locus-tag class description EKQ63_00015 ENOG4107QJE Chromosome Partitioning Protein EKQ63_00055 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EKQ63_00065 ENOG4105RYY domain protein EKQ63_00070 ENOG4108IBT Inherit from COG: transposase EKQ63_00140 ENOG41060SN EKQ63_00170 ENOG4106CGH Phage Mu protein F like protein EKQ63_00175 ENOG4108MDF Phage Portal Protein EKQ63_00215 ENOG4108C33 Resolvase EKQ63_00230 ENOG4108UI2 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity) EKQ63_00245 ENOG4108Z1K This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) EKQ63_00275 ENOG4105DVF Cytosine-specific methyltransferase EKQ63_00280 ENOG4106CVF DNA replication protein EKQ63_00285 ENOG4105YQ0 EKQ63_00330 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin EKQ63_00420 ENOG4105ECI YeeC-like protein EKQ63_00425 ENOG4105F6A helicase EKQ63_00430 ENOG4105D85 methylase EKQ63_00465 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EKQ63_00470 ENOG4108594 Permease of the drug metabolite transporter EKQ63_00480 ENOG410780I phosphoprotein phosphatase activity EKQ63_00705 ENOG4105K4H Nlp p60 protein EKQ63_00785 ENOG4105C9U ATP-dependent DNA helicase RecQ EKQ63_00820 ENOG4108IYT Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EKQ63_00845 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EKQ63_00870 ENOG4108J59 Extracellular solute-binding protein, family 5 EKQ63_00915 ENOG4107QJE Chromosome Partitioning Protein EKQ63_00940 ENOG4105K8R UPF0145 protein EKQ63_00955 ENOG4105EWC Purine nucleoside phosphorylase EKQ63_00970 ENOG4105K8R UPF0145 protein EKQ63_00990 ENOG4108Q5U germination protein, ger(x)c family EKQ63_00995 ENOG4105E1K spore germination protein EKQ63_01040 ENOG41088CC tellurite resistance protein tehB EKQ63_01345 ENOG4108U4N (sortase) family EKQ63_01370 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) EKQ63_01375 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) EKQ63_01405 ENOG4105C5Y PTS System EKQ63_01435 ENOG4105D4Y metalloprotease EKQ63_01450 ENOG4108K8K Transcriptional regulator EKQ63_01455 ENOG4105DCF alanine dehydrogenase EKQ63_01460 ENOG4107VMI polysaccharide deacetylase EKQ63_01470 ENOG4105EXC Acyl-transferase EKQ63_01500 ENOG4105DHH glycosyltransferase MGT family EKQ63_01505 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EKQ63_01510 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EKQ63_01515 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EKQ63_01525 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EKQ63_01545 ENOG4108UHE carbonic anhydrase EKQ63_01565 ENOG4108MRH transcriptional regulatory protein EKQ63_01580 ENOG4105CH6 catalase EKQ63_01600 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_01635 ENOG4108B31 Spore germination protein EKQ63_01645 ENOG4105CUB amino acid EKQ63_01680 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) EKQ63_01690 ENOG4105C19 ABC transporter EKQ63_01710 ENOG4107ZTW SNARE associated Golgi EKQ63_01745 ENOG4105EWC Purine nucleoside phosphorylase EKQ63_01770 ENOG4105BZU Histidine kinase EKQ63_01785 ENOG4105VMP Transcriptional regulator EKQ63_01795 ENOG4105CJ1 ABC, transporter EKQ63_01805 ENOG4105NX3 Membrane EKQ63_01840 ENOG4105G7B Protein of unknown function (DUF2992) EKQ63_01860 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EKQ63_01895 ENOG4105ZMH deoxynucleoside kinase EKQ63_01905 ENOG4105GTG Isochorismatase EKQ63_01910 ENOG4108Z6B deaminase EKQ63_01920 ENOG4105C6E dna polymerase iii EKQ63_01940 ENOG41067KS pro-sigma K processing EKQ63_01955 ENOG4105CXN decarboxylase EKQ63_01965 ENOG4105FA2 dna polymerase iii EKQ63_01970 ENOG4105MA4 psp1 domain protein EKQ63_01980 ENOG41060K3 Methyltransferase EKQ63_01990 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EKQ63_01995 ENOG4105KRN Transcriptional regulator, abrb family EKQ63_02005 ENOG4105F8V Hydrolase, tatD family EKQ63_02010 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) EKQ63_02020 ENOG4105XFA sporulation peptidase YabG EKQ63_02025 ENOG4105W42 Veg protein EKQ63_02040 ENOG4105DFT pur operon repressor EKQ63_02045 ENOG4105KME endoribonuclease L-psp EKQ63_02060 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EKQ63_02075 ENOG4108JA2 transcriptioN-repair coupling factor EKQ63_02080 ENOG4108M14 stage v sporulation protein t EKQ63_02090 ENOG4108IY2 MazG family EKQ63_02095 ENOG41082I2 s4 domain protein EKQ63_02100 ENOG4105VYY sporulation protein yabp EKQ63_02115 ENOG41060GV RNA binding s1 domain protein EKQ63_02140 ENOG4108UGV hypoxanthine phosphoribosyltransferase EKQ63_02145 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EKQ63_02160 ENOG4105C6T cysteine synthase EKQ63_02165 ENOG4105CRQ synthase (Component I) EKQ63_02170 ENOG4105DDQ anthranilate synthase EKQ63_02175 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 EKQ63_02180 ENOG4105EEI dihydropteroate synthase EKQ63_02185 ENOG4105KRF dihydroneopterin aldolase EKQ63_02190 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EKQ63_02200 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EKQ63_02225 ENOG4108Z0C Uvrb UvrC protein EKQ63_02240 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EKQ63_02250 ENOG4105CTP PilT protein domain protein EKQ63_02270 ENOG4105D7W serine acetyltransferase EKQ63_02285 ENOG4105C2N RNA methyltransferase TrmH family group 3 EKQ63_02290 ENOG4105M0M Tetracycline resistance protein EKQ63_02295 ENOG4105QIV RNA polymerase EKQ63_02310 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EKQ63_02335 ENOG4107Y49 methyltransferase EKQ63_02350 ENOG4105XPM ribosomal protein EKQ63_02460 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) EKQ63_02485 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EKQ63_02495 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EKQ63_02505 ENOG41067V7 50S ribosomal protein L36 EKQ63_02540 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) EKQ63_02570 ENOG4105D1F ATP-binding protein EKQ63_02585 ENOG4108NMV polysaccharide deacetylase EKQ63_02660 ENOG4105C8B TIGR00159 family EKQ63_02665 ENOG4107U5W ybbr family EKQ63_02685 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein EKQ63_02705 ENOG4108PSK reductase EKQ63_02710 ENOG4108UMI ABC transporter, permease EKQ63_02715 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EKQ63_02720 ENOG4105D01 (LipO)protein EKQ63_02725 ENOG4105CPQ Dehydrogenase EKQ63_02735 ENOG4105IQ5 FAD linked oxidase domain protein EKQ63_02750 ENOG4105C2C drug resistance transporter, Bcr CflA EKQ63_02765 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EKQ63_02770 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EKQ63_02775 ENOG4105C3U ABC transporter EKQ63_02780 ENOG4108JQ7 (ABC) transporter EKQ63_02805 ENOG4105U5Y Transcriptional regulator EKQ63_02815 ENOG4108J59 Extracellular solute-binding protein, family 5 EKQ63_02820 ENOG4108J59 Extracellular solute-binding protein, family 5 EKQ63_02835 ENOG4107XDY Nicotinamide Mononucleotide Transporter EKQ63_02845 ENOG4105E0C molybdate abc transporter EKQ63_02850 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EKQ63_02855 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family EKQ63_02885 ENOG4105F6E Acyl-transferase EKQ63_02905 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) EKQ63_02915 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) EKQ63_02935 ENOG4105C5H ABC transporter EKQ63_02940 ENOG4105BZU Histidine kinase EKQ63_02945 ENOG4105WH1 Two component transcriptional regulator luxr family EKQ63_02950 ENOG4105CJ1 ABC, transporter EKQ63_02955 ENOG41090VJ ABC-2 type transporter EKQ63_02960 ENOG4108KYE ABC-2 type transporter EKQ63_02970 ENOG4105DEF Extracellular solute-binding protein, family 5 EKQ63_02975 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein EKQ63_02985 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EKQ63_02990 ENOG4105C3U ABC transporter EKQ63_02995 ENOG4108JQ7 (ABC) transporter EKQ63_03000 ENOG410667J hydrolase EKQ63_03030 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase EKQ63_03035 ENOG4105ERH Fumarylacetoacetate hydrolase EKQ63_03045 ENOG4105CUB amino acid EKQ63_03050 ENOG4108SC4 )-transporter EKQ63_03055 ENOG4105CPF Cell wall formation (By similarity) EKQ63_03060 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) EKQ63_03085 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein EKQ63_03090 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EKQ63_03100 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) EKQ63_03180 ENOG4105K8N protein family UPF0079, ATPase EKQ63_03185 ENOG41072GX Peptidase M22 Glycoprotease EKQ63_03190 ENOG410801F ribosomal-protein-alanine acetyltransferase EKQ63_03200 ENOG4105C5H ABC transporter EKQ63_03215 ENOG4108TYN CAAX amino terminal protease family protein EKQ63_03235 ENOG4105C7N Xanthine uracil vitamin C permease EKQ63_03245 ENOG4105BZU Histidine kinase EKQ63_03255 ENOG4107ZXU DSBA oxidoreductase EKQ63_03300 ENOG4108SHN Glycosyl transferase, family 2 EKQ63_03310 ENOG4105SX7 Transporter EKQ63_03330 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EKQ63_03335 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EKQ63_03340 ENOG4105C83 adenylosuccinate lyase EKQ63_03350 ENOG4105VR9 phosphoribosylformylglycinamidine synthase EKQ63_03375 ENOG4108V3E phosphoribosylglycinamide formyltransferase EKQ63_03390 ENOG4105C12 Phosphoribosylglycinamide synthetase EKQ63_03420 ENOG4105C4R Atp-dependent dna helicase EKQ63_03445 ENOG4108W2Y isochorismatase EKQ63_03455 ENOG4108UMI ABC transporter, permease EKQ63_03460 ENOG4105D01 (LipO)protein EKQ63_03480 ENOG410834F Transcriptional regulator EKQ63_03485 ENOG4107I77 yiaA/B two helix domain EKQ63_03505 ENOG4105CBD Diacylglycerol kinase EKQ63_03510 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EKQ63_03515 ENOG4108JPW Aminotransferase EKQ63_03525 ENOG4105C26 Dehydrogenase EKQ63_03530 ENOG4105KPY Small multidrug resistance protein EKQ63_03545 ENOG4105D9N nucleoside EKQ63_03550 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) EKQ63_03560 ENOG4105BZU Histidine kinase EKQ63_03565 ENOG4105C7K acetolactate synthase EKQ63_03575 ENOG4108W15 Protein of unknown function (DUF1456) EKQ63_03590 ENOG4105DTQ mandelate racemase muconate lactonizing EKQ63_03600 ENOG4105DFD Na H antiporter EKQ63_03625 ENOG4105D3R alkyl hydroperoxide reductase EKQ63_03630 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) EKQ63_03640 ENOG4107W7X Aldolase EKQ63_03645 ENOG4105EHG Permease protein EKQ63_03650 ENOG4105DQ5 transport system permease protein EKQ63_03655 ENOG4108V5C ABC transporter EKQ63_03685 ENOG4106UIA EKQ63_03690 ENOG4106UIA EKQ63_03725 ENOG410756H nucleotidyltransferase EKQ63_03730 ENOG4105D2S major facilitator superfamily EKQ63_03745 ENOG4105E5Q amino acid AbC transporter EKQ63_03750 ENOG4105EAB amino acid AbC transporter EKQ63_03760 ENOG4105C8Q Methyl-accepting chemotaxis EKQ63_03775 ENOG4105DBV ornithine carbamoyltransferase EKQ63_03785 ENOG4105C5B carbamate kinase EKQ63_03790 ENOG4108W63 CRP FNR family transcriptional regulator EKQ63_03800 ENOG4105DNP FAD linked oxidase domain protein EKQ63_03810 ENOG4105CI1 PTS System EKQ63_03845 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter EKQ63_03860 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component EKQ63_03880 ENOG4105C5H ABC transporter EKQ63_03915 ENOG41062JF Transcriptional regulator EKQ63_03935 ENOG4105DEU major facilitator superfamily EKQ63_03965 ENOG4108N0M stress protein EKQ63_03970 ENOG4106FN3 tellurium resistance protein EKQ63_03975 ENOG4106FN3 tellurium resistance protein EKQ63_03980 ENOG4107TS3 membrane protein, TerC EKQ63_03985 ENOG4108TTB tellurium resistance protein EKQ63_04005 ENOG4105KJF protein tyrosine phosphatase EKQ63_04015 ENOG4107U9T Pfam:Ribonuclease_BN EKQ63_04020 ENOG4105C59 p-type ATPase EKQ63_04025 ENOG4108IPJ Membrane EKQ63_04040 ENOG4105C3F Signal peptidase i EKQ63_04050 ENOG4107ZTW SNARE associated Golgi EKQ63_04065 ENOG410606W general stress protein EKQ63_04070 ENOG4105UPD Calcium Proton EKQ63_04120 ENOG4108JUB Transcriptional regulator EKQ63_04130 ENOG4108IQI permease EKQ63_04155 ENOG4105CSV Glutaminase EKQ63_04165 ENOG4108A04 Beta-lactamase EKQ63_04185 ENOG4105CKK Glycosyl transferase, family 2 EKQ63_04190 ENOG4107QQG Dehydrogenase EKQ63_04195 ENOG4105C3I Nad-dependent epimerase dehydratase EKQ63_04210 ENOG4105F1A Pyruvate formate-lyase EKQ63_04230 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) EKQ63_04235 ENOG4105ECP epimerase EKQ63_04240 ENOG4105D7V transposase EKQ63_04270 ENOG41067AE Membrane-bound metal-dependent hydrolase EKQ63_04275 ENOG4105CEN a g-specific adenine glycosylase EKQ63_04280 ENOG4106BXE EKQ63_04300 ENOG4105BZ1 (ABC) transporter EKQ63_04305 ENOG4107NBY Membrane EKQ63_04310 ENOG4105CBC glutamate synthase EKQ63_04320 ENOG4108IUW ABC transporter EKQ63_04340 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EKQ63_04345 ENOG4105G5W regulator Fur family EKQ63_04455 ENOG4108JQC