_2418	COG0658	competence protein
Bsel_2420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bsel_2420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Bsel_2424	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Bsel_2425	COG1278	Cold shock
Bsel_2427	COG0803	Belongs to the bacterial solute-binding protein 9 family
Bsel_2428	COG1506	peptidase
Bsel_2428	COG0823	Involved in the tonB-independent uptake of proteins
Bsel_2428	COG4946	Tricorn protease homolog
Bsel_2430	COG0494	nUDIX hydrolase
Bsel_2431	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Bsel_2433	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Bsel_2434	COG0572	uridine kinase
Bsel_2439	COG3906	Belongs to the UPF0473 family
Bsel_2440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Bsel_2441	COG4472	Bacterial protein of unknown function (DUF965)
Bsel_2443	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Bsel_2445	COG0482	sulfurtransferase activity
Bsel_2446	COG1104	cysteine desulfurase activity
Bsel_2447	COG1959	2 iron, 2 sulfur cluster binding
Bsel_2448	COG2364	Membrane
Bsel_2449	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Bsel_2451	COG1556	Lactate utilization protein
Bsel_2452	COG1139	Iron-sulfur cluster binding protein
Bsel_2453	COG0247	lactate metabolic process
Bsel_2454	COG1620	l-lactate permease
Bsel_2455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Bsel_2457	COG0124	histidyl-tRNA synthetase
Bsel_2458	COG1490	D-aminoacyl-tRNA deacylase activity
Bsel_2460	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Bsel_2461	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Bsel_2461	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Bsel_2462	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bsel_2462	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bsel_2463	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bsel_2463	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Bsel_2466	COG1862	Preprotein translocase
Bsel_2467	COG0343	queuine tRNA-ribosyltransferase activity
Bsel_2471	COG0632	four-way junction helicase activity
Bsel_2472	COG0077	Prephenate dehydratase
Bsel_2473	COG4492	Belongs to the UPF0735 family
Bsel_2474	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Bsel_2476	COG0010	Belongs to the arginase family
Bsel_2479	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Bsel_2480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bsel_2481	COG0785	Cytochrome C biogenesis protein
Bsel_2482	COG1473	amidohydrolase
Bsel_2483	COG4473	ABC transporter
Bsel_2484	COG1131	(ABC) transporter
Bsel_2485	COG0537	adenosine 5'-monophosphoramidase activity
Bsel_2487	COG1846	Transcriptional regulator
Bsel_2491	COG3481	metal-dependent phosphohydrolase, HD sub domain
Bsel_2492	COG2205	protein histidine kinase activity
Bsel_2492	COG2770	Histidine kinase
Bsel_2493	COG0745	RESPONSE REGULATOR receiver
Bsel_2494	COG4717	serine-type aminopeptidase activity
Bsel_2495	COG0420	3'-5' exonuclease activity
Bsel_2499	COG4399	Belongs to the UPF0754 family
Bsel_2501	COG2508	Transcriptional regulator
Bsel_2502	COG3842	ATPase activity
Bsel_2503	COG4232	protein-disulfide reductase activity
Bsel_2504	COG0702	epimerase
Bsel_2506	COG1271	oxidase subunit
Bsel_2507	COG1294	oxidase, subunit
Bsel_2509	COG1131	(ABC) transporter
Bsel_2511	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Bsel_2511	COG1263	PTS System
Bsel_2512	COG2313	pseudouridylate synthase activity
Bsel_2518	COG1366	Belongs to the anti-sigma-factor antagonist family
Bsel_2520	COG0024	Methionine aminopeptidase
Bsel_2521	COG2814	Major facilitator Superfamily
Bsel_2523	COG0667	Aldo Keto reductase
Bsel_2528	COG0028	Belongs to the TPP enzyme family
Bsel_2529	COG0440	acetolactate synthase activity
Bsel_2530	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Bsel_2531	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Bsel_2532	COG0473	3-isopropylmalate dehydrogenase activity
Bsel_2533	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Bsel_2534	COG0066	3-isopropylmalate dehydratase activity
Bsel_2538	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Bsel_2540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Bsel_2541	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Bsel_2543	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Bsel_2544	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
