locus-tag	class	description
DN399_00010	COG0592	DNA-directed DNA polymerase activity
DN399_00015	COG2501	S4 domain
DN399_00025	COG0187	DNA topoisomerase II activity
DN399_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN399_00065	COG0517	IMP dehydrogenase activity
DN399_00065	COG0516	GMP reductase activity
DN399_00070	COG1686	Belongs to the peptidase S11 family
DN399_00100	COG1428	Deoxynucleoside kinase
DN399_00105	COG1428	Deoxynucleoside kinase
DN399_00110	COG1335	isochorismatase
DN399_00120	COG0590	tRNA wobble adenosine to inosine editing
DN399_00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DN399_00185	COG1982	Orn Lys Arg decarboxylase major
DN399_00195	COG0470	DNA polymerase III
DN399_00200	COG1774	PSP1 C-terminal conserved region
DN399_00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DN399_00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DN399_00225	COG2002	toxin-antitoxin pair type II binding
DN399_00235	COG0084	hydrolase, TatD family'
DN399_00255	COG4466	Protein conserved in bacteria
DN399_00270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DN399_00275	COG0251	oxidation-reduction process
DN399_00290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DN399_00305	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DN399_00310	COG2002	toxin-antitoxin pair type II binding
DN399_00315	COG2244	polysaccharide biosynthetic process
DN399_00320	COG3956	TIGRFAM MazG family protein
DN399_00325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DN399_00345	COG1098	S1 RNA binding domain
DN399_00360	COG2208	phosphoserine phosphatase activity
DN399_00375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DN399_00390	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN399_00395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DN399_00400	COG0512	Glutamine amidotransferase of anthranilate synthase
DN399_00405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN399_00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DN399_00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DN399_00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DN399_00425	COG1396	sequence-specific DNA binding
DN399_00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN399_00520	COG3880	PFAM UvrB UvrC protein
DN399_00530	COG0542	response to heat
DN399_00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DN399_00545	COG4956	integral membrane protein (PIN domain superfamily)
DN399_00565	COG1045	serine acetyltransferase
DN399_00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN399_00585	COG3688	RNA-binding protein containing a PIN domain
DN399_00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DN399_00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN399_00605	COG0250	Participates in transcription elongation, termination and antitermination
DN399_00630	COG2813	Specifically methylates the guanine in position
DN399_00645	COG1358	cellular component organization or biogenesis
DN399_00755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DN399_00780	COG0201	protein transport
DN399_00790	COG0024	Methionine aminopeptidase
DN399_00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DN399_00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DN399_00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN399_00865	COG0489	protein tyrosine kinase activity
DN399_00875	COG2194	sulfuric ester hydrolase activity
DN399_00880	COG0726	polysaccharide deacetylase
DN399_00960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DN399_00965	COG4856	YbbR-like protein
DN399_01005	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_01010	COG2011	ABC-type metal ion transport system permease component
DN399_01015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DN399_01020	COG1464	Belongs to the NlpA lipoprotein family
DN399_01025	COG0604	alcohol dehydrogenase
DN399_01035	COG0277	FAD linked oxidase domain protein
DN399_01040	COG2271	Major facilitator Superfamily
DN399_01050	COG2814	Major facilitator Superfamily
DN399_01065	COG0601	transmembrane transport
DN399_01070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN399_01075	COG0444	Belongs to the ABC transporter superfamily
DN399_01080	COG4608	Belongs to the ABC transporter superfamily
DN399_01085	COG4166	transmembrane transport
DN399_01095	COG2207	Transcriptional regulator
DN399_01110	COG4166	transmembrane transport
DN399_01115	COG4166	transmembrane transport
DN399_01120	COG0656	L-ascorbic acid biosynthetic process
DN399_01135	COG4149	molybdate abc transporter
DN399_01140	COG0725	ABC transporter, periplasmic molybdate-binding protein
DN399_01145	COG1910	domain protein
DN399_01160	COG0697	spore germination
DN399_01175	COG0204	Acyl-transferase
DN399_01185	COG1609	Transcriptional regulator
DN399_01195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_01210	COG5298	Protein conserved in bacteria
DN399_01230	COG0488	(ABC) transporter
DN399_01245	COG0747	negative chemotaxis
DN399_01250	COG0601	transmembrane transport
DN399_01260	COG0444	Belongs to the ABC transporter superfamily
DN399_01265	COG4608	Belongs to the ABC transporter superfamily
DN399_01270	COG0561	phosphatase activity
DN399_01300	COG3185	4-Hydroxyphenylpyruvate dioxygenase
DN399_01305	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN399_01315	COG0531	amino acid
DN399_01320	COG2814	Major facilitator Superfamily
DN399_01330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DN399_01340	COG4294	response to UV
DN399_01345	COG0705	Rhomboid family
DN399_01355	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DN399_01360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN399_01365	COG0864	Transcriptional regulator
DN399_01370	COG2337	Toxic component of a toxin-antitoxin (TA) module
DN399_01375	COG2183	response to ionizing radiation
DN399_01475	COG0802	atpase or kinase
DN399_01480	COG1214	PFAM Peptidase M22, glycoprotease
DN399_01485	COG0456	acetyltransferase
DN399_01495	COG0488	(ABC) transporter
DN399_01510	COG1266	CAAX protease self-immunity
DN399_01530	COG2252	PERMEase
DN399_01540	COG5002	protein histidine kinase activity
DN399_01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN399_01615	COG2205	protein histidine kinase activity
DN399_01620	COG0745	RESPONSE REGULATOR receiver
DN399_01650	COG2226	methyltransferase
DN399_01660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN399_01670	COG0463	Glycosyl transferase, family 2
DN399_01670	COG1216	Glycosyl transferase, family 2
DN399_01690	COG0697	spore germination
DN399_01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DN399_01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DN399_01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DN399_01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DN399_01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DN399_01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DN399_01775	COG0151	Belongs to the GarS family
DN399_01805	COG0210	DNA helicase
DN399_01815	COG4851	CamS sex pheromone cAM373 precursor
DN399_01830	COG1335	isochorismatase
DN399_01840	COG2011	ABC-type metal ion transport system permease component
DN399_01845	COG1464	Belongs to the NlpA lipoprotein family
DN399_01860	COG0003	Pfam Anion-transporting ATPase
DN399_01865	COG1846	Transcriptional regulator
DN399_01870	COG4682	membrane
DN399_01890	COG1597	lipid kinase activity
DN399_01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DN399_01910	COG1012	belongs to the aldehyde dehydrogenase family
DN399_01915	COG2076	Multidrug Resistance protein
DN399_01925	COG2309	aminopeptidase activity
DN399_01940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN399_01950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN399_01955	COG4807	Protein conserved in bacteria
DN399_01990	COG1473	amidohydrolase
DN399_02005	COG0450	alkyl hydroperoxide reductase
DN399_02010	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
DN399_02020	COG0235	Class ii aldolase
DN399_02025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_02030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_02035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN399_02060	COG0166	Belongs to the GPI family
DN399_02085	COG5002	protein histidine kinase activity
DN399_02105	COG3541	Predicted nucleotidyltransferase
DN399_02110	COG2814	Major facilitator Superfamily
DN399_02115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN399_02115	COG0723	plastoquinol--plastocyanin reductase activity
DN399_02125	COG0765	amino acid transport
DN399_02130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN399_02140	COG0840	transmembrane signaling receptor activity
DN399_02165	COG0549	Belongs to the carbamate kinase family
DN399_02170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN399_02180	COG0277	FAD linked oxidase domain protein
DN399_02185	COG0366	Alpha amylase catalytic
DN399_02190	COG1263	PTS System
DN399_02190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN399_02190	COG2190	(PTS) system
DN399_02220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DN399_02240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN399_02245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN399_02250	COG1116	anion transmembrane transporter activity
DN399_02300	COG2270	Major facilitator Superfamily
DN399_02330	COG2310	stress, protein
DN399_02335	COG2310	stress, protein
DN399_02340	COG2310	stress, protein
DN399_02345	COG0861	Integral membrane protein TerC family
DN399_02355	COG3853	Toxic anion resistance protein (TelA)
DN399_02370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DN399_02380	COG1295	ribonuclease BN
DN399_02385	COG2217	Heavy metal translocating P-type atpase
DN399_02390	COG0697	spore germination
DN399_02410	COG0586	Pfam SNARE associated Golgi protein
DN399_02425	COG3871	stress protein (general stress protein 26)
DN399_02430	COG0387	Pfam Sodium calcium exchanger
DN399_02440	COG0535	radical SAM domain protein
DN399_02460	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DN399_02465	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DN399_02480	COG3829	transcription factor binding
DN399_02490	COG0833	amino acid
DN399_02495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN399_02525	COG1263	PTS System
DN399_02525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN399_02530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN399_02545	COG0463	Glycosyl transferase, family 2
DN399_02555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DN399_02555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN399_02575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DN399_02595	COG1228	amidohydrolase
DN399_02600	COG1090	epimerase
DN399_02630	COG1988	membrane-bound metal-dependent
DN399_02635	COG1194	a g-specific adenine glycosylase
DN399_02660	COG1132	(ABC) transporter
DN399_02665	COG4129	membrane
DN399_02670	COG0069	glutamate synthase activity
DN399_02670	COG0067	glutamate synthase
DN399_02670	COG0070	glutamate synthase
DN399_02680	COG4555	ABC transporter
DN399_02700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN399_02705	COG0735	belongs to the Fur family
DN399_02825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DN399_02850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DN399_02860	COG2766	serine protein kinase
DN399_02880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN399_02890	COG1585	Membrane protein implicated in regulation of membrane protease activity
DN399_02895	COG2268	Band 7 protein
DN399_02905	COG3290	protein histidine kinase activity
DN399_02910	COG4565	transcriptional regulatory protein
DN399_02915	COG2851	Citrate transporter
DN399_02940	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DN399_02945	COG3842	ATPase activity
DN399_02950	COG1175	transmembrane transport
DN399_02955	COG0395	ABC-type sugar transport system, permease component
DN399_02965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DN399_02970	COG0745	RESPONSE REGULATOR receiver
DN399_02975	COG3850	Histidine kinase
DN399_02975	COG5002	protein histidine kinase activity
DN399_02985	COG4990	cell redox homeostasis
DN399_02995	COG3290	protein histidine kinase activity
DN399_03000	COG4565	transcriptional regulatory protein
DN399_03005	COG3493	citrate carrier protein
DN399_03010	COG0281	malic enzyme
DN399_03020	COG0697	spore germination
DN399_03025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_03035	COG5002	protein histidine kinase activity
DN399_03045	COG0456	acetyltransferase
DN399_03045	COG0454	-acetyltransferase
DN399_03050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DN399_03055	COG3383	formate dehydrogenase (NAD+) activity
DN399_03060	COG2427	Protein of unknown function (DUF1641)
DN399_03075	COG0531	amino acid
DN399_03085	COG0640	Transcriptional regulator
DN399_03090	COG2217	Heavy metal translocating P-type atpase
DN399_03095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DN399_03105	COG3227	Zinc metalloprotease (Elastase)
DN399_03125	COG2720	vancomycin resistance protein
DN399_03130	COG1316	TRANSCRIPTIONal
DN399_03135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN399_03140	COG0346	lactoylglutathione lyase activity
DN399_03145	COG1253	flavin adenine dinucleotide binding
DN399_03150	COG1027	Aspartate ammonia-lyase
DN399_03155	COG1620	l-lactate permease
DN399_03170	COG3104	oligopeptide transport
DN399_03175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN399_03180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_03185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_03195	COG2226	methyltransferase
DN399_03205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN399_03215	COG4548	von Willebrand factor, type A
DN399_03220	COG0714	Associated with various cellular activities
DN399_03240	COG0531	amino acid
DN399_03245	COG2188	Transcriptional regulator
DN399_03250	COG1263	PTS System
DN399_03250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN399_03255	COG0366	Alpha amylase catalytic
DN399_03270	COG0697	spore germination
DN399_03275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN399_03280	COG1115	amino acid carrier protein
DN399_03290	COG1126	abc transporter atp-binding protein
DN399_03295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN399_03300	COG0765	amino acid transport
DN399_03305	COG0765	amino acid transport
DN399_03310	COG0833	amino acid
DN399_03325	COG2378	regulation of single-species biofilm formation
DN399_03330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN399_03335	COG5002	protein histidine kinase activity
DN399_03360	COG0659	secondary active sulfate transmembrane transporter activity
DN399_03375	COG2271	Major facilitator Superfamily
DN399_03380	COG1846	Transcriptional regulator
