locus-tag	class	description
B1NLA3E_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B1NLA3E_00010	COG0592	DNA-directed DNA polymerase activity
B1NLA3E_00015	COG2501	S4 domain
B1NLA3E_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1NLA3E_00030	COG0187	DNA topoisomerase II activity
B1NLA3E_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1NLA3E_00045	COG0516	GMP reductase activity
B1NLA3E_00045	COG0517	IMP dehydrogenase activity
B1NLA3E_00060	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B1NLA3E_00065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1NLA3E_00070	COG1428	Deoxynucleoside kinase
B1NLA3E_00075	COG1428	Deoxynucleoside kinase
B1NLA3E_00080	COG1388	LysM domain
B1NLA3E_00080	COG3858	chitin binding
B1NLA3E_00085	COG2200	EAL domain
B1NLA3E_00085	COG2199	diguanylate cyclase activity
B1NLA3E_00090	COG0590	tRNA wobble adenosine to inosine editing
B1NLA3E_00095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B1NLA3E_00100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B1NLA3E_00105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B1NLA3E_00125	COG1982	Orn Lys Arg decarboxylase major
B1NLA3E_00130	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B1NLA3E_00135	COG3870	Protein conserved in bacteria
B1NLA3E_00140	COG0470	DNA polymerase III
B1NLA3E_00145	COG1774	PSP1 C-terminal conserved region
B1NLA3E_00150	COG4467	Involved in initiation control of chromosome replication
B1NLA3E_00155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B1NLA3E_00165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B1NLA3E_00170	COG2002	toxin-antitoxin pair type II binding
B1NLA3E_00180	COG0084	hydrolase, TatD family'
B1NLA3E_00185	COG3583	domain protein
B1NLA3E_00185	COG3584	3D domain protein
B1NLA3E_00195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B1NLA3E_00205	COG4466	Protein conserved in bacteria
B1NLA3E_00215	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B1NLA3E_00220	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1NLA3E_00225	COG0251	oxidation-reduction process
B1NLA3E_00230	COG2088	sporulation resulting in formation of a cellular spore
B1NLA3E_00235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1NLA3E_00240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B1NLA3E_00245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B1NLA3E_00250	COG0193	aminoacyl-tRNA hydrolase activity
B1NLA3E_00260	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B1NLA3E_00265	COG2002	toxin-antitoxin pair type II binding
B1NLA3E_00270	COG2244	polysaccharide biosynthetic process
B1NLA3E_00275	COG3956	TIGRFAM MazG family protein
B1NLA3E_00280	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B1NLA3E_00300	COG1098	S1 RNA binding domain
B1NLA3E_00305	COG2208	phosphoserine phosphatase activity
B1NLA3E_00310	COG2304	oxidoreductase activity
B1NLA3E_00315	COG0515	serine threonine protein kinase
B1NLA3E_00325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1NLA3E_00330	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B1NLA3E_00335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B1NLA3E_00340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1NLA3E_00345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_00350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B1NLA3E_00355	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B1NLA3E_00360	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B1NLA3E_00365	COG1396	sequence-specific DNA binding
B1NLA3E_00370	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B1NLA3E_00385	COG3880	PFAM UvrB UvrC protein
B1NLA3E_00390	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B1NLA3E_00395	COG0542	response to heat
B1NLA3E_00400	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B1NLA3E_00405	COG4956	integral membrane protein (PIN domain superfamily)
B1NLA3E_00410	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B1NLA3E_00415	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B1NLA3E_00420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1NLA3E_00425	COG1045	serine acetyltransferase
B1NLA3E_00430	COG0215	cysteine-tRNA ligase activity
B1NLA3E_00440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1NLA3E_00445	COG3688	RNA-binding protein containing a PIN domain
B1NLA3E_00455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1NLA3E_00460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1NLA3E_00465	COG0250	Participates in transcription elongation, termination and antitermination
B1NLA3E_00475	COG0081	regulation of translation
B1NLA3E_00490	COG2813	Specifically methylates the guanine in position
B1NLA3E_00495	COG0085	RNA polymerase activity
B1NLA3E_00500	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B1NLA3E_00505	COG1358	cellular component organization or biogenesis
B1NLA3E_00510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B1NLA3E_00515	COG0049	tRNA binding
B1NLA3E_00525	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1NLA3E_00535	COG0051	transcription antitermination factor activity, RNA binding
B1NLA3E_00540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B1NLA3E_00545	COG0088	Forms part of the polypeptide exit tunnel
B1NLA3E_00560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B1NLA3E_00565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B1NLA3E_00570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B1NLA3E_00575	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B1NLA3E_00580	COG0255	Belongs to the universal ribosomal protein uL29 family
B1NLA3E_00590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B1NLA3E_00595	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B1NLA3E_00615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B1NLA3E_00620	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B1NLA3E_00625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B1NLA3E_00630	COG1841	ribosomal large subunit assembly
B1NLA3E_00635	COG0200	Binds to the 23S rRNA
B1NLA3E_00640	COG0201	protein transport
B1NLA3E_00645	COG0563	adenylate kinase activity
B1NLA3E_00650	COG0024	Methionine aminopeptidase
B1NLA3E_00655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B1NLA3E_00660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B1NLA3E_00665	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B1NLA3E_00670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B1NLA3E_00675	COG0202	RNA polymerase activity
B1NLA3E_00680	COG0203	ribosomal protein L17
B1NLA3E_00685	COG1122	ATPase activity
B1NLA3E_00690	COG1122	ATPase activity
B1NLA3E_00695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B1NLA3E_00705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B1NLA3E_00710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B1NLA3E_00740	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_00745	COG0489	protein tyrosine kinase activity
B1NLA3E_00755	COG2194	sulfuric ester hydrolase activity
B1NLA3E_00760	COG0726	polysaccharide deacetylase
B1NLA3E_00775	COG1595	DNA-templated transcription, initiation
B1NLA3E_00780	COG5662	AntiSigma factor
B1NLA3E_00785	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B1NLA3E_00790	COG4856	YbbR-like protein
B1NLA3E_00795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1NLA3E_00800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1NLA3E_00805	COG0778	Nitroreductase
B1NLA3E_00815	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_00830	COG3711	transcriptional antiterminator
B1NLA3E_00850	COG2323	membrane
B1NLA3E_00855	COG3300	MHYT domain
B1NLA3E_00855	COG5001	Diguanylate cyclase
B1NLA3E_00870	COG1253	flavin adenine dinucleotide binding
B1NLA3E_00875	COG2239	Acts as a magnesium transporter
B1NLA3E_00885	COG1181	Belongs to the D-alanine--D-alanine ligase family
B1NLA3E_00890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B1NLA3E_00900	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_00905	COG4294	response to UV
B1NLA3E_00910	COG3402	PFAM membrane-flanked domain
B1NLA3E_00915	COG3428	Bacterial PH domain
B1NLA3E_00920	COG0705	Rhomboid family
B1NLA3E_00925	COG0736	holo-[acyl-carrier-protein] synthase activity
B1NLA3E_00930	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B1NLA3E_00940	COG0864	Transcriptional regulator
B1NLA3E_00945	COG2337	Toxic component of a toxin-antitoxin (TA) module
B1NLA3E_00950	COG2183	response to ionizing radiation
B1NLA3E_00955	COG3091	SprT-like family
B1NLA3E_00960	COG0802	atpase or kinase
B1NLA3E_00965	COG1214	PFAM Peptidase M22, glycoprotease
B1NLA3E_00970	COG0456	acetyltransferase
B1NLA3E_00980	COG0488	(ABC) transporter
B1NLA3E_00985	COG0315	cyclic pyranopterin monophosphate synthase activity
B1NLA3E_00990	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B1NLA3E_00995	COG2508	Transcriptional regulator
B1NLA3E_01000	COG1053	succinate dehydrogenase
B1NLA3E_01010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_01015	COG0805	protein transport
B1NLA3E_01025	COG1266	CAAX protease self-immunity
B1NLA3E_01030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B1NLA3E_01040	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_01045	COG2856	Zn peptidase
B1NLA3E_01070	COG1396	sequence-specific DNA binding
B1NLA3E_01075	COG1476	TRANSCRIPTIONal
B1NLA3E_01150	COG2201	protein-glutamate methylesterase activity
B1NLA3E_01170	COG1595	DNA-templated transcription, initiation
B1NLA3E_01185	COG5484	DNA packaging
B1NLA3E_01190	COG1783	phage Terminase large subunit
B1NLA3E_01195	COG5518	Phage portal protein
B1NLA3E_01200	COG2369	cell adhesion
B1NLA3E_01210	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B1NLA3E_01215	COG4653	Phage capsid family
B1NLA3E_01330	COG1196	nuclear chromosome segregation
B1NLA3E_01330	COG0741	lytic transglycosylase activity
B1NLA3E_01330	COG0739	heme binding
B1NLA3E_01380	COG3959	Transketolase, thiamine diphosphate binding domain
B1NLA3E_01385	COG3958	Transketolase
B1NLA3E_01390	COG1063	alcohol dehydrogenase
B1NLA3E_01400	COG2186	Transcriptional regulator
B1NLA3E_01405	COG0205	6-phosphofructokinase activity
B1NLA3E_01420	COG0277	FAD linked oxidase domain protein
B1NLA3E_01425	COG2086	electron transfer activity
B1NLA3E_01430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_01440	COG2086	electron transfer activity
B1NLA3E_01445	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_01450	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B1NLA3E_01455	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_01460	COG2223	nitrite transmembrane transporter activity
B1NLA3E_01465	COG1070	Carbohydrate kinase
B1NLA3E_01470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B1NLA3E_01475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1NLA3E_01485	COG0039	L-malate dehydrogenase activity
B1NLA3E_01490	COG2267	carboxylic ester hydrolase activity
B1NLA3E_01495	COG2350	Protein conserved in bacteria
B1NLA3E_01500	COG0714	Associated with various cellular activities
B1NLA3E_01505	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B1NLA3E_01510	COG1305	Transglutaminase-like
B1NLA3E_01515	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1NLA3E_01515	COG0519	Catalyzes the synthesis of GMP from XMP
B1NLA3E_01520	COG2252	PERMEase
B1NLA3E_01525	COG3711	transcriptional antiterminator
B1NLA3E_01530	COG1263	PTS System
B1NLA3E_01530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1NLA3E_01530	COG2190	(PTS) system
B1NLA3E_01540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B1NLA3E_01545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B1NLA3E_01550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1NLA3E_01555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B1NLA3E_01560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B1NLA3E_01575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B1NLA3E_01580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B1NLA3E_01585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B1NLA3E_01595	COG0151	Belongs to the GarS family
B1NLA3E_01610	COG1470	cell adhesion involved in biofilm formation
B1NLA3E_01615	COG4496	protein, YerC YecD
B1NLA3E_01620	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B1NLA3E_01625	COG0210	DNA helicase
B1NLA3E_01630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1NLA3E_01635	COG4851	CamS sex pheromone cAM373 precursor
B1NLA3E_01640	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_01645	COG2224	Isocitrate lyase
B1NLA3E_01655	COG5506	Protein of unknown function (DUF1694)
B1NLA3E_01660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1NLA3E_01665	COG0154	amidase activity
B1NLA3E_01670	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1NLA3E_01675	COG2205	protein histidine kinase activity
B1NLA3E_01680	COG1597	lipid kinase activity
B1NLA3E_01685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B1NLA3E_01695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1NLA3E_01700	COG0166	Belongs to the GPI family
B1NLA3E_01705	COG1733	regulation of RNA biosynthetic process
B1NLA3E_01715	COG0730	response to heat
B1NLA3E_01725	COG1309	transcriptional regulator
B1NLA3E_01730	COG1272	protein, Hemolysin III
B1NLA3E_01740	COG2897	thiosulfate sulfurtransferase activity
B1NLA3E_01750	COG1607	acyl-coa hydrolase
B1NLA3E_01755	COG1607	acyl-coa hydrolase
B1NLA3E_01760	COG0789	Transcriptional regulator
B1NLA3E_01765	COG1664	Polymer-forming cytoskeletal
B1NLA3E_01775	COG2409	Drug exporters of the RND superfamily
B1NLA3E_01780	COG3279	Response regulator of the LytR AlgR family
B1NLA3E_01785	COG0427	acetyl-CoA hydrolase
B1NLA3E_01840	COG0596	Alpha beta hydrolase
B1NLA3E_01855	COG0697	spore germination
B1NLA3E_01860	COG2116	formate transmembrane transporter activity
B1NLA3E_01875	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_01940	COG1492	cobalamin metabolic process
B1NLA3E_01955	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B1NLA3E_01960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1NLA3E_01970	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B1NLA3E_02020	COG1404	Belongs to the peptidase S8 family
B1NLA3E_02025	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_02040	COG0789	Transcriptional regulator
B1NLA3E_02050	COG0765	amino acid transport
B1NLA3E_02065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B1NLA3E_02070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1NLA3E_02075	COG2966	Psort location CytoplasmicMembrane, score
B1NLA3E_02080	COG3610	response to peptide
B1NLA3E_02090	COG1131	(ABC) transporter
B1NLA3E_02100	COG5002	protein histidine kinase activity
B1NLA3E_02100	COG3850	Histidine kinase
B1NLA3E_02105	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_02115	COG1132	(ABC) transporter
B1NLA3E_02120	COG1132	(ABC) transporter
B1NLA3E_02130	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_02140	COG0004	ammonium transporteR
B1NLA3E_02155	COG1301	dicarboxylic acid transport
B1NLA3E_02160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B1NLA3E_02165	COG3290	protein histidine kinase activity
B1NLA3E_02175	COG5002	protein histidine kinase activity
B1NLA3E_02180	COG0348	domain, Protein
B1NLA3E_02185	COG2770	Histidine kinase
B1NLA3E_02185	COG3437	response regulator, receiver
B1NLA3E_02195	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_02200	COG0626	cystathionine gamma-synthase activity
B1NLA3E_02230	COG4585	Histidine kinase
B1NLA3E_02235	COG2197	response regulator
B1NLA3E_02240	COG2244	polysaccharide biosynthetic process
B1NLA3E_02245	COG0670	Belongs to the BI1 family
B1NLA3E_02250	COG1970	mechanosensitive ion channel activity
B1NLA3E_02255	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B1NLA3E_02265	COG2309	aminopeptidase activity
B1NLA3E_02270	COG0475	glutathione-regulated potassium exporter activity
B1NLA3E_02280	COG0551	DNA topoisomerase type I activity
B1NLA3E_02280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1NLA3E_02300	COG0024	Methionine aminopeptidase
B1NLA3E_02305	COG4840	Belongs to the UPF0435 family
B1NLA3E_02315	COG1295	ribonuclease BN
B1NLA3E_02330	COG2217	Heavy metal translocating P-type atpase
B1NLA3E_02335	COG0477	Major facilitator Superfamily
B1NLA3E_02340	COG0387	Pfam Sodium calcium exchanger
B1NLA3E_02350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1NLA3E_02375	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B1NLA3E_02380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1NLA3E_02390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B1NLA3E_02415	COG0583	DNA-binding transcription factor activity
B1NLA3E_02420	COG2814	Major facilitator Superfamily
B1NLA3E_02425	COG0517	IMP dehydrogenase activity
B1NLA3E_02425	COG0516	GMP reductase activity
B1NLA3E_02430	COG0840	transmembrane signaling receptor activity
B1NLA3E_02440	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
B1NLA3E_02455	COG4807	Protein conserved in bacteria
B1NLA3E_02460	COG2252	PERMEase
B1NLA3E_02490	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B1NLA3E_02495	COG0738	Major facilitator superfamily
B1NLA3E_02505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1NLA3E_02510	COG2610	gluconate transmembrane transporter activity
