locus-tag	class	description
AZK53_00075	COG1982	Orn Lys Arg decarboxylase major
AZK53_00080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AZK53_00085	COG3870	Protein conserved in bacteria
AZK53_00090	COG0470	DNA polymerase III
AZK53_00095	COG1774	PSP1 C-terminal conserved region
AZK53_00100	COG4467	Involved in initiation control of chromosome replication
AZK53_00105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AZK53_00110	COG2827	Endonuclease containing a URI domain
AZK53_00115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AZK53_00120	COG2002	toxin-antitoxin pair type II binding
AZK53_00130	COG0084	hydrolase, TatD family'
AZK53_00140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AZK53_00150	COG4466	Protein conserved in bacteria
AZK53_00165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZK53_00170	COG0251	oxidation-reduction process
AZK53_00175	COG2088	sporulation resulting in formation of a cellular spore
AZK53_00180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AZK53_00185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AZK53_00190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AZK53_00195	COG0193	aminoacyl-tRNA hydrolase activity
AZK53_00205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AZK53_00210	COG2002	toxin-antitoxin pair type II binding
AZK53_00215	COG2244	polysaccharide biosynthetic process
AZK53_00220	COG3956	TIGRFAM MazG family protein
AZK53_00225	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AZK53_00240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AZK53_00245	COG1098	S1 RNA binding domain
AZK53_00265	COG2304	oxidoreductase activity
AZK53_00270	COG0515	serine threonine protein kinase
AZK53_00275	COG0037	tRNA processing
AZK53_00285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AZK53_00290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AZK53_00295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AZK53_00300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZK53_00305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AZK53_00310	COG0512	Glutamine amidotransferase of anthranilate synthase
AZK53_00315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZK53_00320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AZK53_00325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZK53_00330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AZK53_00355	COG3880	PFAM UvrB UvrC protein
AZK53_00360	COG3869	Catalyzes the specific phosphorylation of arginine residues in
AZK53_00365	COG0542	response to heat
AZK53_00370	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AZK53_00375	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AZK53_00380	COG4956	integral membrane protein (PIN domain superfamily)
AZK53_00385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AZK53_00395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AZK53_00400	COG1045	serine acetyltransferase
AZK53_00405	COG0215	cysteine-tRNA ligase activity
AZK53_00415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZK53_00420	COG3688	RNA-binding protein containing a PIN domain
AZK53_00430	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AZK53_00435	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZK53_00440	COG0250	Participates in transcription elongation, termination and antitermination
AZK53_00450	COG0081	regulation of translation
AZK53_00455	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AZK53_00465	COG2813	Specifically methylates the guanine in position
AZK53_00470	COG0085	RNA polymerase activity
AZK53_00480	COG1358	cellular component organization or biogenesis
AZK53_00485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AZK53_00490	COG0049	tRNA binding
AZK53_00500	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AZK53_00505	COG0051	transcription antitermination factor activity, RNA binding
AZK53_00510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AZK53_00515	COG0088	Forms part of the polypeptide exit tunnel
AZK53_00520	COG0089	rRNA binding
AZK53_00525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZK53_00530	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AZK53_00535	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AZK53_00540	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AZK53_00545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AZK53_00550	COG0255	Belongs to the universal ribosomal protein uL29 family
AZK53_00555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AZK53_00560	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AZK53_00575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZK53_00595	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AZK53_00600	COG1841	ribosomal large subunit assembly
AZK53_00610	COG0201	protein transport
AZK53_00615	COG0563	adenylate kinase activity
AZK53_00620	COG0024	Methionine aminopeptidase
AZK53_00625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AZK53_00630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AZK53_00635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZK53_00645	COG0202	RNA polymerase activity
AZK53_00650	COG0203	ribosomal protein L17
AZK53_00655	COG1122	ATPase activity
AZK53_00660	COG1122	ATPase activity
AZK53_00665	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AZK53_00670	COG0101	tRNA pseudouridine synthase activity
AZK53_00675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AZK53_00690	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_00695	COG0489	protein tyrosine kinase activity
AZK53_00700	COG0583	DNA-binding transcription factor activity
AZK53_00710	COG2194	sulfuric ester hydrolase activity
AZK53_00715	COG0726	polysaccharide deacetylase
AZK53_00790	COG1595	DNA-templated transcription, initiation
AZK53_00795	COG5662	AntiSigma factor
AZK53_00800	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AZK53_00810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZK53_00815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AZK53_00825	COG0791	NLP P60 protein
AZK53_00825	COG1388	LysM domain
AZK53_00825	COG3103	Sh3 type 3 domain protein
AZK53_00830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_00830	COG2213	PTS system mannitol-specific
AZK53_00835	COG3711	transcriptional antiterminator
AZK53_00840	COG0246	Mannitol dehydrogenase
AZK53_00850	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_00855	COG1970	mechanosensitive ion channel activity
AZK53_00860	COG1368	sulfuric ester hydrolase activity
AZK53_00875	COG1176	ABC-type spermidine putrescine transport system, permease component I
AZK53_00880	COG1177	transmembrane transport
AZK53_00885	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AZK53_00895	COG0745	RESPONSE REGULATOR receiver
AZK53_00900	COG5002	protein histidine kinase activity
AZK53_00915	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AZK53_00915	COG3976	FMN-binding domain protein
AZK53_00920	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZK53_00925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZK53_00930	COG0513	Belongs to the DEAD box helicase family
AZK53_00935	COG4294	response to UV
AZK53_00940	COG0705	Rhomboid family
AZK53_00945	COG0736	holo-[acyl-carrier-protein] synthase activity
AZK53_00950	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AZK53_00955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AZK53_00960	COG0864	Transcriptional regulator
AZK53_00965	COG2337	Toxic component of a toxin-antitoxin (TA) module
AZK53_00970	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_00975	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_00980	COG2172	sigma factor antagonist activity
AZK53_00985	COG2208	phosphoserine phosphatase activity
AZK53_00990	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_01000	COG1191	sigma factor activity
AZK53_01005	COG2208	phosphoserine phosphatase activity
AZK53_01010	COG2183	response to ionizing radiation
AZK53_01100	COG0802	atpase or kinase
AZK53_01105	COG1214	PFAM Peptidase M22, glycoprotease
AZK53_01110	COG0456	acetyltransferase
AZK53_01120	COG0488	(ABC) transporter
AZK53_01125	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AZK53_01130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_01135	COG0805	protein transport
AZK53_01145	COG1266	CAAX protease self-immunity
AZK53_01150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AZK53_01160	COG0714	Associated with various cellular activities
AZK53_01165	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
AZK53_01170	COG1305	Transglutaminase-like
AZK53_01175	COG0519	Catalyzes the synthesis of GMP from XMP
AZK53_01175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AZK53_01180	COG2252	PERMEase
AZK53_01235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AZK53_01240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AZK53_01245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AZK53_01250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AZK53_01255	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZK53_01260	COG0047	phosphoribosylformylglycinamidine synthase activity
AZK53_01265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AZK53_01270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AZK53_01275	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AZK53_01280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AZK53_01285	COG0138	bifunctional purine biosynthesis protein purh
AZK53_01290	COG0151	Belongs to the GarS family
AZK53_01300	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZK53_01305	COG4496	protein, YerC YecD
AZK53_01310	COG0423	glycine-tRNA ligase activity
AZK53_01320	COG0210	DNA helicase
AZK53_01330	COG4851	CamS sex pheromone cAM373 precursor
AZK53_01340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AZK53_01345	COG0154	amidase activity
AZK53_01355	COG1597	lipid kinase activity
AZK53_01365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_01375	COG0166	Belongs to the GPI family
AZK53_01380	COG1744	ABC transporter substrate-binding protein PnrA-like
AZK53_01385	COG3852	Histidine kinase
AZK53_01390	COG0024	Methionine aminopeptidase
AZK53_01395	COG2706	6-phosphogluconolactonase activity
AZK53_01405	COG0789	Transcriptional regulator
AZK53_01405	COG4978	Transcriptional regulator
AZK53_01410	COG2814	Major facilitator Superfamily
AZK53_01420	COG1876	peptidase activity
AZK53_01425	COG1126	abc transporter atp-binding protein
AZK53_01430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_01435	COG0765	amino acid transport
AZK53_01440	COG0765	amino acid transport
AZK53_01445	COG1113	amino acid transport
AZK53_01450	COG2733	membrane
AZK53_01455	COG3212	peptidase
AZK53_01460	COG3212	peptidase
AZK53_01465	COG3850	Histidine kinase
AZK53_01465	COG5002	protein histidine kinase activity
AZK53_01470	COG0745	RESPONSE REGULATOR receiver
AZK53_01475	COG0671	phosphoesterase, PA-phosphatase related
AZK53_01480	COG1764	response to oxidative stress
AZK53_01485	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AZK53_01495	COG2259	Doxx family
AZK53_01500	COG0693	protein deglycase activity
AZK53_01510	COG2318	DinB family
AZK53_01520	COG1115	amino acid carrier protein
AZK53_01535	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
AZK53_01540	COG0598	Magnesium transport protein CorA
AZK53_01545	COG3290	protein histidine kinase activity
AZK53_01550	COG4565	transcriptional regulatory protein
AZK53_01565	COG4191	Histidine kinase
AZK53_01570	COG0513	Belongs to the DEAD box helicase family
AZK53_01590	COG4842	Belongs to the WXG100 family
AZK53_01595	COG5417	Belongs to the EsaB family
AZK53_01600	COG4499	WXG100 protein secretion system (Wss), protein YukC
AZK53_01605	COG1674	ftsk spoiiie
AZK53_01605	COG0433	COG0433 Predicted ATPase
AZK53_01610	COG1511	domain protein
AZK53_01625	COG2356	endonuclease I
AZK53_01635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_01650	COG0488	(ABC) transporter
AZK53_01655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_01660	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AZK53_01670	COG1959	2 iron, 2 sulfur cluster binding
AZK53_01675	COG1017	nitric oxide dioxygenase activity
AZK53_01675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AZK53_01685	COG0693	protein deglycase activity
AZK53_01690	COG2340	Cysteine-rich secretory protein family
AZK53_01695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AZK53_01700	COG4840	Belongs to the UPF0435 family
AZK53_01705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AZK53_01710	COG4980	gas vesicle protein
AZK53_01715	COG1295	ribonuclease BN
AZK53_01720	COG2217	Heavy metal translocating P-type atpase
AZK53_01730	COG0640	Transcriptional regulator
AZK53_01740	COG0477	Major facilitator Superfamily
AZK53_01745	COG3479	Phenolic acid decarboxylase
AZK53_01755	COG3871	stress protein (general stress protein 26)
AZK53_01760	COG0387	Pfam Sodium calcium exchanger
AZK53_01770	COG0535	radical SAM domain protein
AZK53_01790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZK53_01800	COG1113	amino acid transport
AZK53_01805	COG5002	protein histidine kinase activity
AZK53_01820	COG1090	epimerase
AZK53_01830	COG4221	oxidoreductase activity
AZK53_01850	COG1988	membrane-bound metal-dependent
AZK53_01855	COG1194	a g-specific adenine glycosylase
AZK53_01865	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_01880	COG3557	Belongs to the UPF0374 family
AZK53_01885	COG1132	(ABC) transporter
AZK53_01890	COG4129	membrane
AZK53_01895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZK53_01900	COG4555	ABC transporter
AZK53_01920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZK53_01925	COG0735	belongs to the Fur family
AZK53_02040	COG3382	B3 4 domain protein
AZK53_02055	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AZK53_02060	COG2766	serine protein kinase
AZK53_02075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZK53_02090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AZK53_02100	COG1968	undecaprenyl-diphosphatase activity
AZK53_02105	COG1301	dicarboxylic acid transport
AZK53_02115	COG0586	Pfam SNARE associated Golgi protein
AZK53_02120	COG2217	Heavy metal translocating P-type atpase
AZK53_02125	COG0531	amino acid
AZK53_02145	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AZK53_02155	COG1175	transmembrane transport
AZK53_02165	COG1653	transport
AZK53_02170	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_02190	COG4948	Mandelate Racemase Muconate Lactonizing
AZK53_02235	COG3583	domain protein
AZK53_02235	COG3584	3D domain protein
AZK53_02240	COG1876	peptidase activity
AZK53_02245	COG3103	Sh3 type 3 domain protein
AZK53_02250	COG0456	acetyltransferase
AZK53_02250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_02260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_02280	COG1609	Transcriptional regulator
AZK53_02285	COG2814	Major facilitator Superfamily
AZK53_02290	COG0673	inositol 2-dehydrogenase activity
AZK53_02315	COG1609	Transcriptional regulator
AZK53_02330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_02335	COG1522	sequence-specific DNA binding
AZK53_02350	COG2814	Major facilitator Superfamily
AZK53_02355	COG1309	transcriptional regulator
AZK53_02360	COG1187	pseudouridine synthase activity
AZK53_02370	COG1942	4-Oxalocrotonate Tautomerase
AZK53_02375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZK53_02380	COG0747	negative chemotaxis
AZK53_02395	COG0084	hydrolase, TatD family'
AZK53_02400	COG2962	Rard protein
AZK53_02410	COG0628	permease
AZK53_02425	COG0604	alcohol dehydrogenase
AZK53_02430	COG1620	l-lactate permease
AZK53_02440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZK53_02445	COG0840	transmembrane signaling receptor activity
AZK53_02450	COG0564	pseudouridine synthase activity
AZK53_02460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZK53_02465	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_02470	COG3153	acetyltransferase
AZK53_02470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_02475	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AZK53_02480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AZK53_02490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AZK53_02495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AZK53_02500	COG1268	BioY protein
AZK53_02510	COG2719	SpoVR family
AZK53_02520	COG1959	2 iron, 2 sulfur cluster binding
AZK53_02525	COG0604	alcohol dehydrogenase
AZK53_02535	COG1126	abc transporter atp-binding protein
AZK53_02540	COG0765	amino acid transport
AZK53_02545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_02550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZK53_02555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AZK53_02565	COG0352	thiamine-phosphate diphosphorylase activity
AZK53_02570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_02585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZK53_02590	COG0351	phosphomethylpyrimidine kinase
AZK53_02605	COG0702	epimerase
AZK53_02610	COG1253	flavin adenine dinucleotide binding
AZK53_02625	COG3842	ATPase activity
AZK53_02630	COG2508	Transcriptional regulator
AZK53_02645	COG0189	ligase activity
AZK53_02650	COG0189	ligase activity
AZK53_02660	COG3679	Belongs to the UPF0342 family
AZK53_02665	COG0561	phosphatase activity
AZK53_02670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZK53_02675	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_02680	COG1024	Enoyl-CoA hydratase
AZK53_02695	COG4152	abc transporter atp-binding protein
AZK53_02700	COG1668	transmembrane transport
AZK53_02705	COG3481	metal-dependent phosphohydrolase, HD sub domain
AZK53_02715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZK53_02730	COG1846	Transcriptional regulator
AZK53_02745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AZK53_02750	COG1695	Transcriptional regulator
AZK53_02755	COG2153	protein acetylation
AZK53_02760	COG2755	lipolytic protein G-D-S-L family
AZK53_02760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AZK53_02765	COG0537	adenosine 5'-monophosphoramidase activity
AZK53_02770	COG1131	(ABC) transporter
AZK53_02775	COG4473	ABC transporter
AZK53_02785	COG1473	amidohydrolase
AZK53_02790	COG0671	phosphoesterase, PA-phosphatase related
AZK53_02795	COG3069	C4-dicarboxylate transmembrane transporter activity
AZK53_02800	COG2329	Antibiotic biosynthesis monooxygenase
AZK53_02805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_02810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AZK53_02825	COG1309	transcriptional regulator
AZK53_02840	COG2972	Histidine kinase
AZK53_02850	COG1234	tRNA 3'-trailer cleavage
AZK53_02855	COG0095	Lipoate-protein ligase
AZK53_02860	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_02865	COG1024	Enoyl-CoA hydratase
AZK53_02980	COG0501	Belongs to the peptidase M48B family
AZK53_02985	COG2224	Isocitrate lyase
AZK53_02995	COG0823	Involved in the tonB-independent uptake of proteins
AZK53_02995	COG4946	Tricorn protease homolog
AZK53_02995	COG1506	peptidase
AZK53_03000	COG0398	Pfam SNARE associated Golgi protein
