locus-tag	class	description
UP17_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
UP17_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
UP17_00015	ENOG410848D	S4 domain protein YaaA
UP17_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
UP17_00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
UP17_00035	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
UP17_00070	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
UP17_00090	ENOG4105ZMH	deoxynucleoside kinase
UP17_00120	ENOG4105C6E	dna polymerase iii
UP17_00130	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
UP17_00140	ENOG41067KS	pro-sigma K processing
UP17_00175	ENOG4105CXN	decarboxylase
UP17_00180	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
UP17_00185	ENOG4105X0R	protein from nitrogen regulatory protein P-II
UP17_00190	ENOG4105XVJ	Protein of unknown function (DUF327)
UP17_00195	ENOG4105FA2	dna polymerase iii
UP17_00200	ENOG4105MA4	psp1 domain protein
UP17_00205	ENOG4105QD5	Involved in initiation control of chromosome replication (By similarity)
UP17_00210	ENOG41060K3	Methyltransferase
UP17_00215	ENOG4105VC4	domain protein
UP17_00220	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
UP17_00225	ENOG4105KRN	Transcriptional regulator, abrb family
UP17_00235	ENOG4105F8V	Hydrolase, tatD family
UP17_00240	ENOG41069ER	domain protein
UP17_00245	ENOG4105HVR	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity)
UP17_00250	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
UP17_00255	ENOG4105XFA	sporulation peptidase YabG
UP17_00260	ENOG4105W42	Veg protein
UP17_00270	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
UP17_00275	ENOG4105DFT	pur operon repressor
UP17_00280	ENOG4105KME	endoribonuclease L-psp
UP17_00285	ENOG4105K4W	Could be involved in septation (By similarity)
UP17_00290	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
UP17_00295	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
UP17_00305	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
UP17_00320	ENOG4108JA2	transcriptioN-repair coupling factor
UP17_00325	ENOG4108M14	stage v sporulation protein t
UP17_00335	ENOG4108IY2	MazG family
UP17_00340	ENOG41082I2	s4 domain protein
UP17_00345	ENOG4105VYY	sporulation protein yabp
UP17_00360	ENOG41060GV	RNA binding s1 domain protein
UP17_00390	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
UP17_00395	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
UP17_00405	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
UP17_00410	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
UP17_00415	ENOG4107U48	ppic-type peptidyL-prolyl cis-trans isomerase
UP17_00420	ENOG4105C6T	cysteine synthase
UP17_00425	ENOG4105EEI	dihydropteroate synthase
UP17_00430	ENOG4105KRF	dihydroneopterin aldolase
UP17_00435	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UP17_00445	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
UP17_00450	ENOG4105CRK	lysyL-tRNA synthetase
UP17_00535	ENOG4108Z0C	Uvrb UvrC protein
UP17_00540	ENOG41066A3	ATP guanido phosphotransferase
UP17_00550	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
UP17_00555	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
UP17_00560	ENOG4105CTP	PilT protein domain protein
UP17_00565	ENOG4108QHG	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
UP17_00570	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
UP17_00575	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
UP17_00585	ENOG4105D7W	serine acetyltransferase
UP17_00590	ENOG4105C8N	cysteinyl-tRNA synthetase
UP17_00600	ENOG4105C2N	RNA methyltransferase TrmH family group 3
UP17_00605	ENOG4105M0M	Tetracycline resistance protein
UP17_00610	ENOG4105QIV	RNA polymerase
UP17_00620	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
UP17_00630	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
UP17_00640	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
UP17_00645	ENOG4107Y49	methyltransferase
UP17_00650	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
UP17_00655	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
UP17_00660	ENOG4105XPM	ribosomal protein
UP17_00665	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
UP17_00670	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
UP17_00675	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
UP17_00690	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
UP17_00695	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
UP17_00700	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
UP17_00705	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UP17_00710	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
UP17_00715	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
UP17_00720	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
UP17_00725	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
UP17_00730	ENOG41082SA	50s ribosomal protein l29
UP17_00735	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
UP17_00745	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
UP17_00755	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
UP17_00760	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
UP17_00765	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
UP17_00770	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
UP17_00775	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
UP17_00780	ENOG4105VPB	50S ribosomal protein L30
UP17_00790	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
UP17_00800	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
UP17_00810	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UP17_00815	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
UP17_00820	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
UP17_00825	ENOG4108ZT0	50S ribosomal protein l17
UP17_00830	ENOG4108JJB	ABC transporter
UP17_00835	ENOG4108JJB	ABC transporter
UP17_00840	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
UP17_00850	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
UP17_00855	ENOG4108UJD	30S ribosomal protein S9
UP17_00875	ENOG4105D1F	ATP-binding protein
UP17_00890	ENOG4108NMV	polysaccharide deacetylase
UP17_00970	ENOG4105EMN	RNA polymerase sigma factor
UP17_00980	ENOG4105C8B	TIGR00159 family
UP17_00985	ENOG4107U5W	ybbr family
UP17_00990	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
UP17_00995	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
UP17_01000	ENOG4108ZMX	Domain of unknown function (DU1801)
UP17_01015	ENOG4105BZU	Histidine kinase
UP17_01025	ENOG4105BZ1	(ABC) transporter
UP17_01030	ENOG4105CPF	Cell wall formation (By similarity)
UP17_01060	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
UP17_01065	ENOG4105BZ8	glutamate synthase
UP17_01070	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
UP17_01090	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
UP17_01095	ENOG4105CBD	Diacylglycerol kinase
UP17_01100	ENOG4107SUZ	Sodium/hydrogen exchanger family
UP17_01110	ENOG4105C1Q	protoporphyrinogen oxidase
UP17_01120	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
UP17_01125	ENOG4105F38	ABC transporter, permease
UP17_01130	ENOG4108EG7	Binding-protein-dependent transport systems, inner membrane component
UP17_01135	ENOG4107RUE	extracellular solute-binding protein family 1
UP17_01140	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
UP17_01160	ENOG4108SU4	UPF0309 protein
UP17_01165	ENOG4105FDP	GntR family transcriptional regulator
UP17_01170	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
UP17_01175	ENOG4105CE4	GlcNAc 6-P deacetylase
UP17_01180	ENOG4105CI1	PTS System
UP17_01185	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
UP17_01190	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
UP17_01210	ENOG410650H	(LipO)protein
UP17_01215	ENOG4105DBE	peroxidase
UP17_01220	ENOG4107SJW	iron permease, FTR1
UP17_01235	ENOG4105C37	(CBS) domain
UP17_01240	ENOG4105BZU	Histidine kinase
UP17_01245	ENOG4105BZU	Histidine kinase
UP17_01250	ENOG4108MJI	response regulator
UP17_01290	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
UP17_01305	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
UP17_01330	ENOG4105CPF	Cell wall formation (By similarity)
UP17_01335	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
UP17_01345	ENOG4105C1J	atp-dependent rna helicase
UP17_01350	ENOG410905X	membrane-flanked domain protein
UP17_01355	ENOG4105CKV	Membrane
UP17_01365	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
UP17_01370	ENOG4108SGW	outer membrane lipoprotein-sorting protein-like protein
UP17_01385	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
UP17_01390	ENOG4107MMM	Anti-sigma-factor antagonist
UP17_01395	ENOG4105FUA	antagonist
UP17_01400	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
UP17_01405	ENOG4107SGM	protein serine threonine phosphatase
UP17_01410	ENOG4105WN5	stage II sporulation protein
UP17_01415	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
UP17_01425	ENOG41064BQ	Phosphatase
UP17_01435	ENOG410906U	SprT-like
UP17_01515	ENOG4105K8N	protein family UPF0079, ATPase
UP17_01520	ENOG41072GX	Peptidase M22 Glycoprotease
UP17_01525	ENOG410801F	ribosomal-protein-alanine acetyltransferase
UP17_01530	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
UP17_01535	ENOG4105C5H	ABC transporter
UP17_01540	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
UP17_01545	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
UP17_01555	ENOG4108TYN	CAAX amino terminal protease family protein
UP17_01565	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
UP17_01575	ENOG4105BZU	Histidine kinase
UP17_01580	ENOG4105BZU	Histidine kinase
UP17_01585	ENOG4105DUX	Transporter
UP17_01600	ENOG4105CMG	Carbohydrate kinase
UP17_01610	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
UP17_01630	ENOG4105CNI	cell division protein FtsW
UP17_01640	ENOG4105BZ4	penicillin-binding protein
UP17_01655	ENOG4108YYS	metal-dependent hydrolase (By similarity)
UP17_01685	ENOG4105WWK	YheO domain protein
UP17_01690	ENOG4105KME	endoribonuclease L-psp
UP17_01695	ENOG4105R9B	Major Facilitator
UP17_01725	ENOG4108NHD	germination protein
UP17_01730	ENOG4108Q8B	Spore germination protein
UP17_01750	ENOG4105U7G	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization (By similarity)
UP17_01755	ENOG4105C84	Histidine ammonia-lyase
UP17_01760	ENOG4108IQI	permease
UP17_01770	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
UP17_01785	ENOG4105DYB	Isoaspartyl dipeptidase
UP17_01800	ENOG4108IJ7	Glycine betaine
UP17_01820	ENOG4105DU0	nucleoside hydrolase
UP17_01840	ENOG4105EC2	ftsk spoIIIe
UP17_01855	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
UP17_01870	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
UP17_01875	ENOG4105C7N	Xanthine uracil vitamin C permease
UP17_01880	ENOG4105CID	antiterminator
UP17_01925	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
UP17_01950	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
UP17_01955	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
UP17_01960	ENOG4105C83	adenylosuccinate lyase
UP17_01970	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
UP17_01975	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
UP17_01995	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
UP17_02005	ENOG4105C12	Phosphoribosylglycinamide synthetase
UP17_02020	ENOG4108R5T	secreted protein
UP17_02025	ENOG4105KGF	protein, YerC YecD
UP17_02030	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
UP17_02035	ENOG4105C4R	Atp-dependent dna helicase
UP17_02040	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
UP17_02050	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
UP17_02055	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
UP17_02060	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
UP17_02070	ENOG4105CBD	Diacylglycerol kinase
UP17_02075	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
UP17_02085	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
UP17_02090	ENOG4108JYZ	YitT family
UP17_02095	ENOG4108QY0	Membrane
UP17_02110	ENOG4105CZ3	stage V sporulation protein ad
UP17_02115	ENOG41090VF	Stage v sporulation protein ac
UP17_02150	ENOG4105CDW	Resistance protein
UP17_02160	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
UP17_02170	ENOG4105KTB	nuclear export factor GLE1
UP17_02175	ENOG4108T5E	Copper resistance protein
UP17_02180	ENOG4105BZU	Histidine kinase
UP17_02190	ENOG410807C	QueT transporter
UP17_02195	ENOG4108UIN	ybak prolyl-trna synthetase associated region
UP17_02215	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
UP17_02220	ENOG4105BZU	Histidine kinase
UP17_02230	ENOG4105IIU	Aminopeptidase
UP17_02255	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
UP17_02260	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
UP17_02270	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
UP17_02275	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
UP17_02280	ENOG410749K	Uncharacterized protein conserved in bacteria (DUF2179)
UP17_02290	ENOG4105XN3	extracellular solute-binding protein family 1
UP17_02305	ENOG4105FKQ	transcriptional regulator
UP17_02320	ENOG4105CK5	oxidoreductase
UP17_02330	ENOG4105FE9	pseudouridine synthase
UP17_02340	ENOG4105CPC	Aldo Keto reductase
UP17_02360	ENOG4105C2J	ABC transporter
UP17_02365	ENOG4105CNN	ABC, transporter
UP17_02380	ENOG4105C0H	protease
UP17_02400	ENOG4105E2S	oxidase) subunit II
UP17_02410	ENOG4105CCU	oxidase (Subunit III)
UP17_02435	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
UP17_02440	ENOG4105CFH	Aspartokinase
UP17_02445	ENOG4107Y03	Nitroreductase
UP17_02455	ENOG4105BZ1	(ABC) transporter
UP17_02460	ENOG4105BZ1	(ABC) transporter
UP17_02475	ENOG4105D22	carbon starvation protein
UP17_02485	ENOG4105BZU	Histidine kinase
UP17_02500	ENOG4105DY9	regulatoR
UP17_02505	ENOG4105CYC	Transferase
UP17_02510	ENOG4105C02	permease
UP17_02515	ENOG4105C26	Dehydrogenase
UP17_02520	ENOG4105CK2	sodium dicarboxylate symporter
UP17_02525	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
UP17_02530	ENOG41069ER	domain protein
UP17_02535	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
UP17_02565	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
UP17_02570	ENOG4107XGZ	Hydrolase
UP17_02580	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
UP17_02585	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UP17_02595	ENOG4105C26	Dehydrogenase
UP17_02600	ENOG4108J2R	molybdopterin oxidoreductase
UP17_02605	ENOG4105CK7	Sodium proline symporter
UP17_02610	ENOG4105BZU	Histidine kinase
UP17_02615	ENOG4105FDU	atp-dependent rna helicase
UP17_02620	ENOG4108594	Permease of the drug metabolite transporter
UP17_02625	ENOG4105C28	cystathionine
UP17_02635	ENOG4108R6K	riboflavin synthase, subunit alpha
UP17_02655	ENOG4107U9T	Pfam:Ribonuclease_BN
UP17_02665	ENOG4107S91	Sodium hydrogen exchanger
UP17_02670	ENOG4105NCW	Trka-c domain protein
UP17_02690	ENOG4108KK1	membrane protein AbrB duplication
UP17_02695	ENOG4105E14	MotA TolQ exbB proton channel
UP17_02700	ENOG4105ER2	Ompa motb domain protein
UP17_02705	ENOG4107RKG	DJ-1/PfpI family
UP17_02710	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
UP17_02720	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
UP17_02725	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
UP17_02730	ENOG41068PA	UPF0435 protein
UP17_02740	ENOG4107U9T	Pfam:Ribonuclease_BN
UP17_02750	ENOG4105C59	p-type ATPase
UP17_02755	ENOG4108ISG	Major Facilitator
UP17_02760	ENOG4105UPD	Calcium Proton
UP17_02805	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