B1NLA3E_02515	COG1929	Belongs to the glycerate kinase type-1 family
B1NLA3E_02520	COG3835	regulator
B1NLA3E_02525	COG5002	protein histidine kinase activity
B1NLA3E_02570	COG0765	amino acid transport
B1NLA3E_02575	COG1126	abc transporter atp-binding protein
B1NLA3E_02590	COG0583	DNA-binding transcription factor activity
B1NLA3E_02595	COG2814	Major facilitator Superfamily
B1NLA3E_02610	COG3344	reverse transcriptase
B1NLA3E_02620	COG3344	reverse transcriptase
B1NLA3E_02630	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_02640	COG3344	reverse transcriptase
B1NLA3E_02660	COG0454	-acetyltransferase
B1NLA3E_02665	COG2819	hydrolase of the alpha beta superfamily
B1NLA3E_02690	COG1704	LemA family
B1NLA3E_02700	COG0217	transcriptional regulatory protein
B1NLA3E_02710	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_02715	COG5002	protein histidine kinase activity
B1NLA3E_02720	COG1268	BioY protein
B1NLA3E_02725	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B1NLA3E_02730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_02740	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_02745	COG5002	protein histidine kinase activity
B1NLA3E_02750	COG4191	Histidine kinase
B1NLA3E_02785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1NLA3E_02790	COG3300	MHYT domain
B1NLA3E_02790	COG5001	Diguanylate cyclase
B1NLA3E_02800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1NLA3E_02805	COG3459	Glycosyltransferase 36 associated
B1NLA3E_02810	COG2205	protein histidine kinase activity
B1NLA3E_02815	COG1328	CTP reductase activity
B1NLA3E_02825	COG1309	transcriptional regulator
B1NLA3E_02830	COG1131	(ABC) transporter
B1NLA3E_02850	COG2270	Major facilitator Superfamily
B1NLA3E_02885	COG3493	citrate carrier protein
B1NLA3E_02890	COG1113	amino acid transport
B1NLA3E_02895	COG0346	lactoylglutathione lyase activity
B1NLA3E_02900	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B1NLA3E_02905	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B1NLA3E_02925	COG0494	nUDIX hydrolase
B1NLA3E_02960	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_02975	COG0697	spore germination
B1NLA3E_03000	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B1NLA3E_03005	COG1304	FMN binding
B1NLA3E_03010	COG0549	Belongs to the carbamate kinase family
B1NLA3E_03015	COG2508	Transcriptional regulator
B1NLA3E_03050	COG1070	Carbohydrate kinase
B1NLA3E_03065	COG0778	Nitroreductase
B1NLA3E_03080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1NLA3E_03090	COG2132	Multicopper oxidase
B1NLA3E_03095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1NLA3E_03100	COG1742	UPF0060 membrane protein
B1NLA3E_03130	COG1183	phosphatidylcholine synthase activity
B1NLA3E_03135	COG2252	PERMEase
B1NLA3E_03140	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
B1NLA3E_03160	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_03175	COG1585	Membrane protein implicated in regulation of membrane protease activity
B1NLA3E_03180	COG2268	Band 7 protein
B1NLA3E_03185	COG1609	Transcriptional regulator
B1NLA3E_03190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1NLA3E_03200	COG1129	ABC transporter
B1NLA3E_03205	COG1172	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_03210	COG1879	ABC-type sugar transport system periplasmic component
B1NLA3E_03230	COG1132	(ABC) transporter
B1NLA3E_03235	COG0583	DNA-binding transcription factor activity
B1NLA3E_03245	COG0398	Pfam SNARE associated Golgi protein
B1NLA3E_03260	COG4134	Bacterial extracellular solute-binding protein
B1NLA3E_03270	COG4149	molybdate abc transporter
B1NLA3E_03275	COG3842	ATPase activity
B1NLA3E_03285	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B1NLA3E_03300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B1NLA3E_03305	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B1NLA3E_03310	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
B1NLA3E_03310	COG0028	Belongs to the TPP enzyme family
B1NLA3E_03355	COG1988	membrane-bound metal-dependent
B1NLA3E_03360	COG1194	a g-specific adenine glycosylase
B1NLA3E_03370	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_03385	COG3557	Belongs to the UPF0374 family
B1NLA3E_03390	COG1132	(ABC) transporter
B1NLA3E_03400	COG5577	PFAM Coat F domain
B1NLA3E_03405	COG4129	membrane
B1NLA3E_03410	COG0070	glutamate synthase
B1NLA3E_03410	COG0069	glutamate synthase activity
B1NLA3E_03410	COG0067	glutamate synthase
B1NLA3E_03415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1NLA3E_03420	COG4555	ABC transporter
B1NLA3E_03440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B1NLA3E_03445	COG2096	Adenosyltransferase
B1NLA3E_03450	COG0735	belongs to the Fur family
B1NLA3E_03470	COG0469	pyruvate kinase activity
B1NLA3E_03475	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B1NLA3E_03485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B1NLA3E_03490	COG2766	serine protein kinase
B1NLA3E_03500	COG2814	Major facilitator Superfamily
B1NLA3E_03505	COG1809	phosphosulfolactate synthase activity
B1NLA3E_03510	COG0406	alpha-ribazole phosphatase activity
B1NLA3E_03515	COG0175	sulfate reduction
B1NLA3E_03520	COG2046	Belongs to the sulfate adenylyltransferase family
B1NLA3E_03525	COG0529	Catalyzes the synthesis of activated sulfate
B1NLA3E_03530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_03535	COG2718	Belongs to the UPF0229 family
B1NLA3E_03545	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_03555	COG0411	ABC transporter
B1NLA3E_03570	COG0243	molybdopterin cofactor binding
B1NLA3E_03595	COG2223	nitrite transmembrane transporter activity
B1NLA3E_03600	COG4585	Histidine kinase
B1NLA3E_03605	COG2197	response regulator
B1NLA3E_03610	COG4585	Histidine kinase
B1NLA3E_03620	COG5002	protein histidine kinase activity
B1NLA3E_03650	COG0306	phosphate transporter
B1NLA3E_03655	COG1392	Phosphate transport regulator
B1NLA3E_03660	COG0564	pseudouridine synthase activity
B1NLA3E_03670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_03680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1NLA3E_03695	COG2719	SpoVR family
B1NLA3E_03715	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_03720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B1NLA3E_03725	COG1253	flavin adenine dinucleotide binding
B1NLA3E_03730	COG0789	Transcriptional regulator
B1NLA3E_03735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1NLA3E_03740	COG3852	Histidine kinase
B1NLA3E_03765	COG0702	epimerase
B1NLA3E_03780	COG3842	ATPase activity
B1NLA3E_03785	COG2508	Transcriptional regulator
B1NLA3E_03795	COG0189	ligase activity
B1NLA3E_03805	COG0561	phosphatase activity
B1NLA3E_03810	COG1024	Enoyl-CoA hydratase
B1NLA3E_03820	COG4152	abc transporter atp-binding protein
B1NLA3E_03825	COG1668	transmembrane transport
B1NLA3E_03830	COG0420	3'-5' exonuclease activity
B1NLA3E_03835	COG4717	serine-type aminopeptidase activity
B1NLA3E_03850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1NLA3E_03860	COG1846	Transcriptional regulator
B1NLA3E_03880	COG0537	adenosine 5'-monophosphoramidase activity
B1NLA3E_03885	COG1131	(ABC) transporter
B1NLA3E_03890	COG4473	ABC transporter
B1NLA3E_03905	COG0444	Belongs to the ABC transporter superfamily
B1NLA3E_03910	COG4608	Belongs to the ABC transporter superfamily
B1NLA3E_03915	COG0747	negative chemotaxis
B1NLA3E_03935	COG5002	protein histidine kinase activity
B1NLA3E_03940	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_03945	COG1705	Flagellar rod assembly protein muramidase FlgJ
B1NLA3E_03945	COG1388	LysM domain
B1NLA3E_03950	COG0791	NLP P60 protein
B1NLA3E_03950	COG1388	LysM domain
B1NLA3E_03970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_03980	COG3069	C4-dicarboxylate transmembrane transporter activity
B1NLA3E_03985	COG2329	Antibiotic biosynthesis monooxygenase
B1NLA3E_04005	COG1309	transcriptional regulator
B1NLA3E_04010	COG1511	domain protein
B1NLA3E_04020	COG1234	tRNA 3'-trailer cleavage
B1NLA3E_04025	COG0095	Lipoate-protein ligase
B1NLA3E_04030	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_04040	COG4120	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_04045	COG1122	ATPase activity
B1NLA3E_04055	COG1802	Transcriptional regulator
B1NLA3E_04060	COG2084	Dehydrogenase
B1NLA3E_04090	COG0697	spore germination
B1NLA3E_04095	COG0604	alcohol dehydrogenase
B1NLA3E_04110	COG1114	Component of the transport system for branched-chain amino acids
B1NLA3E_04115	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_04125	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B1NLA3E_04135	COG0501	Belongs to the peptidase M48B family
B1NLA3E_04145	COG4903	ComK protein
B1NLA3E_04155	COG1316	TRANSCRIPTIONal
B1NLA3E_04160	COG0398	Pfam SNARE associated Golgi protein
B1NLA3E_04170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_04180	COG5577	PFAM Coat F domain
B1NLA3E_04190	COG0411	ABC transporter
B1NLA3E_04195	COG0410	ABC transporter
B1NLA3E_04200	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_04210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_04215	COG2267	carboxylic ester hydrolase activity
B1NLA3E_04220	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_04240	COG1113	amino acid transport
B1NLA3E_04245	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B1NLA3E_04245	COG2508	Transcriptional regulator
B1NLA3E_04250	COG0686	Belongs to the AlaDH PNT family
B1NLA3E_04255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B1NLA3E_04260	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_04270	COG2308	Evidence 4 Homologs of previously reported genes of
B1NLA3E_04280	COG1305	Transglutaminase-like
B1NLA3E_04285	COG1268	BioY protein
B1NLA3E_04305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B1NLA3E_04320	COG0367	asparagine synthase
B1NLA3E_04345	COG1132	(ABC) transporter
B1NLA3E_04350	COG3944	biosynthesis protein
B1NLA3E_04355	COG0489	protein tyrosine kinase activity
B1NLA3E_04365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_04380	COG1216	Glycosyl transferase, family 2
B1NLA3E_04385	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_04390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1NLA3E_04390	COG0463	Glycosyl transferase, family 2
B1NLA3E_04400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1NLA3E_04405	COG0110	maltose O-acetyltransferase activity
B1NLA3E_04410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1NLA3E_04435	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_04450	COG1442	glycosyl transferase family 8
B1NLA3E_04450	COG1216	Glycosyl transferase, family 2
B1NLA3E_04475	COG4372	Transposase
B1NLA3E_04490	COG1132	(ABC) transporter
B1NLA3E_04515	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B1NLA3E_04520	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_04555	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_04575	COG0367	asparagine synthase
B1NLA3E_04585	COG1874	Beta-galactosidase
B1NLA3E_04585	COG0366	Alpha amylase catalytic
B1NLA3E_04590	COG1666	GTP binding
B1NLA3E_04595	COG2996	Protein conserved in bacteria
B1NLA3E_04600	COG1307	EDD domain protein, DegV family
B1NLA3E_04605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_04620	COG0561	phosphatase activity
B1NLA3E_04625	COG2151	metal-sulfur cluster biosynthetic enzyme
B1NLA3E_04635	COG1131	(ABC) transporter
B1NLA3E_04640	COG0842	Transport permease protein
B1NLA3E_04640	COG1511	domain protein
B1NLA3E_04645	COG0842	Transport permease protein
B1NLA3E_04655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_04660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1NLA3E_04665	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B1NLA3E_04670	COG0303	'Molybdopterin
B1NLA3E_04675	COG1763	Mo-molybdopterin cofactor biosynthetic process
B1NLA3E_04685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_04690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B1NLA3E_04720	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B1NLA3E_04740	COG2267	carboxylic ester hydrolase activity
B1NLA3E_04755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_04760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1NLA3E_04765	COG5504	Zn-dependent protease
B1NLA3E_04775	COG0180	Tryptophanyl-tRNA synthetase
B1NLA3E_04780	COG4166	transmembrane transport
B1NLA3E_04785	COG0601	transmembrane transport
B1NLA3E_04790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1NLA3E_04795	COG0444	Belongs to the ABC transporter superfamily
B1NLA3E_04800	COG4608	Belongs to the ABC transporter superfamily
B1NLA3E_04810	COG1393	Belongs to the ArsC family
B1NLA3E_04815	COG4862	establishment of competence for transformation
B1NLA3E_04820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_04830	COG1164	Oligoendopeptidase f
B1NLA3E_04845	COG2346	COG2346, Truncated hemoglobins
B1NLA3E_04850	COG4116	CYTH
B1NLA3E_04855	COG2357	RelA SpoT domain protein
B1NLA3E_04860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B1NLA3E_04865	COG0564	pseudouridine synthase activity
B1NLA3E_04870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1NLA3E_04875	COG0475	glutathione-regulated potassium exporter activity
B1NLA3E_04875	COG0569	domain protein
B1NLA3E_04880	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B1NLA3E_04900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_04915	COG0210	DNA helicase
B1NLA3E_04920	COG2153	protein acetylation
B1NLA3E_04925	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B1NLA3E_04935	COG0247	lactate metabolic process
B1NLA3E_04940	COG1139	Iron-sulfur cluster binding protein
B1NLA3E_04945	COG1556	Lactate utilization protein
B1NLA3E_04955	COG2146	nitrite reductase [NAD(P)H] activity
B1NLA3E_04955	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B1NLA3E_04985	COG0824	Thioesterase
B1NLA3E_05010	COG1216	Glycosyl transferase, family 2
B1NLA3E_05010	COG0463	Glycosyl transferase, family 2
B1NLA3E_05035	COG0702	epimerase
B1NLA3E_05040	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
B1NLA3E_05045	COG1846	Transcriptional regulator
B1NLA3E_05075	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B1NLA3E_05085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1NLA3E_05090	COG2814	Major facilitator Superfamily
B1NLA3E_05095	COG2814	Major facilitator Superfamily
B1NLA3E_05100	COG0583	DNA-binding transcription factor activity
B1NLA3E_05110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1NLA3E_05115	COG2151	metal-sulfur cluster biosynthetic enzyme
B1NLA3E_05125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1NLA3E_05135	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B1NLA3E_05145	COG1191	sigma factor activity
B1NLA3E_05160	COG0247	lactate metabolic process
B1NLA3E_05165	COG0277	FAD linked oxidase domain protein
B1NLA3E_05170	COG3835	regulator
B1NLA3E_05190	COG1620	l-lactate permease
B1NLA3E_05195	COG2186	Transcriptional regulator
B1NLA3E_05200	COG0247	lactate metabolic process
B1NLA3E_05205	COG1139	Iron-sulfur cluster binding protein
B1NLA3E_05210	COG1556	Lactate utilization protein
B1NLA3E_05245	COG5002	protein histidine kinase activity
B1NLA3E_05255	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B1NLA3E_05260	COG0674	pyruvate-flavodoxin oxidoreductase activity
B1NLA3E_05265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1NLA3E_05270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1NLA3E_05285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_05290	COG0644	oxidoreductase
B1NLA3E_05305	COG2972	Histidine kinase
B1NLA3E_05310	COG2201	protein-glutamate methylesterase activity
B1NLA3E_05320	COG1175	transmembrane transport
B1NLA3E_05335	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B1NLA3E_05345	COG0671	phosphoesterase, PA-phosphatase related
B1NLA3E_05355	COG1309	transcriptional regulator
B1NLA3E_05365	COG2318	DinB family
B1NLA3E_05370	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_05375	COG5002	protein histidine kinase activity
B1NLA3E_05380	COG1136	(ABC) transporter
B1NLA3E_05385	COG0577	efflux transmembrane transporter activity
B1NLA3E_05420	COG0697	spore germination
B1NLA3E_05435	COG0577	efflux transmembrane transporter activity
B1NLA3E_05440	COG1136	(ABC) transporter
B1NLA3E_05450	COG3850	Histidine kinase
B1NLA3E_05450	COG5002	protein histidine kinase activity
B1NLA3E_05480	COG0456	acetyltransferase
B1NLA3E_05485	COG0456	acetyltransferase
B1NLA3E_05495	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1NLA3E_05515	COG2207	Transcriptional regulator
B1NLA3E_05520	COG0667	Aldo Keto reductase
B1NLA3E_05525	COG0656	L-ascorbic acid biosynthetic process
B1NLA3E_05530	COG2223	nitrite transmembrane transporter activity
B1NLA3E_05535	COG1846	Transcriptional regulator
B1NLA3E_05545	COG3949	Membrane
B1NLA3E_05555	COG4873	Protein conserved in bacteria
B1NLA3E_05565	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_05570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1NLA3E_05580	COG2084	Dehydrogenase
B1NLA3E_05590	COG0436	Aminotransferase
B1NLA3E_05595	COG0598	Magnesium transport protein CorA
B1NLA3E_05605	COG1408	metallophosphoesterase
B1NLA3E_05610	COG4990	cell redox homeostasis
