locus-tag	class	description
LYZ33_00010	COG0592	DNA-directed DNA polymerase activity
LYZ33_00015	COG2501	S4 domain
LYZ33_00030	COG0187	DNA topoisomerase II activity
LYZ33_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LYZ33_00070	COG0516	GMP reductase activity
LYZ33_00070	COG0517	IMP dehydrogenase activity
LYZ33_00075	COG1686	Belongs to the peptidase S11 family
LYZ33_00095	COG1929	Belongs to the glycerate kinase type-1 family
LYZ33_00105	COG1428	Deoxynucleoside kinase
LYZ33_00110	COG1428	Deoxynucleoside kinase
LYZ33_00115	COG1388	LysM domain
LYZ33_00115	COG3858	chitin binding
LYZ33_00120	COG1335	isochorismatase
LYZ33_00125	COG0590	tRNA wobble adenosine to inosine editing
LYZ33_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LYZ33_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LYZ33_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LYZ33_00195	COG3853	Toxic anion resistance protein (TelA)
LYZ33_00200	COG1982	Orn Lys Arg decarboxylase major
LYZ33_00210	COG3870	Protein conserved in bacteria
LYZ33_00215	COG1728	Protein conserved in bacteria
LYZ33_00220	COG0470	DNA polymerase III
LYZ33_00225	COG1774	PSP1 C-terminal conserved region
LYZ33_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LYZ33_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LYZ33_00250	COG2002	toxin-antitoxin pair type II binding
LYZ33_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LYZ33_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LYZ33_00260	COG0084	hydrolase, TatD family'
LYZ33_00265	COG3583	domain protein
LYZ33_00265	COG3584	3D domain protein
LYZ33_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LYZ33_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LYZ33_00285	COG4466	Protein conserved in bacteria
LYZ33_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LYZ33_00305	COG0251	oxidation-reduction process
LYZ33_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LYZ33_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LYZ33_00345	COG2002	toxin-antitoxin pair type II binding
LYZ33_00350	COG2244	polysaccharide biosynthetic process
LYZ33_00355	COG3956	TIGRFAM MazG family protein
LYZ33_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LYZ33_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LYZ33_00380	COG1098	S1 RNA binding domain
LYZ33_00395	COG2208	phosphoserine phosphatase activity
LYZ33_00400	COG2304	oxidoreductase activity
LYZ33_00405	COG0515	serine threonine protein kinase
LYZ33_00410	COG0037	tRNA processing
LYZ33_00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LYZ33_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LYZ33_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LYZ33_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LYZ33_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LYZ33_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
LYZ33_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LYZ33_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LYZ33_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LYZ33_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LYZ33_00475	COG1396	sequence-specific DNA binding
LYZ33_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LYZ33_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LYZ33_00565	COG4463	regulation of RNA biosynthetic process
LYZ33_00570	COG3880	PFAM UvrB UvrC protein
LYZ33_00580	COG0542	response to heat
LYZ33_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LYZ33_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LYZ33_00595	COG4956	integral membrane protein (PIN domain superfamily)
LYZ33_00615	COG1045	serine acetyltransferase
LYZ33_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LYZ33_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LYZ33_00635	COG3688	RNA-binding protein containing a PIN domain
LYZ33_00640	COG1595	DNA-templated transcription, initiation
LYZ33_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LYZ33_00655	COG0250	Participates in transcription elongation, termination and antitermination
LYZ33_00680	COG2813	Specifically methylates the guanine in position
LYZ33_00695	COG1358	cellular component organization or biogenesis
LYZ33_00720	COG0596	Alpha beta hydrolase
LYZ33_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LYZ33_00830	COG0201	protein transport
LYZ33_00840	COG0024	Methionine aminopeptidase
LYZ33_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LYZ33_00880	COG1122	ATPase activity
LYZ33_00885	COG1122	ATPase activity
LYZ33_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LYZ33_00910	COG2226	methyltransferase
LYZ33_00915	COG2318	DinB family
LYZ33_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
LYZ33_00930	COG0489	protein tyrosine kinase activity
LYZ33_00940	COG2194	sulfuric ester hydrolase activity
LYZ33_00945	COG0726	polysaccharide deacetylase
LYZ33_01005	COG0738	Major facilitator superfamily
LYZ33_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LYZ33_01020	COG1063	alcohol dehydrogenase
LYZ33_01025	COG0659	secondary active sulfate transmembrane transporter activity
LYZ33_01030	COG0385	Bile acid
LYZ33_01035	COG2819	hydrolase of the alpha beta superfamily
LYZ33_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LYZ33_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LYZ33_01055	COG2207	Transcriptional regulator
LYZ33_01060	COG3876	Protein conserved in bacteria
LYZ33_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
LYZ33_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LYZ33_01075	COG1263	PTS System
LYZ33_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LYZ33_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LYZ33_01090	COG1683	Conserved Protein
LYZ33_01120	COG1595	DNA-templated transcription, initiation
LYZ33_01125	COG5662	AntiSigma factor
LYZ33_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LYZ33_01135	COG4856	YbbR-like protein
LYZ33_01160	COG0515	serine threonine protein kinase
LYZ33_01170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LYZ33_01180	COG1346	cytolysis
LYZ33_01185	COG1380	Effector of murein hydrolase LrgA
LYZ33_01190	COG1846	Transcriptional regulator
LYZ33_01195	COG1113	amino acid transport
LYZ33_01200	COG1011	Hydrolase
LYZ33_01205	COG4585	Histidine kinase
LYZ33_01210	COG2197	response regulator
LYZ33_01215	COG1131	(ABC) transporter
LYZ33_01255	COG0531	amino acid
LYZ33_01270	COG0584	glycerophosphoryl diester phosphodiesterase
LYZ33_01275	COG2271	Major facilitator Superfamily
LYZ33_01285	COG2368	4-hydroxyphenylacetate
LYZ33_01295	COG3409	Peptidoglycan-binding domain 1 protein
LYZ33_01310	COG0371	Dehydrogenase
LYZ33_01320	COG1183	phosphatidylcholine synthase activity
LYZ33_01325	COG0586	Pfam SNARE associated Golgi protein
LYZ33_01330	COG0688	phosphatidylethanolamine metabolic process
LYZ33_01345	COG1301	dicarboxylic acid transport
LYZ33_01350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LYZ33_01355	COG0833	amino acid
LYZ33_01360	COG2040	homocysteine
LYZ33_01365	COG1115	amino acid carrier protein
LYZ33_01370	COG2066	Belongs to the glutaminase family
LYZ33_01375	COG4191	Histidine kinase
LYZ33_01380	COG0784	Response regulator, receiver
LYZ33_01385	COG3173	Aminoglycoside phosphotransferase
LYZ33_01395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LYZ33_01400	COG0778	Nitroreductase
LYZ33_01405	COG0346	lactoylglutathione lyase activity
LYZ33_01410	COG2259	Doxx family
LYZ33_01415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_01425	COG3773	Cell wall hydrolase
LYZ33_01430	COG3540	Alkaline phosphatase
LYZ33_01435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LYZ33_01440	COG0805	protein transport
LYZ33_01450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LYZ33_01455	COG0477	Major facilitator Superfamily
LYZ33_01460	COG1309	transcriptional regulator
LYZ33_01465	COG0252	asparaginase activity
LYZ33_01470	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LYZ33_01475	COG3012	SEC-C Motif Domain Protein
LYZ33_01475	COG1405	negative regulation of cell septum assembly
LYZ33_01480	COG0667	Aldo Keto reductase
LYZ33_01490	COG1595	DNA-templated transcription, initiation
LYZ33_01495	COG1595	DNA-templated transcription, initiation
LYZ33_01500	COG1876	peptidase activity
LYZ33_01505	COG0457	Tetratricopeptide repeat
LYZ33_01510	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_01515	COG0366	Alpha amylase catalytic
LYZ33_01520	COG0803	Belongs to the bacterial solute-binding protein 9 family
LYZ33_01525	COG1121	(ABC) transporter
LYZ33_01530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LYZ33_01535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LYZ33_01540	COG2310	stress, protein
LYZ33_01545	COG2310	stress, protein
LYZ33_01550	COG2310	stress, protein
LYZ33_01555	COG0861	Integral membrane protein TerC family
LYZ33_01565	COG3853	Toxic anion resistance protein (TelA)
LYZ33_01570	COG0477	Major facilitator Superfamily
LYZ33_01575	COG2814	Major facilitator Superfamily
LYZ33_01580	COG0640	Transcriptional regulator
LYZ33_01585	COG0517	IMP dehydrogenase activity
LYZ33_01585	COG4175	Glycine betaine
LYZ33_01590	COG4176	ABC-type proline glycine betaine transport system permease component
LYZ33_01595	COG2113	Glycine betaine
LYZ33_01600	COG1473	amidohydrolase
LYZ33_01605	COG1288	antiporter activity
LYZ33_01615	COG0366	Alpha amylase catalytic
LYZ33_01625	COG2814	Major facilitator Superfamily
LYZ33_01630	COG1846	Transcriptional regulator
LYZ33_01635	COG1280	lysine exporter protein (LysE YggA)
LYZ33_01640	COG3403	YqcI/YcgG family
LYZ33_01645	COG1113	amino acid transport
LYZ33_01650	COG3665	Urea carboxylase-associated protein
LYZ33_01665	COG1660	Displays ATPase and GTPase activities
LYZ33_01675	COG2271	Major facilitator Superfamily
LYZ33_01680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LYZ33_01685	COG3458	cephalosporin-C deacetylase activity
LYZ33_01690	COG3541	Predicted nucleotidyltransferase
LYZ33_01695	COG0506	proline dehydrogenase activity
LYZ33_01700	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_01705	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LYZ33_01710	COG2508	Transcriptional regulator
LYZ33_01720	COG1587	Uroporphyrinogen-III synthase
LYZ33_01720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LYZ33_01725	COG2146	nitrite reductase [NAD(P)H] activity
LYZ33_01730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LYZ33_01740	COG0523	cobalamin synthesis protein
LYZ33_01745	COG1063	alcohol dehydrogenase
LYZ33_01750	COG1714	RDD family
LYZ33_01760	COG2723	6-phospho-beta-galactosidase activity
LYZ33_01775	COG3209	COG3209 Rhs family protein
LYZ33_01780	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LYZ33_01785	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LYZ33_01790	COG1733	regulation of RNA biosynthetic process
LYZ33_01795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_01815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_01820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_01825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LYZ33_01840	COG0697	spore germination
LYZ33_01845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LYZ33_01855	COG2364	Membrane
LYZ33_01860	COG1126	abc transporter atp-binding protein
LYZ33_01865	COG0765	amino acid transport
LYZ33_01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LYZ33_01875	COG0583	DNA-binding transcription factor activity
LYZ33_01880	COG0163	prenyltransferase activity
LYZ33_01885	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LYZ33_01900	COG3104	oligopeptide transport
LYZ33_01905	COG5434	Belongs to the glycosyl hydrolase 28 family
LYZ33_01915	COG0697	spore germination
LYZ33_01925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LYZ33_01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LYZ33_01935	COG0456	acetyltransferase
LYZ33_01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LYZ33_01945	COG0765	amino acid transport
LYZ33_01950	COG1126	abc transporter atp-binding protein
LYZ33_01955	COG1473	amidohydrolase
LYZ33_01960	COG2079	MmgE PrpD family protein
LYZ33_01965	COG1136	(ABC) transporter
LYZ33_01970	COG0577	efflux transmembrane transporter activity
LYZ33_01975	COG0745	RESPONSE REGULATOR receiver
LYZ33_01980	COG5002	protein histidine kinase activity
LYZ33_01980	COG3850	Histidine kinase
LYZ33_01985	COG0457	Tetratricopeptide repeat
LYZ33_02000	COG0527	aspartate kinase activity
LYZ33_02005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_02010	COG4605	iron ion homeostasis
LYZ33_02015	COG4604	ABC transporter, ATP-binding protein
LYZ33_02020	COG4607	ABC-type enterochelin transport system periplasmic component
LYZ33_02025	COG2814	Major facilitator Superfamily
LYZ33_02030	COG1309	transcriptional regulator
LYZ33_02035	COG0778	Nitroreductase
LYZ33_02040	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LYZ33_02045	COG0640	Transcriptional regulator
LYZ33_02050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LYZ33_02055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LYZ33_02060	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_02065	COG4975	Glucose uptake
LYZ33_02070	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_02075	COG4549	nuclear export factor GLE1
LYZ33_02080	COG1276	copper resistance
LYZ33_02080	COG2372	response to copper ion
LYZ33_02085	COG1349	DNA-binding transcription factor activity
LYZ33_02095	COG2213	PTS system mannitol-specific
LYZ33_02100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LYZ33_02110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LYZ33_02120	COG0561	phosphatase activity
LYZ33_02130	COG1914	H( )-stimulated, divalent metal cation uptake system
LYZ33_02140	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LYZ33_02145	COG1984	allophanate hydrolase subunit 2
LYZ33_02150	COG1414	Transcriptional regulator
LYZ33_02155	COG2755	lipolytic protein G-D-S-L family
LYZ33_02165	COG2329	Antibiotic biosynthesis monooxygenase
LYZ33_02170	COG0768	penicillin binding
LYZ33_02175	COG4989	oxidoreductase activity
LYZ33_02180	COG3711	transcriptional antiterminator
LYZ33_02185	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_02190	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_02195	COG1917	Cupin 2, conserved barrel domain protein
LYZ33_02200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LYZ33_02205	COG3871	stress protein (general stress protein 26)
LYZ33_02215	COG2814	Major facilitator Superfamily
LYZ33_02220	COG1522	sequence-specific DNA binding
LYZ33_02225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LYZ33_02225	COG0551	DNA topoisomerase type I activity
LYZ33_02230	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LYZ33_02235	COG3706	GGDEF domain
LYZ33_02240	COG5298	Protein conserved in bacteria
LYZ33_02245	COG1215	transferase activity, transferring glycosyl groups
LYZ33_02255	COG0531	amino acid
LYZ33_02260	COG0494	nUDIX hydrolase
LYZ33_02265	COG0028	Belongs to the TPP enzyme family
LYZ33_02300	COG1914	H( )-stimulated, divalent metal cation uptake system
LYZ33_02325	COG2217	Heavy metal translocating P-type atpase
LYZ33_02330	COG3729	General stress protein
LYZ33_02335	COG0662	Cupin 2, conserved barrel domain protein
LYZ33_02340	COG2329	Antibiotic biosynthesis monooxygenase
LYZ33_02345	COG3546	catalase activity
LYZ33_02350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LYZ33_02355	COG3290	protein histidine kinase activity
LYZ33_02360	COG4565	transcriptional regulatory protein
LYZ33_02365	COG1301	dicarboxylic acid transport
LYZ33_02370	COG0628	permease
LYZ33_02375	COG1131	(ABC) transporter
LYZ33_02380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LYZ33_02390	COG1960	acyl-CoA dehydrogenase activity
LYZ33_02405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LYZ33_02410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_02420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LYZ33_02425	COG0513	Belongs to the DEAD box helicase family
LYZ33_02430	COG3402	PFAM membrane-flanked domain
LYZ33_02435	COG3428	Bacterial PH domain
LYZ33_02440	COG0705	Rhomboid family
LYZ33_02450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LYZ33_02455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LYZ33_02460	COG0864	Transcriptional regulator
LYZ33_02465	COG2337	Toxic component of a toxin-antitoxin (TA) module
LYZ33_02470	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_02475	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_02480	COG2172	sigma factor antagonist activity
LYZ33_02485	COG2208	phosphoserine phosphatase activity
LYZ33_02490	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_02500	COG1191	sigma factor activity
LYZ33_02505	COG2208	phosphoserine phosphatase activity
LYZ33_02510	COG2183	response to ionizing radiation