UP17_02815	ENOG4108W15	Protein of unknown function (DUF1456)
UP17_02830	ENOG4105EXW	epimerase dehydratase
UP17_02845	ENOG4105CS9	pantothenic acid kinase
UP17_02875	ENOG4105KVH	Transcriptional regulator
UP17_02880	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
UP17_02895	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_02905	ENOG4105DZ1	carboxypeptidase
UP17_02910	ENOG41069DP	small acid-soluble spore protein
UP17_02915	ENOG4105DWT	malate dehydrogenase (quinone)
UP17_02925	ENOG4105DQ6	Transposase
UP17_02930	ENOG4105WD1	Membrane
UP17_02990	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_02995	ENOG4105IIP	Membrane
UP17_03005	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_03020	ENOG4105CHR	reductase
UP17_03025	ENOG4107XNU	peptidase
UP17_03045	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_03090	ENOG41082BM	Transcriptional regulator, arsr family
UP17_03110	ENOG4105DQ6	Transposase
UP17_03125	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_03145	ENOG4105DQ6	Transposase
UP17_03165	ENOG4105ED2	Beta-lactamase
UP17_03175	ENOG41082W1	Cupin 2, conserved barrel domain protein
UP17_03185	ENOG4105EMU	Dehydrogenase
UP17_03195	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
UP17_03200	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_03210	ENOG4108U05	Transcriptional regulator
UP17_03215	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
UP17_03230	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_03255	ENOG4106R3P	AraC family transcriptional regulator
UP17_03260	ENOG4105C54	Major Facilitator superfamily
UP17_03265	ENOG4105C84	Histidine ammonia-lyase
UP17_03290	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_03295	ENOG4108Z5V	transcriptional regulator, merr family
UP17_03300	ENOG4108UQV	Membrane
UP17_03305	ENOG4105VFE	sira family
UP17_03310	ENOG4105DXI	Major Facilitator superfamily
UP17_03315	ENOG4108RWP	Major Facilitator Superfamily protein
UP17_03330	ENOG4108YZ9	Urea amidohydrolase subunit gamma
UP17_03340	ENOG4105CQM	Urea amidohydrolase subunit alpha
UP17_03345	ENOG4105HFU	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
UP17_03350	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
UP17_03355	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
UP17_03360	ENOG4105ICD	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
UP17_03385	ENOG4105C4Y	ABC transporter
UP17_03390	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
UP17_03395	ENOG4108I5D	sulfate abc transporter
UP17_03400	ENOG4106IQC	argininosuccinate lyase
UP17_03415	ENOG4105E1V	na solute symporter
UP17_03425	ENOG4105C85	amino acid
UP17_03435	ENOG4107QTZ	amino acid
UP17_03440	ENOG4105DNP	FAD linked oxidase domain protein
UP17_03470	ENOG4105DA5	(ABC) transporter
UP17_03480	ENOG4105DA5	(ABC) transporter
UP17_03535	ENOG4105EBR	Carboxylesterase
UP17_03560	ENOG4105C19	ABC transporter
UP17_03565	ENOG4108HVR	ABC transporter, permease
UP17_03580	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
UP17_03590	ENOG4105CDA	abc transporter atp-binding protein
UP17_03595	ENOG4105DRP	amino acid AbC transporter
UP17_03620	ENOG4105CHM	Aminotransferase
UP17_03650	ENOG4105K7K	Transcriptional regulator
UP17_03665	ENOG4105CZM	Major Facilitator
UP17_03685	ENOG4105JZI	cytochrome P450
UP17_03695	ENOG4106F5Q	Membrane
UP17_03700	ENOG4106PMH	Extracellular solute-binding protein family 3
UP17_03705	ENOG4105E5Q	amino acid AbC transporter
UP17_03710	ENOG4105CDA	abc transporter atp-binding protein
UP17_03720	ENOG4105CMU	LysR family (Transcriptional regulator
UP17_03740	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_03745	ENOG4105CHU	acetyl-coa acetyltransferase
UP17_03760	ENOG4105ECP	epimerase
UP17_03765	ENOG410902V	Modulates RecA activity (By similarity)
UP17_03775	ENOG4105XHU	Acid-soluble spore protein K
UP17_03785	ENOG41067AE	Membrane-bound metal-dependent hydrolase
UP17_03790	ENOG4105CEN	a g-specific adenine glycosylase
UP17_03795	ENOG4106BXE	
UP17_03800	ENOG4105CAN	Short-chain dehydrogenase reductase Sdr
UP17_03815	ENOG4105EVI	UPF0374 protein
UP17_03820	ENOG4105BZ1	(ABC) transporter
UP17_03835	ENOG4105CS1	NAD(P)H quinone oxidoreductase
UP17_03840	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_03845	ENOG4105CW7	secretion protein, HlyD family
UP17_03855	ENOG4107NBY	Membrane
UP17_03860	ENOG4105CBC	glutamate synthase
UP17_03865	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
UP17_03875	ENOG4108IUW	ABC transporter
UP17_03890	ENOG4108S4H	thioesterase Superfamily protein
UP17_03905	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UP17_03915	ENOG4105C5I	Dehydrogenase
UP17_03920	ENOG4105G5W	regulator Fur family
UP17_03925	ENOG4105TUA	UPF0295 protein
UP17_04060	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
UP17_04070	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
UP17_04080	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
UP17_04105	ENOG4105U0R	haloacid dehalogenase-like hydrolase
UP17_04110	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
UP17_04150	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
UP17_04165	ENOG41090UD	(LipO)protein
UP17_04220	ENOG4105EEQ	Na H antiporter
UP17_04225	ENOG4105E1K	spore germination protein
UP17_04240	ENOG4108Q8B	Spore germination protein
UP17_04245	ENOG4108Q8B	Spore germination protein
UP17_04250	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
UP17_04260	ENOG4105K6V	RNA polymerase
UP17_04270	ENOG4105PAD	Hydrolase
UP17_04275	ENOG4105CSH	Transporter
UP17_04285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
UP17_04310	ENOG4105J7D	transcriptional regulator
UP17_04315	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_04345	ENOG4105C87	Aminotransferase class I and II
UP17_04355	ENOG4108IQI	permease
UP17_04360	ENOG4105KME	endoribonuclease L-psp
UP17_04365	ENOG4105K6H	D-cysteine desulfhydrase
UP17_04375	ENOG4105CJW	magnesium transporter
UP17_04380	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
UP17_04385	ENOG4105ME7	Membrane
UP17_04405	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
UP17_04410	ENOG4108QY0	Membrane
UP17_04420	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
UP17_04425	ENOG4108DBC	nitroreductase
UP17_04450	ENOG4107QTZ	amino acid
UP17_04455	ENOG4105CYN	Serine protein kinase
UP17_04475	ENOG4105DJ2	Major Facilitator Superfamily
UP17_04480	ENOG41073TP	transcriptional regulator
UP17_04490	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
UP17_04510	ENOG4105C0X	amino acid
UP17_04520	ENOG4105CSC	Glucose uptake protein
UP17_04525	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
UP17_04560	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
UP17_04570	ENOG4107RA9	decarboxylase
UP17_04590	ENOG4108PJD	permease
UP17_04595	ENOG4108VX5	3-methyladenine DNA glycosylase
UP17_04600	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_04605	ENOG4105II7	pyrroline-5-carboxylate reductase
UP17_04610	ENOG4105CQB	FAD linked oxidase domain protein
UP17_04615	ENOG4105DCF	alanine dehydrogenase
UP17_04620	ENOG4105EU9	
UP17_04625	ENOG4108K8K	Transcriptional regulator
UP17_04630	ENOG4105CJ3	phosphate transporter
UP17_04635	ENOG4107GRR	phosphate transport regulator
UP17_04640	ENOG4105CJ3	phosphate transporter
UP17_04650	ENOG4107BMA	Transglycosylase associated protein
UP17_04655	ENOG4108YBP	pseudouridine synthase
UP17_04675	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
UP17_04705	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
UP17_04725	ENOG4105DTQ	mandelate racemase muconate lactonizing
UP17_04730	ENOG4108K88	Membrane
UP17_04735	ENOG4105ED1	spovr family
UP17_04740	ENOG41082YX	Transcriptional regulator, arsr family
UP17_04745	ENOG4107R5R	arsenical pump membrane protein
UP17_04750	ENOG4108UXE	Protein tyrosine phosphatase
UP17_04760	ENOG4105DQ6	Transposase
UP17_04775	ENOG41080BT	SNARE associated Golgi
UP17_04780	ENOG4105EFI	regulatoR
UP17_04785	ENOG4105BZU	Histidine kinase
UP17_04810	ENOG4105FGV	Chromate
UP17_04815	ENOG4105CAH	Chromate
UP17_04820	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
UP17_04840	ENOG4105CUB	amino acid
UP17_04855	ENOG4105G9B	Transcriptional regulator
UP17_04865	ENOG4105C5R	Aminotransferase
UP17_04870	ENOG4105CD3	dihydroorotase
UP17_04890	ENOG4105DZS	Phenylacetate-CoA ligase
UP17_04905	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
UP17_04930	ENOG4105E39	Enoyl-CoA hydratase
UP17_04935	ENOG4105CGU	Enoyl-CoA hydratase
UP17_04940	ENOG4105C26	Dehydrogenase
UP17_04945	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
UP17_04950	ENOG4105CHU	acetyl-coa acetyltransferase
UP17_04955	ENOG4105E39	Enoyl-CoA hydratase
UP17_04965	ENOG4108Z0R	Transferase
UP17_04970	ENOG4105EA8	2-Nitropropane dioxygenase
UP17_04975	ENOG4107T5V	SNARE associated Golgi
UP17_04990	ENOG4105PGM	cation diffusion facilitator family transporter
UP17_04995	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_05000	ENOG4105BZU	Histidine kinase
UP17_05025	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
UP17_05030	ENOG4105E0C	molybdate abc transporter
UP17_05045	ENOG4105VEQ	Cold shock protein
UP17_05055	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
UP17_05060	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
UP17_05065	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
UP17_05070	ENOG4105CHH	sulfate transporter
UP17_05090	ENOG4105D4T	Citrate transporter
UP17_05100	ENOG4105C72	UPF0176 protein
UP17_05110	ENOG4108W0I	acetyltransferase
UP17_05120	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UP17_05135	ENOG4108REF	Sporulation integral membrane protein ytvi
UP17_05140	ENOG4105C37	(CBS) domain
UP17_05145	ENOG4108JYZ	YitT family
UP17_05155	ENOG4107T5V	SNARE associated Golgi
UP17_05160	ENOG4105C37	(CBS) domain
UP17_05165	ENOG4105BZU	Histidine kinase
UP17_05180	ENOG4105N67	Proton-coupled thiamine transporter YuaJ
UP17_05190	ENOG4105BZ4	penicillin-binding protein
UP17_05200	ENOG4105DYB	Isoaspartyl dipeptidase
UP17_05215	ENOG4105CPP	Dehydrogenase, E1 component
UP17_05220	ENOG4105C7S	Dehydrogenase
UP17_05240	ENOG4105CIH	Imidazole acetol-phosphate transaminase
UP17_05265	ENOG4105K8R	UPF0145 protein
UP17_05270	ENOG4107VGR	Catalase
UP17_05285	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
UP17_05305	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
UP17_05310	ENOG4107RF6	penicillin-binding protein
UP17_05325	ENOG4105BZ1	(ABC) transporter
UP17_05330	ENOG4105BZ1	(ABC) transporter
UP17_05335	ENOG4105NRA	50s ribosomal protein l31 type b
UP17_05340	ENOG4105C28	cystathionine
UP17_05345	ENOG4105C28	cystathionine
UP17_05350	ENOG4105C9Q	fumarate hydratase class II
UP17_05400	ENOG410839P	
UP17_05405	ENOG410839P	
UP17_05425	ENOG4105WZB	UPF0342 protein
UP17_05460	ENOG4107TUM	Amidinotransferase
UP17_05465	ENOG4105CEY	Amp-dependent synthetase and ligase
UP17_05470	ENOG4105CGU	Enoyl-CoA hydratase
UP17_05490	ENOG4105C6T	cysteine synthase
UP17_05500	ENOG4107VRP	DNA repair exonuclease
UP17_05505	ENOG4106D4I	domain protein
UP17_05515	ENOG4105E0A	ABC, transporter
UP17_05525	ENOG4105EQI	Metal Dependent Phosphohydrolase
UP17_05535	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
UP17_05565	ENOG41088ZC	Negative regulator of protease production and sporulation (By similarity)
UP17_05580	ENOG4105NBU	tryptophan transport protein
UP17_05585	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
UP17_05590	ENOG4105K59	histidine triad (HIT) protein
UP17_05620	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
UP17_05625	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
UP17_05630	ENOG4107TTW	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
UP17_05640	ENOG4108RQ5	Beta-lactamase domain-containing protein
UP17_05645	ENOG4105DF9	Lipoate-protein, ligase
UP17_05650	ENOG4105CEY	Amp-dependent synthetase and ligase
UP17_05665	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
UP17_05670	ENOG4107AYK	membrAne
UP17_05680	ENOG4105XVF	Competence transcription factor
UP17_05685	ENOG41060YP	
UP17_05705	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
UP17_05750	ENOG4105CEY	Amp-dependent synthetase and ligase
UP17_05755	ENOG4105DCM	major facilitator superfamily
UP17_05765	ENOG4105YHS	UPF0344 protein
UP17_05775	ENOG4105CAQ	asparagine synthetase
UP17_05785	ENOG4107FKK	extracellular solute-binding protein family 1
UP17_05790	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
UP17_05800	ENOG4105FKQ	transcriptional regulator
UP17_05815	ENOG4108VPT	UPF0234 protein
UP17_05820	ENOG4105EPR	degv family
UP17_05825	ENOG4107AYK	membrAne
UP17_05830	ENOG41073B9	
UP17_05835	ENOG4108KP7	hydrolase
UP17_05840	ENOG4108MXZ	Esterase
UP17_05845	ENOG4105VG1	fes assembly suf system protein
UP17_05850	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
UP17_05855	ENOG4107V6Q	Cyclic nucleotide-binding domain
UP17_05860	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
UP17_05865	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
UP17_05870	ENOG4105CAS	nag kinase
UP17_05880	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
UP17_05890	ENOG4105DBV	ornithine carbamoyltransferase
UP17_05905	ENOG4105ERH	Fumarylacetoacetate hydrolase
UP17_05920	ENOG4105MSY	salicylate hydroxylase
UP17_05925	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
UP17_05955	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
UP17_05960	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
UP17_05970	ENOG4108KU1	UPF0736 protein
UP17_05975	ENOG4105C31	Tryptophanyl-tRNA synthetase
UP17_06000	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
UP17_06005	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
UP17_06010	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
UP17_06020	ENOG4105DPN	Oligoendopeptidase f
UP17_06030	ENOG4105T58	Dithiol-disulfide isomerase
UP17_06035	ENOG4108Z18	K06886 hemoglobin
UP17_06040	ENOG4105E4C	Lytic transglycosylase catalytic
UP17_06045	ENOG4105MIX	Adenylate cyclase
UP17_06055	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
UP17_06060	ENOG4105EMS	pseudouridine synthase
UP17_06065	ENOG4107S1Q	Phosphatase
UP17_06070	ENOG4105CJW	magnesium transporter
UP17_06075	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
UP17_06115	ENOG41090VF	Stage v sporulation protein ac
UP17_06120	ENOG4105CZ3	stage V sporulation protein ad
UP17_06140	ENOG4105ENA	helicase
UP17_06165	ENOG4108ZMI	UPF0477 protein
UP17_06175	ENOG4108W5N	phosphatidylglycerophosphatase a
UP17_06195	ENOG4108Z0Z	intracellular protease Pfpi family
UP17_06200	ENOG4105H67	Protein of unknown function (DUF421)
UP17_06225	ENOG4105SFS	phosphoesterase RecJ domain protein
UP17_06230	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
UP17_06235	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_06265	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
UP17_06270	ENOG4105C5I	Dehydrogenase
UP17_06275	ENOG4105C2C	drug resistance transporter, Bcr CflA
UP17_06285	ENOG4105EE0	oxidoreductase
UP17_06295	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
UP17_06300	ENOG4105CS2	ec 3.2.1.21
UP17_06305	ENOG4105CHH	sulfate transporter
UP17_06315	ENOG4105EBR	Carboxylesterase
UP17_06325	ENOG4105C85	amino acid
UP17_06330	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
UP17_06335	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
UP17_06340	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
UP17_06345	ENOG4108I5D	sulfate abc transporter
UP17_06350	ENOG4105ECW	sulfate abc transporter
UP17_06380	ENOG4108N2V	aldose 1-epimerase
UP17_06385	ENOG4105D5Q	Arginine ornithine antiporter