penicillin-binding protein 1A EKQ63_04460 ENOG4107ZQN disulfide bond EKQ63_04470 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EKQ63_04480 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EKQ63_04485 ENOG4105BZU Histidine kinase EKQ63_04490 ENOG4105CYN Serine protein kinase EKQ63_04510 ENOG4105C94 Transporter EKQ63_04525 ENOG4105DZ6 Band 7 protein EKQ63_04535 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism EKQ63_04540 ENOG4108V9W transcriptional regulatory protein EKQ63_04545 ENOG4105D4T Citrate transporter EKQ63_04575 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator EKQ63_04580 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EKQ63_04585 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component EKQ63_04590 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component EKQ63_04595 ENOG4105BZ7 extracellular solute-binding protein family 1 EKQ63_04600 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) EKQ63_04605 ENOG4108STX response regulator EKQ63_04610 ENOG4105US7 Histidine kinase EKQ63_04635 ENOG4108MRH transcriptional regulatory protein EKQ63_04645 ENOG4105C6K Malic enzyme EKQ63_04655 ENOG4108UZ3 Transporter EKQ63_04660 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EKQ63_04670 ENOG4105BZU Histidine kinase EKQ63_04675 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_04680 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) EKQ63_04685 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EKQ63_04690 ENOG4108JB9 formate dehydrogenase EKQ63_04710 ENOG4105CUB amino acid EKQ63_04720 ENOG4105C59 p-type ATPase EKQ63_04730 ENOG4105DAP Nicotinate phosphoribosyltransferase EKQ63_04760 ENOG41073R8 VanW family EKQ63_04765 ENOG4108KGH TRANSCRIPTIONal EKQ63_04770 ENOG4105D9N nucleoside EKQ63_04775 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase EKQ63_04780 ENOG4105C37 (CBS) domain EKQ63_04785 ENOG4108IJ0 Aspartate ammonia-lyase EKQ63_04790 ENOG4105DAA L-lactate EKQ63_04805 ENOG4105DUX Transporter EKQ63_04810 ENOG4108MES Periplasmic binding protein EKQ63_04815 ENOG4105DQ5 transport system permease protein EKQ63_04820 ENOG4108IHU transport system permease protein EKQ63_04825 ENOG4105E0A ABC, transporter EKQ63_04840 ENOG4105EXW epimerase dehydratase EKQ63_04845 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) EKQ63_04855 ENOG4107T89 von Willebrand factor, type A EKQ63_04860 ENOG4105GMT ATPase associated with various cellular activities aaa_5 EKQ63_04865 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EKQ63_04885 ENOG4105D5Q Arginine ornithine antiporter EKQ63_04890 ENOG4107414 GntR family transcriptional regulator EKQ63_04895 ENOG4105C5Y PTS System EKQ63_04900 ENOG4105CG3 alpha amylase, catalytic region EKQ63_04915 ENOG4105E1K spore germination protein EKQ63_04925 ENOG4105CRN Aminoglycoside phosphotransferase EKQ63_04930 ENOG4105BZG amino acid carrier protein EKQ63_04935 ENOG4105CDA abc transporter atp-binding protein EKQ63_04940 ENOG4105CT1 (ABC) transporter EKQ63_04945 ENOG4105EAD ABC transporter EKQ63_04950 ENOG4105DRP amino acid AbC transporter EKQ63_04955 ENOG4108IQI permease EKQ63_04980 ENOG4105D29 Helix-turn-helix type 11 domain protein EKQ63_04985 ENOG4105NAE bifunctional deaminase-reductase domain protein EKQ63_04990 ENOG4105BZU Histidine kinase EKQ63_05005 ENOG4105CHH sulfate transporter EKQ63_05010 ENOG41068KF Universal stress protein EKQ63_05020 ENOG4108J59 Extracellular solute-binding protein, family 5 EKQ63_05030 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EKQ63_05035 ENOG4108JQ7 (ABC) transporter EKQ63_05045 ENOG4105CXY transporter EKQ63_05050 ENOG41067TZ transcriptional regulator, MarR family EKQ63_05055 ENOG4105C0R drug resistance transporter emrb qaca subfamily EKQ63_05060 ENOG4105ETE Transcriptional regulator (LacI family EKQ63_05065 ENOG4108RVA ribokinase EKQ63_05075 ENOG4105C2J ABC transporter EKQ63_05080 ENOG4105CNN ABC, transporter EKQ63_05085 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EKQ63_05090 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EKQ63_05150 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer EKQ63_05155 ENOG41069ER domain protein EKQ63_05160 ENOG4105VZ8 Transcriptional regulator EKQ63_05165 ENOG4107D63 EKQ63_05175 ENOG4105DUX Transporter EKQ63_05195 ENOG4105C85 amino acid EKQ63_05200 ENOG4105C7N Xanthine uracil vitamin C permease EKQ63_05215 ENOG4105MA6 gCN5-related N-acetyltransferase EKQ63_05235 ENOG4105CCU oxidase (Subunit III) EKQ63_05240 ENOG4105BZ9 Cytochrome C oxidase, subunit I EKQ63_05245 ENOG4105E2S oxidase) subunit II EKQ63_05265 ENOG4106CAD Protein of unknown function (DUF3311) EKQ63_05270 ENOG4105E1V na solute symporter EKQ63_05285 ENOG4108NHD germination protein EKQ63_05290 ENOG4105CE1 Ferrous iron transport protein b EKQ63_05295 ENOG4105CE1 Ferrous iron transport protein b EKQ63_05300 ENOG4105CE1 Ferrous iron transport protein b EKQ63_05305 ENOG4105CVA phosphate EKQ63_05310 ENOG4105C8U phosphate abc transporter EKQ63_05315 ENOG4105E2Z phosphate ABC transporter (Permease EKQ63_05365 ENOG41080XQ Signal transduction protein with cbs domains EKQ63_05385 ENOG4105ETU transcriptional activator (TenA EKQ63_05395 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EKQ63_05405 ENOG4108VEU Thiamine monophosphate synthase EKQ63_05410 ENOG41080HI glycine oxidase EKQ63_05425 ENOG4105D06 uba thif-type nad fad binding protein EKQ63_05430 ENOG4105DWF phosphomethylpyrimidine kinase EKQ63_05480 ENOG4108INS Transcriptional regulator EKQ63_05495 ENOG4105C7N Xanthine uracil vitamin C permease EKQ63_05505 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EKQ63_05520 ENOG4105K63 Thioredoxin EKQ63_05540 ENOG4108B31 Spore germination protein EKQ63_05560 ENOG4107Y03 Nitroreductase EKQ63_05565 ENOG4105ED1 spovr family EKQ63_05575 ENOG4107QMW pyridine nucleotide-disulfide oxidoreductase EKQ63_05580 ENOG4105XTG Pfam:DUF156 EKQ63_05585 ENOG4105VFE sira family EKQ63_05590 ENOG4107TPS domain protein EKQ63_05595 ENOG4105VFE sira family EKQ63_05600 ENOG4105VFE sira family EKQ63_05610 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase EKQ63_05615 ENOG41087NI Sulfite exporter TauE/SafE EKQ63_05625 ENOG4108KGH TRANSCRIPTIONal EKQ63_05660 ENOG4105EMD TRANSCRIPTIONal EKQ63_05665 ENOG4105VCP PTS System EKQ63_05670 ENOG4105VZJ PTS System EKQ63_05690 ENOG41069ER domain protein EKQ63_05695 ENOG4107RBB ABC transporter, permease EKQ63_05700 ENOG4105C19 ABC transporter EKQ63_05730 ENOG4105WEF catalase EKQ63_05765 ENOG4107T5V SNARE associated Golgi EKQ63_05795 ENOG4105CUB amino acid EKQ63_05800 ENOG4107RWR Sodium hydrogen exchanger EKQ63_05810 ENOG4106KNT transcriptional regulator EKQ63_05850 ENOG4108YXU transcriptional regulator AsnC family EKQ63_05860 ENOG4105UBK short-chain dehydrogenase reductase EKQ63_05870 ENOG4105KPY Small multidrug resistance protein EKQ63_05875 ENOG4105KPY Small multidrug resistance protein EKQ63_05905 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) EKQ63_05910 ENOG4105E5W Transporter EKQ63_05920 ENOG4107RKG DJ-1/PfpI family EKQ63_05930 ENOG4105D5Q Arginine ornithine antiporter EKQ63_05935 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) EKQ63_05945 ENOG4105C26 Dehydrogenase EKQ63_05960 ENOG4105BZ1 (ABC) transporter EKQ63_05965 ENOG4105BZ1 (ABC) transporter EKQ63_05980 ENOG4105DRP amino acid AbC transporter EKQ63_05985 ENOG4105CDA abc transporter atp-binding protein EKQ63_06000 ENOG410839P EKQ63_06035 ENOG4107FQX Alpha-acetolactate decarboxylase EKQ63_06055 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EKQ63_06060 ENOG4105D4P Coproporphyrinogen iii oxidase EKQ63_06080 ENOG4105CHH sulfate transporter EKQ63_06115 ENOG4106AKK s-layer domain-containing protein EKQ63_06125 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein EKQ63_06130 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein EKQ63_06145 ENOG4105CGU Enoyl-CoA hydratase EKQ63_06165 ENOG4105DER m42 family EKQ63_06185 ENOG4105CTU Proline racemase EKQ63_06215 ENOG4105BZU Histidine kinase EKQ63_06225 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) EKQ63_06230 ENOG410609C Acyl carrier protein EKQ63_06260 ENOG4105C85 amino acid EKQ63_06275 ENOG4105C2C drug resistance transporter, Bcr CflA EKQ63_06280 ENOG4105CSH Transporter EKQ63_06290 ENOG4108MRH transcriptional regulatory protein EKQ63_06300 ENOG4105CH6 catalase EKQ63_06320 ENOG4107SCJ type I restriction enzyme EcoKI subunit R EKQ63_06365 ENOG4105CDU Replicative dna helicase EKQ63_06380 ENOG4105CDU Replicative dna helicase EKQ63_06405 ENOG41087YS Phage shock protein A EKQ63_06415 ENOG4105C0R drug resistance transporter emrb qaca subfamily EKQ63_06460 ENOG4105F27 Major Facilitator EKQ63_06465 ENOG4105WAB arsR family transcriptional regulator EKQ63_06490 ENOG4105CID antiterminator EKQ63_06495 ENOG4105C5Y PTS System EKQ63_06500 ENOG4105CS2 ec 3.2.1.21 EKQ63_06510 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EKQ63_06535 ENOG4105CMT Dihydroxyacetone kinase EKQ63_06550 ENOG4105CMT Dihydroxyacetone kinase EKQ63_06580 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase EKQ63_06665 ENOG4105WN5 stage II sporulation protein EKQ63_06675 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EKQ63_06685 ENOG4108MJI response regulator EKQ63_06690 ENOG4105BZU Histidine kinase EKQ63_06695 ENOG4105BZU Histidine kinase EKQ63_06715 ENOG4105K8R UPF0145 protein EKQ63_06755 ENOG4107VRP DNA repair exonuclease EKQ63_06760 ENOG4106D4I domain protein EKQ63_06765 ENOG4105D7V transposase EKQ63_06830 ENOG4108MUZ hydrolase EKQ63_06845 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator EKQ63_06860 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EKQ63_06870 ENOG4105EMN RNA polymerase sigma factor EKQ63_06880 ENOG4105CNI cell division protein FtsW EKQ63_06890 ENOG4105EEM helicase EKQ63_06900 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EKQ63_06925 ENOG4105K59 histidine triad (HIT) protein EKQ63_06985 ENOG410905X membrane-flanked domain protein EKQ63_06990 ENOG4105CKV Membrane EKQ63_07015 ENOG410905X membrane-flanked domain protein EKQ63_07020 ENOG4105CKV Membrane EKQ63_07025 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation EKQ63_07030 ENOG4105BZ4 penicillin-binding protein EKQ63_07040 ENOG4107QME Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) EKQ63_07045 ENOG4105C1Q protoporphyrinogen oxidase EKQ63_07075 ENOG4105NA0 Transcriptional regulator EKQ63_07090 ENOG4105ECB domain protein EKQ63_07110 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) EKQ63_07120 ENOG4105D29 Helix-turn-helix type 11 domain protein EKQ63_07130 ENOG4106AXD EKQ63_07135 ENOG4108RQ5 Beta-lactamase domain-containing protein EKQ63_07140 ENOG4105DF9 Lipoate-protein, ligase EKQ63_07150 ENOG4105CEY Amp-dependent synthetase and ligase EKQ63_07165 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EKQ63_07170 ENOG4108I5D sulfate abc transporter EKQ63_07175 ENOG4105ECW sulfate abc transporter EKQ63_07185 ENOG4106XHW Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity (By similarity) EKQ63_07195 ENOG4105ENX hydrolase EKQ63_07200 ENOG4107RN3 metallophosphoesterase EKQ63_07205 ENOG4107TVP HD domain protein EKQ63_07215 ENOG4105C57 major facilitator superfamily EKQ63_07225 ENOG4108AEY RNA polymerase sigma factor EKQ63_07230 ENOG41086D8 Transcriptional regulator EKQ63_07245 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EKQ63_07270 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 EKQ63_07290 ENOG4105ZU5 s-layer protein EKQ63_07295 ENOG4107QP3 malate synthase g EKQ63_07310 ENOG4105VEQ Cold shock protein EKQ63_07325 ENOG4105XVF Competence transcription factor EKQ63_07400 ENOG4105ERH Fumarylacetoacetate hydrolase EKQ63_07425 ENOG4105CAQ asparagine synthetase EKQ63_07430 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) EKQ63_07435 ENOG4105CH6 catalase EKQ63_07480 ENOG4105BZU Histidine kinase EKQ63_07500 ENOG4108VPT UPF0234 protein EKQ63_07505 ENOG4105QNR S1 RNA binding domain protein EKQ63_07510 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EKQ63_07520 ENOG4107AYK membrAne EKQ63_07525 ENOG41073B9 EKQ63_07535 ENOG4108KP7 hydrolase EKQ63_07545 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EKQ63_07570 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) EKQ63_07575 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EKQ63_07590 ENOG4105C31 Tryptophanyl-tRNA synthetase EKQ63_07610 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EKQ63_07615 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EKQ63_07625 ENOG4108JQ7 (ABC) transporter EKQ63_07630 ENOG4105UQX Mate efflux family protein EKQ63_07650 ENOG4108ZCF integral membrane protein EKQ63_07660 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EKQ63_07670 ENOG4105DPN Oligoendopeptidase f EKQ63_07680 ENOG4108Z18 K06886 hemoglobin EKQ63_07685 ENOG4105MIX Adenylate cyclase EKQ63_07690 ENOG4106EFP UPF0738 protein EKQ63_07705 