B1NLA3E_05615	COG2200	EAL domain
B1NLA3E_05635	COG2323	membrane
B1NLA3E_05655	COG4703	Protein of unknown function (DUF1797)
B1NLA3E_05660	COG0517	IMP dehydrogenase activity
B1NLA3E_05665	COG2814	Major facilitator Superfamily
B1NLA3E_05670	COG0583	DNA-binding transcription factor activity
B1NLA3E_05680	COG1473	amidohydrolase
B1NLA3E_05685	COG0450	alkyl hydroperoxide reductase
B1NLA3E_05695	COG0569	domain protein
B1NLA3E_05700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1NLA3E_05710	COG0561	phosphatase activity
B1NLA3E_05715	COG0242	peptide deformylase activity
B1NLA3E_05720	COG0497	DNA recombination
B1NLA3E_05730	COG0022	dehydrogenase e1 component
B1NLA3E_05765	COG1982	Orn Lys Arg decarboxylase major
B1NLA3E_05775	COG4476	Belongs to the UPF0223 family
B1NLA3E_05780	COG4493	Belongs to the UPF0637 family
B1NLA3E_05790	COG0483	inositol monophosphate 1-phosphatase activity
B1NLA3E_05815	COG4896	Protein conserved in bacteria
B1NLA3E_05845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B1NLA3E_05850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B1NLA3E_05855	COG4838	Belongs to the UPF0358 family
B1NLA3E_05860	COG0772	Belongs to the SEDS family
B1NLA3E_05865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B1NLA3E_05870	COG1612	heme a metabolic process
B1NLA3E_05900	COG3336	cytochrome c oxidase
B1NLA3E_05925	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B1NLA3E_05940	COG2340	Cysteine-rich secretory protein family
B1NLA3E_05970	COG3679	Belongs to the UPF0342 family
B1NLA3E_05975	COG4471	UPF0298 protein
B1NLA3E_05990	COG0742	ribosomal rna small subunit methyltransferase
B1NLA3E_05995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B1NLA3E_06000	COG3314	Sporulation integral membrane protein YlbJ
B1NLA3E_06005	COG1752	Esterase of the alpha-beta hydrolase superfamily
B1NLA3E_06010	COG3480	Lon protease (S16) C-terminal proteolytic domain
B1NLA3E_06015	COG1323	Belongs to the UPF0348 family
B1NLA3E_06020	COG1399	metal-binding, possibly nucleic acid-binding protein
B1NLA3E_06030	COG1024	Enoyl-CoA hydratase
B1NLA3E_06040	COG0454	-acetyltransferase
B1NLA3E_06045	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B1NLA3E_06055	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B1NLA3E_06060	COG2001	Belongs to the MraZ family
B1NLA3E_06065	COG0275	rRNA processing
B1NLA3E_06070	COG4839	cell division protein FtsL
B1NLA3E_06080	COG0768	penicillin binding
B1NLA3E_06095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1NLA3E_06105	COG0772	Belongs to the SEDS family
B1NLA3E_06115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B1NLA3E_06120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B1NLA3E_06125	COG3879	Bacterial protein of unknown function (DUF881)
B1NLA3E_06130	COG3879	Bacterial protein of unknown function (DUF881)
B1NLA3E_06135	COG3856	small basic protein
B1NLA3E_06140	COG0849	cell division
B1NLA3E_06145	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B1NLA3E_06155	COG1191	sigma factor activity
B1NLA3E_06165	COG1191	sigma factor activity
B1NLA3E_06170	COG1873	PFAM PRC-barrel domain
B1NLA3E_06180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B1NLA3E_06185	COG1799	cell septum assembly
B1NLA3E_06190	COG0762	integral membrane protein
B1NLA3E_06195	COG2302	S4 RNA-binding domain
B1NLA3E_06200	COG3599	regulation of cell shape
B1NLA3E_06205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B1NLA3E_06210	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B1NLA3E_06220	COG0564	pseudouridine synthase activity
B1NLA3E_06225	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B1NLA3E_06255	COG0543	2 iron, 2 sulfur cluster binding
B1NLA3E_06260	COG0167	dihydroorotate dehydrogenase activity
B1NLA3E_06265	COG0284	orotidine-5'-phosphate decarboxylase activity
B1NLA3E_06270	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B1NLA3E_06285	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1NLA3E_06290	COG1561	YicC-like family, N-terminal region
B1NLA3E_06295	COG2052	Domain of unknown function (DUF370)
B1NLA3E_06300	COG0194	GDP metabolic process
B1NLA3E_06310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B1NLA3E_06315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B1NLA3E_06325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1NLA3E_06330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B1NLA3E_06330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1NLA3E_06335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1NLA3E_06340	COG0631	protein serine/threonine phosphatase activity
B1NLA3E_06345	COG0515	serine threonine protein kinase
B1NLA3E_06345	COG2815	serine threonine protein kinase
B1NLA3E_06350	COG1162	GTPase activity
B1NLA3E_06355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1NLA3E_06360	COG1564	THIamine pyrophosphokinase
B1NLA3E_06370	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1NLA3E_06375	COG1302	Protein conserved in bacteria
B1NLA3E_06380	COG1461	Dihydroxyacetone kinase
B1NLA3E_06385	COG1760	l-serine dehydratase
B1NLA3E_06390	COG1760	l-serine dehydratase
B1NLA3E_06395	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B1NLA3E_06400	COG1349	DNA-binding transcription factor activity
B1NLA3E_06405	COG0416	fatty acid biosynthetic process
B1NLA3E_06410	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B1NLA3E_06415	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_06420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1NLA3E_06425	COG0571	ribonuclease III activity
B1NLA3E_06430	COG1196	nuclear chromosome segregation
B1NLA3E_06435	COG0552	protein localization to endoplasmic reticulum
B1NLA3E_06455	COG0754	glutathionylspermidine amidase activity
B1NLA3E_06460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B1NLA3E_06465	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B1NLA3E_06470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B1NLA3E_06475	COG0228	four-way junction DNA binding
B1NLA3E_06480	COG1837	Belongs to the UPF0109 family
B1NLA3E_06490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B1NLA3E_06495	COG0336	Belongs to the RNA methyltransferase TrmD family
B1NLA3E_06525	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B1NLA3E_06530	COG0758	DNA mediated transformation
B1NLA3E_06535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1NLA3E_06540	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B1NLA3E_06545	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_06550	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B1NLA3E_06555	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B1NLA3E_06560	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B1NLA3E_06580	COG0528	UMP kinase activity
B1NLA3E_06585	COG0233	cytoplasmic translational termination
B1NLA3E_06595	COG4589	Belongs to the CDS family
B1NLA3E_06600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B1NLA3E_06605	COG0750	zinc metalloprotease
B1NLA3E_06615	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_06620	COG0779	Required for maturation of 30S ribosomal subunits
B1NLA3E_06625	COG0195	Participates in both transcription termination and antitermination
B1NLA3E_06630	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B1NLA3E_06635	COG1358	cellular component organization or biogenesis
B1NLA3E_06645	COG1550	Protein conserved in bacteria
B1NLA3E_06655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B1NLA3E_06660	COG0196	riboflavin kinase activity
B1NLA3E_06665	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B1NLA3E_06670	COG1185	polyribonucleotide nucleotidyltransferase activity
B1NLA3E_06675	COG0726	polysaccharide deacetylase
B1NLA3E_06680	COG0612	Peptidase, M16
B1NLA3E_06685	COG1873	PFAM PRC-barrel domain
B1NLA3E_06690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1NLA3E_06695	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B1NLA3E_06700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B1NLA3E_06705	COG0527	aspartate kinase activity
B1NLA3E_06710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1NLA3E_06715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1NLA3E_06720	COG0740	serine-type endopeptidase activity
B1NLA3E_06730	COG1674	ftsk spoiiie
B1NLA3E_06730	COG4980	gas vesicle protein
B1NLA3E_06735	COG2188	Transcriptional regulator
B1NLA3E_06740	COG1744	ABC transporter substrate-binding protein PnrA-like
B1NLA3E_06760	COG0612	Peptidase, M16
B1NLA3E_06765	COG0612	Peptidase, M16
B1NLA3E_06770	COG0300	oxidoreductase activity
B1NLA3E_06785	COG1426	Protein conserved in bacteria
B1NLA3E_06790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1NLA3E_06795	COG1058	Belongs to the CinA family
B1NLA3E_06795	COG1546	Belongs to the CinA family
B1NLA3E_06800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B1NLA3E_06805	COG1418	mRNA catabolic process
B1NLA3E_06810	COG1692	metallophosphoesterase
B1NLA3E_06815	COG2359	stage V sporulation protein S
B1NLA3E_06820	COG0674	pyruvate-flavodoxin oxidoreductase activity
B1NLA3E_06820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B1NLA3E_06825	COG1013	pyruvate-flavodoxin oxidoreductase activity
B1NLA3E_06830	COG1349	DNA-binding transcription factor activity
B1NLA3E_06835	COG1105	Belongs to the carbohydrate kinase PfkB family
B1NLA3E_06840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_06840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_06840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_06845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1NLA3E_06850	COG4550	Control of competence regulator ComK, YlbF/YmcA
B1NLA3E_06865	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B1NLA3E_06870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B1NLA3E_06880	COG1077	Cell shape determining protein MreB Mrl
B1NLA3E_06885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B1NLA3E_06890	COG1923	regulation of RNA biosynthetic process
B1NLA3E_06900	COG0464	growth
B1NLA3E_06905	COG2860	membrane
B1NLA3E_06910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B1NLA3E_06915	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B1NLA3E_06920	COG0789	Transcriptional regulator
B1NLA3E_06925	COG0174	glutamine synthetase
B1NLA3E_06930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B1NLA3E_06935	COG1388	LysM domain
B1NLA3E_06940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B1NLA3E_06950	COG0477	Major facilitator Superfamily
B1NLA3E_06960	COG1271	oxidase subunit
B1NLA3E_06965	COG1294	oxidase, subunit
B1NLA3E_06975	COG3763	UPF0154 protein
B1NLA3E_06980	COG3883	PFAM NLP P60 protein
B1NLA3E_06980	COG0791	NLP P60 protein
B1NLA3E_06985	COG1132	(ABC) transporter
B1NLA3E_06990	COG1132	(ABC) transporter
B1NLA3E_07000	COG0785	Cytochrome C biogenesis protein
B1NLA3E_07005	COG2201	protein-glutamate methylesterase activity
B1NLA3E_07010	COG4846	Membrane protein involved in cytochrome C biogenesis
B1NLA3E_07050	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_07100	COG0277	FAD linked oxidase domain protein
B1NLA3E_07120	COG1136	(ABC) transporter
B1NLA3E_07125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1NLA3E_07135	COG1454	alcohol dehydrogenase
B1NLA3E_07135	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_07145	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B1NLA3E_07175	COG1131	(ABC) transporter
B1NLA3E_07200	COG5002	protein histidine kinase activity
B1NLA3E_07215	COG0675	Transposase, IS605 OrfB family
B1NLA3E_07230	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B1NLA3E_07235	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B1NLA3E_07240	COG3639	organic phosphonate transmembrane transporter activity
B1NLA3E_07250	COG1309	transcriptional regulator
B1NLA3E_07260	COG0667	Aldo Keto reductase
B1NLA3E_07265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B1NLA3E_07270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1NLA3E_07275	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_07280	COG2186	Transcriptional regulator
B1NLA3E_07285	COG1063	alcohol dehydrogenase
B1NLA3E_07295	COG0205	6-phosphofructokinase activity
B1NLA3E_07305	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_07310	COG5002	protein histidine kinase activity
B1NLA3E_07320	COG0577	efflux transmembrane transporter activity
B1NLA3E_07330	COG1136	(ABC) transporter
B1NLA3E_07340	COG1113	amino acid transport
B1NLA3E_07375	COG0346	lactoylglutathione lyase activity
B1NLA3E_07390	COG3384	dioxygenase
B1NLA3E_07425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1NLA3E_07430	COG1346	cytolysis
B1NLA3E_07435	COG1380	Effector of murein hydrolase LrgA
B1NLA3E_07440	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B1NLA3E_07460	COG1113	amino acid transport
B1NLA3E_07465	COG0672	)-iron permease
B1NLA3E_07480	COG1136	(ABC) transporter
B1NLA3E_07480	COG0577	efflux transmembrane transporter activity
B1NLA3E_07485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1NLA3E_07490	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_07495	COG5002	protein histidine kinase activity
B1NLA3E_07495	COG3850	Histidine kinase
B1NLA3E_07500	COG0583	DNA-binding transcription factor activity
B1NLA3E_07505	COG2271	Major facilitator Superfamily
B1NLA3E_07515	COG0644	oxidoreductase
B1NLA3E_07525	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_07530	COG2086	electron transfer activity
B1NLA3E_07535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_07540	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_07545	COG2271	Major facilitator Superfamily
B1NLA3E_07565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_07580	COG1376	ErfK ybiS ycfS ynhG family protein
B1NLA3E_07585	COG0322	excinuclease ABC activity
B1NLA3E_07590	COG4191	Histidine kinase
B1NLA3E_07615	COG1278	Cold shock
B1NLA3E_07625	COG0419	ATPase involved in DNA repair
B1NLA3E_07635	COG1252	NADH dehydrogenase
B1NLA3E_07640	COG0535	radical SAM domain protein
B1NLA3E_07645	COG2814	Major facilitator Superfamily
B1NLA3E_07665	COG2871	sodium ion transport
B1NLA3E_07670	COG1414	Transcriptional regulator
B1NLA3E_07695	COG0004	ammonium transporteR
B1NLA3E_07700	COG0196	riboflavin kinase activity
B1NLA3E_07720	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_07725	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_07730	COG0439	Biotin carboxylase
B1NLA3E_07735	COG0511	ligase activity, forming carbon-carbon bonds
B1NLA3E_07740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1NLA3E_07745	COG1024	Enoyl-CoA hydratase
B1NLA3E_07750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1NLA3E_07755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B1NLA3E_07760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1NLA3E_07765	COG0352	thiamine-phosphate diphosphorylase activity
B1NLA3E_07775	COG2104	thiamine diphosphate biosynthetic process
B1NLA3E_07780	COG2022	thiamine diphosphate biosynthetic process
B1NLA3E_07785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_07800	COG3437	response regulator, receiver
B1NLA3E_07800	COG2770	Histidine kinase
B1NLA3E_07805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_07810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B1NLA3E_07820	COG0681	Belongs to the peptidase S26 family
B1NLA3E_07840	COG5583	Uncharacterized small protein (DUF2292)
B1NLA3E_07845	COG1116	anion transmembrane transporter activity
B1NLA3E_07850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_07855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_07860	COG0431	NADPH-dependent FMN reductase
B1NLA3E_07865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_07875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B1NLA3E_07885	COG1119	ATPase activity
B1NLA3E_07895	COG1714	RDD family
B1NLA3E_07905	COG0175	sulfate reduction
B1NLA3E_07910	COG0306	phosphate transporter
B1NLA3E_07920	COG0529	Catalyzes the synthesis of activated sulfate
B1NLA3E_07925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_07960	COG2340	Cysteine-rich secretory protein family
B1NLA3E_07965	COG1363	Peptidase, m42
B1NLA3E_07975	COG1368	sulfuric ester hydrolase activity
B1NLA3E_08005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_08015	COG0084	hydrolase, TatD family'
B1NLA3E_08025	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_08045	COG0604	alcohol dehydrogenase
B1NLA3E_08050	COG2116	formate transmembrane transporter activity
B1NLA3E_08060	COG1309	transcriptional regulator
B1NLA3E_08115	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1NLA3E_08120	COG0561	phosphatase activity
B1NLA3E_08130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B1NLA3E_08140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1NLA3E_08150	COG0668	transmembrane transport
B1NLA3E_08160	COG0531	amino acid
B1NLA3E_08170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B1NLA3E_08175	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1NLA3E_08185	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B1NLA3E_08195	COG4208	sulfate ABC transporter
B1NLA3E_08205	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B1NLA3E_08225	COG0697	spore germination
