locus-tag	class	description
GD442_00010	COG0592	DNA-directed DNA polymerase activity
GD442_00015	COG2501	S4 domain
GD442_00025	COG0187	DNA topoisomerase II activity
GD442_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GD442_00065	COG0516	GMP reductase activity
GD442_00065	COG0517	IMP dehydrogenase activity
GD442_00070	COG1686	Belongs to the peptidase S11 family
GD442_00100	COG1428	Deoxynucleoside kinase
GD442_00105	COG1428	Deoxynucleoside kinase
GD442_00110	COG1335	isochorismatase
GD442_00115	COG0590	tRNA wobble adenosine to inosine editing
GD442_00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GD442_00180	COG1982	Orn Lys Arg decarboxylase major
GD442_00190	COG0470	DNA polymerase III
GD442_00195	COG1774	PSP1 C-terminal conserved region
GD442_00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GD442_00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GD442_00220	COG2002	toxin-antitoxin pair type II binding
GD442_00230	COG0084	hydrolase, TatD family'
GD442_00250	COG4466	Protein conserved in bacteria
GD442_00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GD442_00270	COG0251	oxidation-reduction process
GD442_00285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GD442_00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GD442_00305	COG2002	toxin-antitoxin pair type II binding
GD442_00310	COG2244	polysaccharide biosynthetic process
GD442_00315	COG3956	TIGRFAM MazG family protein
GD442_00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GD442_00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GD442_00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GD442_00395	COG0512	Glutamine amidotransferase of anthranilate synthase
GD442_00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GD442_00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GD442_00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GD442_00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GD442_00420	COG1396	sequence-specific DNA binding
GD442_00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GD442_00515	COG3880	PFAM UvrB UvrC protein
GD442_00525	COG0542	response to heat
GD442_00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GD442_00540	COG4956	integral membrane protein (PIN domain superfamily)
GD442_00560	COG1045	serine acetyltransferase
GD442_00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GD442_00580	COG3688	RNA-binding protein containing a PIN domain
GD442_00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GD442_00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GD442_00600	COG0250	Participates in transcription elongation, termination and antitermination
GD442_00625	COG2813	Specifically methylates the guanine in position
GD442_00640	COG1358	cellular component organization or biogenesis
GD442_00745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GD442_00770	COG0201	protein transport
GD442_00780	COG0024	Methionine aminopeptidase
GD442_00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GD442_00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GD442_00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
GD442_00855	COG0489	protein tyrosine kinase activity
GD442_00865	COG2194	sulfuric ester hydrolase activity
GD442_00870	COG0726	polysaccharide deacetylase
GD442_00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GD442_00955	COG4856	YbbR-like protein
GD442_01005	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_01010	COG2011	ABC-type metal ion transport system permease component
GD442_01015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GD442_01020	COG1464	Belongs to the NlpA lipoprotein family
GD442_01035	COG0277	FAD linked oxidase domain protein
GD442_01040	COG2271	Major facilitator Superfamily
GD442_01050	COG2814	Major facilitator Superfamily
GD442_01070	COG2207	Transcriptional regulator
GD442_01085	COG4166	transmembrane transport
GD442_01090	COG4166	transmembrane transport
GD442_01095	COG0656	L-ascorbic acid biosynthetic process
GD442_01115	COG4149	molybdate abc transporter
GD442_01120	COG0725	ABC transporter, periplasmic molybdate-binding protein
GD442_01125	COG1910	domain protein
GD442_01140	COG0697	spore germination
GD442_01155	COG0204	Acyl-transferase
GD442_01165	COG1609	Transcriptional regulator
GD442_01175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_01190	COG5298	Protein conserved in bacteria
GD442_01210	COG0488	(ABC) transporter
GD442_01220	COG0747	negative chemotaxis
GD442_01225	COG0601	transmembrane transport
GD442_01235	COG0444	Belongs to the ABC transporter superfamily
GD442_01240	COG4608	Belongs to the ABC transporter superfamily
GD442_01245	COG0561	phosphatase activity
GD442_01270	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GD442_01275	COG0179	Fumarylacetoacetate (FAA) hydrolase
GD442_01285	COG0531	amino acid
GD442_01290	COG2814	Major facilitator Superfamily
GD442_01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GD442_01310	COG4294	response to UV
GD442_01315	COG0705	Rhomboid family
GD442_01325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GD442_01330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GD442_01335	COG0864	Transcriptional regulator
GD442_01340	COG2337	Toxic component of a toxin-antitoxin (TA) module
GD442_01345	COG2183	response to ionizing radiation
GD442_01445	COG0802	atpase or kinase
GD442_01450	COG1214	PFAM Peptidase M22, glycoprotease
GD442_01455	COG0456	acetyltransferase
GD442_01465	COG0488	(ABC) transporter
GD442_01480	COG1266	CAAX protease self-immunity
GD442_01500	COG2252	PERMEase
GD442_01510	COG5002	protein histidine kinase activity
GD442_01535	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GD442_01575	COG2205	protein histidine kinase activity
GD442_01580	COG0745	RESPONSE REGULATOR receiver
GD442_01610	COG2226	methyltransferase
GD442_01620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GD442_01630	COG1215	transferase activity, transferring glycosyl groups
GD442_01650	COG0697	spore germination
GD442_01680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GD442_01685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GD442_01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GD442_01700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GD442_01715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GD442_01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GD442_01735	COG0151	Belongs to the GarS family
GD442_01760	COG0210	DNA helicase
GD442_01770	COG4851	CamS sex pheromone cAM373 precursor
GD442_01785	COG1335	isochorismatase
GD442_01795	COG2011	ABC-type metal ion transport system permease component
GD442_01800	COG1464	Belongs to the NlpA lipoprotein family
GD442_01815	COG0003	Pfam Anion-transporting ATPase
GD442_01820	COG1846	Transcriptional regulator
GD442_01825	COG4682	membrane
GD442_01845	COG1597	lipid kinase activity
GD442_01855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GD442_01865	COG1012	belongs to the aldehyde dehydrogenase family
GD442_01870	COG2076	Multidrug Resistance protein
GD442_01880	COG2309	aminopeptidase activity
GD442_01895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GD442_01905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GD442_01910	COG4807	Protein conserved in bacteria
GD442_01940	COG1473	amidohydrolase
GD442_01960	COG0450	alkyl hydroperoxide reductase
GD442_01965	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GD442_01975	COG0235	Class ii aldolase
GD442_01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_01985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_01990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_02005	COG0166	Belongs to the GPI family
GD442_02030	COG5002	protein histidine kinase activity
GD442_02050	COG3541	Predicted nucleotidyltransferase
GD442_02060	COG0723	plastoquinol--plastocyanin reductase activity
GD442_02060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GD442_02070	COG0765	amino acid transport
GD442_02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GD442_02080	COG1126	abc transporter atp-binding protein
GD442_02085	COG0840	transmembrane signaling receptor activity
GD442_02110	COG0549	Belongs to the carbamate kinase family
GD442_02115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GD442_02125	COG0277	FAD linked oxidase domain protein
GD442_02130	COG0366	Alpha amylase catalytic
GD442_02135	COG2190	(PTS) system
GD442_02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GD442_02135	COG1263	PTS System
GD442_02165	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GD442_02185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GD442_02190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GD442_02195	COG1116	anion transmembrane transporter activity
GD442_02200	COG0488	(ABC) transporter
GD442_02245	COG2270	Major facilitator Superfamily
GD442_02275	COG2310	stress, protein
GD442_02280	COG2310	stress, protein
GD442_02285	COG2310	stress, protein
GD442_02290	COG0861	Integral membrane protein TerC family
GD442_02300	COG3853	Toxic anion resistance protein (TelA)
GD442_02315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GD442_02325	COG1295	ribonuclease BN
GD442_02330	COG2217	Heavy metal translocating P-type atpase
GD442_02335	COG0697	spore germination
GD442_02345	COG0681	Belongs to the peptidase S26 family
GD442_02355	COG0586	Pfam SNARE associated Golgi protein
GD442_02370	COG3871	stress protein (general stress protein 26)
GD442_02375	COG0387	Pfam Sodium calcium exchanger
GD442_02385	COG0535	radical SAM domain protein
GD442_02405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GD442_02410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GD442_02425	COG3829	transcription factor binding
GD442_02435	COG0833	amino acid
GD442_02440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GD442_02465	COG1263	PTS System
GD442_02465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GD442_02470	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GD442_02485	COG0463	Glycosyl transferase, family 2
GD442_02495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GD442_02495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GD442_02515	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GD442_02535	COG1228	amidohydrolase
GD442_02540	COG1090	epimerase
GD442_02570	COG1988	membrane-bound metal-dependent
GD442_02575	COG1194	a g-specific adenine glycosylase
GD442_02600	COG1132	(ABC) transporter
GD442_02605	COG4129	membrane
GD442_02610	COG0067	glutamate synthase
GD442_02610	COG0070	glutamate synthase
GD442_02610	COG0069	glutamate synthase activity
GD442_02620	COG4555	ABC transporter
GD442_02640	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GD442_02645	COG0735	belongs to the Fur family
GD442_02765	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GD442_02790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GD442_02800	COG2766	serine protein kinase
GD442_02820	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GD442_02830	COG1585	Membrane protein implicated in regulation of membrane protease activity
GD442_02835	COG2268	Band 7 protein
GD442_02845	COG3290	protein histidine kinase activity
GD442_02850	COG4565	transcriptional regulatory protein
GD442_02855	COG2851	Citrate transporter
GD442_02880	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GD442_02885	COG3842	ATPase activity
GD442_02890	COG1175	transmembrane transport
GD442_02895	COG0395	ABC-type sugar transport system, permease component
GD442_02905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GD442_02910	COG0745	RESPONSE REGULATOR receiver
GD442_02915	COG5002	protein histidine kinase activity
GD442_02925	COG4990	cell redox homeostasis
GD442_02935	COG3290	protein histidine kinase activity
GD442_02940	COG4565	transcriptional regulatory protein
GD442_02945	COG3493	citrate carrier protein
GD442_02950	COG0281	malic enzyme
GD442_02960	COG0697	spore germination
GD442_02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_02975	COG5002	protein histidine kinase activity
GD442_02990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GD442_02995	COG3383	formate dehydrogenase (NAD+) activity
GD442_03000	COG2427	Protein of unknown function (DUF1641)
GD442_03015	COG0531	amino acid
GD442_03025	COG0640	Transcriptional regulator
GD442_03030	COG2217	Heavy metal translocating P-type atpase
GD442_03035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GD442_03050	COG3227	Zinc metalloprotease (Elastase)
GD442_03070	COG2720	vancomycin resistance protein
GD442_03075	COG1316	TRANSCRIPTIONal
GD442_03080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GD442_03085	COG0346	lactoylglutathione lyase activity
GD442_03090	COG1253	flavin adenine dinucleotide binding
GD442_03095	COG1027	Aspartate ammonia-lyase
GD442_03100	COG1620	l-lactate permease
GD442_03115	COG3104	oligopeptide transport
GD442_03120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_03125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_03150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GD442_03160	COG4548	von Willebrand factor, type A
GD442_03165	COG0714	Associated with various cellular activities
GD442_03185	COG0531	amino acid
GD442_03190	COG2188	Transcriptional regulator
GD442_03195	COG1263	PTS System
GD442_03195	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GD442_03200	COG0366	Alpha amylase catalytic
GD442_03215	COG0697	spore germination
GD442_03225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GD442_03230	COG1115	amino acid carrier protein
GD442_03235	COG1126	abc transporter atp-binding protein
GD442_03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GD442_03245	COG0765	amino acid transport
GD442_03250	COG0765	amino acid transport
GD442_03255	COG0833	amino acid
GD442_03280	COG2378	regulation of single-species biofilm formation
GD442_03285	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GD442_03290	COG5002	protein histidine kinase activity
GD442_03305	COG0659	secondary active sulfate transmembrane transporter activity
GD442_03320	COG2271	Major facilitator Superfamily
GD442_03325	COG1846	Transcriptional regulator
GD442_03330	COG0477	Major facilitator Superfamily
GD442_03335	COG1609	Transcriptional regulator
GD442_03340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GD442_03355	COG1172	Belongs to the binding-protein-dependent transport system permease family
GD442_03360	COG1879	ABC-type sugar transport system periplasmic component
GD442_03380	COG1063	alcohol dehydrogenase
GD442_03430	COG0840	transmembrane signaling receptor activity
GD442_03435	COG3584	3D domain protein
GD442_03435	COG3583	domain protein
GD442_03440	COG1476	TRANSCRIPTIONal
GD442_03460	COG3104	oligopeptide transport
GD442_03465	COG1114	Component of the transport system for branched-chain amino acids
GD442_03480	COG1113	amino acid transport
