locus-tag	class	description
GMB29_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GMB29_00010	COG0592	DNA-directed DNA polymerase activity
GMB29_00015	COG2501	S4 domain
GMB29_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GMB29_00030	COG0187	DNA topoisomerase II activity
GMB29_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GMB29_00040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GMB29_00075	COG0516	GMP reductase activity
GMB29_00075	COG0517	IMP dehydrogenase activity
GMB29_00095	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GMB29_00100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GMB29_00110	COG1428	Deoxynucleoside kinase
GMB29_00115	COG1428	Deoxynucleoside kinase
GMB29_00120	COG3858	chitin binding
GMB29_00120	COG1388	LysM domain
GMB29_00125	COG1335	isochorismatase
GMB29_00130	COG0590	tRNA wobble adenosine to inosine editing
GMB29_00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GMB29_00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GMB29_00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GMB29_00195	COG1982	Orn Lys Arg decarboxylase major
GMB29_00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GMB29_00205	COG3870	Protein conserved in bacteria
GMB29_00210	COG1728	Protein conserved in bacteria
GMB29_00215	COG0470	DNA polymerase III
GMB29_00220	COG1774	PSP1 C-terminal conserved region
GMB29_00225	COG4467	Involved in initiation control of chromosome replication
GMB29_00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GMB29_00235	COG2827	Endonuclease containing a URI domain
GMB29_00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GMB29_00245	COG2002	toxin-antitoxin pair type II binding
GMB29_00255	COG0084	hydrolase, TatD family'
GMB29_00260	COG3584	3D domain protein
GMB29_00260	COG3583	domain protein
GMB29_00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GMB29_00280	COG4466	Protein conserved in bacteria
GMB29_00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GMB29_00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GMB29_00300	COG0251	oxidation-reduction process
GMB29_00305	COG2088	sporulation resulting in formation of a cellular spore
GMB29_00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GMB29_00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GMB29_00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GMB29_00325	COG0193	aminoacyl-tRNA hydrolase activity
GMB29_00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GMB29_00340	COG2002	toxin-antitoxin pair type II binding
GMB29_00345	COG2244	polysaccharide biosynthetic process
GMB29_00350	COG3956	TIGRFAM MazG family protein
GMB29_00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GMB29_00375	COG1098	S1 RNA binding domain
GMB29_00390	COG2208	phosphoserine phosphatase activity
GMB29_00395	COG2304	oxidoreductase activity
GMB29_00400	COG0515	serine threonine protein kinase
GMB29_00405	COG0037	tRNA processing
GMB29_00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMB29_00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GMB29_00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GMB29_00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMB29_00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GMB29_00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GMB29_00445	COG0512	Glutamine amidotransferase of anthranilate synthase
GMB29_00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GMB29_00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GMB29_00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GMB29_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GMB29_00470	COG1396	sequence-specific DNA binding
GMB29_00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GMB29_00560	COG1285	pathogenesis
GMB29_00570	COG3880	PFAM UvrB UvrC protein
GMB29_00575	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GMB29_00580	COG0542	response to heat
GMB29_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GMB29_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GMB29_00595	COG4956	integral membrane protein (PIN domain superfamily)
GMB29_00610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GMB29_00615	COG1045	serine acetyltransferase
GMB29_00620	COG0215	cysteine-tRNA ligase activity
GMB29_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GMB29_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GMB29_00635	COG3688	RNA-binding protein containing a PIN domain
GMB29_00640	COG1595	DNA-templated transcription, initiation
GMB29_00645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GMB29_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GMB29_00655	COG0250	Participates in transcription elongation, termination and antitermination
GMB29_00665	COG0081	regulation of translation
GMB29_00670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GMB29_00680	COG2813	Specifically methylates the guanine in position
GMB29_00685	COG0085	RNA polymerase activity
GMB29_00690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GMB29_00695	COG1358	cellular component organization or biogenesis
GMB29_00705	COG0049	tRNA binding
GMB29_00720	COG0051	transcription antitermination factor activity, RNA binding
GMB29_00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GMB29_00730	COG0088	Forms part of the polypeptide exit tunnel
GMB29_00735	COG0089	rRNA binding
GMB29_00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GMB29_00745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GMB29_00750	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GMB29_00755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GMB29_00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GMB29_00765	COG0255	Belongs to the universal ribosomal protein uL29 family
GMB29_00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GMB29_00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GMB29_00790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GMB29_00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GMB29_00810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GMB29_00815	COG1841	ribosomal large subunit assembly
GMB29_00820	COG0200	Binds to the 23S rRNA
GMB29_00825	COG0201	protein transport
GMB29_00830	COG0563	adenylate kinase activity
GMB29_00835	COG0024	Methionine aminopeptidase
GMB29_00840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GMB29_00845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GMB29_00850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GMB29_00860	COG0202	RNA polymerase activity
GMB29_00865	COG0203	ribosomal protein L17
GMB29_00870	COG1122	ATPase activity
GMB29_00875	COG1122	ATPase activity
GMB29_00880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GMB29_00885	COG0101	tRNA pseudouridine synthase activity
GMB29_00890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GMB29_00895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GMB29_00900	COG0582	viral genome integration into host DNA
GMB29_00910	COG1376	ErfK ybiS ycfS ynhG family protein
GMB29_00915	COG0833	amino acid
GMB29_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
GMB29_00930	COG0489	protein tyrosine kinase activity
GMB29_00940	COG2194	sulfuric ester hydrolase activity
GMB29_00945	COG0726	polysaccharide deacetylase
GMB29_01020	COG1595	DNA-templated transcription, initiation
GMB29_01025	COG5662	AntiSigma factor
GMB29_01030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GMB29_01035	COG4856	YbbR-like protein
GMB29_01040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMB29_01045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GMB29_01060	COG0583	DNA-binding transcription factor activity
GMB29_01070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_01075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GMB29_01090	COG2350	Protein conserved in bacteria
GMB29_01095	COG0179	Fumarylacetoacetate (FAA) hydrolase
GMB29_01110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GMB29_01120	COG2211	Major facilitator Superfamily
GMB29_01120	COG2190	(PTS) system
GMB29_01125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMB29_01125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMB29_01130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMB29_01130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMB29_01140	COG0697	spore germination
GMB29_01145	COG1280	lysine exporter protein (LysE YggA)
GMB29_01150	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GMB29_01160	COG3238	Protein conserved in bacteria
GMB29_01165	COG1181	Belongs to the D-alanine--D-alanine ligase family
GMB29_01170	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GMB29_01180	COG0513	Belongs to the DEAD box helicase family
GMB29_01185	COG3402	PFAM membrane-flanked domain
GMB29_01190	COG3428	Bacterial PH domain
GMB29_01195	COG0705	Rhomboid family
GMB29_01200	COG0736	holo-[acyl-carrier-protein] synthase activity
GMB29_01205	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GMB29_01210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GMB29_01215	COG0864	Transcriptional regulator
GMB29_01220	COG2337	Toxic component of a toxin-antitoxin (TA) module
GMB29_01225	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_01230	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_01235	COG2172	sigma factor antagonist activity
GMB29_01240	COG2208	phosphoserine phosphatase activity
GMB29_01245	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_01250	COG2172	sigma factor antagonist activity
GMB29_01255	COG1191	sigma factor activity
GMB29_01260	COG2208	phosphoserine phosphatase activity
GMB29_01265	COG2183	response to ionizing radiation
GMB29_01275	COG3091	SprT-like family
GMB29_01360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GMB29_01365	COG0802	atpase or kinase
GMB29_01370	COG1214	PFAM Peptidase M22, glycoprotease
GMB29_01375	COG0456	acetyltransferase
GMB29_01385	COG0488	(ABC) transporter
GMB29_01390	COG0315	cyclic pyranopterin monophosphate synthase activity
GMB29_01395	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GMB29_01400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_01405	COG0805	protein transport
GMB29_01415	COG1266	CAAX protease self-immunity
GMB29_01420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMB29_01425	COG0459	protein refolding
GMB29_01430	COG0457	Tetratricopeptide repeat
GMB29_01435	COG1063	alcohol dehydrogenase
GMB29_01440	COG2211	Major facilitator Superfamily
GMB29_01445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMB29_01455	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GMB29_01465	COG3639	organic phosphonate transmembrane transporter activity
GMB29_01495	COG2207	Transcriptional regulator
GMB29_01495	COG1609	Transcriptional regulator
GMB29_01515	COG1609	Transcriptional regulator
GMB29_01520	COG0366	Alpha amylase catalytic
GMB29_01525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_01525	COG2190	(PTS) system
GMB29_01525	COG1263	PTS System
GMB29_01540	COG0840	transmembrane signaling receptor activity
GMB29_01545	COG0714	Associated with various cellular activities
GMB29_01550	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GMB29_01555	COG1305	Transglutaminase-like
GMB29_01560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GMB29_01560	COG0519	Catalyzes the synthesis of GMP from XMP
GMB29_01565	COG2252	PERMEase
GMB29_01595	COG0463	Glycosyl transferase, family 2
GMB29_01720	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_01755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GMB29_01760	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GMB29_01765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GMB29_01775	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GMB29_01780	COG0047	phosphoribosylformylglycinamidine synthase activity
GMB29_01785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GMB29_01790	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GMB29_01795	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GMB29_01800	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GMB29_01805	COG0138	bifunctional purine biosynthesis protein purh
GMB29_01810	COG0151	Belongs to the GarS family
GMB29_01820	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GMB29_01825	COG1470	cell adhesion involved in biofilm formation
GMB29_01830	COG4496	protein, YerC YecD
GMB29_01840	COG0210	DNA helicase
GMB29_01845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GMB29_01850	COG4851	CamS sex pheromone cAM373 precursor
GMB29_01860	COG0385	Bile acid
GMB29_01865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_01875	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GMB29_01880	COG0154	amidase activity
GMB29_01890	COG0628	permease
GMB29_01895	COG1392	Phosphate transport regulator
GMB29_01900	COG0306	phosphate transporter
GMB29_01905	COG1597	lipid kinase activity
GMB29_01910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GMB29_01915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GMB29_01930	COG0438	transferase activity, transferring glycosyl groups
GMB29_01945	COG1621	beta-fructofuranosidase activity
GMB29_01950	COG1621	beta-fructofuranosidase activity
GMB29_01955	COG1653	transport
GMB29_01960	COG4753	response regulator
GMB29_01960	COG2207	Transcriptional regulator
GMB29_01965	COG2972	Histidine kinase
GMB29_01970	COG4807	Protein conserved in bacteria
GMB29_01980	COG1309	transcriptional regulator
GMB29_01990	COG1846	Transcriptional regulator
GMB29_01995	COG0386	Belongs to the glutathione peroxidase family
GMB29_02010	COG0477	Major facilitator Superfamily
GMB29_02030	COG2814	Major facilitator Superfamily
GMB29_02040	COG2322	membrane
GMB29_02050	COG1114	Component of the transport system for branched-chain amino acids
GMB29_02055	COG1733	regulation of RNA biosynthetic process
GMB29_02070	COG0626	cystathionine gamma-synthase activity
GMB29_02075	COG1115	amino acid carrier protein
GMB29_02080	COG0789	Transcriptional regulator
GMB29_02085	COG1253	flavin adenine dinucleotide binding
GMB29_02095	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GMB29_02100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GMB29_02110	COG0697	spore germination
GMB29_02125	COG1733	regulation of RNA biosynthetic process
GMB29_02130	COG2814	Major facilitator Superfamily
GMB29_02135	COG0656	L-ascorbic acid biosynthetic process
GMB29_02145	COG0166	Belongs to the GPI family
GMB29_02165	COG1129	ABC transporter
GMB29_02170	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_02175	COG0527	aspartate kinase activity
GMB29_02180	COG1609	Transcriptional regulator
GMB29_02185	COG1263	PTS System
GMB29_02185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_02190	COG1621	beta-fructofuranosidase activity
GMB29_02195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMB29_02210	COG1388	LysM domain
GMB29_02210	COG3584	3D domain protein
GMB29_02215	COG2223	nitrite transmembrane transporter activity
GMB29_02225	COG1178	ABC-type Fe3 transport system permease component
GMB29_02230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GMB29_02235	COG1132	(ABC) transporter
GMB29_02240	COG1132	(ABC) transporter
GMB29_02245	COG1115	amino acid carrier protein
GMB29_02250	COG0604	alcohol dehydrogenase
GMB29_02260	COG1131	(ABC) transporter
GMB29_02265	COG1725	Transcriptional regulator
GMB29_02280	COG0488	(ABC) transporter
GMB29_02285	COG1994	Peptidase M50
GMB29_02290	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GMB29_02310	COG1073	alpha beta
GMB29_02320	COG0693	protein deglycase activity
GMB29_02330	COG4840	Belongs to the UPF0435 family
GMB29_02335	COG1115	amino acid carrier protein
GMB29_02340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GMB29_02350	COG1295	ribonuclease BN
GMB29_02360	COG0477	Major facilitator Superfamily
GMB29_02370	COG0387	Pfam Sodium calcium exchanger
GMB29_02375	COG2364	Membrane
GMB29_02385	COG0535	radical SAM domain protein
GMB29_02410	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GMB29_02415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GMB29_02425	COG2608	mercury ion transmembrane transporter activity
GMB29_02430	COG2217	Heavy metal translocating P-type atpase
GMB29_02450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_02455	COG0659	secondary active sulfate transmembrane transporter activity
GMB29_02460	COG0288	reversible hydration of carbon dioxide
GMB29_02465	COG0745	RESPONSE REGULATOR receiver
GMB29_02470	COG5002	protein histidine kinase activity
GMB29_02485	COG3239	Fatty acid desaturase
GMB29_02490	COG2197	response regulator
GMB29_02510	COG1607	acyl-coa hydrolase
GMB29_02515	COG0583	DNA-binding transcription factor activity
GMB29_02530	COG4149	molybdate abc transporter
GMB29_02540	COG2814	Major facilitator Superfamily
GMB29_02555	COG0395	ABC-type sugar transport system, permease component
GMB29_02565	COG3842	ATPase activity
GMB29_02570	COG1349	DNA-binding transcription factor activity
GMB29_02575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GMB29_02580	COG0446	pyridine nucleotide-disulphide oxidoreductase
GMB29_02585	COG2205	protein histidine kinase activity
GMB29_02585	COG0784	Response regulator, receiver
GMB29_02590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GMB29_02595	COG5002	protein histidine kinase activity
GMB29_02605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMB29_02625	COG0673	inositol 2-dehydrogenase activity
GMB29_02635	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMB29_02640	COG0513	Belongs to the DEAD box helicase family
GMB29_02665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMB29_02670	COG1090	epimerase
GMB29_02685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GMB29_02705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GMB29_02710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GMB29_02735	COG2137	regulation of response to DNA damage stimulus
GMB29_02760	COG1988	membrane-bound metal-dependent
GMB29_02765	COG1194	a g-specific adenine glycosylase
GMB29_02775	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_02790	COG3557	Belongs to the UPF0374 family
GMB29_02795	COG1132	(ABC) transporter
GMB29_02800	COG4129	membrane
GMB29_02805	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GMB29_02810	COG4555	ABC transporter
GMB29_02830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GMB29_02835	COG0735	belongs to the Fur family
GMB29_02950	COG1609	Transcriptional regulator
GMB29_02965	COG0395	ABC-type sugar transport system, permease component
GMB29_02970	COG1621	beta-fructofuranosidase activity
GMB29_02985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_02990	COG0805	protein transport
GMB29_03005	COG1609	Transcriptional regulator
GMB29_03010	COG1879	ABC-type sugar transport system periplasmic component
GMB29_03020	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_03025	COG1621	beta-fructofuranosidase activity
GMB29_03035	COG1621	beta-fructofuranosidase activity
GMB29_03060	COG0402	S-adenosylhomocysteine deaminase activity
GMB29_03065	COG3583	domain protein
GMB29_03065	COG3584	3D domain protein
GMB29_03100	COG1070	Carbohydrate kinase
GMB29_03120	COG0561	phosphatase activity
GMB29_03325	COG4974	Belongs to the 'phage' integrase family
GMB29_03335	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_03340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMB29_03345	COG2271	Major facilitator Superfamily
GMB29_03355	COG2186	Transcriptional regulator
GMB29_03360	COG2186	Transcriptional regulator
GMB29_03365	COG2271	Major facilitator Superfamily
GMB29_03385	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_03400	COG2610	gluconate transmembrane transporter activity
GMB29_03420	COG4977	sequence-specific DNA binding
GMB29_03425	COG2259	Doxx family
GMB29_03445	COG2972	Histidine kinase
GMB29_03450	COG2207	Transcriptional regulator
GMB29_03450	COG4753	response regulator
GMB29_03460	COG3382	B3 4 domain protein
GMB29_03470	COG1970	mechanosensitive ion channel activity
GMB29_03480	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GMB29_03485	COG2766	serine protein kinase
GMB29_03495	COG1253	flavin adenine dinucleotide binding
GMB29_03500	COG2207	Transcriptional regulator
GMB29_03500	COG4753	response regulator
GMB29_03505	COG2972	Histidine kinase
GMB29_03525	COG3250	beta-galactosidase activity
GMB29_03535	COG0667	Aldo Keto reductase
GMB29_03540	COG2814	Major facilitator Superfamily
GMB29_03550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_03555	COG4605	iron ion homeostasis