Bsel_2545	COG3153	acetyltransferase
Bsel_2545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Bsel_2553	COG3192	ethanolamine utilization protein
Bsel_2554	COG1489	DNA binding
Bsel_2558	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Bsel_2563	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Bsel_2564	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Bsel_2566	COG0217	transcriptional regulatory protein
Bsel_2569	COG2188	Transcriptional regulator
Bsel_2570	COG1486	melibiose metabolic process
Bsel_2574	COG0640	Transcriptional regulator
Bsel_2575	COG0840	transmembrane signaling receptor activity
Bsel_2575	COG5278	phosphoserine phosphatase activity
Bsel_2578	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Bsel_2579	COG0765	amino acid transport
Bsel_2580	COG1126	abc transporter atp-binding protein
Bsel_2583	COG0840	transmembrane signaling receptor activity
Bsel_2585	COG0840	transmembrane signaling receptor activity
Bsel_2587	COG2357	RelA SpoT domain protein
Bsel_2588	COG2149	membrane
Bsel_2590	COG5609	conserved protein (DUF2294)
Bsel_2593	COG3639	organic phosphonate transmembrane transporter activity
Bsel_2594	COG3639	organic phosphonate transmembrane transporter activity
Bsel_2595	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Bsel_2597	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Bsel_2598	COG1116	anion transmembrane transporter activity
Bsel_2599	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bsel_2600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bsel_2605	COG3381	protein complex oligomerization
Bsel_2606	COG0437	4 iron, 4 sulfur cluster binding
Bsel_2607	COG0243	molybdopterin cofactor binding
Bsel_2609	COG4585	Histidine kinase
Bsel_2612	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_2614	COG0477	Major facilitator Superfamily
Bsel_2617	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_2620	COG0154	amidase activity
Bsel_2623	COG0840	transmembrane signaling receptor activity
Bsel_2626	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Bsel_2627	COG0574	Belongs to the PEP-utilizing enzyme family
Bsel_2627	COG3848	Pyruvate phosphate dikinase
Bsel_2628	COG1309	transcriptional regulator
Bsel_2633	COG2336	PFAM SpoVT AbrB
Bsel_2635	COG0602	queuosine metabolic process
Bsel_2636	COG0720	synthase
Bsel_2637	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Bsel_2640	COG1840	ABC-type Fe3 transport system, periplasmic component
Bsel_2641	COG1178	ABC-type Fe3 transport system permease component
Bsel_2643	COG3842	ATPase activity
Bsel_2647	COG0840	transmembrane signaling receptor activity
Bsel_2649	COG2205	protein histidine kinase activity
Bsel_2650	COG0745	RESPONSE REGULATOR receiver
Bsel_2651	COG1136	(ABC) transporter
Bsel_2652	COG0577	efflux transmembrane transporter activity
Bsel_2655	COG2801	Transposase and inactivated derivatives
Bsel_2658	COG0537	adenosine 5'-monophosphoramidase activity
Bsel_2660	COG3344	reverse transcriptase
Bsel_2666	COG0726	polysaccharide deacetylase
Bsel_2667	COG3706	GGDEF domain
Bsel_2673	COG1309	transcriptional regulator
Bsel_2679	COG1528	Iron-storage protein
Bsel_2683	COG2195	Cleaves the N-terminal amino acid of tripeptides
Bsel_2687	COG1131	(ABC) transporter
Bsel_2689	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Bsel_2690	COG2022	thiamine diphosphate biosynthetic process
Bsel_2692	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Bsel_2693	COG0352	thiamine-phosphate diphosphorylase activity
Bsel_2694	COG5646	InterPro IPR014922
Bsel_2695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Bsel_2698	COG1733	regulation of RNA biosynthetic process
Bsel_2699	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Bsel_2701	COG1116	anion transmembrane transporter activity
Bsel_2701	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Bsel_2702	COG0789	Transcriptional regulator
Bsel_2708	COG0673	inositol 2-dehydrogenase activity
Bsel_2711	COG3436	PFAM IS66 Orf2 family protein
Bsel_2712	COG4372	Transposase
Bsel_2716	COG0735	belongs to the Fur family