GD442_03485	COG2252	PERMEase
GD442_03510	COG2153	protein acetylation
GD442_03520	COG0475	glutathione-regulated potassium exporter activity
GD442_03520	COG0569	domain protein
GD442_03535	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GD442_03545	COG0833	amino acid
GD442_03550	COG4990	cell redox homeostasis
GD442_03565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GD442_03570	COG0697	spore germination
GD442_03575	COG0531	amino acid
GD442_03585	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GD442_03590	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GD442_03595	COG1918	ferrous iron import across plasma membrane
GD442_03595	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GD442_03600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GD442_03605	COG0573	inorganic phosphate transmembrane transporter activity
GD442_03610	COG0581	inorganic phosphate transmembrane transporter activity
GD442_03620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GD442_03740	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GD442_03760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GD442_03765	COG1116	anion transmembrane transporter activity
GD442_03770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GD442_03775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GD442_03780	COG0352	thiamine-phosphate diphosphorylase activity
GD442_03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GD442_03790	COG2104	thiamine diphosphate biosynthetic process
GD442_03800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GD442_03805	COG0351	phosphomethylpyrimidine kinase
GD442_03845	COG2205	protein histidine kinase activity
GD442_03850	COG2814	Major facilitator Superfamily
GD442_03855	COG1846	Transcriptional regulator
GD442_03880	COG1136	(ABC) transporter
GD442_03895	COG1172	Belongs to the binding-protein-dependent transport system permease family
GD442_03900	COG1129	ABC transporter
GD442_03910	COG2252	PERMEase
GD442_03915	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_03930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GD442_03935	COG1621	beta-fructofuranosidase activity
GD442_03940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GD442_03940	COG1263	PTS System
GD442_03945	COG1609	Transcriptional regulator
GD442_03995	COG0778	Nitroreductase
GD442_04000	COG2719	SpoVR family
GD442_04010	COG1414	Transcriptional regulator
GD442_04025	COG0446	pyridine nucleotide-disulphide oxidoreductase
GD442_04030	COG1937	Protein conserved in bacteria
GD442_04035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GD442_04035	COG0425	Belongs to the sulfur carrier protein TusA family
GD442_04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GD442_04040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_04045	COG0425	Belongs to the sulfur carrier protein TusA family
GD442_04050	COG0425	Belongs to the sulfur carrier protein TusA family
GD442_04050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GD442_04055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GD442_04060	COG2210	Belongs to the sulfur carrier protein TusA family
GD442_04065	COG0730	response to heat
GD442_04075	COG1316	TRANSCRIPTIONal
GD442_04080	COG0604	alcohol dehydrogenase
GD442_04085	COG1283	sodium-dependent phosphate transmembrane transporter activity
GD442_04100	COG3711	transcriptional antiterminator
GD442_04100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GD442_04105	COG1447	Phosphotransferase system cellobiose-specific component IIA
GD442_04110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GD442_04135	COG3584	3D domain protein
GD442_04135	COG1388	LysM domain
GD442_04140	COG0577	efflux transmembrane transporter activity
GD442_04145	COG1136	(ABC) transporter
GD442_04155	COG5522	Integral membrane protein (intg_mem_TP0381)
GD442_04170	COG1114	Component of the transport system for branched-chain amino acids
GD442_04175	COG3546	catalase activity
GD442_04210	COG0586	Pfam SNARE associated Golgi protein
GD442_04240	COG0531	amino acid
GD442_04245	COG0475	glutathione-regulated potassium exporter activity
GD442_04255	COG1737	Transcriptional regulator
GD442_04265	COG1263	PTS System
GD442_04265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GD442_04275	COG2259	Doxx family
GD442_04295	COG1522	sequence-specific DNA binding
GD442_04300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GD442_04300	COG0165	Argininosuccinate lyase
GD442_04305	COG0300	oxidoreductase activity
GD442_04315	COG2076	Multidrug Resistance protein
GD442_04325	COG1309	transcriptional regulator
GD442_04330	COG2814	Major facilitator Superfamily
GD442_04335	COG1733	regulation of RNA biosynthetic process
GD442_04375	COG0693	protein deglycase activity
GD442_04380	COG0693	protein deglycase activity
GD442_04380	COG0753	catalase activity
GD442_04390	COG0531	amino acid
GD442_04395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GD442_04405	COG1012	belongs to the aldehyde dehydrogenase family
GD442_04410	COG1132	(ABC) transporter
GD442_04415	COG1132	(ABC) transporter
GD442_04420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GD442_04425	COG0765	amino acid transport
GD442_04430	COG1126	abc transporter atp-binding protein
GD442_04445	COG0189	ligase activity
GD442_04475	COG0028	Belongs to the TPP enzyme family
GD442_04480	COG3527	Alpha-acetolactate decarboxylase
GD442_04490	COG0561	phosphatase activity
GD442_04500	COG5632	N-Acetylmuramoyl-L-alanine amidase
GD442_04500	COG3409	Peptidoglycan-binding domain 1 protein
GD442_04505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GD442_04510	COG0318	PFAM AMP-dependent synthetase and ligase
GD442_04525	COG0659	secondary active sulfate transmembrane transporter activity
GD442_04530	COG2244	polysaccharide biosynthetic process
GD442_04550	COG1024	Enoyl-CoA hydratase
GD442_04570	COG1363	Peptidase, m42
GD442_04605	COG0601	transmembrane transport
GD442_04610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GD442_04615	COG0444	Belongs to the ABC transporter superfamily
GD442_04620	COG4608	Belongs to the ABC transporter superfamily
GD442_04645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_04730	COG0477	Major facilitator Superfamily
GD442_04735	COG3290	protein histidine kinase activity
GD442_04740	COG4565	transcriptional regulatory protein
GD442_04745	COG3181	Tripartite tricarboxylate transporter family receptor
GD442_04785	COG0305	Participates in initiation and elongation during chromosome replication
GD442_04805	COG0477	Major facilitator Superfamily
GD442_04820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_04840	COG1073	alpha beta
GD442_04880	COG1183	phosphatidylcholine synthase activity
GD442_04900	COG2376	Dihydroxyacetone kinase
GD442_04910	COG2376	Dihydroxyacetone kinase
GD442_04940	COG1388	LysM domain
GD442_04940	COG3584	3D domain protein
GD442_04945	COG0791	NLP P60 protein
GD442_04945	COG1388	LysM domain
GD442_04950	COG2373	Large extracellular alpha-helical protein
GD442_04975	COG0596	Alpha beta hydrolase
GD442_05025	COG1191	sigma factor activity
GD442_05035	COG2208	phosphoserine phosphatase activity
GD442_05040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GD442_05045	COG0784	Response regulator, receiver
GD442_05045	COG5002	protein histidine kinase activity
GD442_05045	COG2205	protein histidine kinase activity
GD442_05065	COG0393	Putative heavy-metal-binding
GD442_05080	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GD442_05100	COG0420	3'-5' exonuclease activity
GD442_05105	COG4717	serine-type aminopeptidase activity
GD442_05115	COG0346	lactoylglutathione lyase activity
GD442_05120	COG0346	lactoylglutathione lyase activity
GD442_05125	COG0457	Tetratricopeptide repeat
GD442_05135	COG2267	carboxylic ester hydrolase activity
GD442_05155	COG2140	Oxalate decarboxylase
GD442_05160	COG3620	sequence-specific DNA binding
GD442_05165	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GD442_05170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GD442_05180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GD442_05185	COG1695	Transcriptional regulator
GD442_05200	COG3973	AAA domain
GD442_05230	COG4980	gas vesicle protein
GD442_05235	COG0537	adenosine 5'-monophosphoramidase activity
GD442_05240	COG1131	(ABC) transporter
GD442_05245	COG4473	ABC transporter
GD442_05265	COG3402	PFAM membrane-flanked domain
GD442_05270	COG3428	Bacterial PH domain
GD442_05305	COG0697	spore germination
GD442_05310	COG3402	PFAM membrane-flanked domain
GD442_05315	COG3428	Bacterial PH domain
GD442_05320	COG2329	Antibiotic biosynthesis monooxygenase
GD442_05325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GD442_05375	COG1309	transcriptional regulator
GD442_05380	COG1511	domain protein
GD442_05380	COG1511	domain protein
GD442_05395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_05400	COG1609	Transcriptional regulator
GD442_05410	COG1234	tRNA 3'-trailer cleavage
GD442_05415	COG0095	Lipoate-protein ligase
GD442_05425	COG0318	PFAM AMP-dependent synthetase and ligase
GD442_05435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GD442_05445	COG4208	sulfate ABC transporter
GD442_05510	COG1408	metallophosphoesterase
GD442_05515	COG1078	dGTPase activity
GD442_05525	COG1595	DNA-templated transcription, initiation
GD442_05530	COG2207	Transcriptional regulator
GD442_05530	COG3708	Transcriptional regulator
GD442_05535	COG2205	protein histidine kinase activity
GD442_05540	COG0745	RESPONSE REGULATOR receiver
GD442_05560	COG0501	Belongs to the peptidase M48B family
GD442_05565	COG0840	transmembrane signaling receptor activity
GD442_05570	COG3693	PFAM glycoside hydrolase, family 10
GD442_05580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GD442_05585	COG2224	Isocitrate lyase
GD442_05600	COG1278	Cold shock
GD442_05620	COG0398	Pfam SNARE associated Golgi protein
GD442_05680	COG0179	Fumarylacetoacetate (FAA) hydrolase
GD442_05705	COG0367	asparagine synthase
GD442_05715	COG0753	catalase activity
GD442_05720	COG0004	ammonium transporteR
GD442_05740	COG2996	Protein conserved in bacteria
GD442_05755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_05770	COG0561	phosphatase activity
GD442_05790	COG2267	carboxylic ester hydrolase activity
GD442_05810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GD442_05815	COG5504	Zn-dependent protease
GD442_05825	COG0180	Tryptophanyl-tRNA synthetase
GD442_05835	COG4166	transmembrane transport
GD442_05840	COG0601	transmembrane transport
GD442_05845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GD442_05850	COG0444	Belongs to the ABC transporter superfamily
GD442_05855	COG4608	Belongs to the ABC transporter superfamily
GD442_05860	COG0534	Mate efflux family protein
GD442_05865	COG4166	transmembrane transport
GD442_05875	COG1393	Belongs to the ArsC family
GD442_05880	COG0861	Integral membrane protein TerC family
GD442_05900	COG1164	Oligoendopeptidase f
GD442_05910	COG2346	COG2346, Truncated hemoglobins
GD442_05915	COG4116	CYTH
GD442_05925	COG2357	RelA SpoT domain protein
GD442_05935	COG0564	pseudouridine synthase activity
GD442_05950	COG0772	Belongs to the SEDS family
GD442_05955	COG1216	Glycosyl transferase, family 2
GD442_05975	COG0457	Tetratricopeptide repeat
GD442_05975	COG0463	Glycosyl transferase, family 2
GD442_05995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GD442_06010	COG1091	dTDP-4-dehydrorhamnose reductase activity
GD442_06055	COG2153	protein acetylation
GD442_06065	COG2382	esterase
GD442_06085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GD442_06095	COG0512	Glutamine amidotransferase of anthranilate synthase
GD442_06095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GD442_06130	COG1620	l-lactate permease
GD442_06135	COG5634	Uncharacterized conserved protein (DUF2278)
GD442_06185	COG0508	dehydrogenase complex catalyzes the overall conversion of
GD442_06195	COG1476	TRANSCRIPTIONal
GD442_06255	COG1686	Belongs to the peptidase S11 family
GD442_06260	COG0681	Belongs to the peptidase S26 family
GD442_06295	COG1012	belongs to the aldehyde dehydrogenase family
GD442_06305	COG1176	ABC-type spermidine putrescine transport system, permease component I
GD442_06310	COG1177	transmembrane transport
GD442_06315	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GD442_06325	COG2409	Drug exporters of the RND superfamily
GD442_06335	COG0564	pseudouridine synthase activity
GD442_06345	COG2340	Cysteine-rich secretory protein family
GD442_06350	COG0247	lactate metabolic process
GD442_06355	COG0277	FAD linked oxidase domain protein
GD442_06360	COG3835	regulator
GD442_06370	COG0745	RESPONSE REGULATOR receiver
GD442_06375	COG5002	protein histidine kinase activity
GD442_06380	COG2186	Transcriptional regulator
GD442_06400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GD442_06410	COG2116	formate transmembrane transporter activity
GD442_06415	COG0861	Integral membrane protein TerC family
GD442_06420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GD442_06430	COG2030	dehydratase
GD442_06450	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_06455	COG3243	poly(R)-hydroxyalkanoic acid synthase
GD442_06465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GD442_06475	COG1840	ABC-type Fe3 transport system, periplasmic component
GD442_06480	COG3842	ATPase activity
GD442_06505	COG1349	DNA-binding transcription factor activity
GD442_06515	COG0235	Class ii aldolase
GD442_06525	COG2861	carbohydrate metabolic process
GD442_06535	COG3852	Histidine kinase
GD442_06540	COG1846	Transcriptional regulator
GD442_06550	COG2318	DinB family
GD442_06555	COG5002	protein histidine kinase activity
GD442_06565	COG0720	synthase
GD442_06580	COG4873	Protein conserved in bacteria
GD442_06605	COG1780	Probably involved in ribonucleotide reductase function
GD442_06625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GD442_06630	COG1725	Transcriptional regulator
GD442_06635	COG1131	(ABC) transporter
GD442_06645	COG1131	(ABC) transporter
GD442_06665	COG1522	sequence-specific DNA binding
GD442_06675	COG1335	isochorismatase
GD442_06685	COG1619	proteins homologs of microcin C7 resistance protein MccF
GD442_06690	COG2070	2-Nitropropane dioxygenase
GD442_06695	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GD442_06705	COG1696	Membrane protein involved in D-alanine export
GD442_06725	COG0716	FMN binding
GD442_06735	COG3173	Aminoglycoside phosphotransferase
GD442_06770	COG1846	Transcriptional regulator
GD442_06780	COG1301	dicarboxylic acid transport
GD442_06785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GD442_06790	COG4709	membrane
GD442_06795	COG3874	Sporulation protein YtfJ
GD442_06815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GD442_06820	COG0028	Belongs to the TPP enzyme family
GD442_06825	COG0440	acetolactate synthase activity
