locus-tag class description MY9_0001 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) MY9_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) MY9_0003 ENOG410848D S4 domain protein YaaA MY9_0006 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) MY9_0007 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) MY9_0009 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) MY9_0011 ENOG4105CD9 Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity) MY9_0012 ENOG4108UHX Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity) MY9_0013 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) MY9_0014 ENOG4105ZMH deoxynucleoside kinase MY9_0016 ENOG4105VRS hydrolase family 18 MY9_0017 ENOG4105GTG Isochorismatase MY9_0018 ENOG4108Z6B deaminase MY9_0019 ENOG4105C6E dna polymerase iii MY9_0020 ENOG410816I Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) MY9_0021 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) MY9_0023 ENOG41067KS pro-sigma K processing MY9_0026 ENOG4105CDW Resistance protein MY9_0027 ENOG4105CXN decarboxylase MY9_0028 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) MY9_0029 ENOG4105X0R protein from nitrogen regulatory protein P-II MY9_0030 ENOG4105XVJ Protein of unknown function (DUF327) MY9_0031 ENOG4105FA2 dna polymerase iii MY9_0032 ENOG4105MA4 psp1 domain protein MY9_0033 ENOG4105QD5 Involved in initiation control of chromosome replication (By similarity) MY9_0034 ENOG41060K3 Methyltransferase MY9_0035 ENOG4105VC4 domain protein MY9_0036 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) MY9_0037 ENOG4105KRN Transcriptional regulator, abrb family MY9_0038 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) MY9_0039 ENOG4105F8V Hydrolase, tatD family MY9_0040 ENOG41069ER domain protein MY9_0042 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) MY9_0043 ENOG4105W42 Veg protein MY9_0044 ENOG4105XEW small acid-soluble spore protein MY9_0045 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) MY9_0046 ENOG4105DFT pur operon repressor MY9_0047 ENOG4105KME endoribonuclease L-psp MY9_0048 ENOG4105K4W Could be involved in septation (By similarity) MY9_0050 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) MY9_0051 ENOG4105C5T Phosphoribosyl pyrophosphate synthase MY9_0052 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) MY9_0054 ENOG4108JA2 transcriptioN-repair coupling factor MY9_0055 ENOG4108M14 stage v sporulation protein t MY9_0057 ENOG4108IY2 MazG family MY9_0058 ENOG41082I2 s4 domain protein MY9_0059 ENOG4105VYY sporulation protein yabp MY9_0061 ENOG41060GV RNA binding s1 domain protein MY9_0065 ENOG4108UGV hypoxanthine phosphoribosyltransferase MY9_0066 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) MY9_0068 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) MY9_0069 ENOG4107U48 ppic-type peptidyL-prolyl cis-trans isomerase MY9_0070 ENOG4105C6T cysteine synthase MY9_0071 ENOG4105CRQ synthase (Component I) MY9_0072 ENOG4105DDQ anthranilate synthase MY9_0073 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 MY9_0074 ENOG4105EEI dihydropteroate synthase MY9_0075 ENOG4105KRF dihydroneopterin aldolase MY9_0076 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase MY9_0078 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) MY9_0079 ENOG4105CRK lysyL-tRNA synthetase MY9_0083 ENOG4108Z0C Uvrb UvrC protein MY9_0084 ENOG41066A3 ATP guanido phosphotransferase MY9_0086 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) MY9_0087 ENOG4105E59 Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity) MY9_0088 ENOG4105CTP PilT protein domain protein MY9_0089 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) MY9_0090 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) MY9_0091 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) MY9_0094 ENOG4105D7W serine acetyltransferase MY9_0095 ENOG4105C8N cysteinyl-tRNA synthetase MY9_0096 ENOG4105KEB Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) MY9_0097 ENOG4105C2N RNA methyltransferase TrmH family group 3 MY9_0098 ENOG4105M0M Tetracycline resistance protein MY9_0101 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) MY9_0102 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) MY9_0104 ENOG4108VZM 50s ribosomal protein L10 MY9_0105 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) MY9_0106 ENOG4107Y49 methyltransferase MY9_0107 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) MY9_0108 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) MY9_0109 ENOG4105XPM ribosomal protein MY9_0110 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) MY9_0111 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) MY9_0112 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) MY9_0113 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) MY9_0114 ENOG4107SKW Inherit from COG: Alpha beta hydrolase MY9_0115 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) MY9_0116 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) MY9_0117 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) MY9_0118 ENOG41080UE One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) MY9_0119 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity MY9_0120 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) MY9_0121 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) MY9_0122 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) MY9_0123 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) MY9_0124 ENOG41082SA 50s ribosomal protein l29 MY9_0125 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal MY9_0126 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) MY9_0128 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits MY9_0130 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) MY9_0131 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) MY9_0132 ENOG4105K4C This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity) MY9_0133 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) MY9_0134 ENOG4105VPB 50S ribosomal protein L30 MY9_0135 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) MY9_0136 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) MY9_0138 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) MY9_0140 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) MY9_0142 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits MY9_0143 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) MY9_0144 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) MY9_0145 ENOG4108ZT0 50S ribosomal protein l17 MY9_0146 ENOG4108JJB ABC transporter MY9_0147 ENOG4108JJB ABC transporter MY9_0148 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) MY9_0149 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) MY9_0150 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) MY9_0151 ENOG4108UJD 30S ribosomal protein S9 MY9_0152 ENOG4108I0C methyltransferase MY9_0155 ENOG4105D1F ATP-binding protein MY9_0158 ENOG4108NMV polysaccharide deacetylase MY9_0160 ENOG4108JPW Aminotransferase MY9_0162 ENOG4105CPQ Dehydrogenase MY9_0163 ENOG4105CHH sulfate transporter MY9_0165 ENOG4108SA1 esterase MY9_0169 ENOG410874W AraC family transcriptional regulator MY9_0170 ENOG4105EHZ conserved protein UCP016719 MY9_0171 ENOG4105D17 glycoside hydrolase, family 3 domain protein MY9_0176 ENOG4105EWC Purine nucleoside phosphorylase MY9_0177 ENOG4105EMN RNA polymerase sigma factor MY9_0179 ENOG4105C8B TIGR00159 family MY9_0180 ENOG4107U5W ybbr family MY9_0181 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) MY9_0183 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) MY9_0184 ENOG4105D03 DNA-3-methyladenine glycosylase II MY9_0187 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) MY9_0188 ENOG4108TWJ NADH dehydrogenase subunit 5 MY9_0192 ENOG4105GPN Uncharacterized conserved protein (DUF2294) MY9_0193 ENOG4105WAB arsR family transcriptional regulator MY9_0195 ENOG4108RWP Major Facilitator Superfamily protein MY9_0202 ENOG4105G0J serine threonine protein kinase MY9_0204 ENOG4106K80 MY9_0206 ENOG4106DDH Sporulation-specific SASP protein MY9_0208 ENOG4108HWY Beta-lactamase MY9_0209 ENOG4107E6A Cytochrome p-450 MY9_0212 ENOG4107QTZ amino acid MY9_0214 ENOG4107VXM glycerophosphoryl diester phosphodiesterase MY9_0215 ENOG4105CXY transporter MY9_0217 ENOG410645S MarR family Transcriptional regulator MY9_0218 ENOG4105DCM major facilitator superfamily MY9_0220 ENOG410631K Membrane MY9_0222 ENOG4106AXJ AraC family transcriptional regulator MY9_0224 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR MY9_0225 ENOG4108TCS Glutamyl endopeptidase MY9_0227 ENOG4108WC5 Alpha Beta Hydrolase Fold protein MY9_0228 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase MY9_0229 ENOG4107ZTW SNARE associated Golgi MY9_0233 ENOG4105C72 UPF0176 protein MY9_0235 ENOG4108IIZ The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane MY9_0236 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) MY9_0237 ENOG4108X79 transcriptional regulator MY9_0240 ENOG4105CM2 brancheD-chain amino acid aminotransferase MY9_0241 ENOG4108IQI permease MY9_0242 ENOG4108J5H Homocysteine s-methyltransferase MY9_0244 ENOG4105CSV Glutaminase MY9_0248 ENOG4105C26 Dehydrogenase MY9_0249 ENOG4105DJB Major Facilitator Superfamily MY9_0250 ENOG4105EQX glucarate dehydratase MY9_0251 ENOG41073TP transcriptional regulator MY9_0252 ENOG4105CTX dehydratase MY9_0256 ENOG4106UX7 integral membrane protein MY9_0257 ENOG4105DPZ Two component transcriptional regulator (Winged helix family MY9_0267 ENOG4105DGI Alkaline phosphatase MY9_0268 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) MY9_0269 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) MY9_0270 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) MY9_0271 ENOG4107EPV Aminotransferase class V MY9_0272 ENOG4105C0R drug resistance transporter emrb qaca subfamily MY9_0273 ENOG4105J7D transcriptional regulator MY9_0274 ENOG4107RB3 L-asparaginase MY9_0275 ENOG4108KTS Acetyltransferase and hydrolase with the alpha beta hydrolase fold MY9_0277 ENOG41060AI SEC-C motif MY9_0279 ENOG4107Y7X LytTR MY9_0280 ENOG4108IUW ABC transporter MY9_0281 ENOG4108SDH ABC, transporter MY9_0282 ENOG4107SET aldo keto reductase MY9_0289 ENOG4105H9W Short-chain dehydrogenase reductase Sdr MY9_0291 ENOG4105DSE periplasmic solute binding protein MY9_0292 ENOG4105DIK (ABC) transporter MY9_0294 ENOG4105DEN Luciferase family MY9_0295 ENOG4108N0M stress protein MY9_0296 ENOG4106FN3 tellurium resistance protein MY9_0297 ENOG4106FN3 tellurium resistance protein MY9_0298 ENOG4107TS3 membrane protein, TerC MY9_0299 ENOG4108TTB tellurium resistance protein MY9_0301 ENOG41079KZ Major Facilitator Superfamily MY9_0302 ENOG4107XZQ multidrug resistance protein MY9_0303 ENOG4108A65 Transcriptional regulator MY9_0305 ENOG4108IJ7 Glycine betaine MY9_0306 ENOG4107SQ8 Glycine betaine MY9_0313 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) MY9_0320 ENOG4105EIG urea carboxylase-associated protein 1 MY9_0321 ENOG4107RA1 nh(3)-dependent nad( ) synthetase MY9_0322 ENOG4105I1F Resistance protein MY9_0323 ENOG4107Z3Y Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) MY9_0325 ENOG41089UC methyltransferase, type 11 MY9_0326 ENOG4105C5Q Transcriptional regulator MY9_0327 ENOG4105I82 acetyl xylan esterase MY9_0328 ENOG410756H nucleotidyltransferase MY9_0330 ENOG4105C26 Dehydrogenase MY9_0331 ENOG4105CK7 Sodium proline symporter MY9_0332 ENOG4107YHD transcriptional regulator MY9_0334 ENOG4108PJD permease MY9_0335 ENOG4105U6C Alpha beta hydrolase fold protein MY9_0338 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) MY9_0339 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit MY9_0340 ENOG4108IFG nitrite reductase, (NAD(P)H) MY9_0341 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) MY9_0345 ENOG4105S7A ErfK ybiS ycfS ynhG family protein MY9_0348 ENOG4105CKI cobalamin synthesis protein MY9_0349 ENOG4105E5Q amino acid AbC transporter MY9_0350 ENOG4107XKZ Amino acid ABC superfamily ATP binding cassette transporter binding protein MY9_0351 ENOG4105HHM rdd domain containing protein MY9_0355 ENOG4108VEN abc transporter atp-binding protein MY9_0356 ENOG4105CS2 ec 3.2.1.21 MY9_0359 ENOG4105C8Q Methyl-accepting chemotaxis MY9_0360 ENOG41080HJ 6-phospho 3-hexuloisomerase MY9_0361 ENOG4108VA3 3-hexulose-6-phosphate synthase MY9_0362 ENOG4105KVH Transcriptional regulator MY9_0365 ENOG4105CEY Amp-dependent synthetase and ligase MY9_0372 ENOG4105SX7 Transporter MY9_0373 ENOG4105W8Z 4'-phosphopantetheinyl transferase MY9_0375 ENOG4105CDA abc transporter atp-binding protein MY9_0376 ENOG4105DRP amino acid AbC transporter MY9_0378 ENOG4106P55 Transcriptional regulator MY9_0379 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) MY9_0380 ENOG41069ZX MY9_0381 ENOG41069ZX MY9_0383 ENOG4105DUX Transporter MY9_0386 ENOG4105E1K spore germination protein MY9_0390 ENOG4107WD8 ABC transporter, permease MY9_0391 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MY9_0392 ENOG4105BZU Histidine kinase MY9_0395 ENOG4105CFH Aspartokinase MY9_0396 ENOG4105DHS permease protein MY9_0397 ENOG4105CM4 permease protein MY9_0398 ENOG4108IPW abc transporter atp-binding protein MY9_0401 ENOG4105R8C Transcriptional regulator MY9_0402 ENOG4108DBC nitroreductase MY9_0403 ENOG41067V3 Antibiotic biosynthesis monooxygenase MY9_0404 ENOG4105YVS arsR family transcriptional regulator MY9_0406 ENOG4108JPW Aminotransferase MY9_0407 ENOG4105C26 Dehydrogenase MY9_0409 ENOG4105H9W Short-chain dehydrogenase reductase Sdr MY9_0410 ENOG4105KTB nuclear export factor GLE1 MY9_0411 ENOG4108T5E Copper resistance protein MY9_0412 ENOG4108ZYE Transcriptional regulator MY9_0417 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) MY9_0418 ENOG4108ZX0 Signal peptidase I MY9_0423 ENOG4105E7W lamb ycsf family protein MY9_0424 ENOG4105C5A transporter MY9_0425 ENOG4105CFM UPF0317 protein MY9_0426 ENOG4105P4J Allophanate hydrolase, subunit 1 MY9_0428 ENOG4107258 Transcriptional regulator MY9_0429 ENOG4105XJB lipolytic protein G-D-S-L family MY9_0432 ENOG41061CK Antibiotic biosynthesis monooxygenase MY9_0433 ENOG4107RVG penicillin-binding protein MY9_0434 ENOG4107QM2 Aldo Keto reductase MY9_0435 ENOG4105ETD TRANSCRIPTIONal MY9_0437 ENOG4105HMZ Methyltransferase MY9_0438 ENOG4105CYX Short-chain dehydrogenase reductase Sdr MY9_0441 ENOG410606W general stress protein MY9_0443 ENOG4105VCH membrane MY9_0445 ENOG4105C9U ATP-dependent DNA helicase RecQ MY9_0448 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) MY9_0449 ENOG4107R8N Glycosyl transferase, family 2 MY9_0452 ENOG4105C0X amino acid MY9_0457 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) MY9_0459 ENOG4105NRR Uncharacterized protein conserved in bacteria (DUF2188) MY9_0460 ENOG4105EU9 MY9_0461 ENOG4105QVS general stress protein MY9_0462 ENOG41082W1 Cupin 2, conserved barrel domain protein MY9_0465 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit MY9_0466 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism MY9_0467 ENOG4108MRH transcriptional regulatory protein MY9_0468 ENOG4107QJT sodium dicarboxylate symporter MY9_0469 ENOG4106F5Q Membrane MY9_0471 ENOG4105CJ1 ABC, transporter MY9_0474 ENOG4105FDT acyl-CoA dehydrogenase MY9_0478 ENOG4105SZ6 Thioredoxin MY9_0479 ENOG4105CPF Cell wall formation (By similarity) MY9_0480 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) MY9_0481 ENOG4105C1J atp-dependent rna helicase MY9_0482 ENOG410905X membrane-flanked domain protein MY9_0483 ENOG4105CKV