locus-tag class description BGI23_00010 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BGI23_00015 ENOG410848D S4 domain protein YaaA BGI23_00030 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGI23_00070 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BGI23_00105 ENOG4105ZMH deoxynucleoside kinase BGI23_00115 ENOG4105GTG Isochorismatase BGI23_00125 ENOG4108Z6B deaminase BGI23_00135 ENOG4105C6E dna polymerase iii BGI23_00155 ENOG41067KS pro-sigma K processing BGI23_00190 ENOG4105CXN decarboxylase BGI23_00200 ENOG4105FA2 dna polymerase iii BGI23_00205 ENOG4105MA4 psp1 domain protein BGI23_00215 ENOG41060K3 Methyltransferase BGI23_00225 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BGI23_00230 ENOG4105KRN Transcriptional regulator, abrb family BGI23_00240 ENOG4105F8V Hydrolase, tatD family BGI23_00245 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BGI23_00255 ENOG4105XFA sporulation peptidase YabG BGI23_00260 ENOG4105W42 Veg protein BGI23_00275 ENOG4105DFT pur operon repressor BGI23_00280 ENOG4105KME endoribonuclease L-psp BGI23_00295 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BGI23_00310 ENOG4108JA2 transcriptioN-repair coupling factor BGI23_00315 ENOG4108M14 stage v sporulation protein t BGI23_00325 ENOG4108IY2 MazG family BGI23_00330 ENOG41082I2 s4 domain protein BGI23_00335 ENOG4105VYY sporulation protein yabp BGI23_00350 ENOG41060GV RNA binding s1 domain protein BGI23_00375 ENOG4108UGV hypoxanthine phosphoribosyltransferase BGI23_00380 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BGI23_00395 ENOG4105C6T cysteine synthase BGI23_00400 ENOG4105CRQ synthase (Component I) BGI23_00405 ENOG4105DDQ anthranilate synthase BGI23_00410 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BGI23_00415 ENOG4105EEI dihydropteroate synthase BGI23_00420 ENOG4105KRF dihydroneopterin aldolase BGI23_00425 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BGI23_00435 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BGI23_00465 ENOG4108Z0C Uvrb UvrC protein BGI23_00480 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BGI23_00490 ENOG4105CTP PilT protein domain protein BGI23_00510 ENOG4105D7W serine acetyltransferase BGI23_00525 ENOG4105C2N RNA methyltransferase TrmH family group 3 BGI23_00530 ENOG4105M0M Tetracycline resistance protein BGI23_00535 ENOG4105QIV RNA polymerase BGI23_00550 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BGI23_00575 ENOG4107Y49 methyltransferase BGI23_00590 ENOG4105XPM ribosomal protein BGI23_00695 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BGI23_00720 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BGI23_00730 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BGI23_00740 ENOG41067V7 50S ribosomal protein L36 BGI23_00775 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BGI23_00805 ENOG4105D1F ATP-binding protein BGI23_00820 ENOG4108NMV polysaccharide deacetylase BGI23_00885 ENOG4105C8B TIGR00159 family BGI23_00890 ENOG4107U5W ybbr family BGI23_00920 ENOG4108VQT Alpha beta hydrolase fold protein BGI23_00930 ENOG4105CMG Carbohydrate kinase BGI23_00940 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BGI23_00975 ENOG4108PSK reductase BGI23_00980 ENOG4105EE1 crotonyl-CoA reductase BGI23_00990 ENOG4105IQ5 FAD linked oxidase domain protein BGI23_01005 ENOG4105C2C drug resistance transporter, Bcr CflA BGI23_01020 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGI23_01025 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGI23_01030 ENOG4105C3U ABC transporter BGI23_01035 ENOG4108JQ7 (ABC) transporter BGI23_01065 ENOG4108J59 Extracellular solute-binding protein, family 5 BGI23_01070 ENOG4108J59 Extracellular solute-binding protein, family 5 BGI23_01080 ENOG4105II7 pyrroline-5-carboxylate reductase BGI23_01090 ENOG4107XDY Nicotinamide Mononucleotide Transporter BGI23_01100 ENOG4105E0C molybdate abc transporter BGI23_01105 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BGI23_01110 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BGI23_01150 ENOG4105F6E Acyl-transferase BGI23_01175 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BGI23_01190 ENOG4108RE7 deoxyribonuclease BGI23_01200 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BGI23_01225 ENOG4105C5H ABC transporter BGI23_01235 ENOG4105DEF Extracellular solute-binding protein, family 5 BGI23_01245 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGI23_01250 ENOG4105C3U ABC transporter BGI23_01255 ENOG4108JQ7 (ABC) transporter BGI23_01260 ENOG410667J hydrolase BGI23_01300 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BGI23_01305 ENOG4105ERH Fumarylacetoacetate hydrolase BGI23_01315 ENOG4105CUB amino acid BGI23_01325 ENOG4105CPF Cell wall formation (By similarity) BGI23_01330 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BGI23_01355 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BGI23_01360 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BGI23_01370 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BGI23_01470 ENOG4105K8N protein family UPF0079, ATPase BGI23_01475 ENOG41072GX Peptidase M22 Glycoprotease BGI23_01480 ENOG410801F ribosomal-protein-alanine acetyltransferase BGI23_01490 ENOG4105C5H ABC transporter BGI23_01505 ENOG4108TYN CAAX amino terminal protease family protein BGI23_01535 ENOG4105C7N Xanthine uracil vitamin C permease BGI23_01545 ENOG4105BZU Histidine kinase BGI23_01570 ENOG4107ZXU DSBA oxidoreductase BGI23_01640 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGI23_01660 ENOG4105SX7 Transporter BGI23_01685 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BGI23_01690 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BGI23_01695 ENOG4105C83 adenylosuccinate lyase BGI23_01705 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BGI23_01730 ENOG4108V3E phosphoribosylglycinamide formyltransferase BGI23_01740 ENOG4105C12 Phosphoribosylglycinamide synthetase BGI23_01770 ENOG4105C4R Atp-dependent dna helicase BGI23_01800 ENOG4108W2Y isochorismatase BGI23_01810 ENOG4108UMI ABC transporter, permease BGI23_01815 ENOG4105D01 (LipO)protein BGI23_01835 ENOG410834F Transcriptional regulator BGI23_01840 ENOG4107I77 yiaA/B two helix domain BGI23_01860 ENOG4105CBD Diacylglycerol kinase BGI23_01865 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BGI23_01870 ENOG4108JPW Aminotransferase BGI23_01880 ENOG4105C26 Dehydrogenase BGI23_01885 ENOG4105KPY Small multidrug resistance protein BGI23_01900 ENOG4105D9N nucleoside BGI23_01905 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BGI23_01915 ENOG4105BZU Histidine kinase BGI23_01925 ENOG4108W15 Protein of unknown function (DUF1456) BGI23_01940 ENOG4105DTQ mandelate racemase muconate lactonizing BGI23_01950 ENOG4105DFD Na H antiporter BGI23_01970 ENOG4105D3R alkyl hydroperoxide reductase BGI23_01975 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) BGI23_01985 ENOG4107W7X Aldolase BGI23_01990 ENOG4105EHG Permease protein BGI23_01995 ENOG4105DQ5 transport system permease protein BGI23_02000 ENOG4108V5C ABC transporter BGI23_02005 ENOG4105CAY ferredoxin--nadp reductase BGI23_02035 ENOG4105D7V transposase BGI23_02045 ENOG4106UIA BGI23_02050 ENOG4106UIA BGI23_02080 ENOG410756H nucleotidyltransferase BGI23_02090 ENOG4105DQ6 Transposase BGI23_02095 ENOG4105D2S major facilitator superfamily BGI23_02110 ENOG4105E5Q amino acid AbC transporter BGI23_02115 ENOG4105EAB amino acid AbC transporter BGI23_02125 ENOG4105C8Q Methyl-accepting chemotaxis BGI23_02150 ENOG4105C5B carbamate kinase BGI23_02170 ENOG4105CI1 PTS System BGI23_02205 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BGI23_02220 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component BGI23_02225 ENOG4107Z6I Thiamine biosynthesis protein BGI23_02240 ENOG4105C5H ABC transporter BGI23_02270 ENOG41062JF Transcriptional regulator BGI23_02285 ENOG4105DEU major facilitator superfamily BGI23_02315 ENOG4108N0M stress protein BGI23_02320 ENOG4106FN3 tellurium resistance protein BGI23_02325 ENOG4106FN3 tellurium resistance protein BGI23_02330 ENOG4107TS3 membrane protein, TerC BGI23_02335 ENOG4108TTB tellurium resistance protein BGI23_02355 ENOG4105KJF protein tyrosine phosphatase BGI23_02365 ENOG4107U9T Pfam:Ribonuclease_BN BGI23_02370 ENOG4105C59 p-type ATPase BGI23_02375 ENOG4108IPJ Membrane BGI23_02390 ENOG4105C3F Signal peptidase i BGI23_02400 ENOG4107ZTW SNARE associated Golgi BGI23_02415 ENOG410606W general stress protein BGI23_02420 ENOG4105UPD Calcium Proton BGI23_02455 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BGI23_02470 ENOG4108JUB Transcriptional regulator BGI23_02480 ENOG4108IQI permease BGI23_02515 ENOG4105CSV Glutaminase BGI23_02525 ENOG4108A04 Beta-lactamase BGI23_02545 ENOG4105CKK Glycosyl transferase, family 2 BGI23_02550 ENOG4107QQG Dehydrogenase BGI23_02555 ENOG4105C3I Nad-dependent epimerase dehydratase BGI23_02575 ENOG4105F1A Pyruvate formate-lyase BGI23_02595 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BGI23_02600 ENOG4105ECP epimerase BGI23_02630 ENOG41067AE Membrane-bound metal-dependent hydrolase BGI23_02635 ENOG4105CEN a g-specific adenine glycosylase BGI23_02640 ENOG4106BXE BGI23_02660 ENOG4105BZ1 (ABC) transporter BGI23_02665 ENOG4107NBY Membrane BGI23_02670 ENOG4105CBC glutamate synthase BGI23_02680 ENOG4108IUW ABC transporter BGI23_02700 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BGI23_02705 ENOG4105G5W regulator Fur family BGI23_02810 ENOG4105DQ6 Transposase BGI23_02825 ENOG4108JQC penicillin-binding protein 1A BGI23_02830 ENOG4108R9S DSBA oxidoreductase BGI23_02840 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BGI23_02850 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BGI23_02855 ENOG4105BZU Histidine kinase BGI23_02865 ENOG4105CYN Serine protein kinase BGI23_02890 ENOG4105C94 Transporter BGI23_02905 ENOG4105DZ6 Band 7 protein BGI23_02915 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BGI23_02920 ENOG4108V9W transcriptional regulatory protein BGI23_02925 ENOG4105D4T Citrate transporter BGI23_02945 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BGI23_02950 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGI23_02955 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BGI23_02960 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BGI23_02965 ENOG4105BZ7 extracellular solute-binding protein family 1 BGI23_02970 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BGI23_02975 ENOG4108STX response regulator BGI23_02980 ENOG4105US7 Histidine kinase BGI23_03005 ENOG4108MRH transcriptional regulatory protein BGI23_03015 ENOG4105C6K Malic enzyme BGI23_03025 ENOG4108UZ3 Transporter BGI23_03030 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGI23_03040 ENOG4105BZU Histidine kinase BGI23_03045 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_03055 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BGI23_03060 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BGI23_03065 ENOG4108JB9 formate dehydrogenase BGI23_03090 ENOG4105CUB amino acid BGI23_03100 ENOG4105C59 p-type ATPase BGI23_03105 ENOG4105DAP Nicotinate phosphoribosyltransferase BGI23_03140 ENOG41073R8 VanW family BGI23_03145 ENOG4108KGH TRANSCRIPTIONal BGI23_03150 ENOG4105D9N nucleoside BGI23_03155 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BGI23_03160 ENOG4105C37 (CBS) domain BGI23_03165 ENOG4108IJ0 Aspartate ammonia-lyase BGI23_03170 ENOG4105DAA L-lactate BGI23_03185 ENOG4105DUX Transporter BGI23_03190 ENOG4108MES Periplasmic binding protein BGI23_03195 ENOG4105DQ5 transport system permease protein BGI23_03200 ENOG4108IHU transport system permease protein BGI23_03205 ENOG4105E0A ABC, transporter BGI23_03210 ENOG4105DMQ Methyltransferase BGI23_03220 ENOG4105EXW epimerase dehydratase BGI23_03230 ENOG4107T89 von Willebrand factor, type A BGI23_03235 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BGI23_03240 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BGI23_03255 ENOG4105BZU Histidine kinase