locus-tag	class	description
NR984_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NR984_00010	COG0592	DNA-directed DNA polymerase activity
NR984_00015	COG2501	S4 domain
NR984_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NR984_00030	COG0187	DNA topoisomerase II activity
NR984_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NR984_00070	COG0516	GMP reductase activity
NR984_00070	COG0517	IMP dehydrogenase activity
NR984_00075	COG1686	Belongs to the peptidase S11 family
NR984_00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NR984_00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NR984_00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NR984_00095	COG1929	Belongs to the glycerate kinase type-1 family
NR984_00100	COG2610	gluconate transmembrane transporter activity
NR984_00105	COG3835	regulator
NR984_00120	COG1428	Deoxynucleoside kinase
NR984_00125	COG1428	Deoxynucleoside kinase
NR984_00130	COG1388	LysM domain
NR984_00130	COG3858	chitin binding
NR984_00135	COG1335	isochorismatase
NR984_00140	COG0590	tRNA wobble adenosine to inosine editing
NR984_00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NR984_00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NR984_00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NR984_00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
NR984_00210	COG3853	Toxic anion resistance protein (TelA)
NR984_00215	COG1982	Orn Lys Arg decarboxylase major
NR984_00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NR984_00225	COG3870	Protein conserved in bacteria
NR984_00230	COG1728	Protein conserved in bacteria
NR984_00235	COG0470	DNA polymerase III
NR984_00240	COG1774	PSP1 C-terminal conserved region
NR984_00245	COG4467	Involved in initiation control of chromosome replication
NR984_00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NR984_00255	COG2827	Endonuclease containing a URI domain
NR984_00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NR984_00265	COG2002	toxin-antitoxin pair type II binding
NR984_00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NR984_00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NR984_00275	COG0084	hydrolase, TatD family'
NR984_00280	COG3583	domain protein
NR984_00280	COG3584	3D domain protein
NR984_00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NR984_00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NR984_00300	COG4466	Protein conserved in bacteria
NR984_00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NR984_00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NR984_00320	COG0251	oxidation-reduction process
NR984_00325	COG2088	sporulation resulting in formation of a cellular spore
NR984_00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NR984_00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NR984_00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NR984_00345	COG0193	aminoacyl-tRNA hydrolase activity
NR984_00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NR984_00360	COG2002	toxin-antitoxin pair type II binding
NR984_00365	COG2244	polysaccharide biosynthetic process
NR984_00370	COG3956	TIGRFAM MazG family protein
NR984_00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NR984_00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NR984_00395	COG1098	S1 RNA binding domain
NR984_00410	COG2208	phosphoserine phosphatase activity
NR984_00415	COG2304	oxidoreductase activity
NR984_00420	COG0515	serine threonine protein kinase
NR984_00425	COG0037	tRNA processing
NR984_00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NR984_00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NR984_00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NR984_00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NR984_00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NR984_00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NR984_00460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NR984_00465	COG0512	Glutamine amidotransferase of anthranilate synthase
NR984_00470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NR984_00475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NR984_00480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NR984_00485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NR984_00490	COG1396	sequence-specific DNA binding
NR984_00495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NR984_00500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NR984_00580	COG4463	regulation of RNA biosynthetic process
NR984_00585	COG3880	PFAM UvrB UvrC protein
NR984_00590	COG3869	Catalyzes the specific phosphorylation of arginine residues in
NR984_00595	COG0542	response to heat
NR984_00600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NR984_00605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NR984_00610	COG4956	integral membrane protein (PIN domain superfamily)
NR984_00615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NR984_00620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NR984_00625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NR984_00630	COG1045	serine acetyltransferase
NR984_00635	COG0215	cysteine-tRNA ligase activity
NR984_00645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NR984_00650	COG3688	RNA-binding protein containing a PIN domain
NR984_00660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NR984_00670	COG0250	Participates in transcription elongation, termination and antitermination
NR984_00675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NR984_00680	COG0081	regulation of translation
NR984_00685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NR984_00690	COG0222	ribosome binding
NR984_00695	COG2813	Specifically methylates the guanine in position
NR984_00700	COG0085	RNA polymerase activity
NR984_00705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NR984_00710	COG1358	cellular component organization or biogenesis
NR984_00715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NR984_00720	COG0049	tRNA binding
NR984_00725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NR984_00730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NR984_00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NR984_00745	COG0088	Forms part of the polypeptide exit tunnel
NR984_00750	COG0089	rRNA binding
NR984_00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NR984_00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NR984_00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NR984_00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NR984_00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NR984_00780	COG0255	Belongs to the universal ribosomal protein uL29 family
NR984_00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NR984_00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NR984_00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NR984_00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NR984_00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NR984_00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NR984_00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NR984_00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NR984_00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NR984_00830	COG1841	ribosomal large subunit assembly
NR984_00835	COG0200	Binds to the 23S rRNA
NR984_00840	COG0201	protein transport
NR984_00845	COG0563	adenylate kinase activity
NR984_00850	COG0024	Methionine aminopeptidase
NR984_00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
NR984_00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NR984_00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NR984_00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NR984_00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NR984_00880	COG0202	RNA polymerase activity
NR984_00885	COG0203	ribosomal protein L17
NR984_00890	COG1122	ATPase activity
NR984_00895	COG1122	ATPase activity
NR984_00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NR984_00905	COG0101	tRNA pseudouridine synthase activity
NR984_00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NR984_00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NR984_00920	COG2318	DinB family
NR984_00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
NR984_00935	COG0489	protein tyrosine kinase activity
NR984_00945	COG2194	sulfuric ester hydrolase activity
NR984_00950	COG0726	polysaccharide deacetylase
NR984_00980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NR984_00990	COG0385	Bile acid
NR984_01005	COG3876	Protein conserved in bacteria
NR984_01010	COG1472	Belongs to the glycosyl hydrolase 3 family
NR984_01015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NR984_01020	COG1263	PTS System
NR984_01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_01025	COG1737	Transcriptional regulator
NR984_01030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NR984_01035	COG1683	Conserved Protein
NR984_01070	COG1595	DNA-templated transcription, initiation
NR984_01075	COG5662	AntiSigma factor
NR984_01080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NR984_01085	COG4856	YbbR-like protein
NR984_01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NR984_01095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NR984_01115	COG1725	Transcriptional regulator
NR984_01120	COG0640	Transcriptional regulator
NR984_01125	COG2814	Major facilitator Superfamily
NR984_01140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NR984_01165	COG1011	Hydrolase
NR984_01170	COG1113	amino acid transport
NR984_01175	COG2851	Citrate transporter
NR984_01180	COG3181	Tripartite tricarboxylate transporter family receptor
NR984_01185	COG4565	transcriptional regulatory protein
NR984_01200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NR984_01205	COG2211	Major facilitator Superfamily
NR984_01225	COG1331	Highly conserved protein containing a thioredoxin domain
NR984_01230	COG1331	Highly conserved protein containing a thioredoxin domain
NR984_01235	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NR984_01250	COG3220	belongs to the UPF0276 family
NR984_01270	COG1331	Highly conserved protein containing a thioredoxin domain
NR984_01280	COG0477	Major facilitator Superfamily
NR984_01300	COG1283	sodium-dependent phosphate transmembrane transporter activity
NR984_01305	COG4682	membrane
NR984_01325	COG0697	spore germination
NR984_01350	COG0371	Dehydrogenase
NR984_01355	COG0840	transmembrane signaling receptor activity
NR984_01360	COG4213	ABC transporter substrate-binding protein
NR984_01375	COG4257	antibiotic catabolic process
NR984_01385	COG0833	amino acid
NR984_01390	COG2040	homocysteine
NR984_01400	COG1263	PTS System
NR984_01400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_01400	COG2190	(PTS) system
NR984_01405	COG0789	Transcriptional regulator
NR984_01410	COG2323	membrane
NR984_01415	COG4451	ribulose bisphosphate carboxylase, small
NR984_01415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NR984_01420	COG2205	protein histidine kinase activity
NR984_01425	COG1115	amino acid carrier protein
NR984_01430	COG2066	Belongs to the glutaminase family
NR984_01440	COG4191	Histidine kinase
NR984_01445	COG0784	Response regulator, receiver
NR984_01475	COG3540	Alkaline phosphatase
NR984_01480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NR984_01485	COG0805	protein transport
NR984_01490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NR984_01495	COG1012	belongs to the aldehyde dehydrogenase family
NR984_01500	COG2271	Major facilitator Superfamily
NR984_01505	COG4948	Mandelate Racemase Muconate Lactonizing
NR984_01510	COG2186	Transcriptional regulator
NR984_01515	COG2721	sulfolactate sulfo-lyase activity
NR984_01520	COG0745	RESPONSE REGULATOR receiver
NR984_01525	COG2205	protein histidine kinase activity
NR984_01530	COG1131	(ABC) transporter
NR984_01555	COG3173	Aminoglycoside phosphotransferase
NR984_01560	COG1846	Transcriptional regulator
NR984_01565	COG0318	PFAM AMP-dependent synthetase and ligase
NR984_01585	COG0789	Transcriptional regulator
NR984_01610	COG0697	spore germination
NR984_01615	COG1714	RDD family
NR984_01620	COG1405	negative regulation of cell septum assembly
NR984_01620	COG3012	SEC-C Motif Domain Protein
NR984_01625	COG1131	(ABC) transporter
NR984_01650	COG0583	DNA-binding transcription factor activity
NR984_01655	COG1942	4-Oxalocrotonate Tautomerase
NR984_01660	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_01675	COG1288	antiporter activity
NR984_01685	COG0456	acetyltransferase
NR984_01695	COG1164	Oligoendopeptidase f
NR984_01700	COG2261	transglycosylase associated protein
NR984_01710	COG0247	lactate metabolic process
NR984_01715	COG0277	FAD linked oxidase domain protein
NR984_01725	COG1447	Phosphotransferase system cellobiose-specific component IIA
NR984_01730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NR984_01735	COG1486	melibiose metabolic process
NR984_01740	COG2188	Transcriptional regulator
NR984_01745	COG3394	polysaccharide catabolic process
NR984_01765	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_01775	COG1595	DNA-templated transcription, initiation
NR984_01785	COG3773	Cell wall hydrolase
NR984_01790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NR984_01795	COG0791	NLP P60 protein
NR984_01795	COG3883	PFAM NLP P60 protein
NR984_01810	COG1309	transcriptional regulator
NR984_01830	COG2310	stress, protein
NR984_01835	COG2310	stress, protein
NR984_01840	COG2310	stress, protein
NR984_01845	COG0861	Integral membrane protein TerC family
NR984_01865	COG3853	Toxic anion resistance protein (TelA)
NR984_01870	COG0785	Cytochrome C biogenesis protein
NR984_01880	COG0789	Transcriptional regulator
NR984_01885	COG2223	nitrite transmembrane transporter activity
NR984_01890	COG0039	L-malate dehydrogenase activity
NR984_01895	COG1620	l-lactate permease
NR984_01900	COG1280	lysine exporter protein (LysE YggA)
NR984_01905	COG1113	amino acid transport
NR984_01910	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NR984_01915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NR984_01920	COG3541	Predicted nucleotidyltransferase
NR984_01925	COG0506	proline dehydrogenase activity
NR984_01930	COG1012	belongs to the aldehyde dehydrogenase family
NR984_01935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NR984_01940	COG2508	Transcriptional regulator
NR984_01945	COG3689	TIGRFAM TIGR03943 family protein
NR984_01950	COG0701	Predicted permease
NR984_01955	COG3458	cephalosporin-C deacetylase activity
NR984_01975	COG0765	amino acid transport
NR984_01980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NR984_01985	COG2249	NAD(P)H dehydrogenase (quinone) activity
NR984_01995	COG2723	6-phospho-beta-galactosidase activity
NR984_02005	COG3209	COG3209 Rhs family protein
NR984_02015	COG0515	serine threonine protein kinase
NR984_02015	COG3266	domain, Protein
NR984_02025	COG5444	nuclease activity
NR984_02050	COG1176	ABC-type spermidine putrescine transport system, permease component I
NR984_02055	COG1177	transmembrane transport
NR984_02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NR984_02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NR984_02070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NR984_02075	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NR984_02080	COG0697	spore germination
NR984_02085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NR984_02095	COG2819	hydrolase of the alpha beta superfamily
NR984_02110	COG2364	Membrane
NR984_02120	COG1131	(ABC) transporter
NR984_02150	COG1126	abc transporter atp-binding protein
NR984_02155	COG0765	amino acid transport
NR984_02160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NR984_02165	COG3829	transcription factor binding
NR984_02170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NR984_02175	COG0833	amino acid
NR984_02180	COG0010	Belongs to the arginase family
NR984_02185	COG0583	DNA-binding transcription factor activity
NR984_02190	COG0163	prenyltransferase activity
NR984_02195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NR984_02240	COG5444	nuclease activity
NR984_02260	COG2972	Histidine kinase
NR984_02265	COG4753	response regulator
NR984_02265	COG2207	Transcriptional regulator
NR984_02270	COG4213	ABC transporter substrate-binding protein
NR984_02280	COG4214	carbohydrate transport
NR984_02285	COG2271	Major facilitator Superfamily
NR984_02290	COG0456	acetyltransferase
NR984_02290	COG1846	Transcriptional regulator
NR984_02295	COG1874	Beta-galactosidase
NR984_02300	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
NR984_02305	COG3104	oligopeptide transport
NR984_02310	COG5434	Belongs to the glycosyl hydrolase 28 family
NR984_02320	COG0697	spore germination
NR984_02330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NR984_02335	COG0789	Transcriptional regulator
NR984_02340	COG1136	(ABC) transporter
NR984_02345	COG0577	efflux transmembrane transporter activity
NR984_02350	COG0745	RESPONSE REGULATOR receiver
NR984_02355	COG3850	Histidine kinase
NR984_02355	COG5002	protein histidine kinase activity
NR984_02360	COG0840	transmembrane signaling receptor activity
NR984_02360	COG3290	protein histidine kinase activity
NR984_02375	COG0527	aspartate kinase activity
NR984_02380	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_02385	COG4605	iron ion homeostasis
NR984_02390	COG4604	ABC transporter, ATP-binding protein
NR984_02395	COG4607	ABC-type enterochelin transport system periplasmic component
NR984_02400	COG2814	Major facilitator Superfamily
NR984_02405	COG1309	transcriptional regulator
NR984_02415	COG0778	Nitroreductase
NR984_02420	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NR984_02425	COG0640	Transcriptional regulator
NR984_02430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NR984_02435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NR984_02440	COG0531	amino acid
NR984_02445	COG1012	belongs to the aldehyde dehydrogenase family
NR984_02460	COG4549	nuclear export factor GLE1
NR984_02465	COG1276	copper resistance
NR984_02465	COG2372	response to copper ion
NR984_02470	COG1349	DNA-binding transcription factor activity
NR984_02475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NR984_02480	COG0243	molybdopterin cofactor binding
NR984_02485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NR984_02490	COG2146	nitrite reductase [NAD(P)H] activity
NR984_02495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NR984_02495	COG1587	Uroporphyrinogen-III synthase
NR984_02500	COG1802	Transcriptional regulator
NR984_02505	COG0471	metal ion transport
NR984_02520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_02535	COG3959	Transketolase, thiamine diphosphate binding domain
NR984_02540	COG3958	Transketolase
NR984_02545	COG0561	phosphatase activity
NR984_02550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NR984_02555	COG1914	H( )-stimulated, divalent metal cation uptake system
NR984_02560	COG4336	lyase activity
NR984_02565	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NR984_02570	COG1984	allophanate hydrolase subunit 2
NR984_02575	COG1414	Transcriptional regulator
NR984_02580	COG2755	lipolytic protein G-D-S-L family
NR984_02585	COG2213	PTS system mannitol-specific
NR984_02590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_02595	COG0246	Mannitol dehydrogenase
NR984_02600	COG3711	transcriptional antiterminator
NR984_02605	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_02610	COG1917	Cupin 2, conserved barrel domain protein
NR984_02620	COG3871	stress protein (general stress protein 26)
NR984_02635	COG2814	Major facilitator Superfamily
NR984_02645	COG1522	sequence-specific DNA binding
NR984_02650	COG0551	DNA topoisomerase type I activity
NR984_02650	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NR984_02655	COG0531	amino acid
NR984_02665	COG0028	Belongs to the TPP enzyme family
NR984_02670	COG3397	chitin binding
NR984_02680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NR984_02685	COG1914	H( )-stimulated, divalent metal cation uptake system
NR984_02690	COG2261	transglycosylase associated protein
NR984_02695	COG1027	Aspartate ammonia-lyase
NR984_02705	COG4876	unkown