AZK53_03005	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_03010	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AZK53_03015	COG1074	ATP-dependent DNA helicase activity
AZK53_03020	COG0420	3'-5' exonuclease activity
AZK53_03025	COG0419	ATPase involved in DNA repair
AZK53_03030	COG1403	HNH endonuclease
AZK53_03065	COG2311	Membrane
AZK53_03080	COG0367	asparagine synthase
AZK53_03095	COG1562	ergosterol biosynthetic process
AZK53_03105	COG1874	Beta-galactosidase
AZK53_03105	COG0366	Alpha amylase catalytic
AZK53_03110	COG1609	Transcriptional regulator
AZK53_03115	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_03120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AZK53_03125	COG4187	Peptidase family M20/M25/M40
AZK53_03130	COG0833	amino acid
AZK53_03135	COG3829	transcription factor binding
AZK53_03140	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_03145	COG1666	GTP binding
AZK53_03150	COG2996	Protein conserved in bacteria
AZK53_03155	COG1307	EDD domain protein, DegV family
AZK53_03160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_03170	COG0561	phosphatase activity
AZK53_03175	COG2151	metal-sulfur cluster biosynthetic enzyme
AZK53_03180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZK53_03185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AZK53_03190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AZK53_03195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AZK53_03215	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AZK53_03230	COG0542	response to heat
AZK53_03245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AZK53_03250	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AZK53_03255	COG2084	Dehydrogenase
AZK53_03265	COG2267	carboxylic ester hydrolase activity
AZK53_03285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZK53_03290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AZK53_03295	COG5504	Zn-dependent protease
AZK53_03300	COG0444	Belongs to the ABC transporter superfamily
AZK53_03305	COG4608	Belongs to the ABC transporter superfamily
AZK53_03315	COG0601	transmembrane transport
AZK53_03330	COG0180	Tryptophanyl-tRNA synthetase
AZK53_03340	COG4166	transmembrane transport
AZK53_03345	COG0601	transmembrane transport
AZK53_03350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_03355	COG0444	Belongs to the ABC transporter superfamily
AZK53_03360	COG4608	Belongs to the ABC transporter superfamily
AZK53_03365	COG0456	acetyltransferase
AZK53_03370	COG1113	amino acid transport
AZK53_03375	COG0531	amino acid
AZK53_03380	COG1393	Belongs to the ArsC family
AZK53_03385	COG0583	DNA-binding transcription factor activity
AZK53_03400	COG0861	Integral membrane protein TerC family
AZK53_03410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_03420	COG1164	Oligoendopeptidase f
AZK53_03435	COG2346	COG2346, Truncated hemoglobins
AZK53_03440	COG0741	lytic transglycosylase activity
AZK53_03445	COG4116	CYTH
AZK53_03455	COG2357	RelA SpoT domain protein
AZK53_03460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZK53_03465	COG0564	pseudouridine synthase activity
AZK53_03475	COG2239	Acts as a magnesium transporter
AZK53_03480	COG0569	domain protein
AZK53_03480	COG0475	glutathione-regulated potassium exporter activity
AZK53_03525	COG0210	DNA helicase
AZK53_03535	COG2323	membrane
AZK53_03540	COG2153	protein acetylation
AZK53_03550	COG2382	esterase
AZK53_03560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZK53_03570	COG1737	Transcriptional regulator
AZK53_03575	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AZK53_03580	COG1070	Carbohydrate kinase
AZK53_03585	COG1953	Uracil, thiamine, allantoin
AZK53_03605	COG1522	sequence-specific DNA binding
AZK53_03615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZK53_03630	COG3142	Participates in the control of copper homeostasis
AZK53_03635	COG1113	amino acid transport
AZK53_03645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_03650	COG1309	transcriptional regulator
AZK53_03655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_03655	COG3711	transcriptional antiterminator
AZK53_03660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZK53_03665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AZK53_03670	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZK53_03675	COG1486	melibiose metabolic process
AZK53_03680	COG3275	phosphorelay sensor kinase activity
AZK53_03685	COG3279	Response regulator of the LytR AlgR family
AZK53_03695	COG1346	cytolysis
AZK53_03705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZK53_03710	COG0243	molybdopterin cofactor binding
AZK53_03715	COG2223	nitrite transmembrane transporter activity
AZK53_03735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AZK53_03760	COG3527	Alpha-acetolactate decarboxylase
AZK53_03765	COG0028	Belongs to the TPP enzyme family
AZK53_03770	COG4895	conserved protein (DUF2196)
AZK53_03780	COG1733	regulation of RNA biosynthetic process
AZK53_03785	COG2814	Major facilitator Superfamily
AZK53_03790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_03810	COG3052	prosthetic group binding
AZK53_03825	COG0784	Response regulator, receiver
AZK53_03830	COG4191	Histidine kinase
AZK53_03835	COG2066	Belongs to the glutaminase family
AZK53_03840	COG1115	amino acid carrier protein
AZK53_03845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_03855	COG4297	protein containing double-stranded beta helix domain
AZK53_03860	COG0531	amino acid
AZK53_03870	COG1607	acyl-coa hydrolase
AZK53_03875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AZK53_03890	COG0390	transport system, permease component
AZK53_03895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AZK53_03910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AZK53_03915	COG1136	(ABC) transporter
AZK53_03920	COG0577	efflux transmembrane transporter activity
AZK53_03930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AZK53_03950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZK53_03955	COG0833	amino acid
AZK53_03965	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AZK53_03970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_03980	COG0861	Integral membrane protein TerC family
AZK53_03985	COG1301	dicarboxylic acid transport
AZK53_03990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AZK53_03995	COG3290	protein histidine kinase activity
AZK53_04035	COG1476	TRANSCRIPTIONal
AZK53_04045	COG1368	sulfuric ester hydrolase activity
AZK53_04060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_04065	COG2040	homocysteine
AZK53_04070	COG0179	Fumarylacetoacetate (FAA) hydrolase
AZK53_04085	COG2851	Citrate transporter
AZK53_04090	COG3290	protein histidine kinase activity
AZK53_04095	COG4565	transcriptional regulatory protein
AZK53_04100	COG3181	Tripartite tricarboxylate transporter family receptor
AZK53_04105	COG0583	DNA-binding transcription factor activity
AZK53_04110	COG3180	Ammonia monooxygenase
AZK53_04115	COG2226	methyltransferase
AZK53_04125	COG4175	Glycine betaine
AZK53_04125	COG0517	IMP dehydrogenase activity
AZK53_04130	COG2113	Glycine betaine
AZK53_04135	COG1309	transcriptional regulator
AZK53_04155	COG0531	amino acid
AZK53_04160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZK53_04165	COG1464	Belongs to the NlpA lipoprotein family
AZK53_04170	COG2011	ABC-type metal ion transport system permease component
AZK53_04175	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_04190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_04200	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AZK53_04205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_04210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_04235	COG1737	Transcriptional regulator
AZK53_04240	COG1263	PTS System
AZK53_04240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_04250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_04255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZK53_04260	COG1116	anion transmembrane transporter activity
AZK53_04265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_04270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZK53_04280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AZK53_04285	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AZK53_04290	COG1733	regulation of RNA biosynthetic process
AZK53_04325	COG1511	domain protein
AZK53_04335	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZK53_04340	COG1733	regulation of RNA biosynthetic process
AZK53_04350	COG1132	(ABC) transporter
AZK53_04355	COG1132	(ABC) transporter
AZK53_04365	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_04370	COG3162	membrane
AZK53_04380	COG1414	Transcriptional regulator
AZK53_04385	COG0656	L-ascorbic acid biosynthetic process
AZK53_04390	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AZK53_04395	COG1846	Transcriptional regulator
AZK53_04400	COG1566	PFAM secretion protein HlyD family protein
AZK53_04405	COG2814	Major facilitator Superfamily
AZK53_04410	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZK53_04425	COG1609	Transcriptional regulator
AZK53_04430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_04440	COG1129	ABC transporter
AZK53_04445	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZK53_04450	COG1879	ABC-type sugar transport system periplasmic component
AZK53_04455	COG3583	domain protein
AZK53_04455	COG3584	3D domain protein
AZK53_04460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AZK53_04465	COG1653	transport
AZK53_04490	COG3706	GGDEF domain
AZK53_04490	COG0745	RESPONSE REGULATOR receiver
AZK53_04510	COG0745	RESPONSE REGULATOR receiver
AZK53_04515	COG5002	protein histidine kinase activity
AZK53_04550	COG0402	S-adenosylhomocysteine deaminase activity
AZK53_04555	COG2252	PERMEase
AZK53_04565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZK53_04570	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_04580	COG0710	3-dehydroquinate dehydratase activity
AZK53_04585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_04585	COG1263	PTS System
AZK53_04590	COG0366	Alpha amylase catalytic
AZK53_04595	COG2188	Transcriptional regulator
AZK53_04605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_04610	COG1984	allophanate hydrolase subunit 2
AZK53_04615	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_04620	COG1914	H( )-stimulated, divalent metal cation uptake system
AZK53_04625	COG1272	protein, Hemolysin III
AZK53_04640	COG0778	Nitroreductase
AZK53_04645	COG0628	permease
AZK53_04665	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZK53_04670	COG2271	Major facilitator Superfamily
AZK53_04675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AZK53_04680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZK53_04685	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_04695	COG0402	S-adenosylhomocysteine deaminase activity
AZK53_04700	COG1278	Cold shock
AZK53_04705	COG2910	NAD(P)H-binding
AZK53_04710	COG0673	inositol 2-dehydrogenase activity
AZK53_04715	COG0450	alkyl hydroperoxide reductase
AZK53_04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_04735	COG3706	GGDEF domain
AZK53_04735	COG4251	negative regulation of phosphorylation
AZK53_04735	COG2203	Gaf domain
AZK53_04735	COG5001	Diguanylate cyclase
AZK53_04740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_04745	COG2076	Multidrug Resistance protein
AZK53_04750	COG2076	Multidrug Resistance protein
AZK53_04820	COG1649	PFAM Uncharacterised BCR, COG1649
AZK53_04825	COG1737	Transcriptional regulator
AZK53_04845	COG1486	melibiose metabolic process
AZK53_04855	COG1447	Phosphotransferase system cellobiose-specific component IIA
AZK53_04865	COG2971	BadF BadG BcrA BcrD
AZK53_04870	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AZK53_04885	COG3037	sugar-specific permease SgaT UlaA
AZK53_04890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZK53_04890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_04900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AZK53_04915	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_04920	COG4106	trans-aconitate 2-methyltransferase activity
AZK53_04925	COG0583	DNA-binding transcription factor activity
AZK53_04935	COG0667	Aldo Keto reductase
AZK53_04950	COG0154	amidase activity
AZK53_04960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AZK53_04995	COG2200	EAL domain
AZK53_04995	COG2199	diguanylate cyclase activity
AZK53_05005	COG1733	regulation of RNA biosynthetic process
AZK53_05020	COG0385	Bile acid
AZK53_05030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_05035	COG4191	Histidine kinase
AZK53_05040	COG0784	Response regulator, receiver
AZK53_05055	COG0791	NLP P60 protein
AZK53_05055	COG1388	LysM domain
AZK53_05065	COG2385	sporulation resulting in formation of a cellular spore
AZK53_05070	COG0656	L-ascorbic acid biosynthetic process
AZK53_05080	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZK53_05085	COG4948	Mandelate Racemase Muconate Lactonizing
AZK53_05120	COG0477	Major facilitator Superfamily
AZK53_05125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZK53_05135	COG0640	Transcriptional regulator
AZK53_05140	COG5658	integral membrane protein
AZK53_05160	COG5001	Diguanylate cyclase
AZK53_05160	COG3300	MHYT domain
AZK53_05165	COG0302	gtp cyclohydrolase
AZK53_05180	COG5001	Diguanylate cyclase
AZK53_05180	COG3300	MHYT domain
AZK53_05185	COG0531	amino acid
AZK53_05200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZK53_05235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZK53_05240	COG1396	sequence-specific DNA binding
AZK53_05260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZK53_05280	COG1215	transferase activity, transferring glycosyl groups
AZK53_05300	COG2247	cell wall binding repeat
AZK53_05300	COG2385	sporulation resulting in formation of a cellular spore
AZK53_05300	COG2247	cell wall binding repeat
AZK53_05300	COG2385	sporulation resulting in formation of a cellular spore
AZK53_05315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_05320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AZK53_05325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZK53_05330	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AZK53_05335	COG0728	peptidoglycan biosynthetic process
AZK53_05340	COG0438	transferase activity, transferring glycosyl groups
AZK53_05365	COG0110	maltose O-acetyltransferase activity
AZK53_05375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AZK53_05390	COG1482	cell wall glycoprotein biosynthetic process
AZK53_05395	COG3944	biosynthesis protein
AZK53_05400	COG0489	protein tyrosine kinase activity
AZK53_05425	COG4464	protein tyrosine phosphatase activity
AZK53_05430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZK53_05435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_05465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AZK53_05470	COG1682	transport, permease protein
AZK53_05475	COG1134	teichoic acid transport
AZK53_05485	COG1316	TRANSCRIPTIONal
AZK53_05510	COG0028	Belongs to the TPP enzyme family
AZK53_05515	COG0069	glutamate synthase activity
AZK53_05525	COG2084	Dehydrogenase
AZK53_05560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZK53_05565	COG2146	nitrite reductase [NAD(P)H] activity
AZK53_05575	COG2116	formate transmembrane transporter activity
AZK53_05585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_05590	COG4975	Glucose uptake
AZK53_05605	COG0534	Mate efflux family protein
AZK53_05615	COG1316	TRANSCRIPTIONal
AZK53_05625	COG0598	Magnesium transport protein CorA
AZK53_05630	COG1404	Belongs to the peptidase S8 family
AZK53_05650	COG4821	SIS domain
AZK53_05660	COG0363	glucosamine-6-phosphate deaminase activity
AZK53_05665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZK53_05670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_05670	COG1263	PTS System
AZK53_05670	COG2190	(PTS) system
AZK53_05675	COG1811	Na channel or pump
AZK53_05680	COG3961	Belongs to the TPP enzyme family
AZK53_05715	COG1131	(ABC) transporter
AZK53_05720	COG1253	flavin adenine dinucleotide binding
AZK53_05725	COG0789	Transcriptional regulator
AZK53_05735	COG0346	lactoylglutathione lyase activity
AZK53_05740	COG2105	PFAM AIG2 family protein
AZK53_05740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
AZK53_05800	COG4187	Peptidase family M20/M25/M40
AZK53_05815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AZK53_05815	COG0456	acetyltransferase
AZK53_05830	COG2252	PERMEase
AZK53_05840	COG3279	Response regulator of the LytR AlgR family
AZK53_05845	COG4555	ABC transporter
AZK53_05850	COG1668	transmembrane transport
AZK53_05860	COG0789	Transcriptional regulator
AZK53_05865	COG1846	Transcriptional regulator
AZK53_05870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_05870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_05890	COG1785	Belongs to the alkaline phosphatase family
AZK53_05895	COG3279	Response regulator of the LytR AlgR family
AZK53_05900	COG0784	Response regulator, receiver
AZK53_05900	COG2205	protein histidine kinase activity
AZK53_05905	COG0861	Integral membrane protein TerC family
AZK53_05910	COG1191	sigma factor activity
AZK53_05940	COG3243	poly(R)-hydroxyalkanoic acid synthase
AZK53_05955	COG2186	Transcriptional regulator
AZK53_05960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZK53_05970	COG0247	lactate metabolic process
AZK53_05975	COG1139	Iron-sulfur cluster binding protein
AZK53_05980	COG1556	Lactate utilization protein
AZK53_05985	COG5002	protein histidine kinase activity
AZK53_05990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AZK53_05995	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AZK53_06000	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AZK53_06005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_06010	COG0436	Aminotransferase
AZK53_06015	COG1850	ribulose-bisphosphate carboxylase activity
AZK53_06020	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AZK53_06025	COG0235	Class ii aldolase
AZK53_06030	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AZK53_06040	COG1129	ABC transporter
AZK53_06045	COG1172	Belongs to the binding-protein-dependent transport system permease family
AZK53_06070	COG1846	Transcriptional regulator
AZK53_06080	COG2801	Transposase and inactivated derivatives
AZK53_06090	COG4191	Histidine kinase
AZK53_06100	COG0542	response to heat
AZK53_06115	COG0300	oxidoreductase activity
AZK53_06120	COG0697	spore germination
AZK53_06140	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AZK53_06145	COG0720	synthase
AZK53_06155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AZK53_06160	COG0702	epimerase
AZK53_06170	COG4873	Protein conserved in bacteria
AZK53_06190	COG3773	Cell wall hydrolase
AZK53_06230	COG1410	methionine synthase
AZK53_06230	COG0646	methionine synthase
AZK53_06235	COG0646	methionine synthase
AZK53_06235	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AZK53_06240	COG3949	Membrane
AZK53_06250	COG0307	riboflavin synthase, alpha
AZK53_06260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AZK53_06270	COG3711	transcriptional antiterminator