Membrane MY9_0485 ENOG41082V8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) MY9_0486 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein MY9_0487 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) MY9_0489 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) MY9_0490 ENOG4107MMM Anti-sigma-factor antagonist MY9_0491 ENOG4105FUA antagonist MY9_0492 ENOG4105QD0 anti-sigma regulatory factor serine threonine protein kinase MY9_0493 ENOG4107SGM protein serine threonine phosphatase MY9_0494 ENOG4105WN5 stage II sporulation protein MY9_0495 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) MY9_0497 ENOG41064BQ Phosphatase MY9_0499 ENOG4105M5P UPF0310 protein MY9_0500 ENOG4105RV9 Transcriptional regulator MY9_0504 ENOG4105EYG tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity) MY9_0505 ENOG41068WC Domain of unknown function (DUF955) MY9_0506 ENOG4108IMY Transcriptional regulator MY9_0510 ENOG4108RYM conjugative transposon protein MY9_0511 ENOG4106BHR ftsk SpoIIIE family protein MY9_0512 ENOG4106128 DNA-binding helix-turn-helix protein MY9_0517 ENOG41062IR nudix hydrolase MY9_0525 ENOG4105P1M Domain of unknown function (DUF1874) MY9_0527 ENOG4105K4H Nlp p60 protein MY9_0537 ENOG4106ANW SMI1_KNR4 MY9_0538 ENOG4106BHF MY9_0541 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein MY9_0546 ENOG4108V4B ThiJ pfpI MY9_0547 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) MY9_0548 ENOG4105DJ2 Major Facilitator Superfamily MY9_0549 ENOG4107RSM transcriptional regulator MY9_0550 ENOG4108RPX mosc domain containing protein MY9_0551 ENOG4105N14 lysine exporter protein LysE YggA MY9_0555 ENOG4105VEQ Cold shock protein MY9_0558 ENOG4108MCI Transcriptional regulator, ARAC family MY9_0559 ENOG4108UZ3 Transporter MY9_0560 ENOG41086D8 Transcriptional regulator MY9_0561 ENOG4107U9B transcriptional regulator MY9_0562 ENOG4105DXI Major Facilitator superfamily MY9_0564 ENOG4105CZ9 Domain of unknown function (DU1801) MY9_0565 ENOG4105GIG MY9_0566 ENOG4105T38 integral membrane protein MY9_0567 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family MY9_0568 ENOG4108ZMQ domain protein MY9_0569 ENOG4105MJ9 esterase MY9_0570 ENOG4107Z6X Transcriptional regulator MY9_0572 ENOG4105EQ0 Major Facilitator superfamily MY9_0573 ENOG4108JGH Tetr family transcriptional regulator MY9_0576 ENOG41082YX Transcriptional regulator, arsr family MY9_0577 ENOG4107R5R arsenical pump membrane protein MY9_0578 ENOG4108UXE Protein tyrosine phosphatase MY9_0579 ENOG4105Z7P Acetyltransferase (GNAT) family MY9_0580 ENOG4108KGH TRANSCRIPTIONal MY9_0581 ENOG4108ZJ4 polysaccharide deacetylase MY9_0583 ENOG4105US7 Histidine kinase MY9_0584 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MY9_0585 ENOG4107Y9U Membrane MY9_0587 ENOG4108SQ9 flavin reductase domain protein, FMN-binding MY9_0588 ENOG4108ZHR arsR family transcriptional regulator MY9_0589 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) MY9_0593 ENOG4105ENE Histidine kinase MY9_0594 ENOG4108VB1 regulatoR MY9_0595 ENOG4105EYF MMPL domain protein MY9_0598 ENOG4108WC5 Alpha Beta Hydrolase Fold protein MY9_0599 ENOG4107U9B transcriptional regulator MY9_0600 ENOG4108UMN azlc family MY9_0601 ENOG4105KMT branched-chain amino acid MY9_0605 ENOG4108UQV Membrane MY9_0606 ENOG4108Z5V transcriptional regulator, merr family MY9_0607 ENOG41076HS cation diffusion facilitator family transporter MY9_0608 ENOG4108TVJ Nitroreductase MY9_0609 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase MY9_0610 ENOG4108VGI doxx family MY9_0611 ENOG4105XXY Thioredoxin MY9_0615 ENOG410900G Protein of unknown function (DUF421) MY9_0616 ENOG4108QY0 Membrane MY9_0620 ENOG4105PF9 Transcriptional regulator MY9_0622 ENOG4105WQG acetyltransferase MY9_0624 ENOG4105C85 amino acid MY9_0626 ENOG41062A4 Transcriptional regulator MY9_0627 ENOG4105EYF MMPL domain protein MY9_0628 ENOG4108TVJ Nitroreductase MY9_0629 ENOG4105FS7 Transcriptional regulator MY9_0630 ENOG4105C2C drug resistance transporter, Bcr CflA MY9_0632 ENOG4105DRR Transcriptional regulator, GntR family MY9_0633 ENOG4105VRS hydrolase family 18 MY9_0636 ENOG4105G6Z alkaline phosphatase MY9_0637 ENOG4108ZMX Domain of unknown function (DU1801) MY9_0639 ENOG4108YM7 Gcn5-related n-acetyltransferase MY9_0640 ENOG4107TVP HD domain protein MY9_0642 ENOG41090UD (LipO)protein MY9_0643 ENOG4105F27 Major Facilitator MY9_0644 ENOG4105VZJ PTS System MY9_0645 ENOG4105VCP PTS System MY9_0646 ENOG4105CK1 PTS System MY9_0647 ENOG4105CS2 ec 3.2.1.21 MY9_0648 ENOG4108TZY GntR Family Transcriptional Regulator MY9_0649 ENOG4105EVU fructokinase MY9_0650 ENOG4105DG6 mannose-6-phosphate isomerase MY9_0651 ENOG4105D3P Mannan endo-1,4-beta-mannosidase MY9_0653 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) MY9_0654 ENOG4105K8N protein family UPF0079, ATPase MY9_0655 ENOG41072GX Peptidase M22 Glycoprotease MY9_0656 ENOG410801F ribosomal-protein-alanine acetyltransferase MY9_0657 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) MY9_0659 ENOG4105C5H ABC transporter MY9_0660 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) MY9_0661 ENOG4105FF6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity) MY9_0662 ENOG41067S4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) MY9_0663 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) MY9_0665 ENOG4108TYN CAAX amino terminal protease family protein MY9_0666 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) MY9_0667 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) MY9_0670 ENOG4105E7U AraC family transcriptional regulator MY9_0672 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase MY9_0673 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) MY9_0675 ENOG4105EUJ GTP cyclohydrolase i MY9_0676 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) MY9_0680 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) MY9_0681 ENOG4107RCH Diaminopropionate ammonia-lyase MY9_0683 ENOG4105BZ1 (ABC) transporter MY9_0684 ENOG4105PGZ NB-ARC domain MY9_0685 ENOG4105CPQ Dehydrogenase MY9_0686 ENOG4105CT4 transporter MY9_0688 ENOG41087YS Phage shock protein A MY9_0689 ENOG4105DQX Zinc finger domain MY9_0690 ENOG4108WV1 Pfam:DUF477 MY9_0692 ENOG4108ZMR Ion transport 2 domain-containing protein MY9_0694 ENOG4107QNK )-transporter MY9_0700 ENOG4107YUH hydrolase MY9_0702 ENOG4107STQ Multicopper oxidase MY9_0703 ENOG4105C85 amino acid MY9_0705 ENOG4105C7R Atpase associated with various cellular activities aaa_3 MY9_0712 ENOG4105C7N Xanthine uracil vitamin C permease MY9_0717 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) MY9_0718 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit MY9_0719 ENOG4105C83 adenylosuccinate lyase MY9_0720 ENOG4105C8V SAICAR synthetase MY9_0721 ENOG4105VR9 phosphoribosylformylglycinamidine synthase MY9_0722 ENOG4105D21 Phosphoribosylformylglycinamidine synthase I MY9_0723 ENOG4108JIU phosphoribosylformylglycinamidine synthase ii MY9_0725 ENOG4105CXB phosphoribosylaminoimidazole synthetase MY9_0726 ENOG4108V3E phosphoribosylglycinamide formyltransferase MY9_0727 ENOG4105DC1 bifunctional purine biosynthesis protein purh MY9_0728 ENOG4105C12 Phosphoribosylglycinamide synthetase MY9_0730 ENOG4105DVH amino acid MY9_0732 ENOG4108R5T secreted protein MY9_0733 ENOG4105KGF protein, YerC YecD MY9_0734 ENOG4105CBC glutamate synthase MY9_0736 ENOG4108RTE 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity) MY9_0737 ENOG4105C4R Atp-dependent dna helicase MY9_0738 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) MY9_0742 ENOG4108A04 Beta-lactamase MY9_0745 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase MY9_0754 ENOG4105CRN Aminoglycoside phosphotransferase MY9_0755 ENOG4105G6Z alkaline phosphatase MY9_0756 ENOG4105KT7 mgtC SapB transporter MY9_0757 ENOG4105CK7 Sodium proline symporter MY9_0758 ENOG4105VB5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) MY9_0759 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) MY9_0760 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) MY9_0761 ENOG4108IG5 Transcriptional regulator MY9_0763 ENOG4105CBD Diacylglycerol kinase MY9_0764 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) MY9_0772 ENOG4108QY0 Membrane MY9_0776 ENOG4105CDY transcriptional regulatory protein MY9_0778 ENOG4105M4P Tetr family transcriptional regulator MY9_0779 ENOG41062KD Inherit from COG: ketosteroid isomerase-like protein MY9_0780 ENOG4107S9F NmrA family MY9_0783 ENOG4105WEF catalase MY9_0784 ENOG4105M18 -acetyltransferase MY9_0787 ENOG4105C2F Histidine kinase MY9_0788 ENOG4105EQD regulatoR MY9_0789 ENOG410769Z extracellular solute-binding protein family 1 MY9_0790 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component MY9_0791 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component MY9_0792 ENOG4105F5H Glycosyl Hydrolase Family 88 MY9_0793 ENOG41075H3 AraC family transcriptional regulator MY9_0794 ENOG4107TDE lipolytic protein G-D-S-L family MY9_0797 ENOG4105CX8 fg-gap repeat protein MY9_0798 ENOG4105CX8 fg-gap repeat protein MY9_0799 ENOG4107TDE lipolytic protein G-D-S-L family MY9_0801 ENOG4105EKC MY9_0802 ENOG4105E0S extracellular solute-binding protein family 1 MY9_0804 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component MY9_0805 ENOG4105F8D glycoside hydrolase family 4 MY9_0806 ENOG4105H67 Protein of unknown function (DUF421) MY9_0807 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) MY9_0808 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MY9_0813 ENOG4106I4J membrane MY9_0814 ENOG41061H0 Monooxygenase MY9_0815 ENOG4108R1P MY9_0816 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) MY9_0818 ENOG4105E0M Sulfatase MY9_0820 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase MY9_0822 ENOG41090R9 glycosyltransferase MY9_0823 ENOG4107R51 Glycosyl transferase, family 2 MY9_0824 ENOG41090R9 glycosyltransferase MY9_0825 ENOG4105EU0 Major facilitator Superfamily MY9_0828 ENOG4105CUB amino acid MY9_0829 ENOG4105C26 Dehydrogenase MY9_0830 ENOG4105FKZ Methyl-accepting chemotaxis MY9_0831 ENOG4105C5H ABC transporter MY9_0833 ENOG4107SWG transcriptional regulator MERR family MY9_0834 ENOG4105DXB Major Facilitator superfamily MY9_0836 ENOG4105C5H ABC transporter MY9_0837 ENOG4105FDU atp-dependent rna helicase MY9_0839 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein MY9_0840 ENOG4105E0A ABC, transporter MY9_0841 ENOG4108U1V ABC transporter, permease MY9_0842 ENOG4105DQ5 transport system permease protein MY9_0843 ENOG4108HUF Transporter MY9_0846 ENOG4108J20 pectate lyase MY9_0847 ENOG4107QPK )-transporter MY9_0849 ENOG4108MRH transcriptional regulatory protein MY9_0855 ENOG410855V Acylphosphatase MY9_0856 ENOG4108RPX mosc domain containing protein MY9_0860 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) MY9_0866 ENOG4105GEU Spore germination protein MY9_0867 ENOG4105C5Y PTS System MY9_0868 ENOG4105CG3 alpha amylase, catalytic region MY9_0869 ENOG4107414 GntR family transcriptional regulator MY9_0870 ENOG4108RCM Nitroreductase MY9_0871 ENOG4105CGH 5'-nucleotidase MY9_0872 ENOG4107RKG DJ-1/PfpI family MY9_0877 ENOG4105KJF protein tyrosine phosphatase MY9_0879 ENOG4107U9T Pfam:Ribonuclease_BN MY9_0880 ENOG4108ISG Major Facilitator MY9_0882 ENOG4105UPD Calcium Proton MY9_0884 ENOG4105D8X mechanosensitive ion channel MY9_0888 ENOG4106KE4 Dehydrogenase MY9_0889 ENOG4105D7N magnesium and cobalt transport protein CorA MY9_0897 ENOG4107RUY (E1 component), alpha subunit MY9_0899 ENOG4107QKR Dehydrogenase MY9_0901 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family MY9_0902 ENOG41069DP small acid-soluble spore protein MY9_0903 ENOG4105KK4 UPF0060 membrane protein MY9_0908 ENOG4105F8D glycoside hydrolase family 4 MY9_0909 ENOG4108Q3X Transcriptional regulator MY9_0910 ENOG4105CI1 PTS System MY9_0912 ENOG4105BZ1 (ABC) transporter MY9_0913 ENOG4105BZ1 (ABC) transporter MY9_0915 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase MY9_0916 ENOG4105BZU Histidine kinase MY9_0917 ENOG4105WH1 Two component transcriptional regulator luxr family MY9_0918 ENOG4105CJ1 ABC, transporter MY9_0919 ENOG41090VJ ABC-2 type transporter MY9_0920 ENOG4108KYE ABC-2 type transporter MY9_0921 ENOG4105U3E Transcriptional regulator MY9_0924 ENOG4105H93 Acyltransferase family MY9_0925 ENOG4105YA8 Transcriptional regulator MY9_0926 ENOG4107Y80 Major Facilitator superfamily MY9_0927 ENOG4108YYS metal-dependent hydrolase (By similarity) MY9_0929 ENOG4105C0R drug resistance transporter emrb qaca subfamily MY9_0930 ENOG410834F Transcriptional regulator MY9_0932 ENOG4108MES Periplasmic binding protein MY9_0933 ENOG4105DQ5 transport system permease protein MY9_0934 ENOG4108IHU transport system permease protein MY9_0935 ENOG4105JAB phenazine biosynthesis protein, phzf family MY9_0936 ENOG4107Y03 Nitroreductase MY9_0939 ENOG4105ECP epimerase MY9_0942 ENOG4105F27 Major Facilitator MY9_0947 ENOG4106AKJ MY9_0948 ENOG4105D74 hydrolase MY9_0949 ENOG4105CKK Glycosyl transferase, family 2 MY9_0950 ENOG4105EJV Membrane MY9_0951 ENOG41067AE Membrane-bound metal-dependent hydrolase MY9_0952 ENOG4105CEN a g-specific adenine glycosylase MY9_0953 ENOG4106BXE MY9_0954 ENOG4105CAN Short-chain dehydrogenase reductase Sdr MY9_0957 ENOG4105EVI UPF0374 protein MY9_0958 ENOG4105BZ1 (ABC) transporter MY9_0959 ENOG4107NBY Membrane MY9_0961 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MY9_0962 ENOG4105G5W regulator Fur family MY9_0965 ENOG4108N23 SpoOM-related protein MY9_0968 ENOG4105EC3 peptidase S51, dipeptidase E MY9_0970 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) MY9_0971 ENOG4105DNP FAD linked oxidase domain protein MY9_0974 ENOG4105E2Y ABC, transporter MY9_0975 ENOG4108J8Z aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein MY9_0976 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component MY9_0977 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) MY9_0980 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) MY9_0981 ENOG4107D63 MY9_0982 ENOG4105VZ8 Transcriptional regulator MY9_0984 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) MY9_0986 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) MY9_0990 ENOG4105CYN Serine protein kinase MY9_0991 ENOG4106AKX UPF0229 protein MY9_0992 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes MY9_0993 ENOG4105CW7 secretion protein, HlyD family MY9_0994 ENOG4105C0R drug resistance transporter emrb qaca subfamily MY9_0995 ENOG4105CS1 NAD(P)H quinone oxidoreductase MY9_0998 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family MY9_0999 ENOG4105CZV ABC transporter MY9_1000 ENOG4105CJ1 ABC, transporter MY9_1001 ENOG4108TU7 Inherit from COG: (ABC) transporter MY9_1003 ENOG4105VEQ Cold shock protein MY9_1005 ENOG4105BZU Histidine kinase MY9_1016 ENOG4108YBP pseudouridine synthase MY9_1018 ENOG41080XP Cbs domain MY9_1019 ENOG4107YBY Hydrolase MY9_1020 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase MY9_1022 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) MY9_1023 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator MY9_1025 ENOG4108HMR Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) MY9_1026 ENOG4105C6V Glycerol-3-phosphate dehydrogenase MY9_1028 ENOG4105BZU Histidine kinase MY9_1029 ENOG4105WH1 Two component transcriptional regulator luxr family MY9_1036 ENOG4105ED1 spovr family MY9_1037 ENOG4105G6Z alkaline phosphatase MY9_1040 ENOG4105BZN citrate synthase MY9_1041 ENOG4105CYX Short-chain dehydrogenase reductase