NR984_02710	COG2217	Heavy metal translocating P-type atpase
NR984_02720	COG0662	Cupin 2, conserved barrel domain protein
NR984_02725	COG3729	General stress protein
NR984_02730	COG0628	permease
NR984_02735	COG1301	dicarboxylic acid transport
NR984_02740	COG1131	(ABC) transporter
NR984_02745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NR984_02755	COG1960	acyl-CoA dehydrogenase activity
NR984_02770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_02775	COG1181	Belongs to the D-alanine--D-alanine ligase family
NR984_02780	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NR984_02790	COG0513	Belongs to the DEAD box helicase family
NR984_02795	COG3402	PFAM membrane-flanked domain
NR984_02800	COG3428	Bacterial PH domain
NR984_02805	COG0705	Rhomboid family
NR984_02810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NR984_02815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NR984_02820	COG0864	Transcriptional regulator
NR984_02825	COG2337	Toxic component of a toxin-antitoxin (TA) module
NR984_02830	COG1366	Belongs to the anti-sigma-factor antagonist family
NR984_02835	COG1366	Belongs to the anti-sigma-factor antagonist family
NR984_02840	COG2172	sigma factor antagonist activity
NR984_02845	COG2208	phosphoserine phosphatase activity
NR984_02855	COG2172	sigma factor antagonist activity
NR984_02860	COG1191	sigma factor activity
NR984_02865	COG2208	phosphoserine phosphatase activity
NR984_02870	COG2183	response to ionizing radiation
NR984_02875	COG1309	transcriptional regulator
NR984_02880	COG1033	growth of symbiont in host cell
NR984_02880	COG2409	Drug exporters of the RND superfamily
NR984_02890	COG3091	SprT-like family
NR984_02930	COG0697	spore germination
NR984_02945	COG1476	TRANSCRIPTIONal
NR984_02950	COG3239	Fatty acid desaturase
NR984_02955	COG1278	Cold shock
NR984_02960	COG1063	alcohol dehydrogenase
NR984_02965	COG2364	Membrane
NR984_02970	COG1846	Transcriptional regulator
NR984_02975	COG0456	acetyltransferase
NR984_02980	COG2808	Putative FMN-binding domain
NR984_02990	COG1733	regulation of RNA biosynthetic process
NR984_02995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NR984_03005	COG0583	DNA-binding transcription factor activity
NR984_03025	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NR984_03030	COG1113	amino acid transport
NR984_03045	COG1595	DNA-templated transcription, initiation
NR984_03055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NR984_03055	COG2755	lipolytic protein G-D-S-L family
NR984_03060	COG2814	Major facilitator Superfamily
NR984_03065	COG0745	RESPONSE REGULATOR receiver
NR984_03065	COG2972	Histidine kinase
NR984_03075	COG3279	Response regulator of the LytR AlgR family
NR984_03085	COG3764	Sortase (surface protein transpeptidase)
NR984_03090	COG2814	Major facilitator Superfamily
NR984_03130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NR984_03135	COG0802	atpase or kinase
NR984_03140	COG1214	PFAM Peptidase M22, glycoprotease
NR984_03145	COG0456	acetyltransferase
NR984_03150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NR984_03155	COG0488	(ABC) transporter
NR984_03160	COG0315	cyclic pyranopterin monophosphate synthase activity
NR984_03165	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NR984_03170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NR984_03175	COG0805	protein transport
NR984_03185	COG1266	CAAX protease self-immunity
NR984_03190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NR984_03195	COG0459	protein refolding
NR984_03210	COG2720	vancomycin resistance protein
NR984_03225	COG2135	peptidase activity
NR984_03235	COG1309	transcriptional regulator
NR984_03240	COG0574	Belongs to the PEP-utilizing enzyme family
NR984_03240	COG3848	Pyruvate phosphate dikinase
NR984_03250	COG3189	MarR family transcriptional regulator
NR984_03255	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
NR984_03260	COG2272	Belongs to the type-B carboxylesterase lipase family
NR984_03265	COG2814	Major facilitator Superfamily
NR984_03270	COG1842	Phage shock protein A
NR984_03275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NR984_03280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NR984_03285	COG4260	virion core protein, lumpy skin disease virus
NR984_03295	COG1378	Sugar-specific transcriptional regulator TrmB
NR984_03300	COG1280	lysine exporter protein (LysE YggA)
NR984_03305	COG3339	Conserved Protein
NR984_03310	COG0772	Belongs to the SEDS family
NR984_03315	COG0772	Belongs to the SEDS family
NR984_03335	COG0726	polysaccharide deacetylase
NR984_03345	COG1609	Transcriptional regulator
NR984_03350	COG0366	Alpha amylase catalytic
NR984_03355	COG2182	Extracellular solute-binding protein
NR984_03360	COG1175	transmembrane transport
NR984_03365	COG3833	ABC-type maltose transport systems, permease component
NR984_03370	COG5521	maltodextrose utilization protein MalA
NR984_03375	COG1554	hydrolase, family 65, central catalytic
NR984_03380	COG0366	Alpha amylase catalytic
NR984_03385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NR984_03390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NR984_03395	COG1846	Transcriptional regulator
NR984_03410	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NR984_03415	COG0823	Involved in the tonB-independent uptake of proteins
NR984_03445	COG0702	epimerase
NR984_03455	COG2132	Multicopper oxidase
NR984_03470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NR984_03475	COG0714	Associated with various cellular activities
NR984_03480	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
NR984_03485	COG1305	Transglutaminase-like
NR984_03490	COG0519	Catalyzes the synthesis of GMP from XMP
NR984_03490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NR984_03495	COG2252	PERMEase
NR984_03510	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
NR984_03520	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NR984_03525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NR984_03530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NR984_03535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NR984_03540	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NR984_03545	COG0047	phosphoribosylformylglycinamidine synthase activity
NR984_03550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NR984_03555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NR984_03560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NR984_03565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NR984_03570	COG0138	bifunctional purine biosynthesis protein purh
NR984_03575	COG0151	Belongs to the GarS family
NR984_03590	COG2124	cytochrome p450
NR984_03615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NR984_03620	COG1470	cell adhesion involved in biofilm formation
NR984_03625	COG4496	protein, YerC YecD
NR984_03630	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NR984_03635	COG0210	DNA helicase
NR984_03640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NR984_03645	COG4851	CamS sex pheromone cAM373 precursor
NR984_03650	COG2188	Transcriptional regulator
NR984_03670	COG1735	metal-dependent hydrolase with the TIM-barrel fold
NR984_03675	COG0626	cystathionine gamma-synthase activity
NR984_03680	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NR984_03685	COG3457	Alanine racemase
NR984_03690	COG0363	glucosamine-6-phosphate deaminase activity
NR984_03695	COG1285	pathogenesis
NR984_03700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NR984_03705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NR984_03710	COG0154	amidase activity
NR984_03715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NR984_03730	COG4124	Belongs to the glycosyl hydrolase 26 family
NR984_03735	COG1309	transcriptional regulator
NR984_03740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NR984_03750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NR984_03755	COG1957	nucleoside hydrolase
NR984_03760	COG1597	lipid kinase activity
NR984_03765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NR984_03815	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NR984_03840	COG1715	Restriction endonuclease
NR984_03860	COG2190	(PTS) system
NR984_03860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_03860	COG1263	PTS System
NR984_03865	COG2723	6-phospho-beta-galactosidase activity
NR984_03870	COG3711	transcriptional antiterminator
NR984_03875	COG0457	Tetratricopeptide repeat
NR984_03890	COG0217	transcriptional regulatory protein
NR984_03905	COG1012	belongs to the aldehyde dehydrogenase family
NR984_03910	COG0840	transmembrane signaling receptor activity
NR984_03915	COG0471	metal ion transport
NR984_03920	COG0488	(ABC) transporter
NR984_03930	COG1469	GTP cyclohydrolase I activity
NR984_03945	COG0523	cobalamin synthesis protein
NR984_03950	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NR984_03955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NR984_03960	COG0156	8-amino-7-oxononanoate synthase activity
NR984_03965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NR984_03970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NR984_03975	COG2124	cytochrome p450
NR984_03985	COG0789	Transcriptional regulator
NR984_03990	COG2814	Major facilitator Superfamily
NR984_03995	COG0488	(ABC) transporter
NR984_04000	COG0513	Belongs to the DEAD box helicase family
NR984_04005	COG2130	NADP-dependent
NR984_04020	COG0471	metal ion transport
NR984_04040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NR984_04050	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NR984_04055	COG5658	integral membrane protein
NR984_04060	COG0640	Transcriptional regulator
NR984_04065	COG1254	Belongs to the acylphosphatase family
NR984_04070	COG2258	MOSC domain
NR984_04085	COG0024	Methionine aminopeptidase
NR984_04090	COG1368	sulfuric ester hydrolase activity
NR984_04100	COG1115	amino acid carrier protein
NR984_04105	COG1263	PTS System
NR984_04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_04115	COG2188	Transcriptional regulator
NR984_04140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NR984_04145	COG1045	serine acetyltransferase
NR984_04150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NR984_04160	COG1215	transferase activity, transferring glycosyl groups
NR984_04165	COG0463	Glycosyl transferase, family 2
NR984_04165	COG0457	Tetratricopeptide repeat
NR984_04175	COG0673	inositol 2-dehydrogenase activity
NR984_04185	COG0657	acetylesterase activity
NR984_04190	COG1733	regulation of RNA biosynthetic process
NR984_04195	COG0778	Nitroreductase
NR984_04205	COG0693	protein deglycase activity
NR984_04210	COG4840	Belongs to the UPF0435 family
NR984_04215	COG1115	amino acid carrier protein
NR984_04220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NR984_04225	COG4980	gas vesicle protein
NR984_04230	COG1295	ribonuclease BN
NR984_04235	COG0477	Major facilitator Superfamily
NR984_04245	COG0387	Pfam Sodium calcium exchanger
NR984_04255	COG0535	radical SAM domain protein
NR984_04265	COG0726	polysaccharide deacetylase
NR984_04270	COG0371	Dehydrogenase
NR984_04280	COG0598	Magnesium transport protein CorA
NR984_04285	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NR984_04290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NR984_04295	COG4637	Psort location Cytoplasmic, score
NR984_04320	COG1819	glycosyl
NR984_04330	COG0477	Major facilitator Superfamily
NR984_04335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_04335	COG1263	PTS System
NR984_04340	COG3711	transcriptional antiterminator
NR984_04345	COG0288	reversible hydration of carbon dioxide
NR984_04350	COG3002	Belongs to the UPF0753 family
NR984_04355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NR984_04360	COG5609	conserved protein (DUF2294)
NR984_04370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NR984_04375	COG0022	dehydrogenase e1 component
NR984_04380	COG0508	dehydrogenase complex catalyzes the overall conversion of
NR984_04385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NR984_04390	COG3284	Transcriptional regulator
NR984_04395	COG1742	UPF0060 membrane protein
NR984_04400	COG1486	melibiose metabolic process
NR984_04405	COG1737	Transcriptional regulator
NR984_04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_04410	COG1263	PTS System
NR984_04425	COG1733	regulation of RNA biosynthetic process
NR984_04430	COG2259	Doxx family
NR984_04435	COG2514	catechol 2,3-dioxygenase activity
NR984_04445	COG3507	Belongs to the glycosyl hydrolase 43 family
NR984_04450	COG2207	Transcriptional regulator
NR984_04450	COG1917	Cupin 2, conserved barrel domain protein
NR984_04455	COG1653	transport
NR984_04460	COG2249	NAD(P)H dehydrogenase (quinone) activity
NR984_04465	COG1051	belongs to the nudix hydrolase family
NR984_04475	COG0392	lysyltransferase activity
NR984_04475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NR984_04480	COG0384	phenazine biosynthesis protein PhzF
NR984_04485	COG0778	Nitroreductase
NR984_04510	COG2137	regulation of response to DNA damage stimulus
NR984_04535	COG0463	Glycosyl transferase, family 2
NR984_04545	COG4485	Bacterial membrane protein, YfhO
NR984_04550	COG1988	membrane-bound metal-dependent
NR984_04555	COG1194	a g-specific adenine glycosylase
NR984_04565	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_04580	COG3557	Belongs to the UPF0374 family
NR984_04585	COG1132	(ABC) transporter
NR984_04590	COG0444	Belongs to the ABC transporter superfamily
NR984_04595	COG4608	Belongs to the ABC transporter superfamily
NR984_04600	COG0747	negative chemotaxis
NR984_04605	COG0601	transmembrane transport
NR984_04610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NR984_04615	COG4129	membrane
NR984_04620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NR984_04625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NR984_04630	COG0735	belongs to the Fur family
NR984_04735	COG4974	Belongs to the 'phage' integrase family
NR984_04880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NR984_04880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NR984_04915	COG1780	Probably involved in ribonucleotide reductase function
NR984_04920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NR984_04935	COG0756	dUTP diphosphatase activity
NR984_04945	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
NR984_04950	COG3584	3D domain protein
NR984_05005	COG1793	dna ligase
NR984_05070	COG0740	serine-type endopeptidase activity
NR984_05120	COG5280	Phage tail tape measure protein TP901
NR984_05120	COG3953	SLT domain
NR984_05160	COG1388	LysM domain
NR984_05160	COG3409	Peptidoglycan-binding domain 1 protein
NR984_05160	COG5632	N-Acetylmuramoyl-L-alanine amidase
NR984_05180	COG0438	transferase activity, transferring glycosyl groups
NR984_05200	COG0457	Tetratricopeptide repeat
NR984_05225	COG5444	nuclease activity
NR984_05240	COG5444	nuclease activity
NR984_05245	COG0457	Tetratricopeptide repeat
NR984_05250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NR984_05260	COG0710	3-dehydroquinate dehydratase activity
NR984_05265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NR984_05270	COG1116	anion transmembrane transporter activity
NR984_05275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NR984_05280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NR984_05285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NR984_05295	COG1476	TRANSCRIPTIONal
NR984_05305	COG1131	(ABC) transporter
NR984_05325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NR984_05335	COG3382	B3 4 domain protein
NR984_05340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NR984_05350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NR984_05355	COG0789	Transcriptional regulator
NR984_05360	COG1664	Polymer-forming cytoskeletal
NR984_05370	COG2766	serine protein kinase
NR984_05375	COG2718	Belongs to the UPF0229 family
NR984_05385	COG1566	PFAM secretion protein HlyD family protein
NR984_05390	COG2814	Major facilitator Superfamily
NR984_05395	COG0655	NAD(P)H dehydrogenase (quinone) activity
NR984_05405	COG1131	(ABC) transporter
NR984_05410	COG1131	(ABC) transporter
NR984_05415	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NR984_05420	COG1278	Cold shock
NR984_05425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NR984_05430	COG2011	ABC-type metal ion transport system permease component
NR984_05435	COG1464	Belongs to the NlpA lipoprotein family
NR984_05440	COG1823	symporter activity
NR984_05465	COG5577	PFAM Coat F domain
NR984_05470	COG5002	protein histidine kinase activity
NR984_05475	COG1525	nuclease
NR984_05475	COG4085	toxin activity
NR984_05475	COG0737	Belongs to the 5'-nucleotidase family
NR984_05480	COG3764	Sortase (surface protein transpeptidase)
NR984_05485	COG0564	pseudouridine synthase activity
NR984_05495	COG0517	IMP dehydrogenase activity
NR984_05500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NR984_05505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NR984_05505	COG3153	acetyltransferase
NR984_05510	COG0488	(ABC) transporter
NR984_05515	COG2116	formate transmembrane transporter activity
NR984_05520	COG0679	Auxin Efflux Carrier
NR984_05525	COG0604	alcohol dehydrogenase
NR984_05530	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NR984_05535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NR984_05540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NR984_05545	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NR984_05550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NR984_05565	COG4585	Histidine kinase
NR984_05565	COG2203	Gaf domain
NR984_05570	COG2197	response regulator
NR984_05575	COG0431	NADPH-dependent FMN reductase
NR984_05590	COG1959	2 iron, 2 sulfur cluster binding
NR984_05595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NR984_05595	COG1017	nitric oxide dioxygenase activity
NR984_05600	COG2719	SpoVR family
NR984_05605	COG0791	NLP P60 protein
NR984_05605	COG1388	LysM domain
NR984_05610	COG0583	DNA-binding transcription factor activity
NR984_05615	COG0372	Belongs to the citrate synthase family
NR984_05620	COG2133	pyrroloquinoline quinone binding
NR984_05625	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_05630	COG0733	neurotransmitter:sodium symporter activity
NR984_05640	COG2207	Transcriptional regulator
NR984_05640	COG3708	Transcriptional regulator
NR984_05645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NR984_05665	COG1595	DNA-templated transcription, initiation
NR984_05670	COG0662	Cupin 2, conserved barrel domain protein
NR984_05675	COG0204	Acyl-transferase
NR984_05680	COG3152	Membrane
NR984_05690	COG1309	transcriptional regulator
NR984_05695	COG1253	flavin adenine dinucleotide binding
NR984_05700	COG0789	Transcriptional regulator
NR984_05705	COG1253	flavin adenine dinucleotide binding
NR984_05725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NR984_05730	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NR984_05735	COG0584	glycerophosphoryl diester phosphodiesterase
NR984_05745	COG0668	transmembrane transport
NR984_05750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NR984_05760	COG0726	polysaccharide deacetylase
NR984_05770	COG1757	Na H antiporter
NR984_05775	COG2017	converts alpha-aldose to the beta-anomer
NR984_05800	COG0589	response to stress
NR984_05805	COG1132	(ABC) transporter
NR984_05810	COG1132	(ABC) transporter
NR984_05815	COG0702	epimerase
NR984_05835	COG3842	ATPase activity
NR984_05840	COG2508	Transcriptional regulator
NR984_05850	COG0189	ligase activity
NR984_05855	COG0189	ligase activity
NR984_05860	COG4399	Belongs to the UPF0754 family
NR984_05865	COG3679	Belongs to the UPF0342 family
NR984_05870	COG0561	phosphatase activity
NR984_05875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NR984_05880	COG0475	glutathione-regulated potassium exporter activity
NR984_05885	COG0490	domain, Protein
NR984_05895	COG1024	Enoyl-CoA hydratase
NR984_05900	COG0457	Tetratricopeptide repeat
NR984_05920	COG4152	abc transporter atp-binding protein
NR984_05925	COG1668	transmembrane transport
NR984_05930	COG0420	3'-5' exonuclease activity
NR984_05935	COG4717	serine-type aminopeptidase activity
NR984_05940	COG3481	metal-dependent phosphohydrolase, HD sub domain