LYZ33_02590	COG0477	Major facilitator Superfamily
LYZ33_02600	COG1764	response to oxidative stress
LYZ33_02605	COG1846	Transcriptional regulator
LYZ33_02615	COG1959	2 iron, 2 sulfur cluster binding
LYZ33_02620	COG2910	NAD(P)H-binding
LYZ33_02625	COG1278	Cold shock
LYZ33_02630	COG1329	Transcriptional regulator
LYZ33_02635	COG1794	racemase activity, acting on amino acids and derivatives
LYZ33_02650	COG1846	Transcriptional regulator
LYZ33_02650	COG0456	acetyltransferase
LYZ33_02655	COG2271	Major facilitator Superfamily
LYZ33_02660	COG3621	Patatin-like phospholipase
LYZ33_02675	COG0277	FAD linked oxidase domain protein
LYZ33_02695	COG0662	Cupin 2, conserved barrel domain protein
LYZ33_02700	COG2318	DinB family
LYZ33_02705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LYZ33_02730	COG0351	phosphomethylpyrimidine kinase
LYZ33_02745	COG1064	alcohol dehydrogenase
LYZ33_02750	COG0789	Transcriptional regulator
LYZ33_02760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LYZ33_02775	COG2814	Major facilitator Superfamily
LYZ33_02780	COG1309	transcriptional regulator
LYZ33_02785	COG5577	PFAM Coat F domain
LYZ33_02795	COG1063	alcohol dehydrogenase
LYZ33_02800	COG5577	PFAM Coat F domain
LYZ33_02815	COG4585	Histidine kinase
LYZ33_02820	COG2197	response regulator
LYZ33_02825	COG2409	Drug exporters of the RND superfamily
LYZ33_02830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LYZ33_02835	COG0488	(ABC) transporter
LYZ33_02840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LYZ33_02845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LYZ33_02855	COG2814	Major facilitator Superfamily
LYZ33_02860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LYZ33_02870	COG0730	response to heat
LYZ33_02875	COG0456	acetyltransferase
LYZ33_02880	COG0789	Transcriptional regulator
LYZ33_02880	COG4978	Transcriptional regulator
LYZ33_02885	COG0697	spore germination
LYZ33_02890	COG1051	belongs to the nudix hydrolase family
LYZ33_02895	COG0596	Alpha beta hydrolase
LYZ33_02900	COG0473	3-isopropylmalate dehydrogenase activity
LYZ33_02905	COG1802	Transcriptional regulator
LYZ33_02910	COG1819	glycosyl
LYZ33_02925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LYZ33_02935	COG1388	LysM domain
LYZ33_02940	COG2814	Major facilitator Superfamily
LYZ33_02945	COG2188	Transcriptional regulator
LYZ33_02950	COG2186	Transcriptional regulator
LYZ33_02955	COG2807	transmembrane transport
LYZ33_02960	COG2076	Multidrug Resistance protein
LYZ33_02965	COG2076	Multidrug Resistance protein
LYZ33_02970	COG1309	transcriptional regulator
LYZ33_02975	COG0531	amino acid
LYZ33_02985	COG3832	glyoxalase III activity
LYZ33_02990	COG0604	alcohol dehydrogenase
LYZ33_02995	COG2814	Major facilitator Superfamily
LYZ33_03035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LYZ33_03040	COG0802	atpase or kinase
LYZ33_03045	COG1214	PFAM Peptidase M22, glycoprotease
LYZ33_03050	COG0456	acetyltransferase
LYZ33_03055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LYZ33_03060	COG0488	(ABC) transporter
LYZ33_03075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LYZ33_03080	COG0805	protein transport
LYZ33_03090	COG1266	CAAX protease self-immunity
LYZ33_03110	COG0457	Tetratricopeptide repeat
LYZ33_03115	COG1063	alcohol dehydrogenase
LYZ33_03120	COG2211	Major facilitator Superfamily
LYZ33_03125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LYZ33_03135	COG1842	Phage shock protein A
LYZ33_03140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LYZ33_03145	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LYZ33_03150	COG4260	virion core protein, lumpy skin disease virus
LYZ33_03155	COG2755	lipolytic protein G-D-S-L family
LYZ33_03155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LYZ33_03165	COG1595	DNA-templated transcription, initiation
LYZ33_03170	COG1063	alcohol dehydrogenase
LYZ33_03175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LYZ33_03180	COG0823	Involved in the tonB-independent uptake of proteins
LYZ33_03195	COG2132	Multicopper oxidase
LYZ33_03200	COG1113	amino acid transport
LYZ33_03205	COG0714	Associated with various cellular activities
LYZ33_03210	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LYZ33_03215	COG1305	Transglutaminase-like
LYZ33_03255	COG2252	PERMEase
LYZ33_03260	COG3064	Membrane
LYZ33_03280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LYZ33_03285	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LYZ33_03290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LYZ33_03295	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LYZ33_03300	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LYZ33_03315	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LYZ33_03325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LYZ33_03330	COG0138	bifunctional purine biosynthesis protein purh
LYZ33_03335	COG0151	Belongs to the GarS family
LYZ33_03345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LYZ33_03350	COG1470	cell adhesion involved in biofilm formation
LYZ33_03355	COG4496	protein, YerC YecD
LYZ33_03360	COG0069	glutamate synthase activity
LYZ33_03370	COG0210	DNA helicase
LYZ33_03380	COG4851	CamS sex pheromone cAM373 precursor
LYZ33_03385	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LYZ33_03390	COG1285	pathogenesis
LYZ33_03395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LYZ33_03415	COG1309	transcriptional regulator
LYZ33_03420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LYZ33_03425	COG1597	lipid kinase activity
LYZ33_03430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LYZ33_03440	COG1131	(ABC) transporter
LYZ33_03460	COG5444	nuclease activity
LYZ33_03490	COG3546	catalase activity
LYZ33_03495	COG0454	-acetyltransferase
LYZ33_03505	COG2323	membrane
LYZ33_03510	COG2329	Antibiotic biosynthesis monooxygenase
LYZ33_03515	COG0346	lactoylglutathione lyase activity
LYZ33_03520	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_03525	COG5583	Uncharacterized small protein (DUF2292)
LYZ33_03530	COG0196	riboflavin kinase activity
LYZ33_03535	COG0670	Belongs to the BI1 family
LYZ33_03545	COG1846	Transcriptional regulator
LYZ33_03550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LYZ33_03560	COG2124	cytochrome p450
LYZ33_03560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LYZ33_03575	COG1131	(ABC) transporter
LYZ33_03620	COG4106	trans-aconitate 2-methyltransferase activity
LYZ33_03625	COG1368	sulfuric ester hydrolase activity
LYZ33_03630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LYZ33_03635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_03640	COG1442	glycosyl transferase family 8
LYZ33_03645	COG1216	Glycosyl transferase, family 2
LYZ33_03650	COG1442	glycosyl transferase family 8
LYZ33_03655	COG2223	nitrite transmembrane transporter activity
LYZ33_03660	COG0531	amino acid
LYZ33_03665	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_03670	COG0840	transmembrane signaling receptor activity
LYZ33_03675	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_03680	COG0457	Tetratricopeptide repeat
LYZ33_03680	COG0463	Glycosyl transferase, family 2
LYZ33_03685	COG0488	(ABC) transporter
LYZ33_03690	COG0789	Transcriptional regulator
LYZ33_03695	COG2814	Major facilitator Superfamily
LYZ33_03700	COG0488	(ABC) transporter
LYZ33_03705	COG0513	Belongs to the DEAD box helicase family
LYZ33_03715	COG2130	NADP-dependent
LYZ33_03730	COG3866	Pectate lyase
LYZ33_03735	COG0471	metal ion transport
LYZ33_03765	COG3290	protein histidine kinase activity
LYZ33_03770	COG4565	transcriptional regulatory protein
LYZ33_03775	COG3181	Tripartite tricarboxylate transporter family receptor
LYZ33_03780	COG2851	Citrate transporter
LYZ33_03785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LYZ33_03790	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LYZ33_03800	COG2258	MOSC domain
LYZ33_03820	COG0024	Methionine aminopeptidase
LYZ33_03825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LYZ33_03825	COG1263	PTS System
LYZ33_03835	COG1368	sulfuric ester hydrolase activity
LYZ33_03845	COG0071	Belongs to the small heat shock protein (HSP20) family
LYZ33_03860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LYZ33_03860	COG1263	PTS System
LYZ33_03865	COG0366	Alpha amylase catalytic
LYZ33_03870	COG2188	Transcriptional regulator
LYZ33_03875	COG0778	Nitroreductase
LYZ33_03890	COG0737	Belongs to the 5'-nucleotidase family
LYZ33_03895	COG0693	protein deglycase activity
LYZ33_03900	COG1609	Transcriptional regulator
LYZ33_03915	COG2814	Major facilitator Superfamily
LYZ33_03925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LYZ33_03930	COG4980	gas vesicle protein
LYZ33_03935	COG1295	ribonuclease BN
LYZ33_03940	COG0477	Major facilitator Superfamily
LYZ33_03945	COG0387	Pfam Sodium calcium exchanger
LYZ33_03955	COG0668	transmembrane transport
LYZ33_03960	COG0535	radical SAM domain protein
LYZ33_03970	COG0726	polysaccharide deacetylase
LYZ33_03975	COG2084	Dehydrogenase
LYZ33_03985	COG0598	Magnesium transport protein CorA
LYZ33_03990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LYZ33_03995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LYZ33_04005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LYZ33_04010	COG4637	Psort location Cytoplasmic, score
LYZ33_04015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LYZ33_04020	COG0022	dehydrogenase e1 component
LYZ33_04025	COG0508	dehydrogenase complex catalyzes the overall conversion of
LYZ33_04030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LYZ33_04035	COG3284	Transcriptional regulator
LYZ33_04045	COG1486	melibiose metabolic process
LYZ33_04050	COG1737	Transcriptional regulator
LYZ33_04055	COG1263	PTS System
LYZ33_04055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LYZ33_04060	COG1132	(ABC) transporter
LYZ33_04065	COG1132	(ABC) transporter
LYZ33_04070	COG2259	Doxx family
LYZ33_04075	COG2514	catechol 2,3-dioxygenase activity
LYZ33_04085	COG1695	Transcriptional regulator
LYZ33_04090	COG2249	NAD(P)H dehydrogenase (quinone) activity
LYZ33_04095	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LYZ33_04100	COG3848	Pyruvate phosphate dikinase
LYZ33_04100	COG0574	Belongs to the PEP-utilizing enzyme family
LYZ33_04105	COG2732	(Barnase) inhibitor
LYZ33_04110	COG2318	DinB family
LYZ33_04115	COG2814	Major facilitator Superfamily
LYZ33_04120	COG1846	Transcriptional regulator
LYZ33_04125	COG0392	lysyltransferase activity
LYZ33_04125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LYZ33_04130	COG0384	phenazine biosynthesis protein PhzF
LYZ33_04135	COG0778	Nitroreductase
LYZ33_04150	COG1090	epimerase
LYZ33_04165	COG2814	Major facilitator Superfamily
LYZ33_04175	COG3591	Belongs to the peptidase S1B family
LYZ33_04190	COG3103	Sh3 type 3 domain protein
LYZ33_04195	COG5658	integral membrane protein
LYZ33_04200	COG0596	Alpha beta hydrolase
LYZ33_04205	COG0463	Glycosyl transferase, family 2
LYZ33_04210	COG4485	Bacterial membrane protein, YfhO
LYZ33_04215	COG1988	membrane-bound metal-dependent
LYZ33_04220	COG1194	a g-specific adenine glycosylase
LYZ33_04230	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_04250	COG1132	(ABC) transporter
LYZ33_04255	COG4129	membrane
LYZ33_04265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LYZ33_04270	COG0735	belongs to the Fur family
LYZ33_04385	COG3340	Belongs to the peptidase S51 family
LYZ33_04395	COG0277	FAD linked oxidase domain protein
LYZ33_04405	COG0747	negative chemotaxis
LYZ33_04410	COG0601	transmembrane transport
LYZ33_04415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LYZ33_04420	COG0444	Belongs to the ABC transporter superfamily
LYZ33_04425	COG4608	Belongs to the ABC transporter superfamily
LYZ33_04430	COG0753	catalase activity
LYZ33_04440	COG1116	anion transmembrane transporter activity
LYZ33_04445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LYZ33_04450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LYZ33_04470	COG1476	TRANSCRIPTIONal
LYZ33_04480	COG3382	B3 4 domain protein
LYZ33_04485	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LYZ33_04495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LYZ33_04500	COG0789	Transcriptional regulator
LYZ33_04505	COG1664	Polymer-forming cytoskeletal
LYZ33_04510	COG1664	Polymer-forming cytoskeletal
LYZ33_04515	COG2766	serine protein kinase
LYZ33_04525	COG1846	Transcriptional regulator
LYZ33_04530	COG1566	PFAM secretion protein HlyD family protein
LYZ33_04535	COG2814	Major facilitator Superfamily
LYZ33_04540	COG0655	NAD(P)H dehydrogenase (quinone) activity
LYZ33_04555	COG1725	Transcriptional regulator
LYZ33_04560	COG1131	(ABC) transporter
LYZ33_04565	COG1131	(ABC) transporter
LYZ33_04570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LYZ33_04575	COG1278	Cold shock
LYZ33_04580	COG1464	Belongs to the NlpA lipoprotein family
LYZ33_04585	COG3706	GGDEF domain
LYZ33_04590	COG1823	symporter activity
LYZ33_04610	COG5577	PFAM Coat F domain
LYZ33_04615	COG0737	Belongs to the 5'-nucleotidase family
LYZ33_04615	COG4085	toxin activity
LYZ33_04615	COG1525	nuclease
LYZ33_04620	COG3764	Sortase (surface protein transpeptidase)
LYZ33_04625	COG0564	pseudouridine synthase activity
LYZ33_04635	COG0517	IMP dehydrogenase activity
LYZ33_04640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LYZ33_04645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LYZ33_04645	COG3153	acetyltransferase
LYZ33_04650	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LYZ33_04655	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LYZ33_04660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LYZ33_04670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LYZ33_04675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LYZ33_04680	COG4585	Histidine kinase
LYZ33_04680	COG2203	Gaf domain
LYZ33_04685	COG2197	response regulator
LYZ33_04690	COG0431	NADPH-dependent FMN reductase
LYZ33_04705	COG1388	LysM domain
LYZ33_04705	COG0791	NLP P60 protein
LYZ33_04710	COG1959	2 iron, 2 sulfur cluster binding
LYZ33_04720	COG2719	SpoVR family
LYZ33_04725	COG1785	Belongs to the alkaline phosphatase family
LYZ33_04730	COG1388	LysM domain
LYZ33_04730	COG0791	NLP P60 protein
LYZ33_04735	COG0583	DNA-binding transcription factor activity
LYZ33_04740	COG0372	Belongs to the citrate synthase family
LYZ33_04745	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_04750	COG0531	amino acid
LYZ33_04755	COG0733	neurotransmitter:sodium symporter activity
LYZ33_04770	COG1595	DNA-templated transcription, initiation
LYZ33_04775	COG0204	Acyl-transferase
LYZ33_04780	COG1253	flavin adenine dinucleotide binding
LYZ33_04785	COG0789	Transcriptional regulator
LYZ33_04790	COG0436	Aminotransferase
LYZ33_04795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LYZ33_04800	COG1253	flavin adenine dinucleotide binding
LYZ33_04805	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LYZ33_04810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LYZ33_04815	COG0584	glycerophosphoryl diester phosphodiesterase
LYZ33_04825	COG0668	transmembrane transport
LYZ33_04830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LYZ33_04835	COG0726	polysaccharide deacetylase
LYZ33_04840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LYZ33_04845	COG3226	Transcriptional regulator
LYZ33_04855	COG0589	response to stress
LYZ33_04860	COG1132	(ABC) transporter
LYZ33_04865	COG1132	(ABC) transporter
LYZ33_04870	COG0702	epimerase
LYZ33_04890	COG0189	ligase activity
LYZ33_04895	COG0189	ligase activity
LYZ33_04910	COG4335	DNA alkylation repair
LYZ33_04915	COG0561	phosphatase activity
LYZ33_04920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LYZ33_04930	COG0475	glutathione-regulated potassium exporter activity
LYZ33_04935	COG0490	domain, Protein
LYZ33_04945	COG1024	Enoyl-CoA hydratase
LYZ33_04955	COG4152	abc transporter atp-binding protein
LYZ33_04960	COG1668	transmembrane transport
LYZ33_04965	COG0420	3'-5' exonuclease activity
LYZ33_04970	COG4717	serine-type aminopeptidase activity
LYZ33_04985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LYZ33_05020	COG4980	gas vesicle protein
LYZ33_05035	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LYZ33_05040	COG0537	adenosine 5'-monophosphoramidase activity
LYZ33_05045	COG1131	(ABC) transporter
LYZ33_05050	COG4473	ABC transporter
LYZ33_05060	COG1473	amidohydrolase
LYZ33_05065	COG3069	C4-dicarboxylate transmembrane transporter activity
LYZ33_05070	COG2329	Antibiotic biosynthesis monooxygenase
LYZ33_05075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LYZ33_05085	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LYZ33_05090	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LYZ33_05095	COG1309	transcriptional regulator