Sdr MY9_1042 ENOG4105CUB amino acid MY9_1043 ENOG4105C8J )-transporter MY9_1044 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family MY9_1047 ENOG4105J37 MY9_1048 ENOG4108AEY RNA polymerase sigma factor MY9_1049 ENOG4108FN7 Aldo keto reductase MY9_1050 ENOG4105F6E Acyl-transferase MY9_1051 ENOG4105C37 (CBS) domain MY9_1053 ENOG4105CHM Aminotransferase MY9_1054 ENOG4105C37 (CBS) domain MY9_1056 ENOG4105WMR Protein CrcB homolog MY9_1057 ENOG4108QXE glycerophosphoryl diester phosphodiesterase MY9_1059 ENOG4105D64 Mechanosensitive ion channel MY9_1060 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) MY9_1061 ENOG4107VMI polysaccharide deacetylase MY9_1062 ENOG4105F0I Aminotransferase MY9_1066 ENOG4105BZ1 (ABC) transporter MY9_1067 ENOG4105BZ1 (ABC) transporter MY9_1072 ENOG410839P MY9_1074 ENOG4106MP8 UPF0754 membrane protein MY9_1075 ENOG4105WZB UPF0342 protein MY9_1076 ENOG4105F1N DNA alkylation repair MY9_1079 ENOG4105D4P Coproporphyrinogen iii oxidase MY9_1080 ENOG4107S91 Sodium hydrogen exchanger MY9_1081 ENOG4105NCW Trka-c domain protein MY9_1083 ENOG4105CGU Enoyl-CoA hydratase MY9_1085 ENOG4108IUX (ABC) transporter MY9_1086 ENOG4105RHA ABC transporter, permease MY9_1087 ENOG4107VRP DNA repair exonuclease MY9_1088 ENOG4106D4I domain protein MY9_1089 ENOG4105EQI Metal Dependent Phosphohydrolase MY9_1091 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) MY9_1099 ENOG4105NBU tryptophan transport protein MY9_1100 ENOG4105DXJ Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) MY9_1101 ENOG4105K59 histidine triad (HIT) protein MY9_1110 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation MY9_1111 ENOG4105BZ4 penicillin-binding protein MY9_1112 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) MY9_1114 ENOG4107TTW Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) MY9_1115 ENOG4105C1Q protoporphyrinogen oxidase MY9_1117 ENOG4105ECB domain protein MY9_1119 ENOG41090T1 Membrane MY9_1121 ENOG4105DER m42 family MY9_1124 ENOG4106AXD MY9_1125 ENOG4108RQ5 Beta-lactamase domain-containing protein MY9_1126 ENOG4105DF9 Lipoate-protein, ligase MY9_1128 ENOG4105CEY Amp-dependent synthetase and ligase MY9_1130 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 MY9_1132 ENOG4105KD7 acetyltransferase MY9_1135 ENOG4108HUF Transporter MY9_1136 ENOG4107TB6 phosphoglycerate mutase MY9_1138 ENOG4107F3J Amp-dependent synthetase and ligase MY9_1139 ENOG4107ZYJ bioY protein MY9_1140 ENOG4106YBV Methyl-accepting chemotaxis MY9_1144 ENOG4105XVF Competence transcription factor MY9_1145 ENOG4105CYX Short-chain dehydrogenase reductase Sdr MY9_1146 ENOG4105X3H Excalibur domain protein MY9_1147 ENOG4105E1V na solute symporter MY9_1148 ENOG4106CAD Protein of unknown function (DUF3311) MY9_1149 ENOG41060YP MY9_1152 ENOG4107SCK Monooxygenase MY9_1153 ENOG4108INS Transcriptional regulator MY9_1155 ENOG4108KK1 membrane protein AbrB duplication MY9_1156 ENOG4106K7D Major facilitator family transporter MY9_1157 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) MY9_1158 ENOG4105VWP Inherit from COG: 4Fe-4S ferredoxin, iron-sulfur binding MY9_1161 ENOG4107R2I The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation MY9_1163 ENOG4105EYH Exonuclease MY9_1174 ENOG4105ERH Fumarylacetoacetate hydrolase MY9_1176 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin MY9_1178 ENOG4105CAQ asparagine synthetase MY9_1180 ENOG4105UQX Mate efflux family protein MY9_1181 ENOG4106HBX Transcriptional Regulator AraC Family MY9_1182 ENOG4105ETE Transcriptional regulator (LacI family MY9_1184 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) MY9_1185 ENOG4105SF0 DinB family MY9_1186 ENOG4108ZUB Lysine exporter protein (Lyse ygga) MY9_1187 ENOG4105MYW Pentapeptide repeat protein MY9_1188 ENOG4107S9D Alpha beta hydrolase MY9_1189 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) MY9_1190 ENOG4107RIQ Sulfate adenylate transferase MY9_1191 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) MY9_1192 ENOG4108N5B 2-phosphosulfolactate phosphatase MY9_1193 ENOG41061P3 phosphosulfolactate synthase MY9_1195 ENOG4105DIA mandelate racemase muconate lactonizing MY9_1196 ENOG4107RCC Major Facilitator Superfamily MY9_1197 ENOG4108SZE gCN5-related N-acetyltransferase MY9_1198 ENOG4105MA6 gCN5-related N-acetyltransferase MY9_1200 ENOG4108VPT UPF0234 protein MY9_1201 ENOG4105QNR S1 RNA binding domain protein MY9_1205 ENOG4105K7K Transcriptional regulator MY9_1207 ENOG410751J MY9_1208 ENOG4105D4Y metalloprotease MY9_1209 ENOG4105EPR degv family MY9_1210 ENOG4107AYK membrAne MY9_1212 ENOG41073B9 MY9_1214 ENOG4108KP7 hydrolase MY9_1215 ENOG4108MXZ Esterase MY9_1216 ENOG4105VG1 fes assembly suf system protein MY9_1218 ENOG4105IQ5 FAD linked oxidase domain protein MY9_1220 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase MY9_1223 ENOG4105C8Y Acetylornithine aminotransferase MY9_1224 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain MY9_1226 ENOG4105DBV ornithine carbamoyltransferase MY9_1231 ENOG4107RMD Basic membrane lipoprotein MY9_1234 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) MY9_1235 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) MY9_1237 ENOG4105C3U ABC transporter MY9_1238 ENOG4108JQ7 (ABC) transporter MY9_1241 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component MY9_1243 ENOG4105C31 Tryptophanyl-tRNA synthetase MY9_1245 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component MY9_1246 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component MY9_1248 ENOG4108JQ7 (ABC) transporter MY9_1252 ENOG41090SU Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity) MY9_1253 ENOG4108ZCF integral membrane protein MY9_1254 ENOG4108SQ7 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis MY9_1257 ENOG4105DPN Oligoendopeptidase f MY9_1260 ENOG4105T58 Dithiol-disulfide isomerase MY9_1261 ENOG4108Z18 K06886 hemoglobin MY9_1262 ENOG4105E4C Lytic transglycosylase catalytic MY9_1263 ENOG4105MIX Adenylate cyclase MY9_1266 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) MY9_1267 ENOG4105EMS pseudouridine synthase MY9_1270 ENOG4105ETU transcriptional activator (TenA MY9_1271 ENOG4108VEU Thiamine monophosphate synthase MY9_1274 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) MY9_1275 ENOG4105D06 uba thif-type nad fad binding protein MY9_1276 ENOG4105DWF phosphomethylpyrimidine kinase MY9_1277 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH MY9_1278 ENOG4107A88 MY9_1289 ENOG4105ENA helicase MY9_1292 ENOG4108ZMI UPF0477 protein MY9_1295 ENOG4105C28 cystathionine MY9_1296 ENOG4105C28 cystathionine MY9_1297 ENOG4105D9U N-acetyltransferase MY9_1298 ENOG4105JHY Membrane MY9_1302 ENOG4106BHF MY9_1311 ENOG4105DM4 PTS System MY9_1312 ENOG4105DG6 mannose-6-phosphate isomerase MY9_1313 ENOG4105G7B Protein of unknown function (DUF2992) MY9_1314 ENOG4105VMI -acetyltransferase MY9_1316 ENOG4108Z66 YbaK ebsC protein MY9_1320 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) MY9_1322 ENOG4108ZJ4 polysaccharide deacetylase MY9_1323 ENOG4107CUJ Protein of unknown function (DUF2690) MY9_1328 ENOG4108IEG Formate dehydrogenase Alpha subunit MY9_1333 ENOG4106A3M Cytochrome p-450 MY9_1334 ENOG41087PP glycosyltransferase MGT family MY9_1336 ENOG4105EXQ uroporphyrinogen iii synthase hem4 MY9_1337 ENOG4105C4B ABC transporter, permease MY9_1338 ENOG4108IXI (ABC) transporter MY9_1340 ENOG4105Q95 Cupin 2, conserved barrel domain protein MY9_1344 ENOG4105D2H Uronic isomerase MY9_1345 ENOG4105CT4 transporter MY9_1346 ENOG4105DG4 malate L-lactate dehydrogenase MY9_1347 ENOG4105CPQ Dehydrogenase MY9_1348 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) MY9_1349 ENOG4105DMW Dehydrogenase reductase MY9_1350 ENOG4108I5G Major Facilitator superfamily MY9_1351 ENOG4107KJX Transcriptional regulator MY9_1352 ENOG4107QZW Altronate oxidoreductase MY9_1353 ENOG4105CTX dehydratase MY9_1354 ENOG4107TSN permease MY9_1356 ENOG4105JD4 ATPase yjob MY9_1359 ENOG41068K0 YCII-related domain MY9_1360 ENOG4105T4X n-acetylmuramoyl-l-alanine amidase MY9_1361 ENOG4105KWG Pfam:DUF1696 MY9_1362 ENOG4105K7W phage-related replication protein MY9_1363 ENOG4105WEF catalase MY9_1364 ENOG410635T phage-like element pbsx protein MY9_1374 ENOG4108TFU terminase (Small subunit) MY9_1375 ENOG4105IG6 Phage terminase, large subunit MY9_1376 ENOG4108MDF Phage Portal Protein MY9_1381 ENOG41060SN MY9_1384 ENOG4105PQS phage protein MY9_1385 ENOG4105FR7 XkdM protein, phage-like element PBSX MY9_1386 ENOG4105MTC XkdN-like protein MY9_1388 ENOG4108FKH Transglycosylase SLT domain MY9_1388 ENOG4108FKH Transglycosylase SLT domain MY9_1389 ENOG4108WZM domain protein MY9_1390 ENOG4105X7F MY9_1392 ENOG4105MFU Protein of unknown function (DUF2634) MY9_1393 ENOG41066EA baseplate J family protein MY9_1394 ENOG410906S phage-like element pbsx protein xkdt MY9_1396 ENOG41068G1 MY9_1402 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase MY9_1406 ENOG4105CJ3 phosphate transporter MY9_1407 ENOG4107GRR phosphate transport regulator MY9_1408 ENOG4107R7I amino acid MY9_1411 ENOG4105EDW glycosyl transferase, family 39 MY9_1412 ENOG4105CKK Glycosyl transferase, family 2 MY9_1414 ENOG4105C0H protease MY9_1416 ENOG4108ME1 Peptidase M55 D-aminopeptidase MY9_1417 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component MY9_1418 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component MY9_1419 ENOG4105C3U ABC transporter MY9_1422 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A MY9_1423 ENOG4105DTQ mandelate racemase muconate lactonizing MY9_1424 ENOG4107SN7 NLP P60 protein MY9_1425 ENOG4108JQ7 (ABC) transporter MY9_1426 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) MY9_1427 ENOG4107TUM Amidinotransferase MY9_1428 ENOG4108S4H thioesterase Superfamily protein MY9_1429 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) MY9_1433 ENOG4108428 Inherit from COG: -acetyltransferase MY9_1435 ENOG41080TC multidrug resistance protein MY9_1436 ENOG4105CIY formyltetrahydrofolate deformylase MY9_1437 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) MY9_1440 ENOG4105K56 Transcriptional regulator MY9_1441 ENOG4108ZHJ Organic hydroperoxide resistance protein MY9_1443 ENOG4107Y2X deaminase MY9_1445 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) MY9_1448 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin MY9_1450 ENOG4108W7F transporter, permease MY9_1451 ENOG4108JJB ABC transporter MY9_1452 ENOG4105NSK ABC superfamily ATP binding cassette transporter membrane protein MY9_1453 ENOG4108X43 YKOF domain protein MY9_1454 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MY9_1455 ENOG41062D9 Histidine kinase MY9_1458 ENOG4105CJW magnesium transporter MY9_1459 ENOG4105V75 Transcriptional regulator MY9_1468 ENOG4105DQE DNA ligase MY9_1469 ENOG4105FDF Could be involved in DNA repair (By similarity) MY9_1470 ENOG4105BZU Histidine kinase MY9_1471 ENOG4107T5V SNARE associated Golgi MY9_1472 ENOG4107TS3 membrane protein, TerC MY9_1473 ENOG4108WZW RNA polymerase sigma MY9_1475 ENOG410681C small acid-soluble spore protein MY9_1477 ENOG4105D0M Protease HtpX homolog MY9_1481 ENOG4105BZU Histidine kinase MY9_1482 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) MY9_1484 ENOG4105C35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity) MY9_1485 ENOG4105CT5 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity) MY9_1486 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase MY9_1488 ENOG4107T6J Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit MY9_1489 ENOG4105JAS Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene) (By similarity) MY9_1490 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) MY9_1491 ENOG4108CAF Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity) MY9_1495 ENOG4105BZU Histidine kinase MY9_1496 ENOG41090MY MarR family Transcriptional regulator MY9_1497 ENOG4105ER2 Ompa motb domain protein MY9_1498 ENOG4105E14 MotA TolQ exbB proton channel MY9_1500 ENOG4108K88 Membrane MY9_1501 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) MY9_1502 ENOG4107ZAE 6-carboxy-5,6,7,8-tetrahydropterin synthase MY9_1503 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) MY9_1508 ENOG4105VTR Integrase MY9_1509 ENOG4105CSD Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) MY9_1513 ENOG4105F0V Cell wall hydrolase MY9_1516 ENOG4105C59 p-type ATPase MY9_1518 ENOG4105DC7 peptidase M24 MY9_1522 ENOG4105CID antiterminator MY9_1524 ENOG4105KRI phosphocarrier protein (HPr MY9_1525 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) MY9_1527 ENOG4105F6S Spore photoproduct lyase MY9_1529 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer MY9_1531 ENOG4105F9V Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid MY9_1532 ENOG4105K4I Scp-like extracellular MY9_1535 ENOG4105BZU Histidine kinase MY9_1536 ENOG4105CHM Aminotransferase MY9_1538 ENOG4107R88 Chemotaxis protein (CheV) MY9_1539 ENOG4105UIN MY9_1541 ENOG4107Y2H ErfK ybiS ycfS ynhG family protein MY9_1543 ENOG4105K6S Short-chain dehydrogenase reductase Sdr MY9_1544 ENOG4105EPM Diguanylate phosphodiesterase MY9_1546 ENOG4107IN1 Protein of unknown function (DUF1797) MY9_1547 ENOG4108XRC Protein of unknown function (DUF458) MY9_1553 ENOG4105NQC Flavodoxin MY9_1555 ENOG4105CH2 amidohydrolase MY9_1557 ENOG4105D8X mechanosensitive ion channel MY9_1558 ENOG4105D3R alkyl hydroperoxide reductase MY9_1559 ENOG4107R19 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MY9_1562 ENOG41082CS Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) MY9_1563 ENOG4105D06 uba thif-type nad fad binding protein MY9_1564 ENOG4105CVM Molybdenum cofactor synthesis domain protein MY9_1565 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein MY9_1566 ENOG4108ZAF Molybdopterin MY9_1567 ENOG41067WU Molybdopterin converting factor (Subunit 1) MY9_1568 ENOG4105BZ1 (ABC) transporter MY9_1569 ENOG4105BZ1 (ABC) transporter MY9_1571 ENOG4107X8C Efflux transporter RND family MFP subunit MY9_1572 ENOG4105C19 ABC transporter MY9_1573 ENOG4107RBB ABC transporter, permease MY9_1574 ENOG4105E98 transcriptional regulator DeoR family MY9_1575 ENOG4105DE4 1-phosphofructokinase MY9_1576 ENOG4105DM4 PTS System MY9_1577 ENOG4105C3F Signal peptidase i MY9_1579 ENOG4105C5H ABC transporter MY9_1580 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) MY9_1586 ENOG4105BZU Histidine kinase MY9_1588 ENOG4107ZYR domain protein MY9_1590 ENOG4105CN5 Metallo-Beta-Lactamase MY9_1593 ENOG4108X4Q Hydrolase MY9_1594 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) MY9_1598 ENOG4105CPP Dehydrogenase, E1 component MY9_1599 ENOG4105C7S Dehydrogenase MY9_1600 ENOG4107QN2 dihydrolipoyl dehydrogenase MY9_1603 ENOG4105CXN decarboxylase MY9_1604 ENOG4105WBI UPF0223 protein MY9_1607 ENOG4105ECY inositol monophosphatase MY9_1609 ENOG4105JQZ Methyltransferase MY9_1617 ENOG4105CI3 gtp-binding protein typa MY9_1618 ENOG4105QA2 MY9_1621 ENOG4108IAB Phoh family MY9_1623 ENOG4105CSV Glutaminase MY9_1624 ENOG4105ZPI UPF0358 protein MY9_1625 ENOG4105CNI cell division protein FtsW MY9_1626 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) MY9_1630 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) MY9_1633 ENOG4105BZ9 Cytochrome C oxidase, subunit I MY9_1634 ENOG4105CCU oxidase (Subunit III) MY9_1635 ENOG41064X9 cytochrome C oxidase subunit IV MY9_1638 ENOG4106UY4 Inherit from COG: Scp-like extracellular MY9_1642 ENOG4105WUC UPF0298 protein MY9_1643 ENOG4106H78 methyltransferase MY9_1644 