BGI23_03260 ENOG4105D5Q Arginine ornithine antiporter BGI23_03265 ENOG4107414 GntR family transcriptional regulator BGI23_03270 ENOG4105C5Y PTS System BGI23_03275 ENOG4105CG3 alpha amylase, catalytic region BGI23_03290 ENOG4105E1K spore germination protein BGI23_03300 ENOG4105CRN Aminoglycoside phosphotransferase BGI23_03305 ENOG4105BZG amino acid carrier protein BGI23_03310 ENOG4105CDA abc transporter atp-binding protein BGI23_03315 ENOG4105CT1 (ABC) transporter BGI23_03320 ENOG4105EAD ABC transporter BGI23_03325 ENOG4105DRP amino acid AbC transporter BGI23_03330 ENOG4108IQI permease BGI23_03345 ENOG4105GFR rna polymerase sigma factor BGI23_03355 ENOG4105D29 Helix-turn-helix type 11 domain protein BGI23_03360 ENOG4105NAE bifunctional deaminase-reductase domain protein BGI23_03365 ENOG4105BZU Histidine kinase BGI23_03380 ENOG4105CHH sulfate transporter BGI23_03385 ENOG41068KF Universal stress protein BGI23_03395 ENOG4105DEF Extracellular solute-binding protein, family 5 BGI23_03405 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGI23_03410 ENOG4108JQ7 (ABC) transporter BGI23_03420 ENOG4105CXY transporter BGI23_03425 ENOG41067TZ transcriptional regulator, MarR family BGI23_03430 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGI23_03435 ENOG4105ETE Transcriptional regulator (LacI family BGI23_03440 ENOG4108RVA ribokinase BGI23_03450 ENOG4105C2J ABC transporter BGI23_03455 ENOG4105CNN ABC, transporter BGI23_03460 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BGI23_03465 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BGI23_03525 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BGI23_03530 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BGI23_03535 ENOG41069ER domain protein BGI23_03540 ENOG4105VZ8 Transcriptional regulator BGI23_03545 ENOG4107D63 BGI23_03555 ENOG4105DUX Transporter BGI23_03575 ENOG4105C85 amino acid BGI23_03580 ENOG4105C7N Xanthine uracil vitamin C permease BGI23_03595 ENOG4105MA6 gCN5-related N-acetyltransferase BGI23_03620 ENOG4105BZ9 Cytochrome C oxidase, subunit I BGI23_03625 ENOG4105E2S oxidase) subunit II BGI23_03645 ENOG4106CAD Protein of unknown function (DUF3311) BGI23_03650 ENOG4105E1V na solute symporter BGI23_03665 ENOG4108NHD germination protein BGI23_03675 ENOG4105CE1 Ferrous iron transport protein b BGI23_03680 ENOG4105CE1 Ferrous iron transport protein b BGI23_03685 ENOG4105CE1 Ferrous iron transport protein b BGI23_03690 ENOG4105CVA phosphate BGI23_03695 ENOG4105C8U phosphate abc transporter BGI23_03700 ENOG4105E2Z phosphate ABC transporter (Permease BGI23_03830 ENOG41080XQ Signal transduction protein with cbs domains BGI23_03855 ENOG4105ETU transcriptional activator (TenA BGI23_03865 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BGI23_03875 ENOG4108VEU Thiamine monophosphate synthase BGI23_03880 ENOG41080HI glycine oxidase BGI23_03895 ENOG4105D06 uba thif-type nad fad binding protein BGI23_03900 ENOG4105DWF phosphomethylpyrimidine kinase BGI23_03950 ENOG4108INS Transcriptional regulator BGI23_03960 ENOG4105C7N Xanthine uracil vitamin C permease BGI23_03970 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BGI23_03985 ENOG4105K63 Thioredoxin BGI23_04005 ENOG4108B31 Spore germination protein BGI23_04025 ENOG4107Y03 Nitroreductase BGI23_04030 ENOG4105ED1 spovr family BGI23_04050 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase BGI23_04055 ENOG4105XTG Pfam:DUF156 BGI23_04060 ENOG4105VFE sira family BGI23_04065 ENOG4107TPS domain protein BGI23_04070 ENOG4105VFE sira family BGI23_04075 ENOG41085GJ domain protein BGI23_04085 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BGI23_04090 ENOG41087NI Sulfite exporter TauE/SafE BGI23_04100 ENOG4108KGH TRANSCRIPTIONal BGI23_04125 ENOG4105EMD TRANSCRIPTIONal BGI23_04130 ENOG4105VCP PTS System BGI23_04135 ENOG4105VZJ PTS System BGI23_04160 ENOG41069ER domain protein BGI23_04165 ENOG4107RBB ABC transporter, permease BGI23_04170 ENOG4105C19 ABC transporter BGI23_04205 ENOG4105WEF catalase BGI23_04240 ENOG4107T5V SNARE associated Golgi BGI23_04280 ENOG4105CUB amino acid BGI23_04285 ENOG4107RWR Sodium hydrogen exchanger BGI23_04295 ENOG4106KNT transcriptional regulator BGI23_04335 ENOG4108YXU transcriptional regulator AsnC family BGI23_04345 ENOG4105KPY Small multidrug resistance protein BGI23_04350 ENOG4105KPY Small multidrug resistance protein BGI23_04385 ENOG4105C19 ABC transporter BGI23_04390 ENOG4107RBB ABC transporter, permease BGI23_04395 ENOG4105C19 ABC transporter BGI23_04425 ENOG4105NF4 modulator of drug activity BGI23_04435 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BGI23_04440 ENOG4105E5W Transporter BGI23_04450 ENOG4107RKG DJ-1/PfpI family BGI23_04455 ENOG4105CH6 catalase BGI23_04465 ENOG4105D5Q Arginine ornithine antiporter BGI23_04470 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BGI23_04480 ENOG4105C26 Dehydrogenase BGI23_04490 ENOG4105BZ1 (ABC) transporter BGI23_04495 ENOG4105BZ1 (ABC) transporter BGI23_04505 ENOG4105DRP amino acid AbC transporter BGI23_04510 ENOG4105CDA abc transporter atp-binding protein BGI23_04525 ENOG410839P BGI23_04560 ENOG4107FQX Alpha-acetolactate decarboxylase BGI23_04580 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BGI23_04585 ENOG4105D4P Coproporphyrinogen iii oxidase BGI23_04600 ENOG4105CHH sulfate transporter BGI23_04635 ENOG4106AKK s-layer domain-containing protein BGI23_04645 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BGI23_04650 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BGI23_04665 ENOG4105CGU Enoyl-CoA hydratase BGI23_04685 ENOG4105DER m42 family BGI23_04720 ENOG4105CSH Transporter BGI23_04730 ENOG4108MRH transcriptional regulatory protein BGI23_04815 ENOG4105CDU Replicative dna helicase BGI23_04850 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGI23_04910 ENOG4107P5I polyketide synthase BGI23_04915 ENOG4108IG5 Transcriptional regulator BGI23_04930 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BGI23_04975 ENOG4105CMT Dihydroxyacetone kinase BGI23_04985 ENOG4105CMT Dihydroxyacetone kinase BGI23_05020 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BGI23_05095 ENOG4105WN5 stage II sporulation protein BGI23_05105 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGI23_05115 ENOG4108MJI response regulator BGI23_05120 ENOG4105BZU Histidine kinase BGI23_05125 ENOG4105BZU Histidine kinase BGI23_05150 ENOG4105K8R UPF0145 protein BGI23_05165 ENOG4105ENE Histidine kinase BGI23_05170 ENOG4108VB1 regulatoR BGI23_05200 ENOG4107VRP DNA repair exonuclease BGI23_05205 ENOG4106D4I domain protein BGI23_05245 ENOG4108MUZ hydrolase BGI23_05270 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BGI23_05285 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BGI23_05300 ENOG4105EMN RNA polymerase sigma factor BGI23_05310 ENOG4105CNI cell division protein FtsW BGI23_05320 ENOG4105EEM helicase BGI23_05325 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BGI23_05355 ENOG4105K59 histidine triad (HIT) protein BGI23_05445 ENOG410905X membrane-flanked domain protein BGI23_05450 ENOG4105CKV Membrane BGI23_05475 ENOG410905X membrane-flanked domain protein BGI23_05480 ENOG4105CKV Membrane BGI23_05485 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BGI23_05490 ENOG4105BZ4 penicillin-binding protein BGI23_05500 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BGI23_05505 ENOG4105C1Q protoporphyrinogen oxidase BGI23_05535 ENOG4105NA0 Transcriptional regulator BGI23_05550 ENOG4105ECB domain protein BGI23_05575 ENOG4105D29 Helix-turn-helix type 11 domain protein BGI23_05585 ENOG4106AXD BGI23_05590 ENOG4108RQ5 Beta-lactamase domain-containing protein BGI23_05595 ENOG4105DF9 Lipoate-protein, ligase BGI23_05605 ENOG4105CEY Amp-dependent synthetase and ligase BGI23_05620 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) BGI23_05630 ENOG4105ENX hydrolase BGI23_05635 ENOG4107RN3 metallophosphoesterase BGI23_05640 ENOG4107TVP HD domain protein BGI23_05655 ENOG41086D8 Transcriptional regulator BGI23_05665 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGI23_05690 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BGI23_05695 ENOG4105C8Q Methyl-accepting chemotaxis BGI23_05715 ENOG4105ZU5 s-layer protein BGI23_05720 ENOG4107QP3 malate synthase g BGI23_05735 ENOG4105VEQ Cold shock protein BGI23_05750 ENOG4105XVF Competence transcription factor BGI23_05815 ENOG4105ERH Fumarylacetoacetate hydrolase BGI23_05840 ENOG4105CAQ asparagine synthetase BGI23_05845 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BGI23_05850 ENOG4105CH6 catalase BGI23_05855 ENOG4105BZU Histidine kinase BGI23_05885 ENOG4105QNR S1 RNA binding domain protein BGI23_05890 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BGI23_05900 ENOG4107AYK membrAne BGI23_05905 ENOG41073B9 BGI23_05915 ENOG4108KP7 hydrolase BGI23_05955 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BGI23_05960 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BGI23_05975 ENOG4105C31 Tryptophanyl-tRNA synthetase BGI23_05990 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGI23_05995 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGI23_06005 ENOG4108JQ7 (ABC) transporter BGI23_06010 ENOG4105UQX Mate efflux family protein BGI23_06035 ENOG4108ZCF integral membrane protein BGI23_06045 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BGI23_06055 ENOG4105DPN Oligoendopeptidase f BGI23_06070 ENOG4108Z18 K06886 hemoglobin BGI23_06075 ENOG4105MIX Adenylate cyclase BGI23_06080 ENOG4106EFP UPF0738 protein BGI23_06095 ENOG4105EMS pseudouridine synthase BGI23_06115 ENOG4105K64 Glycosyl transferase, family 2 BGI23_06135 ENOG4107TVC Glycosyl transferase, family 2 BGI23_06155 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BGI23_06160 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BGI23_06170 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BGI23_06245 ENOG4105CK7 Sodium proline symporter BGI23_06255 ENOG4105CRQ synthase (Component I) BGI23_06260 ENOG4105DDQ anthranilate synthase BGI23_06345 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BGI23_06365 ENOG4105C7S Dehydrogenase BGI23_06375 ENOG4105VZ8 Transcriptional regulator BGI23_06455 ENOG4105VTR Integrase BGI23_06495 ENOG4105DZ1 carboxypeptidase BGI23_06500 ENOG4105VFR signal peptidase BGI23_06535 ENOG4105C26 Dehydrogenase BGI23_06545 ENOG4105F38 ABC transporter, permease BGI23_06550 ENOG4105D38 putrescine abc transporter BGI23_06555 ENOG4107RUE extracellular solute-binding protein family 1 BGI23_06565 ENOG4105EYF MMPL domain protein BGI23_06575 ENOG4108YBP pseudouridine synthase BGI23_06585 ENOG4105K4I Scp-like extracellular BGI23_06590 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BGI23_06595 ENOG4105CQB FAD linked oxidase domain protein BGI23_06610 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_06615 ENOG4105BZU Histidine kinase BGI23_06620 ENOG4105JXH GntR family transcriptional regulator BGI23_06640 ENOG4106A3R peptidase BGI23_06650 ENOG4108QTI )-transporter BGI23_06655 ENOG4107TS3 membrane protein, TerC BGI23_06660 ENOG4105CZN Potassium uptake protein BGI23_06665 ENOG410681C small acid-soluble spore protein BGI23_06670 ENOG4108Z7G MaoC domain protein dehydratase BGI23_06690 ENOG4105CHR reductase BGI23_06720 ENOG4105C4Y ABC transporter BGI23_06725 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGI23_06730 ENOG4107RCV ABC transporter, permease BGI23_06750 ENOG4105E98 transcriptional regulator DeoR family BGI23_06765 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BGI23_06775 ENOG4105PXI polysaccharide deacetylase BGI23_06785 ENOG4105BZU Histidine kinase BGI23_06790 ENOG41090MY MarR family Transcriptional regulator BGI23_06800 ENOG4106DF1 BGI23_06810 ENOG4105BZU Histidine kinase BGI23_06820 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BGI23_06825 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BGI23_06870 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BGI23_06885 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BGI23_06890 