LYZ33_05100	COG1511	domain protein
LYZ33_05105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LYZ33_05115	COG1363	Peptidase, m42
LYZ33_05120	COG1301	dicarboxylic acid transport
LYZ33_05130	COG1234	tRNA 3'-trailer cleavage
LYZ33_05135	COG0095	Lipoate-protein ligase
LYZ33_05140	COG0702	epimerase
LYZ33_05145	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_05155	COG0501	Belongs to the peptidase M48B family
LYZ33_05160	COG1404	Belongs to the peptidase S8 family
LYZ33_05165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LYZ33_05170	COG0406	alpha-ribazole phosphatase activity
LYZ33_05175	COG0183	Belongs to the thiolase family
LYZ33_05180	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_05185	COG1268	BioY protein
LYZ33_05190	COG0840	transmembrane signaling receptor activity
LYZ33_05195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LYZ33_05195	COG0723	plastoquinol--plastocyanin reductase activity
LYZ33_05200	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_05210	COG4903	ComK protein
LYZ33_05220	COG5646	InterPro IPR014922
LYZ33_05240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LYZ33_05255	COG0398	Pfam SNARE associated Golgi protein
LYZ33_05260	COG0681	Belongs to the peptidase S26 family
LYZ33_05265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LYZ33_05270	COG1846	Transcriptional regulator
LYZ33_05275	COG3180	Ammonia monooxygenase
LYZ33_05280	COG2814	Major facilitator Superfamily
LYZ33_05290	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LYZ33_05295	COG2323	membrane
LYZ33_05310	COG0420	3'-5' exonuclease activity
LYZ33_05315	COG0419	ATPase involved in DNA repair
LYZ33_05320	COG1403	HNH endonuclease
LYZ33_05360	COG0179	Fumarylacetoacetate (FAA) hydrolase
LYZ33_05375	COG0367	asparagine synthase
LYZ33_05380	COG1562	ergosterol biosynthetic process
LYZ33_05385	COG0534	Mate efflux family protein
LYZ33_05390	COG1917	Cupin 2, conserved barrel domain protein
LYZ33_05390	COG2207	Transcriptional regulator
LYZ33_05395	COG1609	Transcriptional regulator
LYZ33_05400	COG0673	inositol 2-dehydrogenase activity
LYZ33_05405	COG2318	DinB family
LYZ33_05410	COG1279	arginine transmembrane transporter activity
LYZ33_05415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LYZ33_05420	COG1357	PFAM Pentapeptide repeats (8 copies)
LYZ33_05425	COG2153	protein acetylation
LYZ33_05430	COG0646	methionine synthase
LYZ33_05430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LYZ33_05440	COG2996	Protein conserved in bacteria
LYZ33_05445	COG1744	ABC transporter substrate-binding protein PnrA-like
LYZ33_05450	COG0840	transmembrane signaling receptor activity
LYZ33_05460	COG1307	EDD domain protein, DegV family
LYZ33_05465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LYZ33_05485	COG0561	phosphatase activity
LYZ33_05490	COG1073	alpha beta
LYZ33_05495	COG2151	metal-sulfur cluster biosynthetic enzyme
LYZ33_05505	COG0277	FAD linked oxidase domain protein
LYZ33_05510	COG2271	Major facilitator Superfamily
LYZ33_05520	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LYZ33_05530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LYZ33_05535	COG0505	Belongs to the CarA family
LYZ33_05540	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LYZ33_05545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LYZ33_05560	COG2267	carboxylic ester hydrolase activity
LYZ33_05570	COG1744	ABC transporter substrate-binding protein PnrA-like
LYZ33_05585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LYZ33_05590	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LYZ33_05595	COG5504	Zn-dependent protease
LYZ33_05600	COG0444	Belongs to the ABC transporter superfamily
LYZ33_05605	COG4608	Belongs to the ABC transporter superfamily
LYZ33_05615	COG0601	transmembrane transport
LYZ33_05620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LYZ33_05630	COG0180	Tryptophanyl-tRNA synthetase
LYZ33_05635	COG4166	transmembrane transport
LYZ33_05640	COG0601	transmembrane transport
LYZ33_05645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LYZ33_05650	COG0444	Belongs to the ABC transporter superfamily
LYZ33_05655	COG4608	Belongs to the ABC transporter superfamily
LYZ33_05665	COG0456	acetyltransferase
LYZ33_05670	COG1393	Belongs to the ArsC family
LYZ33_05675	COG0861	Integral membrane protein TerC family
LYZ33_05685	COG4862	establishment of competence for transformation
LYZ33_05690	COG4469	Competence protein
LYZ33_05695	COG1164	Oligoendopeptidase f
LYZ33_05705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LYZ33_05710	COG2346	COG2346, Truncated hemoglobins
LYZ33_05715	COG0741	lytic transglycosylase activity
LYZ33_05720	COG4116	CYTH
LYZ33_05730	COG2357	RelA SpoT domain protein
LYZ33_05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LYZ33_05740	COG0564	pseudouridine synthase activity
LYZ33_05750	COG0475	glutathione-regulated potassium exporter activity
LYZ33_05750	COG0569	domain protein
LYZ33_05755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LYZ33_05760	COG0352	thiamine-phosphate diphosphorylase activity
LYZ33_05765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LYZ33_05770	COG2104	thiamine diphosphate biosynthetic process
LYZ33_05780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LYZ33_05785	COG0351	phosphomethylpyrimidine kinase
LYZ33_05790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LYZ33_05845	COG0210	DNA helicase
LYZ33_05865	COG1131	(ABC) transporter
LYZ33_05875	COG2153	protein acetylation
LYZ33_05885	COG2382	esterase
LYZ33_05890	COG0626	cystathionine gamma-synthase activity
LYZ33_05895	COG0626	cystathionine gamma-synthase activity
LYZ33_05910	COG5444	nuclease activity
LYZ33_05930	COG0135	phosphoribosylanthranilate isomerase activity
LYZ33_05975	COG2367	Beta-lactamase
LYZ33_05980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LYZ33_05990	COG1846	Transcriptional regulator
LYZ33_06000	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LYZ33_06005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LYZ33_06010	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LYZ33_06015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LYZ33_06015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LYZ33_06020	COG1447	Phosphotransferase system cellobiose-specific component IIA
LYZ33_06030	COG1349	DNA-binding transcription factor activity
LYZ33_06050	COG1285	pathogenesis
LYZ33_06060	COG2205	protein histidine kinase activity
LYZ33_06070	COG3383	formate dehydrogenase (NAD+) activity
LYZ33_06075	COG2427	Protein of unknown function (DUF1641)
LYZ33_06080	COG2124	cytochrome p450
LYZ33_06085	COG1819	glycosyl
LYZ33_06095	COG1587	Uroporphyrinogen-III synthase
LYZ33_06100	COG0390	transport system, permease component
LYZ33_06105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LYZ33_06110	COG0697	spore germination
LYZ33_06115	COG4297	protein containing double-stranded beta helix domain
LYZ33_06125	COG1252	NADH dehydrogenase
LYZ33_06135	COG2211	Major facilitator Superfamily
LYZ33_06140	COG1609	Transcriptional regulator
LYZ33_06145	COG0246	Mannitol dehydrogenase
LYZ33_06150	COG2721	sulfolactate sulfo-lyase activity
LYZ33_06155	COG0730	response to heat
LYZ33_06160	COG2318	DinB family
LYZ33_06165	COG0457	Tetratricopeptide repeat
LYZ33_06175	COG1388	LysM domain
LYZ33_06175	COG3409	Peptidoglycan-binding domain 1 protein
LYZ33_06175	COG5632	N-Acetylmuramoyl-L-alanine amidase
LYZ33_06185	COG4195	phage-related replication protein
LYZ33_06190	COG3546	catalase activity
LYZ33_06195	COG2856	Zn peptidase
LYZ33_06200	COG1396	sequence-specific DNA binding
LYZ33_06210	COG1522	sequence-specific DNA binding
LYZ33_06215	COG1484	DNA-dependent DNA replication
LYZ33_06235	COG1595	DNA-templated transcription, initiation
LYZ33_06240	COG3728	DNA packaging
LYZ33_06240	COG5484	DNA packaging
LYZ33_06245	COG1783	phage Terminase large subunit
LYZ33_06250	COG5518	Phage portal protein
LYZ33_06255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LYZ33_06260	COG4653	Phage capsid family
LYZ33_06310	COG3953	SLT domain
LYZ33_06310	COG5412	phage tail tape measure protein
LYZ33_06310	COG3953	SLT domain
LYZ33_06310	COG5412	phage tail tape measure protein
LYZ33_06310	COG3953	SLT domain
LYZ33_06310	COG5412	phage tail tape measure protein
LYZ33_06315	COG1652	LysM domain
LYZ33_06320	COG4193	domain, Protein
LYZ33_06330	COG3628	GPW Gp25 family protein
LYZ33_06335	COG3299	homolog of phage Mu protein gp47
LYZ33_06340	COG3778	Protein conserved in bacteria
LYZ33_06380	COG3409	Peptidoglycan-binding domain 1 protein
LYZ33_06380	COG5632	N-Acetylmuramoyl-L-alanine amidase
LYZ33_06400	COG0306	phosphate transporter
LYZ33_06405	COG1392	Phosphate transport regulator
LYZ33_06410	COG0531	amino acid
LYZ33_06415	COG0346	lactoylglutathione lyase activity
LYZ33_06420	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LYZ33_06425	COG0463	Glycosyl transferase, family 2
LYZ33_06435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LYZ33_06440	COG0477	Major facilitator Superfamily
LYZ33_06445	COG2362	D-Aminopeptidase
LYZ33_06450	COG0601	transmembrane transport
LYZ33_06455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LYZ33_06460	COG0444	Belongs to the ABC transporter superfamily
LYZ33_06465	COG4166	transmembrane transport
LYZ33_06470	COG1619	proteins homologs of microcin C7 resistance protein MccF
LYZ33_06475	COG4948	Mandelate Racemase Muconate Lactonizing
LYZ33_06480	COG0791	NLP P60 protein
LYZ33_06485	COG4608	Belongs to the ABC transporter superfamily
LYZ33_06490	COG2706	6-phosphogluconolactonase activity
LYZ33_06495	COG1834	amidinotransferase
LYZ33_06500	COG1607	acyl-coa hydrolase
LYZ33_06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LYZ33_06510	COG2076	Multidrug Resistance protein
LYZ33_06515	COG2076	Multidrug Resistance protein
LYZ33_06520	COG0788	formyltetrahydrofolate deformylase activity
LYZ33_06525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LYZ33_06535	COG1764	response to oxidative stress
LYZ33_06540	COG1846	Transcriptional regulator
LYZ33_06545	COG1764	response to oxidative stress
LYZ33_06560	COG0457	Tetratricopeptide repeat
LYZ33_06560	COG0463	Glycosyl transferase, family 2
LYZ33_06570	COG2814	Major facilitator Superfamily
LYZ33_06575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LYZ33_06585	COG1404	Belongs to the peptidase S8 family
LYZ33_06590	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_06595	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LYZ33_06600	COG1122	ATPase activity
LYZ33_06605	COG4721	ABC-type cobalt transport system, permease component
LYZ33_06620	COG2239	Acts as a magnesium transporter
LYZ33_06625	COG0789	Transcriptional regulator
LYZ33_06640	COG1846	Transcriptional regulator
LYZ33_06645	COG0726	polysaccharide deacetylase
LYZ33_06650	COG1793	dna ligase
LYZ33_06650	COG3285	dna ligase
LYZ33_06655	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LYZ33_06660	COG0586	Pfam SNARE associated Golgi protein
LYZ33_06670	COG1191	sigma factor activity
LYZ33_06695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LYZ33_06700	COG2323	membrane
LYZ33_06710	COG3594	Acyltransferase
LYZ33_06715	COG5002	protein histidine kinase activity
LYZ33_06720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LYZ33_06740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LYZ33_06745	COG0436	Aminotransferase
LYZ33_06775	COG3852	Histidine kinase
LYZ33_06780	COG1846	Transcriptional regulator
LYZ33_06785	COG1360	Flagellar Motor Protein
LYZ33_06790	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LYZ33_06795	COG0542	response to heat
LYZ33_06800	COG3949	Membrane
LYZ33_06815	COG0720	synthase
LYZ33_06820	COG0602	queuosine metabolic process
LYZ33_06870	COG4873	Protein conserved in bacteria
LYZ33_06880	COG3773	Cell wall hydrolase
LYZ33_06885	COG2244	polysaccharide biosynthetic process
LYZ33_06890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_06895	COG2217	Heavy metal translocating P-type atpase
LYZ33_06900	COG0006	proline dipeptidase activity
LYZ33_06905	COG1609	Transcriptional regulator
LYZ33_06910	COG3711	transcriptional antiterminator
LYZ33_06915	COG1263	PTS System
LYZ33_06915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LYZ33_06915	COG2190	(PTS) system
LYZ33_06920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LYZ33_06925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LYZ33_06935	COG1533	DNA photolyase activity
LYZ33_06940	COG0840	transmembrane signaling receptor activity
LYZ33_06945	COG2084	Dehydrogenase
LYZ33_06960	COG2340	Cysteine-rich secretory protein family
LYZ33_06965	COG0768	penicillin binding
LYZ33_06970	COG4191	Histidine kinase
LYZ33_06975	COG0436	Aminotransferase
LYZ33_06985	COG0784	Response regulator, receiver
LYZ33_06985	COG0835	chemotaxis
LYZ33_06995	COG2814	Major facilitator Superfamily
LYZ33_07000	COG1376	ErfK ybiS ycfS ynhG family protein
LYZ33_07005	COG1408	metallophosphoesterase
LYZ33_07010	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_07020	COG2200	EAL domain
LYZ33_07025	COG4703	Protein of unknown function (DUF1797)
LYZ33_07030	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LYZ33_07040	COG0517	IMP dehydrogenase activity
LYZ33_07045	COG0583	DNA-binding transcription factor activity
LYZ33_07050	COG0716	FMN binding
LYZ33_07060	COG0716	FMN binding
LYZ33_07080	COG0668	transmembrane transport
LYZ33_07085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_07105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LYZ33_07110	COG0303	'Molybdopterin
LYZ33_07115	COG1763	Mo-molybdopterin cofactor biosynthetic process
LYZ33_07120	COG0314	molybdopterin synthase activity
LYZ33_07125	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LYZ33_07135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LYZ33_07140	COG1136	(ABC) transporter
LYZ33_07145	COG0577	efflux transmembrane transporter activity
LYZ33_07150	COG1349	DNA-binding transcription factor activity
LYZ33_07155	COG1105	Belongs to the carbohydrate kinase PfkB family
LYZ33_07160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LYZ33_07160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LYZ33_07160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LYZ33_07165	COG0681	Belongs to the peptidase S26 family
LYZ33_07175	COG0488	(ABC) transporter
LYZ33_07180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LYZ33_07185	COG2309	aminopeptidase activity
LYZ33_07195	COG1077	Cell shape determining protein MreB Mrl
LYZ33_07200	COG2002	toxin-antitoxin pair type II binding
LYZ33_07205	COG3852	Histidine kinase
LYZ33_07210	COG2105	PFAM AIG2 family protein
LYZ33_07210	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LYZ33_07215	COG0569	domain protein
LYZ33_07225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LYZ33_07235	COG0561	phosphatase activity
LYZ33_07240	COG0242	peptide deformylase activity
LYZ33_07250	COG0497	DNA recombination
LYZ33_07255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LYZ33_07255	COG2070	2-Nitropropane dioxygenase
LYZ33_07260	COG4221	oxidoreductase activity
LYZ33_07260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_07260	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_07260	COG3321	synthase
LYZ33_07265	COG4221	oxidoreductase activity
LYZ33_07265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_07265	COG3321	synthase
LYZ33_07265	COG0300	oxidoreductase activity
LYZ33_07270	COG4221	oxidoreductase activity
LYZ33_07270	COG3321	synthase
LYZ33_07270	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_07270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_07275	COG0300	oxidoreductase activity
LYZ33_07275	COG3321	synthase
LYZ33_07275	COG4221	oxidoreductase activity
LYZ33_07280	COG3321	synthase
LYZ33_07280	COG0300	oxidoreductase activity
LYZ33_07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_07280	COG4221	oxidoreductase activity
LYZ33_07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_07285	COG0300	oxidoreductase activity
LYZ33_07285	COG4221	oxidoreductase activity
LYZ33_07285	COG3321	synthase
LYZ33_07290	COG4221	oxidoreductase activity
LYZ33_07290	COG3321	synthase
LYZ33_07290	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_07290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_07295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LYZ33_07300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LYZ33_07305	COG0022	dehydrogenase e1 component
LYZ33_07310	COG0508	dehydrogenase complex catalyzes the overall conversion of
LYZ33_07315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LYZ33_07320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_07335	COG1982	Orn Lys Arg decarboxylase major
LYZ33_07355	COG0483	inositol monophosphate 1-phosphatase activity