B1NLA3E_08230	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B1NLA3E_08240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_08245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B1NLA3E_08250	COG1116	anion transmembrane transporter activity
B1NLA3E_08255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_08260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_08265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1NLA3E_08285	COG2323	membrane
B1NLA3E_08290	COG0583	DNA-binding transcription factor activity
B1NLA3E_08295	COG0067	glutamate synthase
B1NLA3E_08295	COG0069	glutamate synthase activity
B1NLA3E_08295	COG0070	glutamate synthase
B1NLA3E_08300	COG0493	'glutamate synthase
B1NLA3E_08305	COG1388	LysM domain
B1NLA3E_08305	COG3942	CHAP domain
B1NLA3E_08315	COG2171	N-acyltransferase activity
B1NLA3E_08320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_08325	COG1346	cytolysis
B1NLA3E_08335	COG0583	DNA-binding transcription factor activity
B1NLA3E_08345	COG1396	sequence-specific DNA binding
B1NLA3E_08350	COG0252	asparaginase activity
B1NLA3E_08360	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B1NLA3E_08370	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B1NLA3E_08380	COG1408	metallophosphoesterase
B1NLA3E_08385	COG3541	Predicted nucleotidyltransferase
B1NLA3E_08390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_08390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_08390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_08400	COG2135	peptidase activity
B1NLA3E_08405	COG0531	amino acid
B1NLA3E_08410	COG1278	Cold shock
B1NLA3E_08475	COG2871	sodium ion transport
B1NLA3E_08495	COG1914	H( )-stimulated, divalent metal cation uptake system
B1NLA3E_08505	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1NLA3E_08535	COG0596	Alpha beta hydrolase
B1NLA3E_08545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1NLA3E_08550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_08555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_08560	COG0686	Belongs to the AlaDH PNT family
B1NLA3E_08565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_08570	COG0765	amino acid transport
B1NLA3E_08575	COG1126	abc transporter atp-binding protein
B1NLA3E_08580	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_08585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1NLA3E_08600	COG0686	Belongs to the AlaDH PNT family
B1NLA3E_08610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_08615	COG0765	amino acid transport
B1NLA3E_08620	COG1126	abc transporter atp-binding protein
B1NLA3E_08625	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_08640	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1NLA3E_08645	COG0561	phosphatase activity
B1NLA3E_08650	COG1349	DNA-binding transcription factor activity
B1NLA3E_08665	COG1858	cytochrome C peroxidase
B1NLA3E_08685	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_08700	COG5434	Belongs to the glycosyl hydrolase 28 family
B1NLA3E_08725	COG0798	PFAM Bile acid sodium symporter
B1NLA3E_08730	COG0640	Transcriptional regulator
B1NLA3E_08735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1NLA3E_08755	COG2226	methyltransferase
B1NLA3E_08780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1NLA3E_08790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_08795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_08800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B1NLA3E_08810	COG0456	acetyltransferase
B1NLA3E_08810	COG0454	-acetyltransferase
B1NLA3E_08815	COG1473	amidohydrolase
B1NLA3E_08825	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_08830	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_08835	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_08850	COG3655	Transcriptional regulator
B1NLA3E_08860	COG0675	Transposase, IS605 OrfB family
B1NLA3E_08875	COG0196	riboflavin kinase activity
B1NLA3E_08890	COG0730	response to heat
B1NLA3E_08895	COG2733	membrane
B1NLA3E_08910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1NLA3E_08920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_08925	COG0765	amino acid transport
B1NLA3E_08930	COG1126	abc transporter atp-binding protein
B1NLA3E_08935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1NLA3E_08940	COG0194	GDP metabolic process
B1NLA3E_08945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B1NLA3E_08955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B1NLA3E_08965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1NLA3E_08980	COG1231	oxidoreductase activity
B1NLA3E_09010	COG4319	ketosteroid isomerase
B1NLA3E_09020	COG0156	8-amino-7-oxononanoate synthase activity
B1NLA3E_09035	COG0004	ammonium transporteR
B1NLA3E_09040	COG0517	IMP dehydrogenase activity
B1NLA3E_09040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B1NLA3E_09045	COG2723	6-phospho-beta-galactosidase activity
B1NLA3E_09050	COG2814	Major facilitator Superfamily
B1NLA3E_09065	COG3655	Transcriptional regulator
B1NLA3E_09070	COG0675	Transposase, IS605 OrfB family
B1NLA3E_09090	COG1846	Transcriptional regulator
B1NLA3E_09095	COG0386	Belongs to the glutathione peroxidase family
B1NLA3E_09105	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B1NLA3E_09110	COG4085	toxin activity
B1NLA3E_09110	COG0737	Belongs to the 5'-nucleotidase family
B1NLA3E_09110	COG1525	nuclease
B1NLA3E_09115	COG0137	argininosuccinate synthase activity
B1NLA3E_09135	COG2755	lipolytic protein G-D-S-L family
B1NLA3E_09135	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B1NLA3E_09175	COG2364	Membrane
B1NLA3E_09185	COG1414	Transcriptional regulator
B1NLA3E_09200	COG2186	Transcriptional regulator
B1NLA3E_09205	COG0006	proline dipeptidase activity
B1NLA3E_09225	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_09230	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_09235	COG4638	Rieske (2fe-2S)
B1NLA3E_09255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_09270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1NLA3E_09275	COG0196	riboflavin kinase activity
B1NLA3E_09305	COG1942	4-Oxalocrotonate Tautomerase
B1NLA3E_09345	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_09360	COG0484	heat shock protein binding
B1NLA3E_09375	COG1061	Type III restriction enzyme res subunit
B1NLA3E_09380	COG0537	adenosine 5'-monophosphoramidase activity
B1NLA3E_09405	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_09435	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_09445	COG3275	phosphorelay sensor kinase activity
B1NLA3E_09450	COG3279	Response regulator of the LytR AlgR family
B1NLA3E_09455	COG2223	nitrite transmembrane transporter activity
B1NLA3E_09515	COG2249	NAD(P)H dehydrogenase (quinone) activity
B1NLA3E_09535	COG2814	Major facilitator Superfamily
B1NLA3E_09540	COG1733	regulation of RNA biosynthetic process
B1NLA3E_09545	COG2814	Major facilitator Superfamily
B1NLA3E_09550	COG1309	transcriptional regulator
B1NLA3E_09615	COG3773	Cell wall hydrolase
B1NLA3E_09625	COG0662	Cupin 2, conserved barrel domain protein
B1NLA3E_09650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_09675	COG2267	carboxylic ester hydrolase activity
B1NLA3E_09680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B1NLA3E_09695	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1NLA3E_09710	COG0531	amino acid
B1NLA3E_09725	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1NLA3E_09730	COG0569	domain protein
B1NLA3E_09750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B1NLA3E_09755	COG2818	Glycosylase
B1NLA3E_09760	COG0531	amino acid
B1NLA3E_09765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_09775	COG2204	response regulator
B1NLA3E_09780	COG3852	Histidine kinase
B1NLA3E_09790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1NLA3E_09800	COG1959	2 iron, 2 sulfur cluster binding
B1NLA3E_09805	COG2910	NAD(P)H-binding
B1NLA3E_09810	COG2249	NAD(P)H dehydrogenase (quinone) activity
B1NLA3E_09815	COG3275	phosphorelay sensor kinase activity
B1NLA3E_09820	COG3279	Response regulator of the LytR AlgR family
B1NLA3E_09825	COG1966	Carbon starvation protein
B1NLA3E_09840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1NLA3E_09870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1NLA3E_09895	COG1090	epimerase
B1NLA3E_09900	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_09900	COG1454	alcohol dehydrogenase
B1NLA3E_09905	COG0701	Predicted permease
B1NLA3E_09910	COG3689	TIGRFAM TIGR03943 family protein
B1NLA3E_09915	COG0803	Belongs to the bacterial solute-binding protein 9 family
B1NLA3E_09920	COG3583	domain protein
B1NLA3E_09920	COG3584	3D domain protein
B1NLA3E_09935	COG0675	Transposase, IS605 OrfB family
B1NLA3E_09960	COG2186	Transcriptional regulator
B1NLA3E_09975	COG2822	iron ion transport
B1NLA3E_09980	COG2837	iron assimilation
B1NLA3E_10000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B1NLA3E_10005	COG0390	transport system, permease component
B1NLA3E_10020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_10025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_10030	COG1116	anion transmembrane transporter activity
B1NLA3E_10040	COG0439	Biotin carboxylase
B1NLA3E_10045	COG3665	Urea carboxylase-associated protein
B1NLA3E_10055	COG0531	amino acid
B1NLA3E_10070	COG0596	Alpha beta hydrolase
B1NLA3E_10080	COG2203	Gaf domain
B1NLA3E_10080	COG5001	Diguanylate cyclase
B1NLA3E_10080	COG4251	negative regulation of phosphorylation
B1NLA3E_10080	COG3706	GGDEF domain
B1NLA3E_10100	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_10120	COG1959	2 iron, 2 sulfur cluster binding
B1NLA3E_10140	COG1725	Transcriptional regulator
B1NLA3E_10150	COG4191	Histidine kinase
B1NLA3E_10155	COG2204	response regulator
B1NLA3E_10170	COG0720	synthase
B1NLA3E_10180	COG0302	gtp cyclohydrolase
B1NLA3E_10190	COG2861	carbohydrate metabolic process
B1NLA3E_10195	COG0561	phosphatase activity
B1NLA3E_10215	COG1566	PFAM secretion protein HlyD family protein
B1NLA3E_10230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_10240	COG0789	Transcriptional regulator
B1NLA3E_10250	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B1NLA3E_10260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_10265	COG2146	nitrite reductase [NAD(P)H] activity
B1NLA3E_10270	COG1587	Uroporphyrinogen-III synthase
B1NLA3E_10270	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1NLA3E_10285	COG0527	aspartate kinase activity
B1NLA3E_10290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1NLA3E_10295	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B1NLA3E_10300	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B1NLA3E_10310	COG0737	Belongs to the 5'-nucleotidase family
B1NLA3E_10315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B1NLA3E_10325	COG1024	Enoyl-CoA hydratase
B1NLA3E_10330	COG0561	phosphatase activity
B1NLA3E_10340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1NLA3E_10345	COG2814	Major facilitator Superfamily
B1NLA3E_10365	COG0675	Transposase, IS605 OrfB family
B1NLA3E_10380	COG1280	lysine exporter protein (LysE YggA)
B1NLA3E_10385	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_10395	COG0463	Glycosyl transferase, family 2
B1NLA3E_10420	COG1802	Transcriptional regulator
B1NLA3E_10430	COG0129	dihydroxy-acid dehydratase activity
B1NLA3E_10435	COG2755	lipolytic protein G-D-S-L family
B1NLA3E_10440	COG1131	(ABC) transporter
B1NLA3E_10445	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B1NLA3E_10455	COG2814	Major facilitator Superfamily
B1NLA3E_10465	COG3123	guanosine phosphorylase activity
B1NLA3E_10500	COG0450	alkyl hydroperoxide reductase
B1NLA3E_10505	COG3973	AAA domain
B1NLA3E_10530	COG0488	(ABC) transporter
B1NLA3E_10560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1NLA3E_10565	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_10570	COG5002	protein histidine kinase activity
B1NLA3E_10570	COG3850	Histidine kinase
B1NLA3E_10575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_10615	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B1NLA3E_10620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_10640	COG0824	Thioesterase
B1NLA3E_10650	COG4841	protein insertion into membrane
B1NLA3E_10665	COG5002	protein histidine kinase activity
B1NLA3E_10670	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B1NLA3E_10675	COG3858	chitin binding
B1NLA3E_10680	COG1832	CoA-binding protein
B1NLA3E_10685	COG0187	DNA topoisomerase II activity
B1NLA3E_10690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1NLA3E_10730	COG2368	4-hydroxyphenylacetate
B1NLA3E_10750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1NLA3E_10770	COG0716	FMN binding
B1NLA3E_10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_10780	COG2030	dehydratase
B1NLA3E_10795	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_10800	COG3243	poly(R)-hydroxyalkanoic acid synthase
B1NLA3E_10810	COG0577	efflux transmembrane transporter activity
B1NLA3E_10815	COG1136	(ABC) transporter
B1NLA3E_10825	COG1131	(ABC) transporter
B1NLA3E_10830	COG1725	Transcriptional regulator
B1NLA3E_10835	COG0791	NLP P60 protein
B1NLA3E_10835	COG1388	LysM domain
B1NLA3E_10840	COG3858	chitin binding
B1NLA3E_10855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1NLA3E_10860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_10865	COG0010	Belongs to the arginase family
B1NLA3E_10870	COG1228	amidohydrolase
B1NLA3E_10875	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B1NLA3E_10880	COG2986	histidine ammonia-lyase
B1NLA3E_10895	COG2814	Major facilitator Superfamily
B1NLA3E_10900	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_10905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1NLA3E_10915	COG1183	phosphatidylcholine synthase activity
B1NLA3E_10920	COG0726	polysaccharide deacetylase
B1NLA3E_10925	COG2197	response regulator
B1NLA3E_10930	COG4585	Histidine kinase
B1NLA3E_10935	COG3239	Fatty acid desaturase
B1NLA3E_10940	COG4948	Mandelate Racemase Muconate Lactonizing
B1NLA3E_10950	COG0833	amino acid
B1NLA3E_10955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1NLA3E_10955	COG0426	domain, Protein
B1NLA3E_10965	COG1024	Enoyl-CoA hydratase
B1NLA3E_10970	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_10990	COG3104	oligopeptide transport
B1NLA3E_11005	COG0778	Nitroreductase
B1NLA3E_11015	COG2720	vancomycin resistance protein
B1NLA3E_11025	COG1368	sulfuric ester hydrolase activity
B1NLA3E_11030	COG1164	Oligoendopeptidase f
B1NLA3E_11035	COG4989	oxidoreductase activity
B1NLA3E_11055	COG2404	hydrolase activity, acting on ester bonds
B1NLA3E_11070	COG1335	isochorismatase
B1NLA3E_11105	COG0697	spore germination
B1NLA3E_11140	COG1104	cysteine desulfurase activity
B1NLA3E_11150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_11190	COG4221	oxidoreductase activity
B1NLA3E_11200	COG1272	protein, Hemolysin III
B1NLA3E_11210	COG0675	Transposase, IS605 OrfB family
B1NLA3E_11220	COG4191	Histidine kinase
B1NLA3E_11255	COG1695	Transcriptional regulator
B1NLA3E_11275	COG0028	Belongs to the TPP enzyme family
B1NLA3E_11285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1NLA3E_11290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B1NLA3E_11295	COG1307	EDD domain protein, DegV family
B1NLA3E_11310	COG1392	Phosphate transport regulator
B1NLA3E_11345	COG0330	HflC and HflK could
B1NLA3E_11360	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1NLA3E_11365	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_11370	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1NLA3E_11375	COG0409	Hydrogenase expression formation protein
B1NLA3E_11380	COG0375	protein maturation
B1NLA3E_11400	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_11405	COG0650	Formate hydrogenlyase subunit 4
B1NLA3E_11410	COG0651	ATP synthesis coupled electron transport
B1NLA3E_11420	COG2414	aldehyde ferredoxin oxidoreductase
B1NLA3E_11425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B1NLA3E_11430	COG2207	Transcriptional regulator
B1NLA3E_11440	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_11445	COG0346	lactoylglutathione lyase activity
B1NLA3E_11465	COG4191	Histidine kinase
B1NLA3E_11475	COG0069	glutamate synthase activity
B1NLA3E_11485	COG2814	Major facilitator Superfamily
B1NLA3E_11490	COG4106	trans-aconitate 2-methyltransferase activity
B1NLA3E_11505	COG4221	oxidoreductase activity
B1NLA3E_11525	COG0653	protein targeting
B1NLA3E_11545	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_11605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B1NLA3E_11655	COG0622	Phosphoesterase
B1NLA3E_11685	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_11695	COG0427	acetyl-CoA hydrolase
B1NLA3E_11710	COG1876	peptidase activity
B1NLA3E_11715	COG0456	acetyltransferase
B1NLA3E_11725	COG0058	SHG alpha-glucan phosphorylase activity
B1NLA3E_11730	COG0297	glycogen (starch) synthase activity
B1NLA3E_11735	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_11740	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_11750	COG0436	Aminotransferase