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BGI23_06895 ENOG4105CZV ABC transporter BGI23_06905 ENOG4105CJ1 ABC, transporter BGI23_06940 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BGI23_06945 ENOG4105EA8 2-Nitropropane dioxygenase BGI23_06950 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BGI23_06960 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BGI23_06985 ENOG4105NQC Flavodoxin BGI23_07020 ENOG4107QMU Mate efflux family protein BGI23_07055 ENOG4105CZN Potassium uptake protein BGI23_07060 ENOG41063Y9 BGI23_07065 ENOG4105KBJ sporulation protein ytfj BGI23_07095 ENOG4105CM2 brancheD-chain amino acid aminotransferase BGI23_07100 ENOG4105C7K acetolactate synthase BGI23_07105 ENOG4108ZP8 Acetolactate synthase small subunit BGI23_07180 ENOG4107RVV histidinol phosphate phosphatase, hisj family BGI23_07195 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BGI23_07200 ENOG4105E0M Sulfatase BGI23_07210 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BGI23_07230 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BGI23_07235 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BGI23_07245 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BGI23_07250 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BGI23_07255 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BGI23_07265 ENOG4105C8J )-transporter BGI23_07285 ENOG4105DFD Na H antiporter BGI23_07305 ENOG4105ENE Histidine kinase BGI23_07310 ENOG4105WH1 Two component transcriptional regulator luxr family BGI23_07330 ENOG41089UC methyltransferase, type 11 BGI23_07355 ENOG4105DQ6 Transposase BGI23_07360 ENOG4105IYK transposase BGI23_07390 ENOG4105CJ3 phosphate transporter BGI23_07395 ENOG4107GRR phosphate transport regulator BGI23_07400 ENOG4105BZ4 penicillin-binding protein BGI23_07415 ENOG4105BZU Histidine kinase BGI23_07420 ENOG4105I3N Conserved Protein BGI23_07435 ENOG4105BZU Histidine kinase BGI23_07440 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BGI23_07465 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BGI23_07470 ENOG4105DZ1 carboxypeptidase BGI23_07475 ENOG4108JIC nucleoside recognition domain protein BGI23_07485 ENOG4105FE9 pseudouridine synthase BGI23_07495 ENOG4107TWT Cytochrome c biogenesis protein BGI23_07500 ENOG4105CRE cytochrome C BGI23_07505 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_07510 ENOG4105BZU Histidine kinase BGI23_07515 ENOG4108WBT adenosyltransferase BGI23_07520 ENOG41063SB peptidase BGI23_07530 ENOG4108SAX Membrane BGI23_07545 ENOG4105C9U ATP-dependent DNA helicase RecQ BGI23_07550 ENOG4105I7S Abortive infection protein BGI23_07560 ENOG4107RGJ metallophosphoesterase BGI23_07565 ENOG4107X2D transcriptional regulator, merr family BGI23_07570 ENOG4108S6Z Negative regulator of genetic competence BGI23_07595 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BGI23_07600 ENOG4105HDK L-asparaginase BGI23_07635 ENOG4105S2F BGI23_07640 ENOG41065D1 BGI23_07670 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BGI23_07685 ENOG4105XXQ heptaprenyl diphosphate synthase component I BGI23_07695 ENOG4105EAH synthase BGI23_07715 ENOG4105CIH Imidazole acetol-phosphate transaminase BGI23_07720 ENOG41068YB TPR repeat-containing protein BGI23_07735 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BGI23_07740 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BGI23_07775 ENOG4108JYZ YitT family BGI23_07780 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BGI23_07795 ENOG4105FJR Lmbe family BGI23_07800 ENOG4105CPK Glycosyl transferase (Group 1 BGI23_07840 ENOG4105DVT helicase BGI23_07845 ENOG4105YAC BGI23_07865 ENOG4105CSM endonuclease III BGI23_07875 ENOG4105BZ4 penicillin-binding protein BGI23_07930 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BGI23_07940 ENOG4105DVT helicase BGI23_07945 ENOG4105CTD carboxy-peptidase BGI23_07955 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BGI23_07965 ENOG4105C2W permease BGI23_07970 ENOG4105DHF Membrane BGI23_07975 ENOG410890F Dynamin family BGI23_07985 ENOG4108W0I acetyltransferase BGI23_07995 ENOG4105KHC sulfurtransferase BGI23_08020 ENOG4106032 Glutathionylspermidine synthase BGI23_08080 ENOG4105CPK Glycosyl transferase (Group 1 BGI23_08095 ENOG4108SZE gCN5-related N-acetyltransferase BGI23_08115 ENOG41081VK Ribonuclease BGI23_08180 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGI23_08190 ENOG4107RWR Sodium hydrogen exchanger BGI23_08195 ENOG4105CN5 Metallo-Beta-Lactamase BGI23_08200 ENOG4108Z5V transcriptional regulator, merr family BGI23_08210 ENOG4105H67 Protein of unknown function (DUF421) BGI23_08215 ENOG41080C8 DUF218 domain BGI23_08280 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BGI23_08290 ENOG4107R0U MotA TolQ exbB proton channel BGI23_08295 ENOG4105ER2 Ompa motb domain protein BGI23_08300 ENOG4107YTP response regulator receiver protein BGI23_08305 ENOG4105CBS Chea signal transduction histidine kinase BGI23_08310 ENOG4105DD5 Flagellar motor switch protein BGI23_08325 ENOG4105BZU Histidine kinase BGI23_08345 ENOG4105E1Q flagellar hook-associated protein BGI23_08350 ENOG4105DTJ flagellar hook-associated protein BGI23_08355 ENOG410804A Flagellar hook-associated 2 domain-containing protein BGI23_08370 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BGI23_08375 ENOG4108ZC9 flagellar basal-body rod protein flgc BGI23_08380 ENOG41075Z6 flagellar hook-basal body complex protein fliE BGI23_08385 ENOG4107U2N Flagellar M-ring protein BGI23_08390 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BGI23_08420 ENOG4105BZE flagellar hook protein, FlgE BGI23_08435 ENOG4107R88 Chemotaxis protein (CheV) BGI23_08450 ENOG4107ZIC Glycerol-3-phosphate cytidylyltransferase BGI23_08455 ENOG4107VDP teichoic acid biosynthesis BGI23_08460 ENOG4105I03 Flagellin BGI23_08465 ENOG4105E4C Lytic transglycosylase catalytic BGI23_08475 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BGI23_08480 ENOG4105DD5 Flagellar motor switch protein BGI23_08490 ENOG4105CN7 Flagellar biosynthetic protein FliP BGI23_08495 ENOG4105VS8 Flagellar biosynthetic protein fliq BGI23_08505 ENOG4105D00 flagellar biosynthetic protein flhB BGI23_08510 ENOG4105D7B Flagellar biosynthesis protein flha BGI23_08515 ENOG4105FZW flagellar biosynthesis regulator FlhF BGI23_08520 ENOG4105KTQ flagellar basal-body rod protein BGI23_08525 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BGI23_08550 ENOG41062JF Transcriptional regulator BGI23_08570 ENOG4105KAC Antibiotic biosynthesis monooxygenase BGI23_08595 ENOG4105DUM transcriptional regulator, lysR family BGI23_08600 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGI23_08605 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BGI23_08610 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BGI23_08615 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BGI23_08630 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BGI23_08655 ENOG4105CVJ phosphoglycerate mutase BGI23_08675 ENOG4105K56 Transcriptional regulator BGI23_08685 ENOG4105CAQ asparagine synthetase BGI23_08705 ENOG4105PGM cation diffusion facilitator family transporter BGI23_08715 ENOG4105DRR Transcriptional regulator, GntR family BGI23_08720 ENOG4108UZ3 Transporter BGI23_08730 ENOG4105DFD Na H antiporter BGI23_08735 ENOG4105C9Q fumarate hydratase class II BGI23_08755 ENOG4107QJQ Mate efflux family protein BGI23_08760 ENOG4105EC3 peptidase S51, dipeptidase E BGI23_08805 ENOG4107A6P BGI23_08820 ENOG4107E54 Small Multidrug Resistance protein BGI23_08835 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BGI23_08845 ENOG4106BRA Membrane BGI23_08880 ENOG4105CJ1 ABC, transporter BGI23_08900 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BGI23_08910 ENOG4108IJ0 Aspartate ammonia-lyase BGI23_08915 ENOG4105C6K Malic enzyme BGI23_08930 ENOG4105C0D helicase BGI23_08950 ENOG41067QW Transcriptional regulator BGI23_08980 ENOG4105FVX BGI23_09020 ENOG4105CSR polyphosphate kinase 2 BGI23_09025 ENOG4105U3E Transcriptional regulator BGI23_09035 ENOG4105DXI Major Facilitator superfamily BGI23_09050 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BGI23_09065 ENOG4105EU0 Major facilitator Superfamily BGI23_09070 ENOG4105C6T cysteine synthase BGI23_09090 ENOG4105C8J )-transporter BGI23_09100 ENOG4105X5K response regulator receiver protein BGI23_09105 ENOG4105H67 Protein of unknown function (DUF421) BGI23_09120 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BGI23_09125 ENOG4105CM2 brancheD-chain amino acid aminotransferase BGI23_09130 ENOG4105C7K acetolactate synthase BGI23_09150 ENOG4105C7B Threonine dehydratase BGI23_09175 ENOG4105C6X Major Facilitator BGI23_09180 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BGI23_09190 ENOG4105DY9 regulatoR BGI23_09195 ENOG4105CYC Transferase BGI23_09255 ENOG41068WN BGI23_09260 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGI23_09280 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BGI23_09295 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BGI23_09305 ENOG4105C0X amino acid BGI23_09330 ENOG4107RHR regulatoR BGI23_09340 ENOG4105D9N nucleoside BGI23_09345 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BGI23_09365 ENOG4107RAQ aminopeptidase BGI23_09405 ENOG4108T5E Copper resistance protein BGI23_09410 ENOG4105KTB nuclear export factor GLE1 BGI23_09415 ENOG4107RT3 EamA-like transporter family BGI23_09420 ENOG4105GZI Transcriptional regulator BGI23_09425 ENOG4108Z40 Transcriptional regulator BGI23_09430 ENOG4107ZXU DSBA oxidoreductase BGI23_09435 ENOG4108TVJ Nitroreductase BGI23_09445 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BGI23_09450 ENOG4106F5Q Membrane BGI23_09455 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BGI23_09465 ENOG4105CKI cobalamin synthesis protein BGI23_09485 ENOG4108Z7G MaoC domain protein dehydratase BGI23_09490 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BGI23_09500 ENOG4105C0Z ABC transporter BGI23_09505 ENOG4108IV0 ABC, transporter BGI23_09510 ENOG4105C32 Amino acid ABC transporter (Permease) BGI23_09530 ENOG4105MDS 4-oxalocrotonate tautomerase BGI23_09550 ENOG4105C4M (Ubiquinol oxidase) subunit I BGI23_09555 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BGI23_09560 ENOG4108JJ9 ABC, transporter BGI23_09565 ENOG4108JJ8 (ABC) transporter BGI23_09575 ENOG4105K64 Glycosyl transferase, family 2 BGI23_09585 ENOG4108UT6 Transferase hexapeptide repeat containing protein BGI23_09640 ENOG4105BZ1 (ABC) transporter BGI23_09645 ENOG4105EFI regulatoR BGI23_09650 ENOG4105BZU Histidine kinase BGI23_09665 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BGI23_09670 ENOG4108ZJ4 polysaccharide deacetylase BGI23_09690 ENOG4105D6E homoserine dehydrogenase BGI23_09715 ENOG4108KGH TRANSCRIPTIONal BGI23_09725 ENOG4107VMI polysaccharide deacetylase BGI23_09735 ENOG4105KT7 mgtC SapB transporter BGI23_09740 ENOG4105VRR gCN5-related N-acetyltransferase BGI23_09745 ENOG4105YWU small acid-soluble spore protein BGI23_09755 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BGI23_09805 ENOG4105KRN Transcriptional regulator, abrb family BGI23_09815 ENOG4105CKN UDP-glucose-hexose-1-phosphate uridylyltransferase BGI23_09820 ENOG4105YVS arsR family transcriptional regulator BGI23_09825 ENOG4105CPC Aldo Keto reductase BGI23_09830 ENOG4107XZQ multidrug resistance protein BGI23_09870 ENOG4108K88 Membrane BGI23_09875 ENOG4108WPJ Ferritin-like domain BGI23_09890 ENOG4105DEN Luciferase family BGI23_09910 ENOG4107QM2 Aldo Keto reductase BGI23_09915 ENOG4105CKI cobalamin synthesis protein BGI23_09925 ENOG4105DSE periplasmic solute binding protein BGI23_09935 ENOG4105K4T epimerase BGI23_09945 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BGI23_09970 ENOG4105CVJ phosphoglycerate mutase BGI23_09990 ENOG4107T5V SNARE associated Golgi BGI23_10005 ENOG4108PJD permease BGI23_10015 ENOG4108S4H thioesterase Superfamily protein BGI23_10020 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BGI23_10040 