LYZ33_07365	COG3227	Zinc metalloprotease (Elastase)
LYZ33_07370	COG1595	DNA-templated transcription, initiation
LYZ33_07390	COG1217	gtp-binding protein TYPA
LYZ33_07400	COG4896	Protein conserved in bacteria
LYZ33_07410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LYZ33_07415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LYZ33_07420	COG2066	Belongs to the glutaminase family
LYZ33_07430	COG0772	Belongs to the SEDS family
LYZ33_07435	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LYZ33_07450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LYZ33_07450	COG2010	Cytochrome c
LYZ33_07455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LYZ33_07460	COG1845	cytochrome c oxidase, subunit III
LYZ33_07465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LYZ33_07470	COG3336	cytochrome c oxidase
LYZ33_07480	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LYZ33_07485	COG2340	Cysteine-rich secretory protein family
LYZ33_07500	COG3679	Belongs to the UPF0342 family
LYZ33_07515	COG0742	ribosomal rna small subunit methyltransferase
LYZ33_07525	COG3314	Sporulation integral membrane protein YlbJ
LYZ33_07530	COG1752	Esterase of the alpha-beta hydrolase superfamily
LYZ33_07535	COG3480	Lon protease (S16) C-terminal proteolytic domain
LYZ33_07545	COG1399	metal-binding, possibly nucleic acid-binding protein
LYZ33_07565	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LYZ33_07585	COG4839	cell division protein FtsL
LYZ33_07590	COG0768	penicillin binding
LYZ33_07595	COG0768	penicillin binding
LYZ33_07615	COG0772	Belongs to the SEDS family
LYZ33_07630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LYZ33_07635	COG0849	cell division
LYZ33_07640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LYZ33_07645	COG1404	Belongs to the peptidase S8 family
LYZ33_07645	COG4412	M6 family metalloprotease domain protein
LYZ33_07655	COG1191	sigma factor activity
LYZ33_07660	COG1191	sigma factor activity
LYZ33_07665	COG1119	ATPase activity
LYZ33_07670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LYZ33_07675	COG1873	PFAM PRC-barrel domain
LYZ33_07680	COG1496	oxidoreductase activity
LYZ33_07685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LYZ33_07695	COG0762	integral membrane protein
LYZ33_07700	COG2302	S4 RNA-binding domain
LYZ33_07705	COG3599	regulation of cell shape
LYZ33_07710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LYZ33_07715	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LYZ33_07725	COG0564	pseudouridine synthase activity
LYZ33_07735	COG2233	PERMEase
LYZ33_07745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LYZ33_07750	COG0505	Belongs to the CarA family
LYZ33_07755	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LYZ33_07770	COG0284	orotidine-5'-phosphate decarboxylase activity
LYZ33_07775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LYZ33_07785	COG0306	phosphate transporter
LYZ33_07800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LYZ33_07805	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LYZ33_07810	COG1648	precorrin-2 dehydrogenase activity
LYZ33_07820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LYZ33_07825	COG1561	YicC-like family, N-terminal region
LYZ33_07835	COG0194	GDP metabolic process
LYZ33_07845	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LYZ33_07850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LYZ33_07855	COG0242	peptide deformylase activity
LYZ33_07865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LYZ33_07865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LYZ33_07875	COG0631	protein serine/threonine phosphatase activity
LYZ33_07880	COG0515	serine threonine protein kinase
LYZ33_07880	COG2815	serine threonine protein kinase
LYZ33_07890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LYZ33_07895	COG1564	THIamine pyrophosphokinase
LYZ33_07910	COG1302	Protein conserved in bacteria
LYZ33_07915	COG1461	Dihydroxyacetone kinase
LYZ33_07920	COG1760	l-serine dehydratase
LYZ33_07925	COG1760	l-serine dehydratase
LYZ33_07930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LYZ33_07945	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LYZ33_07950	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_07965	COG1196	nuclear chromosome segregation
LYZ33_07970	COG0552	protein localization to endoplasmic reticulum
LYZ33_07985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LYZ33_07995	COG1837	Belongs to the UPF0109 family
LYZ33_08020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LYZ33_08035	COG2257	FlhB HrpN YscU SpaS Family
LYZ33_08045	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LYZ33_08050	COG0758	DNA mediated transformation
LYZ33_08055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LYZ33_08065	COG4974	Belongs to the 'phage' integrase family
LYZ33_08085	COG1815	bacterial-type flagellum-dependent cell motility
LYZ33_08090	COG1558	bacterial-type flagellum-dependent cell motility
LYZ33_08095	COG1677	Flagellar hook-basal body complex protein FliE
LYZ33_08100	COG1766	The M ring may be actively involved in energy transduction
LYZ33_08105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LYZ33_08110	COG1317	bacterial-type flagellum organization
LYZ33_08115	COG1157	protein secretion by the type III secretion system
LYZ33_08120	COG2882	bacterial-type flagellum organization
LYZ33_08125	COG3334	PFAM MgtE intracellular
LYZ33_08130	COG3144	bacterial-type flagellum assembly
LYZ33_08135	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LYZ33_08140	COG4786	Flagellar basal body rod
LYZ33_08145	COG1582	Flagellar protein (FlbD)
LYZ33_08150	COG1580	Controls the rotational direction of flagella during chemotaxis
LYZ33_08155	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LYZ33_08160	COG1776	CheC inhibitor of MCP methylation
LYZ33_08160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LYZ33_08165	COG2201	protein-glutamate methylesterase activity
LYZ33_08170	COG3190	flagellar
LYZ33_08175	COG1338	Plays a role in the flagellum-specific transport system
LYZ33_08180	COG1987	bacterial-type flagellum assembly
LYZ33_08185	COG1684	flagellar biosynthetic protein fliR
LYZ33_08190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LYZ33_08195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LYZ33_08200	COG1419	protein localization to endoplasmic reticulum
LYZ33_08205	COG0455	bacterial-type flagellum organization
LYZ33_08210	COG2201	protein-glutamate methylesterase activity
LYZ33_08215	COG2198	Histidine kinase
LYZ33_08215	COG0643	Histidine kinase
LYZ33_08220	COG0835	chemotaxis
LYZ33_08225	COG1776	CheC inhibitor of MCP methylation
LYZ33_08235	COG1191	sigma factor activity
LYZ33_08265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LYZ33_08270	COG4589	Belongs to the CDS family
LYZ33_08280	COG0750	zinc metalloprotease
LYZ33_08300	COG0195	Participates in both transcription termination and antitermination
LYZ33_08305	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LYZ33_08310	COG1358	cellular component organization or biogenesis
LYZ33_08320	COG1550	Protein conserved in bacteria
LYZ33_08335	COG0196	riboflavin kinase activity
LYZ33_08350	COG0726	polysaccharide deacetylase
LYZ33_08355	COG0612	Peptidase, M16
LYZ33_08360	COG1873	PFAM PRC-barrel domain
LYZ33_08365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LYZ33_08370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LYZ33_08375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LYZ33_08380	COG0527	aspartate kinase activity
LYZ33_08390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LYZ33_08395	COG0740	serine-type endopeptidase activity
LYZ33_08405	COG1674	ftsk spoiiie
LYZ33_08405	COG4980	gas vesicle protein
LYZ33_08410	COG2188	Transcriptional regulator
LYZ33_08415	COG2814	Major facilitator Superfamily
LYZ33_08420	COG1846	Transcriptional regulator
LYZ33_08425	COG1033	growth of symbiont in host cell
LYZ33_08425	COG2409	Drug exporters of the RND superfamily
LYZ33_08430	COG0612	Peptidase, M16
LYZ33_08435	COG0612	Peptidase, M16
LYZ33_08440	COG0300	oxidoreductase activity
LYZ33_08455	COG1426	Protein conserved in bacteria
LYZ33_08460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LYZ33_08475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LYZ33_08485	COG1692	metallophosphoesterase
LYZ33_08490	COG2359	stage V sporulation protein S
LYZ33_08510	COG4550	Control of competence regulator ComK, YlbF/YmcA
LYZ33_08555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_08560	COG3425	synthase
LYZ33_08565	COG1024	Enoyl-CoA hydratase
LYZ33_08570	COG1024	Enoyl-CoA hydratase
LYZ33_08575	COG3321	synthase
LYZ33_08575	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_08575	COG0300	oxidoreductase activity
LYZ33_08575	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_08575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_08580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_08580	COG3321	synthase
LYZ33_08580	COG0300	oxidoreductase activity
LYZ33_08580	COG4221	oxidoreductase activity
LYZ33_08585	COG3321	synthase
LYZ33_08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_08585	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_08585	COG3321	synthase
LYZ33_08585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_08585	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_08585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_08590	COG3321	synthase
LYZ33_08590	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_08590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_08590	COG4221	oxidoreductase activity
LYZ33_08595	COG3321	synthase
LYZ33_08595	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LYZ33_08595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LYZ33_08595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_08600	COG2124	cytochrome p450
LYZ33_08605	COG3209	COG3209 Rhs family protein
LYZ33_08610	COG3619	membrane
LYZ33_08620	COG1404	Belongs to the peptidase S8 family
LYZ33_08630	COG4195	phage-related replication protein
LYZ33_08635	COG1764	response to oxidative stress
LYZ33_08645	COG2076	Multidrug Resistance protein
LYZ33_08685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LYZ33_08690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LYZ33_08695	COG4112	unkown
LYZ33_08700	COG0860	N-Acetylmuramoyl-L-alanine amidase
LYZ33_08705	COG0464	growth
LYZ33_08710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LYZ33_08715	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LYZ33_08720	COG0789	Transcriptional regulator
LYZ33_08725	COG0174	glutamine synthetase
LYZ33_08910	COG5280	Phage tail tape measure protein TP901
LYZ33_08910	COG3953	SLT domain
LYZ33_08920	COG1705	Flagellar rod assembly protein muramidase FlgJ
LYZ33_08925	COG5434	Belongs to the glycosyl hydrolase 28 family
LYZ33_08970	COG5444	nuclease activity
LYZ33_08975	COG0457	Tetratricopeptide repeat
LYZ33_08990	COG2211	Major facilitator Superfamily
LYZ33_08995	COG3507	Belongs to the glycosyl hydrolase 43 family
LYZ33_09010	COG1070	Carbohydrate kinase
LYZ33_09015	COG0574	Belongs to the PEP-utilizing enzyme family
LYZ33_09015	COG3848	Pyruvate phosphate dikinase
LYZ33_09030	COG1064	alcohol dehydrogenase
LYZ33_09055	COG0456	acetyltransferase
LYZ33_09075	COG3397	chitin binding
LYZ33_09095	COG5434	Belongs to the glycosyl hydrolase 28 family
LYZ33_09100	COG0756	dUTP diphosphatase activity
LYZ33_09105	COG4195	phage-related replication protein
LYZ33_09140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LYZ33_09150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LYZ33_09170	COG0785	Cytochrome C biogenesis protein
LYZ33_09175	COG2201	protein-glutamate methylesterase activity
LYZ33_09180	COG4846	Membrane protein involved in cytochrome C biogenesis
LYZ33_09190	COG0071	Belongs to the small heat shock protein (HSP20) family
LYZ33_09205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LYZ33_09210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_09230	COG0824	Thioesterase
LYZ33_09240	COG4841	protein insertion into membrane
LYZ33_09250	COG1832	CoA-binding protein
LYZ33_09255	COG0187	DNA topoisomerase II activity
LYZ33_09260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LYZ33_09270	COG1115	amino acid carrier protein
LYZ33_09280	COG1063	alcohol dehydrogenase
LYZ33_09285	COG0800	Aldolase
LYZ33_09290	COG1312	Catalyzes the dehydration of D-mannonate
LYZ33_09295	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_09300	COG1609	Transcriptional regulator
LYZ33_09305	COG2271	Major facilitator Superfamily
LYZ33_09340	COG2205	protein histidine kinase activity
LYZ33_09345	COG0745	RESPONSE REGULATOR receiver
LYZ33_09355	COG3507	Belongs to the glycosyl hydrolase 43 family
LYZ33_09380	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_09385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LYZ33_09390	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LYZ33_09395	COG2610	gluconate transmembrane transporter activity
LYZ33_09400	COG2124	cytochrome p450
LYZ33_09420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LYZ33_09430	COG2246	polysaccharide biosynthetic process
LYZ33_09435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LYZ33_09440	COG0586	Pfam SNARE associated Golgi protein
LYZ33_09445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LYZ33_09450	COG1024	Enoyl-CoA hydratase
LYZ33_09455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LYZ33_09460	COG0511	ligase activity, forming carbon-carbon bonds
LYZ33_09465	COG0439	Biotin carboxylase
LYZ33_09470	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_09475	COG1960	acyl-CoA dehydrogenase activity
LYZ33_09480	COG1649	PFAM Uncharacterised BCR, COG1649
LYZ33_09490	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LYZ33_09490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_09495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_09500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_09505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_09510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_09515	COG2027	D-alanyl-D-alanine carboxypeptidase
LYZ33_09520	COG2017	converts alpha-aldose to the beta-anomer
LYZ33_09525	COG0534	Mate efflux family protein
LYZ33_09540	COG0582	viral genome integration into host DNA
LYZ33_09545	COG0166	Belongs to the GPI family
LYZ33_09550	COG0405	Gamma-glutamyltransferase
LYZ33_09555	COG2814	Major facilitator Superfamily
LYZ33_09560	COG0640	Transcriptional regulator
LYZ33_09565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LYZ33_09575	COG0604	alcohol dehydrogenase
LYZ33_09585	COG0493	'glutamate synthase
LYZ33_09590	COG0067	glutamate synthase
LYZ33_09590	COG0069	glutamate synthase activity
LYZ33_09590	COG0070	glutamate synthase
LYZ33_09595	COG0583	DNA-binding transcription factor activity
LYZ33_09600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LYZ33_09615	COG0300	oxidoreductase activity
LYZ33_09620	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LYZ33_09630	COG2814	Major facilitator Superfamily
LYZ33_09635	COG1070	Carbohydrate kinase
LYZ33_09640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LYZ33_09645	COG0243	molybdopterin cofactor binding
LYZ33_09665	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_09670	COG1733	regulation of RNA biosynthetic process
LYZ33_09675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LYZ33_09680	COG0662	Cupin 2, conserved barrel domain protein
LYZ33_09680	COG2207	Transcriptional regulator
LYZ33_09685	COG1309	transcriptional regulator
LYZ33_09690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LYZ33_09700	COG0640	Transcriptional regulator
LYZ33_09705	COG0741	lytic transglycosylase activity
LYZ33_09710	COG2322	membrane
LYZ33_09725	COG1619	proteins homologs of microcin C7 resistance protein MccF
LYZ33_09735	COG1388	LysM domain
LYZ33_09735	COG3584	3D domain protein
LYZ33_09740	COG0514	ATP-dependent DNA helicase (RecQ)
LYZ33_09750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LYZ33_09755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LYZ33_09770	COG0071	Belongs to the small heat shock protein (HSP20) family
LYZ33_09800	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_09805	COG1657	PFAM Prenyltransferase squalene oxidase
LYZ33_09810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LYZ33_09815	COG0733	neurotransmitter:sodium symporter activity
LYZ33_09820	COG0385	Bile acid
LYZ33_09825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LYZ33_09830	COG0508	dehydrogenase complex catalyzes the overall conversion of
LYZ33_09840	COG4548	von Willebrand factor, type A
LYZ33_09845	COG0714	Associated with various cellular activities
LYZ33_09850	COG2032	superoxide dismutase activity
LYZ33_09855	COG1388	LysM domain
