locus-tag	class	description
FFE90_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFE90_000010	COG0592	DNA-directed DNA polymerase activity
FFE90_000015	COG2501	S4 domain
FFE90_000020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FFE90_000030	COG0187	DNA topoisomerase II activity
FFE90_000035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFE90_000070	COG0517	IMP dehydrogenase activity
FFE90_000070	COG0516	GMP reductase activity
FFE90_000075	COG1686	Belongs to the peptidase S11 family
FFE90_000080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FFE90_000085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FFE90_000090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFE90_000100	COG1428	Deoxynucleoside kinase
FFE90_000105	COG1428	Deoxynucleoside kinase
FFE90_000110	COG3858	chitin binding
FFE90_000110	COG1388	LysM domain
FFE90_000115	COG1335	isochorismatase
FFE90_000120	COG0590	tRNA wobble adenosine to inosine editing
FFE90_000130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FFE90_000135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FFE90_000140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FFE90_000185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FFE90_000190	COG3853	Toxic anion resistance protein (TelA)
FFE90_000195	COG1982	Orn Lys Arg decarboxylase major
FFE90_000200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFE90_000205	COG3870	Protein conserved in bacteria
FFE90_000210	COG1728	Protein conserved in bacteria
FFE90_000215	COG0470	DNA polymerase III
FFE90_000220	COG1774	PSP1 C-terminal conserved region
FFE90_000225	COG4467	Involved in initiation control of chromosome replication
FFE90_000230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FFE90_000235	COG2827	Endonuclease containing a URI domain
FFE90_000240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FFE90_000245	COG2002	toxin-antitoxin pair type II binding
FFE90_000250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE90_000250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE90_000255	COG0084	hydrolase, TatD family'
FFE90_000260	COG3584	3D domain protein
FFE90_000260	COG3583	domain protein
FFE90_000265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FFE90_000270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFE90_000280	COG4466	Protein conserved in bacteria
FFE90_000290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FFE90_000295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFE90_000300	COG0251	oxidation-reduction process
FFE90_000305	COG2088	sporulation resulting in formation of a cellular spore
FFE90_000310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FFE90_000315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FFE90_000320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FFE90_000325	COG0193	aminoacyl-tRNA hydrolase activity
FFE90_000335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FFE90_000340	COG2002	toxin-antitoxin pair type II binding
FFE90_000345	COG2244	polysaccharide biosynthetic process
FFE90_000350	COG3956	TIGRFAM MazG family protein
FFE90_000355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FFE90_000370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FFE90_000375	COG1098	S1 RNA binding domain
FFE90_000390	COG2208	phosphoserine phosphatase activity
FFE90_000395	COG2304	oxidoreductase activity
FFE90_000400	COG0515	serine threonine protein kinase
FFE90_000405	COG0037	tRNA processing
FFE90_000415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFE90_000420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FFE90_000425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FFE90_000430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFE90_000435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FFE90_000440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FFE90_000445	COG0512	Glutamine amidotransferase of anthranilate synthase
FFE90_000450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE90_000455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FFE90_000460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FFE90_000465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FFE90_000470	COG1396	sequence-specific DNA binding
FFE90_000475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE90_000480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FFE90_000560	COG4463	regulation of RNA biosynthetic process
FFE90_000565	COG3880	PFAM UvrB UvrC protein
FFE90_000570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FFE90_000575	COG0542	response to heat
FFE90_000580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FFE90_000585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FFE90_000590	COG4956	integral membrane protein (PIN domain superfamily)
FFE90_000595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FFE90_000600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FFE90_000605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFE90_000615	COG1045	serine acetyltransferase
FFE90_000620	COG0215	cysteine-tRNA ligase activity
FFE90_000625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FFE90_000630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE90_000635	COG3688	RNA-binding protein containing a PIN domain
FFE90_000640	COG1595	DNA-templated transcription, initiation
FFE90_000645	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFE90_000650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFE90_000655	COG0250	Participates in transcription elongation, termination and antitermination
FFE90_000660	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FFE90_000665	COG0081	regulation of translation
FFE90_000670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FFE90_000675	COG0222	ribosome binding
FFE90_000680	COG2813	Specifically methylates the guanine in position
FFE90_000685	COG0085	RNA polymerase activity
FFE90_000690	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FFE90_000695	COG1358	cellular component organization or biogenesis
FFE90_000700	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FFE90_000705	COG0049	tRNA binding
FFE90_000710	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFE90_000715	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFE90_000720	COG0596	Alpha beta hydrolase
FFE90_000725	COG0051	transcription antitermination factor activity, RNA binding
FFE90_000730	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FFE90_000735	COG0088	Forms part of the polypeptide exit tunnel
FFE90_000740	COG0089	rRNA binding
FFE90_000745	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FFE90_000750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FFE90_000755	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FFE90_000760	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FFE90_000765	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FFE90_000770	COG0255	Belongs to the universal ribosomal protein uL29 family
FFE90_000775	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FFE90_000780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FFE90_000790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FFE90_000800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FFE90_000805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FFE90_000810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FFE90_000815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FFE90_000820	COG1841	ribosomal large subunit assembly
FFE90_000825	COG0200	Binds to the 23S rRNA
FFE90_000830	COG0201	protein transport
FFE90_000835	COG0563	adenylate kinase activity
FFE90_000840	COG0024	Methionine aminopeptidase
FFE90_000845	COG2163	COG2163 Ribosomal protein L14E L6E L27E
FFE90_000850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FFE90_000855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFE90_000860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FFE90_000865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FFE90_000870	COG0202	RNA polymerase activity
FFE90_000875	COG0203	ribosomal protein L17
FFE90_000880	COG1122	ATPase activity
FFE90_000885	COG1122	ATPase activity
FFE90_000890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FFE90_000895	COG0101	tRNA pseudouridine synthase activity
FFE90_000900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FFE90_000905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FFE90_000910	COG2226	methyltransferase
FFE90_000920	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE90_000925	COG0489	protein tyrosine kinase activity
FFE90_000935	COG2194	sulfuric ester hydrolase activity
FFE90_000940	COG0726	polysaccharide deacetylase
FFE90_001025	COG0659	secondary active sulfate transmembrane transporter activity
FFE90_001030	COG0385	Bile acid
FFE90_001035	COG2819	hydrolase of the alpha beta superfamily
FFE90_001040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_001045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_001050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE90_001055	COG2207	Transcriptional regulator
FFE90_001055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE90_001060	COG3876	Protein conserved in bacteria
FFE90_001065	COG1472	Belongs to the glycosyl hydrolase 3 family
FFE90_001070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FFE90_001075	COG1263	PTS System
FFE90_001075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_001080	COG1737	Transcriptional regulator
FFE90_001085	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FFE90_001090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_001095	COG1683	Conserved Protein
FFE90_001125	COG1595	DNA-templated transcription, initiation
FFE90_001130	COG5662	AntiSigma factor
FFE90_001135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FFE90_001140	COG4856	YbbR-like protein
FFE90_001145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFE90_001150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFE90_001160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FFE90_001165	COG2169	Transcriptional regulator
FFE90_001170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFE90_001175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFE90_001180	COG3002	Belongs to the UPF0753 family
FFE90_001185	COG0288	reversible hydration of carbon dioxide
FFE90_001195	COG5609	conserved protein (DUF2294)
FFE90_001200	COG0640	Transcriptional regulator
FFE90_001205	COG2814	Major facilitator Superfamily
FFE90_001210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFE90_001220	COG0535	radical SAM domain protein
FFE90_001225	COG1266	CAAX protease self-immunity
FFE90_001230	COG1131	(ABC) transporter
FFE90_001240	COG1413	lyase activity
FFE90_001245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_001250	COG0596	Alpha beta hydrolase
FFE90_001255	COG0745	RESPONSE REGULATOR receiver
FFE90_001260	COG0642	Histidine kinase
FFE90_001270	COG0515	serine threonine protein kinase
FFE90_001285	COG1113	amino acid transport
FFE90_001300	COG2602	Beta-lactamase
FFE90_001305	COG2124	cytochrome p450
FFE90_001315	COG0531	amino acid
FFE90_001320	COG0584	glycerophosphoryl diester phosphodiesterase
FFE90_001325	COG2271	Major facilitator Superfamily
FFE90_001340	COG0456	acetyltransferase
FFE90_001340	COG1846	Transcriptional regulator
FFE90_001345	COG2271	Major facilitator Superfamily
FFE90_001360	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_001365	COG0697	spore germination
FFE90_001370	COG2207	Transcriptional regulator
FFE90_001370	COG1917	Cupin 2, conserved barrel domain protein
FFE90_001375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FFE90_001380	COG3591	Belongs to the peptidase S1B family
FFE90_001390	COG0596	Alpha beta hydrolase
FFE90_001395	COG1183	phosphatidylcholine synthase activity
FFE90_001400	COG0586	Pfam SNARE associated Golgi protein
FFE90_001405	COG0688	phosphatidylethanolamine metabolic process
FFE90_001415	COG2312	Erythromycin esterase
FFE90_001420	COG2207	Transcriptional regulator
FFE90_001430	COG1301	dicarboxylic acid transport
FFE90_001435	COG2190	(PTS) system
FFE90_001435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_001435	COG1263	PTS System
FFE90_001440	COG0363	glucosamine-6-phosphate deaminase activity
FFE90_001455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE90_001460	COG0833	amino acid
FFE90_001465	COG2040	homocysteine
FFE90_001475	COG1115	amino acid carrier protein
FFE90_001480	COG2066	Belongs to the glutaminase family
FFE90_001485	COG4191	Histidine kinase
FFE90_001490	COG0784	Response regulator, receiver
FFE90_001500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFE90_001505	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_001510	COG2271	Major facilitator Superfamily
FFE90_001515	COG4948	Mandelate Racemase Muconate Lactonizing
FFE90_001520	COG2186	Transcriptional regulator
FFE90_001525	COG2721	sulfolactate sulfo-lyase activity
FFE90_001530	COG3173	Aminoglycoside phosphotransferase
FFE90_001540	COG0697	spore germination
FFE90_001545	COG0745	RESPONSE REGULATOR receiver
FFE90_001550	COG2205	protein histidine kinase activity
FFE90_001555	COG1131	(ABC) transporter
FFE90_001575	COG3773	Cell wall hydrolase
FFE90_001580	COG2304	oxidoreductase activity
FFE90_001590	COG3540	Alkaline phosphatase
FFE90_001595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE90_001600	COG0805	protein transport
FFE90_001605	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FFE90_001610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FFE90_001615	COG0477	Major facilitator Superfamily
FFE90_001620	COG1309	transcriptional regulator
FFE90_001625	COG0252	asparaginase activity
FFE90_001630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FFE90_001635	COG1714	RDD family
FFE90_001640	COG1405	negative regulation of cell septum assembly
FFE90_001640	COG3012	SEC-C Motif Domain Protein
FFE90_001645	COG3290	protein histidine kinase activity
FFE90_001650	COG3279	Response regulator of the LytR AlgR family
FFE90_001655	COG4555	ABC transporter
FFE90_001660	COG1668	transmembrane transport
FFE90_001665	COG0667	Aldo Keto reductase
FFE90_001680	COG1595	DNA-templated transcription, initiation
FFE90_001685	COG1595	DNA-templated transcription, initiation
FFE90_001690	COG1876	peptidase activity
FFE90_001695	COG0457	Tetratricopeptide repeat
FFE90_001700	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_001705	COG0366	Alpha amylase catalytic
FFE90_001710	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFE90_001715	COG1121	(ABC) transporter
FFE90_001720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE90_001725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE90_001735	COG2310	stress, protein
FFE90_001740	COG2310	stress, protein
FFE90_001745	COG0861	Integral membrane protein TerC family
FFE90_001755	COG3853	Toxic anion resistance protein (TelA)
FFE90_001760	COG0477	Major facilitator Superfamily
FFE90_001770	COG2814	Major facilitator Superfamily
FFE90_001775	COG0640	Transcriptional regulator
FFE90_001780	COG4175	Glycine betaine
FFE90_001780	COG0517	IMP dehydrogenase activity
FFE90_001785	COG4176	ABC-type proline glycine betaine transport system permease component
FFE90_001790	COG2113	Glycine betaine
FFE90_001795	COG1473	amidohydrolase
FFE90_001800	COG1288	antiporter activity
FFE90_001810	COG0366	Alpha amylase catalytic
FFE90_001815	COG0039	L-malate dehydrogenase activity
FFE90_001820	COG1620	l-lactate permease
FFE90_001825	COG2814	Major facilitator Superfamily
FFE90_001830	COG1846	Transcriptional regulator
FFE90_001835	COG1280	lysine exporter protein (LysE YggA)
FFE90_001840	COG3403	YqcI/YcgG family
FFE90_001845	COG1113	amino acid transport
FFE90_001850	COG3665	Urea carboxylase-associated protein
FFE90_001855	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FFE90_001860	COG1660	Displays ATPase and GTPase activities
FFE90_001870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFE90_001875	COG2226	methyltransferase
FFE90_001880	COG0583	DNA-binding transcription factor activity
FFE90_001885	COG3458	cephalosporin-C deacetylase activity
FFE90_001890	COG3541	Predicted nucleotidyltransferase
FFE90_001895	COG0506	proline dehydrogenase activity
FFE90_001900	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_001905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE90_001910	COG2508	Transcriptional regulator
FFE90_001915	COG3689	TIGRFAM TIGR03943 family protein
FFE90_001920	COG0701	Predicted permease
FFE90_001925	COG2267	carboxylic ester hydrolase activity
FFE90_001930	COG0492	ferredoxin-NADP+ reductase activity
FFE90_001935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE90_001935	COG1587	Uroporphyrinogen-III synthase
FFE90_001940	COG2146	nitrite reductase [NAD(P)H] activity
FFE90_001945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFE90_001950	COG0243	molybdopterin cofactor binding
FFE90_001955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFE90_001960	COG2223	nitrite transmembrane transporter activity
FFE90_001965	COG1469	GTP cyclohydrolase I activity
FFE90_001970	COG1376	ErfK ybiS ycfS ynhG family protein
FFE90_001980	COG0523	cobalamin synthesis protein
FFE90_001985	COG0765	amino acid transport
FFE90_001990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE90_002000	COG1714	RDD family
FFE90_002010	COG2723	6-phospho-beta-galactosidase activity
FFE90_002020	COG3209	COG3209 Rhs family protein
FFE90_002025	COG0840	transmembrane signaling receptor activity
FFE90_002025	COG3290	protein histidine kinase activity
FFE90_002030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FFE90_002035	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FFE90_002040	COG1733	regulation of RNA biosynthetic process
FFE90_002045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_002050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_002055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_002060	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FFE90_002065	COG2814	Major facilitator Superfamily
FFE90_002075	COG0697	spore germination
FFE90_002080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE90_002090	COG2364	Membrane
FFE90_002095	COG1126	abc transporter atp-binding protein
FFE90_002100	COG0765	amino acid transport
FFE90_002105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE90_002110	COG0583	DNA-binding transcription factor activity
FFE90_002115	COG0163	prenyltransferase activity
FFE90_002120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FFE90_002135	COG0596	Alpha beta hydrolase
FFE90_002140	COG3104	oligopeptide transport
FFE90_002145	COG5434	Belongs to the glycosyl hydrolase 28 family
FFE90_002155	COG0697	spore germination
FFE90_002165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FFE90_002170	COG1136	(ABC) transporter
FFE90_002175	COG0577	efflux transmembrane transporter activity
FFE90_002180	COG0745	RESPONSE REGULATOR receiver
FFE90_002185	COG3850	Histidine kinase
FFE90_002185	COG5002	protein histidine kinase activity
FFE90_002190	COG0457	Tetratricopeptide repeat
FFE90_002210	COG0527	aspartate kinase activity
FFE90_002215	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_002220	COG4605	iron ion homeostasis
FFE90_002225	COG4604	ABC transporter, ATP-binding protein
FFE90_002230	COG4607	ABC-type enterochelin transport system periplasmic component
FFE90_002235	COG2814	Major facilitator Superfamily
FFE90_002240	COG1309	transcriptional regulator
FFE90_002245	COG0778	Nitroreductase
FFE90_002250	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FFE90_002255	COG0640	Transcriptional regulator
FFE90_002260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE90_002265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FFE90_002270	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_002275	COG4975	Glucose uptake
FFE90_002280	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_002285	COG4549	nuclear export factor GLE1
FFE90_002290	COG1276	copper resistance
FFE90_002290	COG2372	response to copper ion
FFE90_002295	COG1349	DNA-binding transcription factor activity
FFE90_002305	COG2213	PTS system mannitol-specific
FFE90_002310	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_002315	COG0246	Mannitol dehydrogenase
FFE90_002320	COG0473	3-isopropylmalate dehydrogenase activity
FFE90_002325	COG0681	Belongs to the peptidase S26 family
FFE90_002330	COG0412	Dienelactone hydrolase
FFE90_002335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFE90_002345	COG0561	phosphatase activity
FFE90_002350	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FFE90_002355	COG1914	H( )-stimulated, divalent metal cation uptake system
FFE90_002360	COG4336	lyase activity
FFE90_002365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FFE90_002370	COG1984	allophanate hydrolase subunit 2
FFE90_002375	COG1414	Transcriptional regulator
FFE90_002380	COG2755	lipolytic protein G-D-S-L family
FFE90_002390	COG2329	Antibiotic biosynthesis monooxygenase
FFE90_002395	COG0768	penicillin binding
FFE90_002400	COG4989	oxidoreductase activity
FFE90_002405	COG3711	transcriptional antiterminator
FFE90_002410	COG0318	PFAM AMP-dependent synthetase and ligase
FFE90_002415	COG2226	methyltransferase
FFE90_002420	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_002425	COG1917	Cupin 2, conserved barrel domain protein
FFE90_002430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_002435	COG3871	stress protein (general stress protein 26)
FFE90_002445	COG2814	Major facilitator Superfamily
FFE90_002450	COG1522	sequence-specific DNA binding
FFE90_002455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFE90_002455	COG0551	DNA topoisomerase type I activity
FFE90_002460	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FFE90_002465	COG3706	GGDEF domain
FFE90_002470	COG5298	Protein conserved in bacteria
FFE90_002475	COG1215	transferase activity, transferring glycosyl groups
FFE90_002485	COG0531	amino acid
FFE90_002490	COG0494	nUDIX hydrolase
FFE90_002495	COG0028	Belongs to the TPP enzyme family
FFE90_002510	COG1914	H( )-stimulated, divalent metal cation uptake system
FFE90_002515	COG2261	transglycosylase associated protein
FFE90_002520	COG4876	unkown
FFE90_002525	COG2217	Heavy metal translocating P-type atpase
FFE90_002530	COG3729	General stress protein
FFE90_002535	COG0662	Cupin 2, conserved barrel domain protein
FFE90_002540	COG2329	Antibiotic biosynthesis monooxygenase
FFE90_002545	COG3546	catalase activity
FFE90_002550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FFE90_002555	COG3290	protein histidine kinase activity
FFE90_002560	COG4565	transcriptional regulatory protein
FFE90_002565	COG1301	dicarboxylic acid transport
FFE90_002570	COG0628	permease
FFE90_002575	COG1131	(ABC) transporter
FFE90_002580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FFE90_002590	COG1960	acyl-CoA dehydrogenase activity
FFE90_002605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FFE90_002610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_002615	COG1181	Belongs to the D-alanine--D-alanine ligase family
FFE90_002620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FFE90_002630	COG0513	Belongs to the DEAD box helicase family