GMB29_03560	COG4604	ABC transporter, ATP-binding protein
GMB29_03565	COG4607	ABC-type enterochelin transport system periplasmic component
GMB29_03570	COG0598	Magnesium transport protein CorA
GMB29_03575	COG2249	NAD(P)H dehydrogenase (quinone) activity
GMB29_03580	COG3764	Sortase (surface protein transpeptidase)
GMB29_03585	COG0805	protein transport
GMB29_03590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_03600	COG0564	pseudouridine synthase activity
GMB29_03610	COG3118	belongs to the thioredoxin family
GMB29_03620	COG0517	IMP dehydrogenase activity
GMB29_03625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GMB29_03630	COG3153	acetyltransferase
GMB29_03630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMB29_03635	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GMB29_03640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMB29_03660	COG1959	2 iron, 2 sulfur cluster binding
GMB29_03670	COG1937	Protein conserved in bacteria
GMB29_03675	COG0425	Belongs to the sulfur carrier protein TusA family
GMB29_03680	COG2210	Belongs to the sulfur carrier protein TusA family
GMB29_03695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMB29_03695	COG0425	Belongs to the sulfur carrier protein TusA family
GMB29_03700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMB29_03700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_03705	COG0730	response to heat
GMB29_03720	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GMB29_03735	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GMB29_03740	COG3639	organic phosphonate transmembrane transporter activity
GMB29_03745	COG3639	organic phosphonate transmembrane transporter activity
GMB29_03755	COG0805	protein transport
GMB29_03760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_03795	COG3627	carbon phosphorus lyase activity
GMB29_03800	COG4107	phosphonate C-P lyase system protein PhnK
GMB29_03805	COG3454	Phosphonate metabolism
GMB29_03815	COG4778	phosphonate C-P lyase system protein PhnL
GMB29_03820	COG0613	PHP domain protein
GMB29_03825	COG2719	SpoVR family
GMB29_03830	COG0860	N-Acetylmuramoyl-L-alanine amidase
GMB29_03835	COG0860	N-Acetylmuramoyl-L-alanine amidase
GMB29_03850	COG2217	Heavy metal translocating P-type atpase
GMB29_03855	COG1388	LysM domain
GMB29_03875	COG0745	RESPONSE REGULATOR receiver
GMB29_03880	COG5002	protein histidine kinase activity
GMB29_03900	COG2072	flavoprotein involved in K transport
GMB29_03905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GMB29_03910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GMB29_03915	COG1742	UPF0060 membrane protein
GMB29_03920	COG0840	transmembrane signaling receptor activity
GMB29_03925	COG0784	Response regulator, receiver
GMB29_03925	COG3437	response regulator, receiver
GMB29_03930	COG4187	Peptidase family M20/M25/M40
GMB29_03935	COG4129	membrane
GMB29_03950	COG0561	phosphatase activity
GMB29_03955	COG0673	inositol 2-dehydrogenase activity
GMB29_03960	COG0753	catalase activity
GMB29_03965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GMB29_03970	COG0586	Pfam SNARE associated Golgi protein
GMB29_03975	COG2733	membrane
GMB29_03980	COG0659	secondary active sulfate transmembrane transporter activity
GMB29_03990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GMB29_03995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GMB29_04005	COG1757	Na H antiporter
GMB29_04010	COG0589	response to stress
GMB29_04020	COG0393	Putative heavy-metal-binding
GMB29_04035	COG3842	ATPase activity
GMB29_04040	COG2508	Transcriptional regulator
GMB29_04050	COG0189	ligase activity
GMB29_04055	COG0189	ligase activity
GMB29_04060	COG0189	ligase activity
GMB29_04065	COG0189	ligase activity
GMB29_04070	COG3679	Belongs to the UPF0342 family
GMB29_04075	COG0561	phosphatase activity
GMB29_04085	COG4589	Belongs to the CDS family
GMB29_04095	COG1113	amino acid transport
GMB29_04105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMB29_04110	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_04115	COG2205	protein histidine kinase activity
GMB29_04120	COG1024	Enoyl-CoA hydratase
GMB29_04130	COG4152	abc transporter atp-binding protein
GMB29_04135	COG1668	transmembrane transport
GMB29_04150	COG0420	3'-5' exonuclease activity
GMB29_04155	COG4717	serine-type aminopeptidase activity
GMB29_04160	COG3481	metal-dependent phosphohydrolase, HD sub domain
GMB29_04170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMB29_04200	COG1846	Transcriptional regulator
GMB29_04220	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GMB29_04225	COG0537	adenosine 5'-monophosphoramidase activity
GMB29_04230	COG1131	(ABC) transporter
GMB29_04235	COG4473	ABC transporter
GMB29_04245	COG1473	amidohydrolase
GMB29_04250	COG0671	phosphoesterase, PA-phosphatase related
GMB29_04260	COG1131	(ABC) transporter
GMB29_04275	COG2271	Major facilitator Superfamily
GMB29_04280	COG0405	Gamma-glutamyltransferase
GMB29_04285	COG1522	sequence-specific DNA binding
GMB29_04290	COG2059	Chromate
GMB29_04295	COG2059	Chromate
GMB29_04300	COG3069	C4-dicarboxylate transmembrane transporter activity
GMB29_04305	COG2329	Antibiotic biosynthesis monooxygenase
GMB29_04310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GMB29_04315	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GMB29_04340	COG1070	Carbohydrate kinase
GMB29_04345	COG2610	gluconate transmembrane transporter activity
GMB29_04350	COG1737	Transcriptional regulator
GMB29_04360	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GMB29_04380	COG1309	transcriptional regulator
GMB29_04385	COG1511	domain protein
GMB29_04395	COG4895	conserved protein (DUF2196)
GMB29_04405	COG1609	Transcriptional regulator
GMB29_04415	COG1234	tRNA 3'-trailer cleavage
GMB29_04420	COG0095	Lipoate-protein ligase
GMB29_04425	COG1279	arginine transmembrane transporter activity
GMB29_04445	COG0318	PFAM AMP-dependent synthetase and ligase
GMB29_04455	COG4120	Belongs to the binding-protein-dependent transport system permease family
GMB29_04460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GMB29_04460	COG1116	anion transmembrane transporter activity
GMB29_04475	COG0363	glucosamine-6-phosphate deaminase activity
GMB29_04480	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GMB29_04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_04485	COG1263	PTS System
GMB29_04495	COG4821	SIS domain
GMB29_04500	COG1396	sequence-specific DNA binding
GMB29_04505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GMB29_04515	COG0501	Belongs to the peptidase M48B family
GMB29_04520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GMB29_04525	COG2224	Isocitrate lyase
GMB29_04530	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GMB29_04540	COG4903	ComK protein
GMB29_04550	COG0398	Pfam SNARE associated Golgi protein
GMB29_04560	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GMB29_04565	COG1074	ATP-dependent DNA helicase activity
GMB29_04570	COG0420	3'-5' exonuclease activity
GMB29_04575	COG0419	ATPase involved in DNA repair
GMB29_04615	COG0084	hydrolase, TatD family'
GMB29_04620	COG0179	Fumarylacetoacetate (FAA) hydrolase
GMB29_04630	COG3290	protein histidine kinase activity
GMB29_04635	COG4565	transcriptional regulatory protein
GMB29_04640	COG3181	Tripartite tricarboxylate transporter family receptor
GMB29_04650	COG2851	Citrate transporter
GMB29_04660	COG0367	asparagine synthase
GMB29_04665	COG0784	Response regulator, receiver
GMB29_04670	COG4191	Histidine kinase
GMB29_04680	COG1027	Aspartate ammonia-lyase
GMB29_04690	COG1917	Cupin 2, conserved barrel domain protein
GMB29_04690	COG2207	Transcriptional regulator
GMB29_04700	COG1874	Beta-galactosidase
GMB29_04700	COG0366	Alpha amylase catalytic
GMB29_04710	COG2801	Transposase and inactivated derivatives
GMB29_04715	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_04720	COG0646	methionine synthase
GMB29_04720	COG1410	methionine synthase
GMB29_04725	COG0646	methionine synthase
GMB29_04725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GMB29_04730	COG1666	GTP binding
GMB29_04735	COG2996	Protein conserved in bacteria
GMB29_04745	COG0840	transmembrane signaling receptor activity
GMB29_04755	COG1307	EDD domain protein, DegV family
GMB29_04760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GMB29_04775	COG0561	phosphatase activity
GMB29_04780	COG1073	alpha beta
GMB29_04785	COG2151	metal-sulfur cluster biosynthetic enzyme
GMB29_04790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GMB29_04795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GMB29_04810	COG0505	Belongs to the CarA family
GMB29_04815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GMB29_04820	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GMB29_04835	COG2267	carboxylic ester hydrolase activity
GMB29_04845	COG1744	ABC transporter substrate-binding protein PnrA-like
GMB29_04860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMB29_04865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMB29_04870	COG5504	Zn-dependent protease
GMB29_04880	COG0180	Tryptophanyl-tRNA synthetase
GMB29_04890	COG4166	transmembrane transport
GMB29_04895	COG0601	transmembrane transport
GMB29_04900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GMB29_04905	COG0444	Belongs to the ABC transporter superfamily
GMB29_04910	COG4608	Belongs to the ABC transporter superfamily
GMB29_04915	COG0456	acetyltransferase
GMB29_04920	COG1393	Belongs to the ArsC family
GMB29_04925	COG0861	Integral membrane protein TerC family
GMB29_04930	COG4862	establishment of competence for transformation
GMB29_04935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMB29_04940	COG4469	Competence protein
GMB29_04950	COG1164	Oligoendopeptidase f
GMB29_04975	COG2346	COG2346, Truncated hemoglobins
GMB29_04980	COG0741	lytic transglycosylase activity
GMB29_04985	COG4116	CYTH
GMB29_04995	COG2357	RelA SpoT domain protein
GMB29_05000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GMB29_05005	COG0564	pseudouridine synthase activity
GMB29_05010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GMB29_05015	COG0772	Belongs to the SEDS family
GMB29_05020	COG2239	Acts as a magnesium transporter
GMB29_05025	COG0475	glutathione-regulated potassium exporter activity
GMB29_05025	COG0569	domain protein
GMB29_05030	COG0352	thiamine-phosphate diphosphorylase activity
GMB29_05035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMB29_05040	COG2104	thiamine diphosphate biosynthetic process
GMB29_05045	COG2022	thiamine diphosphate biosynthetic process
GMB29_05050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GMB29_05065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GMB29_05070	COG2200	EAL domain
GMB29_05115	COG0653	protein targeting
GMB29_05145	COG4641	Protein conserved in bacteria
GMB29_05175	COG4641	Protein conserved in bacteria
GMB29_05220	COG0438	transferase activity, transferring glycosyl groups
GMB29_05220	COG1216	Glycosyl transferase, family 2
GMB29_05240	COG1086	Polysaccharide biosynthesis protein
GMB29_05255	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GMB29_05260	COG1091	dTDP-4-dehydrorhamnose reductase activity
GMB29_05265	COG1088	dTDP-glucose 4,6-dehydratase activity
GMB29_05270	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GMB29_05275	COG0210	DNA helicase
GMB29_05285	COG2323	membrane
GMB29_05290	COG2153	protein acetylation
GMB29_05295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GMB29_05300	COG2382	esterase
GMB29_05310	COG0626	cystathionine gamma-synthase activity
GMB29_05315	COG0626	cystathionine gamma-synthase activity
GMB29_05325	COG2153	protein acetylation
GMB29_05350	COG4974	Belongs to the 'phage' integrase family
GMB29_05395	COG0662	Cupin 2, conserved barrel domain protein
GMB29_05400	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GMB29_05445	COG0569	domain protein
GMB29_05450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GMB29_05480	COG2205	protein histidine kinase activity
GMB29_05520	COG2801	Transposase and inactivated derivatives
GMB29_05545	COG4753	response regulator
GMB29_05545	COG2207	Transcriptional regulator
GMB29_05550	COG2972	Histidine kinase
GMB29_05560	COG1879	ABC-type sugar transport system periplasmic component
GMB29_05570	COG1879	ABC-type sugar transport system periplasmic component
GMB29_05580	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_05585	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_05600	COG1904	glucuronate isomerase
GMB29_05605	COG1714	RDD family
GMB29_05610	COG5002	protein histidine kinase activity
GMB29_05615	COG0745	RESPONSE REGULATOR receiver
GMB29_05620	COG0666	response to abiotic stimulus
GMB29_05635	COG1486	melibiose metabolic process
GMB29_05640	COG0583	DNA-binding transcription factor activity
GMB29_05650	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMB29_05655	COG1607	acyl-coa hydrolase
GMB29_05660	COG0281	malic enzyme
GMB29_05665	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_05670	COG0531	amino acid
GMB29_05675	COG0686	Belongs to the AlaDH PNT family
GMB29_05720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_05730	COG0583	DNA-binding transcription factor activity
GMB29_05735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMB29_05755	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_05765	COG0196	riboflavin kinase activity
GMB29_05770	COG2814	Major facilitator Superfamily
GMB29_05800	COG1733	regulation of RNA biosynthetic process
GMB29_05815	COG1917	Cupin 2, conserved barrel domain protein
GMB29_05815	COG4977	sequence-specific DNA binding
GMB29_05820	COG0586	Pfam SNARE associated Golgi protein
GMB29_05835	COG0196	riboflavin kinase activity
GMB29_05840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GMB29_05845	COG2814	Major facilitator Superfamily
GMB29_05850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GMB29_05855	COG0196	riboflavin kinase activity
GMB29_05865	COG2188	Transcriptional regulator
GMB29_05875	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GMB29_05885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GMB29_05915	COG4873	Protein conserved in bacteria
GMB29_05920	COG1609	Transcriptional regulator
GMB29_05925	COG0366	Alpha amylase catalytic
GMB29_05930	COG1263	PTS System
GMB29_05930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_05980	COG0668	transmembrane transport
GMB29_06005	COG1794	racemase activity, acting on amino acids and derivatives
GMB29_06020	COG2814	Major facilitator Superfamily
GMB29_06025	COG1473	amidohydrolase
GMB29_06030	COG1113	amino acid transport
GMB29_06040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GMB29_06045	COG1760	l-serine dehydratase
GMB29_06050	COG1760	l-serine dehydratase
GMB29_06060	COG0509	glycine decarboxylation via glycine cleavage system
GMB29_06070	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMB29_06075	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GMB29_06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMB29_06095	COG0788	formyltetrahydrofolate deformylase activity
GMB29_06105	COG1764	response to oxidative stress
GMB29_06110	COG3949	Membrane
GMB29_06115	COG1609	Transcriptional regulator
GMB29_06120	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GMB29_06125	COG0574	Belongs to the PEP-utilizing enzyme family
GMB29_06125	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GMB29_06130	COG1349	DNA-binding transcription factor activity
GMB29_06140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_06145	COG0805	protein transport
GMB29_06150	COG2207	Transcriptional regulator
GMB29_06155	COG3250	beta-galactosidase activity
GMB29_06160	COG2211	Major facilitator Superfamily
GMB29_06165	COG4191	Histidine kinase
GMB29_06170	COG1879	ABC-type sugar transport system periplasmic component
GMB29_06175	COG2972	Histidine kinase
GMB29_06180	COG2207	Transcriptional regulator
GMB29_06180	COG4753	response regulator
GMB29_06185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GMB29_06190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMB29_06195	COG1129	ABC transporter
GMB29_06200	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_06205	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_06210	COG1879	ABC-type sugar transport system periplasmic component
GMB29_06240	COG2207	Transcriptional regulator
GMB29_06250	COG2851	Citrate transporter
GMB29_06265	COG0179	Fumarylacetoacetate (FAA) hydrolase
GMB29_06275	COG3711	transcriptional antiterminator
GMB29_06295	COG0191	fructose-bisphosphate aldolase activity
GMB29_06340	COG0583	DNA-binding transcription factor activity
GMB29_06345	COG2814	Major facilitator Superfamily
GMB29_06350	COG1647	Serine aminopeptidase, S33
GMB29_06360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GMB29_06365	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GMB29_06370	COG1414	Transcriptional regulator
GMB29_06395	COG5577	PFAM Coat F domain
GMB29_06400	COG1063	alcohol dehydrogenase
GMB29_06410	COG1879	ABC-type sugar transport system periplasmic component
GMB29_06415	COG0318	PFAM AMP-dependent synthetase and ligase
GMB29_06425	COG1116	anion transmembrane transporter activity
GMB29_06430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GMB29_06440	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_06445	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GMB29_06450	COG0351	phosphomethylpyrimidine kinase
GMB29_06460	COG5522	Integral membrane protein (intg_mem_TP0381)
GMB29_06465	COG2972	Histidine kinase
GMB29_06470	COG4753	response regulator
GMB29_06470	COG2207	Transcriptional regulator
GMB29_06475	COG1653	transport
GMB29_06510	COG1063	alcohol dehydrogenase
GMB29_06515	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_06520	COG1263	PTS System
GMB29_06520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_06520	COG2190	(PTS) system
GMB29_06525	COG1609	Transcriptional regulator
GMB29_06525	COG2207	Transcriptional regulator
GMB29_06530	COG3250	beta-galactosidase activity
GMB29_06540	COG0582	viral genome integration into host DNA
GMB29_06550	COG2723	6-phospho-beta-galactosidase activity
GMB29_06555	COG2610	gluconate transmembrane transporter activity
GMB29_06570	COG5578	integral membrane protein
GMB29_06590	COG2972	Histidine kinase
GMB29_06595	COG4753	response regulator
GMB29_06595	COG2207	Transcriptional regulator
GMB29_06605	COG4989	oxidoreductase activity
GMB29_06615	COG4294	response to UV
GMB29_06620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GMB29_06630	COG1533	DNA photolyase activity
GMB29_06650	COG1294	oxidase, subunit
GMB29_06655	COG1271	oxidase subunit
GMB29_06670	COG3871	stress protein (general stress protein 26)
GMB29_06705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GMB29_06720	COG0109	protoheme IX farnesyltransferase activity
GMB29_06725	COG1612	heme a metabolic process
GMB29_06735	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GMB29_06745	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GMB29_06755	COG0366	Alpha amylase catalytic
GMB29_06765	COG0492	ferredoxin-NADP+ reductase activity
GMB29_06770	COG1141	Ferredoxin
GMB29_06775	COG4638	Rieske (2fe-2S)
GMB29_06780	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_06785	COG0473	3-isopropylmalate dehydrogenase activity
GMB29_06795	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_06810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_06815	COG1309	transcriptional regulator
GMB29_06825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GMB29_06840	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GMB29_06860	COG0754	glutathionylspermidine amidase activity
GMB29_06880	COG3480	Lon protease (S16) C-terminal proteolytic domain
GMB29_06905	COG1609	Transcriptional regulator
GMB29_06920	COG1175	transmembrane transport
GMB29_06930	COG0673	inositol 2-dehydrogenase activity
GMB29_06940	COG5002	protein histidine kinase activity
GMB29_06950	COG1606	tRNA processing
GMB29_06965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GMB29_06975	COG0456	acetyltransferase
GMB29_06980	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GMB29_06990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GMB29_07005	COG4974	Belongs to the 'phage' integrase family
GMB29_07070	COG1492	cobalamin metabolic process
GMB29_07080	COG0778	Nitroreductase
GMB29_07085	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GMB29_07095	COG0778	Nitroreductase
GMB29_07100	COG0310	cobalt ion transport
GMB29_07125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GMB29_07130	COG2801	Transposase and inactivated derivatives