LYZ33_09855	COG0791	NLP P60 protein
LYZ33_09860	COG1819	glycosyl
LYZ33_09865	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LYZ33_09870	COG0534	Mate efflux family protein
LYZ33_09875	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_09880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LYZ33_09885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LYZ33_09895	COG2962	Rard protein
LYZ33_09910	COG1942	4-Oxalocrotonate Tautomerase
LYZ33_09920	COG1733	regulation of RNA biosynthetic process
LYZ33_09925	COG0778	Nitroreductase
LYZ33_09930	COG0400	carboxylic ester hydrolase activity
LYZ33_09935	COG0346	lactoylglutathione lyase activity
LYZ33_09945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LYZ33_09955	COG2723	6-phospho-beta-galactosidase activity
LYZ33_09960	COG2188	Transcriptional regulator
LYZ33_09965	COG3409	Peptidoglycan-binding domain 1 protein
LYZ33_09965	COG0793	Belongs to the peptidase S41A family
LYZ33_09970	COG2226	methyltransferase
LYZ33_09980	COG1876	peptidase activity
LYZ33_10000	COG0671	phosphoesterase, PA-phosphatase related
LYZ33_10035	COG1509	lysine 2,3-aminomutase activity
LYZ33_10040	COG0456	acetyltransferase
LYZ33_10045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LYZ33_10050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LYZ33_10055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LYZ33_10060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LYZ33_10075	COG0456	acetyltransferase
LYZ33_10080	COG0463	Glycosyl transferase, family 2
LYZ33_10095	COG4641	Protein conserved in bacteria
LYZ33_10105	COG1086	Polysaccharide biosynthesis protein
LYZ33_10135	COG1388	LysM domain
LYZ33_10140	COG0457	Tetratricopeptide repeat
LYZ33_10165	COG5444	nuclease activity
LYZ33_10170	COG4282	regulation of fungal-type cell wall biogenesis
LYZ33_10175	COG1525	nuclease
LYZ33_10205	COG1846	Transcriptional regulator
LYZ33_10210	COG4698	Protein conserved in bacteria
LYZ33_10215	COG2755	lipolytic protein G-D-S-L family
LYZ33_10220	COG1999	signal sequence binding
LYZ33_10230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LYZ33_10235	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LYZ33_10240	COG1272	protein, Hemolysin III
LYZ33_10245	COG0204	Acyl-transferase
LYZ33_10250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LYZ33_10265	COG2521	methyltransferase
LYZ33_10265	COG2136	Putative SAM-dependent methyltransferase
LYZ33_10280	COG1413	lyase activity
LYZ33_10285	COG1418	mRNA catabolic process
LYZ33_10290	COG0386	Belongs to the glutathione peroxidase family
LYZ33_10300	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LYZ33_10310	COG1278	Cold shock
LYZ33_10330	COG0328	RNA-DNA hybrid ribonuclease activity
LYZ33_10335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LYZ33_10340	COG0328	RNA-DNA hybrid ribonuclease activity
LYZ33_10350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LYZ33_10365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LYZ33_10375	COG1755	Isoprenylcysteine carboxyl methyltransferase
LYZ33_10380	COG3424	synthase
LYZ33_10405	COG1335	isochorismatase
LYZ33_10415	COG2233	PERMEase
LYZ33_10425	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LYZ33_10430	COG1199	ATP-dependent helicase activity
LYZ33_10445	COG0116	Belongs to the methyltransferase superfamily
LYZ33_10475	COG3359	exonuclease
LYZ33_10480	COG1111	helicase
LYZ33_10480	COG1205	dead DEAH box helicase
LYZ33_10485	COG2190	(PTS) system
LYZ33_10490	COG0071	Belongs to the small heat shock protein (HSP20) family
LYZ33_10530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LYZ33_10530	COG4499	WXG100 protein secretion system (Wss), protein YukC
LYZ33_10540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LYZ33_10545	COG3935	DnaD domain protein
LYZ33_10555	COG0436	Aminotransferase
LYZ33_10560	COG5353	protein conserved in bacteria
LYZ33_10570	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LYZ33_10570	COG1199	ATP-dependent helicase activity
LYZ33_10600	COG0438	transferase activity, transferring glycosyl groups
LYZ33_10605	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LYZ33_10620	COG1694	Mazg nucleotide pyrophosphohydrolase
LYZ33_10625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LYZ33_10630	COG2140	Oxalate decarboxylase
LYZ33_10640	COG4347	Protein of unknown function (DUF1405)
LYZ33_10645	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LYZ33_10645	COG2010	Cytochrome c
LYZ33_10650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LYZ33_10655	COG0723	plastoquinol--plastocyanin reductase activity
LYZ33_10670	COG0457	Tetratricopeptide repeat
LYZ33_10680	COG0287	Prephenate dehydrogenase
LYZ33_10715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LYZ33_10720	COG4401	Chorismate mutase type I
LYZ33_10735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LYZ33_10740	COG0105	UTP biosynthetic process
LYZ33_10745	COG0142	geranyltranstransferase activity
LYZ33_10755	COG0142	geranyltranstransferase activity
LYZ33_10770	COG0776	regulation of translation
LYZ33_10775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LYZ33_10815	COG0539	negative regulation of cytoplasmic translation
LYZ33_10830	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LYZ33_10835	COG2959	enzyme of heme biosynthesis
LYZ33_10840	COG3409	Peptidoglycan-binding domain 1 protein
LYZ33_10840	COG3773	Cell wall hydrolase
LYZ33_10845	COG2339	peptidase activity
LYZ33_10850	COG0492	ferredoxin-NADP+ reductase activity
LYZ33_10855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LYZ33_10860	COG4862	establishment of competence for transformation
LYZ33_10865	COG1408	metallophosphoesterase
LYZ33_10875	COG1388	LysM domain
LYZ33_10880	COG1266	CAAX protease self-immunity
LYZ33_10885	COG0514	ATP-dependent DNA helicase (RecQ)
LYZ33_10890	COG4955	Helix-turn-helix domain
LYZ33_10895	COG1141	Ferredoxin
LYZ33_10900	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LYZ33_10905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LYZ33_10915	COG1595	DNA-templated transcription, initiation
LYZ33_10920	COG5002	protein histidine kinase activity
LYZ33_10925	COG0745	RESPONSE REGULATOR receiver
LYZ33_10930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LYZ33_10935	COG1333	cytochrome c biogenesis protein
LYZ33_10940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_10945	COG1187	pseudouridine synthase activity
LYZ33_10950	COG0700	Nucleoside recognition
LYZ33_10955	COG2715	membrane protein required for spore maturation
LYZ33_10960	COG1686	Belongs to the peptidase S11 family
LYZ33_10985	COG1547	Domain of unknown function (DUF309)
LYZ33_10990	COG0456	acetyltransferase
LYZ33_11005	COG0307	riboflavin synthase, alpha
LYZ33_11010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LYZ33_11010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LYZ33_11020	COG0681	Belongs to the peptidase S26 family
LYZ33_11030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LYZ33_11035	COG4086	secreted protein
LYZ33_11040	COG0019	diaminopimelate decarboxylase activity
LYZ33_11045	COG0697	spore germination
LYZ33_11060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LYZ33_11080	COG1191	sigma factor activity
LYZ33_11090	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_11095	COG1686	Belongs to the peptidase S11 family
LYZ33_11100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LYZ33_11105	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LYZ33_11110	COG4974	Belongs to the 'phage' integrase family
LYZ33_11120	COG0735	belongs to the Fur family
LYZ33_11125	COG1300	Membrane
LYZ33_11140	COG0281	malic enzyme
LYZ33_11145	COG1757	Na H antiporter
LYZ33_11150	COG1027	Aspartate ammonia-lyase
LYZ33_11155	COG0252	asparaginase activity
LYZ33_11160	COG1396	sequence-specific DNA binding
LYZ33_11165	COG1379	DNA repair
LYZ33_11170	COG0494	nUDIX hydrolase
LYZ33_11180	COG0667	Aldo Keto reductase
LYZ33_11190	COG1073	alpha beta
LYZ33_11200	COG4918	Iron-sulphur cluster biosynthesis
LYZ33_11205	COG0456	acetyltransferase
LYZ33_11205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LYZ33_11210	COG2329	Antibiotic biosynthesis monooxygenase
LYZ33_11215	COG0456	acetyltransferase
LYZ33_11220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LYZ33_11235	COG0628	permease
LYZ33_11245	COG0346	lactoylglutathione lyase activity
LYZ33_11255	COG3048	D-serine ammonia-lyase activity
LYZ33_11260	COG0300	oxidoreductase activity
LYZ33_11265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LYZ33_11270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LYZ33_11275	COG1024	Enoyl-CoA hydratase
LYZ33_11280	COG3425	synthase
LYZ33_11285	COG2124	cytochrome p450
LYZ33_11290	COG3321	synthase
LYZ33_11290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_11290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_11290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_11290	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11295	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_11295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_11295	COG3321	synthase
LYZ33_11295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_11300	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_11300	COG0300	oxidoreductase activity
LYZ33_11300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_11300	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11300	COG3321	synthase
LYZ33_11310	COG3321	synthase
LYZ33_11310	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_11310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_11310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_11315	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11315	COG3321	synthase
LYZ33_11315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_11315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_11315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_11320	COG0300	oxidoreductase activity
LYZ33_11320	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_11320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_11320	COG3321	synthase
LYZ33_11320	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11325	COG3321	synthase
LYZ33_11325	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_11325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_11325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LYZ33_11330	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_11335	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_11350	COG2070	2-Nitropropane dioxygenase
LYZ33_11350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LYZ33_11355	COG0250	Participates in transcription elongation, termination and antitermination
LYZ33_11380	COG0596	Alpha beta hydrolase
LYZ33_11395	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LYZ33_11400	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LYZ33_11415	COG0706	membrane insertase activity
LYZ33_11420	COG2195	Cleaves the N-terminal amino acid of tripeptides
LYZ33_11425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LYZ33_11430	COG0346	lactoylglutathione lyase activity
LYZ33_11440	COG1376	ErfK ybiS ycfS ynhG family protein
LYZ33_11445	COG4129	membrane
LYZ33_11450	COG1126	abc transporter atp-binding protein
LYZ33_11455	COG0765	amino acid transport
LYZ33_11460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LYZ33_11470	COG1597	lipid kinase activity
LYZ33_11475	COG0508	dehydrogenase complex catalyzes the overall conversion of
LYZ33_11480	COG0022	dehydrogenase e1 component
LYZ33_11485	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LYZ33_11490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LYZ33_11495	COG3426	butyrate kinase activity
LYZ33_11500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LYZ33_11505	COG0280	phosphate acetyltransferase
LYZ33_11510	COG3829	transcription factor binding
LYZ33_11510	COG3290	protein histidine kinase activity
LYZ33_11520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LYZ33_11525	COG2079	MmgE PrpD family protein
LYZ33_11530	COG0372	Belongs to the citrate synthase family
LYZ33_11535	COG1960	acyl-CoA dehydrogenase activity
LYZ33_11540	COG1250	3-hydroxyacyl-CoA dehydrogenase
LYZ33_11545	COG0183	Belongs to the thiolase family
LYZ33_11550	COG0584	glycerophosphoryl diester phosphodiesterase
LYZ33_11555	COG0860	N-Acetylmuramoyl-L-alanine amidase
LYZ33_11580	COG1902	pentaerythritol trinitrate reductase activity
LYZ33_11595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LYZ33_11600	COG0745	RESPONSE REGULATOR receiver
LYZ33_11605	COG0750	zinc metalloprotease
LYZ33_11610	COG0497	DNA recombination
LYZ33_11620	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LYZ33_11630	COG0142	geranyltranstransferase activity
LYZ33_11640	COG1570	exodeoxyribonuclease VII activity
LYZ33_11655	COG1302	Protein conserved in bacteria
LYZ33_11660	COG0439	Biotin carboxylase
LYZ33_11665	COG0511	ligase activity, forming carbon-carbon bonds
LYZ33_11705	COG3854	ATPases associated with a variety of cellular activities
LYZ33_11720	COG0006	proline dipeptidase activity
LYZ33_11730	COG3872	metal-dependent enzyme
LYZ33_11740	COG1752	Esterase of the alpha-beta hydrolase superfamily
LYZ33_11755	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LYZ33_11775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LYZ33_11790	COG1396	sequence-specific DNA binding
LYZ33_11800	COG0681	Belongs to the peptidase S26 family
LYZ33_11825	COG4940	Competence protein ComGF
LYZ33_11835	COG4970	Tfp pilus assembly protein FimT
LYZ33_11840	COG4537	Required for transformation and DNA binding
LYZ33_11845	COG1459	type II secretion system
LYZ33_11850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LYZ33_11855	COG0598	Magnesium transport protein CorA
LYZ33_11860	COG1253	flavin adenine dinucleotide binding
LYZ33_11865	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_11875	COG1393	Belongs to the ArsC family
LYZ33_11885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LYZ33_11895	COG0011	TIGRFAM Protein of
LYZ33_11905	COG2866	Carboxypeptidase
LYZ33_11910	COG1940	carbohydrate kinase activity
LYZ33_11915	COG4483	Protein conserved in bacteria
LYZ33_11920	COG1757	Na H antiporter
LYZ33_11930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LYZ33_11945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LYZ33_11950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LYZ33_11955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LYZ33_11960	COG0581	inorganic phosphate transmembrane transporter activity
LYZ33_11965	COG0573	inorganic phosphate transmembrane transporter activity
LYZ33_11970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LYZ33_11975	COG0768	penicillin binding
LYZ33_11980	COG0477	Major facilitator Superfamily
LYZ33_11985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LYZ33_11990	COG2839	Protein conserved in bacteria
LYZ33_11995	COG5521	maltodextrose utilization protein MalA
LYZ33_12000	COG1388	LysM domain
LYZ33_12010	COG4709	membrane
LYZ33_12015	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LYZ33_12020	COG0735	belongs to the Fur family
LYZ33_12025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LYZ33_12040	COG0513	Belongs to the DEAD box helicase family
LYZ33_12055	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LYZ33_12060	COG2384	SAM-dependent methyltransferase
LYZ33_12065	COG2010	Cytochrome c
LYZ33_12070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LYZ33_12075	COG0358	DNA primase activity
LYZ33_12090	COG0517	IMP dehydrogenase activity
LYZ33_12095	COG0751	glycine-tRNA ligase activity
LYZ33_12115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LYZ33_12120	COG0295	cytidine deaminase activity
LYZ33_12125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LYZ33_12135	COG1480	7TM receptor with intracellular HD hydrolase
LYZ33_12140	COG1702	phosphate starvation-inducible protein PhoH
LYZ33_12145	COG0561	phosphatase activity
LYZ33_12160	COG4864	UPF0365 protein
LYZ33_12165	COG1030	water channel activity
LYZ33_12170	COG1610	YqeY-like protein
LYZ33_12180	COG1283	sodium-dependent phosphate transmembrane transporter activity
LYZ33_12185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LYZ33_12190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LYZ33_12220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LYZ33_12235	COG0860	N-Acetylmuramoyl-L-alanine amidase
LYZ33_12265	COG0658	competence protein
LYZ33_12265	COG2333	competence protein COMEC
LYZ33_12270	COG2131	deaminase
LYZ33_12275	COG1555	photosystem II stabilization
LYZ33_12275	COG1596	polysaccharide export
LYZ33_12280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LYZ33_12285	COG2226	methyltransferase
LYZ33_12290	COG0799	negative regulation of ribosome biogenesis