FFE90_002635	COG3402	PFAM membrane-flanked domain
FFE90_002640	COG3428	Bacterial PH domain
FFE90_002650	COG0705	Rhomboid family
FFE90_002655	COG0736	holo-[acyl-carrier-protein] synthase activity
FFE90_002660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FFE90_002665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFE90_002670	COG0864	Transcriptional regulator
FFE90_002675	COG2337	Toxic component of a toxin-antitoxin (TA) module
FFE90_002680	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_002685	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_002690	COG2172	sigma factor antagonist activity
FFE90_002695	COG2208	phosphoserine phosphatase activity
FFE90_002700	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_002705	COG2172	sigma factor antagonist activity
FFE90_002710	COG1191	sigma factor activity
FFE90_002715	COG2208	phosphoserine phosphatase activity
FFE90_002730	COG1673	EVE domain
FFE90_002735	COG1846	Transcriptional regulator
FFE90_002740	COG2183	response to ionizing radiation
FFE90_002750	COG3091	SprT-like family
FFE90_002790	COG0582	viral genome integration into host DNA
FFE90_002795	COG2856	Zn peptidase
FFE90_002800	COG1396	sequence-specific DNA binding
FFE90_002830	COG1674	ftsk spoiiie
FFE90_002835	COG2946	Replication initiation factor
FFE90_002870	COG0433	COG0433 Predicted ATPase
FFE90_002880	COG5644	endopeptidase inhibitor activity
FFE90_002885	COG0791	NLP P60 protein
FFE90_002885	COG0741	lytic transglycosylase activity
FFE90_002905	COG0457	Tetratricopeptide repeat
FFE90_002920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE90_002925	COG1522	sequence-specific DNA binding
FFE90_002930	COG1522	sequence-specific DNA binding
FFE90_002935	COG1335	isochorismatase
FFE90_002940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FFE90_002945	COG2814	Major facilitator Superfamily
FFE90_002965	COG0693	protein deglycase activity
FFE90_002970	COG1278	Cold shock
FFE90_002975	COG1329	Transcriptional regulator
FFE90_002990	COG1917	Cupin 2, conserved barrel domain protein
FFE90_002990	COG2207	Transcriptional regulator
FFE90_002995	COG0697	spore germination
FFE90_003000	COG3708	Transcriptional regulator
FFE90_003000	COG2207	Transcriptional regulator
FFE90_003005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE90_003010	COG0477	Major facilitator Superfamily
FFE90_003020	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FFE90_003030	COG0697	spore germination
FFE90_003035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE90_003040	COG2030	dehydratase
FFE90_003045	COG3545	Serine hydrolase
FFE90_003050	COG1733	regulation of RNA biosynthetic process
FFE90_003055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFE90_003060	COG1733	regulation of RNA biosynthetic process
FFE90_003065	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFE90_003070	COG2814	Major facilitator Superfamily
FFE90_003075	COG1309	transcriptional regulator
FFE90_003085	COG0640	Transcriptional regulator
FFE90_003090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FFE90_003100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_003105	COG0697	spore germination
FFE90_003110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE90_003115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FFE90_003120	COG0640	Transcriptional regulator
FFE90_003125	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE90_003140	COG4585	Histidine kinase
FFE90_003145	COG2197	response regulator
FFE90_003150	COG2409	Drug exporters of the RND superfamily
FFE90_003155	COG0596	Alpha beta hydrolase
FFE90_003160	COG1811	Na channel or pump
FFE90_003165	COG0789	Transcriptional regulator
FFE90_003165	COG4978	Transcriptional regulator
FFE90_003170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FFE90_003175	COG0778	Nitroreductase
FFE90_003180	COG0346	lactoylglutathione lyase activity
FFE90_003185	COG2259	Doxx family
FFE90_003190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_003205	COG2323	membrane
FFE90_003210	COG2323	membrane
FFE90_003215	COG0071	Belongs to the small heat shock protein (HSP20) family
FFE90_003230	COG1309	transcriptional regulator
FFE90_003240	COG0456	acetyltransferase
FFE90_003250	COG1113	amino acid transport
FFE90_003255	COG2318	DinB family
FFE90_003260	COG1846	Transcriptional regulator
FFE90_003265	COG1033	growth of symbiont in host cell
FFE90_003265	COG2409	Drug exporters of the RND superfamily
FFE90_003270	COG0778	Nitroreductase
FFE90_003275	COG1846	Transcriptional regulator
FFE90_003280	COG2814	Major facilitator Superfamily
FFE90_003285	COG0730	response to heat
FFE90_003290	COG1802	Transcriptional regulator
FFE90_003295	COG1388	LysM domain
FFE90_003295	COG3858	chitin binding
FFE90_003300	COG1819	glycosyl
FFE90_003310	COG1785	Belongs to the alkaline phosphatase family
FFE90_003315	COG5646	InterPro IPR014922
FFE90_003325	COG0454	-acetyltransferase
FFE90_003330	COG1078	dGTPase activity
FFE90_003335	COG1388	LysM domain
FFE90_003340	COG2814	Major facilitator Superfamily
FFE90_003345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE90_003350	COG1447	Phosphotransferase system cellobiose-specific component IIA
FFE90_003355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE90_003360	COG2723	6-phospho-beta-galactosidase activity
FFE90_003365	COG2188	Transcriptional regulator
FFE90_003370	COG1940	carbohydrate kinase activity
FFE90_003375	COG1482	cell wall glycoprotein biosynthetic process
FFE90_003380	COG4124	Belongs to the glycosyl hydrolase 26 family
FFE90_003425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FFE90_003430	COG0802	atpase or kinase
FFE90_003435	COG1214	PFAM Peptidase M22, glycoprotease
FFE90_003440	COG0456	acetyltransferase
FFE90_003445	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FFE90_003450	COG0488	(ABC) transporter
FFE90_003455	COG0315	cyclic pyranopterin monophosphate synthase activity
FFE90_003460	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FFE90_003465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE90_003470	COG0805	protein transport
FFE90_003480	COG1266	CAAX protease self-immunity
FFE90_003485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFE90_003490	COG0459	protein refolding
FFE90_003505	COG3378	Phage plasmid primase P4 family
FFE90_003520	COG0270	DNA (cytosine-5-)-methyltransferase activity
FFE90_003525	COG0270	DNA (cytosine-5-)-methyltransferase activity
FFE90_003545	COG1401	restriction endodeoxyribonuclease activity
FFE90_003570	COG1073	alpha beta
FFE90_003575	COG0457	Tetratricopeptide repeat
FFE90_003580	COG1063	alcohol dehydrogenase
FFE90_003585	COG2211	Major facilitator Superfamily
FFE90_003590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE90_003595	COG1842	Phage shock protein A
FFE90_003600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FFE90_003605	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FFE90_003610	COG4260	virion core protein, lumpy skin disease virus
FFE90_003620	COG2814	Major facilitator Superfamily
FFE90_003625	COG1063	alcohol dehydrogenase
FFE90_003630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFE90_003635	COG0823	Involved in the tonB-independent uptake of proteins
FFE90_003650	COG2267	carboxylic ester hydrolase activity
FFE90_003660	COG2132	Multicopper oxidase
FFE90_003665	COG1113	amino acid transport
FFE90_003675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FFE90_003680	COG0714	Associated with various cellular activities
FFE90_003685	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FFE90_003690	COG1305	Transglutaminase-like
FFE90_003695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FFE90_003695	COG0519	Catalyzes the synthesis of GMP from XMP
FFE90_003700	COG2252	PERMEase
FFE90_003705	COG3064	Membrane
FFE90_003715	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FFE90_003725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FFE90_003730	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FFE90_003735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFE90_003740	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FFE90_003745	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFE90_003750	COG0047	phosphoribosylformylglycinamidine synthase activity
FFE90_003755	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FFE90_003760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FFE90_003765	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FFE90_003770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FFE90_003775	COG0138	bifunctional purine biosynthesis protein purh
FFE90_003780	COG0151	Belongs to the GarS family
FFE90_003785	COG1522	sequence-specific DNA binding
FFE90_003790	COG0531	amino acid
FFE90_003800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FFE90_003805	COG1470	cell adhesion involved in biofilm formation
FFE90_003810	COG4496	protein, YerC YecD
FFE90_003815	COG0069	glutamate synthase activity
FFE90_003820	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FFE90_003825	COG0210	DNA helicase
FFE90_003830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFE90_003835	COG4851	CamS sex pheromone cAM373 precursor
FFE90_003840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFE90_003845	COG1285	pathogenesis
FFE90_003850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE90_003855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFE90_003860	COG0154	amidase activity
FFE90_003865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FFE90_003870	COG1309	transcriptional regulator
FFE90_003875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE90_003880	COG1597	lipid kinase activity
FFE90_003885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFE90_003890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE90_003895	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE90_003900	COG1002	Type II restriction enzyme, methylase subunits
FFE90_003905	COG1061	Type III restriction enzyme res subunit
FFE90_003910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FFE90_003930	COG5444	nuclease activity
FFE90_003935	COG3391	amine dehydrogenase activity
FFE90_003940	COG0457	Tetratricopeptide repeat
FFE90_003950	COG0217	transcriptional regulatory protein
FFE90_003960	COG1309	transcriptional regulator
FFE90_003965	COG3631	Ketosteroid isomerase-related protein
FFE90_003970	COG0702	epimerase
FFE90_003985	COG3546	catalase activity
FFE90_003990	COG0454	-acetyltransferase
FFE90_004000	COG5578	integral membrane protein
FFE90_004005	COG2972	Histidine kinase
FFE90_004010	COG4753	response regulator
FFE90_004010	COG2207	Transcriptional regulator
FFE90_004015	COG1653	transport
FFE90_004020	COG1175	transmembrane transport
FFE90_004025	COG0395	ABC-type sugar transport system, permease component
FFE90_004030	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FFE90_004035	COG2207	Transcriptional regulator
FFE90_004040	COG2755	lipolytic protein G-D-S-L family
FFE90_004050	COG5578	integral membrane protein
FFE90_004055	COG3401	FG-GAP repeat protein
FFE90_004060	COG3401	FG-GAP repeat protein
FFE90_004065	COG2755	lipolytic protein G-D-S-L family
FFE90_004070	COG1874	Beta-galactosidase
FFE90_004080	COG1653	transport
FFE90_004085	COG4209	transmembrane transport
FFE90_004090	COG0395	ABC-type sugar transport system, permease component
FFE90_004095	COG1486	melibiose metabolic process
FFE90_004100	COG2323	membrane
FFE90_004105	COG2329	Antibiotic biosynthesis monooxygenase
FFE90_004110	COG0346	lactoylglutathione lyase activity
FFE90_004125	COG5583	Uncharacterized small protein (DUF2292)
FFE90_004130	COG0670	Belongs to the BI1 family
FFE90_004135	COG0697	spore germination
FFE90_004140	COG1846	Transcriptional regulator
FFE90_004145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE90_004155	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FFE90_004155	COG2124	cytochrome p450
FFE90_004160	COG1368	sulfuric ester hydrolase activity
FFE90_004165	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FFE90_004170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE90_004175	COG1442	glycosyl transferase family 8
FFE90_004180	COG1216	Glycosyl transferase, family 2
FFE90_004185	COG1442	glycosyl transferase family 8
FFE90_004190	COG2223	nitrite transmembrane transporter activity
FFE90_004195	COG1011	Hydrolase
FFE90_004200	COG0531	amino acid
FFE90_004205	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_004210	COG0840	transmembrane signaling receptor activity
FFE90_004215	COG0488	(ABC) transporter
FFE90_004225	COG0789	Transcriptional regulator
FFE90_004230	COG2814	Major facilitator Superfamily
FFE90_004245	COG0488	(ABC) transporter
FFE90_004250	COG0513	Belongs to the DEAD box helicase family
FFE90_004255	COG0456	acetyltransferase
FFE90_004260	COG2130	NADP-dependent
FFE90_004270	COG2211	Major facilitator Superfamily
FFE90_004275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FFE90_004280	COG1120	ATPase activity
FFE90_004285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_004290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_004295	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FFE90_004310	COG3866	Pectate lyase
FFE90_004315	COG0471	metal ion transport
FFE90_004320	COG3290	protein histidine kinase activity
FFE90_004325	COG4565	transcriptional regulatory protein
FFE90_004330	COG3181	Tripartite tricarboxylate transporter family receptor
FFE90_004335	COG2851	Citrate transporter
FFE90_004340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_004345	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FFE90_004350	COG1254	Belongs to the acylphosphatase family
FFE90_004355	COG2258	MOSC domain
FFE90_004375	COG0024	Methionine aminopeptidase
FFE90_004380	COG1263	PTS System
FFE90_004380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_004385	COG1368	sulfuric ester hydrolase activity
FFE90_004400	COG1115	amino acid carrier protein
FFE90_004405	COG0531	amino acid
FFE90_004420	COG0697	spore germination
FFE90_004425	COG1263	PTS System
FFE90_004425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_004430	COG0366	Alpha amylase catalytic
FFE90_004435	COG2188	Transcriptional regulator
FFE90_004440	COG0778	Nitroreductase
FFE90_004445	COG0737	Belongs to the 5'-nucleotidase family
FFE90_004450	COG0693	protein deglycase activity
FFE90_004455	COG2814	Major facilitator Superfamily
FFE90_004460	COG4840	Belongs to the UPF0435 family
FFE90_004465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFE90_004470	COG4980	gas vesicle protein
FFE90_004475	COG1295	ribonuclease BN
FFE90_004480	COG0477	Major facilitator Superfamily
FFE90_004485	COG0387	Pfam Sodium calcium exchanger
FFE90_004495	COG0668	transmembrane transport
FFE90_004500	COG0535	radical SAM domain protein
FFE90_004510	COG0726	polysaccharide deacetylase
FFE90_004515	COG2084	Dehydrogenase
FFE90_004520	COG0598	Magnesium transport protein CorA
FFE90_004525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FFE90_004530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFE90_004540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE90_004545	COG4637	Psort location Cytoplasmic, score
FFE90_004555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FFE90_004560	COG0022	dehydrogenase e1 component
FFE90_004565	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE90_004570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE90_004575	COG3284	Transcriptional regulator
FFE90_004585	COG1742	UPF0060 membrane protein
FFE90_004610	COG4842	Belongs to the WXG100 family
FFE90_004615	COG1486	melibiose metabolic process
FFE90_004620	COG1737	Transcriptional regulator
FFE90_004625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_004625	COG1263	PTS System
FFE90_004630	COG1132	(ABC) transporter
FFE90_004635	COG1132	(ABC) transporter
FFE90_004640	COG2259	Doxx family
FFE90_004645	COG2514	catechol 2,3-dioxygenase activity
FFE90_004650	COG4977	sequence-specific DNA binding
FFE90_004650	COG1917	Cupin 2, conserved barrel domain protein
FFE90_004655	COG2814	Major facilitator Superfamily
FFE90_004660	COG1082	Xylose isomerase domain protein TIM barrel
FFE90_004665	COG0673	inositol 2-dehydrogenase activity
FFE90_004670	COG4585	Histidine kinase
FFE90_004675	COG2197	response regulator
FFE90_004680	COG1131	(ABC) transporter
FFE90_004685	COG1511	domain protein
FFE90_004685	COG0842	Transport permease protein
FFE90_004690	COG0842	Transport permease protein
FFE90_004695	COG1695	Transcriptional regulator
FFE90_004700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FFE90_004705	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FFE90_004710	COG1309	transcriptional regulator
FFE90_004715	COG2814	Major facilitator Superfamily
FFE90_004720	COG2318	DinB family
FFE90_004725	COG2814	Major facilitator Superfamily
FFE90_004730	COG1846	Transcriptional regulator
FFE90_004735	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FFE90_004735	COG0392	lysyltransferase activity
FFE90_004740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE90_004745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_004750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_004755	COG0384	phenazine biosynthesis protein PhzF
FFE90_004760	COG0778	Nitroreductase
FFE90_004775	COG1090	epimerase
FFE90_004780	COG2137	regulation of response to DNA damage stimulus
FFE90_004790	COG2814	Major facilitator Superfamily
FFE90_004805	COG3103	Sh3 type 3 domain protein
FFE90_004810	COG5658	integral membrane protein
FFE90_004815	COG0596	Alpha beta hydrolase
FFE90_004820	COG0463	Glycosyl transferase, family 2
FFE90_004825	COG4485	Bacterial membrane protein, YfhO
FFE90_004830	COG1988	membrane-bound metal-dependent
FFE90_004835	COG1194	a g-specific adenine glycosylase
FFE90_004845	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_004860	COG3557	Belongs to the UPF0374 family
FFE90_004865	COG1132	(ABC) transporter
FFE90_004870	COG4129	membrane
FFE90_004875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFE90_004880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FFE90_004885	COG0735	belongs to the Fur family
FFE90_004995	COG4326	sporulation control protein
FFE90_005005	COG5577	PFAM Coat F domain
FFE90_005010	COG3340	Belongs to the peptidase S51 family
FFE90_005015	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FFE90_005020	COG0277	FAD linked oxidase domain protein
FFE90_005030	COG0753	catalase activity
FFE90_005035	COG1116	anion transmembrane transporter activity
FFE90_005040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFE90_005045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFE90_005050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE90_005060	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFE90_005070	COG1476	TRANSCRIPTIONal
FFE90_005080	COG3382	B3 4 domain protein
FFE90_005085	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FFE90_005095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FFE90_005100	COG0789	Transcriptional regulator
FFE90_005105	COG1664	Polymer-forming cytoskeletal
FFE90_005110	COG1664	Polymer-forming cytoskeletal
FFE90_005115	COG2766	serine protein kinase
FFE90_005120	COG2718	Belongs to the UPF0229 family
FFE90_005125	COG1846	Transcriptional regulator
FFE90_005130	COG1566	PFAM secretion protein HlyD family protein
FFE90_005135	COG2814	Major facilitator Superfamily
FFE90_005140	COG0655	NAD(P)H dehydrogenase (quinone) activity
FFE90_005160	COG1725	Transcriptional regulator
FFE90_005165	COG1131	(ABC) transporter
FFE90_005170	COG1131	(ABC) transporter
FFE90_005175	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FFE90_005180	COG1278	Cold shock
FFE90_005190	COG1464	Belongs to the NlpA lipoprotein family
FFE90_005195	COG3706	GGDEF domain
FFE90_005200	COG1823	symporter activity
FFE90_005220	COG5577	PFAM Coat F domain
FFE90_005225	COG0737	Belongs to the 5'-nucleotidase family
FFE90_005225	COG1525	nuclease
FFE90_005225	COG4085	toxin activity
FFE90_005230	COG3764	Sortase (surface protein transpeptidase)
FFE90_005235	COG0564	pseudouridine synthase activity
FFE90_005245	COG0517	IMP dehydrogenase activity
FFE90_005250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE90_005255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE90_005255	COG3153	acetyltransferase
FFE90_005260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFE90_005265	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FFE90_005270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFE90_005275	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE90_005280	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FFE90_005285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FFE90_005290	COG4585	Histidine kinase
FFE90_005290	COG2203	Gaf domain
FFE90_005295	COG2197	response regulator
FFE90_005300	COG0431	NADPH-dependent FMN reductase
FFE90_005315	COG0791	NLP P60 protein
FFE90_005315	COG1388	LysM domain
FFE90_005320	COG1959	2 iron, 2 sulfur cluster binding
FFE90_005325	COG0668	transmembrane transport
FFE90_005330	COG2719	SpoVR family
FFE90_005335	COG1785	Belongs to the alkaline phosphatase family
FFE90_005340	COG0791	NLP P60 protein
FFE90_005340	COG1388	LysM domain
FFE90_005345	COG0583	DNA-binding transcription factor activity
FFE90_005350	COG0372	Belongs to the citrate synthase family
FFE90_005355	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_005360	COG0531	amino acid
FFE90_005365	COG0733	neurotransmitter:sodium symporter activity
FFE90_005370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE90_005375	COG0456	acetyltransferase
FFE90_005390	COG1595	DNA-templated transcription, initiation
FFE90_005395	COG0667	Aldo Keto reductase
FFE90_005400	COG0204	Acyl-transferase
FFE90_005405	COG1253	flavin adenine dinucleotide binding
FFE90_005410	COG0789	Transcriptional regulator
FFE90_005415	COG0436	Aminotransferase
FFE90_005420	COG1253	flavin adenine dinucleotide binding
FFE90_005425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFE90_005430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFE90_005435	COG0584	glycerophosphoryl diester phosphodiesterase
FFE90_005445	COG0668	transmembrane transport
FFE90_005450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FFE90_005455	COG0726	polysaccharide deacetylase
FFE90_005460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE90_005465	COG1757	Na H antiporter
FFE90_005470	COG0589	response to stress
FFE90_005480	COG1132	(ABC) transporter
FFE90_005485	COG1132	(ABC) transporter
FFE90_005490	COG0702	epimerase
FFE90_005510	COG0189	ligase activity
FFE90_005515	COG0189	ligase activity
FFE90_005520	COG4399	Belongs to the UPF0754 family
FFE90_005525	COG3679	Belongs to the UPF0342 family
FFE90_005530	COG4335	DNA alkylation repair
FFE90_005535	COG0561	phosphatase activity
FFE90_005540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE90_005545	COG0475	glutathione-regulated potassium exporter activity
FFE90_005550	COG0490	domain, Protein
FFE90_005560	COG1024	Enoyl-CoA hydratase
FFE90_005570	COG4152	abc transporter atp-binding protein
FFE90_005575	COG1668	transmembrane transport
FFE90_005580	COG0420	3'-5' exonuclease activity