Bsel_2721	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Bsel_2722	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Bsel_2723	COG0070	glutamate synthase
Bsel_2723	COG0069	glutamate synthase activity
Bsel_2723	COG0067	glutamate synthase
Bsel_2724	COG4129	membrane
Bsel_2726	COG1132	(ABC) transporter
Bsel_2727	COG3557	Belongs to the UPF0374 family
Bsel_2732	COG0745	RESPONSE REGULATOR receiver
Bsel_2733	COG2059	Chromate
Bsel_2734	COG2059	Chromate
Bsel_2736	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_2737	COG1194	a g-specific adenine glycosylase
Bsel_2738	COG1988	membrane-bound metal-dependent
Bsel_2741	COG2137	regulation of response to DNA damage stimulus
Bsel_2742	COG1090	epimerase
Bsel_2744	COG2188	Transcriptional regulator
Bsel_2745	COG0366	Alpha amylase catalytic
Bsel_2746	COG0679	Auxin Efflux Carrier
Bsel_2750	COG0492	ferredoxin-NADP+ reductase activity
Bsel_2759	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Bsel_2760	COG0406	alpha-ribazole phosphatase activity
Bsel_2764	COG0535	radical SAM domain protein
Bsel_2765	COG0534	Mate efflux family protein
Bsel_2766	COG0477	Major facilitator Superfamily
Bsel_2777	COG1254	Belongs to the acylphosphatase family
Bsel_2781	COG1012	belongs to the aldehyde dehydrogenase family
Bsel_2783	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Bsel_2784	COG0288	reversible hydration of carbon dioxide
Bsel_2785	COG0425	Belongs to the sulfur carrier protein TusA family
Bsel_2786	COG0425	Belongs to the sulfur carrier protein TusA family
Bsel_2786	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bsel_2788	COG1215	transferase activity, transferring glycosyl groups
Bsel_2789	COG0628	permease
Bsel_2795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Bsel_2796	COG0400	carboxylic ester hydrolase activity
Bsel_2797	COG0514	ATP-dependent DNA helicase (RecQ)
Bsel_2798	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Bsel_2799	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
Bsel_2800	COG0840	transmembrane signaling receptor activity
Bsel_2802	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Bsel_2803	COG1132	(ABC) transporter
Bsel_2804	COG1132	(ABC) transporter
Bsel_2805	COG1929	Belongs to the glycerate kinase type-1 family
Bsel_2806	COG0366	Alpha amylase catalytic
Bsel_2807	COG2962	Rard protein
Bsel_2808	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_2809	COG2153	protein acetylation
Bsel_2812	COG4895	conserved protein (DUF2196)
Bsel_2813	COG5002	protein histidine kinase activity
Bsel_2813	COG3447	MASE1 domain protein
Bsel_2813	COG5001	Diguanylate cyclase
Bsel_2816	COG1554	hydrolase, family 65, central catalytic
Bsel_2817	COG1028	Short-chain dehydrogenase reductase Sdr
Bsel_2818	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bsel_2819	COG4605	iron ion homeostasis
Bsel_2820	COG4604	ABC transporter, ATP-binding protein
Bsel_2821	COG4607	ABC-type enterochelin transport system periplasmic component
Bsel_2822	COG0194	GDP metabolic process
Bsel_2823	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Bsel_2825	COG1070	Carbohydrate kinase
Bsel_2826	COG2115	Belongs to the xylose isomerase family
Bsel_2827	COG1940	carbohydrate kinase activity
Bsel_2830	COG2972	Histidine kinase
Bsel_2831	COG4753	response regulator
Bsel_2831	COG2207	Transcriptional regulator
Bsel_2832	COG1653	transport
Bsel_2833	COG1175	transmembrane transport
Bsel_2835	COG3507	Belongs to the glycosyl hydrolase 43 family
Bsel_2836	COG5578	integral membrane protein
Bsel_2837	COG0318	PFAM AMP-dependent synthetase and ligase
Bsel_2842	COG5487	UPF0391 membrane protein
Bsel_2843	COG5487	UPF0391 membrane protein
Bsel_2844	COG0471	metal ion transport
Bsel_2844	COG0490	domain, Protein
Bsel_2845	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Bsel_2846	COG1388	LysM domain
Bsel_2846	COG3584	3D domain protein
Bsel_2847	COG2105	PFAM AIG2 family protein
Bsel_2851	COG1013	pyruvate-flavodoxin oxidoreductase activity
Bsel_2852	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Bsel_2852	COG0674	pyruvate-flavodoxin oxidoreductase activity
Bsel_2855	COG3706	GGDEF domain
Bsel_2857	COG0179	Fumarylacetoacetate (FAA) hydrolase
Bsel_2858	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Bsel_2859	COG3300	MHYT domain
Bsel_2859	COG5001	Diguanylate cyclase