NR984_05950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NR984_05980	COG1846	Transcriptional regulator
NR984_05985	COG4980	gas vesicle protein
NR984_06000	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NR984_06005	COG0537	adenosine 5'-monophosphoramidase activity
NR984_06010	COG1131	(ABC) transporter
NR984_06015	COG4473	ABC transporter
NR984_06025	COG1473	amidohydrolase
NR984_06030	COG3069	C4-dicarboxylate transmembrane transporter activity
NR984_06035	COG2329	Antibiotic biosynthesis monooxygenase
NR984_06040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NR984_06045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NR984_06050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NR984_06055	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NR984_06060	COG1309	transcriptional regulator
NR984_06065	COG1511	domain protein
NR984_06070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NR984_06075	COG1363	Peptidase, m42
NR984_06085	COG1301	dicarboxylic acid transport
NR984_06095	COG1234	tRNA 3'-trailer cleavage
NR984_06100	COG0095	Lipoate-protein ligase
NR984_06105	COG0318	PFAM AMP-dependent synthetase and ligase
NR984_06115	COG1396	sequence-specific DNA binding
NR984_06130	COG0501	Belongs to the peptidase M48B family
NR984_06140	COG0697	spore germination
NR984_06145	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NR984_06150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_06155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_06160	COG0406	alpha-ribazole phosphatase activity
NR984_06165	COG0840	transmembrane signaling receptor activity
NR984_06170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NR984_06170	COG0723	plastoquinol--plastocyanin reductase activity
NR984_06175	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_06185	COG4903	ComK protein
NR984_06195	COG0398	Pfam SNARE associated Golgi protein
NR984_06200	COG0681	Belongs to the peptidase S26 family
NR984_06205	COG1404	Belongs to the peptidase S8 family
NR984_06215	COG2508	Transcriptional regulator
NR984_06220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NR984_06225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NR984_06230	COG3257	ureidoglycine aminohydrolase activity
NR984_06235	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NR984_06240	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NR984_06245	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NR984_06250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NR984_06260	COG0549	Belongs to the carbamate kinase family
NR984_06265	COG2814	Major facilitator Superfamily
NR984_06275	COG0457	Tetratricopeptide repeat
NR984_06295	COG1609	Transcriptional regulator
NR984_06300	COG1653	transport
NR984_06305	COG1175	transmembrane transport
NR984_06310	COG0395	ABC-type sugar transport system, permease component
NR984_06315	COG1486	melibiose metabolic process
NR984_06320	COG3180	Ammonia monooxygenase
NR984_06335	COG3546	catalase activity
NR984_06340	COG0318	PFAM AMP-dependent synthetase and ligase
NR984_06345	COG2814	Major facilitator Superfamily
NR984_06345	COG0477	Major facilitator Superfamily
NR984_06355	COG5002	protein histidine kinase activity
NR984_06360	COG0745	RESPONSE REGULATOR receiver
NR984_06365	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NR984_06370	COG0725	ABC transporter, periplasmic molybdate-binding protein
NR984_06375	COG4149	molybdate abc transporter
NR984_06380	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NR984_06385	COG1074	ATP-dependent DNA helicase activity
NR984_06390	COG0420	3'-5' exonuclease activity
NR984_06395	COG0419	ATPase involved in DNA repair
NR984_06440	COG5337	Spore coat protein CotH
NR984_06450	COG0179	Fumarylacetoacetate (FAA) hydrolase
NR984_06470	COG0367	asparagine synthase
NR984_06475	COG0004	ammonium transporteR
NR984_06485	COG0534	Mate efflux family protein
NR984_06490	COG1917	Cupin 2, conserved barrel domain protein
NR984_06490	COG2207	Transcriptional regulator
NR984_06500	COG1609	Transcriptional regulator
NR984_06505	COG0673	inositol 2-dehydrogenase activity
NR984_06520	COG0076	glutamate decarboxylase activity
NR984_06545	COG2153	protein acetylation
NR984_06550	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_06555	COG2378	regulation of single-species biofilm formation
NR984_06560	COG0646	methionine synthase
NR984_06560	COG1410	methionine synthase
NR984_06565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NR984_06565	COG0646	methionine synthase
NR984_06570	COG1666	GTP binding
NR984_06575	COG2996	Protein conserved in bacteria
NR984_06590	COG1307	EDD domain protein, DegV family
NR984_06595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NR984_06605	COG0516	GMP reductase activity
NR984_06620	COG0561	phosphatase activity
NR984_06625	COG1073	alpha beta
NR984_06630	COG2151	metal-sulfur cluster biosynthetic enzyme
NR984_06635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NR984_06640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NR984_06645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NR984_06650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NR984_06655	COG0505	Belongs to the CarA family
NR984_06660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NR984_06665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NR984_06670	COG1968	undecaprenyl-diphosphatase activity
NR984_06685	COG2267	carboxylic ester hydrolase activity
NR984_06695	COG1744	ABC transporter substrate-binding protein PnrA-like
NR984_06710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NR984_06715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NR984_06720	COG5504	Zn-dependent protease
NR984_06725	COG0444	Belongs to the ABC transporter superfamily
NR984_06730	COG4608	Belongs to the ABC transporter superfamily
NR984_06740	COG0601	transmembrane transport
NR984_06745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NR984_06760	COG0180	Tryptophanyl-tRNA synthetase
NR984_06765	COG4166	transmembrane transport
NR984_06770	COG0601	transmembrane transport
NR984_06775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NR984_06780	COG0444	Belongs to the ABC transporter superfamily
NR984_06785	COG4608	Belongs to the ABC transporter superfamily
NR984_06790	COG0456	acetyltransferase
NR984_06795	COG1393	Belongs to the ArsC family
NR984_06800	COG0861	Integral membrane protein TerC family
NR984_06810	COG4862	establishment of competence for transformation
NR984_06830	COG4565	transcriptional regulatory protein
NR984_06835	COG3290	protein histidine kinase activity
NR984_06840	COG3290	protein histidine kinase activity
NR984_06845	COG4469	Competence protein
NR984_06850	COG1164	Oligoendopeptidase f
NR984_06860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NR984_06865	COG2346	COG2346, Truncated hemoglobins
NR984_06870	COG0741	lytic transglycosylase activity
NR984_06875	COG4116	CYTH
NR984_06885	COG2357	RelA SpoT domain protein
NR984_06890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NR984_06895	COG0564	pseudouridine synthase activity
NR984_06900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NR984_06905	COG0569	domain protein
NR984_06905	COG0475	glutathione-regulated potassium exporter activity
NR984_06910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NR984_06915	COG0352	thiamine-phosphate diphosphorylase activity
NR984_06925	COG2104	thiamine diphosphate biosynthetic process
NR984_06930	COG2022	thiamine diphosphate biosynthetic process
NR984_06935	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NR984_06940	COG0351	phosphomethylpyrimidine kinase
NR984_06945	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NR984_07005	COG0210	DNA helicase
NR984_07015	COG0586	Pfam SNARE associated Golgi protein
NR984_07020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NR984_07025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NR984_07030	COG2246	polysaccharide biosynthetic process
NR984_07035	COG2153	protein acetylation
NR984_07040	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NR984_07045	COG2382	esterase
NR984_07060	COG0626	cystathionine gamma-synthase activity
NR984_07065	COG0626	cystathionine gamma-synthase activity
NR984_07070	COG5505	Protein of unknown function (DUF819)
NR984_07085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NR984_07090	COG3507	Belongs to the glycosyl hydrolase 43 family
NR984_07110	COG0110	maltose O-acetyltransferase activity
NR984_07120	COG0583	DNA-binding transcription factor activity
NR984_07125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NR984_07130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NR984_07135	COG0583	DNA-binding transcription factor activity
NR984_07140	COG0697	spore germination
NR984_07145	COG0346	lactoylglutathione lyase activity
NR984_07155	COG1388	LysM domain
NR984_07155	COG3584	3D domain protein
NR984_07160	COG2814	Major facilitator Superfamily
NR984_07165	COG1309	transcriptional regulator
NR984_07185	COG5444	nuclease activity
NR984_07190	COG4195	phage-related replication protein
NR984_07195	COG2856	Zn peptidase
NR984_07200	COG1396	sequence-specific DNA binding
NR984_07215	COG1522	sequence-specific DNA binding
NR984_07220	COG1484	DNA-dependent DNA replication
NR984_07240	COG1595	DNA-templated transcription, initiation
NR984_07245	COG3728	DNA packaging
NR984_07245	COG5484	DNA packaging
NR984_07250	COG1783	phage Terminase large subunit
NR984_07255	COG5518	Phage portal protein
NR984_07260	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NR984_07265	COG4653	Phage capsid family
NR984_07315	COG3953	SLT domain
NR984_07315	COG5412	phage tail tape measure protein
NR984_07320	COG1652	LysM domain
NR984_07325	COG4193	domain, Protein
NR984_07335	COG3628	GPW Gp25 family protein
NR984_07340	COG3299	homolog of phage Mu protein gp47
NR984_07345	COG3778	Protein conserved in bacteria
NR984_07380	COG1802	Transcriptional regulator
NR984_07385	COG1063	alcohol dehydrogenase
NR984_07390	COG1312	Catalyzes the dehydration of D-mannonate
NR984_07395	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_07400	COG1063	alcohol dehydrogenase
NR984_07405	COG2271	Major facilitator Superfamily
NR984_07425	COG0306	phosphate transporter
NR984_07430	COG1392	Phosphate transport regulator
NR984_07435	COG0405	Gamma-glutamyltransferase
NR984_07440	COG5578	integral membrane protein
NR984_07445	COG2972	Histidine kinase
NR984_07450	COG4753	response regulator
NR984_07450	COG2207	Transcriptional regulator
NR984_07455	COG1653	transport
NR984_07460	COG1175	transmembrane transport
NR984_07465	COG0395	ABC-type sugar transport system, permease component
NR984_07470	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NR984_07475	COG2207	Transcriptional regulator
NR984_07480	COG2755	lipolytic protein G-D-S-L family
NR984_07490	COG5578	integral membrane protein
NR984_07495	COG3401	FG-GAP repeat protein
NR984_07510	COG2755	lipolytic protein G-D-S-L family
NR984_07515	COG3401	FG-GAP repeat protein
NR984_07520	COG0667	Aldo Keto reductase
NR984_07525	COG2755	lipolytic protein G-D-S-L family
NR984_07530	COG1874	Beta-galactosidase
NR984_07540	COG1653	transport
NR984_07545	COG4209	transmembrane transport
NR984_07550	COG0395	ABC-type sugar transport system, permease component
NR984_07555	COG0531	amino acid
NR984_07560	COG0346	lactoylglutathione lyase activity
NR984_07570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NR984_07575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NR984_07580	COG2362	D-Aminopeptidase
NR984_07585	COG0601	transmembrane transport
NR984_07590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NR984_07595	COG0444	Belongs to the ABC transporter superfamily
NR984_07600	COG4166	transmembrane transport
NR984_07605	COG1619	proteins homologs of microcin C7 resistance protein MccF
NR984_07610	COG4948	Mandelate Racemase Muconate Lactonizing
NR984_07615	COG0791	NLP P60 protein
NR984_07620	COG4608	Belongs to the ABC transporter superfamily
NR984_07625	COG1834	amidinotransferase
NR984_07630	COG1607	acyl-coa hydrolase
NR984_07635	COG2323	membrane
NR984_07640	COG3866	Pectate lyase
NR984_07660	COG2318	DinB family
NR984_07665	COG2076	Multidrug Resistance protein
NR984_07670	COG2076	Multidrug Resistance protein
NR984_07675	COG0788	formyltetrahydrofolate deformylase activity
NR984_07680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NR984_07685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NR984_07690	COG1764	response to oxidative stress
NR984_07695	COG1846	Transcriptional regulator
NR984_07700	COG1764	response to oxidative stress
NR984_07710	COG0590	tRNA wobble adenosine to inosine editing
NR984_07715	COG0406	alpha-ribazole phosphatase activity
NR984_07730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NR984_07735	COG1404	Belongs to the peptidase S8 family
NR984_07745	COG2239	Acts as a magnesium transporter
NR984_07755	COG0789	Transcriptional regulator
NR984_07770	COG1846	Transcriptional regulator
NR984_07775	COG1793	dna ligase
NR984_07775	COG3285	dna ligase
NR984_07780	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NR984_07785	COG3300	MHYT domain
NR984_07785	COG5001	Diguanylate cyclase
NR984_07790	COG0586	Pfam SNARE associated Golgi protein
NR984_07800	COG1191	sigma factor activity
NR984_07820	COG0501	Belongs to the peptidase M48B family
NR984_07825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NR984_07830	COG0768	penicillin binding
NR984_07845	COG3594	Acyltransferase
NR984_07850	COG5002	protein histidine kinase activity
NR984_07855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NR984_07865	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NR984_07870	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NR984_07875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NR984_07880	COG0436	Aminotransferase
NR984_07885	COG1850	ribulose-bisphosphate carboxylase activity
NR984_07895	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NR984_07895	COG0235	Class ii aldolase
NR984_07900	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NR984_07905	COG0346	lactoylglutathione lyase activity
NR984_07910	COG3339	Conserved Protein
NR984_07920	COG3852	Histidine kinase
NR984_07925	COG1846	Transcriptional regulator
NR984_07930	COG1360	Flagellar Motor Protein
NR984_07935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NR984_07940	COG0542	response to heat
NR984_07945	COG3949	Membrane
NR984_07950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NR984_07955	COG0720	synthase
NR984_07960	COG0602	queuosine metabolic process
NR984_07965	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NR984_07980	COG3739	integral membrane protein
NR984_07985	COG3655	Transcriptional regulator
NR984_08020	COG4873	Protein conserved in bacteria
NR984_08030	COG3773	Cell wall hydrolase
NR984_08035	COG2244	polysaccharide biosynthetic process
NR984_08040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_08045	COG2217	Heavy metal translocating P-type atpase
NR984_08050	COG0006	proline dipeptidase activity
NR984_08065	COG1609	Transcriptional regulator
NR984_08070	COG3711	transcriptional antiterminator
NR984_08075	COG1263	PTS System
NR984_08075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_08075	COG2190	(PTS) system
NR984_08080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_08085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NR984_08095	COG1533	DNA photolyase activity
NR984_08100	COG0456	acetyltransferase
NR984_08105	COG0840	transmembrane signaling receptor activity
NR984_08110	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_08115	COG2084	Dehydrogenase
NR984_08120	COG2340	Cysteine-rich secretory protein family
NR984_08125	COG0768	penicillin binding
NR984_08130	COG4191	Histidine kinase
NR984_08135	COG0436	Aminotransferase
NR984_08145	COG1714	RDD family
NR984_08155	COG0784	Response regulator, receiver
NR984_08155	COG0835	chemotaxis
NR984_08165	COG2814	Major facilitator Superfamily
NR984_08170	COG1376	ErfK ybiS ycfS ynhG family protein
NR984_08175	COG1408	metallophosphoesterase
NR984_08180	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_08185	COG2200	EAL domain
NR984_08195	COG4703	Protein of unknown function (DUF1797)
NR984_08205	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
NR984_08215	COG0517	IMP dehydrogenase activity
NR984_08220	COG0583	DNA-binding transcription factor activity
NR984_08225	COG0716	FMN binding
NR984_08235	COG0716	FMN binding
NR984_08240	COG2171	N-acyltransferase activity
NR984_08245	COG1473	amidohydrolase
NR984_08255	COG0450	alkyl hydroperoxide reductase
NR984_08260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_08275	COG0746	molybdenum cofactor guanylyltransferase activity
NR984_08280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NR984_08285	COG0303	'Molybdopterin
NR984_08290	COG1763	Mo-molybdopterin cofactor biosynthetic process
NR984_08295	COG0314	molybdopterin synthase activity
NR984_08300	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NR984_08310	COG1132	(ABC) transporter
NR984_08315	COG1132	(ABC) transporter
NR984_08325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NR984_08330	COG1136	(ABC) transporter
NR984_08335	COG0577	efflux transmembrane transporter activity
NR984_08340	COG1349	DNA-binding transcription factor activity
NR984_08345	COG1105	Belongs to the carbohydrate kinase PfkB family
NR984_08350	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NR984_08350	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NR984_08350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_08370	COG0488	(ABC) transporter
NR984_08380	COG2309	aminopeptidase activity
NR984_08390	COG1077	Cell shape determining protein MreB Mrl
NR984_08395	COG2002	toxin-antitoxin pair type II binding
NR984_08400	COG3852	Histidine kinase
NR984_08405	COG0569	domain protein
NR984_08410	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NR984_08415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NR984_08420	COG5503	Protein of unknown function (DUF1447)
NR984_08425	COG0561	phosphatase activity
NR984_08430	COG0242	peptide deformylase activity
NR984_08440	COG0497	DNA recombination
NR984_08445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NR984_08450	COG0022	dehydrogenase e1 component
NR984_08455	COG0508	dehydrogenase complex catalyzes the overall conversion of
NR984_08460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NR984_08465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_08475	COG1982	Orn Lys Arg decarboxylase major
NR984_08480	COG4476	Belongs to the UPF0223 family
NR984_08485	COG4493	Belongs to the UPF0637 family
NR984_08495	COG0483	inositol monophosphate 1-phosphatase activity
NR984_08515	COG1595	DNA-templated transcription, initiation
NR984_08530	COG1217	gtp-binding protein TYPA
NR984_08540	COG1846	Transcriptional regulator
NR984_08545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NR984_08550	COG4896	Protein conserved in bacteria
NR984_08560	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NR984_08565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NR984_08570	COG2066	Belongs to the glutaminase family
NR984_08575	COG4838	Belongs to the UPF0358 family
NR984_08580	COG0772	Belongs to the SEDS family
NR984_08585	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NR984_08590	COG1612	heme a metabolic process
NR984_08595	COG0109	protoheme IX farnesyltransferase activity
NR984_08600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NR984_08600	COG2010	Cytochrome c
NR984_08605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NR984_08610	COG1845	cytochrome c oxidase, subunit III
NR984_08615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NR984_08620	COG3336	cytochrome c oxidase
NR984_08630	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
NR984_08635	COG2340	Cysteine-rich secretory protein family
NR984_08650	COG3679	Belongs to the UPF0342 family
NR984_08655	COG4471	UPF0298 protein
NR984_08665	COG0742	ribosomal rna small subunit methyltransferase
NR984_08670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NR984_08675	COG3314	Sporulation integral membrane protein YlbJ
NR984_08680	COG3480	Lon protease (S16) C-terminal proteolytic domain
NR984_08685	COG1323	Belongs to the UPF0348 family