ENOG4105SXS Protein of unknown function (DUF456) BGI23_10045 ENOG4105C37 (CBS) domain BGI23_10065 ENOG4108Z7R Chaperone CsaA BGI23_10085 ENOG4108ZRV stage ii sporulation protein p BGI23_10095 ENOG4108VXD carboxy-peptidase BGI23_10130 ENOG4108X4Q Hydrolase BGI23_10140 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BGI23_10145 ENOG4107RBS Methyltransferase BGI23_10160 ENOG41087PP glycosyltransferase MGT family BGI23_10165 ENOG4108JYZ YitT family BGI23_10170 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGI23_10200 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BGI23_10230 ENOG4105KBJ sporulation protein ytfj BGI23_10255 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BGI23_10280 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BGI23_10290 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BGI23_10295 ENOG4105EMN RNA polymerase sigma factor BGI23_10315 ENOG4105CNW domain protein BGI23_10325 ENOG4108V06 Glutathione peroxidase BGI23_10340 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BGI23_10350 ENOG4108IUE nitrate reductase beta subunit BGI23_10355 ENOG4105R3A Nitrate reductase BGI23_10365 ENOG4107V6Q Cyclic nucleotide-binding domain BGI23_10370 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BGI23_10375 ENOG4105D06 uba thif-type nad fad binding protein BGI23_10380 ENOG4105CVM Molybdenum cofactor synthesis domain protein BGI23_10385 ENOG4108ZAF Molybdopterin BGI23_10400 ENOG4105GAK amidohydrolase 2 BGI23_10410 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BGI23_10415 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BGI23_10420 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BGI23_10425 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BGI23_10430 ENOG4108IFG nitrite reductase, (NAD(P)H) BGI23_10435 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BGI23_10470 ENOG4105MCT stage V sporulation protein S BGI23_10520 ENOG4105C5H ABC transporter BGI23_10535 ENOG4108UUM single-stranded DNA-binding protein BGI23_10565 ENOG4107YX5 Pfam:DUF548 BGI23_10600 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BGI23_10605 ENOG4105C5S asparaginyl-tRNA synthetase BGI23_10625 ENOG4105EC2 ftsk spoIIIe BGI23_10685 ENOG4105C8J )-transporter BGI23_10705 ENOG4107XGZ Hydrolase BGI23_10710 ENOG4105CY2 Citrate transporter BGI23_10715 ENOG4105C0A alcohol dehydrogenase BGI23_10730 ENOG4105KD7 acetyltransferase BGI23_10735 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BGI23_10760 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BGI23_10780 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) BGI23_10800 ENOG4107RVG penicillin-binding protein BGI23_10805 ENOG4107XM6 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BGI23_10810 ENOG4105E9Q Acyl-transferase BGI23_10815 ENOG4108UT2 hemolysin iii BGI23_10825 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BGI23_10835 ENOG4108RCR degv family BGI23_10840 ENOG4105D7V transposase BGI23_10845 ENOG4105E8R UPF0173 metal-dependent hydrolase BGI23_10850 ENOG4108KF3 Electron transport protein SCO1 SenC BGI23_10855 ENOG4107Y70 Heat shock protein BGI23_10860 ENOG4105CAQ asparagine synthetase BGI23_10880 ENOG4108MES Periplasmic binding protein BGI23_10885 ENOG4105F0I Aminotransferase BGI23_10910 ENOG4107Y70 Heat shock protein BGI23_10915 ENOG4105D8X mechanosensitive ion channel BGI23_10920 ENOG4105BZU Histidine kinase BGI23_10925 ENOG4105WH1 Two component transcriptional regulator luxr family BGI23_10955 ENOG4105CMG Carbohydrate kinase BGI23_10990 ENOG4108IJ8 ABC transporter BGI23_10995 ENOG4105E90 ABC transporter BGI23_11030 ENOG4105C37 (CBS) domain BGI23_11055 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGI23_11070 ENOG4107S4Y M20 DapE family protein YgeY BGI23_11075 ENOG4108TSC N-acetyltransferase BGI23_11080 ENOG4108JUB Transcriptional regulator BGI23_11085 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BGI23_11125 ENOG4108N23 SpoOM-related protein BGI23_11130 ENOG410841Q phosphoesterase PA-phosphatase related protein BGI23_11140 ENOG4105SZ6 Thioredoxin BGI23_11150 ENOG4108TFU terminase (Small subunit) BGI23_11180 ENOG4108AEY RNA polymerase sigma factor BGI23_11210 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BGI23_11255 ENOG4105BZ4 penicillin-binding protein BGI23_11265 ENOG4105CZM Major Facilitator BGI23_11280 ENOG4105DXD 2-methylcitrate dehydratase BGI23_11285 ENOG4105CR4 methylisocitrate lyase BGI23_11290 ENOG4105C1G acyl-Coa dehydrogenase BGI23_11295 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BGI23_11305 ENOG4105N14 lysine exporter protein LysE YggA BGI23_11310 ENOG4105E39 Enoyl-CoA hydratase BGI23_11325 ENOG4107RFY SbcCD D subunit BGI23_11330 ENOG4105EYH Exonuclease BGI23_11355 ENOG4105FCD Major Facilitator BGI23_11360 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BGI23_11365 ENOG4105E4F Isochorismate synthase BGI23_11370 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BGI23_11375 ENOG4105WQI isochorismatase BGI23_11380 ENOG4105CEY Amp-dependent synthetase and ligase BGI23_11385 ENOG4105WQT MbtH domain protein BGI23_11390 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGI23_11405 ENOG4105K70 DNA-binding protein BGI23_11425 ENOG4105BZG amino acid carrier protein BGI23_11445 ENOG4105FE9 pseudouridine synthase BGI23_11450 ENOG4105C22 threonyL-tRNA synthetase BGI23_11460 ENOG4105C19 ABC transporter BGI23_11470 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BGI23_11500 ENOG4108D32 Methyltransferase BGI23_11525 ENOG41081I9 integral membrane protein BGI23_11540 ENOG4105C5X domain protein BGI23_11550 ENOG4105EYF MMPL domain protein BGI23_11570 ENOG4105WCN acetyltransferase BGI23_11600 ENOG4105C1Q protoporphyrinogen oxidase BGI23_11610 ENOG41068WN BGI23_11620 ENOG4105VEQ Cold shock protein BGI23_11655 ENOG4107V2S Transcriptional regulator BGI23_11660 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BGI23_11675 ENOG4105DND Transcriptional regulator BGI23_11680 ENOG4108RPX mosc domain containing protein BGI23_11695 ENOG4105BZ1 (ABC) transporter BGI23_11700 ENOG4105BZ1 (ABC) transporter BGI23_11715 ENOG4108JCI Transcriptional regulator BGI23_11760 ENOG4108KPJ rna polymerase sigma factor BGI23_11785 ENOG4105F32 YngK protein BGI23_11810 ENOG4105RD7 BadF BadG BcrA BcrD BGI23_11825 ENOG4105C7B Threonine dehydratase BGI23_11870 ENOG4105C1J atp-dependent rna helicase BGI23_11890 ENOG4108RZE Tetr family transcriptional regulator BGI23_11910 ENOG41088CC tellurite resistance protein tehB BGI23_11920 ENOG4108I0C methyltransferase BGI23_11925 ENOG4107RA9 decarboxylase BGI23_11930 ENOG4105K56 Transcriptional regulator BGI23_11970 ENOG4105CIN aminoacyl-histidine dipeptidase BGI23_11980 ENOG4105EQK -acetyltransferase BGI23_11995 ENOG4107RVG penicillin-binding protein BGI23_12000 ENOG4105EMN RNA polymerase sigma factor BGI23_12015 ENOG4107RF6 penicillin-binding protein BGI23_12025 ENOG4105EXC Acyl-transferase BGI23_12075 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BGI23_12080 ENOG4108XG2 Histidine kinase BGI23_12085 ENOG4105WH1 Two component transcriptional regulator luxr family BGI23_12090 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BGI23_12130 ENOG4105C5X domain protein BGI23_12140 ENOG4108VXD carboxy-peptidase BGI23_12165 ENOG4105BZU Histidine kinase BGI23_12190 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BGI23_12240 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BGI23_12250 ENOG4105CEP NADH dehydrogenase BGI23_12270 ENOG4105CJ1 ABC, transporter BGI23_12280 ENOG4107Z3H Transcriptional regulator, TetR family BGI23_12295 ENOG4105C1G acyl-Coa dehydrogenase BGI23_12300 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BGI23_12305 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BGI23_12310 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BGI23_12315 ENOG4105E39 Enoyl-CoA hydratase BGI23_12320 ENOG4107QX3 carboxylase BGI23_12325 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BGI23_12340 ENOG4105DBI uridine monophosphokinase BGI23_12365 ENOG4105T9C HD domain BGI23_12385 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BGI23_12390 ENOG4108RYK Nad-dependent epimerase dehydratase BGI23_12410 ENOG41075H3 AraC family transcriptional regulator BGI23_12470 ENOG41089UC methyltransferase, type 11 BGI23_12485 ENOG4105CUV Homoserine Kinase BGI23_12530 ENOG410900G Protein of unknown function (DUF421) BGI23_12550 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BGI23_12560 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein BGI23_12570 ENOG4105DK7 lysyl-tRNA synthetase BGI23_12640 ENOG4105D6E homoserine dehydrogenase BGI23_12655 ENOG4105ETU transcriptional activator (TenA BGI23_12740 ENOG410667J hydrolase BGI23_12745 ENOG4105BZU Histidine kinase BGI23_12750 ENOG4107RF6 penicillin-binding protein BGI23_12780 ENOG4108HGU Histidine kinase BGI23_12790 ENOG4105RHY Pfam:UPF0157 BGI23_12795 ENOG4105CB2 alcohol dehydrogenase BGI23_12800 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BGI23_12805 ENOG4105CJN penicillin-binding protein BGI23_12810 ENOG4108IG5 Transcriptional regulator BGI23_12815 ENOG4105CHR reductase BGI23_12855 ENOG4108V4B ThiJ pfpI BGI23_12870 ENOG4105F27 Major Facilitator BGI23_12875 ENOG4107Y80 Major Facilitator superfamily BGI23_12890 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BGI23_12915 ENOG4107Y9U Membrane BGI23_12960 ENOG4105FCD Major Facilitator BGI23_12970 ENOG4105E09 nadh pyrophosphatase BGI23_12975 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BGI23_12980 ENOG4108Z4K mutator MutT protein BGI23_13000 ENOG4108XI2 Domain of unknown function (DUF1963) BGI23_13025 ENOG4108NRW Phospholipase, patatin family BGI23_13030 ENOG4105KWG Pfam:DUF1696 BGI23_13065 ENOG4105PKS Excinuclease abc c subunit domain protein BGI23_13105 ENOG4107VFR oxidoreductase BGI23_13130 ENOG4105PAD Hydrolase BGI23_13150 ENOG4108IUM Glycogen debranching enzyme BGI23_13180 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BGI23_13190 ENOG4108Q5Y Membrane BGI23_13245 ENOG4105MSI germination protein ypeb BGI23_13280 ENOG4105CKY Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity) BGI23_13285 ENOG4107Z3H Transcriptional regulator, TetR family BGI23_13315 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BGI23_13335 ENOG4105E98 transcriptional regulator DeoR family BGI23_13355 ENOG4107QKR Dehydrogenase BGI23_13365 ENOG4107RUY (E1 component), alpha subunit BGI23_13375 ENOG4105E1F short-chain dehydrogenase reductase BGI23_13380 ENOG4105RHY Pfam:UPF0157 BGI23_13410 ENOG4107SQ8 Glycine betaine BGI23_13415 ENOG4108IJ7 Glycine betaine BGI23_13440 ENOG4105E66 phosphoriboisomerase A BGI23_13445 ENOG41082BV acetyltransferase BGI23_13450 ENOG4108M1A Chitin-binding protein BGI23_13455 ENOG41087PP glycosyltransferase MGT family BGI23_13480 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BGI23_13485 ENOG4105MSB protein, conserved in bacteria BGI23_13495 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BGI23_13520 ENOG4108Z7F N-acetyltransferase BGI23_13540 ENOG4105EEM helicase BGI23_13560 ENOG4105C9U ATP-dependent DNA helicase RecQ BGI23_13615 ENOG4108M1A Chitin-binding protein BGI23_13635 ENOG4105BZG amino acid carrier protein BGI23_13640 ENOG4105C26 Dehydrogenase BGI23_13645 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BGI23_13650 ENOG4105CTU Proline racemase BGI23_13655 ENOG4105CTU Proline racemase BGI23_13660 ENOG41080HI glycine oxidase BGI23_13670 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BGI23_13705 ENOG4105DCI Phosphohydrolase BGI23_13710 ENOG4107T5V SNARE associated Golgi BGI23_13725 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BGI23_13745 ENOG4105DTQ mandelate racemase muconate lactonizing BGI23_13790 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BGI23_13795 ENOG4105BZU Histidine kinase BGI23_13800 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_13825 ENOG4105CUV Homoserine Kinase BGI23_13835 ENOG4105DPN Oligoendopeptidase f BGI23_13840 ENOG4105DVH