GD442_06900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GD442_06915	COG1183	phosphatidylcholine synthase activity
GD442_06920	COG1368	sulfuric ester hydrolase activity
GD442_06930	COG0019	diaminopimelate decarboxylase activity
GD442_06950	COG0529	Catalyzes the synthesis of activated sulfate
GD442_06955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GD442_06975	COG1648	precorrin-2 dehydrogenase activity
GD442_06980	COG0733	neurotransmitter:sodium symporter activity
GD442_07000	COG1757	Na H antiporter
GD442_07015	COG4758	membrane
GD442_07020	COG4585	Histidine kinase
GD442_07025	COG2197	response regulator
GD442_07035	COG1114	Component of the transport system for branched-chain amino acids
GD442_07085	COG0730	response to heat
GD442_07090	COG0306	phosphate transporter
GD442_07095	COG1392	Phosphate transport regulator
GD442_07100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GD442_07115	COG3852	Histidine kinase
GD442_07120	COG1801	Protein of unknown function DUF72
GD442_07130	COG0582	viral genome integration into host DNA
GD442_07135	COG5002	protein histidine kinase activity
GD442_07150	COG0392	lysyltransferase activity
GD442_07150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GD442_07165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GD442_07170	COG1686	Belongs to the peptidase S11 family
GD442_07175	COG2715	membrane protein required for spore maturation
GD442_07180	COG0700	Nucleoside recognition
GD442_07185	COG1187	pseudouridine synthase activity
GD442_07195	COG1333	cytochrome c biogenesis protein
GD442_07200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GD442_07205	COG0745	RESPONSE REGULATOR receiver
GD442_07210	COG5002	protein histidine kinase activity
GD442_07215	COG2096	Adenosyltransferase
GD442_07230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GD442_07235	COG1141	Ferredoxin
GD442_07245	COG0514	ATP-dependent DNA helicase (RecQ)
GD442_07250	COG1266	CAAX protease self-immunity
GD442_07260	COG1408	metallophosphoesterase
GD442_07265	COG0789	Transcriptional regulator
GD442_07275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GD442_07295	COG0492	ferredoxin-NADP+ reductase activity
GD442_07300	COG0252	asparaginase activity
GD442_07365	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GD442_07380	COG0142	geranyltranstransferase activity
GD442_07390	COG0142	geranyltranstransferase activity
GD442_07415	COG0457	Tetratricopeptide repeat
GD442_07435	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GD442_07440	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GD442_07440	COG2010	Cytochrome c
GD442_07445	COG4347	Protein of unknown function (DUF1405)
GD442_07460	COG2738	Putative neutral zinc metallopeptidase
GD442_07470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_07475	COG1694	Mazg nucleotide pyrophosphohydrolase
GD442_07495	COG0438	transferase activity, transferring glycosyl groups
GD442_07530	COG1199	ATP-dependent helicase activity
GD442_07530	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GD442_07550	COG3935	DnaD domain protein
GD442_07555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GD442_07565	COG4499	WXG100 protein secretion system (Wss), protein YukC
GD442_07565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GD442_07620	COG0116	Belongs to the methyltransferase superfamily
GD442_07630	COG1199	ATP-dependent helicase activity
GD442_07635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GD442_07645	COG0024	Methionine aminopeptidase
GD442_07655	COG2233	PERMEase
GD442_07660	COG2311	Membrane
GD442_07670	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GD442_07680	COG0456	acetyltransferase
GD442_07730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GD442_07745	COG3944	biosynthesis protein
GD442_07755	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GD442_07770	COG1215	transferase activity, transferring glycosyl groups
GD442_07775	COG0438	transferase activity, transferring glycosyl groups
GD442_07790	COG0454	-acetyltransferase
GD442_07810	COG0328	RNA-DNA hybrid ribonuclease activity
GD442_07845	COG3403	YqcI/YcgG family
GD442_07850	COG1280	lysine exporter protein (LysE YggA)
GD442_07870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GD442_07875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GD442_07885	COG0475	glutathione-regulated potassium exporter activity
GD442_07890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GD442_07895	COG0789	Transcriptional regulator
GD442_07895	COG4978	Transcriptional regulator
GD442_07905	COG2323	membrane
GD442_07910	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GD442_07955	COG1923	regulation of RNA biosynthetic process
GD442_07965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GD442_07970	COG1360	Flagellar Motor Protein
GD442_07975	COG2201	protein-glutamate methylesterase activity
GD442_07980	COG0643	Histidine kinase
GD442_07980	COG2198	Histidine kinase
GD442_07985	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GD442_07985	COG1776	CheC inhibitor of MCP methylation
GD442_08000	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GD442_08020	COG1256	bacterial-type flagellum assembly
GD442_08025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GD442_08030	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GD442_08045	COG1815	bacterial-type flagellum-dependent cell motility
GD442_08050	COG1558	bacterial-type flagellum-dependent cell motility
GD442_08055	COG1677	Flagellar hook-basal body complex protein FliE
GD442_08060	COG1766	The M ring may be actively involved in energy transduction
GD442_08065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GD442_08075	COG1157	protein secretion by the type III secretion system
GD442_08095	COG1749	Flagellar hook protein flgE
GD442_08110	COG0784	Response regulator, receiver
GD442_08110	COG0835	chemotaxis
GD442_08120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GD442_08125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GD442_08130	COG0741	lytic transglycosylase activity
GD442_08140	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GD442_08145	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GD442_08145	COG1776	CheC inhibitor of MCP methylation
GD442_08155	COG1338	Plays a role in the flagellum-specific transport system
GD442_08160	COG1987	bacterial-type flagellum assembly
GD442_08170	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GD442_08175	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GD442_08180	COG1419	protein localization to endoplasmic reticulum
GD442_08185	COG4786	Flagellar basal body rod
GD442_08190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GD442_08225	COG2329	Antibiotic biosynthesis monooxygenase
GD442_08265	COG1177	transmembrane transport
GD442_08270	COG1234	tRNA 3'-trailer cleavage
GD442_08300	COG0406	alpha-ribazole phosphatase activity
GD442_08330	COG0367	asparagine synthase
GD442_08360	COG1802	Transcriptional regulator
GD442_08365	COG0697	spore germination
GD442_08375	COG0523	cobalamin synthesis protein
GD442_08380	COG0701	Predicted permease
GD442_08395	COG1757	Na H antiporter
GD442_08400	COG0789	Transcriptional regulator
GD442_08425	COG0534	Mate efflux family protein
GD442_08430	COG3340	Belongs to the peptidase S51 family
GD442_08450	COG0785	Cytochrome C biogenesis protein
GD442_08455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD442_08465	COG0457	Tetratricopeptide repeat
GD442_08485	COG2733	membrane
GD442_08520	COG1131	(ABC) transporter
GD442_08535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GD442_08540	COG0528	UMP kinase activity
GD442_08550	COG1027	Aspartate ammonia-lyase
GD442_08555	COG0281	malic enzyme
GD442_08560	COG4191	Histidine kinase
GD442_08565	COG0784	Response regulator, receiver
GD442_08570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GD442_08625	COG1695	Transcriptional regulator
GD442_08635	COG0477	Major facilitator Superfamily
GD442_08645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GD442_08650	COG2223	nitrite transmembrane transporter activity
GD442_08655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GD442_08675	COG0733	neurotransmitter:sodium symporter activity
GD442_08685	COG5566	PFAM Mor transcription activator
GD442_08690	COG2323	membrane
GD442_08710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GD442_08720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GD442_08725	COG0028	Belongs to the TPP enzyme family
GD442_08745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GD442_08770	COG2814	Major facilitator Superfamily
GD442_08775	COG3384	dioxygenase
GD442_08785	COG3279	Response regulator of the LytR AlgR family
GD442_08790	COG0427	acetyl-CoA hydrolase
GD442_08810	COG4166	transmembrane transport
GD442_08815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_08820	COG1914	H( )-stimulated, divalent metal cation uptake system
GD442_08835	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GD442_08840	COG0531	amino acid
GD442_08870	COG2309	aminopeptidase activity
GD442_08885	COG0456	acetyltransferase
GD442_08900	COG1309	transcriptional regulator
GD442_08905	COG2390	Transcriptional regulator
GD442_08915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GD442_08920	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GD442_08930	COG4846	Membrane protein involved in cytochrome C biogenesis
GD442_08950	COG0583	DNA-binding transcription factor activity
GD442_08965	COG0006	proline dipeptidase activity
GD442_08975	COG2132	Multicopper oxidase
GD442_09005	COG1114	Component of the transport system for branched-chain amino acids
GD442_09015	COG2372	response to copper ion
GD442_09015	COG1276	copper resistance
GD442_09020	COG4549	nuclear export factor GLE1
GD442_09025	COG0697	spore germination
GD442_09030	COG0583	DNA-binding transcription factor activity
GD442_09035	COG1959	2 iron, 2 sulfur cluster binding
GD442_09040	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GD442_09045	COG0778	Nitroreductase
GD442_09055	COG0628	permease
GD442_09065	COG1231	oxidoreductase activity
GD442_09070	COG0523	cobalamin synthesis protein
GD442_09080	COG0411	ABC transporter
GD442_09090	COG0559	Belongs to the binding-protein-dependent transport system permease family
GD442_09100	COG0583	DNA-binding transcription factor activity
GD442_09110	COG1942	4-Oxalocrotonate Tautomerase
GD442_09130	COG1271	oxidase subunit
GD442_09135	COG1294	oxidase, subunit
GD442_09140	COG4988	ABC transporter
GD442_09145	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GD442_09155	COG1216	Glycosyl transferase, family 2
GD442_09195	COG1686	Belongs to the peptidase S11 family
GD442_09210	COG0791	NLP P60 protein
GD442_09210	COG1388	LysM domain
GD442_09220	COG1132	(ABC) transporter
GD442_09225	COG0745	RESPONSE REGULATOR receiver
GD442_09230	COG5002	protein histidine kinase activity
GD442_09235	COG0300	oxidoreductase activity
GD442_09245	COG0726	polysaccharide deacetylase
GD442_09265	COG0460	homoserine dehydrogenase
GD442_09290	COG1316	TRANSCRIPTIONal
GD442_09300	COG0745	RESPONSE REGULATOR receiver
GD442_09305	COG5002	protein histidine kinase activity
GD442_09310	COG0726	polysaccharide deacetylase
GD442_09320	COG1285	pathogenesis
GD442_09325	COG1247	-acetyltransferase
GD442_09335	COG4264	IucA IucC family
GD442_09340	COG0318	PFAM AMP-dependent synthetase and ligase
GD442_09355	COG1082	Xylose isomerase domain protein TIM barrel
GD442_09365	COG2814	Major facilitator Superfamily
GD442_09370	COG1279	arginine transmembrane transporter activity
GD442_09375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_09385	COG1752	Esterase of the alpha-beta hydrolase superfamily
GD442_09420	COG0577	efflux transmembrane transporter activity
GD442_09425	COG2002	toxin-antitoxin pair type II binding
GD442_09430	COG1404	Belongs to the peptidase S8 family
GD442_09445	COG3152	Membrane
GD442_09470	COG0840	transmembrane signaling receptor activity
GD442_09485	COG3949	Membrane
GD442_09490	COG0783	Belongs to the Dps family
GD442_09505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GD442_09515	COG1231	oxidoreductase activity
GD442_09520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_09525	COG4989	oxidoreductase activity
GD442_09530	COG0523	cobalamin synthesis protein
GD442_09535	COG0456	acetyltransferase
GD442_09540	COG0803	Belongs to the bacterial solute-binding protein 9 family
GD442_09545	COG0702	epimerase
GD442_09555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GD442_09565	COG4166	transmembrane transport
GD442_09590	COG5337	Spore coat protein CotH
GD442_09595	COG1051	belongs to the nudix hydrolase family
GD442_09600	COG0586	Pfam SNARE associated Golgi protein
GD442_09605	COG2244	polysaccharide biosynthetic process
GD442_09615	COG0701	Predicted permease
GD442_09620	COG3689	TIGRFAM TIGR03943 family protein
GD442_09625	COG1607	acyl-coa hydrolase
GD442_09635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GD442_09650	COG0702	epimerase
GD442_09655	COG2839	Protein conserved in bacteria
GD442_09660	COG1253	flavin adenine dinucleotide binding
GD442_09675	COG1114	Component of the transport system for branched-chain amino acids
GD442_09680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GD442_09700	COG0860	N-Acetylmuramoyl-L-alanine amidase
GD442_09710	COG1876	peptidase activity
GD442_09720	COG0154	amidase activity
GD442_09725	COG2211	Major facilitator Superfamily
GD442_09740	COG0860	N-Acetylmuramoyl-L-alanine amidase
GD442_09750	COG0561	phosphatase activity
GD442_09755	COG1846	Transcriptional regulator
GD442_09760	COG2814	Major facilitator Superfamily
GD442_09770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GD442_09780	COG1819	glycosyl
GD442_09785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_09790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_09820	COG0456	acetyltransferase
GD442_09840	COG0842	Transport permease protein
GD442_09840	COG1511	domain protein
GD442_09855	COG4499	WXG100 protein secretion system (Wss), protein YukC
GD442_09935	COG3646	Phage regulatory protein
GD442_09935	COG3645	SOS response
GD442_09985	COG4974	Belongs to the 'phage' integrase family
GD442_09995	COG3874	Sporulation protein YtfJ
GD442_10020	COG2226	methyltransferase
GD442_10045	COG0346	lactoylglutathione lyase activity
GD442_10055	COG0604	alcohol dehydrogenase
GD442_10060	COG1595	DNA-templated transcription, initiation
GD442_10075	COG0426	domain, Protein
GD442_10075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GD442_10085	COG0386	Belongs to the glutathione peroxidase family
GD442_10090	COG1305	Transglutaminase-like
GD442_10095	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GD442_10100	COG0714	Associated with various cellular activities
GD442_10105	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GD442_10110	COG1140	nitrate reductase beta subunit