NR984_08690	COG1399	metal-binding, possibly nucleic acid-binding protein
NR984_08695	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NR984_08705	COG0454	-acetyltransferase
NR984_08710	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NR984_08715	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NR984_08720	COG2001	Belongs to the MraZ family
NR984_08725	COG0275	rRNA processing
NR984_08730	COG4839	cell division protein FtsL
NR984_08735	COG0768	penicillin binding
NR984_08740	COG0768	penicillin binding
NR984_08745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NR984_08750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NR984_08755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NR984_08760	COG0772	Belongs to the SEDS family
NR984_08765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NR984_08770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NR984_08775	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NR984_08780	COG3879	Bacterial protein of unknown function (DUF881)
NR984_08785	COG3879	Bacterial protein of unknown function (DUF881)
NR984_08790	COG3856	small basic protein
NR984_08795	COG0849	cell division
NR984_08800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NR984_08810	COG4412	M6 family metalloprotease domain protein
NR984_08810	COG1404	Belongs to the peptidase S8 family
NR984_08820	COG1191	sigma factor activity
NR984_08825	COG1191	sigma factor activity
NR984_08830	COG1119	ATPase activity
NR984_08835	COG0500	methyltransferase
NR984_08840	COG1873	PFAM PRC-barrel domain
NR984_08845	COG1496	oxidoreductase activity
NR984_08850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NR984_08855	COG1799	cell septum assembly
NR984_08860	COG0762	integral membrane protein
NR984_08865	COG2302	S4 RNA-binding domain
NR984_08870	COG3599	regulation of cell shape
NR984_08875	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NR984_08880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NR984_08885	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NR984_08890	COG0564	pseudouridine synthase activity
NR984_08895	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NR984_08900	COG2233	PERMEase
NR984_08905	COG0540	Belongs to the ATCase OTCase family
NR984_08910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NR984_08915	COG0505	Belongs to the CarA family
NR984_08920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NR984_08925	COG0543	2 iron, 2 sulfur cluster binding
NR984_08930	COG0167	dihydroorotate dehydrogenase activity
NR984_08935	COG0284	orotidine-5'-phosphate decarboxylase activity
NR984_08940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NR984_08950	COG0175	sulfate reduction
NR984_08955	COG0306	phosphate transporter
NR984_08960	COG2046	Belongs to the sulfate adenylyltransferase family
NR984_08965	COG0529	Catalyzes the synthesis of activated sulfate
NR984_08970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NR984_08975	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
NR984_08980	COG1648	precorrin-2 dehydrogenase activity
NR984_08990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NR984_08995	COG1561	YicC-like family, N-terminal region
NR984_09000	COG2052	Domain of unknown function (DUF370)
NR984_09005	COG0194	GDP metabolic process
NR984_09010	COG1758	RNA polymerase activity
NR984_09015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NR984_09020	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NR984_09025	COG0242	peptide deformylase activity
NR984_09030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NR984_09035	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NR984_09035	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NR984_09040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NR984_09045	COG0631	protein serine/threonine phosphatase activity
NR984_09050	COG2815	serine threonine protein kinase
NR984_09050	COG0515	serine threonine protein kinase
NR984_09055	COG1162	GTPase activity
NR984_09060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NR984_09065	COG1564	THIamine pyrophosphokinase
NR984_09075	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NR984_09080	COG1302	Protein conserved in bacteria
NR984_09085	COG1461	Dihydroxyacetone kinase
NR984_09090	COG1760	l-serine dehydratase
NR984_09095	COG1760	l-serine dehydratase
NR984_09100	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NR984_09105	COG1349	DNA-binding transcription factor activity
NR984_09110	COG0416	fatty acid biosynthetic process
NR984_09115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NR984_09120	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_09125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NR984_09130	COG0571	ribonuclease III activity
NR984_09135	COG1196	nuclear chromosome segregation
NR984_09140	COG0552	protein localization to endoplasmic reticulum
NR984_09145	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NR984_09150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NR984_09155	COG0228	four-way junction DNA binding
NR984_09160	COG1837	Belongs to the UPF0109 family
NR984_09170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NR984_09175	COG0336	Belongs to the RNA methyltransferase TrmD family
NR984_09180	COG0335	large ribosomal subunit rRNA binding
NR984_09185	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NR984_09190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NR984_09200	COG2257	FlhB HrpN YscU SpaS Family
NR984_09205	COG0045	succinate-CoA ligase (ADP-forming) activity
NR984_09210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NR984_09215	COG0758	DNA mediated transformation
NR984_09220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NR984_09225	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NR984_09230	COG4974	Belongs to the 'phage' integrase family
NR984_09235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NR984_09240	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NR984_09245	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NR984_09250	COG1815	bacterial-type flagellum-dependent cell motility
NR984_09255	COG1558	bacterial-type flagellum-dependent cell motility
NR984_09260	COG1677	Flagellar hook-basal body complex protein FliE
NR984_09265	COG1766	The M ring may be actively involved in energy transduction
NR984_09270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NR984_09275	COG1317	bacterial-type flagellum organization
NR984_09280	COG1157	protein secretion by the type III secretion system
NR984_09285	COG2882	bacterial-type flagellum organization
NR984_09295	COG3144	bacterial-type flagellum assembly
NR984_09300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NR984_09305	COG4786	Flagellar basal body rod
NR984_09310	COG1582	Flagellar protein (FlbD)
NR984_09315	COG1580	Controls the rotational direction of flagella during chemotaxis
NR984_09320	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NR984_09325	COG1776	CheC inhibitor of MCP methylation
NR984_09325	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NR984_09330	COG2201	protein-glutamate methylesterase activity
NR984_09335	COG3190	flagellar
NR984_09340	COG1338	Plays a role in the flagellum-specific transport system
NR984_09345	COG1987	bacterial-type flagellum assembly
NR984_09350	COG1684	flagellar biosynthetic protein fliR
NR984_09355	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NR984_09360	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NR984_09365	COG1419	protein localization to endoplasmic reticulum
NR984_09370	COG0455	bacterial-type flagellum organization
NR984_09375	COG2201	protein-glutamate methylesterase activity
NR984_09380	COG0643	Histidine kinase
NR984_09380	COG2198	Histidine kinase
NR984_09385	COG0835	chemotaxis
NR984_09390	COG1776	CheC inhibitor of MCP methylation
NR984_09395	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NR984_09410	COG0052	Belongs to the universal ribosomal protein uS2 family
NR984_09415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NR984_09420	COG0528	UMP kinase activity
NR984_09425	COG0233	cytoplasmic translational termination
NR984_09430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NR984_09435	COG4589	Belongs to the CDS family
NR984_09440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NR984_09445	COG0750	zinc metalloprotease
NR984_09450	COG0442	prolyl-tRNA aminoacylation
NR984_09455	COG2176	DNA-directed DNA polymerase activity
NR984_09480	COG0779	Required for maturation of 30S ribosomal subunits
NR984_09485	COG0195	Participates in both transcription termination and antitermination
NR984_09490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NR984_09495	COG1358	cellular component organization or biogenesis
NR984_09500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NR984_09505	COG1550	Protein conserved in bacteria
NR984_09510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NR984_09515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NR984_09520	COG0196	riboflavin kinase activity
NR984_09525	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NR984_09530	COG1185	polyribonucleotide nucleotidyltransferase activity
NR984_09535	COG0726	polysaccharide deacetylase
NR984_09540	COG0612	Peptidase, M16
NR984_09545	COG1873	PFAM PRC-barrel domain
NR984_09550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NR984_09555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NR984_09560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NR984_09565	COG0527	aspartate kinase activity
NR984_09575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NR984_09580	COG0740	serine-type endopeptidase activity
NR984_09590	COG1674	ftsk spoiiie
NR984_09590	COG4980	gas vesicle protein
NR984_09595	COG2188	Transcriptional regulator
NR984_09600	COG2814	Major facilitator Superfamily
NR984_09605	COG0612	Peptidase, M16
NR984_09610	COG0612	Peptidase, M16
NR984_09615	COG0300	oxidoreductase activity
NR984_09630	COG1426	Protein conserved in bacteria
NR984_09635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NR984_09640	COG1546	Belongs to the CinA family
NR984_09640	COG1058	Belongs to the CinA family
NR984_09650	COG1418	mRNA catabolic process
NR984_09655	COG1692	metallophosphoesterase
NR984_09660	COG2359	stage V sporulation protein S
NR984_09670	COG1063	alcohol dehydrogenase
NR984_09675	COG0156	8-amino-7-oxononanoate synthase activity
NR984_09680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NR984_09685	COG4550	Control of competence regulator ComK, YlbF/YmcA
NR984_09695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NR984_09700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NR984_09705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NR984_09710	COG5444	nuclease activity
NR984_09725	COG0523	cobalamin synthesis protein
NR984_09735	COG1247	-acetyltransferase
NR984_09755	COG3619	membrane
NR984_09760	COG3263	regulation of cellular component size
NR984_09765	COG2814	Major facilitator Superfamily
NR984_09770	COG2814	Major facilitator Superfamily
NR984_09780	COG0393	Putative heavy-metal-binding
NR984_09785	COG0398	Pfam SNARE associated Golgi protein
NR984_09790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NR984_09795	COG1819	glycosyl
NR984_09800	COG0531	amino acid
NR984_09805	COG5577	PFAM Coat F domain
NR984_09815	COG1388	LysM domain
NR984_09815	COG3858	chitin binding
NR984_09820	COG1309	transcriptional regulator
NR984_09825	COG3631	Ketosteroid isomerase-related protein
NR984_09830	COG0702	epimerase
NR984_09840	COG1764	response to oxidative stress
NR984_09845	COG2076	Multidrug Resistance protein
NR984_09865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NR984_09870	COG1923	regulation of RNA biosynthetic process
NR984_09880	COG1780	Probably involved in ribonucleotide reductase function
NR984_09885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NR984_09890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NR984_09895	COG4112	unkown
NR984_09910	COG0735	belongs to the Fur family
NR984_09915	COG1802	Transcriptional regulator
NR984_09920	COG0697	spore germination
NR984_09955	COG1309	transcriptional regulator
NR984_10000	COG0464	growth
NR984_10005	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NR984_10010	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NR984_10015	COG0789	Transcriptional regulator
NR984_10020	COG0174	glutamine synthetase
NR984_10055	COG1073	alpha beta
NR984_10100	COG1309	transcriptional regulator
NR984_10105	COG2076	Multidrug Resistance protein
NR984_10110	COG2076	Multidrug Resistance protein
NR984_10140	COG3546	catalase activity
NR984_10165	COG1846	Transcriptional regulator
NR984_10170	COG0778	Nitroreductase
NR984_10175	COG0346	lactoylglutathione lyase activity
NR984_10180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NR984_10185	COG0655	NAD(P)H dehydrogenase (quinone) activity
NR984_10210	COG3209	COG3209 Rhs family protein
NR984_10215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NR984_10220	COG1388	LysM domain
NR984_10225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NR984_10230	COG4224	UPF0291 protein
NR984_10235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NR984_10245	COG3763	UPF0154 protein
NR984_10255	COG0785	Cytochrome C biogenesis protein
NR984_10260	COG2201	protein-glutamate methylesterase activity
NR984_10265	COG4846	Membrane protein involved in cytochrome C biogenesis
NR984_10275	COG0071	Belongs to the small heat shock protein (HSP20) family
NR984_10290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NR984_10295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_10315	COG0824	Thioesterase
NR984_10340	COG4841	protein insertion into membrane
NR984_10345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NR984_10350	COG1832	CoA-binding protein
NR984_10355	COG0187	DNA topoisomerase II activity
NR984_10360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NR984_10365	COG1609	Transcriptional regulator
NR984_10380	COG2160	L-arabinose isomerase activity
NR984_10405	COG1115	amino acid carrier protein
NR984_10415	COG2181	nitrate reductase activity
NR984_10420	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
NR984_10425	COG1140	nitrate reductase beta subunit
NR984_10430	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NR984_10445	COG0535	radical SAM domain protein
NR984_10450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NR984_10460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NR984_10465	COG2223	nitrite transmembrane transporter activity
NR984_10485	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NR984_10495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NR984_10505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NR984_10515	COG0492	ferredoxin-NADP+ reductase activity
NR984_10530	COG3420	alginic acid biosynthetic process
NR984_10535	COG1114	Component of the transport system for branched-chain amino acids
NR984_10540	COG1064	alcohol dehydrogenase
NR984_10545	COG0789	Transcriptional regulator
NR984_10570	COG1024	Enoyl-CoA hydratase
NR984_10575	COG1012	belongs to the aldehyde dehydrogenase family
NR984_10580	COG2084	Dehydrogenase
NR984_10585	COG1960	acyl-CoA dehydrogenase activity
NR984_10590	COG1482	cell wall glycoprotein biosynthetic process
NR984_10595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NR984_10595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_10595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NR984_10615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_10615	COG3711	transcriptional antiterminator
NR984_10630	COG1725	Transcriptional regulator
NR984_10635	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_10640	COG1312	Catalyzes the dehydration of D-mannonate
NR984_10655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NR984_10665	COG1609	Transcriptional regulator
NR984_10670	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NR984_10675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NR984_10680	COG0640	Transcriptional regulator
NR984_10685	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
NR984_10705	COG2404	hydrolase activity, acting on ester bonds
NR984_10710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NR984_10720	COG2027	D-alanyl-D-alanine carboxypeptidase
NR984_10725	COG1252	NADH dehydrogenase
NR984_10735	COG0166	Belongs to the GPI family
NR984_10745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NR984_10750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NR984_10755	COG1024	Enoyl-CoA hydratase
NR984_10760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NR984_10765	COG0511	ligase activity, forming carbon-carbon bonds
NR984_10770	COG0439	Biotin carboxylase
NR984_10775	COG0318	PFAM AMP-dependent synthetase and ligase
NR984_10780	COG1960	acyl-CoA dehydrogenase activity
NR984_10785	COG2249	NAD(P)H dehydrogenase (quinone) activity
NR984_10790	COG1733	regulation of RNA biosynthetic process
NR984_10795	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NR984_10800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NR984_10810	COG2323	membrane
NR984_10820	COG0306	phosphate transporter
NR984_10825	COG0175	sulfate reduction
NR984_10830	COG1809	phosphosulfolactate synthase activity
NR984_10835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NR984_10840	COG4948	Mandelate Racemase Muconate Lactonizing
NR984_10845	COG2814	Major facilitator Superfamily
NR984_10850	COG0463	Glycosyl transferase, family 2
NR984_10860	COG0493	'glutamate synthase
NR984_10865	COG0067	glutamate synthase
NR984_10865	COG0069	glutamate synthase activity
NR984_10865	COG0070	glutamate synthase
NR984_10870	COG0583	DNA-binding transcription factor activity
NR984_10890	COG1846	Transcriptional regulator
NR984_10900	COG1132	(ABC) transporter
NR984_10910	COG0300	oxidoreductase activity
NR984_10915	COG0574	Belongs to the PEP-utilizing enzyme family
NR984_10915	COG3848	Pyruvate phosphate dikinase
NR984_10925	COG0477	Major facilitator Superfamily
NR984_10930	COG0243	molybdopterin cofactor binding
NR984_10935	COG1846	Transcriptional regulator
NR984_10945	COG0531	amino acid
NR984_10955	COG0531	amino acid
NR984_10960	COG0531	amino acid
NR984_10965	COG0697	spore germination
NR984_10975	COG0488	(ABC) transporter
NR984_10980	COG0840	transmembrane signaling receptor activity
NR984_10985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NR984_10990	COG1404	Belongs to the peptidase S8 family
NR984_11000	COG1309	transcriptional regulator
NR984_11005	COG1846	Transcriptional regulator
NR984_11035	COG1309	transcriptional regulator
NR984_11040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NR984_11045	COG3708	Transcriptional regulator
NR984_11055	COG2378	regulation of single-species biofilm formation
NR984_11065	COG0640	Transcriptional regulator
NR984_11070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NR984_11080	COG0531	amino acid
NR984_11085	COG0741	lytic transglycosylase activity
NR984_11090	COG1086	Polysaccharide biosynthesis protein
NR984_11110	COG2322	membrane
NR984_11125	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NR984_11130	COG3584	3D domain protein
NR984_11130	COG1388	LysM domain
NR984_11135	COG0514	ATP-dependent DNA helicase (RecQ)
NR984_11160	COG2315	Protein conserved in bacteria
NR984_11175	COG2427	Protein of unknown function (DUF1641)
NR984_11180	COG3383	formate dehydrogenase (NAD+) activity
NR984_11205	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
NR984_11265	COG2267	carboxylic ester hydrolase activity
NR984_11280	COG1280	lysine exporter protein (LysE YggA)
NR984_11285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NR984_11295	COG0574	Belongs to the PEP-utilizing enzyme family
NR984_11295	COG3848	Pyruvate phosphate dikinase
NR984_11300	COG1309	transcriptional regulator
NR984_11315	COG2318	DinB family
NR984_11320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NR984_11325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NR984_11340	COG1012	belongs to the aldehyde dehydrogenase family
NR984_11345	COG2814	Major facilitator Superfamily
NR984_11360	COG1657	PFAM Prenyltransferase squalene oxidase
NR984_11365	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NR984_11375	COG0733	neurotransmitter:sodium symporter activity