amino acid BGI23_13850 ENOG4105EPR degv family BGI23_13915 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BGI23_13920 ENOG4106K7D Major facilitator family transporter BGI23_13945 ENOG4107BMA Transglycosylase associated protein BGI23_13960 ENOG41089UC methyltransferase, type 11 BGI23_13995 ENOG4105CHM Aminotransferase BGI23_14010 ENOG4108ZMI UPF0477 protein BGI23_14025 ENOG4105DVE abc transporter atp-binding protein BGI23_14080 ENOG4105C02 permease BGI23_14095 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) BGI23_14100 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BGI23_14105 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein BGI23_14120 ENOG4105E09 nadh pyrophosphatase BGI23_14140 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BGI23_14185 ENOG4107VC0 DNA alkylation repair enzyme BGI23_14190 ENOG4107VMI polysaccharide deacetylase BGI23_14200 ENOG4108ZCF integral membrane protein BGI23_14205 ENOG4105E0M Sulfatase BGI23_14210 ENOG4105C5H ABC transporter BGI23_14220 ENOG4105EYF MMPL domain protein BGI23_14225 ENOG41082JN Transcriptional regulator BGI23_14265 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BGI23_14300 ENOG41069ER domain protein BGI23_14325 ENOG4105D4B ABC, transporter BGI23_14330 ENOG4105F5R ABC transporter BGI23_14335 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BGI23_14345 ENOG4105DKT Transcriptional regulator BGI23_14350 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) BGI23_14360 ENOG41061GT Aldolase BGI23_14385 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BGI23_14420 ENOG4105II7 pyrroline-5-carboxylate reductase BGI23_14430 ENOG4107258 Transcriptional regulator BGI23_14440 ENOG4105E0Y RtcB Protein BGI23_14445 ENOG4105ECK Fatty Acid Desaturase BGI23_14455 ENOG4105G6Z alkaline phosphatase BGI23_14465 ENOG4105VMP Transcriptional regulator BGI23_14480 ENOG41090T1 Membrane BGI23_14490 ENOG4108WCX response regulator BGI23_14500 ENOG41068WN BGI23_14525 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BGI23_14550 ENOG4105CKK Glycosyl transferase, family 2 BGI23_14570 ENOG4105CKK Glycosyl transferase, family 2 BGI23_14580 ENOG4105C8Y Acetylornithine aminotransferase BGI23_14590 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BGI23_14595 ENOG4108IY8 ABC, transporter BGI23_14610 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BGI23_14655 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BGI23_14665 ENOG4108TVJ Nitroreductase BGI23_14670 ENOG4105FS7 Transcriptional regulator BGI23_14685 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BGI23_14690 ENOG4105WEC Molybdate metabolism regulator BGI23_14700 ENOG4105CMR udp-glucose 4-epimerase BGI23_14705 ENOG4105C19 ABC transporter BGI23_14735 ENOG4108XET gCN5-related N-acetyltransferase BGI23_14750 ENOG4108PCN EamA-like transporter family BGI23_14760 ENOG4107XJU UPF0178 protein BGI23_14795 ENOG410635A Membrane BGI23_14800 ENOG4105KNA -acetyltransferase BGI23_14805 ENOG4108IQI permease BGI23_14815 ENOG4105F1N DNA alkylation repair BGI23_14860 ENOG4107RF6 penicillin-binding protein BGI23_14870 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BGI23_14900 ENOG4105P4J Allophanate hydrolase, subunit 1 BGI23_14905 ENOG4107258 Transcriptional regulator BGI23_14915 ENOG4106N3A copper homeostasis protein cutc BGI23_14920 ENOG4108ZRV stage ii sporulation protein p BGI23_14925 ENOG4108ZHR arsR family transcriptional regulator BGI23_14940 ENOG4105FDT acyl-CoA dehydrogenase BGI23_14955 ENOG4105DWD nucleoside recognition domain protein BGI23_14995 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BGI23_15000 ENOG41087PP glycosyltransferase MGT family BGI23_15065 ENOG4105E2A Dehydrogenase BGI23_15075 ENOG4108IJ0 Aspartate ammonia-lyase BGI23_15080 ENOG4105HDK L-asparaginase BGI23_15085 ENOG4108IMY Transcriptional regulator BGI23_15090 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BGI23_15095 ENOG4105CUB amino acid BGI23_15100 ENOG4105II7 pyrroline-5-carboxylate reductase BGI23_15110 ENOG4108NHD germination protein BGI23_15115 ENOG4108Q8B Spore germination protein BGI23_15135 ENOG4105CSV Glutaminase BGI23_15165 ENOG4107QJQ Mate efflux family protein BGI23_15170 ENOG4107QTZ amino acid BGI23_15180 ENOG4105CGH 5'-nucleotidase BGI23_15185 ENOG4105CH6 catalase BGI23_15220 ENOG4108606 TspO/MBR family BGI23_15225 ENOG4105CVP deoxyribo-dipyrimidine photolyase BGI23_15245 ENOG4105F2M alpha beta hydrolase fold-3 domain protein BGI23_15260 ENOG4108TWJ NADH dehydrogenase subunit 5 BGI23_15265 ENOG4105GPN Uncharacterized conserved protein (DUF2294) BGI23_15275 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BGI23_15295 ENOG4105Z7P Acetyltransferase (GNAT) family BGI23_15305 ENOG4105D6J arsenicaL-resistance protein BGI23_15310 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BGI23_15315 ENOG41085FC arsR family transcriptional regulator BGI23_15330 ENOG4105F7F Chaperone BGI23_15345 ENOG4105CHR reductase BGI23_15350 ENOG4108YXU transcriptional regulator AsnC family BGI23_15390 ENOG4105ED2 Beta-lactamase BGI23_15410 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BGI23_15415 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGI23_15425 ENOG4105IIP Membrane BGI23_15465 ENOG4105K6H D-cysteine desulfhydrase BGI23_15490 ENOG4108NNI Beta-lactamase domain-containing protein BGI23_15495 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BGI23_15505 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BGI23_15520 ENOG4105JQZ Methyltransferase BGI23_15525 ENOG4105D7V transposase BGI23_15555 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BGI23_15575 ENOG4105BZU Histidine kinase BGI23_15590 ENOG4108U05 Transcriptional regulator BGI23_15595 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 BGI23_15605 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BGI23_15630 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BGI23_15640 ENOG4105DUM transcriptional regulator, lysR family BGI23_15645 ENOG4108VP3 Lysine exporter protein (LysE YggA) BGI23_15660 ENOG4108JQ1 Dehydrogenase BGI23_15680 ENOG41082W1 Cupin 2, conserved barrel domain protein BGI23_15690 ENOG410874W AraC family transcriptional regulator BGI23_15715 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BGI23_15765 ENOG4108ISG Major Facilitator BGI23_15780 ENOG4107MII Sugar-specific transcriptional regulator TrmB BGI23_15785 ENOG4105CZM Major Facilitator BGI23_15805 ENOG4105CRW Short chain fatty acid transporter BGI23_15815 ENOG4105DYS nad(p)h dehydrogenase (quinone) BGI23_15850 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BGI23_15885 ENOG4107TXC Transcriptional regulator BGI23_15905 ENOG4108Z66 YbaK ebsC protein BGI23_15920 ENOG4105KVH Transcriptional regulator BGI23_15925 ENOG4108RCM Nitroreductase BGI23_15945 ENOG4108PSK reductase BGI23_15955 ENOG4105CJ1 ABC, transporter BGI23_15985 ENOG4105D7V transposase BGI23_16025 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BGI23_16030 ENOG4105DKQ ROK family BGI23_16035 ENOG4108UW5 maltose o-acetyltransferase BGI23_16040 ENOG4105C31 Tryptophanyl-tRNA synthetase BGI23_16045 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BGI23_16070 ENOG4105DMQ Methyltransferase BGI23_16080 ENOG4105EV4 Multidrug resistance protein mdtH BGI23_16105 ENOG4105C37 (CBS) domain BGI23_16120 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BGI23_16125 ENOG4105FAW cDP-glucose 4,6-dehydratase BGI23_16155 ENOG4105DDN Pentapeptide repeat-containing protein BGI23_16160 ENOG4105XDF Protein of unknown function (DUF1272) BGI23_16165 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BGI23_16170 ENOG4105CMG Carbohydrate kinase BGI23_16175 ENOG4105C6Z Gluconate BGI23_16180 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BGI23_16195 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BGI23_16215 ENOG4105C44 Serine transporter BGI23_16250 ENOG4108TZY GntR Family Transcriptional Regulator BGI23_16255 ENOG4105D9R oxidoreductase BGI23_16290 ENOG4105JAB phenazine biosynthesis protein, phzf family BGI23_16300 ENOG4105CHR reductase BGI23_16315 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BGI23_16320 ENOG4105KVH Transcriptional regulator BGI23_16345 ENOG4108ZJ4 polysaccharide deacetylase BGI23_16390 ENOG4105KAF membrAne BGI23_16435 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BGI23_16445 ENOG4105D7V transposase BGI23_16460 ENOG4107YXZ hydrolase, family 25 BGI23_16495 ENOG4105H3G oxidoreductase BGI23_16540 ENOG4105K7K Transcriptional regulator BGI23_16580 ENOG4108TN2 lmbE family BGI23_16590 ENOG4107R3E Citrate transporter BGI23_16605 ENOG4108MES Periplasmic binding protein BGI23_16610 ENOG4105EHG Permease protein BGI23_16615 ENOG4105DQ5 transport system permease protein BGI23_16620 ENOG4105NX3 Membrane BGI23_16640 ENOG4107V2S Transcriptional regulator BGI23_16660 ENOG4105C98 muts2 protein BGI23_16665 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BGI23_16670 ENOG4105DPN Oligoendopeptidase f BGI23_16675 ENOG4108A04 Beta-lactamase BGI23_16705 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BGI23_16730 ENOG41082BM Transcriptional regulator, arsr family BGI23_16735 ENOG4105CIS alcohol dehydrogenase BGI23_16765 ENOG4105C09 Bile acid BGI23_16770 ENOG4105CQB FAD linked oxidase domain protein BGI23_16810 ENOG4105KT7 mgtC SapB transporter BGI23_16825 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BGI23_16830 ENOG41073R8 VanW family BGI23_16840 ENOG4108R1P BGI23_16855 ENOG4105VEQ Cold shock protein BGI23_16875 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BGI23_16895 ENOG410904N short-chain dehydrogenase reductase BGI23_16905 ENOG4106IQC argininosuccinate lyase BGI23_16920 ENOG4108IA2 Sodium pantothenate symporter BGI23_16930 ENOG4105C26 Dehydrogenase BGI23_16935 ENOG4105CHR reductase BGI23_16945 ENOG4105EWU Squalene--hopene cyclase BGI23_16955 ENOG4105FR1 rard protein BGI23_16960 ENOG410696E Membrane BGI23_16975 ENOG4105D1F ATP-binding protein BGI23_16985 ENOG4108ZAF Molybdopterin BGI23_16990 ENOG4105CVM Molybdenum cofactor synthesis domain protein BGI23_16995 ENOG4105D06 uba thif-type nad fad binding protein BGI23_17000 ENOG4105TMB Formate nitrite transporter BGI23_17010 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BGI23_17015 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BGI23_17025 ENOG4108JB9 formate dehydrogenase BGI23_17035 ENOG4105E1K spore germination protein BGI23_17100 ENOG4107QJT sodium dicarboxylate symporter BGI23_17105 ENOG4108KGH TRANSCRIPTIONal BGI23_17115 ENOG4105EMN RNA polymerase sigma factor BGI23_17130 ENOG4105CIG ABC transporter BGI23_17140 ENOG4105D9R oxidoreductase BGI23_17155 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGI23_17165 ENOG4105K4P CoA-binding domain protein BGI23_17170 ENOG4105C0H protease BGI23_17175 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_17185 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BGI23_17195 ENOG4105W8X HesB YadR YfhF-family protein BGI23_17225 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BGI23_17230 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BGI23_17245 ENOG4108I0Z Aconitate hydratase BGI23_17275 ENOG4105E5W Transporter BGI23_17285 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BGI23_17305 ENOG4107F3J Amp-dependent synthetase and ligase BGI23_17310 ENOG4107ZYJ bioY protein BGI23_17315 ENOG4105CEY Amp-dependent synthetase and ligase BGI23_17330 ENOG4108IMY Transcriptional regulator BGI23_17375 ENOG4107AYK membrAne BGI23_17385 ENOG4105BZU Histidine kinase BGI23_17390 ENOG4105FBA Phospholipase Carboxylesterase BGI23_17395 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BGI23_17400 ENOG4105CK7 Sodium proline symporter BGI23_17405 ENOG4105CBC glutamate synthase BGI23_17410 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BGI23_17420 ENOG4108VJ1 Transcriptional regulator (CarD family BGI23_17425 ENOG4108903 Formimidoylglutamase BGI23_17495 ENOG4107QIV Cytochrome c biogenesis protein BGI23_17505 ENOG4105CH2 amidohydrolase