FFE90_005585	COG4717	serine-type aminopeptidase activity
FFE90_005590	COG3481	metal-dependent phosphohydrolase, HD sub domain
FFE90_005600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFE90_005630	COG1846	Transcriptional regulator
FFE90_005635	COG4980	gas vesicle protein
FFE90_005650	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FFE90_005655	COG0537	adenosine 5'-monophosphoramidase activity
FFE90_005660	COG1131	(ABC) transporter
FFE90_005665	COG4473	ABC transporter
FFE90_005675	COG1473	amidohydrolase
FFE90_005680	COG3069	C4-dicarboxylate transmembrane transporter activity
FFE90_005690	COG2329	Antibiotic biosynthesis monooxygenase
FFE90_005695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE90_005700	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FFE90_005715	COG1309	transcriptional regulator
FFE90_005720	COG1511	domain protein
FFE90_005725	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFE90_005730	COG4377	Putative membrane peptidase family (DUF2324)
FFE90_005740	COG1363	Peptidase, m42
FFE90_005745	COG4405	Protein conserved in bacteria
FFE90_005750	COG1301	dicarboxylic acid transport
FFE90_005760	COG1234	tRNA 3'-trailer cleavage
FFE90_005765	COG0095	Lipoate-protein ligase
FFE90_005770	COG0702	epimerase
FFE90_005775	COG0318	PFAM AMP-dependent synthetase and ligase
FFE90_005785	COG0501	Belongs to the peptidase M48B family
FFE90_005790	COG1404	Belongs to the peptidase S8 family
FFE90_005795	COG0456	acetyltransferase
FFE90_005800	COG0604	alcohol dehydrogenase
FFE90_005805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FFE90_005810	COG0406	alpha-ribazole phosphatase activity
FFE90_005815	COG0183	Belongs to the thiolase family
FFE90_005820	COG0318	PFAM AMP-dependent synthetase and ligase
FFE90_005825	COG1268	BioY protein
FFE90_005830	COG0840	transmembrane signaling receptor activity
FFE90_005835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFE90_005835	COG0723	plastoquinol--plastocyanin reductase activity
FFE90_005840	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_005850	COG4903	ComK protein
FFE90_005855	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_005865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE90_005880	COG0398	Pfam SNARE associated Golgi protein
FFE90_005885	COG0681	Belongs to the peptidase S26 family
FFE90_005890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE90_005895	COG1846	Transcriptional regulator
FFE90_005900	COG0738	Major facilitator superfamily
FFE90_005905	COG0673	inositol 2-dehydrogenase activity
FFE90_005910	COG0561	phosphatase activity
FFE90_005915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFE90_005920	COG1609	Transcriptional regulator
FFE90_005925	COG3180	Ammonia monooxygenase
FFE90_005930	COG2814	Major facilitator Superfamily
FFE90_005930	COG0477	Major facilitator Superfamily
FFE90_005935	COG4533	DNA binding
FFE90_005945	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FFE90_005950	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FFE90_005955	COG1074	ATP-dependent DNA helicase activity
FFE90_005960	COG0420	3'-5' exonuclease activity
FFE90_005965	COG0419	ATPase involved in DNA repair
FFE90_005970	COG1403	HNH endonuclease
FFE90_006010	COG5337	Spore coat protein CotH
FFE90_006015	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFE90_006025	COG1404	Belongs to the peptidase S8 family
FFE90_006035	COG0367	asparagine synthase
FFE90_006040	COG2318	DinB family
FFE90_006045	COG1562	ergosterol biosynthetic process
FFE90_006050	COG0534	Mate efflux family protein
FFE90_006055	COG2207	Transcriptional regulator
FFE90_006055	COG1917	Cupin 2, conserved barrel domain protein
FFE90_006060	COG1609	Transcriptional regulator
FFE90_006065	COG0673	inositol 2-dehydrogenase activity
FFE90_006070	COG2318	DinB family
FFE90_006075	COG1279	arginine transmembrane transporter activity
FFE90_006080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE90_006085	COG1357	PFAM Pentapeptide repeats (8 copies)
FFE90_006090	COG2267	carboxylic ester hydrolase activity
FFE90_006095	COG0529	Catalyzes the synthesis of activated sulfate
FFE90_006100	COG2046	Belongs to the sulfate adenylyltransferase family
FFE90_006105	COG0175	sulfate reduction
FFE90_006110	COG2045	Belongs to the ComB family
FFE90_006115	COG1809	phosphosulfolactate synthase activity
FFE90_006120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFE90_006125	COG4948	Mandelate Racemase Muconate Lactonizing
FFE90_006130	COG2814	Major facilitator Superfamily
FFE90_006135	COG0454	-acetyltransferase
FFE90_006140	COG2153	protein acetylation
FFE90_006145	COG0646	methionine synthase
FFE90_006145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FFE90_006150	COG1666	GTP binding
FFE90_006155	COG2996	Protein conserved in bacteria
FFE90_006175	COG1695	Transcriptional regulator
FFE90_006190	COG3227	Zinc metalloprotease (Elastase)
FFE90_006195	COG1307	EDD domain protein, DegV family
FFE90_006200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFE90_006215	COG0561	phosphatase activity
FFE90_006220	COG1073	alpha beta
FFE90_006225	COG2151	metal-sulfur cluster biosynthetic enzyme
FFE90_006235	COG0277	FAD linked oxidase domain protein
FFE90_006240	COG2271	Major facilitator Superfamily
FFE90_006245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FFE90_006260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFE90_006265	COG0505	Belongs to the CarA family
FFE90_006270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FFE90_006275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FFE90_006290	COG2267	carboxylic ester hydrolase activity
FFE90_006300	COG1744	ABC transporter substrate-binding protein PnrA-like
FFE90_006315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFE90_006320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE90_006325	COG5504	Zn-dependent protease
FFE90_006330	COG0444	Belongs to the ABC transporter superfamily
FFE90_006335	COG4608	Belongs to the ABC transporter superfamily
FFE90_006345	COG0601	transmembrane transport
FFE90_006350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE90_006360	COG0180	Tryptophanyl-tRNA synthetase
FFE90_006365	COG4166	transmembrane transport
FFE90_006370	COG0601	transmembrane transport
FFE90_006375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE90_006380	COG0444	Belongs to the ABC transporter superfamily
FFE90_006385	COG4608	Belongs to the ABC transporter superfamily
FFE90_006390	COG2814	Major facilitator Superfamily
FFE90_006395	COG0456	acetyltransferase
FFE90_006400	COG1393	Belongs to the ArsC family
FFE90_006405	COG0861	Integral membrane protein TerC family
FFE90_006415	COG4862	establishment of competence for transformation
FFE90_006425	COG4469	Competence protein
FFE90_006430	COG1164	Oligoendopeptidase f
FFE90_006450	COG2346	COG2346, Truncated hemoglobins
FFE90_006455	COG0741	lytic transglycosylase activity
FFE90_006460	COG4116	CYTH
FFE90_006470	COG2357	RelA SpoT domain protein
FFE90_006475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFE90_006480	COG0564	pseudouridine synthase activity
FFE90_006485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFE90_006490	COG0569	domain protein
FFE90_006490	COG0475	glutathione-regulated potassium exporter activity
FFE90_006495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FFE90_006500	COG0352	thiamine-phosphate diphosphorylase activity
FFE90_006505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFE90_006510	COG2104	thiamine diphosphate biosynthetic process
FFE90_006515	COG2022	thiamine diphosphate biosynthetic process
FFE90_006520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FFE90_006525	COG0351	phosphomethylpyrimidine kinase
FFE90_006530	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FFE90_006585	COG0210	DNA helicase
FFE90_006595	COG2153	protein acetylation
FFE90_006600	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FFE90_006605	COG2382	esterase
FFE90_006610	COG0626	cystathionine gamma-synthase activity
FFE90_006615	COG0626	cystathionine gamma-synthase activity
FFE90_006620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_006625	COG5505	Protein of unknown function (DUF819)
FFE90_006655	COG3677	Transposase
FFE90_006670	COG5484	DNA packaging
FFE90_006675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FFE90_006680	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_006690	COG3711	transcriptional antiterminator
FFE90_006690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_006695	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE90_006695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_006695	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE90_006700	COG1482	cell wall glycoprotein biosynthetic process
FFE90_006710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_006720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FFE90_006740	COG0109	protoheme IX farnesyltransferase activity
FFE90_006750	COG0726	polysaccharide deacetylase
FFE90_006765	COG5504	Zn-dependent protease
FFE90_006770	COG2205	protein histidine kinase activity
FFE90_006780	COG3383	formate dehydrogenase (NAD+) activity
FFE90_006785	COG2427	Protein of unknown function (DUF1641)
FFE90_006795	COG1051	belongs to the nudix hydrolase family
FFE90_006805	COG2124	cytochrome p450
FFE90_006810	COG1819	glycosyl
FFE90_006820	COG1587	Uroporphyrinogen-III synthase
FFE90_006825	COG0390	transport system, permease component
FFE90_006830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FFE90_006835	COG0697	spore germination
FFE90_006840	COG4297	protein containing double-stranded beta helix domain
FFE90_006850	COG1252	NADH dehydrogenase
FFE90_006855	COG1904	glucuronate isomerase
FFE90_006860	COG2211	Major facilitator Superfamily
FFE90_006865	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FFE90_006870	COG1063	alcohol dehydrogenase
FFE90_006875	COG1312	Catalyzes the dehydration of D-mannonate
FFE90_006880	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_006885	COG2271	Major facilitator Superfamily
FFE90_006890	COG1609	Transcriptional regulator
FFE90_006895	COG0246	Mannitol dehydrogenase
FFE90_006900	COG2721	sulfolactate sulfo-lyase activity
FFE90_006905	COG0730	response to heat
FFE90_006910	COG2318	DinB family
FFE90_006915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFE90_006920	COG0457	Tetratricopeptide repeat
FFE90_006930	COG2350	Protein conserved in bacteria
FFE90_006935	COG5632	N-Acetylmuramoyl-L-alanine amidase
FFE90_006935	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_006935	COG1388	LysM domain
FFE90_006945	COG4195	phage-related replication protein
FFE90_006950	COG3546	catalase activity
FFE90_006955	COG2856	Zn peptidase
FFE90_006960	COG1396	sequence-specific DNA binding
FFE90_006970	COG1522	sequence-specific DNA binding
FFE90_006975	COG1484	DNA-dependent DNA replication
FFE90_006995	COG1595	DNA-templated transcription, initiation
FFE90_007000	COG5484	DNA packaging
FFE90_007000	COG3728	DNA packaging
FFE90_007005	COG1783	phage Terminase large subunit
FFE90_007010	COG5518	Phage portal protein
FFE90_007015	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FFE90_007020	COG4653	Phage capsid family
FFE90_007070	COG5412	phage tail tape measure protein
FFE90_007070	COG3953	SLT domain
FFE90_007075	COG1652	LysM domain
FFE90_007080	COG4193	domain, Protein
FFE90_007090	COG3628	GPW Gp25 family protein
FFE90_007095	COG3299	homolog of phage Mu protein gp47
FFE90_007100	COG3778	Protein conserved in bacteria
FFE90_007140	COG5632	N-Acetylmuramoyl-L-alanine amidase
FFE90_007140	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_007160	COG0306	phosphate transporter
FFE90_007165	COG1392	Phosphate transport regulator
FFE90_007170	COG0531	amino acid
FFE90_007175	COG0346	lactoylglutathione lyase activity
FFE90_007185	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFE90_007190	COG0463	Glycosyl transferase, family 2
FFE90_007195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE90_007200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFE90_007205	COG2362	D-Aminopeptidase
FFE90_007210	COG0601	transmembrane transport
FFE90_007215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE90_007220	COG0444	Belongs to the ABC transporter superfamily
FFE90_007225	COG4166	transmembrane transport
FFE90_007230	COG1619	proteins homologs of microcin C7 resistance protein MccF
FFE90_007235	COG4948	Mandelate Racemase Muconate Lactonizing
FFE90_007240	COG0791	NLP P60 protein
FFE90_007245	COG4608	Belongs to the ABC transporter superfamily
FFE90_007250	COG2706	6-phosphogluconolactonase activity
FFE90_007255	COG1834	amidinotransferase
FFE90_007260	COG1607	acyl-coa hydrolase
FFE90_007265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE90_007265	COG1017	nitric oxide dioxygenase activity
FFE90_007275	COG2323	membrane
FFE90_007280	COG2318	DinB family
FFE90_007285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_007290	COG2076	Multidrug Resistance protein
FFE90_007295	COG2076	Multidrug Resistance protein
FFE90_007300	COG0788	formyltetrahydrofolate deformylase activity
FFE90_007305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FFE90_007310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FFE90_007315	COG1764	response to oxidative stress
FFE90_007320	COG1846	Transcriptional regulator
FFE90_007325	COG1764	response to oxidative stress
FFE90_007335	COG0590	tRNA wobble adenosine to inosine editing
FFE90_007340	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FFE90_007345	COG1404	Belongs to the peptidase S8 family
FFE90_007350	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_007355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FFE90_007360	COG1122	ATPase activity
FFE90_007365	COG4721	ABC-type cobalt transport system, permease component
FFE90_007375	COG0745	RESPONSE REGULATOR receiver
FFE90_007380	COG5002	protein histidine kinase activity
FFE90_007380	COG3850	Histidine kinase
FFE90_007385	COG3212	peptidase
FFE90_007390	COG3212	peptidase
FFE90_007405	COG2239	Acts as a magnesium transporter
FFE90_007410	COG0789	Transcriptional regulator
FFE90_007425	COG1846	Transcriptional regulator
FFE90_007430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFE90_007435	COG0726	polysaccharide deacetylase
FFE90_007440	COG1408	metallophosphoesterase
FFE90_007450	COG0463	Glycosyl transferase, family 2
FFE90_007455	COG1793	dna ligase
FFE90_007455	COG3285	dna ligase
FFE90_007460	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FFE90_007465	COG5001	Diguanylate cyclase
FFE90_007465	COG3300	MHYT domain
FFE90_007470	COG0586	Pfam SNARE associated Golgi protein
FFE90_007475	COG0861	Integral membrane protein TerC family
FFE90_007480	COG1191	sigma factor activity
FFE90_007500	COG0501	Belongs to the peptidase M48B family
FFE90_007505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FFE90_007520	COG3594	Acyltransferase
FFE90_007525	COG5002	protein histidine kinase activity
FFE90_007530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFE90_007540	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FFE90_007545	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FFE90_007550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE90_007555	COG0436	Aminotransferase
FFE90_007560	COG1850	ribulose-bisphosphate carboxylase activity
FFE90_007565	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FFE90_007570	COG0235	Class ii aldolase
FFE90_007575	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FFE90_007580	COG3339	Conserved Protein
FFE90_007595	COG3852	Histidine kinase
FFE90_007600	COG1846	Transcriptional regulator
FFE90_007605	COG1360	Flagellar Motor Protein
FFE90_007610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FFE90_007615	COG0542	response to heat
FFE90_007620	COG3949	Membrane
FFE90_007625	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FFE90_007630	COG0720	synthase
FFE90_007635	COG0602	queuosine metabolic process
FFE90_007640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FFE90_007645	COG1733	regulation of RNA biosynthetic process
FFE90_007650	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_007655	COG1388	LysM domain
FFE90_007655	COG4641	Protein conserved in bacteria
FFE90_007660	COG1388	LysM domain
FFE90_007675	COG4873	Protein conserved in bacteria
FFE90_007685	COG3773	Cell wall hydrolase
FFE90_007690	COG2244	polysaccharide biosynthetic process
FFE90_007695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_007700	COG2217	Heavy metal translocating P-type atpase
FFE90_007710	COG0006	proline dipeptidase activity
FFE90_007715	COG1609	Transcriptional regulator
FFE90_007720	COG3711	transcriptional antiterminator
FFE90_007725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_007725	COG2190	(PTS) system
FFE90_007725	COG1263	PTS System
FFE90_007730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_007735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFE90_007745	COG1533	DNA photolyase activity
FFE90_007750	COG0456	acetyltransferase
FFE90_007755	COG0840	transmembrane signaling receptor activity
FFE90_007760	COG2084	Dehydrogenase
FFE90_007765	COG2340	Cysteine-rich secretory protein family
FFE90_007770	COG0768	penicillin binding
FFE90_007775	COG4191	Histidine kinase
FFE90_007780	COG0436	Aminotransferase
FFE90_007790	COG0835	chemotaxis
FFE90_007790	COG0784	Response regulator, receiver
FFE90_007800	COG2814	Major facilitator Superfamily
FFE90_007805	COG1376	ErfK ybiS ycfS ynhG family protein
FFE90_007810	COG1408	metallophosphoesterase
FFE90_007815	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_007820	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_007825	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_007835	COG2200	EAL domain
FFE90_007840	COG4703	Protein of unknown function (DUF1797)
FFE90_007845	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FFE90_007855	COG0517	IMP dehydrogenase activity
FFE90_007860	COG0583	DNA-binding transcription factor activity
FFE90_007865	COG0716	FMN binding
FFE90_007875	COG0716	FMN binding
FFE90_007880	COG2171	N-acyltransferase activity
FFE90_007885	COG1473	amidohydrolase
FFE90_007895	COG0668	transmembrane transport
FFE90_007900	COG0450	alkyl hydroperoxide reductase
FFE90_007905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_007920	COG0746	molybdenum cofactor guanylyltransferase activity
FFE90_007925	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FFE90_007930	COG0303	'Molybdopterin
FFE90_007935	COG1763	Mo-molybdopterin cofactor biosynthetic process
FFE90_007940	COG0314	molybdopterin synthase activity
FFE90_007945	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FFE90_007950	COG1132	(ABC) transporter
FFE90_007955	COG1132	(ABC) transporter
FFE90_007965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE90_007970	COG1136	(ABC) transporter
FFE90_007975	COG0577	efflux transmembrane transporter activity
FFE90_007980	COG1349	DNA-binding transcription factor activity
FFE90_007985	COG1105	Belongs to the carbohydrate kinase PfkB family
FFE90_007990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_007990	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE90_007990	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE90_007995	COG0681	Belongs to the peptidase S26 family
FFE90_008005	COG0488	(ABC) transporter
FFE90_008010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FFE90_008015	COG2309	aminopeptidase activity
FFE90_008025	COG1077	Cell shape determining protein MreB Mrl
FFE90_008030	COG2002	toxin-antitoxin pair type II binding
FFE90_008035	COG3852	Histidine kinase
FFE90_008040	COG2105	PFAM AIG2 family protein
FFE90_008040	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FFE90_008045	COG0569	domain protein
FFE90_008050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FFE90_008055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FFE90_008065	COG0561	phosphatase activity
FFE90_008070	COG0242	peptide deformylase activity
FFE90_008080	COG0497	DNA recombination
FFE90_008085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FFE90_008090	COG0022	dehydrogenase e1 component
FFE90_008095	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE90_008100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE90_008105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_008115	COG1982	Orn Lys Arg decarboxylase major
FFE90_008120	COG4476	Belongs to the UPF0223 family
FFE90_008125	COG4493	Belongs to the UPF0637 family
FFE90_008135	COG0483	inositol monophosphate 1-phosphatase activity
FFE90_008145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FFE90_008165	COG1595	DNA-templated transcription, initiation
FFE90_008195	COG4896	Protein conserved in bacteria
FFE90_008205	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FFE90_008210	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FFE90_008215	COG2066	Belongs to the glutaminase family
FFE90_008220	COG4838	Belongs to the UPF0358 family
FFE90_008225	COG0772	Belongs to the SEDS family
FFE90_008230	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FFE90_008235	COG1612	heme a metabolic process
FFE90_008240	COG0109	protoheme IX farnesyltransferase activity
FFE90_008245	COG2010	Cytochrome c
FFE90_008245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFE90_008250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFE90_008255	COG1845	cytochrome c oxidase, subunit III
FFE90_008260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FFE90_008265	COG3336	cytochrome c oxidase
FFE90_008275	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FFE90_008280	COG2340	Cysteine-rich secretory protein family
FFE90_008295	COG3679	Belongs to the UPF0342 family
FFE90_008300	COG4471	UPF0298 protein
FFE90_008305	COG0742	ribosomal rna small subunit methyltransferase
FFE90_008310	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FFE90_008315	COG3314	Sporulation integral membrane protein YlbJ
FFE90_008320	COG1752	Esterase of the alpha-beta hydrolase superfamily
FFE90_008325	COG3480	Lon protease (S16) C-terminal proteolytic domain
FFE90_008330	COG1323	Belongs to the UPF0348 family
FFE90_008340	COG1399	metal-binding, possibly nucleic acid-binding protein
FFE90_008345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FFE90_008355	COG0454	-acetyltransferase
FFE90_008360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FFE90_008365	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FFE90_008370	COG2001	Belongs to the MraZ family
FFE90_008375	COG0275	rRNA processing
FFE90_008380	COG4839	cell division protein FtsL
FFE90_008390	COG0768	penicillin binding
FFE90_008395	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FFE90_008400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFE90_008405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FFE90_008410	COG0772	Belongs to the SEDS family
FFE90_008415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFE90_008420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FFE90_008425	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FFE90_008430	COG3879	Bacterial protein of unknown function (DUF881)
FFE90_008435	COG3879	Bacterial protein of unknown function (DUF881)