AZK53_06275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_06275	COG1263	PTS System
AZK53_06275	COG2190	(PTS) system
AZK53_06290	COG1346	cytolysis
AZK53_06300	COG0583	DNA-binding transcription factor activity
AZK53_06310	COG0456	acetyltransferase
AZK53_06315	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_06320	COG0778	Nitroreductase
AZK53_06325	COG0436	Aminotransferase
AZK53_06345	COG0784	Response regulator, receiver
AZK53_06345	COG0835	chemotaxis
AZK53_06355	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_06375	COG1408	metallophosphoesterase
AZK53_06380	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_06385	COG2200	EAL domain
AZK53_06400	COG4703	Protein of unknown function (DUF1797)
AZK53_06405	COG0517	IMP dehydrogenase activity
AZK53_06410	COG0583	DNA-binding transcription factor activity
AZK53_06415	COG2171	N-acyltransferase activity
AZK53_06420	COG1473	amidohydrolase
AZK53_06430	COG0668	transmembrane transport
AZK53_06435	COG0450	alkyl hydroperoxide reductase
AZK53_06440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_06445	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AZK53_06455	COG1132	(ABC) transporter
AZK53_06460	COG1132	(ABC) transporter
AZK53_06465	COG0569	domain protein
AZK53_06470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZK53_06480	COG0561	phosphatase activity
AZK53_06500	COG0022	dehydrogenase e1 component
AZK53_06505	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_06525	COG1982	Orn Lys Arg decarboxylase major
AZK53_06530	COG4476	Belongs to the UPF0223 family
AZK53_06535	COG4493	Belongs to the UPF0637 family
AZK53_06545	COG0483	inositol monophosphate 1-phosphatase activity
AZK53_06570	COG4896	Protein conserved in bacteria
AZK53_06585	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AZK53_06590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZK53_06595	COG4838	Belongs to the UPF0358 family
AZK53_06600	COG0772	Belongs to the SEDS family
AZK53_06605	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZK53_06610	COG1612	heme a metabolic process
AZK53_06615	COG0109	protoheme IX farnesyltransferase activity
AZK53_06640	COG3336	cytochrome c oxidase
AZK53_06650	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AZK53_06655	COG2340	Cysteine-rich secretory protein family
AZK53_06665	COG2738	Putative neutral zinc metallopeptidase
AZK53_06670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_06675	COG1694	Mazg nucleotide pyrophosphohydrolase
AZK53_06680	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AZK53_06685	COG1803	Methylglyoxal synthase
AZK53_06690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZK53_06695	COG0438	transferase activity, transferring glycosyl groups
AZK53_06700	COG0617	tRNA 3'-terminal CCA addition
AZK53_06705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AZK53_06705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AZK53_06715	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AZK53_06720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AZK53_06725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AZK53_06725	COG1199	ATP-dependent helicase activity
AZK53_06740	COG0436	Aminotransferase
AZK53_06745	COG0017	Asparaginyl-tRNA synthetase
AZK53_06750	COG3935	DnaD domain protein
AZK53_06755	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AZK53_06765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_06765	COG4499	WXG100 protein secretion system (Wss), protein YukC
AZK53_06770	COG3331	DNA recombination
AZK53_06805	COG5337	Spore coat protein CotH
AZK53_06820	COG0626	cystathionine gamma-synthase activity
AZK53_06825	COG0626	cystathionine gamma-synthase activity
AZK53_06840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_06850	COG1278	Cold shock
AZK53_06860	COG3706	GGDEF domain
AZK53_06870	COG1205	dead DEAH box helicase
AZK53_06870	COG1111	helicase
AZK53_06875	COG3359	exonuclease
AZK53_06885	COG4474	Belongs to the UPF0398 family
AZK53_06890	COG3599	regulation of cell shape
AZK53_06920	COG2197	response regulator
AZK53_06925	COG0366	Alpha amylase catalytic
AZK53_06930	COG0116	Belongs to the methyltransferase superfamily
AZK53_06945	COG1175	transmembrane transport
AZK53_06955	COG3842	ATPase activity
AZK53_06965	COG1199	ATP-dependent helicase activity
AZK53_06970	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AZK53_06975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZK53_06980	COG2233	PERMEase
AZK53_06985	COG0583	DNA-binding transcription factor activity
AZK53_06990	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_07000	COG3424	synthase
AZK53_07005	COG1755	Isoprenylcysteine carboxyl methyltransferase
AZK53_07010	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZK53_07015	COG3541	Predicted nucleotidyltransferase
AZK53_07040	COG0328	RNA-DNA hybrid ribonuclease activity
AZK53_07045	COG0328	RNA-DNA hybrid ribonuclease activity
AZK53_07070	COG2814	Major facilitator Superfamily
AZK53_07080	COG2233	PERMEase
AZK53_07085	COG2362	D-Aminopeptidase
AZK53_07090	COG0601	transmembrane transport
AZK53_07095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_07100	COG0444	Belongs to the ABC transporter superfamily
AZK53_07105	COG4166	transmembrane transport
AZK53_07110	COG1619	proteins homologs of microcin C7 resistance protein MccF
AZK53_07115	COG0791	NLP P60 protein
AZK53_07120	COG4608	Belongs to the ABC transporter superfamily
AZK53_07140	COG5001	Diguanylate cyclase
AZK53_07140	COG3300	MHYT domain
AZK53_07170	COG2197	response regulator
AZK53_07175	COG4585	Histidine kinase
AZK53_07180	COG3239	Fatty acid desaturase
AZK53_07185	COG2205	protein histidine kinase activity
AZK53_07195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_07210	COG1388	LysM domain
AZK53_07210	COG0791	NLP P60 protein
AZK53_07215	COG1819	glycosyl
AZK53_07220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_07235	COG2814	Major facilitator Superfamily
AZK53_07245	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_07250	COG3964	amidohydrolase
AZK53_07270	COG2188	Transcriptional regulator
AZK53_07280	COG0434	BtpA family
AZK53_07285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZK53_07295	COG1785	Belongs to the alkaline phosphatase family
AZK53_07300	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZK53_07305	COG1404	Belongs to the peptidase S8 family
AZK53_07315	COG1846	Transcriptional regulator
AZK53_07320	COG1566	PFAM secretion protein HlyD family protein
AZK53_07325	COG2814	Major facilitator Superfamily
AZK53_07330	COG1846	Transcriptional regulator
AZK53_07340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_07345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_07350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_07355	COG1120	ATPase activity
AZK53_07370	COG2814	Major facilitator Superfamily
AZK53_07390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_07395	COG1733	regulation of RNA biosynthetic process
AZK53_07400	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AZK53_07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_07420	COG4175	Glycine betaine
AZK53_07420	COG3448	diguanylate cyclase activity
AZK53_07425	COG4176	ABC-type proline glycine betaine transport system permease component
AZK53_07445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZK53_07450	COG2208	phosphoserine phosphatase activity
AZK53_07460	COG0531	amino acid
AZK53_07470	COG1011	Hydrolase
AZK53_07475	COG0405	Gamma-glutamyltransferase
AZK53_07480	COG1621	beta-fructofuranosidase activity
AZK53_07485	COG1621	beta-fructofuranosidase activity
AZK53_07490	COG2193	ferroxidase activity
AZK53_07495	COG0477	Major facilitator Superfamily
AZK53_07500	COG0156	8-amino-7-oxononanoate synthase activity
AZK53_07505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AZK53_07515	COG2814	Major facilitator Superfamily
AZK53_07530	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_07535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_07545	COG1280	lysine exporter protein (LysE YggA)
AZK53_07550	COG1113	amino acid transport
AZK53_07555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZK53_07575	COG1113	amino acid transport
AZK53_07595	COG1609	Transcriptional regulator
AZK53_07600	COG2223	nitrite transmembrane transporter activity
AZK53_07610	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AZK53_07615	COG1621	beta-fructofuranosidase activity
AZK53_07620	COG3933	PFAM sigma-54 factor interaction domain-containing protein
AZK53_07620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AZK53_07625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_07630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_07635	COG3715	PTS system
AZK53_07640	COG3716	PTS system mannose fructose sorbose family IID component
AZK53_07645	COG1621	beta-fructofuranosidase activity
AZK53_07650	COG0765	amino acid transport
AZK53_07655	COG0765	amino acid transport
AZK53_07660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_07665	COG1464	Belongs to the NlpA lipoprotein family
AZK53_07670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_07675	COG2011	ABC-type metal ion transport system permease component
AZK53_07695	COG1464	Belongs to the NlpA lipoprotein family
AZK53_07700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_07705	COG2011	ABC-type metal ion transport system permease component
AZK53_07710	COG1464	Belongs to the NlpA lipoprotein family
AZK53_07720	COG0024	Methionine aminopeptidase
AZK53_07730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZK53_07740	COG0656	L-ascorbic acid biosynthetic process
AZK53_07745	COG2986	histidine ammonia-lyase
AZK53_07755	COG1228	amidohydrolase
AZK53_07760	COG0010	Belongs to the arginase family
AZK53_07765	COG1846	Transcriptional regulator
AZK53_07770	COG1957	nucleoside hydrolase
AZK53_07780	COG1288	antiporter activity
AZK53_07785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AZK53_07815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_07835	COG2364	Membrane
AZK53_07840	COG1846	Transcriptional regulator
AZK53_07845	COG0456	acetyltransferase
AZK53_07875	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_07875	COG3848	Pyruvate phosphate dikinase
AZK53_07880	COG1309	transcriptional regulator
AZK53_07885	COG2814	Major facilitator Superfamily
AZK53_07890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AZK53_07895	COG3958	Transketolase
AZK53_07900	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_07905	COG2186	Transcriptional regulator
AZK53_07920	COG0698	ribose 5-phosphate isomerase
AZK53_07945	COG0791	NLP P60 protein
AZK53_07945	COG1388	LysM domain
AZK53_07950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AZK53_07965	COG2318	DinB family
AZK53_07990	COG0583	DNA-binding transcription factor activity
AZK53_07995	COG0596	Alpha beta hydrolase
AZK53_08020	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_08035	COG3850	Histidine kinase
AZK53_08035	COG5002	protein histidine kinase activity
AZK53_08040	COG0745	RESPONSE REGULATOR receiver
AZK53_08045	COG0586	Pfam SNARE associated Golgi protein
AZK53_08055	COG0726	polysaccharide deacetylase
AZK53_08065	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AZK53_08075	COG0697	spore germination
AZK53_08080	COG4977	sequence-specific DNA binding
AZK53_08105	COG0387	Pfam Sodium calcium exchanger
AZK53_08110	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_08125	COG1309	transcriptional regulator
AZK53_08130	COG0861	Integral membrane protein TerC family
AZK53_08140	COG5577	PFAM Coat F domain
AZK53_08155	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_08165	COG1522	sequence-specific DNA binding
AZK53_08185	COG2076	Multidrug Resistance protein
AZK53_08200	COG1278	Cold shock
AZK53_08210	COG0513	Belongs to the DEAD box helicase family
AZK53_08215	COG1278	Cold shock
AZK53_08230	COG0028	Belongs to the TPP enzyme family
AZK53_08265	COG2172	sigma factor antagonist activity
AZK53_08270	COG3858	chitin binding
AZK53_08270	COG1388	LysM domain
AZK53_08275	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_08300	COG2226	methyltransferase
AZK53_08310	COG1733	regulation of RNA biosynthetic process
AZK53_08315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_08330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_08335	COG3420	alginic acid biosynthetic process
AZK53_08355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZK53_08360	COG0640	Transcriptional regulator
AZK53_08370	COG0640	Transcriptional regulator
AZK53_08375	COG0346	lactoylglutathione lyase activity
AZK53_08380	COG0475	glutathione-regulated potassium exporter activity
AZK53_08380	COG0589	response to stress
AZK53_08390	COG2076	Multidrug Resistance protein
AZK53_08395	COG2076	Multidrug Resistance protein
AZK53_08445	COG0583	DNA-binding transcription factor activity
AZK53_08450	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AZK53_08460	COG0753	catalase activity
AZK53_08475	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_08480	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_08500	COG0384	phenazine biosynthesis protein PhzF
AZK53_08510	COG5577	PFAM Coat F domain
AZK53_08520	COG1063	alcohol dehydrogenase
AZK53_08525	COG5577	PFAM Coat F domain
AZK53_08535	COG2814	Major facilitator Superfamily
AZK53_08545	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_08560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_08570	COG0789	Transcriptional regulator
AZK53_08575	COG1278	Cold shock
AZK53_08615	COG1113	amino acid transport
AZK53_08625	COG2207	Transcriptional regulator
AZK53_08655	COG0745	RESPONSE REGULATOR receiver
AZK53_08660	COG0745	RESPONSE REGULATOR receiver
AZK53_08665	COG5002	protein histidine kinase activity
AZK53_08670	COG0671	phosphoesterase, PA-phosphatase related
AZK53_08680	COG2851	Citrate transporter
AZK53_08730	COG2318	DinB family
AZK53_08735	COG2890	protein-(glutamine-N5) methyltransferase activity
AZK53_08775	COG2311	Membrane
AZK53_08810	COG1114	Component of the transport system for branched-chain amino acids
AZK53_08820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AZK53_08830	COG4282	regulation of fungal-type cell wall biogenesis
AZK53_08855	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_08855	COG3848	Pyruvate phosphate dikinase
AZK53_08860	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AZK53_08870	COG0601	transmembrane transport
AZK53_08880	COG0444	Belongs to the ABC transporter superfamily
AZK53_08885	COG4608	Belongs to the ABC transporter superfamily
AZK53_08890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AZK53_08895	COG0477	Major facilitator Superfamily
AZK53_08910	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_08945	COG0517	IMP dehydrogenase activity
AZK53_08965	COG1309	transcriptional regulator
AZK53_08975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZK53_08980	COG1845	cytochrome c oxidase, subunit III
AZK53_08990	COG0589	response to stress
AZK53_08995	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_09000	COG1612	heme a metabolic process
AZK53_09005	COG2072	flavoprotein involved in K transport
AZK53_09015	COG2252	PERMEase
AZK53_09020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZK53_09025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZK53_09030	COG0022	dehydrogenase e1 component
AZK53_09035	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_09040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZK53_09045	COG3284	Transcriptional regulator
AZK53_09050	COG1063	alcohol dehydrogenase
AZK53_09060	COG1846	Transcriptional regulator
AZK53_09080	COG0628	permease
AZK53_09085	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_09095	COG2211	Major facilitator Superfamily
AZK53_09120	COG0589	response to stress
AZK53_09125	COG5002	protein histidine kinase activity
AZK53_09135	COG1937	Protein conserved in bacteria
AZK53_09140	COG2608	mercury ion transmembrane transporter activity
AZK53_09145	COG2217	Heavy metal translocating P-type atpase
AZK53_09155	COG1388	LysM domain
AZK53_09160	COG2271	Major facilitator Superfamily
AZK53_09190	COG0640	Transcriptional regulator
AZK53_09195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AZK53_09200	COG0551	DNA topoisomerase type I activity
AZK53_09200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZK53_09205	COG5444	nuclease activity
AZK53_09220	COG2050	protein possibly involved in aromatic compounds catabolism
AZK53_09225	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AZK53_09230	COG2323	membrane
AZK53_09245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_09250	COG1802	Transcriptional regulator
AZK53_09255	COG0473	3-isopropylmalate dehydrogenase activity
AZK53_09260	COG2814	Major facilitator Superfamily
AZK53_09265	COG1733	regulation of RNA biosynthetic process
AZK53_09270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZK53_09270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AZK53_09275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZK53_09275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AZK53_09295	COG5566	PFAM Mor transcription activator
AZK53_09310	COG0561	phosphatase activity
AZK53_09315	COG1876	peptidase activity
AZK53_09320	COG0726	polysaccharide deacetylase
AZK53_09355	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AZK53_09370	COG0386	Belongs to the glutathione peroxidase family
AZK53_09375	COG1418	mRNA catabolic process
AZK53_09380	COG0488	(ABC) transporter
AZK53_09385	COG1413	lyase activity
AZK53_09390	COG0726	polysaccharide deacetylase
AZK53_09400	COG2136	Putative SAM-dependent methyltransferase
AZK53_09400	COG2521	methyltransferase
AZK53_09410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_09415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_09425	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AZK53_09430	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZK53_09435	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
AZK53_09440	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AZK53_09445	COG0406	alpha-ribazole phosphatase activity
AZK53_09455	COG2096	Adenosyltransferase
AZK53_09460	COG2962	Rard protein
AZK53_09470	COG0523	cobalamin synthesis protein
AZK53_09475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZK53_09480	COG0322	excinuclease ABC activity
AZK53_09490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZK53_09495	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZK53_09500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AZK53_09510	COG3011	Protein conserved in bacteria
AZK53_09515	COG1595	DNA-templated transcription, initiation
AZK53_09535	COG2002	toxin-antitoxin pair type II binding
AZK53_09540	COG0534	Mate efflux family protein
AZK53_09545	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_09570	COG1368	sulfuric ester hydrolase activity
AZK53_09580	COG3853	Toxic anion resistance protein (TelA)
AZK53_09595	COG0726	polysaccharide deacetylase
AZK53_09605	COG2234	aminopeptidase activity
AZK53_09610	COG5002	protein histidine kinase activity
AZK53_09620	COG1823	symporter activity
AZK53_09625	COG1523	belongs to the glycosyl hydrolase 13 family