DN399_03385	COG0477	Major facilitator Superfamily
DN399_03390	COG1609	Transcriptional regulator
DN399_03395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN399_03410	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN399_03415	COG1879	ABC-type sugar transport system periplasmic component
DN399_03420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DN399_03440	COG1063	alcohol dehydrogenase
DN399_03490	COG0840	transmembrane signaling receptor activity
DN399_03495	COG3583	domain protein
DN399_03495	COG3584	3D domain protein
DN399_03500	COG1476	TRANSCRIPTIONal
DN399_03520	COG3104	oligopeptide transport
DN399_03525	COG1114	Component of the transport system for branched-chain amino acids
DN399_03540	COG1113	amino acid transport
DN399_03545	COG2252	PERMEase
DN399_03560	COG2153	protein acetylation
DN399_03570	COG0569	domain protein
DN399_03570	COG0475	glutathione-regulated potassium exporter activity
DN399_03580	COG1845	cytochrome c oxidase, subunit III
DN399_03585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DN399_03595	COG0833	amino acid
DN399_03600	COG4990	cell redox homeostasis
DN399_03615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN399_03620	COG0697	spore germination
DN399_03625	COG0531	amino acid
DN399_03635	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN399_03640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN399_03645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DN399_03645	COG1918	ferrous iron import across plasma membrane
DN399_03650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN399_03655	COG0573	inorganic phosphate transmembrane transporter activity
DN399_03660	COG0581	inorganic phosphate transmembrane transporter activity
DN399_03670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN399_03790	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
DN399_03810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN399_03815	COG1116	anion transmembrane transporter activity
DN399_03820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN399_03825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN399_03830	COG0352	thiamine-phosphate diphosphorylase activity
DN399_03835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN399_03840	COG2104	thiamine diphosphate biosynthetic process
DN399_03850	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN399_03855	COG0351	phosphomethylpyrimidine kinase
DN399_03895	COG2205	protein histidine kinase activity
DN399_03900	COG2814	Major facilitator Superfamily
DN399_03905	COG1846	Transcriptional regulator
DN399_03915	COG2252	PERMEase
DN399_03920	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_03935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN399_03940	COG1621	beta-fructofuranosidase activity
DN399_03945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN399_03945	COG1263	PTS System
DN399_03950	COG1609	Transcriptional regulator
DN399_04000	COG0778	Nitroreductase
DN399_04005	COG2719	SpoVR family
DN399_04015	COG3591	Belongs to the peptidase S1B family
DN399_04040	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN399_04045	COG1937	Protein conserved in bacteria
DN399_04050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN399_04050	COG0425	Belongs to the sulfur carrier protein TusA family
DN399_04055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN399_04055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_04060	COG0425	Belongs to the sulfur carrier protein TusA family
DN399_04065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN399_04065	COG0425	Belongs to the sulfur carrier protein TusA family
DN399_04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN399_04075	COG2210	Belongs to the sulfur carrier protein TusA family
DN399_04080	COG0730	response to heat
DN399_04090	COG1316	TRANSCRIPTIONal
DN399_04095	COG0604	alcohol dehydrogenase
DN399_04100	COG1283	sodium-dependent phosphate transmembrane transporter activity
DN399_04120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN399_04120	COG3711	transcriptional antiterminator
DN399_04125	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN399_04130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN399_04155	COG3584	3D domain protein
DN399_04155	COG1388	LysM domain
DN399_04160	COG0577	efflux transmembrane transporter activity
DN399_04165	COG1136	(ABC) transporter
DN399_04175	COG5522	Integral membrane protein (intg_mem_TP0381)
DN399_04190	COG1114	Component of the transport system for branched-chain amino acids
DN399_04195	COG3546	catalase activity
DN399_04230	COG0586	Pfam SNARE associated Golgi protein
DN399_04260	COG0531	amino acid
DN399_04265	COG0475	glutathione-regulated potassium exporter activity
DN399_04275	COG1737	Transcriptional regulator
DN399_04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN399_04285	COG1263	PTS System
DN399_04295	COG2259	Doxx family
DN399_04315	COG1522	sequence-specific DNA binding
DN399_04320	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DN399_04320	COG0165	Argininosuccinate lyase
DN399_04325	COG0300	oxidoreductase activity
DN399_04340	COG2076	Multidrug Resistance protein
DN399_04350	COG1309	transcriptional regulator
DN399_04355	COG2814	Major facilitator Superfamily
DN399_04360	COG1733	regulation of RNA biosynthetic process
DN399_04375	COG4533	DNA binding
DN399_04380	COG2211	Major facilitator Superfamily
DN399_04400	COG0531	amino acid
DN399_04415	COG1012	belongs to the aldehyde dehydrogenase family
DN399_04430	COG1132	(ABC) transporter
DN399_04435	COG1132	(ABC) transporter
DN399_04445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN399_04450	COG0765	amino acid transport
DN399_04455	COG1126	abc transporter atp-binding protein
DN399_04470	COG0189	ligase activity
DN399_04500	COG0028	Belongs to the TPP enzyme family
DN399_04505	COG3527	Alpha-acetolactate decarboxylase
DN399_04520	COG0561	phosphatase activity
DN399_04530	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN399_04530	COG3409	Peptidoglycan-binding domain 1 protein
DN399_04535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN399_04540	COG0318	PFAM AMP-dependent synthetase and ligase
DN399_04555	COG0659	secondary active sulfate transmembrane transporter activity
DN399_04560	COG2244	polysaccharide biosynthetic process
DN399_04585	COG1024	Enoyl-CoA hydratase
DN399_04605	COG1363	Peptidase, m42
DN399_04640	COG0601	transmembrane transport
DN399_04645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN399_04650	COG0444	Belongs to the ABC transporter superfamily
DN399_04655	COG4608	Belongs to the ABC transporter superfamily
DN399_04665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_04685	COG0477	Major facilitator Superfamily
DN399_04690	COG3290	protein histidine kinase activity
DN399_04695	COG4565	transcriptional regulatory protein
DN399_04700	COG3181	Tripartite tricarboxylate transporter family receptor
DN399_04735	COG0789	Transcriptional regulator
DN399_04735	COG4978	Transcriptional regulator
DN399_04750	COG0305	Participates in initiation and elongation during chromosome replication
DN399_04775	COG0477	Major facilitator Superfamily
DN399_04790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_04815	COG1073	alpha beta
DN399_04855	COG1183	phosphatidylcholine synthase activity
DN399_04875	COG2376	Dihydroxyacetone kinase
DN399_04890	COG2376	Dihydroxyacetone kinase
DN399_04930	COG2373	Large extracellular alpha-helical protein
DN399_04950	COG0596	Alpha beta hydrolase
DN399_05020	COG1191	sigma factor activity
DN399_05030	COG2208	phosphoserine phosphatase activity
DN399_05035	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DN399_05040	COG0784	Response regulator, receiver
DN399_05040	COG2205	protein histidine kinase activity
DN399_05040	COG5002	protein histidine kinase activity
DN399_05060	COG0393	Putative heavy-metal-binding
DN399_05075	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DN399_05095	COG0420	3'-5' exonuclease activity
DN399_05100	COG4717	serine-type aminopeptidase activity
DN399_05110	COG0346	lactoylglutathione lyase activity
DN399_05115	COG0346	lactoylglutathione lyase activity
DN399_05120	COG0457	Tetratricopeptide repeat
DN399_05135	COG2267	carboxylic ester hydrolase activity
DN399_05150	COG2140	Oxalate decarboxylase
DN399_05155	COG3620	sequence-specific DNA binding
DN399_05160	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
DN399_05165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DN399_05175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DN399_05180	COG1695	Transcriptional regulator
DN399_05190	COG1595	DNA-templated transcription, initiation
DN399_05210	COG1033	growth of symbiont in host cell
DN399_05210	COG2409	Drug exporters of the RND superfamily
DN399_05215	COG3973	AAA domain
DN399_05250	COG4980	gas vesicle protein
DN399_05255	COG0537	adenosine 5'-monophosphoramidase activity
DN399_05260	COG1131	(ABC) transporter
DN399_05265	COG4473	ABC transporter
DN399_05285	COG3402	PFAM membrane-flanked domain
DN399_05290	COG3428	Bacterial PH domain
DN399_05330	COG0697	spore germination
DN399_05335	COG3402	PFAM membrane-flanked domain
DN399_05340	COG3428	Bacterial PH domain
DN399_05345	COG2329	Antibiotic biosynthesis monooxygenase
DN399_05350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN399_05390	COG1309	transcriptional regulator
DN399_05395	COG1511	domain protein
DN399_05425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_05430	COG1609	Transcriptional regulator
DN399_05440	COG1234	tRNA 3'-trailer cleavage
DN399_05445	COG0095	Lipoate-protein ligase
DN399_05455	COG0318	PFAM AMP-dependent synthetase and ligase
DN399_05465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DN399_05475	COG4208	sulfate ABC transporter
DN399_05555	COG1408	metallophosphoesterase
DN399_05560	COG1078	dGTPase activity
DN399_05570	COG1595	DNA-templated transcription, initiation
DN399_05575	COG3708	Transcriptional regulator
DN399_05575	COG2207	Transcriptional regulator
DN399_05580	COG2205	protein histidine kinase activity
DN399_05585	COG0745	RESPONSE REGULATOR receiver
DN399_05605	COG0501	Belongs to the peptidase M48B family
DN399_05610	COG0840	transmembrane signaling receptor activity
DN399_05615	COG3693	PFAM glycoside hydrolase, family 10
DN399_05625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DN399_05630	COG2224	Isocitrate lyase
DN399_05645	COG1278	Cold shock
DN399_05665	COG0398	Pfam SNARE associated Golgi protein
DN399_05725	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN399_05750	COG0367	asparagine synthase
DN399_05760	COG0753	catalase activity
DN399_05765	COG0004	ammonium transporteR
DN399_05790	COG2996	Protein conserved in bacteria
DN399_05805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_05820	COG0561	phosphatase activity
DN399_05840	COG2267	carboxylic ester hydrolase activity
DN399_05860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN399_05865	COG5504	Zn-dependent protease
DN399_05880	COG0180	Tryptophanyl-tRNA synthetase
DN399_05895	COG4166	transmembrane transport
DN399_05900	COG0601	transmembrane transport
DN399_05905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN399_05910	COG0444	Belongs to the ABC transporter superfamily
DN399_05915	COG4608	Belongs to the ABC transporter superfamily
DN399_05920	COG0534	Mate efflux family protein
DN399_05925	COG4166	transmembrane transport
DN399_05935	COG1393	Belongs to the ArsC family
DN399_05940	COG0861	Integral membrane protein TerC family
DN399_05960	COG1164	Oligoendopeptidase f
DN399_05970	COG2346	COG2346, Truncated hemoglobins
DN399_05975	COG4116	CYTH
DN399_05985	COG2357	RelA SpoT domain protein
DN399_05995	COG0564	pseudouridine synthase activity
DN399_06010	COG0772	Belongs to the SEDS family
DN399_06015	COG1216	Glycosyl transferase, family 2
DN399_06035	COG0457	Tetratricopeptide repeat
DN399_06035	COG0463	Glycosyl transferase, family 2
DN399_06055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DN399_06070	COG1091	dTDP-4-dehydrorhamnose reductase activity
DN399_06115	COG2153	protein acetylation
DN399_06125	COG2382	esterase
DN399_06150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN399_06165	COG0512	Glutamine amidotransferase of anthranilate synthase
DN399_06165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DN399_06200	COG1620	l-lactate permease
DN399_06205	COG5634	Uncharacterized conserved protein (DUF2278)
DN399_06255	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN399_06265	COG1476	TRANSCRIPTIONal
DN399_06325	COG1686	Belongs to the peptidase S11 family
DN399_06330	COG0681	Belongs to the peptidase S26 family
DN399_06365	COG1012	belongs to the aldehyde dehydrogenase family
DN399_06375	COG1176	ABC-type spermidine putrescine transport system, permease component I
DN399_06380	COG1177	transmembrane transport
DN399_06385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DN399_06395	COG2409	Drug exporters of the RND superfamily
DN399_06405	COG0564	pseudouridine synthase activity
DN399_06415	COG2340	Cysteine-rich secretory protein family
DN399_06420	COG0247	lactate metabolic process
DN399_06425	COG0277	FAD linked oxidase domain protein
DN399_06430	COG3835	regulator
DN399_06440	COG0745	RESPONSE REGULATOR receiver
DN399_06445	COG5002	protein histidine kinase activity
DN399_06450	COG2186	Transcriptional regulator
DN399_06470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DN399_06480	COG2116	formate transmembrane transporter activity
DN399_06485	COG0861	Integral membrane protein TerC family
DN399_06490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN399_06500	COG2030	dehydratase
DN399_06520	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_06525	COG3243	poly(R)-hydroxyalkanoic acid synthase
DN399_06535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN399_06550	COG1840	ABC-type Fe3 transport system, periplasmic component
DN399_06555	COG3842	ATPase activity
DN399_06580	COG1349	DNA-binding transcription factor activity
DN399_06590	COG0235	Class ii aldolase
DN399_06600	COG2861	carbohydrate metabolic process
DN399_06610	COG3852	Histidine kinase
DN399_06615	COG1846	Transcriptional regulator
DN399_06625	COG2318	DinB family
DN399_06630	COG5002	protein histidine kinase activity
DN399_06640	COG0720	synthase
DN399_06655	COG4873	Protein conserved in bacteria
DN399_06685	COG1780	Probably involved in ribonucleotide reductase function
DN399_06690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN399_06695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN399_06700	COG1725	Transcriptional regulator
DN399_06705	COG1131	(ABC) transporter
DN399_06715	COG1131	(ABC) transporter
DN399_06720	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DN399_06735	COG1522	sequence-specific DNA binding
DN399_06745	COG1335	isochorismatase