Bsel_2860	COG0840	transmembrane signaling receptor activity
Bsel_2863	COG2391	methyltransferase activity
Bsel_2865	COG0425	Belongs to the sulfur carrier protein TusA family
Bsel_2865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Bsel_2866	COG2897	thiosulfate sulfurtransferase activity
Bsel_2870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Bsel_2871	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Bsel_2875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bsel_2881	COG3973	AAA domain
Bsel_2882	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Bsel_2885	COG1309	transcriptional regulator
Bsel_2892	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Bsel_2897	COG1309	transcriptional regulator
Bsel_2898	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Bsel_2899	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Bsel_2900	COG1120	ATPase activity
Bsel_2902	COG0395	ABC-type sugar transport system, permease component
Bsel_2903	COG1175	transmembrane transport
Bsel_2904	COG3842	ATPase activity
Bsel_2907	COG0588	phosphoglycerate mutase activity
Bsel_2910	COG0840	transmembrane signaling receptor activity
Bsel_2911	COG2217	Heavy metal translocating P-type atpase
Bsel_2913	COG4187	Peptidase family M20/M25/M40
Bsel_2915	COG3447	MASE1 domain protein
Bsel_2915	COG5002	protein histidine kinase activity
Bsel_2915	COG5001	Diguanylate cyclase
Bsel_2916	COG0671	phosphoesterase, PA-phosphatase related
Bsel_2918	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Bsel_2920	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Bsel_2923	COG1910	domain protein
Bsel_2924	COG2346	COG2346, Truncated hemoglobins
Bsel_2928	COG0667	Aldo Keto reductase
Bsel_2929	COG0561	phosphatase activity
Bsel_2931	COG2514	catechol 2,3-dioxygenase activity
Bsel_2932	COG1104	cysteine desulfurase activity
Bsel_2933	COG0673	inositol 2-dehydrogenase activity
Bsel_2935	COG0673	inositol 2-dehydrogenase activity
Bsel_2936	COG1082	Xylose isomerase domain protein TIM barrel
Bsel_2938	COG0110	maltose O-acetyltransferase activity
Bsel_2939	COG2066	Belongs to the glutaminase family
Bsel_2942	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Bsel_2943	COG2199	diguanylate cyclase activity
Bsel_2945	COG3706	GGDEF domain
Bsel_2946	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
Bsel_2947	COG1012	belongs to the aldehyde dehydrogenase family
Bsel_2951	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
Bsel_2956	COG2801	Transposase and inactivated derivatives
Bsel_2966	COG1396	sequence-specific DNA binding
Bsel_2969	COG1484	DNA-dependent DNA replication
Bsel_2974	COG2801	Transposase and inactivated derivatives
Bsel_2976	COG2801	Transposase and inactivated derivatives
Bsel_2991	COG3409	Peptidoglycan-binding domain 1 protein
Bsel_2991	COG5632	N-Acetylmuramoyl-L-alanine amidase
Bsel_3006	COG0740	serine-type endopeptidase activity
Bsel_3007	COG4695	Portal protein
Bsel_3035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Bsel_3039	COG2244	polysaccharide biosynthetic process
Bsel_3040	COG1216	Glycosyl transferase, family 2
Bsel_3040	COG1442	glycosyl transferase family 8
Bsel_3043	COG0438	transferase activity, transferring glycosyl groups
Bsel_3045	COG0438	transferase activity, transferring glycosyl groups
Bsel_3046	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Bsel_3051	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Bsel_3053	COG4464	protein tyrosine phosphatase activity
Bsel_3054	COG0489	protein tyrosine kinase activity
Bsel_3055	COG3944	biosynthesis protein
Bsel_3063	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
Bsel_3064	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Bsel_3065	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Bsel_3069	COG0791	NLP P60 protein
Bsel_3071	COG1404	Belongs to the peptidase S8 family
Bsel_3072	COG5263	repeat protein
Bsel_3072	COG4193	domain, Protein
Bsel_3075	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Bsel_3075	COG2755	lipolytic protein G-D-S-L family
Bsel_3078	COG2843	Capsule synthesis protein
Bsel_3080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Bsel_3081	COG1388	LysM domain
Bsel_3081	COG0791	NLP P60 protein
Bsel_3082	COG0791	NLP P60 protein
Bsel_3082	COG0791	NLP P60 protein