AZK53_09630	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_09635	COG2124	cytochrome p450
AZK53_09635	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AZK53_09640	COG2112	serine threonine protein kinase
AZK53_09650	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AZK53_09655	COG1360	Flagellar Motor Protein
AZK53_09670	COG3361	conserved protein (COG2071)
AZK53_09675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AZK53_09680	COG1757	Na H antiporter
AZK53_09690	COG0833	amino acid
AZK53_09695	COG3594	Acyltransferase
AZK53_09700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AZK53_09705	COG0745	RESPONSE REGULATOR receiver
AZK53_09710	COG5002	protein histidine kinase activity
AZK53_09715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZK53_09720	COG3104	oligopeptide transport
AZK53_09730	COG0281	malic enzyme
AZK53_09735	COG3493	citrate carrier protein
AZK53_09740	COG0561	phosphatase activity
AZK53_09745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_09760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AZK53_09765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_09770	COG0765	amino acid transport
AZK53_09775	COG0765	amino acid transport
AZK53_09780	COG1126	abc transporter atp-binding protein
AZK53_09785	COG0196	riboflavin kinase activity
AZK53_09790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_09800	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_09840	COG1611	Belongs to the LOG family
AZK53_09845	COG0281	malic enzyme
AZK53_09850	COG3402	PFAM membrane-flanked domain
AZK53_09855	COG3428	Bacterial PH domain
AZK53_09870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_09875	COG0109	protoheme IX farnesyltransferase activity
AZK53_09880	COG4195	phage-related replication protein
AZK53_09890	COG0789	Transcriptional regulator
AZK53_09920	COG0583	DNA-binding transcription factor activity
AZK53_09925	COG0067	glutamate synthase
AZK53_09925	COG0070	glutamate synthase
AZK53_09925	COG0069	glutamate synthase activity
AZK53_09930	COG0493	'glutamate synthase
AZK53_09950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AZK53_09965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_09975	COG1846	Transcriptional regulator
AZK53_09980	COG1380	Effector of murein hydrolase LrgA
AZK53_09985	COG1346	cytolysis
AZK53_09990	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_10005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AZK53_10010	COG0463	Glycosyl transferase, family 2
AZK53_10020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_10025	COG0745	RESPONSE REGULATOR receiver
AZK53_10040	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AZK53_10050	COG4208	sulfate ABC transporter
AZK53_10065	COG0745	RESPONSE REGULATOR receiver
AZK53_10090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_10100	COG1349	DNA-binding transcription factor activity
AZK53_10105	COG1105	Belongs to the carbohydrate kinase PfkB family
AZK53_10110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_10110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZK53_10110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AZK53_10115	COG0527	aspartate kinase activity
AZK53_10125	COG2032	superoxide dismutase activity
AZK53_10140	COG0300	oxidoreductase activity
AZK53_10145	COG0640	Transcriptional regulator
AZK53_10150	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_10155	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AZK53_10170	COG0733	neurotransmitter:sodium symporter activity
AZK53_10175	COG3773	Cell wall hydrolase
AZK53_10195	COG0673	inositol 2-dehydrogenase activity
AZK53_10200	COG1082	Xylose isomerase domain protein TIM barrel
AZK53_10205	COG2094	Belongs to the DNA glycosylase MPG family
AZK53_10210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZK53_10220	COG0454	-acetyltransferase
AZK53_10230	COG2814	Major facilitator Superfamily
AZK53_10245	COG3871	stress protein (general stress protein 26)
AZK53_10270	COG1595	DNA-templated transcription, initiation
AZK53_10275	COG4873	Protein conserved in bacteria
AZK53_10280	COG0714	Associated with various cellular activities
AZK53_10285	COG4548	von Willebrand factor, type A
AZK53_10290	COG0697	spore germination
AZK53_10300	COG2207	Transcriptional regulator
AZK53_10305	COG1994	Peptidase M50
AZK53_10310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_10315	COG1119	ATPase activity
AZK53_10330	COG1657	PFAM Prenyltransferase squalene oxidase
AZK53_10340	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AZK53_10340	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AZK53_10350	COG0384	phenazine biosynthesis protein PhzF
AZK53_10365	COG1378	Sugar-specific transcriptional regulator TrmB
AZK53_10370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_10375	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_10395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_10400	COG1279	arginine transmembrane transporter activity
AZK53_10425	COG1396	sequence-specific DNA binding
AZK53_10440	COG0494	nUDIX hydrolase
AZK53_10445	COG1335	isochorismatase
AZK53_10450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AZK53_10455	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZK53_10460	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AZK53_10465	COG1098	S1 RNA binding domain
AZK53_10470	COG1404	Belongs to the peptidase S8 family
AZK53_10475	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_10480	COG1254	Belongs to the acylphosphatase family
AZK53_10485	COG2223	nitrite transmembrane transporter activity
AZK53_10490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_10500	COG2207	Transcriptional regulator
AZK53_10500	COG0662	Cupin 2, conserved barrel domain protein
AZK53_10505	COG0697	spore germination
AZK53_10510	COG0488	(ABC) transporter
AZK53_10515	COG0697	spore germination
AZK53_10520	COG0531	amino acid
AZK53_10535	COG1131	(ABC) transporter
AZK53_10540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZK53_10545	COG1757	Na H antiporter
AZK53_10550	COG1609	Transcriptional regulator
AZK53_10560	COG1533	DNA photolyase activity
AZK53_10580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZK53_10580	COG0551	DNA topoisomerase type I activity
AZK53_10590	COG0446	pyridine nucleotide-disulphide oxidoreductase
AZK53_10620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_10640	COG1757	Na H antiporter
AZK53_10665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_10670	COG2720	vancomycin resistance protein
AZK53_10710	COG0514	ATP-dependent DNA helicase (RecQ)
AZK53_10740	COG1575	Belongs to the MenA family. Type 1 subfamily
AZK53_10745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AZK53_10760	COG2814	Major facilitator Superfamily
AZK53_10765	COG0583	DNA-binding transcription factor activity
AZK53_10770	COG1725	Transcriptional regulator
AZK53_10775	COG1131	(ABC) transporter
AZK53_10785	COG1595	DNA-templated transcription, initiation
AZK53_10800	COG1764	response to oxidative stress
AZK53_10805	COG1846	Transcriptional regulator
AZK53_10820	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
AZK53_10830	COG1388	LysM domain
AZK53_10830	COG3584	3D domain protein
AZK53_10850	COG5002	protein histidine kinase activity
AZK53_10855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZK53_10860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AZK53_10865	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AZK53_10880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZK53_10895	COG2409	Drug exporters of the RND superfamily
AZK53_10900	COG1834	amidinotransferase
AZK53_10910	COG1295	ribonuclease BN
AZK53_10990	COG0110	maltose O-acetyltransferase activity
AZK53_10995	COG0346	lactoylglutathione lyase activity
AZK53_11005	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_11015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AZK53_11020	COG2176	DNA-directed DNA polymerase activity
AZK53_11035	COG0114	fumarate hydratase activity
AZK53_11045	COG3757	hydrolase, family 25
AZK53_11045	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_11055	COG5002	protein histidine kinase activity
AZK53_11090	COG0778	Nitroreductase
AZK53_11100	COG0300	oxidoreductase activity
AZK53_11105	COG3290	protein histidine kinase activity
AZK53_11110	COG4565	transcriptional regulatory protein
AZK53_11115	COG2851	Citrate transporter
AZK53_11125	COG2610	gluconate transmembrane transporter activity
AZK53_11130	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_11135	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZK53_11165	COG0583	DNA-binding transcription factor activity
AZK53_11175	COG1301	dicarboxylic acid transport
AZK53_11180	COG0019	diaminopimelate decarboxylase activity
AZK53_11190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_11200	COG4191	Histidine kinase
AZK53_11210	COG1960	acyl-CoA dehydrogenase activity
AZK53_11215	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_11220	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_11230	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZK53_11235	COG1024	Enoyl-CoA hydratase
AZK53_11250	COG2045	Belongs to the ComB family
AZK53_11255	COG1960	acyl-CoA dehydrogenase activity
AZK53_11260	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_11265	COG1024	Enoyl-CoA hydratase
AZK53_11280	COG1141	Ferredoxin
AZK53_11290	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZK53_11300	COG0183	Belongs to the thiolase family
AZK53_11305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_11330	COG1509	lysine 2,3-aminomutase activity
AZK53_11340	COG0833	amino acid
AZK53_11345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_11360	COG1979	alcohol dehydrogenase
AZK53_11365	COG0738	Major facilitator superfamily
AZK53_11370	COG1181	Belongs to the D-alanine--D-alanine ligase family
AZK53_11390	COG3977	Valine--pyruvate aminotransferase
AZK53_11395	COG3773	Cell wall hydrolase
AZK53_11405	COG3119	arylsulfatase activity
AZK53_11420	COG0531	amino acid
AZK53_11430	COG1846	Transcriptional regulator
AZK53_11435	COG1033	growth of symbiont in host cell
AZK53_11435	COG2409	Drug exporters of the RND superfamily
AZK53_11440	COG2202	Pas domain
AZK53_11440	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_11445	COG3832	glyoxalase III activity
AZK53_11450	COG0640	Transcriptional regulator
AZK53_11460	COG2267	carboxylic ester hydrolase activity
AZK53_11470	COG3386	PFAM SMP-30 Gluconolaconase
AZK53_11480	COG2368	4-hydroxyphenylacetate
AZK53_11485	COG3739	integral membrane protein
AZK53_11495	COG0326	Molecular chaperone. Has ATPase activity
AZK53_11500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZK53_11520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZK53_11525	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_11525	COG3757	hydrolase, family 25
AZK53_11535	COG0697	spore germination
AZK53_11540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_11555	COG4572	Cation transport regulator
AZK53_11560	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AZK53_11565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AZK53_11665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_11680	COG0494	nUDIX hydrolase
AZK53_11685	COG0702	epimerase
AZK53_11690	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_11695	COG1846	Transcriptional regulator
AZK53_11700	COG2720	vancomycin resistance protein
AZK53_11705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZK53_11730	COG0076	glutamate decarboxylase activity
AZK53_11755	COG2116	formate transmembrane transporter activity
AZK53_11760	COG5609	conserved protein (DUF2294)
AZK53_11775	COG2271	Major facilitator Superfamily
AZK53_11780	COG0277	FAD linked oxidase domain protein
AZK53_11785	COG0840	transmembrane signaling receptor activity
AZK53_11795	COG0622	Phosphoesterase
AZK53_11805	COG1408	metallophosphoesterase
AZK53_11810	COG3663	DNA glycosylase
AZK53_11815	COG3883	PFAM NLP P60 protein
AZK53_11815	COG0791	NLP P60 protein
AZK53_11820	COG1587	Uroporphyrinogen-III synthase
AZK53_11825	COG1414	Transcriptional regulator
AZK53_11830	COG0439	Biotin carboxylase
AZK53_11835	COG0511	ligase activity, forming carbon-carbon bonds
AZK53_11840	COG1984	allophanate hydrolase subunit 2
AZK53_11845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_11850	COG4336	lyase activity
AZK53_11855	COG1914	H( )-stimulated, divalent metal cation uptake system
AZK53_11860	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AZK53_11875	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_11880	COG1268	BioY protein
AZK53_11885	COG0183	Belongs to the thiolase family
AZK53_11905	COG0431	NADPH-dependent FMN reductase
AZK53_11910	COG2197	response regulator
AZK53_11915	COG4585	Histidine kinase
AZK53_11915	COG2203	Gaf domain
AZK53_11935	COG0697	spore germination
AZK53_11945	COG2153	protein acetylation
AZK53_11950	COG0129	dihydroxy-acid dehydratase activity
AZK53_11955	COG2267	carboxylic ester hydrolase activity
AZK53_11960	COG1227	inorganic diphosphatase activity
AZK53_11980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AZK53_11990	COG0204	Acyl-transferase
AZK53_11995	COG2233	PERMEase
AZK53_12000	COG3195	allantoin biosynthetic process
AZK53_12000	COG3648	Uricase
AZK53_12025	COG1914	H( )-stimulated, divalent metal cation uptake system
AZK53_12045	COG1846	Transcriptional regulator
AZK53_12055	COG4974	Belongs to the 'phage' integrase family
AZK53_12070	COG0531	amino acid
AZK53_12075	COG4302	ethanolamine ammonia-lyase activity
AZK53_12080	COG4303	Ethanolamine ammonia lyase large subunit
AZK53_12085	COG4819	ethanolamine utilization protein
AZK53_12095	COG0833	amino acid
AZK53_12105	COG1247	-acetyltransferase
AZK53_12110	COG1335	isochorismatase
AZK53_12120	COG3403	YqcI/YcgG family
AZK53_12125	COG1280	lysine exporter protein (LysE YggA)
AZK53_12130	COG2267	carboxylic ester hydrolase activity
AZK53_12135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZK53_12140	COG0187	DNA topoisomerase II activity
AZK53_12145	COG1832	CoA-binding protein
AZK53_12150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZK53_12155	COG4841	protein insertion into membrane
AZK53_12160	COG0824	Thioesterase
AZK53_12185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_12190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AZK53_12210	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AZK53_12245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AZK53_12250	COG2068	MobA-Related Protein
AZK53_12255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AZK53_12310	COG1183	phosphatidylcholine synthase activity
AZK53_12325	COG2814	Major facilitator Superfamily
AZK53_12330	COG1683	Conserved Protein
AZK53_12335	COG1302	Protein conserved in bacteria
AZK53_12350	COG1295	ribonuclease BN
AZK53_12360	COG1115	amino acid carrier protein
AZK53_12365	COG2814	Major facilitator Superfamily
AZK53_12375	COG2814	Major facilitator Superfamily
AZK53_12380	COG0789	Transcriptional regulator
AZK53_12390	COG0288	reversible hydration of carbon dioxide
AZK53_12395	COG0659	secondary active sulfate transmembrane transporter activity
AZK53_12400	COG0745	RESPONSE REGULATOR receiver
AZK53_12405	COG5002	protein histidine kinase activity
AZK53_12415	COG0477	Major facilitator Superfamily
AZK53_12420	COG4282	regulation of fungal-type cell wall biogenesis
AZK53_12425	COG0531	amino acid
AZK53_12435	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_12440	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AZK53_12510	COG1363	Peptidase, m42
AZK53_12520	COG1114	Component of the transport system for branched-chain amino acids
AZK53_12540	COG0004	ammonium transporteR
AZK53_12555	COG1252	NADH dehydrogenase
AZK53_12560	COG0679	Auxin Efflux Carrier
AZK53_12565	COG0281	malic enzyme
AZK53_12570	COG1473	amidohydrolase
AZK53_12575	COG2271	Major facilitator Superfamily
AZK53_12595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AZK53_12600	COG0163	prenyltransferase activity
AZK53_12605	COG0583	DNA-binding transcription factor activity
AZK53_12610	COG0679	Auxin Efflux Carrier
AZK53_12630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_12635	COG0247	lactate metabolic process
AZK53_12640	COG0277	FAD linked oxidase domain protein
AZK53_12645	COG3835	regulator
AZK53_12650	COG0693	protein deglycase activity
AZK53_12660	COG2610	gluconate transmembrane transporter activity
AZK53_12680	COG1131	(ABC) transporter
AZK53_12690	COG2197	response regulator
AZK53_12725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_12735	COG0586	Pfam SNARE associated Golgi protein
AZK53_12740	COG1515	deoxyribonuclease V activity
AZK53_12745	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_12750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_12750	COG3153	acetyltransferase
AZK53_12760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AZK53_12765	COG0531	amino acid
AZK53_12800	COG2849	repeat protein
AZK53_12805	COG5444	nuclease activity
AZK53_12820	COG0534	Mate efflux family protein
AZK53_12825	COG1566	PFAM secretion protein HlyD family protein
AZK53_12835	COG1846	Transcriptional regulator
AZK53_12840	COG0708	Exodeoxyribonuclease III
AZK53_12855	COG0673	inositol 2-dehydrogenase activity
AZK53_12860	COG1349	DNA-binding transcription factor activity
AZK53_12865	COG3853	Toxic anion resistance protein (TelA)
AZK53_12875	COG2310	stress, protein
AZK53_12880	COG2310	stress, protein
AZK53_12885	COG2310	stress, protein
AZK53_12890	COG0737	Belongs to the 5'-nucleotidase family
AZK53_12905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZK53_12910	COG1131	(ABC) transporter
AZK53_12920	COG2084	Dehydrogenase
AZK53_12925	COG1278	Cold shock
AZK53_12930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_12935	COG0028	Belongs to the TPP enzyme family
AZK53_12940	COG1278	Cold shock
AZK53_12970	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_12980	COG0427	acetyl-CoA hydrolase
AZK53_12985	COG3279	Response regulator of the LytR AlgR family
AZK53_12990	COG2323	membrane
AZK53_12995	COG2814	Major facilitator Superfamily
AZK53_13000	COG1388	LysM domain
AZK53_13000	COG3584	3D domain protein
AZK53_13005	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AZK53_13030	COG3340	Belongs to the peptidase S51 family
AZK53_13125	COG2318	DinB family
AZK53_13135	COG0579	oxidoreductase
AZK53_13170	COG1486	melibiose metabolic process
AZK53_13220	COG0596	Alpha beta hydrolase
AZK53_13225	COG1929	Belongs to the glycerate kinase type-1 family
AZK53_13230	COG2610	gluconate transmembrane transporter activity
AZK53_13235	COG3835	regulator
AZK53_13240	COG1454	alcohol dehydrogenase
AZK53_13245	COG3152	Membrane
AZK53_13270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_13275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_13300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZK53_13310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AZK53_13325	COG2390	Transcriptional regulator
AZK53_13355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AZK53_13360	COG0501	Belongs to the peptidase M48B family
AZK53_13365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_13370	COG1742	UPF0060 membrane protein
