locus-tag	class	description
CJO35_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO35_00010	COG0592	DNA-directed DNA polymerase activity
CJO35_00015	COG2501	S4 domain
CJO35_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJO35_00030	COG0187	DNA topoisomerase II activity
CJO35_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJO35_00070	COG0517	IMP dehydrogenase activity
CJO35_00070	COG0516	GMP reductase activity
CJO35_00075	COG1686	Belongs to the peptidase S11 family
CJO35_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CJO35_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CJO35_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJO35_00095	COG1929	Belongs to the glycerate kinase type-1 family
CJO35_00100	COG2610	gluconate transmembrane transporter activity
CJO35_00105	COG3835	regulator
CJO35_00120	COG1428	Deoxynucleoside kinase
CJO35_00125	COG1428	Deoxynucleoside kinase
CJO35_00130	COG1388	LysM domain
CJO35_00130	COG3858	chitin binding
CJO35_00135	COG1335	isochorismatase
CJO35_00140	COG0590	tRNA wobble adenosine to inosine editing
CJO35_00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CJO35_00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CJO35_00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJO35_00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CJO35_00210	COG3853	Toxic anion resistance protein (TelA)
CJO35_00215	COG1982	Orn Lys Arg decarboxylase major
CJO35_00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJO35_00225	COG3870	Protein conserved in bacteria
CJO35_00230	COG1728	Protein conserved in bacteria
CJO35_00235	COG0470	DNA polymerase III
CJO35_00240	COG1774	PSP1 C-terminal conserved region
CJO35_00245	COG4467	Involved in initiation control of chromosome replication
CJO35_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CJO35_00255	COG2827	Endonuclease containing a URI domain
CJO35_00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJO35_00265	COG2002	toxin-antitoxin pair type II binding
CJO35_00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_00275	COG0084	hydrolase, TatD family'
CJO35_00280	COG3583	domain protein
CJO35_00280	COG3584	3D domain protein
CJO35_00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CJO35_00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJO35_00300	COG4466	Protein conserved in bacteria
CJO35_00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CJO35_00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO35_00320	COG0251	oxidation-reduction process
CJO35_00325	COG2088	sporulation resulting in formation of a cellular spore
CJO35_00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJO35_00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CJO35_00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJO35_00345	COG0193	aminoacyl-tRNA hydrolase activity
CJO35_00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJO35_00360	COG2002	toxin-antitoxin pair type II binding
CJO35_00365	COG2244	polysaccharide biosynthetic process
CJO35_00370	COG3956	TIGRFAM MazG family protein
CJO35_00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CJO35_00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CJO35_00395	COG1098	S1 RNA binding domain
CJO35_00410	COG2208	phosphoserine phosphatase activity
CJO35_00415	COG2304	oxidoreductase activity
CJO35_00420	COG0515	serine threonine protein kinase
CJO35_00425	COG0037	tRNA processing
CJO35_00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO35_00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJO35_00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CJO35_00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO35_00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO35_00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJO35_00470	COG0512	Glutamine amidotransferase of anthranilate synthase
CJO35_00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJO35_00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJO35_00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CJO35_00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CJO35_00495	COG1396	sequence-specific DNA binding
CJO35_00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CJO35_00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJO35_00585	COG4463	regulation of RNA biosynthetic process
CJO35_00590	COG3880	PFAM UvrB UvrC protein
CJO35_00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CJO35_00600	COG0542	response to heat
CJO35_00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CJO35_00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CJO35_00615	COG4956	integral membrane protein (PIN domain superfamily)
CJO35_00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CJO35_00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CJO35_00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO35_00635	COG1045	serine acetyltransferase
CJO35_00640	COG0215	cysteine-tRNA ligase activity
CJO35_00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CJO35_00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO35_00655	COG3688	RNA-binding protein containing a PIN domain
CJO35_00665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO35_00675	COG0250	Participates in transcription elongation, termination and antitermination
CJO35_00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJO35_00685	COG0081	regulation of translation
CJO35_00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJO35_00695	COG0222	ribosome binding
CJO35_00700	COG2813	Specifically methylates the guanine in position
CJO35_00705	COG0085	RNA polymerase activity
CJO35_00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJO35_00715	COG1358	cellular component organization or biogenesis
CJO35_00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJO35_00725	COG0049	tRNA binding
CJO35_00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJO35_00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJO35_00740	COG0051	transcription antitermination factor activity, RNA binding
CJO35_00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJO35_00750	COG0088	Forms part of the polypeptide exit tunnel
CJO35_00755	COG0089	rRNA binding
CJO35_00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJO35_00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJO35_00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJO35_00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJO35_00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJO35_00785	COG0255	Belongs to the universal ribosomal protein uL29 family
CJO35_00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJO35_00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJO35_00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CJO35_00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJO35_00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO35_00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJO35_00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJO35_00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CJO35_00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJO35_00835	COG1841	ribosomal large subunit assembly
CJO35_00840	COG0200	Binds to the 23S rRNA
CJO35_00845	COG0201	protein transport
CJO35_00850	COG0563	adenylate kinase activity
CJO35_00855	COG0024	Methionine aminopeptidase
CJO35_00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
CJO35_00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJO35_00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJO35_00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJO35_00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJO35_00885	COG0202	RNA polymerase activity
CJO35_00890	COG0203	ribosomal protein L17
CJO35_00895	COG1122	ATPase activity
CJO35_00900	COG1122	ATPase activity
CJO35_00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CJO35_00910	COG0101	tRNA pseudouridine synthase activity
CJO35_00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJO35_00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJO35_00925	COG2318	DinB family
CJO35_00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_00940	COG0489	protein tyrosine kinase activity
CJO35_00950	COG2194	sulfuric ester hydrolase activity
CJO35_00955	COG0726	polysaccharide deacetylase
CJO35_00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJO35_00995	COG0385	Bile acid
CJO35_01010	COG3876	Protein conserved in bacteria
CJO35_01015	COG1472	Belongs to the glycosyl hydrolase 3 family
CJO35_01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJO35_01025	COG1263	PTS System
CJO35_01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_01030	COG1737	Transcriptional regulator
CJO35_01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CJO35_01040	COG1683	Conserved Protein
CJO35_01075	COG1595	DNA-templated transcription, initiation
CJO35_01080	COG5662	AntiSigma factor
CJO35_01085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CJO35_01090	COG4856	YbbR-like protein
CJO35_01095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJO35_01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJO35_01120	COG1725	Transcriptional regulator
CJO35_01125	COG0640	Transcriptional regulator
CJO35_01130	COG2814	Major facilitator Superfamily
CJO35_01140	COG1132	(ABC) transporter
CJO35_01145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CJO35_01170	COG1011	Hydrolase
CJO35_01175	COG1113	amino acid transport
CJO35_01180	COG2851	Citrate transporter
CJO35_01185	COG3181	Tripartite tricarboxylate transporter family receptor
CJO35_01190	COG4565	transcriptional regulatory protein
CJO35_01195	COG3290	protein histidine kinase activity
CJO35_01210	COG2211	Major facilitator Superfamily
CJO35_01230	COG1331	Highly conserved protein containing a thioredoxin domain
CJO35_01235	COG3677	Transposase
CJO35_01275	COG1331	Highly conserved protein containing a thioredoxin domain
CJO35_01285	COG0477	Major facilitator Superfamily
CJO35_01305	COG1283	sodium-dependent phosphate transmembrane transporter activity
CJO35_01310	COG4682	membrane
CJO35_01335	COG0697	spore germination
CJO35_01340	COG2207	Transcriptional regulator
CJO35_01340	COG1917	Cupin 2, conserved barrel domain protein
CJO35_01360	COG0371	Dehydrogenase
CJO35_01365	COG0840	transmembrane signaling receptor activity
CJO35_01370	COG4213	ABC transporter substrate-binding protein
CJO35_01385	COG4257	antibiotic catabolic process
CJO35_01395	COG0833	amino acid
CJO35_01400	COG2040	homocysteine
CJO35_01410	COG1263	PTS System
CJO35_01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_01410	COG2190	(PTS) system
CJO35_01415	COG0789	Transcriptional regulator
CJO35_01420	COG2323	membrane
CJO35_01435	COG2205	protein histidine kinase activity
CJO35_01440	COG1115	amino acid carrier protein
CJO35_01445	COG2066	Belongs to the glutaminase family
CJO35_01450	COG4191	Histidine kinase
CJO35_01455	COG0784	Response regulator, receiver
CJO35_01480	COG3540	Alkaline phosphatase
CJO35_01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO35_01490	COG0805	protein transport
CJO35_01495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO35_01500	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_01505	COG2271	Major facilitator Superfamily
CJO35_01510	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_01515	COG2186	Transcriptional regulator
CJO35_01520	COG2721	sulfolactate sulfo-lyase activity
CJO35_01525	COG0745	RESPONSE REGULATOR receiver
CJO35_01530	COG2205	protein histidine kinase activity
CJO35_01535	COG1131	(ABC) transporter
CJO35_01560	COG3173	Aminoglycoside phosphotransferase
CJO35_01565	COG1846	Transcriptional regulator
CJO35_01570	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_01590	COG0789	Transcriptional regulator
CJO35_01620	COG1714	RDD family
CJO35_01625	COG1405	negative regulation of cell septum assembly
CJO35_01625	COG3012	SEC-C Motif Domain Protein
CJO35_01655	COG0583	DNA-binding transcription factor activity
CJO35_01660	COG1942	4-Oxalocrotonate Tautomerase
CJO35_01680	COG1288	antiporter activity
CJO35_01690	COG0456	acetyltransferase
CJO35_01700	COG1164	Oligoendopeptidase f
CJO35_01705	COG2261	transglycosylase associated protein
CJO35_01715	COG0247	lactate metabolic process
CJO35_01720	COG0277	FAD linked oxidase domain protein
CJO35_01725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_01730	COG1447	Phosphotransferase system cellobiose-specific component IIA
CJO35_01735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_01740	COG1486	melibiose metabolic process
CJO35_01750	COG3394	polysaccharide catabolic process
CJO35_01765	COG3591	Belongs to the peptidase S1B family
CJO35_01770	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_01780	COG1595	DNA-templated transcription, initiation
CJO35_01790	COG3773	Cell wall hydrolase
CJO35_01795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_01800	COG3883	PFAM NLP P60 protein
CJO35_01800	COG0791	NLP P60 protein
CJO35_01810	COG1131	(ABC) transporter
CJO35_01815	COG1309	transcriptional regulator
CJO35_01835	COG2310	stress, protein
CJO35_01840	COG2310	stress, protein
CJO35_01845	COG2310	stress, protein
CJO35_01850	COG0861	Integral membrane protein TerC family
CJO35_01870	COG3853	Toxic anion resistance protein (TelA)
CJO35_01875	COG0785	Cytochrome C biogenesis protein
CJO35_01885	COG0789	Transcriptional regulator
CJO35_01890	COG2223	nitrite transmembrane transporter activity
CJO35_01895	COG0039	L-malate dehydrogenase activity
CJO35_01900	COG1620	l-lactate permease
CJO35_01905	COG1280	lysine exporter protein (LysE YggA)
CJO35_01910	COG1113	amino acid transport
CJO35_01915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CJO35_01920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CJO35_01925	COG3541	Predicted nucleotidyltransferase
CJO35_01930	COG0506	proline dehydrogenase activity
CJO35_01935	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_01940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_01945	COG2508	Transcriptional regulator
CJO35_01950	COG3689	TIGRFAM TIGR03943 family protein
CJO35_01955	COG0701	Predicted permease
CJO35_01960	COG3458	cephalosporin-C deacetylase activity
CJO35_01980	COG0765	amino acid transport
CJO35_01985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO35_01990	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJO35_02000	COG2723	6-phospho-beta-galactosidase activity
CJO35_02010	COG3209	COG3209 Rhs family protein
CJO35_02015	COG0515	serine threonine protein kinase
CJO35_02015	COG3266	domain, Protein
CJO35_02025	COG5444	nuclease activity
CJO35_02050	COG1176	ABC-type spermidine putrescine transport system, permease component I
CJO35_02055	COG1177	transmembrane transport
CJO35_02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_02070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_02075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CJO35_02080	COG0697	spore germination
CJO35_02085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_02095	COG2819	hydrolase of the alpha beta superfamily
CJO35_02105	COG2364	Membrane
CJO35_02115	COG1131	(ABC) transporter
CJO35_02140	COG1126	abc transporter atp-binding protein
CJO35_02145	COG0765	amino acid transport
CJO35_02150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO35_02155	COG3829	transcription factor binding
CJO35_02160	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO35_02165	COG0833	amino acid
CJO35_02170	COG0010	Belongs to the arginase family
CJO35_02175	COG0583	DNA-binding transcription factor activity
CJO35_02180	COG0163	prenyltransferase activity
CJO35_02185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CJO35_02235	COG5444	nuclease activity
CJO35_02255	COG2972	Histidine kinase
CJO35_02260	COG4753	response regulator
CJO35_02260	COG2207	Transcriptional regulator
CJO35_02265	COG4213	ABC transporter substrate-binding protein
CJO35_02275	COG4214	carbohydrate transport
CJO35_02280	COG2271	Major facilitator Superfamily
CJO35_02285	COG1846	Transcriptional regulator
CJO35_02285	COG0456	acetyltransferase
CJO35_02290	COG1874	Beta-galactosidase
CJO35_02300	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CJO35_02305	COG3104	oligopeptide transport
CJO35_02310	COG5434	Belongs to the glycosyl hydrolase 28 family
CJO35_02320	COG0697	spore germination
CJO35_02330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CJO35_02340	COG1136	(ABC) transporter
CJO35_02345	COG0577	efflux transmembrane transporter activity
CJO35_02350	COG0745	RESPONSE REGULATOR receiver
CJO35_02355	COG5002	protein histidine kinase activity
CJO35_02355	COG3850	Histidine kinase
CJO35_02360	COG0840	transmembrane signaling receptor activity
CJO35_02365	COG0527	aspartate kinase activity
CJO35_02370	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_02375	COG4605	iron ion homeostasis
CJO35_02380	COG4604	ABC transporter, ATP-binding protein
CJO35_02385	COG4607	ABC-type enterochelin transport system periplasmic component
CJO35_02390	COG2814	Major facilitator Superfamily
CJO35_02395	COG1309	transcriptional regulator
CJO35_02405	COG0778	Nitroreductase
CJO35_02410	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CJO35_02415	COG0640	Transcriptional regulator
CJO35_02420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_02425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CJO35_02430	COG0531	amino acid
CJO35_02435	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_02440	COG0697	spore germination
CJO35_02450	COG4549	nuclear export factor GLE1
CJO35_02455	COG1276	copper resistance
CJO35_02455	COG2372	response to copper ion
CJO35_02460	COG1349	DNA-binding transcription factor activity
CJO35_02465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO35_02470	COG0243	molybdopterin cofactor binding
CJO35_02475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO35_02480	COG2146	nitrite reductase [NAD(P)H] activity
CJO35_02485	COG1587	Uroporphyrinogen-III synthase
CJO35_02485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJO35_02490	COG1802	Transcriptional regulator
CJO35_02495	COG0471	metal ion transport
CJO35_02500	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO35_02505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO35_02520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_02535	COG3959	Transketolase, thiamine diphosphate binding domain
CJO35_02540	COG3958	Transketolase
CJO35_02545	COG0561	phosphatase activity
CJO35_02550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CJO35_02555	COG1914	H( )-stimulated, divalent metal cation uptake system
CJO35_02560	COG4336	lyase activity
CJO35_02565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CJO35_02570	COG1984	allophanate hydrolase subunit 2
CJO35_02575	COG1414	Transcriptional regulator
CJO35_02580	COG2755	lipolytic protein G-D-S-L family
CJO35_02585	COG2213	PTS system mannitol-specific
CJO35_02590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_02595	COG0246	Mannitol dehydrogenase
CJO35_02600	COG3711	transcriptional antiterminator
CJO35_02605	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_02610	COG1917	Cupin 2, conserved barrel domain protein
CJO35_02620	COG3871	stress protein (general stress protein 26)
CJO35_02630	COG1316	TRANSCRIPTIONal
CJO35_02635	COG2814	Major facilitator Superfamily
CJO35_02645	COG1522	sequence-specific DNA binding
CJO35_02650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJO35_02650	COG0551	DNA topoisomerase type I activity
CJO35_02655	COG0531	amino acid
CJO35_02660	COG0028	Belongs to the TPP enzyme family
CJO35_02675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_02680	COG1914	H( )-stimulated, divalent metal cation uptake system
CJO35_02685	COG2261	transglycosylase associated protein