B1NLA3E_11755	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_11760	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_11765	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_11770	COG0371	Dehydrogenase
B1NLA3E_11775	COG0675	Transposase, IS605 OrfB family
B1NLA3E_11785	COG3300	MHYT domain
B1NLA3E_11785	COG5001	Diguanylate cyclase
B1NLA3E_11795	COG0583	DNA-binding transcription factor activity
B1NLA3E_11810	COG0667	Aldo Keto reductase
B1NLA3E_11820	COG0577	efflux transmembrane transporter activity
B1NLA3E_11825	COG1136	(ABC) transporter
B1NLA3E_11835	COG2205	protein histidine kinase activity
B1NLA3E_11840	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_11855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1NLA3E_11870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1NLA3E_11870	COG1024	Enoyl-CoA hydratase
B1NLA3E_11885	COG2824	Alkylphosphonate utilization operon protein PhnA
B1NLA3E_11890	COG1454	alcohol dehydrogenase
B1NLA3E_11905	COG0248	Ppx GppA phosphatase
B1NLA3E_11910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B1NLA3E_11915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1NLA3E_11925	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_11930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_11950	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_11955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1NLA3E_11960	COG2258	MOSC domain
B1NLA3E_11970	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B1NLA3E_11990	COG3594	Acyltransferase
B1NLA3E_12000	COG2814	Major facilitator Superfamily
B1NLA3E_12010	COG1098	S1 RNA binding domain
B1NLA3E_12020	COG2070	2-Nitropropane dioxygenase
B1NLA3E_12025	COG0247	lactate metabolic process
B1NLA3E_12025	COG2181	nitrate reductase activity
B1NLA3E_12040	COG1113	amino acid transport
B1NLA3E_12070	COG1247	-acetyltransferase
B1NLA3E_12080	COG0077	Prephenate dehydratase
B1NLA3E_12080	COG1605	Chorismate mutase
B1NLA3E_12090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_12115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_12125	COG0577	efflux transmembrane transporter activity
B1NLA3E_12130	COG1136	(ABC) transporter
B1NLA3E_12140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B1NLA3E_12145	COG1876	peptidase activity
B1NLA3E_12150	COG3011	Protein conserved in bacteria
B1NLA3E_12155	COG0656	L-ascorbic acid biosynthetic process
B1NLA3E_12170	COG2323	membrane
B1NLA3E_12175	COG1357	PFAM Pentapeptide repeats (8 copies)
B1NLA3E_12180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B1NLA3E_12200	COG1329	Transcriptional regulator
B1NLA3E_12210	COG0463	Glycosyl transferase, family 2
B1NLA3E_12220	COG0477	Major facilitator Superfamily
B1NLA3E_12235	COG1595	DNA-templated transcription, initiation
B1NLA3E_12240	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_12250	COG4895	conserved protein (DUF2196)
B1NLA3E_12255	COG2848	UPF0210 protein
B1NLA3E_12260	COG3830	Belongs to the UPF0237 family
B1NLA3E_12270	COG4647	ligase activity
B1NLA3E_12275	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
B1NLA3E_12280	COG0145	ligase activity
B1NLA3E_12290	COG4086	secreted protein
B1NLA3E_12295	COG1278	Cold shock
B1NLA3E_12305	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B1NLA3E_12320	COG3341	Caulimovirus viroplasmin
B1NLA3E_12320	COG0328	RNA-DNA hybrid ribonuclease activity
B1NLA3E_12335	COG1279	arginine transmembrane transporter activity
B1NLA3E_12340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_12345	COG2027	D-alanyl-D-alanine carboxypeptidase
B1NLA3E_12355	COG0708	Exodeoxyribonuclease III
B1NLA3E_12360	COG3284	Transcriptional regulator
B1NLA3E_12370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1NLA3E_12375	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1NLA3E_12380	COG0022	dehydrogenase e1 component
B1NLA3E_12385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B1NLA3E_12390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1NLA3E_12390	COG0574	Belongs to the PEP-utilizing enzyme family
B1NLA3E_12395	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B1NLA3E_12400	COG0517	IMP dehydrogenase activity
B1NLA3E_12420	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1NLA3E_12450	COG1657	PFAM Prenyltransferase squalene oxidase
B1NLA3E_12475	COG1587	Uroporphyrinogen-III synthase
B1NLA3E_12485	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B1NLA3E_12490	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_12495	COG0531	amino acid
B1NLA3E_12500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B1NLA3E_12505	COG0157	Belongs to the NadC ModD family
B1NLA3E_12510	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B1NLA3E_12515	COG1104	cysteine desulfurase activity
B1NLA3E_12525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1NLA3E_12530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1NLA3E_12545	COG5337	Spore coat protein CotH
B1NLA3E_12560	COG3773	Cell wall hydrolase
B1NLA3E_12570	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B1NLA3E_12580	COG0535	radical SAM domain protein
B1NLA3E_12595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_12605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1NLA3E_12610	COG2351	hydroxyisourate hydrolase activity
B1NLA3E_12620	COG2080	2 iron, 2 sulfur cluster binding
B1NLA3E_12625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1NLA3E_12630	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B1NLA3E_12635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B1NLA3E_12640	COG0402	S-adenosylhomocysteine deaminase activity
B1NLA3E_12650	COG0133	tryptophan synthase activity
B1NLA3E_12655	COG1418	mRNA catabolic process
B1NLA3E_12665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B1NLA3E_12675	COG0659	secondary active sulfate transmembrane transporter activity
B1NLA3E_12685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_12705	COG0697	spore germination
B1NLA3E_12715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_12720	COG0765	amino acid transport
B1NLA3E_12725	COG1126	abc transporter atp-binding protein
B1NLA3E_12735	COG3383	formate dehydrogenase (NAD+) activity
B1NLA3E_12740	COG0243	molybdopterin cofactor binding
B1NLA3E_12745	COG5002	protein histidine kinase activity
B1NLA3E_12770	COG2814	Major facilitator Superfamily
B1NLA3E_12775	COG1346	cytolysis
B1NLA3E_12780	COG1380	Effector of murein hydrolase LrgA
B1NLA3E_12785	COG1999	signal sequence binding
B1NLA3E_12790	COG0488	(ABC) transporter
B1NLA3E_12805	COG0384	phenazine biosynthesis protein PhzF
B1NLA3E_12815	COG1247	-acetyltransferase
B1NLA3E_12825	COG0456	acetyltransferase
B1NLA3E_12850	COG0725	ABC transporter, periplasmic molybdate-binding protein
B1NLA3E_12855	COG4149	molybdate abc transporter
B1NLA3E_12860	COG1686	Belongs to the peptidase S11 family
B1NLA3E_12875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B1NLA3E_12885	COG0706	membrane insertase activity
B1NLA3E_12900	COG2814	Major facilitator Superfamily
B1NLA3E_12905	COG1846	Transcriptional regulator
B1NLA3E_12910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1NLA3E_12910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1NLA3E_12920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_12925	COG0626	cystathionine gamma-synthase activity
B1NLA3E_12930	COG0626	cystathionine gamma-synthase activity
B1NLA3E_12935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B1NLA3E_12935	COG0646	methionine synthase
B1NLA3E_12940	COG1410	methionine synthase
B1NLA3E_12940	COG0646	methionine synthase
B1NLA3E_12945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B1NLA3E_12955	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
B1NLA3E_12960	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_12990	COG0134	indole-3-glycerol-phosphate synthase activity
B1NLA3E_12995	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B1NLA3E_13000	COG0512	Glutamine amidotransferase of anthranilate synthase
B1NLA3E_13010	COG2814	Major facilitator Superfamily
B1NLA3E_13035	COG1278	Cold shock
B1NLA3E_13040	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_13045	COG1278	Cold shock
B1NLA3E_13050	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B1NLA3E_13055	COG1793	dna ligase
B1NLA3E_13055	COG3285	dna ligase
B1NLA3E_13060	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B1NLA3E_13065	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B1NLA3E_13070	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1NLA3E_13070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1NLA3E_13075	COG0307	riboflavin synthase, alpha
B1NLA3E_13085	COG4667	esterase of the alpha-beta hydrolase superfamily
B1NLA3E_13095	COG1131	(ABC) transporter
B1NLA3E_13115	COG0402	S-adenosylhomocysteine deaminase activity
B1NLA3E_13125	COG0534	Mate efflux family protein
B1NLA3E_13165	COG3409	Peptidoglycan-binding domain 1 protein
B1NLA3E_13165	COG0793	Belongs to the peptidase S41A family
B1NLA3E_13170	COG1876	peptidase activity
B1NLA3E_13185	COG4326	sporulation control protein
B1NLA3E_13200	COG4479	Belongs to the UPF0346 family
B1NLA3E_13205	COG0534	Mate efflux family protein
B1NLA3E_13210	COG4608	Belongs to the ABC transporter superfamily
B1NLA3E_13215	COG0444	Belongs to the ABC transporter superfamily
B1NLA3E_13220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1NLA3E_13225	COG0601	transmembrane transport
B1NLA3E_13230	COG0747	negative chemotaxis
B1NLA3E_13235	COG0456	acetyltransferase
B1NLA3E_13240	COG1846	Transcriptional regulator
B1NLA3E_13245	COG2153	protein acetylation
B1NLA3E_13250	COG2364	Membrane
B1NLA3E_13260	COG0243	molybdopterin cofactor binding
B1NLA3E_13265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_13270	COG2223	nitrite transmembrane transporter activity
B1NLA3E_13275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_13280	COG2146	nitrite reductase [NAD(P)H] activity
B1NLA3E_13285	COG3848	Pyruvate phosphate dikinase
B1NLA3E_13285	COG0574	Belongs to the PEP-utilizing enzyme family
B1NLA3E_13295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1NLA3E_13305	COG1064	alcohol dehydrogenase
B1NLA3E_13310	COG0789	Transcriptional regulator
B1NLA3E_13320	COG0110	maltose O-acetyltransferase activity
B1NLA3E_13330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_13335	COG0477	Major facilitator Superfamily
B1NLA3E_13340	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_13365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1NLA3E_13410	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_13415	COG0789	Transcriptional regulator
B1NLA3E_13420	COG0596	Alpha beta hydrolase
B1NLA3E_13435	COG0456	acetyltransferase
B1NLA3E_13455	COG0488	(ABC) transporter
B1NLA3E_13460	COG0431	NADPH-dependent FMN reductase
B1NLA3E_13465	COG0702	epimerase
B1NLA3E_13480	COG1309	transcriptional regulator
B1NLA3E_13505	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B1NLA3E_13510	COG1247	-acetyltransferase
B1NLA3E_13520	COG2910	NAD(P)H-binding
B1NLA3E_13540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_13545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B1NLA3E_13575	COG1794	racemase activity, acting on amino acids and derivatives
B1NLA3E_13590	COG0456	acetyltransferase
B1NLA3E_13590	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B1NLA3E_13600	COG1268	BioY protein
B1NLA3E_13640	COG3344	reverse transcriptase
B1NLA3E_13660	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_13675	COG1595	DNA-templated transcription, initiation
B1NLA3E_13695	COG2808	Putative FMN-binding domain
B1NLA3E_13725	COG0412	Dienelactone hydrolase
B1NLA3E_13730	COG0697	spore germination
B1NLA3E_13770	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_13775	COG0577	efflux transmembrane transporter activity
B1NLA3E_13780	COG1136	(ABC) transporter
B1NLA3E_13785	COG5002	protein histidine kinase activity
B1NLA3E_13790	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_13800	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_13815	COG1121	(ABC) transporter
B1NLA3E_13825	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_13835	COG5444	nuclease activity
B1NLA3E_13855	COG3706	GGDEF domain
B1NLA3E_13870	COG5001	Diguanylate cyclase
B1NLA3E_13905	COG2207	Transcriptional regulator
B1NLA3E_13910	COG0656	L-ascorbic acid biosynthetic process
B1NLA3E_13915	COG2814	Major facilitator Superfamily
B1NLA3E_13925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1NLA3E_13930	COG0667	Aldo Keto reductase
B1NLA3E_13950	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_14005	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_14010	COG2267	carboxylic ester hydrolase activity
B1NLA3E_14015	COG0583	DNA-binding transcription factor activity
B1NLA3E_14055	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_14060	COG3829	transcription factor binding
B1NLA3E_14065	COG0456	acetyltransferase
B1NLA3E_14070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_14075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1NLA3E_14080	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B1NLA3E_14085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_14090	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1NLA3E_14105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1NLA3E_14110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1NLA3E_14120	COG4698	Protein conserved in bacteria
B1NLA3E_14130	COG1999	signal sequence binding
B1NLA3E_14135	COG1307	EDD domain protein, DegV family
B1NLA3E_14140	COG3764	Sortase (surface protein transpeptidase)
B1NLA3E_14145	COG0309	Hydrogenase expression formation protein (HypE)
B1NLA3E_14150	COG0409	Hydrogenase expression formation protein
B1NLA3E_14155	COG0298	carbon dioxide binding
B1NLA3E_14160	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B1NLA3E_14165	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1NLA3E_14180	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B1NLA3E_14185	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
B1NLA3E_14190	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B1NLA3E_14200	COG0805	protein transport
B1NLA3E_14205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_14210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1NLA3E_14220	COG1272	protein, Hemolysin III
B1NLA3E_14225	COG0204	Acyl-transferase
B1NLA3E_14230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B1NLA3E_14235	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B1NLA3E_14240	COG2310	stress, protein
B1NLA3E_14245	COG3853	Toxic anion resistance protein (TelA)
B1NLA3E_14275	COG0861	Integral membrane protein TerC family
B1NLA3E_14280	COG2310	stress, protein
B1NLA3E_14290	COG0436	Aminotransferase
B1NLA3E_14300	COG1819	glycosyl
B1NLA3E_14355	COG1413	lyase activity
B1NLA3E_14360	COG0488	(ABC) transporter
B1NLA3E_14365	COG1418	mRNA catabolic process
B1NLA3E_14380	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B1NLA3E_14385	COG2226	methyltransferase
B1NLA3E_14390	COG1321	iron dependent repressor
B1NLA3E_14400	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B1NLA3E_14405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B1NLA3E_14420	COG1278	Cold shock
B1NLA3E_14430	COG0328	RNA-DNA hybrid ribonuclease activity
B1NLA3E_14435	COG0328	RNA-DNA hybrid ribonuclease activity
B1NLA3E_14450	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B1NLA3E_14460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1NLA3E_14470	COG1924	4 iron, 4 sulfur cluster binding
B1NLA3E_14475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B1NLA3E_14480	COG1755	Isoprenylcysteine carboxyl methyltransferase
B1NLA3E_14485	COG3424	synthase
B1NLA3E_14500	COG2233	PERMEase
B1NLA3E_14505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1NLA3E_14510	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B1NLA3E_14515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1NLA3E_14520	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B1NLA3E_14535	COG1199	ATP-dependent helicase activity
B1NLA3E_14540	COG0116	Belongs to the methyltransferase superfamily
B1NLA3E_14545	COG3599	regulation of cell shape
B1NLA3E_14550	COG4474	Belongs to the UPF0398 family
B1NLA3E_14560	COG3359	exonuclease
B1NLA3E_14565	COG1111	helicase
B1NLA3E_14565	COG1205	dead DEAH box helicase
B1NLA3E_14575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_14580	COG1151	hydroxylamine reductase activity
B1NLA3E_14590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1NLA3E_14625	COG4499	WXG100 protein secretion system (Wss), protein YukC
B1NLA3E_14625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1NLA3E_14635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B1NLA3E_14640	COG3935	DnaD domain protein
B1NLA3E_14645	COG0017	Asparaginyl-tRNA synthetase
B1NLA3E_14660	COG1199	ATP-dependent helicase activity
B1NLA3E_14660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1NLA3E_14665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B1NLA3E_14670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B1NLA3E_14680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B1NLA3E_14680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B1NLA3E_14685	COG0617	tRNA 3'-terminal CCA addition