UP17_06405	ENOG4105VEQ	Cold shock protein
UP17_06420	ENOG4105C26	Dehydrogenase
UP17_06425	ENOG41079KZ	Major Facilitator Superfamily
UP17_06430	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
UP17_06435	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
UP17_06440	ENOG4105DWF	phosphomethylpyrimidine kinase
UP17_06450	ENOG4105ETU	transcriptional activator (TenA
UP17_06465	ENOG4107TCE	N-acetyltransferase
UP17_06490	ENOG4108S4H	thioesterase Superfamily protein
UP17_06495	ENOG4106I4J	membrane
UP17_06505	ENOG4108JQ7	(ABC) transporter
UP17_06510	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
UP17_06515	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UP17_06530	ENOG4105DER	m42 family
UP17_06535	ENOG410606W	general stress protein
UP17_06545	ENOG4105D9M	gamma-glutamylcysteine synthetase
UP17_06580	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
UP17_06585	ENOG4105DVE	abc transporter atp-binding protein
UP17_06600	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
UP17_06615	ENOG4108MRH	transcriptional regulatory protein
UP17_06620	ENOG4105C6K	Malic enzyme
UP17_06625	ENOG4107TT2	Auxin Efflux Carrier
UP17_06630	ENOG4105DFD	Na H antiporter
UP17_06635	ENOG4105CNI	cell division protein FtsW
UP17_06650	ENOG4107TS3	membrane protein, TerC
UP17_06655	ENOG4108WZW	RNA polymerase sigma
UP17_06675	ENOG4105BZU	Histidine kinase
UP17_06715	ENOG4108TGC	Acyltransferase
UP17_06720	ENOG4105BZU	Histidine kinase
UP17_06735	ENOG4105EU0	Major facilitator Superfamily
UP17_06740	ENOG4105BZU	Histidine kinase
UP17_06745	ENOG41090MY	MarR family Transcriptional regulator
UP17_06755	ENOG4108K88	Membrane
UP17_06775	ENOG4107Y9E	nuclease
UP17_06780	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
UP17_06785	ENOG4105C4B	ABC transporter, permease
UP17_06790	ENOG4105KRI	phosphocarrier protein (HPr
UP17_06795	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
UP17_06800	ENOG4105CHR	reductase
UP17_06805	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
UP17_06815	ENOG4105CHM	Aminotransferase
UP17_06820	ENOG4105D7N	magnesium and cobalt transport protein CorA
UP17_06835	ENOG4107R88	Chemotaxis protein (CheV)
UP17_06865	ENOG4107QWE	)-transporter
UP17_06870	ENOG4105EPM	Diguanylate phosphodiesterase
UP17_06895	ENOG4107IN1	Protein of unknown function (DUF1797)
UP17_06905	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_06915	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
UP17_06920	ENOG4105CH2	amidohydrolase
UP17_06925	ENOG4107ZYR	domain protein
UP17_06930	ENOG4105CN5	Metallo-Beta-Lactamase
UP17_06935	ENOG4106EHS	UPF0356 protein
UP17_06940	ENOG4108X4Q	Hydrolase
UP17_06960	ENOG4105CPP	Dehydrogenase, E1 component
UP17_06965	ENOG4105C7S	Dehydrogenase
UP17_06990	ENOG4105CXN	decarboxylase
UP17_06995	ENOG4105EA8	2-Nitropropane dioxygenase
UP17_07000	ENOG4105WBI	UPF0223 protein
UP17_07005	ENOG4105CRQ	synthase (Component I)
UP17_07010	ENOG4105DDQ	anthranilate synthase
UP17_07015	ENOG4108I0Q	anthranilate phosphoribosyltransferase
UP17_07020	ENOG4105DK0	Indole-3-glycerol phosphate synthase
UP17_07050	ENOG4105ECY	inositol monophosphatase
UP17_07060	ENOG4105CI3	gtp-binding protein typa
UP17_07065	ENOG4105QA2	
UP17_07090	ENOG4108IAB	Phoh family
UP17_07105	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
UP17_07110	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
UP17_07115	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
UP17_07155	ENOG4106UY4	Inherit from COG: Scp-like extracellular
UP17_07195	ENOG4106H78	methyltransferase
UP17_07200	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
UP17_07205	ENOG4105H20	Sporulation integral membrane protein YlbJ
UP17_07210	ENOG4105D78	K07001 NTE family protein
UP17_07215	ENOG41063PX	domain protein
UP17_07225	ENOG4105CDE	UPF0348 protein
UP17_07230	ENOG4105KNH	Nucleic acid-binding protein
UP17_07240	ENOG4105E39	Enoyl-CoA hydratase
UP17_07265	ENOG41074B2	UPF0747 protein
UP17_07270	ENOG4108V6E	Cell division protein mraZ
UP17_07285	ENOG4105CJN	penicillin-binding protein
UP17_07295	ENOG4105CJN	penicillin-binding protein
UP17_07300	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
UP17_07305	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
UP17_07310	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
UP17_07315	ENOG4105CNI	cell division protein FtsW
UP17_07320	ENOG4105D4A	Cell wall formation (By similarity)
UP17_07325	ENOG4108W8M	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
UP17_07330	ENOG4108R2U	division initiation protein
UP17_07340	ENOG4105K67	small basic protein
UP17_07345	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
UP17_07350	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
UP17_07355	ENOG4108AWX	Sporulation factor SpoIIGA 
UP17_07360	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
UP17_07370	ENOG4105WR5	sporulation protein, YlmC YmxH family
UP17_07375	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
UP17_07380	ENOG4105DFA	alanine racemase domain protein
UP17_07385	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
UP17_07390	ENOG41067XK	integral membrane protein
UP17_07395	ENOG4105DBK	s4 domain protein
UP17_07410	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
UP17_07415	ENOG4105C34	Pseudouridine synthase
UP17_07420	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
UP17_07430	ENOG4105CXT	aspartate transcarbamylase
UP17_07440	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
UP17_07445	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
UP17_07450	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
UP17_07455	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
UP17_07465	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
UP17_07470	ENOG4105F23	Fibronectin-binding protein
UP17_07480	ENOG4105DSJ	YicC domain protein
UP17_07490	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
UP17_07500	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
UP17_07505	ENOG4105C25	Primosomal protein n'
UP17_07515	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
UP17_07520	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
UP17_07525	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
UP17_07530	ENOG4108ZF3	Phosphatase
UP17_07535	ENOG4105D9P	serine threonine protein kinase
UP17_07540	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
UP17_07545	ENOG4105DJV	ribulose-phosphate 3-epimerase
UP17_07550	ENOG4105FJ0	thiamine
UP17_07560	ENOG4105VB9	50S ribosomal protein l28
UP17_07565	ENOG4108ZAA	Alkaline-shock protein
UP17_07570	ENOG4105DP4	dak2 domain fusion protein ylov
UP17_07580	ENOG4105EJQ	L-serine dehydratase
UP17_07585	ENOG4105CB5	ATP-dependent DNA helicase recG
UP17_07590	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
UP17_07600	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
UP17_07605	ENOG4105CHR	reductase
UP17_07610	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
UP17_07615	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
UP17_07620	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
UP17_07625	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
UP17_07640	ENOG4105K5M	30s ribosomal protein S16
UP17_07645	ENOG4105VB6	UPF0109 protein
UP17_07655	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
UP17_07660	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
UP17_07665	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
UP17_07675	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
UP17_07680	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
UP17_07705	ENOG4105D00	flagellar biosynthetic protein flhB
UP17_07710	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
UP17_07715	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
UP17_07720	ENOG4105C79	DNA protecting protein DprA
UP17_07725	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
UP17_07730	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
UP17_07735	ENOG4108HE4	integrase family
UP17_07745	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
UP17_07750	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
UP17_07755	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
UP17_07760	ENOG4108ZC9	flagellar basal-body rod protein flgc
UP17_07765	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
UP17_07770	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
UP17_07775	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
UP17_07790	ENOG4106YF4	Flagellar biosynthesis chaperone
UP17_07805	ENOG410822I	Flagellar hook capping protein
UP17_07815	ENOG4105BZE	flagellar hook protein, FlgE
UP17_07820	ENOG41068WV	flagellar FlbD family protein
UP17_07830	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
UP17_07835	ENOG4105DD5	Flagellar motor switch protein
UP17_07840	ENOG4107YTP	response regulator receiver protein
UP17_07850	ENOG4105CN7	Flagellar biosynthetic protein FliP
UP17_07855	ENOG4105VS8	Flagellar biosynthetic protein fliq
UP17_07860	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
UP17_07865	ENOG4105D00	flagellar biosynthetic protein flhB
UP17_07870	ENOG4105D7B	Flagellar biosynthesis protein flha
UP17_07875	ENOG4105FZW	flagellar biosynthesis regulator FlhF
UP17_07885	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
UP17_07890	ENOG4105CBS	Chea signal transduction histidine kinase
UP17_07895	ENOG4108V3W	Chemotaxis protein, CheW
UP17_07905	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
UP17_07910	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
UP17_07925	ENOG4105CE9	30S ribosomal protein S2
UP17_07945	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
UP17_07950	ENOG4105KNE	Phosphatidate cytidylyltransferase
UP17_07960	ENOG4105DZP	Membrane-associated zinc metalloprotease
UP17_07970	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
UP17_07975	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
UP17_07980	ENOG4105CHV	Transcription elongation factor NusA
UP17_07985	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
UP17_07990	ENOG4105VHM	ribosomal protein
UP17_07995	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
UP17_08000	ENOG4105W7A	Protein of unknown function (DUF503)
UP17_08005	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
UP17_08010	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
UP17_08015	ENOG4105DTN	riboflavin biosynthesis protein ribF
UP17_08025	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
UP17_08040	ENOG4105C1V	Peptidase, M16
UP17_08050	ENOG4105E35	Dipicolinate synthase subunit A
UP17_08055	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
UP17_08060	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
UP17_08070	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
UP17_08080	ENOG4105CVQ	ATP-dependent Clp protease, proteolytic subunit
UP17_08090	ENOG4105CNU	cell division protein FtsK
UP17_08100	ENOG4105FDP	GntR family transcriptional regulator
UP17_08105	ENOG4105DIH	basic membrane
UP17_08110	ENOG4108JQ9	ABC transporter
UP17_08115	ENOG4105UIB	(ABC) transporter
UP17_08135	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
UP17_08140	ENOG4105XZV	Protein of unknown function (DUF3243)
UP17_08155	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
UP17_08160	ENOG4105CEV	competence damage-inducible protein
UP17_08170	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
UP17_08180	ENOG4105D48	metallophosphoesterase
UP17_08185	ENOG4105MCT	stage V sporulation protein S
UP17_08195	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
UP17_08200	ENOG4105DQU	oxidoreductase, subunit beta
UP17_08210	ENOG4105CPQ	Dehydrogenase
UP17_08215	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
UP17_08240	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
UP17_08245	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
UP17_08255	ENOG4105EPD	Oligopeptide transporter, Opt family
UP17_08270	ENOG4105CAQ	asparagine synthetase
UP17_08275	ENOG4108X79	transcriptional regulator
UP17_08280	ENOG4105VZJ	PTS System
UP17_08285	ENOG4105CK1	PTS System
UP17_08290	ENOG4105VCP	PTS System
UP17_08295	ENOG4105F8D	glycoside hydrolase family 4
UP17_08320	ENOG4105DQ6	Transposase
UP17_08360	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
UP17_08365	ENOG4106F1P	AAA ATPase, central domain protein
UP17_08370	ENOG4105EN6	Membrane
UP17_08375	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
UP17_08380	ENOG4105CXI	aluminum resistance protein
UP17_08385	ENOG4105KV4	Transcriptional regulator
UP17_08390	ENOG4105C5F	glutamine synthetase
UP17_08400	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
UP17_08440	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_08450	ENOG4105JVQ	RNA Polymerase
UP17_08470	ENOG4105CJ1	ABC, transporter
UP17_08485	ENOG4105C19	ABC transporter
UP17_08500	ENOG4105BZU	Histidine kinase
UP17_08520	ENOG4105C5Y	PTS System
UP17_08530	ENOG4105D7K	pfkb domain protein
UP17_08535	ENOG4105C5Y	PTS System
UP17_08550	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
UP17_08560	ENOG4108QY0	Membrane
UP17_08570	ENOG4105DQ6	Transposase
UP17_08625	ENOG4105DQ6	Transposase
UP17_08660	ENOG4105DNP	FAD linked oxidase domain protein
UP17_08665	ENOG4105DQ6	Transposase
UP17_08695	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
UP17_08730	ENOG4105CHJ	isochorismatase hydrolase
UP17_08740	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
UP17_08745	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
UP17_08750	ENOG4105FBA	Phospholipase Carboxylesterase
UP17_08800	ENOG4105JVQ	RNA Polymerase
UP17_08825	ENOG4105CHR	reductase
UP17_08835	ENOG4105RHY	Pfam:UPF0157
UP17_08855	ENOG4105DFD	Na H antiporter
UP17_08865	ENOG4105DTQ	mandelate racemase muconate lactonizing
UP17_08905	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_08915	ENOG4107QHQ	amino acid
UP17_08925	ENOG4108KPW	sugar kinase
UP17_08930	ENOG4105FDP	GntR family transcriptional regulator
UP17_08975	ENOG4105DQ6	Transposase
UP17_08990	ENOG4105HDK	L-asparaginase
UP17_09000	ENOG4105ERH	Fumarylacetoacetate hydrolase
UP17_09010	ENOG4107TS3	membrane protein, TerC
UP17_09015	ENOG4108W2Y	isochorismatase
UP17_09045	ENOG4107Y9U	Membrane
UP17_09055	ENOG41088CQ	domain protein
UP17_09060	ENOG4105KNA	-acetyltransferase
UP17_09075	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
UP17_09125	ENOG4105C26	Dehydrogenase
UP17_09135	ENOG4105C26	Dehydrogenase
UP17_09140	ENOG4105CYW	agmatinase
UP17_09150	ENOG4107QM2	Aldo Keto reductase
UP17_09200	ENOG4105F1N	DNA alkylation repair
UP17_09215	ENOG4105C5Y	PTS System
UP17_09220	ENOG4105CG3	alpha amylase, catalytic region
UP17_09225	ENOG4107414	GntR family transcriptional regulator
UP17_09230	ENOG4107E54	Small Multidrug Resistance protein
UP17_09235	ENOG410814C	multidrug resistance protein
UP17_09290	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
UP17_09300	ENOG4108SVB	resolvase
UP17_09305	ENOG4105VPS	UPF0291 protein
UP17_09345	ENOG4105PGS	Spore coat protein
UP17_09360	ENOG4105K63	Thioredoxin
UP17_09365	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
UP17_09370	ENOG4108VGI	doxx family
UP17_09375	ENOG4107QIV	Cytochrome c biogenesis protein
UP17_09405	ENOG4105EYH	Exonuclease
UP17_09435	ENOG4105CBC	glutamate synthase
UP17_09440	ENOG4105CSV	Glutaminase
UP17_09460	ENOG4105D6E	homoserine dehydrogenase
UP17_09490	ENOG4108IQI	permease
UP17_09500	ENOG4105DTQ	mandelate racemase muconate lactonizing
UP17_09510	ENOG4108VSZ	Inherit from COG: ketosteroid isomerase-like protein
UP17_09535	ENOG4105XTG	Pfam:DUF156
UP17_09545	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