CJO35_02690	COG1027	Aspartate ammonia-lyase
CJO35_02695	COG1819	glycosyl
CJO35_02700	COG4876	unkown
CJO35_02705	COG2217	Heavy metal translocating P-type atpase
CJO35_02715	COG0662	Cupin 2, conserved barrel domain protein
CJO35_02720	COG3729	General stress protein
CJO35_02725	COG0628	permease
CJO35_02730	COG1301	dicarboxylic acid transport
CJO35_02735	COG1131	(ABC) transporter
CJO35_02740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_02750	COG1960	acyl-CoA dehydrogenase activity
CJO35_02765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_02770	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJO35_02775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJO35_02785	COG0513	Belongs to the DEAD box helicase family
CJO35_02790	COG3402	PFAM membrane-flanked domain
CJO35_02795	COG3428	Bacterial PH domain
CJO35_02800	COG0705	Rhomboid family
CJO35_02805	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CJO35_02810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJO35_02815	COG0864	Transcriptional regulator
CJO35_02820	COG2337	Toxic component of a toxin-antitoxin (TA) module
CJO35_02825	COG1366	Belongs to the anti-sigma-factor antagonist family
CJO35_02830	COG1366	Belongs to the anti-sigma-factor antagonist family
CJO35_02835	COG2172	sigma factor antagonist activity
CJO35_02840	COG2208	phosphoserine phosphatase activity
CJO35_02850	COG2172	sigma factor antagonist activity
CJO35_02855	COG1191	sigma factor activity
CJO35_02860	COG2208	phosphoserine phosphatase activity
CJO35_02865	COG2183	response to ionizing radiation
CJO35_02870	COG1309	transcriptional regulator
CJO35_02875	COG2409	Drug exporters of the RND superfamily
CJO35_02875	COG1033	growth of symbiont in host cell
CJO35_02885	COG3091	SprT-like family
CJO35_02935	COG1476	TRANSCRIPTIONal
CJO35_02940	COG3239	Fatty acid desaturase
CJO35_02945	COG1278	Cold shock
CJO35_02950	COG1063	alcohol dehydrogenase
CJO35_02960	COG2364	Membrane
CJO35_02965	COG1846	Transcriptional regulator
CJO35_02970	COG0456	acetyltransferase
CJO35_02975	COG2808	Putative FMN-binding domain
CJO35_02985	COG1733	regulation of RNA biosynthetic process
CJO35_02990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_03000	COG0583	DNA-binding transcription factor activity
CJO35_03015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CJO35_03020	COG1113	amino acid transport
CJO35_03035	COG1595	DNA-templated transcription, initiation
CJO35_03045	COG2755	lipolytic protein G-D-S-L family
CJO35_03045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJO35_03050	COG2814	Major facilitator Superfamily
CJO35_03055	COG2972	Histidine kinase
CJO35_03055	COG0745	RESPONSE REGULATOR receiver
CJO35_03060	COG3279	Response regulator of the LytR AlgR family
CJO35_03070	COG3764	Sortase (surface protein transpeptidase)
CJO35_03075	COG2814	Major facilitator Superfamily
CJO35_03115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CJO35_03120	COG0802	atpase or kinase
CJO35_03125	COG1214	PFAM Peptidase M22, glycoprotease
CJO35_03130	COG0456	acetyltransferase
CJO35_03135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJO35_03140	COG0488	(ABC) transporter
CJO35_03145	COG0315	cyclic pyranopterin monophosphate synthase activity
CJO35_03150	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CJO35_03155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO35_03160	COG0805	protein transport
CJO35_03170	COG1266	CAAX protease self-immunity
CJO35_03175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJO35_03180	COG0459	protein refolding
CJO35_03215	COG2720	vancomycin resistance protein
CJO35_03230	COG2135	peptidase activity
CJO35_03240	COG1309	transcriptional regulator
CJO35_03245	COG0574	Belongs to the PEP-utilizing enzyme family
CJO35_03245	COG3848	Pyruvate phosphate dikinase
CJO35_03255	COG3189	MarR family transcriptional regulator
CJO35_03260	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CJO35_03265	COG2272	Belongs to the type-B carboxylesterase lipase family
CJO35_03270	COG2814	Major facilitator Superfamily
CJO35_03275	COG1842	Phage shock protein A
CJO35_03280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJO35_03285	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CJO35_03290	COG4260	virion core protein, lumpy skin disease virus
CJO35_03300	COG1378	Sugar-specific transcriptional regulator TrmB
CJO35_03305	COG1280	lysine exporter protein (LysE YggA)
CJO35_03310	COG3339	Conserved Protein
CJO35_03315	COG0772	Belongs to the SEDS family
CJO35_03320	COG0772	Belongs to the SEDS family
CJO35_03345	COG0726	polysaccharide deacetylase
CJO35_03355	COG1609	Transcriptional regulator
CJO35_03360	COG0366	Alpha amylase catalytic
CJO35_03365	COG2182	Extracellular solute-binding protein
CJO35_03370	COG1175	transmembrane transport
CJO35_03375	COG3833	ABC-type maltose transport systems, permease component
CJO35_03380	COG5521	maltodextrose utilization protein MalA
CJO35_03385	COG1554	hydrolase, family 65, central catalytic
CJO35_03390	COG0366	Alpha amylase catalytic
CJO35_03395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO35_03400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJO35_03405	COG1846	Transcriptional regulator
CJO35_03420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CJO35_03425	COG0823	Involved in the tonB-independent uptake of proteins
CJO35_03455	COG0702	epimerase
CJO35_03465	COG2132	Multicopper oxidase
CJO35_03480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CJO35_03485	COG0714	Associated with various cellular activities
CJO35_03490	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CJO35_03495	COG1305	Transglutaminase-like
CJO35_03500	COG0519	Catalyzes the synthesis of GMP from XMP
CJO35_03500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJO35_03510	COG2252	PERMEase
CJO35_03525	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CJO35_03535	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJO35_03540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJO35_03545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CJO35_03550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CJO35_03555	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO35_03560	COG0047	phosphoribosylformylglycinamidine synthase activity
CJO35_03565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO35_03570	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CJO35_03575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJO35_03580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJO35_03585	COG0138	bifunctional purine biosynthesis protein purh
CJO35_03590	COG0151	Belongs to the GarS family
CJO35_03605	COG2124	cytochrome p450
CJO35_03625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJO35_03630	COG1470	cell adhesion involved in biofilm formation
CJO35_03635	COG4496	protein, YerC YecD
CJO35_03640	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CJO35_03645	COG0210	DNA helicase
CJO35_03650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJO35_03655	COG4851	CamS sex pheromone cAM373 precursor
CJO35_03660	COG2188	Transcriptional regulator
CJO35_03680	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CJO35_03685	COG0626	cystathionine gamma-synthase activity
CJO35_03690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CJO35_03695	COG3457	Alanine racemase
CJO35_03700	COG0363	glucosamine-6-phosphate deaminase activity
CJO35_03705	COG1285	pathogenesis
CJO35_03710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_03715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO35_03720	COG0154	amidase activity
CJO35_03725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO35_03745	COG1309	transcriptional regulator
CJO35_03750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CJO35_03760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_03765	COG1957	nucleoside hydrolase
CJO35_03770	COG1597	lipid kinase activity
CJO35_03775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJO35_03795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_03795	COG2190	(PTS) system
CJO35_03795	COG1263	PTS System
CJO35_03800	COG2723	6-phospho-beta-galactosidase activity
CJO35_03805	COG3711	transcriptional antiterminator
CJO35_03810	COG0457	Tetratricopeptide repeat
CJO35_03830	COG0217	transcriptional regulatory protein
CJO35_03845	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_03850	COG0840	transmembrane signaling receptor activity
CJO35_03855	COG0471	metal ion transport
CJO35_03860	COG0488	(ABC) transporter
CJO35_03865	COG1469	GTP cyclohydrolase I activity
CJO35_03880	COG0523	cobalamin synthesis protein
CJO35_03885	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CJO35_03890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO35_03895	COG0156	8-amino-7-oxononanoate synthase activity
CJO35_03900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CJO35_03905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJO35_03910	COG2124	cytochrome p450
CJO35_03920	COG0789	Transcriptional regulator
CJO35_03925	COG2814	Major facilitator Superfamily
CJO35_03930	COG0488	(ABC) transporter
CJO35_03935	COG0513	Belongs to the DEAD box helicase family
CJO35_03940	COG2130	NADP-dependent
CJO35_03955	COG0471	metal ion transport
CJO35_03975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_03985	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CJO35_03990	COG5658	integral membrane protein
CJO35_03995	COG0640	Transcriptional regulator
CJO35_04000	COG1254	Belongs to the acylphosphatase family
CJO35_04005	COG2258	MOSC domain
CJO35_04020	COG0024	Methionine aminopeptidase
CJO35_04025	COG1368	sulfuric ester hydrolase activity
CJO35_04035	COG1115	amino acid carrier protein
CJO35_04040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_04040	COG1263	PTS System
CJO35_04045	COG0366	Alpha amylase catalytic
CJO35_04050	COG2188	Transcriptional regulator
CJO35_04075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO35_04080	COG1045	serine acetyltransferase
CJO35_04085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO35_04095	COG1215	transferase activity, transferring glycosyl groups
CJO35_04100	COG0463	Glycosyl transferase, family 2
CJO35_04100	COG0457	Tetratricopeptide repeat
CJO35_04110	COG0673	inositol 2-dehydrogenase activity
CJO35_04125	COG1733	regulation of RNA biosynthetic process
CJO35_04130	COG0778	Nitroreductase
CJO35_04135	COG0737	Belongs to the 5'-nucleotidase family
CJO35_04140	COG0693	protein deglycase activity
CJO35_04145	COG4840	Belongs to the UPF0435 family
CJO35_04150	COG1115	amino acid carrier protein
CJO35_04155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO35_04160	COG4980	gas vesicle protein
CJO35_04165	COG1295	ribonuclease BN
CJO35_04170	COG0477	Major facilitator Superfamily
CJO35_04180	COG0387	Pfam Sodium calcium exchanger
CJO35_04190	COG0535	radical SAM domain protein
CJO35_04200	COG0726	polysaccharide deacetylase
CJO35_04205	COG0371	Dehydrogenase
CJO35_04215	COG0598	Magnesium transport protein CorA
CJO35_04220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CJO35_04225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJO35_04230	COG4637	Psort location Cytoplasmic, score
CJO35_04255	COG1819	glycosyl
CJO35_04265	COG0477	Major facilitator Superfamily
CJO35_04270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_04270	COG1263	PTS System
CJO35_04275	COG3711	transcriptional antiterminator
CJO35_04280	COG0288	reversible hydration of carbon dioxide
CJO35_04285	COG3002	Belongs to the UPF0753 family
CJO35_04290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CJO35_04295	COG5609	conserved protein (DUF2294)
CJO35_04305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO35_04310	COG0022	dehydrogenase e1 component
CJO35_04315	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_04320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO35_04325	COG3284	Transcriptional regulator
CJO35_04330	COG1742	UPF0060 membrane protein
CJO35_04335	COG1486	melibiose metabolic process
CJO35_04340	COG1737	Transcriptional regulator
CJO35_04345	COG1263	PTS System
CJO35_04345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_04360	COG1733	regulation of RNA biosynthetic process
CJO35_04365	COG2259	Doxx family
CJO35_04370	COG2514	catechol 2,3-dioxygenase activity
CJO35_04380	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_04385	COG2207	Transcriptional regulator
CJO35_04385	COG1917	Cupin 2, conserved barrel domain protein
CJO35_04390	COG1653	transport
CJO35_04400	COG1051	belongs to the nudix hydrolase family
CJO35_04415	COG0392	lysyltransferase activity
CJO35_04415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CJO35_04420	COG0384	phenazine biosynthesis protein PhzF
CJO35_04425	COG0778	Nitroreductase
CJO35_04445	COG1090	epimerase
CJO35_04450	COG2137	regulation of response to DNA damage stimulus
CJO35_04480	COG0463	Glycosyl transferase, family 2
CJO35_04490	COG4485	Bacterial membrane protein, YfhO
CJO35_04495	COG1988	membrane-bound metal-dependent
CJO35_04500	COG1194	a g-specific adenine glycosylase
CJO35_04510	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_04525	COG3557	Belongs to the UPF0374 family
CJO35_04530	COG1132	(ABC) transporter
CJO35_04535	COG0444	Belongs to the ABC transporter superfamily
CJO35_04540	COG4608	Belongs to the ABC transporter superfamily
CJO35_04545	COG0747	negative chemotaxis
CJO35_04560	COG4129	membrane
CJO35_04565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJO35_04570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJO35_04575	COG0735	belongs to the Fur family
CJO35_04685	COG0457	Tetratricopeptide repeat
CJO35_04730	COG5444	nuclease activity
CJO35_04735	COG0457	Tetratricopeptide repeat
CJO35_04740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJO35_04750	COG0710	3-dehydroquinate dehydratase activity
CJO35_04755	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CJO35_04760	COG1116	anion transmembrane transporter activity
CJO35_04765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO35_04770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO35_04775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_04785	COG1476	TRANSCRIPTIONal
CJO35_04795	COG1131	(ABC) transporter
CJO35_04815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO35_04825	COG3382	B3 4 domain protein
CJO35_04830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJO35_04840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CJO35_04845	COG0789	Transcriptional regulator
CJO35_04850	COG1664	Polymer-forming cytoskeletal
CJO35_04860	COG2766	serine protein kinase
CJO35_04865	COG2718	Belongs to the UPF0229 family
CJO35_04870	COG1566	PFAM secretion protein HlyD family protein
CJO35_04875	COG2814	Major facilitator Superfamily
CJO35_04880	COG0655	NAD(P)H dehydrogenase (quinone) activity
CJO35_04900	COG1131	(ABC) transporter
CJO35_04905	COG1131	(ABC) transporter
CJO35_04910	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_04915	COG1278	Cold shock
CJO35_04920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJO35_04925	COG2011	ABC-type metal ion transport system permease component
CJO35_04930	COG1464	Belongs to the NlpA lipoprotein family
CJO35_04935	COG1823	symporter activity
CJO35_04960	COG5577	PFAM Coat F domain
CJO35_04965	COG5002	protein histidine kinase activity
CJO35_04970	COG1525	nuclease
CJO35_04970	COG4085	toxin activity
CJO35_04970	COG0737	Belongs to the 5'-nucleotidase family
CJO35_04975	COG3764	Sortase (surface protein transpeptidase)
CJO35_04980	COG0564	pseudouridine synthase activity
CJO35_04990	COG0517	IMP dehydrogenase activity
CJO35_04995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJO35_05000	COG3153	acetyltransferase
CJO35_05000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO35_05005	COG0488	(ABC) transporter
CJO35_05015	COG2116	formate transmembrane transporter activity
CJO35_05020	COG0679	Auxin Efflux Carrier
CJO35_05025	COG0604	alcohol dehydrogenase
CJO35_05030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CJO35_05035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJO35_05040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJO35_05045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CJO35_05050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJO35_05065	COG2203	Gaf domain
CJO35_05065	COG4585	Histidine kinase
CJO35_05070	COG2197	response regulator
CJO35_05075	COG0431	NADPH-dependent FMN reductase
CJO35_05090	COG1959	2 iron, 2 sulfur cluster binding
CJO35_05095	COG1017	nitric oxide dioxygenase activity
CJO35_05095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CJO35_05100	COG2719	SpoVR family
CJO35_05105	COG0791	NLP P60 protein
CJO35_05105	COG1388	LysM domain
CJO35_05110	COG0583	DNA-binding transcription factor activity
CJO35_05115	COG0372	Belongs to the citrate synthase family
CJO35_05120	COG2133	pyrroloquinoline quinone binding
CJO35_05125	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_05130	COG0733	neurotransmitter:sodium symporter activity
CJO35_05140	COG2207	Transcriptional regulator
CJO35_05140	COG3708	Transcriptional regulator
CJO35_05145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_05165	COG1595	DNA-templated transcription, initiation
CJO35_05170	COG0662	Cupin 2, conserved barrel domain protein
CJO35_05180	COG0204	Acyl-transferase
CJO35_05185	COG3152	Membrane
CJO35_05195	COG1309	transcriptional regulator
CJO35_05200	COG1253	flavin adenine dinucleotide binding
CJO35_05205	COG0789	Transcriptional regulator
CJO35_05210	COG1253	flavin adenine dinucleotide binding
CJO35_05230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJO35_05235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJO35_05240	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_05250	COG0668	transmembrane transport
CJO35_05255	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJO35_05265	COG0726	polysaccharide deacetylase
CJO35_05275	COG1757	Na H antiporter
CJO35_05280	COG2017	converts alpha-aldose to the beta-anomer
CJO35_05305	COG0589	response to stress
CJO35_05310	COG1132	(ABC) transporter
CJO35_05315	COG1132	(ABC) transporter
CJO35_05320	COG0702	epimerase
CJO35_05335	COG3842	ATPase activity
CJO35_05340	COG2508	Transcriptional regulator
CJO35_05350	COG0189	ligase activity
CJO35_05355	COG0189	ligase activity
CJO35_05360	COG4399	Belongs to the UPF0754 family
CJO35_05365	COG3679	Belongs to the UPF0342 family
CJO35_05375	COG0561	phosphatase activity
CJO35_05380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO35_05385	COG0475	glutathione-regulated potassium exporter activity
CJO35_05390	COG0490	domain, Protein
CJO35_05400	COG1024	Enoyl-CoA hydratase
CJO35_05405	COG0457	Tetratricopeptide repeat
CJO35_05420	COG4152	abc transporter atp-binding protein
CJO35_05425	COG1668	transmembrane transport
CJO35_05430	COG0420	3'-5' exonuclease activity
CJO35_05435	COG4717	serine-type aminopeptidase activity
CJO35_05440	COG3481	metal-dependent phosphohydrolase, HD sub domain
CJO35_05450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO35_05480	COG1846	Transcriptional regulator
CJO35_05485	COG4980	gas vesicle protein
CJO35_05500	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJO35_05505	COG0537	adenosine 5'-monophosphoramidase activity
CJO35_05515	COG1131	(ABC) transporter
CJO35_05520	COG4473	ABC transporter
CJO35_05530	COG1473	amidohydrolase
CJO35_05535	COG3069	C4-dicarboxylate transmembrane transporter activity
CJO35_05540	COG2329	Antibiotic biosynthesis monooxygenase
CJO35_05545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_05550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJO35_05565	COG1309	transcriptional regulator
CJO35_05570	COG1511	domain protein
CJO35_05575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO35_05580	COG1363	Peptidase, m42