B1NLA3E_14690	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_14695	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1NLA3E_14700	COG1803	Methylglyoxal synthase
B1NLA3E_14705	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B1NLA3E_14710	COG1694	Mazg nucleotide pyrophosphohydrolase
B1NLA3E_14715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_14720	COG2738	Putative neutral zinc metallopeptidase
B1NLA3E_14730	COG4347	Protein of unknown function (DUF1405)
B1NLA3E_14735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1NLA3E_14735	COG2010	Cytochrome c
B1NLA3E_14740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1NLA3E_14755	COG5582	Belongs to the UPF0302 family
B1NLA3E_14760	COG0457	Tetratricopeptide repeat
B1NLA3E_14770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B1NLA3E_14775	COG0287	Prephenate dehydrogenase
B1NLA3E_14780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1NLA3E_14785	COG4401	Chorismate mutase type I
B1NLA3E_14790	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1NLA3E_14795	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B1NLA3E_14800	COG0105	UTP biosynthetic process
B1NLA3E_14805	COG0142	geranyltranstransferase activity
B1NLA3E_14810	COG2226	methyltransferase
B1NLA3E_14815	COG0142	geranyltranstransferase activity
B1NLA3E_14825	COG0776	regulation of translation
B1NLA3E_14830	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B1NLA3E_14850	COG1160	GTP binding
B1NLA3E_14875	COG1304	FMN binding
B1NLA3E_14880	COG0539	negative regulation of cytoplasmic translation
B1NLA3E_14900	COG2959	enzyme of heme biosynthesis
B1NLA3E_14905	COG3773	Cell wall hydrolase
B1NLA3E_14905	COG3409	Peptidoglycan-binding domain 1 protein
B1NLA3E_14910	COG2339	peptidase activity
B1NLA3E_14915	COG0492	ferredoxin-NADP+ reductase activity
B1NLA3E_14920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1NLA3E_14925	COG4862	establishment of competence for transformation
B1NLA3E_14930	COG1408	metallophosphoesterase
B1NLA3E_14950	COG3546	catalase activity
B1NLA3E_14960	COG1388	LysM domain
B1NLA3E_14960	COG1705	Flagellar rod assembly protein muramidase FlgJ
B1NLA3E_14965	COG1266	CAAX protease self-immunity
B1NLA3E_14970	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_14975	COG4955	Helix-turn-helix domain
B1NLA3E_14985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1NLA3E_14990	COG0739	heme binding
B1NLA3E_15005	COG1595	DNA-templated transcription, initiation
B1NLA3E_15010	COG5002	protein histidine kinase activity
B1NLA3E_15015	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_15020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1NLA3E_15025	COG1333	cytochrome c biogenesis protein
B1NLA3E_15030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_15035	COG1187	pseudouridine synthase activity
B1NLA3E_15040	COG0700	Nucleoside recognition
B1NLA3E_15045	COG2715	membrane protein required for spore maturation
B1NLA3E_15050	COG1686	Belongs to the peptidase S11 family
B1NLA3E_15060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B1NLA3E_15075	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B1NLA3E_15080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B1NLA3E_15085	COG1547	Domain of unknown function (DUF309)
B1NLA3E_15095	COG0531	amino acid
B1NLA3E_15105	COG0697	spore germination
B1NLA3E_15125	COG1191	sigma factor activity
B1NLA3E_15130	COG2172	sigma factor antagonist activity
B1NLA3E_15140	COG1686	Belongs to the peptidase S11 family
B1NLA3E_15165	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_15175	COG0735	belongs to the Fur family
B1NLA3E_15180	COG1300	Membrane
B1NLA3E_15185	COG1379	DNA repair
B1NLA3E_15200	COG0667	Aldo Keto reductase
B1NLA3E_15210	COG1073	alpha beta
B1NLA3E_15225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B1NLA3E_15230	COG1476	TRANSCRIPTIONal
B1NLA3E_15245	COG0300	oxidoreductase activity
B1NLA3E_15250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_15255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1NLA3E_15260	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_15270	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B1NLA3E_15275	COG0583	DNA-binding transcription factor activity
B1NLA3E_15285	COG0778	Nitroreductase
B1NLA3E_15295	COG1234	tRNA 3'-trailer cleavage
B1NLA3E_15300	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B1NLA3E_15305	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B1NLA3E_15310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B1NLA3E_15315	COG2195	Cleaves the N-terminal amino acid of tripeptides
B1NLA3E_15320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1NLA3E_15325	COG0346	lactoylglutathione lyase activity
B1NLA3E_15330	COG1376	ErfK ybiS ycfS ynhG family protein
B1NLA3E_15335	COG4129	membrane
B1NLA3E_15350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_15350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_15365	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1NLA3E_15370	COG0022	dehydrogenase e1 component
B1NLA3E_15375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B1NLA3E_15380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1NLA3E_15395	COG3290	protein histidine kinase activity
B1NLA3E_15395	COG3829	transcription factor binding
B1NLA3E_15405	COG0584	glycerophosphoryl diester phosphodiesterase
B1NLA3E_15410	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_15415	COG0750	zinc metalloprotease
B1NLA3E_15420	COG0497	DNA recombination
B1NLA3E_15430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B1NLA3E_15435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1NLA3E_15445	COG1722	exodeoxyribonuclease VII activity
B1NLA3E_15455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B1NLA3E_15465	COG1302	Protein conserved in bacteria
B1NLA3E_15470	COG0439	Biotin carboxylase
B1NLA3E_15475	COG0511	ligase activity, forming carbon-carbon bonds
B1NLA3E_15515	COG3854	ATPases associated with a variety of cellular activities
B1NLA3E_15530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1NLA3E_15540	COG4555	ABC transporter
B1NLA3E_15560	COG1138	Cytochrome C-type biogenesis protein
B1NLA3E_15575	COG2010	Cytochrome c
B1NLA3E_15580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B1NLA3E_15585	COG0006	proline dipeptidase activity
B1NLA3E_15595	COG3872	metal-dependent enzyme
B1NLA3E_15605	COG1752	Esterase of the alpha-beta hydrolase superfamily
B1NLA3E_15615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B1NLA3E_15620	COG0095	Lipoate-protein ligase
B1NLA3E_15625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_15635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1NLA3E_15640	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1NLA3E_15645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1NLA3E_15650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1NLA3E_15685	COG4537	Required for transformation and DNA binding
B1NLA3E_15690	COG1459	type II secretion system
B1NLA3E_15695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B1NLA3E_15705	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B1NLA3E_15800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_15805	COG0675	Transposase, IS605 OrfB family
B1NLA3E_15830	COG1368	sulfuric ester hydrolase activity
B1NLA3E_15835	COG1940	carbohydrate kinase activity
B1NLA3E_15845	COG0697	spore germination
B1NLA3E_15860	COG0705	Rhomboid family
B1NLA3E_15860	COG0457	Tetratricopeptide repeat
B1NLA3E_15880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B1NLA3E_15885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1NLA3E_15905	COG0704	Plays a role in the regulation of phosphate uptake
B1NLA3E_15920	COG0573	inorganic phosphate transmembrane transporter activity
B1NLA3E_15925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B1NLA3E_15935	COG0477	Major facilitator Superfamily
B1NLA3E_15945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_15950	COG2839	Protein conserved in bacteria
B1NLA3E_15955	COG5521	maltodextrose utilization protein MalA
B1NLA3E_15965	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B1NLA3E_15970	COG4709	membrane
B1NLA3E_15975	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
B1NLA3E_15980	COG0735	belongs to the Fur family
B1NLA3E_15985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B1NLA3E_15990	COG1121	(ABC) transporter
B1NLA3E_16000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B1NLA3E_16005	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_16015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B1NLA3E_16020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B1NLA3E_16025	COG2384	SAM-dependent methyltransferase
B1NLA3E_16030	COG2010	Cytochrome c
B1NLA3E_16035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1NLA3E_16040	COG0358	DNA primase activity
B1NLA3E_16045	COG1671	Belongs to the UPF0178 family
B1NLA3E_16050	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B1NLA3E_16055	COG0517	IMP dehydrogenase activity
B1NLA3E_16060	COG0423	glycine-tRNA ligase activity
B1NLA3E_16065	COG1381	Involved in DNA repair and RecF pathway recombination
B1NLA3E_16075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B1NLA3E_16080	COG0295	cytidine deaminase activity
B1NLA3E_16085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B1NLA3E_16090	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B1NLA3E_16095	COG1480	7TM receptor with intracellular HD hydrolase
B1NLA3E_16100	COG1702	phosphate starvation-inducible protein PhoH
B1NLA3E_16115	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B1NLA3E_16125	COG4864	UPF0365 protein
B1NLA3E_16130	COG1030	water channel activity
B1NLA3E_16135	COG1610	YqeY-like protein
B1NLA3E_16140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B1NLA3E_16145	COG1283	sodium-dependent phosphate transmembrane transporter activity
B1NLA3E_16150	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B1NLA3E_16160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1NLA3E_16165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B1NLA3E_16170	COG2264	protein methyltransferase activity
B1NLA3E_16180	COG0443	Heat shock 70 kDa protein
B1NLA3E_16185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B1NLA3E_16195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B1NLA3E_16200	COG0481	GTPase activity
B1NLA3E_16210	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_16220	COG0268	Binds directly to 16S ribosomal RNA
B1NLA3E_16225	COG1466	dna polymerase III delta subunit
B1NLA3E_16235	COG0658	competence protein
B1NLA3E_16235	COG2333	competence protein COMEC
B1NLA3E_16240	COG2131	deaminase
B1NLA3E_16245	COG1555	photosystem II stabilization
B1NLA3E_16245	COG1596	polysaccharide export
B1NLA3E_16250	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1NLA3E_16255	COG2226	methyltransferase
B1NLA3E_16260	COG0799	negative regulation of ribosome biogenesis
B1NLA3E_16265	COG1713	HD superfamily hydrolase involved in NAD metabolism
B1NLA3E_16270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B1NLA3E_16275	COG1534	Rna-binding protein
B1NLA3E_16285	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B1NLA3E_16290	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B1NLA3E_16300	COG0688	phosphatidylethanolamine metabolic process
B1NLA3E_16305	COG1183	phosphatidylcholine synthase activity
B1NLA3E_16320	COG0626	cystathionine gamma-synthase activity
B1NLA3E_16325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_16330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B1NLA3E_16335	COG2226	methyltransferase
B1NLA3E_16345	COG0768	penicillin binding
B1NLA3E_16350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1NLA3E_16355	COG0572	uridine kinase
B1NLA3E_16375	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B1NLA3E_16380	COG3906	Belongs to the UPF0473 family
B1NLA3E_16400	COG0628	permease
B1NLA3E_16435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B1NLA3E_16450	COG1104	cysteine desulfurase activity
B1NLA3E_16455	COG1959	2 iron, 2 sulfur cluster binding
B1NLA3E_16460	COG2364	Membrane
B1NLA3E_16465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B1NLA3E_16470	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B1NLA3E_16475	COG1131	(ABC) transporter
B1NLA3E_16480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B1NLA3E_16485	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B1NLA3E_16490	COG0124	histidyl-tRNA synthetase
B1NLA3E_16500	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_16500	COG3103	Sh3 type 3 domain protein
B1NLA3E_16500	COG4991	sh3 domain protein
B1NLA3E_16505	COG1490	D-aminoacyl-tRNA deacylase activity
B1NLA3E_16510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1NLA3E_16515	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1NLA3E_16520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B1NLA3E_16520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B1NLA3E_16525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1NLA3E_16525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1NLA3E_16535	COG2244	polysaccharide biosynthetic process
B1NLA3E_16540	COG2323	membrane
B1NLA3E_16550	COG1862	Preprotein translocase
B1NLA3E_16560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B1NLA3E_16590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B1NLA3E_16600	COG1388	LysM domain
B1NLA3E_16605	COG1827	regulation of RNA biosynthetic process
B1NLA3E_16610	COG0077	Prephenate dehydratase
B1NLA3E_16615	COG4492	Belongs to the UPF0735 family
B1NLA3E_16620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B1NLA3E_16625	COG3290	protein histidine kinase activity
B1NLA3E_16635	COG2868	ribosomal protein
B1NLA3E_16645	COG1530	ribonuclease E activity
B1NLA3E_16650	COG1994	Peptidase M50
B1NLA3E_16655	COG0739	heme binding
B1NLA3E_16660	COG2894	cell division
B1NLA3E_16670	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B1NLA3E_16675	COG1792	Involved in formation and maintenance of cell shape
B1NLA3E_16680	COG1077	Cell shape determining protein MreB Mrl
B1NLA3E_16685	COG2003	Belongs to the UPF0758 family
B1NLA3E_16715	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B1NLA3E_16765	COG0285	dihydrofolate synthase activity
B1NLA3E_16770	COG0525	valine-tRNA ligase activity
B1NLA3E_16780	COG1388	LysM domain
B1NLA3E_16790	COG0113	porphobilinogen synthase activity
B1NLA3E_16800	COG0181	hydroxymethylbilane synthase activity
B1NLA3E_16805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1NLA3E_16825	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B1NLA3E_16830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B1NLA3E_16835	COG0470	DNA polymerase III
B1NLA3E_16835	COG1067	ATP-dependent peptidase activity
B1NLA3E_16840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B1NLA3E_16845	COG0544	peptidyl-prolyl cis-trans isomerase activity
B1NLA3E_16850	COG1477	protein flavinylation
B1NLA3E_16850	COG0457	Tetratricopeptide repeat
B1NLA3E_16855	COG0066	3-isopropylmalate dehydratase activity
B1NLA3E_16860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B1NLA3E_16865	COG0473	3-isopropylmalate dehydrogenase activity
B1NLA3E_16870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1NLA3E_16875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B1NLA3E_16880	COG0440	acetolactate synthase activity
B1NLA3E_16885	COG0028	Belongs to the TPP enzyme family
B1NLA3E_16900	COG0622	Phosphoesterase
B1NLA3E_16910	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B1NLA3E_16915	COG5401	PFAM Sporulation and spore germination
B1NLA3E_16925	COG1846	Transcriptional regulator
B1NLA3E_16930	COG2197	response regulator
B1NLA3E_16935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1NLA3E_16940	COG1053	succinate dehydrogenase
B1NLA3E_16945	COG2009	succinate dehydrogenase
B1NLA3E_16965	COG0322	excinuclease ABC activity
B1NLA3E_16970	COG3118	belongs to the thioredoxin family
B1NLA3E_16975	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_16980	COG2086	electron transfer activity
B1NLA3E_16985	COG1024	Enoyl-CoA hydratase
B1NLA3E_16990	COG1309	transcriptional regulator
B1NLA3E_17005	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_17010	COG3766	membrane
B1NLA3E_17020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1NLA3E_17020	COG1796	DNA polymerase
B1NLA3E_17025	COG1286	toxin biosynthetic process
B1NLA3E_17030	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B1NLA3E_17035	COG0072	phenylalanine-tRNA ligase activity
B1NLA3E_17035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1NLA3E_17040	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B1NLA3E_17045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1NLA3E_17055	COG1363	Peptidase, m42
B1NLA3E_17065	COG3326	Membrane
B1NLA3E_17070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B1NLA3E_17080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B1NLA3E_17085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B1NLA3E_17095	COG1484	DNA-dependent DNA replication
B1NLA3E_17100	COG3611	Membrane attachment protein
B1NLA3E_17105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B1NLA3E_17110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B1NLA3E_17115	COG0237	dephospho-CoA kinase activity