NR984_11380	COG0385	Bile acid
NR984_11385	COG0508	dehydrogenase complex catalyzes the overall conversion of
NR984_11390	COG0567	Dehydrogenase, E1 component
NR984_11395	COG4548	von Willebrand factor, type A
NR984_11400	COG0714	Associated with various cellular activities
NR984_11405	COG2032	superoxide dismutase activity
NR984_11410	COG0791	NLP P60 protein
NR984_11410	COG1388	LysM domain
NR984_11415	COG0534	Mate efflux family protein
NR984_11420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NR984_11425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NR984_11435	COG2962	Rard protein
NR984_11445	COG4305	rare lipoprotein A
NR984_11455	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_11460	COG1733	regulation of RNA biosynthetic process
NR984_11465	COG0778	Nitroreductase
NR984_11470	COG0400	carboxylic ester hydrolase activity
NR984_11480	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NR984_11485	COG0793	Belongs to the peptidase S41A family
NR984_11485	COG3409	Peptidoglycan-binding domain 1 protein
NR984_11490	COG2226	methyltransferase
NR984_11500	COG1876	peptidase activity
NR984_11505	COG0813	purine-nucleoside phosphorylase activity
NR984_11510	COG0701	Predicted permease
NR984_11530	COG0671	phosphoesterase, PA-phosphatase related
NR984_11550	COG4479	Belongs to the UPF0346 family
NR984_11560	COG1509	lysine 2,3-aminomutase activity
NR984_11565	COG0456	acetyltransferase
NR984_11570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NR984_11575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NR984_11580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NR984_11585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NR984_11600	COG0456	acetyltransferase
NR984_11605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NR984_11610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NR984_11615	COG1846	Transcriptional regulator
NR984_11625	COG3706	GGDEF domain
NR984_11630	COG0534	Mate efflux family protein
NR984_11645	COG4698	Protein conserved in bacteria
NR984_11650	COG2755	lipolytic protein G-D-S-L family
NR984_11655	COG1999	signal sequence binding
NR984_11670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NR984_11675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NR984_11680	COG1272	protein, Hemolysin III
NR984_11685	COG0204	Acyl-transferase
NR984_11690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NR984_11695	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NR984_11705	COG2136	Putative SAM-dependent methyltransferase
NR984_11705	COG2521	methyltransferase
NR984_11715	COG0129	dihydroxy-acid dehydratase activity
NR984_11720	COG1413	lyase activity
NR984_11725	COG1418	mRNA catabolic process
NR984_11730	COG0386	Belongs to the glutathione peroxidase family
NR984_11735	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NR984_11740	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NR984_11745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NR984_11755	COG1278	Cold shock
NR984_11775	COG0328	RNA-DNA hybrid ribonuclease activity
NR984_11780	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NR984_11785	COG0328	RNA-DNA hybrid ribonuclease activity
NR984_11795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NR984_11810	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NR984_11820	COG1755	Isoprenylcysteine carboxyl methyltransferase
NR984_11825	COG3424	synthase
NR984_11830	COG0456	acetyltransferase
NR984_11835	COG2233	PERMEase
NR984_11840	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NR984_11845	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NR984_11850	COG1199	ATP-dependent helicase activity
NR984_11865	COG0116	Belongs to the methyltransferase superfamily
NR984_11875	COG3599	regulation of cell shape
NR984_11880	COG4474	Belongs to the UPF0398 family
NR984_11890	COG3359	exonuclease
NR984_11895	COG1205	dead DEAH box helicase
NR984_11895	COG1111	helicase
NR984_11900	COG2190	(PTS) system
NR984_11905	COG0071	Belongs to the small heat shock protein (HSP20) family
NR984_11940	COG3331	DNA recombination
NR984_11945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NR984_11945	COG4499	WXG100 protein secretion system (Wss), protein YukC
NR984_11955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NR984_11960	COG3935	DnaD domain protein
NR984_11965	COG0017	Asparaginyl-tRNA synthetase
NR984_11970	COG0436	Aminotransferase
NR984_11975	COG5353	protein conserved in bacteria
NR984_11985	COG1199	ATP-dependent helicase activity
NR984_11985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NR984_11990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NR984_11995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NR984_12000	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NR984_12010	COG0617	tRNA 3'-terminal CCA addition
NR984_12015	COG0438	transferase activity, transferring glycosyl groups
NR984_12020	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
NR984_12025	COG1803	Methylglyoxal synthase
NR984_12030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NR984_12035	COG1694	Mazg nucleotide pyrophosphohydrolase
NR984_12040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NR984_12050	COG4347	Protein of unknown function (DUF1405)
NR984_12060	COG2010	Cytochrome c
NR984_12060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NR984_12065	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NR984_12070	COG0723	plastoquinol--plastocyanin reductase activity
NR984_12080	COG5582	Belongs to the UPF0302 family
NR984_12085	COG0457	Tetratricopeptide repeat
NR984_12090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NR984_12100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NR984_12110	COG0133	tryptophan synthase activity
NR984_12115	COG0135	phosphoribosylanthranilate isomerase activity
NR984_12120	COG0134	indole-3-glycerol-phosphate synthase activity
NR984_12125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NR984_12130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NR984_12135	COG4401	Chorismate mutase type I
NR984_12140	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NR984_12145	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NR984_12150	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NR984_12155	COG0105	UTP biosynthetic process
NR984_12160	COG0142	geranyltranstransferase activity
NR984_12165	COG2226	methyltransferase
NR984_12170	COG0142	geranyltranstransferase activity
NR984_12185	COG0776	regulation of translation
NR984_12190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NR984_12205	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NR984_12210	COG1160	GTP binding
NR984_12235	COG1304	FMN binding
NR984_12240	COG0539	negative regulation of cytoplasmic translation
NR984_12245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NR984_12255	COG2959	enzyme of heme biosynthesis
NR984_12260	COG3409	Peptidoglycan-binding domain 1 protein
NR984_12260	COG3773	Cell wall hydrolase
NR984_12265	COG2339	peptidase activity
NR984_12275	COG0492	ferredoxin-NADP+ reductase activity
NR984_12280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NR984_12285	COG4862	establishment of competence for transformation
NR984_12290	COG1408	metallophosphoesterase
NR984_12300	COG1388	LysM domain
NR984_12305	COG1266	CAAX protease self-immunity
NR984_12310	COG0514	ATP-dependent DNA helicase (RecQ)
NR984_12315	COG4955	Helix-turn-helix domain
NR984_12320	COG1141	Ferredoxin
NR984_12325	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NR984_12330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NR984_12335	COG0739	heme binding
NR984_12345	COG1595	DNA-templated transcription, initiation
NR984_12350	COG1316	TRANSCRIPTIONal
NR984_12370	COG5002	protein histidine kinase activity
NR984_12375	COG0745	RESPONSE REGULATOR receiver
NR984_12380	COG5002	protein histidine kinase activity
NR984_12385	COG0745	RESPONSE REGULATOR receiver
NR984_12390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NR984_12395	COG1333	cytochrome c biogenesis protein
NR984_12400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_12405	COG1187	pseudouridine synthase activity
NR984_12410	COG0700	Nucleoside recognition
NR984_12415	COG2715	membrane protein required for spore maturation
NR984_12420	COG1686	Belongs to the peptidase S11 family
NR984_12430	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NR984_12435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NR984_12445	COG1547	Domain of unknown function (DUF309)
NR984_12450	COG0456	acetyltransferase
NR984_12455	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NR984_12460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NR984_12460	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NR984_12465	COG0307	riboflavin synthase, alpha
NR984_12470	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NR984_12470	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NR984_12495	COG0457	Tetratricopeptide repeat
NR984_12500	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NR984_12505	COG4086	secreted protein
NR984_12510	COG4195	phage-related replication protein
NR984_12515	COG0019	diaminopimelate decarboxylase activity
NR984_12525	COG0697	spore germination
NR984_12540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NR984_12575	COG1686	Belongs to the peptidase S11 family
NR984_12580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NR984_12585	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NR984_12590	COG4974	Belongs to the 'phage' integrase family
NR984_12600	COG0735	belongs to the Fur family
NR984_12605	COG1300	Membrane
NR984_12610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NR984_12630	COG2153	protein acetylation
NR984_12635	COG1379	DNA repair
NR984_12640	COG0494	nUDIX hydrolase
NR984_12650	COG1309	transcriptional regulator
NR984_12660	COG0667	Aldo Keto reductase
NR984_12670	COG1073	alpha beta
NR984_12680	COG4918	Iron-sulphur cluster biosynthesis
NR984_12690	COG0456	acetyltransferase
NR984_12690	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NR984_12695	COG2329	Antibiotic biosynthesis monooxygenase
NR984_12700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NR984_12710	COG0747	negative chemotaxis
NR984_12715	COG0601	transmembrane transport
NR984_12720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NR984_12725	COG0444	Belongs to the ABC transporter superfamily
NR984_12730	COG0534	Mate efflux family protein
NR984_12745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NR984_12755	COG2211	Major facilitator Superfamily
NR984_12760	COG0346	lactoylglutathione lyase activity
NR984_12765	COG1072	(Pantothenic acid kinase))
NR984_12775	COG1131	(ABC) transporter
NR984_12800	COG4195	phage-related replication protein
NR984_12805	COG0300	oxidoreductase activity
NR984_12815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NR984_12820	COG4187	Peptidase family M20/M25/M40
NR984_12825	COG1902	pentaerythritol trinitrate reductase activity
NR984_12830	COG0596	Alpha beta hydrolase
NR984_12835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NR984_12840	COG1234	tRNA 3'-trailer cleavage
NR984_12845	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NR984_12860	COG2358	TRAP transporter, solute receptor (TAXI family
NR984_12865	COG2188	Transcriptional regulator
NR984_12870	COG2723	6-phospho-beta-galactosidase activity
NR984_12875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NR984_12880	COG1447	Phosphotransferase system cellobiose-specific component IIA
NR984_12885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NR984_12890	COG1785	Belongs to the alkaline phosphatase family
NR984_12895	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_12900	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NR984_12905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NR984_12915	COG0706	membrane insertase activity
NR984_12920	COG2195	Cleaves the N-terminal amino acid of tripeptides
NR984_12925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NR984_12935	COG4129	membrane
NR984_12940	COG1126	abc transporter atp-binding protein
NR984_12945	COG0765	amino acid transport
NR984_12950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NR984_12960	COG1597	lipid kinase activity
NR984_12965	COG0508	dehydrogenase complex catalyzes the overall conversion of
NR984_12970	COG0022	dehydrogenase e1 component
NR984_12975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NR984_12980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NR984_12985	COG3426	butyrate kinase activity
NR984_12995	COG0280	phosphate acetyltransferase
NR984_13000	COG3290	protein histidine kinase activity
NR984_13000	COG3829	transcription factor binding
NR984_13010	COG0584	glycerophosphoryl diester phosphodiesterase
NR984_13015	COG0860	N-Acetylmuramoyl-L-alanine amidase
NR984_13030	COG1045	serine acetyltransferase
NR984_13040	COG0745	RESPONSE REGULATOR receiver
NR984_13045	COG0750	zinc metalloprotease
NR984_13050	COG0497	DNA recombination
NR984_13055	COG1438	arginine binding
NR984_13060	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NR984_13065	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NR984_13070	COG0142	geranyltranstransferase activity
NR984_13075	COG1722	exodeoxyribonuclease VII activity
NR984_13080	COG1570	exodeoxyribonuclease VII activity
NR984_13085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NR984_13090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NR984_13095	COG1302	Protein conserved in bacteria
NR984_13100	COG0439	Biotin carboxylase
NR984_13105	COG0511	ligase activity, forming carbon-carbon bonds
NR984_13145	COG3854	ATPases associated with a variety of cellular activities
NR984_13155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NR984_13160	COG0006	proline dipeptidase activity
NR984_13165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NR984_13175	COG3872	metal-dependent enzyme
NR984_13185	COG1752	Esterase of the alpha-beta hydrolase superfamily
NR984_13190	COG1321	iron dependent repressor
NR984_13195	COG0095	Lipoate-protein ligase
NR984_13200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NR984_13205	COG2113	Glycine betaine
NR984_13210	COG4176	ABC-type proline glycine betaine transport system permease component
NR984_13215	COG4175	Glycine betaine
NR984_13215	COG0517	IMP dehydrogenase activity
NR984_13220	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NR984_13225	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NR984_13230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NR984_13235	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NR984_13260	COG0681	Belongs to the peptidase S26 family
NR984_13285	COG4940	Competence protein ComGF
NR984_13295	COG4970	Tfp pilus assembly protein FimT
NR984_13300	COG4537	Required for transformation and DNA binding
NR984_13305	COG1459	type II secretion system
NR984_13310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NR984_13315	COG1366	Belongs to the anti-sigma-factor antagonist family
NR984_13325	COG1393	Belongs to the ArsC family
NR984_13335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NR984_13345	COG0011	TIGRFAM Protein of
NR984_13355	COG2866	Carboxypeptidase
NR984_13360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_13370	COG1368	sulfuric ester hydrolase activity
NR984_13375	COG1940	carbohydrate kinase activity
NR984_13380	COG4483	Protein conserved in bacteria
NR984_13385	COG0697	spore germination
NR984_13390	COG0457	Tetratricopeptide repeat
NR984_13390	COG0705	Rhomboid family
NR984_13400	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NR984_13405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NR984_13410	COG0438	transferase activity, transferring glycosyl groups
NR984_13425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NR984_13430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NR984_13435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NR984_13440	COG0581	inorganic phosphate transmembrane transporter activity
NR984_13445	COG0573	inorganic phosphate transmembrane transporter activity
NR984_13450	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NR984_13455	COG0768	penicillin binding
NR984_13460	COG0477	Major facilitator Superfamily
NR984_13465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NR984_13470	COG2839	Protein conserved in bacteria
NR984_13475	COG5521	maltodextrose utilization protein MalA
NR984_13480	COG1388	LysM domain
NR984_13485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NR984_13490	COG4709	membrane
NR984_13495	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
NR984_13500	COG0735	belongs to the Fur family
NR984_13505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NR984_13510	COG1121	(ABC) transporter
NR984_13515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NR984_13525	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NR984_13530	COG0513	Belongs to the DEAD box helicase family
NR984_13540	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NR984_13545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NR984_13550	COG2384	SAM-dependent methyltransferase
NR984_13590	COG5444	nuclease activity
NR984_13605	COG2010	Cytochrome c
NR984_13610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NR984_13615	COG0358	DNA primase activity
NR984_13620	COG1671	Belongs to the UPF0178 family
NR984_13625	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NR984_13630	COG0517	IMP dehydrogenase activity
NR984_13635	COG0751	glycine-tRNA ligase activity
NR984_13640	COG0752	glycyl-tRNA synthetase alpha subunit
NR984_13645	COG1381	Involved in DNA repair and RecF pathway recombination
NR984_13655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NR984_13660	COG0295	cytidine deaminase activity
NR984_13665	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NR984_13670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NR984_13675	COG1480	7TM receptor with intracellular HD hydrolase
NR984_13680	COG1702	phosphate starvation-inducible protein PhoH
NR984_13685	COG0561	phosphatase activity
NR984_13700	COG4864	UPF0365 protein
NR984_13705	COG1030	water channel activity
NR984_13710	COG1610	YqeY-like protein
NR984_13715	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NR984_13720	COG1283	sodium-dependent phosphate transmembrane transporter activity
NR984_13725	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NR984_13730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NR984_13735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NR984_13740	COG2264	protein methyltransferase activity
NR984_13745	COG0484	heat shock protein binding
NR984_13750	COG0443	Heat shock 70 kDa protein
NR984_13755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NR984_13760	COG1420	regulation of RNA biosynthetic process
NR984_13765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NR984_13770	COG0481	GTPase activity
NR984_13780	COG0860	N-Acetylmuramoyl-L-alanine amidase
NR984_13785	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NR984_13790	COG0268	Binds directly to 16S ribosomal RNA
NR984_13795	COG1466	dna polymerase III delta subunit
NR984_13805	COG0658	competence protein
NR984_13805	COG2333	competence protein COMEC
NR984_13810	COG2131	deaminase
NR984_13815	COG1555	photosystem II stabilization
NR984_13815	COG1596	polysaccharide export
NR984_13820	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NR984_13825	COG2226	methyltransferase
NR984_13830	COG0799	negative regulation of ribosome biogenesis
NR984_13835	COG1713	HD superfamily hydrolase involved in NAD metabolism
NR984_13840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NR984_13845	COG1534	Rna-binding protein
NR984_13850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NR984_13855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NR984_13860	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NR984_13875	COG2755	lipolytic protein G-D-S-L family
NR984_13880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NR984_13885	COG5609	conserved protein (DUF2294)
NR984_13890	COG3383	formate dehydrogenase (NAD+) activity
NR984_13895	COG2427	Protein of unknown function (DUF1641)
NR984_13915	COG1247	-acetyltransferase