Bsel_3082	COG3883	PFAM NLP P60 protein
Bsel_3082	COG3883	PFAM NLP P60 protein
Bsel_3083	COG1316	TRANSCRIPTIONal
Bsel_3084	COG0840	transmembrane signaling receptor activity
Bsel_3090	COG0840	transmembrane signaling receptor activity
Bsel_3093	COG2244	polysaccharide biosynthetic process
Bsel_3100	COG0437	4 iron, 4 sulfur cluster binding
Bsel_3101	COG0243	molybdopterin cofactor binding
Bsel_3104	COG0437	4 iron, 4 sulfur cluster binding
Bsel_3105	COG0243	molybdopterin cofactor binding
Bsel_3108	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bsel_3110	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
Bsel_3111	COG4869	propanediol catabolic process
Bsel_3112	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Bsel_3113	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
Bsel_3118	COG0235	Class ii aldolase
Bsel_3119	COG1349	DNA-binding transcription factor activity
Bsel_3120	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Bsel_3121	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
Bsel_3122	COG1172	Belongs to the binding-protein-dependent transport system permease family
Bsel_3123	COG1129	ABC transporter
Bsel_3126	COG0745	RESPONSE REGULATOR receiver
Bsel_3135	COG4786	Flagellar basal body rod
Bsel_3136	COG4786	Flagellar basal body rod
Bsel_3137	COG1077	Cell shape determining protein MreB Mrl
Bsel_3138	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Bsel_3140	COG1007	ATP synthesis coupled electron transport
Bsel_3141	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bsel_3142	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Bsel_3143	COG0713	ATP synthesis coupled electron transport
Bsel_3144	COG0839	Belongs to the complex I subunit 6 family
Bsel_3145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bsel_3146	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Bsel_3147	COG0649	NAD binding
Bsel_3148	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bsel_3149	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Bsel_3151	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Bsel_3152	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Bsel_3154	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Bsel_3158	COG0356	it plays a direct role in the translocation of protons across the membrane
Bsel_3161	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Bsel_3162	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Bsel_3163	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Bsel_3164	COG5001	Diguanylate cyclase
Bsel_3168	COG0698	ribose 5-phosphate isomerase
Bsel_3171	COG0009	L-threonylcarbamoyladenylate synthase
Bsel_3172	COG2890	protein-(glutamine-N5) methyltransferase activity
Bsel_3173	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Bsel_3174	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bsel_3175	COG0840	transmembrane signaling receptor activity
Bsel_3176	COG1435	thymidine kinase activity
Bsel_3177	COG0254	rRNA binding
Bsel_3178	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Bsel_3179	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Bsel_3180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Bsel_3182	COG2204	response regulator
Bsel_3184	COG0504	CTP synthase activity
Bsel_3185	COG3343	RNA polymerase activity
Bsel_3186	COG1703	isobutyryl-CoA mutase activity
Bsel_3186	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bsel_3186	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Bsel_3188	COG1960	acyl-CoA dehydrogenase activity
Bsel_3189	COG1960	acyl-CoA dehydrogenase activity
Bsel_3190	COG1250	3-hydroxyacyl-CoA dehydrogenase
Bsel_3191	COG0183	Belongs to the thiolase family
Bsel_3192	COG0247	lactate metabolic process
Bsel_3192	COG2181	nitrate reductase activity
Bsel_3194	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Bsel_3197	COG1132	(ABC) transporter
Bsel_3199	COG1131	(ABC) transporter
Bsel_3200	COG1725	Transcriptional regulator
Bsel_3202	COG0840	transmembrane signaling receptor activity
Bsel_3203	COG0018	arginyl-trna synthetase
Bsel_3205	COG3620	sequence-specific DNA binding
Bsel_3206	COG4608	Belongs to the ABC transporter superfamily
Bsel_3207	COG0444	Belongs to the ABC transporter superfamily