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) MY9_1645 ENOG4105H20 Sporulation integral membrane protein YlbJ MY9_1646 ENOG4105D78 K07001 NTE family protein MY9_1647 ENOG41063PX domain protein MY9_1648 ENOG4105CDE UPF0348 protein MY9_1650 ENOG4105KNH Nucleic acid-binding protein MY9_1656 ENOG4108V6E Cell division protein mraZ MY9_1657 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) MY9_1659 ENOG4105CJN penicillin-binding protein MY9_1660 ENOG4105CJN penicillin-binding protein MY9_1661 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) MY9_1663 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) MY9_1664 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) MY9_1665 ENOG4105CNI cell division protein FtsW MY9_1666 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) MY9_1667 ENOG4105D4A Cell wall formation (By similarity) MY9_1668 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) MY9_1669 ENOG4108R2U division initiation protein MY9_1671 ENOG4105K67 small basic protein MY9_1672 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) MY9_1673 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) MY9_1675 ENOG4105FFI sigma-e processing peptidase spoiiga MY9_1676 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) MY9_1678 ENOG4105DKW ABC transporter MY9_1680 ENOG4105WR5 sporulation protein, YlmC YmxH family MY9_1682 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase MY9_1683 ENOG4105DFA alanine racemase domain protein MY9_1684 ENOG4105VR5 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity) MY9_1685 ENOG41067XK integral membrane protein MY9_1686 ENOG4105DBK s4 domain protein MY9_1688 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) MY9_1691 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) MY9_1692 ENOG4105C34 Pseudouridine synthase MY9_1693 ENOG4108UK1 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity) MY9_1695 ENOG4105CXT aspartate transcarbamylase MY9_1697 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain MY9_1698 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain MY9_1699 ENOG4105DF0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity) MY9_1700 ENOG4107RY0 Catalyzes the conversion of dihydroorotate to orotate (By similarity) MY9_1701 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) MY9_1702 ENOG41065E1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) MY9_1703 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) MY9_1705 ENOG4107S4M Sulfate adenylate transferase MY9_1706 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) MY9_1707 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) MY9_1708 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein MY9_1709 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein MY9_1710 ENOG4105F23 Fibronectin-binding protein MY9_1712 ENOG4105DSJ YicC domain protein MY9_1713 ENOG4105KC4 UPF0296 protein MY9_1714 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) MY9_1716 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase MY9_1717 ENOG4105C25 Primosomal protein n' MY9_1718 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) MY9_1719 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) MY9_1720 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B MY9_1721 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs MY9_1722 ENOG4108ZF3 Phosphatase MY9_1723 ENOG4105D9P serine threonine protein kinase MY9_1724 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) MY9_1725 ENOG4105DJV ribulose-phosphate 3-epimerase MY9_1726 ENOG4105FJ0 thiamine MY9_1728 ENOG4105VB9 50S ribosomal protein l28 MY9_1729 ENOG4108ZAA Alkaline-shock protein MY9_1730 ENOG4105DP4 dak2 domain fusion protein ylov MY9_1732 ENOG4105EJQ L-serine dehydratase MY9_1733 ENOG4105CB5 ATP-dependent DNA helicase recG MY9_1734 ENOG4108VVV Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity) MY9_1736 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase MY9_1737 ENOG4105CHR reductase MY9_1738 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) MY9_1739 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) MY9_1740 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) MY9_1741 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) MY9_1743 ENOG4105VBN Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein (By similarity) MY9_1745 ENOG4105K5M 30s ribosomal protein S16 MY9_1746 ENOG4108BW8 UPF0109 protein MY9_1748 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) MY9_1749 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) MY9_1750 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) MY9_1751 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) MY9_1752 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) MY9_1754 ENOG4105VM1 flagellar MY9_1755 ENOG4105CMV Succinyl-CoA synthetase subunit beta MY9_1756 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha MY9_1757 ENOG4105C79 DNA protecting protein DprA MY9_1758 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) MY9_1759 ENOG4107QXI Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity) MY9_1760 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) MY9_1761 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) MY9_1762 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) MY9_1765 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) MY9_1766 ENOG4108ZC9 flagellar basal-body rod protein flgc MY9_1767 ENOG4105VQ0 flagellar hook-basal body complex protein fliE MY9_1768 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) MY9_1769 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) MY9_1772 ENOG4106YF4 Flagellar biosynthesis chaperone MY9_1774 ENOG410696Y Flagellar hook-length control protein MY9_1775 ENOG410822I Flagellar hook capping protein MY9_1776 ENOG4108JQA flagellar MY9_1777 ENOG41068WV flagellar FlbD family protein MY9_1779 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) MY9_1780 ENOG4105DD5 Flagellar motor switch protein MY9_1781 ENOG4107YTP response regulator receiver protein MY9_1783 ENOG4105CN7 Flagellar biosynthetic protein FliP MY9_1784 ENOG4105VS8 Flagellar biosynthetic protein fliq MY9_1785 ENOG4105D19 Role in flagellar biosynthesis (By similarity) MY9_1786 ENOG4105D00 flagellar biosynthetic protein flhB MY9_1787 ENOG4105D7B Flagellar biosynthesis protein flha MY9_1788 ENOG4105FZW flagellar biosynthesis regulator FlhF MY9_1790 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) MY9_1791 ENOG4105CBS Chea signal transduction histidine kinase MY9_1792 ENOG410807Z Modulation of CheA activity in response to attractants (Chemotaxis MY9_1795 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) MY9_1796 ENOG4105CE9 30S ribosomal protein S2 MY9_1797 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) MY9_1799 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) MY9_1800 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) MY9_1801 ENOG4105KNE Phosphatidate cytidylyltransferase MY9_1803 ENOG4105DZP Membrane-associated zinc metalloprotease MY9_1804 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) MY9_1805 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) MY9_1806 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) MY9_1807 ENOG4105CHV Transcription elongation factor NusA MY9_1808 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination MY9_1809 ENOG4105VHM ribosomal protein MY9_1810 ENOG4107EEM One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) MY9_1811 ENOG4105W7A Protein of unknown function (DUF503) MY9_1812 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) MY9_1813 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) MY9_1814 ENOG4105DTN riboflavin biosynthesis protein ribF MY9_1815 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) MY9_1816 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) MY9_1818 ENOG4105C1V Peptidase, M16 MY9_1821 ENOG4105E35 Dipicolinate synthase subunit A MY9_1822 ENOG4108S0H Dipicolinic acid synthetase, b subunit MY9_1823 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) MY9_1825 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) MY9_1827 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit MY9_1829 ENOG4105CNU cell division protein FtsK MY9_1830 ENOG4105FDP GntR family transcriptional regulator MY9_1834 ENOG4108RKS Short-chain dehydrogenase reductase Sdr MY9_1835 ENOG4105XZV Protein of unknown function (DUF3243) MY9_1838 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase MY9_1839 ENOG4105CEV competence damage-inducible protein MY9_1841 ENOG4108A04 Beta-lactamase MY9_1842 ENOG4105E4Y Endoribonuclease that initiates mRNA decay (By similarity) MY9_1843 ENOG4105D48 metallophosphoesterase MY9_1844 ENOG4105MCT stage V sporulation protein S MY9_1846 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) MY9_1847 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) MY9_1850 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) MY9_1851 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) MY9_1857 ENOG4105IIP Membrane MY9_1858 ENOG4105W1N transcriptional regulator MY9_1859 ENOG4108151 Beta-lactamase domain protein MY9_1860 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase MY9_1862 ENOG4107QKG PfaD family MY9_1863 ENOG41062T2 Acyl carrier protein MY9_1864 ENOG4108MH3 Polyketide beta-ketoacyl acyl carrier protein synthase MY9_1865 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase MY9_1866 ENOG4108MGH Enoyl-CoA hydratase MY9_1867 ENOG4108KQ6 Enoyl-CoA hydratase MY9_1868 ENOG4105C0W non-ribosomal peptide synthetase MY9_1869 ENOG4107SQU synthase MY9_1871 ENOG4105C0W non-ribosomal peptide synthetase MY9_1873 ENOG4106A3M Cytochrome p-450 MY9_1876 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin MY9_1878 ENOG4105K7W phage-related replication protein MY9_1879 ENOG4108X3M OsmC Ohr family protein MY9_1880 ENOG410814C multidrug resistance protein MY9_1884 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) MY9_1885 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) MY9_1888 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) MY9_1889 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) MY9_1890 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) MY9_1891 ENOG4105U6W MutT NUDIX family protein MY9_1892 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase MY9_1896 ENOG4106F1P AAA ATPase, central domain protein MY9_1897 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) MY9_1898 ENOG4105CXI aluminum resistance protein MY9_1899 ENOG4105KV4 Transcriptional regulator MY9_1900 ENOG4105C5F glutamine synthetase MY9_1903 ENOG4106BHF MY9_1906 ENOG4106ANW SMI1_KNR4 MY9_1907 ENOG4106BHF MY9_1914 ENOG4105CT4 transporter MY9_1915 ENOG4105DSG hydrolase family 43 MY9_1917 ENOG4105C93 Xylose Isomerase MY9_1918 ENOG4105CMG Carbohydrate kinase MY9_1920 ENOG4107Y9E nuclease MY9_1921 ENOG4105C54 Major Facilitator superfamily MY9_1922 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) MY9_1925 ENOG4107YUK This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity) MY9_1928 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) MY9_1940 ENOG4108Q8B Spore germination protein MY9_1941 ENOG4108NHD germination protein MY9_1944 ENOG4105FVX MY9_1946 ENOG4105K7W phage-related replication protein MY9_1948 ENOG4105I9P Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity) MY9_1950 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) MY9_1952 ENOG4108SVB resolvase MY9_1953 ENOG4105VPS UPF0291 protein MY9_1954 ENOG4105CV1 Transketolase (EC 2.2.1.1) MY9_1958 ENOG4107QIV Cytochrome c biogenesis protein MY9_1963 ENOG4107DZX Small, acid-soluble spore protein P MY9_1965 ENOG4108I0Z Aconitate hydratase MY9_1966 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen MY9_1969 ENOG41067CD Small, acid-soluble spore protein Tlp MY9_1971 ENOG4105MI2 MY9_1972 ENOG4105W8X HesB YadR YfhF-family protein MY9_1973 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) MY9_1974 ENOG4105K4P CoA-binding domain protein MY9_1975 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) MY9_1982 ENOG4108MYR Secreted protein MY9_1983 ENOG4107SYN Glycosyl hydrolases family 43 MY9_1985 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase MY9_1986 ENOG4107T5V SNARE associated Golgi MY9_1988 ENOG4107QX3 carboxylase MY9_1989 ENOG4105E39 Enoyl-CoA hydratase MY9_1990 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase MY9_1991 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit MY9_1992 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase MY9_1993 ENOG4105CEY Amp-dependent synthetase and ligase MY9_1994 ENOG4105C1G acyl-Coa dehydrogenase MY9_1997 ENOG4105F32 YngK protein MY9_1998 ENOG4106U2H Protein of unknown function (DUF1360) MY9_2000 ENOG4105CEY Amp-dependent synthetase and ligase MY9_2001 ENOG4105C0W non-ribosomal peptide synthetase MY9_2003 ENOG4105C0W non-ribosomal peptide synthetase MY9_2004 ENOG4107RVU D-Ala-D-Ala carboxypeptidase 3 (S13) family MY9_2005 ENOG4108N2V aldose 1-epimerase MY9_2006 ENOG4107QJQ Mate efflux family protein MY9_2011 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) MY9_2012 ENOG4105SKE transcriptional Regulator LysR family MY9_2013 ENOG4105CB2 alcohol dehydrogenase MY9_2014 ENOG4105BZ8 glutamate synthase MY9_2015 ENOG4105CBC glutamate synthase MY9_2016 ENOG4105C5Q Transcriptional regulator MY9_2017 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) MY9_2018 ENOG4105II7 pyrroline-5-carboxylate reductase MY9_2021 ENOG4108UB7 MY9_2022 ENOG41068WN MY9_2023 ENOG4105IE8 Alpha-ketoglutarate permease MY9_2024 ENOG4107U6E carbohydrate kinase FGGY MY9_2025 ENOG4108M3J Dehydrogenase MY9_2026 ENOG4108J2R molybdopterin oxidoreductase MY9_2033 ENOG4105EC8 Methyl-accepting chemotaxis MY9_2035 ENOG4108YQE rare lipoprotein a MY9_2036 ENOG4105XPP Protein of unknown function (DUF1275) MY9_2037 ENOG4108NR7 pectate lyase MY9_2039 ENOG4108RAV Conserved protein MY9_2041 ENOG4105F0F Oxalate decarboxylase MY9_2043 ENOG4105EPI acetyltransferase, (GNAT) family MY9_2046 ENOG41073R8 VanW family MY9_2048 ENOG4105VMP Transcriptional regulator MY9_2049 ENOG4105NX3 Membrane MY9_2051 ENOG4108Q5Y Membrane MY9_2057 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) MY9_2066 ENOG4107T94 Endo-14-beta-xylanase MY9_2067 ENOG4108J9Q DNA ligase MY9_2080 ENOG4105CBZ Short-chain dehydrogenase reductase Sdr MY9_2084 ENOG4108Z7R Chaperone CsaA MY9_2085 ENOG4105FTV AraC Family Transcriptional Regulator MY9_2086 ENOG4108HJF gCN5-related N-acetyltransferase MY9_2088 ENOG4108W8B Beta-lactamase domain protein MY9_2090 ENOG4105D29 Helix-turn-helix type 11 domain protein MY9_2092 ENOG4105KTU Transcriptional regulator, arsr family MY9_2094 ENOG4108SJC Membrane MY9_2098 ENOG4105ECK Fatty Acid Desaturase MY9_2099 ENOG4108ZGX Histidine kinase MY9_2100 ENOG4108S01 response regulator MY9_2102 ENOG41069ER domain protein MY9_2103 ENOG4105C9U ATP-dependent DNA helicase RecQ MY9_2104 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) MY9_2105 ENOG4105SCY DNAK suppressor MY9_2113 ENOG4105C26 Dehydrogenase MY9_2114 ENOG4105EWU Squalene--hopene cyclase MY9_2115 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) MY9_2116 ENOG4105C8J )-transporter MY9_2117 ENOG4105C09 Bile acid MY9_2118 ENOG4105C7S Dehydrogenase MY9_2120 ENOG4107T89 von Willebrand factor, type A MY9_2121 ENOG4105GMT ATPase associated with various cellular activities aaa_5 MY9_2123 ENOG4105K4H Nlp p60 protein MY9_2125 ENOG41087PP glycosyltransferase MGT family MY9_2127 ENOG4107QMU Mate efflux family protein MY9_2128 