UP17_09555	ENOG41085GJ	domain protein
UP17_09560	ENOG4105VFE	sira family
UP17_09570	ENOG4107TPS	domain protein
UP17_09575	ENOG4105VFE	sira family
UP17_09580	ENOG41087NI	Sulfite exporter TauE/SafE
UP17_09630	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
UP17_09640	ENOG4108IUX	(ABC) transporter
UP17_09645	ENOG4105RHA	ABC transporter, permease
UP17_09660	ENOG4105VPX	protein, conserved in bacteria
UP17_09665	ENOG410681U	heavy metal transport detoxification protein
UP17_09670	ENOG4105C59	p-type ATPase
UP17_09705	ENOG4105DGI	Alkaline phosphatase
UP17_09710	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
UP17_09715	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
UP17_09725	ENOG4105C85	amino acid
UP17_09735	ENOG4107STF	Involved in phosphonate degradation (By similarity)
UP17_09745	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UP17_09760	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
UP17_09775	ENOG41082BV	acetyltransferase
UP17_09780	ENOG4108U05	Transcriptional regulator
UP17_09785	ENOG4105BZ1	(ABC) transporter
UP17_09795	ENOG4105K56	Transcriptional regulator
UP17_09805	ENOG4105CPP	Dehydrogenase, E1 component
UP17_09835	ENOG4105SX7	Transporter
UP17_09850	ENOG4105IQ5	FAD linked oxidase domain protein
UP17_09870	ENOG4105CGP	Urocanate hydratase
UP17_09880	ENOG4108I5G	Major Facilitator superfamily
UP17_09895	ENOG4105E7W	lamb ycsf family protein
UP17_09900	ENOG4105C5A	transporter
UP17_09905	ENOG4105CFM	UPF0317 protein
UP17_09910	ENOG4105P4J	Allophanate hydrolase, subunit 1
UP17_09925	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
UP17_09965	ENOG4105WH1	Two component transcriptional regulator luxr family
UP17_09975	ENOG4105BZU	Histidine kinase
UP17_09980	ENOG4107258	Transcriptional regulator
UP17_09995	ENOG4105N14	lysine exporter protein LysE YggA
UP17_10000	ENOG4108NGU	Transcriptional regulator
UP17_10010	ENOG4108V5C	ABC transporter
UP17_10015	ENOG4105EHG	Permease protein
UP17_10020	ENOG4105DQ5	transport system permease protein
UP17_10050	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
UP17_10060	ENOG41088SP	formiminoglutamate hydrolase
UP17_10065	ENOG4105D6U	Sodium Glutamate Symporter
UP17_10070	ENOG4108RAV	Conserved protein
UP17_10080	ENOG410667J	hydrolase
UP17_10085	ENOG4105R9B	Major Facilitator
UP17_10115	ENOG41067TZ	transcriptional regulator, MarR family
UP17_10135	ENOG4105DUM	transcriptional regulator, lysR family
UP17_10145	ENOG4105DQ6	Transposase
UP17_10150	ENOG4105CEY	Amp-dependent synthetase and ligase
UP17_10160	ENOG4105DJB	Major Facilitator Superfamily
UP17_10175	ENOG4105CHR	reductase
UP17_10185	ENOG4105DJB	Major Facilitator Superfamily
UP17_10195	ENOG4107RSM	transcriptional regulator
UP17_10200	ENOG4108R85	Short chain dehydrogenase
UP17_10210	ENOG4108W6C	Dehydrogenase
UP17_10215	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_10225	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
UP17_10235	ENOG4108HNZ	carboxyl transferase
UP17_10240	ENOG4105CMN	Methylmalonyl-coA mutase
UP17_10245	ENOG4105D5P	Methylmalonyl-coA mutase
UP17_10255	ENOG4105CHU	acetyl-coa acetyltransferase
UP17_10265	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
UP17_10280	ENOG4105E1K	spore germination protein
UP17_10285	ENOG4108B31	Spore germination protein
UP17_10315	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
UP17_10320	ENOG4105E98	transcriptional regulator DeoR family
UP17_10325	ENOG410667J	hydrolase
UP17_10330	ENOG4105KPY	Small multidrug resistance protein
UP17_10335	ENOG4105KPY	Small multidrug resistance protein
UP17_10360	ENOG4105DUM	transcriptional regulator, lysR family
UP17_10375	ENOG4108JJB	ABC transporter
UP17_10380	ENOG4108V4M	Cobalt abc transporter
UP17_10390	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
UP17_10400	ENOG4105E4R	Precorrin-3B C17-methyltransferase
UP17_10405	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
UP17_10410	ENOG4108JTQ	reductase
UP17_10415	ENOG41081F0	Precorrin-8x methylmutase
UP17_10420	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
UP17_10425	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
UP17_10430	ENOG4105DVK	Precorrin-2 c20-methyltransferase
UP17_10435	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
UP17_10440	ENOG4108P62	biosynthesis protein (CbiG)
UP17_10445	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
UP17_10460	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
UP17_10465	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
UP17_10470	ENOG4105K70	DNA-binding protein
UP17_10475	ENOG4105G0J	serine threonine protein kinase
UP17_10485	ENOG4105EFA	4-hydroxyphenylacetate
UP17_10535	ENOG4105D2S	major facilitator superfamily
UP17_10550	ENOG4105M4P	Tetr family transcriptional regulator
UP17_10565	ENOG4108IXY	short-chain dehydrogenase reductase
UP17_10575	ENOG4105ETU	transcriptional activator (TenA
UP17_10580	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
UP17_10590	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
UP17_10595	ENOG4108VEU	Thiamine monophosphate synthase
UP17_10600	ENOG41080HI	glycine oxidase
UP17_10605	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
UP17_10610	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
UP17_10615	ENOG4105D06	uba thif-type nad fad binding protein
UP17_10625	ENOG410746C	Acid-soluble spore protein O
UP17_10630	ENOG4108I0Z	Aconitate hydratase
UP17_10635	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UP17_10645	ENOG41067CD	Small, acid-soluble spore protein Tlp
UP17_10655	ENOG4105MI2	
UP17_10660	ENOG4105W8X	HesB YadR YfhF-family protein
UP17_10670	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
UP17_10675	ENOG4105K4P	CoA-binding domain protein
UP17_10680	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
UP17_10690	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
UP17_10715	ENOG4105EHZ	conserved protein UCP016719
UP17_10730	ENOG4105D9R	oxidoreductase
UP17_10765	ENOG4108NEV	two component transcriptional regulator, LytTR family
UP17_10775	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
UP17_10780	ENOG4108JPW	Aminotransferase
UP17_10840	ENOG4107TXC	Transcriptional regulator
UP17_10855	ENOG41069H0	dihydroorotase EC 3.5.2.3
UP17_10875	ENOG4105FDP	GntR family transcriptional regulator
UP17_10880	ENOG4105C6Z	Gluconate
UP17_10900	ENOG4107HP6	Transcriptional regulator
UP17_10915	ENOG4105CHR	reductase
UP17_10920	ENOG4105C7K	acetolactate synthase
UP17_10945	ENOG4108QJ2	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase
UP17_10955	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
UP17_10995	ENOG4105DQ6	Transposase
UP17_11030	ENOG4107SJW	iron permease, FTR1
UP17_11040	ENOG4105DUM	transcriptional regulator, lysR family
UP17_11045	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
UP17_11050	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
UP17_11060	ENOG4108B31	Spore germination protein
UP17_11090	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_11095	ENOG4105CEY	Amp-dependent synthetase and ligase
UP17_11100	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
UP17_11105	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
UP17_11110	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
UP17_11115	ENOG4105E39	Enoyl-CoA hydratase
UP17_11120	ENOG4107QX3	carboxylase
UP17_11135	ENOG4105DAP	Nicotinate phosphoribosyltransferase
UP17_11140	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
UP17_11145	ENOG4107S1E	Beta-lactamase
UP17_11235	ENOG4105DQ6	Transposase
UP17_11250	ENOG4108KAM	Transcriptional regulator
UP17_11255	ENOG4107EFR	Flavocytochrome c
UP17_11260	ENOG4105C7F	AcnD-accessory protein PrpF
UP17_11265	ENOG4108KAM	Transcriptional regulator
UP17_11275	ENOG4108ZDA	Sporulation protein YyaC
UP17_11285	ENOG4107RSM	transcriptional regulator
UP17_11325	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_11330	ENOG4105C2J	ABC transporter
UP17_11340	ENOG4105DQ6	Transposase
UP17_11380	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_11400	ENOG4106XGU	
UP17_11480	ENOG4105EW9	transcriptional regulator AsnC family
UP17_11485	ENOG4105F9V	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
UP17_11530	ENOG4105DWF	phosphomethylpyrimidine kinase
UP17_11550	ENOG4108R1P	
UP17_11560	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
UP17_11565	ENOG4105D2S	major facilitator superfamily
UP17_11575	ENOG4105KK4	UPF0060 membrane protein
UP17_11580	ENOG4105SX7	Transporter
UP17_11600	ENOG4105BZU	Histidine kinase
UP17_11660	ENOG4108IQI	permease
UP17_11690	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
UP17_11695	ENOG4106CAD	Protein of unknown function (DUF3311)
UP17_11700	ENOG4105E1V	na solute symporter
UP17_11725	ENOG4105DTQ	mandelate racemase muconate lactonizing
UP17_11740	ENOG4105E6M	Sulphatase-modifying factor protein
UP17_11785	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
UP17_11790	ENOG4105DQ6	Transposase
UP17_11810	ENOG4105DQ6	Transposase
UP17_11820	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
UP17_11825	ENOG4105FDT	acyl-CoA dehydrogenase
UP17_11835	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
UP17_11855	ENOG4105C85	amino acid
UP17_11865	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
UP17_11875	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
UP17_11880	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UP17_11885	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UP17_11890	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
UP17_11905	ENOG4105CIY	formyltetrahydrofolate deformylase
UP17_11920	ENOG4105EJQ	L-serine dehydratase
UP17_11925	ENOG4107RUY	(E1 component), alpha subunit
UP17_11935	ENOG4107QKR	Dehydrogenase
UP17_11945	ENOG4105CHR	reductase
UP17_11950	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
UP17_11960	ENOG41073R8	VanW family
UP17_11970	ENOG4108KF1	Membrane
UP17_11975	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
UP17_11980	ENOG4107ZTW	SNARE associated Golgi
UP17_11990	ENOG4108UZ3	Transporter
UP17_11995	ENOG4107XBN	GntR Family Transcriptional Regulator
UP17_12000	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
UP17_12035	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
UP17_12045	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
UP17_12050	ENOG4105CQB	FAD linked oxidase domain protein
UP17_12060	ENOG4105D38	putrescine abc transporter
UP17_12065	ENOG4105F38	ABC transporter, permease
UP17_12070	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
UP17_12085	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
UP17_12090	ENOG4105BZU	Histidine kinase
UP17_12095	ENOG4105CZ9	Domain of unknown function (DU1801)
UP17_12105	ENOG41082YX	Transcriptional regulator, arsr family
UP17_12135	ENOG4108XRC	Protein of unknown function (DUF458) 
UP17_12150	ENOG4105D8X	mechanosensitive ion channel
UP17_12175	ENOG4105C6Z	Gluconate
UP17_12180	ENOG4105BZW	Glycerate kinase
UP17_12190	ENOG4107VFR	oxidoreductase
UP17_12195	ENOG4108UB7	
UP17_12210	ENOG4105EK3	May be involved in the control of utilization of gamma- aminobutyric acid (By similarity)
UP17_12220	ENOG4105D5U	fad dependent oxidoreductase
UP17_12225	ENOG4108PVQ	transcriptional regulator
UP17_12245	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
UP17_12260	ENOG4105C28	cystathionine
UP17_12280	ENOG4105CZV	ABC transporter
UP17_12285	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
UP17_12330	ENOG4105DUM	transcriptional regulator, lysR family
UP17_12335	ENOG4105HMI	Membrane
UP17_12340	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
UP17_12345	ENOG4105R40	Glycine betaine carnitine choline
UP17_12350	ENOG4108HQR	Glycine betaine
UP17_12355	ENOG4105E90	ABC transporter
UP17_12360	ENOG4108IJ8	ABC transporter
UP17_12365	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_12380	ENOG41081YB	ApbE family
UP17_12390	ENOG4105BZU	Histidine kinase
UP17_12395	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_12415	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
UP17_12420	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
UP17_12425	ENOG4105II7	pyrroline-5-carboxylate reductase
UP17_12435	ENOG4105BZC	d-serine deaminase
UP17_12455	ENOG4105D5P	Methylmalonyl-coA mutase
UP17_12460	ENOG4105CMN	Methylmalonyl-coA mutase
UP17_12495	ENOG41087PP	glycosyltransferase MGT family
UP17_12520	ENOG4105C5H	ABC transporter
UP17_12525	ENOG4107G87	m6 family metalloprotease domain protein
UP17_12550	ENOG4105C26	Dehydrogenase
UP17_12560	ENOG4105CY2	Citrate transporter
UP17_12565	ENOG4105C0A	alcohol dehydrogenase
UP17_12570	ENOG4108JUB	Transcriptional regulator
UP17_12585	ENOG4105IIU	Aminopeptidase
UP17_12615	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
UP17_12665	ENOG4108TF4	von Willebrand factor, type A
UP17_12720	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
UP17_12725	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
UP17_12750	ENOG4105DQ6	Transposase
UP17_12765	ENOG4107T8Q	Glycosyl transferase (Group 1
UP17_12820	ENOG4105D0M	Protease HtpX homolog
UP17_12830	ENOG4105K4T	epimerase
UP17_12835	ENOG4107TB6	phosphoglycerate mutase
UP17_12845	ENOG4108U5N	UPF0316 protein
UP17_12855	ENOG4105CGK	Exodeoxyribonuclease III
UP17_12860	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
UP17_12865	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
UP17_12875	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
UP17_12880	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
UP17_12900	ENOG4108VCA	G U mismatch-specific DNA glycosylase
UP17_12925	ENOG410635A	Membrane
UP17_12930	ENOG4108Z73	Siroheme synthase
UP17_12935	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
UP17_12940	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
UP17_12950	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
UP17_12955	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
UP17_12960	ENOG4107RIQ	Sulfate adenylate transferase
UP17_12965	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
UP17_12970	ENOG4108UZX	fmn reductase
UP17_12985	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
UP17_12990	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
UP17_12995	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UP17_13005	ENOG4105CRQ	synthase (Component I)
UP17_13010	ENOG4105DEN	Luciferase family
UP17_13015	ENOG4105DEN	Luciferase family
UP17_13025	ENOG4105DPN	Oligoendopeptidase f
UP17_13055	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
UP17_13060	ENOG4105WH1	Two component transcriptional regulator luxr family
UP17_13070	ENOG4105CM2	brancheD-chain amino acid aminotransferase
UP17_13075	ENOG4105FCD	Major Facilitator
UP17_13080	ENOG4105C02	permease
UP17_13090	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
UP17_13115	ENOG4107TT2	Auxin Efflux Carrier
UP17_13120	ENOG4107Y2X	deaminase
UP17_13130	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
UP17_13145	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UP17_13150	ENOG4105C26	Dehydrogenase
UP17_13155	ENOG41068WN	
UP17_13170	ENOG4105E39	Enoyl-CoA hydratase
UP17_13175	ENOG4108JQ7	(ABC) transporter
UP17_13185	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UP17_13190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
UP17_13195	ENOG4108J59	Extracellular solute-binding protein, family 5
UP17_13215	ENOG4105K4I	Scp-like extracellular
UP17_13225	ENOG4107S1V	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
UP17_13230	ENOG4105ECB	domain protein
UP17_13275	ENOG4105C26	Dehydrogenase
UP17_13280	ENOG4108ZCF	integral membrane protein