AZK53_13375	COG2182	Extracellular solute-binding protein
AZK53_13395	COG2031	fatty acid transporter
AZK53_13425	COG2391	methyltransferase activity
AZK53_13440	COG1979	alcohol dehydrogenase
AZK53_13445	COG0583	DNA-binding transcription factor activity
AZK53_13455	COG0456	acetyltransferase
AZK53_13485	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_13490	COG1063	alcohol dehydrogenase
AZK53_13515	COG0025	NhaP-type Na H and K H
AZK53_13520	COG1253	flavin adenine dinucleotide binding
AZK53_13530	COG4325	translation initiation factor activity
AZK53_13545	COG4608	Belongs to the ABC transporter superfamily
AZK53_13555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_13560	COG0601	transmembrane transport
AZK53_13565	COG0747	negative chemotaxis
AZK53_13575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_13590	COG1525	nuclease
AZK53_13600	COG0579	oxidoreductase
AZK53_13605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZK53_13610	COG0561	phosphatase activity
AZK53_13625	COG0668	transmembrane transport
AZK53_13650	COG2309	aminopeptidase activity
AZK53_13655	COG1414	Transcriptional regulator
AZK53_13665	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AZK53_13670	COG0277	FAD linked oxidase domain protein
AZK53_13675	COG0247	lactate metabolic process
AZK53_13680	COG0277	FAD linked oxidase domain protein
AZK53_13685	COG1620	l-lactate permease
AZK53_13705	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AZK53_13730	COG1595	DNA-templated transcription, initiation
AZK53_13750	COG4682	membrane
AZK53_13765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_13770	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_13775	COG0598	Magnesium transport protein CorA
AZK53_13780	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZK53_13790	COG2323	membrane
AZK53_13795	COG1876	peptidase activity
AZK53_13810	COG5002	protein histidine kinase activity
AZK53_13815	COG0745	RESPONSE REGULATOR receiver
AZK53_13835	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_13840	COG0567	Dehydrogenase, E1 component
AZK53_13850	COG2814	Major facilitator Superfamily
AZK53_13855	COG1764	response to oxidative stress
AZK53_13865	COG2311	Membrane
AZK53_13915	COG0559	Belongs to the binding-protein-dependent transport system permease family
AZK53_13925	COG0347	Belongs to the P(II) protein family
AZK53_13930	COG0004	ammonium transporteR
AZK53_13935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AZK53_13950	COG0596	Alpha beta hydrolase
AZK53_13960	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AZK53_13960	COG0456	acetyltransferase
AZK53_13965	COG1960	acyl-CoA dehydrogenase activity
AZK53_14005	COG4604	ABC transporter, ATP-binding protein
AZK53_14010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_14015	COG1492	cobalamin metabolic process
AZK53_14025	COG0531	amino acid
AZK53_14035	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_14040	COG2404	hydrolase activity, acting on ester bonds
AZK53_14045	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AZK53_14055	COG1609	Transcriptional regulator
AZK53_14065	COG2271	Major facilitator Superfamily
AZK53_14070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AZK53_14085	COG1233	COG1233 Phytoene dehydrogenase and related
AZK53_14090	COG0463	Glycosyl transferase, family 2
AZK53_14135	COG0804	urea catabolic process
AZK53_14145	COG0831	urea catabolic process
AZK53_14150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZK53_14155	COG1388	LysM domain
AZK53_14155	COG0791	NLP P60 protein
AZK53_14160	COG1388	LysM domain
AZK53_14160	COG3584	3D domain protein
AZK53_14165	COG0778	Nitroreductase
AZK53_14170	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZK53_14175	COG0586	Pfam SNARE associated Golgi protein
AZK53_14185	COG0400	carboxylic ester hydrolase activity
AZK53_14190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_14195	COG2244	polysaccharide biosynthetic process
AZK53_14200	COG0697	spore germination
AZK53_14205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_14225	COG1132	(ABC) transporter
AZK53_14250	COG4195	phage-related replication protein
AZK53_14260	COG0783	Belongs to the Dps family
AZK53_14270	COG5577	PFAM Coat F domain
AZK53_14275	COG1253	flavin adenine dinucleotide binding
AZK53_14290	COG0516	GMP reductase activity
AZK53_14290	COG0517	IMP dehydrogenase activity
AZK53_14300	COG0723	plastoquinol--plastocyanin reductase activity
AZK53_14300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_14315	COG0287	Prephenate dehydrogenase
AZK53_14325	COG1605	Chorismate mutase
AZK53_14325	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AZK53_14335	COG2059	Chromate
AZK53_14340	COG2059	Chromate
AZK53_14350	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AZK53_14355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_14360	COG2508	Transcriptional regulator
AZK53_14365	COG0011	TIGRFAM Protein of
AZK53_14370	COG0791	NLP P60 protein
AZK53_14370	COG1388	LysM domain
AZK53_14375	COG0753	catalase activity
AZK53_14385	COG0733	neurotransmitter:sodium symporter activity
AZK53_14425	COG0730	response to heat
AZK53_14430	COG1902	pentaerythritol trinitrate reductase activity
AZK53_14445	COG2205	protein histidine kinase activity
AZK53_14475	COG0640	Transcriptional regulator
AZK53_14485	COG0778	Nitroreductase
AZK53_14500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AZK53_14505	COG4991	sh3 domain protein
AZK53_14505	COG3103	Sh3 type 3 domain protein
AZK53_14505	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_14510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AZK53_14515	COG2002	toxin-antitoxin pair type II binding
AZK53_14520	COG2318	DinB family
AZK53_14525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AZK53_14535	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AZK53_14540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_14555	COG2211	Major facilitator Superfamily
AZK53_14560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_14565	COG1597	lipid kinase activity
AZK53_14575	COG0372	Belongs to the citrate synthase family
AZK53_14580	COG0583	DNA-binding transcription factor activity
AZK53_14585	COG0697	spore germination
AZK53_14590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_14605	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_14605	COG2202	Pas domain
AZK53_14610	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_14640	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_14645	COG2261	transglycosylase associated protein
AZK53_14655	COG0740	serine-type endopeptidase activity
AZK53_14670	COG1027	Aspartate ammonia-lyase
AZK53_14675	COG0252	asparaginase activity
AZK53_14680	COG1396	sequence-specific DNA binding
AZK53_14695	COG0640	Transcriptional regulator
AZK53_14715	COG0531	amino acid
AZK53_14720	COG1959	2 iron, 2 sulfur cluster binding
AZK53_14740	COG0281	malic enzyme
AZK53_14745	COG2746	aminoglycoside 3-N-acetyltransferase activity
AZK53_14755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_14760	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_14770	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AZK53_14775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AZK53_14785	COG0477	Major facilitator Superfamily
AZK53_14790	COG1846	Transcriptional regulator
AZK53_14795	COG0789	Transcriptional regulator
AZK53_14800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_14835	COG1819	glycosyl
AZK53_14850	COG1902	pentaerythritol trinitrate reductase activity
AZK53_14860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZK53_14875	COG2814	Major facilitator Superfamily
AZK53_14885	COG1228	amidohydrolase
AZK53_14895	COG1316	TRANSCRIPTIONal
AZK53_14900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_14920	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AZK53_14930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AZK53_14935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AZK53_14995	COG1280	lysine exporter protein (LysE YggA)
AZK53_15000	COG0531	amino acid
AZK53_15015	COG3764	Sortase (surface protein transpeptidase)
AZK53_15020	COG0730	response to heat
AZK53_15025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_15030	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AZK53_15040	COG2130	NADP-dependent
AZK53_15065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_15080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AZK53_15090	COG0501	Belongs to the peptidase M48B family
AZK53_15140	COG2076	Multidrug Resistance protein
AZK53_15145	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AZK53_15150	COG1278	Cold shock
AZK53_15155	COG2323	membrane
AZK53_15165	COG2910	NAD(P)H-binding
AZK53_15190	COG4607	ABC-type enterochelin transport system periplasmic component
AZK53_15195	COG4604	ABC transporter, ATP-binding protein
AZK53_15200	COG4605	iron ion homeostasis
AZK53_15205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_15210	COG3773	Cell wall hydrolase
AZK53_15230	COG1063	alcohol dehydrogenase
AZK53_15235	COG3775	system Galactitol-specific IIC component
AZK53_15240	COG3414	Phosphotransferase system galactitol-specific IIB component
AZK53_15245	COG3414	Phosphotransferase system galactitol-specific IIB component
AZK53_15260	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_15265	COG0681	Belongs to the peptidase S26 family
AZK53_15295	COG1349	DNA-binding transcription factor activity
AZK53_15310	COG1193	negative regulation of DNA recombination
AZK53_15320	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AZK53_15325	COG1396	sequence-specific DNA binding
AZK53_15330	COG0861	Integral membrane protein TerC family
AZK53_15335	COG1609	Transcriptional regulator
AZK53_15340	COG1959	2 iron, 2 sulfur cluster binding
AZK53_15400	COG3773	Cell wall hydrolase
AZK53_15405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZK53_15430	COG3546	catalase activity
AZK53_15450	COG1280	lysine exporter protein (LysE YggA)
AZK53_15455	COG1917	Cupin 2, conserved barrel domain protein
AZK53_15455	COG2207	Transcriptional regulator
AZK53_15460	COG4585	Histidine kinase
AZK53_15480	COG3209	COG3209 Rhs family protein
AZK53_15500	COG1819	glycosyl
AZK53_15505	COG0456	acetyltransferase
AZK53_15520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AZK53_15530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_15550	COG0346	lactoylglutathione lyase activity
AZK53_15555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AZK53_15570	COG1136	(ABC) transporter
AZK53_15575	COG0577	efflux transmembrane transporter activity
AZK53_15580	COG3850	Histidine kinase
AZK53_15580	COG5002	protein histidine kinase activity
AZK53_15605	COG5002	protein histidine kinase activity
AZK53_15610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_15615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AZK53_15640	COG4989	oxidoreductase activity
AZK53_15650	COG0697	spore germination
AZK53_15655	COG2207	Transcriptional regulator
AZK53_15655	COG1917	Cupin 2, conserved barrel domain protein
AZK53_15730	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AZK53_15740	COG0583	DNA-binding transcription factor activity
AZK53_15750	COG1301	dicarboxylic acid transport
AZK53_15755	COG2824	Alkylphosphonate utilization operon protein PhnA
AZK53_15785	COG0405	Gamma-glutamyltransferase
AZK53_15805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_15810	COG4521	taurine ABC transporter
AZK53_15815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AZK53_15820	COG2175	clavaminate synthase activity
AZK53_15825	COG2814	Major facilitator Superfamily
AZK53_15845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_15855	COG1960	acyl-CoA dehydrogenase activity
AZK53_15860	COG1063	alcohol dehydrogenase
AZK53_15865	COG0745	RESPONSE REGULATOR receiver
AZK53_15870	COG0642	Histidine kinase
AZK53_15875	COG1136	(ABC) transporter
AZK53_15880	COG0577	efflux transmembrane transporter activity
AZK53_15890	COG0412	Dienelactone hydrolase
AZK53_15895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_15900	COG0730	response to heat
AZK53_15905	COG0425	Belongs to the sulfur carrier protein TusA family
AZK53_15910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_15910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_15915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_15915	COG0425	Belongs to the sulfur carrier protein TusA family
AZK53_15930	COG2210	Belongs to the sulfur carrier protein TusA family
AZK53_15935	COG0425	Belongs to the sulfur carrier protein TusA family
AZK53_15940	COG1937	Protein conserved in bacteria
AZK53_15965	COG0583	DNA-binding transcription factor activity
AZK53_15985	COG2188	Transcriptional regulator
AZK53_15995	COG2723	6-phospho-beta-galactosidase activity
AZK53_16020	COG1280	lysine exporter protein (LysE YggA)
AZK53_16035	COG0583	DNA-binding transcription factor activity
AZK53_16040	COG2814	Major facilitator Superfamily
AZK53_16045	COG0346	lactoylglutathione lyase activity
AZK53_16065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZK53_16080	COG0778	Nitroreductase
AZK53_16085	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_16100	COG1704	LemA family
AZK53_16105	COG0726	polysaccharide deacetylase
AZK53_16120	COG1733	regulation of RNA biosynthetic process
AZK53_16125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_16130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_16135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AZK53_16150	COG2304	oxidoreductase activity
AZK53_16160	COG0346	lactoylglutathione lyase activity
AZK53_16165	COG2808	Putative FMN-binding domain
AZK53_16195	COG4807	Protein conserved in bacteria
AZK53_16205	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AZK53_16210	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_16215	COG1278	Cold shock
AZK53_16220	COG1278	Cold shock
AZK53_16235	COG0747	negative chemotaxis
AZK53_16240	COG0601	transmembrane transport
AZK53_16245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AZK53_16250	COG0444	Belongs to the ABC transporter superfamily
AZK53_16255	COG4608	Belongs to the ABC transporter superfamily
AZK53_16265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AZK53_16270	COG1301	dicarboxylic acid transport
AZK53_16280	COG0477	Major facilitator Superfamily
AZK53_16320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_16325	COG0659	secondary active sulfate transmembrane transporter activity
AZK53_16335	COG2211	Major facilitator Superfamily
AZK53_16345	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AZK53_16350	COG1691	(AIR) carboxylase
AZK53_16355	COG1606	tRNA processing
AZK53_16360	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_16370	COG1904	glucuronate isomerase
AZK53_16405	COG2329	Antibiotic biosynthesis monooxygenase
AZK53_16445	COG3655	Transcriptional regulator
AZK53_16455	COG0583	DNA-binding transcription factor activity
AZK53_16460	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_16475	COG1609	Transcriptional regulator
AZK53_16480	COG1082	Xylose isomerase domain protein TIM barrel
AZK53_16485	COG0673	inositol 2-dehydrogenase activity
AZK53_16505	COG3718	enzyme involved in inositol metabolism
AZK53_16510	COG3962	Belongs to the TPP enzyme family
AZK53_16515	COG1349	DNA-binding transcription factor activity
AZK53_16520	COG0191	fructose-bisphosphate aldolase activity
AZK53_16525	COG1082	Xylose isomerase domain protein TIM barrel
AZK53_16530	COG2814	Major facilitator Superfamily
AZK53_16545	COG1064	alcohol dehydrogenase
AZK53_16550	COG0789	Transcriptional regulator
AZK53_16565	COG0662	Cupin 2, conserved barrel domain protein
AZK53_16585	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_16590	COG1278	Cold shock
AZK53_16595	COG1876	peptidase activity
AZK53_16615	COG0598	Magnesium transport protein CorA
AZK53_16620	COG1366	Belongs to the anti-sigma-factor antagonist family
AZK53_16630	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_16640	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_16650	COG4335	DNA alkylation repair
AZK53_16655	COG0454	-acetyltransferase
AZK53_16670	COG2814	Major facilitator Superfamily
AZK53_16675	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_16675	COG3848	Pyruvate phosphate dikinase
AZK53_16680	COG0574	Belongs to the PEP-utilizing enzyme family
AZK53_16680	COG3848	Pyruvate phosphate dikinase
AZK53_16695	COG2186	Transcriptional regulator
AZK53_16715	COG3619	membrane
AZK53_16725	COG1349	DNA-binding transcription factor activity
AZK53_16730	COG0561	phosphatase activity
AZK53_16740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_16760	COG1280	lysine exporter protein (LysE YggA)
AZK53_16785	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AZK53_16800	COG2814	Major facilitator Superfamily
AZK53_16805	COG2160	L-arabinose isomerase activity
AZK53_16820	COG1609	Transcriptional regulator
AZK53_16825	COG1078	dGTPase activity
AZK53_16845	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZK53_16850	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZK53_16855	COG1918	ferrous iron import across plasma membrane
AZK53_16855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AZK53_16880	COG1846	Transcriptional regulator
AZK53_16910	COG0697	spore germination
AZK53_16915	COG0791	NLP P60 protein
AZK53_16915	COG1388	LysM domain
AZK53_16920	COG2258	MOSC domain
AZK53_16925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AZK53_16960	COG4974	Belongs to the 'phage' integrase family
AZK53_17005	COG3844	kynureninase activity
AZK53_17010	COG1113	amino acid transport
AZK53_17015	COG3483	tryptophan 2,3-dioxygenase activity
AZK53_17020	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AZK53_17025	COG1942	4-Oxalocrotonate Tautomerase
AZK53_17055	COG0251	oxidation-reduction process
AZK53_17070	COG0431	NADPH-dependent FMN reductase
AZK53_17075	COG0196	riboflavin kinase activity
AZK53_17080	COG2368	4-hydroxyphenylacetate
AZK53_17100	COG0789	Transcriptional regulator
AZK53_17135	COG5646	InterPro IPR014922
AZK53_17140	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
AZK53_17170	COG2258	MOSC domain
AZK53_17190	COG0583	DNA-binding transcription factor activity
AZK53_17195	COG2070	2-Nitropropane dioxygenase
AZK53_17200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZK53_17215	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_17245	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_17260	COG1501	Belongs to the glycosyl hydrolase 31 family
AZK53_17270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZK53_17280	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AZK53_17290	COG0300	oxidoreductase activity
AZK53_17300	COG0596	Alpha beta hydrolase
AZK53_17300	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_17305	COG1309	transcriptional regulator
AZK53_17310	COG1733	regulation of RNA biosynthetic process
AZK53_17315	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_17320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AZK53_17325	COG2226	methyltransferase
AZK53_17340	COG1942	4-Oxalocrotonate Tautomerase
AZK53_17345	COG0583	DNA-binding transcription factor activity