GD442_10115	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
GD442_10120	COG2181	nitrate reductase activity
GD442_10125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GD442_10130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GD442_10135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GD442_10140	COG0303	'Molybdopterin
GD442_10145	COG0314	molybdopterin synthase activity
GD442_10155	COG2223	nitrite transmembrane transporter activity
GD442_10175	COG1648	precorrin-2 dehydrogenase activity
GD442_10185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GD442_10185	COG1587	Uroporphyrinogen-III synthase
GD442_10190	COG2146	nitrite reductase [NAD(P)H] activity
GD442_10195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GD442_10200	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GD442_10235	COG2359	stage V sporulation protein S
GD442_10260	COG0457	Tetratricopeptide repeat
GD442_10275	COG1418	mRNA catabolic process
GD442_10280	COG0488	(ABC) transporter
GD442_10295	COG0629	single-stranded DNA binding
GD442_10300	COG1413	lyase activity
GD442_10315	COG2521	methyltransferase
GD442_10315	COG2136	Putative SAM-dependent methyltransferase
GD442_10320	COG0018	arginyl-trna synthetase
GD442_10370	COG0017	Asparaginyl-tRNA synthetase
GD442_10375	COG0733	neurotransmitter:sodium symporter activity
GD442_10400	COG2610	gluconate transmembrane transporter activity
GD442_10410	COG1794	racemase activity, acting on amino acids and derivatives
GD442_10420	COG0456	acetyltransferase
GD442_10430	COG3655	Transcriptional regulator
GD442_10435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GD442_10445	COG1131	(ABC) transporter
GD442_10450	COG4473	ABC transporter
GD442_10460	COG0546	phosphoglycolate phosphatase activity
GD442_10475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GD442_10490	COG0768	penicillin binding
GD442_10500	COG0204	Acyl-transferase
GD442_10505	COG1272	protein, Hemolysin III
GD442_10515	COG0805	protein transport
GD442_10525	COG1307	EDD domain protein, DegV family
GD442_10530	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GD442_10535	COG1999	signal sequence binding
GD442_10540	COG0071	Belongs to the small heat shock protein (HSP20) family
GD442_10545	COG0367	asparagine synthase
GD442_10560	COG0860	N-Acetylmuramoyl-L-alanine amidase
GD442_10565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_10570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GD442_10585	COG1335	isochorismatase
GD442_10595	COG0668	transmembrane transport
GD442_10600	COG4585	Histidine kinase
GD442_10600	COG2203	Gaf domain
GD442_10605	COG2197	response regulator
GD442_10610	COG1737	Transcriptional regulator
GD442_10615	COG0384	phenazine biosynthesis protein PhzF
GD442_10620	COG1064	alcohol dehydrogenase
GD442_10645	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GD442_10680	COG0517	IMP dehydrogenase activity
GD442_10680	COG1125	glycine betaine transport
GD442_10685	COG1174	glycine betaine transport
GD442_10720	COG1253	flavin adenine dinucleotide binding
GD442_10725	COG1012	belongs to the aldehyde dehydrogenase family
GD442_10730	COG5506	Protein of unknown function (DUF1694)
GD442_10745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GD442_10750	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GD442_10755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GD442_10760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GD442_10765	COG0456	acetyltransferase
GD442_10770	COG3829	transcription factor binding
GD442_10775	COG1509	lysine 2,3-aminomutase activity
GD442_10810	COG0515	serine threonine protein kinase
GD442_10810	COG3064	Membrane
GD442_10810	COG4991	sh3 domain protein
GD442_10820	COG0671	phosphoesterase, PA-phosphatase related
GD442_10825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GD442_10830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD442_10915	COG0300	oxidoreductase activity
GD442_10935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GD442_10935	COG4499	WXG100 protein secretion system (Wss), protein YukC
GD442_10945	COG2814	Major facilitator Superfamily
GD442_10950	COG4841	protein insertion into membrane
GD442_10955	COG0372	Belongs to the citrate synthase family
GD442_10960	COG2079	MmgE PrpD family protein
GD442_10965	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GD442_10970	COG1960	acyl-CoA dehydrogenase activity
GD442_10975	COG2084	Dehydrogenase
GD442_10985	COG1280	lysine exporter protein (LysE YggA)
GD442_10990	COG1024	Enoyl-CoA hydratase
GD442_11005	COG0420	3'-5' exonuclease activity
GD442_11010	COG0419	ATPase involved in DNA repair
GD442_11030	COG2223	nitrite transmembrane transporter activity
GD442_11035	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_11040	COG1169	isochorismate synthase
GD442_11045	COG1021	2,3-dihydroxybenzoate-AMP ligase
GD442_11050	COG1535	isochorismatase
GD442_11050	COG3433	isochorismatase activity
GD442_11055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GD442_11060	COG3251	PFAM MbtH domain protein
GD442_11065	COG2814	Major facilitator Superfamily
GD442_11080	COG0776	regulation of translation
GD442_11090	COG2318	DinB family
GD442_11100	COG1115	amino acid carrier protein
GD442_11120	COG1187	pseudouridine synthase activity
GD442_11125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GD442_11130	COG1136	(ABC) transporter
GD442_11155	COG0028	Belongs to the TPP enzyme family
GD442_11195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GD442_11215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_11250	COG1247	-acetyltransferase
GD442_11285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_11315	COG0583	DNA-binding transcription factor activity
GD442_11320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GD442_11340	COG0583	DNA-binding transcription factor activity
GD442_11345	COG2258	MOSC domain
GD442_11360	COG1132	(ABC) transporter
GD442_11365	COG1132	(ABC) transporter
GD442_11395	COG1396	sequence-specific DNA binding
GD442_11425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GD442_11430	COG1595	DNA-templated transcription, initiation
GD442_11450	COG1649	PFAM Uncharacterised BCR, COG1649
GD442_11475	COG2971	BadF BadG BcrA BcrD
GD442_11485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GD442_11495	COG1846	Transcriptional regulator
GD442_11515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_11540	COG1309	transcriptional regulator
GD442_11645	COG3615	Tellurite resistance protein tehB
GD442_11645	COG0500	methyltransferase
GD442_11655	COG2226	methyltransferase
GD442_11660	COG3961	Belongs to the TPP enzyme family
GD442_11665	COG1846	Transcriptional regulator
GD442_11695	COG2195	Cleaves the N-terminal amino acid of tripeptides
GD442_11725	COG2002	toxin-antitoxin pair type II binding
GD442_11735	COG0730	response to heat
GD442_11740	COG0110	maltose O-acetyltransferase activity
GD442_11745	COG1686	Belongs to the peptidase S11 family
GD442_11760	COG2814	Major facilitator Superfamily
GD442_11795	COG2312	Erythromycin esterase
GD442_11800	COG0741	lytic transglycosylase activity
GD442_11805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_11840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GD442_11845	COG0768	penicillin binding
GD442_11850	COG1595	DNA-templated transcription, initiation
GD442_11860	COG0768	penicillin binding
GD442_11885	COG1131	(ABC) transporter
GD442_11895	COG1309	transcriptional regulator
GD442_11910	COG1960	acyl-CoA dehydrogenase activity
GD442_11915	COG0439	Biotin carboxylase
GD442_11920	COG0511	ligase activity, forming carbon-carbon bonds
GD442_11925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GD442_11930	COG1024	Enoyl-CoA hydratase
GD442_11935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GD442_11940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GD442_11960	COG0572	uridine kinase
GD442_11980	COG1686	Belongs to the peptidase S11 family
GD442_12005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GD442_12020	COG3227	Zinc metalloprotease (Elastase)
GD442_12025	COG2207	Transcriptional regulator
GD442_12055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GD442_12065	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_12070	COG1733	regulation of RNA biosynthetic process
GD442_12115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_12120	COG2368	4-hydroxyphenylacetate
GD442_12135	COG1063	alcohol dehydrogenase
GD442_12145	COG2323	membrane
GD442_12150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GD442_12160	COG3386	PFAM SMP-30 Gluconolaconase
GD442_12170	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
GD442_12175	COG3773	Cell wall hydrolase
GD442_12180	COG0596	Alpha beta hydrolase
GD442_12190	COG0745	RESPONSE REGULATOR receiver
GD442_12195	COG2205	protein histidine kinase activity
GD442_12220	COG0825	malonyl-CoA metabolic process
GD442_12230	COG1136	(ABC) transporter
GD442_12235	COG0577	efflux transmembrane transporter activity
GD442_12255	COG0460	homoserine dehydrogenase
GD442_12260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_12270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GD442_12325	COG2124	cytochrome p450
GD442_12360	COG0561	phosphatase activity
GD442_12365	COG5002	protein histidine kinase activity
GD442_12380	COG1819	glycosyl
GD442_12385	COG1794	racemase activity, acting on amino acids and derivatives
GD442_12410	COG2205	protein histidine kinase activity
GD442_12425	COG0604	alcohol dehydrogenase
GD442_12430	COG0671	phosphoesterase, PA-phosphatase related
GD442_12480	COG2814	Major facilitator Superfamily
GD442_12485	COG4978	Transcriptional regulator
GD442_12485	COG0789	Transcriptional regulator
GD442_12505	COG0584	glycerophosphoryl diester phosphodiesterase
GD442_12525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_12530	COG0697	spore germination
GD442_12570	COG2223	nitrite transmembrane transporter activity
GD442_12585	COG0592	DNA-directed DNA polymerase activity
GD442_12605	COG3878	Protein conserved in bacteria
GD442_12625	COG4667	esterase of the alpha-beta hydrolase superfamily
GD442_12665	COG0322	excinuclease ABC activity
GD442_12705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GD442_12740	COG0745	RESPONSE REGULATOR receiver
GD442_12745	COG5002	protein histidine kinase activity
GD442_12760	COG1136	(ABC) transporter
GD442_12765	COG0577	efflux transmembrane transporter activity
GD442_12770	COG1073	alpha beta
GD442_12780	COG1523	belongs to the glycosyl hydrolase 13 family
GD442_12785	COG3227	Zinc metalloprotease (Elastase)
GD442_12790	COG0737	Belongs to the 5'-nucleotidase family
GD442_12810	COG0201	protein transport
GD442_12815	COG0697	spore germination
GD442_12820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_12830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GD442_12860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_12875	COG2959	enzyme of heme biosynthesis
GD442_12880	COG3773	Cell wall hydrolase
GD442_12880	COG3409	Peptidoglycan-binding domain 1 protein
GD442_12915	COG1309	transcriptional regulator
GD442_12935	COG3284	Transcriptional regulator
GD442_12950	COG1349	DNA-binding transcription factor activity
GD442_12965	COG1959	2 iron, 2 sulfur cluster binding
GD442_12980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GD442_12985	COG0508	dehydrogenase complex catalyzes the overall conversion of
GD442_12990	COG0022	dehydrogenase e1 component
GD442_12995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GD442_13005	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_13010	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GD442_13010	COG0456	acetyltransferase
GD442_13050	COG4176	ABC-type proline glycine betaine transport system permease component
GD442_13055	COG0517	IMP dehydrogenase activity
GD442_13055	COG4175	Glycine betaine
GD442_13085	COG2153	protein acetylation
GD442_13090	COG3397	chitin binding
GD442_13095	COG1819	glycosyl
GD442_13115	COG2205	protein histidine kinase activity
GD442_13120	COG2226	methyltransferase
GD442_13125	COG2315	Protein conserved in bacteria
GD442_13165	COG0456	acetyltransferase
GD442_13170	COG3973	AAA domain
GD442_13185	COG0514	ATP-dependent DNA helicase (RecQ)
GD442_13215	COG4637	Psort location Cytoplasmic, score
GD442_13230	COG3397	chitin binding
GD442_13245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GD442_13250	COG1115	amino acid carrier protein
GD442_13255	COG1012	belongs to the aldehyde dehydrogenase family
GD442_13260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GD442_13270	COG3938	Belongs to the proline racemase family
GD442_13275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GD442_13315	COG0586	Pfam SNARE associated Golgi protein
GD442_13325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GD442_13335	COG4166	transmembrane transport
GD442_13345	COG4948	Mandelate Racemase Muconate Lactonizing
GD442_13360	COG0667	Aldo Keto reductase
GD442_13405	COG3850	Histidine kinase
GD442_13405	COG5002	protein histidine kinase activity
GD442_13410	COG0745	RESPONSE REGULATOR receiver
GD442_13450	COG1164	Oligoendopeptidase f
GD442_13455	COG1307	EDD domain protein, DegV family
GD442_13495	COG2814	Major facilitator Superfamily
GD442_13505	COG1664	Polymer-forming cytoskeletal
GD442_13510	COG0789	Transcriptional regulator
GD442_13515	COG4533	DNA binding
GD442_13520	COG0477	Major facilitator Superfamily
GD442_13520	COG2814	Major facilitator Superfamily
GD442_13540	COG2261	transglycosylase associated protein
GD442_13555	COG2226	methyltransferase
GD442_13590	COG0436	Aminotransferase
GD442_13595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GD442_13620	COG1131	(ABC) transporter
GD442_13670	COG0628	permease
GD442_13680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GD442_13685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GD442_13690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GD442_13730	COG2746	aminoglycoside 3-N-acetyltransferase activity
GD442_13740	COG0697	spore germination
GD442_13745	COG2318	DinB family
GD442_13765	COG4912	Dna alkylation repair
GD442_13770	COG0346	lactoylglutathione lyase activity
GD442_13775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_13780	COG0726	polysaccharide deacetylase
GD442_13790	COG0861	Integral membrane protein TerC family
GD442_13795	COG1368	sulfuric ester hydrolase activity
GD442_13800	COG0488	(ABC) transporter
GD442_13810	COG2409	Drug exporters of the RND superfamily
GD442_13810	COG1033	growth of symbiont in host cell
GD442_13815	COG1309	transcriptional regulator
GD442_13830	COG0287	Prephenate dehydrogenase
GD442_13845	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GD442_13845	COG1605	Chorismate mutase
GD442_13890	COG3584	3D domain protein
GD442_13890	COG1388	LysM domain
GD442_13900	COG0346	lactoylglutathione lyase activity