ENOG4106SCS STAS domain MY9_2132 ENOG4105FR1 rard protein MY9_2135 ENOG4105C6Z Gluconate MY9_2137 ENOG41090U3 tautomerase MY9_2140 ENOG4105FBA Phospholipase Carboxylesterase MY9_2143 ENOG4105E1V na solute symporter MY9_2147 ENOG4108VXD carboxy-peptidase MY9_2148 ENOG4105D3A purine nucleoside phosphorylase DeoD-type MY9_2151 ENOG4106Z5R MY9_2157 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein MY9_2158 ENOG4108TSC N-acetyltransferase MY9_2159 ENOG4107S4Y M20 DapE family protein YgeY MY9_2162 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) MY9_2170 ENOG4107T32 3-phytase (EC 3.1.3.8) MY9_2171 ENOG4105C5E polysaccharide biosynthesis protein MY9_2172 ENOG4105E0X reductase MY9_2173 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) MY9_2177 ENOG4105QZP Uncharacterized protein conserved in bacteria (DUF2140) MY9_2178 ENOG41090WU lipolytic protein G-D-S-L family MY9_2179 ENOG4108KF3 Electron transport protein SCO1 SenC MY9_2181 ENOG4105C7B Threonine dehydratase MY9_2183 ENOG4108UT2 hemolysin iii MY9_2185 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) MY9_2187 ENOG4107YX5 Pfam:DUF548 MY9_2188 ENOG4108Y6J UPF0403 protein MY9_2189 ENOG4105C01 Dihydroxy-acid dehydratase MY9_2192 ENOG4108V06 Glutathione peroxidase MY9_2193 ENOG4105CVG Homoserine O-transsuccinylase MY9_2202 ENOG41081VK Ribonuclease MY9_2207 ENOG410890F Dynamin family MY9_2209 ENOG41065KQ synthase MY9_2210 ENOG4105C2W permease MY9_2211 ENOG4108UPS Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity) MY9_2212 ENOG4105CTD carboxy-peptidase MY9_2213 ENOG4105CAX The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity) MY9_2214 ENOG4108UHU Aldolase MY9_2215 ENOG4105D7K pfkb domain protein MY9_2216 ENOG4108M60 Transcriptional regulator MY9_2218 ENOG4105CHR reductase MY9_2219 ENOG4105DVT helicase MY9_2221 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) MY9_2223 ENOG4108UKS UPF0398 protein MY9_2226 ENOG4107X2U Inherit from COG: Exonuclease-like protein MY9_2227 ENOG4108I5C dEAD DEAH box helicase MY9_2237 ENOG4105BZ4 penicillin-binding protein MY9_2239 ENOG4105CSM endonuclease III MY9_2241 ENOG4105C5S asparaginyl-tRNA synthetase MY9_2242 ENOG4105CHM Aminotransferase MY9_2244 ENOG4105YAC MY9_2245 ENOG4105DVT helicase MY9_2246 ENOG4108Z2X Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity) MY9_2247 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) MY9_2248 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) MY9_2249 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase MY9_2250 ENOG4105DJ0 Poly(A) Polymerase MY9_2251 ENOG4105CPK Glycosyl transferase (Group 1 MY9_2252 ENOG4105FJR Lmbe family MY9_2253 ENOG4108Z5K methylglyoxal synthase MY9_2254 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) MY9_2255 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase MY9_2256 ENOG4108JYZ YitT family MY9_2260 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) MY9_2264 ENOG41068YB TPR repeat-containing protein MY9_2266 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase MY9_2268 ENOG4105CIH Imidazole acetol-phosphate transaminase MY9_2270 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) MY9_2271 ENOG4108ZGB N-(5'-phosphoribosyl)anthranilate isomerase MY9_2273 ENOG4108I0Q anthranilate phosphoribosyltransferase MY9_2274 ENOG4105CRQ synthase (Component I) MY9_2275 ENOG4105KHN chorismate mutase MY9_2276 ENOG4105D49 3-dehydroquinate synthase MY9_2277 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase MY9_2278 ENOG4105BZU Histidine kinase MY9_2280 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) MY9_2281 ENOG4105EAH synthase MY9_2282 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) MY9_2283 ENOG4105XXQ heptaprenyl diphosphate synthase component I MY9_2285 ENOG4105EUJ GTP cyclohydrolase i MY9_2287 ENOG4105K70 DNA-binding protein MY9_2288 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) MY9_2291 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase MY9_2292 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) MY9_2293 ENOG41065D1 MY9_2294 ENOG4105S2F MY9_2297 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) MY9_2298 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) MY9_2299 ENOG4105CAT Cytidine monophosphate kinase MY9_2302 ENOG4105MSI germination protein ypeb MY9_2304 ENOG4108PNU Involved in the degradation of specific anti-sigma factors (By similarity) MY9_2305 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase MY9_2309 ENOG4107RGJ metallophosphoesterase MY9_2312 ENOG4105I7S Abortive infection protein MY9_2313 ENOG4105C9U ATP-dependent DNA helicase RecQ MY9_2314 ENOG4105T7X MY9_2316 ENOG4108SAX Membrane MY9_2319 ENOG4108JQ1 Dehydrogenase MY9_2320 ENOG4105FF2 Type I DHQase MY9_2323 ENOG4105BZU Histidine kinase MY9_2324 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MY9_2325 ENOG4105CRE cytochrome C MY9_2326 ENOG4107TWT Cytochrome c biogenesis protein MY9_2329 ENOG4105FE9 pseudouridine synthase MY9_2331 ENOG4108JIC nucleoside recognition domain protein MY9_2332 ENOG4105DZ1 carboxypeptidase MY9_2334 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) MY9_2335 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) MY9_2338 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) MY9_2339 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) MY9_2340 ENOG4108R6K riboflavin synthase, subunit alpha MY9_2341 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) MY9_2344 ENOG4105C3F Signal peptidase i MY9_2346 ENOG4105VES Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) MY9_2350 ENOG4107ZE5 PPIases accelerate the folding of proteins MY9_2351 ENOG4105PTM secreted protein MY9_2352 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) MY9_2354 ENOG4105G6R Stage v sporulation protein ae MY9_2356 ENOG4105CZ3 stage V sporulation protein ad MY9_2357 ENOG41090VF Stage v sporulation protein ac MY9_2360 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) MY9_2361 ENOG4108ZBE Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity) MY9_2362 ENOG41082AN stage II sporulation protein MY9_2363 ENOG4105DZ1 carboxypeptidase MY9_2364 ENOG4105CB1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) MY9_2365 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) MY9_2366 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) MY9_2368 ENOG4105I3K Ferric uptake regulator, Fur family MY9_2369 ENOG4105MZ9 stage II sporulation protein m MY9_2372 ENOG4105DFD Na H antiporter MY9_2373 ENOG4108IJ0 Aspartate ammonia-lyase MY9_2374 ENOG4105HDK L-asparaginase MY9_2375 ENOG4108IMY Transcriptional regulator MY9_2377 ENOG4108YZ4 nudix hydrolase MY9_2379 ENOG4105CPC Aldo Keto reductase MY9_2383 ENOG4106HZJ MY9_2384 ENOG4105RHY Pfam:UPF0157 MY9_2385 ENOG4105KAC Antibiotic biosynthesis monooxygenase MY9_2386 ENOG4108XET gCN5-related N-acetyltransferase MY9_2388 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) MY9_2391 ENOG4105E5W Transporter MY9_2393 ENOG4105HRU Glyoxalase Bleomycin resistance protein (Dioxygenase MY9_2396 ENOG4108IXY short-chain dehydrogenase reductase MY9_2397 ENOG41069FQ Metallo-beta-lactamase superfamily MY9_2398 ENOG4105II7 pyrroline-5-carboxylate reductase MY9_2400 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase MY9_2402 ENOG410861F 50S ribosomal protein L33 MY9_2403 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) MY9_2404 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase MY9_2405 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) MY9_2406 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) MY9_2408 ENOG4107XQC Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins (By similarity) MY9_2409 ENOG4108NA0 Uncharacterized conserved protein (COG2071) MY9_2410 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) MY9_2411 ENOG4108HNZ carboxyl transferase MY9_2412 ENOG4108ZVT methylmalonyl-coA epimerase MY9_2413 ENOG4108VZI ErfK ybiS ycfS ynhG family protein MY9_2414 ENOG4108QEG Membrane MY9_2415 ENOG4105CDA abc transporter atp-binding protein MY9_2416 ENOG4105E5Q amino acid AbC transporter MY9_2417 ENOG4108HW3 (ABC) transporter MY9_2418 ENOG4108Y6J UPF0403 protein MY9_2419 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) MY9_2422 ENOG4105C7S Dehydrogenase MY9_2425 ENOG4105CKM Branched-chain carboxylic acid kinase MY9_2426 ENOG4107RDP Dehydrogenase MY9_2428 ENOG4108JUB Transcriptional regulator MY9_2429 ENOG4106CCJ Protein of unknown function (DUF2627) MY9_2430 ENOG4105CR4 methylisocitrate lyase MY9_2431 ENOG4105DXD 2-methylcitrate dehydratase MY9_2433 ENOG4105C1G acyl-Coa dehydrogenase MY9_2434 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase MY9_2436 ENOG4108QXE glycerophosphoryl diester phosphodiesterase MY9_2437 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase MY9_2440 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase MY9_2443 ENOG4107QQR Sporulation MY9_2444 ENOG4105S1Z Stage IV sporulation protein B MY9_2445 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) MY9_2446 ENOG4105XBY Regulates arginine biosynthesis genes (By similarity) MY9_2447 ENOG4105DX0 Hemolysin A MY9_2450 ENOG4105CTB Polyprenyl synthetase MY9_2451 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) MY9_2452 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) MY9_2453 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) MY9_2454 ENOG4105M7K Involved in the transcription termination process (By similarity) MY9_2455 ENOG4108ZSR alkaline shock protein MY9_2456 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase MY9_2460 ENOG410644B Stage III sporulation protein af MY9_2462 ENOG4105KQ4 Stage iii sporulation protein ad MY9_2463 ENOG4108CQH stage III sporulation protein AC MY9_2464 ENOG4105KR5 Stage iii sporulation protein MY9_2465 ENOG4105CD2 stage iii sporulation protein aa MY9_2467 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) MY9_2468 ENOG4105DC7 peptidase M24 MY9_2469 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) MY9_2471 ENOG4105CBJ Metal-dependent enzyme MY9_2474 ENOG4105KST dependent repressor MY9_2475 ENOG4107S5Z Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity) MY9_2476 ENOG4105WZW rhodanese family MY9_2477 ENOG4107RGW The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MY9_2478 ENOG4107QK8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor MY9_2479 ENOG4105D43 The glycine cleavage system catalyzes the degradation of glycine (By similarity) MY9_2480 ENOG4105C0D helicase MY9_2483 ENOG4108IMY Transcriptional regulator MY9_2485 ENOG4105VFR signal peptidase MY9_2497 ENOG41080XP Cbs domain MY9_2499 ENOG4105C37 (CBS) domain MY9_2503 ENOG4105C5X domain protein MY9_2508 ENOG4105E0M Sulfatase MY9_2511 ENOG4107ZXI Rhomboid family MY9_2513 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase MY9_2518 ENOG41068DG YceG-like family MY9_2519 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) MY9_2520 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) MY9_2521 ENOG4105E2Z phosphate ABC transporter (Permease MY9_2522 ENOG4105C8U phosphate abc transporter MY9_2523 ENOG4105CVA phosphate MY9_2524 ENOG4107RF6 penicillin-binding protein MY9_2526 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) MY9_2527 ENOG4105SXS Protein of unknown function (DUF456) MY9_2530 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) MY9_2531 ENOG41063Y9 MY9_2532 ENOG4108U5J '-nucleotidase MY9_2533 ENOG4105N80 Ferric uptake regulator, Fur family MY9_2534 ENOG4108JYZ YitT family MY9_2535 ENOG41069ZM Protein of unknown function (DUF2624) MY9_2536 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) MY9_2539 ENOG4108IUH Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) MY9_2540 ENOG4105EGD dinuclear metal center protein, YbgI family MY9_2544 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) MY9_2545 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) MY9_2546 ENOG41082VT Uncharacterized BCR, YaiI/YqxD family COG1671 MY9_2547 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) MY9_2549 ENOG4105C38 Glycyl-tRNA synthetase beta subunit MY9_2550 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit MY9_2551 ENOG4106DBE Involved in DNA repair and RecF pathway recombination (By similarity) MY9_2553 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) MY9_2554 ENOG4105KG3 cytidine deaminase MY9_2555 ENOG4107YR5 Diacylglycerol kinase MY9_2556 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) MY9_2557 ENOG4105CTJ Metal Dependent Phosphohydrolase MY9_2558 ENOG4105C9A Phoh family MY9_2559 ENOG4105EI1 sporulation protein yqfd MY9_2560 ENOG41068P3 sporulation protein YqfC MY9_2562 ENOG4105DI5 UPF0365 protein MY9_2563 ENOG4105F7J membrane-bound serine protease MY9_2564 ENOG4105KTH gatB Yqey MY9_2567 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) MY9_2568 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) MY9_2569 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) MY9_2572 ENOG4105CFG Acts as a chaperone (By similarity) MY9_2573 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ MY9_2574 ENOG4105CI8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity) MY9_2575 ENOG4105CSA Coproporphyrinogen iii oxidase MY9_2576 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) MY9_2578 ENOG4108ZRV stage ii sporulation protein p MY9_2579 ENOG4105CEF Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity) MY9_2580 ENOG41082YS Binds directly to 16S ribosomal RNA MY9_2581 ENOG4105TQK DNA polymerase iii, delta' subunit MY9_2583 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 MY9_2584 ENOG4108UK2 deaminase MY9_2585 ENOG4105KQC Competence protein MY9_2587 ENOG4108D32 Methyltransferase MY9_2589 ENOG4108WF2 Metal Dependent Phosphohydrolase MY9_2590 ENOG4108Z1W Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) MY9_2591 ENOG410812S Rna-binding protein MY9_2592 ENOG4105E2X shikimate dehydrogenase MY9_2593 ENOG4105CQW ribosome biogenesis GTPase YqeH MY9_2594 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase MY9_2597 ENOG41080BT SNARE associated Golgi MY9_2600 ENOG4105WFK nuclease MY9_2601 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) MY9_2607 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) MY9_2614 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) MY9_2618 ENOG41067XF inhibitor MY9_2623 ENOG4105KR8 Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) MY9_2625 ENOG41087NI Sulfite exporter TauE/SafE MY9_2626 ENOG4105VFE sira family MY9_2627 ENOG4107TPS domain protein MY9_2628 ENOG4105VFE sira family MY9_2629 ENOG4105C72 UPF0176 protein MY9_2630 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase MY9_2631 ENOG4105XTG Pfam:DUF156 MY9_2632 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein MY9_2633 ENOG41090E6 transcriptional regulator MERR family MY9_2640 ENOG4105XRQ Xanthine dehydrogenase accessory factor MY9_2643 ENOG4105H3G oxidoreductase MY9_2644 ENOG4105PGM cation diffusion facilitator family transporter MY9_2646 ENOG4105ETE Transcriptional regulator (LacI family MY9_2647 ENOG41066EA baseplate J family protein MY9_2649 ENOG41064BW Protein of unknown function (DUF2568) MY9_2654 ENOG41075D4 Aminoglycoside 6-adenylyltransferase MY9_2656 ENOG4105EA8 2-Nitropropane dioxygenase MY9_2657 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) MY9_2660 ENOG4107YCY Transcriptional regulator MY9_2663 ENOG4105CHR reductase MY9_2664 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) MY9_2665 ENOG4105CV1 Transketolase (EC 2.2.1.1) MY9_2666 ENOG4105C0R drug resistance