DN399_06755	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN399_06760	COG2070	2-Nitropropane dioxygenase
DN399_06765	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DN399_06775	COG1696	Membrane protein involved in D-alanine export
DN399_06795	COG0716	FMN binding
DN399_06840	COG1846	Transcriptional regulator
DN399_06850	COG1301	dicarboxylic acid transport
DN399_06855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN399_06860	COG4709	membrane
DN399_06865	COG3874	Sporulation protein YtfJ
DN399_06885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN399_06890	COG0028	Belongs to the TPP enzyme family
DN399_06895	COG0440	acetolactate synthase activity
DN399_06970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DN399_06985	COG1183	phosphatidylcholine synthase activity
DN399_06990	COG1368	sulfuric ester hydrolase activity
DN399_07000	COG0019	diaminopimelate decarboxylase activity
DN399_07020	COG0529	Catalyzes the synthesis of activated sulfate
DN399_07025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN399_07045	COG1648	precorrin-2 dehydrogenase activity
DN399_07050	COG0733	neurotransmitter:sodium symporter activity
DN399_07070	COG1757	Na H antiporter
DN399_07085	COG4758	membrane
DN399_07090	COG4585	Histidine kinase
DN399_07095	COG2197	response regulator
DN399_07105	COG1114	Component of the transport system for branched-chain amino acids
DN399_07155	COG0730	response to heat
DN399_07160	COG0306	phosphate transporter
DN399_07165	COG1392	Phosphate transport regulator
DN399_07170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN399_07185	COG3852	Histidine kinase
DN399_07190	COG1801	Protein of unknown function DUF72
DN399_07200	COG0582	viral genome integration into host DNA
DN399_07205	COG5002	protein histidine kinase activity
DN399_07225	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DN399_07225	COG0392	lysyltransferase activity
DN399_07240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN399_07245	COG1686	Belongs to the peptidase S11 family
DN399_07250	COG2715	membrane protein required for spore maturation
DN399_07255	COG0700	Nucleoside recognition
DN399_07260	COG1187	pseudouridine synthase activity
DN399_07270	COG1333	cytochrome c biogenesis protein
DN399_07275	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN399_07280	COG0745	RESPONSE REGULATOR receiver
DN399_07285	COG5002	protein histidine kinase activity
DN399_07290	COG2096	Adenosyltransferase
DN399_07305	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DN399_07310	COG1141	Ferredoxin
DN399_07320	COG0514	ATP-dependent DNA helicase (RecQ)
DN399_07325	COG1266	CAAX protease self-immunity
DN399_07335	COG1408	metallophosphoesterase
DN399_07340	COG0789	Transcriptional regulator
DN399_07350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN399_07370	COG0492	ferredoxin-NADP+ reductase activity
DN399_07375	COG0252	asparaginase activity
DN399_07440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN399_07455	COG0142	geranyltranstransferase activity
DN399_07465	COG0142	geranyltranstransferase activity
DN399_07490	COG0457	Tetratricopeptide repeat
DN399_07510	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DN399_07515	COG2010	Cytochrome c
DN399_07515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DN399_07520	COG4347	Protein of unknown function (DUF1405)
DN399_07535	COG2738	Putative neutral zinc metallopeptidase
DN399_07545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_07555	COG1694	Mazg nucleotide pyrophosphohydrolase
DN399_07575	COG0438	transferase activity, transferring glycosyl groups
DN399_07610	COG1199	ATP-dependent helicase activity
DN399_07610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DN399_07630	COG3935	DnaD domain protein
DN399_07635	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DN399_07645	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN399_07645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN399_07700	COG0116	Belongs to the methyltransferase superfamily
DN399_07710	COG1199	ATP-dependent helicase activity
DN399_07715	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DN399_07725	COG0024	Methionine aminopeptidase
DN399_07735	COG2233	PERMEase
DN399_07740	COG2311	Membrane
DN399_07745	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN399_07755	COG0456	acetyltransferase
DN399_07790	COG0754	glutathionylspermidine amidase activity
DN399_07810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN399_07825	COG3944	biosynthesis protein
DN399_07835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN399_07850	COG1215	transferase activity, transferring glycosyl groups
DN399_07855	COG0438	transferase activity, transferring glycosyl groups
DN399_07870	COG0454	-acetyltransferase
DN399_07890	COG0328	RNA-DNA hybrid ribonuclease activity
DN399_07925	COG3403	YqcI/YcgG family
DN399_07930	COG1280	lysine exporter protein (LysE YggA)
DN399_07950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN399_07955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN399_07965	COG0475	glutathione-regulated potassium exporter activity
DN399_07970	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN399_07975	COG4978	Transcriptional regulator
DN399_07975	COG0789	Transcriptional regulator
DN399_07985	COG2323	membrane
DN399_07990	COG1434	Gram-negative-bacterium-type cell wall biogenesis
DN399_08025	COG1923	regulation of RNA biosynthetic process
DN399_08035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DN399_08040	COG1360	Flagellar Motor Protein
DN399_08045	COG2201	protein-glutamate methylesterase activity
DN399_08050	COG2198	Histidine kinase
DN399_08050	COG0643	Histidine kinase
DN399_08055	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN399_08055	COG1776	CheC inhibitor of MCP methylation
DN399_08070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DN399_08090	COG1256	bacterial-type flagellum assembly
DN399_08095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN399_08115	COG1815	bacterial-type flagellum-dependent cell motility
DN399_08120	COG1558	bacterial-type flagellum-dependent cell motility
DN399_08125	COG1677	Flagellar hook-basal body complex protein FliE
DN399_08130	COG1766	The M ring may be actively involved in energy transduction
DN399_08135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN399_08145	COG1157	protein secretion by the type III secretion system
DN399_08165	COG1749	Flagellar hook protein flgE
DN399_08180	COG0784	Response regulator, receiver
DN399_08180	COG0835	chemotaxis
DN399_08190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN399_08195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DN399_08200	COG0741	lytic transglycosylase activity
DN399_08210	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN399_08215	COG1776	CheC inhibitor of MCP methylation
DN399_08215	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN399_08225	COG1338	Plays a role in the flagellum-specific transport system
DN399_08230	COG1987	bacterial-type flagellum assembly
DN399_08240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN399_08245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN399_08250	COG1419	protein localization to endoplasmic reticulum
DN399_08255	COG4786	Flagellar basal body rod
DN399_08260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DN399_08295	COG2329	Antibiotic biosynthesis monooxygenase
DN399_08340	COG1234	tRNA 3'-trailer cleavage
DN399_08370	COG0406	alpha-ribazole phosphatase activity
DN399_08400	COG0367	asparagine synthase
DN399_08430	COG1802	Transcriptional regulator
DN399_08435	COG0697	spore germination
DN399_08445	COG0523	cobalamin synthesis protein
DN399_08455	COG0701	Predicted permease
DN399_08470	COG1757	Na H antiporter
DN399_08475	COG0789	Transcriptional regulator
DN399_08500	COG0534	Mate efflux family protein
DN399_08505	COG3340	Belongs to the peptidase S51 family
DN399_08525	COG0785	Cytochrome C biogenesis protein
DN399_08530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN399_08550	COG2733	membrane
DN399_08580	COG2197	response regulator
DN399_08590	COG1131	(ABC) transporter
DN399_08610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN399_08615	COG0528	UMP kinase activity
DN399_08625	COG1027	Aspartate ammonia-lyase
DN399_08630	COG0281	malic enzyme
DN399_08635	COG4191	Histidine kinase
DN399_08640	COG0784	Response regulator, receiver
DN399_08645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN399_08700	COG2814	Major facilitator Superfamily
DN399_08715	COG1695	Transcriptional regulator
DN399_08730	COG0477	Major facilitator Superfamily
DN399_08740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN399_08745	COG2223	nitrite transmembrane transporter activity
DN399_08750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN399_08770	COG0733	neurotransmitter:sodium symporter activity
DN399_08780	COG5566	PFAM Mor transcription activator
DN399_08785	COG2323	membrane
DN399_08800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN399_08810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN399_08815	COG0028	Belongs to the TPP enzyme family
DN399_08835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN399_08860	COG2814	Major facilitator Superfamily
DN399_08865	COG3384	dioxygenase
DN399_08875	COG3279	Response regulator of the LytR AlgR family
DN399_08880	COG0427	acetyl-CoA hydrolase
DN399_08900	COG4166	transmembrane transport
DN399_08905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_08925	COG1914	H( )-stimulated, divalent metal cation uptake system
DN399_08940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN399_08945	COG0531	amino acid
DN399_08975	COG2309	aminopeptidase activity
DN399_08990	COG0456	acetyltransferase
DN399_09010	COG1309	transcriptional regulator
DN399_09015	COG2390	Transcriptional regulator
DN399_09025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN399_09030	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DN399_09065	COG4846	Membrane protein involved in cytochrome C biogenesis
DN399_09085	COG0583	DNA-binding transcription factor activity
DN399_09100	COG0006	proline dipeptidase activity
DN399_09110	COG2132	Multicopper oxidase
DN399_09155	COG1114	Component of the transport system for branched-chain amino acids
DN399_09165	COG1276	copper resistance
DN399_09165	COG2372	response to copper ion
DN399_09170	COG4549	nuclear export factor GLE1
DN399_09175	COG0697	spore germination
DN399_09180	COG0583	DNA-binding transcription factor activity
DN399_09185	COG1959	2 iron, 2 sulfur cluster binding
DN399_09190	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN399_09195	COG0778	Nitroreductase
DN399_09205	COG0628	permease
DN399_09215	COG1231	oxidoreductase activity
DN399_09225	COG0523	cobalamin synthesis protein
DN399_09235	COG0411	ABC transporter
DN399_09255	COG0583	DNA-binding transcription factor activity
DN399_09265	COG1942	4-Oxalocrotonate Tautomerase
DN399_09280	COG1271	oxidase subunit
DN399_09285	COG1294	oxidase, subunit
DN399_09290	COG4988	ABC transporter
DN399_09295	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DN399_09305	COG1216	Glycosyl transferase, family 2
DN399_09345	COG1686	Belongs to the peptidase S11 family
DN399_09360	COG1388	LysM domain
DN399_09360	COG0791	NLP P60 protein
DN399_09370	COG1132	(ABC) transporter
DN399_09375	COG0745	RESPONSE REGULATOR receiver
DN399_09380	COG5002	protein histidine kinase activity
DN399_09385	COG0300	oxidoreductase activity
DN399_09395	COG0726	polysaccharide deacetylase
DN399_09415	COG0460	homoserine dehydrogenase
DN399_09440	COG1316	TRANSCRIPTIONal
DN399_09450	COG0745	RESPONSE REGULATOR receiver
DN399_09455	COG5002	protein histidine kinase activity
DN399_09460	COG0726	polysaccharide deacetylase
DN399_09470	COG1285	pathogenesis
DN399_09475	COG1247	-acetyltransferase
DN399_09485	COG4264	IucA IucC family
DN399_09490	COG0318	PFAM AMP-dependent synthetase and ligase
DN399_09505	COG1082	Xylose isomerase domain protein TIM barrel
DN399_09515	COG2814	Major facilitator Superfamily
DN399_09520	COG1279	arginine transmembrane transporter activity
DN399_09525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_09535	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN399_09570	COG0577	efflux transmembrane transporter activity
DN399_09575	COG2002	toxin-antitoxin pair type II binding
DN399_09580	COG1404	Belongs to the peptidase S8 family
DN399_09595	COG3152	Membrane
DN399_09620	COG0840	transmembrane signaling receptor activity
DN399_09635	COG3949	Membrane
DN399_09640	COG0783	Belongs to the Dps family
DN399_09655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN399_09665	COG1231	oxidoreductase activity
DN399_09670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_09675	COG4989	oxidoreductase activity
DN399_09685	COG0523	cobalamin synthesis protein
DN399_09690	COG0456	acetyltransferase
DN399_09695	COG0803	Belongs to the bacterial solute-binding protein 9 family
DN399_09700	COG0702	epimerase
DN399_09710	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN399_09720	COG4166	transmembrane transport
DN399_09745	COG5337	Spore coat protein CotH
DN399_09750	COG1051	belongs to the nudix hydrolase family
DN399_09755	COG0586	Pfam SNARE associated Golgi protein
DN399_09760	COG2244	polysaccharide biosynthetic process
DN399_09770	COG0701	Predicted permease
DN399_09775	COG3689	TIGRFAM TIGR03943 family protein
DN399_09780	COG1607	acyl-coa hydrolase
DN399_09790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN399_09805	COG0702	epimerase
DN399_09810	COG2839	Protein conserved in bacteria
DN399_09815	COG1253	flavin adenine dinucleotide binding
DN399_09830	COG1114	Component of the transport system for branched-chain amino acids
DN399_09835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN399_09855	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN399_09865	COG1876	peptidase activity
DN399_09875	COG0154	amidase activity
DN399_09880	COG2211	Major facilitator Superfamily
DN399_09895	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN399_09905	COG0561	phosphatase activity
DN399_09920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN399_09940	COG1819	glycosyl
DN399_09945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_09950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_09980	COG0456	acetyltransferase
DN399_10000	COG1511	domain protein
DN399_10000	COG0842	Transport permease protein
DN399_10015	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN399_10070	COG3874	Sporulation protein YtfJ
DN399_10095	COG2226	methyltransferase
DN399_10115	COG1082	Xylose isomerase domain protein TIM barrel
DN399_10120	COG0346	lactoylglutathione lyase activity
DN399_10130	COG0604	alcohol dehydrogenase
DN399_10135	COG1595	DNA-templated transcription, initiation