ENOG4105EMS pseudouridine synthase EKQ63_07725 ENOG4105K64 Glycosyl transferase, family 2 EKQ63_07745 ENOG4107TVC Glycosyl transferase, family 2 EKQ63_07765 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) EKQ63_07770 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase EKQ63_07780 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase EKQ63_07865 ENOG4105CK7 Sodium proline symporter EKQ63_07875 ENOG4105CRQ synthase (Component I) EKQ63_07880 ENOG4105DDQ anthranilate synthase EKQ63_07980 ENOG4105C7S Dehydrogenase EKQ63_07990 ENOG4105VZ8 Transcriptional regulator EKQ63_08070 ENOG4105DZ1 carboxypeptidase EKQ63_08075 ENOG4105VFR signal peptidase EKQ63_08110 ENOG4105C26 Dehydrogenase EKQ63_08120 ENOG4105F38 ABC transporter, permease EKQ63_08125 ENOG4105D38 putrescine abc transporter EKQ63_08130 ENOG4107RUE extracellular solute-binding protein family 1 EKQ63_08140 ENOG4105EYF MMPL domain protein EKQ63_08150 ENOG4108YBP pseudouridine synthase EKQ63_08160 ENOG4105K4I Scp-like extracellular EKQ63_08165 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) EKQ63_08170 ENOG4105CQB FAD linked oxidase domain protein EKQ63_08185 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_08190 ENOG4105BZU Histidine kinase EKQ63_08195 ENOG4105JXH GntR family transcriptional regulator EKQ63_08215 ENOG4106A3R peptidase EKQ63_08225 ENOG4108QTI )-transporter EKQ63_08235 ENOG4107TS3 membrane protein, TerC EKQ63_08240 ENOG4105CZN Potassium uptake protein EKQ63_08245 ENOG410681C small acid-soluble spore protein EKQ63_08250 ENOG4108Z7G MaoC domain protein dehydratase EKQ63_08270 ENOG4105CHR reductase EKQ63_08300 ENOG4105C4Y ABC transporter EKQ63_08305 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EKQ63_08310 ENOG4107RCV ABC transporter, permease EKQ63_08330 ENOG4105E98 transcriptional regulator DeoR family EKQ63_08340 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) EKQ63_08350 ENOG4105PXI polysaccharide deacetylase EKQ63_08360 ENOG4105BZU Histidine kinase EKQ63_08365 ENOG41090MY MarR family Transcriptional regulator EKQ63_08375 ENOG4106DF1 EKQ63_08380 ENOG4105BZU Histidine kinase EKQ63_08390 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase EKQ63_08395 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EKQ63_08435 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) EKQ63_08450 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EKQ63_08455 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family EKQ63_08460 ENOG4105CZV ABC transporter EKQ63_08470 ENOG4105CJ1 ABC, transporter EKQ63_08475 ENOG4108TU7 Inherit from COG: (ABC) transporter EKQ63_08510 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A EKQ63_08515 ENOG4105EA8 2-Nitropropane dioxygenase EKQ63_08520 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD EKQ63_08530 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein EKQ63_08550 ENOG4105NQC Flavodoxin EKQ63_08570 ENOG4107QMU Mate efflux family protein EKQ63_08610 ENOG4105CZN Potassium uptake protein EKQ63_08615 ENOG41063Y9 EKQ63_08620 ENOG4105KBJ sporulation protein ytfj EKQ63_08645 ENOG4105CM2 brancheD-chain amino acid aminotransferase EKQ63_08650 ENOG4105C7K acetolactate synthase EKQ63_08655 ENOG4108ZP8 Acetolactate synthase small subunit EKQ63_08730 ENOG4107RVV histidinol phosphate phosphatase, hisj family EKQ63_08745 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase EKQ63_08750 ENOG4105E0M Sulfatase EKQ63_08760 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EKQ63_08780 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) EKQ63_08785 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) EKQ63_08795 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) EKQ63_08800 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein EKQ63_08805 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein EKQ63_08810 ENOG4105C8J )-transporter EKQ63_08830 ENOG4105DFD Na H antiporter EKQ63_08850 ENOG4105ENE Histidine kinase EKQ63_08855 ENOG4105WH1 Two component transcriptional regulator luxr family EKQ63_08875 ENOG41089UC methyltransferase, type 11 EKQ63_08920 ENOG4105CJ3 phosphate transporter EKQ63_08925 ENOG4107GRR phosphate transport regulator EKQ63_08930 ENOG4105BZ4 penicillin-binding protein EKQ63_08945 ENOG4105BZU Histidine kinase EKQ63_08950 ENOG4105I3N Conserved Protein EKQ63_08965 ENOG4105BZU Histidine kinase EKQ63_08995 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EKQ63_09000 ENOG4105DZ1 carboxypeptidase EKQ63_09005 ENOG4108JIC nucleoside recognition domain protein EKQ63_09015 ENOG4105FE9 pseudouridine synthase EKQ63_09025 ENOG4107TWT Cytochrome c biogenesis protein EKQ63_09030 ENOG4105CRE cytochrome C EKQ63_09035 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_09040 ENOG4105BZU Histidine kinase EKQ63_09045 ENOG4108WBT adenosyltransferase EKQ63_09050 ENOG41063SB peptidase EKQ63_09060 ENOG4108SAX Membrane EKQ63_09075 ENOG4105C9U ATP-dependent DNA helicase RecQ EKQ63_09080 ENOG4105I7S Abortive infection protein EKQ63_09090 ENOG4107RGJ metallophosphoesterase EKQ63_09095 ENOG4107X2D transcriptional regulator, merr family EKQ63_09100 ENOG4108S6Z Negative regulator of genetic competence EKQ63_09125 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase EKQ63_09130 ENOG4105HDK L-asparaginase EKQ63_09160 ENOG4105S2F EKQ63_09165 ENOG41065D1 EKQ63_09195 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) EKQ63_09210 ENOG4105XXQ heptaprenyl diphosphate synthase component I EKQ63_09220 ENOG4105EAH synthase EKQ63_09250 ENOG41068YB TPR repeat-containing protein EKQ63_09265 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) EKQ63_09270 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) EKQ63_09305 ENOG4108JYZ YitT family EKQ63_09310 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase EKQ63_09325 ENOG4105FJR Lmbe family EKQ63_09330 ENOG4105CPK Glycosyl transferase (Group 1 EKQ63_09365 ENOG4105DVT helicase EKQ63_09370 ENOG4105YAC EKQ63_09390 ENOG4105CSM endonuclease III EKQ63_09400 ENOG4105BZ4 penicillin-binding protein EKQ63_09455 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) EKQ63_09465 ENOG4105DVT helicase EKQ63_09470 ENOG4105CTD carboxy-peptidase EKQ63_09480 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EKQ63_09495 ENOG4105DHF Membrane EKQ63_09500 ENOG410890F Dynamin family EKQ63_09510 ENOG4108W0I acetyltransferase EKQ63_09520 ENOG4105KHC sulfurtransferase EKQ63_09585 ENOG4105CPK Glycosyl transferase (Group 1 EKQ63_09600 ENOG4108SZE gCN5-related N-acetyltransferase EKQ63_09620 ENOG41081VK Ribonuclease EKQ63_09685 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EKQ63_09690 ENOG4107RWR Sodium hydrogen exchanger EKQ63_09695 ENOG4105CN5 Metallo-Beta-Lactamase EKQ63_09700 ENOG4108Z5V transcriptional regulator, merr family EKQ63_09710 ENOG4105H67 Protein of unknown function (DUF421) EKQ63_09715 ENOG41080C8 DUF218 domain EKQ63_09770 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) EKQ63_09780 ENOG4107R0U MotA TolQ exbB proton channel EKQ63_09785 ENOG4105ER2 Ompa motb domain protein EKQ63_09790 ENOG4107YTP response regulator receiver protein EKQ63_09795 ENOG4105CBS Chea signal transduction histidine kinase EKQ63_09800 ENOG4105DD5 Flagellar motor switch protein EKQ63_09815 ENOG4105BZU Histidine kinase EKQ63_09835 ENOG4105E1Q flagellar hook-associated protein EKQ63_09840 ENOG4105DTJ flagellar hook-associated protein EKQ63_09845 ENOG4107TPX flagellar hook-associated EKQ63_09860 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) EKQ63_09865 ENOG4108ZC9 flagellar basal-body rod protein flgc EKQ63_09870 ENOG41075Z6 flagellar hook-basal body complex protein fliE EKQ63_09875 ENOG4107U2N Flagellar M-ring protein EKQ63_09880 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EKQ63_09910 ENOG4105BZE flagellar hook protein, FlgE EKQ63_09925 ENOG4107R88 Chemotaxis protein (CheV) EKQ63_09935 ENOG4105I03 Flagellin EKQ63_09940 ENOG4105I03 Flagellin EKQ63_09945 ENOG4105E4C Lytic transglycosylase catalytic EKQ63_09955 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EKQ63_09960 ENOG4105DD5 Flagellar motor switch protein EKQ63_09970 ENOG4105CN7 Flagellar biosynthetic protein FliP EKQ63_09975 ENOG4105VS8 Flagellar biosynthetic protein fliq EKQ63_09985 ENOG4105D00 flagellar biosynthetic protein flhB EKQ63_09990 ENOG4105D7B Flagellar biosynthesis protein flha EKQ63_09995 ENOG4105FZW flagellar biosynthesis regulator FlhF EKQ63_10000 ENOG4105KTQ flagellar basal-body rod protein EKQ63_10035 ENOG4105KAC Antibiotic biosynthesis monooxygenase EKQ63_10060 ENOG4105DUM transcriptional regulator, lysR family EKQ63_10065 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EKQ63_10075 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component EKQ63_10080 ENOG4105CN5 Metallo-Beta-Lactamase EKQ63_10095 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr EKQ63_10120 ENOG4105CVJ phosphoglycerate mutase EKQ63_10130 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) EKQ63_10140 ENOG4105K56 Transcriptional regulator EKQ63_10150 ENOG4105CAQ asparagine synthetase EKQ63_10170 ENOG4105PGM cation diffusion facilitator family transporter EKQ63_10180 ENOG4105DRR Transcriptional regulator, GntR family EKQ63_10185 ENOG4108UZ3 Transporter EKQ63_10190 ENOG4105CKI cobalamin synthesis protein EKQ63_10195 ENOG4108PJD permease EKQ63_10210 ENOG4105DFD Na H antiporter EKQ63_10215 ENOG4105C9Q fumarate hydratase class II EKQ63_10225 ENOG4105C5X domain protein EKQ63_10235 ENOG4107QJQ Mate efflux family protein EKQ63_10240 ENOG4105EC3 peptidase S51, dipeptidase E EKQ63_10280 ENOG4106BRA Membrane EKQ63_10320 ENOG4105CJ1 ABC, transporter EKQ63_10345 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) EKQ63_10355 ENOG4108IJ0 Aspartate ammonia-lyase EKQ63_10360 ENOG4105C6K Malic enzyme EKQ63_10375 ENOG4105C0D helicase EKQ63_10395 ENOG4108IMY Transcriptional regulator EKQ63_10425 ENOG4105FVX EKQ63_10470 ENOG4105CSR polyphosphate kinase 2 EKQ63_10475 ENOG4105U3E Transcriptional regulator EKQ63_10485 ENOG4105DXI Major Facilitator superfamily EKQ63_10510 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EKQ63_10520 ENOG4105EU0 Major facilitator Superfamily EKQ63_10525 ENOG4105C6T cysteine synthase EKQ63_10545 ENOG4105C8J )-transporter EKQ63_10555 ENOG4105X5K response regulator receiver protein EKQ63_10560 ENOG4105H67 Protein of unknown function (DUF421) EKQ63_10575 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) EKQ63_10580 ENOG4105CM2 brancheD-chain amino acid aminotransferase EKQ63_10585 ENOG4105C7K acetolactate synthase EKQ63_10595 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase EKQ63_10605 ENOG4105C7B Threonine dehydratase EKQ63_10625 ENOG4105C6X Major Facilitator EKQ63_10630 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EKQ63_10650 ENOG4105DY9 regulatoR EKQ63_10655 ENOG4105CYC Transferase EKQ63_10675 ENOG4105F6J Alpha beta hydrolase fold EKQ63_10705 ENOG41068WN EKQ63_10725 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) EKQ63_10740 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) EKQ63_10745 ENOG4105C0X amino acid EKQ63_10780 ENOG4107RHR regulatoR EKQ63_10790 ENOG4105D9N nucleoside EKQ63_10795 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) EKQ63_10820 ENOG4107RAQ aminopeptidase EKQ63_10865 ENOG4108T5E Copper resistance protein EKQ63_10870 ENOG4105KTB nuclear export factor GLE1 EKQ63_10875 ENOG4107RT3 EamA-like transporter family EKQ63_10880 ENOG4105GZI Transcriptional regulator EKQ63_10885 ENOG4108Z40 Transcriptional regulator EKQ63_10890 ENOG4107ZXU DSBA oxidoreductase EKQ63_10895 ENOG4108TVJ Nitroreductase EKQ63_10905 ENOG4106F5Q Membrane EKQ63_10910 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) EKQ63_10925 ENOG4105CKI cobalamin synthesis protein EKQ63_10945 ENOG4108Z7G MaoC domain protein dehydratase EKQ63_10950 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) EKQ63_10965 ENOG4105C0Z ABC transporter EKQ63_10970 ENOG4108IV0 ABC, transporter EKQ63_10975 ENOG4105C32 Amino acid ABC transporter (Permease) EKQ63_10985 ENOG4105SKE transcriptional Regulator LysR family EKQ63_10995 ENOG4105MDS 4-oxalocrotonate tautomerase EKQ63_11015 ENOG4105C4M (Ubiquinol oxidase) subunit I EKQ63_11020 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EKQ63_11025 ENOG4108JJ9 ABC, transporter EKQ63_11030 ENOG4108JJ8 (ABC) transporter EKQ63_11040 ENOG4105K64 Glycosyl transferase, family 2 EKQ63_11050 ENOG4108UT6 Transferase hexapeptide repeat containing protein EKQ63_11105 ENOG4105BZ1 (ABC) transporter EKQ63_11110 ENOG4105EFI regulatoR EKQ63_11115 ENOG4105BZU Histidine kinase EKQ63_11130 ENOG4108VQJ O-methyltransferase EKQ63_11135 ENOG41075D4 Aminoglycoside 6-adenylyltransferase EKQ63_11140 ENOG4108ZJ4 polysaccharide deacetylase EKQ63_11160 ENOG4105D6E homoserine dehydrogenase EKQ63_11185 ENOG4108KGH TRANSCRIPTIONal EKQ63_11200 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EKQ63_11205 