GD442_13930	COG1879	ABC-type sugar transport system periplasmic component
GD442_13935	COG1172	Belongs to the binding-protein-dependent transport system permease family
GD442_13940	COG1172	Belongs to the binding-protein-dependent transport system permease family
GD442_13950	COG2390	Transcriptional regulator
GD442_13955	COG1070	Carbohydrate kinase
GD442_13975	COG2329	Antibiotic biosynthesis monooxygenase
GD442_13995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GD442_14010	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GD442_14015	COG4187	Peptidase family M20/M25/M40
GD442_14020	COG1414	Transcriptional regulator
GD442_14025	COG0833	amino acid
GD442_14035	COG3239	Fatty acid desaturase
GD442_14045	COG2720	vancomycin resistance protein
GD442_14050	COG1785	Belongs to the alkaline phosphatase family
GD442_14060	COG3655	Transcriptional regulator
GD442_14080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_14085	COG0346	lactoylglutathione lyase activity
GD442_14110	COG0714	Associated with various cellular activities
GD442_14135	COG0463	Glycosyl transferase, family 2
GD442_14165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GD442_14170	COG0753	catalase activity
GD442_14210	COG0714	Associated with various cellular activities
GD442_14275	COG0778	Nitroreductase
GD442_14280	COG1846	Transcriptional regulator
GD442_14300	COG3831	ATPase activity
GD442_14300	COG4884	unkown
GD442_14325	COG0037	tRNA processing
GD442_14325	COG0590	tRNA wobble adenosine to inosine editing
GD442_14330	COG0456	acetyltransferase
GD442_14345	COG0697	spore germination
GD442_14350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_14405	COG0730	response to heat
GD442_14415	COG0833	amino acid
GD442_14425	COG4335	DNA alkylation repair
GD442_14495	COG1984	allophanate hydrolase subunit 2
GD442_14500	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GD442_14505	COG1414	Transcriptional regulator
GD442_14520	COG0640	Transcriptional regulator
GD442_14530	COG1960	acyl-CoA dehydrogenase activity
GD442_14565	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GD442_14590	COG3848	Pyruvate phosphate dikinase
GD442_14590	COG0574	Belongs to the PEP-utilizing enzyme family
GD442_14595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_14615	COG1063	alcohol dehydrogenase
GD442_14620	COG1027	Aspartate ammonia-lyase
GD442_14625	COG0252	asparaginase activity
GD442_14630	COG1396	sequence-specific DNA binding
GD442_14665	COG5002	protein histidine kinase activity
GD442_14690	COG2207	Transcriptional regulator
GD442_14705	COG0322	excinuclease ABC activity
GD442_14710	COG0531	amino acid
GD442_14715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GD442_14725	COG0531	amino acid
GD442_14730	COG0697	spore germination
GD442_14735	COG0784	Response regulator, receiver
GD442_14740	COG4191	Histidine kinase
GD442_14750	COG1115	amino acid carrier protein
GD442_14760	COG2124	cytochrome p450
GD442_14775	COG0737	Belongs to the 5'-nucleotidase family
GD442_14780	COG2267	carboxylic ester hydrolase activity
GD442_14785	COG1335	isochorismatase
GD442_14805	COG0583	DNA-binding transcription factor activity
GD442_14810	COG1846	Transcriptional regulator
GD442_14815	COG0598	Magnesium transport protein CorA
GD442_14835	COG1073	alpha beta
GD442_14855	COG0415	Belongs to the DNA photolyase family
GD442_14870	COG0288	reversible hydration of carbon dioxide
GD442_14880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GD442_14885	COG5609	conserved protein (DUF2294)
GD442_14900	COG0697	spore germination
GD442_14905	COG0726	polysaccharide deacetylase
GD442_14915	COG1575	Belongs to the MenA family. Type 1 subfamily
GD442_14925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_14935	COG0798	PFAM Bile acid sodium symporter
GD442_14940	COG0346	lactoylglutathione lyase activity
GD442_14945	COG0640	Transcriptional regulator
GD442_14955	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GD442_14960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GD442_14960	COG3320	Male sterility
GD442_14970	COG2814	Major facilitator Superfamily
GD442_14975	COG1309	transcriptional regulator
GD442_14980	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_14985	COG1522	sequence-specific DNA binding
GD442_15000	COG0346	lactoylglutathione lyase activity
GD442_15075	COG0745	RESPONSE REGULATOR receiver
GD442_15080	COG3850	Histidine kinase
GD442_15080	COG5002	protein histidine kinase activity
GD442_15120	COG1136	(ABC) transporter
GD442_15155	COG2814	Major facilitator Superfamily
GD442_15170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GD442_15185	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GD442_15200	COG0577	efflux transmembrane transporter activity
GD442_15220	COG3850	Histidine kinase
GD442_15220	COG5002	protein histidine kinase activity
GD442_15230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_15240	COG1619	proteins homologs of microcin C7 resistance protein MccF
GD442_15285	COG0814	amino acid
GD442_15290	COG1760	l-serine dehydratase
GD442_15295	COG1760	l-serine dehydratase
GD442_15305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GD442_15310	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
GD442_15320	COG1335	isochorismatase
GD442_15325	COG1522	sequence-specific DNA binding
GD442_15330	COG0531	amino acid
GD442_15345	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GD442_15365	COG0662	Cupin 2, conserved barrel domain protein
GD442_15370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_15370	COG2207	Transcriptional regulator
GD442_15390	COG5632	N-Acetylmuramoyl-L-alanine amidase
GD442_15390	COG3409	Peptidoglycan-binding domain 1 protein
GD442_15475	COG5444	nuclease activity
GD442_15500	COG1876	peptidase activity
GD442_15505	COG2843	Capsule synthesis protein
GD442_15515	COG0477	Major facilitator Superfamily
GD442_15530	COG1846	Transcriptional regulator
GD442_15535	COG2814	Major facilitator Superfamily
GD442_15545	COG2031	fatty acid transporter
GD442_15555	COG2249	NAD(P)H dehydrogenase (quinone) activity
GD442_15610	COG1288	antiporter activity
GD442_15615	COG2356	endonuclease I
GD442_15630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GD442_15650	COG1733	regulation of RNA biosynthetic process
GD442_15655	COG0778	Nitroreductase
GD442_15685	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_15695	COG1131	(ABC) transporter
GD442_15720	COG1011	Hydrolase
GD442_15750	COG0180	Tryptophanyl-tRNA synthetase
GD442_15760	COG0628	permease
GD442_15785	COG0500	methyltransferase
GD442_15795	COG0477	Major facilitator Superfamily
GD442_15825	COG1253	flavin adenine dinucleotide binding
GD442_15830	COG0789	Transcriptional regulator
GD442_15840	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GD442_15870	COG0697	spore germination
GD442_15880	COG1357	PFAM Pentapeptide repeats (8 copies)
GD442_15885	COG3813	Protein conserved in bacteria
GD442_15890	COG2706	6-phosphogluconolactonase activity
GD442_15895	COG1070	Carbohydrate kinase
GD442_15910	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GD442_15915	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GD442_15920	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GD442_15930	COG0604	alcohol dehydrogenase
GD442_15935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GD442_15945	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_15960	COG0840	transmembrane signaling receptor activity
GD442_15970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GD442_15970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GD442_15975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GD442_15975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GD442_15980	COG1733	regulation of RNA biosynthetic process
GD442_15995	COG0656	L-ascorbic acid biosynthetic process
GD442_16000	COG2814	Major facilitator Superfamily
GD442_16025	COG2824	Alkylphosphonate utilization operon protein PhnA
GD442_16030	COG0659	secondary active sulfate transmembrane transporter activity
GD442_16045	COG0814	amino acid
GD442_16075	COG1733	regulation of RNA biosynthetic process
GD442_16080	COG2188	Transcriptional regulator
GD442_16085	COG0673	inositol 2-dehydrogenase activity
GD442_16090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GD442_16095	COG1733	regulation of RNA biosynthetic process
GD442_16100	COG1733	regulation of RNA biosynthetic process
GD442_16125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_16145	COG0384	phenazine biosynthesis protein PhzF
GD442_16165	COG0318	PFAM AMP-dependent synthetase and ligase
GD442_16170	COG2249	NAD(P)H dehydrogenase (quinone) activity
GD442_16175	COG1733	regulation of RNA biosynthetic process
GD442_16185	COG0726	polysaccharide deacetylase
GD442_16195	COG1191	sigma factor activity
GD442_16205	COG1280	lysine exporter protein (LysE YggA)
GD442_16240	COG3152	Membrane
GD442_16265	COG1151	hydroxylamine reductase activity
GD442_16275	COG3409	Peptidoglycan-binding domain 1 protein
GD442_16275	COG3757	hydrolase, family 25
GD442_16310	COG2072	flavoprotein involved in K transport
GD442_16345	COG1113	amino acid transport
GD442_16350	COG2814	Major facilitator Superfamily
GD442_16380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GD442_16385	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GD442_16400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_16405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_16410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_16415	COG3739	integral membrane protein
GD442_16435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_16450	COG0583	DNA-binding transcription factor activity
GD442_16485	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GD442_16490	COG1164	Oligoendopeptidase f
GD442_16510	COG3781	membrane
GD442_16525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GD442_16550	COG0584	glycerophosphoryl diester phosphodiesterase
GD442_16560	COG0640	Transcriptional regulator
GD442_16565	COG0604	alcohol dehydrogenase
GD442_16575	COG0457	Tetratricopeptide repeat
GD442_16590	COG0277	FAD linked oxidase domain protein
GD442_16615	COG1183	phosphatidylcholine synthase activity
GD442_16620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GD442_16620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_16625	COG1252	NADH dehydrogenase
GD442_16635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GD442_16645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GD442_16655	COG0457	Tetratricopeptide repeat
GD442_16725	COG3852	Histidine kinase
GD442_16735	COG1285	pathogenesis
GD442_16745	COG2514	catechol 2,3-dioxygenase activity
GD442_16750	COG2720	vancomycin resistance protein
GD442_16775	COG1278	Cold shock
GD442_16785	COG0716	FMN binding
GD442_16815	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_16825	COG0165	Argininosuccinate lyase
GD442_16840	COG4145	pantothenate transmembrane transporter activity
GD442_16850	COG1012	belongs to the aldehyde dehydrogenase family
GD442_16855	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_16865	COG1657	PFAM Prenyltransferase squalene oxidase
GD442_16870	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GD442_16875	COG2962	Rard protein
GD442_16880	COG3326	Membrane
GD442_16895	COG0489	protein tyrosine kinase activity
GD442_16905	COG0314	molybdopterin synthase activity
GD442_16910	COG0303	'Molybdopterin
GD442_16915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GD442_16920	COG2116	formate transmembrane transporter activity
GD442_16930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GD442_16935	COG5609	conserved protein (DUF2294)
GD442_16940	COG2427	Protein of unknown function (DUF1641)
GD442_16945	COG3383	formate dehydrogenase (NAD+) activity
GD442_16950	COG0697	spore germination
GD442_16965	COG0531	amino acid
GD442_17000	COG2226	methyltransferase
GD442_17005	COG4166	transmembrane transport
GD442_17010	COG4166	transmembrane transport
GD442_17015	COG4166	transmembrane transport
GD442_17020	COG1301	dicarboxylic acid transport
GD442_17025	COG1316	TRANSCRIPTIONal
GD442_17035	COG1595	DNA-templated transcription, initiation
GD442_17045	COG1131	(ABC) transporter
GD442_17065	COG0673	inositol 2-dehydrogenase activity
GD442_17070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GD442_17075	COG0187	DNA topoisomerase II activity
GD442_17080	COG1832	CoA-binding protein
GD442_17085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GD442_17090	COG0745	RESPONSE REGULATOR receiver
GD442_17110	COG4841	protein insertion into membrane
GD442_17115	COG0824	Thioesterase
GD442_17145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD442_17155	COG2274	protein secretion by the type I secretion system
GD442_17160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GD442_17170	COG0726	polysaccharide deacetylase
GD442_17190	COG2211	Major facilitator Superfamily
GD442_17200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GD442_17215	COG0183	Belongs to the thiolase family
GD442_17220	COG0318	PFAM AMP-dependent synthetase and ligase
GD442_17225	COG1268	BioY protein
GD442_17230	COG0318	PFAM AMP-dependent synthetase and ligase
GD442_17275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_17285	COG5002	protein histidine kinase activity
GD442_17290	COG0400	carboxylic ester hydrolase activity
GD442_17295	COG0346	lactoylglutathione lyase activity
GD442_17300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GD442_17310	COG0069	glutamate synthase activity
GD442_17315	COG1902	pentaerythritol trinitrate reductase activity
GD442_17320	COG1329	Transcriptional regulator
GD442_17325	COG0010	Belongs to the arginase family
GD442_17375	COG4846	Membrane protein involved in cytochrome C biogenesis
GD442_17380	COG0785	Cytochrome C biogenesis protein
GD442_17400	COG1131	(ABC) transporter
GD442_17415	COG0583	DNA-binding transcription factor activity
GD442_17425	COG1346	cytolysis
GD442_17440	COG0730	response to heat
GD442_17465	COG1132	(ABC) transporter
GD442_17470	COG1132	(ABC) transporter
GD442_17495	COG3639	organic phosphonate transmembrane transporter activity
GD442_17505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GD442_17510	COG0737	Belongs to the 5'-nucleotidase family
GD442_17520	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GD442_17540	COG1695	Transcriptional regulator
GD442_17545	COG0174	glutamine synthetase
GD442_17550	COG0789	Transcriptional regulator
GD442_17555	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GD442_17560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GD442_17565	COG2860	membrane
GD442_17570	COG0464	growth
GD442_17600	COG3584	3D domain protein
GD442_17600	COG1388	LysM domain
GD442_17605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GD442_17605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GD442_17605	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GD442_17610	COG1105	Belongs to the carbohydrate kinase PfkB family