CJO35_05590	COG1301	dicarboxylic acid transport
CJO35_05600	COG1234	tRNA 3'-trailer cleavage
CJO35_05605	COG0095	Lipoate-protein ligase
CJO35_05610	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_05620	COG1396	sequence-specific DNA binding
CJO35_05635	COG0501	Belongs to the peptidase M48B family
CJO35_05645	COG0697	spore germination
CJO35_05650	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CJO35_05655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_05660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_05665	COG0406	alpha-ribazole phosphatase activity
CJO35_05670	COG0840	transmembrane signaling receptor activity
CJO35_05675	COG0723	plastoquinol--plastocyanin reductase activity
CJO35_05675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO35_05680	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_05690	COG4903	ComK protein
CJO35_05700	COG0398	Pfam SNARE associated Golgi protein
CJO35_05705	COG0681	Belongs to the peptidase S26 family
CJO35_05710	COG1404	Belongs to the peptidase S8 family
CJO35_05720	COG2508	Transcriptional regulator
CJO35_05730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJO35_05740	COG3257	ureidoglycine aminohydrolase activity
CJO35_05745	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CJO35_05750	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CJO35_05755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJO35_05760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJO35_05770	COG0549	Belongs to the carbamate kinase family
CJO35_05775	COG2814	Major facilitator Superfamily
CJO35_05785	COG0457	Tetratricopeptide repeat
CJO35_05825	COG1486	melibiose metabolic process
CJO35_05830	COG3180	Ammonia monooxygenase
CJO35_05845	COG3546	catalase activity
CJO35_05850	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_05855	COG0477	Major facilitator Superfamily
CJO35_05855	COG2814	Major facilitator Superfamily
CJO35_05865	COG5002	protein histidine kinase activity
CJO35_05870	COG0745	RESPONSE REGULATOR receiver
CJO35_05875	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CJO35_05880	COG0725	ABC transporter, periplasmic molybdate-binding protein
CJO35_05885	COG4149	molybdate abc transporter
CJO35_05890	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CJO35_05895	COG1074	ATP-dependent DNA helicase activity
CJO35_05900	COG0420	3'-5' exonuclease activity
CJO35_05905	COG0419	ATPase involved in DNA repair
CJO35_05950	COG5337	Spore coat protein CotH
CJO35_05960	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJO35_05980	COG0367	asparagine synthase
CJO35_05985	COG0004	ammonium transporteR
CJO35_05990	COG0347	Belongs to the P(II) protein family
CJO35_05995	COG0534	Mate efflux family protein
CJO35_06000	COG2207	Transcriptional regulator
CJO35_06000	COG1917	Cupin 2, conserved barrel domain protein
CJO35_06010	COG1609	Transcriptional regulator
CJO35_06015	COG0673	inositol 2-dehydrogenase activity
CJO35_06035	COG1279	arginine transmembrane transporter activity
CJO35_06040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_06050	COG0076	glutamate decarboxylase activity
CJO35_06075	COG2153	protein acetylation
CJO35_06080	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_06085	COG2378	regulation of single-species biofilm formation
CJO35_06090	COG0646	methionine synthase
CJO35_06090	COG1410	methionine synthase
CJO35_06095	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJO35_06095	COG0646	methionine synthase
CJO35_06100	COG1666	GTP binding
CJO35_06105	COG2996	Protein conserved in bacteria
CJO35_06120	COG1307	EDD domain protein, DegV family
CJO35_06125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_06135	COG0516	GMP reductase activity
CJO35_06145	COG0561	phosphatase activity
CJO35_06150	COG1073	alpha beta
CJO35_06155	COG2151	metal-sulfur cluster biosynthetic enzyme
CJO35_06165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJO35_06170	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CJO35_06175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJO35_06180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO35_06185	COG0505	Belongs to the CarA family
CJO35_06190	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJO35_06195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJO35_06200	COG1968	undecaprenyl-diphosphatase activity
CJO35_06215	COG2267	carboxylic ester hydrolase activity
CJO35_06225	COG1744	ABC transporter substrate-binding protein PnrA-like
CJO35_06240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO35_06245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO35_06250	COG5504	Zn-dependent protease
CJO35_06255	COG0444	Belongs to the ABC transporter superfamily
CJO35_06260	COG4608	Belongs to the ABC transporter superfamily
CJO35_06270	COG0601	transmembrane transport
CJO35_06275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_06300	COG0180	Tryptophanyl-tRNA synthetase
CJO35_06310	COG4166	transmembrane transport
CJO35_06315	COG0601	transmembrane transport
CJO35_06320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_06325	COG0444	Belongs to the ABC transporter superfamily
CJO35_06330	COG4608	Belongs to the ABC transporter superfamily
CJO35_06335	COG0456	acetyltransferase
CJO35_06340	COG1393	Belongs to the ArsC family
CJO35_06345	COG0861	Integral membrane protein TerC family
CJO35_06350	COG4862	establishment of competence for transformation
CJO35_06370	COG4565	transcriptional regulatory protein
CJO35_06375	COG3290	protein histidine kinase activity
CJO35_06380	COG4469	Competence protein
CJO35_06385	COG1164	Oligoendopeptidase f
CJO35_06400	COG2346	COG2346, Truncated hemoglobins
CJO35_06405	COG0741	lytic transglycosylase activity
CJO35_06410	COG4116	CYTH
CJO35_06420	COG2357	RelA SpoT domain protein
CJO35_06425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJO35_06430	COG0564	pseudouridine synthase activity
CJO35_06435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CJO35_06445	COG0475	glutathione-regulated potassium exporter activity
CJO35_06445	COG0569	domain protein
CJO35_06450	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJO35_06455	COG0352	thiamine-phosphate diphosphorylase activity
CJO35_06465	COG2104	thiamine diphosphate biosynthetic process
CJO35_06470	COG2022	thiamine diphosphate biosynthetic process
CJO35_06475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CJO35_06480	COG0351	phosphomethylpyrimidine kinase
CJO35_06485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CJO35_06540	COG0210	DNA helicase
CJO35_06550	COG0586	Pfam SNARE associated Golgi protein
CJO35_06555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_06560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CJO35_06565	COG2246	polysaccharide biosynthetic process
CJO35_06570	COG2153	protein acetylation
CJO35_06575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CJO35_06580	COG2382	esterase
CJO35_06600	COG0626	cystathionine gamma-synthase activity
CJO35_06605	COG0626	cystathionine gamma-synthase activity
CJO35_06630	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_06650	COG0110	maltose O-acetyltransferase activity
CJO35_06660	COG0583	DNA-binding transcription factor activity
CJO35_06665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CJO35_06670	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CJO35_06675	COG0583	DNA-binding transcription factor activity
CJO35_06680	COG0697	spore germination
CJO35_06685	COG0346	lactoylglutathione lyase activity
CJO35_06695	COG3584	3D domain protein
CJO35_06695	COG1388	LysM domain
CJO35_06700	COG2814	Major facilitator Superfamily
CJO35_06705	COG1309	transcriptional regulator
CJO35_06730	COG4195	phage-related replication protein
CJO35_06735	COG2856	Zn peptidase
CJO35_06740	COG1396	sequence-specific DNA binding
CJO35_06755	COG1522	sequence-specific DNA binding
CJO35_06760	COG1484	DNA-dependent DNA replication
CJO35_06775	COG1595	DNA-templated transcription, initiation
CJO35_06780	COG5484	DNA packaging
CJO35_06780	COG3728	DNA packaging
CJO35_06785	COG1783	phage Terminase large subunit
CJO35_06790	COG5518	Phage portal protein
CJO35_06795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CJO35_06800	COG4653	Phage capsid family
CJO35_06855	COG1652	LysM domain
CJO35_06860	COG4193	domain, Protein
CJO35_06870	COG3628	GPW Gp25 family protein
CJO35_06875	COG3299	homolog of phage Mu protein gp47
CJO35_06880	COG3778	Protein conserved in bacteria
CJO35_06915	COG1802	Transcriptional regulator
CJO35_06920	COG1063	alcohol dehydrogenase
CJO35_06925	COG1312	Catalyzes the dehydration of D-mannonate
CJO35_06930	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_06935	COG1063	alcohol dehydrogenase
CJO35_06940	COG2271	Major facilitator Superfamily
CJO35_06955	COG0306	phosphate transporter
CJO35_06960	COG1392	Phosphate transport regulator
CJO35_06965	COG0405	Gamma-glutamyltransferase
CJO35_06970	COG5578	integral membrane protein
CJO35_06975	COG2972	Histidine kinase
CJO35_06980	COG4753	response regulator
CJO35_06980	COG2207	Transcriptional regulator
CJO35_06985	COG1653	transport
CJO35_06990	COG1175	transmembrane transport
CJO35_06995	COG0395	ABC-type sugar transport system, permease component
CJO35_07000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJO35_07005	COG2207	Transcriptional regulator
CJO35_07010	COG2755	lipolytic protein G-D-S-L family
CJO35_07020	COG5578	integral membrane protein
CJO35_07025	COG3401	FG-GAP repeat protein
CJO35_07035	COG2755	lipolytic protein G-D-S-L family
CJO35_07040	COG3401	FG-GAP repeat protein
CJO35_07045	COG0667	Aldo Keto reductase
CJO35_07050	COG2755	lipolytic protein G-D-S-L family
CJO35_07055	COG1874	Beta-galactosidase
CJO35_07065	COG1653	transport
CJO35_07070	COG4209	transmembrane transport
CJO35_07075	COG0395	ABC-type sugar transport system, permease component
CJO35_07080	COG0531	amino acid
CJO35_07085	COG0346	lactoylglutathione lyase activity
CJO35_07095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_07100	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJO35_07105	COG2362	D-Aminopeptidase
CJO35_07110	COG0601	transmembrane transport
CJO35_07115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJO35_07120	COG0444	Belongs to the ABC transporter superfamily
CJO35_07125	COG4166	transmembrane transport
CJO35_07130	COG1619	proteins homologs of microcin C7 resistance protein MccF
CJO35_07135	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_07140	COG0791	NLP P60 protein
CJO35_07145	COG4608	Belongs to the ABC transporter superfamily
CJO35_07150	COG1834	amidinotransferase
CJO35_07155	COG1607	acyl-coa hydrolase
CJO35_07190	COG2076	Multidrug Resistance protein
CJO35_07195	COG2076	Multidrug Resistance protein
CJO35_07200	COG0788	formyltetrahydrofolate deformylase activity
CJO35_07205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJO35_07210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJO35_07215	COG1764	response to oxidative stress
CJO35_07220	COG1846	Transcriptional regulator
CJO35_07225	COG1764	response to oxidative stress
CJO35_07235	COG0590	tRNA wobble adenosine to inosine editing
CJO35_07240	COG0406	alpha-ribazole phosphatase activity
CJO35_07255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CJO35_07260	COG1404	Belongs to the peptidase S8 family
CJO35_07270	COG2239	Acts as a magnesium transporter
CJO35_07285	COG2856	Zn peptidase
CJO35_07295	COG3620	sequence-specific DNA binding
CJO35_07345	COG3935	DnaD domain protein
CJO35_07350	COG1484	DNA-dependent DNA replication
CJO35_07440	COG3677	Transposase
CJO35_07450	COG5484	DNA packaging
CJO35_07455	COG1783	phage Terminase large subunit
CJO35_07575	COG0662	Cupin 2, conserved barrel domain protein
CJO35_07580	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CJO35_07585	COG2323	membrane
CJO35_07590	COG0789	Transcriptional regulator
CJO35_07605	COG1846	Transcriptional regulator
CJO35_07610	COG1793	dna ligase
CJO35_07610	COG3285	dna ligase
CJO35_07615	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CJO35_07620	COG3300	MHYT domain
CJO35_07620	COG5001	Diguanylate cyclase
CJO35_07625	COG0586	Pfam SNARE associated Golgi protein
CJO35_07630	COG0861	Integral membrane protein TerC family
CJO35_07635	COG1191	sigma factor activity
CJO35_07655	COG0501	Belongs to the peptidase M48B family
CJO35_07660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJO35_07665	COG0768	penicillin binding
CJO35_07680	COG3594	Acyltransferase
CJO35_07685	COG5002	protein histidine kinase activity
CJO35_07690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO35_07700	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CJO35_07705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO35_07710	COG0436	Aminotransferase
CJO35_07715	COG1850	ribulose-bisphosphate carboxylase activity
CJO35_07720	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CJO35_07720	COG0235	Class ii aldolase
CJO35_07725	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CJO35_07730	COG0346	lactoylglutathione lyase activity
CJO35_07735	COG3339	Conserved Protein
CJO35_07745	COG3852	Histidine kinase
CJO35_07750	COG1846	Transcriptional regulator
CJO35_07755	COG1360	Flagellar Motor Protein
CJO35_07760	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CJO35_07765	COG0542	response to heat
CJO35_07770	COG3949	Membrane
CJO35_07775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CJO35_07780	COG0720	synthase
CJO35_07785	COG0602	queuosine metabolic process
CJO35_07790	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJO35_07800	COG3739	integral membrane protein
CJO35_07805	COG3655	Transcriptional regulator
CJO35_07835	COG4873	Protein conserved in bacteria
CJO35_07845	COG3773	Cell wall hydrolase
CJO35_07850	COG2244	polysaccharide biosynthetic process
CJO35_07855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_07860	COG2217	Heavy metal translocating P-type atpase
CJO35_07865	COG0006	proline dipeptidase activity
CJO35_07875	COG1609	Transcriptional regulator
CJO35_07880	COG3711	transcriptional antiterminator
CJO35_07885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_07885	COG2190	(PTS) system
CJO35_07885	COG1263	PTS System
CJO35_07890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_07895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJO35_07905	COG1533	DNA photolyase activity
CJO35_07910	COG0456	acetyltransferase
CJO35_07915	COG0840	transmembrane signaling receptor activity
CJO35_07920	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_07925	COG2084	Dehydrogenase
CJO35_07930	COG2340	Cysteine-rich secretory protein family
CJO35_07935	COG0768	penicillin binding
CJO35_07940	COG4191	Histidine kinase
CJO35_07945	COG0436	Aminotransferase
CJO35_07950	COG1714	RDD family
CJO35_07960	COG0835	chemotaxis
CJO35_07960	COG0784	Response regulator, receiver
CJO35_07970	COG2814	Major facilitator Superfamily
CJO35_07975	COG1376	ErfK ybiS ycfS ynhG family protein
CJO35_07985	COG1408	metallophosphoesterase
CJO35_07990	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_07995	COG2200	EAL domain
CJO35_08005	COG4703	Protein of unknown function (DUF1797)
CJO35_08015	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CJO35_08025	COG0517	IMP dehydrogenase activity
CJO35_08030	COG0583	DNA-binding transcription factor activity
CJO35_08035	COG0716	FMN binding
CJO35_08045	COG0716	FMN binding
CJO35_08050	COG2171	N-acyltransferase activity
CJO35_08055	COG1473	amidohydrolase
CJO35_08065	COG0450	alkyl hydroperoxide reductase
CJO35_08070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_08085	COG0746	molybdenum cofactor guanylyltransferase activity
CJO35_08090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CJO35_08095	COG0303	'Molybdopterin
CJO35_08100	COG1763	Mo-molybdopterin cofactor biosynthetic process
CJO35_08105	COG0314	molybdopterin synthase activity
CJO35_08110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CJO35_08120	COG1132	(ABC) transporter
CJO35_08125	COG1132	(ABC) transporter
CJO35_08135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO35_08140	COG1136	(ABC) transporter
CJO35_08145	COG0577	efflux transmembrane transporter activity
CJO35_08150	COG1349	DNA-binding transcription factor activity
CJO35_08155	COG1105	Belongs to the carbohydrate kinase PfkB family
CJO35_08160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_08160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_08160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_08180	COG0488	(ABC) transporter
CJO35_08190	COG2309	aminopeptidase activity
CJO35_08200	COG1077	Cell shape determining protein MreB Mrl
CJO35_08205	COG2002	toxin-antitoxin pair type II binding
CJO35_08210	COG3852	Histidine kinase
CJO35_08215	COG0569	domain protein
CJO35_08220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJO35_08225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CJO35_08235	COG0561	phosphatase activity
CJO35_08245	COG0242	peptide deformylase activity
CJO35_08255	COG0497	DNA recombination
CJO35_08260	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO35_08265	COG0022	dehydrogenase e1 component
CJO35_08270	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_08275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO35_08280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_08290	COG1982	Orn Lys Arg decarboxylase major
CJO35_08295	COG4476	Belongs to the UPF0223 family
CJO35_08300	COG4493	Belongs to the UPF0637 family
CJO35_08310	COG0483	inositol monophosphate 1-phosphatase activity
CJO35_08330	COG1595	DNA-templated transcription, initiation
CJO35_08355	COG1846	Transcriptional regulator
CJO35_08360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO35_08365	COG4896	Protein conserved in bacteria
CJO35_08375	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CJO35_08380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO35_08385	COG2066	Belongs to the glutaminase family
CJO35_08390	COG4838	Belongs to the UPF0358 family
CJO35_08395	COG0772	Belongs to the SEDS family
CJO35_08400	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CJO35_08405	COG1612	heme a metabolic process
CJO35_08410	COG0109	protoheme IX farnesyltransferase activity
CJO35_08415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO35_08415	COG2010	Cytochrome c
CJO35_08420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO35_08425	COG1845	cytochrome c oxidase, subunit III
CJO35_08430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CJO35_08435	COG3336	cytochrome c oxidase
CJO35_08445	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CJO35_08450	COG2340	Cysteine-rich secretory protein family
CJO35_08465	COG3679	Belongs to the UPF0342 family
CJO35_08470	COG4471	UPF0298 protein
CJO35_08475	COG0742	ribosomal rna small subunit methyltransferase
CJO35_08480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJO35_08485	COG3314	Sporulation integral membrane protein YlbJ
CJO35_08490	COG3480	Lon protease (S16) C-terminal proteolytic domain
CJO35_08495	COG1323	Belongs to the UPF0348 family
CJO35_08500	COG1399	metal-binding, possibly nucleic acid-binding protein
CJO35_08505	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJO35_08515	COG0454	-acetyltransferase
CJO35_08520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJO35_08525	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CJO35_08530	COG2001	Belongs to the MraZ family
CJO35_08535	COG0275	rRNA processing
CJO35_08540	COG4839	cell division protein FtsL
CJO35_08550	COG0768	penicillin binding
CJO35_08555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJO35_08560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO35_08565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJO35_08570	COG0772	Belongs to the SEDS family