GMB29_07140	COG0737	Belongs to the 5'-nucleotidase family
GMB29_07145	COG0346	lactoylglutathione lyase activity
GMB29_07180	COG3852	Histidine kinase
GMB29_07200	COG1653	transport
GMB29_07205	COG1175	transmembrane transport
GMB29_07210	COG0395	ABC-type sugar transport system, permease component
GMB29_07230	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_07235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_07245	COG1959	2 iron, 2 sulfur cluster binding
GMB29_07250	COG2910	NAD(P)H-binding
GMB29_07260	COG1309	transcriptional regulator
GMB29_07265	COG2508	Transcriptional regulator
GMB29_07280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GMB29_07285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GMB29_07290	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GMB29_07300	COG0561	phosphatase activity
GMB29_07310	COG1473	amidohydrolase
GMB29_07315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GMB29_07330	COG0673	inositol 2-dehydrogenase activity
GMB29_07345	COG1940	carbohydrate kinase activity
GMB29_07350	COG1904	glucuronate isomerase
GMB29_07360	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_07365	COG1606	tRNA processing
GMB29_07375	COG1691	(AIR) carboxylase
GMB29_07380	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GMB29_07395	COG0864	Transcriptional regulator
GMB29_07405	COG0601	transmembrane transport
GMB29_07410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GMB29_07415	COG0444	Belongs to the ABC transporter superfamily
GMB29_07420	COG1124	(ABC) transporter
GMB29_07430	COG0217	transcriptional regulatory protein
GMB29_07455	COG0454	-acetyltransferase
GMB29_07470	COG2318	DinB family
GMB29_07475	COG0697	spore germination
GMB29_07500	COG3290	protein histidine kinase activity
GMB29_07505	COG4565	transcriptional regulatory protein
GMB29_07510	COG3493	citrate carrier protein
GMB29_07515	COG0281	malic enzyme
GMB29_07525	COG1280	lysine exporter protein (LysE YggA)
GMB29_07530	COG1378	Sugar-specific transcriptional regulator TrmB
GMB29_07540	COG1683	Conserved Protein
GMB29_07550	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_07555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GMB29_07560	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GMB29_07570	COG3290	protein histidine kinase activity
GMB29_07570	COG3829	transcription factor binding
GMB29_07575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GMB29_07580	COG0022	dehydrogenase e1 component
GMB29_07585	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMB29_07590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMB29_07595	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_07600	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_07605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GMB29_07610	COG2226	methyltransferase
GMB29_07625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GMB29_07630	COG1846	Transcriptional regulator
GMB29_07635	COG2259	Doxx family
GMB29_07645	COG0346	lactoylglutathione lyase activity
GMB29_07650	COG0346	lactoylglutathione lyase activity
GMB29_07655	COG0400	carboxylic ester hydrolase activity
GMB29_07660	COG0655	NAD(P)H dehydrogenase (quinone) activity
GMB29_07675	COG0791	NLP P60 protein
GMB29_07675	COG1388	LysM domain
GMB29_07720	COG3153	acetyltransferase
GMB29_07735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMB29_07750	COG3829	transcription factor binding
GMB29_07750	COG3290	protein histidine kinase activity
GMB29_07760	COG0531	amino acid
GMB29_07775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GMB29_07800	COG0531	amino acid
GMB29_07810	COG0598	Magnesium transport protein CorA
GMB29_07820	COG2261	transglycosylase associated protein
GMB29_07830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GMB29_07835	COG0860	N-Acetylmuramoyl-L-alanine amidase
GMB29_07840	COG1113	amino acid transport
GMB29_07855	COG1119	ATPase activity
GMB29_07860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GMB29_07865	COG1609	Transcriptional regulator
GMB29_07890	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GMB29_07900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GMB29_07905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GMB29_07910	COG1940	carbohydrate kinase activity
GMB29_07920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMB29_07930	COG1115	amino acid carrier protein
GMB29_07935	COG0383	alpha-mannosidase activity
GMB29_07940	COG1113	amino acid transport
GMB29_07945	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GMB29_07945	COG2508	Transcriptional regulator
GMB29_07950	COG0686	Belongs to the AlaDH PNT family
GMB29_07955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GMB29_07970	COG4191	Histidine kinase
GMB29_07975	COG0784	Response regulator, receiver
GMB29_07980	COG0252	asparaginase activity
GMB29_07985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GMB29_07995	COG4145	pantothenate transmembrane transporter activity
GMB29_08000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GMB29_08005	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_08010	COG2211	Major facilitator Superfamily
GMB29_08025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GMB29_08030	COG2972	Histidine kinase
GMB29_08035	COG2207	Transcriptional regulator
GMB29_08035	COG4753	response regulator
GMB29_08050	COG1414	Transcriptional regulator
GMB29_08065	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_08070	COG0028	Belongs to the TPP enzyme family
GMB29_08080	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
GMB29_08085	COG4638	Rieske (2fe-2S)
GMB29_08095	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_08110	COG1141	Ferredoxin
GMB29_08115	COG0492	ferredoxin-NADP+ reductase activity
GMB29_08125	COG2172	sigma factor antagonist activity
GMB29_08130	COG4191	Histidine kinase
GMB29_08145	COG1609	Transcriptional regulator
GMB29_08160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMB29_08165	COG2814	Major facilitator Superfamily
GMB29_08170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GMB29_08175	COG0697	spore germination
GMB29_08180	COG0531	amino acid
GMB29_08195	COG0737	Belongs to the 5'-nucleotidase family
GMB29_08195	COG4085	toxin activity
GMB29_08195	COG1525	nuclease
GMB29_08200	COG3829	transcription factor binding
GMB29_08205	COG0456	acetyltransferase
GMB29_08210	COG1309	transcriptional regulator
GMB29_08215	COG0477	Major facilitator Superfamily
GMB29_08225	COG1509	lysine 2,3-aminomutase activity
GMB29_08235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GMB29_08240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GMB29_08245	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GMB29_08250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GMB29_08275	COG5444	nuclease activity
GMB29_08280	COG1959	2 iron, 2 sulfur cluster binding
GMB29_08285	COG5553	Cysteine dioxygenase type I
GMB29_08290	COG2368	4-hydroxyphenylacetate
GMB29_08300	COG1494	fructose-1,6-bisphosphatase
GMB29_08305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GMB29_08310	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GMB29_08315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GMB29_08320	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GMB29_08345	COG0346	lactoylglutathione lyase activity
GMB29_08355	COG0431	NADPH-dependent FMN reductase
GMB29_08360	COG4841	protein insertion into membrane
GMB29_08370	COG1733	regulation of RNA biosynthetic process
GMB29_08375	COG2259	Doxx family
GMB29_08385	COG1393	Belongs to the ArsC family
GMB29_08395	COG0346	lactoylglutathione lyase activity
GMB29_08400	COG0346	lactoylglutathione lyase activity
GMB29_08405	COG0400	carboxylic ester hydrolase activity
GMB29_08410	COG2814	Major facilitator Superfamily
GMB29_08425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMB29_08435	COG1609	Transcriptional regulator
GMB29_08445	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GMB29_08450	COG0800	Aldolase
GMB29_08465	COG1609	Transcriptional regulator
GMB29_08475	COG0598	Magnesium transport protein CorA
GMB29_08495	COG3706	GGDEF domain
GMB29_08520	COG3162	membrane
GMB29_08525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_08550	COG1757	Na H antiporter
GMB29_08580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GMB29_08600	COG3655	Transcriptional regulator
GMB29_08605	COG3739	integral membrane protein
GMB29_08620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GMB29_08625	COG1522	sequence-specific DNA binding
GMB29_08635	COG0492	ferredoxin-NADP+ reductase activity
GMB29_08655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GMB29_08680	COG1335	isochorismatase
GMB29_08690	COG1522	sequence-specific DNA binding
GMB29_08715	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_08720	COG0583	DNA-binding transcription factor activity
GMB29_08725	COG0730	response to heat
GMB29_08730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GMB29_08735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GMB29_08740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GMB29_08755	COG1609	Transcriptional regulator
GMB29_08770	COG0583	DNA-binding transcription factor activity
GMB29_08775	COG2807	transmembrane transport
GMB29_08780	COG2357	RelA SpoT domain protein
GMB29_08795	COG2814	Major facilitator Superfamily
GMB29_08800	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GMB29_08810	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GMB29_08815	COG0840	transmembrane signaling receptor activity
GMB29_08840	COG1388	LysM domain
GMB29_08840	COG0791	NLP P60 protein
GMB29_08860	COG2814	Major facilitator Superfamily
GMB29_08870	COG1309	transcriptional regulator
GMB29_08880	COG2207	Transcriptional regulator
GMB29_08890	COG0667	Aldo Keto reductase
GMB29_08905	COG1175	transmembrane transport
GMB29_08915	COG2972	Histidine kinase
GMB29_08920	COG2207	Transcriptional regulator
GMB29_08920	COG4753	response regulator
GMB29_08925	COG0596	Alpha beta hydrolase
GMB29_08930	COG1278	Cold shock
GMB29_08940	COG3959	Transketolase, thiamine diphosphate binding domain
GMB29_08945	COG3958	Transketolase
GMB29_08950	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_08955	COG2186	Transcriptional regulator
GMB29_08970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GMB29_08975	COG0698	ribose 5-phosphate isomerase
GMB29_08980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMB29_08985	COG0583	DNA-binding transcription factor activity
GMB29_08995	COG1846	Transcriptional regulator
GMB29_09000	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GMB29_09030	COG2364	Membrane
GMB29_09035	COG2153	protein acetylation
GMB29_09040	COG1846	Transcriptional regulator
GMB29_09045	COG4191	Histidine kinase
GMB29_09050	COG0784	Response regulator, receiver
GMB29_09080	COG1575	Belongs to the MenA family. Type 1 subfamily
GMB29_09100	COG2508	Transcriptional regulator
GMB29_09105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GMB29_09110	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GMB29_09115	COG2233	PERMEase
GMB29_09120	COG0154	amidase activity
GMB29_09130	COG1288	antiporter activity
GMB29_09135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMB29_09140	COG2351	hydroxyisourate hydrolase activity
GMB29_09145	COG2072	flavoprotein involved in K transport
GMB29_09155	COG2233	PERMEase
GMB29_09180	COG0579	oxidoreductase
GMB29_09215	COG3409	Peptidoglycan-binding domain 1 protein
GMB29_09215	COG3773	Cell wall hydrolase
GMB29_09220	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
GMB29_09225	COG1414	Transcriptional regulator
GMB29_09230	COG4978	Transcriptional regulator
GMB29_09230	COG0789	Transcriptional regulator
GMB29_09235	COG2814	Major facilitator Superfamily
GMB29_09255	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_09265	COG1349	DNA-binding transcription factor activity
GMB29_09280	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_09285	COG1621	beta-fructofuranosidase activity
GMB29_09290	COG1917	Cupin 2, conserved barrel domain protein
GMB29_09290	COG2207	Transcriptional regulator
GMB29_09295	COG0697	spore germination
GMB29_09320	COG4336	lyase activity
GMB29_09325	COG1914	H( )-stimulated, divalent metal cation uptake system
GMB29_09330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GMB29_09335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GMB29_09340	COG1984	allophanate hydrolase subunit 2
GMB29_09345	COG0511	ligase activity, forming carbon-carbon bonds
GMB29_09350	COG0439	Biotin carboxylase
GMB29_09410	COG1263	PTS System
GMB29_09410	COG2190	(PTS) system
GMB29_09410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_09415	COG2723	6-phospho-beta-galactosidase activity
GMB29_09420	COG2723	6-phospho-beta-galactosidase activity
GMB29_09425	COG3711	transcriptional antiterminator
GMB29_09435	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_09495	COG2072	flavoprotein involved in K transport
GMB29_09515	COG3852	Histidine kinase
GMB29_09520	COG2204	response regulator
GMB29_09540	COG1176	ABC-type spermidine putrescine transport system, permease component I
GMB29_09560	COG0277	FAD linked oxidase domain protein
GMB29_09565	COG0247	lactate metabolic process
GMB29_09570	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_09585	COG1349	DNA-binding transcription factor activity
GMB29_09640	COG2972	Histidine kinase
GMB29_09645	COG4753	response regulator
GMB29_09645	COG2207	Transcriptional regulator
GMB29_09655	COG1175	transmembrane transport
GMB29_09675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GMB29_09685	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GMB29_09690	COG3052	prosthetic group binding
GMB29_09705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GMB29_09755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GMB29_09755	COG1605	Chorismate mutase
GMB29_09795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_09800	COG0805	protein transport
GMB29_09825	COG0745	RESPONSE REGULATOR receiver
GMB29_09830	COG2205	protein histidine kinase activity
GMB29_09850	COG0730	response to heat
GMB29_09870	COG4948	Mandelate Racemase Muconate Lactonizing
GMB29_09880	COG3338	carbonate dehydratase activity
GMB29_09885	COG0288	reversible hydration of carbon dioxide
GMB29_09910	COG0659	secondary active sulfate transmembrane transporter activity
GMB29_09920	COG2824	Alkylphosphonate utilization operon protein PhnA
GMB29_09930	COG0456	acetyltransferase
GMB29_09935	COG0702	epimerase
GMB29_09955	COG0067	glutamate synthase
GMB29_09955	COG0069	glutamate synthase activity
GMB29_09955	COG0070	glutamate synthase
GMB29_09960	COG0493	'glutamate synthase
GMB29_09975	COG1834	amidinotransferase
GMB29_09990	COG5577	PFAM Coat F domain
GMB29_10005	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GMB29_10015	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GMB29_10020	COG3608	succinylglutamate desuccinylase aspartoacylase
GMB29_10020	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GMB29_10035	COG1473	amidohydrolase
GMB29_10040	COG3773	Cell wall hydrolase
GMB29_10045	COG2755	lipolytic protein G-D-S-L family
GMB29_10060	COG0318	PFAM AMP-dependent synthetase and ligase
GMB29_10075	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_10080	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_10085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GMB29_10095	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GMB29_10100	COG0277	FAD linked oxidase domain protein
GMB29_10105	COG0247	lactate metabolic process
GMB29_10110	COG0583	DNA-binding transcription factor activity
GMB29_10115	COG0697	spore germination
GMB29_10125	COG2860	membrane
GMB29_10130	COG5609	conserved protein (DUF2294)
GMB29_10175	COG0640	Transcriptional regulator
GMB29_10180	COG2323	membrane
GMB29_10185	COG1073	alpha beta
GMB29_10195	COG2204	response regulator
GMB29_10200	COG4638	Rieske (2fe-2S)
GMB29_10205	COG0028	Belongs to the TPP enzyme family
GMB29_10215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMB29_10220	COG0833	amino acid
GMB29_10230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMB29_10260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GMB29_10280	COG3773	Cell wall hydrolase
GMB29_10290	COG5444	nuclease activity
GMB29_10305	COG2814	Major facilitator Superfamily
GMB29_10320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_10325	COG0805	protein transport
GMB29_10330	COG0805	protein transport
GMB29_10335	COG1349	DNA-binding transcription factor activity
GMB29_10345	COG1263	PTS System
GMB29_10345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_10355	COG3540	Alkaline phosphatase
GMB29_10360	COG0789	Transcriptional regulator
GMB29_10365	COG1064	alcohol dehydrogenase
GMB29_10390	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_10395	COG3829	transcription factor binding
GMB29_10395	COG3290	protein histidine kinase activity
GMB29_10400	COG1024	Enoyl-CoA hydratase
GMB29_10430	COG1024	Enoyl-CoA hydratase
GMB29_10435	COG1960	acyl-CoA dehydrogenase activity
GMB29_10440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GMB29_10440	COG0045	succinate-CoA ligase (ADP-forming) activity
GMB29_10440	COG1042	CoA-binding domain protein
GMB29_10445	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMB29_10450	COG0183	Belongs to the thiolase family
GMB29_10455	COG2086	electron transfer activity
GMB29_10460	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GMB29_10465	COG0247	lactate metabolic process
GMB29_10465	COG2181	nitrate reductase activity
GMB29_10475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GMB29_10480	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GMB29_10485	COG0251	oxidation-reduction process
GMB29_10490	COG1113	amino acid transport
GMB29_10500	COG2814	Major facilitator Superfamily
GMB29_10505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GMB29_10525	COG2801	Transposase and inactivated derivatives
GMB29_10545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMB29_10555	COG1879	ABC-type sugar transport system periplasmic component
GMB29_10560	COG0156	8-amino-7-oxononanoate synthase activity
GMB29_10565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMB29_10570	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GMB29_10575	COG1335	isochorismatase
GMB29_10590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GMB29_10595	COG1024	Enoyl-CoA hydratase
GMB29_10600	COG1024	Enoyl-CoA hydratase
GMB29_10605	COG1024	Enoyl-CoA hydratase
GMB29_10610	COG0183	Belongs to the thiolase family
GMB29_10615	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMB29_10620	COG2851	Citrate transporter
GMB29_10625	COG1414	Transcriptional regulator
GMB29_10640	COG1176	ABC-type spermidine putrescine transport system, permease component I
GMB29_10645	COG1177	transmembrane transport
GMB29_10655	COG1879	ABC-type sugar transport system periplasmic component
GMB29_10670	COG3493	citrate carrier protein
GMB29_10685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GMB29_10690	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GMB29_10700	COG0579	oxidoreductase
GMB29_10705	COG0281	malic enzyme
GMB29_10710	COG3290	protein histidine kinase activity
GMB29_10715	COG4565	transcriptional regulatory protein
GMB29_10720	COG1879	ABC-type sugar transport system periplasmic component
GMB29_10725	COG1733	regulation of RNA biosynthetic process
GMB29_10745	COG0656	L-ascorbic acid biosynthetic process
GMB29_10750	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_10760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GMB29_10765	COG0583	DNA-binding transcription factor activity
GMB29_10775	COG0305	Participates in initiation and elongation during chromosome replication
GMB29_10785	COG1609	Transcriptional regulator
GMB29_10795	COG1349	DNA-binding transcription factor activity
GMB29_10800	COG0805	protein transport
GMB29_10805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_10810	COG0402	S-adenosylhomocysteine deaminase activity
GMB29_10820	COG0747	negative chemotaxis
GMB29_10830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GMB29_10835	COG0444	Belongs to the ABC transporter superfamily
GMB29_10845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GMB29_10865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GMB29_10880	COG2814	Major facilitator Superfamily
GMB29_10905	COG2217	Heavy metal translocating P-type atpase
GMB29_10935	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_10940	COG0305	Participates in initiation and elongation during chromosome replication