DN399_10160	COG0386	Belongs to the glutathione peroxidase family
DN399_10165	COG1305	Transglutaminase-like
DN399_10170	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
DN399_10175	COG0714	Associated with various cellular activities
DN399_10180	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DN399_10185	COG1140	nitrate reductase beta subunit
DN399_10190	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DN399_10195	COG2181	nitrate reductase activity
DN399_10200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN399_10205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN399_10210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN399_10215	COG0303	'Molybdopterin
DN399_10220	COG0314	molybdopterin synthase activity
DN399_10230	COG2223	nitrite transmembrane transporter activity
DN399_10255	COG1648	precorrin-2 dehydrogenase activity
DN399_10265	COG1587	Uroporphyrinogen-III synthase
DN399_10265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DN399_10270	COG2146	nitrite reductase [NAD(P)H] activity
DN399_10275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN399_10280	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
DN399_10315	COG2359	stage V sporulation protein S
DN399_10340	COG0457	Tetratricopeptide repeat
DN399_10355	COG1418	mRNA catabolic process
DN399_10360	COG0488	(ABC) transporter
DN399_10375	COG0629	single-stranded DNA binding
DN399_10385	COG1413	lyase activity
DN399_10400	COG2136	Putative SAM-dependent methyltransferase
DN399_10400	COG2521	methyltransferase
DN399_10405	COG0018	arginyl-trna synthetase
DN399_10460	COG0017	Asparaginyl-tRNA synthetase
DN399_10465	COG0733	neurotransmitter:sodium symporter activity
DN399_10490	COG2610	gluconate transmembrane transporter activity
DN399_10500	COG1794	racemase activity, acting on amino acids and derivatives
DN399_10510	COG0456	acetyltransferase
DN399_10520	COG3655	Transcriptional regulator
DN399_10525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DN399_10535	COG1131	(ABC) transporter
DN399_10540	COG4473	ABC transporter
DN399_10550	COG0546	phosphoglycolate phosphatase activity
DN399_10565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN399_10580	COG0768	penicillin binding
DN399_10590	COG0204	Acyl-transferase
DN399_10595	COG1272	protein, Hemolysin III
DN399_10605	COG0805	protein transport
DN399_10615	COG1307	EDD domain protein, DegV family
DN399_10625	COG1999	signal sequence binding
DN399_10630	COG0071	Belongs to the small heat shock protein (HSP20) family
DN399_10635	COG0367	asparagine synthase
DN399_10650	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN399_10655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN399_10660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN399_10680	COG1335	isochorismatase
DN399_10695	COG0668	transmembrane transport
DN399_10700	COG4585	Histidine kinase
DN399_10700	COG2203	Gaf domain
DN399_10705	COG2197	response regulator
DN399_10710	COG1737	Transcriptional regulator
DN399_10715	COG0384	phenazine biosynthesis protein PhzF
DN399_10720	COG1064	alcohol dehydrogenase
DN399_10745	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DN399_10780	COG1125	glycine betaine transport
DN399_10780	COG0517	IMP dehydrogenase activity
DN399_10785	COG1174	glycine betaine transport
DN399_10820	COG1253	flavin adenine dinucleotide binding
DN399_10825	COG1012	belongs to the aldehyde dehydrogenase family
DN399_10830	COG5506	Protein of unknown function (DUF1694)
DN399_10845	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN399_10850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DN399_10855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DN399_10860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN399_10865	COG0456	acetyltransferase
DN399_10870	COG3829	transcription factor binding
DN399_10875	COG1509	lysine 2,3-aminomutase activity
DN399_10910	COG3064	Membrane
DN399_10910	COG0515	serine threonine protein kinase
DN399_10910	COG4991	sh3 domain protein
DN399_10920	COG0671	phosphoesterase, PA-phosphatase related
DN399_10925	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN399_10930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN399_11010	COG0300	oxidoreductase activity
DN399_11030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN399_11030	COG4499	WXG100 protein secretion system (Wss), protein YukC
DN399_11040	COG2814	Major facilitator Superfamily
DN399_11045	COG4841	protein insertion into membrane
DN399_11050	COG0372	Belongs to the citrate synthase family
DN399_11055	COG2079	MmgE PrpD family protein
DN399_11060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
DN399_11065	COG1960	acyl-CoA dehydrogenase activity
DN399_11070	COG2084	Dehydrogenase
DN399_11080	COG1280	lysine exporter protein (LysE YggA)
DN399_11085	COG1024	Enoyl-CoA hydratase
DN399_11100	COG0420	3'-5' exonuclease activity
DN399_11105	COG0419	ATPase involved in DNA repair
DN399_11130	COG2223	nitrite transmembrane transporter activity
DN399_11135	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_11140	COG1169	isochorismate synthase
DN399_11145	COG1021	2,3-dihydroxybenzoate-AMP ligase
DN399_11150	COG3433	isochorismatase activity
DN399_11150	COG1535	isochorismatase
DN399_11155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN399_11160	COG3251	PFAM MbtH domain protein
DN399_11165	COG2814	Major facilitator Superfamily
DN399_11180	COG0776	regulation of translation
DN399_11190	COG2318	DinB family
DN399_11200	COG1115	amino acid carrier protein
DN399_11220	COG1187	pseudouridine synthase activity
DN399_11225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DN399_11230	COG1136	(ABC) transporter
DN399_11240	COG2814	Major facilitator Superfamily
DN399_11255	COG0028	Belongs to the TPP enzyme family
DN399_11295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN399_11305	COG2267	carboxylic ester hydrolase activity
DN399_11315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_11345	COG1247	-acetyltransferase
DN399_11375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_11400	COG0561	phosphatase activity
DN399_11410	COG0583	DNA-binding transcription factor activity
DN399_11415	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN399_11435	COG0583	DNA-binding transcription factor activity
DN399_11440	COG2258	MOSC domain
DN399_11455	COG1132	(ABC) transporter
DN399_11460	COG1132	(ABC) transporter
DN399_11490	COG1396	sequence-specific DNA binding
DN399_11525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN399_11530	COG1595	DNA-templated transcription, initiation
DN399_11550	COG1649	PFAM Uncharacterised BCR, COG1649
DN399_11575	COG2971	BadF BadG BcrA BcrD
DN399_11595	COG1846	Transcriptional regulator
DN399_11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_11685	COG0582	viral genome integration into host DNA
DN399_11710	COG4824	toxin secretion phage lysis holin
DN399_11715	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN399_11715	COG3409	Peptidoglycan-binding domain 1 protein
DN399_11715	COG1388	LysM domain
DN399_11730	COG0500	methyltransferase
DN399_11730	COG3615	Tellurite resistance protein tehB
DN399_11745	COG3961	Belongs to the TPP enzyme family
DN399_11750	COG1846	Transcriptional regulator
DN399_11775	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN399_11800	COG2002	toxin-antitoxin pair type II binding
DN399_11810	COG0730	response to heat
DN399_11815	COG0110	maltose O-acetyltransferase activity
DN399_11830	COG2814	Major facilitator Superfamily
DN399_11880	COG2312	Erythromycin esterase
DN399_11890	COG0741	lytic transglycosylase activity
DN399_11895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_11960	COG1760	l-serine dehydratase
DN399_11965	COG1760	l-serine dehydratase
DN399_11970	COG0814	amino acid
DN399_11980	COG0840	transmembrane signaling receptor activity
DN399_12005	COG1309	transcriptional regulator
DN399_12015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN399_12020	COG0768	penicillin binding
DN399_12025	COG1595	DNA-templated transcription, initiation
DN399_12035	COG0768	penicillin binding
DN399_12050	COG1408	metallophosphoesterase
DN399_12060	COG1131	(ABC) transporter
DN399_12070	COG1309	transcriptional regulator
DN399_12085	COG1960	acyl-CoA dehydrogenase activity
DN399_12090	COG0439	Biotin carboxylase
DN399_12095	COG0511	ligase activity, forming carbon-carbon bonds
DN399_12100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DN399_12105	COG1024	Enoyl-CoA hydratase
DN399_12110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DN399_12115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN399_12145	COG0572	uridine kinase
DN399_12170	COG1686	Belongs to the peptidase S11 family
DN399_12195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DN399_12210	COG3227	Zinc metalloprotease (Elastase)
DN399_12215	COG2207	Transcriptional regulator
DN399_12245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN399_12255	COG2814	Major facilitator Superfamily
DN399_12260	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_12270	COG1733	regulation of RNA biosynthetic process
DN399_12275	COG2226	methyltransferase
DN399_12315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_12325	COG2368	4-hydroxyphenylacetate
DN399_12340	COG1063	alcohol dehydrogenase
DN399_12350	COG2323	membrane
DN399_12365	COG3386	PFAM SMP-30 Gluconolaconase
DN399_12380	COG3773	Cell wall hydrolase
DN399_12390	COG0745	RESPONSE REGULATOR receiver
DN399_12395	COG2205	protein histidine kinase activity
DN399_12415	COG1136	(ABC) transporter
DN399_12420	COG0577	efflux transmembrane transporter activity
DN399_12440	COG0460	homoserine dehydrogenase
DN399_12445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_12455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN399_12485	COG0582	viral genome integration into host DNA
DN399_12600	COG0582	viral genome integration into host DNA
DN399_12660	COG0740	serine-type endopeptidase activity
DN399_12740	COG4824	toxin secretion phage lysis holin
DN399_12795	COG2124	cytochrome p450
DN399_12835	COG0561	phosphatase activity
DN399_12840	COG5002	protein histidine kinase activity
DN399_12855	COG1819	glycosyl
DN399_12860	COG1794	racemase activity, acting on amino acids and derivatives
DN399_12885	COG2205	protein histidine kinase activity
DN399_13010	COG0745	RESPONSE REGULATOR receiver
DN399_13015	COG5002	protein histidine kinase activity
DN399_13020	COG0604	alcohol dehydrogenase
DN399_13025	COG0671	phosphoesterase, PA-phosphatase related
DN399_13070	COG0693	protein deglycase activity
DN399_13085	COG0584	glycerophosphoryl diester phosphodiesterase
DN399_13105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_13110	COG0697	spore germination
DN399_13150	COG2223	nitrite transmembrane transporter activity
DN399_13165	COG0592	DNA-directed DNA polymerase activity
DN399_13185	COG3878	Protein conserved in bacteria
DN399_13210	COG4667	esterase of the alpha-beta hydrolase superfamily
DN399_13250	COG0322	excinuclease ABC activity
DN399_13290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN399_13325	COG1011	Hydrolase
DN399_13330	COG0745	RESPONSE REGULATOR receiver
DN399_13335	COG5002	protein histidine kinase activity
DN399_13350	COG1136	(ABC) transporter
DN399_13355	COG0577	efflux transmembrane transporter activity
DN399_13360	COG1073	alpha beta
DN399_13370	COG0076	glutamate decarboxylase activity
DN399_13385	COG1523	belongs to the glycosyl hydrolase 13 family
DN399_13390	COG3227	Zinc metalloprotease (Elastase)
DN399_13395	COG0737	Belongs to the 5'-nucleotidase family
DN399_13415	COG0201	protein transport
DN399_13420	COG0697	spore germination
DN399_13425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_13430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN399_13460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_13475	COG2959	enzyme of heme biosynthesis
DN399_13480	COG3773	Cell wall hydrolase
DN399_13480	COG3409	Peptidoglycan-binding domain 1 protein
DN399_13515	COG1309	transcriptional regulator
DN399_13540	COG3284	Transcriptional regulator
DN399_13555	COG1349	DNA-binding transcription factor activity
DN399_13570	COG1959	2 iron, 2 sulfur cluster binding
DN399_13585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN399_13590	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN399_13595	COG0022	dehydrogenase e1 component
DN399_13600	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN399_13610	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_13640	COG4176	ABC-type proline glycine betaine transport system permease component
DN399_13645	COG4175	Glycine betaine
DN399_13645	COG0517	IMP dehydrogenase activity
DN399_13675	COG2153	protein acetylation
DN399_13680	COG3397	chitin binding
DN399_13685	COG1819	glycosyl
DN399_13705	COG2205	protein histidine kinase activity
DN399_13710	COG2226	methyltransferase
DN399_13715	COG2315	Protein conserved in bacteria
DN399_13760	COG0456	acetyltransferase
DN399_13765	COG3973	AAA domain
DN399_13780	COG0514	ATP-dependent DNA helicase (RecQ)
DN399_13815	COG4637	Psort location Cytoplasmic, score
DN399_13835	COG3397	chitin binding
DN399_13850	COG1162	GTPase activity
DN399_13855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN399_13860	COG1115	amino acid carrier protein
DN399_13865	COG1012	belongs to the aldehyde dehydrogenase family
DN399_13870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN399_13880	COG3938	Belongs to the proline racemase family
DN399_13885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN399_13925	COG0586	Pfam SNARE associated Golgi protein
DN399_13935	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DN399_13945	COG4166	transmembrane transport
DN399_13955	COG4948	Mandelate Racemase Muconate Lactonizing
DN399_13970	COG0667	Aldo Keto reductase
DN399_14015	COG3850	Histidine kinase
DN399_14015	COG5002	protein histidine kinase activity
DN399_14020	COG0745	RESPONSE REGULATOR receiver
DN399_14055	COG1164	Oligoendopeptidase f
DN399_14060	COG1307	EDD domain protein, DegV family
DN399_14100	COG2814	Major facilitator Superfamily
DN399_14110	COG1664	Polymer-forming cytoskeletal
DN399_14115	COG0789	Transcriptional regulator
DN399_14120	COG4533	DNA binding
DN399_14125	COG2814	Major facilitator Superfamily
DN399_14125	COG0477	Major facilitator Superfamily
DN399_14145	COG2261	transglycosylase associated protein
DN399_14160	COG2226	methyltransferase
DN399_14195	COG0436	Aminotransferase
DN399_14200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DN399_14210	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DN399_14250	COG0628	permease
DN399_14260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN399_14265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN399_14270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN399_14310	COG2746	aminoglycoside 3-N-acetyltransferase activity