CJO35_08575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_08580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJO35_08585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CJO35_08590	COG3879	Bacterial protein of unknown function (DUF881)
CJO35_08595	COG3879	Bacterial protein of unknown function (DUF881)
CJO35_08600	COG3856	small basic protein
CJO35_08605	COG0849	cell division
CJO35_08610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CJO35_08615	COG1404	Belongs to the peptidase S8 family
CJO35_08615	COG4412	M6 family metalloprotease domain protein
CJO35_08620	COG4412	M6 family metalloprotease domain protein
CJO35_08620	COG1404	Belongs to the peptidase S8 family
CJO35_08630	COG1191	sigma factor activity
CJO35_08635	COG1191	sigma factor activity
CJO35_08640	COG1119	ATPase activity
CJO35_08645	COG0500	methyltransferase
CJO35_08650	COG1873	PFAM PRC-barrel domain
CJO35_08660	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CJO35_08665	COG1799	cell septum assembly
CJO35_08670	COG0762	integral membrane protein
CJO35_08675	COG2302	S4 RNA-binding domain
CJO35_08680	COG3599	regulation of cell shape
CJO35_08685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJO35_08690	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJO35_08695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJO35_08700	COG0564	pseudouridine synthase activity
CJO35_08705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CJO35_08710	COG2233	PERMEase
CJO35_08715	COG0540	Belongs to the ATCase OTCase family
CJO35_08720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJO35_08725	COG0505	Belongs to the CarA family
CJO35_08730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CJO35_08735	COG0543	2 iron, 2 sulfur cluster binding
CJO35_08740	COG0167	dihydroorotate dehydrogenase activity
CJO35_08745	COG0284	orotidine-5'-phosphate decarboxylase activity
CJO35_08750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJO35_08760	COG0175	sulfate reduction
CJO35_08765	COG0306	phosphate transporter
CJO35_08770	COG2046	Belongs to the sulfate adenylyltransferase family
CJO35_08775	COG0529	Catalyzes the synthesis of activated sulfate
CJO35_08780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJO35_08785	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CJO35_08790	COG1648	precorrin-2 dehydrogenase activity
CJO35_08800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CJO35_08805	COG1561	YicC-like family, N-terminal region
CJO35_08810	COG2052	Domain of unknown function (DUF370)
CJO35_08815	COG0194	GDP metabolic process
CJO35_08820	COG1758	RNA polymerase activity
CJO35_08825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJO35_08830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CJO35_08835	COG0242	peptide deformylase activity
CJO35_08840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJO35_08845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO35_08845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CJO35_08850	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJO35_08855	COG0631	protein serine/threonine phosphatase activity
CJO35_08860	COG0515	serine threonine protein kinase
CJO35_08860	COG2815	serine threonine protein kinase
CJO35_08865	COG1162	GTPase activity
CJO35_08870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJO35_08875	COG1564	THIamine pyrophosphokinase
CJO35_08885	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJO35_08890	COG1302	Protein conserved in bacteria
CJO35_08895	COG1461	Dihydroxyacetone kinase
CJO35_08900	COG1760	l-serine dehydratase
CJO35_08905	COG1760	l-serine dehydratase
CJO35_08910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJO35_08915	COG1349	DNA-binding transcription factor activity
CJO35_08920	COG0416	fatty acid biosynthetic process
CJO35_08925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CJO35_08930	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_08935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO35_08940	COG0571	ribonuclease III activity
CJO35_08945	COG1196	nuclear chromosome segregation
CJO35_08950	COG0552	protein localization to endoplasmic reticulum
CJO35_08955	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CJO35_08960	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJO35_08965	COG0228	four-way junction DNA binding
CJO35_08970	COG1837	Belongs to the UPF0109 family
CJO35_08980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJO35_08985	COG0336	Belongs to the RNA methyltransferase TrmD family
CJO35_08990	COG0335	large ribosomal subunit rRNA binding
CJO35_08995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CJO35_09000	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJO35_09010	COG2257	FlhB HrpN YscU SpaS Family
CJO35_09015	COG0045	succinate-CoA ligase (ADP-forming) activity
CJO35_09020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJO35_09025	COG0758	DNA mediated transformation
CJO35_09030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJO35_09035	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CJO35_09040	COG4974	Belongs to the 'phage' integrase family
CJO35_09045	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CJO35_09050	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CJO35_09055	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CJO35_09060	COG1815	bacterial-type flagellum-dependent cell motility
CJO35_09065	COG1558	bacterial-type flagellum-dependent cell motility
CJO35_09070	COG1677	Flagellar hook-basal body complex protein FliE
CJO35_09075	COG1766	The M ring may be actively involved in energy transduction
CJO35_09080	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO35_09085	COG1317	bacterial-type flagellum organization
CJO35_09090	COG1157	protein secretion by the type III secretion system
CJO35_09095	COG2882	bacterial-type flagellum organization
CJO35_09105	COG3144	bacterial-type flagellum assembly
CJO35_09110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CJO35_09115	COG4786	Flagellar basal body rod
CJO35_09120	COG1582	Flagellar protein (FlbD)
CJO35_09125	COG1580	Controls the rotational direction of flagella during chemotaxis
CJO35_09130	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO35_09135	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CJO35_09135	COG1776	CheC inhibitor of MCP methylation
CJO35_09140	COG2201	protein-glutamate methylesterase activity
CJO35_09145	COG3190	flagellar
CJO35_09150	COG1338	Plays a role in the flagellum-specific transport system
CJO35_09155	COG1987	bacterial-type flagellum assembly
CJO35_09160	COG1684	flagellar biosynthetic protein fliR
CJO35_09165	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO35_09170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CJO35_09175	COG1419	protein localization to endoplasmic reticulum
CJO35_09180	COG0455	bacterial-type flagellum organization
CJO35_09185	COG2201	protein-glutamate methylesterase activity
CJO35_09190	COG0643	Histidine kinase
CJO35_09190	COG2198	Histidine kinase
CJO35_09195	COG0835	chemotaxis
CJO35_09200	COG1776	CheC inhibitor of MCP methylation
CJO35_09205	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CJO35_09210	COG1191	sigma factor activity
CJO35_09220	COG0052	Belongs to the universal ribosomal protein uS2 family
CJO35_09225	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJO35_09230	COG0528	UMP kinase activity
CJO35_09235	COG0233	cytoplasmic translational termination
CJO35_09240	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CJO35_09245	COG4589	Belongs to the CDS family
CJO35_09250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CJO35_09255	COG0750	zinc metalloprotease
CJO35_09260	COG0442	prolyl-tRNA aminoacylation
CJO35_09265	COG2176	DNA-directed DNA polymerase activity
CJO35_09295	COG0779	Required for maturation of 30S ribosomal subunits
CJO35_09300	COG0195	Participates in both transcription termination and antitermination
CJO35_09305	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CJO35_09310	COG1358	cellular component organization or biogenesis
CJO35_09315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJO35_09320	COG1550	Protein conserved in bacteria
CJO35_09325	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJO35_09330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJO35_09335	COG0196	riboflavin kinase activity
CJO35_09340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJO35_09345	COG1185	polyribonucleotide nucleotidyltransferase activity
CJO35_09350	COG0726	polysaccharide deacetylase
CJO35_09355	COG0612	Peptidase, M16
CJO35_09360	COG1873	PFAM PRC-barrel domain
CJO35_09365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO35_09370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJO35_09375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CJO35_09380	COG0527	aspartate kinase activity
CJO35_09390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CJO35_09395	COG0740	serine-type endopeptidase activity
CJO35_09405	COG4980	gas vesicle protein
CJO35_09405	COG1674	ftsk spoiiie
CJO35_09410	COG2188	Transcriptional regulator
CJO35_09415	COG2814	Major facilitator Superfamily
CJO35_09420	COG0612	Peptidase, M16
CJO35_09425	COG0612	Peptidase, M16
CJO35_09430	COG0300	oxidoreductase activity
CJO35_09445	COG1426	Protein conserved in bacteria
CJO35_09450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CJO35_09455	COG1546	Belongs to the CinA family
CJO35_09455	COG1058	Belongs to the CinA family
CJO35_09460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CJO35_09465	COG1418	mRNA catabolic process
CJO35_09470	COG1692	metallophosphoesterase
CJO35_09475	COG2359	stage V sporulation protein S
CJO35_09485	COG1063	alcohol dehydrogenase
CJO35_09490	COG0156	8-amino-7-oxononanoate synthase activity
CJO35_09495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO35_09500	COG4550	Control of competence regulator ComK, YlbF/YmcA
CJO35_09510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJO35_09515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJO35_09520	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CJO35_09525	COG5444	nuclease activity
CJO35_09545	COG0523	cobalamin synthesis protein
CJO35_09555	COG1247	-acetyltransferase
CJO35_09575	COG3619	membrane
CJO35_09580	COG3263	regulation of cellular component size
CJO35_09585	COG2814	Major facilitator Superfamily
CJO35_09590	COG2814	Major facilitator Superfamily
CJO35_09595	COG2814	Major facilitator Superfamily
CJO35_09600	COG2267	carboxylic ester hydrolase activity
CJO35_09605	COG2267	carboxylic ester hydrolase activity
CJO35_09615	COG0393	Putative heavy-metal-binding
CJO35_09620	COG0398	Pfam SNARE associated Golgi protein
CJO35_09625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CJO35_09630	COG1819	glycosyl
CJO35_09635	COG0531	amino acid
CJO35_09640	COG5577	PFAM Coat F domain
CJO35_09650	COG1388	LysM domain
CJO35_09650	COG3858	chitin binding
CJO35_09655	COG1309	transcriptional regulator
CJO35_09660	COG3631	Ketosteroid isomerase-related protein
CJO35_09665	COG0702	epimerase
CJO35_09675	COG1764	response to oxidative stress
CJO35_09680	COG2076	Multidrug Resistance protein
CJO35_09685	COG2076	Multidrug Resistance protein
CJO35_09700	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJO35_09705	COG1923	regulation of RNA biosynthetic process
CJO35_09720	COG1780	Probably involved in ribonucleotide reductase function
CJO35_09725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJO35_09730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJO35_09735	COG4112	unkown
CJO35_09750	COG0735	belongs to the Fur family
CJO35_09755	COG1802	Transcriptional regulator
CJO35_09760	COG0697	spore germination
CJO35_09795	COG1309	transcriptional regulator
CJO35_09850	COG0464	growth
CJO35_09855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJO35_09860	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CJO35_09865	COG0789	Transcriptional regulator
CJO35_09870	COG0174	glutamine synthetase
CJO35_09915	COG1073	alpha beta
CJO35_09955	COG1309	transcriptional regulator
CJO35_09960	COG2076	Multidrug Resistance protein
CJO35_09965	COG2076	Multidrug Resistance protein
CJO35_09970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_09985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_09990	COG3546	catalase activity
CJO35_10015	COG1846	Transcriptional regulator
CJO35_10020	COG0778	Nitroreductase
CJO35_10025	COG0346	lactoylglutathione lyase activity
CJO35_10030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO35_10035	COG0655	NAD(P)H dehydrogenase (quinone) activity
CJO35_10050	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CJO35_10055	COG3209	COG3209 Rhs family protein
CJO35_10060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJO35_10065	COG1388	LysM domain
CJO35_10070	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CJO35_10075	COG4224	UPF0291 protein
CJO35_10080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CJO35_10090	COG3763	UPF0154 protein
CJO35_10100	COG0785	Cytochrome C biogenesis protein
CJO35_10105	COG2201	protein-glutamate methylesterase activity
CJO35_10110	COG4846	Membrane protein involved in cytochrome C biogenesis
CJO35_10120	COG0071	Belongs to the small heat shock protein (HSP20) family
CJO35_10135	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJO35_10140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_10160	COG0824	Thioesterase
CJO35_10185	COG4841	protein insertion into membrane
CJO35_10190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CJO35_10195	COG1832	CoA-binding protein
CJO35_10200	COG0187	DNA topoisomerase II activity
CJO35_10205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJO35_10210	COG1609	Transcriptional regulator
CJO35_10225	COG2160	L-arabinose isomerase activity
CJO35_10245	COG1115	amino acid carrier protein
CJO35_10255	COG2181	nitrate reductase activity
CJO35_10260	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CJO35_10265	COG1140	nitrate reductase beta subunit
CJO35_10270	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CJO35_10290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO35_10300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO35_10305	COG2223	nitrite transmembrane transporter activity
CJO35_10325	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CJO35_10335	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
CJO35_10345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_10370	COG3420	alginic acid biosynthetic process
CJO35_10375	COG1114	Component of the transport system for branched-chain amino acids
CJO35_10385	COG0789	Transcriptional regulator
CJO35_10410	COG1024	Enoyl-CoA hydratase
CJO35_10415	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_10420	COG2084	Dehydrogenase
CJO35_10425	COG1960	acyl-CoA dehydrogenase activity
CJO35_10430	COG1482	cell wall glycoprotein biosynthetic process
CJO35_10435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_10435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_10435	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_10455	COG3711	transcriptional antiterminator
CJO35_10455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_10470	COG1725	Transcriptional regulator
CJO35_10475	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_10480	COG1312	Catalyzes the dehydration of D-mannonate
CJO35_10495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CJO35_10505	COG1609	Transcriptional regulator
CJO35_10510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO35_10515	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CJO35_10520	COG0640	Transcriptional regulator
CJO35_10530	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CJO35_10545	COG1649	PFAM Uncharacterised BCR, COG1649
CJO35_10550	COG2404	hydrolase activity, acting on ester bonds
CJO35_10555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CJO35_10565	COG2027	D-alanyl-D-alanine carboxypeptidase
CJO35_10570	COG1252	NADH dehydrogenase
CJO35_10585	COG0166	Belongs to the GPI family
CJO35_10595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO35_10600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO35_10605	COG1024	Enoyl-CoA hydratase
CJO35_10610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO35_10615	COG0511	ligase activity, forming carbon-carbon bonds
CJO35_10620	COG0439	Biotin carboxylase
CJO35_10625	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_10630	COG1960	acyl-CoA dehydrogenase activity
CJO35_10635	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJO35_10640	COG1733	regulation of RNA biosynthetic process
CJO35_10645	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJO35_10650	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJO35_10660	COG2323	membrane
CJO35_10670	COG0306	phosphate transporter
CJO35_10675	COG0175	sulfate reduction
CJO35_10680	COG1809	phosphosulfolactate synthase activity
CJO35_10685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_10690	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_10695	COG2814	Major facilitator Superfamily
CJO35_10700	COG0463	Glycosyl transferase, family 2
CJO35_10715	COG0493	'glutamate synthase
CJO35_10720	COG0069	glutamate synthase activity
CJO35_10720	COG0067	glutamate synthase
CJO35_10720	COG0070	glutamate synthase
CJO35_10725	COG0583	DNA-binding transcription factor activity
CJO35_10745	COG1846	Transcriptional regulator
CJO35_10755	COG1132	(ABC) transporter
CJO35_10765	COG0300	oxidoreductase activity
CJO35_10770	COG0574	Belongs to the PEP-utilizing enzyme family
CJO35_10770	COG3848	Pyruvate phosphate dikinase
CJO35_10780	COG0477	Major facilitator Superfamily
CJO35_10785	COG0243	molybdopterin cofactor binding
CJO35_10790	COG1846	Transcriptional regulator
CJO35_10800	COG0531	amino acid
CJO35_10810	COG0531	amino acid
CJO35_10815	COG0531	amino acid
CJO35_10820	COG0697	spore germination
CJO35_10835	COG0840	transmembrane signaling receptor activity
CJO35_10840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_10845	COG1404	Belongs to the peptidase S8 family
CJO35_10855	COG1309	transcriptional regulator
CJO35_10860	COG1846	Transcriptional regulator
CJO35_10890	COG1309	transcriptional regulator
CJO35_10910	COG2378	regulation of single-species biofilm formation
CJO35_10920	COG0640	Transcriptional regulator
CJO35_10925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_10935	COG0531	amino acid
CJO35_10940	COG0741	lytic transglycosylase activity
CJO35_10945	COG1086	Polysaccharide biosynthesis protein
CJO35_10965	COG2322	membrane
CJO35_10980	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_10985	COG1388	LysM domain
CJO35_10985	COG3584	3D domain protein
CJO35_10990	COG0514	ATP-dependent DNA helicase (RecQ)
CJO35_11030	COG2427	Protein of unknown function (DUF1641)
CJO35_11035	COG3383	formate dehydrogenase (NAD+) activity
CJO35_11060	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CJO35_11105	COG0402	S-adenosylhomocysteine deaminase activity
CJO35_11120	COG2267	carboxylic ester hydrolase activity
CJO35_11135	COG1280	lysine exporter protein (LysE YggA)
CJO35_11140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO35_11150	COG3848	Pyruvate phosphate dikinase
CJO35_11150	COG0574	Belongs to the PEP-utilizing enzyme family
CJO35_11155	COG1309	transcriptional regulator
CJO35_11170	COG2318	DinB family
CJO35_11175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJO35_11180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJO35_11195	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_11200	COG2814	Major facilitator Superfamily
CJO35_11215	COG1657	PFAM Prenyltransferase squalene oxidase
CJO35_11220	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJO35_11230	COG0733	neurotransmitter:sodium symporter activity