AZK53_17355	COG1522	sequence-specific DNA binding
AZK53_17365	COG2267	carboxylic ester hydrolase activity
AZK53_17375	COG1335	isochorismatase
AZK53_17385	COG0346	lactoylglutathione lyase activity
AZK53_17390	COG2259	Doxx family
AZK53_17415	COG1309	transcriptional regulator
AZK53_17420	COG2076	Multidrug Resistance protein
AZK53_17450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AZK53_17460	COG2851	Citrate transporter
AZK53_17470	COG0477	Major facilitator Superfamily
AZK53_17480	COG0477	Major facilitator Superfamily
AZK53_17485	COG1309	transcriptional regulator
AZK53_17495	COG2318	DinB family
AZK53_17505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AZK53_17520	COG1378	Sugar-specific transcriptional regulator TrmB
AZK53_17525	COG0697	spore germination
AZK53_17535	COG0583	DNA-binding transcription factor activity
AZK53_17575	COG1266	CAAX protease self-immunity
AZK53_17600	COG0252	asparaginase activity
AZK53_17620	COG1695	Transcriptional regulator
AZK53_17625	COG0656	L-ascorbic acid biosynthetic process
AZK53_17635	COG0583	DNA-binding transcription factor activity
AZK53_17645	COG2814	Major facilitator Superfamily
AZK53_17650	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_17670	COG1309	transcriptional regulator
AZK53_17720	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AZK53_17785	COG3339	Conserved Protein
AZK53_17800	COG3708	Transcriptional regulator
AZK53_17800	COG2207	Transcriptional regulator
AZK53_17815	COG1357	PFAM Pentapeptide repeats (8 copies)
AZK53_17825	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_17830	COG1733	regulation of RNA biosynthetic process
AZK53_17870	COG0303	'Molybdopterin
AZK53_17880	COG0521	Mo-molybdopterin cofactor biosynthetic process
AZK53_17885	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AZK53_17915	COG2244	polysaccharide biosynthetic process
AZK53_17935	COG2828	Protein conserved in bacteria
AZK53_17940	COG0583	DNA-binding transcription factor activity
AZK53_17945	COG2851	Citrate transporter
AZK53_17960	COG0670	Belongs to the BI1 family
AZK53_17980	COG0791	NLP P60 protein
AZK53_17985	COG2814	Major facilitator Superfamily
AZK53_17990	COG1846	Transcriptional regulator
AZK53_18005	COG1278	Cold shock
AZK53_18015	COG1113	amino acid transport
AZK53_18020	COG1113	amino acid transport
AZK53_18025	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_18030	COG0506	proline dehydrogenase activity
AZK53_18035	COG3878	Protein conserved in bacteria
AZK53_18050	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_18055	COG3300	MHYT domain
AZK53_18055	COG5001	Diguanylate cyclase
AZK53_18100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AZK53_18105	COG5609	conserved protein (DUF2294)
AZK53_18110	COG3223	Belongs to the PsiE family
AZK53_18140	COG0454	-acetyltransferase
AZK53_18150	COG0789	Transcriptional regulator
AZK53_18155	COG0667	Aldo Keto reductase
AZK53_18165	COG0789	Transcriptional regulator
AZK53_18190	COG1621	beta-fructofuranosidase activity
AZK53_18195	COG4980	gas vesicle protein
AZK53_18220	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZK53_18225	COG0577	efflux transmembrane transporter activity
AZK53_18230	COG1136	(ABC) transporter
AZK53_18240	COG0642	Histidine kinase
AZK53_18245	COG0745	RESPONSE REGULATOR receiver
AZK53_18255	COG1289	transmembrane transporter activity
AZK53_18260	COG1937	Protein conserved in bacteria
AZK53_18265	COG3209	COG3209 Rhs family protein
AZK53_18275	COG3973	AAA domain
AZK53_18280	COG1024	Enoyl-CoA hydratase
AZK53_18285	COG1733	regulation of RNA biosynthetic process
AZK53_18300	COG2124	cytochrome p450
AZK53_18305	COG2259	Doxx family
AZK53_18310	COG0463	Glycosyl transferase, family 2
AZK53_18320	COG0463	Glycosyl transferase, family 2
AZK53_18335	COG0791	NLP P60 protein
AZK53_18335	COG1388	LysM domain
AZK53_18340	COG0840	transmembrane signaling receptor activity
AZK53_18345	COG1846	Transcriptional regulator
AZK53_18355	COG1595	DNA-templated transcription, initiation
AZK53_18360	COG0726	polysaccharide deacetylase
AZK53_18365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AZK53_18380	COG0833	amino acid
AZK53_18390	COG0405	Gamma-glutamyltransferase
AZK53_18400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AZK53_18405	COG0569	domain protein
AZK53_18415	COG1522	sequence-specific DNA binding
AZK53_18425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZK53_18430	COG0745	RESPONSE REGULATOR receiver
AZK53_18435	COG2205	protein histidine kinase activity
AZK53_18435	COG2770	Histidine kinase
AZK53_18440	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AZK53_18445	COG1607	acyl-coa hydrolase
AZK53_18450	COG1802	Transcriptional regulator
AZK53_18455	COG0697	spore germination
AZK53_18465	COG0006	proline dipeptidase activity
AZK53_18475	COG1316	TRANSCRIPTIONal
AZK53_18485	COG2249	NAD(P)H dehydrogenase (quinone) activity
AZK53_18490	COG5522	Integral membrane protein (intg_mem_TP0381)
AZK53_18495	COG1174	glycine betaine transport
AZK53_18500	COG1125	glycine betaine transport
AZK53_18500	COG0517	IMP dehydrogenase activity
AZK53_18515	COG2814	Major facilitator Superfamily
AZK53_18525	COG0395	ABC-type sugar transport system, permease component
AZK53_18550	COG2205	protein histidine kinase activity
AZK53_18555	COG0730	response to heat
AZK53_18560	COG1301	dicarboxylic acid transport
AZK53_18595	COG1316	TRANSCRIPTIONal
AZK53_18600	COG1368	sulfuric ester hydrolase activity
AZK53_18610	COG0697	spore germination
AZK53_18615	COG1902	pentaerythritol trinitrate reductase activity
AZK53_18630	COG1113	amino acid transport
AZK53_18635	COG5505	Protein of unknown function (DUF819)
AZK53_18640	COG1309	transcriptional regulator
AZK53_18650	COG0583	DNA-binding transcription factor activity
AZK53_18655	COG0730	response to heat
AZK53_18660	COG1247	-acetyltransferase
AZK53_18665	COG2910	NAD(P)H-binding
AZK53_18670	COG1285	pathogenesis
AZK53_18675	COG2226	methyltransferase
AZK53_18680	COG4195	phage-related replication protein
AZK53_18685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AZK53_18700	COG1113	amino acid transport
AZK53_18725	COG0463	Glycosyl transferase, family 2
AZK53_18755	COG2514	catechol 2,3-dioxygenase activity
AZK53_18775	COG1280	lysine exporter protein (LysE YggA)
AZK53_18780	COG1115	amino acid carrier protein
AZK53_18790	COG0385	Bile acid
AZK53_18795	COG0668	transmembrane transport
AZK53_18800	COG2340	Cysteine-rich secretory protein family
AZK53_18805	COG1253	flavin adenine dinucleotide binding
AZK53_18815	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AZK53_18820	COG0589	response to stress
AZK53_18825	COG0205	6-phosphofructokinase activity
AZK53_18830	COG0791	NLP P60 protein
AZK53_18830	COG1388	LysM domain
AZK53_18840	COG0432	Pfam Uncharacterised protein family UPF0047
AZK53_18845	COG0697	spore germination
AZK53_18850	COG0814	amino acid
AZK53_18875	COG1131	(ABC) transporter
AZK53_18890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AZK53_18905	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_18915	COG1131	(ABC) transporter
AZK53_18940	COG1263	PTS System
AZK53_18940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_18945	COG3711	transcriptional antiterminator
AZK53_18950	COG2190	(PTS) system
AZK53_18955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AZK53_18970	COG0772	Belongs to the SEDS family
AZK53_18975	COG0659	secondary active sulfate transmembrane transporter activity
AZK53_18980	COG0813	purine-nucleoside phosphorylase activity
AZK53_18990	COG0671	phosphoesterase, PA-phosphatase related
AZK53_18995	COG4326	sporulation control protein
AZK53_19000	COG2815	serine threonine protein kinase
AZK53_19000	COG0515	serine threonine protein kinase
AZK53_19015	COG4479	Belongs to the UPF0346 family
AZK53_19020	COG3594	Acyltransferase
AZK53_19035	COG1509	lysine 2,3-aminomutase activity
AZK53_19040	COG0456	acetyltransferase
AZK53_19045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_19050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZK53_19055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZK53_19060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_19065	COG1301	dicarboxylic acid transport
AZK53_19075	COG4191	Histidine kinase
AZK53_19095	COG2755	lipolytic protein G-D-S-L family
AZK53_19100	COG1999	signal sequence binding
AZK53_19110	COG1307	EDD domain protein, DegV family
AZK53_19120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AZK53_19130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AZK53_19135	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AZK53_19140	COG0788	formyltetrahydrofolate deformylase activity
AZK53_19170	COG0076	glutamate decarboxylase activity
AZK53_19190	COG0415	Belongs to the DNA photolyase family
AZK53_19195	COG3852	Histidine kinase
AZK53_19210	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_19220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AZK53_19230	COG4846	Membrane protein involved in cytochrome C biogenesis
AZK53_19235	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
AZK53_19240	COG0785	Cytochrome C biogenesis protein
AZK53_19250	COG1132	(ABC) transporter
AZK53_19255	COG1132	(ABC) transporter
AZK53_19275	COG4224	UPF0291 protein
AZK53_19280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AZK53_19305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AZK53_19310	COG0531	amino acid
AZK53_19320	COG0174	glutamine synthetase
AZK53_19325	COG0789	Transcriptional regulator
AZK53_19330	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
AZK53_19335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AZK53_19340	COG2860	membrane
AZK53_19345	COG0464	growth
AZK53_19355	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AZK53_19365	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AZK53_19370	COG0531	amino acid
AZK53_19380	COG4550	Control of competence regulator ComK, YlbF/YmcA
AZK53_19385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZK53_19390	COG1013	pyruvate-flavodoxin oxidoreductase activity
AZK53_19395	COG0674	pyruvate-flavodoxin oxidoreductase activity
AZK53_19395	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AZK53_19405	COG2359	stage V sporulation protein S
AZK53_19410	COG1692	metallophosphoesterase
AZK53_19420	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AZK53_19425	COG1546	Belongs to the CinA family
AZK53_19425	COG1058	Belongs to the CinA family
AZK53_19430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AZK53_19435	COG1426	Protein conserved in bacteria
AZK53_19450	COG0300	oxidoreductase activity
AZK53_19455	COG0612	Peptidase, M16
AZK53_19460	COG0612	Peptidase, M16
AZK53_19485	COG2188	Transcriptional regulator
AZK53_19490	COG1674	ftsk spoiiie
AZK53_19490	COG4980	gas vesicle protein
AZK53_19500	COG0740	serine-type endopeptidase activity
AZK53_19505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AZK53_19515	COG0527	aspartate kinase activity
AZK53_19520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AZK53_19525	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZK53_19530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_19535	COG1873	PFAM PRC-barrel domain
AZK53_19540	COG0612	Peptidase, M16
AZK53_19545	COG0726	polysaccharide deacetylase
AZK53_19550	COG1185	polyribonucleotide nucleotidyltransferase activity
AZK53_19555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AZK53_19560	COG0196	riboflavin kinase activity
AZK53_19575	COG1550	Protein conserved in bacteria
AZK53_19585	COG1358	cellular component organization or biogenesis
AZK53_19590	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AZK53_19595	COG0195	Participates in both transcription termination and antitermination
AZK53_19600	COG0779	Required for maturation of 30S ribosomal subunits
AZK53_19605	COG2176	DNA-directed DNA polymerase activity
AZK53_19610	COG0442	prolyl-tRNA aminoacylation
AZK53_19615	COG0750	zinc metalloprotease
AZK53_19625	COG4589	Belongs to the CDS family
AZK53_19635	COG0233	cytoplasmic translational termination
AZK53_19640	COG0528	UMP kinase activity
AZK53_19645	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AZK53_19660	COG1191	sigma factor activity
AZK53_19665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AZK53_19670	COG0835	chemotaxis
AZK53_19675	COG2198	Histidine kinase
AZK53_19675	COG0643	Histidine kinase
AZK53_19680	COG2201	protein-glutamate methylesterase activity
AZK53_19685	COG0455	bacterial-type flagellum organization
AZK53_19690	COG1419	protein localization to endoplasmic reticulum
AZK53_19695	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZK53_19700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AZK53_19705	COG1684	flagellar biosynthetic protein fliR
AZK53_19710	COG1987	bacterial-type flagellum assembly
AZK53_19715	COG1338	Plays a role in the flagellum-specific transport system
AZK53_19720	COG3190	flagellar
AZK53_19725	COG2201	protein-glutamate methylesterase activity
AZK53_19730	COG1776	CheC inhibitor of MCP methylation
AZK53_19730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZK53_19735	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZK53_19745	COG1582	Flagellar protein (FlbD)
AZK53_19750	COG4786	Flagellar basal body rod
AZK53_19755	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AZK53_19770	COG2882	bacterial-type flagellum organization
AZK53_19775	COG1157	protein secretion by the type III secretion system
AZK53_19780	COG1317	bacterial-type flagellum organization
AZK53_19785	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AZK53_19790	COG1766	The M ring may be actively involved in energy transduction
AZK53_19795	COG1677	Flagellar hook-basal body complex protein FliE
AZK53_19800	COG1558	bacterial-type flagellum-dependent cell motility
AZK53_19805	COG1815	bacterial-type flagellum-dependent cell motility
AZK53_19810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AZK53_19815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AZK53_19825	COG4974	Belongs to the 'phage' integrase family
AZK53_19835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AZK53_19840	COG0758	DNA mediated transformation
AZK53_19845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AZK53_19850	COG0045	succinate-CoA ligase (ADP-forming) activity
AZK53_19870	COG0335	large ribosomal subunit rRNA binding
AZK53_19880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AZK53_19890	COG1837	Belongs to the UPF0109 family
AZK53_19895	COG0228	four-way junction DNA binding
AZK53_19900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZK53_19910	COG0552	protein localization to endoplasmic reticulum
AZK53_19915	COG1196	nuclear chromosome segregation
AZK53_19925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AZK53_19930	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_19935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AZK53_19940	COG0416	fatty acid biosynthetic process
AZK53_19945	COG1349	DNA-binding transcription factor activity
AZK53_19950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AZK53_19955	COG1760	l-serine dehydratase
AZK53_19960	COG1760	l-serine dehydratase
AZK53_19970	COG1461	Dihydroxyacetone kinase
AZK53_19975	COG1302	Protein conserved in bacteria
AZK53_19980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AZK53_19990	COG1564	THIamine pyrophosphokinase
AZK53_19995	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AZK53_20000	COG1162	GTPase activity
AZK53_20005	COG0515	serine threonine protein kinase
AZK53_20005	COG2815	serine threonine protein kinase
AZK53_20010	COG0631	protein serine/threonine phosphatase activity
AZK53_20020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZK53_20020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AZK53_20025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AZK53_20035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AZK53_20040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AZK53_20045	COG1758	RNA polymerase activity
AZK53_20050	COG0194	GDP metabolic process
AZK53_20055	COG2052	Domain of unknown function (DUF370)
AZK53_20060	COG1561	YicC-like family, N-terminal region
AZK53_20065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AZK53_20075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AZK53_20105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AZK53_20120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AZK53_20125	COG0564	pseudouridine synthase activity
AZK53_20130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AZK53_20145	COG3599	regulation of cell shape
AZK53_20150	COG2302	S4 RNA-binding domain
AZK53_20155	COG0762	integral membrane protein
AZK53_20160	COG1799	cell septum assembly
AZK53_20165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AZK53_20175	COG1873	PFAM PRC-barrel domain
AZK53_20180	COG1191	sigma factor activity
AZK53_20185	COG1191	sigma factor activity
AZK53_20195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AZK53_20200	COG0849	cell division
AZK53_20205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AZK53_20210	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AZK53_20215	COG0772	Belongs to the SEDS family
AZK53_20220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AZK53_20225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZK53_20230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AZK53_20235	COG0768	penicillin binding
AZK53_20245	COG4839	cell division protein FtsL
AZK53_20255	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AZK53_20265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AZK53_20270	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZK53_20275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AZK53_20280	COG0439	Biotin carboxylase
AZK53_20285	COG0454	-acetyltransferase
AZK53_20295	COG1024	Enoyl-CoA hydratase
AZK53_20300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AZK53_20305	COG1399	metal-binding, possibly nucleic acid-binding protein
AZK53_20310	COG1323	Belongs to the UPF0348 family
AZK53_20315	COG3480	Lon protease (S16) C-terminal proteolytic domain
AZK53_20325	COG3314	Sporulation integral membrane protein YlbJ
AZK53_20330	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AZK53_20335	COG0742	ribosomal rna small subunit methyltransferase
AZK53_20345	COG4471	UPF0298 protein
AZK53_20355	COG3679	Belongs to the UPF0342 family
AZK53_20375	COG4347	Protein of unknown function (DUF1405)
AZK53_20385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AZK53_20400	COG5582	Belongs to the UPF0302 family
AZK53_20405	COG0457	Tetratricopeptide repeat
AZK53_20410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AZK53_20415	COG0287	Prephenate dehydrogenase
AZK53_20420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AZK53_20425	COG0159	tryptophan synthase activity
AZK53_20435	COG0135	phosphoribosylanthranilate isomerase activity
AZK53_20440	COG0134	indole-3-glycerol-phosphate synthase activity
AZK53_20445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AZK53_20455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AZK53_20460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AZK53_20465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AZK53_20470	COG0105	UTP biosynthetic process