NR984_13925	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NR984_13930	COG3616	Alanine racemase, N-terminal domain
NR984_13935	COG0251	oxidation-reduction process
NR984_13945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NR984_13950	COG0251	oxidation-reduction process
NR984_13970	COG0789	Transcriptional regulator
NR984_13970	COG4978	Transcriptional regulator
NR984_13975	COG0425	Belongs to the sulfur carrier protein TusA family
NR984_13975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NR984_13985	COG2197	response regulator
NR984_13990	COG4585	Histidine kinase
NR984_13995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_14000	COG0730	response to heat
NR984_14005	COG0425	Belongs to the sulfur carrier protein TusA family
NR984_14010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NR984_14010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NR984_14015	COG0425	Belongs to the sulfur carrier protein TusA family
NR984_14015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NR984_14020	COG2210	Belongs to the sulfur carrier protein TusA family
NR984_14025	COG1937	Protein conserved in bacteria
NR984_14065	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NR984_14070	COG0113	porphobilinogen synthase activity
NR984_14075	COG0803	Belongs to the bacterial solute-binding protein 9 family
NR984_14080	COG1121	(ABC) transporter
NR984_14085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NR984_14095	COG1942	4-Oxalocrotonate Tautomerase
NR984_14105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NR984_14110	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NR984_14115	COG1733	regulation of RNA biosynthetic process
NR984_14120	COG3239	Fatty acid desaturase
NR984_14125	COG4585	Histidine kinase
NR984_14130	COG2197	response regulator
NR984_14135	COG0492	ferredoxin-NADP+ reductase activity
NR984_14140	COG0747	negative chemotaxis
NR984_14145	COG0601	transmembrane transport
NR984_14150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NR984_14155	COG0444	Belongs to the ABC transporter superfamily
NR984_14160	COG4608	Belongs to the ABC transporter superfamily
NR984_14180	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_14195	COG2124	cytochrome p450
NR984_14200	COG0730	response to heat
NR984_14210	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_14215	COG1621	beta-fructofuranosidase activity
NR984_14220	COG3716	PTS system mannose fructose sorbose family IID component
NR984_14225	COG3715	PTS system
NR984_14230	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_14235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_14240	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NR984_14240	COG3933	PFAM sigma-54 factor interaction domain-containing protein
NR984_14260	COG2169	Transcriptional regulator
NR984_14265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NR984_14270	COG0656	L-ascorbic acid biosynthetic process
NR984_14275	COG2814	Major facilitator Superfamily
NR984_14280	COG1733	regulation of RNA biosynthetic process
NR984_14285	COG3340	Belongs to the peptidase S51 family
NR984_14290	COG1587	Uroporphyrinogen-III synthase
NR984_14300	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_14305	COG0583	DNA-binding transcription factor activity
NR984_14310	COG2814	Major facilitator Superfamily
NR984_14320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NR984_14320	COG2124	cytochrome p450
NR984_14325	COG1309	transcriptional regulator
NR984_14330	COG1404	Belongs to the peptidase S8 family
NR984_14335	COG2226	methyltransferase
NR984_14360	COG0626	cystathionine gamma-synthase activity
NR984_14365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NR984_14370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NR984_14375	COG2226	methyltransferase
NR984_14390	COG0768	penicillin binding
NR984_14395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NR984_14400	COG0572	uridine kinase
NR984_14405	COG0826	peptidase U32
NR984_14410	COG0826	peptidase U32
NR984_14415	COG4122	O-methyltransferase activity
NR984_14420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NR984_14425	COG3906	Belongs to the UPF0473 family
NR984_14430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NR984_14435	COG4472	Bacterial protein of unknown function (DUF965)
NR984_14440	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NR984_14445	COG0628	permease
NR984_14460	COG3881	PFAM PRC-barrel domain
NR984_14465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NR984_14470	COG0457	Tetratricopeptide repeat
NR984_14475	COG0482	sulfurtransferase activity
NR984_14480	COG1104	cysteine desulfurase activity
NR984_14485	COG1959	2 iron, 2 sulfur cluster binding
NR984_14490	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NR984_14495	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NR984_14505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NR984_14510	COG0124	histidyl-tRNA synthetase
NR984_14520	COG3103	Sh3 type 3 domain protein
NR984_14520	COG0860	N-Acetylmuramoyl-L-alanine amidase
NR984_14520	COG4991	sh3 domain protein
NR984_14525	COG1490	D-aminoacyl-tRNA deacylase activity
NR984_14530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NR984_14535	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NR984_14540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NR984_14540	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NR984_14545	COG5416	Lipopolysaccharide assembly protein A domain
NR984_14550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NR984_14550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NR984_14560	COG2244	polysaccharide biosynthetic process
NR984_14565	COG2323	membrane
NR984_14575	COG1862	Preprotein translocase
NR984_14580	COG0343	queuine tRNA-ribosyltransferase activity
NR984_14585	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NR984_14595	COG2255	four-way junction helicase activity
NR984_14600	COG0632	four-way junction helicase activity
NR984_14610	COG2112	serine threonine protein kinase
NR984_14620	COG2318	DinB family
NR984_14625	COG4195	phage-related replication protein
NR984_14640	COG0217	transcriptional regulatory protein
NR984_14650	COG1388	LysM domain
NR984_14655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NR984_14660	COG0157	Belongs to the NadC ModD family
NR984_14665	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NR984_14670	COG1104	cysteine desulfurase activity
NR984_14675	COG1827	regulation of RNA biosynthetic process
NR984_14680	COG0077	Prephenate dehydratase
NR984_14685	COG4492	Belongs to the UPF0735 family
NR984_14690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NR984_14695	COG3290	protein histidine kinase activity
NR984_14700	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NR984_14705	COG2868	ribosomal protein
NR984_14710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NR984_14715	COG1994	Peptidase M50
NR984_14720	COG0739	heme binding
NR984_14725	COG3832	glyoxalase III activity
NR984_14730	COG0640	Transcriptional regulator
NR984_14735	COG2894	cell division
NR984_14740	COG0850	regulation of cytokinetic process
NR984_14745	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NR984_14755	COG1077	Cell shape determining protein MreB Mrl
NR984_14760	COG2003	Belongs to the UPF0758 family
NR984_14765	COG0424	maF-like protein
NR984_14775	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NR984_14780	COG0285	dihydrofolate synthase activity
NR984_14785	COG0525	valine-tRNA ligase activity
NR984_14795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NR984_14800	COG1388	LysM domain
NR984_14805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NR984_14810	COG0113	porphobilinogen synthase activity
NR984_14815	COG1587	Uroporphyrinogen-III synthase
NR984_14820	COG0181	hydroxymethylbilane synthase activity
NR984_14825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NR984_14830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NR984_14840	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NR984_14845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NR984_14850	COG1067	ATP-dependent peptidase activity
NR984_14850	COG0470	DNA polymerase III
NR984_14855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NR984_14860	COG0544	peptidyl-prolyl cis-trans isomerase activity
NR984_14865	COG0457	Tetratricopeptide repeat
NR984_14865	COG1477	protein flavinylation
NR984_14870	COG0066	3-isopropylmalate dehydratase activity
NR984_14875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NR984_14880	COG0473	3-isopropylmalate dehydrogenase activity
NR984_14885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NR984_14890	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NR984_14895	COG0440	acetolactate synthase activity
NR984_14900	COG0028	Belongs to the TPP enzyme family
NR984_14905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NR984_14915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NR984_14935	COG1783	phage Terminase large subunit
NR984_14975	COG5444	nuclease activity
NR984_14980	COG0457	Tetratricopeptide repeat
NR984_15005	COG0622	Phosphoesterase
NR984_15010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NR984_15015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NR984_15020	COG5401	PFAM Sporulation and spore germination
NR984_15025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NR984_15030	COG1846	Transcriptional regulator
NR984_15035	COG2197	response regulator
NR984_15040	COG4221	oxidoreductase activity
NR984_15045	COG0824	Thioesterase
NR984_15050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NR984_15055	COG1053	succinate dehydrogenase
NR984_15060	COG2009	succinate dehydrogenase
NR984_15065	COG1719	4-vinyl reductase, 4VR
NR984_15070	COG0527	aspartate kinase activity
NR984_15075	COG0322	excinuclease ABC activity
NR984_15080	COG3118	belongs to the thioredoxin family
NR984_15085	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NR984_15090	COG2086	electron transfer activity
NR984_15095	COG1024	Enoyl-CoA hydratase
NR984_15100	COG1309	transcriptional regulator
NR984_15105	COG0318	PFAM AMP-dependent synthetase and ligase
NR984_15110	COG3766	membrane
NR984_15115	COG1193	negative regulation of DNA recombination
NR984_15120	COG1796	DNA polymerase
NR984_15120	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NR984_15125	COG1286	toxin biosynthetic process
NR984_15130	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NR984_15135	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NR984_15155	COG1137	ATPase activity
NR984_15170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NR984_15170	COG0072	phenylalanine-tRNA ligase activity
NR984_15175	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NR984_15180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NR984_15190	COG1966	Carbon starvation protein
NR984_15205	COG0395	ABC-type sugar transport system, permease component
NR984_15210	COG1175	transmembrane transport
NR984_15215	COG1653	transport
NR984_15220	COG0371	Dehydrogenase
NR984_15225	COG0235	Class ii aldolase
NR984_15230	COG1069	ribulokinase activity
NR984_15235	COG2160	L-arabinose isomerase activity
NR984_15240	COG3507	Belongs to the glycosyl hydrolase 43 family
NR984_15245	COG1363	Peptidase, m42
NR984_15255	COG3326	Membrane
NR984_15260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NR984_15265	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NR984_15270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NR984_15275	COG1346	cytolysis
NR984_15285	COG3540	Alkaline phosphatase
NR984_15290	COG3279	Response regulator of the LytR AlgR family
NR984_15295	COG3275	phosphorelay sensor kinase activity
NR984_15305	COG1011	Hydrolase
NR984_15310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NR984_15320	COG0398	Pfam SNARE associated Golgi protein
NR984_15325	COG1484	DNA-dependent DNA replication
NR984_15330	COG3611	Membrane attachment protein
NR984_15335	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NR984_15345	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NR984_15350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NR984_15355	COG3866	Pectate lyase
NR984_15360	COG0237	dephospho-CoA kinase activity
NR984_15365	COG1971	Probably functions as a manganese efflux pump
NR984_15370	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NR984_15375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NR984_15375	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NR984_15380	COG5002	protein histidine kinase activity
NR984_15385	COG0745	RESPONSE REGULATOR receiver
NR984_15390	COG0039	L-malate dehydrogenase activity
NR984_15395	COG0538	isocitrate dehydrogenase activity
NR984_15400	COG0372	Belongs to the citrate synthase family
NR984_15405	COG2707	UPF0756 membrane protein
NR984_15410	COG0628	permease
NR984_15415	COG3030	protein affecting phage T7 exclusion by the F plasmid
NR984_15425	COG0205	6-phosphofructokinase activity
NR984_15430	COG0825	malonyl-CoA metabolic process
NR984_15435	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NR984_15440	COG0281	malic enzyme
NR984_15445	COG0587	DNA-directed DNA polymerase activity
NR984_15465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NR984_15475	COG4109	DRTGG domain
NR984_15480	COG1695	Transcriptional regulator
NR984_15485	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NR984_15490	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_15500	COG0165	Argininosuccinate lyase
NR984_15505	COG0137	argininosuccinate synthase activity
NR984_15510	COG0521	Mo-molybdopterin cofactor biosynthetic process
NR984_15515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NR984_15520	COG0827	DNA restriction-modification system
NR984_15525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NR984_15530	COG3874	Sporulation protein YtfJ
NR984_15540	COG1714	RDD family
NR984_15545	COG0616	signal peptide processing
NR984_15550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NR984_15565	COG0477	Major facilitator Superfamily
NR984_15575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NR984_15585	COG0301	tRNA thio-modification
NR984_15590	COG1104	cysteine desulfurase activity
NR984_15595	COG1114	Component of the transport system for branched-chain amino acids
NR984_15605	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NR984_15610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NR984_15615	COG1309	transcriptional regulator
NR984_15620	COG1956	GAF domain-containing protein
NR984_15625	COG2199	diguanylate cyclase activity
NR984_15625	COG2203	Gaf domain
NR984_15630	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NR984_15640	COG3152	Membrane
NR984_15645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NR984_15650	COG1522	sequence-specific DNA binding
NR984_15660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NR984_15665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NR984_15670	COG0454	-acetyltransferase
NR984_15675	COG0517	IMP dehydrogenase activity
NR984_15680	COG0123	including yeast histone deacetylase and acetoin utilization protein
NR984_15685	COG1360	Flagellar Motor Protein
NR984_15690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NR984_15695	COG1609	Transcriptional regulator
NR984_15700	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NR984_15700	COG1605	Chorismate mutase
NR984_15710	COG3118	belongs to the thioredoxin family
NR984_15715	COG4980	gas vesicle protein
NR984_15720	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NR984_15725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NR984_15730	COG1674	ftsk spoiiie
NR984_15735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NR984_15740	COG4848	Belongs to the UPF0354 family
NR984_15745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_15755	COG1363	Peptidase, m42
NR984_15760	COG5584	Small secreted protein
NR984_15765	COG0281	malic enzyme
NR984_15770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NR984_15775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NR984_15785	COG0510	thiamine kinase activity
NR984_15790	COG1523	belongs to the glycosyl hydrolase 13 family
NR984_15795	COG1597	lipid kinase activity
NR984_15805	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NR984_15810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NR984_15825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NR984_15830	COG2252	PERMEase
NR984_15835	COG1349	DNA-binding transcription factor activity
NR984_15840	COG1187	pseudouridine synthase activity
NR984_15845	COG2244	polysaccharide biosynthetic process
NR984_15850	COG2081	HI0933 family
NR984_15855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NR984_15865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NR984_15875	COG0457	Tetratricopeptide repeat
NR984_15885	COG5578	integral membrane protein
NR984_15890	COG0673	inositol 2-dehydrogenase activity
NR984_15895	COG1653	transport
NR984_15900	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
NR984_15905	COG4209	transmembrane transport
NR984_15910	COG2207	Transcriptional regulator
NR984_15915	COG1653	transport
NR984_15920	COG0395	ABC-type sugar transport system, permease component
NR984_15925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NR984_15930	COG1073	alpha beta
NR984_15945	COG0583	DNA-binding transcription factor activity
NR984_15950	COG0346	lactoylglutathione lyase activity
NR984_15955	COG0495	leucyl-tRNA aminoacylation
NR984_15965	COG2814	Major facilitator Superfamily
NR984_15975	COG2433	Pfam Transposase IS66
NR984_15980	COG0577	efflux transmembrane transporter activity
NR984_15985	COG1136	(ABC) transporter
NR984_15995	COG1131	(ABC) transporter
NR984_16000	COG1725	Transcriptional regulator
NR984_16015	COG1242	4 iron, 4 sulfur cluster binding
NR984_16020	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NR984_16025	COG1301	dicarboxylic acid transport
NR984_16035	COG2267	carboxylic ester hydrolase activity
NR984_16040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NR984_16045	COG0671	phosphoesterase, PA-phosphatase related
NR984_16050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NR984_16050	COG0438	transferase activity, transferring glycosyl groups
NR984_16055	COG0367	asparagine synthase
NR984_16060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NR984_16065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NR984_16070	COG1301	dicarboxylic acid transport
NR984_16080	COG1506	peptidase
NR984_16085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NR984_16090	COG1116	anion transmembrane transporter activity
NR984_16095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NR984_16100	COG0494	nUDIX hydrolase
NR984_16110	COG4824	toxin secretion phage lysis holin
NR984_16115	COG0783	Belongs to the Dps family
NR984_16130	COG1854	S-ribosylhomocysteine lyase activity
NR984_16135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NR984_16140	COG0288	reversible hydration of carbon dioxide
NR984_16145	COG0523	cobalamin synthesis protein
NR984_16150	COG0803	Belongs to the bacterial solute-binding protein 9 family
NR984_16155	COG0254	rRNA binding
NR984_16160	COG1271	oxidase subunit
NR984_16165	COG1294	oxidase, subunit
NR984_16180	COG4948	Mandelate Racemase Muconate Lactonizing
NR984_16185	COG0318	PFAM AMP-dependent synthetase and ligase
NR984_16190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NR984_16195	COG0596	Alpha beta hydrolase
NR984_16200	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NR984_16205	COG1169	isochorismate synthase
NR984_16210	COG1575	Belongs to the MenA family. Type 1 subfamily
NR984_16215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NR984_16220	COG0058	SHG alpha-glucan phosphorylase activity
NR984_16225	COG0297	glycogen (starch) synthase activity
NR984_16230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NR984_16235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NR984_16365	COG1609	Transcriptional regulator
NR984_16370	COG3859	Proton-coupled thiamine transporter YuaJ
NR984_16375	COG3764	Sortase (surface protein transpeptidase)
NR984_16390	COG0457	Tetratricopeptide repeat
NR984_16400	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NR984_16405	COG0569	domain protein