transporter emrb qaca subfamily MY9_2667 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes MY9_2668 ENOG4108MEK Metal-binding protein YodA MY9_2670 ENOG41083Q9 chitosanase MY9_2672 ENOG4105X5K response regulator receiver protein MY9_2673 ENOG4108VQT Alpha beta hydrolase fold protein MY9_2674 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein MY9_2675 ENOG4106H77 Inherit from COG: SH3 type 3 domain-containing protein MY9_2677 ENOG4105Z0X Glyoxalase Bleomycin resistance protein (Dioxygenase MY9_2679 ENOG4105PGS Spore coat protein MY9_2680 ENOG4105E2A Dehydrogenase MY9_2683 ENOG4108HKT sucrose-6-phosphate hydrolase MY9_2684 ENOG4105F3R pts system mannose fructose sorbose family iid MY9_2685 ENOG4105ETZ PTS System MY9_2686 ENOG4108IQ3 PTS system MY9_2687 ENOG4105YHU PTS system MY9_2688 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family MY9_2689 ENOG4105C85 amino acid MY9_2690 ENOG4105N14 lysine exporter protein LysE YggA MY9_2691 ENOG4108NGU Transcriptional regulator MY9_2692 ENOG4105JVQ RNA Polymerase MY9_2693 ENOG4108P49 AntiSigma factor MY9_2694 ENOG4105EXC Acyl-transferase MY9_2695 ENOG4105WDR MY9_2696 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) MY9_2697 ENOG41082JN Transcriptional regulator MY9_2702 ENOG4105TMB Formate nitrite transporter MY9_2703 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) MY9_2706 ENOG4105C28 cystathionine MY9_2709 ENOG4108WVK Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity) MY9_2712 ENOG4107XRG penicillin-binding protein MY9_2713 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) MY9_2714 ENOG4105DBI uridine monophosphokinase MY9_2715 ENOG4105CFP Peptidase U32 MY9_2716 ENOG4105XYU peptidase (U32 family) MY9_2717 ENOG4108VQJ O-methyltransferase MY9_2718 ENOG4105HHA aminodeoxychorismate lyase MY9_2719 ENOG4105VPH UPF0473 protein MY9_2720 ENOG4108Z08 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) MY9_2721 ENOG4105VBH UPF0297 protein MY9_2722 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) MY9_2723 ENOG4105C02 permease MY9_2726 ENOG41060CR MY9_2728 ENOG4105C7H Helicase, RecD TraA family MY9_2730 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) MY9_2731 ENOG4105C3J Cysteine desulfurase MY9_2733 ENOG4105D1H recombination factor protein RarA MY9_2734 ENOG4105CUZ uba thif-type nad fad binding protein MY9_2736 ENOG4105C9M aspartyl-trna synthetase MY9_2737 ENOG4105CUT histidyl-tRNA synthetase MY9_2740 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase MY9_2742 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) MY9_2743 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) MY9_2744 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) MY9_2745 ENOG41067VP Protein of unknown function (DUF1049) MY9_2746 ENOG4105NCW Trka-c domain protein MY9_2747 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) MY9_2749 ENOG4105CKP Polysaccharide Biosynthesis Protein MY9_2750 ENOG4108QG2 Membrane MY9_2751 ENOG4105NAP MY9_2752 ENOG4105VIE preprotein translocase, subunit YajC MY9_2753 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) MY9_2754 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) MY9_2755 ENOG41061AI Protein of unknown function (DUF2905) MY9_2756 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) MY9_2757 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) MY9_2759 ENOG4105IE8 Alpha-ketoglutarate permease MY9_2760 ENOG4105CK5 oxidoreductase MY9_2764 ENOG4105BZG amino acid carrier protein MY9_2765 ENOG4105CDY transcriptional regulatory protein MY9_2767 ENOG4106678 morphogenetic protein associated with SpoVID MY9_2768 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) MY9_2769 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase MY9_2770 ENOG4108IYU L-aspartate oxidase MY9_2773 ENOG4105CQC Prephenate dehydratase MY9_2774 ENOG41090I5 UPF0735 ACT domain-containing protein MY9_2775 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control MY9_2778 ENOG4105K46 50S ribosomal protein l27 MY9_2779 ENOG4105X36 (ribosomal) protein MY9_2780 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) MY9_2783 ENOG4107QMS site-determining protein MY9_2784 ENOG4107YDG Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) MY9_2785 ENOG4105YHC Rod shape-determining protein MreD MY9_2786 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) MY9_2787 ENOG4105DFF Rod shape-determining protein mreb MY9_2788 ENOG4105W5Q DNA repair protein (RadC MY9_2789 ENOG4108Z03 MAF-like protein MY9_2791 ENOG4106A3R peptidase MY9_2792 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase MY9_2793 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) MY9_2795 ENOG4106AR7 Spore coat protein MY9_2796 ENOG41068KH stage VI sporulation protein D MY9_2797 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase MY9_2798 ENOG4105D52 delta-aminolevulinic acid dehydratase MY9_2800 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) MY9_2802 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) MY9_2804 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) MY9_2805 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) MY9_2806 ENOG4108IUQ atp-dependent protease MY9_2807 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) MY9_2808 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation MY9_2811 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) MY9_2812 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) MY9_2813 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) MY9_2814 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) MY9_2815 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase MY9_2816 ENOG4108ZP8 Acetolactate synthase small subunit MY9_2817 ENOG4105C7K acetolactate synthase MY9_2822 ENOG4105I4A GCN5-related N-acetyltransferase MY9_2824 ENOG4107KM7 Heat induced stress protein YflT MY9_2825 ENOG4105M59 Phosphodiesterase, mj0936 family MY9_2826 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) MY9_2827 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) MY9_2828 ENOG4108XJQ germination protein MY9_2829 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) MY9_2831 ENOG41067TZ transcriptional regulator, MarR family MY9_2832 ENOG4105PFC Transcriptional regulator MY9_2834 ENOG4105E33 succinate dehydrogenase MY9_2836 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit MY9_2838 ENOG4105CFH Aspartokinase MY9_2839 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) MY9_2840 ENOG4105K63 Thioredoxin MY9_2841 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) MY9_2842 ENOG4105C10 Electron transfer flavoprotein MY9_2843 ENOG4105BZJ Electron transfer flavoprotein MY9_2844 ENOG41060WC Enoyl-CoA hydratase MY9_2845 ENOG4107Z3H Transcriptional regulator, TetR family MY9_2846 ENOG4105CEY Amp-dependent synthetase and ligase MY9_2847 ENOG4105C98 muts2 protein MY9_2848 ENOG4105DCG PHP domain protein MY9_2851 ENOG4107FSS Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) MY9_2852 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) MY9_2853 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) MY9_2854 ENOG4108RWN rrna methyltransferase MY9_2855 ENOG41067MF small acid-soluble spore protein MY9_2857 ENOG4105CQB FAD linked oxidase domain protein MY9_2858 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) MY9_2863 ENOG4105K7K Transcriptional regulator MY9_2864 ENOG4105CZZ Alpha-N-arabinofuranosidase (EC 3.2.1.55) MY9_2865 ENOG4105DRS transport system, permease MY9_2868 ENOG4108MDK Dehydrogenase MY9_2870 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase MY9_2871 ENOG4105EF1 ribulokinase MY9_2874 ENOG4107PMW Arabinan endo-1,5-alpha-L-arabinosidase MY9_2875 ENOG4105CN9 Peptidase m42 family protein MY9_2877 ENOG410696E Membrane MY9_2878 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) MY9_2879 ENOG4105VJV 50s ribosomal protein L35 MY9_2880 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) MY9_2881 ENOG41067MG lrgb family MY9_2883 ENOG4105DY9 regulatoR MY9_2884 ENOG4108HRK Histidine kinase MY9_2885 ENOG4105U0R haloacid dehalogenase-like hydrolase MY9_2886 ENOG4105C22 threonyL-tRNA synthetase MY9_2887 ENOG4108TDW sporulation protein YtxC MY9_2891 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) MY9_2892 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) MY9_2893 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase MY9_2894 ENOG4105KVH Transcriptional regulator MY9_2895 ENOG4105F27 Major Facilitator MY9_2896 ENOG4105CV8 reductase MY9_2897 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) MY9_2899 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) MY9_2900 ENOG4105C2M dna polymerase I MY9_2901 ENOG4105BZU Histidine kinase MY9_2902 ENOG4105DPZ Two component transcriptional regulator (Winged helix family MY9_2904 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) MY9_2905 ENOG4108HMX isocitrate dehydrogenase (NADP) MY9_2906 ENOG4105BZN citrate synthase MY9_2909 ENOG4108REF Sporulation integral membrane protein ytvi MY9_2910 ENOG4105FS0 cytoplasmic membrane protein MY9_2911 ENOG4105CA9 Pyruvate kinase MY9_2912 ENOG4105CTQ phosphohexokinase MY9_2915 ENOG4108IEY Carboxyl transferase domain MY9_2916 ENOG4105C6K Malic enzyme MY9_2917 ENOG4105C0B DNA polymerase III (alpha subunit) MY9_2919 ENOG4105VV2 MY9_2921 ENOG4106EVM MY9_2922 ENOG4105SFS phosphoesterase RecJ domain protein MY9_2926 ENOG410635A Membrane MY9_2927 ENOG4105CH2 amidohydrolase MY9_2931 ENOG4105DEN Luciferase family MY9_2932 ENOG4105CDA abc transporter atp-binding protein MY9_2937 ENOG4108XSB acetyltransferase, (GNAT) family MY9_2938 ENOG4108KSA LysR family transcriptional regulator MY9_2939 ENOG4105E8R UPF0173 metal-dependent hydrolase MY9_2942 ENOG4105CH7 arginosuccinase MY9_2943 ENOG4105CDH Citrulline--aspartate ligase MY9_2944 ENOG4105EPU Molybdenum cofactor synthesis domain protein MY9_2945 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) MY9_2948 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) MY9_2949 ENOG4105KBJ sporulation protein ytfj MY9_2951 ENOG4105VK3 rdd domain containing protein MY9_2952 ENOG4105D07 Signal peptide peptidase, SppA MY9_2954 ENOG4108KKH Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) MY9_2955 ENOG4105EFZ amidohydrolase MY9_2956 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) MY9_2963 ENOG4105U5Y Transcriptional regulator MY9_2965 ENOG4105BZU Histidine kinase MY9_2967 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) MY9_2969 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) MY9_2972 ENOG4105F1V Acetoin utilization protein MY9_2973 ENOG4105W87 Cbs domain MY9_2974 ENOG4105DGU Histone deacetylase MY9_2975 ENOG4105ER2 Ompa motb domain protein MY9_2976 ENOG4107R0U MotA TolQ exbB proton channel MY9_2977 ENOG4105ETE Transcriptional regulator (LacI family MY9_2978 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase MY9_2982 ENOG4105DFU Cell wall formation (By similarity) MY9_2984 ENOG4108VDD TRNA binding domain protein MY9_2988 ENOG4108V0E nucleoside 2-deoxyribosyltransferase YtoQ MY9_2991 ENOG4105C6K Malic enzyme MY9_2992 ENOG4105C8F Beta-lactamase domain protein MY9_2993 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) MY9_2995 ENOG4108V15 phosphotransferase enzyme family MY9_2996 ENOG4108IUM Glycogen debranching enzyme MY9_2999 ENOG4107F58 2'-5' rna ligase MY9_3000 ENOG4105C6T cysteine synthase MY9_3001 ENOG4107QSE Dipeptidase MY9_3002 ENOG4105C7N Xanthine uracil vitamin C permease MY9_3005 ENOG4105YW5 deoR family transcriptional regulator MY9_3008 ENOG4105CBX hi0933 family MY9_3009 ENOG4105C94 Transporter MY9_3011 ENOG4105MU9 integral membrane protein MY9_3012 ENOG4105DDC Oxidoreductase domain protein MY9_3014 ENOG4105F5H Glycosyl Hydrolase Family 88 MY9_3016 ENOG41075H3 AraC family transcriptional regulator MY9_3018 ENOG4105C50 Binding-protein-dependent transport systems, inner membrane component MY9_3020 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) MY9_3022 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) MY9_3023 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) MY9_3026 ENOG4105NTD Inherit from COG: Hydrolase MY9_3029 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component MY9_3030 ENOG4105I1K ABC transporter MY9_3032 ENOG41085GJ domain protein MY9_3033 ENOG4105C8T Leucyl-tRNA synthetase MY9_3036 ENOG4105BZU Histidine kinase MY9_3037 ENOG410605W Major Facilitator MY9_3038 ENOG4106UBQ MY9_3040 ENOG4105C19 ABC transporter MY9_3041 ENOG4105EWM Histidine kinase MY9_3043 ENOG4107R34 abc transporter permease protein MY9_3044 ENOG4105C19 ABC transporter MY9_3047 ENOG4105DVE abc transporter atp-binding protein MY9_3048 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family MY9_3051 ENOG4105N5T Radical SAM Protein MY9_3054 ENOG4105E8V Alpha Beta Hydrolase Fold protein MY9_3055 ENOG4108Z0R Transferase MY9_3056 ENOG4105C85 amino acid MY9_3057 ENOG4105CAQ asparagine synthetase MY9_3058 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP MY9_3059 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase MY9_3062 ENOG4105D2X ABC transporter substrate-binding protein MY9_3064 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component MY9_3068 ENOG4108RMU ferritin dps family protein MY9_3071 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) MY9_3072 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) MY9_3073 ENOG4108V2W Carbonate dehydratase MY9_3078 ENOG4105CC5 ABC transporter MY9_3079 ENOG4105CC5 ABC transporter MY9_3080 ENOG4105DIK (ABC) transporter MY9_3081 ENOG4105DSE periplasmic solute binding protein MY9_3082 ENOG4105DTQ mandelate racemase muconate lactonizing MY9_3083 ENOG4105CEY Amp-dependent synthetase and ligase MY9_3084 ENOG4108IPT Naphthoate synthase MY9_3085 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) MY9_3086 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) MY9_3087 ENOG4105E4F Isochorismate synthase MY9_3093 ENOG4108IAJ Nad-dependent epimerase dehydratase MY9_3094 ENOG4107SBE Glycosyl transferase (Group 1 MY9_3097 ENOG4107SBE Glycosyl transferase (Group 1 MY9_3098 ENOG4108KS4 Spore coat protein MY9_3101 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) MY9_3103 ENOG4105CNB Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) MY9_3106 ENOG4105N67 Proton-coupled thiamine transporter YuaJ MY9_3107 ENOG4105VRR gCN5-related N-acetyltransferase MY9_3108 ENOG4105DZ6 Band 7 protein MY9_3110 ENOG4106DF1 MY9_3111 ENOG4108VNY MOSC domain protein MY9_3112 ENOG4108JB8 alcohol dehydrogenase MY9_3113 ENOG4105C26 Dehydrogenase MY9_3114 ENOG4105TRT Transcriptional regulator MY9_3117 ENOG4105CZN Potassium uptake protein MY9_3118 ENOG4107I77 yiaA/B two helix domain MY9_3119 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj MY9_3123 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) MY9_3125 ENOG4105EE0 oxidoreductase MY9_3126 ENOG4105DKG l-rhamnose isomerase MY9_3127 ENOG4105M10 Involved in the anomeric conversion of L-rhamnose (By similarity) MY9_3128 ENOG4105DET Rhamnulokinase MY9_3129 ENOG4105E98 transcriptional regulator DeoR family MY9_3131 ENOG4105C8Q Methyl-accepting chemotaxis MY9_3132 ENOG4105C8Q Methyl-accepting chemotaxis MY9_3133 ENOG4105C8Q Methyl-accepting chemotaxis MY9_3134 ENOG4105C8Q Methyl-accepting chemotaxis MY9_3137 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme MY9_3139 ENOG4105C37 (CBS) domain MY9_3142 ENOG4107PBV potassium channel MY9_3143 ENOG4107PBV potassium channel MY9_3146 ENOG4107QYV phosphohexose isomerase MY9_3148 ENOG4107QW4 alcohol