AZK53_20475	COG0142	geranyltranstransferase activity
AZK53_20480	COG2226	methyltransferase
AZK53_20485	COG0142	geranyltranstransferase activity
AZK53_20495	COG0302	gtp cyclohydrolase
AZK53_20500	COG0776	regulation of translation
AZK53_20505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AZK53_20535	COG2271	Major facilitator Superfamily
AZK53_20540	COG1304	FMN binding
AZK53_20545	COG0539	negative regulation of cytoplasmic translation
AZK53_20555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AZK53_20565	COG2959	enzyme of heme biosynthesis
AZK53_20570	COG3773	Cell wall hydrolase
AZK53_20570	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_20575	COG2339	peptidase activity
AZK53_20580	COG0252	asparaginase activity
AZK53_20585	COG0492	ferredoxin-NADP+ reductase activity
AZK53_20590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AZK53_20595	COG4862	establishment of competence for transformation
AZK53_20600	COG0789	Transcriptional regulator
AZK53_20605	COG1408	metallophosphoesterase
AZK53_20620	COG1266	CAAX protease self-immunity
AZK53_20625	COG0514	ATP-dependent DNA helicase (RecQ)
AZK53_20635	COG1141	Ferredoxin
AZK53_20640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AZK53_20645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AZK53_20650	COG0739	heme binding
AZK53_20655	COG5002	protein histidine kinase activity
AZK53_20660	COG0745	RESPONSE REGULATOR receiver
AZK53_20665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZK53_20670	COG1333	cytochrome c biogenesis protein
AZK53_20675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_20680	COG1187	pseudouridine synthase activity
AZK53_20685	COG0700	Nucleoside recognition
AZK53_20690	COG2715	membrane protein required for spore maturation
AZK53_20695	COG1686	Belongs to the peptidase S11 family
AZK53_20700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AZK53_20705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AZK53_20710	COG1547	Domain of unknown function (DUF309)
AZK53_20720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AZK53_20725	COG4086	secreted protein
AZK53_20735	COG0697	spore germination
AZK53_20750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AZK53_20785	COG1686	Belongs to the peptidase S11 family
AZK53_20800	COG4974	Belongs to the 'phage' integrase family
AZK53_20810	COG0735	belongs to the Fur family
AZK53_20815	COG1300	Membrane
AZK53_20820	COG0494	nUDIX hydrolase
AZK53_20830	COG0667	Aldo Keto reductase
AZK53_20840	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AZK53_20845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AZK53_20855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZK53_20860	COG1073	alpha beta
AZK53_20875	COG0300	oxidoreductase activity
AZK53_20880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_20885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZK53_20890	COG1902	pentaerythritol trinitrate reductase activity
AZK53_20895	COG1234	tRNA 3'-trailer cleavage
AZK53_20900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AZK53_20905	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_20910	COG2508	Transcriptional regulator
AZK53_20930	COG0167	dihydroorotate dehydrogenase activity
AZK53_20930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AZK53_20935	COG0493	'glutamate synthase
AZK53_20940	COG2195	Cleaves the N-terminal amino acid of tripeptides
AZK53_20945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AZK53_20950	COG0346	lactoylglutathione lyase activity
AZK53_20955	COG1376	ErfK ybiS ycfS ynhG family protein
AZK53_20960	COG4129	membrane
AZK53_20965	COG1126	abc transporter atp-binding protein
AZK53_20970	COG0765	amino acid transport
AZK53_20975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AZK53_20985	COG1703	isobutyryl-CoA mutase activity
AZK53_20990	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_20990	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_21000	COG0508	dehydrogenase complex catalyzes the overall conversion of
AZK53_21005	COG0022	dehydrogenase e1 component
AZK53_21010	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AZK53_21015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AZK53_21030	COG0280	phosphate acetyltransferase
AZK53_21035	COG3829	transcription factor binding
AZK53_21035	COG3290	protein histidine kinase activity
AZK53_21045	COG0584	glycerophosphoryl diester phosphodiesterase
AZK53_21050	COG3104	oligopeptide transport
AZK53_21055	COG0745	RESPONSE REGULATOR receiver
AZK53_21060	COG0750	zinc metalloprotease
AZK53_21065	COG0497	DNA recombination
AZK53_21075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AZK53_21090	COG1722	exodeoxyribonuclease VII activity
AZK53_21100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AZK53_21105	COG1302	Protein conserved in bacteria
AZK53_21110	COG0439	Biotin carboxylase
AZK53_21115	COG0511	ligase activity, forming carbon-carbon bonds
AZK53_21155	COG3854	ATPases associated with a variety of cellular activities
AZK53_21165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AZK53_21170	COG0006	proline dipeptidase activity
AZK53_21175	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AZK53_21185	COG3872	metal-dependent enzyme
AZK53_21195	COG1752	Esterase of the alpha-beta hydrolase superfamily
AZK53_21200	COG1321	iron dependent repressor
AZK53_21215	COG0095	Lipoate-protein ligase
AZK53_21220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_21230	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZK53_21235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AZK53_21240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZK53_21270	COG4970	Tfp pilus assembly protein FimT
AZK53_21275	COG4537	Required for transformation and DNA binding
AZK53_21280	COG1459	type II secretion system
AZK53_21285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AZK53_21290	COG1393	Belongs to the ArsC family
AZK53_21300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_21310	COG1940	carbohydrate kinase activity
AZK53_21315	COG4483	Protein conserved in bacteria
AZK53_21320	COG0457	Tetratricopeptide repeat
AZK53_21320	COG0705	Rhomboid family
AZK53_21330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AZK53_21340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AZK53_21355	COG0704	Plays a role in the regulation of phosphate uptake
AZK53_21370	COG0477	Major facilitator Superfamily
AZK53_21405	COG2839	Protein conserved in bacteria
AZK53_21415	COG2814	Major facilitator Superfamily
AZK53_21420	COG1388	LysM domain
AZK53_21425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AZK53_21430	COG4709	membrane
AZK53_21435	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
AZK53_21440	COG0735	belongs to the Fur family
AZK53_21445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AZK53_21450	COG1121	(ABC) transporter
AZK53_21460	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AZK53_21465	COG0513	Belongs to the DEAD box helicase family
AZK53_21475	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AZK53_21480	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AZK53_21485	COG2384	SAM-dependent methyltransferase
AZK53_21490	COG2010	Cytochrome c
AZK53_21500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AZK53_21505	COG0358	DNA primase activity
AZK53_21510	COG1671	Belongs to the UPF0178 family
AZK53_21515	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AZK53_21520	COG0517	IMP dehydrogenase activity
AZK53_21530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AZK53_21535	COG0295	cytidine deaminase activity
AZK53_21540	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AZK53_21550	COG1480	7TM receptor with intracellular HD hydrolase
AZK53_21555	COG1702	phosphate starvation-inducible protein PhoH
AZK53_21580	COG1030	water channel activity
AZK53_21585	COG1610	YqeY-like protein
AZK53_21590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AZK53_21595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AZK53_21600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AZK53_21605	COG2264	protein methyltransferase activity
AZK53_21620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZK53_21625	COG1420	regulation of RNA biosynthetic process
AZK53_21630	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AZK53_21635	COG0481	GTPase activity
AZK53_21645	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AZK53_21650	COG0268	Binds directly to 16S ribosomal RNA
AZK53_21655	COG1466	dna polymerase III delta subunit
AZK53_21660	COG0658	competence protein
AZK53_21660	COG2333	competence protein COMEC
AZK53_21665	COG2131	deaminase
AZK53_21670	COG1555	photosystem II stabilization
AZK53_21670	COG1596	polysaccharide export
AZK53_21675	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AZK53_21680	COG2226	methyltransferase
AZK53_21685	COG0799	negative regulation of ribosome biogenesis
AZK53_21690	COG1713	HD superfamily hydrolase involved in NAD metabolism
AZK53_21695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AZK53_21700	COG1534	Rna-binding protein
AZK53_21705	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AZK53_21710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AZK53_21715	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AZK53_21725	COG0688	phosphatidylethanolamine metabolic process
AZK53_21730	COG1183	phosphatidylcholine synthase activity
AZK53_21735	COG1191	sigma factor activity
AZK53_21745	COG0626	cystathionine gamma-synthase activity
AZK53_21750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZK53_21755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AZK53_21760	COG2226	methyltransferase
AZK53_21775	COG0768	penicillin binding
AZK53_21780	COG1335	isochorismatase
AZK53_21785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AZK53_21790	COG0572	uridine kinase
AZK53_21810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AZK53_21815	COG3906	Belongs to the UPF0473 family
AZK53_21825	COG4472	Bacterial protein of unknown function (DUF965)
AZK53_21835	COG0628	permease
AZK53_21845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AZK53_21855	COG0482	sulfurtransferase activity
AZK53_21860	COG1104	cysteine desulfurase activity
AZK53_21865	COG1959	2 iron, 2 sulfur cluster binding
AZK53_21870	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AZK53_21875	COG0581	inorganic phosphate transmembrane transporter activity
AZK53_21880	COG0573	inorganic phosphate transmembrane transporter activity
AZK53_21885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AZK53_21890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AZK53_21900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AZK53_21905	COG0124	histidyl-tRNA synthetase
AZK53_21915	COG0860	N-Acetylmuramoyl-L-alanine amidase
AZK53_21920	COG1490	D-aminoacyl-tRNA deacylase activity
AZK53_21925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AZK53_21930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AZK53_21935	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AZK53_21935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AZK53_21940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZK53_21940	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AZK53_21950	COG2244	polysaccharide biosynthetic process
AZK53_21955	COG2323	membrane
AZK53_21965	COG1862	Preprotein translocase
AZK53_21975	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AZK53_21985	COG2255	four-way junction helicase activity
AZK53_22015	COG1388	LysM domain
AZK53_22020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AZK53_22025	COG0157	Belongs to the NadC ModD family
AZK53_22030	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AZK53_22035	COG1104	cysteine desulfurase activity
AZK53_22040	COG1827	regulation of RNA biosynthetic process
AZK53_22045	COG0077	Prephenate dehydratase
AZK53_22050	COG4492	Belongs to the UPF0735 family
AZK53_22055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZK53_22060	COG3290	protein histidine kinase activity
AZK53_22070	COG2868	ribosomal protein
AZK53_22080	COG1530	ribonuclease E activity
AZK53_22085	COG1994	Peptidase M50
AZK53_22090	COG0739	heme binding
AZK53_22095	COG2894	cell division
AZK53_22100	COG0850	regulation of cytokinetic process
AZK53_22105	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AZK53_22110	COG1792	Involved in formation and maintenance of cell shape
AZK53_22115	COG1077	Cell shape determining protein MreB Mrl
AZK53_22120	COG2003	Belongs to the UPF0758 family
AZK53_22125	COG0424	maF-like protein
AZK53_22135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AZK53_22145	COG2322	membrane
AZK53_22150	COG0285	dihydrofolate synthase activity
AZK53_22155	COG0525	valine-tRNA ligase activity
AZK53_22165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZK53_22170	COG1388	LysM domain
AZK53_22175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AZK53_22180	COG0113	porphobilinogen synthase activity
AZK53_22185	COG1587	Uroporphyrinogen-III synthase
AZK53_22190	COG0181	hydroxymethylbilane synthase activity
AZK53_22195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AZK53_22210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AZK53_22215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AZK53_22220	COG1067	ATP-dependent peptidase activity
AZK53_22220	COG0470	DNA polymerase III
AZK53_22225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AZK53_22230	COG0544	peptidyl-prolyl cis-trans isomerase activity
AZK53_22235	COG0457	Tetratricopeptide repeat
AZK53_22235	COG1477	protein flavinylation
AZK53_22240	COG0066	3-isopropylmalate dehydratase activity
AZK53_22245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AZK53_22255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AZK53_22260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AZK53_22265	COG0440	acetolactate synthase activity
AZK53_22270	COG0028	Belongs to the TPP enzyme family
AZK53_22280	COG0622	Phosphoesterase
AZK53_22295	COG5401	PFAM Sporulation and spore germination
AZK53_22300	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AZK53_22305	COG1846	Transcriptional regulator
AZK53_22315	COG0306	phosphate transporter
AZK53_22320	COG1392	Phosphate transport regulator
AZK53_22325	COG0768	penicillin binding
AZK53_22335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AZK53_22340	COG0431	NADPH-dependent FMN reductase
AZK53_22345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_22350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZK53_22355	COG1116	anion transmembrane transporter activity
AZK53_22360	COG0475	glutathione-regulated potassium exporter activity
AZK53_22365	COG0490	domain, Protein
AZK53_22375	COG2197	response regulator
AZK53_22380	COG0824	Thioesterase
AZK53_22385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AZK53_22390	COG1053	succinate dehydrogenase
AZK53_22395	COG2009	succinate dehydrogenase
AZK53_22400	COG1719	4-vinyl reductase, 4VR
AZK53_22405	COG0527	aspartate kinase activity
AZK53_22415	COG3118	belongs to the thioredoxin family
AZK53_22420	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AZK53_22425	COG2086	electron transfer activity
AZK53_22430	COG1024	Enoyl-CoA hydratase
AZK53_22435	COG1309	transcriptional regulator
AZK53_22440	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_22445	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AZK53_22450	COG3766	membrane
AZK53_22455	COG1193	negative regulation of DNA recombination
AZK53_22460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZK53_22460	COG1796	DNA polymerase
AZK53_22465	COG1286	toxin biosynthetic process
AZK53_22470	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AZK53_22475	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AZK53_22480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZK53_22480	COG0072	phenylalanine-tRNA ligase activity
AZK53_22490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AZK53_22500	COG1363	Peptidase, m42
AZK53_22520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AZK53_22525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AZK53_22530	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AZK53_22535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AZK53_22550	COG1484	DNA-dependent DNA replication
AZK53_22555	COG3611	Membrane attachment protein
AZK53_22560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AZK53_22570	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AZK53_22575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AZK53_22580	COG0237	dephospho-CoA kinase activity
AZK53_22585	COG1971	Probably functions as a manganese efflux pump
AZK53_22590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AZK53_22595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZK53_22595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AZK53_22600	COG5002	protein histidine kinase activity
AZK53_22605	COG0745	RESPONSE REGULATOR receiver
AZK53_22615	COG0039	L-malate dehydrogenase activity
AZK53_22620	COG0538	isocitrate dehydrogenase activity
AZK53_22625	COG0372	Belongs to the citrate synthase family
AZK53_22630	COG2707	UPF0756 membrane protein
AZK53_22635	COG0628	permease
AZK53_22640	COG3030	protein affecting phage T7 exclusion by the F plasmid
AZK53_22650	COG0825	malonyl-CoA metabolic process
AZK53_22655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AZK53_22660	COG2186	Transcriptional regulator
AZK53_22665	COG0281	malic enzyme
AZK53_22670	COG0587	DNA-directed DNA polymerase activity
AZK53_22685	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AZK53_22695	COG4109	DRTGG domain
AZK53_22705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AZK53_22715	COG0165	Argininosuccinate lyase
AZK53_22720	COG0137	argininosuccinate synthase activity
AZK53_22735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AZK53_22740	COG0827	DNA restriction-modification system
AZK53_22745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AZK53_22750	COG3874	Sporulation protein YtfJ
AZK53_22760	COG1714	RDD family
AZK53_22765	COG0616	signal peptide processing
AZK53_22770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AZK53_22775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AZK53_22785	COG0301	tRNA thio-modification
AZK53_22790	COG1104	cysteine desulfurase activity
AZK53_22795	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AZK53_22800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AZK53_22805	COG1309	transcriptional regulator
AZK53_22810	COG1956	GAF domain-containing protein
AZK53_22820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AZK53_22825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AZK53_22830	COG0454	-acetyltransferase
AZK53_22835	COG0517	IMP dehydrogenase activity
AZK53_22840	COG0123	including yeast histone deacetylase and acetoin utilization protein
AZK53_22860	COG1605	Chorismate mutase
AZK53_22860	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AZK53_22865	COG3118	belongs to the thioredoxin family