LYZ33_12295	COG1713	HD superfamily hydrolase involved in NAD metabolism
LYZ33_12305	COG1534	Rna-binding protein
LYZ33_12310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LYZ33_12315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LYZ33_12320	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LYZ33_12330	COG2755	lipolytic protein G-D-S-L family
LYZ33_12340	COG0398	Pfam SNARE associated Golgi protein
LYZ33_12370	COG1794	racemase activity, acting on amino acids and derivatives
LYZ33_12390	COG0656	L-ascorbic acid biosynthetic process
LYZ33_12405	COG3723	Recombinational DNA repair protein, rece pathway
LYZ33_12425	COG5002	protein histidine kinase activity
LYZ33_12425	COG0642	Histidine kinase
LYZ33_12430	COG0745	RESPONSE REGULATOR receiver
LYZ33_12435	COG2311	Membrane
LYZ33_12440	COG0454	-acetyltransferase
LYZ33_12445	COG0563	adenylate kinase activity
LYZ33_12455	COG2814	Major facilitator Superfamily
LYZ33_12460	COG0456	acetyltransferase
LYZ33_12465	COG2318	DinB family
LYZ33_12475	COG0561	phosphatase activity
LYZ33_12480	COG0561	phosphatase activity
LYZ33_12490	COG1482	cell wall glycoprotein biosynthetic process
LYZ33_12495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LYZ33_12495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LYZ33_12495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LYZ33_12500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LYZ33_12500	COG3711	transcriptional antiterminator
LYZ33_12510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LYZ33_12515	COG0583	DNA-binding transcription factor activity
LYZ33_12520	COG2814	Major facilitator Superfamily
LYZ33_12525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LYZ33_12525	COG2124	cytochrome p450
LYZ33_12530	COG1309	transcriptional regulator
LYZ33_12535	COG2226	methyltransferase
LYZ33_12550	COG2116	formate transmembrane transporter activity
LYZ33_12555	COG5609	conserved protein (DUF2294)
LYZ33_12560	COG3383	formate dehydrogenase (NAD+) activity
LYZ33_12565	COG2427	Protein of unknown function (DUF1641)
LYZ33_12575	COG0626	cystathionine gamma-synthase activity
LYZ33_12580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LYZ33_12605	COG0768	penicillin binding
LYZ33_12620	COG0826	peptidase U32
LYZ33_12625	COG0826	peptidase U32
LYZ33_12630	COG4122	O-methyltransferase activity
LYZ33_12635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LYZ33_12660	COG0628	permease
LYZ33_12665	COG1126	abc transporter atp-binding protein
LYZ33_12670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LYZ33_12675	COG0765	amino acid transport
LYZ33_12680	COG0765	amino acid transport
LYZ33_12695	COG3881	PFAM PRC-barrel domain
LYZ33_12700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LYZ33_12705	COG0457	Tetratricopeptide repeat
LYZ33_12715	COG1104	cysteine desulfurase activity
LYZ33_12720	COG1959	2 iron, 2 sulfur cluster binding
LYZ33_12725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LYZ33_12730	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LYZ33_12755	COG0860	N-Acetylmuramoyl-L-alanine amidase
LYZ33_12755	COG3103	Sh3 type 3 domain protein
LYZ33_12755	COG4991	sh3 domain protein
LYZ33_12765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LYZ33_12775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LYZ33_12775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LYZ33_12780	COG5416	Lipopolysaccharide assembly protein A domain
LYZ33_12785	COG0490	domain, Protein
LYZ33_12790	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LYZ33_12790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LYZ33_12800	COG2244	polysaccharide biosynthetic process
LYZ33_12805	COG2323	membrane
LYZ33_12815	COG1862	Preprotein translocase
LYZ33_12855	COG1388	LysM domain
LYZ33_12865	COG0157	Belongs to the NadC ModD family
LYZ33_12870	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LYZ33_12875	COG1104	cysteine desulfurase activity
LYZ33_12880	COG1827	regulation of RNA biosynthetic process
LYZ33_12885	COG0077	Prephenate dehydratase
LYZ33_12900	COG3290	protein histidine kinase activity
LYZ33_12905	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LYZ33_12910	COG2868	ribosomal protein
LYZ33_12920	COG1994	Peptidase M50
LYZ33_12925	COG0739	heme binding
LYZ33_12930	COG2894	cell division
LYZ33_12940	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LYZ33_12950	COG1077	Cell shape determining protein MreB Mrl
LYZ33_12970	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LYZ33_12975	COG0285	dihydrofolate synthase activity
LYZ33_12980	COG0525	valine-tRNA ligase activity
LYZ33_12990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LYZ33_12995	COG1388	LysM domain
LYZ33_13005	COG0113	porphobilinogen synthase activity
LYZ33_13010	COG1587	Uroporphyrinogen-III synthase
LYZ33_13020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LYZ33_13040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LYZ33_13045	COG1067	ATP-dependent peptidase activity
LYZ33_13045	COG0470	DNA polymerase III
LYZ33_13060	COG0457	Tetratricopeptide repeat
LYZ33_13060	COG1477	protein flavinylation
LYZ33_13075	COG0473	3-isopropylmalate dehydrogenase activity
LYZ33_13090	COG0440	acetolactate synthase activity
LYZ33_13095	COG0028	Belongs to the TPP enzyme family
LYZ33_13120	COG0622	Phosphoesterase
LYZ33_13125	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LYZ33_13135	COG5401	PFAM Sporulation and spore germination
LYZ33_13145	COG1846	Transcriptional regulator
LYZ33_13150	COG2197	response regulator
LYZ33_13155	COG0824	Thioesterase
LYZ33_13160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LYZ33_13165	COG1053	succinate dehydrogenase
LYZ33_13170	COG2009	succinate dehydrogenase
LYZ33_13175	COG1719	4-vinyl reductase, 4VR
LYZ33_13180	COG0527	aspartate kinase activity
LYZ33_13190	COG3118	belongs to the thioredoxin family
LYZ33_13195	COG3534	alpha-L-arabinofuranosidase
LYZ33_13200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LYZ33_13205	COG2086	electron transfer activity
LYZ33_13210	COG1024	Enoyl-CoA hydratase
LYZ33_13215	COG1309	transcriptional regulator
LYZ33_13220	COG0318	PFAM AMP-dependent synthetase and ligase
LYZ33_13230	COG3766	membrane
LYZ33_13240	COG1796	DNA polymerase
LYZ33_13240	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LYZ33_13245	COG1286	toxin biosynthetic process
LYZ33_13260	COG0072	phenylalanine-tRNA ligase activity
LYZ33_13260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LYZ33_13265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LYZ33_13270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LYZ33_13280	COG3835	regulator
LYZ33_13285	COG0277	FAD linked oxidase domain protein
LYZ33_13290	COG0247	lactate metabolic process
LYZ33_13295	COG1966	Carbon starvation protein
LYZ33_13300	COG3534	alpha-L-arabinofuranosidase
LYZ33_13305	COG0395	ABC-type sugar transport system, permease component
LYZ33_13310	COG1175	transmembrane transport
LYZ33_13315	COG1653	transport
LYZ33_13325	COG0647	UMP catabolic process
LYZ33_13330	COG0235	Class ii aldolase
LYZ33_13335	COG1069	ribulokinase activity
LYZ33_13340	COG2160	L-arabinose isomerase activity
LYZ33_13345	COG3507	Belongs to the glycosyl hydrolase 43 family
LYZ33_13350	COG1363	Peptidase, m42
LYZ33_13360	COG3326	Membrane
LYZ33_13365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LYZ33_13375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LYZ33_13380	COG1346	cytolysis
LYZ33_13385	COG1380	Effector of murein hydrolase LrgA
LYZ33_13390	COG3279	Response regulator of the LytR AlgR family
LYZ33_13395	COG3275	phosphorelay sensor kinase activity
LYZ33_13400	COG1011	Hydrolase
LYZ33_13415	COG0398	Pfam SNARE associated Golgi protein
LYZ33_13420	COG1484	DNA-dependent DNA replication
LYZ33_13425	COG3611	Membrane attachment protein
LYZ33_13440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LYZ33_13445	COG1733	regulation of RNA biosynthetic process
LYZ33_13450	COG2814	Major facilitator Superfamily
LYZ33_13455	COG0656	L-ascorbic acid biosynthetic process
LYZ33_13460	COG0237	dephospho-CoA kinase activity
LYZ33_13465	COG1971	Probably functions as a manganese efflux pump
LYZ33_13470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LYZ33_13475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LYZ33_13475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LYZ33_13480	COG5002	protein histidine kinase activity
LYZ33_13485	COG0745	RESPONSE REGULATOR receiver
LYZ33_13495	COG0538	isocitrate dehydrogenase activity
LYZ33_13500	COG0372	Belongs to the citrate synthase family
LYZ33_13510	COG0457	Tetratricopeptide repeat
LYZ33_13545	COG0628	permease
LYZ33_13550	COG3030	protein affecting phage T7 exclusion by the F plasmid
LYZ33_13555	COG0469	pyruvate kinase activity
LYZ33_13575	COG0281	malic enzyme
LYZ33_13580	COG0587	DNA-directed DNA polymerase activity
LYZ33_13600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LYZ33_13610	COG4109	DRTGG domain
LYZ33_13620	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_13635	COG0521	Mo-molybdopterin cofactor biosynthetic process
LYZ33_13645	COG0827	DNA restriction-modification system
LYZ33_13650	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LYZ33_13655	COG3874	Sporulation protein YtfJ
LYZ33_13665	COG1714	RDD family
LYZ33_13670	COG0616	signal peptide processing
LYZ33_13675	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LYZ33_13680	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LYZ33_13685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LYZ33_13700	COG1104	cysteine desulfurase activity
LYZ33_13705	COG1114	Component of the transport system for branched-chain amino acids
LYZ33_13715	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LYZ33_13720	COG1309	transcriptional regulator
LYZ33_13725	COG1956	GAF domain-containing protein
LYZ33_13730	COG2199	diguanylate cyclase activity
LYZ33_13730	COG2203	Gaf domain
LYZ33_13740	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_13745	COG4282	regulation of fungal-type cell wall biogenesis
LYZ33_13750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LYZ33_13750	COG1017	nitric oxide dioxygenase activity
LYZ33_13760	COG0693	protein deglycase activity
LYZ33_13775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LYZ33_13780	COG1378	Sugar-specific transcriptional regulator TrmB
LYZ33_13800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LYZ33_13805	COG0454	-acetyltransferase
LYZ33_13810	COG0517	IMP dehydrogenase activity
LYZ33_13815	COG0123	including yeast histone deacetylase and acetoin utilization protein
LYZ33_13820	COG1360	Flagellar Motor Protein
LYZ33_13825	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LYZ33_13830	COG1609	Transcriptional regulator
LYZ33_13835	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LYZ33_13835	COG1605	Chorismate mutase
LYZ33_13840	COG3118	belongs to the thioredoxin family
LYZ33_13845	COG4980	gas vesicle protein
LYZ33_13850	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LYZ33_13860	COG1674	ftsk spoiiie
LYZ33_13865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LYZ33_13875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_13885	COG1363	Peptidase, m42
LYZ33_13890	COG5584	Small secreted protein
LYZ33_13895	COG0281	malic enzyme
LYZ33_13900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LYZ33_13915	COG0510	thiamine kinase activity
LYZ33_13920	COG1597	lipid kinase activity
LYZ33_13930	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LYZ33_13935	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LYZ33_13940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LYZ33_13945	COG2252	PERMEase
LYZ33_13950	COG4473	ABC transporter
LYZ33_13955	COG1131	(ABC) transporter
LYZ33_13960	COG1349	DNA-binding transcription factor activity
LYZ33_13965	COG1187	pseudouridine synthase activity
LYZ33_13970	COG2244	polysaccharide biosynthetic process
LYZ33_13975	COG2081	HI0933 family
LYZ33_13980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LYZ33_13990	COG1609	Transcriptional regulator
LYZ33_13995	COG1653	transport
LYZ33_14000	COG1175	transmembrane transport
LYZ33_14005	COG0395	ABC-type sugar transport system, permease component
LYZ33_14010	COG1486	melibiose metabolic process
LYZ33_14020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LYZ33_14035	COG2202	Pas domain
LYZ33_14035	COG1366	Belongs to the anti-sigma-factor antagonist family
LYZ33_14040	COG2814	Major facilitator Superfamily
LYZ33_14045	COG5522	Integral membrane protein (intg_mem_TP0381)
LYZ33_14050	COG0577	efflux transmembrane transporter activity
LYZ33_14055	COG1136	(ABC) transporter
LYZ33_14060	COG2205	protein histidine kinase activity
LYZ33_14065	COG0745	RESPONSE REGULATOR receiver
LYZ33_14070	COG0577	efflux transmembrane transporter activity
LYZ33_14075	COG1136	(ABC) transporter
LYZ33_14095	COG1131	(ABC) transporter
LYZ33_14100	COG1725	Transcriptional regulator
LYZ33_14115	COG1242	4 iron, 4 sulfur cluster binding
LYZ33_14120	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LYZ33_14130	COG0584	glycerophosphoryl diester phosphodiesterase
LYZ33_14140	COG2267	carboxylic ester hydrolase activity
LYZ33_14145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LYZ33_14150	COG1113	amino acid transport
LYZ33_14155	COG0367	asparagine synthase
LYZ33_14175	COG1506	peptidase
LYZ33_14180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LYZ33_14185	COG1116	anion transmembrane transporter activity
LYZ33_14190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LYZ33_14195	COG0494	nUDIX hydrolase
LYZ33_14200	COG4824	toxin secretion phage lysis holin
LYZ33_14205	COG0783	Belongs to the Dps family
LYZ33_14230	COG0288	reversible hydration of carbon dioxide
LYZ33_14240	COG1271	oxidase subunit
LYZ33_14245	COG1294	oxidase, subunit
LYZ33_14255	COG4948	Mandelate Racemase Muconate Lactonizing
LYZ33_14265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LYZ33_14270	COG0596	Alpha beta hydrolase
LYZ33_14280	COG1169	isochorismate synthase
LYZ33_14285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LYZ33_14290	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LYZ33_14415	COG3859	Proton-coupled thiamine transporter YuaJ
LYZ33_14420	COG2268	Band 7 protein
LYZ33_14425	COG1585	Membrane protein implicated in regulation of membrane protease activity
LYZ33_14430	COG2318	DinB family
LYZ33_14440	COG1454	alcohol dehydrogenase
LYZ33_14445	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_14450	COG1510	regulation of RNA biosynthetic process
LYZ33_14460	COG0569	domain protein
LYZ33_14465	COG1705	Flagellar rod assembly protein muramidase FlgJ
LYZ33_14470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LYZ33_14470	COG1017	nitric oxide dioxygenase activity
LYZ33_14485	COG0457	Tetratricopeptide repeat
LYZ33_14510	COG0628	permease
LYZ33_14515	COG0673	inositol 2-dehydrogenase activity
LYZ33_14520	COG0693	protein deglycase activity
LYZ33_14525	COG0840	transmembrane signaling receptor activity
LYZ33_14530	COG0840	transmembrane signaling receptor activity
LYZ33_14535	COG0840	transmembrane signaling receptor activity
LYZ33_14540	COG0840	transmembrane signaling receptor activity
LYZ33_14555	COG2070	2-Nitropropane dioxygenase
LYZ33_14560	COG0432	Pfam Uncharacterised protein family UPF0047
LYZ33_14565	COG0366	Alpha amylase catalytic
LYZ33_14570	COG1253	flavin adenine dinucleotide binding
LYZ33_14575	COG2738	Putative neutral zinc metallopeptidase
LYZ33_14590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LYZ33_14615	COG1335	isochorismatase
LYZ33_14620	COG1979	alcohol dehydrogenase
LYZ33_14625	COG1979	alcohol dehydrogenase
LYZ33_14630	COG2155	Conserved Protein
LYZ33_14635	COG1098	S1 RNA binding domain
LYZ33_14640	COG0436	Aminotransferase
LYZ33_14645	COG1522	sequence-specific DNA binding
LYZ33_14650	COG2267	carboxylic ester hydrolase activity
LYZ33_14660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LYZ33_14665	COG2205	protein histidine kinase activity
LYZ33_14675	COG5018	Exonuclease
LYZ33_14680	COG2814	Major facilitator Superfamily
LYZ33_14685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LYZ33_14690	COG3011	Protein conserved in bacteria
LYZ33_14700	COG3290	protein histidine kinase activity
LYZ33_14705	COG4565	transcriptional regulatory protein
LYZ33_14710	COG1744	ABC transporter substrate-binding protein PnrA-like
LYZ33_14715	COG3845	ABC transporter
LYZ33_14720	COG4603	Belongs to the binding-protein-dependent transport system permease family
LYZ33_14725	COG1079	Belongs to the binding-protein-dependent transport system permease family
LYZ33_14735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LYZ33_14735	COG2111	Na H antiporter
LYZ33_14740	COG2111	Na H antiporter