ENOG4105BZU Histidine kinase EKQ63_11210 ENOG4107VMI polysaccharide deacetylase EKQ63_11220 ENOG4105KT7 mgtC SapB transporter EKQ63_11225 ENOG4105VRR gCN5-related N-acetyltransferase EKQ63_11230 ENOG4105YWU small acid-soluble spore protein EKQ63_11240 ENOG4108ZUB Lysine exporter protein (Lyse ygga) EKQ63_11245 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EKQ63_11295 ENOG4105KRN Transcriptional regulator, abrb family EKQ63_11305 ENOG4105YVS arsR family transcriptional regulator EKQ63_11310 ENOG4105CPC Aldo Keto reductase EKQ63_11315 ENOG4107XZQ multidrug resistance protein EKQ63_11360 ENOG4108K88 Membrane EKQ63_11365 ENOG4108WPJ Ferritin-like domain EKQ63_11380 ENOG4105DEN Luciferase family EKQ63_11395 ENOG4105VMI -acetyltransferase EKQ63_11400 ENOG4107QM2 Aldo Keto reductase EKQ63_11405 ENOG4105CKI cobalamin synthesis protein EKQ63_11415 ENOG4105DSE periplasmic solute binding protein EKQ63_11420 ENOG4105K4T epimerase EKQ63_11430 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EKQ63_11455 ENOG4107TB6 phosphoglycerate mutase EKQ63_11475 ENOG4107T5V SNARE associated Golgi EKQ63_11490 ENOG4108PJD permease EKQ63_11500 ENOG4108S4H thioesterase Superfamily protein EKQ63_11510 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) EKQ63_11530 ENOG4105SXS Protein of unknown function (DUF456) EKQ63_11535 ENOG4105C37 (CBS) domain EKQ63_11555 ENOG4108Z7R Chaperone CsaA EKQ63_11575 ENOG4108ZRV stage ii sporulation protein p EKQ63_11585 ENOG4108VXD carboxy-peptidase EKQ63_11625 ENOG4108X4Q Hydrolase EKQ63_11635 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EKQ63_11640 ENOG4107RBS Methyltransferase EKQ63_11655 ENOG41087PP glycosyltransferase MGT family EKQ63_11660 ENOG4108JYZ YitT family EKQ63_11665 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EKQ63_11695 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) EKQ63_11720 ENOG4105KBJ sporulation protein ytfj EKQ63_11745 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) EKQ63_11765 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EKQ63_11775 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EKQ63_11780 ENOG4105EMN RNA polymerase sigma factor EKQ63_11815 ENOG4108V06 Glutathione peroxidase EKQ63_11830 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EKQ63_11875 ENOG4105MCT stage V sporulation protein S EKQ63_11900 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) EKQ63_11920 ENOG4108IBT Inherit from COG: transposase EKQ63_11935 ENOG4105C5H ABC transporter EKQ63_11950 ENOG4108UUM single-stranded DNA-binding protein EKQ63_11955 ENOG4105EGD dinuclear metal center protein, YbgI family EKQ63_11975 ENOG4107YX5 Pfam:DUF548 EKQ63_11980 ENOG4105C75 arginyL-tRNA synthetase EKQ63_12025 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) EKQ63_12035 ENOG4105C5S asparaginyl-tRNA synthetase EKQ63_12055 ENOG4105EC2 ftsk spoIIIe EKQ63_12135 ENOG4105C8J )-transporter EKQ63_12155 ENOG4107XGZ Hydrolase EKQ63_12160 ENOG4105CY2 Citrate transporter EKQ63_12165 ENOG4105C0A alcohol dehydrogenase EKQ63_12180 ENOG4105KD7 acetyltransferase EKQ63_12185 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase EKQ63_12210 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 EKQ63_12230 ENOG4107UQD Hydrolyzes N-terminal residues in D-amino acid- containing peptides (By similarity) EKQ63_12250 ENOG4107RVG penicillin-binding protein EKQ63_12260 ENOG4105E9Q Acyl-transferase EKQ63_12265 ENOG4108UT2 hemolysin iii EKQ63_12275 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) EKQ63_12285 ENOG4108RCR degv family EKQ63_12290 ENOG4105E8R UPF0173 metal-dependent hydrolase EKQ63_12295 ENOG4108KF3 Electron transport protein SCO1 SenC EKQ63_12300 ENOG4107Y70 Heat shock protein EKQ63_12305 ENOG4105CAQ asparagine synthetase EKQ63_12320 ENOG4108MES Periplasmic binding protein EKQ63_12325 ENOG4105F0I Aminotransferase EKQ63_12360 ENOG4105D8X mechanosensitive ion channel EKQ63_12365 ENOG4105BZU Histidine kinase EKQ63_12370 ENOG4105WH1 Two component transcriptional regulator luxr family EKQ63_12375 ENOG4105FQP Beta-lactamase EKQ63_12380 ENOG4106KNT transcriptional regulator EKQ63_12420 ENOG4105CMG Carbohydrate kinase EKQ63_12425 ENOG4105C6Z Gluconate EKQ63_12460 ENOG4108IJ8 ABC transporter EKQ63_12465 ENOG4105E90 ABC transporter EKQ63_12500 ENOG4105C37 (CBS) domain EKQ63_12525 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EKQ63_12540 ENOG4107S4Y M20 DapE family protein YgeY EKQ63_12545 ENOG4108TSC N-acetyltransferase EKQ63_12550 ENOG4108JUB Transcriptional regulator EKQ63_12555 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EKQ63_12600 ENOG410841Q phosphoesterase PA-phosphatase related protein EKQ63_12610 ENOG4105SZ6 Thioredoxin EKQ63_12675 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) EKQ63_12725 ENOG4105BZ4 penicillin-binding protein EKQ63_12735 ENOG4105CZM Major Facilitator EKQ63_12740 ENOG4105W8X HesB YadR YfhF-family protein EKQ63_12750 ENOG4105DXD 2-methylcitrate dehydratase EKQ63_12755 ENOG4105CR4 methylisocitrate lyase EKQ63_12760 ENOG4105C1G acyl-Coa dehydrogenase EKQ63_12765 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EKQ63_12780 ENOG4105E39 Enoyl-CoA hydratase EKQ63_12795 ENOG4107RFY SbcCD D subunit EKQ63_12820 ENOG4105FCD Major Facilitator EKQ63_12830 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase EKQ63_12835 ENOG4105E4F Isochorismate synthase EKQ63_12840 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase EKQ63_12845 ENOG4105WQI isochorismatase EKQ63_12850 ENOG4105CEY Amp-dependent synthetase and ligase EKQ63_12855 ENOG4105WQT MbtH domain protein EKQ63_12860 ENOG4105C0R drug resistance transporter emrb qaca subfamily EKQ63_12875 ENOG4105K70 DNA-binding protein EKQ63_12895 ENOG4105BZG amino acid carrier protein EKQ63_12920 ENOG4105FE9 pseudouridine synthase EKQ63_12925 ENOG4105C22 threonyL-tRNA synthetase EKQ63_12930 ENOG4105C19 ABC transporter EKQ63_12940 ENOG4107SKW Inherit from COG: Alpha beta hydrolase EKQ63_13010 ENOG4107MII Sugar-specific transcriptional regulator TrmB EKQ63_13025 ENOG4105EYF MMPL domain protein EKQ63_13050 ENOG4105WCN acetyltransferase EKQ63_13075 ENOG4105C1Q protoporphyrinogen oxidase EKQ63_13085 ENOG41068WN EKQ63_13095 ENOG4105VEQ Cold shock protein EKQ63_13115 ENOG410667J hydrolase EKQ63_13125 ENOG4107V2S Transcriptional regulator EKQ63_13130 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EKQ63_13145 ENOG4105DND Transcriptional regulator EKQ63_13150 ENOG4108RPX mosc domain containing protein EKQ63_13165 ENOG4105BZ1 (ABC) transporter EKQ63_13170 ENOG4105BZ1 (ABC) transporter EKQ63_13195 ENOG4108JCI Transcriptional regulator EKQ63_13225 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EKQ63_13240 ENOG4108KPJ rna polymerase sigma factor EKQ63_13260 ENOG4105F32 YngK protein EKQ63_13285 ENOG4105RD7 BadF BadG BcrA BcrD EKQ63_13295 ENOG4107STF Involved in phosphonate degradation (By similarity) EKQ63_13305 ENOG4108INS Transcriptional regulator EKQ63_13330 ENOG4108JMX Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) EKQ63_13340 ENOG4105C1J atp-dependent rna helicase EKQ63_13355 ENOG4108RZE Tetr family transcriptional regulator EKQ63_13370 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EKQ63_13375 ENOG41088CC tellurite resistance protein tehB EKQ63_13385 ENOG4108I0C methyltransferase EKQ63_13390 ENOG4107RA9 decarboxylase EKQ63_13395 ENOG4105K56 Transcriptional regulator EKQ63_13400 ENOG4105DKJ Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EKQ63_13425 ENOG4105CIN aminoacyl-histidine dipeptidase EKQ63_13435 ENOG4105EQK -acetyltransferase EKQ63_13460 ENOG4107RVG penicillin-binding protein EKQ63_13475 ENOG4107RF6 penicillin-binding protein EKQ63_13480 ENOG4107RF6 penicillin-binding protein EKQ63_13495 ENOG4105EXC Acyl-transferase EKQ63_13540 ENOG4105CEP NADH dehydrogenase EKQ63_13560 ENOG4105CJ1 ABC, transporter EKQ63_13570 ENOG4107Z3H Transcriptional regulator, TetR family EKQ63_13585 ENOG4105C1G acyl-Coa dehydrogenase EKQ63_13590 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EKQ63_13595 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit EKQ63_13600 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase EKQ63_13605 ENOG4105E39 Enoyl-CoA hydratase EKQ63_13610 ENOG4107QX3 carboxylase EKQ63_13615 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EKQ63_13635 ENOG4105DBI uridine monophosphokinase EKQ63_13680 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EKQ63_13745 ENOG41089UC methyltransferase, type 11 EKQ63_13760 ENOG4105CJ1 ABC, transporter EKQ63_13775 ENOG4108DMH HTH_ARAC EKQ63_13795 ENOG4105EFA 4-hydroxyphenylacetate EKQ63_13815 ENOG410900G Protein of unknown function (DUF421) EKQ63_13830 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein EKQ63_13840 ENOG4105DK7 lysyl-tRNA synthetase EKQ63_13910 ENOG4105D6E homoserine dehydrogenase EKQ63_13925 ENOG4105ETU transcriptional activator (TenA EKQ63_14015 ENOG410667J hydrolase EKQ63_14020 ENOG4105BZU Histidine kinase EKQ63_14025 ENOG4107RF6 penicillin-binding protein EKQ63_14060 ENOG4108HGU Histidine kinase EKQ63_14070 ENOG4105RHY Pfam:UPF0157 EKQ63_14080 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_14085 ENOG4105GR3 Histidine kinase EKQ63_14090 ENOG4105CB2 alcohol dehydrogenase EKQ63_14095 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EKQ63_14100 ENOG4105CJN penicillin-binding protein EKQ63_14105 ENOG4108IG5 Transcriptional regulator EKQ63_14110 ENOG4105CHR reductase EKQ63_14160 ENOG4108V4B ThiJ pfpI EKQ63_14175 ENOG4107Y80 Major Facilitator superfamily EKQ63_14190 ENOG4107VXM glycerophosphoryl diester phosphodiesterase EKQ63_14210 ENOG4107Y9U Membrane EKQ63_14230 ENOG4105EGD dinuclear metal center protein, YbgI family EKQ63_14250 ENOG4105FCD Major Facilitator EKQ63_14255 ENOG4105E09 nadh pyrophosphatase EKQ63_14260 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EKQ63_14295 ENOG4105KME endoribonuclease L-psp EKQ63_14300 ENOG4108XI2 Domain of unknown function (DUF1963) EKQ63_14325 ENOG4108NRW Phospholipase, patatin family EKQ63_14330 ENOG4105KWG Pfam:DUF1696 EKQ63_14340 ENOG4108YYS metal-dependent hydrolase (By similarity) EKQ63_14365 ENOG4105PKS Excinuclease abc c subunit domain protein EKQ63_14405 ENOG4107VFR oxidoreductase EKQ63_14425 ENOG4105PAD Hydrolase EKQ63_14430 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_14435 ENOG4105BZU Histidine kinase EKQ63_14470 ENOG4107WD8 ABC transporter, permease EKQ63_14480 ENOG4108IUM Glycogen debranching enzyme EKQ63_14495 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EKQ63_14505 ENOG4107RQD Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity) EKQ63_14510 ENOG4105FDR Membrane EKQ63_14515 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EKQ63_14520 ENOG4105CIS alcohol dehydrogenase EKQ63_14570 ENOG4105MSI germination protein ypeb EKQ63_14610 ENOG4107Z3H Transcriptional regulator, TetR family EKQ63_14615 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) EKQ63_14650 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family EKQ63_14665 ENOG4105E98 transcriptional regulator DeoR family EKQ63_14685 ENOG4107QKR Dehydrogenase EKQ63_14695 ENOG4107RUY (E1 component), alpha subunit EKQ63_14705 ENOG4105E1F short-chain dehydrogenase reductase EKQ63_14710 ENOG4105RHY Pfam:UPF0157 EKQ63_14715 ENOG4105DBI uridine monophosphokinase EKQ63_14755 ENOG4107SQ8 Glycine betaine EKQ63_14760 ENOG4108IJ7 Glycine betaine EKQ63_14790 ENOG41082BV acetyltransferase EKQ63_14795 ENOG4108M1A Chitin-binding protein EKQ63_14800 ENOG41087PP glycosyltransferase MGT family EKQ63_14825 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EKQ63_14830 ENOG4105MSB protein, conserved in bacteria EKQ63_14840 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EKQ63_14865 ENOG4108Z7F N-acetyltransferase EKQ63_14885 ENOG4105EEM helicase EKQ63_14900 ENOG4105C9U ATP-dependent DNA helicase RecQ EKQ63_14950 ENOG4108M1A Chitin-binding protein EKQ63_14975 ENOG4105BZG amino acid carrier protein EKQ63_14980 ENOG4105C26 Dehydrogenase EKQ63_14985 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EKQ63_14990 ENOG4105CTU Proline racemase EKQ63_14995 ENOG4105CTU Proline racemase EKQ63_15000 ENOG41080HI glycine oxidase EKQ63_15010 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein EKQ63_15050 ENOG4105DCI Phosphohydrolase EKQ63_15055 ENOG4107T5V SNARE associated Golgi EKQ63_15070 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD EKQ63_15100 ENOG4105DTQ mandelate racemase muconate lactonizing EKQ63_15150 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) EKQ63_15155 ENOG4105BZU Histidine kinase EKQ63_15160 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_15180 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 EKQ63_15185 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) EKQ63_15200 ENOG4105DPN Oligoendopeptidase f EKQ63_15205 ENOG4105DVH amino acid EKQ63_15225 ENOG4105EPR