FFE90_008440	COG3856	small basic protein
FFE90_008445	COG0849	cell division
FFE90_008450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFE90_008455	COG1404	Belongs to the peptidase S8 family
FFE90_008455	COG4412	M6 family metalloprotease domain protein
FFE90_008465	COG1191	sigma factor activity
FFE90_008470	COG1191	sigma factor activity
FFE90_008475	COG1119	ATPase activity
FFE90_008480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE90_008485	COG1873	PFAM PRC-barrel domain
FFE90_008495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FFE90_008500	COG1799	cell septum assembly
FFE90_008505	COG0762	integral membrane protein
FFE90_008510	COG2302	S4 RNA-binding domain
FFE90_008515	COG3599	regulation of cell shape
FFE90_008520	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FFE90_008525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FFE90_008530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FFE90_008535	COG0564	pseudouridine synthase activity
FFE90_008540	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FFE90_008545	COG2233	PERMEase
FFE90_008550	COG0540	Belongs to the ATCase OTCase family
FFE90_008555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FFE90_008560	COG0505	Belongs to the CarA family
FFE90_008565	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FFE90_008570	COG0543	2 iron, 2 sulfur cluster binding
FFE90_008575	COG0167	dihydroorotate dehydrogenase activity
FFE90_008580	COG0284	orotidine-5'-phosphate decarboxylase activity
FFE90_008585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FFE90_008590	COG0175	sulfate reduction
FFE90_008595	COG0306	phosphate transporter
FFE90_008600	COG2046	Belongs to the sulfate adenylyltransferase family
FFE90_008605	COG0529	Catalyzes the synthesis of activated sulfate
FFE90_008610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE90_008615	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FFE90_008620	COG1648	precorrin-2 dehydrogenase activity
FFE90_008630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FFE90_008635	COG1561	YicC-like family, N-terminal region
FFE90_008640	COG2052	Domain of unknown function (DUF370)
FFE90_008645	COG0194	GDP metabolic process
FFE90_008650	COG1758	RNA polymerase activity
FFE90_008655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FFE90_008660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FFE90_008665	COG0242	peptide deformylase activity
FFE90_008670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFE90_008675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FFE90_008675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFE90_008680	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FFE90_008685	COG0631	protein serine/threonine phosphatase activity
FFE90_008690	COG0515	serine threonine protein kinase
FFE90_008690	COG2815	serine threonine protein kinase
FFE90_008695	COG1162	GTPase activity
FFE90_008700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FFE90_008705	COG1564	THIamine pyrophosphokinase
FFE90_008715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFE90_008720	COG1302	Protein conserved in bacteria
FFE90_008725	COG1461	Dihydroxyacetone kinase
FFE90_008730	COG1760	l-serine dehydratase
FFE90_008735	COG1760	l-serine dehydratase
FFE90_008740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FFE90_008745	COG2050	protein possibly involved in aromatic compounds catabolism
FFE90_008745	COG1349	DNA-binding transcription factor activity
FFE90_008750	COG0416	fatty acid biosynthetic process
FFE90_008755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FFE90_008760	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_008765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFE90_008770	COG0571	ribonuclease III activity
FFE90_008775	COG1196	nuclear chromosome segregation
FFE90_008780	COG0552	protein localization to endoplasmic reticulum
FFE90_008790	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FFE90_008795	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FFE90_008800	COG0228	four-way junction DNA binding
FFE90_008805	COG1837	Belongs to the UPF0109 family
FFE90_008815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFE90_008820	COG0336	Belongs to the RNA methyltransferase TrmD family
FFE90_008825	COG0335	large ribosomal subunit rRNA binding
FFE90_008830	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FFE90_008835	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFE90_008845	COG2257	FlhB HrpN YscU SpaS Family
FFE90_008850	COG0045	succinate-CoA ligase (ADP-forming) activity
FFE90_008855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FFE90_008860	COG0758	DNA mediated transformation
FFE90_008865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFE90_008870	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FFE90_008875	COG4974	Belongs to the 'phage' integrase family
FFE90_008880	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FFE90_008885	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FFE90_008890	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FFE90_008895	COG1815	bacterial-type flagellum-dependent cell motility
FFE90_008900	COG1558	bacterial-type flagellum-dependent cell motility
FFE90_008905	COG1677	Flagellar hook-basal body complex protein FliE
FFE90_008910	COG1766	The M ring may be actively involved in energy transduction
FFE90_008915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFE90_008920	COG1317	bacterial-type flagellum organization
FFE90_008925	COG1157	protein secretion by the type III secretion system
FFE90_008930	COG2882	bacterial-type flagellum organization
FFE90_008935	COG3334	PFAM MgtE intracellular
FFE90_008940	COG3144	bacterial-type flagellum assembly
FFE90_008945	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FFE90_008950	COG4786	Flagellar basal body rod
FFE90_008955	COG1582	Flagellar protein (FlbD)
FFE90_008960	COG1580	Controls the rotational direction of flagella during chemotaxis
FFE90_008965	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFE90_008970	COG1776	CheC inhibitor of MCP methylation
FFE90_008970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFE90_008975	COG2201	protein-glutamate methylesterase activity
FFE90_008980	COG3190	flagellar
FFE90_008985	COG1338	Plays a role in the flagellum-specific transport system
FFE90_008990	COG1987	bacterial-type flagellum assembly
FFE90_008995	COG1684	flagellar biosynthetic protein fliR
FFE90_009000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE90_009005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE90_009010	COG1419	protein localization to endoplasmic reticulum
FFE90_009015	COG0455	bacterial-type flagellum organization
FFE90_009020	COG2201	protein-glutamate methylesterase activity
FFE90_009025	COG0643	Histidine kinase
FFE90_009025	COG2198	Histidine kinase
FFE90_009030	COG0835	chemotaxis
FFE90_009035	COG1776	CheC inhibitor of MCP methylation
FFE90_009040	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FFE90_009045	COG1191	sigma factor activity
FFE90_009055	COG0052	Belongs to the universal ribosomal protein uS2 family
FFE90_009060	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFE90_009065	COG0528	UMP kinase activity
FFE90_009070	COG0233	cytoplasmic translational termination
FFE90_009075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFE90_009080	COG4589	Belongs to the CDS family
FFE90_009085	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FFE90_009090	COG0750	zinc metalloprotease
FFE90_009095	COG0442	prolyl-tRNA aminoacylation
FFE90_009100	COG2176	DNA-directed DNA polymerase activity
FFE90_009105	COG0779	Required for maturation of 30S ribosomal subunits
FFE90_009110	COG0195	Participates in both transcription termination and antitermination
FFE90_009115	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FFE90_009120	COG1358	cellular component organization or biogenesis
FFE90_009125	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FFE90_009130	COG1550	Protein conserved in bacteria
FFE90_009135	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FFE90_009140	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FFE90_009145	COG0196	riboflavin kinase activity
FFE90_009150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FFE90_009155	COG1185	polyribonucleotide nucleotidyltransferase activity
FFE90_009160	COG0726	polysaccharide deacetylase
FFE90_009165	COG0612	Peptidase, M16
FFE90_009170	COG1873	PFAM PRC-barrel domain
FFE90_009175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFE90_009180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FFE90_009185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFE90_009190	COG0527	aspartate kinase activity
FFE90_009195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFE90_009200	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FFE90_009205	COG0740	serine-type endopeptidase activity
FFE90_009215	COG1674	ftsk spoiiie
FFE90_009215	COG4980	gas vesicle protein
FFE90_009220	COG2188	Transcriptional regulator
FFE90_009230	COG0612	Peptidase, M16
FFE90_009235	COG0612	Peptidase, M16
FFE90_009240	COG0300	oxidoreductase activity
FFE90_009255	COG1426	Protein conserved in bacteria
FFE90_009260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFE90_009265	COG1546	Belongs to the CinA family
FFE90_009265	COG1058	Belongs to the CinA family
FFE90_009270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFE90_009275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FFE90_009280	COG1418	mRNA catabolic process
FFE90_009285	COG1692	metallophosphoesterase
FFE90_009290	COG2359	stage V sporulation protein S
FFE90_009295	COG1063	alcohol dehydrogenase
FFE90_009300	COG0156	8-amino-7-oxononanoate synthase activity
FFE90_009305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFE90_009310	COG4550	Control of competence regulator ComK, YlbF/YmcA
FFE90_009320	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FFE90_009325	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FFE90_009340	COG3226	Transcriptional regulator
FFE90_009345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_009355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FFE90_009360	COG3321	synthase
FFE90_009365	COG2070	2-Nitropropane dioxygenase
FFE90_009365	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FFE90_009370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFE90_009375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE90_009380	COG3425	synthase
FFE90_009385	COG1024	Enoyl-CoA hydratase
FFE90_009390	COG1024	Enoyl-CoA hydratase
FFE90_009395	COG0300	oxidoreductase activity
FFE90_009395	COG3321	synthase
FFE90_009395	COG0318	PFAM AMP-dependent synthetase and ligase
FFE90_009395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_009395	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_009400	COG4221	oxidoreductase activity
FFE90_009400	COG0300	oxidoreductase activity
FFE90_009400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFE90_009400	COG3321	synthase
FFE90_009405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_009405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFE90_009405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE90_009405	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_009405	COG3321	synthase
FFE90_009410	COG4221	oxidoreductase activity
FFE90_009410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_009410	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_009410	COG3321	synthase
FFE90_009415	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FFE90_009415	COG3321	synthase
FFE90_009415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFE90_009415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFE90_009420	COG2124	cytochrome p450
FFE90_009430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_009435	COG1404	Belongs to the peptidase S8 family
FFE90_009440	COG4195	phage-related replication protein
FFE90_009445	COG1764	response to oxidative stress
FFE90_009450	COG2076	Multidrug Resistance protein
FFE90_009455	COG2076	Multidrug Resistance protein
FFE90_009470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FFE90_009475	COG1923	regulation of RNA biosynthetic process
FFE90_009490	COG1780	Probably involved in ribonucleotide reductase function
FFE90_009495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE90_009500	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE90_009505	COG4112	unkown
FFE90_009510	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE90_009520	COG0464	growth
FFE90_009525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FFE90_009530	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FFE90_009535	COG0789	Transcriptional regulator
FFE90_009540	COG0174	glutamine synthetase
FFE90_009560	COG4282	regulation of fungal-type cell wall biogenesis
FFE90_009570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_009600	COG0135	phosphoribosylanthranilate isomerase activity
FFE90_009605	COG2211	Major facilitator Superfamily
FFE90_009610	COG3507	Belongs to the glycosyl hydrolase 43 family
FFE90_009615	COG1940	carbohydrate kinase activity
FFE90_009620	COG2115	Belongs to the xylose isomerase family
FFE90_009625	COG1070	Carbohydrate kinase
FFE90_009635	COG1525	nuclease
FFE90_009640	COG2814	Major facilitator Superfamily
FFE90_009645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFE90_009655	COG0756	dUTP diphosphatase activity
FFE90_009670	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FFE90_009695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE90_009710	COG3832	glyoxalase III activity
FFE90_009725	COG0697	spore germination
FFE90_009730	COG0531	amino acid
FFE90_009760	COG4195	phage-related replication protein
FFE90_009770	COG0346	lactoylglutathione lyase activity
FFE90_009780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FFE90_009785	COG1388	LysM domain
FFE90_009790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE90_009795	COG4224	UPF0291 protein
FFE90_009800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FFE90_009810	COG3763	UPF0154 protein
FFE90_009820	COG0785	Cytochrome C biogenesis protein
FFE90_009825	COG2201	protein-glutamate methylesterase activity
FFE90_009830	COG4846	Membrane protein involved in cytochrome C biogenesis
FFE90_009840	COG0071	Belongs to the small heat shock protein (HSP20) family
FFE90_009855	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FFE90_009860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_009880	COG0824	Thioesterase
FFE90_009890	COG4841	protein insertion into membrane
FFE90_009895	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FFE90_009900	COG1832	CoA-binding protein
FFE90_009905	COG0187	DNA topoisomerase II activity
FFE90_009910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFE90_009920	COG1115	amino acid carrier protein
FFE90_009925	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FFE90_009935	COG5520	Belongs to the glycosyl hydrolase 30 family
FFE90_009940	COG3507	Belongs to the glycosyl hydrolase 43 family
FFE90_009950	COG2246	polysaccharide biosynthetic process
FFE90_009955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE90_009960	COG0586	Pfam SNARE associated Golgi protein
FFE90_009965	COG2404	hydrolase activity, acting on ester bonds
FFE90_009970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FFE90_009975	COG1024	Enoyl-CoA hydratase
FFE90_009980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFE90_009985	COG0511	ligase activity, forming carbon-carbon bonds
FFE90_009990	COG0439	Biotin carboxylase
FFE90_009995	COG0318	PFAM AMP-dependent synthetase and ligase
FFE90_010000	COG1960	acyl-CoA dehydrogenase activity
FFE90_010015	COG1649	PFAM Uncharacterised BCR, COG1649
FFE90_010025	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FFE90_010025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_010030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_010035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_010040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_010045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_010050	COG2027	D-alanyl-D-alanine carboxypeptidase
FFE90_010055	COG2017	converts alpha-aldose to the beta-anomer
FFE90_010060	COG0534	Mate efflux family protein
FFE90_010075	COG0582	viral genome integration into host DNA
FFE90_010080	COG0166	Belongs to the GPI family
FFE90_010085	COG0405	Gamma-glutamyltransferase
FFE90_010090	COG0583	DNA-binding transcription factor activity
FFE90_010095	COG0604	alcohol dehydrogenase
FFE90_010100	COG0493	'glutamate synthase
FFE90_010105	COG0067	glutamate synthase
FFE90_010105	COG0069	glutamate synthase activity
FFE90_010105	COG0070	glutamate synthase
FFE90_010110	COG0583	DNA-binding transcription factor activity
FFE90_010115	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FFE90_010120	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFE90_010130	COG0300	oxidoreductase activity
FFE90_010135	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FFE90_010145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_010150	COG2814	Major facilitator Superfamily
FFE90_010155	COG1070	Carbohydrate kinase
FFE90_010160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFE90_010165	COG0243	molybdopterin cofactor binding
FFE90_010195	COG0840	transmembrane signaling receptor activity
FFE90_010195	COG5278	phosphoserine phosphatase activity
FFE90_010200	COG2368	4-hydroxyphenylacetate
FFE90_010205	COG4305	rare lipoprotein A
FFE90_010210	COG3619	membrane
FFE90_010215	COG3866	Pectate lyase
FFE90_010220	COG2135	peptidase activity
FFE90_010230	COG2140	Oxalate decarboxylase
FFE90_010245	COG0456	acetyltransferase
FFE90_010265	COG2720	vancomycin resistance protein
FFE90_010275	COG3655	Transcriptional regulator
FFE90_010280	COG3739	integral membrane protein
FFE90_010285	COG0583	DNA-binding transcription factor activity
FFE90_010290	COG0697	spore germination
FFE90_010300	COG0693	protein deglycase activity
FFE90_010305	COG2367	Beta-lactamase
FFE90_010330	COG0574	Belongs to the PEP-utilizing enzyme family
FFE90_010330	COG3848	Pyruvate phosphate dikinase
FFE90_010335	COG0726	polysaccharide deacetylase
FFE90_010345	COG2314	TM2 domain
FFE90_010350	COG1396	sequence-specific DNA binding
FFE90_010365	COG2135	peptidase activity
FFE90_010405	COG0457	Tetratricopeptide repeat
FFE90_010430	COG5290	Psort location Cytoplasmic, score
FFE90_010455	COG5444	nuclease activity
FFE90_010460	COG4282	regulation of fungal-type cell wall biogenesis
FFE90_010465	COG1231	oxidoreductase activity
FFE90_010470	COG5434	Belongs to the glycosyl hydrolase 28 family
FFE90_010475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE90_010480	COG2207	Transcriptional regulator
FFE90_010480	COG0662	Cupin 2, conserved barrel domain protein
FFE90_010485	COG0456	acetyltransferase
FFE90_010490	COG1309	transcriptional regulator
FFE90_010495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_010500	COG3708	Transcriptional regulator
FFE90_010505	COG2378	regulation of single-species biofilm formation
FFE90_010515	COG0640	Transcriptional regulator
FFE90_010520	COG0741	lytic transglycosylase activity
FFE90_010525	COG2322	membrane
FFE90_010540	COG1619	proteins homologs of microcin C7 resistance protein MccF
FFE90_010545	COG3239	Fatty acid desaturase
FFE90_010550	COG4585	Histidine kinase
FFE90_010555	COG2197	response regulator
FFE90_010560	COG1388	LysM domain
FFE90_010560	COG3584	3D domain protein
FFE90_010565	COG0514	ATP-dependent DNA helicase (RecQ)
FFE90_010580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FFE90_010585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FFE90_010600	COG0071	Belongs to the small heat shock protein (HSP20) family
FFE90_010625	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_010630	COG1657	PFAM Prenyltransferase squalene oxidase
FFE90_010635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FFE90_010640	COG0733	neurotransmitter:sodium symporter activity
FFE90_010645	COG0385	Bile acid
FFE90_010650	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE90_010655	COG0567	Dehydrogenase, E1 component
FFE90_010660	COG4548	von Willebrand factor, type A
FFE90_010665	COG0714	Associated with various cellular activities
FFE90_010670	COG2032	superoxide dismutase activity
FFE90_010675	COG1388	LysM domain
FFE90_010675	COG0791	NLP P60 protein
FFE90_010680	COG1819	glycosyl
FFE90_010685	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FFE90_010690	COG0534	Mate efflux family protein
FFE90_010695	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_010700	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFE90_010705	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFE90_010715	COG2962	Rard protein
FFE90_010730	COG2610	gluconate transmembrane transporter activity
FFE90_010735	COG1942	4-Oxalocrotonate Tautomerase
FFE90_010740	COG1733	regulation of RNA biosynthetic process
FFE90_010745	COG0778	Nitroreductase
FFE90_010750	COG0400	carboxylic ester hydrolase activity
FFE90_010755	COG0346	lactoylglutathione lyase activity
FFE90_010765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE90_010770	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_010770	COG0793	Belongs to the peptidase S41A family
FFE90_010775	COG2226	methyltransferase
FFE90_010785	COG1876	peptidase activity
FFE90_010790	COG0813	purine-nucleoside phosphorylase activity
FFE90_010805	COG0671	phosphoesterase, PA-phosphatase related
FFE90_010830	COG4479	Belongs to the UPF0346 family
FFE90_010840	COG1509	lysine 2,3-aminomutase activity
FFE90_010845	COG0456	acetyltransferase
FFE90_010850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE90_010855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FFE90_010860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FFE90_010865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFE90_010880	COG0456	acetyltransferase
FFE90_010885	COG0463	Glycosyl transferase, family 2
FFE90_010900	COG4641	Protein conserved in bacteria
FFE90_010905	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
FFE90_010910	COG1086	Polysaccharide biosynthesis protein
FFE90_010920	COG3331	DNA recombination
FFE90_010975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FFE90_011010	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FFE90_011015	COG0756	dUTP diphosphatase activity
FFE90_011020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_011040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE90_011040	COG1372	Participates in initiation and elongation during chromosome replication
FFE90_011045	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE90_011045	COG1372	Participates in initiation and elongation during chromosome replication
FFE90_011050	COG1780	Probably involved in ribonucleotide reductase function
FFE90_011140	COG0270	DNA (cytosine-5-)-methyltransferase activity
FFE90_011150	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FFE90_011155	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFE90_011180	COG3584	3D domain protein
FFE90_011185	COG0587	DNA-directed DNA polymerase activity
FFE90_011190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFE90_011195	COG0358	DNA primase activity