LYZ33_14745	COG1006	Multisubunit Na H antiporter MnhC subunit
LYZ33_14750	COG0651	ATP synthesis coupled electron transport
LYZ33_14755	COG1863	multisubunit Na H antiporter MnhE subunit
LYZ33_14760	COG2212	antiporter activity
LYZ33_14765	COG1320	monovalent cation:proton antiporter activity
LYZ33_14770	COG2050	protein possibly involved in aromatic compounds catabolism
LYZ33_14775	COG2197	response regulator
LYZ33_14780	COG4585	Histidine kinase
LYZ33_14790	COG0142	geranyltranstransferase activity
LYZ33_14805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LYZ33_14810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LYZ33_14815	COG1335	isochorismatase
LYZ33_14820	COG5506	Protein of unknown function (DUF1694)
LYZ33_14835	COG0628	permease
LYZ33_14845	COG1418	mRNA catabolic process
LYZ33_14850	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_14860	COG1511	domain protein
LYZ33_14865	COG0433	COG0433 Predicted ATPase
LYZ33_14865	COG1674	ftsk spoiiie
LYZ33_14870	COG4499	WXG100 protein secretion system (Wss), protein YukC
LYZ33_14875	COG5417	Belongs to the EsaB family
LYZ33_14880	COG4842	Belongs to the WXG100 family
LYZ33_14885	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LYZ33_14885	COG2508	Transcriptional regulator
LYZ33_14890	COG0686	Belongs to the AlaDH PNT family
LYZ33_14895	COG5634	Uncharacterized conserved protein (DUF2278)
LYZ33_14900	COG3251	PFAM MbtH domain protein
LYZ33_14905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_14910	COG3433	isochorismatase activity
LYZ33_14910	COG1535	isochorismatase
LYZ33_14915	COG1021	2,3-dihydroxybenzoate-AMP ligase
LYZ33_14920	COG1169	isochorismate synthase
LYZ33_14925	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_14930	COG2819	hydrolase of the alpha beta superfamily
LYZ33_14935	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LYZ33_14940	COG1268	BioY protein
LYZ33_14945	COG2056	Na+-H+ antiporter family
LYZ33_14955	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LYZ33_14960	COG3584	3D domain protein
LYZ33_14975	COG1252	NADH dehydrogenase
LYZ33_15005	COG1131	(ABC) transporter
LYZ33_15030	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LYZ33_15035	COG0316	Belongs to the HesB IscA family
LYZ33_15045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LYZ33_15055	COG1252	NADH dehydrogenase
LYZ33_15060	COG4837	Protein of unknown function (DUF1462)
LYZ33_15065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LYZ33_15070	COG1506	peptidase
LYZ33_15070	COG0823	Involved in the tonB-independent uptake of proteins
LYZ33_15070	COG4946	Tricorn protease homolog
LYZ33_15080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LYZ33_15085	COG0460	homoserine dehydrogenase
LYZ33_15090	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LYZ33_15095	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LYZ33_15100	COG0647	UMP catabolic process
LYZ33_15105	COG2445	Protein of unknown function DUF86
LYZ33_15110	COG4470	Protein conserved in bacteria
LYZ33_15120	COG0739	heme binding
LYZ33_15130	COG0737	Belongs to the 5'-nucleotidase family
LYZ33_15135	COG0730	response to heat
LYZ33_15140	COG1801	Protein of unknown function DUF72
LYZ33_15155	COG2508	Transcriptional regulator
LYZ33_15175	COG2814	Major facilitator Superfamily
LYZ33_15180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LYZ33_15185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LYZ33_15190	COG2356	endonuclease I
LYZ33_15195	COG3842	ATPase activity
LYZ33_15200	COG2188	Transcriptional regulator
LYZ33_15205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LYZ33_15210	COG0395	ABC-type sugar transport system, permease component
LYZ33_15215	COG1175	transmembrane transport
LYZ33_15220	COG1653	transport
LYZ33_15225	COG2222	sugar isomerase
LYZ33_15230	COG0789	Transcriptional regulator
LYZ33_15255	COG0322	excinuclease ABC activity
LYZ33_15260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LYZ33_15265	COG2226	methyltransferase
LYZ33_15275	COG3409	Peptidoglycan-binding domain 1 protein
LYZ33_15280	COG0719	Fe-S assembly protein
LYZ33_15285	COG0822	iron-sulfur transferase activity
LYZ33_15290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LYZ33_15295	COG0719	Fe-S assembly protein
LYZ33_15300	COG0396	ATPase activity
LYZ33_15310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LYZ33_15315	COG1464	Belongs to the NlpA lipoprotein family
LYZ33_15320	COG2011	ABC-type metal ion transport system permease component
LYZ33_15325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LYZ33_15335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LYZ33_15340	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LYZ33_15355	COG1393	Belongs to the ArsC family
LYZ33_15360	COG1960	acyl-CoA dehydrogenase activity
LYZ33_15365	COG0183	Belongs to the thiolase family
LYZ33_15370	COG1024	Enoyl-CoA hydratase
LYZ33_15370	COG1250	3-hydroxyacyl-CoA dehydrogenase
LYZ33_15390	COG5577	PFAM Coat F domain
LYZ33_15395	COG1846	Transcriptional regulator
LYZ33_15400	COG0477	Major facilitator Superfamily
LYZ33_15405	COG0583	DNA-binding transcription factor activity
LYZ33_15425	COG1120	ATPase activity
LYZ33_15440	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_15445	COG0783	Belongs to the Dps family
LYZ33_15450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LYZ33_15455	COG0745	RESPONSE REGULATOR receiver
LYZ33_15460	COG2205	protein histidine kinase activity
LYZ33_15460	COG2770	Histidine kinase
LYZ33_15470	COG1309	transcriptional regulator
LYZ33_15475	COG0114	fumarate hydratase activity
LYZ33_15485	COG0697	spore germination
LYZ33_15490	COG0814	amino acid
LYZ33_15500	COG2197	response regulator
LYZ33_15505	COG4585	Histidine kinase
LYZ33_15510	COG4758	membrane
LYZ33_15515	COG3595	metallopeptidase activity
LYZ33_15520	COG1842	Phage shock protein A
LYZ33_15525	COG4758	membrane
LYZ33_15530	COG2814	Major facilitator Superfamily
LYZ33_15535	COG2096	Adenosyltransferase
LYZ33_15540	COG1120	ATPase activity
LYZ33_15545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_15550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LYZ33_15555	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_15560	COG3386	PFAM SMP-30 Gluconolaconase
LYZ33_15565	COG2205	protein histidine kinase activity
LYZ33_15570	COG0745	RESPONSE REGULATOR receiver
LYZ33_15580	COG1191	sigma factor activity
LYZ33_15590	COG2140	Oxalate decarboxylase
LYZ33_15600	COG1120	ATPase activity
LYZ33_15605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_15610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_15615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LYZ33_15620	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LYZ33_15625	COG0531	amino acid
LYZ33_15635	COG1988	membrane-bound metal-dependent
LYZ33_15640	COG1368	sulfuric ester hydrolase activity
LYZ33_15645	COG1910	domain protein
LYZ33_15650	COG0725	ABC transporter, periplasmic molybdate-binding protein
LYZ33_15655	COG4149	molybdate abc transporter
LYZ33_15660	COG2197	response regulator
LYZ33_15665	COG3850	Histidine kinase
LYZ33_15670	COG1131	(ABC) transporter
LYZ33_15680	COG0842	Transport permease protein
LYZ33_15685	COG0656	L-ascorbic acid biosynthetic process
LYZ33_15705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LYZ33_15710	COG3973	AAA domain
LYZ33_15715	COG2860	membrane
LYZ33_15725	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LYZ33_15730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LYZ33_15735	COG2217	Heavy metal translocating P-type atpase
LYZ33_15740	COG2217	Heavy metal translocating P-type atpase
LYZ33_15745	COG2608	mercury ion transmembrane transporter activity
LYZ33_15750	COG1937	Protein conserved in bacteria
LYZ33_15755	COG0673	inositol 2-dehydrogenase activity
LYZ33_15765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LYZ33_15770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LYZ33_15775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LYZ33_15780	COG1126	abc transporter atp-binding protein
LYZ33_15785	COG0765	amino acid transport
LYZ33_15790	COG0765	amino acid transport
LYZ33_15795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LYZ33_15800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LYZ33_15805	COG0454	-acetyltransferase
LYZ33_15810	COG0583	DNA-binding transcription factor activity
LYZ33_15815	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_15820	COG2732	(Barnase) inhibitor
LYZ33_15835	COG2732	(Barnase) inhibitor
LYZ33_15850	COG0557	exoribonuclease II activity
LYZ33_15855	COG1647	Serine aminopeptidase, S33
LYZ33_15860	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LYZ33_15865	COG1476	TRANSCRIPTIONal
LYZ33_15870	COG1396	sequence-specific DNA binding
LYZ33_15875	COG1396	sequence-specific DNA binding
LYZ33_15880	COG1733	regulation of RNA biosynthetic process
LYZ33_15905	COG1131	(ABC) transporter
LYZ33_15910	COG1174	glycine betaine transport
LYZ33_15915	COG1732	Glycine betaine
LYZ33_15920	COG1174	glycine betaine transport
LYZ33_15925	COG1125	glycine betaine transport
LYZ33_15925	COG0517	IMP dehydrogenase activity
LYZ33_15930	COG1510	regulation of RNA biosynthetic process
LYZ33_15935	COG1174	glycine betaine transport
LYZ33_15940	COG1732	Glycine betaine
LYZ33_15945	COG1174	glycine betaine transport
LYZ33_15950	COG1125	glycine betaine transport
LYZ33_15950	COG0517	IMP dehydrogenase activity
LYZ33_15955	COG1510	regulation of RNA biosynthetic process
LYZ33_15960	COG2095	MarC family integral membrane protein
LYZ33_15965	COG3064	Membrane
LYZ33_15970	COG4640	response to antibiotic
LYZ33_15975	COG0456	acetyltransferase
LYZ33_15990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LYZ33_16005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LYZ33_16010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LYZ33_16015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LYZ33_16025	COG2234	aminopeptidase activity
LYZ33_16045	COG0126	phosphoglycerate kinase activity
LYZ33_16050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LYZ33_16055	COG2390	Transcriptional regulator
LYZ33_16060	COG2814	Major facilitator Superfamily
LYZ33_16065	COG1609	Transcriptional regulator
LYZ33_16075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LYZ33_16090	COG0697	spore germination
LYZ33_16095	COG1113	amino acid transport
LYZ33_16105	COG1609	Transcriptional regulator
LYZ33_16115	COG0561	phosphatase activity
LYZ33_16120	COG1737	Transcriptional regulator
LYZ33_16125	COG1070	Carbohydrate kinase
LYZ33_16150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LYZ33_16155	COG2186	Transcriptional regulator
LYZ33_16160	COG1620	l-lactate permease
LYZ33_16165	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LYZ33_16175	COG5039	Polysaccharide pyruvyl transferase
LYZ33_16180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LYZ33_16185	COG0110	maltose O-acetyltransferase activity
LYZ33_16190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LYZ33_16195	COG2244	polysaccharide biosynthetic process
LYZ33_16200	COG1216	Glycosyl transferase, family 2
LYZ33_16205	COG5039	Polysaccharide pyruvyl transferase
LYZ33_16210	COG1216	Glycosyl transferase, family 2
LYZ33_16220	COG0438	transferase activity, transferring glycosyl groups
LYZ33_16225	COG1215	transferase activity, transferring glycosyl groups
LYZ33_16230	COG0438	transferase activity, transferring glycosyl groups
LYZ33_16235	COG1086	Polysaccharide biosynthesis protein
LYZ33_16240	COG0489	protein tyrosine kinase activity
LYZ33_16245	COG3944	biosynthesis protein
LYZ33_16250	COG1396	sequence-specific DNA binding
LYZ33_16255	COG2272	Belongs to the type-B carboxylesterase lipase family
LYZ33_16265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LYZ33_16270	COG2364	Membrane
LYZ33_16275	COG0456	acetyltransferase
LYZ33_16280	COG3479	Phenolic acid decarboxylase
LYZ33_16330	COG2223	nitrite transmembrane transporter activity
LYZ33_16335	COG1609	Transcriptional regulator
LYZ33_16345	COG0583	DNA-binding transcription factor activity
LYZ33_16350	COG2828	Protein conserved in bacteria
LYZ33_16355	COG0477	Major facilitator Superfamily
LYZ33_16355	COG2814	Major facilitator Superfamily
LYZ33_16360	COG1611	Belongs to the LOG family
LYZ33_16365	COG1694	Mazg nucleotide pyrophosphohydrolase
LYZ33_16370	COG0659	secondary active sulfate transmembrane transporter activity
LYZ33_16375	COG0288	reversible hydration of carbon dioxide
LYZ33_16380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LYZ33_16385	COG4290	ribonuclease
LYZ33_16390	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LYZ33_16395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LYZ33_16405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LYZ33_16415	COG1051	belongs to the nudix hydrolase family
LYZ33_16420	COG0492	ferredoxin-NADP+ reductase activity
LYZ33_16425	COG3883	PFAM NLP P60 protein
LYZ33_16425	COG0791	NLP P60 protein
LYZ33_16430	COG0457	Tetratricopeptide repeat
LYZ33_16435	COG5002	protein histidine kinase activity
LYZ33_16440	COG0745	RESPONSE REGULATOR receiver
LYZ33_16450	COG1132	(ABC) transporter
LYZ33_16455	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LYZ33_16455	COG0140	phosphoribosyl-ATP diphosphatase activity
LYZ33_16480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LYZ33_16495	COG4990	cell redox homeostasis
LYZ33_16500	COG0110	maltose O-acetyltransferase activity
LYZ33_16520	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LYZ33_16530	COG2188	Transcriptional regulator
LYZ33_16535	COG1309	transcriptional regulator
LYZ33_16540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LYZ33_16545	COG1950	PFAM Membrane protein of
LYZ33_16550	COG1983	PspC domain protein
LYZ33_16555	COG3595	metallopeptidase activity
LYZ33_16570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LYZ33_16580	COG4897	Protein conserved in bacteria
LYZ33_16585	COG3848	Pyruvate phosphate dikinase
LYZ33_16585	COG0574	Belongs to the PEP-utilizing enzyme family
LYZ33_16590	COG1309	transcriptional regulator
LYZ33_16595	COG2814	Major facilitator Superfamily
LYZ33_16615	COG1132	(ABC) transporter
LYZ33_16620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LYZ33_16640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LYZ33_16650	COG0793	Belongs to the peptidase S41A family
LYZ33_16650	COG3409	Peptidoglycan-binding domain 1 protein
LYZ33_16655	COG3420	alginic acid biosynthetic process
LYZ33_16660	COG2177	Part of the ABC transporter FtsEX involved in
LYZ33_16665	COG2884	Cell division ATP-binding protein ftsE
LYZ33_16670	COG2010	Cytochrome c
LYZ33_16675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LYZ33_16690	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LYZ33_16705	COG1516	flagellar protein fliS
LYZ33_16710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LYZ33_16715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LYZ33_16735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LYZ33_16740	COG4786	Flagellar basal body rod
LYZ33_16740	COG1256	bacterial-type flagellum assembly
LYZ33_16745	COG3418	PFAM FlgN family protein
LYZ33_16750	COG2747	anti-sigma28 factor FlgM
LYZ33_16760	COG1040	competence protein
LYZ33_16770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LYZ33_16775	COG1307	EDD domain protein, DegV family
LYZ33_16780	COG2197	response regulator
LYZ33_16785	COG4585	Histidine kinase
LYZ33_16790	COG1739	Uncharacterized protein family UPF0029
LYZ33_16795	COG1316	TRANSCRIPTIONal
LYZ33_16800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LYZ33_16805	COG0438	transferase activity, transferring glycosyl groups
LYZ33_16810	COG1215	transferase activity, transferring glycosyl groups
LYZ33_16815	COG3206	protein involved in exopolysaccharide biosynthesis
LYZ33_16820	COG3307	-O-antigen
LYZ33_16825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LYZ33_16830	COG0438	transferase activity, transferring glycosyl groups
LYZ33_16830	COG0297	glycogen (starch) synthase activity
LYZ33_16835	COG2244	polysaccharide biosynthetic process
LYZ33_16845	COG2247	cell wall binding repeat
LYZ33_16845	COG0860	N-Acetylmuramoyl-L-alanine amidase
LYZ33_16850	COG2247	cell wall binding repeat
LYZ33_16850	COG2385	sporulation resulting in formation of a cellular spore
LYZ33_16860	COG1316	TRANSCRIPTIONal
LYZ33_16865	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LYZ33_16870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LYZ33_16875	COG1134	teichoic acid transport
LYZ33_16880	COG1682	transport, permease protein
LYZ33_16885	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LYZ33_16895	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LYZ33_16900	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LYZ33_16905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LYZ33_16910	COG4193	domain, Protein