degv family EKQ63_15300 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) EKQ63_15305 ENOG4106K7D Major facilitator family transporter EKQ63_15325 ENOG4107BMA Transglycosylase associated protein EKQ63_15340 ENOG41089UC methyltransferase, type 11 EKQ63_15380 ENOG4105CHM Aminotransferase EKQ63_15395 ENOG4108ZMI UPF0477 protein EKQ63_15410 ENOG4105DVE abc transporter atp-binding protein EKQ63_15455 ENOG4105C02 permease EKQ63_15465 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) EKQ63_15470 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EKQ63_15475 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein EKQ63_15500 ENOG4105E09 nadh pyrophosphatase EKQ63_15520 ENOG4108AQF aminoglycoside N(3)-acetyltransferase EKQ63_15575 ENOG4107VMI polysaccharide deacetylase EKQ63_15585 ENOG4108ZCF integral membrane protein EKQ63_15595 ENOG4105C5H ABC transporter EKQ63_15605 ENOG4105EYF MMPL domain protein EKQ63_15610 ENOG41082JN Transcriptional regulator EKQ63_15635 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase EKQ63_15640 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase EKQ63_15655 ENOG4106XMA In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity) EKQ63_15680 ENOG41069ER domain protein EKQ63_15695 ENOG4105DNP FAD linked oxidase domain protein EKQ63_15705 ENOG4105MKU Transcriptional regulator EKQ63_15720 ENOG4105D4B ABC, transporter EKQ63_15730 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane EKQ63_15740 ENOG4105DKT Transcriptional regulator EKQ63_15745 ENOG4108EMV Catalyzes the phosphorylation of autoinducer 2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of 4,5-dihydroxy-2,3- pentanedione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position (By similarity) EKQ63_15755 ENOG41061GT Aldolase EKQ63_15785 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) EKQ63_15815 ENOG4105II7 pyrroline-5-carboxylate reductase EKQ63_15825 ENOG4107258 Transcriptional regulator EKQ63_15840 ENOG4105E0Y RtcB Protein EKQ63_15845 ENOG4105ECK Fatty Acid Desaturase EKQ63_15855 ENOG4105G6Z alkaline phosphatase EKQ63_15865 ENOG4105VMP Transcriptional regulator EKQ63_15880 ENOG41090T1 Membrane EKQ63_15890 ENOG4108WCX response regulator EKQ63_15905 ENOG41068WN EKQ63_15935 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EKQ63_15955 ENOG4105C8Y Acetylornithine aminotransferase EKQ63_16000 ENOG4105C7R Atpase associated with various cellular activities aaa_3 EKQ63_16005 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EKQ63_16010 ENOG4105CHH sulfate transporter EKQ63_16030 ENOG4108TVJ Nitroreductase EKQ63_16035 ENOG4105FS7 Transcriptional regulator EKQ63_16065 ENOG4108DMH HTH_ARAC EKQ63_16070 ENOG4108XET gCN5-related N-acetyltransferase EKQ63_16095 ENOG4107XJU UPF0178 protein EKQ63_16130 ENOG410635A Membrane EKQ63_16140 ENOG4108IQI permease EKQ63_16150 ENOG4105F1N DNA alkylation repair EKQ63_16165 ENOG4107ZY0 Phenazine biosynthesis-like protein EKQ63_16185 ENOG4105C3F Signal peptidase i EKQ63_16190 ENOG4107RF6 penicillin-binding protein EKQ63_16200 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EKQ63_16235 ENOG4105P4J Allophanate hydrolase, subunit 1 EKQ63_16240 ENOG4107258 Transcriptional regulator EKQ63_16255 ENOG4106N3A copper homeostasis protein cutc EKQ63_16260 ENOG4108ZRV stage ii sporulation protein p EKQ63_16265 ENOG4105FDT acyl-CoA dehydrogenase EKQ63_16280 ENOG4105DWD nucleoside recognition domain protein EKQ63_16325 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) EKQ63_16330 ENOG41087PP glycosyltransferase MGT family EKQ63_16355 ENOG4105E2A Dehydrogenase EKQ63_16365 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EKQ63_16385 ENOG4105CGH 5'-nucleotidase EKQ63_16395 ENOG4105CHJ isochorismatase hydrolase EKQ63_16455 ENOG41075H3 AraC family transcriptional regulator EKQ63_16470 ENOG4105YWU small acid-soluble spore protein EKQ63_16475 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) EKQ63_16480 ENOG4105CUB amino acid EKQ63_16485 ENOG4105II7 pyrroline-5-carboxylate reductase EKQ63_16490 ENOG4108NHD germination protein EKQ63_16495 ENOG4108Q8B Spore germination protein EKQ63_16530 ENOG4105CGH 5'-nucleotidase EKQ63_16555 ENOG4105DH8 myo-inositol catabolism EKQ63_16560 ENOG4105D2N Aldolase EKQ63_16585 ENOG4105CK5 oxidoreductase EKQ63_16595 ENOG4105IE8 Alpha-ketoglutarate permease EKQ63_16600 ENOG4105ETE Transcriptional regulator (LacI family EKQ63_16620 ENOG4108606 TspO/MBR family EKQ63_16625 ENOG4105CVP deoxyribo-dipyrimidine photolyase EKQ63_16660 ENOG4108TWJ NADH dehydrogenase subunit 5 EKQ63_16665 ENOG4105GPN Uncharacterized conserved protein (DUF2294) EKQ63_16680 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase EKQ63_16735 ENOG41074FZ May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity) EKQ63_16765 ENOG4105D6J arsenicaL-resistance protein EKQ63_16770 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase EKQ63_16775 ENOG41085FC arsR family transcriptional regulator EKQ63_16785 ENOG4105NAE bifunctional deaminase-reductase domain protein EKQ63_16805 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EKQ63_16845 ENOG4107P5I polyketide synthase EKQ63_16850 ENOG4108IG5 Transcriptional regulator EKQ63_16855 ENOG4105F27 Major Facilitator EKQ63_16860 ENOG4105M4P Tetr family transcriptional regulator EKQ63_16865 ENOG4105CHR reductase EKQ63_16895 ENOG4105ED2 Beta-lactamase EKQ63_16920 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) EKQ63_16930 ENOG4105C0R drug resistance transporter emrb qaca subfamily EKQ63_16990 ENOG4105K6H D-cysteine desulfhydrase EKQ63_17005 ENOG4108A04 Beta-lactamase EKQ63_17015 ENOG4105VZ8 Transcriptional regulator EKQ63_17035 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase EKQ63_17045 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) EKQ63_17065 ENOG4105JQZ Methyltransferase EKQ63_17085 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) EKQ63_17105 ENOG4105BZU Histidine kinase EKQ63_17115 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) EKQ63_17130 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A EKQ63_17145 ENOG4108JQ1 Dehydrogenase EKQ63_17200 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EKQ63_17250 ENOG4108ISG Major Facilitator EKQ63_17265 ENOG4107MII Sugar-specific transcriptional regulator TrmB EKQ63_17270 ENOG4105CZM Major Facilitator EKQ63_17285 ENOG4105CRW Short chain fatty acid transporter EKQ63_17295 ENOG4105DYS nad(p)h dehydrogenase (quinone) EKQ63_17325 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) EKQ63_17350 ENOG4108K8S endonuclease I EKQ63_17375 ENOG4108Z66 YbaK ebsC protein EKQ63_17385 ENOG4105KVH Transcriptional regulator EKQ63_17390 ENOG4108RCM Nitroreductase EKQ63_17410 ENOG4108PSK reductase EKQ63_17420 ENOG4105CJ1 ABC, transporter EKQ63_17480 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase EKQ63_17485 ENOG4105DKQ ROK family EKQ63_17495 ENOG4108UW5 maltose o-acetyltransferase EKQ63_17505 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EKQ63_17510 ENOG4105C31 Tryptophanyl-tRNA synthetase EKQ63_17535 ENOG4108R96 Methyltransferase, YaeB family EKQ63_17540 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) EKQ63_17550 ENOG4105EV4 Multidrug resistance protein mdtH EKQ63_17575 ENOG4105C37 (CBS) domain EKQ63_17590 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase EKQ63_17595 ENOG4105FAW cDP-glucose 4,6-dehydratase EKQ63_17630 ENOG4105DDN Pentapeptide repeat-containing protein EKQ63_17635 ENOG4105XDF Protein of unknown function (DUF1272) EKQ63_17640 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) EKQ63_17645 ENOG4105CMG Carbohydrate kinase EKQ63_17650 ENOG4105C6Z Gluconate EKQ63_17655 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EKQ63_17670 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EKQ63_17675 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EKQ63_17680 ENOG4105CIS alcohol dehydrogenase EKQ63_17685 ENOG41079Y2 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone EKQ63_17700 ENOG4105EWI Short-chain dehydrogenase reductase Sdr EKQ63_17720 ENOG41090KN UPF0303 protein EKQ63_17730 ENOG4105C44 Serine transporter EKQ63_17760 ENOG4108TZY GntR Family Transcriptional Regulator EKQ63_17765 ENOG4105D9R oxidoreductase EKQ63_17770 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase EKQ63_17775 ENOG4105KVH Transcriptional regulator EKQ63_17780 ENOG4105KVH Transcriptional regulator EKQ63_17820 ENOG4105JAB phenazine biosynthesis protein, phzf family EKQ63_17830 ENOG4105CHR reductase EKQ63_17840 ENOG4105KNA -acetyltransferase EKQ63_17850 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EKQ63_17855 ENOG4105KVH Transcriptional regulator EKQ63_17890 ENOG4105KAF membrAne EKQ63_17915 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) EKQ63_18025 ENOG4108TN2 lmbE family EKQ63_18035 ENOG4107R3E Citrate transporter EKQ63_18045 ENOG4108MES Periplasmic binding protein EKQ63_18050 ENOG4105EHG Permease protein EKQ63_18055 ENOG4105DQ5 transport system permease protein EKQ63_18060 ENOG4105NX3 Membrane EKQ63_18065 ENOG4105EYF MMPL domain protein EKQ63_18085 ENOG41068WN EKQ63_18090 ENOG4107CUJ Protein of unknown function (DUF2690) EKQ63_18100 ENOG4107V2S Transcriptional regulator EKQ63_18110 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EKQ63_18125 ENOG4105C98 muts2 protein EKQ63_18135 ENOG4105E5K Alpha-amylase EKQ63_18140 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase EKQ63_18145 ENOG4105DPN Oligoendopeptidase f EKQ63_18165 ENOG4105FFC UPF0187 protein EKQ63_18180 ENOG4108A04 Beta-lactamase EKQ63_18210 ENOG4107VXM glycerophosphoryl diester phosphodiesterase EKQ63_18220 ENOG41082BM Transcriptional regulator, arsr family EKQ63_18225 ENOG4105CIS alcohol dehydrogenase EKQ63_18235 ENOG4107JM4 Tetratricopeptide repeat EKQ63_18260 ENOG4105C09 Bile acid EKQ63_18265 ENOG4105CQB FAD linked oxidase domain protein EKQ63_18320 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) EKQ63_18325 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) EKQ63_18355 ENOG4108Z6Z Transcriptional regulator EKQ63_18365 ENOG41080V3 Major Facilitator superfamily EKQ63_18370 ENOG4105D3W isochorismatase EKQ63_18375 ENOG4105FS7 Transcriptional regulator EKQ63_18390 ENOG4105E1K spore germination protein EKQ63_18425 ENOG4105C26 Dehydrogenase EKQ63_18435 ENOG4105C19 ABC transporter EKQ63_18465 ENOG4107SDT Homocitrate synthase EKQ63_18485 ENOG4105D06 uba thif-type nad fad binding protein EKQ63_18515 ENOG4105KT7 mgtC SapB transporter EKQ63_18530 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase EKQ63_18535 ENOG4105EAB amino acid AbC transporter EKQ63_18545 ENOG4108HW4 amino acid AbC transporter EKQ63_18550 ENOG41073R8 VanW family EKQ63_18560 ENOG4108R1P EKQ63_18575 ENOG4105VEQ Cold shock protein EKQ63_18600 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) EKQ63_18620 ENOG410904N short-chain dehydrogenase reductase EKQ63_18630 ENOG4106IQC argininosuccinate lyase EKQ63_18645 ENOG4108IA2 Sodium pantothenate symporter EKQ63_18655 ENOG4105C26 Dehydrogenase EKQ63_18660 ENOG4105CHR reductase EKQ63_18670 ENOG4105EWU Squalene--hopene cyclase EKQ63_18680 ENOG4105FR1 rard protein EKQ63_18685 ENOG410696E Membrane EKQ63_18700 ENOG4105D1F ATP-binding protein EKQ63_18710 ENOG4108ZAF Molybdopterin EKQ63_18715 ENOG4105CVM Molybdenum cofactor synthesis domain protein EKQ63_18720 ENOG4105D06 uba thif-type nad fad binding protein EKQ63_18725 ENOG4105TMB Formate nitrite transporter EKQ63_18735 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) EKQ63_18740 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) EKQ63_18750 ENOG4108JB9 formate dehydrogenase EKQ63_18755 ENOG4105E1K spore germination protein EKQ63_18825 ENOG4107QJT sodium dicarboxylate symporter EKQ63_18830 ENOG4108KGH TRANSCRIPTIONal EKQ63_18840 ENOG4105EMN RNA polymerase sigma factor EKQ63_18855 ENOG4105CIG ABC transporter EKQ63_18875 ENOG4105D9R oxidoreductase EKQ63_18885 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EKQ63_18890 ENOG4105K4P CoA-binding domain protein EKQ63_18895 ENOG4105C0H protease EKQ63_18900 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_18910 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase EKQ63_18920 ENOG4105W8X HesB YadR YfhF-family protein EKQ63_18955 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) EKQ63_18965 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EKQ63_18975 ENOG4105BZ1 (ABC) transporter EKQ63_18980 ENOG4108I0Z Aconitate hydratase EKQ63_19010 ENOG4105E5W Transporter EKQ63_19020 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) EKQ63_19040 ENOG4107F3J Amp-dependent synthetase and ligase EKQ63_19045 ENOG4107ZYJ bioY protein EKQ63_19050 ENOG4105CEY Amp-dependent synthetase and ligase EKQ63_19065 ENOG4108IMY Transcriptional regulator EKQ63_19085 ENOG4105D9G High-affinity EKQ63_19090 ENOG4105IW1 AmiS UreI transporter EKQ63_19105 