AZK53_22870	COG4980	gas vesicle protein
AZK53_22885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AZK53_22895	COG1674	ftsk spoiiie
AZK53_22900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AZK53_22905	COG4848	Belongs to the UPF0354 family
AZK53_22910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_22915	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AZK53_22920	COG1363	Peptidase, m42
AZK53_22925	COG5584	Small secreted protein
AZK53_22930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AZK53_22935	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AZK53_22945	COG0510	thiamine kinase activity
AZK53_22950	COG1523	belongs to the glycosyl hydrolase 13 family
AZK53_22960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AZK53_22965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AZK53_22970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AZK53_22975	COG1349	DNA-binding transcription factor activity
AZK53_22980	COG1187	pseudouridine synthase activity
AZK53_22985	COG2244	polysaccharide biosynthetic process
AZK53_22990	COG2081	HI0933 family
AZK53_23000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AZK53_23005	COG0495	leucyl-tRNA aminoacylation
AZK53_23015	COG2610	gluconate transmembrane transporter activity
AZK53_23020	COG2814	Major facilitator Superfamily
AZK53_23035	COG1242	4 iron, 4 sulfur cluster binding
AZK53_23040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AZK53_23050	COG2267	carboxylic ester hydrolase activity
AZK53_23055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AZK53_23060	COG0671	phosphoesterase, PA-phosphatase related
AZK53_23065	COG0438	transferase activity, transferring glycosyl groups
AZK53_23070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AZK53_23075	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AZK53_23085	COG1506	peptidase
AZK53_23090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AZK53_23095	COG1116	anion transmembrane transporter activity
AZK53_23100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AZK53_23105	COG0494	nUDIX hydrolase
AZK53_23115	COG4824	toxin secretion phage lysis holin
AZK53_23120	COG0783	Belongs to the Dps family
AZK53_23130	COG0288	reversible hydration of carbon dioxide
AZK53_23135	COG0523	cobalamin synthesis protein
AZK53_23145	COG0254	rRNA binding
AZK53_23150	COG1271	oxidase subunit
AZK53_23155	COG1294	oxidase, subunit
AZK53_23160	COG0716	FMN binding
AZK53_23180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZK53_23185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AZK53_23190	COG4948	Mandelate Racemase Muconate Lactonizing
AZK53_23195	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_23200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AZK53_23205	COG0596	Alpha beta hydrolase
AZK53_23210	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AZK53_23215	COG1169	isochorismate synthase
AZK53_23220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZK53_23230	COG0058	SHG alpha-glucan phosphorylase activity
AZK53_23235	COG0297	glycogen (starch) synthase activity
AZK53_23240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AZK53_23375	COG0318	PFAM AMP-dependent synthetase and ligase
AZK53_23380	COG1285	pathogenesis
AZK53_23400	COG0529	Catalyzes the synthesis of activated sulfate
AZK53_23410	COG0306	phosphate transporter
AZK53_23420	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AZK53_23425	COG0346	lactoylglutathione lyase activity
AZK53_23430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AZK53_23440	COG0166	Belongs to the GPI family
AZK53_23450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AZK53_23450	COG2111	Na H antiporter
AZK53_23455	COG2111	Na H antiporter
AZK53_23460	COG1006	Multisubunit Na H antiporter MnhC subunit
AZK53_23465	COG0651	ATP synthesis coupled electron transport
AZK53_23470	COG1863	multisubunit Na H antiporter MnhE subunit
AZK53_23475	COG2212	antiporter activity
AZK53_23480	COG1320	monovalent cation:proton antiporter activity
AZK53_23485	COG1979	alcohol dehydrogenase
AZK53_23490	COG2155	Conserved Protein
AZK53_23495	COG1098	S1 RNA binding domain
AZK53_23500	COG0436	Aminotransferase
AZK53_23505	COG1522	sequence-specific DNA binding
AZK53_23510	COG2267	carboxylic ester hydrolase activity
AZK53_23515	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AZK53_23520	COG2032	superoxide dismutase activity
AZK53_23535	COG5018	Exonuclease
AZK53_23540	COG2050	protein possibly involved in aromatic compounds catabolism
AZK53_23550	COG1418	mRNA catabolic process
AZK53_23560	COG2056	Na+-H+ antiporter family
AZK53_23565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AZK53_23570	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
AZK53_23575	COG3584	3D domain protein
AZK53_23585	COG1252	NADH dehydrogenase
AZK53_23590	COG0492	ferredoxin-NADP+ reductase activity
AZK53_23600	COG0316	Belongs to the HesB IscA family
AZK53_23605	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AZK53_23615	COG4844	belongs to the
AZK53_23620	COG1252	NADH dehydrogenase
AZK53_23625	COG4837	Protein of unknown function (DUF1462)
AZK53_23630	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AZK53_23635	COG0083	homoserine kinase activity
AZK53_23640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AZK53_23645	COG0460	homoserine dehydrogenase
AZK53_23650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AZK53_23655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AZK53_23660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AZK53_23665	COG0647	UMP catabolic process
AZK53_23670	COG2445	Protein of unknown function DUF86
AZK53_23680	COG4470	Protein conserved in bacteria
AZK53_23690	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AZK53_23695	COG0739	heme binding
AZK53_23700	COG0733	neurotransmitter:sodium symporter activity
AZK53_23710	COG3377	Domain of unknown function (DUF1805)
AZK53_23715	COG1801	Protein of unknown function DUF72
AZK53_23720	COG0719	Fe-S assembly protein
AZK53_23725	COG0822	iron-sulfur transferase activity
AZK53_23730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AZK53_23735	COG0719	Fe-S assembly protein
AZK53_23740	COG0396	ATPase activity
AZK53_23745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AZK53_23750	COG1464	Belongs to the NlpA lipoprotein family
AZK53_23755	COG2011	ABC-type metal ion transport system permease component
AZK53_23760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AZK53_23765	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AZK53_23770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AZK53_23780	COG0509	glycine decarboxylation via glycine cleavage system
AZK53_23785	COG1393	Belongs to the ArsC family
AZK53_23790	COG1960	acyl-CoA dehydrogenase activity
AZK53_23795	COG0183	Belongs to the thiolase family
AZK53_23800	COG1024	Enoyl-CoA hydratase
AZK53_23800	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZK53_23820	COG1120	ATPase activity
AZK53_23825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_23830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AZK53_23835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AZK53_23840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AZK53_23845	COG1309	transcriptional regulator
AZK53_23855	COG1028	Short-chain dehydrogenase reductase Sdr
AZK53_23860	COG0477	Major facilitator Superfamily
AZK53_23870	COG5002	protein histidine kinase activity
AZK53_23870	COG3850	Histidine kinase
AZK53_23875	COG0745	RESPONSE REGULATOR receiver
AZK53_23880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AZK53_23885	COG0671	phosphoesterase, PA-phosphatase related
AZK53_23890	COG1846	Transcriptional regulator
AZK53_23895	COG0778	Nitroreductase
AZK53_23900	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AZK53_23905	COG0314	molybdopterin synthase activity
AZK53_23910	COG1763	Mo-molybdopterin cofactor biosynthetic process
AZK53_23915	COG0303	'Molybdopterin
AZK53_23920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AZK53_23925	COG0746	molybdenum cofactor guanylyltransferase activity
AZK53_23935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AZK53_23940	COG5609	conserved protein (DUF2294)
AZK53_23945	COG3383	formate dehydrogenase (NAD+) activity
AZK53_23950	COG2427	Protein of unknown function (DUF1641)
AZK53_23955	COG0725	ABC transporter, periplasmic molybdate-binding protein
AZK53_23960	COG4149	molybdate abc transporter
AZK53_23970	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AZK53_23975	COG0557	exoribonuclease II activity
AZK53_23980	COG1647	Serine aminopeptidase, S33
AZK53_23985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AZK53_23995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AZK53_24025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AZK53_24045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AZK53_24055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AZK53_24060	COG1660	Displays ATPase and GTPase activities
AZK53_24065	COG1051	belongs to the nudix hydrolase family
AZK53_24070	COG0492	ferredoxin-NADP+ reductase activity
AZK53_24075	COG0457	Tetratricopeptide repeat
AZK53_24080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AZK53_24080	COG0140	phosphoribosyl-ATP diphosphatase activity
AZK53_24085	COG0107	imidazoleglycerol-phosphate synthase activity
AZK53_24090	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AZK53_24095	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AZK53_24100	COG0131	Imidazoleglycerol-phosphate dehydratase
AZK53_24105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AZK53_24110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AZK53_24115	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AZK53_24120	COG0110	maltose O-acetyltransferase activity
AZK53_24125	COG0546	phosphoglycolate phosphatase activity
AZK53_24130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AZK53_24135	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AZK53_24140	COG1950	PFAM Membrane protein of
AZK53_24145	COG1983	PspC domain protein
AZK53_24150	COG3595	metallopeptidase activity
AZK53_24160	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AZK53_24165	COG0556	nucleotide-excision repair
AZK53_24170	COG2204	response regulator
AZK53_24175	COG1012	belongs to the aldehyde dehydrogenase family
AZK53_24180	COG0506	proline dehydrogenase activity
AZK53_24185	COG4897	Protein conserved in bacteria
AZK53_24190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZK53_24195	COG0793	Belongs to the peptidase S41A family
AZK53_24195	COG3409	Peptidoglycan-binding domain 1 protein
AZK53_24200	COG0739	heme binding
AZK53_24205	COG2177	Part of the ABC transporter FtsEX involved in
AZK53_24210	COG2884	Cell division ATP-binding protein ftsE
AZK53_24215	COG0655	NAD(P)H dehydrogenase (quinone) activity
AZK53_24225	COG0805	protein transport
AZK53_24230	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AZK53_24235	COG3540	Alkaline phosphatase
AZK53_24240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AZK53_24245	COG0653	protein targeting
AZK53_24250	COG0456	acetyltransferase
AZK53_24255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AZK53_24265	COG1516	flagellar protein fliS
AZK53_24270	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AZK53_24280	COG1113	amino acid transport
AZK53_24295	COG1454	alcohol dehydrogenase
AZK53_24300	COG1510	regulation of RNA biosynthetic process
AZK53_24305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AZK53_24310	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AZK53_24315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AZK53_24320	COG4786	Flagellar basal body rod
AZK53_24320	COG1256	bacterial-type flagellum assembly
AZK53_24340	COG1040	competence protein
AZK53_24345	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AZK53_24350	COG1307	EDD domain protein, DegV family
AZK53_24355	COG1728	Protein conserved in bacteria
AZK53_24365	COG2197	response regulator
AZK53_24370	COG4585	Histidine kinase
AZK53_24375	COG1739	Uncharacterized protein family UPF0029
AZK53_24380	COG1316	TRANSCRIPTIONal
AZK53_24385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AZK53_24390	COG1585	Membrane protein implicated in regulation of membrane protease activity
AZK53_24395	COG2268	Band 7 protein
AZK53_24400	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AZK53_24410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AZK53_24420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AZK53_24425	COG1388	LysM domain
AZK53_24425	COG0791	NLP P60 protein
AZK53_24430	COG0629	single-stranded DNA binding
AZK53_24455	COG4786	Flagellar basal body rod
AZK53_24460	COG4786	Flagellar basal body rod
AZK53_24465	COG1077	Cell shape determining protein MreB Mrl
AZK53_24470	COG1609	Transcriptional regulator
AZK53_24475	COG0739	heme binding
AZK53_24480	COG2385	sporulation resulting in formation of a cellular spore
AZK53_24495	COG4836	Membrane
AZK53_24500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AZK53_24505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AZK53_24510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AZK53_24515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AZK53_24520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZK53_24525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AZK53_24530	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AZK53_24535	COG0356	it plays a direct role in the translocation of protons across the membrane
AZK53_24550	COG1404	Belongs to the peptidase S8 family
AZK53_24555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AZK53_24560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AZK53_24575	COG0698	ribose 5-phosphate isomerase
AZK53_24585	COG1971	Probably functions as a manganese efflux pump
AZK53_24590	COG0009	L-threonylcarbamoyladenylate synthase
AZK53_24610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AZK53_24625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AZK53_24635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AZK53_24640	COG0191	fructose-bisphosphate aldolase activity
AZK53_24645	COG2204	response regulator
AZK53_24650	COG4821	SIS domain
AZK53_24655	COG0504	CTP synthase activity
AZK53_24665	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_24665	COG1703	isobutyryl-CoA mutase activity
AZK53_24665	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AZK53_24675	COG1960	acyl-CoA dehydrogenase activity
AZK53_24680	COG1960	acyl-CoA dehydrogenase activity
AZK53_24685	COG1250	3-hydroxyacyl-CoA dehydrogenase
AZK53_24695	COG0247	lactate metabolic process
AZK53_24695	COG2181	nitrate reductase activity
AZK53_24700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AZK53_24715	COG4506	Protein conserved in bacteria
AZK53_24720	COG0010	Belongs to the arginase family
AZK53_24725	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AZK53_24730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AZK53_24740	COG1994	Peptidase M50
AZK53_24745	COG1942	4-Oxalocrotonate Tautomerase
AZK53_24750	COG3465	dGTPase activity
AZK53_24755	COG1078	dGTPase activity
AZK53_24760	COG4844	belongs to the
AZK53_24770	COG0095	Lipoate-protein ligase
AZK53_24775	COG0280	phosphate acetyltransferase
AZK53_24785	COG3773	Cell wall hydrolase
AZK53_24795	COG2363	Small membrane protein
AZK53_24805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AZK53_24815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AZK53_24820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AZK53_24825	COG2508	Transcriptional regulator
AZK53_24825	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AZK53_24830	COG0686	Belongs to the AlaDH PNT family
AZK53_24840	COG0351	phosphomethylpyrimidine kinase
AZK53_24845	COG0561	phosphatase activity
AZK53_24850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AZK53_24855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AZK53_24855	COG2190	(PTS) system
AZK53_24855	COG1263	PTS System
AZK53_24865	COG0438	transferase activity, transferring glycosyl groups
AZK53_24880	COG2076	Multidrug Resistance protein
AZK53_24890	COG0728	peptidoglycan biosynthetic process
AZK53_24905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AZK53_24910	COG4988	ABC transporter
AZK53_24915	COG1294	oxidase, subunit
AZK53_24920	COG1271	oxidase subunit
AZK53_24925	COG3610	response to peptide
AZK53_24930	COG2966	Psort location CytoplasmicMembrane, score
AZK53_24935	COG1609	Transcriptional regulator
AZK53_24945	COG2814	Major facilitator Superfamily
AZK53_24960	COG1966	Carbon starvation protein
AZK53_24965	COG0753	catalase activity
AZK53_24975	COG0471	metal ion transport
AZK53_24980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AZK53_24990	COG0745	RESPONSE REGULATOR receiver
AZK53_24995	COG5002	protein histidine kinase activity
AZK53_25010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AZK53_25015	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AZK53_25020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AZK53_25025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AZK53_25030	COG4853	Protein conserved in bacteria
AZK53_25040	COG5002	protein histidine kinase activity
AZK53_25045	COG0745	RESPONSE REGULATOR receiver
AZK53_25070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AZK53_25075	COG0305	Participates in initiation and elongation during chromosome replication
AZK53_25085	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
AZK53_25095	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AZK53_25110	COG0012	GTP binding
AZK53_25115	COG4481	Protein conserved in bacteria
AZK53_25120	COG0668	transmembrane transport
AZK53_25125	COG3949	Membrane
AZK53_25135	COG1475	DNA binding
AZK53_25140	COG1192	Involved in chromosome partitioning
AZK53_25145	COG1475	DNA binding
AZK53_25155	COG0445	tRNA wobble uridine modification
AZK53_25160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AZK53_25165	COG1847	R3H domain protein
AZK53_25170	COG0706	membrane insertase activity
AZK53_25175	COG0594	ribonuclease P activity
AZK53_25180	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AZK53_25185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AZK53_25190	COG0592	DNA-directed DNA polymerase activity
AZK53_25195	COG2501	S4 domain
AZK53_25200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AZK53_25205	COG0187	DNA topoisomerase II activity
AZK53_25210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AZK53_25245	COG0517	IMP dehydrogenase activity
AZK53_25245	COG0516	GMP reductase activity
AZK53_25260	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AZK53_25275	COG1428	Deoxynucleoside kinase
AZK53_25280	COG1428	Deoxynucleoside kinase
AZK53_25285	COG3858	chitin binding
AZK53_25285	COG1388	LysM domain
AZK53_25290	COG1335	isochorismatase
AZK53_25295	COG0590	tRNA wobble adenosine to inosine editing
AZK53_25305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AZK53_25310	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AZK53_25315	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AZK53_25420	COG1982	Orn Lys Arg decarboxylase major