FFE90_011200	COG0305	Participates in initiation and elongation during chromosome replication
FFE90_011210	COG2887	Belongs to the helicase family. UvrD subfamily
FFE90_011240	COG5434	Belongs to the glycosyl hydrolase 28 family
FFE90_011240	COG3420	alginic acid biosynthetic process
FFE90_011245	COG4195	phage-related replication protein
FFE90_011260	COG2135	peptidase activity
FFE90_011265	COG1793	dna ligase
FFE90_011320	COG4474	Belongs to the UPF0398 family
FFE90_011330	COG1388	LysM domain
FFE90_011350	COG3646	Phage regulatory protein
FFE90_011350	COG3645	SOS response
FFE90_011405	COG3655	Transcriptional regulator
FFE90_011420	COG0582	viral genome integration into host DNA
FFE90_011500	COG3655	Transcriptional regulator
FFE90_011540	COG1395	domain, Protein
FFE90_011555	COG0776	regulation of translation
FFE90_011590	COG4373	Mu-like prophage FluMu protein gp28
FFE90_011690	COG0582	viral genome integration into host DNA
FFE90_011720	COG1196	nuclear chromosome segregation
FFE90_011720	COG0741	lytic transglycosylase activity
FFE90_011720	COG0739	heme binding
FFE90_011730	COG2433	Pfam Transposase IS66
FFE90_011740	COG5434	Belongs to the glycosyl hydrolase 28 family
FFE90_011740	COG4632	Exopolysaccharide biosynthesis protein
FFE90_011755	COG5632	N-Acetylmuramoyl-L-alanine amidase
FFE90_011770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FFE90_011775	COG0463	Glycosyl transferase, family 2
FFE90_011780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_011785	COG3271	cysteine-type peptidase activity
FFE90_011785	COG2274	protein secretion by the type I secretion system
FFE90_011800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFE90_011830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE90_011845	COG5444	nuclease activity
FFE90_011850	COG4282	regulation of fungal-type cell wall biogenesis
FFE90_011865	COG1525	nuclease
FFE90_011875	COG2746	aminoglycoside 3-N-acetyltransferase activity
FFE90_011900	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE90_011905	COG1086	Polysaccharide biosynthesis protein
FFE90_011910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFE90_011915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFE90_011920	COG1846	Transcriptional regulator
FFE90_011925	COG0534	Mate efflux family protein
FFE90_011935	COG4698	Protein conserved in bacteria
FFE90_011940	COG2755	lipolytic protein G-D-S-L family
FFE90_011945	COG1999	signal sequence binding
FFE90_011955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFE90_011960	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FFE90_011965	COG1272	protein, Hemolysin III
FFE90_011970	COG0204	Acyl-transferase
FFE90_011975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFE90_011980	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FFE90_011985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FFE90_011995	COG2521	methyltransferase
FFE90_011995	COG2136	Putative SAM-dependent methyltransferase
FFE90_012005	COG0129	dihydroxy-acid dehydratase activity
FFE90_012010	COG1413	lyase activity
FFE90_012015	COG1418	mRNA catabolic process
FFE90_012020	COG0386	Belongs to the glutathione peroxidase family
FFE90_012025	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FFE90_012030	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFE90_012040	COG1278	Cold shock
FFE90_012060	COG0328	RNA-DNA hybrid ribonuclease activity
FFE90_012065	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FFE90_012070	COG0328	RNA-DNA hybrid ribonuclease activity
FFE90_012080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFE90_012095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FFE90_012105	COG1755	Isoprenylcysteine carboxyl methyltransferase
FFE90_012110	COG3424	synthase
FFE90_012115	COG2233	PERMEase
FFE90_012120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFE90_012125	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FFE90_012135	COG0800	Aldolase
FFE90_012140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE90_012145	COG1609	Transcriptional regulator
FFE90_012150	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FFE90_012155	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_012160	COG1199	ATP-dependent helicase activity
FFE90_012175	COG0116	Belongs to the methyltransferase superfamily
FFE90_012190	COG4474	Belongs to the UPF0398 family
FFE90_012205	COG3359	exonuclease
FFE90_012210	COG1111	helicase
FFE90_012210	COG1205	dead DEAH box helicase
FFE90_012215	COG2190	(PTS) system
FFE90_012220	COG0071	Belongs to the small heat shock protein (HSP20) family
FFE90_012255	COG3331	DNA recombination
FFE90_012260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE90_012260	COG4499	WXG100 protein secretion system (Wss), protein YukC
FFE90_012270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FFE90_012275	COG3935	DnaD domain protein
FFE90_012280	COG0017	Asparaginyl-tRNA synthetase
FFE90_012285	COG0436	Aminotransferase
FFE90_012290	COG5353	protein conserved in bacteria
FFE90_012300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFE90_012300	COG1199	ATP-dependent helicase activity
FFE90_012305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FFE90_012310	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FFE90_012315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FFE90_012320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FFE90_012320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FFE90_012325	COG0617	tRNA 3'-terminal CCA addition
FFE90_012330	COG0438	transferase activity, transferring glycosyl groups
FFE90_012335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FFE90_012340	COG1803	Methylglyoxal synthase
FFE90_012345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FFE90_012350	COG1694	Mazg nucleotide pyrophosphohydrolase
FFE90_012355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFE90_012365	COG4347	Protein of unknown function (DUF1405)
FFE90_012370	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FFE90_012370	COG2010	Cytochrome c
FFE90_012375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FFE90_012380	COG0723	plastoquinol--plastocyanin reductase activity
FFE90_012390	COG5582	Belongs to the UPF0302 family
FFE90_012395	COG0457	Tetratricopeptide repeat
FFE90_012400	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FFE90_012405	COG0287	Prephenate dehydrogenase
FFE90_012410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFE90_012415	COG0159	tryptophan synthase activity
FFE90_012420	COG0133	tryptophan synthase activity
FFE90_012425	COG0135	phosphoribosylanthranilate isomerase activity
FFE90_012435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FFE90_012440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FFE90_012445	COG4401	Chorismate mutase type I
FFE90_012450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FFE90_012455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FFE90_012460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FFE90_012465	COG0105	UTP biosynthetic process
FFE90_012470	COG0142	geranyltranstransferase activity
FFE90_012475	COG2226	methyltransferase
FFE90_012480	COG0142	geranyltranstransferase activity
FFE90_012490	COG0302	gtp cyclohydrolase
FFE90_012495	COG0776	regulation of translation
FFE90_012500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FFE90_012515	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FFE90_012520	COG1160	GTP binding
FFE90_012545	COG1304	FMN binding
FFE90_012550	COG0539	negative regulation of cytoplasmic translation
FFE90_012555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FFE90_012565	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FFE90_012570	COG2959	enzyme of heme biosynthesis
FFE90_012575	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_012575	COG3773	Cell wall hydrolase
FFE90_012580	COG2339	peptidase activity
FFE90_012585	COG0492	ferredoxin-NADP+ reductase activity
FFE90_012590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FFE90_012595	COG4862	establishment of competence for transformation
FFE90_012600	COG1408	metallophosphoesterase
FFE90_012610	COG1388	LysM domain
FFE90_012615	COG1266	CAAX protease self-immunity
FFE90_012620	COG0514	ATP-dependent DNA helicase (RecQ)
FFE90_012625	COG4955	Helix-turn-helix domain
FFE90_012630	COG1141	Ferredoxin
FFE90_012635	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FFE90_012640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFE90_012645	COG0710	3-dehydroquinate dehydratase activity
FFE90_012655	COG1595	DNA-templated transcription, initiation
FFE90_012660	COG5002	protein histidine kinase activity
FFE90_012665	COG0745	RESPONSE REGULATOR receiver
FFE90_012670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE90_012675	COG1333	cytochrome c biogenesis protein
FFE90_012680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_012685	COG1187	pseudouridine synthase activity
FFE90_012690	COG0700	Nucleoside recognition
FFE90_012695	COG2715	membrane protein required for spore maturation
FFE90_012700	COG1686	Belongs to the peptidase S11 family
FFE90_012710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FFE90_012715	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FFE90_012720	COG1547	Domain of unknown function (DUF309)
FFE90_012725	COG0456	acetyltransferase
FFE90_012730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FFE90_012735	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFE90_012735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFE90_012740	COG0307	riboflavin synthase, alpha
FFE90_012745	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFE90_012745	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFE90_012755	COG0681	Belongs to the peptidase S26 family
FFE90_012765	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
FFE90_012790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FFE90_012800	COG4086	secreted protein
FFE90_012805	COG0019	diaminopimelate decarboxylase activity
FFE90_012810	COG0697	spore germination
FFE90_012825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FFE90_012845	COG1191	sigma factor activity
FFE90_012850	COG2172	sigma factor antagonist activity
FFE90_012855	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_012860	COG1686	Belongs to the peptidase S11 family
FFE90_012865	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FFE90_012870	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FFE90_012875	COG4974	Belongs to the 'phage' integrase family
FFE90_012885	COG0735	belongs to the Fur family
FFE90_012890	COG1300	Membrane
FFE90_012900	COG0281	malic enzyme
FFE90_012905	COG1757	Na H antiporter
FFE90_012910	COG1027	Aspartate ammonia-lyase
FFE90_012915	COG0252	asparaginase activity
FFE90_012920	COG1396	sequence-specific DNA binding
FFE90_012925	COG1379	DNA repair
FFE90_012930	COG0494	nUDIX hydrolase
FFE90_012940	COG0667	Aldo Keto reductase
FFE90_012950	COG1073	alpha beta
FFE90_012960	COG4918	Iron-sulphur cluster biosynthesis
FFE90_012965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FFE90_012965	COG0456	acetyltransferase
FFE90_012970	COG2329	Antibiotic biosynthesis monooxygenase
FFE90_012975	COG0456	acetyltransferase
FFE90_012985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFE90_012995	COG2211	Major facilitator Superfamily
FFE90_013000	COG0346	lactoylglutathione lyase activity
FFE90_013005	COG1072	(Pantothenic acid kinase))
FFE90_013010	COG3048	D-serine ammonia-lyase activity
FFE90_013015	COG0300	oxidoreductase activity
FFE90_013020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_013025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFE90_013030	COG4187	Peptidase family M20/M25/M40
FFE90_013035	COG1902	pentaerythritol trinitrate reductase activity
FFE90_013040	COG0596	Alpha beta hydrolase
FFE90_013050	COG1234	tRNA 3'-trailer cleavage
FFE90_013055	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FFE90_013060	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FFE90_013065	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFE90_013075	COG0706	membrane insertase activity
FFE90_013080	COG3361	conserved protein (COG2071)
FFE90_013085	COG2195	Cleaves the N-terminal amino acid of tripeptides
FFE90_013090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FFE90_013095	COG0346	lactoylglutathione lyase activity
FFE90_013100	COG1376	ErfK ybiS ycfS ynhG family protein
FFE90_013105	COG4129	membrane
FFE90_013110	COG1126	abc transporter atp-binding protein
FFE90_013115	COG0765	amino acid transport
FFE90_013120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE90_013130	COG1597	lipid kinase activity
FFE90_013135	COG2814	Major facilitator Superfamily
FFE90_013140	COG0789	Transcriptional regulator
FFE90_013140	COG4978	Transcriptional regulator
FFE90_013145	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE90_013150	COG0022	dehydrogenase e1 component
FFE90_013155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FFE90_013160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE90_013165	COG3426	butyrate kinase activity
FFE90_013170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FFE90_013175	COG0280	phosphate acetyltransferase
FFE90_013180	COG3829	transcription factor binding
FFE90_013180	COG3290	protein histidine kinase activity
FFE90_013190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FFE90_013195	COG2079	MmgE PrpD family protein
FFE90_013200	COG0372	Belongs to the citrate synthase family
FFE90_013205	COG1960	acyl-CoA dehydrogenase activity
FFE90_013210	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFE90_013215	COG0183	Belongs to the thiolase family
FFE90_013220	COG0584	glycerophosphoryl diester phosphodiesterase
FFE90_013225	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE90_013240	COG1902	pentaerythritol trinitrate reductase activity
FFE90_013245	COG0745	RESPONSE REGULATOR receiver
FFE90_013250	COG0750	zinc metalloprotease
FFE90_013255	COG0497	DNA recombination
FFE90_013260	COG1438	arginine binding
FFE90_013265	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FFE90_013270	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FFE90_013275	COG0142	geranyltranstransferase activity
FFE90_013280	COG1722	exodeoxyribonuclease VII activity
FFE90_013285	COG1570	exodeoxyribonuclease VII activity
FFE90_013290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFE90_013295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFE90_013300	COG1302	Protein conserved in bacteria
FFE90_013305	COG0439	Biotin carboxylase
FFE90_013310	COG0511	ligase activity, forming carbon-carbon bonds
FFE90_013350	COG3854	ATPases associated with a variety of cellular activities
FFE90_013360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFE90_013365	COG0006	proline dipeptidase activity
FFE90_013370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFE90_013380	COG3872	metal-dependent enzyme
FFE90_013390	COG1752	Esterase of the alpha-beta hydrolase superfamily
FFE90_013395	COG1321	iron dependent repressor
FFE90_013400	COG0095	Lipoate-protein ligase
FFE90_013405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE90_013410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFE90_013415	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFE90_013420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFE90_013425	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FFE90_013440	COG1396	sequence-specific DNA binding
FFE90_013450	COG0681	Belongs to the peptidase S26 family
FFE90_013475	COG4940	Competence protein ComGF
FFE90_013485	COG4970	Tfp pilus assembly protein FimT
FFE90_013490	COG4537	Required for transformation and DNA binding
FFE90_013495	COG1459	type II secretion system
FFE90_013500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FFE90_013510	COG0598	Magnesium transport protein CorA
FFE90_013515	COG1253	flavin adenine dinucleotide binding
FFE90_013520	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_013530	COG1393	Belongs to the ArsC family
FFE90_013540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_013550	COG0011	TIGRFAM Protein of
FFE90_013560	COG2866	Carboxypeptidase
FFE90_013565	COG1368	sulfuric ester hydrolase activity
FFE90_013570	COG1940	carbohydrate kinase activity
FFE90_013575	COG4483	Protein conserved in bacteria
FFE90_013580	COG0705	Rhomboid family
FFE90_013580	COG0457	Tetratricopeptide repeat
FFE90_013590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FFE90_013595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFE90_013600	COG0438	transferase activity, transferring glycosyl groups
FFE90_013615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFE90_013620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FFE90_013625	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FFE90_013630	COG0581	inorganic phosphate transmembrane transporter activity
FFE90_013635	COG0573	inorganic phosphate transmembrane transporter activity
FFE90_013640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FFE90_013650	COG0477	Major facilitator Superfamily
FFE90_013655	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FFE90_013660	COG2839	Protein conserved in bacteria
FFE90_013665	COG5521	maltodextrose utilization protein MalA
FFE90_013675	COG1388	LysM domain
FFE90_013680	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FFE90_013685	COG4709	membrane
FFE90_013690	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FFE90_013695	COG0735	belongs to the Fur family
FFE90_013700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFE90_013710	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FFE90_013715	COG0513	Belongs to the DEAD box helicase family
FFE90_013725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FFE90_013730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FFE90_013735	COG2384	SAM-dependent methyltransferase
FFE90_013740	COG2010	Cytochrome c
FFE90_013750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFE90_013755	COG0358	DNA primase activity
FFE90_013760	COG1671	Belongs to the UPF0178 family
FFE90_013765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FFE90_013770	COG0517	IMP dehydrogenase activity
FFE90_013775	COG0751	glycine-tRNA ligase activity
FFE90_013780	COG0752	glycyl-tRNA synthetase alpha subunit
FFE90_013785	COG1381	Involved in DNA repair and RecF pathway recombination
FFE90_013795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFE90_013800	COG0295	cytidine deaminase activity
FFE90_013805	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FFE90_013810	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFE90_013815	COG1480	7TM receptor with intracellular HD hydrolase
FFE90_013820	COG1702	phosphate starvation-inducible protein PhoH
FFE90_013825	COG0561	phosphatase activity
FFE90_013840	COG4864	UPF0365 protein
FFE90_013845	COG1030	water channel activity
FFE90_013850	COG1610	YqeY-like protein
FFE90_013855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FFE90_013860	COG1283	sodium-dependent phosphate transmembrane transporter activity
FFE90_013865	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFE90_013870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FFE90_013875	COG2264	protein methyltransferase activity
FFE90_013880	COG0484	heat shock protein binding
FFE90_013885	COG0443	Heat shock 70 kDa protein
FFE90_013890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FFE90_013895	COG1420	regulation of RNA biosynthetic process
FFE90_013900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE90_013905	COG0481	GTPase activity
FFE90_013915	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE90_013920	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FFE90_013925	COG0268	Binds directly to 16S ribosomal RNA
FFE90_013930	COG1466	dna polymerase III delta subunit
FFE90_013945	COG2333	competence protein COMEC
FFE90_013945	COG0658	competence protein
FFE90_013950	COG2131	deaminase
FFE90_013955	COG1596	polysaccharide export
FFE90_013955	COG1555	photosystem II stabilization
FFE90_013960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFE90_013965	COG2226	methyltransferase
FFE90_013970	COG0799	negative regulation of ribosome biogenesis
FFE90_013975	COG1713	HD superfamily hydrolase involved in NAD metabolism
FFE90_013980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFE90_013985	COG1534	Rna-binding protein
FFE90_013990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFE90_013995	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FFE90_014000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FFE90_014010	COG2755	lipolytic protein G-D-S-L family
FFE90_014015	COG5632	N-Acetylmuramoyl-L-alanine amidase
FFE90_014015	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_014020	COG0398	Pfam SNARE associated Golgi protein
FFE90_014025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FFE90_014035	COG3209	COG3209 Rhs family protein
FFE90_014045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE90_014055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFE90_014060	COG0798	PFAM Bile acid sodium symporter
FFE90_014065	COG0346	lactoylglutathione lyase activity
FFE90_014070	COG0640	Transcriptional regulator
FFE90_014075	COG3403	YqcI/YcgG family
FFE90_014080	COG0457	Tetratricopeptide repeat
FFE90_014095	COG5444	nuclease activity
FFE90_014120	COG5632	N-Acetylmuramoyl-L-alanine amidase
FFE90_014120	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_014125	COG4824	toxin secretion phage lysis holin
FFE90_014155	COG3778	Protein conserved in bacteria
FFE90_014160	COG3299	homolog of phage Mu protein gp47
FFE90_014165	COG3628	GPW Gp25 family protein
FFE90_014175	COG4193	domain, Protein
FFE90_014180	COG1652	LysM domain
FFE90_014185	COG5280	Phage tail tape measure protein TP901
FFE90_014185	COG3953	SLT domain
FFE90_014250	COG4653	Phage capsid family
FFE90_014255	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FFE90_014265	COG2369	cell adhesion
FFE90_014270	COG5518	Phage portal protein
FFE90_014275	COG1783	phage Terminase large subunit
FFE90_014280	COG5484	DNA packaging
FFE90_014290	COG3677	Transposase
FFE90_014305	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
FFE90_014315	COG1484	DNA-dependent DNA replication
FFE90_014320	COG3935	DnaD domain protein
FFE90_014325	COG3723	Recombinational DNA repair protein, rece pathway
FFE90_014330	COG5377	YqaJ viral recombinase family
FFE90_014360	COG1476	TRANSCRIPTIONal
FFE90_014365	COG3620	sequence-specific DNA binding
FFE90_014375	COG0563	adenylate kinase activity
FFE90_014380	COG2856	Zn peptidase
FFE90_014405	COG3223	Belongs to the PsiE family
FFE90_014410	COG0642	Histidine kinase
FFE90_014410	COG5002	protein histidine kinase activity
FFE90_014415	COG0745	RESPONSE REGULATOR receiver
FFE90_014420	COG2311	Membrane
FFE90_014430	COG0454	-acetyltransferase
FFE90_014435	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFE90_014445	COG0730	response to heat
FFE90_014450	COG0425	Belongs to the sulfur carrier protein TusA family
FFE90_014455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_014455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE90_014465	COG0425	Belongs to the sulfur carrier protein TusA family