DN399_14330	COG0697	spore germination
DN399_14360	COG4912	Dna alkylation repair
DN399_14365	COG0346	lactoylglutathione lyase activity
DN399_14375	COG0726	polysaccharide deacetylase
DN399_14385	COG0861	Integral membrane protein TerC family
DN399_14390	COG1368	sulfuric ester hydrolase activity
DN399_14395	COG0488	(ABC) transporter
DN399_14400	COG2409	Drug exporters of the RND superfamily
DN399_14400	COG1033	growth of symbiont in host cell
DN399_14405	COG1309	transcriptional regulator
DN399_14420	COG0287	Prephenate dehydrogenase
DN399_14435	COG1605	Chorismate mutase
DN399_14435	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN399_14485	COG1388	LysM domain
DN399_14485	COG3584	3D domain protein
DN399_14495	COG0346	lactoylglutathione lyase activity
DN399_14500	COG0277	FAD linked oxidase domain protein
DN399_14525	COG1879	ABC-type sugar transport system periplasmic component
DN399_14530	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN399_14535	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN399_14545	COG2390	Transcriptional regulator
DN399_14550	COG1070	Carbohydrate kinase
DN399_14570	COG2329	Antibiotic biosynthesis monooxygenase
DN399_14590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN399_14605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN399_14610	COG4187	Peptidase family M20/M25/M40
DN399_14615	COG1414	Transcriptional regulator
DN399_14625	COG0833	amino acid
DN399_14635	COG3239	Fatty acid desaturase
DN399_14645	COG2720	vancomycin resistance protein
DN399_14650	COG1785	Belongs to the alkaline phosphatase family
DN399_14660	COG3655	Transcriptional regulator
DN399_14675	COG4377	Putative membrane peptidase family (DUF2324)
DN399_14685	COG3279	Response regulator of the LytR AlgR family
DN399_14695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_14700	COG0346	lactoylglutathione lyase activity
DN399_14730	COG0714	Associated with various cellular activities
DN399_14755	COG0463	Glycosyl transferase, family 2
DN399_14785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DN399_14790	COG0753	catalase activity
DN399_14830	COG0714	Associated with various cellular activities
DN399_14875	COG0778	Nitroreductase
DN399_14880	COG1846	Transcriptional regulator
DN399_14905	COG3831	ATPase activity
DN399_14905	COG4884	unkown
DN399_14930	COG0456	acetyltransferase
DN399_14945	COG0697	spore germination
DN399_14950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_14990	COG0730	response to heat
DN399_15000	COG0833	amino acid
DN399_15010	COG4335	DNA alkylation repair
DN399_15100	COG1984	allophanate hydrolase subunit 2
DN399_15105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DN399_15110	COG1414	Transcriptional regulator
DN399_15125	COG0640	Transcriptional regulator
DN399_15135	COG1960	acyl-CoA dehydrogenase activity
DN399_15170	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DN399_15195	COG0574	Belongs to the PEP-utilizing enzyme family
DN399_15195	COG3848	Pyruvate phosphate dikinase
DN399_15200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_15220	COG1063	alcohol dehydrogenase
DN399_15225	COG1027	Aspartate ammonia-lyase
DN399_15230	COG0252	asparaginase activity
DN399_15235	COG1396	sequence-specific DNA binding
DN399_15270	COG5002	protein histidine kinase activity
DN399_15295	COG2207	Transcriptional regulator
DN399_15320	COG0531	amino acid
DN399_15325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN399_15335	COG0531	amino acid
DN399_15340	COG0697	spore germination
DN399_15345	COG0784	Response regulator, receiver
DN399_15350	COG4191	Histidine kinase
DN399_15355	COG2066	Belongs to the glutaminase family
DN399_15360	COG1115	amino acid carrier protein
DN399_15390	COG0737	Belongs to the 5'-nucleotidase family
DN399_15395	COG2267	carboxylic ester hydrolase activity
DN399_15400	COG1335	isochorismatase
DN399_15420	COG0583	DNA-binding transcription factor activity
DN399_15425	COG1846	Transcriptional regulator
DN399_15430	COG0598	Magnesium transport protein CorA
DN399_15450	COG1073	alpha beta
DN399_15470	COG0415	Belongs to the DNA photolyase family
DN399_15485	COG0288	reversible hydration of carbon dioxide
DN399_15495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN399_15500	COG5609	conserved protein (DUF2294)
DN399_15505	COG0726	polysaccharide deacetylase
DN399_15515	COG1575	Belongs to the MenA family. Type 1 subfamily
DN399_15530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN399_15540	COG2814	Major facilitator Superfamily
DN399_15555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN399_15555	COG3320	Male sterility
DN399_15565	COG2814	Major facilitator Superfamily
DN399_15570	COG1309	transcriptional regulator
DN399_15575	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_15580	COG1522	sequence-specific DNA binding
DN399_15595	COG0346	lactoylglutathione lyase activity
DN399_15650	COG2814	Major facilitator Superfamily
DN399_15665	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DN399_15675	COG1690	Belongs to the RtcB family
DN399_15685	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
DN399_15705	COG0577	efflux transmembrane transporter activity
DN399_15725	COG5002	protein histidine kinase activity
DN399_15725	COG3850	Histidine kinase
DN399_15735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_15745	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN399_15770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN399_15815	COG3409	Peptidoglycan-binding domain 1 protein
DN399_15815	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN399_15920	COG1876	peptidase activity
DN399_15925	COG2843	Capsule synthesis protein
DN399_15935	COG0477	Major facilitator Superfamily
DN399_15950	COG1846	Transcriptional regulator
DN399_15955	COG2814	Major facilitator Superfamily
DN399_15965	COG2031	fatty acid transporter
DN399_15975	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN399_16030	COG1288	antiporter activity
DN399_16035	COG2356	endonuclease I
DN399_16060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DN399_16080	COG1733	regulation of RNA biosynthetic process
DN399_16085	COG0778	Nitroreductase
DN399_16115	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_16125	COG1131	(ABC) transporter
DN399_16155	COG1011	Hydrolase
DN399_16190	COG0180	Tryptophanyl-tRNA synthetase
DN399_16200	COG0628	permease
DN399_16225	COG0500	methyltransferase
DN399_16265	COG1253	flavin adenine dinucleotide binding
DN399_16270	COG0789	Transcriptional regulator
DN399_16280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN399_16310	COG0697	spore germination
DN399_16320	COG1357	PFAM Pentapeptide repeats (8 copies)
DN399_16325	COG3813	Protein conserved in bacteria
DN399_16330	COG2706	6-phosphogluconolactonase activity
DN399_16335	COG1070	Carbohydrate kinase
DN399_16345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DN399_16350	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
DN399_16360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DN399_16365	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DN399_16375	COG0604	alcohol dehydrogenase
DN399_16380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN399_16385	COG0789	Transcriptional regulator
DN399_16390	COG4221	oxidoreductase activity
DN399_16400	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_16415	COG0840	transmembrane signaling receptor activity
DN399_16425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN399_16425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN399_16430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DN399_16435	COG1733	regulation of RNA biosynthetic process
DN399_16450	COG0656	L-ascorbic acid biosynthetic process
DN399_16455	COG2814	Major facilitator Superfamily
DN399_16480	COG2824	Alkylphosphonate utilization operon protein PhnA
DN399_16485	COG0659	secondary active sulfate transmembrane transporter activity
DN399_16500	COG0814	amino acid
DN399_16535	COG1733	regulation of RNA biosynthetic process
DN399_16540	COG2188	Transcriptional regulator
DN399_16545	COG0673	inositol 2-dehydrogenase activity
DN399_16550	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DN399_16555	COG1733	regulation of RNA biosynthetic process
DN399_16560	COG1733	regulation of RNA biosynthetic process
DN399_16585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_16605	COG0384	phenazine biosynthesis protein PhzF
DN399_16610	COG0318	PFAM AMP-dependent synthetase and ligase
DN399_16615	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN399_16620	COG1733	regulation of RNA biosynthetic process
DN399_16630	COG0726	polysaccharide deacetylase
DN399_16640	COG1191	sigma factor activity
DN399_16655	COG3226	Transcriptional regulator
DN399_16660	COG0076	glutamate decarboxylase activity
DN399_16685	COG1280	lysine exporter protein (LysE YggA)
DN399_16730	COG1151	hydroxylamine reductase activity
DN399_16760	COG2072	flavoprotein involved in K transport
DN399_16800	COG1113	amino acid transport
DN399_16805	COG2814	Major facilitator Superfamily
DN399_16845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN399_16850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN399_16860	COG1247	-acetyltransferase
DN399_16865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN399_16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_16880	COG3739	integral membrane protein
DN399_16900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_16915	COG0583	DNA-binding transcription factor activity
DN399_16935	COG1193	negative regulation of DNA recombination
DN399_16945	COG2162	N-hydroxyarylamine O-acetyltransferase activity
DN399_16950	COG1164	Oligoendopeptidase f
DN399_16975	COG3781	membrane
DN399_16995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN399_17020	COG0584	glycerophosphoryl diester phosphodiesterase
DN399_17030	COG0640	Transcriptional regulator
DN399_17035	COG0604	alcohol dehydrogenase
DN399_17045	COG0457	Tetratricopeptide repeat
DN399_17060	COG0277	FAD linked oxidase domain protein
DN399_17085	COG1183	phosphatidylcholine synthase activity
DN399_17095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_17095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN399_17100	COG1252	NADH dehydrogenase
DN399_17110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN399_17120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN399_17135	COG0457	Tetratricopeptide repeat
DN399_17165	COG1309	transcriptional regulator
DN399_17200	COG3852	Histidine kinase
DN399_17210	COG1285	pathogenesis
DN399_17220	COG2514	catechol 2,3-dioxygenase activity
DN399_17225	COG2720	vancomycin resistance protein
DN399_17250	COG1278	Cold shock
DN399_17260	COG0716	FMN binding
DN399_17270	COG0494	nUDIX hydrolase
DN399_17290	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_17300	COG0165	Argininosuccinate lyase
DN399_17315	COG4145	pantothenate transmembrane transporter activity
DN399_17325	COG1012	belongs to the aldehyde dehydrogenase family
DN399_17330	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_17340	COG1657	PFAM Prenyltransferase squalene oxidase
DN399_17345	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
DN399_17350	COG2962	Rard protein
DN399_17355	COG3326	Membrane
DN399_17370	COG0489	protein tyrosine kinase activity
DN399_17380	COG0314	molybdopterin synthase activity
DN399_17385	COG0303	'Molybdopterin
DN399_17390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN399_17395	COG2116	formate transmembrane transporter activity
DN399_17405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DN399_17410	COG5609	conserved protein (DUF2294)
DN399_17415	COG2427	Protein of unknown function (DUF1641)
DN399_17420	COG3383	formate dehydrogenase (NAD+) activity
DN399_17425	COG0697	spore germination
DN399_17440	COG0531	amino acid
DN399_17475	COG2226	methyltransferase
DN399_17480	COG4166	transmembrane transport
DN399_17485	COG4166	transmembrane transport
DN399_17490	COG4166	transmembrane transport
DN399_17495	COG1301	dicarboxylic acid transport
DN399_17500	COG1316	TRANSCRIPTIONal
DN399_17510	COG1595	DNA-templated transcription, initiation
DN399_17520	COG1131	(ABC) transporter
DN399_17530	COG0673	inositol 2-dehydrogenase activity
DN399_17535	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN399_17540	COG0187	DNA topoisomerase II activity
DN399_17545	COG1832	CoA-binding protein
DN399_17550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN399_17555	COG0745	RESPONSE REGULATOR receiver
DN399_17575	COG4841	protein insertion into membrane
DN399_17580	COG0824	Thioesterase
DN399_17610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN399_17620	COG2274	protein secretion by the type I secretion system
DN399_17625	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DN399_17635	COG0726	polysaccharide deacetylase
DN399_17655	COG2211	Major facilitator Superfamily
DN399_17665	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DN399_17680	COG0183	Belongs to the thiolase family
DN399_17685	COG0318	PFAM AMP-dependent synthetase and ligase
DN399_17690	COG1268	BioY protein
DN399_17695	COG0318	PFAM AMP-dependent synthetase and ligase
DN399_17725	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DN399_17745	COG0830	nickel cation binding
DN399_17785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_17800	COG5002	protein histidine kinase activity
DN399_17805	COG0400	carboxylic ester hydrolase activity
DN399_17810	COG0346	lactoylglutathione lyase activity
DN399_17815	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN399_17825	COG0069	glutamate synthase activity
DN399_17830	COG1902	pentaerythritol trinitrate reductase activity
DN399_17835	COG1329	Transcriptional regulator
DN399_17840	COG0010	Belongs to the arginase family
DN399_17895	COG4846	Membrane protein involved in cytochrome C biogenesis
DN399_17900	COG0785	Cytochrome C biogenesis protein
DN399_17925	COG1131	(ABC) transporter
DN399_17940	COG0583	DNA-binding transcription factor activity
DN399_17950	COG1346	cytolysis
DN399_17965	COG0730	response to heat
DN399_17990	COG1132	(ABC) transporter
DN399_17995	COG1132	(ABC) transporter
DN399_18020	COG3639	organic phosphonate transmembrane transporter activity
DN399_18030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN399_18035	COG0737	Belongs to the 5'-nucleotidase family
DN399_18045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DN399_18065	COG1695	Transcriptional regulator
DN399_18075	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN399_18075	COG1388	LysM domain
DN399_18075	COG3409	Peptidoglycan-binding domain 1 protein
DN399_18080	COG0739	heme binding
DN399_18085	COG0741	lytic transglycosylase activity
DN399_18115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DN399_18120	COG0174	glutamine synthetase