NR984_16410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NR984_16420	COG2318	DinB family
NR984_16430	COG1454	alcohol dehydrogenase
NR984_16435	COG1012	belongs to the aldehyde dehydrogenase family
NR984_16440	COG1510	regulation of RNA biosynthetic process
NR984_16450	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NR984_16455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NR984_16460	COG2140	Oxalate decarboxylase
NR984_16470	COG1397	ADP-ribosylglycohydrolase
NR984_16505	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
NR984_16520	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NR984_16525	COG0726	polysaccharide deacetylase
NR984_16530	COG1408	metallophosphoesterase
NR984_16535	COG1968	undecaprenyl-diphosphatase activity
NR984_16540	COG0628	permease
NR984_16545	COG0673	inositol 2-dehydrogenase activity
NR984_16550	COG0693	protein deglycase activity
NR984_16555	COG0840	transmembrane signaling receptor activity
NR984_16560	COG0840	transmembrane signaling receptor activity
NR984_16565	COG0840	transmembrane signaling receptor activity
NR984_16575	COG2070	2-Nitropropane dioxygenase
NR984_16580	COG0432	Pfam Uncharacterised protein family UPF0047
NR984_16585	COG0366	Alpha amylase catalytic
NR984_16600	COG5297	Belongs to the glycosyl hydrolase family 6
NR984_16605	COG1253	flavin adenine dinucleotide binding
NR984_16610	COG2738	Putative neutral zinc metallopeptidase
NR984_16625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NR984_16635	COG2323	membrane
NR984_16640	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
NR984_16650	COG0166	Belongs to the GPI family
NR984_16655	COG1979	alcohol dehydrogenase
NR984_16660	COG2155	Conserved Protein
NR984_16665	COG1098	S1 RNA binding domain
NR984_16670	COG0436	Aminotransferase
NR984_16675	COG1522	sequence-specific DNA binding
NR984_16680	COG2267	carboxylic ester hydrolase activity
NR984_16695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NR984_16710	COG5018	Exonuclease
NR984_16715	COG2814	Major facilitator Superfamily
NR984_16720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NR984_16725	COG3011	Protein conserved in bacteria
NR984_16735	COG3290	protein histidine kinase activity
NR984_16740	COG4565	transcriptional regulatory protein
NR984_16750	COG1183	phosphatidylcholine synthase activity
NR984_16755	COG0586	Pfam SNARE associated Golgi protein
NR984_16760	COG0688	phosphatidylethanolamine metabolic process
NR984_16765	COG3493	citrate carrier protein
NR984_16775	COG2111	Na H antiporter
NR984_16775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NR984_16780	COG2111	Na H antiporter
NR984_16785	COG1006	Multisubunit Na H antiporter MnhC subunit
NR984_16790	COG0651	ATP synthesis coupled electron transport
NR984_16795	COG1863	multisubunit Na H antiporter MnhE subunit
NR984_16800	COG2212	antiporter activity
NR984_16805	COG1320	monovalent cation:proton antiporter activity
NR984_16810	COG2050	protein possibly involved in aromatic compounds catabolism
NR984_16815	COG2197	response regulator
NR984_16820	COG4585	Histidine kinase
NR984_16830	COG0142	geranyltranstransferase activity
NR984_16850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NR984_16855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NR984_16860	COG1335	isochorismatase
NR984_16865	COG5506	Protein of unknown function (DUF1694)
NR984_16880	COG0628	permease
NR984_16885	COG1959	2 iron, 2 sulfur cluster binding
NR984_16890	COG0657	acetylesterase activity
NR984_16900	COG1418	mRNA catabolic process
NR984_16905	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_16915	COG1511	domain protein
NR984_16920	COG1674	ftsk spoiiie
NR984_16920	COG0433	COG0433 Predicted ATPase
NR984_16925	COG4499	WXG100 protein secretion system (Wss), protein YukC
NR984_16930	COG5417	Belongs to the EsaB family
NR984_16935	COG4842	Belongs to the WXG100 family
NR984_16940	COG1115	amino acid carrier protein
NR984_16945	COG2508	Transcriptional regulator
NR984_16945	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NR984_16950	COG0686	Belongs to the AlaDH PNT family
NR984_16960	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NR984_16965	COG1268	BioY protein
NR984_16970	COG2056	Na+-H+ antiporter family
NR984_16975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NR984_16980	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NR984_16985	COG3584	3D domain protein
NR984_17000	COG1252	NADH dehydrogenase
NR984_17005	COG0492	ferredoxin-NADP+ reductase activity
NR984_17020	COG0456	acetyltransferase
NR984_17025	COG0316	Belongs to the HesB IscA family
NR984_17030	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NR984_17035	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NR984_17040	COG4844	belongs to the
NR984_17045	COG1252	NADH dehydrogenase
NR984_17050	COG5646	InterPro IPR014922
NR984_17060	COG0457	Tetratricopeptide repeat
NR984_17065	COG3479	Phenolic acid decarboxylase
NR984_17075	COG4837	Protein of unknown function (DUF1462)
NR984_17090	COG0083	homoserine kinase activity
NR984_17095	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NR984_17100	COG0460	homoserine dehydrogenase
NR984_17110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NR984_17115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NR984_17120	COG0647	UMP catabolic process
NR984_17125	COG2445	Protein of unknown function DUF86
NR984_17130	COG4470	Protein conserved in bacteria
NR984_17145	COG0739	heme binding
NR984_17155	COG0733	neurotransmitter:sodium symporter activity
NR984_17165	COG3377	Domain of unknown function (DUF1805)
NR984_17170	COG0737	Belongs to the 5'-nucleotidase family
NR984_17175	COG0730	response to heat
NR984_17180	COG1801	Protein of unknown function DUF72
NR984_17190	COG3226	Transcriptional regulator
NR984_17200	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NR984_17205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NR984_17210	COG2508	Transcriptional regulator
NR984_17215	COG2814	Major facilitator Superfamily
NR984_17220	COG1288	antiporter activity
NR984_17230	COG2356	endonuclease I
NR984_17240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NR984_17255	COG0457	Tetratricopeptide repeat
NR984_17260	COG0719	Fe-S assembly protein
NR984_17265	COG0822	iron-sulfur transferase activity
NR984_17270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NR984_17275	COG0719	Fe-S assembly protein
NR984_17280	COG0396	ATPase activity
NR984_17290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NR984_17295	COG1464	Belongs to the NlpA lipoprotein family
NR984_17300	COG2011	ABC-type metal ion transport system permease component
NR984_17305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NR984_17315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NR984_17320	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NR984_17330	COG0509	glycine decarboxylation via glycine cleavage system
NR984_17335	COG1393	Belongs to the ArsC family
NR984_17340	COG1960	acyl-CoA dehydrogenase activity
NR984_17345	COG0183	Belongs to the thiolase family
NR984_17350	COG1024	Enoyl-CoA hydratase
NR984_17350	COG1250	3-hydroxyacyl-CoA dehydrogenase
NR984_17365	COG5577	PFAM Coat F domain
NR984_17380	COG1120	ATPase activity
NR984_17385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_17390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_17395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_17410	COG1686	Belongs to the peptidase S11 family
NR984_17415	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_17420	COG0783	Belongs to the Dps family
NR984_17425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NR984_17430	COG0745	RESPONSE REGULATOR receiver
NR984_17435	COG2205	protein histidine kinase activity
NR984_17435	COG2770	Histidine kinase
NR984_17445	COG1309	transcriptional regulator
NR984_17450	COG0114	fumarate hydratase activity
NR984_17460	COG0697	spore germination
NR984_17465	COG0814	amino acid
NR984_17480	COG2197	response regulator
NR984_17485	COG4585	Histidine kinase
NR984_17490	COG4758	membrane
NR984_17500	COG1842	Phage shock protein A
NR984_17505	COG4758	membrane
NR984_17510	COG4677	pectinesterase activity
NR984_17515	COG2096	Adenosyltransferase
NR984_17520	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_17535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NR984_17540	COG1120	ATPase activity
NR984_17545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_17550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_17555	COG1802	Transcriptional regulator
NR984_17560	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_17565	COG2258	MOSC domain
NR984_17570	COG0583	DNA-binding transcription factor activity
NR984_17580	COG2721	sulfolactate sulfo-lyase activity
NR984_17585	COG0246	Mannitol dehydrogenase
NR984_17590	COG1609	Transcriptional regulator
NR984_17595	COG2211	Major facilitator Superfamily
NR984_17600	COG1904	glucuronate isomerase
NR984_17605	COG2205	protein histidine kinase activity
NR984_17610	COG0745	RESPONSE REGULATOR receiver
NR984_17615	COG1120	ATPase activity
NR984_17620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_17630	COG0531	amino acid
NR984_17640	COG1988	membrane-bound metal-dependent
NR984_17645	COG1368	sulfuric ester hydrolase activity
NR984_17650	COG2814	Major facilitator Superfamily
NR984_17655	COG0656	L-ascorbic acid biosynthetic process
NR984_17660	COG1940	carbohydrate kinase activity
NR984_17665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NR984_17675	COG3973	AAA domain
NR984_17680	COG2860	membrane
NR984_17690	COG0456	acetyltransferase
NR984_17695	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NR984_17700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NR984_17705	COG2217	Heavy metal translocating P-type atpase
NR984_17710	COG1653	transport
NR984_17715	COG1175	transmembrane transport
NR984_17720	COG0395	ABC-type sugar transport system, permease component
NR984_17725	COG1501	Belongs to the glycosyl hydrolase 31 family
NR984_17730	COG1472	Belongs to the glycosyl hydrolase 3 family
NR984_17735	COG1121	(ABC) transporter
NR984_17740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NR984_17745	COG0803	Belongs to the bacterial solute-binding protein 9 family
NR984_17760	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NR984_17760	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NR984_17765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_17765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NR984_17765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NR984_17785	COG2217	Heavy metal translocating P-type atpase
NR984_17790	COG2608	mercury ion transmembrane transporter activity
NR984_17795	COG1937	Protein conserved in bacteria
NR984_17800	COG0693	protein deglycase activity
NR984_17805	COG1349	DNA-binding transcription factor activity
NR984_17810	COG1070	Carbohydrate kinase
NR984_17815	COG4952	isomerase
NR984_17825	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_17825	COG3347	Dehydrogenase
NR984_17830	COG2814	Major facilitator Superfamily
NR984_17835	COG2814	Major facilitator Superfamily
NR984_17845	COG2124	cytochrome p450
NR984_17855	COG1846	Transcriptional regulator
NR984_17865	COG0673	inositol 2-dehydrogenase activity
NR984_17870	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NR984_17875	COG1054	Belongs to the UPF0176 family
NR984_17885	COG1191	sigma factor activity
NR984_17895	COG2140	Oxalate decarboxylase
NR984_17940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NR984_17970	COG5444	nuclease activity
NR984_18010	COG5434	Belongs to the glycosyl hydrolase 28 family
NR984_18015	COG1705	Flagellar rod assembly protein muramidase FlgJ
NR984_18025	COG5280	Phage tail tape measure protein TP901
NR984_18025	COG3953	SLT domain
NR984_18085	COG1802	Transcriptional regulator
NR984_18085	COG4626	Terminase
NR984_18240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NR984_18245	COG0557	exoribonuclease II activity
NR984_18250	COG1647	Serine aminopeptidase, S33
NR984_18255	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NR984_18260	COG2002	toxin-antitoxin pair type II binding
NR984_18265	COG1476	TRANSCRIPTIONal
NR984_18270	COG1396	sequence-specific DNA binding
NR984_18275	COG1396	sequence-specific DNA binding
NR984_18280	COG1174	glycine betaine transport
NR984_18285	COG1732	Glycine betaine
NR984_18290	COG1174	glycine betaine transport
NR984_18295	COG0517	IMP dehydrogenase activity
NR984_18295	COG1125	glycine betaine transport
NR984_18300	COG1510	regulation of RNA biosynthetic process
NR984_18305	COG2095	MarC family integral membrane protein
NR984_18310	COG3064	Membrane
NR984_18315	COG4640	response to antibiotic
NR984_18325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_18340	COG0148	phosphopyruvate hydratase activity
NR984_18345	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NR984_18350	COG0149	triose-phosphate isomerase activity
NR984_18355	COG0126	phosphoglycerate kinase activity
NR984_18360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NR984_18365	COG2390	Transcriptional regulator
NR984_18370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NR984_18375	COG1113	amino acid transport
NR984_18395	COG1556	Lactate utilization protein
NR984_18400	COG1139	Iron-sulfur cluster binding protein
NR984_18405	COG0247	lactate metabolic process
NR984_18410	COG2186	Transcriptional regulator
NR984_18415	COG1620	l-lactate permease
NR984_18420	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NR984_18430	COG5039	Polysaccharide pyruvyl transferase
NR984_18435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NR984_18440	COG0110	maltose O-acetyltransferase activity
NR984_18445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NR984_18450	COG2244	polysaccharide biosynthetic process
NR984_18455	COG1216	Glycosyl transferase, family 2
NR984_18460	COG5039	Polysaccharide pyruvyl transferase
NR984_18465	COG1216	Glycosyl transferase, family 2
NR984_18475	COG0438	transferase activity, transferring glycosyl groups
NR984_18480	COG1215	transferase activity, transferring glycosyl groups
NR984_18485	COG0438	transferase activity, transferring glycosyl groups
NR984_18490	COG1086	Polysaccharide biosynthesis protein
NR984_18495	COG0489	protein tyrosine kinase activity
NR984_18500	COG3944	biosynthesis protein
NR984_18505	COG1396	sequence-specific DNA binding
NR984_18515	COG2249	NAD(P)H dehydrogenase (quinone) activity
NR984_18520	COG2271	Major facilitator Superfamily
NR984_18530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NR984_18545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NR984_18555	COG1733	regulation of RNA biosynthetic process
NR984_18560	COG1902	pentaerythritol trinitrate reductase activity
NR984_18565	COG1621	beta-fructofuranosidase activity
NR984_18570	COG1621	beta-fructofuranosidase activity
NR984_18585	COG0740	serine-type endopeptidase activity
NR984_18590	COG1611	Belongs to the LOG family
NR984_18595	COG1694	Mazg nucleotide pyrophosphohydrolase
NR984_18600	COG1078	dGTPase activity
NR984_18605	COG0659	secondary active sulfate transmembrane transporter activity
NR984_18610	COG0288	reversible hydration of carbon dioxide
NR984_18615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NR984_18620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NR984_18625	COG0640	Transcriptional regulator
NR984_18635	COG2732	(Barnase) inhibitor
NR984_18640	COG2162	N-hydroxyarylamine O-acetyltransferase activity
NR984_18645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_18650	COG1481	regulation of sporulation
NR984_18655	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NR984_18660	COG1660	Displays ATPase and GTPase activities
NR984_18665	COG1051	belongs to the nudix hydrolase family
NR984_18670	COG0492	ferredoxin-NADP+ reductase activity
NR984_18675	COG0457	Tetratricopeptide repeat
NR984_18685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NR984_18685	COG0140	phosphoribosyl-ATP diphosphatase activity
NR984_18690	COG0107	imidazoleglycerol-phosphate synthase activity
NR984_18695	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NR984_18700	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NR984_18705	COG0131	Imidazoleglycerol-phosphate dehydratase
NR984_18710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NR984_18715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NR984_18720	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NR984_18725	COG4990	cell redox homeostasis
NR984_18730	COG5297	Belongs to the glycosyl hydrolase family 6
NR984_18735	COG0110	maltose O-acetyltransferase activity
NR984_18740	COG0546	phosphoglycolate phosphatase activity
NR984_18745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NR984_18750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NR984_18755	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NR984_18760	COG1846	Transcriptional regulator
NR984_18765	COG2814	Major facilitator Superfamily
NR984_18770	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NR984_18775	COG1950	PFAM Membrane protein of
NR984_18780	COG1983	PspC domain protein
NR984_18785	COG3595	metallopeptidase activity
NR984_18805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NR984_18810	COG0556	nucleotide-excision repair
NR984_18815	COG4897	Protein conserved in bacteria
NR984_18825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NR984_18835	COG0793	Belongs to the peptidase S41A family
NR984_18835	COG3409	Peptidoglycan-binding domain 1 protein
NR984_18840	COG0473	3-isopropylmalate dehydrogenase activity
NR984_18845	COG0791	NLP P60 protein
NR984_18845	COG3883	PFAM NLP P60 protein
NR984_18850	COG2177	Part of the ABC transporter FtsEX involved in
NR984_18855	COG2884	Cell division ATP-binding protein ftsE
NR984_18860	COG2010	Cytochrome c
NR984_18865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NR984_18875	COG0653	protein targeting
NR984_18880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NR984_18895	COG1516	flagellar protein fliS
NR984_18900	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NR984_18905	COG1334	flagellar protein FlaG
NR984_18910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NR984_18915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NR984_18920	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NR984_18930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NR984_18935	COG1256	bacterial-type flagellum assembly
NR984_18935	COG4786	Flagellar basal body rod
NR984_18940	COG3418	PFAM FlgN family protein
NR984_18945	COG2747	anti-sigma28 factor FlgM
NR984_18955	COG1040	competence protein
NR984_18965	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NR984_18970	COG1307	EDD domain protein, DegV family
NR984_18975	COG2197	response regulator
NR984_18980	COG4585	Histidine kinase
NR984_18985	COG1739	Uncharacterized protein family UPF0029
NR984_18990	COG1316	TRANSCRIPTIONal
NR984_19000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NR984_19005	COG0438	transferase activity, transferring glycosyl groups
NR984_19010	COG1215	transferase activity, transferring glycosyl groups
NR984_19015	COG3206	protein involved in exopolysaccharide biosynthesis
NR984_19020	COG3307	-O-antigen
NR984_19025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NR984_19030	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NR984_19035	COG0297	glycogen (starch) synthase activity
NR984_19035	COG0438	transferase activity, transferring glycosyl groups
NR984_19040	COG2244	polysaccharide biosynthetic process
NR984_19050	COG0860	N-Acetylmuramoyl-L-alanine amidase
NR984_19050	COG2247	cell wall binding repeat
NR984_19055	COG2247	cell wall binding repeat
NR984_19055	COG2385	sporulation resulting in formation of a cellular spore
NR984_19065	COG1316	TRANSCRIPTIONal
NR984_19070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NR984_19075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NR984_19080	COG1134	teichoic acid transport
NR984_19085	COG1682	transport, permease protein
NR984_19090	COG0438	transferase activity, transferring glycosyl groups
NR984_19100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NR984_19120	COG0463	Glycosyl transferase, family 2