FFE90_014465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE90_014475	COG2210	Belongs to the sulfur carrier protein TusA family
FFE90_014480	COG1937	Protein conserved in bacteria
FFE90_014495	COG0662	Cupin 2, conserved barrel domain protein
FFE90_014510	COG4978	Transcriptional regulator
FFE90_014510	COG0789	Transcriptional regulator
FFE90_014515	COG2814	Major facilitator Superfamily
FFE90_014520	COG0456	acetyltransferase
FFE90_014525	COG1253	flavin adenine dinucleotide binding
FFE90_014535	COG0697	spore germination
FFE90_014540	COG0583	DNA-binding transcription factor activity
FFE90_014545	COG2072	flavoprotein involved in K transport
FFE90_014550	COG1230	cation diffusion facilitator family transporter
FFE90_014555	COG1942	4-Oxalocrotonate Tautomerase
FFE90_014560	COG0583	DNA-binding transcription factor activity
FFE90_014570	COG1114	Component of the transport system for branched-chain amino acids
FFE90_014575	COG1687	branched-chain amino acid
FFE90_014580	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FFE90_014585	COG1522	sequence-specific DNA binding
FFE90_014590	COG2732	(Barnase) inhibitor
FFE90_014595	COG2124	cytochrome p450
FFE90_014605	COG1335	isochorismatase
FFE90_014620	COG2318	DinB family
FFE90_014630	COG2070	2-Nitropropane dioxygenase
FFE90_014645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFE90_014665	COG3443	Belongs to the bacterial solute-binding protein 9 family
FFE90_014670	COG1595	DNA-templated transcription, initiation
FFE90_014675	COG0667	Aldo Keto reductase
FFE90_014680	COG2851	Citrate transporter
FFE90_014685	COG0583	DNA-binding transcription factor activity
FFE90_014690	COG2828	Protein conserved in bacteria
FFE90_014695	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_014700	COG5566	PFAM Mor transcription activator
FFE90_014705	COG0596	Alpha beta hydrolase
FFE90_014710	COG4991	sh3 domain protein
FFE90_014715	COG4991	sh3 domain protein
FFE90_014725	COG0346	lactoylglutathione lyase activity
FFE90_014735	COG5577	PFAM Coat F domain
FFE90_014740	COG1063	alcohol dehydrogenase
FFE90_014750	COG5577	PFAM Coat F domain
FFE90_014755	COG0789	Transcriptional regulator
FFE90_014765	COG1064	alcohol dehydrogenase
FFE90_014770	COG0693	protein deglycase activity
FFE90_014775	COG1621	beta-fructofuranosidase activity
FFE90_014780	COG3716	PTS system mannose fructose sorbose family IID component
FFE90_014785	COG3715	PTS system
FFE90_014790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_014795	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_014800	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FFE90_014800	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FFE90_014810	COG1113	amino acid transport
FFE90_014815	COG1280	lysine exporter protein (LysE YggA)
FFE90_014820	COG1378	Sugar-specific transcriptional regulator TrmB
FFE90_014825	COG1595	DNA-templated transcription, initiation
FFE90_014835	COG2755	lipolytic protein G-D-S-L family
FFE90_014835	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FFE90_014845	COG2124	cytochrome p450
FFE90_014845	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FFE90_014850	COG1309	transcriptional regulator
FFE90_014855	COG2226	methyltransferase
FFE90_014870	COG2116	formate transmembrane transporter activity
FFE90_014875	COG5609	conserved protein (DUF2294)
FFE90_014880	COG3383	formate dehydrogenase (NAD+) activity
FFE90_014885	COG2427	Protein of unknown function (DUF1641)
FFE90_014895	COG0626	cystathionine gamma-synthase activity
FFE90_014900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FFE90_014905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFE90_014910	COG2226	methyltransferase
FFE90_014925	COG0768	penicillin binding
FFE90_014930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFE90_014935	COG0572	uridine kinase
FFE90_014955	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFE90_014960	COG3906	Belongs to the UPF0473 family
FFE90_014965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FFE90_014970	COG4472	Bacterial protein of unknown function (DUF965)
FFE90_014975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFE90_014980	COG0628	permease
FFE90_014985	COG1126	abc transporter atp-binding protein
FFE90_014990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE90_014995	COG0765	amino acid transport
FFE90_015000	COG0765	amino acid transport
FFE90_015015	COG3881	PFAM PRC-barrel domain
FFE90_015020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FFE90_015025	COG0457	Tetratricopeptide repeat
FFE90_015030	COG0482	sulfurtransferase activity
FFE90_015035	COG1104	cysteine desulfurase activity
FFE90_015040	COG1959	2 iron, 2 sulfur cluster binding
FFE90_015045	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FFE90_015050	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FFE90_015060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FFE90_015065	COG0124	histidyl-tRNA synthetase
FFE90_015075	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE90_015075	COG3103	Sh3 type 3 domain protein
FFE90_015075	COG4991	sh3 domain protein
FFE90_015080	COG1490	D-aminoacyl-tRNA deacylase activity
FFE90_015085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FFE90_015090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFE90_015095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FFE90_015095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFE90_015100	COG5416	Lipopolysaccharide assembly protein A domain
FFE90_015105	COG0490	domain, Protein
FFE90_015110	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFE90_015110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFE90_015120	COG2244	polysaccharide biosynthetic process
FFE90_015125	COG2323	membrane
FFE90_015135	COG1862	Preprotein translocase
FFE90_015140	COG0343	queuine tRNA-ribosyltransferase activity
FFE90_015145	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FFE90_015155	COG2255	four-way junction helicase activity
FFE90_015160	COG0632	four-way junction helicase activity
FFE90_015170	COG2814	Major facilitator Superfamily
FFE90_015175	COG0673	inositol 2-dehydrogenase activity
FFE90_015180	COG2112	serine threonine protein kinase
FFE90_015200	COG1115	amino acid carrier protein
FFE90_015205	COG0217	transcriptional regulatory protein
FFE90_015215	COG1388	LysM domain
FFE90_015220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FFE90_015225	COG0157	Belongs to the NadC ModD family
FFE90_015230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FFE90_015235	COG1104	cysteine desulfurase activity
FFE90_015240	COG1827	regulation of RNA biosynthetic process
FFE90_015245	COG0077	Prephenate dehydratase
FFE90_015250	COG4492	Belongs to the UPF0735 family
FFE90_015255	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFE90_015260	COG3290	protein histidine kinase activity
FFE90_015270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FFE90_015275	COG2868	ribosomal protein
FFE90_015280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FFE90_015285	COG1994	Peptidase M50
FFE90_015290	COG0739	heme binding
FFE90_015295	COG2894	cell division
FFE90_015300	COG0850	regulation of cytokinetic process
FFE90_015305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FFE90_015310	COG1792	Involved in formation and maintenance of cell shape
FFE90_015315	COG1077	Cell shape determining protein MreB Mrl
FFE90_015320	COG2003	Belongs to the UPF0758 family
FFE90_015325	COG0424	maF-like protein
FFE90_015335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FFE90_015340	COG0285	dihydrofolate synthase activity
FFE90_015345	COG0525	valine-tRNA ligase activity
FFE90_015355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFE90_015360	COG1388	LysM domain
FFE90_015365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFE90_015370	COG0113	porphobilinogen synthase activity
FFE90_015375	COG1587	Uroporphyrinogen-III synthase
FFE90_015380	COG0181	hydroxymethylbilane synthase activity
FFE90_015385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE90_015390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FFE90_015400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FFE90_015405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FFE90_015410	COG0470	DNA polymerase III
FFE90_015410	COG1067	ATP-dependent peptidase activity
FFE90_015415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFE90_015420	COG0544	peptidyl-prolyl cis-trans isomerase activity
FFE90_015425	COG1477	protein flavinylation
FFE90_015425	COG0457	Tetratricopeptide repeat
FFE90_015430	COG0066	3-isopropylmalate dehydratase activity
FFE90_015435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FFE90_015440	COG0473	3-isopropylmalate dehydrogenase activity
FFE90_015445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FFE90_015450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FFE90_015455	COG0440	acetolactate synthase activity
FFE90_015460	COG0028	Belongs to the TPP enzyme family
FFE90_015470	COG0454	-acetyltransferase
FFE90_015475	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FFE90_015485	COG0622	Phosphoesterase
FFE90_015490	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FFE90_015495	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FFE90_015500	COG5401	PFAM Sporulation and spore germination
FFE90_015505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFE90_015510	COG1846	Transcriptional regulator
FFE90_015515	COG2197	response regulator
FFE90_015520	COG0824	Thioesterase
FFE90_015525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFE90_015530	COG1053	succinate dehydrogenase
FFE90_015535	COG2009	succinate dehydrogenase
FFE90_015540	COG1719	4-vinyl reductase, 4VR
FFE90_015545	COG0527	aspartate kinase activity
FFE90_015555	COG0322	excinuclease ABC activity
FFE90_015560	COG3118	belongs to the thioredoxin family
FFE90_015570	COG3534	alpha-L-arabinofuranosidase
FFE90_015575	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FFE90_015580	COG2086	electron transfer activity
FFE90_015585	COG1024	Enoyl-CoA hydratase
FFE90_015590	COG1309	transcriptional regulator
FFE90_015595	COG0318	PFAM AMP-dependent synthetase and ligase
FFE90_015600	COG3766	membrane
FFE90_015605	COG1193	negative regulation of DNA recombination
FFE90_015610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FFE90_015610	COG1796	DNA polymerase
FFE90_015615	COG1286	toxin biosynthetic process
FFE90_015620	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FFE90_015625	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFE90_015630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE90_015630	COG0072	phenylalanine-tRNA ligase activity
FFE90_015635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FFE90_015645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE90_015655	COG3835	regulator
FFE90_015660	COG0277	FAD linked oxidase domain protein
FFE90_015665	COG0247	lactate metabolic process
FFE90_015670	COG0346	lactoylglutathione lyase activity
FFE90_015680	COG1966	Carbon starvation protein
FFE90_015685	COG3534	alpha-L-arabinofuranosidase
FFE90_015690	COG0395	ABC-type sugar transport system, permease component
FFE90_015695	COG1175	transmembrane transport
FFE90_015700	COG1653	transport
FFE90_015705	COG0371	Dehydrogenase
FFE90_015710	COG0647	UMP catabolic process
FFE90_015715	COG0235	Class ii aldolase
FFE90_015720	COG1069	ribulokinase activity
FFE90_015725	COG2160	L-arabinose isomerase activity
FFE90_015730	COG3507	Belongs to the glycosyl hydrolase 43 family
FFE90_015735	COG1363	Peptidase, m42
FFE90_015745	COG3326	Membrane
FFE90_015750	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FFE90_015755	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FFE90_015760	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFE90_015770	COG1346	cytolysis
FFE90_015775	COG1380	Effector of murein hydrolase LrgA
FFE90_015780	COG3279	Response regulator of the LytR AlgR family
FFE90_015785	COG3275	phosphorelay sensor kinase activity
FFE90_015795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FFE90_015805	COG0398	Pfam SNARE associated Golgi protein
FFE90_015810	COG1484	DNA-dependent DNA replication
FFE90_015815	COG3611	Membrane attachment protein
FFE90_015820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FFE90_015825	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FFE90_015830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FFE90_015835	COG1733	regulation of RNA biosynthetic process
FFE90_015840	COG2814	Major facilitator Superfamily
FFE90_015845	COG0656	L-ascorbic acid biosynthetic process
FFE90_015850	COG0237	dephospho-CoA kinase activity
FFE90_015855	COG1971	Probably functions as a manganese efflux pump
FFE90_015860	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FFE90_015865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFE90_015865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFE90_015870	COG5002	protein histidine kinase activity
FFE90_015875	COG0745	RESPONSE REGULATOR receiver
FFE90_015880	COG0039	L-malate dehydrogenase activity
FFE90_015885	COG0538	isocitrate dehydrogenase activity
FFE90_015890	COG0372	Belongs to the citrate synthase family
FFE90_015895	COG2707	UPF0756 membrane protein
FFE90_015900	COG0628	permease
FFE90_015905	COG3030	protein affecting phage T7 exclusion by the F plasmid
FFE90_015910	COG0469	pyruvate kinase activity
FFE90_015915	COG0205	6-phosphofructokinase activity
FFE90_015920	COG0825	malonyl-CoA metabolic process
FFE90_015925	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FFE90_015930	COG0281	malic enzyme
FFE90_015935	COG0587	DNA-directed DNA polymerase activity
FFE90_015955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FFE90_015965	COG4109	DRTGG domain
FFE90_015970	COG0730	response to heat
FFE90_015975	COG1473	amidohydrolase
FFE90_015980	COG0196	riboflavin kinase activity
FFE90_015985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE90_015990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE90_015995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE90_016000	COG1126	abc transporter atp-binding protein
FFE90_016005	COG0765	amino acid transport
FFE90_016010	COG0765	amino acid transport
FFE90_016015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE90_016020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE90_016025	COG0454	-acetyltransferase
FFE90_016030	COG0583	DNA-binding transcription factor activity
FFE90_016035	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FFE90_016040	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_016050	COG0165	Argininosuccinate lyase
FFE90_016055	COG0137	argininosuccinate synthase activity
FFE90_016060	COG0521	Mo-molybdopterin cofactor biosynthetic process
FFE90_016065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFE90_016075	COG0827	DNA restriction-modification system
FFE90_016080	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FFE90_016085	COG3874	Sporulation protein YtfJ
FFE90_016095	COG1714	RDD family
FFE90_016100	COG0616	signal peptide processing
FFE90_016105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFE90_016110	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FFE90_016115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFE90_016125	COG0301	tRNA thio-modification
FFE90_016130	COG1104	cysteine desulfurase activity
FFE90_016135	COG1114	Component of the transport system for branched-chain amino acids
FFE90_016140	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FFE90_016145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FFE90_016150	COG1309	transcriptional regulator
FFE90_016155	COG1956	GAF domain-containing protein
FFE90_016160	COG2203	Gaf domain
FFE90_016160	COG2199	diguanylate cyclase activity
FFE90_016170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFE90_016175	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFE90_016180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFE90_016185	COG0454	-acetyltransferase
FFE90_016190	COG0517	IMP dehydrogenase activity
FFE90_016195	COG0123	including yeast histone deacetylase and acetoin utilization protein
FFE90_016200	COG1360	Flagellar Motor Protein
FFE90_016205	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FFE90_016210	COG1609	Transcriptional regulator
FFE90_016215	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FFE90_016215	COG1605	Chorismate mutase
FFE90_016220	COG3118	belongs to the thioredoxin family
FFE90_016225	COG4980	gas vesicle protein
FFE90_016230	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FFE90_016235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFE90_016240	COG1674	ftsk spoiiie
FFE90_016245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE90_016250	COG4848	Belongs to the UPF0354 family
FFE90_016255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_016270	COG1363	Peptidase, m42
FFE90_016275	COG5584	Small secreted protein
FFE90_016280	COG0281	malic enzyme
FFE90_016285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_016290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFE90_016300	COG0510	thiamine kinase activity
FFE90_016305	COG1523	belongs to the glycosyl hydrolase 13 family
FFE90_016310	COG1597	lipid kinase activity
FFE90_016320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FFE90_016325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FFE90_016330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE90_016335	COG2252	PERMEase
FFE90_016340	COG4473	ABC transporter
FFE90_016345	COG1131	(ABC) transporter
FFE90_016350	COG1349	DNA-binding transcription factor activity
FFE90_016355	COG1187	pseudouridine synthase activity
FFE90_016360	COG2244	polysaccharide biosynthetic process
FFE90_016365	COG2081	HI0933 family
FFE90_016370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FFE90_016380	COG5578	integral membrane protein
FFE90_016385	COG0673	inositol 2-dehydrogenase activity
FFE90_016390	COG1653	transport
FFE90_016395	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FFE90_016400	COG4209	transmembrane transport
FFE90_016405	COG2207	Transcriptional regulator
FFE90_016410	COG1653	transport
FFE90_016415	COG0395	ABC-type sugar transport system, permease component
FFE90_016420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE90_016425	COG2124	cytochrome p450
FFE90_016430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FFE90_016435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FFE90_016440	COG0156	8-amino-7-oxononanoate synthase activity
FFE90_016445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FFE90_016450	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
FFE90_016455	COG1073	alpha beta
FFE90_016480	COG1486	melibiose metabolic process
FFE90_016485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE90_016490	COG0495	leucyl-tRNA aminoacylation
FFE90_016500	COG1366	Belongs to the anti-sigma-factor antagonist family
FFE90_016500	COG2202	Pas domain
FFE90_016505	COG2814	Major facilitator Superfamily
FFE90_016510	COG2433	Pfam Transposase IS66
FFE90_016515	COG0577	efflux transmembrane transporter activity
FFE90_016520	COG1136	(ABC) transporter
FFE90_016525	COG2205	protein histidine kinase activity
FFE90_016530	COG0745	RESPONSE REGULATOR receiver
FFE90_016535	COG0577	efflux transmembrane transporter activity
FFE90_016540	COG1136	(ABC) transporter
FFE90_016555	COG1131	(ABC) transporter
FFE90_016560	COG1725	Transcriptional regulator
FFE90_016575	COG1242	4 iron, 4 sulfur cluster binding
FFE90_016580	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FFE90_016590	COG2267	carboxylic ester hydrolase activity
FFE90_016595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FFE90_016600	COG1113	amino acid transport
FFE90_016605	COG0367	asparagine synthase
FFE90_016610	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFE90_016615	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FFE90_016625	COG1506	peptidase
FFE90_016630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FFE90_016635	COG1116	anion transmembrane transporter activity
FFE90_016640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFE90_016645	COG0494	nUDIX hydrolase
FFE90_016650	COG4824	toxin secretion phage lysis holin
FFE90_016655	COG0783	Belongs to the Dps family
FFE90_016670	COG1854	S-ribosylhomocysteine lyase activity
FFE90_016675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FFE90_016680	COG0288	reversible hydration of carbon dioxide
FFE90_016685	COG0254	rRNA binding
FFE90_016690	COG1271	oxidase subunit
FFE90_016695	COG1294	oxidase, subunit
FFE90_016705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE90_016710	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE90_016710	COG1321	iron dependent repressor
FFE90_016715	COG1121	(ABC) transporter
FFE90_016720	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFE90_016730	COG4948	Mandelate Racemase Muconate Lactonizing
FFE90_016735	COG0318	PFAM AMP-dependent synthetase and ligase
FFE90_016740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FFE90_016745	COG0596	Alpha beta hydrolase
FFE90_016750	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FFE90_016755	COG1169	isochorismate synthase
FFE90_016765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FFE90_016770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE90_016775	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FFE90_016780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE90_016785	COG0438	transferase activity, transferring glycosyl groups
FFE90_016795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFE90_016800	COG0438	transferase activity, transferring glycosyl groups
FFE90_016805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFE90_016810	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FFE90_016815	COG0058	SHG alpha-glucan phosphorylase activity
FFE90_016820	COG0297	glycogen (starch) synthase activity
FFE90_016825	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FFE90_016830	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FFE90_016835	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FFE90_016960	COG3859	Proton-coupled thiamine transporter YuaJ
FFE90_016965	COG1247	-acetyltransferase
FFE90_016970	COG2268	Band 7 protein
FFE90_016975	COG1585	Membrane protein implicated in regulation of membrane protease activity
FFE90_016980	COG2318	DinB family
FFE90_016990	COG1454	alcohol dehydrogenase
FFE90_017000	COG1510	regulation of RNA biosynthetic process
FFE90_017010	COG0569	domain protein
FFE90_017015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FFE90_017020	COG4682	membrane
FFE90_017025	COG1705	Flagellar rod assembly protein muramidase FlgJ
FFE90_017030	COG0477	Major facilitator Superfamily
FFE90_017035	COG5553	Cysteine dioxygenase type I
FFE90_017045	COG1968	undecaprenyl-diphosphatase activity
FFE90_017050	COG0628	permease
FFE90_017055	COG0673	inositol 2-dehydrogenase activity
FFE90_017060	COG4806	L-rhamnose isomerase
FFE90_017065	COG3254	rhamnose metabolic process
FFE90_017070	COG1070	Carbohydrate kinase
FFE90_017075	COG1349	DNA-binding transcription factor activity
FFE90_017080	COG3347	Dehydrogenase