DN399_18125	COG0789	Transcriptional regulator
DN399_18130	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DN399_18135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN399_18140	COG2860	membrane
DN399_18145	COG0464	growth
DN399_18175	COG1388	LysM domain
DN399_18175	COG3584	3D domain protein
DN399_18180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN399_18180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN399_18180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN399_18185	COG1105	Belongs to the carbohydrate kinase PfkB family
DN399_18190	COG1349	DNA-binding transcription factor activity
DN399_18195	COG1979	alcohol dehydrogenase
DN399_18200	COG2322	membrane
DN399_18210	COG1113	amino acid transport
DN399_18225	COG1408	metallophosphoesterase
DN399_18230	COG2116	formate transmembrane transporter activity
DN399_18245	COG2217	Heavy metal translocating P-type atpase
DN399_18250	COG2608	mercury ion transmembrane transporter activity
DN399_18255	COG1937	Protein conserved in bacteria
DN399_18265	COG2819	hydrolase of the alpha beta superfamily
DN399_18270	COG1120	ATPase activity
DN399_18275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_18280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_18285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN399_18300	COG2169	Transcriptional regulator
DN399_18305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN399_18310	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DN399_18320	COG2364	Membrane
DN399_18335	COG2267	carboxylic ester hydrolase activity
DN399_18340	COG5001	Diguanylate cyclase
DN399_18340	COG3300	MHYT domain
DN399_18380	COG1346	cytolysis
DN399_18390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN399_18400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN399_18415	COG1404	Belongs to the peptidase S8 family
DN399_18420	COG3773	Cell wall hydrolase
DN399_18435	COG1368	sulfuric ester hydrolase activity
DN399_18440	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
DN399_18465	COG4550	Control of competence regulator ComK, YlbF/YmcA
DN399_18475	COG1013	pyruvate-flavodoxin oxidoreductase activity
DN399_18480	COG0674	pyruvate-flavodoxin oxidoreductase activity
DN399_18480	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DN399_18490	COG2359	stage V sporulation protein S
DN399_18495	COG1692	metallophosphoesterase
DN399_18515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DN399_18520	COG1426	Protein conserved in bacteria
DN399_18535	COG0300	oxidoreductase activity
DN399_18540	COG0612	Peptidase, M16
DN399_18545	COG0612	Peptidase, M16
DN399_18570	COG2188	Transcriptional regulator
DN399_18590	COG0740	serine-type endopeptidase activity
DN399_18595	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN399_18605	COG0527	aspartate kinase activity
DN399_18610	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN399_18615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN399_18620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN399_18625	COG1873	PFAM PRC-barrel domain
DN399_18630	COG0612	Peptidase, M16
DN399_18635	COG0726	polysaccharide deacetylase
DN399_18650	COG0196	riboflavin kinase activity
DN399_18665	COG1550	Protein conserved in bacteria
DN399_18675	COG1358	cellular component organization or biogenesis
DN399_18680	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DN399_18685	COG0195	Participates in both transcription termination and antitermination
DN399_18705	COG0750	zinc metalloprotease
DN399_18715	COG4589	Belongs to the CDS family
DN399_18760	COG4974	Belongs to the 'phage' integrase family
DN399_18770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN399_18775	COG0758	DNA mediated transformation
DN399_18780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DN399_18820	COG1837	Belongs to the UPF0109 family
DN399_18830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DN399_18840	COG0552	protein localization to endoplasmic reticulum
DN399_18845	COG1196	nuclear chromosome segregation
DN399_18860	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_18865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DN399_18880	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DN399_18885	COG1461	Dihydroxyacetone kinase
DN399_18890	COG1302	Protein conserved in bacteria
DN399_18905	COG1564	THIamine pyrophosphokinase
DN399_18910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DN399_18920	COG2815	serine threonine protein kinase
DN399_18920	COG0515	serine threonine protein kinase
DN399_18925	COG0631	protein serine/threonine phosphatase activity
DN399_18935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DN399_18935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DN399_18950	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DN399_18955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN399_18975	COG1561	YicC-like family, N-terminal region
DN399_18980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DN399_18990	COG0006	proline dipeptidase activity
DN399_19005	COG3069	C4-dicarboxylate transmembrane transporter activity
DN399_19065	COG0564	pseudouridine synthase activity
DN399_19085	COG3599	regulation of cell shape
DN399_19090	COG2302	S4 RNA-binding domain
DN399_19095	COG0762	integral membrane protein
DN399_19105	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DN399_19115	COG1873	PFAM PRC-barrel domain
DN399_19120	COG1191	sigma factor activity
DN399_19125	COG1191	sigma factor activity
DN399_19135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DN399_19140	COG0849	cell division
DN399_19160	COG0772	Belongs to the SEDS family
DN399_19180	COG0768	penicillin binding
DN399_19205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN399_19225	COG1399	metal-binding, possibly nucleic acid-binding protein
DN399_19235	COG3480	Lon protease (S16) C-terminal proteolytic domain
DN399_19240	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN399_19245	COG3314	Sporulation integral membrane protein YlbJ
DN399_19255	COG0742	ribosomal rna small subunit methyltransferase
DN399_19270	COG3679	Belongs to the UPF0342 family
DN399_19275	COG0406	alpha-ribazole phosphatase activity
DN399_19290	COG2340	Cysteine-rich secretory protein family
DN399_19305	COG3336	cytochrome c oxidase
DN399_19340	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
DN399_19350	COG0772	Belongs to the SEDS family
DN399_19360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DN399_19365	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DN399_19375	COG4896	Protein conserved in bacteria
DN399_19400	COG0483	inositol monophosphate 1-phosphatase activity
DN399_19420	COG1982	Orn Lys Arg decarboxylase major
DN399_19470	COG0022	dehydrogenase e1 component
DN399_19475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN399_19490	COG0561	phosphatase activity
DN399_19505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DN399_19510	COG0569	domain protein
DN399_19530	COG0583	DNA-binding transcription factor activity
DN399_19535	COG0517	IMP dehydrogenase activity
DN399_19545	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
DN399_19550	COG4703	Protein of unknown function (DUF1797)
DN399_19565	COG2200	EAL domain
DN399_19570	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_19575	COG1408	metallophosphoesterase
DN399_19620	COG2814	Major facilitator Superfamily
DN399_19640	COG3209	COG3209 Rhs family protein
DN399_19650	COG2205	protein histidine kinase activity
DN399_19660	COG0436	Aminotransferase
DN399_19665	COG1609	Transcriptional regulator
DN399_19670	COG3833	ABC-type maltose transport systems, permease component
DN399_19675	COG1175	transmembrane transport
DN399_19680	COG2182	Extracellular solute-binding protein
DN399_19690	COG0366	Alpha amylase catalytic
DN399_19695	COG3842	ATPase activity
DN399_19735	COG0183	Belongs to the thiolase family
DN399_19770	COG1695	Transcriptional regulator
DN399_19775	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_19795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN399_19800	COG0436	Aminotransferase
DN399_19835	COG2084	Dehydrogenase
DN399_19845	COG2199	diguanylate cyclase activity
DN399_19845	COG2203	Gaf domain
DN399_19850	COG0778	Nitroreductase
DN399_19875	COG2190	(PTS) system
DN399_19875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN399_19875	COG1263	PTS System
DN399_19880	COG3711	transcriptional antiterminator
DN399_19900	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DN399_19930	COG1547	Domain of unknown function (DUF309)
DN399_19935	COG0456	acetyltransferase
DN399_19940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN399_19945	COG4086	secreted protein
DN399_19950	COG0561	phosphatase activity
DN399_19955	COG0697	spore germination
DN399_19970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN399_19995	COG0733	neurotransmitter:sodium symporter activity
DN399_20015	COG1686	Belongs to the peptidase S11 family
DN399_20025	COG1725	Transcriptional regulator
DN399_20030	COG1131	(ABC) transporter
DN399_20050	COG1846	Transcriptional regulator
DN399_20065	COG0598	Magnesium transport protein CorA
DN399_20090	COG4974	Belongs to the 'phage' integrase family
DN399_20100	COG0735	belongs to the Fur family
DN399_20105	COG1300	Membrane
DN399_20125	COG0667	Aldo Keto reductase
DN399_20130	COG0656	L-ascorbic acid biosynthetic process
DN399_20135	COG0456	acetyltransferase
DN399_20135	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DN399_20145	COG4085	toxin activity
DN399_20145	COG1525	nuclease
DN399_20145	COG0737	Belongs to the 5'-nucleotidase family
DN399_20155	COG0596	Alpha beta hydrolase
DN399_20160	COG2056	Na+-H+ antiporter family
DN399_20165	COG1609	Transcriptional regulator
DN399_20170	COG0456	acetyltransferase
DN399_20175	COG1073	alpha beta
DN399_20190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN399_20190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN399_20195	COG0307	riboflavin synthase, alpha
DN399_20225	COG2226	methyltransferase
DN399_20225	COG1073	alpha beta
DN399_20240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DN399_20255	COG0737	Belongs to the 5'-nucleotidase family
DN399_20265	COG1522	sequence-specific DNA binding
DN399_20310	COG0300	oxidoreductase activity
DN399_20315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_20320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN399_20325	COG1760	l-serine dehydratase
DN399_20330	COG1760	l-serine dehydratase
DN399_20370	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN399_20375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_20385	COG1376	ErfK ybiS ycfS ynhG family protein
DN399_20390	COG4129	membrane
DN399_20395	COG1126	abc transporter atp-binding protein
DN399_20400	COG0765	amino acid transport
DN399_20405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN399_20425	COG2323	membrane
DN399_20430	COG0772	Belongs to the SEDS family
DN399_20435	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN399_20440	COG0022	dehydrogenase e1 component
DN399_20445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN399_20450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN399_20460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN399_20465	COG0280	phosphate acetyltransferase
DN399_20475	COG3290	protein histidine kinase activity
DN399_20475	COG3829	transcription factor binding
DN399_20485	COG0584	glycerophosphoryl diester phosphodiesterase
DN399_20490	COG3093	addiction module antidote protein HigA
DN399_20510	COG0750	zinc metalloprotease
DN399_20515	COG0497	DNA recombination
DN399_20525	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DN399_20535	COG0142	geranyltranstransferase activity
DN399_20560	COG1302	Protein conserved in bacteria
DN399_20565	COG0439	Biotin carboxylase
DN399_20570	COG0511	ligase activity, forming carbon-carbon bonds
DN399_20615	COG3854	ATPases associated with a variety of cellular activities
DN399_20640	COG0006	proline dipeptidase activity
DN399_20655	COG3872	metal-dependent enzyme
DN399_20665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN399_20680	COG1695	Transcriptional regulator
DN399_20700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN399_20710	COG1609	Transcriptional regulator
DN399_20720	COG2076	Multidrug Resistance protein
DN399_20725	COG2076	Multidrug Resistance protein
DN399_20755	COG1131	(ABC) transporter
DN399_20760	COG1725	Transcriptional regulator
DN399_20795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN399_20845	COG1204	response to ionizing radiation
DN399_20945	COG1410	methionine synthase
DN399_20945	COG0646	methionine synthase
DN399_20950	COG0646	methionine synthase
DN399_20950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DN399_20955	COG0626	cystathionine gamma-synthase activity
DN399_20960	COG0626	cystathionine gamma-synthase activity
DN399_20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_20990	COG1940	carbohydrate kinase activity
DN399_20995	COG4483	Protein conserved in bacteria
DN399_21000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DN399_21010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN399_21015	COG0704	Plays a role in the regulation of phosphate uptake
DN399_21025	COG0573	inorganic phosphate transmembrane transporter activity
DN399_21030	COG0573	inorganic phosphate transmembrane transporter activity
DN399_21035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN399_21045	COG0477	Major facilitator Superfamily
DN399_21050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN399_21060	COG5521	maltodextrose utilization protein MalA
DN399_21075	COG0735	belongs to the Fur family
DN399_21080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN399_21085	COG1121	(ABC) transporter
DN399_21090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_21120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DN399_21125	COG2384	SAM-dependent methyltransferase
DN399_21135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DN399_21140	COG0358	DNA primase activity
DN399_21150	COG0517	IMP dehydrogenase activity
DN399_21165	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DN399_21170	COG0295	cytidine deaminase activity
DN399_21175	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DN399_21185	COG1480	7TM receptor with intracellular HD hydrolase
DN399_21190	COG1702	phosphate starvation-inducible protein PhoH
DN399_21210	COG1610	YqeY-like protein
DN399_21225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DN399_21230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DN399_21260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN399_21265	COG1733	regulation of RNA biosynthetic process
DN399_21290	COG1466	dna polymerase III delta subunit
DN399_21300	COG2333	competence protein COMEC