ENOG4108YH3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) EKQ63_19145 ENOG4107AYK membrAne EKQ63_19160 ENOG4105BZU Histidine kinase EKQ63_19165 ENOG4105FBA Phospholipase Carboxylesterase EKQ63_19170 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase EKQ63_19185 ENOG4105CBC glutamate synthase EKQ63_19190 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EKQ63_19195 ENOG4108VJ1 Transcriptional regulator (CarD family EKQ63_19200 ENOG4108903 Formimidoylglutamase EKQ63_19225 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) EKQ63_19260 ENOG4107QIV Cytochrome c biogenesis protein EKQ63_19275 ENOG4105CH2 amidohydrolase EKQ63_19285 ENOG4105CJ1 ABC, transporter EKQ63_19300 ENOG4107RSM transcriptional regulator EKQ63_19310 ENOG41067MG lrgb family EKQ63_19330 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EKQ63_19350 ENOG4105BZ1 (ABC) transporter EKQ63_19355 ENOG4105BZ1 (ABC) transporter EKQ63_19390 ENOG4108HW3 (ABC) transporter EKQ63_19395 ENOG4105CGH 5'-nucleotidase EKQ63_19405 ENOG4108SVB resolvase EKQ63_19425 ENOG4105K7K Transcriptional regulator EKQ63_19445 ENOG4108IBT Inherit from COG: transposase EKQ63_19470 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EKQ63_19645 ENOG41087GE Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity) EKQ63_19750 ENOG4105C5F glutamine synthetase EKQ63_19755 ENOG4105KV4 Transcriptional regulator EKQ63_19760 ENOG4105CXI aluminum resistance protein EKQ63_19765 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EKQ63_19770 ENOG4105EN6 Membrane EKQ63_19775 ENOG4106F1P AAA ATPase, central domain protein EKQ63_19805 ENOG41069ER domain protein EKQ63_19810 ENOG4105DM4 PTS System EKQ63_19815 ENOG4105DE4 1-phosphofructokinase EKQ63_19820 ENOG4105E98 transcriptional regulator DeoR family EKQ63_19825 ENOG4107QW4 alcohol dehydrogenase EKQ63_19830 ENOG4108SJC Membrane EKQ63_19840 ENOG4105C85 amino acid EKQ63_19860 ENOG4105TMB Formate nitrite transporter EKQ63_19865 ENOG4105K70 DNA-binding protein EKQ63_19875 ENOG4105C59 p-type ATPase EKQ63_19880 ENOG410681U heavy metal transport detoxification protein EKQ63_19885 ENOG4105VPX protein, conserved in bacteria EKQ63_19895 ENOG4105NIV Esterase EKQ63_19900 ENOG4105E0A ABC, transporter EKQ63_19920 ENOG4105CGK Exodeoxyribonuclease III EKQ63_19930 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EKQ63_19935 ENOG4105D03 DNA-3-methyladenine glycosylase II EKQ63_19965 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase EKQ63_19970 ENOG4105BZU Histidine kinase EKQ63_19990 ENOG41067MG lrgb family EKQ63_20030 ENOG4105F0V Cell wall hydrolase EKQ63_20045 ENOG4105E0M Sulfatase EKQ63_20050 ENOG410890F Dynamin family EKQ63_20060 ENOG4107QHE Choloylglycine hydrolase EKQ63_20090 ENOG4105DQU oxidoreductase, subunit beta EKQ63_20095 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein EKQ63_20100 ENOG4108IGT Dipeptidase EKQ63_20105 ENOG4105MCT stage V sporulation protein S EKQ63_20110 ENOG4105D48 metallophosphoesterase EKQ63_20115 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) EKQ63_20130 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase EKQ63_20145 ENOG4105XZV Protein of unknown function (DUF3243) EKQ63_20150 ENOG4108RKS Short-chain dehydrogenase reductase Sdr EKQ63_20170 ENOG4105UIB (ABC) transporter EKQ63_20175 ENOG4108JQ9 ABC transporter EKQ63_20180 ENOG4105DIH basic membrane EKQ63_20185 ENOG4105FDP GntR family transcriptional regulator EKQ63_20195 ENOG4107QZI cell division protein FtsK EKQ63_20205 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit EKQ63_20220 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) EKQ63_20230 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EKQ63_20235 ENOG4108S0H Dipicolinic acid synthetase, b subunit EKQ63_20240 ENOG4105E35 Dipicolinate synthase subunit A EKQ63_20250 ENOG4105C1V Peptidase, M16 EKQ63_20270 ENOG4105DTN riboflavin biosynthesis protein ribF EKQ63_20285 ENOG4105W7A Protein of unknown function (DUF503) EKQ63_20295 ENOG4105VHM ribosomal protein EKQ63_20300 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination EKQ63_20305 ENOG4105CHV Transcription elongation factor NusA EKQ63_20315 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) EKQ63_20325 ENOG4105DZP Membrane-associated zinc metalloprotease EKQ63_20335 ENOG4105KNE Phosphatidate cytidylyltransferase EKQ63_20380 ENOG4108HE4 integrase family EKQ63_20390 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EKQ63_20395 ENOG4105C79 DNA protecting protein DprA EKQ63_20400 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EKQ63_20415 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) EKQ63_20440 ENOG4105VB6 UPF0109 protein EKQ63_20460 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EKQ63_20465 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) EKQ63_20480 ENOG4105CHR reductase EKQ63_20485 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EKQ63_20500 ENOG4105CB5 ATP-dependent DNA helicase recG EKQ63_20505 ENOG4105DP4 dak2 domain fusion protein ylov EKQ63_20510 ENOG4108ZAA Alkaline-shock protein EKQ63_20525 ENOG4105FJ0 thiamine EKQ63_20530 ENOG4105DJV ribulose-phosphate 3-epimerase EKQ63_20540 ENOG4105D9P serine threonine protein kinase EKQ63_20545 ENOG4108ZF3 Phosphatase EKQ63_20555 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B EKQ63_20565 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EKQ63_20570 ENOG4105C25 Primosomal protein n' EKQ63_20575 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EKQ63_20595 ENOG4105DSJ YicC domain protein EKQ63_20605 ENOG4105F23 Fibronectin-binding protein EKQ63_20610 ENOG4105DC7 peptidase M24 EKQ63_20690 ENOG4105C34 Pseudouridine synthase EKQ63_20715 ENOG4105DBK s4 domain protein EKQ63_20720 ENOG41067XK integral membrane protein EKQ63_20730 ENOG4105DFA alanine racemase domain protein EKQ63_20735 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EKQ63_20740 ENOG4105WR5 sporulation protein, YlmC YmxH family EKQ63_20750 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EKQ63_20760 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EKQ63_20765 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EKQ63_20770 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) EKQ63_20785 ENOG4105CNI cell division protein FtsW EKQ63_20800 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EKQ63_20805 ENOG4105CJN penicillin-binding protein EKQ63_20810 ENOG4105CJN penicillin-binding protein EKQ63_20815 ENOG41068DC Essential cell division protein (By similarity) EKQ63_20850 ENOG4105KNH Nucleic acid-binding protein EKQ63_20860 ENOG41063PX domain protein EKQ63_20865 ENOG4105D78 K07001 NTE family protein EKQ63_20870 ENOG4105H20 Sporulation integral membrane protein YlbJ EKQ63_20880 ENOG4106H78 methyltransferase EKQ63_20900 ENOG4107TB6 phosphoglycerate mutase EKQ63_20915 ENOG4106UY4 Inherit from COG: Scp-like extracellular EKQ63_20965 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) EKQ63_20975 ENOG4105CNI cell division protein FtsW EKQ63_20990 ENOG4108IAB Phoh family EKQ63_21010 ENOG4105QA2 EKQ63_21015 ENOG4105CI3 gtp-binding protein typa EKQ63_21025 ENOG4105ECY inositol monophosphatase EKQ63_21045 ENOG4105CXN decarboxylase EKQ63_21095 ENOG4105CPP Dehydrogenase, E1 component EKQ63_21110 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) EKQ63_21115 ENOG4108X4Q Hydrolase EKQ63_21130 ENOG4105CN5 Metallo-Beta-Lactamase EKQ63_21135 ENOG4107ZYR domain protein EKQ63_21170 ENOG4108XRC Protein of unknown function (DUF458) EKQ63_21175 ENOG4107IN1 Protein of unknown function (DUF1797) EKQ63_21190 ENOG4105EPM Diguanylate phosphodiesterase EKQ63_21195 ENOG4105K6S Short-chain dehydrogenase reductase Sdr EKQ63_21210 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) EKQ63_21220 ENOG4105UIN EKQ63_21275 ENOG4108HGU Histidine kinase EKQ63_21285 ENOG4105CHM Aminotransferase EKQ63_21290 ENOG4105FKQ transcriptional regulator EKQ63_21295 ENOG4105EG2 ABC transporter, permease EKQ63_21305 ENOG4107FKK extracellular solute-binding protein family 1 EKQ63_21315 ENOG4105CG3 alpha amylase, catalytic region EKQ63_21365 ENOG4105CHU acetyl-coa acetyltransferase EKQ63_21400 ENOG4105K7K Transcriptional regulator EKQ63_21405 ENOG4105DTD Dehydrogenase EKQ63_21425 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase EKQ63_21465 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase EKQ63_21475 ENOG4106TD9 Diguanylate cyclase EKQ63_21495 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EKQ63_21510 ENOG4105CID antiterminator EKQ63_21520 ENOG4105FDP GntR family transcriptional regulator EKQ63_21530 ENOG4105CE4 GlcNAc 6-P deacetylase EKQ63_21575 ENOG4107ZE5 PPIases accelerate the folding of proteins EKQ63_21580 ENOG4105PTM secreted protein EKQ63_21585 ENOG4105J7I hydrolase EKQ63_21595 ENOG4105G6R Stage v sporulation protein ae EKQ63_21605 ENOG4105CZ3 stage V sporulation protein ad EKQ63_21610 ENOG41090VF Stage v sporulation protein ac EKQ63_21630 ENOG4105C8J )-transporter EKQ63_21635 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EKQ63_21645 ENOG41082AN stage II sporulation protein EKQ63_21650 ENOG4105DZ1 carboxypeptidase EKQ63_21660 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family EKQ63_21665 ENOG4105DVE abc transporter atp-binding protein EKQ63_21700 ENOG4105D7N magnesium and cobalt transport protein CorA EKQ63_21725 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EKQ63_21735 ENOG4105I3K Ferric uptake regulator, Fur family EKQ63_21740 ENOG4105MZ9 stage II sporulation protein m EKQ63_21760 ENOG4105CPC Aldo Keto reductase EKQ63_21770 ENOG4105RHY Pfam:UPF0157 EKQ63_21790 ENOG4107SKW Inherit from COG: Alpha beta hydrolase EKQ63_21800 ENOG4105ETE Transcriptional regulator (LacI family EKQ63_21805 ENOG4108YM7 Gcn5-related n-acetyltransferase EKQ63_21825 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EKQ63_21830 ENOG4108R6K riboflavin synthase, subunit alpha EKQ63_21855 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EKQ63_21860 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EKQ63_21875 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) EKQ63_21885 ENOG4105DFD Na H antiporter EKQ63_21890 ENOG4105CGH 5'-nucleotidase EKQ63_21945 ENOG4108IXY short-chain dehydrogenase reductase EKQ63_21950 ENOG41069FQ Metallo-beta-lactamase superfamily EKQ63_21955 ENOG4105II7 pyrroline-5-carboxylate reductase EKQ63_21960 ENOG4105EJQ L-serine dehydratase EKQ63_21980 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EKQ63_21990 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) EKQ63_22000 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) EKQ63_22005 ENOG4105D9U N-acetyltransferase EKQ63_22015 ENOG4108VZI ErfK ybiS ycfS ynhG family protein EKQ63_22020 ENOG4108QEG Membrane EKQ63_22025 ENOG4105CDA abc transporter atp-binding protein EKQ63_22030 ENOG4105E5Q amino acid AbC transporter EKQ63_22035 ENOG4108HW3 (ABC) transporter EKQ63_22055 ENOG4108QY0 Membrane EKQ63_22070 ENOG4105C7S Dehydrogenase EKQ63_22075 ENOG4105CPP Dehydrogenase, E1 component EKQ63_22095 ENOG4107RDP Dehydrogenase EKQ63_22110 ENOG4108JUB Transcriptional regulator EKQ63_22120 ENOG4108QXE glycerophosphoryl diester phosphodiesterase EKQ63_22130 ENOG4107QQR Sporulation EKQ63_22140 ENOG4105S1Z Stage IV sporulation protein B EKQ63_22145 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EKQ63_22155 ENOG4105DX0 Hemolysin A EKQ63_22165 ENOG4105CTB Polyprenyl synthetase EKQ63_22190 ENOG4108ZSR alkaline shock protein EKQ63_22195 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EKQ63_22220 ENOG410644B Stage III sporulation protein af EKQ63_22230 ENOG4105KQ4 Stage iii sporulation protein ad EKQ63_22235 ENOG4108CQH stage III sporulation protein AC EKQ63_22240 ENOG4105KR5 Stage iii sporulation protein EKQ63_22245 ENOG4105CD2 stage iii sporulation protein aa EKQ63_22270 ENOG4105DC7 peptidase M24 EKQ63_22285 ENOG4105CBJ Metal-dependent enzyme EKQ63_22295 ENOG4107YBY Hydrolase EKQ63_22325 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) EKQ63_22330 ENOG4105WZW rhodanese family EKQ63_22355 ENOG41080TC multidrug resistance protein EKQ63_22390 ENOG4105CJ1 ABC, transporter EKQ63_22395 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family EKQ63_22430 ENOG4105C0D helicase EKQ63_22490 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase EKQ63_22675 ENOG4105KRN Transcriptional regulator, abrb family EKQ63_22685 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) EKQ63_22690 ENOG4105YQ0 EKQ63_22730 ENOG4105VTR Integrase EKQ63_22815 ENOG4105D7V transposase EKQ63_22825 ENOG4105C3R Methionine synthase EKQ63_22835 ENOG4105C28 cystathionine EKQ63_22840 ENOG4105C28 cystathionine EKQ63_22860 ENOG4105C5X domain protein EKQ63_22870 ENOG4105DKQ ROK family EKQ63_22880 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EKQ63_22895 ENOG4108UTW Plays a role in the regulation of phosphate uptake EKQ63_22900 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) EKQ63_22905 