GD442_17615	COG1349	DNA-binding transcription factor activity
GD442_17620	COG1979	alcohol dehydrogenase
GD442_17625	COG2322	membrane
GD442_17635	COG1113	amino acid transport
GD442_17645	COG1408	metallophosphoesterase
GD442_17650	COG2116	formate transmembrane transporter activity
GD442_17665	COG2217	Heavy metal translocating P-type atpase
GD442_17670	COG2608	mercury ion transmembrane transporter activity
GD442_17675	COG1937	Protein conserved in bacteria
GD442_17685	COG2819	hydrolase of the alpha beta superfamily
GD442_17690	COG1120	ATPase activity
GD442_17695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_17700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_17705	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_17710	COG0708	Exodeoxyribonuclease III
GD442_17715	COG2169	Transcriptional regulator
GD442_17720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GD442_17725	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GD442_17745	COG2267	carboxylic ester hydrolase activity
GD442_17750	COG3300	MHYT domain
GD442_17750	COG5001	Diguanylate cyclase
GD442_17770	COG1086	Polysaccharide biosynthesis protein
GD442_17790	COG1346	cytolysis
GD442_17800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GD442_17810	COG2188	Transcriptional regulator
GD442_17815	COG2723	6-phospho-beta-galactosidase activity
GD442_17825	COG1404	Belongs to the peptidase S8 family
GD442_17830	COG3773	Cell wall hydrolase
GD442_17840	COG1368	sulfuric ester hydrolase activity
GD442_17845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GD442_17870	COG4550	Control of competence regulator ComK, YlbF/YmcA
GD442_17880	COG1013	pyruvate-flavodoxin oxidoreductase activity
GD442_17885	COG0674	pyruvate-flavodoxin oxidoreductase activity
GD442_17885	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GD442_17895	COG2359	stage V sporulation protein S
GD442_17900	COG1692	metallophosphoesterase
GD442_17920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GD442_17925	COG1426	Protein conserved in bacteria
GD442_17940	COG0300	oxidoreductase activity
GD442_17945	COG0612	Peptidase, M16
GD442_17950	COG0612	Peptidase, M16
GD442_17975	COG2188	Transcriptional regulator
GD442_17990	COG0740	serine-type endopeptidase activity
GD442_17995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GD442_18005	COG0527	aspartate kinase activity
GD442_18010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GD442_18015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GD442_18180	COG0582	viral genome integration into host DNA
GD442_18210	COG0305	Participates in initiation and elongation during chromosome replication
GD442_18250	COG1396	sequence-specific DNA binding
GD442_18280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GD442_18285	COG1873	PFAM PRC-barrel domain
GD442_18290	COG0612	Peptidase, M16
GD442_18295	COG0726	polysaccharide deacetylase
GD442_18310	COG0196	riboflavin kinase activity
GD442_18325	COG1550	Protein conserved in bacteria
GD442_18335	COG1358	cellular component organization or biogenesis
GD442_18340	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GD442_18345	COG0195	Participates in both transcription termination and antitermination
GD442_18365	COG0750	zinc metalloprotease
GD442_18375	COG4589	Belongs to the CDS family
GD442_18420	COG4974	Belongs to the 'phage' integrase family
GD442_18430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GD442_18435	COG0758	DNA mediated transformation
GD442_18440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GD442_18480	COG1837	Belongs to the UPF0109 family
GD442_18490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GD442_18500	COG0552	protein localization to endoplasmic reticulum
GD442_18505	COG1196	nuclear chromosome segregation
GD442_18520	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_18525	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GD442_18540	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GD442_18545	COG1461	Dihydroxyacetone kinase
GD442_18550	COG1302	Protein conserved in bacteria
GD442_18565	COG1564	THIamine pyrophosphokinase
GD442_18570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GD442_18580	COG0515	serine threonine protein kinase
GD442_18580	COG2815	serine threonine protein kinase
GD442_18585	COG0631	protein serine/threonine phosphatase activity
GD442_18595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GD442_18595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GD442_18610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GD442_18615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GD442_18635	COG1561	YicC-like family, N-terminal region
GD442_18640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GD442_18650	COG0006	proline dipeptidase activity
GD442_18660	COG3069	C4-dicarboxylate transmembrane transporter activity
GD442_18720	COG0564	pseudouridine synthase activity
GD442_18740	COG3599	regulation of cell shape
GD442_18745	COG2302	S4 RNA-binding domain
GD442_18750	COG0762	integral membrane protein
GD442_18760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GD442_18770	COG1873	PFAM PRC-barrel domain
GD442_18775	COG1191	sigma factor activity
GD442_18780	COG1191	sigma factor activity
GD442_18790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GD442_18795	COG0849	cell division
GD442_18815	COG0772	Belongs to the SEDS family
GD442_18835	COG0768	penicillin binding
GD442_18860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GD442_18880	COG1399	metal-binding, possibly nucleic acid-binding protein
GD442_18890	COG3480	Lon protease (S16) C-terminal proteolytic domain
GD442_18895	COG1752	Esterase of the alpha-beta hydrolase superfamily
GD442_18900	COG3314	Sporulation integral membrane protein YlbJ
GD442_18910	COG0742	ribosomal rna small subunit methyltransferase
GD442_18930	COG3679	Belongs to the UPF0342 family
GD442_18935	COG0406	alpha-ribazole phosphatase activity
GD442_18950	COG2340	Cysteine-rich secretory protein family
GD442_18965	COG3336	cytochrome c oxidase
GD442_19000	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GD442_19005	COG0772	Belongs to the SEDS family
GD442_19015	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GD442_19020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GD442_19030	COG4896	Protein conserved in bacteria
GD442_19055	COG0483	inositol monophosphate 1-phosphatase activity
GD442_19075	COG1982	Orn Lys Arg decarboxylase major
GD442_19125	COG0022	dehydrogenase e1 component
GD442_19130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GD442_19145	COG0561	phosphatase activity
GD442_19155	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GD442_19160	COG0569	domain protein
GD442_19180	COG0583	DNA-binding transcription factor activity
GD442_19185	COG0517	IMP dehydrogenase activity
GD442_19195	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GD442_19200	COG4703	Protein of unknown function (DUF1797)
GD442_19215	COG2200	EAL domain
GD442_19220	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_19225	COG1408	metallophosphoesterase
GD442_19275	COG2814	Major facilitator Superfamily
GD442_19295	COG3209	COG3209 Rhs family protein
GD442_19305	COG2205	protein histidine kinase activity
GD442_19315	COG0436	Aminotransferase
GD442_19320	COG1609	Transcriptional regulator
GD442_19325	COG3833	ABC-type maltose transport systems, permease component
GD442_19330	COG1175	transmembrane transport
GD442_19335	COG2182	Extracellular solute-binding protein
GD442_19345	COG0366	Alpha amylase catalytic
GD442_19350	COG3842	ATPase activity
GD442_19390	COG0183	Belongs to the thiolase family
GD442_19425	COG1695	Transcriptional regulator
GD442_19430	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_19450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GD442_19455	COG0436	Aminotransferase
GD442_19490	COG2084	Dehydrogenase
GD442_19500	COG2203	Gaf domain
GD442_19500	COG2199	diguanylate cyclase activity
GD442_19505	COG0778	Nitroreductase
GD442_19530	COG2190	(PTS) system
GD442_19530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GD442_19530	COG1263	PTS System
GD442_19535	COG3711	transcriptional antiterminator
GD442_19555	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GD442_19580	COG1547	Domain of unknown function (DUF309)
GD442_19585	COG0456	acetyltransferase
GD442_19590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GD442_19595	COG4086	secreted protein
GD442_19600	COG0561	phosphatase activity
GD442_19605	COG0697	spore germination
GD442_19620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GD442_19645	COG0733	neurotransmitter:sodium symporter activity
GD442_19665	COG1686	Belongs to the peptidase S11 family
GD442_19670	COG1725	Transcriptional regulator
GD442_19675	COG1131	(ABC) transporter
GD442_19695	COG1846	Transcriptional regulator
GD442_19710	COG0598	Magnesium transport protein CorA
GD442_19735	COG4974	Belongs to the 'phage' integrase family
GD442_19745	COG0735	belongs to the Fur family
GD442_19750	COG1300	Membrane
GD442_19770	COG0667	Aldo Keto reductase
GD442_19775	COG0656	L-ascorbic acid biosynthetic process
GD442_19780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GD442_19780	COG0456	acetyltransferase
GD442_19790	COG1525	nuclease
GD442_19790	COG4085	toxin activity
GD442_19790	COG0737	Belongs to the 5'-nucleotidase family
GD442_19800	COG0596	Alpha beta hydrolase
GD442_19805	COG2056	Na+-H+ antiporter family
GD442_19810	COG1609	Transcriptional regulator
GD442_19815	COG0456	acetyltransferase
GD442_19820	COG1073	alpha beta
GD442_19835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GD442_19835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GD442_19840	COG0307	riboflavin synthase, alpha
GD442_19870	COG1073	alpha beta
GD442_19870	COG2226	methyltransferase
GD442_19885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GD442_19900	COG0737	Belongs to the 5'-nucleotidase family
GD442_19910	COG1522	sequence-specific DNA binding
GD442_19955	COG0300	oxidoreductase activity
GD442_19960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_19965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GD442_19970	COG1760	l-serine dehydratase
GD442_19975	COG1760	l-serine dehydratase
GD442_20005	COG1285	pathogenesis
GD442_20015	COG2195	Cleaves the N-terminal amino acid of tripeptides
GD442_20020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_20035	COG1376	ErfK ybiS ycfS ynhG family protein
GD442_20040	COG4129	membrane
GD442_20045	COG1126	abc transporter atp-binding protein
GD442_20050	COG0765	amino acid transport
GD442_20055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GD442_20075	COG2323	membrane
GD442_20080	COG0772	Belongs to the SEDS family
GD442_20085	COG0508	dehydrogenase complex catalyzes the overall conversion of
GD442_20090	COG0022	dehydrogenase e1 component
GD442_20095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GD442_20100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GD442_20110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GD442_20115	COG0280	phosphate acetyltransferase
GD442_20120	COG3290	protein histidine kinase activity
GD442_20120	COG3829	transcription factor binding
GD442_20130	COG0584	glycerophosphoryl diester phosphodiesterase
GD442_20135	COG3093	addiction module antidote protein HigA
GD442_20150	COG0750	zinc metalloprotease
GD442_20155	COG0497	DNA recombination
GD442_20165	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GD442_20175	COG0142	geranyltranstransferase activity
GD442_20200	COG1302	Protein conserved in bacteria
GD442_20205	COG0439	Biotin carboxylase
GD442_20210	COG0511	ligase activity, forming carbon-carbon bonds
GD442_20255	COG3854	ATPases associated with a variety of cellular activities
GD442_20280	COG0006	proline dipeptidase activity
GD442_20295	COG3872	metal-dependent enzyme
GD442_20305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GD442_20340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GD442_20350	COG1609	Transcriptional regulator
GD442_20360	COG2076	Multidrug Resistance protein
GD442_20365	COG2076	Multidrug Resistance protein
GD442_20395	COG1131	(ABC) transporter
GD442_20400	COG1725	Transcriptional regulator
GD442_20430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GD442_20510	COG5632	N-Acetylmuramoyl-L-alanine amidase
GD442_20510	COG3409	Peptidoglycan-binding domain 1 protein
GD442_20510	COG1388	LysM domain
GD442_20515	COG4824	toxin secretion phage lysis holin
GD442_20640	COG0582	viral genome integration into host DNA
GD442_20670	COG0270	DNA (cytosine-5-)-methyltransferase activity
GD442_20720	COG2002	toxin-antitoxin pair type II binding
GD442_20805	COG1459	type II secretion system
GD442_20810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GD442_20865	COG1410	methionine synthase
GD442_20865	COG0646	methionine synthase
GD442_20870	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GD442_20870	COG0646	methionine synthase
GD442_20875	COG0626	cystathionine gamma-synthase activity
GD442_20880	COG0626	cystathionine gamma-synthase activity
GD442_20900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_20910	COG1940	carbohydrate kinase activity
GD442_20915	COG4483	Protein conserved in bacteria
GD442_20920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GD442_20930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GD442_20940	COG0704	Plays a role in the regulation of phosphate uptake
GD442_20950	COG0573	inorganic phosphate transmembrane transporter activity
GD442_20955	COG0573	inorganic phosphate transmembrane transporter activity
GD442_20960	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GD442_20970	COG0477	Major facilitator Superfamily
GD442_20975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GD442_20985	COG5521	maltodextrose utilization protein MalA
GD442_21000	COG0735	belongs to the Fur family
GD442_21005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GD442_21010	COG1121	(ABC) transporter
GD442_21015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_21045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GD442_21050	COG2384	SAM-dependent methyltransferase
GD442_21060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GD442_21065	COG0358	DNA primase activity
GD442_21075	COG0517	IMP dehydrogenase activity
GD442_21090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GD442_21095	COG0295	cytidine deaminase activity
GD442_21100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GD442_21110	COG1480	7TM receptor with intracellular HD hydrolase
GD442_21115	COG1702	phosphate starvation-inducible protein PhoH
GD442_21130	COG1610	YqeY-like protein
GD442_21140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GD442_21145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GD442_21175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GD442_21180	COG1733	regulation of RNA biosynthetic process