dehydrogenase MY9_3149 ENOG4105WG9 Conserved Protein MY9_3151 ENOG4105CHM Aminotransferase MY9_3152 ENOG4108ZB6 transcriptional regulator AsnC family MY9_3153 ENOG4108MUZ hydrolase MY9_3155 ENOG4105C87 Aminotransferase class I and II MY9_3156 ENOG4108HGU Histidine kinase MY9_3157 ENOG4105Y38 Kinase-associated protein B MY9_3161 ENOG4105BZ4 penicillin-binding protein MY9_3162 ENOG4105KIR Thiol-disulfide oxidoreductase dcc MY9_3165 ENOG4108MRH transcriptional regulatory protein MY9_3166 ENOG4105DIH basic membrane MY9_3167 ENOG4108JQ9 ABC transporter MY9_3168 ENOG4105UIB (ABC) transporter MY9_3172 ENOG4105D65 subunit l MY9_3173 ENOG4105HC0 Na H antiporter MY9_3174 ENOG4108ZE9 Monovalent cation H antiporter subunit C MY9_3175 ENOG4108JPZ Monovalent cation H antiporter subunit D MY9_3176 ENOG4105SC1 monovalent cation H antiporter subunit E MY9_3178 ENOG4105KJM monovalent cation h antiporter subunit g MY9_3179 ENOG4105KA0 thioesterase Superfamily protein MY9_3181 ENOG4105BZU Histidine kinase MY9_3186 ENOG4105D58 Diguanylate phosphodiesterase MY9_3187 ENOG4105DAP Nicotinate phosphoribosyltransferase MY9_3192 ENOG4105C02 permease MY9_3198 ENOG410904N short-chain dehydrogenase reductase MY9_3204 ENOG4108K8K Transcriptional regulator MY9_3205 ENOG4105DCF alanine dehydrogenase MY9_3207 ENOG4105WQT MbtH domain protein MY9_3208 ENOG4105CEY Amp-dependent synthetase and ligase MY9_3209 ENOG4105WQI isochorismatase MY9_3210 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase MY9_3211 ENOG4105E4F Isochorismate synthase MY9_3212 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase MY9_3213 ENOG4105NIV Esterase MY9_3216 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) MY9_3218 ENOG41069ER domain protein MY9_3221 ENOG4105CEP NADH dehydrogenase MY9_3223 ENOG4105CAY ferredoxin--nadp reductase MY9_3228 ENOG41090PH Protease synthase and sporulation negative regulatory protein pai 1 MY9_3229 ENOG4108YX9 iron--sulfur cluster insertion protein erpA MY9_3232 ENOG4105ZKE UPF0349 protein MY9_3235 ENOG41083MR nifu domain-containing protein MY9_3236 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein MY9_3237 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) MY9_3238 ENOG4108IYI Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity) MY9_3239 ENOG4105D6E homoserine dehydrogenase MY9_3241 ENOG4108W5N phosphatidylglycerophosphatase a MY9_3242 ENOG4105D4U had-superfamily hydrolase, subfamily iia MY9_3244 ENOG4105MMD transcriptional regulator MY9_3245 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) MY9_3246 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) MY9_3247 ENOG4105FAA peptidase M23 MY9_3248 ENOG4108YTE sporulation protein YunB MY9_3249 ENOG4105KZD Domain of unknown function (DUF1805) MY9_3250 ENOG4107R8B 5'-nucleotidase MY9_3252 ENOG4105I3N Conserved Protein MY9_3254 ENOG4105CD3 dihydroorotase MY9_3255 ENOG4105G9B Transcriptional regulator MY9_3258 ENOG4105FFA Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin (By similarity) MY9_3259 ENOG4105VT2 5-hydroxyisourate hydrolase MY9_3280 ENOG4107YV9 domain protein MY9_3281 ENOG4105CE2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding MY9_3284 ENOG4105XRQ Xanthine dehydrogenase accessory factor MY9_3286 ENOG4105C5R Aminotransferase MY9_3289 ENOG4108K8S endonuclease I MY9_3290 ENOG4108IJ9 (ABC) transporter MY9_3291 ENOG4105FDP GntR family transcriptional regulator MY9_3292 ENOG4108KPW sugar kinase MY9_3293 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component MY9_3294 ENOG4105F0P binding-protein-dependent transport systems inner membrane Component MY9_3295 ENOG4105XN3 extracellular solute-binding protein family 1 MY9_3296 ENOG4107R1S catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine MY9_3297 ENOG4105PKS Excinuclease abc c subunit domain protein MY9_3299 ENOG4107VFR oxidoreductase MY9_3302 ENOG4105DIW FeS assembly protein SUFB MY9_3303 ENOG4108UNV SUF system FeS assembly protein, NifU family MY9_3304 ENOG4105C9B Cysteine desulfurase MY9_3305 ENOG4105JRK feS assembly protein SufD MY9_3306 ENOG4105C3K feS assembly ATPase SufC MY9_3311 ENOG4105D01 (LipO)protein MY9_3312 ENOG4108UMI ABC transporter, permease MY9_3313 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) MY9_3318 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) MY9_3319 ENOG41080E8 Transcriptional regulator, Spx MgsR family MY9_3320 ENOG4105C1G acyl-Coa dehydrogenase MY9_3321 ENOG4105CHU acetyl-coa acetyltransferase MY9_3327 ENOG41067TZ transcriptional regulator, MarR family MY9_3328 ENOG4105C0R drug resistance transporter emrb qaca subfamily MY9_3329 ENOG4105MDS 4-oxalocrotonate tautomerase MY9_3331 ENOG4105EGI Transcriptional regulator MY9_3333 ENOG4105E0A ABC, transporter MY9_3336 ENOG4105E1F short-chain dehydrogenase reductase MY9_3337 ENOG4105HUF DNA protection during starvation protein MY9_3338 ENOG4105C0H protease MY9_3340 ENOG4105F3H Histidine kinase MY9_3342 ENOG41067SE Tetr family transcriptional regulator MY9_3343 ENOG4105C9Q fumarate hydratase class II MY9_3348 ENOG4105WH1 Two component transcriptional regulator luxr family MY9_3349 ENOG4105ENE Histidine kinase MY9_3352 ENOG41087YS Phage shock protein A MY9_3356 ENOG4108WBT adenosyltransferase MY9_3357 ENOG4105E0A ABC, transporter MY9_3358 ENOG4105EHG Permease protein MY9_3359 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) MY9_3361 ENOG4105EWI Short-chain dehydrogenase reductase Sdr MY9_3362 ENOG4105CYF SMP-30 gluconolaconase LRE domain protein MY9_3364 ENOG4105DPZ Two component transcriptional regulator (Winged helix family MY9_3367 ENOG4106DF4 Sigma-70, region 4 MY9_3369 ENOG4105F0F Oxalate decarboxylase MY9_3371 ENOG4107RBB ABC transporter, permease MY9_3372 ENOG4105C19 ABC transporter MY9_3373 ENOG4108WMK Efflux transporter RND family MFP subunit MY9_3374 ENOG4105E0A ABC, transporter MY9_3375 ENOG4105EHG Permease protein MY9_3376 ENOG4105DQ5 transport system permease protein MY9_3379 ENOG4105D5Q Arginine ornithine antiporter MY9_3381 ENOG4107K5X Membrane-bound metal-dependent hydrolase MY9_3382 ENOG4107QZ2 Sulfatase MY9_3383 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family MY9_3384 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein MY9_3385 ENOG4105E0C molybdate abc transporter MY9_3388 ENOG4105EEQ Na H antiporter MY9_3389 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) MY9_3390 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) MY9_3391 ENOG4105EEM helicase MY9_3393 ENOG4105EN6 Membrane MY9_3395 ENOG4107ZQN disulfide bond MY9_3396 ENOG4105C59 p-type ATPase MY9_3398 ENOG4105C59 p-type ATPase MY9_3399 ENOG410681U heavy metal transport detoxification protein MY9_3400 ENOG4105VPX protein, conserved in bacteria MY9_3401 ENOG4105D9R oxidoreductase MY9_3402 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) MY9_3404 ENOG4105RXJ MY9_3405 ENOG4105KPY Small multidrug resistance protein MY9_3406 ENOG4105KBX Transcriptional regulator, TetR family MY9_3407 ENOG4105EWI Short-chain dehydrogenase reductase Sdr MY9_3408 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) MY9_3409 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) MY9_3411 ENOG4105XZU Preprotein translocase, subunit SecG MY9_3416 ENOG4105KVH Transcriptional regulator MY9_3417 ENOG4105C8Q Methyl-accepting chemotaxis MY9_3418 ENOG4105R40 Glycine betaine carnitine choline MY9_3419 ENOG4108HQR Glycine betaine MY9_3420 ENOG4105E90 ABC transporter MY9_3421 ENOG4108IJ8 ABC transporter MY9_3422 ENOG4107HG4 Transcriptional regulator MY9_3423 ENOG4105R40 Glycine betaine carnitine choline MY9_3424 ENOG4108HQR Glycine betaine MY9_3425 ENOG4105E90 ABC transporter MY9_3426 ENOG4108IJ8 ABC transporter MY9_3427 ENOG4107HG4 Transcriptional regulator MY9_3428 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein MY9_3429 ENOG4108QCI YvbH-like oligomerisation region MY9_3431 ENOG4105T65 Membrane-associated protein MY9_3432 ENOG4108W0I acetyltransferase MY9_3433 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) MY9_3434 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) MY9_3435 ENOG4105CP7 Triose-phosphate isomerase MY9_3436 ENOG4105BZA Phosphoglycerate kinase MY9_3439 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase MY9_3442 ENOG4105CMD Transcriptional regulator, GntR family MY9_3443 ENOG4105DEN Luciferase family MY9_3444 ENOG4105GZI Transcriptional regulator MY9_3445 ENOG4107RT3 EamA-like transporter family MY9_3447 ENOG4105VRS hydrolase family 18 MY9_3448 ENOG4108ZZK Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity) MY9_3449 ENOG4107QR9 Iron-sulfur cluster binding protein MY9_3450 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) MY9_3452 ENOG4105BZU Histidine kinase MY9_3453 ENOG4105KCT ABC transporter MY9_3454 ENOG4108M15 ABC transporter MY9_3455 ENOG4107R6F Alpha Beta Hydrolase Fold protein MY9_3456 ENOG4108MJI response regulator MY9_3459 ENOG4105EG2 ABC transporter, permease MY9_3461 ENOG4107FKK extracellular solute-binding protein family 1 MY9_3463 ENOG4105JXH GntR family transcriptional regulator MY9_3464 ENOG4105DAA L-lactate MY9_3465 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) MY9_3468 ENOG4108ZPC Polysaccharide pyruvyl transferase MY9_3469 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase MY9_3470 ENOG4105MME Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family MY9_3471 ENOG4105D3Q Sugar transferase MY9_3473 ENOG4105K64 Glycosyl transferase, family 2 MY9_3475 ENOG4107QRS glycosyltransferase group 2 family protein MY9_3476 ENOG41068W6 Capsular polysaccharide biosynthesis protein MY9_3477 ENOG4108KMV Glycosyl transferase (Group 1 MY9_3478 ENOG4105K64 Glycosyl transferase, family 2 MY9_3479 ENOG4108PQP glycosyl transferase group 1 MY9_3481 ENOG4105HTX biosynthesis protein MY9_3483 ENOG4105EBR Carboxylesterase MY9_3485 ENOG4105PY6 Phenolic acid decarboxylase MY9_3486 ENOG4105NI3 Protein of unknown function (DUF3237) MY9_3488 ENOG4105FQP Beta-lactamase MY9_3489 ENOG4105EDQ levansucrase EC 2.4.1.10 MY9_3490 ENOG4108HKT sucrose-6-phosphate hydrolase MY9_3491 ENOG4107QTZ amino acid MY9_3497 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) MY9_3498 ENOG4107URF beta-phospho-glucomutase MY9_3499 ENOG4105CG3 alpha amylase, catalytic region MY9_3501 ENOG4105EG2 ABC transporter, permease MY9_3502 ENOG4105D56 permease protein MY9_3503 ENOG4107FKK extracellular solute-binding protein family 1 MY9_3504 ENOG4108IUK alpha amylase, catalytic MY9_3505 ENOG4105FKQ transcriptional regulator MY9_3506 ENOG4108URH decarboxylase MY9_3507 ENOG4105TPC MazG nucleotide pyrophosphohydrolase domain MY9_3508 ENOG4105CHH sulfate transporter MY9_3509 ENOG4108V2W Carbonate dehydratase MY9_3510 ENOG4105C5I Dehydrogenase MY9_3512 ENOG4105C19 ABC transporter MY9_3513 ENOG4105EWM Histidine kinase MY9_3515 ENOG4107A6P MY9_3516 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase MY9_3517 ENOG4105KRI phosphocarrier protein (HPr MY9_3518 ENOG4105CIE May be required for sporulation (By similarity) MY9_3519 ENOG4105CHW UPF0052 protein MY9_3520 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) MY9_3521 ENOG4108Z4K mutator MutT protein MY9_3522 ENOG4105C3M thioredoxin reductase MY9_3525 ENOG4105BZ1 (ABC) transporter MY9_3527 ENOG4106FGC MY9_3531 ENOG4106FGC MY9_3534 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase MY9_3535 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) MY9_3536 ENOG4105CJV Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase MY9_3537 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) MY9_3538 ENOG4105ECC imidazole-glycerol-phosphate dehydratase MY9_3539 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) MY9_3540 ENOG4107RN8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) MY9_3541 ENOG4105C49 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity) MY9_3544 ENOG4108E16 pectate lyase MY9_3545 ENOG4108S4C acetyltransferase MY9_3546 ENOG4107XGZ Hydrolase MY9_3547 ENOG4105HKU nucleoside recognition domain-containing protein MY9_3548 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) MY9_3549 ENOG4105D1C Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity) MY9_3550 ENOG4105CE4 GlcNAc 6-P deacetylase MY9_3551 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) MY9_3552 ENOG4105FDP GntR family transcriptional regulator MY9_3553 ENOG41088CQ domain protein MY9_3554 ENOG41086DT Membrane protein of unknown function MY9_3555 ENOG41067S9 phage shock protein C, PspC MY9_3556 ENOG4108PY7 MY9_3559 ENOG4105I03 Flagellin MY9_3560 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) MY9_3561 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) MY9_3565 ENOG4105MKU Transcriptional regulator MY9_3570 ENOG4105CN1 protease MY9_3571 ENOG4105CRP Part of the ABC transporter FtsEX involved in MY9_3572 ENOG4105CAK Cell division ATP-binding protein ftsE MY9_3575 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) MY9_3576 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) MY9_3578 ENOG4105MS2 ribosomal subunit Interface protein MY9_3582 ENOG4105MQ3 flagellar protein FliS MY9_3583 ENOG4107RT6 flagellar hook-associated MY9_3584 ENOG41083S7 flagellar protein FlaG MY9_3585 ENOG4105I03 Flagellin MY9_3586 ENOG41085Y9 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) MY9_3587 ENOG4105W5T Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity) MY9_3588 ENOG4105MKD MY9_3589 ENOG4105DTJ flagellar hook-associated protein MY9_3590 ENOG4105E1Q flagellar hook-associated protein MY9_3593 ENOG4105RU3 MY9_3594 ENOG41081UC Inherit from COG: Competence protein MY9_3598 ENOG4105WH1 Two component transcriptional regulator luxr family MY9_3599 ENOG4105BZU Histidine kinase MY9_3600 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein MY9_3601 ENOG4108KGH TRANSCRIPTIONal MY9_3602 ENOG4105ESV Glycosyl transferase, family 4 MY9_3603 ENOG4107EF8 Glycosyl transferase (Group 1 MY9_3606 ENOG4105QZI O-Antigen Polymerase MY9_3607 ENOG4105C6Y Udp-glucose 6-dehydrogenase MY9_3608 ENOG4107RA4 Glycosyl transferase (Group 1 MY9_3609 ENOG4105PSV Polysaccharide Biosynthesis Protein MY9_3610 ENOG4105D3Q Sugar transferase MY9_3612 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase MY9_3613 ENOG4105JFG SpoIID LytB domain protein MY9_3616 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase MY9_3620 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase MY9_3621 ENOG4105EY8 ABC transporter MY9_3623 ENOG4105CPK Glycosyl transferase (Group 1 MY9_3624 ENOG4107VDP teichoic acid biosynthesis MY9_3635 ENOG4105DG6 mannose-6-phosphate isomerase MY9_3639 ENOG4108NHD germination protein MY9_3640 ENOG4105C54 Major Facilitator superfamily MY9_3641 ENOG4108KGH TRANSCRIPTIONal MY9_3642 ENOG4105J7I hydrolase MY9_3643 ENOG4105K4H Nlp p60 protein MY9_3645 ENOG4105PNM synthesis protein MY9_3647 ENOG4105N98 Capsule biosynthesis protein capB MY9_3649 ENOG4105ETE Transcriptional regulator (LacI family MY9_3650 ENOG4108RVA ribokinase MY9_3651 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) MY9_3652 ENOG4105C2J ABC transporter MY9_3653 ENOG4105CNN ABC, transporter MY9_3654 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator MY9_3658 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein MY9_3659 ENOG4107FQX Alpha-acetolactate decarboxylase MY9_3661 ENOG4107RSM transcriptional regulator MY9_3664 ENOG4106UIA MY9_3667 ENOG4107XC4 flavin reductase domain protein, FMN-binding MY9_3669 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) MY9_3671 ENOG4105CAH Chromate MY9_3672 