ENOG4105E2Z phosphate ABC transporter (Permease EKQ63_22910 ENOG4105C8U phosphate abc transporter EKQ63_22915 ENOG4105PWN phosphate abc transporter EKQ63_22920 ENOG4107RF6 penicillin-binding protein EKQ63_22930 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EKQ63_22955 ENOG4105N80 Ferric uptake regulator, Fur family EKQ63_22965 ENOG4105FDK ABC transporter EKQ63_22970 ENOG4108JYZ YitT family EKQ63_22975 ENOG41069ZM Protein of unknown function (DUF2624) EKQ63_23000 ENOG4105EGD dinuclear metal center protein, YbgI family EKQ63_23015 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EKQ63_23020 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EKQ63_23045 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) EKQ63_23050 ENOG4105KG3 cytidine deaminase EKQ63_23055 ENOG4107YR5 Diacylglycerol kinase EKQ63_23065 ENOG4105CTJ Metal Dependent Phosphohydrolase EKQ63_23070 ENOG4105C9A Phoh family EKQ63_23080 ENOG41068P3 sporulation protein YqfC EKQ63_23085 ENOG4105KTH gatB Yqey EKQ63_23100 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) EKQ63_23105 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EKQ63_23125 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ EKQ63_23135 ENOG4105CSA Coproporphyrinogen iii oxidase EKQ63_23140 ENOG4105KVH Transcriptional regulator EKQ63_23165 ENOG4105TQK DNA polymerase iii, delta' subunit EKQ63_23175 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 EKQ63_23180 ENOG4108UK2 deaminase EKQ63_23185 ENOG4105KQC Competence protein EKQ63_23195 ENOG4105DXX methyltransferase EKQ63_23205 ENOG4108WF2 Metal Dependent Phosphohydrolase EKQ63_23215 ENOG410812S Rna-binding protein EKQ63_23225 ENOG4105CQW ribosome biogenesis GTPase YqeH EKQ63_23230 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase EKQ63_23245 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EKQ63_23265 ENOG4108TVJ Nitroreductase EKQ63_23280 ENOG4105G6Z alkaline phosphatase EKQ63_23285 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EKQ63_23290 ENOG4108MUZ hydrolase EKQ63_23325 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin EKQ63_23330 ENOG4105MIR Phenylalanine 4-monooxygenase EKQ63_23340 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase EKQ63_23380 ENOG4105S6R Iron-hydroxamate transporter permease subunit EKQ63_23385 ENOG4108HUF Transporter EKQ63_23395 ENOG4108EKI Dehydrogenase EKQ63_23400 ENOG4105C28 cystathionine EKQ63_23430 ENOG4107XRG penicillin-binding protein EKQ63_23445 ENOG4105CFP Peptidase U32 EKQ63_23450 ENOG4105XYU peptidase (U32 family) EKQ63_23455 ENOG4108VQJ O-methyltransferase EKQ63_23460 ENOG4105HHA aminodeoxychorismate lyase EKQ63_23490 ENOG4105C02 permease EKQ63_23505 ENOG41060CR EKQ63_23510 ENOG4105C7H Helicase, RecD TraA family EKQ63_23525 ENOG4105C3J Cysteine desulfurase EKQ63_23535 ENOG4105D1H recombination factor protein RarA EKQ63_23540 ENOG4108VCI transcription factor, rsfa family EKQ63_23550 ENOG4105CUZ uba thif-type nad fad binding protein EKQ63_23560 ENOG4105CUT histidyl-tRNA synthetase EKQ63_23570 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EKQ63_23580 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EKQ63_23585 ENOG41076HS cation diffusion facilitator family transporter EKQ63_23590 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EKQ63_23600 ENOG4105CKP Polysaccharide Biosynthesis Protein EKQ63_23605 ENOG4108QG2 Membrane EKQ63_23615 ENOG4105VIE preprotein translocase, subunit YajC EKQ63_23630 ENOG41061AI Protein of unknown function (DUF2905) EKQ63_23650 ENOG4108IPJ Membrane EKQ63_23655 ENOG41082BM Transcriptional regulator, arsr family EKQ63_23680 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EKQ63_23685 ENOG4108IYU L-aspartate oxidase EKQ63_23700 ENOG4108RPX mosc domain containing protein EKQ63_23705 ENOG4105CQC Prephenate dehydratase EKQ63_23725 ENOG4105EWM Histidine kinase EKQ63_23735 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control EKQ63_23755 ENOG4105C03 ribonuclease EKQ63_23770 ENOG4107QMS site-determining protein EKQ63_23785 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EKQ63_23790 ENOG4105DFF Rod shape-determining protein mreb EKQ63_23815 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EKQ63_23830 ENOG41068KH stage VI sporulation protein D EKQ63_23840 ENOG4105D52 delta-aminolevulinic acid dehydratase EKQ63_23865 ENOG4105K56 Transcriptional regulator EKQ63_23885 ENOG4108IUQ atp-dependent protease EKQ63_23910 ENOG4108QCI YvbH-like oligomerisation region EKQ63_23940 ENOG4105M59 Phosphodiesterase, mj0936 family EKQ63_23945 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) EKQ63_23955 ENOG4108XJQ germination protein EKQ63_23965 ENOG4108PCX Major Facilitator EKQ63_23975 ENOG4105KBX Transcriptional regulator, TetR family EKQ63_23990 ENOG4105PFC Transcriptional regulator EKQ63_24000 ENOG4105DZC cytosine deaminase EKQ63_24005 ENOG41067S9 phage shock protein C, PspC EKQ63_24010 ENOG4108JCI Transcriptional regulator EKQ63_24020 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) EKQ63_24025 ENOG4108Z40 Transcriptional regulator EKQ63_24030 ENOG4105RHA ABC transporter, permease EKQ63_24035 ENOG4108IUX (ABC) transporter EKQ63_24040 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family EKQ63_24045 ENOG4105ER2 Ompa motb domain protein EKQ63_24050 ENOG4105E14 MotA TolQ exbB proton channel EKQ63_24055 ENOG4108VXD carboxy-peptidase EKQ63_24065 ENOG4105E33 succinate dehydrogenase EKQ63_24075 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit EKQ63_24090 ENOG4105K63 Thioredoxin EKQ63_24095 ENOG4105C10 Electron transfer flavoprotein EKQ63_24100 ENOG4105BZJ Electron transfer flavoprotein EKQ63_24105 ENOG41060WC Enoyl-CoA hydratase EKQ63_24110 ENOG4107Z3H Transcriptional regulator, TetR family EKQ63_24115 ENOG4105CEY Amp-dependent synthetase and ligase EKQ63_24160 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EKQ63_24170 ENOG4105DR4 Methyltransferase EKQ63_24180 ENOG4105KFN sortase, SrtB family EKQ63_24185 ENOG4105E0A ABC, transporter EKQ63_24200 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) EKQ63_24205 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) EKQ63_24215 ENOG4105FE9 pseudouridine synthase EKQ63_24225 ENOG4105DCG PHP domain protein EKQ63_24260 ENOG4105C5S asparaginyl-tRNA synthetase EKQ63_24270 ENOG4105EQ0 Major Facilitator superfamily EKQ63_24275 ENOG4108Z8I decarboxylase EKQ63_24280 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) EKQ63_24290 ENOG4108RWN rrna methyltransferase EKQ63_24310 ENOG4105C0R drug resistance transporter emrb qaca subfamily EKQ63_24315 ENOG4105CW7 secretion protein, HlyD family EKQ63_24320 ENOG4108JGH Tetr family transcriptional regulator EKQ63_24325 ENOG4105CN9 Peptidase m42 family protein EKQ63_24345 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) EKQ63_24350 ENOG4105C22 threonyL-tRNA synthetase EKQ63_24355 ENOG4108TDW sporulation protein YtxC EKQ63_24375 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) EKQ63_24380 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase EKQ63_24385 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EKQ63_24400 ENOG4105C2M dna polymerase I EKQ63_24405 ENOG4105BZU Histidine kinase EKQ63_24410 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EKQ63_24430 ENOG4108HMX isocitrate dehydrogenase (NADP) EKQ63_24435 ENOG4105BZN citrate synthase EKQ63_24450 ENOG4108REF Sporulation integral membrane protein ytvi EKQ63_24455 ENOG4105FS0 cytoplasmic membrane protein EKQ63_24480 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family EKQ63_24485 ENOG4105C6K Malic enzyme EKQ63_24490 ENOG4105C0B DNA polymerase III (alpha subunit) EKQ63_24495 ENOG4105VV2 EKQ63_24505 ENOG4105SFS phosphoesterase RecJ domain protein EKQ63_24540 ENOG4105DC7 peptidase M24 EKQ63_24585 ENOG41082W1 Cupin 2, conserved barrel domain protein EKQ63_24605 ENOG4107YZX Universal stress protein EKQ63_24645 ENOG4108JYZ YitT family EKQ63_24675 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) EKQ63_24680 ENOG4105KBJ sporulation protein ytfj EKQ63_24695 ENOG4105EFZ amidohydrolase EKQ63_24705 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) EKQ63_24730 ENOG4105C5Q Transcriptional regulator EKQ63_24740 ENOG4105U5Y Transcriptional regulator EKQ63_24750 ENOG4105C28 cystathionine EKQ63_24780 ENOG4105EMN RNA polymerase sigma factor EKQ63_24800 ENOG4105F1V Acetoin utilization protein EKQ63_24805 ENOG4105W87 Cbs domain EKQ63_24810 ENOG4105DGU Histone deacetylase EKQ63_24815 ENOG4106HB6 Alpha beta hydrolase EKQ63_24825 ENOG4105EP9 oxidoreductase EKQ63_24855 ENOG4105ETE Transcriptional regulator (LacI family EKQ63_24880 ENOG4105C88 aminopeptidase EKQ63_24910 ENOG4108IPJ Membrane EKQ63_24920 ENOG4105K7K Transcriptional regulator EKQ63_24960 ENOG4108VDD TRNA binding domain protein EKQ63_24990 ENOG4105C8F Beta-lactamase domain protein EKQ63_25005 ENOG4108V15 phosphotransferase enzyme family EKQ63_25010 ENOG4108IUM Glycogen debranching enzyme EKQ63_25020 ENOG4107QSE Dipeptidase EKQ63_25025 ENOG4105YW5 deoR family transcriptional regulator EKQ63_25040 ENOG4105CBX hi0933 family EKQ63_25080 ENOG4108VJ1 Transcriptional regulator (CarD family EKQ63_25085 ENOG4107EXU Short-chain dehydrogenase reductase Sdr EKQ63_25105 ENOG4108ZAF Molybdopterin EKQ63_25110 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein EKQ63_25115 ENOG4105CVM Molybdenum cofactor synthesis domain protein EKQ63_25125 ENOG4105D06 uba thif-type nad fad binding protein EKQ63_25130 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EKQ63_25155 ENOG41085GJ domain protein EKQ63_25165 ENOG4105DWV Homoserine O-trans-acetylase EKQ63_25175 ENOG4108B31 Spore germination protein EKQ63_25205 ENOG410605W Major Facilitator EKQ63_25210 ENOG4107S91 Sodium hydrogen exchanger EKQ63_25215 ENOG4105NCW Trka-c domain protein EKQ63_25235 ENOG4105C19 ABC transporter EKQ63_25255 ENOG4105N5T Radical SAM Protein EKQ63_25270 ENOG4105CIG ABC transporter EKQ63_25310 ENOG4105E8V Alpha Beta Hydrolase Fold protein EKQ63_25315 ENOG4108Z0R Transferase EKQ63_25320 ENOG4105YVM Phosphoesterase, PA-phosphatase related EKQ63_25325 ENOG4105BZF Glycosyl transferase (Group 1 EKQ63_25335 ENOG4108RIR Molybdenum cofactor biosynthesis protein EKQ63_25345 ENOG4108MK9 spermidine N(1)-acetyltransferase EKQ63_25385 ENOG4105EGD dinuclear metal center protein, YbgI family EKQ63_25405 ENOG4105BZU Histidine kinase EKQ63_25410 ENOG4105BZU Histidine kinase EKQ63_25415 ENOG4107S9D Alpha beta hydrolase EKQ63_25420 ENOG4107T7U Sulfatase EKQ63_25440 ENOG4105D2X ABC transporter substrate-binding protein EKQ63_25450 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component EKQ63_25510 ENOG4108V2W Carbonate dehydratase EKQ63_25515 ENOG4105C4M (Ubiquinol oxidase) subunit I EKQ63_25520 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EKQ63_25565 ENOG41087YS Phage shock protein A EKQ63_25615 ENOG4105BZU Histidine kinase EKQ63_25620 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_25645 ENOG4108UGV hypoxanthine phosphoribosyltransferase EKQ63_25650 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) EKQ63_25670 ENOG4107ZTW SNARE associated Golgi EKQ63_25675 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) EKQ63_25685 ENOG4105C19 ABC transporter EKQ63_25690 ENOG41086D8 Transcriptional regulator EKQ63_25700 ENOG41082BM Transcriptional regulator, arsr family EKQ63_25750 ENOG4105C6Z Gluconate EKQ63_25755 ENOG4105FDP GntR family transcriptional regulator EKQ63_25775 ENOG41069H0 dihydroorotase EC 3.5.2.3 EKQ63_25795 ENOG4105DTQ mandelate racemase muconate lactonizing EKQ63_25805 ENOG4108IPT Naphthoate synthase EKQ63_25810 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) EKQ63_25820 ENOG4105E4F Isochorismate synthase EKQ63_25825 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase EKQ63_25835 ENOG4105VEQ Cold shock protein EKQ63_25885 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin EKQ63_25895 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) EKQ63_25990 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation EKQ63_26015 ENOG4105KT7 mgtC SapB transporter EKQ63_26020 ENOG4107PBV potassium channel EKQ63_26040 ENOG4105WG9 Conserved Protein EKQ63_26050 ENOG4105CHM Aminotransferase EKQ63_26055 ENOG4108ZB6 transcriptional regulator AsnC family EKQ63_26060 ENOG4105C5I Dehydrogenase EKQ63_26065 ENOG4108MUZ hydrolase EKQ63_26075 ENOG4105C87 Aminotransferase class I and II EKQ63_26085 ENOG4105Y38 Kinase-associated protein B EKQ63_26095 ENOG4107R3E Citrate transporter EKQ63_26110 ENOG4105D9H Catalyzes the attachment of glycine to tRNA(Gly) (By similarity) EKQ63_26115 ENOG4105KA0 thioesterase Superfamily protein EKQ63_26135 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EKQ63_26155 ENOG41069ER domain protein EKQ63_26170 ENOG4105CEP NADH dehydrogenase EKQ63_26195 ENOG4105EWC Purine nucleoside phosphorylase EKQ63_26215 ENOG4108YX9 