DN399_21300	COG0658	competence protein
DN399_21305	COG2131	deaminase
DN399_21310	COG1555	photosystem II stabilization
DN399_21310	COG1596	polysaccharide export
DN399_21315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN399_21320	COG2226	methyltransferase
DN399_21325	COG0799	negative regulation of ribosome biogenesis
DN399_21330	COG1713	HD superfamily hydrolase involved in NAD metabolism
DN399_21340	COG1534	Rna-binding protein
DN399_21350	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DN399_21355	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DN399_21370	COG1191	sigma factor activity
DN399_21390	COG0778	Nitroreductase
DN399_21395	COG2357	RelA SpoT domain protein
DN399_21405	COG1785	Belongs to the alkaline phosphatase family
DN399_21415	COG2267	carboxylic ester hydrolase activity
DN399_21450	COG1404	Belongs to the peptidase S8 family
DN399_21455	COG3186	Phenylalanine-4-hydroxylase
DN399_21465	COG2514	catechol 2,3-dioxygenase activity
DN399_21470	COG2259	Doxx family
DN399_21510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN399_21525	COG1454	alcohol dehydrogenase
DN399_21525	COG1012	belongs to the aldehyde dehydrogenase family
DN399_21530	COG0626	cystathionine gamma-synthase activity
DN399_21535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN399_21560	COG0768	penicillin binding
DN399_21595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DN399_21625	COG0628	permease
DN399_21645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN399_21660	COG1104	cysteine desulfurase activity
DN399_21665	COG1959	2 iron, 2 sulfur cluster binding
DN399_21670	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DN399_21690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DN399_21710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN399_21720	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DN399_21720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DN399_21725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DN399_21730	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN399_21730	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN399_21740	COG2244	polysaccharide biosynthetic process
DN399_21745	COG2323	membrane
DN399_21755	COG1862	Preprotein translocase
DN399_21785	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DN399_21815	COG0157	Belongs to the NadC ModD family
DN399_21820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DN399_21825	COG1104	cysteine desulfurase activity
DN399_21830	COG1827	regulation of RNA biosynthetic process
DN399_21835	COG2258	MOSC domain
DN399_21840	COG0077	Prephenate dehydratase
DN399_21845	COG0577	efflux transmembrane transporter activity
DN399_21850	COG0577	efflux transmembrane transporter activity
DN399_21855	COG1136	(ABC) transporter
DN399_21860	COG5002	protein histidine kinase activity
DN399_21865	COG0745	RESPONSE REGULATOR receiver
DN399_21875	COG3290	protein histidine kinase activity
DN399_21885	COG2868	ribosomal protein
DN399_21895	COG1530	ribonuclease E activity
DN399_21900	COG1994	Peptidase M50
DN399_21905	COG0739	heme binding
DN399_21910	COG2894	cell division
DN399_21925	COG1792	Involved in formation and maintenance of cell shape
DN399_21930	COG1077	Cell shape determining protein MreB Mrl
DN399_21950	COG0285	dihydrofolate synthase activity
DN399_21965	COG1388	LysM domain
DN399_21975	COG0113	porphobilinogen synthase activity
DN399_21980	COG1587	Uroporphyrinogen-III synthase
DN399_21990	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN399_22000	COG1846	Transcriptional regulator
DN399_22005	COG1764	response to oxidative stress
DN399_22020	COG1067	ATP-dependent peptidase activity
DN399_22020	COG0470	DNA polymerase III
DN399_22065	COG0622	Phosphoesterase
DN399_22080	COG5401	PFAM Sporulation and spore germination
DN399_22095	COG2197	response regulator
DN399_22100	COG2233	PERMEase
DN399_22105	COG0402	S-adenosylhomocysteine deaminase activity
DN399_22110	COG1983	PspC domain protein
DN399_22115	COG1396	sequence-specific DNA binding
DN399_22120	COG0697	spore germination
DN399_22130	COG1959	2 iron, 2 sulfur cluster binding
DN399_22135	COG1668	transmembrane transport
DN399_22140	COG4152	abc transporter atp-binding protein
DN399_22145	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DN399_22150	COG1360	Flagellar Motor Protein
DN399_22155	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DN399_22165	COG1876	peptidase activity
DN399_22170	COG0824	Thioesterase
DN399_22175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DN399_22180	COG1053	succinate dehydrogenase
DN399_22185	COG2009	succinate dehydrogenase
DN399_22190	COG1719	4-vinyl reductase, 4VR
DN399_22200	COG3118	belongs to the thioredoxin family
DN399_22205	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DN399_22210	COG2086	electron transfer activity
DN399_22215	COG1024	Enoyl-CoA hydratase
DN399_22220	COG1309	transcriptional regulator
DN399_22225	COG0318	PFAM AMP-dependent synthetase and ligase
DN399_22255	COG2318	DinB family
DN399_22280	COG1131	(ABC) transporter
DN399_22285	COG2205	protein histidine kinase activity
DN399_22290	COG0745	RESPONSE REGULATOR receiver
DN399_22295	COG4895	conserved protein (DUF2196)
DN399_22300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DN399_22310	COG4509	Sortase family
DN399_22315	COG1120	ATPase activity
DN399_22330	COG5386	Cell surface protein
DN399_22340	COG5386	Cell surface protein
DN399_22345	COG1114	Component of the transport system for branched-chain amino acids
DN399_22350	COG1187	pseudouridine synthase activity
DN399_22360	COG1796	DNA polymerase
DN399_22360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
DN399_22365	COG1286	toxin biosynthetic process
DN399_22405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN399_22415	COG1418	mRNA catabolic process
DN399_22425	COG2814	Major facilitator Superfamily
DN399_22430	COG1566	PFAM secretion protein HlyD family protein
DN399_22435	COG1309	transcriptional regulator
DN399_22440	COG1363	Peptidase, m42
DN399_22465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DN399_22480	COG1484	DNA-dependent DNA replication
DN399_22485	COG3611	Membrane attachment protein
DN399_22495	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
DN399_22500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN399_22510	COG1971	Probably functions as a manganese efflux pump
DN399_22520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN399_22520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN399_22525	COG5002	protein histidine kinase activity
DN399_22530	COG0745	RESPONSE REGULATOR receiver
DN399_22550	COG0538	isocitrate dehydrogenase activity
DN399_22555	COG0372	Belongs to the citrate synthase family
DN399_22570	COG0628	permease
DN399_22575	COG3030	protein affecting phage T7 exclusion by the F plasmid
DN399_22600	COG1725	Transcriptional regulator
DN399_22605	COG0281	malic enzyme
DN399_22610	COG0587	DNA-directed DNA polymerase activity
DN399_22625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DN399_22640	COG4109	DRTGG domain
DN399_22650	COG0006	proline dipeptidase activity
DN399_22685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_22690	COG0662	Cupin 2, conserved barrel domain protein
DN399_22705	COG1028	Short-chain dehydrogenase reductase Sdr
DN399_22710	COG0589	response to stress
DN399_22750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_22775	COG0827	DNA restriction-modification system
DN399_22780	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DN399_22785	COG3874	Sporulation protein YtfJ
DN399_22800	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DN399_22810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN399_22825	COG1104	cysteine desulfurase activity
DN399_22835	COG0583	DNA-binding transcription factor activity
DN399_22840	COG0697	spore germination
DN399_22845	COG1309	transcriptional regulator
DN399_22850	COG1956	GAF domain-containing protein
DN399_22855	COG0626	cystathionine gamma-synthase activity
DN399_22885	COG0110	maltose O-acetyltransferase activity
DN399_22890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN399_22895	COG0454	-acetyltransferase
DN399_22900	COG0517	IMP dehydrogenase activity
DN399_22905	COG0123	including yeast histone deacetylase and acetoin utilization protein
DN399_22920	COG0745	RESPONSE REGULATOR receiver
DN399_22930	COG0666	response to abiotic stimulus
DN399_22965	COG1609	Transcriptional regulator
DN399_22970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DN399_22970	COG1605	Chorismate mutase
DN399_22975	COG4851	CamS sex pheromone cAM373 precursor
DN399_22980	COG3118	belongs to the thioredoxin family
DN399_22990	COG2309	aminopeptidase activity
DN399_23005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_23020	COG1674	ftsk spoiiie
DN399_23025	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN399_23025	COG1388	LysM domain
DN399_23035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN399_23045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN399_23050	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
DN399_23055	COG1363	Peptidase, m42
DN399_23065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_23080	COG0510	thiamine kinase activity
DN399_23085	COG1523	belongs to the glycosyl hydrolase 13 family
DN399_23095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DN399_23100	COG1349	DNA-binding transcription factor activity
DN399_23105	COG1187	pseudouridine synthase activity
DN399_23110	COG2244	polysaccharide biosynthetic process
DN399_23115	COG2081	HI0933 family
DN399_23120	COG2814	Major facilitator Superfamily
DN399_23130	COG3832	glyoxalase III activity
DN399_23155	COG1329	Transcriptional regulator
DN399_23180	COG0314	molybdopterin synthase activity
DN399_23185	COG1763	Mo-molybdopterin cofactor biosynthetic process
DN399_23190	COG0303	'Molybdopterin
DN399_23200	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN399_23205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN399_23230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN399_23240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN399_23280	COG2814	Major facilitator Superfamily
DN399_23285	COG0475	glutathione-regulated potassium exporter activity
DN399_23290	COG0490	domain, Protein
DN399_23295	COG0582	viral genome integration into host DNA
DN399_23305	COG1136	(ABC) transporter
DN399_23325	COG1242	4 iron, 4 sulfur cluster binding
DN399_23330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DN399_23355	COG2267	carboxylic ester hydrolase activity
DN399_23360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DN399_23365	COG0671	phosphoesterase, PA-phosphatase related
DN399_23370	COG0438	transferase activity, transferring glycosyl groups
DN399_23390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_23465	COG5002	protein histidine kinase activity
DN399_23470	COG3852	Histidine kinase
DN399_23485	COG2267	carboxylic ester hydrolase activity
DN399_23490	COG1368	sulfuric ester hydrolase activity
DN399_23505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN399_23510	COG1116	anion transmembrane transporter activity
DN399_23515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN399_23540	COG0494	nUDIX hydrolase
DN399_23585	COG0288	reversible hydration of carbon dioxide
DN399_23590	COG1271	oxidase subunit
DN399_23595	COG1294	oxidase, subunit
DN399_23610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_23635	COG1842	Phage shock protein A
DN399_23665	COG5002	protein histidine kinase activity
DN399_23670	COG0745	RESPONSE REGULATOR receiver
DN399_23700	COG1597	lipid kinase activity
DN399_23765	COG0586	Pfam SNARE associated Golgi protein
DN399_23775	COG0577	efflux transmembrane transporter activity
DN399_23780	COG1136	(ABC) transporter
DN399_23785	COG2207	Transcriptional regulator
DN399_23785	COG3708	Transcriptional regulator
DN399_23795	COG5658	integral membrane protein
DN399_23800	COG0640	Transcriptional regulator
DN399_23805	COG0745	RESPONSE REGULATOR receiver
DN399_23810	COG2205	protein histidine kinase activity
DN399_23815	COG0577	efflux transmembrane transporter activity
DN399_23820	COG0577	efflux transmembrane transporter activity
DN399_23825	COG1136	(ABC) transporter
DN399_23830	COG0577	efflux transmembrane transporter activity
DN399_23875	COG3964	amidohydrolase
DN399_23895	COG4948	Mandelate Racemase Muconate Lactonizing
DN399_23905	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DN399_23910	COG0596	Alpha beta hydrolase
DN399_23920	COG1169	isochorismate synthase
DN399_23925	COG1575	Belongs to the MenA family. Type 1 subfamily
DN399_23930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DN399_23935	COG1278	Cold shock
DN399_23950	COG0058	SHG alpha-glucan phosphorylase activity
DN399_23960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DN399_23980	COG1404	Belongs to the peptidase S8 family
DN399_23990	COG0039	L-malate dehydrogenase activity
DN399_23995	COG1309	transcriptional regulator
DN399_24095	COG0544	peptidyl-prolyl cis-trans isomerase activity
DN399_24130	COG1285	pathogenesis
DN399_24135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN399_24155	COG2155	Conserved Protein
DN399_24160	COG1098	S1 RNA binding domain
DN399_24165	COG0436	Aminotransferase
DN399_24170	COG1522	sequence-specific DNA binding
DN399_24175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN399_24180	COG2267	carboxylic ester hydrolase activity
DN399_24190	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DN399_24205	COG5018	Exonuclease
DN399_24210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN399_24225	COG0423	glycine-tRNA ligase activity
DN399_24230	COG2050	protein possibly involved in aromatic compounds catabolism
DN399_24240	COG1268	BioY protein
DN399_24245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN399_24250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DN399_24270	COG2076	Multidrug Resistance protein
DN399_24275	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DN399_24285	COG3584	3D domain protein
DN399_24300	COG1252	NADH dehydrogenase
DN399_24315	COG3708	Transcriptional regulator
DN399_24330	COG1683	Conserved Protein
DN399_24350	COG0316	Belongs to the HesB IscA family
DN399_24365	COG1252	NADH dehydrogenase
DN399_24375	COG2274	protein secretion by the type I secretion system
DN399_24380	COG0390	transport system, permease component
DN399_24385	COG2824	Alkylphosphonate utilization operon protein PhnA
DN399_24435	COG4837	Protein of unknown function (DUF1462)
DN399_24440	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DN399_24450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN399_24455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DN399_24475	COG1358	cellular component organization or biogenesis