CJO35_11235	COG0385	Bile acid
CJO35_11240	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_11245	COG0567	Dehydrogenase, E1 component
CJO35_11250	COG4548	von Willebrand factor, type A
CJO35_11255	COG0714	Associated with various cellular activities
CJO35_11260	COG2032	superoxide dismutase activity
CJO35_11265	COG0791	NLP P60 protein
CJO35_11265	COG1388	LysM domain
CJO35_11275	COG0534	Mate efflux family protein
CJO35_11280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJO35_11285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJO35_11295	COG2962	Rard protein
CJO35_11305	COG4305	rare lipoprotein A
CJO35_11320	COG1733	regulation of RNA biosynthetic process
CJO35_11325	COG0778	Nitroreductase
CJO35_11330	COG0400	carboxylic ester hydrolase activity
CJO35_11340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_11345	COG3409	Peptidoglycan-binding domain 1 protein
CJO35_11345	COG0793	Belongs to the peptidase S41A family
CJO35_11350	COG2226	methyltransferase
CJO35_11360	COG1876	peptidase activity
CJO35_11365	COG0813	purine-nucleoside phosphorylase activity
CJO35_11370	COG0701	Predicted permease
CJO35_11390	COG0671	phosphoesterase, PA-phosphatase related
CJO35_11410	COG4479	Belongs to the UPF0346 family
CJO35_11420	COG1509	lysine 2,3-aminomutase activity
CJO35_11425	COG0456	acetyltransferase
CJO35_11430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO35_11435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CJO35_11440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CJO35_11445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CJO35_11460	COG0456	acetyltransferase
CJO35_11465	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO35_11470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO35_11475	COG1846	Transcriptional regulator
CJO35_11485	COG3706	GGDEF domain
CJO35_11490	COG0534	Mate efflux family protein
CJO35_11505	COG4698	Protein conserved in bacteria
CJO35_11510	COG2755	lipolytic protein G-D-S-L family
CJO35_11515	COG1999	signal sequence binding
CJO35_11530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJO35_11535	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CJO35_11540	COG1272	protein, Hemolysin III
CJO35_11545	COG0204	Acyl-transferase
CJO35_11550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJO35_11555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CJO35_11565	COG2136	Putative SAM-dependent methyltransferase
CJO35_11565	COG2521	methyltransferase
CJO35_11575	COG0129	dihydroxy-acid dehydratase activity
CJO35_11580	COG1413	lyase activity
CJO35_11585	COG1418	mRNA catabolic process
CJO35_11590	COG0386	Belongs to the glutathione peroxidase family
CJO35_11595	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CJO35_11600	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CJO35_11605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_11615	COG1278	Cold shock
CJO35_11635	COG0328	RNA-DNA hybrid ribonuclease activity
CJO35_11640	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CJO35_11645	COG0328	RNA-DNA hybrid ribonuclease activity
CJO35_11655	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO35_11670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CJO35_11680	COG1755	Isoprenylcysteine carboxyl methyltransferase
CJO35_11685	COG3424	synthase
CJO35_11690	COG0456	acetyltransferase
CJO35_11695	COG2233	PERMEase
CJO35_11700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO35_11705	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CJO35_11710	COG1199	ATP-dependent helicase activity
CJO35_11725	COG0116	Belongs to the methyltransferase superfamily
CJO35_11735	COG3599	regulation of cell shape
CJO35_11740	COG4474	Belongs to the UPF0398 family
CJO35_11750	COG3359	exonuclease
CJO35_11755	COG1111	helicase
CJO35_11755	COG1205	dead DEAH box helicase
CJO35_11760	COG2190	(PTS) system
CJO35_11765	COG0071	Belongs to the small heat shock protein (HSP20) family
CJO35_11800	COG3331	DNA recombination
CJO35_11805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_11805	COG4499	WXG100 protein secretion system (Wss), protein YukC
CJO35_11815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CJO35_11820	COG3935	DnaD domain protein
CJO35_11825	COG0017	Asparaginyl-tRNA synthetase
CJO35_11830	COG0436	Aminotransferase
CJO35_11835	COG5353	protein conserved in bacteria
CJO35_11845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJO35_11845	COG1199	ATP-dependent helicase activity
CJO35_11850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CJO35_11855	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJO35_11860	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJO35_11875	COG0617	tRNA 3'-terminal CCA addition
CJO35_11880	COG0438	transferase activity, transferring glycosyl groups
CJO35_11885	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CJO35_11890	COG1803	Methylglyoxal synthase
CJO35_11895	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJO35_11900	COG1694	Mazg nucleotide pyrophosphohydrolase
CJO35_11905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_11915	COG4347	Protein of unknown function (DUF1405)
CJO35_11920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJO35_11920	COG2010	Cytochrome c
CJO35_11925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJO35_11930	COG0723	plastoquinol--plastocyanin reductase activity
CJO35_11940	COG5582	Belongs to the UPF0302 family
CJO35_11945	COG0457	Tetratricopeptide repeat
CJO35_11950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJO35_11955	COG0287	Prephenate dehydrogenase
CJO35_11960	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJO35_11965	COG0159	tryptophan synthase activity
CJO35_11970	COG0133	tryptophan synthase activity
CJO35_11975	COG0135	phosphoribosylanthranilate isomerase activity
CJO35_11980	COG0134	indole-3-glycerol-phosphate synthase activity
CJO35_11985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO35_11990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJO35_11995	COG4401	Chorismate mutase type I
CJO35_12000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJO35_12005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJO35_12010	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CJO35_12015	COG0105	UTP biosynthetic process
CJO35_12020	COG0142	geranyltranstransferase activity
CJO35_12025	COG2226	methyltransferase
CJO35_12030	COG0142	geranyltranstransferase activity
CJO35_12045	COG0776	regulation of translation
CJO35_12050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CJO35_12070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJO35_12075	COG1160	GTP binding
CJO35_12100	COG1304	FMN binding
CJO35_12105	COG0539	negative regulation of cytoplasmic translation
CJO35_12110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CJO35_12120	COG2959	enzyme of heme biosynthesis
CJO35_12125	COG3409	Peptidoglycan-binding domain 1 protein
CJO35_12125	COG3773	Cell wall hydrolase
CJO35_12130	COG2339	peptidase activity
CJO35_12140	COG0492	ferredoxin-NADP+ reductase activity
CJO35_12145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJO35_12150	COG4862	establishment of competence for transformation
CJO35_12155	COG1408	metallophosphoesterase
CJO35_12165	COG1388	LysM domain
CJO35_12170	COG1266	CAAX protease self-immunity
CJO35_12175	COG0514	ATP-dependent DNA helicase (RecQ)
CJO35_12180	COG4955	Helix-turn-helix domain
CJO35_12185	COG1141	Ferredoxin
CJO35_12190	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CJO35_12195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJO35_12200	COG0739	heme binding
CJO35_12210	COG1595	DNA-templated transcription, initiation
CJO35_12230	COG5002	protein histidine kinase activity
CJO35_12235	COG0745	RESPONSE REGULATOR receiver
CJO35_12240	COG5002	protein histidine kinase activity
CJO35_12245	COG0745	RESPONSE REGULATOR receiver
CJO35_12250	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO35_12255	COG1333	cytochrome c biogenesis protein
CJO35_12260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_12265	COG1187	pseudouridine synthase activity
CJO35_12270	COG0700	Nucleoside recognition
CJO35_12275	COG2715	membrane protein required for spore maturation
CJO35_12280	COG1686	Belongs to the peptidase S11 family
CJO35_12290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CJO35_12295	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CJO35_12305	COG1547	Domain of unknown function (DUF309)
CJO35_12310	COG0456	acetyltransferase
CJO35_12315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJO35_12320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO35_12320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO35_12325	COG0307	riboflavin synthase, alpha
CJO35_12330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO35_12330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO35_12355	COG0457	Tetratricopeptide repeat
CJO35_12360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJO35_12365	COG4086	secreted protein
CJO35_12370	COG4195	phage-related replication protein
CJO35_12375	COG0019	diaminopimelate decarboxylase activity
CJO35_12385	COG0697	spore germination
CJO35_12400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO35_12435	COG1686	Belongs to the peptidase S11 family
CJO35_12440	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CJO35_12445	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CJO35_12450	COG4974	Belongs to the 'phage' integrase family
CJO35_12460	COG0735	belongs to the Fur family
CJO35_12465	COG1300	Membrane
CJO35_12470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_12490	COG2153	protein acetylation
CJO35_12495	COG1379	DNA repair
CJO35_12500	COG0494	nUDIX hydrolase
CJO35_12510	COG1309	transcriptional regulator
CJO35_12520	COG0667	Aldo Keto reductase
CJO35_12530	COG1073	alpha beta
CJO35_12540	COG4918	Iron-sulphur cluster biosynthesis
CJO35_12555	COG2329	Antibiotic biosynthesis monooxygenase
CJO35_12565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CJO35_12575	COG0747	negative chemotaxis
CJO35_12580	COG0601	transmembrane transport
CJO35_12590	COG0444	Belongs to the ABC transporter superfamily
CJO35_12600	COG0534	Mate efflux family protein
CJO35_12615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJO35_12625	COG2211	Major facilitator Superfamily
CJO35_12630	COG0346	lactoylglutathione lyase activity
CJO35_12635	COG1072	(Pantothenic acid kinase))
CJO35_12670	COG4195	phage-related replication protein
CJO35_12680	COG0300	oxidoreductase activity
CJO35_12685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_12690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJO35_12695	COG4187	Peptidase family M20/M25/M40
CJO35_12700	COG1902	pentaerythritol trinitrate reductase activity
CJO35_12705	COG0596	Alpha beta hydrolase
CJO35_12710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO35_12715	COG1234	tRNA 3'-trailer cleavage
CJO35_12720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CJO35_12740	COG2188	Transcriptional regulator
CJO35_12745	COG2723	6-phospho-beta-galactosidase activity
CJO35_12750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_12755	COG1447	Phosphotransferase system cellobiose-specific component IIA
CJO35_12760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_12765	COG1785	Belongs to the alkaline phosphatase family
CJO35_12770	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_12775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CJO35_12780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJO35_12790	COG0706	membrane insertase activity
CJO35_12795	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJO35_12800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO35_12805	COG4129	membrane
CJO35_12810	COG1126	abc transporter atp-binding protein
CJO35_12815	COG0765	amino acid transport
CJO35_12820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJO35_12830	COG1597	lipid kinase activity
CJO35_12835	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO35_12840	COG0022	dehydrogenase e1 component
CJO35_12845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO35_12850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO35_12855	COG3426	butyrate kinase activity
CJO35_12865	COG0280	phosphate acetyltransferase
CJO35_12870	COG3290	protein histidine kinase activity
CJO35_12870	COG3829	transcription factor binding
CJO35_12880	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_12885	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_12900	COG1045	serine acetyltransferase
CJO35_12910	COG0745	RESPONSE REGULATOR receiver
CJO35_12915	COG0750	zinc metalloprotease
CJO35_12920	COG0497	DNA recombination
CJO35_12925	COG1438	arginine binding
CJO35_12930	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CJO35_12935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJO35_12940	COG0142	geranyltranstransferase activity
CJO35_12945	COG1722	exodeoxyribonuclease VII activity
CJO35_12950	COG1570	exodeoxyribonuclease VII activity
CJO35_12955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJO35_12960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO35_12965	COG1302	Protein conserved in bacteria
CJO35_12970	COG0439	Biotin carboxylase
CJO35_12975	COG0511	ligase activity, forming carbon-carbon bonds
CJO35_13015	COG3854	ATPases associated with a variety of cellular activities
CJO35_13025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJO35_13030	COG0006	proline dipeptidase activity
CJO35_13035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJO35_13045	COG3872	metal-dependent enzyme
CJO35_13055	COG1752	Esterase of the alpha-beta hydrolase superfamily
CJO35_13060	COG1321	iron dependent repressor
CJO35_13065	COG0095	Lipoate-protein ligase
CJO35_13070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_13075	COG2113	Glycine betaine
CJO35_13080	COG4176	ABC-type proline glycine betaine transport system permease component
CJO35_13085	COG4175	Glycine betaine
CJO35_13085	COG0517	IMP dehydrogenase activity
CJO35_13090	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO35_13095	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO35_13100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJO35_13105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJO35_13130	COG0681	Belongs to the peptidase S26 family
CJO35_13155	COG4940	Competence protein ComGF
CJO35_13165	COG4970	Tfp pilus assembly protein FimT
CJO35_13170	COG4537	Required for transformation and DNA binding
CJO35_13175	COG1459	type II secretion system
CJO35_13180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CJO35_13185	COG1366	Belongs to the anti-sigma-factor antagonist family
CJO35_13195	COG1393	Belongs to the ArsC family
CJO35_13205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_13215	COG0011	TIGRFAM Protein of
CJO35_13225	COG2866	Carboxypeptidase
CJO35_13230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_13235	COG1368	sulfuric ester hydrolase activity
CJO35_13240	COG1940	carbohydrate kinase activity
CJO35_13245	COG4483	Protein conserved in bacteria
CJO35_13250	COG0697	spore germination
CJO35_13255	COG0457	Tetratricopeptide repeat
CJO35_13255	COG0705	Rhomboid family
CJO35_13265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CJO35_13270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO35_13275	COG0438	transferase activity, transferring glycosyl groups
CJO35_13290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJO35_13295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJO35_13300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJO35_13305	COG0581	inorganic phosphate transmembrane transporter activity
CJO35_13310	COG0573	inorganic phosphate transmembrane transporter activity
CJO35_13315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJO35_13325	COG0477	Major facilitator Superfamily
CJO35_13330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CJO35_13335	COG2839	Protein conserved in bacteria
CJO35_13340	COG5521	maltodextrose utilization protein MalA
CJO35_13345	COG1388	LysM domain
CJO35_13350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CJO35_13355	COG4709	membrane
CJO35_13360	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CJO35_13365	COG0735	belongs to the Fur family
CJO35_13370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CJO35_13375	COG1121	(ABC) transporter
CJO35_13380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_13390	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CJO35_13395	COG0513	Belongs to the DEAD box helicase family
CJO35_13405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CJO35_13410	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJO35_13415	COG2384	SAM-dependent methyltransferase
CJO35_13470	COG5444	nuclease activity
CJO35_13485	COG2010	Cytochrome c
CJO35_13490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJO35_13495	COG0358	DNA primase activity
CJO35_13500	COG1671	Belongs to the UPF0178 family
CJO35_13505	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CJO35_13510	COG0517	IMP dehydrogenase activity
CJO35_13515	COG0751	glycine-tRNA ligase activity
CJO35_13520	COG0752	glycyl-tRNA synthetase alpha subunit
CJO35_13525	COG1381	Involved in DNA repair and RecF pathway recombination
CJO35_13535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJO35_13540	COG0295	cytidine deaminase activity
CJO35_13545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CJO35_13550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJO35_13555	COG1480	7TM receptor with intracellular HD hydrolase
CJO35_13560	COG1702	phosphate starvation-inducible protein PhoH
CJO35_13565	COG0561	phosphatase activity
CJO35_13580	COG4864	UPF0365 protein
CJO35_13585	COG1030	water channel activity
CJO35_13590	COG1610	YqeY-like protein
CJO35_13595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJO35_13600	COG1283	sodium-dependent phosphate transmembrane transporter activity
CJO35_13605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CJO35_13610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO35_13615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJO35_13620	COG2264	protein methyltransferase activity
CJO35_13625	COG0484	heat shock protein binding
CJO35_13630	COG0443	Heat shock 70 kDa protein
CJO35_13635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJO35_13640	COG1420	regulation of RNA biosynthetic process
CJO35_13645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO35_13650	COG0481	GTPase activity
CJO35_13660	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_13665	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CJO35_13670	COG0268	Binds directly to 16S ribosomal RNA
CJO35_13675	COG1466	dna polymerase III delta subunit
CJO35_13685	COG2333	competence protein COMEC
CJO35_13685	COG0658	competence protein
CJO35_13690	COG2131	deaminase
CJO35_13695	COG1555	photosystem II stabilization
CJO35_13695	COG1596	polysaccharide export
CJO35_13700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJO35_13705	COG2226	methyltransferase
CJO35_13710	COG0799	negative regulation of ribosome biogenesis
CJO35_13715	COG1713	HD superfamily hydrolase involved in NAD metabolism
CJO35_13720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJO35_13725	COG1534	Rna-binding protein
CJO35_13730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJO35_13735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CJO35_13740	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CJO35_13750	COG2755	lipolytic protein G-D-S-L family
CJO35_13755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_13760	COG5609	conserved protein (DUF2294)
CJO35_13765	COG3383	formate dehydrogenase (NAD+) activity
CJO35_13770	COG2427	Protein of unknown function (DUF1641)