B1NLA3E_17120	COG1971	Probably functions as a manganese efflux pump
B1NLA3E_17125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1NLA3E_17130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1NLA3E_17130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1NLA3E_17135	COG5002	protein histidine kinase activity
B1NLA3E_17140	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_17145	COG0039	L-malate dehydrogenase activity
B1NLA3E_17150	COG0538	isocitrate dehydrogenase activity
B1NLA3E_17155	COG0372	Belongs to the citrate synthase family
B1NLA3E_17160	COG2707	UPF0756 membrane protein
B1NLA3E_17165	COG0628	permease
B1NLA3E_17170	COG3030	protein affecting phage T7 exclusion by the F plasmid
B1NLA3E_17180	COG0205	6-phosphofructokinase activity
B1NLA3E_17185	COG0825	malonyl-CoA metabolic process
B1NLA3E_17190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B1NLA3E_17195	COG2186	Transcriptional regulator
B1NLA3E_17200	COG0281	malic enzyme
B1NLA3E_17205	COG0587	DNA-directed DNA polymerase activity
B1NLA3E_17220	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B1NLA3E_17230	COG4109	DRTGG domain
B1NLA3E_17235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B1NLA3E_17240	COG0006	proline dipeptidase activity
B1NLA3E_17250	COG0589	response to stress
B1NLA3E_17255	COG0165	Argininosuccinate lyase
B1NLA3E_17260	COG0137	argininosuccinate synthase activity
B1NLA3E_17270	COG0521	Mo-molybdopterin cofactor biosynthetic process
B1NLA3E_17280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B1NLA3E_17285	COG0827	DNA restriction-modification system
B1NLA3E_17290	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B1NLA3E_17295	COG3874	Sporulation protein YtfJ
B1NLA3E_17305	COG1714	RDD family
B1NLA3E_17310	COG0616	signal peptide processing
B1NLA3E_17315	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B1NLA3E_17330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1NLA3E_17345	COG1104	cysteine desulfurase activity
B1NLA3E_17350	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B1NLA3E_17355	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1NLA3E_17360	COG1309	transcriptional regulator
B1NLA3E_17390	COG2203	Gaf domain
B1NLA3E_17390	COG2199	diguanylate cyclase activity
B1NLA3E_17395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B1NLA3E_17400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B1NLA3E_17410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1NLA3E_17415	COG0454	-acetyltransferase
B1NLA3E_17420	COG0517	IMP dehydrogenase activity
B1NLA3E_17425	COG0123	including yeast histone deacetylase and acetoin utilization protein
B1NLA3E_17435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B1NLA3E_17435	COG1605	Chorismate mutase
B1NLA3E_17440	COG3118	belongs to the thioredoxin family
B1NLA3E_17445	COG4980	gas vesicle protein
B1NLA3E_17450	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B1NLA3E_17455	COG2309	aminopeptidase activity
B1NLA3E_17460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B1NLA3E_17465	COG1674	ftsk spoiiie
B1NLA3E_17470	COG4848	Belongs to the UPF0354 family
B1NLA3E_17475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_17485	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
B1NLA3E_17490	COG1363	Peptidase, m42
B1NLA3E_17495	COG5584	Small secreted protein
B1NLA3E_17500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B1NLA3E_17510	COG0510	thiamine kinase activity
B1NLA3E_17515	COG1523	belongs to the glycosyl hydrolase 13 family
B1NLA3E_17520	COG1597	lipid kinase activity
B1NLA3E_17530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_17540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_17545	COG1349	DNA-binding transcription factor activity
B1NLA3E_17550	COG1187	pseudouridine synthase activity
B1NLA3E_17560	COG2244	polysaccharide biosynthetic process
B1NLA3E_17565	COG2081	HI0933 family
B1NLA3E_17585	COG1309	transcriptional regulator
B1NLA3E_17590	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_17590	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1NLA3E_17605	COG4221	oxidoreductase activity
B1NLA3E_17610	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_17615	COG0789	Transcriptional regulator
B1NLA3E_17620	COG1733	regulation of RNA biosynthetic process
B1NLA3E_17625	COG2085	NADP oxidoreductase coenzyme F420-dependent
B1NLA3E_17650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_17655	COG0495	leucyl-tRNA aminoacylation
B1NLA3E_17660	COG2814	Major facilitator Superfamily
B1NLA3E_17665	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B1NLA3E_17675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_17690	COG1138	Cytochrome C-type biogenesis protein
B1NLA3E_17710	COG1242	4 iron, 4 sulfur cluster binding
B1NLA3E_17715	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B1NLA3E_17725	COG2267	carboxylic ester hydrolase activity
B1NLA3E_17730	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B1NLA3E_17735	COG0367	asparagine synthase
B1NLA3E_17740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B1NLA3E_17755	COG1506	peptidase
B1NLA3E_17760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_17765	COG1116	anion transmembrane transporter activity
B1NLA3E_17770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_17780	COG0494	nUDIX hydrolase
B1NLA3E_17795	COG0783	Belongs to the Dps family
B1NLA3E_17805	COG1854	S-ribosylhomocysteine lyase activity
B1NLA3E_17810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B1NLA3E_17815	COG0288	reversible hydration of carbon dioxide
B1NLA3E_17820	COG0803	Belongs to the bacterial solute-binding protein 9 family
B1NLA3E_17830	COG4948	Mandelate Racemase Muconate Lactonizing
B1NLA3E_17840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B1NLA3E_17845	COG0596	Alpha beta hydrolase
B1NLA3E_17850	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B1NLA3E_17855	COG1169	isochorismate synthase
B1NLA3E_17865	COG1575	Belongs to the MenA family. Type 1 subfamily
B1NLA3E_17870	COG0058	SHG alpha-glucan phosphorylase activity
B1NLA3E_17875	COG0297	glycogen (starch) synthase activity
B1NLA3E_17880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_17885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_17905	COG1285	pathogenesis
B1NLA3E_17910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1NLA3E_17920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_17930	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_17940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_17945	COG2368	4-hydroxyphenylacetate
B1NLA3E_17950	COG2368	4-hydroxyphenylacetate
B1NLA3E_17955	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_17965	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_17980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1NLA3E_17985	COG0789	Transcriptional regulator
B1NLA3E_17990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B1NLA3E_17995	COG0671	phosphoesterase, PA-phosphatase related
B1NLA3E_18000	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_18005	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_18030	COG2814	Major facilitator Superfamily
B1NLA3E_18035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B1NLA3E_18050	COG2197	response regulator
B1NLA3E_18055	COG1191	sigma factor activity
B1NLA3E_18065	COG0455	bacterial-type flagellum organization
B1NLA3E_18070	COG1419	protein localization to endoplasmic reticulum
B1NLA3E_18075	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B1NLA3E_18080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B1NLA3E_18085	COG1684	flagellar biosynthetic protein fliR
B1NLA3E_18090	COG1987	bacterial-type flagellum assembly
B1NLA3E_18095	COG1338	Plays a role in the flagellum-specific transport system
B1NLA3E_18100	COG3190	flagellar
B1NLA3E_18115	COG1157	protein secretion by the type III secretion system
B1NLA3E_18125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1NLA3E_18130	COG1766	The M ring may be actively involved in energy transduction
B1NLA3E_18135	COG1677	Flagellar hook-basal body complex protein FliE
B1NLA3E_18140	COG1558	bacterial-type flagellum-dependent cell motility
B1NLA3E_18145	COG1815	bacterial-type flagellum-dependent cell motility
B1NLA3E_18165	COG1516	flagellar protein fliS
B1NLA3E_18180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B1NLA3E_18185	COG1256	bacterial-type flagellum assembly
B1NLA3E_18185	COG4786	Flagellar basal body rod
B1NLA3E_18205	COG1334	flagellar protein FlaG
B1NLA3E_18215	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B1NLA3E_18220	COG4786	Flagellar basal body rod
B1NLA3E_18225	COG4786	Flagellar basal body rod
B1NLA3E_18235	COG1728	Protein conserved in bacteria
B1NLA3E_18245	COG0835	chemotaxis
B1NLA3E_18250	COG0835	chemotaxis
B1NLA3E_18255	COG2198	Histidine kinase
B1NLA3E_18255	COG0643	Histidine kinase
B1NLA3E_18260	COG2201	protein-glutamate methylesterase activity
B1NLA3E_18265	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1NLA3E_18265	COG1776	CheC inhibitor of MCP methylation
B1NLA3E_18270	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1NLA3E_18275	COG4786	Flagellar basal body rod
B1NLA3E_18280	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B1NLA3E_18290	COG2201	protein-glutamate methylesterase activity
B1NLA3E_18295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B1NLA3E_18300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B1NLA3E_18320	COG1396	sequence-specific DNA binding
B1NLA3E_18325	COG0730	response to heat
B1NLA3E_18330	COG0753	catalase activity
B1NLA3E_18335	COG0385	Bile acid
B1NLA3E_18340	COG0783	Belongs to the Dps family
B1NLA3E_18345	COG0492	ferredoxin-NADP+ reductase activity
B1NLA3E_18355	COG3773	Cell wall hydrolase
B1NLA3E_18360	COG2814	Major facilitator Superfamily
B1NLA3E_18370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1NLA3E_18380	COG0697	spore germination
B1NLA3E_18385	COG0352	thiamine-phosphate diphosphorylase activity
B1NLA3E_18390	COG0351	phosphomethylpyrimidine kinase
B1NLA3E_18395	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B1NLA3E_18415	COG0205	6-phosphofructokinase activity
B1NLA3E_18425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1NLA3E_18430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1NLA3E_18435	COG0698	ribose 5-phosphate isomerase
B1NLA3E_18445	COG1063	alcohol dehydrogenase
B1NLA3E_18450	COG3775	system Galactitol-specific IIC component
B1NLA3E_18455	COG3414	Phosphotransferase system galactitol-specific IIB component
B1NLA3E_18460	COG3414	Phosphotransferase system galactitol-specific IIB component
B1NLA3E_18480	COG0004	ammonium transporteR
B1NLA3E_18490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B1NLA3E_18505	COG1979	alcohol dehydrogenase
B1NLA3E_18510	COG2155	Conserved Protein
B1NLA3E_18515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1NLA3E_18520	COG1098	S1 RNA binding domain
B1NLA3E_18530	COG0436	Aminotransferase
B1NLA3E_18535	COG1522	sequence-specific DNA binding
B1NLA3E_18540	COG2267	carboxylic ester hydrolase activity
B1NLA3E_18545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B1NLA3E_18550	COG2032	superoxide dismutase activity
B1NLA3E_18560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B1NLA3E_18570	COG5018	Exonuclease
B1NLA3E_18575	COG2050	protein possibly involved in aromatic compounds catabolism
B1NLA3E_18580	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_18585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B1NLA3E_18590	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B1NLA3E_18595	COG3584	3D domain protein
B1NLA3E_18605	COG1252	NADH dehydrogenase
B1NLA3E_18615	COG1196	nuclear chromosome segregation
B1NLA3E_18615	COG0741	lytic transglycosylase activity
B1NLA3E_18615	COG0739	heme binding
B1NLA3E_18630	COG0316	Belongs to the HesB IscA family
B1NLA3E_18640	COG1252	NADH dehydrogenase
B1NLA3E_18645	COG4837	Protein of unknown function (DUF1462)
B1NLA3E_18650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B1NLA3E_18655	COG0083	homoserine kinase activity
B1NLA3E_18660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B1NLA3E_18665	COG0460	homoserine dehydrogenase
B1NLA3E_18670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1NLA3E_18675	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B1NLA3E_18680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B1NLA3E_18685	COG0647	UMP catabolic process
B1NLA3E_18690	COG2445	Protein of unknown function DUF86
B1NLA3E_18700	COG4470	Protein conserved in bacteria
B1NLA3E_18710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B1NLA3E_18715	COG0739	heme binding
B1NLA3E_18725	COG3377	Domain of unknown function (DUF1805)
B1NLA3E_18730	COG0737	Belongs to the 5'-nucleotidase family
B1NLA3E_18735	COG0719	Fe-S assembly protein
B1NLA3E_18740	COG0822	iron-sulfur transferase activity
B1NLA3E_18745	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1NLA3E_18750	COG0719	Fe-S assembly protein
B1NLA3E_18755	COG0396	ATPase activity
B1NLA3E_18760	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_18765	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_18770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_18790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_18795	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B1NLA3E_18800	COG0509	glycine decarboxylation via glycine cleavage system
B1NLA3E_18805	COG1393	Belongs to the ArsC family
B1NLA3E_18810	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_18815	COG0183	Belongs to the thiolase family
B1NLA3E_18820	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1NLA3E_18820	COG1024	Enoyl-CoA hydratase
B1NLA3E_18830	COG0506	proline dehydrogenase activity
B1NLA3E_18840	COG1120	ATPase activity
B1NLA3E_18845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1NLA3E_18850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1NLA3E_18855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B1NLA3E_18875	COG0772	Belongs to the SEDS family
B1NLA3E_18885	COG1910	domain protein
B1NLA3E_18895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B1NLA3E_18905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1NLA3E_18910	COG0673	inositol 2-dehydrogenase activity
B1NLA3E_18920	COG2112	serine threonine protein kinase
B1NLA3E_18925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B1NLA3E_18940	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1NLA3E_18950	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1NLA3E_18960	COG0004	ammonium transporteR
B1NLA3E_18980	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_19005	COG2706	6-phosphogluconolactonase activity
B1NLA3E_19010	COG0392	lysyltransferase activity
B1NLA3E_19010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B1NLA3E_19015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1NLA3E_19020	COG4990	cell redox homeostasis
B1NLA3E_19025	COG4990	cell redox homeostasis
B1NLA3E_19045	COG0071	Belongs to the small heat shock protein (HSP20) family
B1NLA3E_19060	COG4221	oxidoreductase activity
B1NLA3E_19065	COG5002	protein histidine kinase activity
B1NLA3E_19070	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_19075	COG1132	(ABC) transporter
B1NLA3E_19085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_19090	COG0196	riboflavin kinase activity
B1NLA3E_19100	COG3300	MHYT domain
B1NLA3E_19100	COG5001	Diguanylate cyclase
B1NLA3E_19105	COG0805	protein transport
B1NLA3E_19115	COG4149	molybdate abc transporter
B1NLA3E_19120	COG0725	ABC transporter, periplasmic molybdate-binding protein
B1NLA3E_19130	COG0314	molybdopterin synthase activity
B1NLA3E_19135	COG1763	Mo-molybdopterin cofactor biosynthetic process
B1NLA3E_19140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1NLA3E_19145	COG0303	'Molybdopterin
B1NLA3E_19150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_19155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_19160	COG3302	dmso reductase anchor subunit
B1NLA3E_19165	COG0437	4 iron, 4 sulfur cluster binding
B1NLA3E_19170	COG0243	molybdopterin cofactor binding
B1NLA3E_19175	COG2964	Protein conserved in bacteria
B1NLA3E_19180	COG0251	oxidation-reduction process
B1NLA3E_19185	COG0626	cystathionine gamma-synthase activity
B1NLA3E_19190	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B1NLA3E_19195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B1NLA3E_19200	COG0833	amino acid
B1NLA3E_19205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_19230	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B1NLA3E_19235	COG0557	exoribonuclease II activity
B1NLA3E_19240	COG1647	Serine aminopeptidase, S33
B1NLA3E_19245	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1NLA3E_19290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1NLA3E_19300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_19305	COG1481	regulation of sporulation
B1NLA3E_19310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B1NLA3E_19315	COG1660	Displays ATPase and GTPase activities
B1NLA3E_19320	COG1051	belongs to the nudix hydrolase family
B1NLA3E_19325	COG0492	ferredoxin-NADP+ reductase activity