ENOG4105FGV Chromate MY9_3674 ENOG4108WS4 fmn reductase MY9_3675 ENOG4107V2S Transcriptional regulator MY9_3676 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) MY9_3687 ENOG4108XI2 Domain of unknown function (DUF1963) MY9_3688 ENOG4105C6Y Udp-glucose 6-dehydrogenase MY9_3689 ENOG4108RB3 Capsular polysaccharide biosynthesis protein MY9_3690 ENOG4107YJ4 chain length determinant protein MY9_3691 ENOG4105HTX biosynthesis protein MY9_3693 ENOG4105KBK Zinc finger, swim domain protein MY9_3694 ENOG4105C0D helicase MY9_3695 ENOG410667J hydrolase MY9_3696 ENOG4105E98 transcriptional regulator DeoR family MY9_3697 ENOG4105Z8H single-stranded DNA-binding protein MY9_3702 ENOG4108VAC response regulator MY9_3704 ENOG4105M2E Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity) MY9_3705 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) MY9_3707 ENOG4105CGA flagellar basal-body rod protein FlgG MY9_3709 ENOG4105DFF Rod shape-determining protein mreb MY9_3710 ENOG4105MT0 Sporulation transcriptional regulator spoiiid MY9_3711 ENOG4107MII Sugar-specific transcriptional regulator TrmB MY9_3712 ENOG4105CZM Major Facilitator MY9_3714 ENOG4108M26 parallel beta-helix repeat protein MY9_3715 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease MY9_3717 ENOG41080V3 Major Facilitator superfamily MY9_3718 ENOG4105D3W isochorismatase MY9_3719 ENOG4107P26 MY9_3720 ENOG4105BZU Histidine kinase MY9_3722 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase MY9_3724 ENOG4105FRN stage II sporulation protein MY9_3725 ENOG4107TCE N-acetyltransferase MY9_3730 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) MY9_3731 ENOG4107TXC Transcriptional regulator MY9_3732 ENOG4106BRK MY9_3733 ENOG4108RYK Nad-dependent epimerase dehydratase MY9_3734 ENOG4108Z40 Transcriptional regulator MY9_3735 ENOG4105CQM Urea amidohydrolase subunit alpha MY9_3736 ENOG4105KI2 Urea amidohydrolase subunit beta MY9_3737 ENOG4108YZ9 Urea amidohydrolase subunit gamma MY9_3738 ENOG4108IV0 ABC, transporter MY9_3739 ENOG4105C0Z ABC transporter MY9_3741 ENOG4105C32 Amino acid ABC transporter (Permease) MY9_3742 ENOG4107TSX ABC branched chain amino acid family transporter periplasmic ligand binding protein MY9_3750 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) MY9_3753 ENOG4108TF4 von Willebrand factor, type A MY9_3755 ENOG4105JFG SpoIID LytB domain protein MY9_3757 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) MY9_3759 ENOG4106778 Protein of unknown function (DUF1146) MY9_3761 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) MY9_3762 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) MY9_3763 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) MY9_3764 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) MY9_3768 ENOG4107RB6 it plays a direct role in the translocation of protons across the membrane (By similarity) MY9_3770 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) MY9_3771 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) MY9_3772 ENOG4108UIC UPF0340 protein MY9_3773 ENOG4108YZG isomerase MY9_3775 ENOG4107WAU Protein tyrosine phosphatase MY9_3776 ENOG410815N Probably functions as a manganese efflux pump (By similarity) MY9_3777 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) MY9_3779 ENOG4108ZXQ stage ii sporulation protein r MY9_3782 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) MY9_3783 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) MY9_3784 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase MY9_3786 ENOG4107TT2 Auxin Efflux Carrier MY9_3787 ENOG4105C6K Malic enzyme MY9_3788 ENOG4107104 thymidine kinase MY9_3789 ENOG41082DI 50s ribosomal protein l31 MY9_3790 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) MY9_3792 ENOG4105CBT Fructose-1,6-bisphosphatase MY9_3793 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) MY9_3794 ENOG4107XMI Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway MY9_3795 ENOG4105D2N Aldolase MY9_3796 ENOG410812K response regulator receiver protein MY9_3798 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) MY9_3801 ENOG4105C1G acyl-Coa dehydrogenase MY9_3802 ENOG4105DF6 Fe-S oxidoreductase MY9_3804 ENOG4105E5J UV damage endonuclease MY9_3806 ENOG4105NAE bifunctional deaminase-reductase domain protein MY9_3807 ENOG4105BZ1 (ABC) transporter MY9_3808 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) MY9_3811 ENOG4105R3A Nitrate reductase MY9_3812 ENOG4108IUE nitrate reductase beta subunit MY9_3817 ENOG4107V6Q Cyclic nucleotide-binding domain MY9_3819 ENOG4105C75 arginyL-tRNA synthetase MY9_3820 ENOG410684U Domain of unknown function (DUF1934) MY9_3822 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E MY9_3832 ENOG4107JM4 Tetratricopeptide repeat MY9_3834 ENOG4108UIN ybak prolyl-trna synthetase associated region MY9_3835 ENOG4105CYW agmatinase MY9_3836 ENOG4105CCX Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) MY9_3837 ENOG4105BZ4 penicillin-binding protein MY9_3838 ENOG4108XFG YwhD family MY9_3839 ENOG4108Z4T Peptidase M50 MY9_3840 ENOG41069HH 4-oxalocrotonate tautomerase MY9_3841 ENOG41067TZ transcriptional regulator, MarR family MY9_3842 ENOG4105C22 threonyL-tRNA synthetase MY9_3845 ENOG4105C57 major facilitator superfamily MY9_3846 ENOG41062ES Transcriptional regulator MY9_3848 ENOG4105DCI Phosphohydrolase MY9_3850 ENOG4108VCI transcription factor, rsfa family MY9_3852 ENOG4108RNG Permease of the drug metabolite transporter MY9_3854 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) MY9_3855 ENOG4105DUM transcriptional regulator, lysR family MY9_3856 ENOG4108IJ2 phosphate acetyltransferase MY9_3860 ENOG4105CHM Aminotransferase MY9_3862 ENOG4108V3M Inherit from COG: acetyl-CoA carboxylase biotin carboxylase MY9_3863 ENOG4105CHR reductase MY9_3864 ENOG4106CHD Bacilysin biosynthesis protein bacB MY9_3866 ENOG41061WN bacilysin biosynthesis protein MY9_3867 ENOG4105FCW Major Facilitator superfamily MY9_3870 ENOG4105C26 Dehydrogenase MY9_3871 ENOG4105D82 Glutamate dehydrogenase MY9_3874 ENOG4107ZIM Dtdp-4-dehydrorhamnose 3,5-epimerase MY9_3875 ENOG4105C1B dTDP-glucose 4-6-dehydratase MY9_3876 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) MY9_3877 ENOG4107P9E Inherit from COG: pseudaminic acid biosynthesis-associated protein PseG MY9_3878 ENOG4107TY6 Acylneuraminate cytidylyltransferase MY9_3880 ENOG41067MN Spore coat polysaccharide biosynthesis protein spsD MY9_3881 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase MY9_3891 ENOG4105C26 Dehydrogenase MY9_3892 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) MY9_3893 ENOG4108RJ9 Glycosyl transferase, family 2 MY9_3894 ENOG4105DWF phosphomethylpyrimidine kinase MY9_3897 ENOG4105C5Y PTS System MY9_3898 ENOG4108QTI )-transporter MY9_3902 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin MY9_3903 ENOG4105DEN Luciferase family MY9_3904 ENOG4108DBC nitroreductase MY9_3907 ENOG41060D1 Quinol oxidase MY9_3908 ENOG4105CCU oxidase (Subunit III) MY9_3909 ENOG4105BZ9 Cytochrome C oxidase, subunit I MY9_3910 ENOG4105E2S oxidase) subunit II MY9_3912 ENOG4107BMA Transglycosylase associated protein MY9_3914 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) MY9_3915 ENOG4105WH5 Teichoic acid glycosylation protein MY9_3920 ENOG4107ZXU DSBA oxidoreductase MY9_3921 ENOG4105DBE peroxidase MY9_3922 ENOG410650H (LipO)protein MY9_3923 ENOG4107SJW iron permease, FTR1 MY9_3924 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) MY9_3926 ENOG4105CMU LysR family (Transcriptional regulator MY9_3927 ENOG4105VAW lrga family MY9_3928 ENOG41067MG lrgb family MY9_3929 ENOG4108RDQ ABC transporter MY9_3934 ENOG41067MG lrgb family MY9_3935 ENOG4105D8G Major Facilitator superfamily MY9_3938 ENOG4105DR4 Methyltransferase MY9_3941 ENOG4108YV3 Protein of unknown function (DUF2711) MY9_3942 ENOG4105CK1 PTS System MY9_3944 ENOG4105J8Z peptidase S8 and S53, subtilisin, kexin, sedolisin MY9_3948 ENOG4105X1N Glycosyl transferase family 8 MY9_3950 ENOG4105GVJ transcriptional regulator MY9_3951 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) MY9_3952 ENOG4105IIU Aminopeptidase MY9_3958 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase MY9_3962 ENOG4108IQD Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity) MY9_3963 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein MY9_3965 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD MY9_3966 ENOG4108VHC Short-chain dehydrogenase reductase Sdr MY9_3967 ENOG4105CM2 brancheD-chain amino acid aminotransferase MY9_3968 ENOG4105F8D glycoside hydrolase family 4 MY9_3969 ENOG4105VCP PTS System MY9_3970 ENOG4105CK1 PTS System MY9_3971 ENOG4105VZJ PTS System MY9_3972 ENOG4105EMD TRANSCRIPTIONal MY9_3975 ENOG4108VX5 3-methyladenine DNA glycosylase MY9_3976 ENOG4105CH6 catalase MY9_3979 ENOG4105DA5 (ABC) transporter MY9_3980 ENOG41069JR MY9_3985 ENOG4105ETS cytosine purines uracil thiamine allantoin MY9_3986 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) MY9_3987 ENOG4108JJ8 (ABC) transporter MY9_3988 ENOG4108JJ9 ABC, transporter MY9_3989 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii MY9_3990 ENOG4105C4M (Ubiquinol oxidase) subunit I MY9_3991 ENOG4105D2K citrate carrier protein MY9_3995 ENOG4107BJW polysaccharide deacetylase MY9_4000 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) MY9_4002 ENOG4105CMR udp-glucose 4-epimerase MY9_4005 ENOG4105BZU Histidine kinase MY9_4006 ENOG4105WH1 Two component transcriptional regulator luxr family MY9_4007 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) MY9_4013 ENOG4105DTD Dehydrogenase MY9_4014 ENOG4108IIH CoA-transferase subunit B MY9_4015 ENOG4105D6N CoA-transferase, subunit a MY9_4016 ENOG4105CY2 Citrate transporter MY9_4018 ENOG4105DHI Methyltransferase MY9_4023 ENOG4105CH6 catalase MY9_4024 ENOG4105D4T Citrate transporter MY9_4025 ENOG4108RZ2 Glycoside hydrolase family 16 MY9_4027 ENOG4105CID antiterminator MY9_4030 ENOG4105DEU major facilitator superfamily MY9_4031 ENOG4105C1J atp-dependent rna helicase MY9_4032 ENOG4107TDE lipolytic protein G-D-S-L family MY9_4044 ENOG4107EXU Short-chain dehydrogenase reductase Sdr MY9_4046 ENOG4107YZX Universal stress protein MY9_4047 ENOG4105CS2 ec 3.2.1.21 MY9_4048 ENOG4105C5Y PTS System MY9_4056 ENOG4107EV6 Inherit from COG: YD repeat protein MY9_4059 ENOG4106Z5D Glycoside Hydrolase Family 43 MY9_4062 ENOG4105C84 Histidine ammonia-lyase MY9_4063 ENOG4105CGP Urocanate hydratase MY9_4064 ENOG4105CI2 imidazolone-5-propionate hydrolase MY9_4065 ENOG4107W25 arginase agmatinase formiminoglutamase MY9_4067 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) MY9_4068 ENOG4105D9N nucleoside MY9_4071 ENOG4107RHR regulatoR MY9_4073 ENOG4108TM9 integral membrane protein MY9_4074 ENOG4105ENY Ethanolamine utilization protein eutH MY9_4075 ENOG4108PGP mmge prpd family protein MY9_4076 ENOG4105CH2 amidohydrolase MY9_4078 ENOG4108HW4 amino acid AbC transporter MY9_4079 ENOG4105EAB amino acid AbC transporter MY9_4080 ENOG4108XSB acetyltransferase, (GNAT) family MY9_4081 ENOG4105CPU Monooxygenase MY9_4083 ENOG4107QHE Choloylglycine hydrolase MY9_4085 ENOG410667J hydrolase MY9_4092 ENOG4108V5C ABC transporter MY9_4098 ENOG4105D2N Aldolase MY9_4099 ENOG4107TRN Xylose isomerase domain protein TIM barrel MY9_4100 ENOG4105F0H myo-inositol catabolism protein MY9_4101 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) MY9_4103 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) MY9_4104 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) MY9_4105 ENOG4105D7K pfkb domain protein MY9_4107 ENOG4105C26 Dehydrogenase MY9_4109 ENOG4105CPC Aldo Keto reductase MY9_4116 ENOG4107QNK )-transporter MY9_4117 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) MY9_4119 ENOG41061TZ Short-chain dehydrogenase reductase Sdr MY9_4121 ENOG4105ST3 Transcriptional regulator MY9_4122 ENOG4105C26 Dehydrogenase MY9_4123 ENOG41085PJ rdd domain containing protein MY9_4124 ENOG4108ITS PQQ enzyme repeat MY9_4126 ENOG41085PJ rdd domain containing protein MY9_4129 ENOG4105J7D transcriptional regulator MY9_4130 ENOG4107JEE Short-chain dehydrogenase reductase Sdr MY9_4131 ENOG41061AU MarR family Transcriptional regulator MY9_4133 ENOG41067MG lrgb family MY9_4140 ENOG4105BZW Glycerate kinase MY9_4141 ENOG4105G3Z GntR family transcriptional regulator MY9_4142 ENOG4105CMG Carbohydrate kinase MY9_4143 ENOG4105C6Z Gluconate MY9_4144 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) MY9_4145 ENOG4105D3R alkyl hydroperoxide reductase MY9_4146 ENOG4108JU3 Alkyl hydroperoxide reductase MY9_4150 ENOG4105DMC D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3 MY9_4153 ENOG4105DZR Type I site-specific deoxyribonuclease MY9_4156 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) MY9_4159 ENOG4105E2A Dehydrogenase MY9_4163 ENOG4105NUN Orthopoxvirus protein of unknown function (DUF830) MY9_4164 ENOG4105WQG acetyltransferase MY9_4165 ENOG410780I phosphoprotein phosphatase activity MY9_4167 ENOG41066UZ arginase EC 3.5.3.1 MY9_4168 ENOG4108IQI permease MY9_4169 ENOG4105C8Y Acetylornithine aminotransferase MY9_4170 ENOG4108JUB Transcriptional regulator MY9_4171 ENOG4105BZU Histidine kinase MY9_4175 ENOG4105C0H protease MY9_4176 ENOG4105Q2H domain protein MY9_4179 ENOG4105BZU Histidine kinase MY9_4180 ENOG4105CK6 Two component transcriptional regulator (Winged helix family MY9_4181 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis MY9_4182 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase MY9_4183 ENOG4105CDU Replicative dna helicase MY9_4187 ENOG4105DJ2 Major Facilitator Superfamily MY9_4190 ENOG4105EDW glycosyl transferase, family 39 MY9_4191 ENOG4105K9Q Binds to the 23S rRNA (By similarity) MY9_4192 ENOG4105BZR domain protein MY9_4193 ENOG4108XMW Membrane MY9_4196 ENOG4105KVH Transcriptional regulator MY9_4197 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase MY9_4204 ENOG4105VN1 Heat shock protein MY9_4207 ENOG4108VSZ Inherit from COG: ketosteroid isomerase-like protein MY9_4208 ENOG4105DDN Pentapeptide repeat-containing protein MY9_4209 ENOG4105D94 Major Facilitator Superfamily MY9_4210 ENOG4107RSM transcriptional regulator MY9_4211 ENOG41082BV acetyltransferase MY9_4212 ENOG41081I9 integral membrane protein MY9_4214 ENOG4108U05 Transcriptional regulator MY9_4215 ENOG41082BV acetyltransferase MY9_4217 ENOG4108U7W acetyltransferase MY9_4218 ENOG4105UNS Pfam:DUF419 MY9_4219 ENOG4105NAE bifunctional deaminase-reductase domain protein MY9_4221 ENOG4108IPJ Membrane MY9_4222 ENOG4105C7Z Conserved Protein MY9_4223 ENOG4107FCW Abortive infection protein MY9_4225 ENOG4108UW5 maltose o-acetyltransferase MY9_4226 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase MY9_4229 ENOG4105CGK Exodeoxyribonuclease III MY9_4230 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) MY9_4231 ENOG4108UUM single-stranded DNA-binding protein MY9_4232 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) MY9_4233 ENOG4105C3G gtp-binding protein MY9_4234 ENOG4108J2R molybdopterin oxidoreductase MY9_4235 ENOG4105VDK protein, conserved in bacteria MY9_4238 ENOG4108ZDA Sporulation protein YyaC MY9_4239 ENOG4105FA0 parb-like partition protein MY9_4240 ENOG4107QJE Chromosome Partitioning Protein MY9_4243 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) MY9_4244 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity) MY9_4245 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) MY9_4248 ENOG4105M7T RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)