UP17_13290	ENOG41068WN	
UP17_13295	ENOG4105CB2	alcohol dehydrogenase
UP17_13300	ENOG4107RIQ	Sulfate adenylate transferase
UP17_13305	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
UP17_13310	ENOG410635A	Membrane
UP17_13315	ENOG4105K64	Glycosyl transferase, family 2
UP17_13320	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
UP17_13350	ENOG4105EXW	epimerase dehydratase
UP17_13355	ENOG4105C5E	polysaccharide biosynthesis protein
UP17_13360	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
UP17_13365	ENOG4105BZ1	(ABC) transporter
UP17_13380	ENOG4105VRS	hydrolase family 18
UP17_13385	ENOG410904N	short-chain dehydrogenase reductase
UP17_13390	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
UP17_13395	ENOG4105XTG	Pfam:DUF156
UP17_13405	ENOG4108IJ0	Aspartate ammonia-lyase
UP17_13410	ENOG4105HDK	L-asparaginase
UP17_13430	ENOG4108J5H	Homocysteine s-methyltransferase
UP17_13435	ENOG4108IQI	permease
UP17_13440	ENOG4107XC4	flavin reductase domain protein, FMN-binding
UP17_13445	ENOG4105FBA	Phospholipase Carboxylesterase
UP17_13450	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
UP17_13480	ENOG4108X3M	OsmC Ohr family protein
UP17_13485	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_13490	ENOG4106AUC	UPF0180 protein
UP17_13515	ENOG4105KVH	Transcriptional regulator
UP17_13530	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
UP17_13535	ENOG41080XQ	Signal transduction protein with cbs domains
UP17_13545	ENOG4108TU7	Inherit from COG: (ABC) transporter
UP17_13550	ENOG4105CJ1	ABC, transporter
UP17_13560	ENOG4105C09	Bile acid
UP17_13565	ENOG4105D8G	Major Facilitator superfamily
UP17_13570	ENOG4105BZU	Histidine kinase
UP17_13575	ENOG4108JYZ	YitT family
UP17_13590	ENOG4105C9U	ATP-dependent DNA helicase RecQ
UP17_13595	ENOG41069ER	domain protein
UP17_13610	ENOG4105WEF	catalase
UP17_13615	ENOG4105QNR	S1 RNA binding domain protein
UP17_13625	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
UP17_13640	ENOG4105VRR	gCN5-related N-acetyltransferase
UP17_13645	ENOG4105EEM	helicase
UP17_13655	ENOG4105HHM	rdd domain containing protein
UP17_13660	ENOG4105C5H	ABC transporter
UP17_13685	ENOG4105CNN	ABC, transporter
UP17_13690	ENOG4105C2J	ABC transporter
UP17_13695	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
UP17_13700	ENOG4105E98	transcriptional regulator DeoR family
UP17_13705	ENOG4108HKT	sucrose-6-phosphate hydrolase
UP17_13710	ENOG4105EDQ	levansucrase EC 2.4.1.10
UP17_13715	ENOG4107FKK	extracellular solute-binding protein family 1
UP17_13720	ENOG4105EQD	regulatoR
UP17_13725	ENOG4105C2F	Histidine kinase
UP17_13740	ENOG4105DQ6	Transposase
UP17_13750	ENOG4105CBC	glutamate synthase
UP17_13765	ENOG4105DZ6	Band 7 protein
UP17_13815	ENOG4105DQ6	Transposase
UP17_13845	ENOG4105C26	Dehydrogenase
UP17_13860	ENOG4105C0A	alcohol dehydrogenase
UP17_13865	ENOG4105C26	Dehydrogenase
UP17_13880	ENOG4105E2A	Dehydrogenase
UP17_13885	ENOG4105PGS	Spore coat protein
UP17_13920	ENOG4105DZ6	Band 7 protein
UP17_13930	ENOG4105VKD	bioY protein
UP17_13940	ENOG4108UT2	hemolysin iii
UP17_13950	ENOG4105F0V	Cell wall hydrolase
UP17_13960	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
UP17_13970	ENOG4105DM4	PTS System
UP17_13975	ENOG4105DE4	1-phosphofructokinase
UP17_13980	ENOG4105E98	transcriptional regulator DeoR family
UP17_13985	ENOG4105C7S	Dehydrogenase
UP17_13990	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
UP17_13995	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
UP17_14015	ENOG4108RPX	mosc domain containing protein
UP17_14020	ENOG4105FDF	Could be involved in DNA repair (By similarity)
UP17_14025	ENOG4105DQE	DNA ligase
UP17_14035	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
UP17_14045	ENOG4108V2W	Carbonate dehydratase
UP17_14070	ENOG4105VAW	lrga family
UP17_14075	ENOG41067MG	lrgb family
UP17_14080	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
UP17_14085	ENOG4105D64	Mechanosensitive ion channel
UP17_14090	ENOG4107QMU	Mate efflux family protein
UP17_14105	ENOG4105K4I	Scp-like extracellular
UP17_14115	ENOG4105BZU	Histidine kinase
UP17_14120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_14140	ENOG4105CKI	cobalamin synthesis protein
UP17_14145	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
UP17_14150	ENOG4107V49	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
UP17_14155	ENOG4105JAS	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity)
UP17_14160	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
UP17_14170	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
UP17_14180	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
UP17_14185	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
UP17_14190	ENOG4108KGH	TRANSCRIPTIONal
UP17_14200	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
UP17_14215	ENOG4105VSD	UPF0346 protein
UP17_14225	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
UP17_14230	ENOG41060D1	Quinol oxidase
UP17_14235	ENOG4105CCU	oxidase (Subunit III)
UP17_14245	ENOG4105E2S	oxidase) subunit II
UP17_14260	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
UP17_14265	ENOG4108JUB	Transcriptional regulator
UP17_14270	ENOG4108TSC	N-acetyltransferase
UP17_14275	ENOG4107S4Y	M20 DapE family protein YgeY
UP17_14290	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UP17_14310	ENOG4105E0X	reductase
UP17_14315	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
UP17_14330	ENOG41090WU	lipolytic protein G-D-S-L family
UP17_14335	ENOG4108KF3	Electron transport protein SCO1 SenC
UP17_14340	ENOG4108RCR	degv family
UP17_14350	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
UP17_14355	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
UP17_14360	ENOG4105C7B	Threonine dehydratase
UP17_14365	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
UP17_14370	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
UP17_14375	ENOG4106E8G	
UP17_14390	ENOG4107TS3	membrane protein, TerC
UP17_14400	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
UP17_14405	ENOG4107YX5	Pfam:DUF548
UP17_14410	ENOG4108Y6J	UPF0403 protein
UP17_14415	ENOG4105C01	Dihydroxy-acid dehydratase
UP17_14425	ENOG4105C5H	ABC transporter
UP17_14435	ENOG4105EPR	degv family
UP17_14440	ENOG4108V06	Glutathione peroxidase
UP17_14450	ENOG4105CVG	Homoserine O-transsuccinylase
UP17_14465	ENOG4105KST	dependent repressor
UP17_14480	ENOG4105CM2	brancheD-chain amino acid aminotransferase
UP17_14510	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
UP17_14515	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
UP17_14525	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
UP17_14535	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
UP17_14565	ENOG4105E1V	na solute symporter
UP17_14570	ENOG4106CAD	Protein of unknown function (DUF3311)
UP17_14580	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UP17_14600	ENOG4105C26	Dehydrogenase
UP17_14605	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
UP17_14625	ENOG4105CZN	Potassium uptake protein
UP17_14640	ENOG4108MRH	transcriptional regulatory protein
UP17_14665	ENOG41068JE	domain protein
UP17_14665	ENOG41068JE	domain protein
UP17_14720	ENOG4108ZHR	arsR family transcriptional regulator
UP17_14745	ENOG4106KNT	transcriptional regulator
UP17_14750	ENOG4105RD7	BadF BadG BcrA BcrD
UP17_14760	ENOG4105VCP	PTS System
UP17_14775	ENOG4105CK1	PTS System
UP17_14800	ENOG4105C26	Dehydrogenase
UP17_14805	ENOG4105E3J	oxidoreductase
UP17_14845	ENOG4108IQI	permease
UP17_14850	ENOG4106V2I	dimethylaminohydrolase
UP17_14870	ENOG4105CEU	Arginine dihydrolase
UP17_14895	ENOG4105D82	Glutamate dehydrogenase
UP17_14900	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
UP17_14905	ENOG4105F3R	pts system mannose fructose sorbose family iid
UP17_14910	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
UP17_14920	ENOG4106KNT	transcriptional regulator
UP17_14930	ENOG4105CUB	amino acid
UP17_14970	ENOG4105ECB	domain protein
UP17_14995	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
UP17_15025	ENOG41081VK	Ribonuclease
UP17_15045	ENOG4105KHC	sulfurtransferase
UP17_15055	ENOG410890F	Dynamin family
UP17_15065	ENOG41065KQ	synthase
UP17_15070	ENOG4105C2W	permease
UP17_15080	ENOG4105CTD	carboxy-peptidase
UP17_15085	ENOG4105DVT	helicase
UP17_15095	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
UP17_15100	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
UP17_15110	ENOG4107X2U	Inherit from COG: Exonuclease-like protein
UP17_15115	ENOG4108I5C	dEAD DEAH box helicase
UP17_15125	ENOG4105MYT	Heat shock protein
UP17_15165	ENOG4105CSM	endonuclease III
UP17_15175	ENOG4105C5S	asparaginyl-tRNA synthetase
UP17_15180	ENOG4105ERH	Fumarylacetoacetate hydrolase
UP17_15200	ENOG4106P55	Transcriptional regulator
UP17_15230	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
UP17_15240	ENOG4105CHM	Aminotransferase
UP17_15250	ENOG4105DVT	helicase
UP17_15255	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
UP17_15265	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
UP17_15275	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
UP17_15280	ENOG4105CPK	Glycosyl transferase (Group 1
UP17_15285	ENOG4105FJR	Lmbe family
UP17_15290	ENOG4108Z5K	methylglyoxal synthase
UP17_15300	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
UP17_15305	ENOG4108JYZ	YitT family
UP17_15335	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
UP17_15340	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
UP17_15355	ENOG41068YB	TPR repeat-containing protein
UP17_15370	ENOG4105CIH	Imidazole acetol-phosphate transaminase
UP17_15375	ENOG4105KHN	chorismate mutase
UP17_15380	ENOG4105D49	3-dehydroquinate synthase
UP17_15385	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
UP17_15390	ENOG4105BZU	Histidine kinase
UP17_15395	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
UP17_15400	ENOG4105EAH	synthase
UP17_15405	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
UP17_15420	ENOG4105EUJ	GTP cyclohydrolase i
UP17_15425	ENOG4105K70	DNA-binding protein
UP17_15430	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
UP17_15455	ENOG4108JUB	Transcriptional regulator
UP17_15470	ENOG4105CUB	amino acid
UP17_15475	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
UP17_15495	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
UP17_15500	ENOG4105E9Q	Acyl-transferase
UP17_15505	ENOG4105CAT	Cytidine monophosphate kinase
UP17_15515	ENOG4105MSI	germination protein ypeb
UP17_15520	ENOG4105F0V	Cell wall hydrolase
UP17_15530	ENOG4105HDK	L-asparaginase
UP17_15535	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
UP17_15570	ENOG4105I7S	Abortive infection protein
UP17_15575	ENOG4105C9U	ATP-dependent DNA helicase RecQ
UP17_15580	ENOG4105T7X	
UP17_15590	ENOG4108SAX	Membrane
UP17_15600	ENOG4108JQ1	Dehydrogenase
UP17_15615	ENOG4105BZU	Histidine kinase
UP17_15620	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_15625	ENOG4105CRE	cytochrome C
UP17_15630	ENOG4107TWT	Cytochrome c biogenesis protein
UP17_15635	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UP17_15640	ENOG4105FE9	pseudouridine synthase
UP17_15650	ENOG4108JIC	nucleoside recognition domain protein
UP17_15655	ENOG4105DZ1	carboxypeptidase
UP17_15665	ENOG4105D3R	alkyl hydroperoxide reductase
UP17_15670	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
UP17_15685	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
UP17_15690	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
UP17_15705	ENOG4105PTM	secreted protein
UP17_15720	ENOG4105G6R	Stage v sporulation protein ae
UP17_15735	ENOG4105C7N	Xanthine uracil vitamin C permease
UP17_15740	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
UP17_15745	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
UP17_15750	ENOG41082AN	stage II sporulation protein
UP17_15755	ENOG4105DZ1	carboxypeptidase
UP17_15775	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
UP17_15785	ENOG4105I3K	Ferric uptake regulator, Fur family
UP17_15790	ENOG4105MZ9	stage II sporulation protein m
UP17_15810	ENOG4105CPC	Aldo Keto reductase
UP17_15820	ENOG4105K56	Transcriptional regulator
UP17_15835	ENOG4106HZJ	
UP17_15845	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
UP17_15860	ENOG4108IXY	short-chain dehydrogenase reductase
UP17_15865	ENOG41069FQ	Metallo-beta-lactamase superfamily
UP17_15870	ENOG4105II7	pyrroline-5-carboxylate reductase
UP17_15910	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
UP17_15920	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
UP17_15925	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
UP17_15930	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
UP17_15935	ENOG4108HNZ	carboxyl transferase
UP17_15940	ENOG4108ZVT	methylmalonyl-coA epimerase
UP17_15945	ENOG4108VZI	ErfK ybiS ycfS ynhG family protein
UP17_15950	ENOG4108QEG	Membrane
UP17_15955	ENOG4105CDA	abc transporter atp-binding protein
UP17_15960	ENOG4105E5Q	amino acid AbC transporter
UP17_15965	ENOG4108HW3	(ABC) transporter
UP17_15970	ENOG4108Y6J	UPF0403 protein
UP17_15980	ENOG4105D5P	Methylmalonyl-coA mutase
UP17_15985	ENOG4105CMN	Methylmalonyl-coA mutase
UP17_15995	ENOG4105C7S	Dehydrogenase
UP17_16000	ENOG4105CPP	Dehydrogenase, E1 component
UP17_16015	ENOG4107RDP	Dehydrogenase
UP17_16025	ENOG4106CCJ	Protein of unknown function (DUF2627)
UP17_16035	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
UP17_16045	ENOG4107QQR	Sporulation
UP17_16050	ENOG4105S1Z	Stage IV sporulation protein B
UP17_16055	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
UP17_16060	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
UP17_16065	ENOG4105DX0	Hemolysin A
UP17_16070	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
UP17_16080	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
UP17_16085	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
UP17_16095	ENOG4105M7K	Involved in the transcription termination process (By similarity)
UP17_16100	ENOG4108ZSR	alkaline shock protein
UP17_16105	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
UP17_16125	ENOG410644B	Stage III sporulation protein af
UP17_16135	ENOG4105KQ4	Stage iii sporulation protein ad
UP17_16140	ENOG4108CQH	stage III sporulation protein AC
UP17_16145	ENOG4105KR5	Stage iii sporulation protein
UP17_16150	ENOG4105CD2	stage iii sporulation protein aa
UP17_16155	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
UP17_16160	ENOG4105DC7	peptidase M24
UP17_16175	ENOG4105CBJ	Metal-dependent enzyme
UP17_16200	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
UP17_16205	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
UP17_16210	ENOG4105WZW	rhodanese family
UP17_16215	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UP17_16220	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
UP17_16230	ENOG4105C0D	helicase
UP17_16265	ENOG4106855	Competence protein
UP17_16310	ENOG4108NE4	
UP17_16425	ENOG4105C5X	domain protein
UP17_16450	ENOG4105E0M	Sulfatase
UP17_16455	ENOG4105DKQ	ROK family
UP17_16470	ENOG4107ZXI	Rhomboid family
UP17_16480	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
UP17_16505	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
UP17_16510	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
UP17_16515	ENOG4105E2Z	phosphate ABC transporter (Permease
UP17_16520	ENOG4105C8U	phosphate abc transporter
UP17_16525	ENOG4105EXS	phosphate abc transporter
UP17_16530	ENOG4107RF6	penicillin-binding protein
UP17_16545	ENOG4105SXS	Protein of unknown function (DUF456)
UP17_16560	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