B1NLA3E_19330	COG0457	Tetratricopeptide repeat
B1NLA3E_19335	COG0140	phosphoribosyl-ATP diphosphatase activity
B1NLA3E_19335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B1NLA3E_19340	COG0107	imidazoleglycerol-phosphate synthase activity
B1NLA3E_19345	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B1NLA3E_19350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B1NLA3E_19355	COG0131	Imidazoleglycerol-phosphate dehydratase
B1NLA3E_19360	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B1NLA3E_19365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B1NLA3E_19370	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B1NLA3E_19375	COG0110	maltose O-acetyltransferase activity
B1NLA3E_19385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B1NLA3E_19390	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B1NLA3E_19400	COG1950	PFAM Membrane protein of
B1NLA3E_19410	COG3595	metallopeptidase activity
B1NLA3E_19420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1NLA3E_19440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1NLA3E_19445	COG1309	transcriptional regulator
B1NLA3E_19450	COG4549	nuclear export factor GLE1
B1NLA3E_19475	COG2217	Heavy metal translocating P-type atpase
B1NLA3E_19480	COG2608	mercury ion transmembrane transporter activity
B1NLA3E_19505	COG2132	Multicopper oxidase
B1NLA3E_19525	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_19530	COG5002	protein histidine kinase activity
B1NLA3E_19545	COG5002	protein histidine kinase activity
B1NLA3E_19555	COG2217	Heavy metal translocating P-type atpase
B1NLA3E_19580	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B1NLA3E_19590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_19600	COG3850	Histidine kinase
B1NLA3E_19600	COG5002	protein histidine kinase activity
B1NLA3E_19605	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_19610	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_19630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_19635	COG0793	Belongs to the peptidase S41A family
B1NLA3E_19635	COG3409	Peptidoglycan-binding domain 1 protein
B1NLA3E_19640	COG1968	undecaprenyl-diphosphatase activity
B1NLA3E_19650	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B1NLA3E_19655	COG0791	NLP P60 protein
B1NLA3E_19655	COG3883	PFAM NLP P60 protein
B1NLA3E_19660	COG2177	Part of the ABC transporter FtsEX involved in
B1NLA3E_19665	COG2884	Cell division ATP-binding protein ftsE
B1NLA3E_19675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_19680	COG1253	flavin adenine dinucleotide binding
B1NLA3E_19685	COG2738	Putative neutral zinc metallopeptidase
B1NLA3E_19690	COG0861	Integral membrane protein TerC family
B1NLA3E_19740	COG0653	protein targeting
B1NLA3E_19745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B1NLA3E_19750	COG2059	Chromate
B1NLA3E_19755	COG2059	Chromate
B1NLA3E_19770	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B1NLA3E_19775	COG4193	domain, Protein
B1NLA3E_19785	COG1307	EDD domain protein, DegV family
B1NLA3E_19895	COG2197	response regulator
B1NLA3E_19900	COG1739	Uncharacterized protein family UPF0029
B1NLA3E_19905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1NLA3E_19910	COG1091	dTDP-4-dehydrorhamnose reductase activity
B1NLA3E_19925	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B1NLA3E_19950	COG4166	transmembrane transport
B1NLA3E_19955	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_19965	COG1442	glycosyl transferase family 8
B1NLA3E_19965	COG1216	Glycosyl transferase, family 2
B1NLA3E_19975	COG2244	polysaccharide biosynthetic process
B1NLA3E_19980	COG1316	TRANSCRIPTIONal
B1NLA3E_19995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_20035	COG1484	DNA-dependent DNA replication
B1NLA3E_20050	COG1216	Glycosyl transferase, family 2
B1NLA3E_20060	COG1216	Glycosyl transferase, family 2
B1NLA3E_20075	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1NLA3E_20080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_20100	COG0640	Transcriptional regulator
B1NLA3E_20105	COG5658	integral membrane protein
B1NLA3E_20120	COG3037	sugar-specific permease SgaT UlaA
B1NLA3E_20130	COG3711	transcriptional antiterminator
B1NLA3E_20135	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1NLA3E_20140	COG1937	Protein conserved in bacteria
B1NLA3E_20155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_20170	COG2199	diguanylate cyclase activity
B1NLA3E_20170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_20175	COG0346	lactoylglutathione lyase activity
B1NLA3E_20180	COG0071	Belongs to the small heat shock protein (HSP20) family
B1NLA3E_20185	COG0028	Belongs to the TPP enzyme family
B1NLA3E_20210	COG3344	reverse transcriptase
B1NLA3E_20230	COG1482	cell wall glycoprotein biosynthetic process
B1NLA3E_20235	COG1940	carbohydrate kinase activity
B1NLA3E_20255	COG2720	vancomycin resistance protein
B1NLA3E_20275	COG2048	Heterodisulfide reductase, subunit B
B1NLA3E_20280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1NLA3E_20285	COG1053	succinate dehydrogenase
B1NLA3E_20295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B1NLA3E_20295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B1NLA3E_20300	COG0471	metal ion transport
B1NLA3E_20305	COG4565	transcriptional regulatory protein
B1NLA3E_20310	COG3290	protein histidine kinase activity
B1NLA3E_20315	COG3764	Sortase (surface protein transpeptidase)
B1NLA3E_20325	COG1278	Cold shock
B1NLA3E_20345	COG3853	Toxic anion resistance protein (TelA)
B1NLA3E_20350	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
B1NLA3E_20355	COG0833	amino acid
B1NLA3E_20375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1NLA3E_20380	COG1053	succinate dehydrogenase
B1NLA3E_20385	COG2009	succinate dehydrogenase
B1NLA3E_20390	COG1027	Aspartate ammonia-lyase
B1NLA3E_20395	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B1NLA3E_20405	COG4191	Histidine kinase
B1NLA3E_20410	COG0784	Response regulator, receiver
B1NLA3E_20415	COG1609	Transcriptional regulator
B1NLA3E_20420	COG1979	alcohol dehydrogenase
B1NLA3E_20430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1NLA3E_20435	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B1NLA3E_20440	COG0800	Aldolase
B1NLA3E_20445	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_20450	COG2731	YhcH YjgK YiaL family protein
B1NLA3E_20455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1NLA3E_20460	COG0675	Transposase, IS605 OrfB family
B1NLA3E_20475	COG2267	carboxylic ester hydrolase activity
B1NLA3E_20485	COG0243	molybdopterin cofactor binding
B1NLA3E_20495	COG0494	nUDIX hydrolase
B1NLA3E_20505	COG0183	Belongs to the thiolase family
B1NLA3E_20530	COG0425	Belongs to the sulfur carrier protein TusA family
B1NLA3E_20530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_20540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_20540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_20545	COG0730	response to heat
B1NLA3E_20550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B1NLA3E_20555	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1NLA3E_20605	COG1131	(ABC) transporter
B1NLA3E_20610	COG1309	transcriptional regulator
B1NLA3E_20615	COG2814	Major facilitator Superfamily
B1NLA3E_20630	COG1126	abc transporter atp-binding protein
B1NLA3E_20635	COG0765	amino acid transport
B1NLA3E_20640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_20645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_20660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1NLA3E_20665	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_20680	COG0398	Pfam SNARE associated Golgi protein
B1NLA3E_20685	COG2199	diguanylate cyclase activity
B1NLA3E_20685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_20690	COG3223	Belongs to the PsiE family
B1NLA3E_20700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_20705	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_20710	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_20730	COG2259	Doxx family
B1NLA3E_20735	COG1846	Transcriptional regulator
B1NLA3E_20745	COG1126	abc transporter atp-binding protein
B1NLA3E_20750	COG0765	amino acid transport
B1NLA3E_20755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_20800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_20805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_20815	COG1733	regulation of RNA biosynthetic process
B1NLA3E_20845	COG0606	chelatase, subunit chli
B1NLA3E_20850	COG0252	asparaginase activity
B1NLA3E_20925	COG1086	Polysaccharide biosynthesis protein
B1NLA3E_20940	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1NLA3E_20945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1NLA3E_20950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_20960	COG4464	protein tyrosine phosphatase activity
B1NLA3E_20965	COG0489	protein tyrosine kinase activity
B1NLA3E_20970	COG3944	biosynthesis protein
B1NLA3E_20975	COG1388	LysM domain
B1NLA3E_20975	COG0791	NLP P60 protein
B1NLA3E_20980	COG1785	Belongs to the alkaline phosphatase family
B1NLA3E_20985	COG1904	glucuronate isomerase
B1NLA3E_20990	COG1609	Transcriptional regulator
B1NLA3E_20995	COG0246	Mannitol dehydrogenase
B1NLA3E_21000	COG2721	sulfolactate sulfo-lyase activity
B1NLA3E_21005	COG0800	Aldolase
B1NLA3E_21020	COG3958	Transketolase
B1NLA3E_21025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B1NLA3E_21035	COG1175	transmembrane transport
B1NLA3E_21045	COG2188	Transcriptional regulator
B1NLA3E_21055	COG4715	Zinc finger, swim domain protein
B1NLA3E_21060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1NLA3E_21090	COG2894	cell division
B1NLA3E_21140	COG0366	Alpha amylase catalytic
B1NLA3E_21165	COG0577	efflux transmembrane transporter activity
B1NLA3E_21180	COG3842	ATPase activity
B1NLA3E_21195	COG0629	single-stranded DNA binding
B1NLA3E_21220	COG1077	Cell shape determining protein MreB Mrl
B1NLA3E_21225	COG1609	Transcriptional regulator
B1NLA3E_21230	COG3829	transcription factor binding
B1NLA3E_21245	COG2271	Major facilitator Superfamily
B1NLA3E_21260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B1NLA3E_21265	COG0644	oxidoreductase
B1NLA3E_21270	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_21275	COG2086	electron transfer activity
B1NLA3E_21280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1NLA3E_21285	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_21290	COG0657	acetylesterase activity
B1NLA3E_21300	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1NLA3E_21305	COG0768	penicillin binding
B1NLA3E_21310	COG0739	heme binding
B1NLA3E_21320	COG2385	sporulation resulting in formation of a cellular spore
B1NLA3E_21335	COG4836	Membrane
B1NLA3E_21345	COG1007	ATP synthesis coupled electron transport
B1NLA3E_21355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1NLA3E_21360	COG0713	ATP synthesis coupled electron transport
B1NLA3E_21365	COG0839	Belongs to the complex I subunit 6 family
B1NLA3E_21375	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1NLA3E_21385	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_21390	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_21395	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_21405	COG0191	fructose-bisphosphate aldolase activity
B1NLA3E_21425	COG0205	6-phosphofructokinase activity
B1NLA3E_21430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_21440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B1NLA3E_21445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B1NLA3E_21455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1NLA3E_21460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B1NLA3E_21465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1NLA3E_21470	COG0356	it plays a direct role in the translocation of protons across the membrane
B1NLA3E_21485	COG1404	Belongs to the peptidase S8 family
B1NLA3E_21495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B1NLA3E_21500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1NLA3E_21510	COG0698	ribose 5-phosphate isomerase
B1NLA3E_21520	COG1971	Probably functions as a manganese efflux pump
B1NLA3E_21525	COG0009	L-threonylcarbamoyladenylate synthase
B1NLA3E_21535	COG2890	protein-(glutamine-N5) methyltransferase activity
B1NLA3E_21540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B1NLA3E_21550	COG0243	molybdopterin cofactor binding
B1NLA3E_21555	COG0437	4 iron, 4 sulfur cluster binding
B1NLA3E_21580	COG1435	thymidine kinase activity
B1NLA3E_21590	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B1NLA3E_21595	COG1494	fructose-1,6-bisphosphatase
B1NLA3E_21600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B1NLA3E_21605	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1NLA3E_21610	COG0191	fructose-bisphosphate aldolase activity
B1NLA3E_21615	COG2204	response regulator
B1NLA3E_21620	COG4821	SIS domain
B1NLA3E_21640	COG1703	isobutyryl-CoA mutase activity
B1NLA3E_21640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_21640	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_21650	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_21655	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_21660	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1NLA3E_21665	COG0183	Belongs to the thiolase family
B1NLA3E_21670	COG0247	lactate metabolic process
B1NLA3E_21670	COG2181	nitrate reductase activity
B1NLA3E_21675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_21695	COG0018	arginyl-trna synthetase
B1NLA3E_21700	COG4506	Protein conserved in bacteria
B1NLA3E_21705	COG0010	Belongs to the arginase family
B1NLA3E_21710	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B1NLA3E_21715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1NLA3E_21725	COG1994	Peptidase M50
B1NLA3E_21735	COG3465	dGTPase activity
B1NLA3E_21740	COG1078	dGTPase activity
B1NLA3E_21760	COG0280	phosphate acetyltransferase
B1NLA3E_21775	COG2363	Small membrane protein
B1NLA3E_21785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_21795	COG0314	molybdopterin synthase activity
B1NLA3E_21800	COG1910	domain protein
B1NLA3E_21805	COG0303	'Molybdopterin
B1NLA3E_21810	COG0746	molybdenum cofactor guanylyltransferase activity
B1NLA3E_21825	COG0437	4 iron, 4 sulfur cluster binding
B1NLA3E_21840	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B1NLA3E_21845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1NLA3E_21850	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1NLA3E_21860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_21875	COG0561	phosphatase activity
B1NLA3E_21885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B1NLA3E_21890	COG0723	plastoquinol--plastocyanin reductase activity
B1NLA3E_21890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1NLA3E_21905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_21920	COG0788	formyltetrahydrofolate deformylase activity
B1NLA3E_21935	COG2197	response regulator
B1NLA3E_21940	COG1131	(ABC) transporter
B1NLA3E_21960	COG2195	Cleaves the N-terminal amino acid of tripeptides
B1NLA3E_21965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B1NLA3E_21975	COG1187	pseudouridine synthase activity
B1NLA3E_22015	COG0579	oxidoreductase
B1NLA3E_22025	COG1114	Component of the transport system for branched-chain amino acids
B1NLA3E_22040	COG1215	transferase activity, transferring glycosyl groups
B1NLA3E_22055	COG3437	response regulator, receiver
B1NLA3E_22055	COG2770	Histidine kinase
B1NLA3E_22060	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B1NLA3E_22090	COG3290	protein histidine kinase activity
B1NLA3E_22105	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1NLA3E_22120	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B1NLA3E_22130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_22135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B1NLA3E_22140	COG4853	Protein conserved in bacteria
B1NLA3E_22145	COG4863	YycH protein
B1NLA3E_22150	COG5002	protein histidine kinase activity
B1NLA3E_22155	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_22160	COG1388	LysM domain
B1NLA3E_22160	COG4942	peptidase
B1NLA3E_22165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B1NLA3E_22170	COG0305	Participates in initiation and elongation during chromosome replication
B1NLA3E_22175	COG0359	binds to the 23S rRNA
B1NLA3E_22180	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B1NLA3E_22185	COG4241	membrane
B1NLA3E_22190	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B1NLA3E_22200	COG0360	Binds together with S18 to 16S ribosomal RNA
B1NLA3E_22205	COG0012	GTP binding
B1NLA3E_22210	COG4481	Protein conserved in bacteria
B1NLA3E_22215	COG0668	transmembrane transport
B1NLA3E_22245	COG1475	DNA binding
B1NLA3E_22250	COG1192	Involved in chromosome partitioning
B1NLA3E_22255	COG1475	DNA binding
B1NLA3E_22260	COG0357	Ribosomal RNA small subunit methyltransferase G
B1NLA3E_22265	COG0445	tRNA wobble uridine modification
B1NLA3E_22270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B1NLA3E_22275	COG1847	R3H domain protein
B1NLA3E_22285	COG0594	ribonuclease P activity