GD442_21205	COG1466	dna polymerase III delta subunit
GD442_21215	COG2333	competence protein COMEC
GD442_21215	COG0658	competence protein
GD442_21220	COG2131	deaminase
GD442_21225	COG1596	polysaccharide export
GD442_21225	COG1555	photosystem II stabilization
GD442_21230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GD442_21235	COG2226	methyltransferase
GD442_21240	COG0799	negative regulation of ribosome biogenesis
GD442_21245	COG1713	HD superfamily hydrolase involved in NAD metabolism
GD442_21255	COG1534	Rna-binding protein
GD442_21265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GD442_21270	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GD442_21285	COG1191	sigma factor activity
GD442_21305	COG0778	Nitroreductase
GD442_21310	COG2357	RelA SpoT domain protein
GD442_21320	COG1785	Belongs to the alkaline phosphatase family
GD442_21330	COG2267	carboxylic ester hydrolase activity
GD442_21370	COG1404	Belongs to the peptidase S8 family
GD442_21375	COG3186	Phenylalanine-4-hydroxylase
GD442_21385	COG2514	catechol 2,3-dioxygenase activity
GD442_21390	COG2259	Doxx family
GD442_21430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_21440	COG1012	belongs to the aldehyde dehydrogenase family
GD442_21440	COG1454	alcohol dehydrogenase
GD442_21445	COG0626	cystathionine gamma-synthase activity
GD442_21450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GD442_21475	COG0768	penicillin binding
GD442_21510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GD442_21540	COG0628	permease
GD442_21560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GD442_21575	COG1104	cysteine desulfurase activity
GD442_21580	COG1959	2 iron, 2 sulfur cluster binding
GD442_21585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GD442_21595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GD442_21615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GD442_21625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GD442_21625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GD442_21630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GD442_21635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GD442_21635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GD442_21645	COG2244	polysaccharide biosynthetic process
GD442_21650	COG2323	membrane
GD442_21660	COG1862	Preprotein translocase
GD442_21690	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GD442_21720	COG0157	Belongs to the NadC ModD family
GD442_21725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GD442_21730	COG1104	cysteine desulfurase activity
GD442_21735	COG1827	regulation of RNA biosynthetic process
GD442_21740	COG2258	MOSC domain
GD442_21745	COG0077	Prephenate dehydratase
GD442_21750	COG0577	efflux transmembrane transporter activity
GD442_21755	COG0577	efflux transmembrane transporter activity
GD442_21760	COG1136	(ABC) transporter
GD442_21765	COG5002	protein histidine kinase activity
GD442_21770	COG0745	RESPONSE REGULATOR receiver
GD442_21780	COG3290	protein histidine kinase activity
GD442_21795	COG1530	ribonuclease E activity
GD442_21800	COG1994	Peptidase M50
GD442_21805	COG0739	heme binding
GD442_21810	COG2894	cell division
GD442_21825	COG1792	Involved in formation and maintenance of cell shape
GD442_21830	COG1077	Cell shape determining protein MreB Mrl
GD442_21850	COG0285	dihydrofolate synthase activity
GD442_21865	COG1388	LysM domain
GD442_21875	COG0113	porphobilinogen synthase activity
GD442_21880	COG1587	Uroporphyrinogen-III synthase
GD442_21890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GD442_21900	COG1846	Transcriptional regulator
GD442_21905	COG1764	response to oxidative stress
GD442_21920	COG0470	DNA polymerase III
GD442_21920	COG1067	ATP-dependent peptidase activity
GD442_21965	COG0622	Phosphoesterase
GD442_21980	COG5401	PFAM Sporulation and spore germination
GD442_22000	COG1309	transcriptional regulator
GD442_22010	COG2197	response regulator
GD442_22085	COG2197	response regulator
GD442_22090	COG2233	PERMEase
GD442_22095	COG0402	S-adenosylhomocysteine deaminase activity
GD442_22100	COG1983	PspC domain protein
GD442_22105	COG1396	sequence-specific DNA binding
GD442_22110	COG0697	spore germination
GD442_22120	COG1959	2 iron, 2 sulfur cluster binding
GD442_22125	COG1668	transmembrane transport
GD442_22130	COG4152	abc transporter atp-binding protein
GD442_22135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
GD442_22140	COG1360	Flagellar Motor Protein
GD442_22145	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GD442_22150	COG1876	peptidase activity
GD442_22155	COG0824	Thioesterase
GD442_22160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GD442_22165	COG1053	succinate dehydrogenase
GD442_22170	COG2009	succinate dehydrogenase
GD442_22175	COG1719	4-vinyl reductase, 4VR
GD442_22185	COG3118	belongs to the thioredoxin family
GD442_22190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GD442_22195	COG2086	electron transfer activity
GD442_22200	COG1024	Enoyl-CoA hydratase
GD442_22205	COG1309	transcriptional regulator
GD442_22210	COG0318	PFAM AMP-dependent synthetase and ligase
GD442_22235	COG2318	DinB family
GD442_22260	COG1131	(ABC) transporter
GD442_22265	COG2205	protein histidine kinase activity
GD442_22270	COG0745	RESPONSE REGULATOR receiver
GD442_22275	COG4895	conserved protein (DUF2196)
GD442_22280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GD442_22290	COG4509	Sortase family
GD442_22295	COG1120	ATPase activity
GD442_22310	COG5386	Cell surface protein
GD442_22320	COG5386	Cell surface protein
GD442_22325	COG1114	Component of the transport system for branched-chain amino acids
GD442_22330	COG1187	pseudouridine synthase activity
GD442_22340	COG1796	DNA polymerase
GD442_22340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GD442_22345	COG1286	toxin biosynthetic process
GD442_22390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GD442_22400	COG1418	mRNA catabolic process
GD442_22420	COG2814	Major facilitator Superfamily
GD442_22425	COG1566	PFAM secretion protein HlyD family protein
GD442_22430	COG1309	transcriptional regulator
GD442_22435	COG1363	Peptidase, m42
GD442_22460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GD442_22475	COG1484	DNA-dependent DNA replication
GD442_22480	COG3611	Membrane attachment protein
GD442_22490	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GD442_22495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GD442_22505	COG1971	Probably functions as a manganese efflux pump
GD442_22515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GD442_22515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GD442_22520	COG5002	protein histidine kinase activity
GD442_22525	COG0745	RESPONSE REGULATOR receiver
GD442_22540	COG0538	isocitrate dehydrogenase activity
GD442_22545	COG0372	Belongs to the citrate synthase family
GD442_22555	COG0628	permease
GD442_22560	COG3030	protein affecting phage T7 exclusion by the F plasmid
GD442_22585	COG1725	Transcriptional regulator
GD442_22590	COG0281	malic enzyme
GD442_22595	COG0587	DNA-directed DNA polymerase activity
GD442_22610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GD442_22625	COG4109	DRTGG domain
GD442_22635	COG0006	proline dipeptidase activity
GD442_22675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_22680	COG0662	Cupin 2, conserved barrel domain protein
GD442_22695	COG1028	Short-chain dehydrogenase reductase Sdr
GD442_22700	COG0589	response to stress
GD442_22705	COG0346	lactoylglutathione lyase activity
GD442_22745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_22770	COG0827	DNA restriction-modification system
GD442_22775	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GD442_22780	COG3874	Sporulation protein YtfJ
GD442_22795	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GD442_22805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GD442_22820	COG1104	cysteine desulfurase activity
GD442_22830	COG0583	DNA-binding transcription factor activity
GD442_22835	COG0697	spore germination
GD442_22840	COG1309	transcriptional regulator
GD442_22845	COG1956	GAF domain-containing protein
GD442_22850	COG0626	cystathionine gamma-synthase activity
GD442_22875	COG0110	maltose O-acetyltransferase activity
GD442_22880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GD442_22885	COG0454	-acetyltransferase
GD442_22890	COG0517	IMP dehydrogenase activity
GD442_22895	COG0123	including yeast histone deacetylase and acetoin utilization protein
GD442_22910	COG0745	RESPONSE REGULATOR receiver
GD442_22920	COG0666	response to abiotic stimulus
GD442_22955	COG1609	Transcriptional regulator
GD442_22960	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GD442_22960	COG1605	Chorismate mutase
GD442_22965	COG4851	CamS sex pheromone cAM373 precursor
GD442_22970	COG3118	belongs to the thioredoxin family
GD442_22980	COG2309	aminopeptidase activity
GD442_23005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_23020	COG1674	ftsk spoiiie
GD442_23025	COG1388	LysM domain
GD442_23025	COG0860	N-Acetylmuramoyl-L-alanine amidase
GD442_23035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GD442_23045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD442_23050	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GD442_23055	COG1363	Peptidase, m42
GD442_23065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_23080	COG0510	thiamine kinase activity
GD442_23085	COG1523	belongs to the glycosyl hydrolase 13 family
GD442_23095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GD442_23100	COG1349	DNA-binding transcription factor activity
GD442_23105	COG1187	pseudouridine synthase activity
GD442_23110	COG2244	polysaccharide biosynthetic process
GD442_23115	COG2081	HI0933 family
GD442_23120	COG2814	Major facilitator Superfamily
GD442_23130	COG3832	glyoxalase III activity
GD442_23150	COG1329	Transcriptional regulator
GD442_23175	COG0314	molybdopterin synthase activity
GD442_23180	COG1763	Mo-molybdopterin cofactor biosynthetic process
GD442_23185	COG0303	'Molybdopterin
GD442_23195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GD442_23200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GD442_23220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GD442_23230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GD442_23270	COG2814	Major facilitator Superfamily
GD442_23275	COG0475	glutathione-regulated potassium exporter activity
GD442_23280	COG0490	domain, Protein
GD442_23285	COG0582	viral genome integration into host DNA
GD442_23295	COG1136	(ABC) transporter
GD442_23315	COG1242	4 iron, 4 sulfur cluster binding
GD442_23320	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GD442_23325	COG1794	racemase activity, acting on amino acids and derivatives
GD442_23345	COG2267	carboxylic ester hydrolase activity
GD442_23350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GD442_23355	COG0671	phosphoesterase, PA-phosphatase related
GD442_23360	COG0438	transferase activity, transferring glycosyl groups
GD442_23380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_23430	COG5002	protein histidine kinase activity
GD442_23435	COG3852	Histidine kinase
GD442_23450	COG2267	carboxylic ester hydrolase activity
GD442_23455	COG1368	sulfuric ester hydrolase activity
GD442_23475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GD442_23480	COG1116	anion transmembrane transporter activity
GD442_23485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GD442_23510	COG0494	nUDIX hydrolase
GD442_23550	COG0288	reversible hydration of carbon dioxide
GD442_23555	COG1271	oxidase subunit
GD442_23560	COG1294	oxidase, subunit
GD442_23575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_23595	COG1842	Phage shock protein A
GD442_23625	COG5002	protein histidine kinase activity
GD442_23630	COG0745	RESPONSE REGULATOR receiver
GD442_23660	COG1597	lipid kinase activity
GD442_23680	COG0577	efflux transmembrane transporter activity
GD442_23685	COG1136	(ABC) transporter
GD442_23700	COG0586	Pfam SNARE associated Golgi protein
GD442_23705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GD442_23710	COG0577	efflux transmembrane transporter activity
GD442_23715	COG1136	(ABC) transporter
GD442_23720	COG2207	Transcriptional regulator
GD442_23720	COG3708	Transcriptional regulator
GD442_23730	COG5658	integral membrane protein
GD442_23735	COG0640	Transcriptional regulator
GD442_23740	COG0745	RESPONSE REGULATOR receiver
GD442_23745	COG2205	protein histidine kinase activity
GD442_23750	COG0577	efflux transmembrane transporter activity
GD442_23755	COG0577	efflux transmembrane transporter activity
GD442_23760	COG1136	(ABC) transporter
GD442_23765	COG0577	efflux transmembrane transporter activity
GD442_23810	COG3964	amidohydrolase
GD442_23830	COG4948	Mandelate Racemase Muconate Lactonizing
GD442_23840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GD442_23845	COG0596	Alpha beta hydrolase
GD442_23855	COG1169	isochorismate synthase
GD442_23860	COG1575	Belongs to the MenA family. Type 1 subfamily
GD442_23865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GD442_23870	COG1278	Cold shock
GD442_23885	COG0058	SHG alpha-glucan phosphorylase activity
GD442_23895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GD442_23915	COG1404	Belongs to the peptidase S8 family
GD442_23920	COG0039	L-malate dehydrogenase activity
GD442_24015	COG0544	peptidyl-prolyl cis-trans isomerase activity
GD442_24050	COG1285	pathogenesis
GD442_24055	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GD442_24070	COG2155	Conserved Protein
GD442_24075	COG1098	S1 RNA binding domain
GD442_24080	COG0436	Aminotransferase
GD442_24085	COG1522	sequence-specific DNA binding
GD442_24090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GD442_24095	COG2267	carboxylic ester hydrolase activity
GD442_24105	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GD442_24120	COG5018	Exonuclease
GD442_24125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GD442_24140	COG0423	glycine-tRNA ligase activity
GD442_24145	COG2050	protein possibly involved in aromatic compounds catabolism
GD442_24155	COG1268	BioY protein
GD442_24160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GD442_24165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GD442_24180	COG3584	3D domain protein
GD442_24195	COG1252	NADH dehydrogenase
GD442_24210	COG3708	Transcriptional regulator
GD442_24225	COG1683	Conserved Protein
GD442_24245	COG0316	Belongs to the HesB IscA family
GD442_24260	COG1252	NADH dehydrogenase
GD442_24275	COG0390	transport system, permease component
GD442_24280	COG2824	Alkylphosphonate utilization operon protein PhnA
GD442_24305	COG4837	Protein of unknown function (DUF1462)