UP17_16565	ENOG41063Y9	
UP17_16570	ENOG4108U5J	'-nucleotidase
UP17_16575	ENOG4105N80	Ferric uptake regulator, Fur family
UP17_16580	ENOG4105FAV	ABC, transporter
UP17_16585	ENOG4105FDK	ABC transporter
UP17_16595	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
UP17_16610	ENOG4108IUH	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
UP17_16615	ENOG4105EGD	dinuclear metal center protein, YbgI family
UP17_16635	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
UP17_16640	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
UP17_16645	ENOG4107XJU	UPF0178 protein
UP17_16650	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
UP17_16660	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
UP17_16665	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
UP17_16670	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
UP17_16675	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
UP17_16680	ENOG4105KG3	cytidine deaminase
UP17_16685	ENOG4107YR5	Diacylglycerol kinase
UP17_16690	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
UP17_16695	ENOG4105CTJ	Metal Dependent Phosphohydrolase
UP17_16700	ENOG4105C9A	Phoh family
UP17_16710	ENOG41068P3	sporulation protein YqfC
UP17_16720	ENOG4105DI5	UPF0365 protein
UP17_16725	ENOG4105F7J	membrane-bound serine protease
UP17_16730	ENOG4105KTH	gatB Yqey
UP17_16735	ENOG4105VCC	30S ribosomal protein S21
UP17_16745	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
UP17_16750	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
UP17_16755	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
UP17_16760	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
UP17_16765	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
UP17_16770	ENOG4105CFG	Acts as a chaperone (By similarity)
UP17_16775	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UP17_16780	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
UP17_16785	ENOG4105CSA	Coproporphyrinogen iii oxidase
UP17_16790	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
UP17_16800	ENOG4108ZRV	stage ii sporulation protein p
UP17_16815	ENOG4105TQK	DNA polymerase iii, delta' subunit
UP17_16825	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
UP17_16830	ENOG4108UK2	deaminase
UP17_16835	ENOG4105KQC	Competence protein
UP17_16845	ENOG4105DXX	methyltransferase
UP17_16855	ENOG4108WF2	Metal Dependent Phosphohydrolase
UP17_16860	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
UP17_16865	ENOG410812S	Rna-binding protein
UP17_16875	ENOG4105CQW	ribosome biogenesis GTPase YqeH
UP17_16880	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
UP17_16885	ENOG4105DJ4	phosphatidylserine decarboxylase
UP17_16890	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
UP17_16905	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
UP17_16915	ENOG4105C28	cystathionine
UP17_16930	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
UP17_16945	ENOG4107XRG	penicillin-binding protein
UP17_16950	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
UP17_16970	ENOG4105DBI	uridine monophosphokinase
UP17_16975	ENOG4105CFP	Peptidase U32
UP17_16980	ENOG4105XYU	peptidase (U32 family)
UP17_16985	ENOG4108VQJ	O-methyltransferase
UP17_16995	ENOG4105HHA	aminodeoxychorismate lyase
UP17_17000	ENOG4105VPH	UPF0473 protein
UP17_17005	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
UP17_17010	ENOG4105VBH	UPF0297 protein
UP17_17020	ENOG4105C02	permease
UP17_17025	ENOG41060CR	
UP17_17035	ENOG4105HA9	of methanol dehydrogenase type
UP17_17040	ENOG4108V0P	LemA family
UP17_17045	ENOG4105C7H	Helicase, RecD TraA family
UP17_17055	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
UP17_17060	ENOG4105C3J	Cysteine desulfurase
UP17_17075	ENOG4105D1H	recombination factor protein RarA
UP17_17085	ENOG4106UIA	
UP17_17090	ENOG4105CZV	ABC transporter
UP17_17095	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
UP17_17105	ENOG4108KGH	TRANSCRIPTIONal
UP17_17125	ENOG4105BZ1	(ABC) transporter
UP17_17200	ENOG4107SBE	Glycosyl transferase (Group 1
UP17_17210	ENOG4105CG5	Glycosyl transferase (Group 1
UP17_17215	ENOG4108PQP	glycosyl transferase group 1
UP17_17225	ENOG4105D3Q	Sugar transferase
UP17_17230	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
UP17_17245	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
UP17_17250	ENOG4107YJ4	chain length determinant protein
UP17_17280	ENOG4105CZM	Major Facilitator
UP17_17295	ENOG4108IV0	ABC, transporter
UP17_17300	ENOG4105C0Z	ABC transporter
UP17_17305	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
UP17_17310	ENOG4105C32	Amino acid ABC transporter (Permease)
UP17_17315	ENOG4105CP9	extracellular ligand-binding receptor
UP17_17325	ENOG4105CP9	extracellular ligand-binding receptor
UP17_17330	ENOG4105CUZ	uba thif-type nad fad binding protein
UP17_17345	ENOG4105C9M	aspartyl-trna synthetase
UP17_17350	ENOG4105CUT	histidyl-tRNA synthetase
UP17_17360	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
UP17_17365	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
UP17_17370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
UP17_17375	ENOG4105DQ6	Transposase
UP17_17385	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
UP17_17390	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
UP17_17395	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
UP17_17405	ENOG4105CKP	Polysaccharide Biosynthesis Protein
UP17_17410	ENOG4108QG2	Membrane
UP17_17415	ENOG4105NAP	
UP17_17420	ENOG4105VIE	preprotein translocase, subunit YajC
UP17_17430	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
UP17_17435	ENOG41061AI	Protein of unknown function (DUF2905)
UP17_17445	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
UP17_17475	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
UP17_17480	ENOG4108IYU	L-aspartate oxidase
UP17_17495	ENOG4105CQC	Prephenate dehydratase
UP17_17500	ENOG41090I5	UPF0735 ACT domain-containing protein
UP17_17505	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UP17_17515	ENOG4105K46	50S ribosomal protein l27
UP17_17520	ENOG4105X36	(ribosomal) protein
UP17_17525	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
UP17_17530	ENOG4105C03	ribonuclease
UP17_17550	ENOG41060GV	RNA binding s1 domain protein
UP17_17555	ENOG4107QMS	site-determining protein
UP17_17570	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
UP17_17580	ENOG4105DFF	Rod shape-determining protein mreb
UP17_17585	ENOG4105W5Q	DNA repair protein (RadC
UP17_17600	ENOG4106A3R	peptidase
UP17_17610	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
UP17_17615	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
UP17_17625	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
UP17_17635	ENOG4106AR7	Spore coat protein
UP17_17645	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
UP17_17650	ENOG4105D52	delta-aminolevulinic acid dehydratase
UP17_17660	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
UP17_17670	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
UP17_17680	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
UP17_17685	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
UP17_17690	ENOG4108IUQ	atp-dependent protease
UP17_17695	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
UP17_17700	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
UP17_17710	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
UP17_17715	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
UP17_17725	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
UP17_17730	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
UP17_17735	ENOG4108ZP8	Acetolactate synthase small subunit
UP17_17740	ENOG4105C7K	acetolactate synthase
UP17_17805	ENOG4105M59	Phosphodiesterase, mj0936 family
UP17_17810	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
UP17_17830	ENOG4108XJQ	germination protein
UP17_17840	ENOG41067TZ	transcriptional regulator, MarR family
UP17_17845	ENOG4105PFC	Transcriptional regulator
UP17_17855	ENOG4105E33	succinate dehydrogenase
UP17_17865	ENOG4108NU2	Succinate dehydrogenase cytochrome b558 subunit
UP17_17885	ENOG4105K63	Thioredoxin
UP17_17890	ENOG4105C10	Electron transfer flavoprotein
UP17_17895	ENOG4105BZJ	Electron transfer flavoprotein
UP17_17900	ENOG41060WC	Enoyl-CoA hydratase
UP17_17905	ENOG4107Z3H	Transcriptional regulator, TetR family
UP17_17910	ENOG4105CEY	Amp-dependent synthetase and ligase
UP17_17930	ENOG4105DCG	PHP domain protein
UP17_17940	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
UP17_17945	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
UP17_17950	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
UP17_17955	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
UP17_17960	ENOG4108RWN	rrna methyltransferase
UP17_17965	ENOG41067MF	small acid-soluble spore protein
UP17_17980	ENOG4107KM7	Heat induced stress protein YflT
UP17_17985	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
UP17_17990	ENOG4105CQB	FAD linked oxidase domain protein
UP17_18000	ENOG4105DAA	L-lactate
UP17_18005	ENOG4105JXH	GntR family transcriptional regulator
UP17_18010	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
UP17_18015	ENOG4107QR9	Iron-sulfur cluster binding protein
UP17_18025	ENOG4105CN9	Peptidase m42 family protein
UP17_18045	ENOG410696E	Membrane
UP17_18050	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
UP17_18060	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
UP17_18065	ENOG4105WCN	acetyltransferase
UP17_18070	ENOG4105C22	threonyL-tRNA synthetase
UP17_18090	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
UP17_18095	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
UP17_18105	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
UP17_18110	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
UP17_18120	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
UP17_18125	ENOG4105C2M	dna polymerase I
UP17_18130	ENOG4105EPW	hflc protein
UP17_18140	ENOG4105BZU	Histidine kinase
UP17_18145	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
UP17_18155	ENOG4108HMX	isocitrate dehydrogenase (NADP)
UP17_18160	ENOG4105BZN	citrate synthase
UP17_18165	ENOG4107CWS	Protein of unknown function (DUF441)
UP17_18170	ENOG4108REF	Sporulation integral membrane protein ytvi
UP17_18180	ENOG4107QP3	malate synthase g
UP17_18190	ENOG4105CA9	Pyruvate kinase
UP17_18195	ENOG4105CTQ	phosphohexokinase
UP17_18200	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
UP17_18205	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
UP17_18210	ENOG4107YCY	Transcriptional regulator
UP17_18215	ENOG4105C6K	Malic enzyme
UP17_18220	ENOG4105C0B	DNA polymerase III (alpha subunit)
UP17_18225	ENOG4105VV2	
UP17_18235	ENOG4105SFS	phosphoesterase RecJ domain protein
UP17_18255	ENOG4105E8R	UPF0173 metal-dependent hydrolase
UP17_18260	ENOG4105DC7	peptidase M24
UP17_18270	ENOG4107YZX	Universal stress protein
UP17_18275	ENOG4105CH7	arginosuccinase
UP17_18280	ENOG4105CDH	Citrulline--aspartate ligase
UP17_18290	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
UP17_18300	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
UP17_18310	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
UP17_18315	ENOG4105KBJ	sporulation protein ytfj
UP17_18325	ENOG4105VK3	rdd domain containing protein
UP17_18330	ENOG4105D07	Signal peptide peptidase, SppA
UP17_18335	ENOG4108KKH	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
UP17_18340	ENOG4108RE7	deoxyribonuclease
UP17_18350	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
UP17_18360	ENOG4105D2X	ABC transporter substrate-binding protein
UP17_18375	ENOG4105FR1	rard protein
UP17_18380	ENOG4105EFZ	amidohydrolase
UP17_18385	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
UP17_18395	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
UP17_18405	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
UP17_18410	ENOG4108W76	histidinol phosphate phosphatase hisj family
UP17_18415	ENOG41082JN	Transcriptional regulator
UP17_18425	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
UP17_18430	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
UP17_18445	ENOG4105F1V	Acetoin utilization protein
UP17_18450	ENOG4105W87	Cbs domain
UP17_18455	ENOG4105DGU	Histone deacetylase
UP17_18460	ENOG4105ETE	Transcriptional regulator (LacI family
UP17_18465	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
UP17_18485	ENOG4105C88	aminopeptidase
UP17_18490	ENOG4105DFU	Cell wall formation (By similarity)
UP17_18505	ENOG4108NKM	UPF0354 protein
UP17_18520	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
UP17_18525	ENOG41086D8	Transcriptional regulator
UP17_18530	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
UP17_18545	ENOG4105C8F	Beta-lactamase domain protein
UP17_18550	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
UP17_18560	ENOG4108V15	phosphotransferase enzyme family
UP17_18580	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
UP17_18590	ENOG4107QSE	Dipeptidase
UP17_18595	ENOG4107R73	Mate efflux family protein
UP17_18600	ENOG4107ZTW	SNARE associated Golgi
UP17_18615	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_18625	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_18630	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
UP17_18635	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
UP17_18650	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
UP17_18660	ENOG4107ZXU	DSBA oxidoreductase
UP17_18670	ENOG4105F27	Major Facilitator
UP17_18680	ENOG4105EMU	Dehydrogenase
UP17_18685	ENOG4105ENX	hydrolase
UP17_18690	ENOG4105ST3	Transcriptional regulator
UP17_18700	ENOG4108PJD	permease
UP17_18730	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
UP17_18735	ENOG4105CJZ	response regulator
UP17_18740	ENOG4105EWM	Histidine kinase
UP17_18745	ENOG4105C19	ABC transporter
UP17_18750	ENOG4108HVR	ABC transporter, permease
UP17_18765	ENOG4105YW5	deoR family transcriptional regulator
UP17_18780	ENOG4105CBX	hi0933 family
UP17_18795	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
UP17_18805	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
UP17_18815	ENOG41085GJ	domain protein
UP17_18820	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
UP17_18830	ENOG4105CV8	reductase
UP17_18835	ENOG4105F27	Major Facilitator
UP17_18840	ENOG4105KVH	Transcriptional regulator
UP17_18900	ENOG4108IG5	Transcriptional regulator
UP17_18910	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
UP17_18915	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
UP17_18920	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
UP17_18925	ENOG4105C8Q	Methyl-accepting chemotaxis
UP17_18955	ENOG4105K7W	phage-related replication protein
UP17_18960	ENOG4105K4H	Nlp p60 protein
UP17_18995	ENOG4105KD7	acetyltransferase
UP17_19000	ENOG4105KRN	Transcriptional regulator, abrb family
UP17_19020	ENOG41080TC	multidrug resistance protein
UP17_19025	ENOG4105NX3	Membrane
UP17_19030	ENOG4105VMP	Transcriptional regulator
UP17_19060	ENOG4105E1K	spore germination protein
UP17_19065	ENOG4107T5V	SNARE associated Golgi
UP17_19070	ENOG410841Q	phosphoesterase PA-phosphatase related protein
UP17_19105	ENOG4105D82	Glutamate dehydrogenase
UP17_19110	ENOG4105C8Y	Acetylornithine aminotransferase
UP17_19115	ENOG4105C26	Dehydrogenase
UP17_19120	ENOG4108JUB	Transcriptional regulator
UP17_19125	ENOG4105DQ6	Transposase
UP17_19140	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
UP17_19155	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
UP17_19160	ENOG4105ETD	TRANSCRIPTIONal
UP17_19165	ENOG4105CTS	PTS system mannitol-specific