GMB29_10945	COG0305	Participates in initiation and elongation during chromosome replication
GMB29_10950	COG3284	Transcriptional regulator
GMB29_10955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMB29_10960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GMB29_10965	COG0022	dehydrogenase e1 component
GMB29_10970	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMB29_10980	COG0488	(ABC) transporter
GMB29_10990	COG2814	Major facilitator Superfamily
GMB29_11005	COG1175	transmembrane transport
GMB29_11010	COG0395	ABC-type sugar transport system, permease component
GMB29_11015	COG1621	beta-fructofuranosidase activity
GMB29_11035	COG2132	Multicopper oxidase
GMB29_11050	COG4264	IucA IucC family
GMB29_11055	COG4264	IucA IucC family
GMB29_11060	COG2814	Major facilitator Superfamily
GMB29_11065	COG0019	diaminopimelate decarboxylase activity
GMB29_11105	COG1879	ABC-type sugar transport system periplasmic component
GMB29_11110	COG0822	iron-sulfur transferase activity
GMB29_11115	COG0523	cobalamin synthesis protein
GMB29_11125	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GMB29_11135	COG0523	cobalamin synthesis protein
GMB29_11140	COG0803	Belongs to the bacterial solute-binding protein 9 family
GMB29_11145	COG1121	(ABC) transporter
GMB29_11150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMB29_11160	COG0521	Mo-molybdopterin cofactor biosynthetic process
GMB29_11165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GMB29_11175	COG0254	rRNA binding
GMB29_11180	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GMB29_11195	COG2318	DinB family
GMB29_11205	COG0165	Argininosuccinate lyase
GMB29_11210	COG0833	amino acid
GMB29_11220	COG2814	Major facilitator Superfamily
GMB29_11230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_11255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GMB29_11265	COG0656	L-ascorbic acid biosynthetic process
GMB29_11270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GMB29_11275	COG2814	Major facilitator Superfamily
GMB29_11290	COG2315	Protein conserved in bacteria
GMB29_11310	COG0456	acetyltransferase
GMB29_11310	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GMB29_11330	COG1309	transcriptional regulator
GMB29_11405	COG1733	regulation of RNA biosynthetic process
GMB29_11410	COG2249	NAD(P)H dehydrogenase (quinone) activity
GMB29_11425	COG0697	spore germination
GMB29_11430	COG0531	amino acid
GMB29_11440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GMB29_11445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_11450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_11500	COG0384	phenazine biosynthesis protein PhzF
GMB29_11505	COG1247	-acetyltransferase
GMB29_11550	COG2205	protein histidine kinase activity
GMB29_11575	COG0110	maltose O-acetyltransferase activity
GMB29_11595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMB29_11665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMB29_11675	COG1802	Transcriptional regulator
GMB29_11680	COG0579	oxidoreductase
GMB29_11695	COG2814	Major facilitator Superfamily
GMB29_11700	COG0473	3-isopropylmalate dehydrogenase activity
GMB29_11705	COG0583	DNA-binding transcription factor activity
GMB29_11715	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_11720	COG1454	alcohol dehydrogenase
GMB29_11730	COG2851	Citrate transporter
GMB29_11735	COG0235	Class ii aldolase
GMB29_11740	COG3395	kinase activity
GMB29_11765	COG3773	Cell wall hydrolase
GMB29_11765	COG3409	Peptidoglycan-binding domain 1 protein
GMB29_11785	COG3655	Transcriptional regulator
GMB29_11790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GMB29_11795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GMB29_11835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GMB29_11840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_11845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_11855	COG1120	ATPase activity
GMB29_11860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GMB29_11865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_11870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_11875	COG1120	ATPase activity
GMB29_11895	COG5646	InterPro IPR014922
GMB29_11900	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
GMB29_11910	COG1476	TRANSCRIPTIONal
GMB29_11920	COG2986	histidine ammonia-lyase
GMB29_11925	COG2056	Na+-H+ antiporter family
GMB29_11930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GMB29_11935	COG2986	histidine ammonia-lyase
GMB29_11960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GMB29_11970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GMB29_11985	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GMB29_11990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GMB29_11995	COG0156	8-amino-7-oxononanoate synthase activity
GMB29_12005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GMB29_12010	COG2124	cytochrome p450
GMB29_12015	COG1733	regulation of RNA biosynthetic process
GMB29_12020	COG0778	Nitroreductase
GMB29_12055	COG1846	Transcriptional regulator
GMB29_12060	COG0456	acetyltransferase
GMB29_12065	COG2808	Putative FMN-binding domain
GMB29_12070	COG2070	2-Nitropropane dioxygenase
GMB29_12075	COG0477	Major facilitator Superfamily
GMB29_12080	COG0583	DNA-binding transcription factor activity
GMB29_12100	COG0640	Transcriptional regulator
GMB29_12105	COG0346	lactoylglutathione lyase activity
GMB29_12110	COG0561	phosphatase activity
GMB29_12115	COG1940	carbohydrate kinase activity
GMB29_12125	COG2190	(PTS) system
GMB29_12140	COG5582	Belongs to the UPF0302 family
GMB29_12145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GMB29_12160	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_12170	COG3848	Pyruvate phosphate dikinase
GMB29_12170	COG0574	Belongs to the PEP-utilizing enzyme family
GMB29_12180	COG2359	stage V sporulation protein S
GMB29_12210	COG1522	sequence-specific DNA binding
GMB29_12215	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GMB29_12220	COG1687	branched-chain amino acid
GMB29_12230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GMB29_12235	COG0697	spore germination
GMB29_12245	COG2318	DinB family
GMB29_12255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GMB29_12260	COG1228	amidohydrolase
GMB29_12265	COG0010	Belongs to the arginase family
GMB29_12270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMB29_12275	COG0583	DNA-binding transcription factor activity
GMB29_12280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GMB29_12285	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GMB29_12290	COG2031	fatty acid transporter
GMB29_12295	COG0183	Belongs to the thiolase family
GMB29_12320	COG0534	Mate efflux family protein
GMB29_12330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMB29_12335	COG3181	Tripartite tricarboxylate transporter family receptor
GMB29_12350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMB29_12355	COG1454	alcohol dehydrogenase
GMB29_12365	COG2207	Transcriptional regulator
GMB29_12365	COG4753	response regulator
GMB29_12370	COG2972	Histidine kinase
GMB29_12390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMB29_12395	COG1940	carbohydrate kinase activity
GMB29_12405	COG1053	succinate dehydrogenase
GMB29_12410	COG0583	DNA-binding transcription factor activity
GMB29_12415	COG3180	Ammonia monooxygenase
GMB29_12425	COG2851	Citrate transporter
GMB29_12430	COG0583	DNA-binding transcription factor activity
GMB29_12435	COG2828	Protein conserved in bacteria
GMB29_12445	COG4993	Dehydrogenase
GMB29_12455	COG2329	Antibiotic biosynthesis monooxygenase
GMB29_12480	COG2124	cytochrome p450
GMB29_12490	COG0431	NADPH-dependent FMN reductase
GMB29_12510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GMB29_12515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GMB29_12520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GMB29_12530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GMB29_12535	COG0765	amino acid transport
GMB29_12540	COG0765	amino acid transport
GMB29_12545	COG1126	abc transporter atp-binding protein
GMB29_12555	COG1473	amidohydrolase
GMB29_12565	COG0582	viral genome integration into host DNA
GMB29_12570	COG0490	domain, Protein
GMB29_12575	COG0475	glutathione-regulated potassium exporter activity
GMB29_12620	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_12640	COG2207	Transcriptional regulator
GMB29_12640	COG3708	Transcriptional regulator
GMB29_12655	COG0671	phosphoesterase, PA-phosphatase related
GMB29_12685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GMB29_12700	COG3773	Cell wall hydrolase
GMB29_12720	COG0583	DNA-binding transcription factor activity
GMB29_12725	COG0583	DNA-binding transcription factor activity
GMB29_12730	COG0070	glutamate synthase
GMB29_12730	COG0069	glutamate synthase activity
GMB29_12730	COG0067	glutamate synthase
GMB29_12735	COG0493	'glutamate synthase
GMB29_12740	COG5002	protein histidine kinase activity
GMB29_12765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GMB29_12780	COG2391	methyltransferase activity
GMB29_12785	COG0425	Belongs to the sulfur carrier protein TusA family
GMB29_12810	COG0436	Aminotransferase
GMB29_12815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GMB29_12820	COG2720	vancomycin resistance protein
GMB29_12825	COG3403	YqcI/YcgG family
GMB29_12830	COG0561	phosphatase activity
GMB29_12845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GMB29_12850	COG2068	MobA-Related Protein
GMB29_12855	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GMB29_12860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GMB29_12865	COG2080	2 iron, 2 sulfur cluster binding
GMB29_12875	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GMB29_12890	COG0640	Transcriptional regulator
GMB29_12915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GMB29_12930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMB29_12935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GMB29_12940	COG1368	sulfuric ester hydrolase activity
GMB29_12945	COG2814	Major facilitator Superfamily
GMB29_12960	COG0346	lactoylglutathione lyase activity
GMB29_12965	COG2356	endonuclease I
GMB29_12970	COG2135	peptidase activity
GMB29_12980	COG0656	L-ascorbic acid biosynthetic process
GMB29_12985	COG2027	D-alanyl-D-alanine carboxypeptidase
GMB29_12990	COG0702	epimerase
GMB29_12995	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GMB29_13000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GMB29_13005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GMB29_13015	COG3383	formate dehydrogenase (NAD+) activity
GMB29_13040	COG2814	Major facilitator Superfamily
GMB29_13050	COG1846	Transcriptional regulator
GMB29_13060	COG1388	LysM domain
GMB29_13060	COG3858	chitin binding
GMB29_13085	COG1335	isochorismatase
GMB29_13105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMB29_13110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMB29_13135	COG1285	pathogenesis
GMB29_13140	COG0708	Exodeoxyribonuclease III
GMB29_13150	COG5506	Protein of unknown function (DUF1694)
GMB29_13155	COG0511	ligase activity, forming carbon-carbon bonds
GMB29_13160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GMB29_13165	COG1960	acyl-CoA dehydrogenase activity
GMB29_13170	COG0439	Biotin carboxylase
GMB29_13180	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GMB29_13190	COG1492	cobalamin metabolic process
GMB29_13195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GMB29_13200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GMB29_13205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_13210	COG1120	ATPase activity
GMB29_13215	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GMB29_13220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GMB29_13230	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GMB29_13245	COG1408	metallophosphoesterase
GMB29_13250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GMB29_13270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMB29_13285	COG2323	membrane
GMB29_13300	COG1924	4 iron, 4 sulfur cluster binding
GMB29_13320	COG0726	polysaccharide deacetylase
GMB29_13365	COG0730	response to heat
GMB29_13370	COG1959	2 iron, 2 sulfur cluster binding
GMB29_13375	COG5583	Uncharacterized small protein (DUF2292)
GMB29_13380	COG2226	methyltransferase
GMB29_13385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GMB29_13390	COG0626	cystathionine gamma-synthase activity
GMB29_13395	COG2385	sporulation resulting in formation of a cellular spore
GMB29_13395	COG2247	cell wall binding repeat
GMB29_13410	COG1960	acyl-CoA dehydrogenase activity
GMB29_13415	COG3835	regulator
GMB29_13420	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMB29_13425	COG1024	Enoyl-CoA hydratase
GMB29_13430	COG0183	Belongs to the thiolase family
GMB29_13435	COG0318	PFAM AMP-dependent synthetase and ligase
GMB29_13445	COG0559	Belongs to the binding-protein-dependent transport system permease family
GMB29_13470	COG1164	Oligoendopeptidase f
GMB29_13490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GMB29_13495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GMB29_13500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GMB29_13505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GMB29_13515	COG0129	dihydroxy-acid dehydratase activity
GMB29_13520	COG1414	Transcriptional regulator
GMB29_13530	COG2721	sulfolactate sulfo-lyase activity
GMB29_13535	COG2721	sulfolactate sulfo-lyase activity
GMB29_13540	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_13545	COG4948	Mandelate Racemase Muconate Lactonizing
GMB29_13550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMB29_13565	COG0179	Fumarylacetoacetate (FAA) hydrolase
GMB29_13570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMB29_13580	COG0129	dihydroxy-acid dehydratase activity
GMB29_13595	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GMB29_13610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GMB29_13635	COG1657	PFAM Prenyltransferase squalene oxidase
GMB29_13640	COG0105	UTP biosynthetic process
GMB29_13645	COG2259	Doxx family
GMB29_13650	COG0667	Aldo Keto reductase
GMB29_13655	COG0351	phosphomethylpyrimidine kinase
GMB29_13660	COG0697	spore germination
GMB29_13665	COG0514	ATP-dependent DNA helicase (RecQ)
GMB29_13680	COG4844	belongs to the
GMB29_13700	COG0725	ABC transporter, periplasmic molybdate-binding protein
GMB29_13705	COG2318	DinB family
GMB29_13720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GMB29_13725	COG0322	excinuclease ABC activity
GMB29_13735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMB29_13740	COG4974	Belongs to the 'phage' integrase family
GMB29_13745	COG3118	belongs to the thioredoxin family
GMB29_13790	COG2116	formate transmembrane transporter activity
GMB29_13805	COG2211	Major facilitator Superfamily
GMB29_13815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GMB29_13820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GMB29_13840	COG0861	Integral membrane protein TerC family
GMB29_13855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GMB29_13860	COG0640	Transcriptional regulator
GMB29_13865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GMB29_13870	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GMB29_13875	COG0390	transport system, permease component
GMB29_13880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GMB29_13885	COG2113	Glycine betaine
GMB29_13890	COG4176	ABC-type proline glycine betaine transport system permease component
GMB29_13895	COG4175	Glycine betaine
GMB29_13895	COG0517	IMP dehydrogenase activity
GMB29_13900	COG1510	regulation of RNA biosynthetic process
GMB29_13910	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GMB29_13920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GMB29_13930	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GMB29_13935	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GMB29_13940	COG0187	DNA topoisomerase II activity
GMB29_13945	COG1832	CoA-binding protein
GMB29_13950	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GMB29_13955	COG4841	protein insertion into membrane
GMB29_13965	COG0824	Thioesterase
GMB29_13985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMB29_13990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GMB29_14010	COG0071	Belongs to the small heat shock protein (HSP20) family
GMB29_14020	COG0494	nUDIX hydrolase
GMB29_14025	COG1335	isochorismatase
GMB29_14030	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GMB29_14040	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GMB29_14045	COG1607	acyl-coa hydrolase
GMB29_14055	COG0753	catalase activity
GMB29_14060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GMB29_14080	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_14090	COG2755	lipolytic protein G-D-S-L family
GMB29_14095	COG0024	Methionine aminopeptidase
GMB29_14100	COG3852	Histidine kinase
GMB29_14105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GMB29_14130	COG1288	antiporter activity
GMB29_14135	COG1473	amidohydrolase
GMB29_14140	COG0583	DNA-binding transcription factor activity
GMB29_14145	COG0494	nUDIX hydrolase
GMB29_14150	COG2832	Protein of unknown function (DUF454)
GMB29_14190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMB29_14200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMB29_14210	COG0069	glutamate synthase activity
GMB29_14215	COG3361	conserved protein (COG2071)
GMB29_14220	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GMB29_14225	COG0814	amino acid
GMB29_14240	COG0697	spore germination
GMB29_14260	COG4846	Membrane protein involved in cytochrome C biogenesis
GMB29_14265	COG2201	protein-glutamate methylesterase activity
GMB29_14270	COG0785	Cytochrome C biogenesis protein
GMB29_14290	COG3763	UPF0154 protein
GMB29_14300	COG4224	UPF0291 protein
GMB29_14305	COG3875	lactate racemase activity
GMB29_14315	COG1929	Belongs to the glycerate kinase type-1 family
GMB29_14320	COG3835	regulator
GMB29_14325	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GMB29_14330	COG1388	LysM domain
GMB29_14335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMB29_14340	COG1357	PFAM Pentapeptide repeats (8 copies)
GMB29_14345	COG4443	Transcriptional Coactivator p15 (PC4)
GMB29_14355	COG0174	glutamine synthetase
GMB29_14360	COG0789	Transcriptional regulator
GMB29_14365	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GMB29_14370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GMB29_14375	COG2860	membrane
GMB29_14390	COG0464	growth
GMB29_14400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GMB29_14410	COG0477	Major facilitator Superfamily
GMB29_14450	COG0384	phenazine biosynthesis protein PhzF
GMB29_14470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GMB29_14475	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GMB29_14480	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GMB29_14490	COG4550	Control of competence regulator ComK, YlbF/YmcA
GMB29_14495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMB29_14555	COG4974	Belongs to the 'phage' integrase family
GMB29_14560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMB29_14565	COG0346	lactoylglutathione lyase activity
GMB29_14580	COG0701	Predicted permease
GMB29_14585	COG3689	TIGRFAM TIGR03943 family protein
GMB29_14600	COG1024	Enoyl-CoA hydratase
GMB29_14610	COG0183	Belongs to the thiolase family
GMB29_14615	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMB29_14620	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMB29_14645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_14655	COG1024	Enoyl-CoA hydratase
GMB29_14670	COG1024	Enoyl-CoA hydratase
GMB29_14675	COG0492	ferredoxin-NADP+ reductase activity
GMB29_14690	COG1137	ATPase activity
GMB29_14700	COG0559	Belongs to the binding-protein-dependent transport system permease family
GMB29_14710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_14720	COG1063	alcohol dehydrogenase
GMB29_14725	COG2217	Heavy metal translocating P-type atpase
GMB29_14730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMB29_14735	COG2244	polysaccharide biosynthetic process
GMB29_14755	COG3773	Cell wall hydrolase
GMB29_14770	COG4873	Protein conserved in bacteria
GMB29_14780	COG0582	viral genome integration into host DNA
GMB29_14795	COG0739	heme binding
GMB29_14825	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GMB29_14835	COG0720	synthase
GMB29_14840	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GMB29_14850	COG1253	flavin adenine dinucleotide binding