NR984_19120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NR984_19125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NR984_19130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NR984_19135	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
NR984_19140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NR984_19145	COG4193	domain, Protein
NR984_19150	COG1482	cell wall glycoprotein biosynthetic process
NR984_19170	COG0800	Aldolase
NR984_19175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NR984_19180	COG1609	Transcriptional regulator
NR984_19185	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NR984_19190	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_19195	COG1063	alcohol dehydrogenase
NR984_19210	COG1316	TRANSCRIPTIONal
NR984_19215	COG0561	phosphatase activity
NR984_19220	COG0791	NLP P60 protein
NR984_19230	COG2843	Capsule synthesis protein
NR984_19240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NR984_19245	COG1609	Transcriptional regulator
NR984_19250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NR984_19255	COG1869	D-ribose catabolic process
NR984_19260	COG1129	ABC transporter
NR984_19265	COG1172	Belongs to the binding-protein-dependent transport system permease family
NR984_19270	COG1879	ABC-type sugar transport system periplasmic component
NR984_19280	COG3527	Alpha-acetolactate decarboxylase
NR984_19285	COG0028	Belongs to the TPP enzyme family
NR984_19290	COG0583	DNA-binding transcription factor activity
NR984_19295	COG0405	Gamma-glutamyltransferase
NR984_19300	COG1522	sequence-specific DNA binding
NR984_19305	COG2059	Chromate
NR984_19310	COG2059	Chromate
NR984_19315	COG4464	protein tyrosine phosphatase activity
NR984_19320	COG3944	biosynthesis protein
NR984_19330	COG4715	Zinc finger, swim domain protein
NR984_19335	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NR984_19345	COG0561	phosphatase activity
NR984_19350	COG1349	DNA-binding transcription factor activity
NR984_19360	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_19370	COG3732	PTS system glucitol sorbitol-specific
NR984_19390	COG0629	single-stranded DNA binding
NR984_19405	COG1970	mechanosensitive ion channel activity
NR984_19410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NR984_19415	COG4786	Flagellar basal body rod
NR984_19420	COG4786	Flagellar basal body rod
NR984_19425	COG1077	Cell shape determining protein MreB Mrl
NR984_19430	COG1609	Transcriptional regulator
NR984_19435	COG1846	Transcriptional regulator
NR984_19440	COG2814	Major facilitator Superfamily
NR984_19445	COG0671	phosphoesterase, PA-phosphatase related
NR984_19450	COG1227	inorganic diphosphatase activity
NR984_19455	COG3546	catalase activity
NR984_19460	COG3361	conserved protein (COG2071)
NR984_19465	COG0517	IMP dehydrogenase activity
NR984_19470	COG0598	Magnesium transport protein CorA
NR984_19475	COG1253	flavin adenine dinucleotide binding
NR984_19480	COG0004	ammonium transporteR
NR984_19485	COG0347	Belongs to the P(II) protein family
NR984_19490	COG0740	serine-type endopeptidase activity
NR984_19500	COG0739	heme binding
NR984_19505	COG1247	-acetyltransferase
NR984_19515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NR984_19520	COG0477	Major facilitator Superfamily
NR984_19525	COG3251	PFAM MbtH domain protein
NR984_19530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NR984_19535	COG1535	isochorismatase
NR984_19535	COG3433	isochorismatase activity
NR984_19540	COG1021	2,3-dihydroxybenzoate-AMP ligase
NR984_19545	COG1169	isochorismate synthase
NR984_19550	COG1028	Short-chain dehydrogenase reductase Sdr
NR984_19555	COG2819	hydrolase of the alpha beta superfamily
NR984_19560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_19565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NR984_19570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_19575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_19575	COG2207	Transcriptional regulator
NR984_19585	COG2910	NAD(P)H-binding
NR984_19590	COG1959	2 iron, 2 sulfur cluster binding
NR984_19600	COG1994	Peptidase M50
NR984_19605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NR984_19610	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NR984_19615	COG2223	nitrite transmembrane transporter activity
NR984_19620	COG3383	formate dehydrogenase (NAD+) activity
NR984_19625	COG2304	oxidoreductase activity
NR984_19630	COG2304	oxidoreductase activity
NR984_19635	COG2385	sporulation resulting in formation of a cellular spore
NR984_19640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NR984_19650	COG4836	Membrane
NR984_19655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NR984_19660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NR984_19665	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NR984_19670	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NR984_19675	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NR984_19680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NR984_19685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NR984_19700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NR984_19705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NR984_19710	COG4475	Protein of unknown function (DUF436)
NR984_19715	COG0698	ribose 5-phosphate isomerase
NR984_19720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NR984_19725	COG1971	Probably functions as a manganese efflux pump
NR984_19730	COG0009	L-threonylcarbamoyladenylate synthase
NR984_19735	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NR984_19745	COG0738	Major facilitator superfamily
NR984_19755	COG0561	phosphatase activity
NR984_19760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NR984_19765	COG1609	Transcriptional regulator
NR984_19770	COG2890	protein-(glutamine-N5) methyltransferase activity
NR984_19775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NR984_19780	COG0346	lactoylglutathione lyase activity
NR984_19785	COG0789	Transcriptional regulator
NR984_19790	COG0679	Auxin Efflux Carrier
NR984_19795	COG0281	malic enzyme
NR984_19800	COG1435	thymidine kinase activity
NR984_19805	COG0254	rRNA binding
NR984_19810	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NR984_19815	COG1494	fructose-1,6-bisphosphatase
NR984_19820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NR984_19825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NR984_19830	COG0191	fructose-bisphosphate aldolase activity
NR984_19835	COG2204	response regulator
NR984_19840	COG4821	SIS domain
NR984_19845	COG0504	CTP synthase activity
NR984_19850	COG3343	RNA polymerase activity
NR984_19860	COG1960	acyl-CoA dehydrogenase activity
NR984_19865	COG1960	acyl-CoA dehydrogenase activity
NR984_19870	COG1250	3-hydroxyacyl-CoA dehydrogenase
NR984_19875	COG0183	Belongs to the thiolase family
NR984_19880	COG0247	lactate metabolic process
NR984_19880	COG2181	nitrate reductase activity
NR984_19885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NR984_19895	COG0018	arginyl-trna synthetase
NR984_19900	COG4506	Protein conserved in bacteria
NR984_19905	COG0010	Belongs to the arginase family
NR984_19910	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NR984_19925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NR984_19935	COG1994	Peptidase M50
NR984_19940	COG1942	4-Oxalocrotonate Tautomerase
NR984_19950	COG3465	dGTPase activity
NR984_19955	COG1078	dGTPase activity
NR984_19960	COG4844	belongs to the
NR984_19985	COG2814	Major facilitator Superfamily
NR984_20010	COG1414	Transcriptional regulator
NR984_20020	COG0280	phosphate acetyltransferase
NR984_20025	COG3253	May function as heme-dependent peroxidase
NR984_20035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NR984_20055	COG1131	(ABC) transporter
NR984_20070	COG2363	Small membrane protein
NR984_20075	COG2233	PERMEase
NR984_20085	COG1012	belongs to the aldehyde dehydrogenase family
NR984_20090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NR984_20095	COG1216	Glycosyl transferase, family 2
NR984_20100	COG0351	phosphomethylpyrimidine kinase
NR984_20110	COG1621	beta-fructofuranosidase activity
NR984_20115	COG1263	PTS System
NR984_20115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_20120	COG3711	transcriptional antiterminator
NR984_20130	COG1404	Belongs to the peptidase S8 family
NR984_20140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NR984_20145	COG0778	Nitroreductase
NR984_20155	COG0772	Belongs to the SEDS family
NR984_20160	COG0772	Belongs to the SEDS family
NR984_20165	COG3314	Sporulation integral membrane protein YlbJ
NR984_20180	COG0456	acetyltransferase
NR984_20215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NR984_20225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NR984_20230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NR984_20235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NR984_20250	COG3162	membrane
NR984_20255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NR984_20265	COG2115	Belongs to the xylose isomerase family
NR984_20275	COG0352	thiamine-phosphate diphosphorylase activity
NR984_20280	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NR984_20285	COG0583	DNA-binding transcription factor activity
NR984_20300	COG1380	Effector of murein hydrolase LrgA
NR984_20305	COG1346	cytolysis
NR984_20315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NR984_20320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NR984_20325	COG0346	lactoylglutathione lyase activity
NR984_20330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NR984_20335	COG1442	glycosyl transferase family 8
NR984_20350	COG4585	Histidine kinase
NR984_20355	COG2197	response regulator
NR984_20360	COG2409	Drug exporters of the RND superfamily
NR984_20365	COG5522	Integral membrane protein (intg_mem_TP0381)
NR984_20370	COG2271	Major facilitator Superfamily
NR984_20375	COG4948	Mandelate Racemase Muconate Lactonizing
NR984_20380	COG0800	Aldolase
NR984_20385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NR984_20395	COG2234	aminopeptidase activity
NR984_20400	COG0477	Major facilitator Superfamily
NR984_20410	COG2357	RelA SpoT domain protein
NR984_20425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NR984_20430	COG1696	Membrane protein involved in D-alanine export
NR984_20435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NR984_20440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NR984_20445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NR984_20450	COG2814	Major facilitator Superfamily
NR984_20455	COG1486	melibiose metabolic process
NR984_20460	COG1447	Phosphotransferase system cellobiose-specific component IIA
NR984_20465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NR984_20470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NR984_20475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NR984_20475	COG3711	transcriptional antiterminator
NR984_20485	COG2094	Belongs to the DNA glycosylase MPG family
NR984_20495	COG0372	Belongs to the citrate synthase family
NR984_20500	COG2079	MmgE PrpD family protein
NR984_20505	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NR984_20520	COG1132	(ABC) transporter
NR984_20525	COG2755	lipolytic protein G-D-S-L family
NR984_20540	COG2814	Major facilitator Superfamily
NR984_20545	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NR984_20550	COG1131	(ABC) transporter
NR984_20570	COG1595	DNA-templated transcription, initiation
NR984_20575	COG2814	Major facilitator Superfamily
NR984_20580	COG0753	catalase activity
NR984_20585	COG0753	catalase activity
NR984_20590	COG0735	belongs to the Fur family
NR984_20595	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NR984_20600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
NR984_20605	COG1131	(ABC) transporter
NR984_20620	COG1131	(ABC) transporter
NR984_20675	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NR984_20680	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NR984_20685	COG4988	ABC transporter
NR984_20690	COG1294	oxidase, subunit
NR984_20695	COG1271	oxidase subunit
NR984_20700	COG2116	formate transmembrane transporter activity
NR984_20710	COG0281	malic enzyme
NR984_20715	COG1757	Na H antiporter
NR984_20720	COG1027	Aspartate ammonia-lyase
NR984_20725	COG0252	asparaginase activity
NR984_20730	COG1396	sequence-specific DNA binding
NR984_20735	COG2706	6-phosphogluconolactonase activity
NR984_20745	COG2205	protein histidine kinase activity
NR984_20750	COG1136	(ABC) transporter
NR984_20760	COG5294	Protein conserved in bacteria
NR984_20775	COG0726	polysaccharide deacetylase
NR984_20780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NR984_20785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NR984_20790	COG1215	transferase activity, transferring glycosyl groups
NR984_20795	COG3493	citrate carrier protein
NR984_20800	COG0584	glycerophosphoryl diester phosphodiesterase
NR984_20815	COG1368	sulfuric ester hydrolase activity
NR984_20825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NR984_20840	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NR984_20850	COG0549	Belongs to the carbamate kinase family
NR984_20860	COG2723	6-phospho-beta-galactosidase activity
NR984_20865	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NR984_20875	COG1595	DNA-templated transcription, initiation
NR984_20900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NR984_20905	COG2195	Cleaves the N-terminal amino acid of tripeptides
NR984_20910	COG1621	beta-fructofuranosidase activity
NR984_20915	COG2223	nitrite transmembrane transporter activity
NR984_20920	COG0395	ABC-type sugar transport system, permease component
NR984_20925	COG1175	transmembrane transport
NR984_20935	COG1609	Transcriptional regulator
NR984_20950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NR984_20955	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NR984_20960	COG0463	Glycosyl transferase, family 2
NR984_20965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NR984_20990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NR984_21005	COG2723	6-phospho-beta-galactosidase activity
NR984_21010	COG2190	(PTS) system
NR984_21010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_21010	COG1263	PTS System
NR984_21015	COG3711	transcriptional antiterminator
NR984_21020	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NR984_21025	COG1122	ATPase activity
NR984_21030	COG4721	ABC-type cobalt transport system, permease component
NR984_21035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NR984_21045	COG2224	Isocitrate lyase
NR984_21050	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NR984_21060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NR984_21065	COG0577	efflux transmembrane transporter activity
NR984_21070	COG1136	(ABC) transporter
NR984_21075	COG2205	protein histidine kinase activity
NR984_21080	COG0745	RESPONSE REGULATOR receiver
NR984_21085	COG2723	6-phospho-beta-galactosidase activity
NR984_21090	COG2190	(PTS) system
NR984_21090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_21090	COG1263	PTS System
NR984_21100	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NR984_21115	COG3507	Belongs to the glycosyl hydrolase 43 family
NR984_21120	COG0513	Belongs to the DEAD box helicase family
NR984_21150	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NR984_21155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NR984_21160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NR984_21165	COG2390	Transcriptional regulator
NR984_21175	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
NR984_21180	COG3706	GGDEF domain
NR984_21185	COG5298	Protein conserved in bacteria
NR984_21200	COG3977	Valine--pyruvate aminotransferase
NR984_21215	COG1181	Belongs to the D-alanine--D-alanine ligase family
NR984_21225	COG0191	fructose-bisphosphate aldolase activity
NR984_21230	COG1082	Xylose isomerase domain protein TIM barrel
NR984_21235	COG1082	Xylose isomerase domain protein TIM barrel
NR984_21240	COG0673	inositol 2-dehydrogenase activity
NR984_21245	COG2814	Major facilitator Superfamily
NR984_21250	COG1082	Xylose isomerase domain protein TIM barrel
NR984_21255	COG3962	Belongs to the TPP enzyme family
NR984_21260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NR984_21265	COG3718	enzyme involved in inositol metabolism
NR984_21270	COG1012	belongs to the aldehyde dehydrogenase family
NR984_21275	COG1349	DNA-binding transcription factor activity
NR984_21280	COG0667	Aldo Keto reductase
NR984_21285	COG0584	glycerophosphoryl diester phosphodiesterase
NR984_21290	COG2271	Major facilitator Superfamily
NR984_21295	COG0326	Molecular chaperone. Has ATPase activity
NR984_21300	COG0488	(ABC) transporter
NR984_21305	COG0561	phosphatase activity
NR984_21325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NR984_21355	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NR984_21360	COG0577	efflux transmembrane transporter activity
NR984_21365	COG1136	(ABC) transporter
NR984_21370	COG2205	protein histidine kinase activity
NR984_21375	COG0745	RESPONSE REGULATOR receiver
NR984_21385	COG0840	transmembrane signaling receptor activity
NR984_21385	COG5278	phosphoserine phosphatase activity
NR984_21390	COG1115	amino acid carrier protein
NR984_21395	COG0686	Belongs to the AlaDH PNT family
NR984_21400	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NR984_21405	COG1874	Beta-galactosidase
NR984_21410	COG3833	ABC-type maltose transport systems, permease component
NR984_21415	COG1175	transmembrane transport
NR984_21420	COG2182	Extracellular solute-binding protein
NR984_21425	COG1609	Transcriptional regulator
NR984_21440	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NR984_21445	COG1940	carbohydrate kinase activity
NR984_21470	COG1012	belongs to the aldehyde dehydrogenase family
NR984_21470	COG1454	alcohol dehydrogenase
NR984_21475	COG0450	alkyl hydroperoxide reductase
NR984_21480	COG3634	alkyl hydroperoxide reductase activity
NR984_21505	COG1131	(ABC) transporter
NR984_21515	COG4585	Histidine kinase
NR984_21520	COG2197	response regulator
NR984_21550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NR984_21565	COG0456	acetyltransferase
NR984_21580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NR984_21585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NR984_21590	COG4853	Protein conserved in bacteria
NR984_21595	COG4863	YycH protein
NR984_21600	COG5002	protein histidine kinase activity
NR984_21605	COG0745	RESPONSE REGULATOR receiver
NR984_21630	COG1051	belongs to the nudix hydrolase family
NR984_21635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NR984_21645	COG0305	Participates in initiation and elongation during chromosome replication
NR984_21660	COG3093	addiction module antidote protein HigA
NR984_21665	COG2807	transmembrane transport
NR984_21670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NR984_21675	COG0363	glucosamine-6-phosphate deaminase activity
NR984_21680	COG2188	Transcriptional regulator
NR984_21685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NR984_21690	COG1263	PTS System
NR984_21690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NR984_21695	COG0359	binds to the 23S rRNA
NR984_21700	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NR984_21705	COG4241	membrane
NR984_21715	COG5577	PFAM Coat F domain
NR984_21720	COG0589	response to stress
NR984_21725	COG0659	secondary active sulfate transmembrane transporter activity
NR984_21730	COG2271	Major facilitator Superfamily
NR984_21735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NR984_21740	COG0629	single-stranded DNA binding
NR984_21745	COG0360	Binds together with S18 to 16S ribosomal RNA
NR984_21750	COG0012	GTP binding
NR984_21755	COG4481	Protein conserved in bacteria
NR984_21760	COG3949	Membrane
NR984_21770	COG1475	DNA binding
NR984_21775	COG1192	Involved in chromosome partitioning
NR984_21780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NR984_21790	COG1475	DNA binding
NR984_21795	COG0357	Ribosomal RNA small subunit methyltransferase G
NR984_21800	COG0445	tRNA wobble uridine modification
NR984_21805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NR984_21810	COG1847	R3H domain protein
NR984_21815	COG0706	membrane insertase activity
NR984_21820	COG0594	ribonuclease P activity