GD442_24310	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GD442_24320	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GD442_24325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GD442_24345	COG1358	cellular component organization or biogenesis
GD442_24355	COG2249	NAD(P)H dehydrogenase (quinone) activity
GD442_24360	COG0647	UMP catabolic process
GD442_24370	COG2445	Protein of unknown function DUF86
GD442_24375	COG1494	fructose-1,6-bisphosphatase
GD442_24390	COG4470	Protein conserved in bacteria
GD442_24400	COG0789	Transcriptional regulator
GD442_24405	COG4377	Putative membrane peptidase family (DUF2324)
GD442_24430	COG0739	heme binding
GD442_24440	COG3377	Domain of unknown function (DUF1805)
GD442_24445	COG0737	Belongs to the 5'-nucleotidase family
GD442_24450	COG0719	Fe-S assembly protein
GD442_24455	COG0822	iron-sulfur transferase activity
GD442_24460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GD442_24465	COG0719	Fe-S assembly protein
GD442_24470	COG0396	ATPase activity
GD442_24475	COG1464	Belongs to the NlpA lipoprotein family
GD442_24480	COG1464	Belongs to the NlpA lipoprotein family
GD442_24485	COG2011	ABC-type metal ion transport system permease component
GD442_24490	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GD442_24500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GD442_24505	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GD442_24515	COG1393	Belongs to the ArsC family
GD442_24555	COG1309	transcriptional regulator
GD442_24560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GD442_24565	COG1960	acyl-CoA dehydrogenase activity
GD442_24570	COG0183	Belongs to the thiolase family
GD442_24575	COG1250	3-hydroxyacyl-CoA dehydrogenase
GD442_24575	COG1024	Enoyl-CoA hydratase
GD442_24585	COG1686	Belongs to the peptidase S11 family
GD442_24600	COG0011	TIGRFAM Protein of
GD442_24605	COG0840	transmembrane signaling receptor activity
GD442_24625	COG2814	Major facilitator Superfamily
GD442_24630	COG0531	amino acid
GD442_24655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GD442_24690	COG0586	Pfam SNARE associated Golgi protein
GD442_24700	COG1376	ErfK ybiS ycfS ynhG family protein
GD442_24705	COG0745	RESPONSE REGULATOR receiver
GD442_24710	COG5002	protein histidine kinase activity
GD442_24740	COG0840	transmembrane signaling receptor activity
GD442_24745	COG2151	metal-sulfur cluster biosynthetic enzyme
GD442_24750	COG3227	Zinc metalloprotease (Elastase)
GD442_24755	COG1741	Belongs to the pirin family
GD442_24770	COG0586	Pfam SNARE associated Golgi protein
GD442_24775	COG0475	glutathione-regulated potassium exporter activity
GD442_24780	COG0490	domain, Protein
GD442_24785	COG1115	amino acid carrier protein
GD442_24790	COG0783	Belongs to the Dps family
GD442_24805	COG1611	Belongs to the LOG family
GD442_24815	COG1528	Iron-storage protein
GD442_24825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GD442_24830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GD442_24835	COG1115	amino acid carrier protein
GD442_24840	COG1115	amino acid carrier protein
GD442_24845	COG2910	NAD(P)H-binding
GD442_24860	COG0656	L-ascorbic acid biosynthetic process
GD442_24865	COG2814	Major facilitator Superfamily
GD442_24870	COG1733	regulation of RNA biosynthetic process
GD442_24880	COG1252	NADH dehydrogenase
GD442_24885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GD442_24935	COG0488	(ABC) transporter
GD442_24940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GD442_24945	COG3223	Belongs to the PsiE family
GD442_25015	COG1309	transcriptional regulator
GD442_25030	COG0557	exoribonuclease II activity
GD442_25035	COG1647	Serine aminopeptidase, S33
GD442_25040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GD442_25045	COG1346	cytolysis
GD442_25080	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GD442_25095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GD442_25120	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GD442_25135	COG2323	membrane
GD442_25145	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GD442_25155	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GD442_25165	COG1051	belongs to the nudix hydrolase family
GD442_25175	COG0492	ferredoxin-NADP+ reductase activity
GD442_25180	COG0457	Tetratricopeptide repeat
GD442_25185	COG0110	maltose O-acetyltransferase activity
GD442_25205	COG1950	PFAM Membrane protein of
GD442_25210	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GD442_25215	COG0556	nucleotide-excision repair
GD442_25230	COG0789	Transcriptional regulator
GD442_25250	COG0583	DNA-binding transcription factor activity
GD442_25260	COG0655	NAD(P)H dehydrogenase (quinone) activity
GD442_25265	COG0488	(ABC) transporter
GD442_25275	COG1132	(ABC) transporter
GD442_25285	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GD442_25290	COG0583	DNA-binding transcription factor activity
GD442_25295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GD442_25300	COG3409	Peptidoglycan-binding domain 1 protein
GD442_25300	COG0793	Belongs to the peptidase S41A family
GD442_25305	COG2177	Part of the ABC transporter FtsEX involved in
GD442_25310	COG2884	Cell division ATP-binding protein ftsE
GD442_25335	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GD442_25340	COG1278	Cold shock
GD442_25345	COG1040	competence protein
GD442_25350	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GD442_25355	COG0791	NLP P60 protein
GD442_25360	COG1733	regulation of RNA biosynthetic process
GD442_25365	COG1307	EDD domain protein, DegV family
GD442_25370	COG1739	Uncharacterized protein family UPF0029
GD442_25375	COG1316	TRANSCRIPTIONal
GD442_25380	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GD442_25385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GD442_25390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GD442_25400	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GD442_25400	COG3933	PFAM sigma-54 factor interaction domain-containing protein
GD442_25420	COG1486	melibiose metabolic process
GD442_25425	COG1447	Phosphotransferase system cellobiose-specific component IIA
GD442_25430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GD442_25450	COG1447	Phosphotransferase system cellobiose-specific component IIA
GD442_25460	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GD442_25465	COG1301	dicarboxylic acid transport
GD442_25480	COG1511	domain protein
GD442_25485	COG0583	DNA-binding transcription factor activity
GD442_25490	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GD442_25495	COG1271	oxidase subunit
GD442_25500	COG1294	oxidase, subunit
GD442_25505	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GD442_25515	COG1620	l-lactate permease
GD442_25525	COG2389	metal-binding protein
GD442_25535	COG1368	sulfuric ester hydrolase activity
GD442_25545	COG1388	LysM domain
GD442_25545	COG0791	NLP P60 protein
GD442_25550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GD442_25560	COG1215	transferase activity, transferring glycosyl groups
GD442_25565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GD442_25570	COG3584	3D domain protein
GD442_25570	COG1388	LysM domain
GD442_25595	COG4715	Zinc finger, swim domain protein
GD442_25600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GD442_25630	COG1191	sigma factor activity
GD442_25640	COG0577	efflux transmembrane transporter activity
GD442_25645	COG1136	(ABC) transporter
GD442_25655	COG2271	Major facilitator Superfamily
GD442_25670	COG5002	protein histidine kinase activity
GD442_25675	COG0745	RESPONSE REGULATOR receiver
GD442_25680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GD442_25695	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GD442_25705	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GD442_25710	COG5434	Belongs to the glycosyl hydrolase 28 family
GD442_25715	COG0728	peptidoglycan biosynthetic process
GD442_25735	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GD442_25740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GD442_25745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GD442_25750	COG4464	protein tyrosine phosphatase activity
GD442_25755	COG0489	protein tyrosine kinase activity
GD442_25760	COG3944	biosynthesis protein
GD442_25765	COG0489	protein tyrosine kinase activity
GD442_25780	COG1609	Transcriptional regulator
GD442_25790	COG0739	heme binding
GD442_25805	COG3279	Response regulator of the LytR AlgR family
GD442_25810	COG2385	sporulation resulting in formation of a cellular spore
GD442_25825	COG4836	Membrane
GD442_25830	COG1007	ATP synthesis coupled electron transport
GD442_25835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GD442_25840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GD442_25850	COG0839	Belongs to the complex I subunit 6 family
GD442_25870	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GD442_25885	COG3300	MHYT domain
GD442_25885	COG5001	Diguanylate cyclase
GD442_25935	COG0356	it plays a direct role in the translocation of protons across the membrane
GD442_25970	COG0698	ribose 5-phosphate isomerase
GD442_25985	COG2259	Doxx family
GD442_25990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GD442_26005	COG0009	L-threonylcarbamoyladenylate synthase
GD442_26040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GD442_26045	COG1494	fructose-1,6-bisphosphatase
GD442_26065	COG4821	SIS domain
GD442_26085	COG1960	acyl-CoA dehydrogenase activity
GD442_26090	COG1960	acyl-CoA dehydrogenase activity
GD442_26095	COG1250	3-hydroxyacyl-CoA dehydrogenase
GD442_26100	COG0183	Belongs to the thiolase family
GD442_26105	COG2181	nitrate reductase activity
GD442_26105	COG0247	lactate metabolic process
GD442_26110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GD442_26120	COG3300	MHYT domain
GD442_26120	COG5001	Diguanylate cyclase
GD442_26135	COG3227	Zinc metalloprotease (Elastase)
GD442_26140	COG2197	response regulator
GD442_26145	COG4585	Histidine kinase
GD442_26150	COG0842	Transport permease protein
GD442_26155	COG1131	(ABC) transporter
GD442_26160	COG0024	Methionine aminopeptidase
GD442_26170	COG2234	aminopeptidase activity
GD442_26195	COG4506	Protein conserved in bacteria
GD442_26200	COG1619	proteins homologs of microcin C7 resistance protein MccF
GD442_26220	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GD442_26225	COG2814	Major facilitator Superfamily
GD442_26230	COG0789	Transcriptional regulator
GD442_26235	COG0584	glycerophosphoryl diester phosphodiesterase
GD442_26240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GD442_26250	COG1994	Peptidase M50
GD442_26260	COG1078	dGTPase activity
GD442_26265	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GD442_26270	COG1120	ATPase activity
GD442_26275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_26280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GD442_26300	COG0280	phosphate acetyltransferase
GD442_26315	COG3773	Cell wall hydrolase
GD442_26325	COG2363	Small membrane protein
GD442_26335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GD442_26340	COG2233	PERMEase
GD442_26345	COG0561	phosphatase activity
GD442_26350	COG2814	Major facilitator Superfamily
GD442_26360	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GD442_26365	COG1131	(ABC) transporter
GD442_26370	COG2755	lipolytic protein G-D-S-L family
GD442_26375	COG1609	Transcriptional regulator
GD442_26385	COG0460	homoserine dehydrogenase
GD442_26405	COG1011	Hydrolase
GD442_26410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GD442_26420	COG2197	response regulator
GD442_26425	COG4585	Histidine kinase
GD442_26425	COG2203	Gaf domain
GD442_26430	COG0351	phosphomethylpyrimidine kinase
GD442_26435	COG3706	GGDEF domain
GD442_26440	COG2879	small protein
GD442_26445	COG1966	Carbon starvation protein
GD442_26450	COG3279	Response regulator of the LytR AlgR family
GD442_26455	COG0477	Major facilitator Superfamily
GD442_26465	COG0438	transferase activity, transferring glycosyl groups
GD442_26480	COG0840	transmembrane signaling receptor activity
GD442_26490	COG1607	acyl-coa hydrolase
GD442_26495	COG1216	Glycosyl transferase, family 2
GD442_26510	COG1216	Glycosyl transferase, family 2
GD442_26520	COG4485	Bacterial membrane protein, YfhO
GD442_26525	COG0463	Glycosyl transferase, family 2
GD442_26530	COG0488	(ABC) transporter
GD442_26535	COG1309	transcriptional regulator
GD442_26540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GD442_26545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GD442_26545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GD442_26550	COG0628	permease
GD442_26570	COG3275	phosphorelay sensor kinase activity
GD442_26575	COG2814	Major facilitator Superfamily
GD442_26580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GD442_26585	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GD442_26605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GD442_26610	COG1272	protein, Hemolysin III
GD442_26630	COG1164	Oligoendopeptidase f
GD442_26640	COG5002	protein histidine kinase activity
GD442_26655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GD442_26660	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GD442_26665	COG4853	Protein conserved in bacteria
GD442_26675	COG5002	protein histidine kinase activity
GD442_26680	COG0745	RESPONSE REGULATOR receiver
GD442_26710	COG0305	Participates in initiation and elongation during chromosome replication
GD442_26720	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GD442_26725	COG4241	membrane
GD442_26745	COG0012	GTP binding
GD442_26750	COG4481	Protein conserved in bacteria
GD442_26755	COG0668	transmembrane transport
GD442_26765	COG1475	DNA binding
GD442_26770	COG1192	Involved in chromosome partitioning
GD442_26795	COG1847	R3H domain protein
GD442_26800	COG0706	membrane insertase activity
GD442_26905	COG0457	Tetratricopeptide repeat
GD442_26940	COG1192	Involved in chromosome partitioning
GD442_26960	COG0551	DNA topoisomerase type I activity
GD442_26960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GD442_26990	COG0741	lytic transglycosylase activity
GD442_26990	COG0791	NLP P60 protein
GD442_27110	COG0156	8-amino-7-oxononanoate synthase activity
GD442_27120	COG1760	l-serine dehydratase
GD442_27285	COG0456	acetyltransferase
GD442_27295	COG5632	N-Acetylmuramoyl-L-alanine amidase
GD442_27295	COG3409	Peptidoglycan-binding domain 1 protein
GD442_27300	COG1522	sequence-specific DNA binding
GD442_27310	COG1388	LysM domain
GD442_27310	COG0791	NLP P60 protein
GD442_27310	COG3103	Sh3 type 3 domain protein
GD442_27330	COG4166	transmembrane transport
GD442_27355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GD442_27465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GD442_27465	COG0551	DNA topoisomerase type I activity
GD442_27525	COG0791	NLP P60 protein
GD442_27525	COG0741	lytic transglycosylase activity