BGI23_17515 ENOG4105CJ1 ABC, transporter BGI23_17525 ENOG4107RSM transcriptional regulator BGI23_17535 ENOG41067MG lrgb family BGI23_17560 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BGI23_17580 ENOG4105BZ1 (ABC) transporter BGI23_17585 ENOG4105BZ1 (ABC) transporter BGI23_17620 ENOG4108HW3 (ABC) transporter BGI23_17625 ENOG4105CGH 5'-nucleotidase BGI23_17635 ENOG4108SVB resolvase BGI23_17655 ENOG4105K7K Transcriptional regulator BGI23_17685 ENOG4105C5F glutamine synthetase BGI23_17690 ENOG4105KV4 Transcriptional regulator BGI23_17695 ENOG4105CXI aluminum resistance protein BGI23_17700 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BGI23_17705 ENOG4105EN6 Membrane BGI23_17710 ENOG4106F1P AAA ATPase, central domain protein BGI23_17740 ENOG41069ER domain protein BGI23_17745 ENOG4105DM4 PTS System BGI23_17750 ENOG4105DE4 1-phosphofructokinase BGI23_17755 ENOG4105E98 transcriptional regulator DeoR family BGI23_17760 ENOG4107QW4 alcohol dehydrogenase BGI23_17765 ENOG4108SJC Membrane BGI23_17780 ENOG4105C85 amino acid BGI23_17795 ENOG4105TMB Formate nitrite transporter BGI23_17800 ENOG4105K70 DNA-binding protein BGI23_17805 ENOG4105C59 p-type ATPase BGI23_17810 ENOG410681U heavy metal transport detoxification protein BGI23_17815 ENOG4105VPX protein, conserved in bacteria BGI23_17825 ENOG4105NIV Esterase BGI23_17830 ENOG4105E0A ABC, transporter BGI23_17855 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BGI23_17860 ENOG4105D03 DNA-3-methyladenine glycosylase II BGI23_17890 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BGI23_17895 ENOG4105BZU Histidine kinase BGI23_17915 ENOG4105C5E polysaccharide biosynthesis protein BGI23_17930 ENOG4107ZY0 Phenazine biosynthesis-like protein BGI23_17940 ENOG41067MG lrgb family BGI23_17970 ENOG4105F0V Cell wall hydrolase BGI23_17975 ENOG4107R6R udp-galactopyranose mutase BGI23_17980 ENOG4105E0M Sulfatase BGI23_17985 ENOG410890F Dynamin family BGI23_17995 ENOG4107QHE Choloylglycine hydrolase BGI23_18010 ENOG4105C4R Atp-dependent dna helicase BGI23_18045 ENOG4105DQU oxidoreductase, subunit beta BGI23_18050 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BGI23_18055 ENOG4108IGT Dipeptidase BGI23_18060 ENOG4105MCT stage V sporulation protein S BGI23_18065 ENOG4105D48 metallophosphoesterase BGI23_18085 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BGI23_18100 ENOG4105XZV Protein of unknown function (DUF3243) BGI23_18105 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BGI23_18125 ENOG4105UIB (ABC) transporter BGI23_18130 ENOG4108JQ9 ABC transporter BGI23_18135 ENOG4105DIH basic membrane BGI23_18140 ENOG4105FDP GntR family transcriptional regulator BGI23_18145 ENOG4107QZI cell division protein FtsK BGI23_18155 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BGI23_18170 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BGI23_18180 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BGI23_18185 ENOG4108S0H Dipicolinic acid synthetase, b subunit BGI23_18190 ENOG4105E35 Dipicolinate synthase subunit A BGI23_18200 ENOG4105C1V Peptidase, M16 BGI23_18220 ENOG4105DTN riboflavin biosynthesis protein ribF BGI23_18235 ENOG4105W7A Protein of unknown function (DUF503) BGI23_18245 ENOG4105VHM ribosomal protein BGI23_18250 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BGI23_18255 ENOG4105CHV Transcription elongation factor NusA BGI23_18265 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BGI23_18275 ENOG4105DZP Membrane-associated zinc metalloprotease BGI23_18280 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BGI23_18285 ENOG4105KNE Phosphatidate cytidylyltransferase BGI23_18330 ENOG4108HE4 integrase family BGI23_18340 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BGI23_18345 ENOG4105C79 DNA protecting protein DprA BGI23_18350 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BGI23_18365 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BGI23_18390 ENOG4105VB6 UPF0109 protein BGI23_18410 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BGI23_18415 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BGI23_18430 ENOG4105CHR reductase BGI23_18435 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BGI23_18450 ENOG4105CB5 ATP-dependent DNA helicase recG BGI23_18455 ENOG4105DP4 dak2 domain fusion protein ylov BGI23_18460 ENOG4108ZAA Alkaline-shock protein BGI23_18475 ENOG4105FJ0 thiamine BGI23_18480 ENOG4105DJV ribulose-phosphate 3-epimerase BGI23_18490 ENOG4105D9P serine threonine protein kinase BGI23_18495 ENOG4108ZF3 Phosphatase BGI23_18505 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BGI23_18515 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BGI23_18520 ENOG4105C25 Primosomal protein n' BGI23_18525 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BGI23_18545 ENOG4105DSJ YicC domain protein BGI23_18555 ENOG4105F23 Fibronectin-binding protein BGI23_18560 ENOG4105DC7 peptidase M24 BGI23_18645 ENOG4105C34 Pseudouridine synthase BGI23_18670 ENOG4105DBK s4 domain protein BGI23_18675 ENOG41067XK integral membrane protein BGI23_18685 ENOG4105DFA alanine racemase domain protein BGI23_18690 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BGI23_18695 ENOG4105WR5 sporulation protein, YlmC YmxH family BGI23_18705 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGI23_18715 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BGI23_18720 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BGI23_18725 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BGI23_18740 ENOG4105CNI cell division protein FtsW BGI23_18755 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BGI23_18760 ENOG4105CJN penicillin-binding protein BGI23_18765 ENOG4105CJN penicillin-binding protein BGI23_18770 ENOG41068DC Essential cell division protein (By similarity) BGI23_18805 ENOG4105KNH Nucleic acid-binding protein BGI23_18815 ENOG41063PX domain protein BGI23_18820 ENOG4105D78 K07001 NTE family protein BGI23_18825 ENOG4105H20 Sporulation integral membrane protein YlbJ BGI23_18835 ENOG4106H78 methyltransferase BGI23_18855 ENOG4107TB6 phosphoglycerate mutase BGI23_18870 ENOG4106UY4 Inherit from COG: Scp-like extracellular BGI23_18920 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BGI23_18925 ENOG4105CNI cell division protein FtsW BGI23_18940 ENOG4108IAB Phoh family BGI23_18960 ENOG4105QA2 BGI23_18965 ENOG4105CI3 gtp-binding protein typa BGI23_18975 ENOG4105ECY inositol monophosphatase BGI23_18995 ENOG4105CXN decarboxylase BGI23_19045 ENOG4105CPP Dehydrogenase, E1 component BGI23_19060 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BGI23_19065 ENOG4108X4Q Hydrolase BGI23_19075 ENOG4105CN5 Metallo-Beta-Lactamase BGI23_19080 ENOG4107ZYR domain protein BGI23_19115 ENOG4108XRC Protein of unknown function (DUF458) BGI23_19125 ENOG4107IN1 Protein of unknown function (DUF1797) BGI23_19140 ENOG4105EPM Diguanylate phosphodiesterase BGI23_19145 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BGI23_19160 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BGI23_19170 ENOG4105UIN BGI23_19230 ENOG4108HGU Histidine kinase BGI23_19240 ENOG4105CHM Aminotransferase BGI23_19245 ENOG4105FKQ transcriptional regulator BGI23_19250 ENOG4105EG2 ABC transporter, permease BGI23_19260 ENOG4107FKK extracellular solute-binding protein family 1 BGI23_19270 ENOG4105CG3 alpha amylase, catalytic region BGI23_19315 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BGI23_19320 ENOG4105CHU acetyl-coa acetyltransferase BGI23_19355 ENOG4105K7K Transcriptional regulator BGI23_19360 ENOG4105DTD Dehydrogenase BGI23_19380 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BGI23_19420 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BGI23_19430 ENOG4106TD9 Diguanylate cyclase BGI23_19450 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BGI23_19465 ENOG4105CID antiterminator BGI23_19475 ENOG4105FDP GntR family transcriptional regulator BGI23_19485 ENOG4105CE4 GlcNAc 6-P deacetylase BGI23_19530 ENOG4107ZE5 PPIases accelerate the folding of proteins BGI23_19535 ENOG4105PTM secreted protein BGI23_19540 ENOG4105J7I hydrolase BGI23_19550 ENOG4105G6R Stage v sporulation protein ae BGI23_19560 ENOG4105CZ3 stage V sporulation protein ad BGI23_19565 ENOG41090VF Stage v sporulation protein ac BGI23_19585 ENOG4105C8J )-transporter BGI23_19590 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGI23_19600 ENOG41082AN stage II sporulation protein BGI23_19605 ENOG4105DZ1 carboxypeptidase BGI23_19610 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BGI23_19615 ENOG4105DVE abc transporter atp-binding protein BGI23_19650 ENOG4105D7N magnesium and cobalt transport protein CorA BGI23_19675 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BGI23_19685 ENOG4105I3K Ferric uptake regulator, Fur family BGI23_19690 ENOG4105MZ9 stage II sporulation protein m BGI23_19710 ENOG4105CPC Aldo Keto reductase BGI23_19720 ENOG4105RHY Pfam:UPF0157 BGI23_19740 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BGI23_19750 ENOG4105ETE Transcriptional regulator (LacI family BGI23_19755 ENOG4108YM7 Gcn5-related n-acetyltransferase BGI23_19775 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BGI23_19780 ENOG4108R6K riboflavin synthase, subunit alpha BGI23_19805 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BGI23_19810 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BGI23_19825 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGI23_19835 ENOG4105DFD Na H antiporter BGI23_19840 ENOG4105CGH 5'-nucleotidase BGI23_19895 ENOG4108IXY short-chain dehydrogenase reductase BGI23_19900 ENOG41069FQ Metallo-beta-lactamase superfamily BGI23_19905 ENOG4105II7 pyrroline-5-carboxylate reductase BGI23_19910 ENOG4105EJQ L-serine dehydratase BGI23_19935 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BGI23_19945 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BGI23_19955 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BGI23_19960 ENOG4105D9U N-acetyltransferase BGI23_19975 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BGI23_19980 ENOG4108QEG Membrane BGI23_19985 ENOG4105CDA abc transporter atp-binding protein BGI23_19990 ENOG4105E5Q amino acid AbC transporter BGI23_19995 ENOG4108HW3 (ABC) transporter BGI23_20005 ENOG4105G7B Protein of unknown function (DUF2992) BGI23_20015 ENOG4108QY0 Membrane BGI23_20030 ENOG4105C7S Dehydrogenase BGI23_20035 ENOG4105CPP Dehydrogenase, E1 component BGI23_20055 ENOG4107RDP Dehydrogenase BGI23_20070 ENOG4108JUB Transcriptional regulator BGI23_20080 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BGI23_20090 ENOG4107QQR Sporulation BGI23_20115 ENOG4108IBT Inherit from COG: transposase BGI23_20120 ENOG4107QQR Sporulation BGI23_20130 ENOG4105S1Z Stage IV sporulation protein B BGI23_20135 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BGI23_20145 ENOG4105DX0 Hemolysin A BGI23_20155 ENOG4105CTB Polyprenyl synthetase BGI23_20180 ENOG4108ZSR alkaline shock protein BGI23_20185 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BGI23_20210 ENOG410644B Stage III sporulation protein af BGI23_20220 ENOG4105KQ4 Stage iii sporulation protein ad BGI23_20225 ENOG4108CQH stage III sporulation protein AC BGI23_20230 ENOG4105KR5 Stage iii sporulation protein BGI23_20235 ENOG4105CD2 stage iii sporulation protein aa BGI23_20260 ENOG4105DC7 peptidase M24 BGI23_20275 ENOG4105CBJ Metal-dependent enzyme BGI23_20285 ENOG4107YBY Hydrolase BGI23_20305 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) BGI23_20310 ENOG4105WZW rhodanese family BGI23_20330 ENOG41080TC multidrug resistance protein BGI23_20370 ENOG4105CJ1 ABC, transporter BGI23_20375 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BGI23_20405 ENOG4105C0D helicase BGI23_20530 ENOG4105C3R Methionine synthase BGI23_20540 ENOG4105C28 cystathionine BGI23_20545 ENOG4105C28 cystathionine BGI23_20565 ENOG4105C5X domain protein BGI23_20575 ENOG4105DKQ ROK family BGI23_20585 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BGI23_20600 