iron--sulfur cluster insertion protein erpA EKQ63_26245 ENOG4105C4B ABC transporter, permease EKQ63_26255 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EKQ63_26275 ENOG41083MR nifu domain-containing protein EKQ63_26290 ENOG4108W5N phosphatidylglycerophosphatase a EKQ63_26310 ENOG4105DAX Pfam:DUF2983 EKQ63_26320 ENOG4105DYS nad(p)h dehydrogenase (quinone) EKQ63_26330 ENOG4105D4U had-superfamily hydrolase, subfamily iia EKQ63_26345 ENOG4105CBT Fructose-1,6-bisphosphatase EKQ63_26360 ENOG4105MMD transcriptional regulator EKQ63_26365 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) EKQ63_26370 ENOG4107TXC Transcriptional regulator EKQ63_26375 ENOG41090T1 Membrane EKQ63_26400 ENOG4105FAA peptidase M23 EKQ63_26410 ENOG4105KZD Domain of unknown function (DUF1805) EKQ63_26415 ENOG4107R8B 5'-nucleotidase EKQ63_26435 ENOG4105DIW FeS assembly protein SUFB EKQ63_26440 ENOG4108UNV SUF system FeS assembly protein, NifU family EKQ63_26445 ENOG4105C9B Cysteine desulfurase EKQ63_26450 ENOG4105JRK feS assembly protein SufD EKQ63_26455 ENOG4105C3K feS assembly ATPase SufC EKQ63_26460 ENOG4105D01 (LipO)protein EKQ63_26465 ENOG4105D01 (LipO)protein EKQ63_26470 ENOG4108UMI ABC transporter, permease EKQ63_26505 ENOG41080E8 Transcriptional regulator, Spx MgsR family EKQ63_26530 ENOG4105VUC UPF0237 protein EKQ63_26585 ENOG4108W8B Beta-lactamase domain protein EKQ63_26590 ENOG4105C1G acyl-Coa dehydrogenase EKQ63_26595 ENOG4105CHU acetyl-coa acetyltransferase EKQ63_26610 ENOG4105DZ1 carboxypeptidase EKQ63_26630 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer EKQ63_26655 ENOG4108SUT Major Facilitator Superfamily EKQ63_26660 ENOG4107R7I amino acid EKQ63_26675 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EKQ63_26685 ENOG4107AYK membrAne EKQ63_26720 ENOG4107ZTW SNARE associated Golgi EKQ63_26730 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EKQ63_26735 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_26740 ENOG4105BZU Histidine kinase EKQ63_26760 ENOG4105C8Q Methyl-accepting chemotaxis EKQ63_26765 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer EKQ63_26770 ENOG4105VG1 fes assembly suf system protein EKQ63_26775 ENOG4105D4Y metalloprotease EKQ63_26795 ENOG4107T5V SNARE associated Golgi EKQ63_26800 ENOG4107S91 Sodium hydrogen exchanger EKQ63_26805 ENOG4105NCW Trka-c domain protein EKQ63_26815 ENOG4108RMU ferritin dps family protein EKQ63_26830 ENOG4108URH decarboxylase EKQ63_26850 ENOG4105D9N nucleoside EKQ63_26855 ENOG4105D9N nucleoside EKQ63_26870 ENOG4108RYK Nad-dependent epimerase dehydratase EKQ63_26885 ENOG4105CV8 reductase EKQ63_26890 ENOG4105F27 Major Facilitator EKQ63_26895 ENOG4105KVH Transcriptional regulator EKQ63_26910 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) EKQ63_26915 ENOG4105D4A Cell wall formation (By similarity) EKQ63_26940 ENOG4105C8Q Methyl-accepting chemotaxis EKQ63_26975 ENOG4105C5H ABC transporter EKQ63_26980 ENOG4108MK9 spermidine N(1)-acetyltransferase EKQ63_26985 ENOG4108VY7 phosphate-starvation-inducible protein PsiE EKQ63_26990 ENOG4105KVH Transcriptional regulator EKQ63_27010 ENOG4108V2W Carbonate dehydratase EKQ63_27015 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) EKQ63_27030 ENOG4108IPW abc transporter atp-binding protein EKQ63_27035 ENOG4105CM4 permease protein EKQ63_27080 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EKQ63_27090 ENOG4105XZU Preprotein translocase, subunit SecG EKQ63_27095 ENOG41067MG lrgb family EKQ63_27115 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) EKQ63_27145 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EKQ63_27165 ENOG41090VF Stage v sporulation protein ac EKQ63_27170 ENOG4105CZ3 stage V sporulation protein ad EKQ63_27185 ENOG4108QY0 Membrane EKQ63_27190 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) EKQ63_27200 ENOG4105KRI phosphocarrier protein (HPr EKQ63_27210 ENOG4105CHW UPF0052 protein EKQ63_27220 ENOG4108Z4K mutator MutT protein EKQ63_27230 ENOG4105C3M thioredoxin reductase EKQ63_27240 ENOG4108S4C acetyltransferase EKQ63_27260 ENOG41086DT Membrane protein of unknown function EKQ63_27275 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EKQ63_27280 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) EKQ63_27290 ENOG4107TXC Transcriptional regulator EKQ63_27320 ENOG4105HMI Membrane EKQ63_27325 ENOG4105DUM transcriptional regulator, lysR family EKQ63_27335 ENOG4108WS4 fmn reductase EKQ63_27355 ENOG4105BZ1 (ABC) transporter EKQ63_27365 ENOG4105CN1 protease EKQ63_27370 ENOG4105CRP Part of the ABC transporter FtsEX involved in EKQ63_27375 ENOG4105CAK Cell division ATP-binding protein ftsE EKQ63_27395 ENOG4105MS2 ribosomal subunit Interface protein EKQ63_27400 ENOG4105VEQ Cold shock protein EKQ63_27405 ENOG41081UC Inherit from COG: Competence protein EKQ63_27420 ENOG4105KVH Transcriptional regulator EKQ63_27430 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein EKQ63_27435 ENOG4108KGH TRANSCRIPTIONal EKQ63_27440 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase EKQ63_27445 ENOG4105C6Y Udp-glucose 6-dehydrogenase EKQ63_27450 ENOG4105ESV Glycosyl transferase, family 4 EKQ63_27460 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EKQ63_27480 ENOG4105F8D glycoside hydrolase family 4 EKQ63_27485 ENOG4105VCP PTS System EKQ63_27490 ENOG4105CK1 PTS System EKQ63_27500 ENOG4105VCP PTS System EKQ63_27510 ENOG4105VZJ PTS System EKQ63_27525 ENOG41090KQ Glyoxalase Bleomycin resistance protein (Dioxygenase EKQ63_27530 ENOG4105ECB domain protein EKQ63_27535 ENOG4107RSM transcriptional regulator EKQ63_27565 ENOG4105DAA L-lactate EKQ63_27575 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) EKQ63_27590 ENOG4105E0M Sulfatase EKQ63_27615 ENOG4107R8N Glycosyl transferase, family 2 EKQ63_27620 ENOG4105C94 Transporter EKQ63_27630 ENOG41069ER domain protein EKQ63_27655 ENOG4105KBK Zinc finger, swim domain protein EKQ63_27660 ENOG4105C0D helicase EKQ63_27690 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EKQ63_27700 ENOG4107RBB ABC transporter, permease EKQ63_27705 ENOG4105C19 ABC transporter EKQ63_27725 ENOG4105CXY transporter EKQ63_27740 ENOG41062D9 Histidine kinase EKQ63_27745 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_27750 ENOG4105CMR udp-glucose 4-epimerase EKQ63_27800 ENOG4107R8N Glycosyl transferase, family 2 EKQ63_27805 ENOG4105D7W serine acetyltransferase EKQ63_27810 ENOG4105D3Q Sugar transferase EKQ63_27815 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EKQ63_27825 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EKQ63_27830 ENOG4108RB3 Capsular polysaccharide biosynthesis protein EKQ63_27835 ENOG4107YJ4 chain length determinant protein EKQ63_27840 ENOG4105HTX biosynthesis protein EKQ63_27845 ENOG4107YJ4 chain length determinant protein EKQ63_27860 ENOG4105MT0 Sporulation transcriptional regulator spoiiid EKQ63_27870 ENOG4105FRN stage II sporulation protein EKQ63_27885 ENOG4105DY9 regulatoR EKQ63_27905 ENOG4106778 Protein of unknown function (DUF1146) EKQ63_27910 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) EKQ63_27915 ENOG4105C8S subunit m EKQ63_27920 ENOG4105D65 subunit l EKQ63_27950 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain EKQ63_27965 ENOG4105BZU Histidine kinase EKQ63_28015 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) EKQ63_28020 ENOG41062M3 atp synthase EKQ63_28050 ENOG4108YZG isomerase EKQ63_28065 ENOG4108VGI doxx family EKQ63_28070 ENOG4107XC4 flavin reductase domain protein, FMN-binding EKQ63_28085 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) EKQ63_28095 ENOG4108ZXQ stage ii sporulation protein r EKQ63_28100 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EKQ63_28105 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) EKQ63_28120 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) EKQ63_28125 ENOG4105CBT Fructose-1,6-bisphosphatase EKQ63_28130 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) EKQ63_28165 ENOG4105C1G acyl-Coa dehydrogenase EKQ63_28170 ENOG4105C1G acyl-Coa dehydrogenase EKQ63_28175 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase EKQ63_28185 ENOG4105DF6 Fe-S oxidoreductase EKQ63_28200 ENOG4105BZU Histidine kinase EKQ63_28230 ENOG4105BZU Histidine kinase EKQ63_28235 ENOG4105KCT ABC transporter EKQ63_28240 ENOG4108M15 ABC transporter EKQ63_28245 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) EKQ63_28250 ENOG4105IIU Aminopeptidase EKQ63_28295 ENOG4105EMN RNA polymerase sigma factor EKQ63_28305 ENOG410684U Domain of unknown function (DUF1934) EKQ63_28330 ENOG4105CYW agmatinase EKQ63_28340 ENOG4105DXB Major Facilitator superfamily EKQ63_28345 ENOG4107SWG transcriptional regulator MERR family EKQ63_28350 ENOG4108QXE glycerophosphoryl diester phosphodiesterase EKQ63_28355 ENOG4105BZ4 penicillin-binding protein EKQ63_28360 ENOG4108XFG YwhD family EKQ63_28365 ENOG4108Z4T Peptidase M50 EKQ63_28370 ENOG41069HH 4-oxalocrotonate tautomerase EKQ63_28375 ENOG4105DCI Phosphohydrolase EKQ63_28380 ENOG4108V5C ABC transporter EKQ63_28385 ENOG4105E0A ABC, transporter EKQ63_28390 ENOG4105EHG Permease protein EKQ63_28395 ENOG4105DQ5 transport system permease protein EKQ63_28405 ENOG4108VCI transcription factor, rsfa family EKQ63_28415 ENOG4108IJ2 phosphate acetyltransferase EKQ63_28430 ENOG4108VKI Cell wall hydrolase EKQ63_28450 ENOG4107SVH Potassium channel protein EKQ63_28460 ENOG410667J hydrolase EKQ63_28465 ENOG4105VCH membrane EKQ63_28475 ENOG4108TU7 Inherit from COG: (ABC) transporter EKQ63_28480 ENOG4105CJ1 ABC, transporter EKQ63_28485 ENOG41090WU lipolytic protein G-D-S-L family EKQ63_28500 ENOG4105D6E homoserine dehydrogenase EKQ63_28525 ENOG4108Y4K DNA-binding transcriptional activator EKQ63_28535 ENOG4105WH1 Two component transcriptional regulator luxr family EKQ63_28540 ENOG4105BZU Histidine kinase EKQ63_28545 ENOG4105DWF phosphomethylpyrimidine kinase EKQ63_28550 ENOG4105BZU Histidine kinase EKQ63_28555 ENOG4105VCD cytoplasmic protein EKQ63_28560 ENOG4105D22 carbon starvation protein EKQ63_28565 ENOG4105DY9 regulatoR EKQ63_28570 ENOG41079KZ Major Facilitator Superfamily EKQ63_28585 ENOG4105CG5 Glycosyl transferase (Group 1 EKQ63_28595 ENOG4105EN6 Membrane EKQ63_28600 ENOG4106YBV Methyl-accepting chemotaxis EKQ63_28610 ENOG4108S4H thioesterase Superfamily protein EKQ63_28615 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) EKQ63_28625 ENOG4105K64 Glycosyl transferase, family 2 EKQ63_28645 ENOG4105C5H ABC transporter EKQ63_28660 ENOG4105CKK Glycosyl transferase, family 2 EKQ63_28665 ENOG41067SE Tetr family transcriptional regulator EKQ63_28675 ENOG4105E0X reductase EKQ63_28680 ENOG4106F5Q Membrane EKQ63_28695 ENOG4105DY9 regulatoR EKQ63_28700 ENOG4108HRK Histidine kinase EKQ63_28705 ENOG4107RGD Major Facilitator superfamily EKQ63_28725 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EKQ63_28735 ENOG4105IW1 AmiS UreI transporter EKQ63_28770 ENOG4105CMR udp-glucose 4-epimerase EKQ63_28775 ENOG4108UT2 hemolysin iii EKQ63_28785 ENOG4105C1J atp-dependent rna helicase EKQ63_28795 ENOG4105DPN Oligoendopeptidase f EKQ63_28815 ENOG4105C0H protease EKQ63_28820 ENOG4105Q2H domain protein EKQ63_28835 ENOG4105BZU Histidine kinase EKQ63_28840 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EKQ63_28870 ENOG4105CDU Replicative dna helicase EKQ63_28880 ENOG4105BZR domain protein EKQ63_28885 ENOG4108XMW Membrane EKQ63_28895 ENOG4108UUM single-stranded DNA-binding protein EKQ63_28905 ENOG4105C3G gtp-binding protein EKQ63_28910 ENOG4105VDK protein, conserved in bacteria EKQ63_28915 ENOG4105D8X mechanosensitive ion channel EKQ63_28920 ENOG4108ZDA Sporulation protein YyaC EKQ63_28925 ENOG4105FA0 parb-like partition protein EKQ63_28930 ENOG4107QJE Chromosome Partitioning Protein EKQ63_28960 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EKQ63_28980 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EKQ63_28985 ENOG410848D S4 domain protein YaaA EKQ63_29000 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EKQ63_29045 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin EKQ63_29050 ENOG4105WH1 Two component transcriptional regulator luxr family EKQ63_29055 ENOG4108XG2 Histidine kinase EKQ63_29060 ENOG4105CAQ asparagine synthetase EKQ63_29065 ENOG4105BZU Histidine kinase EKQ63_29105 ENOG4105VZ8 Transcriptional regulator EKQ63_29120 ENOG4108VXD carboxy-peptidase EKQ63_29140 ENOG4105C19 ABC transporter EKQ63_29160 ENOG4107ZTW SNARE associated Golgi EKQ63_29170 ENOG41075H3 AraC family transcriptional regulator EKQ63_29190 ENOG4105BZU Histidine kinase EKQ63_29205 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EKQ63_29225 ENOG4108B31 Spore germination protein EKQ63_29240 ENOG4105C5Y PTS System EKQ63_29260 ENOG4108Q5U germination protein, ger(x)c family EKQ63_29270 ENOG4105F6S Spore photoproduct lyase EKQ63_29295 ENOG4105K8R UPF0145 protein EKQ63_29320 ENOG410780I phosphoprotein phosphatase activity