DN399_24490	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN399_24495	COG0647	UMP catabolic process
DN399_24505	COG2445	Protein of unknown function DUF86
DN399_24510	COG1494	fructose-1,6-bisphosphatase
DN399_24535	COG4470	Protein conserved in bacteria
DN399_24545	COG0789	Transcriptional regulator
DN399_24550	COG4377	Putative membrane peptidase family (DUF2324)
DN399_24575	COG0739	heme binding
DN399_24585	COG3377	Domain of unknown function (DUF1805)
DN399_24590	COG0737	Belongs to the 5'-nucleotidase family
DN399_24600	COG0719	Fe-S assembly protein
DN399_24605	COG0822	iron-sulfur transferase activity
DN399_24610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DN399_24615	COG0719	Fe-S assembly protein
DN399_24620	COG0396	ATPase activity
DN399_24625	COG1464	Belongs to the NlpA lipoprotein family
DN399_24630	COG1464	Belongs to the NlpA lipoprotein family
DN399_24635	COG2011	ABC-type metal ion transport system permease component
DN399_24640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DN399_24650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN399_24655	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DN399_24665	COG1393	Belongs to the ArsC family
DN399_24705	COG1309	transcriptional regulator
DN399_24710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN399_24715	COG1960	acyl-CoA dehydrogenase activity
DN399_24720	COG0183	Belongs to the thiolase family
DN399_24725	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN399_24725	COG1024	Enoyl-CoA hydratase
DN399_24735	COG1686	Belongs to the peptidase S11 family
DN399_24750	COG0011	TIGRFAM Protein of
DN399_24755	COG0840	transmembrane signaling receptor activity
DN399_24765	COG2814	Major facilitator Superfamily
DN399_24770	COG0531	amino acid
DN399_24795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DN399_24835	COG0586	Pfam SNARE associated Golgi protein
DN399_24845	COG1376	ErfK ybiS ycfS ynhG family protein
DN399_24850	COG0745	RESPONSE REGULATOR receiver
DN399_24855	COG5002	protein histidine kinase activity
DN399_24885	COG0840	transmembrane signaling receptor activity
DN399_24890	COG2151	metal-sulfur cluster biosynthetic enzyme
DN399_24895	COG3227	Zinc metalloprotease (Elastase)
DN399_24915	COG0586	Pfam SNARE associated Golgi protein
DN399_24920	COG0475	glutathione-regulated potassium exporter activity
DN399_24925	COG0490	domain, Protein
DN399_24930	COG1115	amino acid carrier protein
DN399_24935	COG0783	Belongs to the Dps family
DN399_24960	COG1611	Belongs to the LOG family
DN399_24970	COG1528	Iron-storage protein
DN399_24980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN399_24985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN399_24990	COG1115	amino acid carrier protein
DN399_24995	COG1115	amino acid carrier protein
DN399_25000	COG2910	NAD(P)H-binding
DN399_25015	COG0656	L-ascorbic acid biosynthetic process
DN399_25020	COG2814	Major facilitator Superfamily
DN399_25025	COG1733	regulation of RNA biosynthetic process
DN399_25035	COG1252	NADH dehydrogenase
DN399_25055	COG3290	protein histidine kinase activity
DN399_25055	COG0840	transmembrane signaling receptor activity
DN399_25085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN399_25090	COG3223	Belongs to the PsiE family
DN399_25175	COG5002	protein histidine kinase activity
DN399_25180	COG0745	RESPONSE REGULATOR receiver
DN399_25185	COG1136	(ABC) transporter
DN399_25205	COG1136	(ABC) transporter
DN399_25240	COG0557	exoribonuclease II activity
DN399_25245	COG1647	Serine aminopeptidase, S33
DN399_25250	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN399_25255	COG1346	cytolysis
DN399_25290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN399_25305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DN399_25330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN399_25345	COG2323	membrane
DN399_25355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN399_25365	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DN399_25375	COG1051	belongs to the nudix hydrolase family
DN399_25385	COG0492	ferredoxin-NADP+ reductase activity
DN399_25390	COG0457	Tetratricopeptide repeat
DN399_25395	COG0110	maltose O-acetyltransferase activity
DN399_25415	COG1950	PFAM Membrane protein of
DN399_25425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN399_25430	COG0556	nucleotide-excision repair
DN399_25445	COG0789	Transcriptional regulator
DN399_25465	COG0583	DNA-binding transcription factor activity
DN399_25475	COG0655	NAD(P)H dehydrogenase (quinone) activity
DN399_25490	COG1132	(ABC) transporter
DN399_25495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN399_25500	COG0793	Belongs to the peptidase S41A family
DN399_25500	COG3409	Peptidoglycan-binding domain 1 protein
DN399_25505	COG2177	Part of the ABC transporter FtsEX involved in
DN399_25510	COG2884	Cell division ATP-binding protein ftsE
DN399_25535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DN399_25540	COG1278	Cold shock
DN399_25545	COG1040	competence protein
DN399_25550	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DN399_25555	COG0791	NLP P60 protein
DN399_25555	COG1388	LysM domain
DN399_25560	COG1733	regulation of RNA biosynthetic process
DN399_25565	COG1307	EDD domain protein, DegV family
DN399_25570	COG1739	Uncharacterized protein family UPF0029
DN399_25575	COG1316	TRANSCRIPTIONal
DN399_25580	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DN399_25585	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DN399_25590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN399_25600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DN399_25600	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DN399_25620	COG1486	melibiose metabolic process
DN399_25625	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN399_25630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN399_25650	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN399_25660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN399_25665	COG1301	dicarboxylic acid transport
DN399_25680	COG1511	domain protein
DN399_25685	COG0583	DNA-binding transcription factor activity
DN399_25690	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
DN399_25695	COG1271	oxidase subunit
DN399_25700	COG1294	oxidase, subunit
DN399_25705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN399_25735	COG1620	l-lactate permease
DN399_25745	COG2389	metal-binding protein
DN399_25760	COG1368	sulfuric ester hydrolase activity
DN399_25770	COG1388	LysM domain
DN399_25770	COG0791	NLP P60 protein
DN399_25775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN399_25785	COG1215	transferase activity, transferring glycosyl groups
DN399_25790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN399_25800	COG1388	LysM domain
DN399_25800	COG3584	3D domain protein
DN399_25830	COG4715	Zinc finger, swim domain protein
DN399_25835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DN399_25865	COG1191	sigma factor activity
DN399_25875	COG0577	efflux transmembrane transporter activity
DN399_25880	COG1136	(ABC) transporter
DN399_25900	COG2271	Major facilitator Superfamily
DN399_25915	COG5002	protein histidine kinase activity
DN399_25920	COG0745	RESPONSE REGULATOR receiver
DN399_25940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
DN399_25945	COG1215	transferase activity, transferring glycosyl groups
DN399_25965	COG0438	transferase activity, transferring glycosyl groups
DN399_25970	COG0438	transferase activity, transferring glycosyl groups
DN399_25975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DN399_25985	COG1086	Polysaccharide biosynthesis protein
DN399_25995	COG1045	serine acetyltransferase
DN399_26000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN399_26005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN399_26010	COG1086	Polysaccharide biosynthesis protein
DN399_26015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN399_26020	COG4464	protein tyrosine phosphatase activity
DN399_26025	COG0489	protein tyrosine kinase activity
DN399_26030	COG3944	biosynthesis protein
DN399_26035	COG0489	protein tyrosine kinase activity
DN399_26050	COG1609	Transcriptional regulator
DN399_26060	COG0739	heme binding
DN399_26075	COG3279	Response regulator of the LytR AlgR family
DN399_26080	COG2385	sporulation resulting in formation of a cellular spore
DN399_26095	COG4836	Membrane
DN399_26100	COG1007	ATP synthesis coupled electron transport
DN399_26105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN399_26110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN399_26120	COG0839	Belongs to the complex I subunit 6 family
DN399_26140	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN399_26155	COG3300	MHYT domain
DN399_26155	COG5001	Diguanylate cyclase
DN399_26205	COG0356	it plays a direct role in the translocation of protons across the membrane
DN399_26240	COG0698	ribose 5-phosphate isomerase
DN399_26255	COG2259	Doxx family
DN399_26260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN399_26275	COG0009	L-threonylcarbamoyladenylate synthase
DN399_26315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DN399_26320	COG1494	fructose-1,6-bisphosphatase
DN399_26340	COG4821	SIS domain
DN399_26350	COG3343	RNA polymerase activity
DN399_26360	COG1960	acyl-CoA dehydrogenase activity
DN399_26365	COG1960	acyl-CoA dehydrogenase activity
DN399_26370	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN399_26375	COG0183	Belongs to the thiolase family
DN399_26380	COG2181	nitrate reductase activity
DN399_26380	COG0247	lactate metabolic process
DN399_26385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN399_26395	COG5001	Diguanylate cyclase
DN399_26395	COG3300	MHYT domain
DN399_26410	COG3227	Zinc metalloprotease (Elastase)
DN399_26415	COG2197	response regulator
DN399_26420	COG4585	Histidine kinase
DN399_26425	COG0842	Transport permease protein
DN399_26430	COG1131	(ABC) transporter
DN399_26435	COG0024	Methionine aminopeptidase
DN399_26445	COG2234	aminopeptidase activity
DN399_26470	COG4506	Protein conserved in bacteria
DN399_26475	COG1619	proteins homologs of microcin C7 resistance protein MccF
DN399_26495	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DN399_26500	COG2814	Major facilitator Superfamily
DN399_26505	COG0789	Transcriptional regulator
DN399_26510	COG0584	glycerophosphoryl diester phosphodiesterase
DN399_26515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN399_26525	COG1994	Peptidase M50
DN399_26535	COG1078	dGTPase activity
DN399_26540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN399_26545	COG1120	ATPase activity
DN399_26550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_26555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN399_26575	COG0280	phosphate acetyltransferase
DN399_26590	COG3773	Cell wall hydrolase
DN399_26600	COG2363	Small membrane protein
DN399_26610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN399_26615	COG2233	PERMEase
DN399_26620	COG0561	phosphatase activity
DN399_26625	COG2814	Major facilitator Superfamily
DN399_26635	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
DN399_26640	COG1131	(ABC) transporter
DN399_26645	COG2755	lipolytic protein G-D-S-L family
DN399_26650	COG1609	Transcriptional regulator
DN399_26660	COG0460	homoserine dehydrogenase
DN399_26680	COG1011	Hydrolase
DN399_26685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN399_26695	COG2197	response regulator
DN399_26700	COG2203	Gaf domain
DN399_26700	COG4585	Histidine kinase
DN399_26705	COG0351	phosphomethylpyrimidine kinase
DN399_26710	COG3706	GGDEF domain
DN399_26715	COG2879	small protein
DN399_26720	COG1966	Carbon starvation protein
DN399_26725	COG3279	Response regulator of the LytR AlgR family
DN399_26730	COG0477	Major facilitator Superfamily
DN399_26745	COG0438	transferase activity, transferring glycosyl groups
DN399_26760	COG0840	transmembrane signaling receptor activity
DN399_26770	COG1607	acyl-coa hydrolase
DN399_26780	COG1216	Glycosyl transferase, family 2
DN399_26795	COG0463	Glycosyl transferase, family 2
DN399_26800	COG0488	(ABC) transporter
DN399_26805	COG1309	transcriptional regulator
DN399_26810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN399_26815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN399_26815	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DN399_26820	COG0628	permease
DN399_26840	COG3275	phosphorelay sensor kinase activity
DN399_26845	COG2814	Major facilitator Superfamily
DN399_26850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN399_26855	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
DN399_26885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DN399_26890	COG1272	protein, Hemolysin III
DN399_26910	COG1164	Oligoendopeptidase f
DN399_26920	COG5002	protein histidine kinase activity
DN399_26935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN399_26940	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DN399_26945	COG4853	Protein conserved in bacteria
DN399_26955	COG5002	protein histidine kinase activity
DN399_26960	COG0745	RESPONSE REGULATOR receiver
DN399_26990	COG0305	Participates in initiation and elongation during chromosome replication
DN399_27000	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
DN399_27005	COG4241	membrane
DN399_27025	COG0012	GTP binding
DN399_27030	COG4481	Protein conserved in bacteria
DN399_27035	COG0668	transmembrane transport
DN399_27045	COG1475	DNA binding
DN399_27050	COG1192	Involved in chromosome partitioning
DN399_27075	COG1847	R3H domain protein
DN399_27125	COG0457	Tetratricopeptide repeat
DN399_27310	COG0741	lytic transglycosylase activity
DN399_27310	COG0791	NLP P60 protein
DN399_27380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN399_27380	COG0551	DNA topoisomerase type I activity
DN399_27410	COG1104	cysteine desulfurase activity
DN399_27430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DN399_27465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DN399_27520	COG0653	protein targeting
DN399_27535	COG4166	transmembrane transport
DN399_27565	COG0791	NLP P60 protein
DN399_27565	COG1388	LysM domain
DN399_27565	COG3103	Sh3 type 3 domain protein
DN399_27575	COG1522	sequence-specific DNA binding
DN399_27580	COG5632	N-Acetylmuramoyl-L-alanine amidase
DN399_27580	COG3409	Peptidoglycan-binding domain 1 protein
DN399_27595	COG0456	acetyltransferase
DN399_27730	COG1760	l-serine dehydratase
DN399_27740	COG0156	8-amino-7-oxononanoate synthase activity
DN399_27865	COG0791	NLP P60 protein
DN399_27865	COG0741	lytic transglycosylase activity
DN399_27895	COG0551	DNA topoisomerase type I activity
DN399_27895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN399_27905	COG5002	protein histidine kinase activity
DN399_27935	COG1192	Involved in chromosome partitioning