GMB29_14860	COG3949	Membrane
GMB29_14865	COG0542	response to heat
GMB29_14870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GMB29_14880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GMB29_14885	COG1360	Flagellar Motor Protein
GMB29_14890	COG1846	Transcriptional regulator
GMB29_14910	COG2861	carbohydrate metabolic process
GMB29_14920	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GMB29_14925	COG0235	Class ii aldolase
GMB29_14930	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GMB29_14935	COG1850	ribulose-bisphosphate carboxylase activity
GMB29_14940	COG0436	Aminotransferase
GMB29_14945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMB29_14950	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GMB29_14955	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GMB29_14960	COG5002	protein histidine kinase activity
GMB29_14965	COG3594	Acyltransferase
GMB29_14985	COG0768	penicillin binding
GMB29_14990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GMB29_14995	COG0501	Belongs to the peptidase M48B family
GMB29_15015	COG1191	sigma factor activity
GMB29_15020	COG0861	Integral membrane protein TerC family
GMB29_15030	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GMB29_15040	COG1793	dna ligase
GMB29_15040	COG3285	dna ligase
GMB29_15055	COG1175	transmembrane transport
GMB29_15060	COG1653	transport
GMB29_15065	COG1609	Transcriptional regulator
GMB29_15070	COG1846	Transcriptional regulator
GMB29_15075	COG3541	Predicted nucleotidyltransferase
GMB29_15090	COG0789	Transcriptional regulator
GMB29_15095	COG2258	MOSC domain
GMB29_15100	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GMB29_15115	COG3764	Sortase (surface protein transpeptidase)
GMB29_15145	COG1363	Peptidase, m42
GMB29_15185	COG0531	amino acid
GMB29_15190	COG0004	ammonium transporteR
GMB29_15195	COG0347	Belongs to the P(II) protein family
GMB29_15200	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GMB29_15220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GMB29_15225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GMB29_15230	COG1116	anion transmembrane transporter activity
GMB29_15235	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GMB29_15240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GMB29_15245	COG0385	Bile acid
GMB29_15250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GMB29_15260	COG2720	vancomycin resistance protein
GMB29_15265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GMB29_15275	COG2160	L-arabinose isomerase activity
GMB29_15285	COG1069	ribulokinase activity
GMB29_15300	COG1609	Transcriptional regulator
GMB29_15310	COG4214	carbohydrate transport
GMB29_15325	COG2112	serine threonine protein kinase
GMB29_15330	COG0346	lactoylglutathione lyase activity
GMB29_15335	COG2207	Transcriptional regulator
GMB29_15335	COG4753	response regulator
GMB29_15340	COG2972	Histidine kinase
GMB29_15360	COG0395	ABC-type sugar transport system, permease component
GMB29_15365	COG1175	transmembrane transport
GMB29_15390	COG1733	regulation of RNA biosynthetic process
GMB29_15395	COG2706	6-phosphogluconolactonase activity
GMB29_15400	COG0655	NAD(P)H dehydrogenase (quinone) activity
GMB29_15405	COG3152	Membrane
GMB29_15415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GMB29_15425	COG0697	spore germination
GMB29_15435	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GMB29_15450	COG1760	l-serine dehydratase
GMB29_15455	COG1760	l-serine dehydratase
GMB29_15465	COG2964	Protein conserved in bacteria
GMB29_15475	COG1486	melibiose metabolic process
GMB29_15500	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GMB29_15510	COG1132	(ABC) transporter
GMB29_15515	COG1132	(ABC) transporter
GMB29_15520	COG1695	Transcriptional regulator
GMB29_15535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GMB29_15565	COG1741	Belongs to the pirin family
GMB29_15600	COG2843	Capsule synthesis protein
GMB29_15625	COG2385	sporulation resulting in formation of a cellular spore
GMB29_15625	COG2247	cell wall binding repeat
GMB29_15630	COG2801	Transposase and inactivated derivatives
GMB29_15635	COG0584	glycerophosphoryl diester phosphodiesterase
GMB29_15650	COG4085	toxin activity
GMB29_15650	COG0737	Belongs to the 5'-nucleotidase family
GMB29_15650	COG1525	nuclease
GMB29_15670	COG0596	Alpha beta hydrolase
GMB29_15680	COG2340	Cysteine-rich secretory protein family
GMB29_15705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GMB29_15710	COG3729	General stress protein
GMB29_15720	COG2404	hydrolase activity, acting on ester bonds
GMB29_15725	COG1247	-acetyltransferase
GMB29_15735	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GMB29_15745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GMB29_15750	COG0733	neurotransmitter:sodium symporter activity
GMB29_15755	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMB29_15765	COG4548	von Willebrand factor, type A
GMB29_15770	COG0714	Associated with various cellular activities
GMB29_15775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GMB29_15780	COG1388	LysM domain
GMB29_15780	COG0791	NLP P60 protein
GMB29_15790	COG0534	Mate efflux family protein
GMB29_15800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GMB29_15805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GMB29_15815	COG2962	Rard protein
GMB29_15835	COG1733	regulation of RNA biosynthetic process
GMB29_15840	COG0778	Nitroreductase
GMB29_15845	COG3409	Peptidoglycan-binding domain 1 protein
GMB29_15845	COG0793	Belongs to the peptidase S41A family
GMB29_15855	COG2226	methyltransferase
GMB29_15865	COG3663	DNA glycosylase
GMB29_15870	COG1876	peptidase activity
GMB29_15885	COG0671	phosphoesterase, PA-phosphatase related
GMB29_15890	COG0789	Transcriptional regulator
GMB29_15900	COG4326	sporulation control protein
GMB29_15920	COG4479	Belongs to the UPF0346 family
GMB29_15935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GMB29_15935	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GMB29_15940	COG1846	Transcriptional regulator
GMB29_15965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMB29_15975	COG4698	Protein conserved in bacteria
GMB29_15980	COG2755	lipolytic protein G-D-S-L family
GMB29_15985	COG1999	signal sequence binding
GMB29_16005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GMB29_16010	COG1272	protein, Hemolysin III
GMB29_16015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GMB29_16040	COG2521	methyltransferase
GMB29_16040	COG2136	Putative SAM-dependent methyltransferase
GMB29_16050	COG1413	lyase activity
GMB29_16055	COG1418	mRNA catabolic process
GMB29_16070	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GMB29_16075	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GMB29_16080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GMB29_16085	COG1988	membrane-bound metal-dependent
GMB29_16100	COG1278	Cold shock
GMB29_16125	COG0328	RNA-DNA hybrid ribonuclease activity
GMB29_16130	COG0697	spore germination
GMB29_16145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMB29_16160	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GMB29_16170	COG1755	Isoprenylcysteine carboxyl methyltransferase
GMB29_16175	COG3424	synthase
GMB29_16205	COG2233	PERMEase
GMB29_16250	COG4974	Belongs to the 'phage' integrase family
GMB29_16255	COG2233	PERMEase
GMB29_16260	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GMB29_16265	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GMB29_16270	COG1199	ATP-dependent helicase activity
GMB29_16285	COG0116	Belongs to the methyltransferase superfamily
GMB29_16310	COG3359	exonuclease
GMB29_16315	COG1111	helicase
GMB29_16315	COG1205	dead DEAH box helicase
GMB29_16320	COG2190	(PTS) system
GMB29_16325	COG0071	Belongs to the small heat shock protein (HSP20) family
GMB29_16365	COG3331	DNA recombination
GMB29_16370	COG4499	WXG100 protein secretion system (Wss), protein YukC
GMB29_16370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GMB29_16380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GMB29_16385	COG3935	DnaD domain protein
GMB29_16390	COG0017	Asparaginyl-tRNA synthetase
GMB29_16405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GMB29_16405	COG1199	ATP-dependent helicase activity
GMB29_16410	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GMB29_16415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GMB29_16430	COG0617	tRNA 3'-terminal CCA addition
GMB29_16435	COG0438	transferase activity, transferring glycosyl groups
GMB29_16440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GMB29_16445	COG1803	Methylglyoxal synthase
GMB29_16450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GMB29_16455	COG1694	Mazg nucleotide pyrophosphohydrolase
GMB29_16465	COG4347	Protein of unknown function (DUF1405)
GMB29_16470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GMB29_16470	COG2010	Cytochrome c
GMB29_16475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GMB29_16480	COG0723	plastoquinol--plastocyanin reductase activity
GMB29_16490	COG5582	Belongs to the UPF0302 family
GMB29_16495	COG0457	Tetratricopeptide repeat
GMB29_16510	COG0287	Prephenate dehydrogenase
GMB29_16515	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GMB29_16520	COG0159	tryptophan synthase activity
GMB29_16525	COG0133	tryptophan synthase activity
GMB29_16530	COG0134	indole-3-glycerol-phosphate synthase activity
GMB29_16535	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GMB29_16540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GMB29_16545	COG4401	Chorismate mutase type I
GMB29_16550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GMB29_16555	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GMB29_16560	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GMB29_16565	COG0105	UTP biosynthetic process
GMB29_16570	COG0142	geranyltranstransferase activity
GMB29_16580	COG0142	geranyltranstransferase activity
GMB29_16595	COG0776	regulation of translation
GMB29_16600	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GMB29_16620	COG1160	GTP binding
GMB29_16645	COG1304	FMN binding
GMB29_16650	COG0539	negative regulation of cytoplasmic translation
GMB29_16655	COG0204	Acyl-transferase
GMB29_16660	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GMB29_16675	COG2959	enzyme of heme biosynthesis
GMB29_16680	COG3409	Peptidoglycan-binding domain 1 protein
GMB29_16680	COG3773	Cell wall hydrolase
GMB29_16685	COG2339	peptidase activity
GMB29_16690	COG0252	asparaginase activity
GMB29_16695	COG0492	ferredoxin-NADP+ reductase activity
GMB29_16700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMB29_16705	COG4862	establishment of competence for transformation
GMB29_16720	COG1408	metallophosphoesterase
GMB29_16730	COG1388	LysM domain
GMB29_16735	COG1266	CAAX protease self-immunity
GMB29_16740	COG0514	ATP-dependent DNA helicase (RecQ)
GMB29_16745	COG4955	Helix-turn-helix domain
GMB29_16750	COG1141	Ferredoxin
GMB29_16755	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GMB29_16760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMB29_16765	COG0739	heme binding
GMB29_16775	COG1595	DNA-templated transcription, initiation
GMB29_16780	COG2096	Adenosyltransferase
GMB29_16785	COG5002	protein histidine kinase activity
GMB29_16790	COG0745	RESPONSE REGULATOR receiver
GMB29_16795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GMB29_16800	COG1333	cytochrome c biogenesis protein
GMB29_16805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMB29_16810	COG1187	pseudouridine synthase activity
GMB29_16815	COG0700	Nucleoside recognition
GMB29_16820	COG2715	membrane protein required for spore maturation
GMB29_16825	COG1686	Belongs to the peptidase S11 family
GMB29_16830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GMB29_16835	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GMB29_16845	COG1547	Domain of unknown function (DUF309)
GMB29_16855	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GMB29_16860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMB29_16860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMB29_16865	COG0307	riboflavin synthase, alpha
GMB29_16870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMB29_16875	COG4086	secreted protein
GMB29_16880	COG0784	Response regulator, receiver
GMB29_16880	COG0835	chemotaxis
GMB29_16895	COG3706	GGDEF domain
GMB29_16910	COG0436	Aminotransferase
GMB29_16915	COG4191	Histidine kinase
GMB29_16920	COG0768	penicillin binding
GMB29_16925	COG2084	Dehydrogenase
GMB29_16935	COG0456	acetyltransferase
GMB29_16945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GMB29_16950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMB29_16955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_16955	COG1263	PTS System
GMB29_16955	COG2190	(PTS) system
GMB29_16960	COG3711	transcriptional antiterminator
GMB29_16990	COG0205	6-phosphofructokinase activity
GMB29_16995	COG1525	nuclease
GMB29_17000	COG0006	proline dipeptidase activity
GMB29_17010	COG1013	pyruvate-flavodoxin oxidoreductase activity
GMB29_17015	COG0674	pyruvate-flavodoxin oxidoreductase activity
GMB29_17015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GMB29_17025	COG2359	stage V sporulation protein S
GMB29_17030	COG1692	metallophosphoesterase
GMB29_17035	COG1418	mRNA catabolic process
GMB29_17040	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GMB29_17045	COG1058	Belongs to the CinA family
GMB29_17045	COG1546	Belongs to the CinA family
GMB29_17050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GMB29_17055	COG1426	Protein conserved in bacteria
GMB29_17070	COG0300	oxidoreductase activity
GMB29_17075	COG0612	Peptidase, M16
GMB29_17080	COG0612	Peptidase, M16
GMB29_17085	COG2814	Major facilitator Superfamily
GMB29_17105	COG1744	ABC transporter substrate-binding protein PnrA-like
GMB29_17110	COG2188	Transcriptional regulator
GMB29_17115	COG1674	ftsk spoiiie
GMB29_17115	COG4980	gas vesicle protein
GMB29_17125	COG0740	serine-type endopeptidase activity
GMB29_17130	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GMB29_17140	COG0527	aspartate kinase activity
GMB29_17145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GMB29_17150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GMB29_17155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GMB29_17160	COG1873	PFAM PRC-barrel domain
GMB29_17165	COG0612	Peptidase, M16
GMB29_17170	COG0726	polysaccharide deacetylase
GMB29_17175	COG1185	polyribonucleotide nucleotidyltransferase activity
GMB29_17185	COG0196	riboflavin kinase activity
GMB29_17190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GMB29_17200	COG1550	Protein conserved in bacteria
GMB29_17205	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GMB29_17210	COG1358	cellular component organization or biogenesis
GMB29_17215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GMB29_17220	COG0195	Participates in both transcription termination and antitermination
GMB29_17225	COG0779	Required for maturation of 30S ribosomal subunits
GMB29_17230	COG2176	DNA-directed DNA polymerase activity
GMB29_17235	COG0442	prolyl-tRNA aminoacylation
GMB29_17240	COG0750	zinc metalloprotease
GMB29_17245	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GMB29_17250	COG4589	Belongs to the CDS family
GMB29_17255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GMB29_17260	COG0233	cytoplasmic translational termination
GMB29_17275	COG0052	Belongs to the universal ribosomal protein uS2 family
GMB29_17285	COG1191	sigma factor activity
GMB29_17290	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GMB29_17295	COG1776	CheC inhibitor of MCP methylation
GMB29_17300	COG0835	chemotaxis
GMB29_17305	COG0643	Histidine kinase
GMB29_17305	COG2198	Histidine kinase
GMB29_17310	COG2201	protein-glutamate methylesterase activity
GMB29_17315	COG0455	bacterial-type flagellum organization
GMB29_17320	COG1419	protein localization to endoplasmic reticulum
GMB29_17325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GMB29_17330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GMB29_17335	COG1684	flagellar biosynthetic protein fliR
GMB29_17340	COG1987	bacterial-type flagellum assembly
GMB29_17345	COG1338	Plays a role in the flagellum-specific transport system
GMB29_17350	COG3190	flagellar
GMB29_17355	COG2201	protein-glutamate methylesterase activity
GMB29_17360	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GMB29_17360	COG1776	CheC inhibitor of MCP methylation
GMB29_17365	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GMB29_17370	COG1580	Controls the rotational direction of flagella during chemotaxis
GMB29_17375	COG1582	Flagellar protein (FlbD)
GMB29_17380	COG4786	Flagellar basal body rod
GMB29_17390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GMB29_17395	COG3144	bacterial-type flagellum assembly
GMB29_17405	COG2882	bacterial-type flagellum organization
GMB29_17410	COG1157	protein secretion by the type III secretion system
GMB29_17415	COG1317	bacterial-type flagellum organization
GMB29_17420	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GMB29_17425	COG1766	The M ring may be actively involved in energy transduction
GMB29_17430	COG1677	Flagellar hook-basal body complex protein FliE
GMB29_17435	COG1558	bacterial-type flagellum-dependent cell motility
GMB29_17440	COG1815	bacterial-type flagellum-dependent cell motility
GMB29_17445	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GMB29_17450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GMB29_17460	COG4974	Belongs to the 'phage' integrase family
GMB29_17465	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GMB29_17470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GMB29_17475	COG0758	DNA mediated transformation
GMB29_17480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GMB29_17490	COG2257	FlhB HrpN YscU SpaS Family
GMB29_17515	COG0335	large ribosomal subunit rRNA binding
GMB29_17520	COG0336	Belongs to the RNA methyltransferase TrmD family
GMB29_17525	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GMB29_17535	COG1837	Belongs to the UPF0109 family
GMB29_17540	COG0228	four-way junction DNA binding
GMB29_17545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GMB29_17550	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GMB29_17555	COG0552	protein localization to endoplasmic reticulum
GMB29_17560	COG1196	nuclear chromosome segregation
GMB29_17565	COG0571	ribonuclease III activity
GMB29_17570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMB29_17575	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_17580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GMB29_17585	COG0416	fatty acid biosynthetic process
GMB29_17590	COG1349	DNA-binding transcription factor activity
GMB29_17595	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GMB29_17600	COG1461	Dihydroxyacetone kinase
GMB29_17605	COG1302	Protein conserved in bacteria
GMB29_17610	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GMB29_17620	COG1564	THIamine pyrophosphokinase
GMB29_17625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GMB29_17635	COG0515	serine threonine protein kinase
GMB29_17635	COG2815	serine threonine protein kinase
GMB29_17640	COG0631	protein serine/threonine phosphatase activity
GMB29_17645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GMB29_17650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GMB29_17650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GMB29_17655	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GMB29_17665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GMB29_17670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GMB29_17680	COG0194	GDP metabolic process
GMB29_17685	COG2052	Domain of unknown function (DUF370)
GMB29_17690	COG1561	YicC-like family, N-terminal region
GMB29_17695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GMB29_17705	COG4193	domain, Protein
GMB29_17715	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
GMB29_17720	COG0529	Catalyzes the synthesis of activated sulfate
GMB29_17730	COG0306	phosphate transporter
GMB29_17740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GMB29_17755	COG0543	2 iron, 2 sulfur cluster binding
GMB29_17760	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GMB29_17765	COG0505	Belongs to the CarA family
GMB29_17770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMB29_17775	COG0540	Belongs to the ATCase OTCase family