FFE90_017080	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_017090	COG0840	transmembrane signaling receptor activity
FFE90_017095	COG0840	transmembrane signaling receptor activity
FFE90_017100	COG0840	transmembrane signaling receptor activity
FFE90_017105	COG0840	transmembrane signaling receptor activity
FFE90_017120	COG0432	Pfam Uncharacterised protein family UPF0047
FFE90_017130	COG0366	Alpha amylase catalytic
FFE90_017135	COG1253	flavin adenine dinucleotide binding
FFE90_017140	COG2738	Putative neutral zinc metallopeptidase
FFE90_017155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFE90_017170	COG0166	Belongs to the GPI family
FFE90_017175	COG1979	alcohol dehydrogenase
FFE90_017180	COG1979	alcohol dehydrogenase
FFE90_017185	COG2155	Conserved Protein
FFE90_017190	COG1098	S1 RNA binding domain
FFE90_017195	COG0436	Aminotransferase
FFE90_017200	COG1522	sequence-specific DNA binding
FFE90_017205	COG2267	carboxylic ester hydrolase activity
FFE90_017215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FFE90_017220	COG2205	protein histidine kinase activity
FFE90_017230	COG5018	Exonuclease
FFE90_017240	COG2814	Major facilitator Superfamily
FFE90_017245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE90_017250	COG3011	Protein conserved in bacteria
FFE90_017260	COG3290	protein histidine kinase activity
FFE90_017265	COG4565	transcriptional regulatory protein
FFE90_017290	COG3493	citrate carrier protein
FFE90_017300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFE90_017300	COG2111	Na H antiporter
FFE90_017305	COG2111	Na H antiporter
FFE90_017310	COG1006	Multisubunit Na H antiporter MnhC subunit
FFE90_017315	COG0651	ATP synthesis coupled electron transport
FFE90_017320	COG1863	multisubunit Na H antiporter MnhE subunit
FFE90_017325	COG2212	antiporter activity
FFE90_017330	COG1320	monovalent cation:proton antiporter activity
FFE90_017335	COG2050	protein possibly involved in aromatic compounds catabolism
FFE90_017340	COG2197	response regulator
FFE90_017345	COG4585	Histidine kinase
FFE90_017355	COG0142	geranyltranstransferase activity
FFE90_017375	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FFE90_017380	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FFE90_017385	COG1335	isochorismatase
FFE90_017390	COG5506	Protein of unknown function (DUF1694)
FFE90_017405	COG0628	permease
FFE90_017420	COG1418	mRNA catabolic process
FFE90_017425	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_017435	COG1511	domain protein
FFE90_017440	COG0433	COG0433 Predicted ATPase
FFE90_017440	COG1674	ftsk spoiiie
FFE90_017445	COG4499	WXG100 protein secretion system (Wss), protein YukC
FFE90_017450	COG5417	Belongs to the EsaB family
FFE90_017455	COG4842	Belongs to the WXG100 family
FFE90_017460	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FFE90_017460	COG2508	Transcriptional regulator
FFE90_017465	COG0686	Belongs to the AlaDH PNT family
FFE90_017470	COG5634	Uncharacterized conserved protein (DUF2278)
FFE90_017475	COG3251	PFAM MbtH domain protein
FFE90_017480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_017485	COG3433	isochorismatase activity
FFE90_017485	COG1535	isochorismatase
FFE90_017490	COG1021	2,3-dihydroxybenzoate-AMP ligase
FFE90_017495	COG1169	isochorismate synthase
FFE90_017500	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_017505	COG2819	hydrolase of the alpha beta superfamily
FFE90_017510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FFE90_017515	COG1268	BioY protein
FFE90_017520	COG2056	Na+-H+ antiporter family
FFE90_017525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFE90_017530	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FFE90_017535	COG3584	3D domain protein
FFE90_017550	COG1252	NADH dehydrogenase
FFE90_017555	COG0492	ferredoxin-NADP+ reductase activity
FFE90_017565	COG0516	GMP reductase activity
FFE90_017570	COG2808	Putative FMN-binding domain
FFE90_017575	COG0456	acetyltransferase
FFE90_017580	COG0316	Belongs to the HesB IscA family
FFE90_017585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FFE90_017590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE90_017595	COG4844	belongs to the
FFE90_017600	COG1252	NADH dehydrogenase
FFE90_017605	COG4837	Protein of unknown function (DUF1462)
FFE90_017610	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FFE90_017615	COG1506	peptidase
FFE90_017615	COG0823	Involved in the tonB-independent uptake of proteins
FFE90_017615	COG4946	Tricorn protease homolog
FFE90_017620	COG0083	homoserine kinase activity
FFE90_017625	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FFE90_017630	COG0460	homoserine dehydrogenase
FFE90_017635	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFE90_017640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FFE90_017645	COG0647	UMP catabolic process
FFE90_017650	COG2445	Protein of unknown function DUF86
FFE90_017655	COG4470	Protein conserved in bacteria
FFE90_017665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FFE90_017670	COG0739	heme binding
FFE90_017680	COG3377	Domain of unknown function (DUF1805)
FFE90_017685	COG0737	Belongs to the 5'-nucleotidase family
FFE90_017690	COG0730	response to heat
FFE90_017695	COG1801	Protein of unknown function DUF72
FFE90_017705	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FFE90_017710	COG2508	Transcriptional regulator
FFE90_017715	COG2233	PERMEase
FFE90_017720	COG2233	PERMEase
FFE90_017725	COG3195	allantoin biosynthetic process
FFE90_017725	COG3648	Uricase
FFE90_017730	COG2351	hydroxyisourate hydrolase activity
FFE90_017740	COG2080	2 iron, 2 sulfur cluster binding
FFE90_017745	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FFE90_017750	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FFE90_017755	COG2068	MobA-Related Protein
FFE90_017760	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FFE90_017765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FFE90_017770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE90_017780	COG2356	endonuclease I
FFE90_017785	COG3842	ATPase activity
FFE90_017790	COG2188	Transcriptional regulator
FFE90_017795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE90_017800	COG0395	ABC-type sugar transport system, permease component
FFE90_017805	COG1175	transmembrane transport
FFE90_017810	COG1653	transport
FFE90_017815	COG2222	sugar isomerase
FFE90_017820	COG0322	excinuclease ABC activity
FFE90_017825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFE90_017840	COG0346	lactoylglutathione lyase activity
FFE90_017845	COG0640	Transcriptional regulator
FFE90_017850	COG0719	Fe-S assembly protein
FFE90_017855	COG0822	iron-sulfur transferase activity
FFE90_017860	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FFE90_017865	COG0719	Fe-S assembly protein
FFE90_017870	COG0396	ATPase activity
FFE90_017885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE90_017890	COG1464	Belongs to the NlpA lipoprotein family
FFE90_017895	COG2011	ABC-type metal ion transport system permease component
FFE90_017900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFE90_017910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE90_017915	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FFE90_017925	COG0509	glycine decarboxylation via glycine cleavage system
FFE90_017930	COG1393	Belongs to the ArsC family
FFE90_017935	COG1960	acyl-CoA dehydrogenase activity
FFE90_017940	COG0183	Belongs to the thiolase family
FFE90_017945	COG1024	Enoyl-CoA hydratase
FFE90_017945	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFE90_017955	COG0506	proline dehydrogenase activity
FFE90_017965	COG5577	PFAM Coat F domain
FFE90_017970	COG1846	Transcriptional regulator
FFE90_017975	COG0477	Major facilitator Superfamily
FFE90_017980	COG1942	4-Oxalocrotonate Tautomerase
FFE90_017990	COG0583	DNA-binding transcription factor activity
FFE90_018000	COG1120	ATPase activity
FFE90_018015	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_018020	COG0783	Belongs to the Dps family
FFE90_018025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE90_018030	COG0745	RESPONSE REGULATOR receiver
FFE90_018035	COG2205	protein histidine kinase activity
FFE90_018035	COG2770	Histidine kinase
FFE90_018045	COG1309	transcriptional regulator
FFE90_018050	COG0114	fumarate hydratase activity
FFE90_018060	COG0697	spore germination
FFE90_018065	COG0814	amino acid
FFE90_018075	COG2197	response regulator
FFE90_018080	COG4585	Histidine kinase
FFE90_018085	COG4758	membrane
FFE90_018090	COG3595	metallopeptidase activity
FFE90_018095	COG1842	Phage shock protein A
FFE90_018100	COG4758	membrane
FFE90_018105	COG2814	Major facilitator Superfamily
FFE90_018110	COG2096	Adenosyltransferase
FFE90_018115	COG1120	ATPase activity
FFE90_018120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_018125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE90_018130	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_018135	COG3386	PFAM SMP-30 Gluconolaconase
FFE90_018140	COG2205	protein histidine kinase activity
FFE90_018145	COG0745	RESPONSE REGULATOR receiver
FFE90_018155	COG1191	sigma factor activity
FFE90_018165	COG2140	Oxalate decarboxylase
FFE90_018175	COG0577	efflux transmembrane transporter activity
FFE90_018180	COG1136	(ABC) transporter
FFE90_018185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE90_018190	COG1120	ATPase activity
FFE90_018195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_018200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE90_018205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE90_018215	COG0531	amino acid
FFE90_018230	COG1988	membrane-bound metal-dependent
FFE90_018235	COG1368	sulfuric ester hydrolase activity
FFE90_018240	COG1910	domain protein
FFE90_018245	COG0725	ABC transporter, periplasmic molybdate-binding protein
FFE90_018250	COG4149	molybdate abc transporter
FFE90_018255	COG0656	L-ascorbic acid biosynthetic process
FFE90_018265	COG0025	NhaP-type Na H and K H
FFE90_018270	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFE90_018275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FFE90_018280	COG3973	AAA domain
FFE90_018285	COG2860	membrane
FFE90_018290	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FFE90_018295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FFE90_018300	COG2217	Heavy metal translocating P-type atpase
FFE90_018305	COG2217	Heavy metal translocating P-type atpase
FFE90_018310	COG2608	mercury ion transmembrane transporter activity
FFE90_018315	COG1937	Protein conserved in bacteria
FFE90_018320	COG0673	inositol 2-dehydrogenase activity
FFE90_018325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FFE90_018330	COG1289	transmembrane transporter activity
FFE90_018340	COG2076	Multidrug Resistance protein
FFE90_018345	COG1309	transcriptional regulator
FFE90_018350	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_018360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FFE90_018365	COG0557	exoribonuclease II activity
FFE90_018370	COG1647	Serine aminopeptidase, S33
FFE90_018375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFE90_018380	COG0596	Alpha beta hydrolase
FFE90_018385	COG1476	TRANSCRIPTIONal
FFE90_018390	COG1396	sequence-specific DNA binding
FFE90_018395	COG1396	sequence-specific DNA binding
FFE90_018400	COG1733	regulation of RNA biosynthetic process
FFE90_018405	COG0840	transmembrane signaling receptor activity
FFE90_018410	COG1174	glycine betaine transport
FFE90_018415	COG1732	Glycine betaine
FFE90_018420	COG1174	glycine betaine transport
FFE90_018425	COG0517	IMP dehydrogenase activity
FFE90_018425	COG1125	glycine betaine transport
FFE90_018430	COG1510	regulation of RNA biosynthetic process
FFE90_018450	COG5658	integral membrane protein
FFE90_018455	COG0640	Transcriptional regulator
FFE90_018460	COG1174	glycine betaine transport
FFE90_018465	COG1732	Glycine betaine
FFE90_018470	COG1174	glycine betaine transport
FFE90_018475	COG1125	glycine betaine transport
FFE90_018475	COG0517	IMP dehydrogenase activity
FFE90_018480	COG1510	regulation of RNA biosynthetic process
FFE90_018485	COG2095	MarC family integral membrane protein
FFE90_018495	COG3064	Membrane
FFE90_018500	COG4640	response to antibiotic
FFE90_018505	COG0456	acetyltransferase
FFE90_018510	COG0148	phosphopyruvate hydratase activity
FFE90_018515	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FFE90_018520	COG0149	triose-phosphate isomerase activity
FFE90_018525	COG0126	phosphoglycerate kinase activity
FFE90_018530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FFE90_018535	COG2390	Transcriptional regulator
FFE90_018540	COG2814	Major facilitator Superfamily
FFE90_018545	COG1609	Transcriptional regulator
FFE90_018550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE90_018560	COG0583	DNA-binding transcription factor activity
FFE90_018565	COG0697	spore germination
FFE90_018570	COG1113	amino acid transport
FFE90_018575	COG3858	chitin binding
FFE90_018580	COG1556	Lactate utilization protein
FFE90_018585	COG1139	Iron-sulfur cluster binding protein
FFE90_018590	COG0247	lactate metabolic process
FFE90_018595	COG2197	response regulator
FFE90_018600	COG4585	Histidine kinase
FFE90_018605	COG0842	Transport permease protein
FFE90_018610	COG1131	(ABC) transporter
FFE90_018615	COG0596	Alpha beta hydrolase
FFE90_018620	COG2208	phosphoserine phosphatase activity
FFE90_018625	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FFE90_018630	COG1874	Beta-galactosidase
FFE90_018635	COG3833	ABC-type maltose transport systems, permease component
FFE90_018640	COG1175	transmembrane transport
FFE90_018645	COG2182	Extracellular solute-binding protein
FFE90_018650	COG1609	Transcriptional regulator
FFE90_018655	COG2186	Transcriptional regulator
FFE90_018660	COG1620	l-lactate permease
FFE90_018665	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FFE90_018675	COG5039	Polysaccharide pyruvyl transferase
FFE90_018680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFE90_018685	COG0110	maltose O-acetyltransferase activity
FFE90_018690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FFE90_018695	COG2244	polysaccharide biosynthetic process
FFE90_018700	COG1216	Glycosyl transferase, family 2
FFE90_018705	COG5039	Polysaccharide pyruvyl transferase
FFE90_018710	COG1216	Glycosyl transferase, family 2
FFE90_018720	COG0438	transferase activity, transferring glycosyl groups
FFE90_018725	COG1215	transferase activity, transferring glycosyl groups
FFE90_018730	COG0438	transferase activity, transferring glycosyl groups
FFE90_018735	COG1086	Polysaccharide biosynthesis protein
FFE90_018740	COG0489	protein tyrosine kinase activity
FFE90_018745	COG3944	biosynthesis protein
FFE90_018750	COG1396	sequence-specific DNA binding
FFE90_018755	COG2272	Belongs to the type-B carboxylesterase lipase family
FFE90_018765	COG3479	Phenolic acid decarboxylase
FFE90_018775	COG1794	racemase activity, acting on amino acids and derivatives
FFE90_018780	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FFE90_018785	COG1621	beta-fructofuranosidase activity
FFE90_018790	COG1621	beta-fructofuranosidase activity
FFE90_018795	COG0531	amino acid
FFE90_018800	COG1309	transcriptional regulator
FFE90_018805	COG2076	Multidrug Resistance protein
FFE90_018810	COG2076	Multidrug Resistance protein
FFE90_018820	COG0277	FAD linked oxidase domain protein
FFE90_018825	COG3621	Patatin-like phospholipase
FFE90_018835	COG0740	serine-type endopeptidase activity
FFE90_018840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE90_018845	COG0366	Alpha amylase catalytic
FFE90_018850	COG1554	hydrolase, family 65, central catalytic
FFE90_018855	COG5521	maltodextrose utilization protein MalA
FFE90_018860	COG3833	ABC-type maltose transport systems, permease component
FFE90_018865	COG1175	transmembrane transport
FFE90_018870	COG2182	Extracellular solute-binding protein
FFE90_018875	COG0366	Alpha amylase catalytic
FFE90_018880	COG1609	Transcriptional regulator
FFE90_018885	COG1611	Belongs to the LOG family
FFE90_018890	COG1694	Mazg nucleotide pyrophosphohydrolase
FFE90_018895	COG0659	secondary active sulfate transmembrane transporter activity
FFE90_018900	COG0288	reversible hydration of carbon dioxide
FFE90_018910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFE90_018915	COG0577	efflux transmembrane transporter activity
FFE90_018920	COG1136	(ABC) transporter
FFE90_018925	COG5002	protein histidine kinase activity
FFE90_018930	COG0745	RESPONSE REGULATOR receiver
FFE90_018940	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FFE90_018945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_018950	COG1481	regulation of sporulation
FFE90_018955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FFE90_018960	COG1660	Displays ATPase and GTPase activities
FFE90_018965	COG1051	belongs to the nudix hydrolase family
FFE90_018970	COG0492	ferredoxin-NADP+ reductase activity
FFE90_018975	COG3883	PFAM NLP P60 protein
FFE90_018975	COG0791	NLP P60 protein
FFE90_018980	COG0457	Tetratricopeptide repeat
FFE90_018985	COG1132	(ABC) transporter
FFE90_019005	COG0140	phosphoribosyl-ATP diphosphatase activity
FFE90_019005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FFE90_019010	COG0107	imidazoleglycerol-phosphate synthase activity
FFE90_019015	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FFE90_019020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FFE90_019025	COG0131	Imidazoleglycerol-phosphate dehydratase
FFE90_019030	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FFE90_019035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FFE90_019040	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FFE90_019045	COG4990	cell redox homeostasis
FFE90_019050	COG5297	Belongs to the glycosyl hydrolase family 6
FFE90_019055	COG0110	maltose O-acetyltransferase activity
FFE90_019060	COG0546	phosphoglycolate phosphatase activity
FFE90_019065	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FFE90_019070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FFE90_019075	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FFE90_019080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FFE90_019085	COG0363	glucosamine-6-phosphate deaminase activity
FFE90_019095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FFE90_019100	COG1846	Transcriptional regulator
FFE90_019105	COG2124	cytochrome p450
FFE90_019115	COG1846	Transcriptional regulator
FFE90_019120	COG2814	Major facilitator Superfamily
FFE90_019125	COG1950	PFAM Membrane protein of
FFE90_019130	COG1983	PspC domain protein
FFE90_019135	COG3595	metallopeptidase activity
FFE90_019155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FFE90_019160	COG0556	nucleotide-excision repair
FFE90_019165	COG4897	Protein conserved in bacteria
FFE90_019170	COG0574	Belongs to the PEP-utilizing enzyme family
FFE90_019170	COG3848	Pyruvate phosphate dikinase
FFE90_019175	COG1309	transcriptional regulator
FFE90_019180	COG2814	Major facilitator Superfamily
FFE90_019185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE90_019195	COG3409	Peptidoglycan-binding domain 1 protein
FFE90_019195	COG0793	Belongs to the peptidase S41A family
FFE90_019200	COG2177	Part of the ABC transporter FtsEX involved in
FFE90_019205	COG2884	Cell division ATP-binding protein ftsE
FFE90_019210	COG2010	Cytochrome c
FFE90_019215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFE90_019225	COG0653	protein targeting
FFE90_019230	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FFE90_019245	COG1516	flagellar protein fliS
FFE90_019250	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FFE90_019255	COG1334	flagellar protein FlaG
FFE90_019260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFE90_019265	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FFE90_019270	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FFE90_019280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFE90_019285	COG4786	Flagellar basal body rod
FFE90_019285	COG1256	bacterial-type flagellum assembly
FFE90_019290	COG3418	PFAM FlgN family protein
FFE90_019295	COG2747	anti-sigma28 factor FlgM
FFE90_019305	COG1040	competence protein
FFE90_019315	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FFE90_019320	COG1307	EDD domain protein, DegV family
FFE90_019325	COG2197	response regulator
FFE90_019330	COG4585	Histidine kinase
FFE90_019335	COG1739	Uncharacterized protein family UPF0029
FFE90_019340	COG1316	TRANSCRIPTIONal
FFE90_019345	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFE90_019350	COG0438	transferase activity, transferring glycosyl groups
FFE90_019355	COG1215	transferase activity, transferring glycosyl groups
FFE90_019360	COG3206	protein involved in exopolysaccharide biosynthesis
FFE90_019365	COG3307	-O-antigen
FFE90_019370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FFE90_019375	COG0297	glycogen (starch) synthase activity
FFE90_019375	COG0438	transferase activity, transferring glycosyl groups
FFE90_019380	COG2244	polysaccharide biosynthetic process
FFE90_019390	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE90_019390	COG2247	cell wall binding repeat
FFE90_019395	COG2385	sporulation resulting in formation of a cellular spore
FFE90_019395	COG2247	cell wall binding repeat
FFE90_019405	COG1316	TRANSCRIPTIONal
FFE90_019410	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFE90_019415	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE90_019425	COG1215	transferase activity, transferring glycosyl groups
FFE90_019425	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FFE90_019430	COG0463	Glycosyl transferase, family 2
FFE90_019440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FFE90_019450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE90_019455	COG1134	teichoic acid transport
FFE90_019460	COG1682	transport, permease protein
FFE90_019465	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FFE90_019470	COG0438	transferase activity, transferring glycosyl groups
FFE90_019475	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FFE90_019480	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FFE90_019485	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FFE90_019495	COG4193	domain, Protein
FFE90_019500	COG1482	cell wall glycoprotein biosynthetic process
FFE90_019505	COG0697	spore germination
FFE90_019510	COG0814	amino acid
FFE90_019520	COG2814	Major facilitator Superfamily
FFE90_019525	COG1316	TRANSCRIPTIONal
FFE90_019530	COG0561	phosphatase activity
FFE90_019535	COG0791	NLP P60 protein
FFE90_019545	COG2843	Capsule synthesis protein
FFE90_019555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FFE90_019565	COG1609	Transcriptional regulator
FFE90_019570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE90_019575	COG1869	D-ribose catabolic process
FFE90_019580	COG1129	ABC transporter
FFE90_019585	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE90_019590	COG1879	ABC-type sugar transport system periplasmic component
FFE90_019595	COG3103	Sh3 type 3 domain protein
FFE90_019605	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFE90_019610	COG3527	Alpha-acetolactate decarboxylase
FFE90_019615	COG0028	Belongs to the TPP enzyme family