CJO35_13805	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_13870	COG2197	response regulator
CJO35_13875	COG4585	Histidine kinase
CJO35_13880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_13885	COG0730	response to heat
CJO35_13890	COG0425	Belongs to the sulfur carrier protein TusA family
CJO35_13895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_13895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_13900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_13900	COG0425	Belongs to the sulfur carrier protein TusA family
CJO35_13905	COG2210	Belongs to the sulfur carrier protein TusA family
CJO35_13910	COG1937	Protein conserved in bacteria
CJO35_13950	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJO35_13955	COG0113	porphobilinogen synthase activity
CJO35_13960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CJO35_13965	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CJO35_13970	COG1733	regulation of RNA biosynthetic process
CJO35_13975	COG3239	Fatty acid desaturase
CJO35_13980	COG4585	Histidine kinase
CJO35_13985	COG2197	response regulator
CJO35_13990	COG0492	ferredoxin-NADP+ reductase activity
CJO35_13995	COG0747	negative chemotaxis
CJO35_14000	COG0601	transmembrane transport
CJO35_14010	COG0444	Belongs to the ABC transporter superfamily
CJO35_14015	COG4608	Belongs to the ABC transporter superfamily
CJO35_14035	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_14050	COG2124	cytochrome p450
CJO35_14055	COG0730	response to heat
CJO35_14070	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_14075	COG1621	beta-fructofuranosidase activity
CJO35_14080	COG3716	PTS system mannose fructose sorbose family IID component
CJO35_14085	COG3715	PTS system
CJO35_14090	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_14095	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_14100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CJO35_14100	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CJO35_14125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO35_14130	COG0656	L-ascorbic acid biosynthetic process
CJO35_14135	COG2814	Major facilitator Superfamily
CJO35_14140	COG1733	regulation of RNA biosynthetic process
CJO35_14145	COG3340	Belongs to the peptidase S51 family
CJO35_14150	COG1587	Uroporphyrinogen-III synthase
CJO35_14160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_14165	COG0583	DNA-binding transcription factor activity
CJO35_14170	COG2814	Major facilitator Superfamily
CJO35_14180	COG2124	cytochrome p450
CJO35_14180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CJO35_14185	COG1309	transcriptional regulator
CJO35_14190	COG1404	Belongs to the peptidase S8 family
CJO35_14195	COG2226	methyltransferase
CJO35_14220	COG0626	cystathionine gamma-synthase activity
CJO35_14225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO35_14230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJO35_14235	COG2226	methyltransferase
CJO35_14250	COG0768	penicillin binding
CJO35_14255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJO35_14260	COG0572	uridine kinase
CJO35_14280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJO35_14285	COG3906	Belongs to the UPF0473 family
CJO35_14290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJO35_14295	COG4472	Bacterial protein of unknown function (DUF965)
CJO35_14300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJO35_14305	COG0628	permease
CJO35_14320	COG3881	PFAM PRC-barrel domain
CJO35_14325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJO35_14330	COG0457	Tetratricopeptide repeat
CJO35_14335	COG0482	sulfurtransferase activity
CJO35_14340	COG1104	cysteine desulfurase activity
CJO35_14345	COG1959	2 iron, 2 sulfur cluster binding
CJO35_14350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJO35_14355	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CJO35_14365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJO35_14370	COG0124	histidyl-tRNA synthetase
CJO35_14380	COG3103	Sh3 type 3 domain protein
CJO35_14380	COG4991	sh3 domain protein
CJO35_14380	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_14385	COG1490	D-aminoacyl-tRNA deacylase activity
CJO35_14390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJO35_14395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO35_14400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CJO35_14400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CJO35_14405	COG5416	Lipopolysaccharide assembly protein A domain
CJO35_14410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO35_14410	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO35_14420	COG2244	polysaccharide biosynthetic process
CJO35_14425	COG2323	membrane
CJO35_14435	COG1862	Preprotein translocase
CJO35_14440	COG0343	queuine tRNA-ribosyltransferase activity
CJO35_14445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJO35_14455	COG2255	four-way junction helicase activity
CJO35_14460	COG0632	four-way junction helicase activity
CJO35_14470	COG2112	serine threonine protein kinase
CJO35_14480	COG2318	DinB family
CJO35_14485	COG4195	phage-related replication protein
CJO35_14500	COG0217	transcriptional regulatory protein
CJO35_14510	COG1388	LysM domain
CJO35_14515	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJO35_14520	COG0157	Belongs to the NadC ModD family
CJO35_14525	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJO35_14530	COG1104	cysteine desulfurase activity
CJO35_14535	COG1827	regulation of RNA biosynthetic process
CJO35_14540	COG0077	Prephenate dehydratase
CJO35_14545	COG4492	Belongs to the UPF0735 family
CJO35_14550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJO35_14555	COG3290	protein histidine kinase activity
CJO35_14560	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJO35_14565	COG2868	ribosomal protein
CJO35_14570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJO35_14575	COG1994	Peptidase M50
CJO35_14580	COG0739	heme binding
CJO35_14585	COG3832	glyoxalase III activity
CJO35_14590	COG0640	Transcriptional regulator
CJO35_14595	COG2894	cell division
CJO35_14600	COG0850	regulation of cytokinetic process
CJO35_14605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CJO35_14610	COG1792	Involved in formation and maintenance of cell shape
CJO35_14615	COG1077	Cell shape determining protein MreB Mrl
CJO35_14625	COG0424	maF-like protein
CJO35_14635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CJO35_14640	COG0285	dihydrofolate synthase activity
CJO35_14645	COG0525	valine-tRNA ligase activity
CJO35_14655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJO35_14660	COG1388	LysM domain
CJO35_14665	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CJO35_14670	COG0113	porphobilinogen synthase activity
CJO35_14675	COG1587	Uroporphyrinogen-III synthase
CJO35_14680	COG0181	hydroxymethylbilane synthase activity
CJO35_14685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO35_14690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CJO35_14700	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJO35_14705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CJO35_14710	COG0470	DNA polymerase III
CJO35_14710	COG1067	ATP-dependent peptidase activity
CJO35_14715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJO35_14720	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJO35_14725	COG0457	Tetratricopeptide repeat
CJO35_14725	COG1477	protein flavinylation
CJO35_14730	COG0066	3-isopropylmalate dehydratase activity
CJO35_14735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJO35_14740	COG0473	3-isopropylmalate dehydrogenase activity
CJO35_14745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO35_14750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJO35_14755	COG0440	acetolactate synthase activity
CJO35_14760	COG0028	Belongs to the TPP enzyme family
CJO35_14765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJO35_14775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJO35_14795	COG5518	Phage portal protein
CJO35_14850	COG5444	nuclease activity
CJO35_14855	COG0457	Tetratricopeptide repeat
CJO35_14875	COG0622	Phosphoesterase
CJO35_14880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJO35_14885	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CJO35_14890	COG5401	PFAM Sporulation and spore germination
CJO35_14895	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJO35_14900	COG1846	Transcriptional regulator
CJO35_14905	COG2197	response regulator
CJO35_14910	COG4221	oxidoreductase activity
CJO35_14915	COG0824	Thioesterase
CJO35_14920	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJO35_14925	COG1053	succinate dehydrogenase
CJO35_14930	COG2009	succinate dehydrogenase
CJO35_14935	COG1719	4-vinyl reductase, 4VR
CJO35_14940	COG0527	aspartate kinase activity
CJO35_14945	COG0322	excinuclease ABC activity
CJO35_14950	COG3118	belongs to the thioredoxin family
CJO35_14955	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CJO35_14960	COG2086	electron transfer activity
CJO35_14965	COG1024	Enoyl-CoA hydratase
CJO35_14970	COG1309	transcriptional regulator
CJO35_14975	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_14980	COG3766	membrane
CJO35_14985	COG1193	negative regulation of DNA recombination
CJO35_14990	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CJO35_14990	COG1796	DNA polymerase
CJO35_14995	COG1286	toxin biosynthetic process
CJO35_15000	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CJO35_15005	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJO35_15030	COG1137	ATPase activity
CJO35_15045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_15045	COG0072	phenylalanine-tRNA ligase activity
CJO35_15050	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJO35_15055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO35_15065	COG1966	Carbon starvation protein
CJO35_15080	COG0395	ABC-type sugar transport system, permease component
CJO35_15085	COG1175	transmembrane transport
CJO35_15090	COG1653	transport
CJO35_15095	COG0371	Dehydrogenase
CJO35_15100	COG0235	Class ii aldolase
CJO35_15105	COG1069	ribulokinase activity
CJO35_15110	COG2160	L-arabinose isomerase activity
CJO35_15115	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_15120	COG1363	Peptidase, m42
CJO35_15130	COG3326	Membrane
CJO35_15135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJO35_15140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJO35_15145	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJO35_15150	COG1346	cytolysis
CJO35_15160	COG3540	Alkaline phosphatase
CJO35_15165	COG3279	Response regulator of the LytR AlgR family
CJO35_15170	COG3275	phosphorelay sensor kinase activity
CJO35_15185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJO35_15195	COG0398	Pfam SNARE associated Golgi protein
CJO35_15200	COG1484	DNA-dependent DNA replication
CJO35_15205	COG3611	Membrane attachment protein
CJO35_15210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJO35_15225	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CJO35_15230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJO35_15235	COG3866	Pectate lyase
CJO35_15240	COG0237	dephospho-CoA kinase activity
CJO35_15245	COG1971	Probably functions as a manganese efflux pump
CJO35_15250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CJO35_15255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO35_15255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO35_15260	COG5002	protein histidine kinase activity
CJO35_15265	COG0745	RESPONSE REGULATOR receiver
CJO35_15270	COG0039	L-malate dehydrogenase activity
CJO35_15275	COG0538	isocitrate dehydrogenase activity
CJO35_15280	COG0372	Belongs to the citrate synthase family
CJO35_15285	COG2707	UPF0756 membrane protein
CJO35_15290	COG0628	permease
CJO35_15295	COG3030	protein affecting phage T7 exclusion by the F plasmid
CJO35_15305	COG0205	6-phosphofructokinase activity
CJO35_15310	COG0825	malonyl-CoA metabolic process
CJO35_15315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJO35_15320	COG0281	malic enzyme
CJO35_15325	COG0587	DNA-directed DNA polymerase activity
CJO35_15345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CJO35_15355	COG4109	DRTGG domain
CJO35_15360	COG1695	Transcriptional regulator
CJO35_15365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CJO35_15370	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_15375	COG0165	Argininosuccinate lyase
CJO35_15380	COG0137	argininosuccinate synthase activity
CJO35_15385	COG0521	Mo-molybdopterin cofactor biosynthetic process
CJO35_15390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CJO35_15395	COG0827	DNA restriction-modification system
CJO35_15400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CJO35_15405	COG3874	Sporulation protein YtfJ
CJO35_15415	COG1714	RDD family
CJO35_15420	COG0616	signal peptide processing
CJO35_15425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJO35_15430	COG1566	PFAM secretion protein HlyD family protein
CJO35_15435	COG0477	Major facilitator Superfamily
CJO35_15445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO35_15455	COG0301	tRNA thio-modification
CJO35_15460	COG1104	cysteine desulfurase activity
CJO35_15465	COG1114	Component of the transport system for branched-chain amino acids
CJO35_15470	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CJO35_15475	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CJO35_15480	COG1309	transcriptional regulator
CJO35_15485	COG1956	GAF domain-containing protein
CJO35_15500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJO35_15515	COG3152	Membrane
CJO35_15520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CJO35_15525	COG1522	sequence-specific DNA binding
CJO35_15530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJO35_15535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO35_15540	COG0454	-acetyltransferase
CJO35_15545	COG0517	IMP dehydrogenase activity
CJO35_15550	COG0123	including yeast histone deacetylase and acetoin utilization protein
CJO35_15555	COG1360	Flagellar Motor Protein
CJO35_15560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CJO35_15565	COG1609	Transcriptional regulator
CJO35_15570	COG1605	Chorismate mutase
CJO35_15570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CJO35_15580	COG3118	belongs to the thioredoxin family
CJO35_15585	COG4980	gas vesicle protein
CJO35_15590	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CJO35_15595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO35_15600	COG1674	ftsk spoiiie
CJO35_15605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO35_15610	COG4848	Belongs to the UPF0354 family
CJO35_15615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_15625	COG1363	Peptidase, m42
CJO35_15630	COG5584	Small secreted protein
CJO35_15635	COG0281	malic enzyme
CJO35_15640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO35_15645	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJO35_15655	COG0510	thiamine kinase activity
CJO35_15660	COG1523	belongs to the glycosyl hydrolase 13 family
CJO35_15665	COG1597	lipid kinase activity
CJO35_15675	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CJO35_15680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO35_15695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO35_15700	COG2252	PERMEase
CJO35_15705	COG1349	DNA-binding transcription factor activity
CJO35_15710	COG1187	pseudouridine synthase activity
CJO35_15715	COG2244	polysaccharide biosynthetic process
CJO35_15720	COG2081	HI0933 family
CJO35_15725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CJO35_15735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO35_15750	COG5578	integral membrane protein
CJO35_15755	COG0673	inositol 2-dehydrogenase activity
CJO35_15760	COG1653	transport
CJO35_15765	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CJO35_15770	COG4209	transmembrane transport
CJO35_15775	COG2207	Transcriptional regulator
CJO35_15780	COG1653	transport
CJO35_15785	COG0395	ABC-type sugar transport system, permease component
CJO35_15790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO35_15795	COG1073	alpha beta
CJO35_15805	COG0583	DNA-binding transcription factor activity
CJO35_15810	COG0346	lactoylglutathione lyase activity
CJO35_15815	COG0495	leucyl-tRNA aminoacylation
CJO35_15825	COG2814	Major facilitator Superfamily
CJO35_15835	COG2433	Pfam Transposase IS66
CJO35_15840	COG0577	efflux transmembrane transporter activity
CJO35_15845	COG1136	(ABC) transporter
CJO35_15855	COG1131	(ABC) transporter
CJO35_15860	COG1725	Transcriptional regulator
CJO35_15870	COG1242	4 iron, 4 sulfur cluster binding
CJO35_15875	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CJO35_15880	COG1301	dicarboxylic acid transport
CJO35_15890	COG2267	carboxylic ester hydrolase activity
CJO35_15895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CJO35_15900	COG0671	phosphoesterase, PA-phosphatase related
CJO35_15905	COG0438	transferase activity, transferring glycosyl groups
CJO35_15905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_15910	COG0367	asparagine synthase
CJO35_15915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJO35_15920	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CJO35_15925	COG1301	dicarboxylic acid transport
CJO35_15935	COG1506	peptidase
CJO35_15940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CJO35_15945	COG1116	anion transmembrane transporter activity
CJO35_15950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJO35_15955	COG0494	nUDIX hydrolase
CJO35_15965	COG4824	toxin secretion phage lysis holin
CJO35_15970	COG0783	Belongs to the Dps family
CJO35_15985	COG1854	S-ribosylhomocysteine lyase activity
CJO35_15990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJO35_15995	COG0288	reversible hydration of carbon dioxide
CJO35_16000	COG0523	cobalamin synthesis protein
CJO35_16005	COG0803	Belongs to the bacterial solute-binding protein 9 family
CJO35_16010	COG0254	rRNA binding
CJO35_16015	COG1271	oxidase subunit
CJO35_16020	COG1294	oxidase, subunit
CJO35_16035	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_16040	COG0318	PFAM AMP-dependent synthetase and ligase
CJO35_16045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CJO35_16050	COG0596	Alpha beta hydrolase
CJO35_16055	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CJO35_16060	COG1169	isochorismate synthase
CJO35_16065	COG1575	Belongs to the MenA family. Type 1 subfamily
CJO35_16070	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CJO35_16075	COG0058	SHG alpha-glucan phosphorylase activity
CJO35_16080	COG0297	glycogen (starch) synthase activity
CJO35_16085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CJO35_16090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CJO35_16095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CJO35_16220	COG1609	Transcriptional regulator
CJO35_16225	COG3859	Proton-coupled thiamine transporter YuaJ
CJO35_16230	COG3764	Sortase (surface protein transpeptidase)
CJO35_16245	COG0457	Tetratricopeptide repeat
CJO35_16250	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJO35_16255	COG0569	domain protein
CJO35_16260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJO35_16270	COG2318	DinB family
CJO35_16280	COG1454	alcohol dehydrogenase
CJO35_16290	COG1510	regulation of RNA biosynthetic process
CJO35_16300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CJO35_16305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJO35_16310	COG2140	Oxalate decarboxylase
CJO35_16340	COG1397	ADP-ribosylglycohydrolase
CJO35_16375	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CJO35_16385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO35_16390	COG0726	polysaccharide deacetylase