LYZ33_16915	COG1482	cell wall glycoprotein biosynthetic process
LYZ33_16920	COG0697	spore germination
LYZ33_16925	COG0814	amino acid
LYZ33_16935	COG1215	transferase activity, transferring glycosyl groups
LYZ33_16940	COG2814	Major facilitator Superfamily
LYZ33_16945	COG1316	TRANSCRIPTIONal
LYZ33_16950	COG0561	phosphatase activity
LYZ33_16955	COG2433	Pfam Transposase IS66
LYZ33_16960	COG0791	NLP P60 protein
LYZ33_16970	COG2843	Capsule synthesis protein
LYZ33_16980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LYZ33_16985	COG0697	spore germination
LYZ33_16990	COG0814	amino acid
LYZ33_17000	COG1609	Transcriptional regulator
LYZ33_17005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LYZ33_17015	COG1129	ABC transporter
LYZ33_17020	COG1172	Belongs to the binding-protein-dependent transport system permease family
LYZ33_17025	COG1879	ABC-type sugar transport system periplasmic component
LYZ33_17030	COG3103	Sh3 type 3 domain protein
LYZ33_17035	COG2249	NAD(P)H dehydrogenase (quinone) activity
LYZ33_17040	COG3527	Alpha-acetolactate decarboxylase
LYZ33_17045	COG0028	Belongs to the TPP enzyme family
LYZ33_17050	COG0583	DNA-binding transcription factor activity
LYZ33_17055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LYZ33_17070	COG5337	Spore coat protein CotH
LYZ33_17080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LYZ33_17090	COG0405	Gamma-glutamyltransferase
LYZ33_17095	COG1522	sequence-specific DNA binding
LYZ33_17100	COG2059	Chromate
LYZ33_17105	COG2059	Chromate
LYZ33_17115	COG0655	NAD(P)H dehydrogenase (quinone) activity
LYZ33_17120	COG0583	DNA-binding transcription factor activity
LYZ33_17145	COG5444	nuclease activity
LYZ33_17160	COG3878	Protein conserved in bacteria
LYZ33_17165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LYZ33_17170	COG4464	protein tyrosine phosphatase activity
LYZ33_17175	COG0489	protein tyrosine kinase activity
LYZ33_17180	COG3944	biosynthesis protein
LYZ33_17190	COG4715	Zinc finger, swim domain protein
LYZ33_17195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LYZ33_17200	COG0561	phosphatase activity
LYZ33_17205	COG1349	DNA-binding transcription factor activity
LYZ33_17210	COG0629	single-stranded DNA binding
LYZ33_17235	COG0457	Tetratricopeptide repeat
LYZ33_17240	COG4786	Flagellar basal body rod
LYZ33_17245	COG4786	Flagellar basal body rod
LYZ33_17250	COG1077	Cell shape determining protein MreB Mrl
LYZ33_17255	COG1609	Transcriptional regulator
LYZ33_17260	COG1846	Transcriptional regulator
LYZ33_17265	COG2814	Major facilitator Superfamily
LYZ33_17270	COG1953	Uracil, thiamine, allantoin
LYZ33_17275	COG0477	Major facilitator Superfamily
LYZ33_17280	COG1335	isochorismatase
LYZ33_17285	COG0004	ammonium transporteR
LYZ33_17290	COG0347	Belongs to the P(II) protein family
LYZ33_17295	COG0772	Belongs to the SEDS family
LYZ33_17300	COG0671	phosphoesterase, PA-phosphatase related
LYZ33_17310	COG0739	heme binding
LYZ33_17315	COG1247	-acetyltransferase
LYZ33_17330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LYZ33_17340	COG0726	polysaccharide deacetylase
LYZ33_17345	COG1959	2 iron, 2 sulfur cluster binding
LYZ33_17360	COG0831	urea catabolic process
LYZ33_17365	COG3237	CsbD-like
LYZ33_17370	COG1994	Peptidase M50
LYZ33_17375	COG0457	Tetratricopeptide repeat
LYZ33_17385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LYZ33_17395	COG2304	oxidoreductase activity
LYZ33_17400	COG2304	oxidoreductase activity
LYZ33_17405	COG2385	sporulation resulting in formation of a cellular spore
LYZ33_17410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LYZ33_17420	COG4836	Membrane
LYZ33_17490	COG0698	ribose 5-phosphate isomerase
LYZ33_17495	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LYZ33_17505	COG0009	L-threonylcarbamoyladenylate synthase
LYZ33_17510	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LYZ33_17530	COG2890	protein-(glutamine-N5) methyltransferase activity
LYZ33_17535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LYZ33_17540	COG0346	lactoylglutathione lyase activity
LYZ33_17545	COG0789	Transcriptional regulator
LYZ33_17550	COG0679	Auxin Efflux Carrier
LYZ33_17555	COG0281	malic enzyme
LYZ33_17570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LYZ33_17580	COG1494	fructose-1,6-bisphosphatase
LYZ33_17585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LYZ33_17595	COG0191	fructose-bisphosphate aldolase activity
LYZ33_17600	COG2204	response regulator
LYZ33_17605	COG4821	SIS domain
LYZ33_17620	COG2181	nitrate reductase activity
LYZ33_17620	COG0247	lactate metabolic process
LYZ33_17625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LYZ33_17640	COG1132	(ABC) transporter
LYZ33_17645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LYZ33_17655	COG2181	nitrate reductase activity
LYZ33_17660	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LYZ33_17665	COG1140	nitrate reductase beta subunit
LYZ33_17670	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LYZ33_17675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LYZ33_17685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LYZ33_17690	COG2223	nitrite transmembrane transporter activity
LYZ33_17700	COG4506	Protein conserved in bacteria
LYZ33_17710	COG3391	amine dehydrogenase activity
LYZ33_17715	COG3391	amine dehydrogenase activity
LYZ33_17720	COG0457	Tetratricopeptide repeat
LYZ33_17760	COG0010	Belongs to the arginase family
LYZ33_17765	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LYZ33_17770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LYZ33_17785	COG1994	Peptidase M50
LYZ33_17790	COG1942	4-Oxalocrotonate Tautomerase
LYZ33_17795	COG1846	Transcriptional regulator
LYZ33_17800	COG0531	amino acid
LYZ33_17805	COG3465	dGTPase activity
LYZ33_17810	COG1078	dGTPase activity
LYZ33_17825	COG1695	Transcriptional regulator
LYZ33_17835	COG1131	(ABC) transporter
LYZ33_17840	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LYZ33_17870	COG0583	DNA-binding transcription factor activity
LYZ33_17875	COG2855	membrane
LYZ33_17880	COG0280	phosphate acetyltransferase
LYZ33_17890	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_17895	COG0436	Aminotransferase
LYZ33_17925	COG2814	Major facilitator Superfamily
LYZ33_17930	COG2814	Major facilitator Superfamily
LYZ33_17935	COG0833	amino acid
LYZ33_17940	COG4187	Peptidase family M20/M25/M40
LYZ33_17945	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_17950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LYZ33_17960	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LYZ33_17965	COG1091	dTDP-4-dehydrorhamnose reductase activity
LYZ33_17970	COG1088	dTDP-glucose 4,6-dehydratase activity
LYZ33_17975	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LYZ33_17980	COG3980	spore coat polysaccharide biosynthesis protein
LYZ33_17985	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LYZ33_17990	COG2089	acid synthase
LYZ33_17995	COG0456	acetyltransferase
LYZ33_18000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LYZ33_18005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LYZ33_18010	COG0463	Glycosyl transferase, family 2
LYZ33_18020	COG2363	Small membrane protein
LYZ33_18025	COG2233	PERMEase
LYZ33_18040	COG1216	Glycosyl transferase, family 2
LYZ33_18055	COG1695	Transcriptional regulator
LYZ33_18060	COG0351	phosphomethylpyrimidine kinase
LYZ33_18070	COG1621	beta-fructofuranosidase activity
LYZ33_18075	COG1263	PTS System
LYZ33_18075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LYZ33_18080	COG3711	transcriptional antiterminator
LYZ33_18090	COG1404	Belongs to the peptidase S8 family
LYZ33_18095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LYZ33_18100	COG0778	Nitroreductase
LYZ33_18105	COG0772	Belongs to the SEDS family
LYZ33_18115	COG0454	-acetyltransferase
LYZ33_18135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LYZ33_18140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LYZ33_18145	COG2261	transglycosylase associated protein
LYZ33_18150	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LYZ33_18160	COG2246	polysaccharide biosynthetic process
LYZ33_18165	COG1309	transcriptional regulator
LYZ33_18185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LYZ33_18190	COG2837	iron assimilation
LYZ33_18210	COG0583	DNA-binding transcription factor activity
LYZ33_18220	COG1346	cytolysis
LYZ33_18225	COG4895	conserved protein (DUF2196)
LYZ33_18230	COG0789	Transcriptional regulator
LYZ33_18235	COG5504	Zn-dependent protease
LYZ33_18240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LYZ33_18245	COG0346	lactoylglutathione lyase activity
LYZ33_18250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LYZ33_18255	COG1404	Belongs to the peptidase S8 family
LYZ33_18260	COG1442	glycosyl transferase family 8
LYZ33_18265	COG2357	RelA SpoT domain protein
LYZ33_18270	COG1575	Belongs to the MenA family. Type 1 subfamily
LYZ33_18285	COG1696	Membrane protein involved in D-alanine export
LYZ33_18295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LYZ33_18300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LYZ33_18305	COG1486	melibiose metabolic process
LYZ33_18310	COG1447	Phosphotransferase system cellobiose-specific component IIA
LYZ33_18315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LYZ33_18320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LYZ33_18325	COG3711	transcriptional antiterminator
LYZ33_18325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LYZ33_18335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_18340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LYZ33_18350	COG0640	Transcriptional regulator
LYZ33_18355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LYZ33_18360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LYZ33_18365	COG1447	Phosphotransferase system cellobiose-specific component IIA
LYZ33_18370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LYZ33_18375	COG2723	6-phospho-beta-galactosidase activity
LYZ33_18380	COG1940	carbohydrate kinase activity
LYZ33_18385	COG1482	cell wall glycoprotein biosynthetic process
LYZ33_18395	COG0753	catalase activity
LYZ33_18400	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LYZ33_18405	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LYZ33_18410	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LYZ33_18415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LYZ33_18420	COG4988	ABC transporter
LYZ33_18425	COG1294	oxidase, subunit
LYZ33_18430	COG1271	oxidase subunit
LYZ33_18435	COG3493	citrate carrier protein
LYZ33_18440	COG0726	polysaccharide deacetylase
LYZ33_18445	COG3842	ATPase activity
LYZ33_18450	COG2508	Transcriptional regulator
LYZ33_18455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LYZ33_18465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LYZ33_18480	COG4894	glucomannan catabolic process
LYZ33_18485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LYZ33_18490	COG0500	methyltransferase
LYZ33_18495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LYZ33_18510	COG0693	protein deglycase activity
LYZ33_18510	COG0753	catalase activity
LYZ33_18515	COG2851	Citrate transporter
LYZ33_18520	COG2273	Hydrolase Family 16
LYZ33_18525	COG3711	transcriptional antiterminator
LYZ33_18530	COG2270	Major facilitator Superfamily
LYZ33_18535	COG0513	Belongs to the DEAD box helicase family
LYZ33_18585	COG0697	spore germination
LYZ33_18590	COG0589	response to stress
LYZ33_18595	COG2723	6-phospho-beta-galactosidase activity
LYZ33_18600	COG1263	PTS System
LYZ33_18600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LYZ33_18600	COG2190	(PTS) system
LYZ33_18615	COG3507	Belongs to the glycosyl hydrolase 43 family
LYZ33_18640	COG0010	Belongs to the arginase family
LYZ33_18645	COG0833	amino acid
LYZ33_18650	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LYZ33_18655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LYZ33_18665	COG2390	Transcriptional regulator
LYZ33_18670	COG0561	phosphatase activity
LYZ33_18700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LYZ33_18705	COG5294	Protein conserved in bacteria
LYZ33_18710	COG0577	efflux transmembrane transporter activity
LYZ33_18715	COG1136	(ABC) transporter
LYZ33_18720	COG2205	protein histidine kinase activity
LYZ33_18725	COG0745	RESPONSE REGULATOR receiver
LYZ33_18740	COG1082	Xylose isomerase domain protein TIM barrel
LYZ33_18750	COG2814	Major facilitator Superfamily
LYZ33_18780	COG1349	DNA-binding transcription factor activity
LYZ33_18785	COG0667	Aldo Keto reductase
LYZ33_18790	COG2814	Major facilitator Superfamily
LYZ33_18805	COG1028	Short-chain dehydrogenase reductase Sdr
LYZ33_18810	COG2197	response regulator
LYZ33_18815	COG4585	Histidine kinase
LYZ33_18820	COG3239	Fatty acid desaturase
LYZ33_18825	COG1309	transcriptional regulator
LYZ33_18830	COG1012	belongs to the aldehyde dehydrogenase family
LYZ33_18835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LYZ33_18845	COG0640	Transcriptional regulator
LYZ33_18850	COG2814	Major facilitator Superfamily
LYZ33_18855	COG1714	RDD family
LYZ33_18865	COG0450	alkyl hydroperoxide reductase
LYZ33_18870	COG3634	alkyl hydroperoxide reductase activity
LYZ33_18875	COG3177	Filamentation induced by cAMP protein fic
LYZ33_18880	COG1113	amino acid transport
LYZ33_18890	COG2080	2 iron, 2 sulfur cluster binding
LYZ33_18905	COG2068	MobA-Related Protein
LYZ33_18910	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LYZ33_18955	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LYZ33_18960	COG0667	Aldo Keto reductase
LYZ33_18965	COG0456	acetyltransferase
LYZ33_18970	COG0457	Tetratricopeptide repeat
LYZ33_18975	COG0010	Belongs to the arginase family
LYZ33_18980	COG0833	amino acid
LYZ33_18985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LYZ33_18990	COG5658	integral membrane protein
LYZ33_18995	COG0640	Transcriptional regulator
LYZ33_19000	COG3829	transcription factor binding
LYZ33_19010	COG0488	(ABC) transporter
LYZ33_19025	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LYZ33_19035	COG0745	RESPONSE REGULATOR receiver
LYZ33_19040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LYZ33_19045	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LYZ33_19050	COG4853	Protein conserved in bacteria
LYZ33_19055	COG4863	YycH protein
LYZ33_19060	COG5002	protein histidine kinase activity
LYZ33_19065	COG0745	RESPONSE REGULATOR receiver
LYZ33_19095	COG0346	lactoylglutathione lyase activity
LYZ33_19100	COG0305	Participates in initiation and elongation during chromosome replication
LYZ33_19115	COG3093	addiction module antidote protein HigA
LYZ33_19120	COG0297	glycogen (starch) synthase activity
LYZ33_19130	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LYZ33_19135	COG0297	glycogen (starch) synthase activity
LYZ33_19145	COG2112	serine threonine protein kinase
LYZ33_19155	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LYZ33_19160	COG4241	membrane
LYZ33_19170	COG5577	PFAM Coat F domain
LYZ33_19175	COG1733	regulation of RNA biosynthetic process
LYZ33_19185	COG0697	spore germination
LYZ33_19190	COG1621	beta-fructofuranosidase activity
LYZ33_19195	COG1621	beta-fructofuranosidase activity
LYZ33_19200	COG1802	Transcriptional regulator
LYZ33_19205	COG2318	DinB family
LYZ33_19210	COG2211	Major facilitator Superfamily
LYZ33_19220	COG2197	response regulator
LYZ33_19225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LYZ33_19225	COG0512	Glutamine amidotransferase of anthranilate synthase
LYZ33_19230	COG0697	spore germination
LYZ33_19250	COG0778	Nitroreductase
LYZ33_19255	COG1846	Transcriptional regulator
LYZ33_19260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LYZ33_19265	COG1846	Transcriptional regulator
LYZ33_19270	COG2153	protein acetylation
LYZ33_19275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LYZ33_19280	COG0697	spore germination
LYZ33_19285	COG1331	Highly conserved protein containing a thioredoxin domain
LYZ33_19290	COG1266	CAAX protease self-immunity
LYZ33_19295	COG0477	Major facilitator Superfamily
LYZ33_19295	COG2814	Major facilitator Superfamily
LYZ33_19300	COG0346	lactoylglutathione lyase activity
LYZ33_19305	COG1609	Transcriptional regulator
LYZ33_19310	COG0708	Exodeoxyribonuclease III
LYZ33_19315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LYZ33_19320	COG2169	Transcriptional regulator
LYZ33_19330	COG0629	single-stranded DNA binding
LYZ33_19340	COG0012	GTP binding
LYZ33_19345	COG0243	molybdopterin cofactor binding
LYZ33_19350	COG4481	Protein conserved in bacteria
LYZ33_19355	COG3949	Membrane
LYZ33_19370	COG1475	DNA binding
LYZ33_19375	COG1192	Involved in chromosome partitioning
LYZ33_19400	COG1847	R3H domain protein
LYZ33_19405	COG0706	membrane insertase activity