UP17_19170	ENOG4105D4T	Citrate transporter
UP17_19180	ENOG4108MRH	transcriptional regulatory protein
UP17_19185	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
UP17_19195	ENOG4105D03	DNA-3-methyladenine glycosylase II
UP17_19205	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
UP17_19210	ENOG4107CUJ	Protein of unknown function (DUF2690)
UP17_19220	ENOG41081VB	Hydrolase
UP17_19230	ENOG4106N3A	copper homeostasis protein cutc
UP17_19245	ENOG4107TXC	Transcriptional regulator
UP17_19260	ENOG4105DDN	Pentapeptide repeat-containing protein
UP17_19345	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
UP17_19350	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_19370	ENOG4105WH1	Two component transcriptional regulator luxr family
UP17_19375	ENOG4105ENE	Histidine kinase
UP17_19400	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
UP17_19410	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
UP17_19415	ENOG4106IPI	cyclase, family
UP17_19420	ENOG4105N14	lysine exporter protein LysE YggA
UP17_19430	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
UP17_19435	ENOG4107RZC	phospholipase d
UP17_19450	ENOG4108TVJ	Nitroreductase
UP17_19455	ENOG4107ZXU	DSBA oxidoreductase
UP17_19500	ENOG410870W	N-acetyltransferase
UP17_19505	ENOG4105DQ6	Transposase
UP17_19515	ENOG4105CTX	dehydratase
UP17_19520	ENOG4105C26	Dehydrogenase
UP17_19525	ENOG4105UVJ	5-dehydro-4-deoxyglucarate dehydratase
UP17_19530	ENOG4105DJB	Major Facilitator Superfamily
UP17_19540	ENOG41073TP	transcriptional regulator
UP17_19545	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
UP17_19560	ENOG4107RSM	transcriptional regulator
UP17_19565	ENOG4105ECB	domain protein
UP17_19570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_19575	ENOG41067SE	Tetr family transcriptional regulator
UP17_19580	ENOG4105CN5	Metallo-Beta-Lactamase
UP17_19600	ENOG4105CU9	asparagine synthetase A
UP17_19610	ENOG4105C22	threonyL-tRNA synthetase
UP17_19630	ENOG4108IQI	permease
UP17_19640	ENOG4105CHU	acetyl-coa acetyltransferase
UP17_19655	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UP17_19680	ENOG4108JUB	Transcriptional regulator
UP17_19700	ENOG4105TRI	Hydrolase
UP17_19715	ENOG4108IIH	CoA-transferase subunit B
UP17_19720	ENOG4105D6N	CoA-transferase, subunit a
UP17_19725	ENOG4105CY2	Citrate transporter
UP17_19730	ENOG4108JUB	Transcriptional regulator
UP17_19735	ENOG4105CHU	acetyl-coa acetyltransferase
UP17_19740	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
UP17_19745	ENOG4105DTD	Dehydrogenase
UP17_19760	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
UP17_19780	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
UP17_19785	ENOG4105UNS	Pfam:DUF419
UP17_19815	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_19825	ENOG4108VXD	carboxy-peptidase
UP17_19840	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
UP17_19845	ENOG4105ERH	Fumarylacetoacetate hydrolase
UP17_19900	ENOG4105NAE	bifunctional deaminase-reductase domain protein
UP17_19905	ENOG4105CIS	alcohol dehydrogenase
UP17_19915	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
UP17_19945	ENOG4105CRW	Short chain fatty acid transporter
UP17_19965	ENOG4105KMT	branched-chain amino acid
UP17_19970	ENOG4108UMN	azlc family
UP17_19975	ENOG4107U9B	transcriptional regulator
UP17_19980	ENOG4105VZ8	Transcriptional regulator
UP17_20040	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
UP17_20075	ENOG4106ANW	SMI1_KNR4
UP17_20100	ENOG4106BHF	
UP17_20110	ENOG4108HGU	Histidine kinase
UP17_20120	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
UP17_20155	ENOG4105EEM	helicase
UP17_20175	ENOG4105X3H	Excalibur domain protein
UP17_20185	ENOG4105DY9	regulatoR
UP17_20190	ENOG4108HRK	Histidine kinase
UP17_20245	ENOG4108JQ1	Dehydrogenase
UP17_20250	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
UP17_20255	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
UP17_20285	ENOG4108HWY	Beta-lactamase
UP17_20295	ENOG4105CHH	sulfate transporter
UP17_20300	ENOG4108V2W	Carbonate dehydratase
UP17_20310	ENOG41062D9	Histidine kinase
UP17_20315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_20320	ENOG4107Y9U	Membrane
UP17_20330	ENOG4108Z4K	mutator MutT protein
UP17_20335	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
UP17_20345	ENOG4105TPC	MazG nucleotide pyrophosphohydrolase domain
UP17_20350	ENOG4108URH	decarboxylase
UP17_20390	ENOG4108UMI	ABC transporter, permease
UP17_20395	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
UP17_20420	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
UP17_20435	ENOG4105E1V	na solute symporter
UP17_20440	ENOG4106CAD	Protein of unknown function (DUF3311)
UP17_20460	ENOG4105J7I	hydrolase
UP17_20480	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
UP17_20500	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
UP17_20505	ENOG4105J7D	transcriptional regulator
UP17_20515	ENOG4105EGI	Transcriptional regulator
UP17_20525	ENOG4105C98	muts2 protein
UP17_20530	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
UP17_20545	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
UP17_20570	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UP17_20595	ENOG4105DTE	Xanthine uracil vitamin C permease
UP17_20600	ENOG4105DZC	cytosine deaminase
UP17_20605	ENOG4105DZC	cytosine deaminase
UP17_20610	ENOG4105DZC	cytosine deaminase
UP17_20615	ENOG4105DEF	Extracellular solute-binding protein, family 5
UP17_20630	ENOG4105DEF	Extracellular solute-binding protein, family 5
UP17_20635	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UP17_20645	ENOG4105C3U	ABC transporter
UP17_20650	ENOG4108JQ7	(ABC) transporter
UP17_20655	ENOG4105C2F	Histidine kinase
UP17_20660	ENOG41075H3	AraC family transcriptional regulator
UP17_20670	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
UP17_20680	ENOG4105CNG	UPF0061 protein
UP17_20705	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
UP17_20750	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
UP17_20785	ENOG4105C75	arginyL-tRNA synthetase
UP17_20790	ENOG4108S01	response regulator
UP17_20795	ENOG4105ECK	Fatty Acid Desaturase
UP17_20800	ENOG4105VRS	hydrolase family 18
UP17_20810	ENOG4105VES	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
UP17_20825	ENOG4108TU7	Inherit from COG: (ABC) transporter
UP17_20830	ENOG4105CJ1	ABC, transporter
UP17_20845	ENOG41069ER	domain protein
UP17_20850	ENOG4105WCN	acetyltransferase
UP17_20860	ENOG4105CRN	Aminoglycoside phosphotransferase
UP17_20930	ENOG4105SKE	transcriptional Regulator LysR family
UP17_20945	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_20975	ENOG4105DQ6	Transposase
UP17_21000	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
UP17_21005	ENOG4105CZM	Major Facilitator
UP17_21040	ENOG41067SE	Tetr family transcriptional regulator
UP17_21045	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
UP17_21055	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
UP17_21080	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_21125	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
UP17_21130	ENOG4107X8Z	Acyl-protein synthetase, LuxE
UP17_21135	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
UP17_21140	ENOG4105H3G	oxidoreductase
UP17_21145	ENOG4107RCI	amp-dependent synthetase and ligase
UP17_21165	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_21190	ENOG4108TGR	phosphatase
UP17_21210	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
UP17_21235	ENOG4105ECB	domain protein
UP17_21240	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_21250	ENOG4105VMP	Transcriptional regulator
UP17_21270	ENOG4105D01	(LipO)protein
UP17_21285	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_21300	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
UP17_21310	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
UP17_21365	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_21385	ENOG4105JAB	phenazine biosynthesis protein, phzf family
UP17_21430	ENOG4105EJQ	L-serine dehydratase
UP17_21455	ENOG4105CGH	5'-nucleotidase
UP17_21460	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UP17_21465	ENOG4105T38	integral membrane protein
UP17_21470	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
UP17_21480	ENOG41068WN	
UP17_21490	ENOG4108S3Y	transcriptional regulator
UP17_21505	ENOG4105CJ1	ABC, transporter
UP17_21510	ENOG4105ST3	Transcriptional regulator
UP17_21525	ENOG4105CZN	Potassium uptake protein
UP17_21530	ENOG4107ZYR	domain protein
UP17_21540	ENOG4106SCS	STAS domain
UP17_21545	ENOG41088CC	tellurite resistance protein tehB
UP17_21555	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
UP17_21575	ENOG4105CMR	udp-glucose 4-epimerase
UP17_21580	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
UP17_21590	ENOG4108RYK	Nad-dependent epimerase dehydratase
UP17_21600	ENOG4108R9S	DSBA oxidoreductase
UP17_21605	ENOG4108Z40	Transcriptional regulator
UP17_21630	ENOG41082BM	Transcriptional regulator, arsr family
UP17_21635	ENOG4105ECB	domain protein
UP17_21640	ENOG41062ES	Transcriptional regulator
UP17_21645	ENOG4105SZ6	Thioredoxin
UP17_21665	ENOG4107ZBN	O-methyltransferase
UP17_21690	ENOG4105HRU	Glyoxalase Bleomycin resistance protein (Dioxygenase
UP17_21695	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
UP17_21700	ENOG4105CZM	Major Facilitator
UP17_21715	ENOG4105CZV	ABC transporter
UP17_21735	ENOG4105RHY	Pfam:UPF0157
UP17_21745	ENOG4105WH1	Two component transcriptional regulator luxr family
UP17_21755	ENOG4107T5V	SNARE associated Golgi
UP17_21770	ENOG4108ZJ4	polysaccharide deacetylase
UP17_21775	ENOG41062D9	Histidine kinase
UP17_21780	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_21795	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
UP17_21800	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
UP17_21820	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
UP17_21825	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
UP17_21840	ENOG4105DUX	Transporter
UP17_21850	ENOG4108P49	AntiSigma factor
UP17_21855	ENOG4105JVQ	RNA Polymerase
UP17_21860	ENOG4108ZJ4	polysaccharide deacetylase
UP17_21880	ENOG4105CPD	ethanolamine ammonia-lyase
UP17_21885	ENOG4105DYY	Reactivating factor for ethanolamine ammonia lyase
UP17_21890	ENOG4105ENY	Ethanolamine utilization protein eutH
UP17_21915	ENOG4107T89	von Willebrand factor, type A
UP17_21920	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
UP17_21930	ENOG4108UW5	maltose o-acetyltransferase
UP17_21940	ENOG4105X5K	response regulator receiver protein
UP17_21960	ENOG4105BZ8	glutamate synthase
UP17_21965	ENOG4105CBC	glutamate synthase
UP17_21970	ENOG4105C5Q	Transcriptional regulator
UP17_21990	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
UP17_21995	ENOG4105C8T	Leucyl-tRNA synthetase
UP17_22010	ENOG4105N5T	Radical SAM Protein
UP17_22025	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
UP17_22030	ENOG4108Z0R	Transferase
UP17_22035	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
UP17_22060	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
UP17_22090	ENOG4105EWC	Purine nucleoside phosphorylase
UP17_22105	ENOG4105D2X	ABC transporter substrate-binding protein
UP17_22115	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
UP17_22120	ENOG41062IR	nudix hydrolase
UP17_22135	ENOG4108RMU	ferritin dps family protein
UP17_22140	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
UP17_22145	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
UP17_22155	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
UP17_22160	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
UP17_22165	ENOG4108MRH	transcriptional regulatory protein
UP17_22170	ENOG4105DTQ	mandelate racemase muconate lactonizing
UP17_22175	ENOG4105CEY	Amp-dependent synthetase and ligase
UP17_22180	ENOG4108IPT	Naphthoate synthase
UP17_22190	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
UP17_22195	ENOG4105E4F	Isochorismate synthase
UP17_22200	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
UP17_22340	ENOG4105KT7	mgtC SapB transporter
UP17_22355	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UP17_22385	ENOG4105C26	Dehydrogenase
UP17_22390	ENOG4105CK7	Sodium proline symporter
UP17_22395	ENOG4107YHD	transcriptional regulator
UP17_22400	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
UP17_22410	ENOG4105EFA	4-hydroxyphenylacetate
UP17_22420	ENOG4108W8B	Beta-lactamase domain protein
UP17_22425	ENOG4105BZG	amino acid carrier protein
UP17_22430	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
UP17_22445	ENOG4108ZIA	glycerol-3-phosphate responsive antiterminator
UP17_22460	ENOG4105WAB	arsR family transcriptional regulator
UP17_22465	ENOG4108RWP	Major Facilitator Superfamily protein
UP17_22475	ENOG4108IQI	permease
UP17_22505	ENOG4108NGU	Transcriptional regulator
UP17_22520	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_22525	ENOG4107ZE5	PPIases accelerate the folding of proteins
UP17_22545	ENOG41085AS	UPF0473 protein
UP17_22550	ENOG4105EMN	RNA polymerase sigma factor
UP17_22565	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
UP17_22575	ENOG4105WDJ	50S ribosomal protein L33
UP17_22580	ENOG4105CKI	cobalamin synthesis protein
UP17_22585	ENOG4105PKS	Excinuclease abc c subunit domain protein
UP17_22595	ENOG4105G6Z	alkaline phosphatase
UP17_22605	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_22610	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
UP17_22630	ENOG41086DT	Membrane protein of unknown function
UP17_22635	ENOG4105WAB	arsR family transcriptional regulator
UP17_22640	ENOG4105F27	Major Facilitator
UP17_22650	ENOG4105C85	amino acid
UP17_22680	ENOG4105E1K	spore germination protein
UP17_22700	ENOG4106DF4	Sigma-70, region 4
UP17_22735	ENOG4105D94	Major Facilitator Superfamily
UP17_22740	ENOG4107R7I	amino acid
UP17_22745	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
UP17_22750	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
UP17_22760	ENOG4105VRS	hydrolase family 18
UP17_22765	ENOG4107PBV	potassium channel
UP17_22780	ENOG4107QW4	alcohol dehydrogenase
UP17_22785	ENOG4105WG9	Conserved Protein
UP17_22795	ENOG4105C8J	)-transporter
UP17_22805	ENOG4105CHM	Aminotransferase
UP17_22810	ENOG4108ZB6	transcriptional regulator AsnC family
UP17_22815	ENOG4108MUZ	hydrolase
UP17_22825	ENOG4105C87	Aminotransferase class I and II
UP17_22840	ENOG4108QCI	YvbH-like oligomerisation region
UP17_22845	ENOG4108YM7	Gcn5-related n-acetyltransferase
UP17_22855	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
UP17_22860	ENOG4105Y38	Kinase-associated protein B
UP17_22880	ENOG4105D65	subunit l
UP17_22885	ENOG4105HC0	Na H antiporter
UP17_22890	ENOG4108ZE9	Monovalent cation H antiporter subunit C
UP17_22895	ENOG4108JPZ	Monovalent cation H antiporter subunit D
UP17_22900	ENOG4105SC1	monovalent cation H antiporter subunit E
UP17_22910	ENOG4105KJM	monovalent cation h antiporter subunit g
UP17_22920	ENOG4105KA0	thioesterase Superfamily protein
UP17_22925	ENOG4108UX3	'-nucleotidase
UP17_22935	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
UP17_22940	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
UP17_22950	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
UP17_22965	ENOG41069ER	domain protein
UP17_22970	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_22985	ENOG4105CEP	NADH dehydrogenase
UP17_22990	ENOG4105CAY	ferredoxin--nadp reductase
UP17_22995	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
UP17_23005	ENOG4105ZKE	UPF0349 protein
UP17_23020	ENOG41083MR	nifu domain-containing protein