GMB29_17785	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GMB29_17790	COG0564	pseudouridine synthase activity
GMB29_17795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GMB29_17805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GMB29_17810	COG3599	regulation of cell shape
GMB29_17815	COG2302	S4 RNA-binding domain
GMB29_17820	COG0762	integral membrane protein
GMB29_17825	COG1799	cell septum assembly
GMB29_17830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GMB29_17840	COG1873	PFAM PRC-barrel domain
GMB29_17845	COG1191	sigma factor activity
GMB29_17850	COG1191	sigma factor activity
GMB29_17860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GMB29_17865	COG0849	cell division
GMB29_17870	COG3856	small basic protein
GMB29_17875	COG3879	Bacterial protein of unknown function (DUF881)
GMB29_17880	COG3879	Bacterial protein of unknown function (DUF881)
GMB29_17885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GMB29_17890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GMB29_17895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GMB29_17900	COG0772	Belongs to the SEDS family
GMB29_17910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GMB29_17915	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GMB29_17920	COG0768	penicillin binding
GMB29_17930	COG4839	cell division protein FtsL
GMB29_17935	COG0275	rRNA processing
GMB29_17940	COG2001	Belongs to the MraZ family
GMB29_17945	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GMB29_17955	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GMB29_17960	COG0454	-acetyltransferase
GMB29_17970	COG1024	Enoyl-CoA hydratase
GMB29_17975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GMB29_17980	COG1399	metal-binding, possibly nucleic acid-binding protein
GMB29_17985	COG1323	Belongs to the UPF0348 family
GMB29_17990	COG3480	Lon protease (S16) C-terminal proteolytic domain
GMB29_17995	COG1752	Esterase of the alpha-beta hydrolase superfamily
GMB29_18000	COG3314	Sporulation integral membrane protein YlbJ
GMB29_18005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GMB29_18010	COG0742	ribosomal rna small subunit methyltransferase
GMB29_18025	COG3679	Belongs to the UPF0342 family
GMB29_18050	COG2340	Cysteine-rich secretory protein family
GMB29_18055	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
GMB29_18095	COG3336	cytochrome c oxidase
GMB29_18105	COG1845	cytochrome c oxidase, subunit III
GMB29_18110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GMB29_18125	COG1612	heme a metabolic process
GMB29_18130	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GMB29_18135	COG0772	Belongs to the SEDS family
GMB29_18140	COG4838	Belongs to the UPF0358 family
GMB29_18145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GMB29_18150	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GMB29_18165	COG4896	Protein conserved in bacteria
GMB29_18190	COG0483	inositol monophosphate 1-phosphatase activity
GMB29_18200	COG4493	Belongs to the UPF0637 family
GMB29_18215	COG1982	Orn Lys Arg decarboxylase major
GMB29_18225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMB29_18230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMB29_18235	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMB29_18240	COG0022	dehydrogenase e1 component
GMB29_18245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GMB29_18250	COG0497	DNA recombination
GMB29_18260	COG0242	peptide deformylase activity
GMB29_18265	COG0561	phosphatase activity
GMB29_18275	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GMB29_18280	COG0569	domain protein
GMB29_18285	COG3180	Ammonia monooxygenase
GMB29_18290	COG0514	ATP-dependent DNA helicase (RecQ)
GMB29_18300	COG1077	Cell shape determining protein MreB Mrl
GMB29_18305	COG1960	acyl-CoA dehydrogenase activity
GMB29_18310	COG2309	aminopeptidase activity
GMB29_18315	COG0523	cobalamin synthesis protein
GMB29_18320	COG0488	(ABC) transporter
GMB29_18335	COG1266	CAAX protease self-immunity
GMB29_18350	COG2801	Transposase and inactivated derivatives
GMB29_18365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_18365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_18365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMB29_18370	COG1105	Belongs to the carbohydrate kinase PfkB family
GMB29_18375	COG1349	DNA-binding transcription factor activity
GMB29_18380	COG0577	efflux transmembrane transporter activity
GMB29_18385	COG1136	(ABC) transporter
GMB29_18390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMB29_18405	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_18415	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GMB29_18420	COG0569	domain protein
GMB29_18425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GMB29_18435	COG5609	conserved protein (DUF2294)
GMB29_18450	COG0840	transmembrane signaling receptor activity
GMB29_18455	COG2176	DNA-directed DNA polymerase activity
GMB29_18465	COG0004	ammonium transporteR
GMB29_18480	COG2801	Transposase and inactivated derivatives
GMB29_18485	COG0392	lysyltransferase activity
GMB29_18485	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GMB29_18505	COG0314	molybdopterin synthase activity
GMB29_18510	COG1763	Mo-molybdopterin cofactor biosynthetic process
GMB29_18515	COG0303	'Molybdopterin
GMB29_18520	COG0746	molybdenum cofactor guanylyltransferase activity
GMB29_18525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMB29_18530	COG0450	alkyl hydroperoxide reductase
GMB29_18540	COG1473	amidohydrolase
GMB29_18545	COG2171	N-acyltransferase activity
GMB29_18550	COG0583	DNA-binding transcription factor activity
GMB29_18555	COG0477	Major facilitator Superfamily
GMB29_18560	COG0517	IMP dehydrogenase activity
GMB29_18570	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
GMB29_18575	COG4703	Protein of unknown function (DUF1797)
GMB29_18600	COG2200	EAL domain
GMB29_18605	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_18610	COG1408	metallophosphoesterase
GMB29_18620	COG0248	Ppx GppA phosphatase
GMB29_18625	COG1376	ErfK ybiS ycfS ynhG family protein
GMB29_18630	COG2814	Major facilitator Superfamily
GMB29_18640	COG0019	diaminopimelate decarboxylase activity
GMB29_18645	COG0697	spore germination
GMB29_18660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMB29_18685	COG2172	sigma factor antagonist activity
GMB29_18690	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_18695	COG1686	Belongs to the peptidase S11 family
GMB29_18710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GMB29_18715	COG4974	Belongs to the 'phage' integrase family
GMB29_18725	COG0735	belongs to the Fur family
GMB29_18730	COG1300	Membrane
GMB29_18735	COG1379	DNA repair
GMB29_18740	COG0494	nUDIX hydrolase
GMB29_18750	COG0667	Aldo Keto reductase
GMB29_18780	COG1073	alpha beta
GMB29_18795	COG4918	Iron-sulphur cluster biosynthesis
GMB29_18805	COG2755	lipolytic protein G-D-S-L family
GMB29_18810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GMB29_18820	COG0300	oxidoreductase activity
GMB29_18835	COG0300	oxidoreductase activity
GMB29_18840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_18845	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GMB29_18850	COG1234	tRNA 3'-trailer cleavage
GMB29_18855	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GMB29_18860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GMB29_18905	COG0772	Belongs to the SEDS family
GMB29_18910	COG2340	Cysteine-rich secretory protein family
GMB29_18915	COG2195	Cleaves the N-terminal amino acid of tripeptides
GMB29_18920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GMB29_18935	COG1376	ErfK ybiS ycfS ynhG family protein
GMB29_18940	COG4129	membrane
GMB29_18945	COG1126	abc transporter atp-binding protein
GMB29_18950	COG0765	amino acid transport
GMB29_18955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GMB29_18970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMB29_18970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMB29_18975	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMB29_18980	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMB29_18985	COG0022	dehydrogenase e1 component
GMB29_18990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GMB29_18995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMB29_19000	COG3426	butyrate kinase activity
GMB29_19010	COG0280	phosphate acetyltransferase
GMB29_19015	COG3829	transcription factor binding
GMB29_19015	COG3290	protein histidine kinase activity
GMB29_19025	COG0584	glycerophosphoryl diester phosphodiesterase
GMB29_19030	COG3093	addiction module antidote protein HigA
GMB29_19035	COG1116	anion transmembrane transporter activity
GMB29_19040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GMB29_19050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GMB29_19065	COG0745	RESPONSE REGULATOR receiver
GMB29_19070	COG0750	zinc metalloprotease
GMB29_19075	COG0497	DNA recombination
GMB29_19085	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GMB29_19090	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GMB29_19095	COG0142	geranyltranstransferase activity
GMB29_19100	COG1722	exodeoxyribonuclease VII activity
GMB29_19105	COG1570	exodeoxyribonuclease VII activity
GMB29_19110	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GMB29_19120	COG1302	Protein conserved in bacteria
GMB29_19125	COG0439	Biotin carboxylase
GMB29_19130	COG0511	ligase activity, forming carbon-carbon bonds
GMB29_19170	COG3854	ATPases associated with a variety of cellular activities
GMB29_19185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GMB29_19190	COG0006	proline dipeptidase activity
GMB29_19195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GMB29_19205	COG3872	metal-dependent enzyme
GMB29_19215	COG1752	Esterase of the alpha-beta hydrolase superfamily
GMB29_19220	COG1321	iron dependent repressor
GMB29_19225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GMB29_19230	COG0095	Lipoate-protein ligase
GMB29_19235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMB29_19250	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMB29_19255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GMB29_19260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMB29_19300	COG1132	(ABC) transporter
GMB29_19315	COG1408	metallophosphoesterase
GMB29_19320	COG1132	(ABC) transporter
GMB29_19335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GMB29_19355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GMB29_19385	COG1442	glycosyl transferase family 8
GMB29_19400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GMB29_19405	COG0110	maltose O-acetyltransferase activity
GMB29_19410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GMB29_19425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GMB29_19425	COG0463	Glycosyl transferase, family 2
GMB29_19430	COG0438	transferase activity, transferring glycosyl groups
GMB29_19435	COG1216	Glycosyl transferase, family 2
GMB29_19440	COG0438	transferase activity, transferring glycosyl groups
GMB29_19445	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GMB29_19460	COG0489	protein tyrosine kinase activity
GMB29_19465	COG3944	biosynthesis protein
GMB29_19470	COG1396	sequence-specific DNA binding
GMB29_19495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GMB29_19515	COG4970	Tfp pilus assembly protein FimT
GMB29_19520	COG4537	Required for transformation and DNA binding
GMB29_19525	COG1459	type II secretion system
GMB29_19530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GMB29_19560	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GMB29_19575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GMB29_19585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_19595	COG0011	TIGRFAM Protein of
GMB29_19610	COG1368	sulfuric ester hydrolase activity
GMB29_19615	COG1940	carbohydrate kinase activity
GMB29_19625	COG0697	spore germination
GMB29_19630	COG0457	Tetratricopeptide repeat
GMB29_19630	COG0705	Rhomboid family
GMB29_19640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GMB29_19645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GMB29_19665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GMB29_19670	COG0704	Plays a role in the regulation of phosphate uptake
GMB29_19680	COG0581	inorganic phosphate transmembrane transporter activity
GMB29_19685	COG0573	inorganic phosphate transmembrane transporter activity
GMB29_19690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GMB29_19695	COG0477	Major facilitator Superfamily
GMB29_19710	COG1283	sodium-dependent phosphate transmembrane transporter activity
GMB29_19715	COG5521	maltodextrose utilization protein MalA
GMB29_19720	COG0840	transmembrane signaling receptor activity
GMB29_19725	COG1388	LysM domain
GMB29_19740	COG4709	membrane
GMB29_19745	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GMB29_19750	COG0735	belongs to the Fur family
GMB29_19755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMB29_19760	COG1121	(ABC) transporter
GMB29_19770	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GMB29_19775	COG0513	Belongs to the DEAD box helicase family
GMB29_19785	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GMB29_19790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GMB29_19795	COG2384	SAM-dependent methyltransferase
GMB29_19800	COG2010	Cytochrome c
GMB29_19810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMB29_19815	COG0358	DNA primase activity
GMB29_19820	COG1671	Belongs to the UPF0178 family
GMB29_19825	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GMB29_19830	COG0517	IMP dehydrogenase activity
GMB29_19835	COG0751	glycine-tRNA ligase activity
GMB29_19845	COG1381	Involved in DNA repair and RecF pathway recombination
GMB29_19855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GMB29_19860	COG0295	cytidine deaminase activity
GMB29_19865	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GMB29_19875	COG1480	7TM receptor with intracellular HD hydrolase
GMB29_19880	COG1702	phosphate starvation-inducible protein PhoH
GMB29_19900	COG4864	UPF0365 protein
GMB29_19905	COG1030	water channel activity
GMB29_19910	COG1610	YqeY-like protein
GMB29_19915	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GMB29_19920	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GMB29_19925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMB29_19930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GMB29_19935	COG2264	protein methyltransferase activity
GMB29_19940	COG0484	heat shock protein binding
GMB29_19945	COG0443	Heat shock 70 kDa protein
GMB29_19950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GMB29_19960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMB29_19965	COG0481	GTPase activity
GMB29_19975	COG0860	N-Acetylmuramoyl-L-alanine amidase
GMB29_19980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GMB29_19990	COG1466	dna polymerase III delta subunit
GMB29_20000	COG2333	competence protein COMEC
GMB29_20000	COG0658	competence protein
GMB29_20005	COG2131	deaminase
GMB29_20010	COG1596	polysaccharide export
GMB29_20010	COG1555	photosystem II stabilization
GMB29_20015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GMB29_20020	COG2226	methyltransferase
GMB29_20025	COG0799	negative regulation of ribosome biogenesis
GMB29_20030	COG1713	HD superfamily hydrolase involved in NAD metabolism
GMB29_20040	COG1534	Rna-binding protein
GMB29_20045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GMB29_20050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GMB29_20055	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GMB29_20080	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GMB29_20095	COG0768	penicillin binding
GMB29_20100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GMB29_20105	COG0572	uridine kinase
GMB29_20115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GMB29_20120	COG3906	Belongs to the UPF0473 family
GMB29_20125	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GMB29_20130	COG4472	Bacterial protein of unknown function (DUF965)
GMB29_20135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GMB29_20140	COG0628	permease
GMB29_20155	COG3881	PFAM PRC-barrel domain
GMB29_20160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GMB29_20170	COG0482	sulfurtransferase activity
GMB29_20175	COG1104	cysteine desulfurase activity
GMB29_20180	COG1959	2 iron, 2 sulfur cluster binding
GMB29_20185	COG2364	Membrane
GMB29_20190	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GMB29_20200	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GMB29_20210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GMB29_20215	COG0124	histidyl-tRNA synthetase
GMB29_20220	COG4991	sh3 domain protein
GMB29_20220	COG3103	Sh3 type 3 domain protein
GMB29_20220	COG0860	N-Acetylmuramoyl-L-alanine amidase
GMB29_20225	COG1490	D-aminoacyl-tRNA deacylase activity
GMB29_20230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GMB29_20235	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GMB29_20240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GMB29_20240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GMB29_20250	COG2244	polysaccharide biosynthetic process
GMB29_20255	COG2323	membrane
GMB29_20265	COG1862	Preprotein translocase
GMB29_20275	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GMB29_20285	COG2255	four-way junction helicase activity
GMB29_20290	COG0632	four-way junction helicase activity
GMB29_20315	COG1388	LysM domain
GMB29_20325	COG0157	Belongs to the NadC ModD family
GMB29_20330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GMB29_20335	COG1104	cysteine desulfurase activity
GMB29_20340	COG1827	regulation of RNA biosynthetic process
GMB29_20345	COG0077	Prephenate dehydratase
GMB29_20350	COG4492	Belongs to the UPF0735 family
GMB29_20355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GMB29_20360	COG3290	protein histidine kinase activity
GMB29_20365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GMB29_20370	COG2868	ribosomal protein
GMB29_20375	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GMB29_20380	COG1530	ribonuclease E activity
GMB29_20385	COG1994	Peptidase M50
GMB29_20390	COG0739	heme binding
GMB29_20395	COG2894	cell division
GMB29_20400	COG0850	regulation of cytokinetic process
GMB29_20405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GMB29_20410	COG1792	Involved in formation and maintenance of cell shape
GMB29_20415	COG1077	Cell shape determining protein MreB Mrl
GMB29_20420	COG2003	Belongs to the UPF0758 family
GMB29_20440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GMB29_20450	COG0285	dihydrofolate synthase activity
GMB29_20455	COG0525	valine-tRNA ligase activity
GMB29_20465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GMB29_20470	COG1388	LysM domain
GMB29_20470	COG1388	LysM domain
GMB29_20475	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GMB29_20480	COG0113	porphobilinogen synthase activity
GMB29_20485	COG1587	Uroporphyrinogen-III synthase
GMB29_20490	COG0181	hydroxymethylbilane synthase activity
GMB29_20495	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GMB29_20510	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GMB29_20515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GMB29_20520	COG1067	ATP-dependent peptidase activity
GMB29_20520	COG0470	DNA polymerase III
GMB29_20525	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GMB29_20530	COG0544	peptidyl-prolyl cis-trans isomerase activity
GMB29_20535	COG1477	protein flavinylation
GMB29_20535	COG0457	Tetratricopeptide repeat
GMB29_20540	COG0066	3-isopropylmalate dehydratase activity
GMB29_20545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GMB29_20550	COG0473	3-isopropylmalate dehydrogenase activity
GMB29_20555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GMB29_20560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GMB29_20565	COG0440	acetolactate synthase activity
GMB29_20570	COG0028	Belongs to the TPP enzyme family
GMB29_20580	COG0622	Phosphoesterase
GMB29_20585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GMB29_20590	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GMB29_20595	COG5401	PFAM Sporulation and spore germination
GMB29_20605	COG2197	response regulator
GMB29_20615	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GMB29_20620	COG1053	succinate dehydrogenase
GMB29_20625	COG2009	succinate dehydrogenase
GMB29_20630	COG1719	4-vinyl reductase, 4VR
GMB29_20645	COG3118	belongs to the thioredoxin family