Bsel_3208	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Bsel_3209	COG0601	transmembrane transport
Bsel_3212	COG0010	Belongs to the arginase family
Bsel_3216	COG1078	dGTPase activity
Bsel_3217	COG4844	belongs to the
Bsel_3218	COG0095	Lipoate-protein ligase
Bsel_3220	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Bsel_3221	COG0280	phosphate acetyltransferase
Bsel_3222	COG1902	pentaerythritol trinitrate reductase activity
Bsel_3222	COG0446	pyridine nucleotide-disulphide oxidoreductase
Bsel_3223	COG1024	Enoyl-CoA hydratase
Bsel_3226	COG0395	ABC-type sugar transport system, permease component
Bsel_3227	COG1175	transmembrane transport
Bsel_3228	COG1653	transport
Bsel_3230	COG2363	Small membrane protein
Bsel_3235	COG5002	protein histidine kinase activity
Bsel_3236	COG2084	Dehydrogenase
Bsel_3238	COG2201	protein-glutamate methylesterase activity
Bsel_3239	COG1621	beta-fructofuranosidase activity
Bsel_3241	COG0840	transmembrane signaling receptor activity
Bsel_3242	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bsel_3243	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Bsel_3245	COG1368	sulfuric ester hydrolase activity
Bsel_3246	COG2309	aminopeptidase activity
Bsel_3249	COG1072	(Pantothenic acid kinase))
Bsel_3253	COG1794	racemase activity, acting on amino acids and derivatives
Bsel_3254	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Bsel_3255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Bsel_3256	COG0706	membrane insertase activity
Bsel_3261	COG0460	homoserine dehydrogenase
Bsel_3262	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Bsel_3263	COG0083	homoserine kinase activity
Bsel_3264	COG0561	phosphatase activity
Bsel_3265	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Bsel_3267	COG0527	aspartate kinase activity
Bsel_3268	COG0747	negative chemotaxis
Bsel_3271	COG0444	Belongs to the ABC transporter superfamily
Bsel_3272	COG4608	Belongs to the ABC transporter superfamily
Bsel_3273	COG1213	nucleotidyl transferase
Bsel_3273	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Bsel_3274	COG3842	ATPase activity
Bsel_3277	COG4134	Bacterial extracellular solute-binding protein
Bsel_3278	COG0398	Pfam SNARE associated Golgi protein
Bsel_3279	COG2897	thiosulfate sulfurtransferase activity
Bsel_3281	COG0493	'glutamate synthase
Bsel_3282	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Bsel_3283	COG3706	GGDEF domain
Bsel_3284	COG2197	response regulator
Bsel_3285	COG4585	Histidine kinase
Bsel_3286	COG3239	Fatty acid desaturase
Bsel_3288	COG1131	(ABC) transporter
Bsel_3289	COG2199	diguanylate cyclase activity
Bsel_3290	COG0579	oxidoreductase
Bsel_3294	COG1187	pseudouridine synthase activity
Bsel_3295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Bsel_3297	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Bsel_3298	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Bsel_3299	COG4853	Protein conserved in bacteria
Bsel_3300	COG4863	YycH protein
Bsel_3301	COG5002	protein histidine kinase activity
Bsel_3302	COG0745	RESPONSE REGULATOR receiver
Bsel_3303	COG0741	lytic transglycosylase activity
Bsel_3303	COG1196	nuclear chromosome segregation
Bsel_3303	COG0739	heme binding
Bsel_3304	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Bsel_3305	COG0305	Participates in initiation and elongation during chromosome replication
Bsel_3306	COG0359	binds to the 23S rRNA
Bsel_3307	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
Bsel_3308	COG4241	membrane
Bsel_3309	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Bsel_3310	COG0629	single-stranded DNA binding
Bsel_3311	COG0360	Binds together with S18 to 16S ribosomal RNA
Bsel_3312	COG0012	GTP binding
Bsel_3313	COG4481	Protein conserved in bacteria
Bsel_3314	COG1811	Na channel or pump
Bsel_3315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Bsel_3316	COG1475	DNA binding
Bsel_3317	COG1192	Involved in chromosome partitioning
Bsel_3318	COG1475	DNA binding
Bsel_3320	COG0445	tRNA wobble uridine modification
Bsel_3321	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Bsel_3322	COG1847	R3H domain protein
Bsel_3323	COG0706	membrane insertase activity
Bsel_3324	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Bsel_3326	COG0230	Belongs to the bacterial ribosomal protein bL34 family