UP17_23025	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
UP17_23030	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
UP17_23035	ENOG4105D6E	homoserine dehydrogenase
UP17_23050	ENOG4108W5N	phosphatidylglycerophosphatase a
UP17_23055	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
UP17_23075	ENOG4105MMD	transcriptional regulator
UP17_23080	ENOG4106EGE	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
UP17_23085	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
UP17_23090	ENOG4105FAA	peptidase M23
UP17_23095	ENOG4108YTE	sporulation protein YunB
UP17_23100	ENOG4108ESY	Metal dependent phosphohydrolase
UP17_23105	ENOG4105KZD	Domain of unknown function (DUF1805)
UP17_23110	ENOG4107R8B	5'-nucleotidase
UP17_23120	ENOG4105I3N	Conserved Protein
UP17_23125	ENOG4105DIW	FeS assembly protein SUFB
UP17_23130	ENOG4108UNV	SUF system FeS assembly protein, NifU family
UP17_23140	ENOG4105JRK	feS assembly protein SufD
UP17_23145	ENOG4105C3K	feS assembly ATPase SufC
UP17_23150	ENOG4105D01	(LipO)protein
UP17_23155	ENOG4108UMI	ABC transporter, permease
UP17_23160	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
UP17_23180	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
UP17_23185	ENOG41080E8	Transcriptional regulator, Spx MgsR family
UP17_23190	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_23195	ENOG4105CHU	acetyl-coa acetyltransferase
UP17_23230	ENOG4108IQI	permease
UP17_23235	ENOG4105CG3	alpha amylase, catalytic region
UP17_23270	ENOG4105JSC	dimethylmenaquinone methyltransferase
UP17_23285	ENOG4108IPW	abc transporter atp-binding protein
UP17_23290	ENOG4105CM4	permease protein
UP17_23295	ENOG4105DHS	permease protein
UP17_23310	ENOG4105EWU	Squalene--hopene cyclase
UP17_23325	ENOG41062D9	Histidine kinase
UP17_23330	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_23335	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
UP17_23340	ENOG4108S01	response regulator
UP17_23345	ENOG4108ZGX	Histidine kinase
UP17_23350	ENOG4105ECK	Fatty Acid Desaturase
UP17_23355	ENOG4108MRH	transcriptional regulatory protein
UP17_23360	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
UP17_23375	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
UP17_23385	ENOG4108KAM	Transcriptional regulator
UP17_23390	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
UP17_23395	ENOG4108ZSU	Uncharacterized conserved protein (DUF2294)
UP17_23400	ENOG4108JB9	formate dehydrogenase
UP17_23425	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
UP17_23430	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
UP17_23440	ENOG4105XZU	Preprotein translocase, subunit SecG
UP17_23450	ENOG4108VXD	carboxy-peptidase
UP17_23460	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
UP17_23465	ENOG4105CP7	Triose-phosphate isomerase
UP17_23470	ENOG4105BZA	Phosphoglycerate kinase
UP17_23475	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
UP17_23490	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
UP17_23500	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
UP17_23505	ENOG4105KRI	phosphocarrier protein (HPr
UP17_23515	ENOG4105CHW	UPF0052 protein
UP17_23520	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
UP17_23525	ENOG4108Z4K	mutator MutT protein
UP17_23530	ENOG4105C3M	thioredoxin reductase
UP17_23540	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
UP17_23545	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
UP17_23550	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
UP17_23555	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
UP17_23560	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
UP17_23565	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
UP17_23570	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
UP17_23575	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
UP17_23590	ENOG4108S4C	acetyltransferase
UP17_23595	ENOG4107XGZ	Hydrolase
UP17_23600	ENOG4105HKU	nucleoside recognition domain-containing protein
UP17_23605	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
UP17_23610	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
UP17_23615	ENOG4108PY7	
UP17_23620	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
UP17_23625	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
UP17_23635	ENOG4105CH6	catalase
UP17_23640	ENOG4105EYF	MMPL domain protein
UP17_23645	ENOG4108YYC	ycei family
UP17_23650	ENOG4108IHU	transport system permease protein
UP17_23655	ENOG4105DQ5	transport system permease protein
UP17_23660	ENOG4108MES	Periplasmic binding protein
UP17_23670	ENOG4105CN1	protease
UP17_23680	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
UP17_23685	ENOG4105CAK	Cell division ATP-binding protein ftsE
UP17_23700	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
UP17_23705	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
UP17_23710	ENOG4108IMY	Transcriptional regulator
UP17_23715	ENOG4105MS2	ribosomal subunit Interface protein
UP17_23720	ENOG41069ZS	flagellar protein
UP17_23725	ENOG4105MQ3	flagellar protein FliS
UP17_23730	ENOG4107RT6	flagellar hook-associated
UP17_23735	ENOG41083S7	flagellar protein FlaG
UP17_23745	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
UP17_23750	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
UP17_23760	ENOG4105DTJ	flagellar hook-associated protein
UP17_23765	ENOG4105E1Q	flagellar hook-associated protein
UP17_23780	ENOG4105RU3	
UP17_23800	ENOG4105WH1	Two component transcriptional regulator luxr family
UP17_23805	ENOG4105BZU	Histidine kinase
UP17_23810	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
UP17_23815	ENOG4108KGH	TRANSCRIPTIONal
UP17_23820	ENOG4105ESV	Glycosyl transferase, family 4
UP17_23840	ENOG4105CJR	Integral membrane protein (MviN
UP17_23845	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
UP17_23850	ENOG4105EY8	ABC transporter
UP17_23875	ENOG4107ZIC	Glycerol-3-phosphate cytidylyltransferase
UP17_23880	ENOG4107RZX	Teichoic acid biosynthesis protein
UP17_23885	ENOG4105K4H	Nlp p60 protein
UP17_23895	ENOG4105E0M	Sulfatase
UP17_23910	ENOG4106KBF	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane (By similarity)
UP17_23930	ENOG4107RVG	penicillin-binding protein
UP17_23950	ENOG4105KBK	Zinc finger, swim domain protein
UP17_23955	ENOG4105C0D	helicase
UP17_23960	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
UP17_23965	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
UP17_23980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UP17_23985	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
UP17_23990	ENOG4105DEF	Extracellular solute-binding protein, family 5
UP17_23995	ENOG4108JQ7	(ABC) transporter
UP17_24000	ENOG4105C3U	ABC transporter
UP17_24010	ENOG4108UUM	single-stranded DNA-binding protein
UP17_24035	ENOG4105CGA	flagellar basal-body rod protein FlgG
UP17_24045	ENOG4105DFF	Rod shape-determining protein mreb
UP17_24050	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
UP17_24055	ENOG4105FRN	stage II sporulation protein
UP17_24080	ENOG4106778	Protein of unknown function (DUF1146)
UP17_24085	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
UP17_24090	ENOG4105C8S	subunit m
UP17_24095	ENOG4105D65	subunit l
UP17_24100	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
UP17_24110	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
UP17_24120	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
UP17_24125	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
UP17_24130	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
UP17_24135	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
UP17_24140	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
UP17_24145	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
UP17_24150	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
UP17_24155	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
UP17_24160	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
UP17_24170	ENOG4105WS6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
UP17_24175	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
UP17_24185	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
UP17_24190	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
UP17_24195	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
UP17_24205	ENOG4108UIC	UPF0340 protein
UP17_24210	ENOG4108YZG	isomerase
UP17_24225	ENOG410815N	Probably functions as a manganese efflux pump (By similarity)
UP17_24230	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
UP17_24235	ENOG4108ZXQ	stage ii sporulation protein r
UP17_24240	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
UP17_24245	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
UP17_24255	ENOG4107104	thymidine kinase
UP17_24260	ENOG4105VFB	Binds the 23S rRNA (By similarity)
UP17_24265	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
UP17_24270	ENOG4105CBT	Fructose-1,6-bisphosphatase
UP17_24275	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
UP17_24280	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
UP17_24290	ENOG410812K	response regulator receiver protein
UP17_24300	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
UP17_24310	ENOG4105D5P	Methylmalonyl-coA mutase
UP17_24320	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_24325	ENOG4105C1G	acyl-Coa dehydrogenase
UP17_24330	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
UP17_24340	ENOG4105DF6	Fe-S oxidoreductase
UP17_24355	ENOG4105C75	arginyL-tRNA synthetase
UP17_24365	ENOG4105CYW	agmatinase
UP17_24370	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
UP17_24375	ENOG4105BZ4	penicillin-binding protein
UP17_24380	ENOG4108XFG	YwhD family
UP17_24385	ENOG4108Z4T	Peptidase M50
UP17_24390	ENOG41069HH	4-oxalocrotonate tautomerase
UP17_24400	ENOG4105DCI	Phosphohydrolase
UP17_24410	ENOG4108VCI	transcription factor, rsfa family
UP17_24415	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
UP17_24420	ENOG4108IJ2	phosphate acetyltransferase
UP17_24425	ENOG4107JTW	chlorite dismutase
UP17_24445	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
UP17_24460	ENOG4105D06	uba thif-type nad fad binding protein
UP17_24465	ENOG41067WU	Molybdopterin converting factor (Subunit 1)
UP17_24470	ENOG4108ZAF	Molybdopterin
UP17_24475	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
UP17_24480	ENOG4105DWF	phosphomethylpyrimidine kinase
UP17_24490	ENOG4108TN2	lmbE family
UP17_24495	ENOG4105CZM	Major Facilitator
UP17_24500	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
UP17_24505	ENOG4105D8V	Glucose sorbosone dehydrogenase
UP17_24510	ENOG4105J7I	hydrolase
UP17_24520	ENOG4108Z66	YbaK ebsC protein
UP17_24525	ENOG4105CMG	Carbohydrate kinase
UP17_24545	ENOG4108WBT	adenosyltransferase
UP17_24555	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
UP17_24560	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
UP17_24570	ENOG4107QZB	decarboxylase
UP17_24575	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
UP17_24580	ENOG4105E0A	ABC, transporter
UP17_24585	ENOG4105EHG	Permease protein
UP17_24590	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
UP17_24605	ENOG4108M1A	Chitin-binding protein
UP17_24620	ENOG4105C9U	ATP-dependent DNA helicase RecQ
UP17_24625	ENOG4105C5H	ABC transporter
UP17_24640	ENOG4105C1J	atp-dependent rna helicase
UP17_24645	ENOG4105C7N	Xanthine uracil vitamin C permease
UP17_24685	ENOG4105CIY	formyltetrahydrofolate deformylase
UP17_24690	ENOG4105EAB	amino acid AbC transporter
UP17_24695	ENOG4105E5Q	amino acid AbC transporter
UP17_24705	ENOG4105CX6	glutaminyL-tRNA synthetase
UP17_24710	ENOG4105E0X	reductase
UP17_24715	ENOG4105D9N	nucleoside
UP17_24720	ENOG4105GR3	Histidine kinase
UP17_24725	ENOG4108STX	response regulator
UP17_24760	ENOG4107YUH	hydrolase
UP17_24765	ENOG4105CK2	sodium dicarboxylate symporter
UP17_24775	ENOG4105DR4	Methyltransferase
UP17_24785	ENOG4105C5Q	Transcriptional regulator
UP17_24790	ENOG4105D82	Glutamate dehydrogenase
UP17_24800	ENOG4108RVA	ribokinase
UP17_24830	ENOG4105DY8	decarboxylase
UP17_24845	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
UP17_24850	ENOG4105CH6	catalase
UP17_24855	ENOG4105C1J	atp-dependent rna helicase
UP17_24860	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
UP17_24865	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
UP17_24870	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
UP17_24875	ENOG4105C0H	protease
UP17_24880	ENOG4105Q2H	domain protein
UP17_24895	ENOG4105BZU	Histidine kinase
UP17_24900	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
UP17_24905	ENOG4105E4C	Lytic transglycosylase catalytic
UP17_24930	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
UP17_24935	ENOG4105CDU	Replicative dna helicase
UP17_24940	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
UP17_24945	ENOG4105BZR	domain protein
UP17_24955	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_24960	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
UP17_24965	ENOG4108UUM	single-stranded DNA-binding protein
UP17_24970	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
UP17_24975	ENOG4105C3G	gtp-binding protein
UP17_24980	ENOG4105VDK	protein, conserved in bacteria
UP17_24985	ENOG4105D8X	mechanosensitive ion channel
UP17_24990	ENOG4108ZDA	Sporulation protein YyaC
UP17_25000	ENOG4105FA0	parb-like partition protein
UP17_25005	ENOG4107QJE	Chromosome Partitioning Protein
UP17_25010	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
UP17_25015	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
UP17_25020	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
UP17_25025	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
UP17_25030	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_25040	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
UP17_25045	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
UP17_25050	ENOG4105VG0	50S ribosomal protein l34
UP17_25075	ENOG4105BZU	Histidine kinase
UP17_25095	ENOG4107Z3H	Transcriptional regulator, TetR family
UP17_25135	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_25150	ENOG4105C2J	ABC transporter
UP17_25160	ENOG4105DQ6	Transposase
UP17_25210	ENOG4105KD7	acetyltransferase
UP17_25235	ENOG4108Z5V	transcriptional regulator, merr family
UP17_25240	ENOG4108UQV	Membrane
UP17_25260	ENOG41086D8	Transcriptional regulator
UP17_25280	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
UP17_25290	ENOG4107Y9E	nuclease
UP17_25325	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
UP17_25430	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
UP17_25435	ENOG41086VY	Fic/DOC family
UP17_25455	ENOG4108JU3	Alkyl hydroperoxide reductase
UP17_25460	ENOG4105D3R	alkyl hydroperoxide reductase
UP17_25465	ENOG4108IQI	permease
UP17_25475	ENOG4105CXN	decarboxylase
UP17_25480	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
UP17_25485	ENOG4105KVH	Transcriptional regulator
UP17_25490	ENOG4108UW5	maltose o-acetyltransferase
UP17_25535	ENOG4107R73	Mate efflux family protein
UP17_25540	ENOG4108JQ7	(ABC) transporter
UP17_25550	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
UP17_25555	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
UP17_25560	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
UP17_25585	ENOG4105EKQ	RNA-directed DNA polymerase
UP17_25595	ENOG4105EMN	RNA polymerase sigma factor
UP17_25670	ENOG4105K4H	Nlp p60 protein
UP17_25785	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
UP17_25835	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
UP17_25845	ENOG4105YWU	small acid-soluble spore protein