GMB29_20650	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GMB29_20655	COG2086	electron transfer activity
GMB29_20660	COG1024	Enoyl-CoA hydratase
GMB29_20665	COG1309	transcriptional regulator
GMB29_20670	COG0318	PFAM AMP-dependent synthetase and ligase
GMB29_20675	COG3766	membrane
GMB29_20680	COG1193	negative regulation of DNA recombination
GMB29_20685	COG1796	DNA polymerase
GMB29_20685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GMB29_20690	COG1286	toxin biosynthetic process
GMB29_20695	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GMB29_20700	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GMB29_20705	COG0072	phenylalanine-tRNA ligase activity
GMB29_20705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMB29_20710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GMB29_20715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GMB29_20725	COG1363	Peptidase, m42
GMB29_20745	COG3326	Membrane
GMB29_20750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GMB29_20760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GMB29_20765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GMB29_20775	COG1484	DNA-dependent DNA replication
GMB29_20780	COG3611	Membrane attachment protein
GMB29_20785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GMB29_20795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GMB29_20800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GMB29_20810	COG1971	Probably functions as a manganese efflux pump
GMB29_20815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GMB29_20820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMB29_20820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMB29_20825	COG0330	HflC and HflK could
GMB29_20830	COG0330	HflC and HflK could
GMB29_20835	COG5002	protein histidine kinase activity
GMB29_20840	COG0745	RESPONSE REGULATOR receiver
GMB29_20850	COG0039	L-malate dehydrogenase activity
GMB29_20855	COG0538	isocitrate dehydrogenase activity
GMB29_20860	COG0372	Belongs to the citrate synthase family
GMB29_20865	COG2707	UPF0756 membrane protein
GMB29_20870	COG0628	permease
GMB29_20875	COG3030	protein affecting phage T7 exclusion by the F plasmid
GMB29_20885	COG0205	6-phosphofructokinase activity
GMB29_20890	COG0825	malonyl-CoA metabolic process
GMB29_20895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GMB29_20900	COG1725	Transcriptional regulator
GMB29_20905	COG0281	malic enzyme
GMB29_20910	COG0587	DNA-directed DNA polymerase activity
GMB29_20930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GMB29_20940	COG4109	DRTGG domain
GMB29_20950	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GMB29_20960	COG0165	Argininosuccinate lyase
GMB29_20965	COG0137	argininosuccinate synthase activity
GMB29_20975	COG0521	Mo-molybdopterin cofactor biosynthetic process
GMB29_20985	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GMB29_20990	COG0827	DNA restriction-modification system
GMB29_20995	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GMB29_21000	COG3874	Sporulation protein YtfJ
GMB29_21010	COG1714	RDD family
GMB29_21015	COG0616	signal peptide processing
GMB29_21020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GMB29_21025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GMB29_21035	COG0301	tRNA thio-modification
GMB29_21040	COG1104	cysteine desulfurase activity
GMB29_21045	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GMB29_21050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GMB29_21055	COG1309	transcriptional regulator
GMB29_21060	COG1956	GAF domain-containing protein
GMB29_21065	COG2203	Gaf domain
GMB29_21065	COG2199	diguanylate cyclase activity
GMB29_21070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GMB29_21080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GMB29_21090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GMB29_21095	COG0454	-acetyltransferase
GMB29_21100	COG0517	IMP dehydrogenase activity
GMB29_21105	COG0123	including yeast histone deacetylase and acetoin utilization protein
GMB29_21115	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GMB29_21115	COG1605	Chorismate mutase
GMB29_21120	COG3118	belongs to the thioredoxin family
GMB29_21125	COG4980	gas vesicle protein
GMB29_21130	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GMB29_21135	COG2309	aminopeptidase activity
GMB29_21145	COG1131	(ABC) transporter
GMB29_21160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GMB29_21170	COG1674	ftsk spoiiie
GMB29_21175	COG4848	Belongs to the UPF0354 family
GMB29_21180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMB29_21190	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GMB29_21195	COG1363	Peptidase, m42
GMB29_21200	COG5584	Small secreted protein
GMB29_21205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_21210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GMB29_21220	COG0510	thiamine kinase activity
GMB29_21225	COG1523	belongs to the glycosyl hydrolase 13 family
GMB29_21230	COG1597	lipid kinase activity
GMB29_21240	COG1346	cytolysis
GMB29_21245	COG1380	Effector of murein hydrolase LrgA
GMB29_21255	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GMB29_21265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GMB29_21270	COG2252	PERMEase
GMB29_21275	COG0024	Methionine aminopeptidase
GMB29_21280	COG1349	DNA-binding transcription factor activity
GMB29_21285	COG1187	pseudouridine synthase activity
GMB29_21290	COG2244	polysaccharide biosynthetic process
GMB29_21295	COG2081	HI0933 family
GMB29_21305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMB29_21310	COG0495	leucyl-tRNA aminoacylation
GMB29_21315	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_21320	COG2610	gluconate transmembrane transporter activity
GMB29_21325	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GMB29_21330	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GMB29_21340	COG2814	Major facilitator Superfamily
GMB29_21345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GMB29_21350	COG0577	efflux transmembrane transporter activity
GMB29_21355	COG1136	(ABC) transporter
GMB29_21370	COG1131	(ABC) transporter
GMB29_21375	COG1725	Transcriptional regulator
GMB29_21390	COG1242	4 iron, 4 sulfur cluster binding
GMB29_21395	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GMB29_21405	COG1120	ATPase activity
GMB29_21410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GMB29_21415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_21420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_21430	COG2267	carboxylic ester hydrolase activity
GMB29_21435	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GMB29_21440	COG0671	phosphoesterase, PA-phosphatase related
GMB29_21445	COG0438	transferase activity, transferring glycosyl groups
GMB29_21460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GMB29_21465	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GMB29_21475	COG1506	peptidase
GMB29_21480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GMB29_21485	COG1116	anion transmembrane transporter activity
GMB29_21490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GMB29_21495	COG0494	nUDIX hydrolase
GMB29_21510	COG0783	Belongs to the Dps family
GMB29_21520	COG1469	GTP cyclohydrolase I activity
GMB29_21525	COG1854	S-ribosylhomocysteine lyase activity
GMB29_21530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GMB29_21535	COG0288	reversible hydration of carbon dioxide
GMB29_21560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMB29_21565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMB29_21565	COG1321	iron dependent repressor
GMB29_21570	COG1121	(ABC) transporter
GMB29_21575	COG0803	Belongs to the bacterial solute-binding protein 9 family
GMB29_21580	COG4948	Mandelate Racemase Muconate Lactonizing
GMB29_21585	COG0318	PFAM AMP-dependent synthetase and ligase
GMB29_21590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GMB29_21595	COG0596	Alpha beta hydrolase
GMB29_21600	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GMB29_21605	COG1169	isochorismate synthase
GMB29_21610	COG1575	Belongs to the MenA family. Type 1 subfamily
GMB29_21615	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GMB29_21625	COG0058	SHG alpha-glucan phosphorylase activity
GMB29_21630	COG0297	glycogen (starch) synthase activity
GMB29_21635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GMB29_21810	COG1132	(ABC) transporter
GMB29_21825	COG1609	Transcriptional regulator
GMB29_21845	COG0183	Belongs to the thiolase family
GMB29_21850	COG0318	PFAM AMP-dependent synthetase and ligase
GMB29_21855	COG1268	BioY protein
GMB29_21860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMB29_21870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GMB29_21875	COG1278	Cold shock
GMB29_21890	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMB29_21895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GMB29_21905	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GMB29_21910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMB29_21915	COG0326	Molecular chaperone. Has ATPase activity
GMB29_21960	COG2045	Belongs to the ComB family
GMB29_21965	COG2707	UPF0756 membrane protein
GMB29_21970	COG2814	Major facilitator Superfamily
GMB29_21975	COG1809	phosphosulfolactate synthase activity
GMB29_21990	COG0778	Nitroreductase
GMB29_21995	COG0492	ferredoxin-NADP+ reductase activity
GMB29_22000	COG2259	Doxx family
GMB29_22005	COG3384	dioxygenase
GMB29_22025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GMB29_22030	COG1396	sequence-specific DNA binding
GMB29_22055	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_22075	COG2423	ornithine cyclodeaminase activity
GMB29_22080	COG0006	proline dipeptidase activity
GMB29_22085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GMB29_22090	COG2508	Transcriptional regulator
GMB29_22095	COG1027	Aspartate ammonia-lyase
GMB29_22100	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GMB29_22105	COG0584	glycerophosphoryl diester phosphodiesterase
GMB29_22110	COG3584	3D domain protein
GMB29_22110	COG1388	LysM domain
GMB29_22115	COG1473	amidohydrolase
GMB29_22120	COG2271	Major facilitator Superfamily
GMB29_22140	COG0583	DNA-binding transcription factor activity
GMB29_22150	COG3695	enzyme binding
GMB29_22170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GMB29_22185	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GMB29_22205	COG0861	Integral membrane protein TerC family
GMB29_22210	COG5002	protein histidine kinase activity
GMB29_22210	COG3850	Histidine kinase
GMB29_22215	COG0745	RESPONSE REGULATOR receiver
GMB29_22220	COG0577	efflux transmembrane transporter activity
GMB29_22225	COG0577	efflux transmembrane transporter activity
GMB29_22225	COG1136	(ABC) transporter
GMB29_22235	COG4585	Histidine kinase
GMB29_22240	COG2197	response regulator
GMB29_22290	COG1966	Carbon starvation protein
GMB29_22295	COG3279	Response regulator of the LytR AlgR family
GMB29_22300	COG3275	phosphorelay sensor kinase activity
GMB29_22315	COG0531	amino acid
GMB29_22325	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GMB29_22325	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GMB29_22340	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_22350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMB29_22355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GMB29_22360	COG3829	transcription factor binding
GMB29_22365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GMB29_22375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GMB29_22380	COG2264	protein methyltransferase activity
GMB29_22385	COG3507	Belongs to the glycosyl hydrolase 43 family
GMB29_22390	COG0667	Aldo Keto reductase
GMB29_22395	COG5578	integral membrane protein
GMB29_22405	COG1175	transmembrane transport
GMB29_22410	COG1653	transport
GMB29_22415	COG0745	RESPONSE REGULATOR receiver
GMB29_22420	COG2972	Histidine kinase
GMB29_22425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMB29_22430	COG5002	protein histidine kinase activity
GMB29_22430	COG3850	Histidine kinase
GMB29_22435	COG0745	RESPONSE REGULATOR receiver
GMB29_22440	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_22445	COG1113	amino acid transport
GMB29_22450	COG0800	Aldolase
GMB29_22455	COG2140	Oxalate decarboxylase
GMB29_22465	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GMB29_22470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GMB29_22475	COG0363	glucosamine-6-phosphate deaminase activity
GMB29_22480	COG1063	alcohol dehydrogenase
GMB29_22485	COG1064	alcohol dehydrogenase
GMB29_22490	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_22495	COG1129	ABC transporter
GMB29_22505	COG0546	phosphoglycolate phosphatase activity
GMB29_22510	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_22515	COG1105	Belongs to the carbohydrate kinase PfkB family
GMB29_22520	COG1063	alcohol dehydrogenase
GMB29_22525	COG1070	Carbohydrate kinase
GMB29_22535	COG1070	Carbohydrate kinase
GMB29_22545	COG1082	Xylose isomerase domain protein TIM barrel
GMB29_22555	COG1301	dicarboxylic acid transport
GMB29_22560	COG1752	Esterase of the alpha-beta hydrolase superfamily
GMB29_22565	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GMB29_22570	COG3290	protein histidine kinase activity
GMB29_22580	COG1278	Cold shock
GMB29_22590	COG1033	growth of symbiont in host cell
GMB29_22590	COG2409	Drug exporters of the RND superfamily
GMB29_22595	COG1846	Transcriptional regulator
GMB29_22600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMB29_22615	COG0432	Pfam Uncharacterised protein family UPF0047
GMB29_22620	COG5002	protein histidine kinase activity
GMB29_22625	COG0745	RESPONSE REGULATOR receiver
GMB29_22645	COG3706	GGDEF domain
GMB29_22645	COG0745	RESPONSE REGULATOR receiver
GMB29_22655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GMB29_22665	COG0166	Belongs to the GPI family
GMB29_22670	COG1979	alcohol dehydrogenase
GMB29_22675	COG2155	Conserved Protein
GMB29_22680	COG1098	S1 RNA binding domain
GMB29_22695	COG0436	Aminotransferase
GMB29_22700	COG1522	sequence-specific DNA binding
GMB29_22705	COG2267	carboxylic ester hydrolase activity
GMB29_22715	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GMB29_22720	COG2205	protein histidine kinase activity
GMB29_22725	COG2032	superoxide dismutase activity
GMB29_22740	COG5018	Exonuclease
GMB29_22745	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_22750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GMB29_22755	COG3011	Protein conserved in bacteria
GMB29_22770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GMB29_22770	COG2111	Na H antiporter
GMB29_22775	COG2111	Na H antiporter
GMB29_22780	COG1006	Multisubunit Na H antiporter MnhC subunit
GMB29_22785	COG0651	ATP synthesis coupled electron transport
GMB29_22790	COG1863	multisubunit Na H antiporter MnhE subunit
GMB29_22795	COG2212	antiporter activity
GMB29_22800	COG1320	monovalent cation:proton antiporter activity
GMB29_22805	COG2050	protein possibly involved in aromatic compounds catabolism
GMB29_22810	COG2197	response regulator
GMB29_22815	COG4585	Histidine kinase
GMB29_22825	COG0142	geranyltranstransferase activity
GMB29_22840	COG0861	Integral membrane protein TerC family
GMB29_22845	COG2368	4-hydroxyphenylacetate
GMB29_22860	COG0628	permease
GMB29_22865	COG2738	Putative neutral zinc metallopeptidase
GMB29_22870	COG1418	mRNA catabolic process
GMB29_22875	COG3290	protein histidine kinase activity
GMB29_22880	COG1028	Short-chain dehydrogenase reductase Sdr
GMB29_22910	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GMB29_22915	COG1268	BioY protein
GMB29_22930	COG2056	Na+-H+ antiporter family
GMB29_22935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GMB29_22940	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GMB29_22950	COG3584	3D domain protein
GMB29_22965	COG1252	NADH dehydrogenase
GMB29_22970	COG0492	ferredoxin-NADP+ reductase activity
GMB29_22975	COG0316	Belongs to the HesB IscA family
GMB29_22980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GMB29_22990	COG1252	NADH dehydrogenase
GMB29_22995	COG4837	Protein of unknown function (DUF1462)
GMB29_23000	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GMB29_23005	COG0083	homoserine kinase activity
GMB29_23010	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GMB29_23015	COG0460	homoserine dehydrogenase
GMB29_23020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GMB29_23025	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GMB29_23030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GMB29_23035	COG0647	UMP catabolic process
GMB29_23040	COG2445	Protein of unknown function DUF86
GMB29_23045	COG5001	Diguanylate cyclase
GMB29_23055	COG4470	Protein conserved in bacteria
GMB29_23065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GMB29_23070	COG0739	heme binding
GMB29_23080	COG3377	Domain of unknown function (DUF1805)
GMB29_23085	COG0737	Belongs to the 5'-nucleotidase family
GMB29_23090	COG0730	response to heat
GMB29_23095	COG1801	Protein of unknown function DUF72
GMB29_23100	COG0719	Fe-S assembly protein
GMB29_23105	COG0822	iron-sulfur transferase activity
GMB29_23110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GMB29_23115	COG0719	Fe-S assembly protein
GMB29_23120	COG0396	ATPase activity
GMB29_23125	COG1464	Belongs to the NlpA lipoprotein family
GMB29_23130	COG2011	ABC-type metal ion transport system permease component
GMB29_23135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GMB29_23145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMB29_23150	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GMB29_23155	COG0509	glycine decarboxylation via glycine cleavage system
GMB29_23160	COG1393	Belongs to the ArsC family
GMB29_23165	COG1960	acyl-CoA dehydrogenase activity
GMB29_23170	COG0183	Belongs to the thiolase family
GMB29_23175	COG1024	Enoyl-CoA hydratase
GMB29_23175	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMB29_23195	COG5577	PFAM Coat F domain
GMB29_23210	COG1120	ATPase activity
GMB29_23215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_23220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMB29_23225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GMB29_23245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMB29_23250	COG1686	Belongs to the peptidase S11 family
GMB29_23260	COG2076	Multidrug Resistance protein
GMB29_23265	COG2076	Multidrug Resistance protein
GMB29_23290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMB29_23295	COG0745	RESPONSE REGULATOR receiver
GMB29_23300	COG2770	Histidine kinase
GMB29_23300	COG2205	protein histidine kinase activity
GMB29_23305	COG0840	transmembrane signaling receptor activity
GMB29_23315	COG0446	pyridine nucleotide-disulphide oxidoreductase
GMB29_23335	COG0745	RESPONSE REGULATOR receiver
GMB29_23340	COG5002	protein histidine kinase activity
GMB29_23355	COG2608	mercury ion transmembrane transporter activity
GMB29_23370	COG2217	Heavy metal translocating P-type atpase
GMB29_23385	COG2814	Major facilitator Superfamily
GMB29_23390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GMB29_23395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GMB29_23400	COG0765	amino acid transport
GMB29_23405	COG1126	abc transporter atp-binding protein
GMB29_23410	COG0534	Mate efflux family protein
GMB29_23415	COG4608	Belongs to the ABC transporter superfamily
GMB29_23420	COG0444	Belongs to the ABC transporter superfamily
GMB29_23425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GMB29_23430	COG0601	transmembrane transport
GMB29_23435	COG0747	negative chemotaxis
GMB29_23440	COG0693	protein deglycase activity
GMB29_23450	COG2390	Transcriptional regulator
GMB29_23455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GMB29_23460	COG0205	6-phosphofructokinase activity
GMB29_23465	COG3852	Histidine kinase
GMB29_23480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GMB29_23495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GMB29_23500	COG0523	cobalamin synthesis protein
GMB29_23505	COG3883	PFAM NLP P60 protein
GMB29_23505	COG0791	NLP P60 protein
GMB29_23520	COG1619	proteins homologs of microcin C7 resistance protein MccF
GMB29_23525	COG4335	DNA alkylation repair
GMB29_23535	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GMB29_23540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GMB29_23555	COG0640	Transcriptional regulator
GMB29_23560	COG3832	glyoxalase III activity