ENOG4108UTW Plays a role in the regulation of phosphate uptake BGI23_20605 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BGI23_20610 ENOG4105E2Z phosphate ABC transporter (Permease BGI23_20615 ENOG4105C8U phosphate abc transporter BGI23_20620 ENOG4105PWN phosphate abc transporter BGI23_20625 ENOG4107RF6 penicillin-binding protein BGI23_20635 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BGI23_20660 ENOG4105N80 Ferric uptake regulator, Fur family BGI23_20670 ENOG4105FDK ABC transporter BGI23_20675 ENOG4108JYZ YitT family BGI23_20680 ENOG41069ZM Protein of unknown function (DUF2624) BGI23_20705 ENOG4105EGD dinuclear metal center protein, YbgI family BGI23_20720 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGI23_20725 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BGI23_20760 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BGI23_20765 ENOG4105KG3 cytidine deaminase BGI23_20770 ENOG4107YR5 Diacylglycerol kinase BGI23_20780 ENOG4105CTJ Metal Dependent Phosphohydrolase BGI23_20785 ENOG4105C9A Phoh family BGI23_20800 ENOG41068P3 sporulation protein YqfC BGI23_20805 ENOG4105KTH gatB Yqey BGI23_20815 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BGI23_20820 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BGI23_20850 ENOG4105CSA Coproporphyrinogen iii oxidase BGI23_20855 ENOG4105KVH Transcriptional regulator BGI23_20880 ENOG4105TQK DNA polymerase iii, delta' subunit BGI23_20890 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BGI23_20895 ENOG4108UK2 deaminase BGI23_20900 ENOG4105KQC Competence protein BGI23_20910 ENOG4105DXX methyltransferase BGI23_20920 ENOG4108WF2 Metal Dependent Phosphohydrolase BGI23_20930 ENOG410812S Rna-binding protein BGI23_20940 ENOG4105CQW ribosome biogenesis GTPase YqeH BGI23_20945 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BGI23_20960 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGI23_20990 ENOG4105G6Z alkaline phosphatase BGI23_21000 ENOG4108MUZ hydrolase BGI23_21035 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BGI23_21040 ENOG4105MIR Phenylalanine 4-monooxygenase BGI23_21050 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BGI23_21090 ENOG4105S6R Iron-hydroxamate transporter permease subunit BGI23_21095 ENOG4108HUF Transporter BGI23_21105 ENOG4108EKI Dehydrogenase BGI23_21110 ENOG4105C28 cystathionine BGI23_21140 ENOG4107XRG penicillin-binding protein BGI23_21160 ENOG4105CFP Peptidase U32 BGI23_21165 ENOG4105XYU peptidase (U32 family) BGI23_21170 ENOG4108VQJ O-methyltransferase BGI23_21175 ENOG4105HHA aminodeoxychorismate lyase BGI23_21205 ENOG4105C02 permease BGI23_21220 ENOG41060CR BGI23_21225 ENOG4105C7H Helicase, RecD TraA family BGI23_21240 ENOG4105C3J Cysteine desulfurase BGI23_21250 ENOG4105D1H recombination factor protein RarA BGI23_21255 ENOG4108VCI transcription factor, rsfa family BGI23_21265 ENOG4105CUZ uba thif-type nad fad binding protein BGI23_21290 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BGI23_21300 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BGI23_21305 ENOG41076HS cation diffusion facilitator family transporter BGI23_21310 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BGI23_21320 ENOG4105CKP Polysaccharide Biosynthesis Protein BGI23_21325 ENOG4108QG2 Membrane BGI23_21335 ENOG4105VIE preprotein translocase, subunit YajC BGI23_21350 ENOG41061AI Protein of unknown function (DUF2905) BGI23_21365 ENOG4108HUF Transporter BGI23_21400 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BGI23_21405 ENOG4108IYU L-aspartate oxidase BGI23_21420 ENOG4108RPX mosc domain containing protein BGI23_21425 ENOG4105CQC Prephenate dehydratase BGI23_21440 ENOG4105C19 ABC transporter BGI23_21445 ENOG4105EWM Histidine kinase BGI23_21470 ENOG4105X36 (ribosomal) protein BGI23_21480 ENOG4105C03 ribonuclease BGI23_21495 ENOG4107QMS site-determining protein BGI23_21510 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BGI23_21515 ENOG4105DFF Rod shape-determining protein mreb BGI23_21535 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BGI23_21550 ENOG41068KH stage VI sporulation protein D BGI23_21560 ENOG4105D52 delta-aminolevulinic acid dehydratase BGI23_21585 ENOG4105K56 Transcriptional regulator BGI23_21605 ENOG4108IUQ atp-dependent protease BGI23_21635 ENOG4108QCI YvbH-like oligomerisation region BGI23_21675 ENOG4105M59 Phosphodiesterase, mj0936 family BGI23_21690 ENOG4108XJQ germination protein BGI23_21700 ENOG4108PCX Major Facilitator BGI23_21710 ENOG4105KBX Transcriptional regulator, TetR family BGI23_21725 ENOG4105PFC Transcriptional regulator BGI23_21740 ENOG4105DZC cytosine deaminase BGI23_21745 ENOG41067S9 phage shock protein C, PspC BGI23_21750 ENOG4108JCI Transcriptional regulator BGI23_21760 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BGI23_21765 ENOG4108Z40 Transcriptional regulator BGI23_21770 ENOG4105RHA ABC transporter, permease BGI23_21775 ENOG4108IUX (ABC) transporter BGI23_21780 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BGI23_21785 ENOG4105ER2 Ompa motb domain protein BGI23_21790 ENOG4105E14 MotA TolQ exbB proton channel BGI23_21795 ENOG4108VXD carboxy-peptidase BGI23_21805 ENOG4105E33 succinate dehydrogenase BGI23_21815 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BGI23_21830 ENOG4105K63 Thioredoxin BGI23_21835 ENOG4105C10 Electron transfer flavoprotein BGI23_21840 ENOG4105BZJ Electron transfer flavoprotein BGI23_21845 ENOG41060WC Enoyl-CoA hydratase BGI23_21850 ENOG4107Z3H Transcriptional regulator, TetR family BGI23_21855 ENOG4105CEY Amp-dependent synthetase and ligase BGI23_21910 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGI23_21925 ENOG4105DR4 Methyltransferase BGI23_21940 ENOG4105KFN sortase, SrtB family BGI23_21945 ENOG4105E0A ABC, transporter BGI23_21960 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BGI23_21965 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BGI23_21975 ENOG4105FE9 pseudouridine synthase BGI23_21990 ENOG4105DCG PHP domain protein BGI23_22040 ENOG4108RWN rrna methyltransferase BGI23_22080 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGI23_22085 ENOG4105CW7 secretion protein, HlyD family BGI23_22090 ENOG4108JGH Tetr family transcriptional regulator BGI23_22095 ENOG4105CN9 Peptidase m42 family protein BGI23_22115 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BGI23_22120 ENOG4105C22 threonyL-tRNA synthetase BGI23_22125 ENOG4108TDW sporulation protein YtxC BGI23_22145 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BGI23_22150 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BGI23_22170 ENOG4105C2M dna polymerase I BGI23_22175 ENOG4105BZU Histidine kinase BGI23_22180 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGI23_22200 ENOG4108HMX isocitrate dehydrogenase (NADP) BGI23_22205 ENOG4105BZN citrate synthase BGI23_22220 ENOG4108REF Sporulation integral membrane protein ytvi BGI23_22225 ENOG4105FS0 cytoplasmic membrane protein BGI23_22250 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BGI23_22255 ENOG4105C6K Malic enzyme BGI23_22260 ENOG4105C0B DNA polymerase III (alpha subunit) BGI23_22265 ENOG4105VV2 BGI23_22275 ENOG4105SFS phosphoesterase RecJ domain protein BGI23_22315 ENOG4105DC7 peptidase M24 BGI23_22350 ENOG41082W1 Cupin 2, conserved barrel domain protein BGI23_22370 ENOG4107YZX Universal stress protein BGI23_22405 ENOG4108JYZ YitT family BGI23_22435 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BGI23_22440 ENOG4105KBJ sporulation protein ytfj BGI23_22455 ENOG4105EFZ amidohydrolase BGI23_22465 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BGI23_22490 ENOG4105C5Q Transcriptional regulator BGI23_22500 ENOG4105U5Y Transcriptional regulator BGI23_22510 ENOG4105C28 cystathionine BGI23_22545 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BGI23_22555 ENOG4105EMN RNA polymerase sigma factor BGI23_22570 ENOG4105F1V Acetoin utilization protein BGI23_22575 ENOG4105W87 Cbs domain BGI23_22580 ENOG4105DGU Histone deacetylase BGI23_22585 ENOG4106HB6 Alpha beta hydrolase BGI23_22595 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGI23_22605 ENOG4107SNB ankyrin repeat protein YahD BGI23_22610 ENOG4105EP9 oxidoreductase BGI23_22640 ENOG4105ETE Transcriptional regulator (LacI family BGI23_22665 ENOG4105C88 aminopeptidase BGI23_22695 ENOG4108IPJ Membrane BGI23_22705 ENOG4105K7K Transcriptional regulator BGI23_22740 ENOG4108VDD TRNA binding domain protein BGI23_22770 ENOG4105C8F Beta-lactamase domain protein BGI23_22785 ENOG4108V15 phosphotransferase enzyme family BGI23_22790 ENOG4108IUM Glycogen debranching enzyme BGI23_22805 ENOG4107QSE Dipeptidase BGI23_22810 ENOG4105YW5 deoR family transcriptional regulator BGI23_22825 ENOG4105CBX hi0933 family BGI23_22860 ENOG4108VJ1 Transcriptional regulator (CarD family BGI23_22865 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BGI23_22885 ENOG4108ZAF Molybdopterin BGI23_22890 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BGI23_22895 ENOG4105CVM Molybdenum cofactor synthesis domain protein BGI23_22905 ENOG4105D06 uba thif-type nad fad binding protein BGI23_22910 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BGI23_22930 ENOG41085GJ domain protein BGI23_22940 ENOG4105DWV Homoserine O-trans-acetylase BGI23_22950 ENOG4108B31 Spore germination protein BGI23_22975 ENOG4105C8T Leucyl-tRNA synthetase BGI23_22980 ENOG410605W Major Facilitator BGI23_22985 ENOG4107S91 Sodium hydrogen exchanger BGI23_22990 ENOG4105NCW Trka-c domain protein BGI23_23005 ENOG4105C19 ABC transporter BGI23_23025 ENOG4105N5T Radical SAM Protein BGI23_23035 ENOG4105CIG ABC transporter BGI23_23070 ENOG4105E8V Alpha Beta Hydrolase Fold protein BGI23_23075 ENOG4108Z0R Transferase BGI23_23080 ENOG4105YVM Phosphoesterase, PA-phosphatase related BGI23_23085 ENOG4105BZF Glycosyl transferase (Group 1 BGI23_23095 ENOG4105EPU Molybdenum cofactor synthesis domain protein BGI23_23110 ENOG4108MK9 spermidine N(1)-acetyltransferase BGI23_23155 ENOG4105E98 transcriptional regulator DeoR family BGI23_23165 ENOG4105BZU Histidine kinase BGI23_23170 ENOG4105BZU Histidine kinase BGI23_23175 ENOG4107S9D Alpha beta hydrolase BGI23_23180 ENOG4107T7U Sulfatase BGI23_23200 ENOG4105D2X ABC transporter substrate-binding protein BGI23_23210 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BGI23_23270 ENOG4108V2W Carbonate dehydratase BGI23_23275 ENOG4105C4M (Ubiquinol oxidase) subunit I BGI23_23280 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BGI23_23325 ENOG41087YS Phage shock protein A BGI23_23340 ENOG4108IBT Inherit from COG: transposase BGI23_23370 ENOG4105BZU Histidine kinase BGI23_23375 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_23400 ENOG4108UGV hypoxanthine phosphoribosyltransferase BGI23_23405 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BGI23_23430 ENOG4107ZTW SNARE associated Golgi BGI23_23435 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BGI23_23445 ENOG4105C19 ABC transporter BGI23_23450 ENOG41086D8 Transcriptional regulator BGI23_23465 ENOG41082BM Transcriptional regulator, arsr family BGI23_23515 ENOG4105C6Z Gluconate BGI23_23520 ENOG4105FDP GntR family transcriptional regulator BGI23_23540 ENOG41069H0 dihydroorotase EC 3.5.2.3 BGI23_23560 ENOG4105DTQ mandelate racemase muconate lactonizing BGI23_23575 ENOG4108IPT Naphthoate synthase BGI23_23580 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BGI23_23590 ENOG4105E4F Isochorismate synthase BGI23_23595 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BGI23_23605 ENOG4105VEQ Cold shock protein BGI23_23655 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BGI23_23755 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BGI23_23790 ENOG4105KT7 mgtC SapB transporter BGI23_23795 ENOG4107PBV potassium channel BGI23_23815 ENOG4105WG9 Conserved Protein BGI23_23825 ENOG4105CHM Aminotransferase BGI23_23830 ENOG4108ZB6 transcriptional regulator AsnC family BGI23_23835 ENOG4105C5I Dehydrogenase BGI23_23840 ENOG4108MUZ hydrolase