CJO35_16395	COG1408	metallophosphoesterase
CJO35_16400	COG1968	undecaprenyl-diphosphatase activity
CJO35_16405	COG0628	permease
CJO35_16410	COG0673	inositol 2-dehydrogenase activity
CJO35_16415	COG0693	protein deglycase activity
CJO35_16420	COG0840	transmembrane signaling receptor activity
CJO35_16425	COG0840	transmembrane signaling receptor activity
CJO35_16430	COG0840	transmembrane signaling receptor activity
CJO35_16440	COG2070	2-Nitropropane dioxygenase
CJO35_16445	COG0432	Pfam Uncharacterised protein family UPF0047
CJO35_16450	COG0366	Alpha amylase catalytic
CJO35_16465	COG5297	Belongs to the glycosyl hydrolase family 6
CJO35_16470	COG1253	flavin adenine dinucleotide binding
CJO35_16475	COG2738	Putative neutral zinc metallopeptidase
CJO35_16485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJO35_16500	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CJO35_16510	COG0166	Belongs to the GPI family
CJO35_16515	COG1979	alcohol dehydrogenase
CJO35_16520	COG2155	Conserved Protein
CJO35_16525	COG1098	S1 RNA binding domain
CJO35_16530	COG0436	Aminotransferase
CJO35_16535	COG1522	sequence-specific DNA binding
CJO35_16540	COG2267	carboxylic ester hydrolase activity
CJO35_16555	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJO35_16570	COG5018	Exonuclease
CJO35_16575	COG2814	Major facilitator Superfamily
CJO35_16580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_16585	COG3011	Protein conserved in bacteria
CJO35_16595	COG3290	protein histidine kinase activity
CJO35_16600	COG4565	transcriptional regulatory protein
CJO35_16610	COG1183	phosphatidylcholine synthase activity
CJO35_16615	COG0586	Pfam SNARE associated Golgi protein
CJO35_16620	COG0688	phosphatidylethanolamine metabolic process
CJO35_16625	COG3493	citrate carrier protein
CJO35_16635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CJO35_16635	COG2111	Na H antiporter
CJO35_16640	COG2111	Na H antiporter
CJO35_16645	COG1006	Multisubunit Na H antiporter MnhC subunit
CJO35_16650	COG0651	ATP synthesis coupled electron transport
CJO35_16655	COG1863	multisubunit Na H antiporter MnhE subunit
CJO35_16660	COG2212	antiporter activity
CJO35_16665	COG1320	monovalent cation:proton antiporter activity
CJO35_16670	COG2050	protein possibly involved in aromatic compounds catabolism
CJO35_16675	COG2197	response regulator
CJO35_16680	COG4585	Histidine kinase
CJO35_16690	COG0142	geranyltranstransferase activity
CJO35_16710	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CJO35_16715	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CJO35_16720	COG1335	isochorismatase
CJO35_16725	COG5506	Protein of unknown function (DUF1694)
CJO35_16740	COG0628	permease
CJO35_16745	COG1959	2 iron, 2 sulfur cluster binding
CJO35_16760	COG1418	mRNA catabolic process
CJO35_16765	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_16775	COG1511	domain protein
CJO35_16780	COG0433	COG0433 Predicted ATPase
CJO35_16780	COG1674	ftsk spoiiie
CJO35_16785	COG4499	WXG100 protein secretion system (Wss), protein YukC
CJO35_16790	COG5417	Belongs to the EsaB family
CJO35_16795	COG4842	Belongs to the WXG100 family
CJO35_16800	COG1115	amino acid carrier protein
CJO35_16805	COG2508	Transcriptional regulator
CJO35_16805	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CJO35_16810	COG0686	Belongs to the AlaDH PNT family
CJO35_16820	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO35_16825	COG1268	BioY protein
CJO35_16830	COG2056	Na+-H+ antiporter family
CJO35_16835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJO35_16840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CJO35_16845	COG3584	3D domain protein
CJO35_16855	COG1252	NADH dehydrogenase
CJO35_16860	COG0492	ferredoxin-NADP+ reductase activity
CJO35_16875	COG0456	acetyltransferase
CJO35_16880	COG0316	Belongs to the HesB IscA family
CJO35_16885	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJO35_16890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CJO35_16895	COG4844	belongs to the
CJO35_16900	COG1252	NADH dehydrogenase
CJO35_16905	COG5646	InterPro IPR014922
CJO35_16915	COG0457	Tetratricopeptide repeat
CJO35_16930	COG4837	Protein of unknown function (DUF1462)
CJO35_16935	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CJO35_16940	COG0823	Involved in the tonB-independent uptake of proteins
CJO35_16940	COG4946	Tricorn protease homolog
CJO35_16940	COG1506	peptidase
CJO35_16945	COG0083	homoserine kinase activity
CJO35_16950	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CJO35_16955	COG0460	homoserine dehydrogenase
CJO35_16965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJO35_16970	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CJO35_16975	COG0647	UMP catabolic process
CJO35_16980	COG2445	Protein of unknown function DUF86
CJO35_16985	COG4470	Protein conserved in bacteria
CJO35_17000	COG0739	heme binding
CJO35_17010	COG0733	neurotransmitter:sodium symporter activity
CJO35_17020	COG3377	Domain of unknown function (DUF1805)
CJO35_17025	COG0737	Belongs to the 5'-nucleotidase family
CJO35_17030	COG0730	response to heat
CJO35_17035	COG1801	Protein of unknown function DUF72
CJO35_17045	COG3226	Transcriptional regulator
CJO35_17055	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CJO35_17060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO35_17065	COG2508	Transcriptional regulator
CJO35_17070	COG2814	Major facilitator Superfamily
CJO35_17075	COG1288	antiporter activity
CJO35_17080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO35_17090	COG2356	endonuclease I
CJO35_17100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO35_17115	COG0457	Tetratricopeptide repeat
CJO35_17120	COG0719	Fe-S assembly protein
CJO35_17125	COG0822	iron-sulfur transferase activity
CJO35_17130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJO35_17135	COG0719	Fe-S assembly protein
CJO35_17140	COG0396	ATPase activity
CJO35_17150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO35_17155	COG1464	Belongs to the NlpA lipoprotein family
CJO35_17160	COG2011	ABC-type metal ion transport system permease component
CJO35_17165	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJO35_17175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO35_17180	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CJO35_17190	COG0509	glycine decarboxylation via glycine cleavage system
CJO35_17195	COG1393	Belongs to the ArsC family
CJO35_17200	COG1960	acyl-CoA dehydrogenase activity
CJO35_17205	COG0183	Belongs to the thiolase family
CJO35_17210	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO35_17210	COG1024	Enoyl-CoA hydratase
CJO35_17225	COG5577	PFAM Coat F domain
CJO35_17240	COG1120	ATPase activity
CJO35_17245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_17250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_17255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_17270	COG1686	Belongs to the peptidase S11 family
CJO35_17275	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_17280	COG0783	Belongs to the Dps family
CJO35_17285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_17290	COG0745	RESPONSE REGULATOR receiver
CJO35_17295	COG2205	protein histidine kinase activity
CJO35_17295	COG2770	Histidine kinase
CJO35_17305	COG1309	transcriptional regulator
CJO35_17310	COG0114	fumarate hydratase activity
CJO35_17320	COG0697	spore germination
CJO35_17325	COG0814	amino acid
CJO35_17340	COG2197	response regulator
CJO35_17345	COG4585	Histidine kinase
CJO35_17350	COG4758	membrane
CJO35_17360	COG1842	Phage shock protein A
CJO35_17365	COG4758	membrane
CJO35_17370	COG4677	pectinesterase activity
CJO35_17375	COG2096	Adenosyltransferase
CJO35_17380	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_17395	COG1454	alcohol dehydrogenase
CJO35_17400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO35_17405	COG1120	ATPase activity
CJO35_17410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_17415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_17420	COG1802	Transcriptional regulator
CJO35_17425	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_17430	COG2258	MOSC domain
CJO35_17435	COG0583	DNA-binding transcription factor activity
CJO35_17445	COG2721	sulfolactate sulfo-lyase activity
CJO35_17450	COG0246	Mannitol dehydrogenase
CJO35_17455	COG1609	Transcriptional regulator
CJO35_17460	COG2211	Major facilitator Superfamily
CJO35_17465	COG1904	glucuronate isomerase
CJO35_17470	COG2205	protein histidine kinase activity
CJO35_17475	COG0745	RESPONSE REGULATOR receiver
CJO35_17480	COG1120	ATPase activity
CJO35_17485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_17490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_17495	COG0531	amino acid
CJO35_17505	COG1988	membrane-bound metal-dependent
CJO35_17510	COG1368	sulfuric ester hydrolase activity
CJO35_17515	COG2814	Major facilitator Superfamily
CJO35_17520	COG0656	L-ascorbic acid biosynthetic process
CJO35_17525	COG1940	carbohydrate kinase activity
CJO35_17530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJO35_17540	COG3973	AAA domain
CJO35_17545	COG2860	membrane
CJO35_17550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CJO35_17550	COG0456	acetyltransferase
CJO35_17555	COG0456	acetyltransferase
CJO35_17560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CJO35_17565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CJO35_17570	COG2217	Heavy metal translocating P-type atpase
CJO35_17580	COG1175	transmembrane transport
CJO35_17585	COG0395	ABC-type sugar transport system, permease component
CJO35_17590	COG1501	Belongs to the glycosyl hydrolase 31 family
CJO35_17595	COG1472	Belongs to the glycosyl hydrolase 3 family
CJO35_17600	COG1121	(ABC) transporter
CJO35_17605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CJO35_17610	COG0803	Belongs to the bacterial solute-binding protein 9 family
CJO35_17630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_17630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_17630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CJO35_17645	COG2217	Heavy metal translocating P-type atpase
CJO35_17650	COG2608	mercury ion transmembrane transporter activity
CJO35_17655	COG1937	Protein conserved in bacteria
CJO35_17660	COG0693	protein deglycase activity
CJO35_17665	COG1349	DNA-binding transcription factor activity
CJO35_17670	COG1070	Carbohydrate kinase
CJO35_17675	COG4952	isomerase
CJO35_17685	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_17685	COG3347	Dehydrogenase
CJO35_17695	COG2814	Major facilitator Superfamily
CJO35_17705	COG2124	cytochrome p450
CJO35_17715	COG1846	Transcriptional regulator
CJO35_17725	COG0673	inositol 2-dehydrogenase activity
CJO35_17730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJO35_17745	COG1191	sigma factor activity
CJO35_17755	COG2140	Oxalate decarboxylase
CJO35_17790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJO35_17880	COG1705	Flagellar rod assembly protein muramidase FlgJ
CJO35_17890	COG5280	Phage tail tape measure protein TP901
CJO35_17890	COG3953	SLT domain
CJO35_17950	COG4626	Terminase
CJO35_17950	COG1802	Transcriptional regulator
CJO35_18105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJO35_18110	COG0557	exoribonuclease II activity
CJO35_18115	COG1647	Serine aminopeptidase, S33
CJO35_18120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJO35_18125	COG2002	toxin-antitoxin pair type II binding
CJO35_18130	COG1476	TRANSCRIPTIONal
CJO35_18135	COG1396	sequence-specific DNA binding
CJO35_18140	COG1396	sequence-specific DNA binding
CJO35_18145	COG1174	glycine betaine transport
CJO35_18150	COG1732	Glycine betaine
CJO35_18155	COG1174	glycine betaine transport
CJO35_18160	COG1125	glycine betaine transport
CJO35_18160	COG0517	IMP dehydrogenase activity
CJO35_18165	COG1510	regulation of RNA biosynthetic process
CJO35_18170	COG2095	MarC family integral membrane protein
CJO35_18185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_18195	COG0693	protein deglycase activity
CJO35_18200	COG0148	phosphopyruvate hydratase activity
CJO35_18205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CJO35_18210	COG0149	triose-phosphate isomerase activity
CJO35_18215	COG0126	phosphoglycerate kinase activity
CJO35_18220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJO35_18225	COG2390	Transcriptional regulator
CJO35_18230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_18235	COG1113	amino acid transport
CJO35_18255	COG1556	Lactate utilization protein
CJO35_18260	COG1139	Iron-sulfur cluster binding protein
CJO35_18265	COG0247	lactate metabolic process
CJO35_18270	COG2186	Transcriptional regulator
CJO35_18275	COG1620	l-lactate permease
CJO35_18280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJO35_18290	COG5039	Polysaccharide pyruvyl transferase
CJO35_18295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO35_18300	COG0110	maltose O-acetyltransferase activity
CJO35_18305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJO35_18310	COG2244	polysaccharide biosynthetic process
CJO35_18315	COG1216	Glycosyl transferase, family 2
CJO35_18320	COG5039	Polysaccharide pyruvyl transferase
CJO35_18325	COG1216	Glycosyl transferase, family 2
CJO35_18335	COG0438	transferase activity, transferring glycosyl groups
CJO35_18340	COG1215	transferase activity, transferring glycosyl groups
CJO35_18345	COG0438	transferase activity, transferring glycosyl groups
CJO35_18350	COG1086	Polysaccharide biosynthesis protein
CJO35_18355	COG0489	protein tyrosine kinase activity
CJO35_18360	COG3944	biosynthesis protein
CJO35_18365	COG1396	sequence-specific DNA binding
CJO35_18370	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJO35_18375	COG2271	Major facilitator Superfamily
CJO35_18385	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJO35_18400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO35_18415	COG1902	pentaerythritol trinitrate reductase activity
CJO35_18420	COG1621	beta-fructofuranosidase activity
CJO35_18425	COG1621	beta-fructofuranosidase activity
CJO35_18440	COG0740	serine-type endopeptidase activity
CJO35_18445	COG1611	Belongs to the LOG family
CJO35_18450	COG1694	Mazg nucleotide pyrophosphohydrolase
CJO35_18455	COG1078	dGTPase activity
CJO35_18460	COG0659	secondary active sulfate transmembrane transporter activity
CJO35_18465	COG0288	reversible hydration of carbon dioxide
CJO35_18470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO35_18475	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CJO35_18480	COG0640	Transcriptional regulator
CJO35_18490	COG2732	(Barnase) inhibitor
CJO35_18495	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CJO35_18500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_18505	COG1481	regulation of sporulation
CJO35_18510	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CJO35_18515	COG1660	Displays ATPase and GTPase activities
CJO35_18520	COG1051	belongs to the nudix hydrolase family
CJO35_18530	COG0492	ferredoxin-NADP+ reductase activity
CJO35_18535	COG0457	Tetratricopeptide repeat
CJO35_18540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO35_18545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJO35_18545	COG0140	phosphoribosyl-ATP diphosphatase activity
CJO35_18550	COG0107	imidazoleglycerol-phosphate synthase activity
CJO35_18555	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJO35_18560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CJO35_18565	COG0131	Imidazoleglycerol-phosphate dehydratase
CJO35_18570	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJO35_18575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJO35_18580	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CJO35_18585	COG4990	cell redox homeostasis
CJO35_18590	COG5297	Belongs to the glycosyl hydrolase family 6
CJO35_18595	COG0110	maltose O-acetyltransferase activity
CJO35_18600	COG0546	phosphoglycolate phosphatase activity
CJO35_18605	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CJO35_18610	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJO35_18615	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CJO35_18620	COG1846	Transcriptional regulator
CJO35_18625	COG2814	Major facilitator Superfamily
CJO35_18630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CJO35_18635	COG1950	PFAM Membrane protein of
CJO35_18640	COG1983	PspC domain protein
CJO35_18645	COG3595	metallopeptidase activity
CJO35_18670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJO35_18675	COG0556	nucleotide-excision repair
CJO35_18680	COG4897	Protein conserved in bacteria
CJO35_18690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_18700	COG0793	Belongs to the peptidase S41A family
CJO35_18700	COG3409	Peptidoglycan-binding domain 1 protein
CJO35_18705	COG0473	3-isopropylmalate dehydrogenase activity
CJO35_18710	COG3883	PFAM NLP P60 protein
CJO35_18710	COG0791	NLP P60 protein
CJO35_18715	COG2177	Part of the ABC transporter FtsEX involved in
CJO35_18720	COG2884	Cell division ATP-binding protein ftsE
CJO35_18730	COG2010	Cytochrome c
CJO35_18735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_18745	COG0653	protein targeting
CJO35_18750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJO35_18765	COG1516	flagellar protein fliS
CJO35_18770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CJO35_18775	COG1334	flagellar protein FlaG
CJO35_18785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CJO35_18790	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CJO35_18795	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CJO35_18805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CJO35_18810	COG1256	bacterial-type flagellum assembly
CJO35_18810	COG4786	Flagellar basal body rod
CJO35_18815	COG3418	PFAM FlgN family protein
CJO35_18820	COG2747	anti-sigma28 factor FlgM
CJO35_18830	COG1040	competence protein
CJO35_18840	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CJO35_18845	COG1307	EDD domain protein, DegV family
CJO35_18850	COG2197	response regulator
CJO35_18855	COG4585	Histidine kinase
CJO35_18860	COG1739	Uncharacterized protein family UPF0029
CJO35_18865	COG1316	TRANSCRIPTIONal
CJO35_18875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO35_18880	COG0438	transferase activity, transferring glycosyl groups
CJO35_18885	COG1215	transferase activity, transferring glycosyl groups
CJO35_18890	COG3206	protein involved in exopolysaccharide biosynthesis
CJO35_18895	COG3307	-O-antigen
CJO35_18900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO35_18905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CJO35_18910	COG0438	transferase activity, transferring glycosyl groups
CJO35_18910	COG0297	glycogen (starch) synthase activity
CJO35_18915	COG2244	polysaccharide biosynthetic process
CJO35_18925	COG2247	cell wall binding repeat
CJO35_18925	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO35_18930	COG2385	sporulation resulting in formation of a cellular spore
CJO35_18930	COG2247	cell wall binding repeat
CJO35_18940	COG1316	TRANSCRIPTIONal
CJO35_18945	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJO35_18950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CJO35_18955	COG1134	teichoic acid transport
CJO35_18960	COG1682	transport, permease protein
CJO35_18965	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CJO35_18965	COG0463	Glycosyl transferase, family 2
CJO35_18970	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CJO35_18975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CJO35_18980	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CJO35_18985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CJO35_18995	COG1482	cell wall glycoprotein biosynthetic process