GMB29_23575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GMB29_23580	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GMB29_23600	COG2226	methyltransferase
GMB29_23605	COG4565	transcriptional regulatory protein
GMB29_23610	COG3290	protein histidine kinase activity
GMB29_23620	COG1131	(ABC) transporter
GMB29_23625	COG1511	domain protein
GMB29_23625	COG0842	Transport permease protein
GMB29_23630	COG1309	transcriptional regulator
GMB29_23650	COG2814	Major facilitator Superfamily
GMB29_23670	COG2814	Major facilitator Superfamily
GMB29_23675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GMB29_23685	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GMB29_23690	COG0412	Dienelactone hydrolase
GMB29_23700	COG1968	undecaprenyl-diphosphatase activity
GMB29_23705	COG0586	Pfam SNARE associated Golgi protein
GMB29_23710	COG0577	efflux transmembrane transporter activity
GMB29_23715	COG1136	(ABC) transporter
GMB29_23720	COG2205	protein histidine kinase activity
GMB29_23725	COG0745	RESPONSE REGULATOR receiver
GMB29_23740	COG1252	NADH dehydrogenase
GMB29_23750	COG0590	tRNA wobble adenosine to inosine editing
GMB29_23755	COG0666	response to abiotic stimulus
GMB29_23770	COG0517	IMP dehydrogenase activity
GMB29_23795	COG1295	ribonuclease BN
GMB29_23805	COG0477	Major facilitator Superfamily
GMB29_23830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GMB29_23850	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GMB29_23855	COG0557	exoribonuclease II activity
GMB29_23860	COG1647	Serine aminopeptidase, S33
GMB29_23865	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GMB29_23870	COG0148	phosphopyruvate hydratase activity
GMB29_23875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GMB29_23885	COG0126	phosphoglycerate kinase activity
GMB29_23890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GMB29_23905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GMB29_23930	COG3773	Cell wall hydrolase
GMB29_23930	COG3409	Peptidoglycan-binding domain 1 protein
GMB29_23960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMB29_23965	COG1481	regulation of sporulation
GMB29_23970	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GMB29_23975	COG1660	Displays ATPase and GTPase activities
GMB29_23980	COG1051	belongs to the nudix hydrolase family
GMB29_23985	COG0492	ferredoxin-NADP+ reductase activity
GMB29_23990	COG0457	Tetratricopeptide repeat
GMB29_23995	COG0140	phosphoribosyl-ATP diphosphatase activity
GMB29_23995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GMB29_24000	COG0107	imidazoleglycerol-phosphate synthase activity
GMB29_24005	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GMB29_24010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GMB29_24015	COG0131	Imidazoleglycerol-phosphate dehydratase
GMB29_24020	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GMB29_24030	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GMB29_24035	COG0110	maltose O-acetyltransferase activity
GMB29_24040	COG0546	phosphoglycolate phosphatase activity
GMB29_24045	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GMB29_24050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GMB29_24055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GMB29_24070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GMB29_24075	COG1950	PFAM Membrane protein of
GMB29_24080	COG1983	PspC domain protein
GMB29_24085	COG3595	metallopeptidase activity
GMB29_24095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GMB29_24105	COG4897	Protein conserved in bacteria
GMB29_24110	COG0456	acetyltransferase
GMB29_24115	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GMB29_24125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GMB29_24130	COG1309	transcriptional regulator
GMB29_24135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMB29_24145	COG0531	amino acid
GMB29_24150	COG2839	Protein conserved in bacteria
GMB29_24160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMB29_24165	COG3711	transcriptional antiterminator
GMB29_24175	COG0469	pyruvate kinase activity
GMB29_24195	COG1404	Belongs to the peptidase S8 family
GMB29_24220	COG0395	ABC-type sugar transport system, permease component
GMB29_24245	COG1802	Transcriptional regulator
GMB29_24255	COG2271	Major facilitator Superfamily
GMB29_24260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMB29_24265	COG4974	Belongs to the 'phage' integrase family
GMB29_24275	COG0671	phosphoesterase, PA-phosphatase related
GMB29_24305	COG0778	Nitroreductase
GMB29_24315	COG1113	amino acid transport
GMB29_24345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMB29_24355	COG3409	Peptidoglycan-binding domain 1 protein
GMB29_24355	COG0793	Belongs to the peptidase S41A family
GMB29_24360	COG0739	heme binding
GMB29_24365	COG2177	Part of the ABC transporter FtsEX involved in
GMB29_24370	COG2884	Cell division ATP-binding protein ftsE
GMB29_24375	COG2010	Cytochrome c
GMB29_24380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GMB29_24390	COG0653	protein targeting
GMB29_24395	COG1879	ABC-type sugar transport system periplasmic component
GMB29_24400	COG1172	Belongs to the binding-protein-dependent transport system permease family
GMB29_24405	COG1129	ABC transporter
GMB29_24410	COG1869	D-ribose catabolic process
GMB29_24415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GMB29_24420	COG1609	Transcriptional regulator
GMB29_24425	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GMB29_24440	COG1516	flagellar protein fliS
GMB29_24445	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GMB29_24450	COG1334	flagellar protein FlaG
GMB29_24470	COG2084	Dehydrogenase
GMB29_24485	COG5002	protein histidine kinase activity
GMB29_24505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GMB29_24510	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GMB29_24520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GMB29_24525	COG1256	bacterial-type flagellum assembly
GMB29_24525	COG4786	Flagellar basal body rod
GMB29_24530	COG3418	PFAM FlgN family protein
GMB29_24545	COG1040	competence protein
GMB29_24555	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GMB29_24565	COG1307	EDD domain protein, DegV family
GMB29_24570	COG2197	response regulator
GMB29_24575	COG4585	Histidine kinase
GMB29_24580	COG1739	Uncharacterized protein family UPF0029
GMB29_24585	COG1316	TRANSCRIPTIONal
GMB29_24590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GMB29_24595	COG1215	transferase activity, transferring glycosyl groups
GMB29_24605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GMB29_24630	COG0517	IMP dehydrogenase activity
GMB29_24630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GMB29_24640	COG0438	transferase activity, transferring glycosyl groups
GMB29_24655	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GMB29_24670	COG2866	Carboxypeptidase
GMB29_24680	COG1404	Belongs to the peptidase S8 family
GMB29_24685	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GMB29_24690	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GMB29_24690	COG0517	IMP dehydrogenase activity
GMB29_24695	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GMB29_24730	COG1316	TRANSCRIPTIONal
GMB29_24760	COG3212	peptidase
GMB29_24765	COG5002	protein histidine kinase activity
GMB29_24765	COG3850	Histidine kinase
GMB29_24770	COG0745	RESPONSE REGULATOR receiver
GMB29_24785	COG3853	Toxic anion resistance protein (TelA)
GMB29_24790	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GMB29_24795	COG1405	negative regulation of cell septum assembly
GMB29_24795	COG3012	SEC-C Motif Domain Protein
GMB29_24810	COG1842	Phage shock protein A
GMB29_24820	COG3766	membrane
GMB29_24825	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GMB29_24830	COG0584	glycerophosphoryl diester phosphodiesterase
GMB29_24920	COG0531	amino acid
GMB29_24940	COG2017	converts alpha-aldose to the beta-anomer
GMB29_24945	COG2814	Major facilitator Superfamily
GMB29_24945	COG0477	Major facilitator Superfamily
GMB29_24950	COG1070	Carbohydrate kinase
GMB29_24955	COG2115	Belongs to the xylose isomerase family
GMB29_24975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GMB29_24975	COG2199	diguanylate cyclase activity
GMB29_24985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GMB29_25000	COG4608	Belongs to the ABC transporter superfamily
GMB29_25005	COG0444	Belongs to the ABC transporter superfamily
GMB29_25070	COG0395	ABC-type sugar transport system, permease component
GMB29_25085	COG1472	Belongs to the glycosyl hydrolase 3 family
GMB29_25090	COG3459	Glycosyltransferase 36 associated
GMB29_25095	COG1609	Transcriptional regulator
GMB29_25105	COG3459	Glycosyltransferase 36 associated
GMB29_25110	COG0584	glycerophosphoryl diester phosphodiesterase
GMB29_25115	COG5002	protein histidine kinase activity
GMB29_25125	COG1136	(ABC) transporter
GMB29_25130	COG0577	efflux transmembrane transporter activity
GMB29_25135	COG1316	TRANSCRIPTIONal
GMB29_25145	COG1940	carbohydrate kinase activity
GMB29_25150	COG1482	cell wall glycoprotein biosynthetic process
GMB29_25160	COG0191	fructose-bisphosphate aldolase activity
GMB29_25165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_25165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_25170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_25170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_25170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMB29_25175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_25175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GMB29_25175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GMB29_25205	COG0438	transferase activity, transferring glycosyl groups
GMB29_25210	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GMB29_25220	COG1086	Polysaccharide biosynthesis protein
GMB29_25245	COG4464	protein tyrosine phosphatase activity
GMB29_25250	COG0489	protein tyrosine kinase activity
GMB29_25255	COG3944	biosynthesis protein
GMB29_25275	COG4715	Zinc finger, swim domain protein
GMB29_25280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GMB29_25285	COG0434	BtpA family
GMB29_25310	COG3964	amidohydrolase
GMB29_25315	COG2188	Transcriptional regulator
GMB29_25350	COG1523	belongs to the glycosyl hydrolase 13 family
GMB29_25370	COG0702	epimerase
GMB29_25375	COG1175	transmembrane transport
GMB29_25390	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GMB29_25405	COG1012	belongs to the aldehyde dehydrogenase family
GMB29_25420	COG0673	inositol 2-dehydrogenase activity
GMB29_25425	COG1653	transport
GMB29_25430	COG1175	transmembrane transport
GMB29_25445	COG1501	Belongs to the glycosyl hydrolase 31 family
GMB29_25450	COG2211	Major facilitator Superfamily
GMB29_25460	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GMB29_25465	COG0629	single-stranded DNA binding
GMB29_25475	COG3546	catalase activity
GMB29_25505	COG4786	Flagellar basal body rod
GMB29_25510	COG4786	Flagellar basal body rod
GMB29_25515	COG1077	Cell shape determining protein MreB Mrl
GMB29_25520	COG1609	Transcriptional regulator
GMB29_25525	COG0739	heme binding
GMB29_25535	COG2385	sporulation resulting in formation of a cellular spore
GMB29_25540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GMB29_25550	COG4836	Membrane
GMB29_25555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GMB29_25560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GMB29_25565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GMB29_25570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GMB29_25575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GMB29_25580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GMB29_25590	COG0356	it plays a direct role in the translocation of protons across the membrane
GMB29_25605	COG1404	Belongs to the peptidase S8 family
GMB29_25610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GMB29_25615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GMB29_25625	COG0698	ribose 5-phosphate isomerase
GMB29_25630	COG0840	transmembrane signaling receptor activity
GMB29_25645	COG0701	Predicted permease
GMB29_25650	COG1785	Belongs to the alkaline phosphatase family
GMB29_25655	COG0523	cobalamin synthesis protein
GMB29_25665	COG1971	Probably functions as a manganese efflux pump
GMB29_25670	COG0009	L-threonylcarbamoyladenylate synthase
GMB29_25675	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GMB29_25690	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GMB29_25695	COG0346	lactoylglutathione lyase activity
GMB29_25700	COG0789	Transcriptional regulator
GMB29_25705	COG1435	thymidine kinase activity
GMB29_25715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GMB29_25720	COG1494	fructose-1,6-bisphosphatase
GMB29_25725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GMB29_25730	COG0191	fructose-bisphosphate aldolase activity
GMB29_25735	COG2204	response regulator
GMB29_25740	COG4821	SIS domain
GMB29_25745	COG0504	CTP synthase activity
GMB29_25750	COG3343	RNA polymerase activity
GMB29_25755	COG1703	isobutyryl-CoA mutase activity
GMB29_25755	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMB29_25755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMB29_25765	COG1960	acyl-CoA dehydrogenase activity
GMB29_25770	COG1960	acyl-CoA dehydrogenase activity
GMB29_25775	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMB29_25780	COG0183	Belongs to the thiolase family
GMB29_25785	COG2181	nitrate reductase activity
GMB29_25785	COG0247	lactate metabolic process
GMB29_25790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMB29_25795	COG0018	arginyl-trna synthetase
GMB29_25800	COG4506	Protein conserved in bacteria
GMB29_25805	COG2340	Cysteine-rich secretory protein family
GMB29_25810	COG0010	Belongs to the arginase family
GMB29_25815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GMB29_25820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GMB29_25830	COG1994	Peptidase M50
GMB29_25840	COG3465	dGTPase activity
GMB29_25845	COG1078	dGTPase activity
GMB29_25855	COG2217	Heavy metal translocating P-type atpase
GMB29_25870	COG0280	phosphate acetyltransferase
GMB29_25890	COG2363	Small membrane protein
GMB29_25900	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GMB29_25915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GMB29_25930	COG0778	Nitroreductase
GMB29_25935	COG0477	Major facilitator Superfamily
GMB29_25950	COG0483	inositol monophosphate 1-phosphatase activity
GMB29_25960	COG1178	ABC-type Fe3 transport system permease component
GMB29_25965	COG3842	ATPase activity
GMB29_25970	COG1840	ABC-type Fe3 transport system, periplasmic component
GMB29_25975	COG0584	glycerophosphoryl diester phosphodiesterase
GMB29_25990	COG0346	lactoylglutathione lyase activity
GMB29_25995	COG0551	DNA topoisomerase type I activity
GMB29_25995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GMB29_26000	COG0488	(ABC) transporter
GMB29_26010	COG1366	Belongs to the anti-sigma-factor antagonist family
GMB29_26015	COG2197	response regulator
GMB29_26040	COG0723	plastoquinol--plastocyanin reductase activity
GMB29_26040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMB29_26050	COG2514	catechol 2,3-dioxygenase activity
GMB29_26060	COG1587	Uroporphyrinogen-III synthase
GMB29_26060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GMB29_26065	COG2146	nitrite reductase [NAD(P)H] activity
GMB29_26070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMB29_26075	COG0243	molybdopterin cofactor binding
GMB29_26080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMB29_26085	COG2223	nitrite transmembrane transporter activity
GMB29_26090	COG1846	Transcriptional regulator
GMB29_26095	COG2814	Major facilitator Superfamily
GMB29_26100	COG1587	Uroporphyrinogen-III synthase
GMB29_26105	COG0788	formyltetrahydrofolate deformylase activity
GMB29_26115	COG2966	Psort location CytoplasmicMembrane, score
GMB29_26120	COG0653	protein targeting
GMB29_26125	COG1263	PTS System
GMB29_26125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GMB29_26130	COG0366	Alpha amylase catalytic
GMB29_26135	COG2188	Transcriptional regulator
GMB29_26140	COG2195	Cleaves the N-terminal amino acid of tripeptides
GMB29_26170	COG5444	nuclease activity
GMB29_26190	COG1511	domain protein
GMB29_26195	COG1674	ftsk spoiiie
GMB29_26195	COG0433	COG0433 Predicted ATPase
GMB29_26200	COG4499	WXG100 protein secretion system (Wss), protein YukC
GMB29_26205	COG5417	Belongs to the EsaB family
GMB29_26210	COG4842	Belongs to the WXG100 family
GMB29_26230	COG2270	Major facilitator Superfamily
GMB29_26235	COG1132	(ABC) transporter
GMB29_26240	COG1132	(ABC) transporter
GMB29_26260	COG3104	oligopeptide transport
GMB29_26270	COG1131	(ABC) transporter
GMB29_26285	COG1595	DNA-templated transcription, initiation
GMB29_26295	COG0411	ABC transporter
GMB29_26305	COG0559	Belongs to the binding-protein-dependent transport system permease family
GMB29_26315	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GMB29_26320	COG3842	ATPase activity
GMB29_26325	COG1176	ABC-type spermidine putrescine transport system, permease component I
GMB29_26330	COG1176	ABC-type spermidine putrescine transport system, permease component I
GMB29_26350	COG2211	Major facilitator Superfamily
GMB29_26360	COG2814	Major facilitator Superfamily
GMB29_26390	COG1349	DNA-binding transcription factor activity
GMB29_26395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GMB29_26400	COG2011	ABC-type metal ion transport system permease component
GMB29_26405	COG1464	Belongs to the NlpA lipoprotein family
GMB29_26415	COG0640	Transcriptional regulator
GMB29_26455	COG1126	abc transporter atp-binding protein
GMB29_26460	COG0765	amino acid transport
GMB29_26470	COG0745	RESPONSE REGULATOR receiver
GMB29_26475	COG2205	protein histidine kinase activity
GMB29_26480	COG1136	(ABC) transporter
GMB29_26485	COG0577	efflux transmembrane transporter activity
GMB29_26490	COG1902	pentaerythritol trinitrate reductase activity
GMB29_26495	COG2824	Alkylphosphonate utilization operon protein PhnA
GMB29_26500	COG3403	YqcI/YcgG family
GMB29_26505	COG1834	amidinotransferase
GMB29_26510	COG5577	PFAM Coat F domain
GMB29_26515	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GMB29_26520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GMB29_26540	COG4191	Histidine kinase
GMB29_26550	COG4191	Histidine kinase
GMB29_26560	COG3973	AAA domain
GMB29_26570	COG1695	Transcriptional regulator
GMB29_26575	COG0450	alkyl hydroperoxide reductase
GMB29_26595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GMB29_26600	COG3706	GGDEF domain
GMB29_26600	COG0745	RESPONSE REGULATOR receiver
GMB29_26605	COG0673	inositol 2-dehydrogenase activity
GMB29_26620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GMB29_26625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GMB29_26630	COG2169	Transcriptional regulator
GMB29_26650	COG0778	Nitroreductase
GMB29_26655	COG1309	transcriptional regulator
GMB29_26660	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GMB29_26670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMB29_26675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GMB29_26680	COG4853	Protein conserved in bacteria
GMB29_26685	COG4863	YycH protein
GMB29_26690	COG5002	protein histidine kinase activity
GMB29_26695	COG0745	RESPONSE REGULATOR receiver
GMB29_26700	COG1196	nuclear chromosome segregation
GMB29_26700	COG0741	lytic transglycosylase activity
GMB29_26700	COG0739	heme binding
GMB29_26725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GMB29_26730	COG0305	Participates in initiation and elongation during chromosome replication
GMB29_26735	COG0359	binds to the 23S rRNA
GMB29_26740	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GMB29_26745	COG4241	membrane
GMB29_26750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GMB29_26755	COG0629	single-stranded DNA binding
GMB29_26765	COG0012	GTP binding
GMB29_26770	COG0243	molybdopterin cofactor binding
GMB29_26775	COG4481	Protein conserved in bacteria
GMB29_26780	COG0668	transmembrane transport
GMB29_26785	COG3949	Membrane
GMB29_26795	COG1811	Na channel or pump
GMB29_26800	COG1475	DNA binding
GMB29_26805	COG1192	Involved in chromosome partitioning
GMB29_26810	COG1475	DNA binding
GMB29_26820	COG0445	tRNA wobble uridine modification
GMB29_26825	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMB29_26830	COG1847	R3H domain protein
GMB29_26835	COG0706	membrane insertase activity
GMB29_26840	COG0594	ribonuclease P activity