BGI23_23850 ENOG4105C87 Aminotransferase class I and II BGI23_23865 ENOG4105Y38 Kinase-associated protein B BGI23_23875 ENOG4107R3E Citrate transporter BGI23_23890 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) BGI23_23895 ENOG4105KA0 thioesterase Superfamily protein BGI23_23910 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BGI23_23930 ENOG41069ER domain protein BGI23_23945 ENOG4105CEP NADH dehydrogenase BGI23_23970 ENOG4105EWC Purine nucleoside phosphorylase BGI23_23985 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BGI23_24010 ENOG4108JJA ABC, transporter BGI23_24015 ENOG4105C4B ABC transporter, permease BGI23_24020 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BGI23_24045 ENOG41083MR nifu domain-containing protein BGI23_24060 ENOG4108W5N phosphatidylglycerophosphatase a BGI23_24075 ENOG4105DYS nad(p)h dehydrogenase (quinone) BGI23_24080 ENOG4105D4U had-superfamily hydrolase, subfamily iia BGI23_24095 ENOG4105CBT Fructose-1,6-bisphosphatase BGI23_24115 ENOG4105MMD transcriptional regulator BGI23_24120 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BGI23_24125 ENOG4107TXC Transcriptional regulator BGI23_24130 ENOG41090T1 Membrane BGI23_24155 ENOG4105FAA peptidase M23 BGI23_24165 ENOG4105KZD Domain of unknown function (DUF1805) BGI23_24170 ENOG4107R8B 5'-nucleotidase BGI23_24175 ENOG4105D5G Transposase BGI23_24185 ENOG4105DIW FeS assembly protein SUFB BGI23_24190 ENOG4108UNV SUF system FeS assembly protein, NifU family BGI23_24195 ENOG4105C9B Cysteine desulfurase BGI23_24200 ENOG4105JRK feS assembly protein SufD BGI23_24205 ENOG4105C3K feS assembly ATPase SufC BGI23_24210 ENOG4105D01 (LipO)protein BGI23_24215 ENOG4105D01 (LipO)protein BGI23_24220 ENOG4108UMI ABC transporter, permease BGI23_24250 ENOG41080E8 Transcriptional regulator, Spx MgsR family BGI23_24305 ENOG4108W8B Beta-lactamase domain protein BGI23_24310 ENOG4105C1G acyl-Coa dehydrogenase BGI23_24320 ENOG4105CHU acetyl-coa acetyltransferase BGI23_24335 ENOG4105DZ1 carboxypeptidase BGI23_24355 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BGI23_24375 ENOG4108SUT Major Facilitator Superfamily BGI23_24380 ENOG4107R7I amino acid BGI23_24390 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BGI23_24400 ENOG4107AYK membrAne BGI23_24440 ENOG4107ZTW SNARE associated Golgi BGI23_24450 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BGI23_24455 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_24460 ENOG4105BZU Histidine kinase BGI23_24485 ENOG4105C8Q Methyl-accepting chemotaxis BGI23_24490 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BGI23_24495 ENOG4105VG1 fes assembly suf system protein BGI23_24500 ENOG4105D4Y metalloprotease BGI23_24520 ENOG4107S91 Sodium hydrogen exchanger BGI23_24525 ENOG4105NCW Trka-c domain protein BGI23_24540 ENOG4108RMU ferritin dps family protein BGI23_24555 ENOG4108URH decarboxylase BGI23_24575 ENOG4105D9N nucleoside BGI23_24580 ENOG4105D9N nucleoside BGI23_24595 ENOG4108RYK Nad-dependent epimerase dehydratase BGI23_24610 ENOG4105CV8 reductase BGI23_24615 ENOG4105F27 Major Facilitator BGI23_24620 ENOG4105KVH Transcriptional regulator BGI23_24635 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BGI23_24650 ENOG4105C8Q Methyl-accepting chemotaxis BGI23_24660 ENOG4105WMR Protein CrcB homolog BGI23_24690 ENOG4105C5H ABC transporter BGI23_24695 ENOG4108MK9 spermidine N(1)-acetyltransferase BGI23_24700 ENOG4108VY7 phosphate-starvation-inducible protein PsiE BGI23_24710 ENOG4108IPW abc transporter atp-binding protein BGI23_24715 ENOG4105CM4 permease protein BGI23_24740 ENOG4108SGK Tetr family transcriptional regulator BGI23_24745 ENOG41067SE Tetr family transcriptional regulator BGI23_24775 ENOG4105DZR Type I site-specific deoxyribonuclease BGI23_24830 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BGI23_24840 ENOG4105XZU Preprotein translocase, subunit SecG BGI23_24845 ENOG41067MG lrgb family BGI23_24895 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGI23_24985 ENOG41090VF Stage v sporulation protein ac BGI23_24990 ENOG4105CZ3 stage V sporulation protein ad BGI23_25005 ENOG4108QY0 Membrane BGI23_25010 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BGI23_25015 ENOG4105KRI phosphocarrier protein (HPr BGI23_25025 ENOG4105CHW UPF0052 protein BGI23_25035 ENOG4108Z4K mutator MutT protein BGI23_25045 ENOG4105C3M thioredoxin reductase BGI23_25055 ENOG4108S4C acetyltransferase BGI23_25075 ENOG41086DT Membrane protein of unknown function BGI23_25085 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BGI23_25105 ENOG4107TXC Transcriptional regulator BGI23_25140 ENOG4105DUM transcriptional regulator, lysR family BGI23_25150 ENOG4108WS4 fmn reductase BGI23_25165 ENOG4105BZ1 (ABC) transporter BGI23_25175 ENOG4105CN1 protease BGI23_25180 ENOG4105CRP Part of the ABC transporter FtsEX involved in BGI23_25185 ENOG4105CAK Cell division ATP-binding protein ftsE BGI23_25195 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BGI23_25210 ENOG4108RDQ ABC transporter BGI23_25240 ENOG4105MS2 ribosomal subunit Interface protein BGI23_25245 ENOG4105VEQ Cold shock protein BGI23_25250 ENOG41081UC Inherit from COG: Competence protein BGI23_25265 ENOG4105KVH Transcriptional regulator BGI23_25280 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BGI23_25285 ENOG4108KGH TRANSCRIPTIONal BGI23_25290 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BGI23_25295 ENOG4105C6Y Udp-glucose 6-dehydrogenase BGI23_25300 ENOG4105ESV Glycosyl transferase, family 4 BGI23_25310 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGI23_25330 ENOG4105F8D glycoside hydrolase family 4 BGI23_25335 ENOG4105VCP PTS System BGI23_25340 ENOG4105CK1 PTS System BGI23_25350 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BGI23_25370 ENOG4105VCP PTS System BGI23_25380 ENOG4105VZJ PTS System BGI23_25395 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase BGI23_25400 ENOG4105ECB domain protein BGI23_25405 ENOG4107RSM transcriptional regulator BGI23_25445 ENOG4105DAA L-lactate BGI23_25455 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BGI23_25465 ENOG4105E0M Sulfatase BGI23_25490 ENOG4107R8N Glycosyl transferase, family 2 BGI23_25500 ENOG4105C94 Transporter BGI23_25505 ENOG41069ER domain protein BGI23_25530 ENOG4105KBK Zinc finger, swim domain protein BGI23_25535 ENOG4105C0D helicase BGI23_25565 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGI23_25575 ENOG4107RBB ABC transporter, permease BGI23_25580 ENOG4105C19 ABC transporter BGI23_25600 ENOG4105CXY transporter BGI23_25615 ENOG4105BZU Histidine kinase BGI23_25620 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_25625 ENOG4105CMR udp-glucose 4-epimerase BGI23_25650 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BGI23_25660 ENOG4105EY8 ABC transporter BGI23_25705 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BGI23_25710 ENOG4107BJW polysaccharide deacetylase BGI23_25720 ENOG4105FRN stage II sporulation protein BGI23_25735 ENOG4105DY9 regulatoR BGI23_25755 ENOG4106778 Protein of unknown function (DUF1146) BGI23_25760 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BGI23_25765 ENOG4105C8S subunit m BGI23_25770 ENOG4105D65 subunit l BGI23_25800 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BGI23_25815 ENOG4105BZU Histidine kinase BGI23_25855 ENOG4107ZFM Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity) BGI23_25865 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BGI23_25870 ENOG41062M3 atp synthase BGI23_25900 ENOG4108YZG isomerase BGI23_25915 ENOG4108VGI doxx family BGI23_25920 ENOG4107XC4 flavin reductase domain protein, FMN-binding BGI23_25940 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BGI23_25950 ENOG4108ZXQ stage ii sporulation protein r BGI23_25955 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BGI23_25960 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BGI23_25975 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BGI23_25980 ENOG4105CBT Fructose-1,6-bisphosphatase BGI23_25985 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BGI23_26020 ENOG4105C1G acyl-Coa dehydrogenase BGI23_26025 ENOG4105C1G acyl-Coa dehydrogenase BGI23_26030 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BGI23_26040 ENOG4105DF6 Fe-S oxidoreductase BGI23_26055 ENOG4105BZU Histidine kinase BGI23_26080 ENOG4105BZU Histidine kinase BGI23_26085 ENOG4105KCT ABC transporter BGI23_26090 ENOG4108M15 ABC transporter BGI23_26095 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BGI23_26105 ENOG4105IIU Aminopeptidase BGI23_26125 ENOG4105EMN RNA polymerase sigma factor BGI23_26135 ENOG410684U Domain of unknown function (DUF1934) BGI23_26155 ENOG4105CYW agmatinase BGI23_26165 ENOG4105DXB Major Facilitator superfamily BGI23_26170 ENOG4107SWG transcriptional regulator MERR family BGI23_26175 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BGI23_26180 ENOG4105BZ4 penicillin-binding protein BGI23_26185 ENOG4108XFG YwhD family BGI23_26190 ENOG4108Z4T Peptidase M50 BGI23_26195 ENOG41069HH 4-oxalocrotonate tautomerase BGI23_26200 ENOG4105DCI Phosphohydrolase BGI23_26205 ENOG4108MES Periplasmic binding protein BGI23_26210 ENOG4105E0A ABC, transporter BGI23_26215 ENOG4105EHG Permease protein BGI23_26220 ENOG4105DQ5 transport system permease protein BGI23_26230 ENOG4108VCI transcription factor, rsfa family BGI23_26245 ENOG4108IJ2 phosphate acetyltransferase BGI23_26260 ENOG4108VKI Cell wall hydrolase BGI23_26280 ENOG4107SVH Potassium channel protein BGI23_26290 ENOG410667J hydrolase BGI23_26295 ENOG4105VCH membrane BGI23_26305 ENOG4108TU7 Inherit from COG: (ABC) transporter BGI23_26310 ENOG4105CJ1 ABC, transporter BGI23_26315 ENOG41090WU lipolytic protein G-D-S-L family BGI23_26330 ENOG4105D6E homoserine dehydrogenase BGI23_26355 ENOG4108Y4K DNA-binding transcriptional activator BGI23_26365 ENOG4105WH1 Two component transcriptional regulator luxr family BGI23_26370 ENOG4105BZU Histidine kinase BGI23_26375 ENOG4105DWF phosphomethylpyrimidine kinase BGI23_26380 ENOG4105BZU Histidine kinase BGI23_26385 ENOG4105VCD cytoplasmic protein BGI23_26390 ENOG4105D22 carbon starvation protein BGI23_26395 ENOG4105DY9 regulatoR BGI23_26400 ENOG41079KZ Major Facilitator Superfamily BGI23_26410 ENOG4105CG5 Glycosyl transferase (Group 1 BGI23_26420 ENOG4105EN6 Membrane BGI23_26425 ENOG4106YBV Methyl-accepting chemotaxis BGI23_26435 ENOG4108S4H thioesterase Superfamily protein BGI23_26440 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BGI23_26450 ENOG4105K64 Glycosyl transferase, family 2 BGI23_26465 ENOG4105C5H ABC transporter BGI23_26480 ENOG4105CKK Glycosyl transferase, family 2 BGI23_26485 ENOG41067SE Tetr family transcriptional regulator BGI23_26495 ENOG4105E0X reductase BGI23_26500 ENOG4106F5Q Membrane BGI23_26515 ENOG4105DY9 regulatoR BGI23_26520 ENOG4108HRK Histidine kinase BGI23_26525 ENOG4107RGD Major Facilitator superfamily BGI23_26540 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BGI23_26550 ENOG4105IW1 AmiS UreI transporter BGI23_26585 ENOG4105CMR udp-glucose 4-epimerase BGI23_26590 ENOG4108UT2 hemolysin iii BGI23_26600 ENOG4105C1J atp-dependent rna helicase BGI23_26610 ENOG4105DPN Oligoendopeptidase f BGI23_26630 ENOG4105C0H protease BGI23_26635 ENOG4105Q2H domain protein BGI23_26650 ENOG4105BZU Histidine kinase BGI23_26655 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGI23_26685 ENOG4105CDU Replicative dna helicase BGI23_26695 ENOG4105BZR domain protein BGI23_26700 ENOG4108XMW Membrane BGI23_26710 ENOG4108UUM single-stranded DNA-binding protein BGI23_26720 ENOG4105C3G gtp-binding protein BGI23_26725 ENOG4105VDK protein, conserved in bacteria BGI23_26730 ENOG4105D8X mechanosensitive ion channel BGI23_26735 ENOG4108ZDA Sporulation protein YyaC BGI23_26740 ENOG4105FA0 parb-like partition protein BGI23_26745 ENOG4107QJE Chromosome Partitioning Protein BGI23_26775 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BGI23_26800 ENOG41067QW Transcriptional regulator