CJO35_19015	COG0800	Aldolase
CJO35_19020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_19025	COG1609	Transcriptional regulator
CJO35_19030	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CJO35_19035	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_19040	COG1063	alcohol dehydrogenase
CJO35_19045	COG2814	Major facilitator Superfamily
CJO35_19050	COG1316	TRANSCRIPTIONal
CJO35_19055	COG0561	phosphatase activity
CJO35_19060	COG0791	NLP P60 protein
CJO35_19070	COG2843	Capsule synthesis protein
CJO35_19080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJO35_19085	COG1609	Transcriptional regulator
CJO35_19090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_19095	COG1869	D-ribose catabolic process
CJO35_19100	COG1129	ABC transporter
CJO35_19105	COG1172	Belongs to the binding-protein-dependent transport system permease family
CJO35_19110	COG1879	ABC-type sugar transport system periplasmic component
CJO35_19120	COG3527	Alpha-acetolactate decarboxylase
CJO35_19125	COG0028	Belongs to the TPP enzyme family
CJO35_19130	COG0583	DNA-binding transcription factor activity
CJO35_19135	COG0405	Gamma-glutamyltransferase
CJO35_19140	COG1522	sequence-specific DNA binding
CJO35_19145	COG2059	Chromate
CJO35_19150	COG2059	Chromate
CJO35_19155	COG4464	protein tyrosine phosphatase activity
CJO35_19160	COG3944	biosynthesis protein
CJO35_19170	COG4715	Zinc finger, swim domain protein
CJO35_19175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJO35_19180	COG0561	phosphatase activity
CJO35_19185	COG1349	DNA-binding transcription factor activity
CJO35_19195	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_19205	COG3732	PTS system glucitol sorbitol-specific
CJO35_19225	COG0629	single-stranded DNA binding
CJO35_19240	COG1970	mechanosensitive ion channel activity
CJO35_19245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO35_19250	COG4786	Flagellar basal body rod
CJO35_19255	COG4786	Flagellar basal body rod
CJO35_19260	COG1077	Cell shape determining protein MreB Mrl
CJO35_19265	COG1609	Transcriptional regulator
CJO35_19275	COG1846	Transcriptional regulator
CJO35_19280	COG2814	Major facilitator Superfamily
CJO35_19285	COG0671	phosphoesterase, PA-phosphatase related
CJO35_19290	COG1227	inorganic diphosphatase activity
CJO35_19295	COG3546	catalase activity
CJO35_19300	COG3361	conserved protein (COG2071)
CJO35_19305	COG0517	IMP dehydrogenase activity
CJO35_19310	COG0598	Magnesium transport protein CorA
CJO35_19315	COG1253	flavin adenine dinucleotide binding
CJO35_19320	COG0004	ammonium transporteR
CJO35_19325	COG0347	Belongs to the P(II) protein family
CJO35_19330	COG0740	serine-type endopeptidase activity
CJO35_19340	COG0739	heme binding
CJO35_19345	COG1247	-acetyltransferase
CJO35_19355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO35_19365	COG0477	Major facilitator Superfamily
CJO35_19375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_19380	COG3433	isochorismatase activity
CJO35_19380	COG1535	isochorismatase
CJO35_19385	COG1021	2,3-dihydroxybenzoate-AMP ligase
CJO35_19390	COG1169	isochorismate synthase
CJO35_19395	COG1028	Short-chain dehydrogenase reductase Sdr
CJO35_19400	COG2819	hydrolase of the alpha beta superfamily
CJO35_19405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_19410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CJO35_19415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_19420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_19420	COG2207	Transcriptional regulator
CJO35_19430	COG2910	NAD(P)H-binding
CJO35_19435	COG1959	2 iron, 2 sulfur cluster binding
CJO35_19440	COG1994	Peptidase M50
CJO35_19445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJO35_19450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CJO35_19460	COG0243	molybdopterin cofactor binding
CJO35_19465	COG2304	oxidoreductase activity
CJO35_19470	COG2304	oxidoreductase activity
CJO35_19475	COG2385	sporulation resulting in formation of a cellular spore
CJO35_19480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJO35_19490	COG4836	Membrane
CJO35_19495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJO35_19500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJO35_19505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJO35_19510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJO35_19515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO35_19520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJO35_19525	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO35_19545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CJO35_19550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJO35_19555	COG4475	Protein of unknown function (DUF436)
CJO35_19560	COG0698	ribose 5-phosphate isomerase
CJO35_19565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO35_19570	COG1971	Probably functions as a manganese efflux pump
CJO35_19575	COG0009	L-threonylcarbamoyladenylate synthase
CJO35_19580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CJO35_19590	COG0738	Major facilitator superfamily
CJO35_19595	COG0673	inositol 2-dehydrogenase activity
CJO35_19600	COG0561	phosphatase activity
CJO35_19605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO35_19610	COG1609	Transcriptional regulator
CJO35_19615	COG2890	protein-(glutamine-N5) methyltransferase activity
CJO35_19620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJO35_19625	COG0346	lactoylglutathione lyase activity
CJO35_19630	COG0789	Transcriptional regulator
CJO35_19635	COG0679	Auxin Efflux Carrier
CJO35_19640	COG0281	malic enzyme
CJO35_19645	COG1435	thymidine kinase activity
CJO35_19650	COG0254	rRNA binding
CJO35_19655	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CJO35_19660	COG1494	fructose-1,6-bisphosphatase
CJO35_19665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJO35_19670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJO35_19675	COG0191	fructose-bisphosphate aldolase activity
CJO35_19680	COG2204	response regulator
CJO35_19685	COG4821	SIS domain
CJO35_19690	COG0504	CTP synthase activity
CJO35_19695	COG3343	RNA polymerase activity
CJO35_19700	COG1960	acyl-CoA dehydrogenase activity
CJO35_19705	COG1960	acyl-CoA dehydrogenase activity
CJO35_19710	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO35_19715	COG0183	Belongs to the thiolase family
CJO35_19720	COG0247	lactate metabolic process
CJO35_19720	COG2181	nitrate reductase activity
CJO35_19725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CJO35_19735	COG0018	arginyl-trna synthetase
CJO35_19740	COG4506	Protein conserved in bacteria
CJO35_19745	COG0010	Belongs to the arginase family
CJO35_19750	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CJO35_19765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJO35_19775	COG1994	Peptidase M50
CJO35_19780	COG1942	4-Oxalocrotonate Tautomerase
CJO35_19790	COG3465	dGTPase activity
CJO35_19795	COG1078	dGTPase activity
CJO35_19800	COG4844	belongs to the
CJO35_19825	COG2814	Major facilitator Superfamily
CJO35_19850	COG1414	Transcriptional regulator
CJO35_19860	COG0280	phosphate acetyltransferase
CJO35_19880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJO35_19900	COG1131	(ABC) transporter
CJO35_19915	COG2363	Small membrane protein
CJO35_19920	COG2233	PERMEase
CJO35_19930	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_19935	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CJO35_19940	COG1216	Glycosyl transferase, family 2
CJO35_19945	COG0351	phosphomethylpyrimidine kinase
CJO35_19955	COG1621	beta-fructofuranosidase activity
CJO35_19960	COG1263	PTS System
CJO35_19960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_19965	COG3711	transcriptional antiterminator
CJO35_19975	COG1404	Belongs to the peptidase S8 family
CJO35_19985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO35_19990	COG0778	Nitroreductase
CJO35_19995	COG1473	amidohydrolase
CJO35_20000	COG0772	Belongs to the SEDS family
CJO35_20005	COG0772	Belongs to the SEDS family
CJO35_20030	COG0456	acetyltransferase
CJO35_20065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CJO35_20075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO35_20080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO35_20085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_20105	COG3162	membrane
CJO35_20110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_20115	COG1070	Carbohydrate kinase
CJO35_20120	COG2115	Belongs to the xylose isomerase family
CJO35_20130	COG0352	thiamine-phosphate diphosphorylase activity
CJO35_20135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CJO35_20140	COG0583	DNA-binding transcription factor activity
CJO35_20155	COG1380	Effector of murein hydrolase LrgA
CJO35_20160	COG1346	cytolysis
CJO35_20170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO35_20175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CJO35_20180	COG0346	lactoylglutathione lyase activity
CJO35_20185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO35_20190	COG1442	glycosyl transferase family 8
CJO35_20205	COG4585	Histidine kinase
CJO35_20210	COG2197	response regulator
CJO35_20215	COG2409	Drug exporters of the RND superfamily
CJO35_20220	COG5522	Integral membrane protein (intg_mem_TP0381)
CJO35_20225	COG2271	Major facilitator Superfamily
CJO35_20230	COG4948	Mandelate Racemase Muconate Lactonizing
CJO35_20235	COG0800	Aldolase
CJO35_20240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_20250	COG2234	aminopeptidase activity
CJO35_20255	COG0477	Major facilitator Superfamily
CJO35_20265	COG2357	RelA SpoT domain protein
CJO35_20280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO35_20285	COG1696	Membrane protein involved in D-alanine export
CJO35_20290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO35_20295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CJO35_20300	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJO35_20305	COG2814	Major facilitator Superfamily
CJO35_20310	COG1486	melibiose metabolic process
CJO35_20315	COG1447	Phosphotransferase system cellobiose-specific component IIA
CJO35_20320	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_20325	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_20330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO35_20330	COG3711	transcriptional antiterminator
CJO35_20335	COG2094	Belongs to the DNA glycosylase MPG family
CJO35_20345	COG0372	Belongs to the citrate synthase family
CJO35_20350	COG2079	MmgE PrpD family protein
CJO35_20355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CJO35_20370	COG1132	(ABC) transporter
CJO35_20375	COG2755	lipolytic protein G-D-S-L family
CJO35_20390	COG2814	Major facilitator Superfamily
CJO35_20395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_20400	COG1131	(ABC) transporter
CJO35_20420	COG1595	DNA-templated transcription, initiation
CJO35_20425	COG2814	Major facilitator Superfamily
CJO35_20430	COG0753	catalase activity
CJO35_20435	COG0753	catalase activity
CJO35_20440	COG0735	belongs to the Fur family
CJO35_20450	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CJO35_20455	COG1131	(ABC) transporter
CJO35_20470	COG1131	(ABC) transporter
CJO35_20520	COG3866	Pectate lyase
CJO35_20525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJO35_20530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CJO35_20535	COG4988	ABC transporter
CJO35_20540	COG1294	oxidase, subunit
CJO35_20545	COG1271	oxidase subunit
CJO35_20555	COG2116	formate transmembrane transporter activity
CJO35_20565	COG0281	malic enzyme
CJO35_20570	COG1757	Na H antiporter
CJO35_20575	COG1027	Aspartate ammonia-lyase
CJO35_20580	COG0252	asparaginase activity
CJO35_20585	COG1396	sequence-specific DNA binding
CJO35_20590	COG2706	6-phosphogluconolactonase activity
CJO35_20595	COG0745	RESPONSE REGULATOR receiver
CJO35_20600	COG2205	protein histidine kinase activity
CJO35_20610	COG1136	(ABC) transporter
CJO35_20615	COG0577	efflux transmembrane transporter activity
CJO35_20620	COG5294	Protein conserved in bacteria
CJO35_20630	COG0726	polysaccharide deacetylase
CJO35_20635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJO35_20640	COG1215	transferase activity, transferring glycosyl groups
CJO35_20645	COG3493	citrate carrier protein
CJO35_20650	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_20665	COG1368	sulfuric ester hydrolase activity
CJO35_20675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CJO35_20690	COG2235	arginine
CJO35_20695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJO35_20705	COG0549	Belongs to the carbamate kinase family
CJO35_20720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJO35_20730	COG1595	DNA-templated transcription, initiation
CJO35_20740	COG2195	Cleaves the N-terminal amino acid of tripeptides
CJO35_20750	COG1621	beta-fructofuranosidase activity
CJO35_20755	COG2223	nitrite transmembrane transporter activity
CJO35_20765	COG1609	Transcriptional regulator
CJO35_20780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CJO35_20785	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CJO35_20790	COG0463	Glycosyl transferase, family 2
CJO35_20795	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_20820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CJO35_20825	COG0753	catalase activity
CJO35_20825	COG0693	protein deglycase activity
CJO35_20835	COG2723	6-phospho-beta-galactosidase activity
CJO35_20840	COG2190	(PTS) system
CJO35_20840	COG1263	PTS System
CJO35_20840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_20850	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CJO35_20855	COG1122	ATPase activity
CJO35_20860	COG4721	ABC-type cobalt transport system, permease component
CJO35_20865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJO35_20870	COG2224	Isocitrate lyase
CJO35_20875	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CJO35_20885	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CJO35_20890	COG0577	efflux transmembrane transporter activity
CJO35_20895	COG1136	(ABC) transporter
CJO35_20900	COG2205	protein histidine kinase activity
CJO35_20905	COG0745	RESPONSE REGULATOR receiver
CJO35_20910	COG2723	6-phospho-beta-galactosidase activity
CJO35_20915	COG1263	PTS System
CJO35_20915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_20915	COG2190	(PTS) system
CJO35_20925	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CJO35_20940	COG3507	Belongs to the glycosyl hydrolase 43 family
CJO35_20945	COG0513	Belongs to the DEAD box helicase family
CJO35_20975	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CJO35_20980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CJO35_20985	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CJO35_20990	COG2390	Transcriptional regulator
CJO35_21000	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CJO35_21005	COG3706	GGDEF domain
CJO35_21010	COG5298	Protein conserved in bacteria
CJO35_21015	COG1215	transferase activity, transferring glycosyl groups
CJO35_21025	COG3977	Valine--pyruvate aminotransferase
CJO35_21040	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJO35_21050	COG0191	fructose-bisphosphate aldolase activity
CJO35_21055	COG1082	Xylose isomerase domain protein TIM barrel
CJO35_21060	COG1082	Xylose isomerase domain protein TIM barrel
CJO35_21065	COG0673	inositol 2-dehydrogenase activity
CJO35_21070	COG2814	Major facilitator Superfamily
CJO35_21075	COG1082	Xylose isomerase domain protein TIM barrel
CJO35_21080	COG3962	Belongs to the TPP enzyme family
CJO35_21085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO35_21090	COG3718	enzyme involved in inositol metabolism
CJO35_21095	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_21100	COG1349	DNA-binding transcription factor activity
CJO35_21105	COG0667	Aldo Keto reductase
CJO35_21110	COG0584	glycerophosphoryl diester phosphodiesterase
CJO35_21115	COG2271	Major facilitator Superfamily
CJO35_21120	COG0326	Molecular chaperone. Has ATPase activity
CJO35_21125	COG0488	(ABC) transporter
CJO35_21130	COG0561	phosphatase activity
CJO35_21150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CJO35_21180	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CJO35_21185	COG0577	efflux transmembrane transporter activity
CJO35_21190	COG1136	(ABC) transporter
CJO35_21195	COG2205	protein histidine kinase activity
CJO35_21200	COG0745	RESPONSE REGULATOR receiver
CJO35_21210	COG5278	phosphoserine phosphatase activity
CJO35_21210	COG0840	transmembrane signaling receptor activity
CJO35_21215	COG1115	amino acid carrier protein
CJO35_21220	COG0686	Belongs to the AlaDH PNT family
CJO35_21225	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CJO35_21230	COG1874	Beta-galactosidase
CJO35_21235	COG3833	ABC-type maltose transport systems, permease component
CJO35_21240	COG1175	transmembrane transport
CJO35_21245	COG2182	Extracellular solute-binding protein
CJO35_21250	COG1609	Transcriptional regulator
CJO35_21260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJO35_21265	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CJO35_21270	COG1940	carbohydrate kinase activity
CJO35_21295	COG1012	belongs to the aldehyde dehydrogenase family
CJO35_21295	COG1454	alcohol dehydrogenase
CJO35_21300	COG0450	alkyl hydroperoxide reductase
CJO35_21305	COG3634	alkyl hydroperoxide reductase activity
CJO35_21330	COG1131	(ABC) transporter
CJO35_21335	COG0842	Transport permease protein
CJO35_21340	COG4585	Histidine kinase
CJO35_21345	COG2197	response regulator
CJO35_21370	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJO35_21385	COG0456	acetyltransferase
CJO35_21400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJO35_21405	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CJO35_21410	COG4853	Protein conserved in bacteria
CJO35_21415	COG4863	YycH protein
CJO35_21420	COG5002	protein histidine kinase activity
CJO35_21425	COG0745	RESPONSE REGULATOR receiver
CJO35_21450	COG1051	belongs to the nudix hydrolase family
CJO35_21455	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJO35_21465	COG0305	Participates in initiation and elongation during chromosome replication
CJO35_21480	COG3093	addiction module antidote protein HigA
CJO35_21485	COG2807	transmembrane transport
CJO35_21490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CJO35_21495	COG0363	glucosamine-6-phosphate deaminase activity
CJO35_21505	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CJO35_21510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO35_21510	COG1263	PTS System
CJO35_21515	COG0359	binds to the 23S rRNA
CJO35_21520	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CJO35_21525	COG4241	membrane
CJO35_21535	COG5577	PFAM Coat F domain
CJO35_21540	COG0589	response to stress
CJO35_21545	COG0659	secondary active sulfate transmembrane transporter activity
CJO35_21550	COG2271	Major facilitator Superfamily
CJO35_21555	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJO35_21560	COG0629	single-stranded DNA binding
CJO35_21565	COG0360	Binds together with S18 to 16S ribosomal RNA
CJO35_21570	COG0012	GTP binding
CJO35_21580	COG4481	Protein conserved in bacteria
CJO35_21585	COG3949	Membrane
CJO35_21595	COG1475	DNA binding
CJO35_21600	COG1192	Involved in chromosome partitioning
CJO35_21605	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO35_21615	COG1475	DNA binding
CJO35_21620	COG0357	Ribosomal RNA small subunit methyltransferase G
CJO35_21625	COG0445	tRNA wobble uridine modification
CJO35_21630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJO35_21635	COG1847	R3H domain protein
CJO35_21640	COG0706	membrane insertase activity
CJO35_21645	COG0594	ribonuclease P activity
CJO35_21650	COG0230	Belongs to the bacterial ribosomal protein bL34 family