FFE90_019620	COG0583	DNA-binding transcription factor activity
FFE90_019625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FFE90_019640	COG5337	Spore coat protein CotH
FFE90_019650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FFE90_019660	COG0405	Gamma-glutamyltransferase
FFE90_019665	COG1522	sequence-specific DNA binding
FFE90_019670	COG2059	Chromate
FFE90_019675	COG2059	Chromate
FFE90_019685	COG0655	NAD(P)H dehydrogenase (quinone) activity
FFE90_019690	COG0583	DNA-binding transcription factor activity
FFE90_019695	COG1515	deoxyribonuclease V activity
FFE90_019700	COG2849	repeat protein
FFE90_019705	COG5444	nuclease activity
FFE90_019725	COG3878	Protein conserved in bacteria
FFE90_019730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FFE90_019735	COG4464	protein tyrosine phosphatase activity
FFE90_019740	COG0489	protein tyrosine kinase activity
FFE90_019745	COG3944	biosynthesis protein
FFE90_019755	COG4715	Zinc finger, swim domain protein
FFE90_019760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FFE90_019770	COG0561	phosphatase activity
FFE90_019775	COG1349	DNA-binding transcription factor activity
FFE90_019780	COG0629	single-stranded DNA binding
FFE90_019795	COG3764	Sortase (surface protein transpeptidase)
FFE90_019805	COG0745	RESPONSE REGULATOR receiver
FFE90_019805	COG2972	Histidine kinase
FFE90_019810	COG1970	mechanosensitive ion channel activity
FFE90_019815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFE90_019820	COG0457	Tetratricopeptide repeat
FFE90_019825	COG4786	Flagellar basal body rod
FFE90_019830	COG4786	Flagellar basal body rod
FFE90_019835	COG1077	Cell shape determining protein MreB Mrl
FFE90_019840	COG1609	Transcriptional regulator
FFE90_019850	COG1846	Transcriptional regulator
FFE90_019855	COG2814	Major facilitator Superfamily
FFE90_019860	COG3420	alginic acid biosynthetic process
FFE90_019865	COG1953	Uracil, thiamine, allantoin
FFE90_019870	COG0477	Major facilitator Superfamily
FFE90_019875	COG1335	isochorismatase
FFE90_019885	COG0004	ammonium transporteR
FFE90_019890	COG0347	Belongs to the P(II) protein family
FFE90_019895	COG0671	phosphoesterase, PA-phosphatase related
FFE90_019905	COG0739	heme binding
FFE90_019910	COG1247	-acetyltransferase
FFE90_019930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFE90_019935	COG0789	Transcriptional regulator
FFE90_019945	COG2910	NAD(P)H-binding
FFE90_019950	COG1959	2 iron, 2 sulfur cluster binding
FFE90_019955	COG0804	urea catabolic process
FFE90_019960	COG0832	Belongs to the urease beta subunit family
FFE90_019965	COG0831	urea catabolic process
FFE90_019980	COG3237	CsbD-like
FFE90_019985	COG1994	Peptidase M50
FFE90_019990	COG0457	Tetratricopeptide repeat
FFE90_019995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFE90_020000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FFE90_020010	COG2304	oxidoreductase activity
FFE90_020020	COG2304	oxidoreductase activity
FFE90_020025	COG2385	sporulation resulting in formation of a cellular spore
FFE90_020030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FFE90_020040	COG4836	Membrane
FFE90_020050	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FFE90_020055	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FFE90_020060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FFE90_020065	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FFE90_020070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFE90_020075	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FFE90_020080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFE90_020085	COG0356	it plays a direct role in the translocation of protons across the membrane
FFE90_020095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FFE90_020100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FFE90_020105	COG4475	Protein of unknown function (DUF436)
FFE90_020110	COG0698	ribose 5-phosphate isomerase
FFE90_020115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FFE90_020120	COG1971	Probably functions as a manganese efflux pump
FFE90_020125	COG0009	L-threonylcarbamoyladenylate synthase
FFE90_020130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FFE90_020150	COG2890	protein-(glutamine-N5) methyltransferase activity
FFE90_020155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FFE90_020160	COG0346	lactoylglutathione lyase activity
FFE90_020165	COG0789	Transcriptional regulator
FFE90_020170	COG0679	Auxin Efflux Carrier
FFE90_020175	COG0281	malic enzyme
FFE90_020180	COG1435	thymidine kinase activity
FFE90_020185	COG0254	rRNA binding
FFE90_020190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FFE90_020200	COG1494	fructose-1,6-bisphosphatase
FFE90_020205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FFE90_020210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFE90_020215	COG0191	fructose-bisphosphate aldolase activity
FFE90_020220	COG2204	response regulator
FFE90_020225	COG4821	SIS domain
FFE90_020230	COG0504	CTP synthase activity
FFE90_020235	COG3343	RNA polymerase activity
FFE90_020240	COG1960	acyl-CoA dehydrogenase activity
FFE90_020245	COG2181	nitrate reductase activity
FFE90_020245	COG0247	lactate metabolic process
FFE90_020250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFE90_020255	COG4294	response to UV
FFE90_020265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFE90_020270	COG1132	(ABC) transporter
FFE90_020275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFE90_020285	COG2181	nitrate reductase activity
FFE90_020290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FFE90_020295	COG1140	nitrate reductase beta subunit
FFE90_020300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FFE90_020305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFE90_020315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFE90_020320	COG2223	nitrite transmembrane transporter activity
FFE90_020325	COG0018	arginyl-trna synthetase
FFE90_020330	COG4506	Protein conserved in bacteria
FFE90_020345	COG0535	radical SAM domain protein
FFE90_020355	COG1131	(ABC) transporter
FFE90_020360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FFE90_020365	COG0612	Peptidase, M16
FFE90_020370	COG0612	Peptidase, M16
FFE90_020380	COG3391	amine dehydrogenase activity
FFE90_020385	COG3391	amine dehydrogenase activity
FFE90_020395	COG0457	Tetratricopeptide repeat
FFE90_020405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FFE90_020410	COG0010	Belongs to the arginase family
FFE90_020415	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FFE90_020420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE90_020435	COG1994	Peptidase M50
FFE90_020440	COG1942	4-Oxalocrotonate Tautomerase
FFE90_020445	COG1846	Transcriptional regulator
FFE90_020450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FFE90_020460	COG0477	Major facilitator Superfamily
FFE90_020465	COG1959	2 iron, 2 sulfur cluster binding
FFE90_020470	COG3465	dGTPase activity
FFE90_020475	COG1078	dGTPase activity
FFE90_020480	COG4844	belongs to the
FFE90_020490	COG0697	spore germination
FFE90_020495	COG0095	Lipoate-protein ligase
FFE90_020500	COG0583	DNA-binding transcription factor activity
FFE90_020505	COG0280	phosphate acetyltransferase
FFE90_020515	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_020520	COG0436	Aminotransferase
FFE90_020525	COG2814	Major facilitator Superfamily
FFE90_020530	COG0151	Belongs to the GarS family
FFE90_020535	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_020540	COG1917	Cupin 2, conserved barrel domain protein
FFE90_020545	COG0077	Prephenate dehydratase
FFE90_020550	COG2814	Major facilitator Superfamily
FFE90_020555	COG0833	amino acid
FFE90_020560	COG4187	Peptidase family M20/M25/M40
FFE90_020565	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_020570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FFE90_020580	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FFE90_020585	COG1091	dTDP-4-dehydrorhamnose reductase activity
FFE90_020590	COG1088	dTDP-glucose 4,6-dehydratase activity
FFE90_020595	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FFE90_020600	COG3980	spore coat polysaccharide biosynthesis protein
FFE90_020605	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FFE90_020610	COG2089	acid synthase
FFE90_020615	COG0456	acetyltransferase
FFE90_020620	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFE90_020625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FFE90_020630	COG0463	Glycosyl transferase, family 2
FFE90_020645	COG2363	Small membrane protein
FFE90_020650	COG2233	PERMEase
FFE90_020660	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_020665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FFE90_020670	COG1216	Glycosyl transferase, family 2
FFE90_020685	COG1695	Transcriptional regulator
FFE90_020690	COG0351	phosphomethylpyrimidine kinase
FFE90_020700	COG1621	beta-fructofuranosidase activity
FFE90_020705	COG1263	PTS System
FFE90_020705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_020710	COG2116	formate transmembrane transporter activity
FFE90_020715	COG3711	transcriptional antiterminator
FFE90_020725	COG1404	Belongs to the peptidase S8 family
FFE90_020730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE90_020735	COG0778	Nitroreductase
FFE90_020740	COG0772	Belongs to the SEDS family
FFE90_020750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FFE90_020755	COG1845	cytochrome c oxidase, subunit III
FFE90_020760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFE90_020765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFE90_020770	COG2261	transglycosylase associated protein
FFE90_020775	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FFE90_020780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FFE90_020785	COG2246	polysaccharide biosynthetic process
FFE90_020790	COG1309	transcriptional regulator
FFE90_020800	COG3162	membrane
FFE90_020805	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE90_020810	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FFE90_020815	COG2837	iron assimilation
FFE90_020820	COG2822	iron ion transport
FFE90_020825	COG0672	)-iron permease
FFE90_020830	COG0352	thiamine-phosphate diphosphorylase activity
FFE90_020835	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FFE90_020840	COG0583	DNA-binding transcription factor activity
FFE90_020845	COG1380	Effector of murein hydrolase LrgA
FFE90_020850	COG1346	cytolysis
FFE90_020855	COG2814	Major facilitator Superfamily
FFE90_020860	COG4895	conserved protein (DUF2196)
FFE90_020865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FFE90_020870	COG0346	lactoylglutathione lyase activity
FFE90_020880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE90_020885	COG1404	Belongs to the peptidase S8 family
FFE90_020890	COG1263	PTS System
FFE90_020890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_020895	COG3711	transcriptional antiterminator
FFE90_020900	COG1442	glycosyl transferase family 8
FFE90_020905	COG5522	Integral membrane protein (intg_mem_TP0381)
FFE90_020910	COG1846	Transcriptional regulator
FFE90_020915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFE90_020920	COG2234	aminopeptidase activity
FFE90_020925	COG2357	RelA SpoT domain protein
FFE90_020930	COG1575	Belongs to the MenA family. Type 1 subfamily
FFE90_020950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FFE90_020955	COG1696	Membrane protein involved in D-alanine export
FFE90_020960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FFE90_020965	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FFE90_020970	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FFE90_020975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE90_020980	COG1486	melibiose metabolic process
FFE90_020985	COG1447	Phosphotransferase system cellobiose-specific component IIA
FFE90_020990	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE90_020995	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE90_021000	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE90_021000	COG3711	transcriptional antiterminator
FFE90_021010	COG2094	Belongs to the DNA glycosylase MPG family
FFE90_021015	COG0753	catalase activity
FFE90_021020	COG2814	Major facilitator Superfamily
FFE90_021025	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FFE90_021030	COG1131	(ABC) transporter
FFE90_021050	COG1595	DNA-templated transcription, initiation
FFE90_021055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FFE90_021060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FFE90_021065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FFE90_021070	COG4988	ABC transporter
FFE90_021075	COG1294	oxidase, subunit
FFE90_021080	COG1271	oxidase subunit
FFE90_021085	COG3493	citrate carrier protein
FFE90_021090	COG0501	Belongs to the peptidase M48B family
FFE90_021100	COG0726	polysaccharide deacetylase
FFE90_021105	COG3842	ATPase activity
FFE90_021110	COG2508	Transcriptional regulator
FFE90_021115	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_021120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FFE90_021130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FFE90_021135	COG1881	PFAM PEBP family protein
FFE90_021140	COG0583	DNA-binding transcription factor activity
FFE90_021150	COG4585	Histidine kinase
FFE90_021155	COG2197	response regulator
FFE90_021160	COG2195	Cleaves the N-terminal amino acid of tripeptides
FFE90_021170	COG4894	glucomannan catabolic process
FFE90_021175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FFE90_021180	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FFE90_021185	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_021190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FFE90_021195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FFE90_021200	COG2610	gluconate transmembrane transporter activity
FFE90_021205	COG0500	methyltransferase
FFE90_021210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE90_021225	COG0753	catalase activity
FFE90_021225	COG0693	protein deglycase activity
FFE90_021230	COG2851	Citrate transporter
FFE90_021235	COG2273	Hydrolase Family 16
FFE90_021240	COG3711	transcriptional antiterminator
FFE90_021250	COG2270	Major facilitator Superfamily
FFE90_021255	COG0513	Belongs to the DEAD box helicase family
FFE90_021260	COG2755	lipolytic protein G-D-S-L family
FFE90_021260	COG3401	FG-GAP repeat protein
FFE90_021315	COG3209	COG3209 Rhs family protein
FFE90_021320	COG0697	spore germination
FFE90_021325	COG0589	response to stress
FFE90_021330	COG2723	6-phospho-beta-galactosidase activity
FFE90_021335	COG1263	PTS System
FFE90_021335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_021335	COG2190	(PTS) system
FFE90_021350	COG5444	nuclease activity
FFE90_021365	COG3507	Belongs to the glycosyl hydrolase 43 family
FFE90_021380	COG2986	histidine ammonia-lyase
FFE90_021385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FFE90_021390	COG1228	amidohydrolase
FFE90_021395	COG0010	Belongs to the arginase family
FFE90_021400	COG0833	amino acid
FFE90_021405	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FFE90_021410	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE90_021415	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FFE90_021420	COG2390	Transcriptional regulator
FFE90_021430	COG3192	ethanolamine utilization protein
FFE90_021435	COG2079	MmgE PrpD family protein
FFE90_021445	COG1126	abc transporter atp-binding protein
FFE90_021450	COG0765	amino acid transport
FFE90_021455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE90_021475	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FFE90_021480	COG0561	phosphatase activity
FFE90_021510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE90_021515	COG5294	Protein conserved in bacteria
FFE90_021520	COG0577	efflux transmembrane transporter activity
FFE90_021525	COG1136	(ABC) transporter
FFE90_021530	COG2205	protein histidine kinase activity
FFE90_021535	COG0745	RESPONSE REGULATOR receiver
FFE90_021540	COG0191	fructose-bisphosphate aldolase activity
FFE90_021545	COG1082	Xylose isomerase domain protein TIM barrel
FFE90_021550	COG1082	Xylose isomerase domain protein TIM barrel
FFE90_021555	COG0673	inositol 2-dehydrogenase activity
FFE90_021560	COG2814	Major facilitator Superfamily
FFE90_021565	COG1082	Xylose isomerase domain protein TIM barrel
FFE90_021570	COG3962	Belongs to the TPP enzyme family
FFE90_021575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE90_021580	COG3718	enzyme involved in inositol metabolism
FFE90_021585	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_021590	COG1349	DNA-binding transcription factor activity
FFE90_021595	COG0667	Aldo Keto reductase
FFE90_021610	COG2814	Major facilitator Superfamily
FFE90_021615	COG0326	Molecular chaperone. Has ATPase activity
FFE90_021625	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_021630	COG1309	transcriptional regulator
FFE90_021635	COG1012	belongs to the aldehyde dehydrogenase family
FFE90_021640	COG0456	acetyltransferase
FFE90_021645	COG2850	peptidyl-arginine hydroxylation
FFE90_021650	COG2226	methyltransferase
FFE90_021665	COG0367	asparagine synthase
FFE90_021670	COG2814	Major facilitator Superfamily
FFE90_021675	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFE90_021685	COG1714	RDD family
FFE90_021690	COG2311	Membrane
FFE90_021695	COG1917	Cupin 2, conserved barrel domain protein
FFE90_021700	COG1309	transcriptional regulator
FFE90_021705	COG1028	Short-chain dehydrogenase reductase Sdr
FFE90_021710	COG1846	Transcriptional regulator
FFE90_021715	COG1380	Effector of murein hydrolase LrgA
FFE90_021720	COG1346	cytolysis
FFE90_021725	COG5039	Polysaccharide pyruvyl transferase
FFE90_021730	COG1929	Belongs to the glycerate kinase type-1 family
FFE90_021735	COG1802	Transcriptional regulator
FFE90_021740	COG1070	Carbohydrate kinase
FFE90_021745	COG2610	gluconate transmembrane transporter activity
FFE90_021750	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FFE90_021755	COG0450	alkyl hydroperoxide reductase
FFE90_021760	COG3634	alkyl hydroperoxide reductase activity
FFE90_021765	COG2723	6-phospho-beta-galactosidase activity
FFE90_021770	COG2190	(PTS) system
FFE90_021775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE90_021775	COG2190	(PTS) system
FFE90_021775	COG1263	PTS System
FFE90_021780	COG2188	Transcriptional regulator
FFE90_021795	COG1131	(ABC) transporter
FFE90_021800	COG1994	Peptidase M50
FFE90_021805	COG0535	radical SAM domain protein
FFE90_021815	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FFE90_021820	COG5293	efflux transmembrane transporter activity
FFE90_021830	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FFE90_021835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FFE90_021850	COG1063	alcohol dehydrogenase
FFE90_021870	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FFE90_021875	COG0456	acetyltransferase
FFE90_021880	COG0457	Tetratricopeptide repeat
FFE90_021890	COG0010	Belongs to the arginase family
FFE90_021895	COG0833	amino acid
FFE90_021900	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFE90_021905	COG3829	transcription factor binding
FFE90_021925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE90_021930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FFE90_021935	COG4853	Protein conserved in bacteria
FFE90_021940	COG4863	YycH protein
FFE90_021945	COG5002	protein histidine kinase activity
FFE90_021950	COG0745	RESPONSE REGULATOR receiver
FFE90_021980	COG0346	lactoylglutathione lyase activity
FFE90_021985	COG0305	Participates in initiation and elongation during chromosome replication
FFE90_022000	COG3093	addiction module antidote protein HigA
FFE90_022005	COG2807	transmembrane transport
FFE90_022010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFE90_022015	COG0359	binds to the 23S rRNA
FFE90_022020	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FFE90_022025	COG4241	membrane
FFE90_022035	COG5577	PFAM Coat F domain
FFE90_022040	COG1733	regulation of RNA biosynthetic process
FFE90_022045	COG1227	inorganic diphosphatase activity
FFE90_022060	COG2271	Major facilitator Superfamily
FFE90_022095	COG1131	(ABC) transporter
FFE90_022110	COG4319	ketosteroid isomerase
FFE90_022115	COG1357	PFAM Pentapeptide repeats (8 copies)
FFE90_022120	COG2814	Major facilitator Superfamily
FFE90_022125	COG0583	DNA-binding transcription factor activity
FFE90_022130	COG2153	protein acetylation
FFE90_022145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE90_022150	COG1846	Transcriptional regulator
FFE90_022155	COG2153	protein acetylation
FFE90_022160	COG2364	Membrane
FFE90_022165	COG0456	acetyltransferase
FFE90_022170	COG2315	Protein conserved in bacteria
FFE90_022175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFE90_022185	COG2814	Major facilitator Superfamily
FFE90_022195	COG1331	Highly conserved protein containing a thioredoxin domain
FFE90_022200	COG0789	Transcriptional regulator
FFE90_022205	COG0697	spore germination
FFE90_022210	COG1331	Highly conserved protein containing a thioredoxin domain
FFE90_022215	COG1266	CAAX protease self-immunity
FFE90_022220	COG0477	Major facilitator Superfamily
FFE90_022220	COG2814	Major facilitator Superfamily
FFE90_022225	COG0110	maltose O-acetyltransferase activity
FFE90_022230	COG0346	lactoylglutathione lyase activity
FFE90_022235	COG1609	Transcriptional regulator
FFE90_022240	COG0708	Exodeoxyribonuclease III
FFE90_022245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FFE90_022250	COG0629	single-stranded DNA binding
FFE90_022255	COG0360	Binds together with S18 to 16S ribosomal RNA
FFE90_022260	COG0012	GTP binding
FFE90_022265	COG0243	molybdopterin cofactor binding
FFE90_022270	COG4481	Protein conserved in bacteria
FFE90_022275	COG3949	Membrane
FFE90_022285	COG1475	DNA binding
FFE90_022290	COG1192	Involved in chromosome partitioning
FFE90_022300	COG1475	DNA binding
FFE90_022305	COG0357	Ribosomal RNA small subunit methyltransferase G
FFE90_022310	COG0445	tRNA wobble uridine modification
FFE90_022315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FFE90_022320	COG1847	R3H domain protein
FFE90_022325	COG0706	membrane insertase activity
FFE90_022330	COG0594	ribonuclease P activity
FFE90_022335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FFE90_022345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE90_022350	COG0716	FMN binding
FFE90_022390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFE90_022425	COG0328	RNA-DNA hybrid ribonuclease activity
FFE90_022445	COG0587	DNA-directed DNA polymerase activity
FFE90_022465	COG0194	GDP metabolic process
FFE90_022510	COG0187	DNA topoisomerase II activity
FFE90_022515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FFE90_022570	COG5444	nuclease activity
FFE90_022625	COG3953	SLT domain
FFE90_022625	COG5280	Phage tail tape measure protein TP901
FFE90_022715	COG0457	Tetratricopeptide repeat
FFE90_022735	COG1388	LysM domain
FFE90_022735	COG3584	3D domain protein
FFE90_022745	COG0582	viral genome integration into host DNA
FFE90_022815	COG2887	Belongs to the helicase family. UvrD subfamily