locus-tag	class	description
KH172YL63_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KH172YL63_00020	COG0592	DNA-directed DNA polymerase activity
KH172YL63_00030	COG2501	S4 domain
KH172YL63_00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KH172YL63_00060	COG0187	DNA topoisomerase II activity
KH172YL63_00070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KH172YL63_00090	COG0386	Belongs to the glutathione peroxidase family
KH172YL63_00110	COG0517	IMP dehydrogenase activity
KH172YL63_00110	COG0516	GMP reductase activity
KH172YL63_00140	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KH172YL63_00170	COG1428	Deoxynucleoside kinase
KH172YL63_00180	COG1428	Deoxynucleoside kinase
KH172YL63_00190	COG3858	chitin binding
KH172YL63_00190	COG1388	LysM domain
KH172YL63_00200	COG1335	isochorismatase
KH172YL63_00210	COG0590	tRNA wobble adenosine to inosine editing
KH172YL63_00220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KH172YL63_00230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KH172YL63_00240	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KH172YL63_00310	COG1982	Orn Lys Arg decarboxylase major
KH172YL63_00330	COG3870	Protein conserved in bacteria
KH172YL63_00340	COG1728	Protein conserved in bacteria
KH172YL63_00350	COG0470	DNA polymerase III
KH172YL63_00360	COG1774	PSP1 C-terminal conserved region
KH172YL63_00370	COG4467	Involved in initiation control of chromosome replication
KH172YL63_00380	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KH172YL63_00390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KH172YL63_00400	COG2002	toxin-antitoxin pair type II binding
KH172YL63_00420	COG0084	hydrolase, TatD family'
KH172YL63_00430	COG3583	domain protein
KH172YL63_00430	COG3584	3D domain protein
KH172YL63_00470	COG4466	Protein conserved in bacteria
KH172YL63_00490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KH172YL63_00500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KH172YL63_00510	COG0251	oxidation-reduction process
KH172YL63_00530	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KH172YL63_00550	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KH172YL63_00580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KH172YL63_00590	COG2002	toxin-antitoxin pair type II binding
KH172YL63_00600	COG2244	polysaccharide biosynthetic process
KH172YL63_00610	COG3956	TIGRFAM MazG family protein
KH172YL63_00620	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KH172YL63_00650	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KH172YL63_00660	COG1098	S1 RNA binding domain
KH172YL63_00680	COG2208	phosphoserine phosphatase activity
KH172YL63_00690	COG2304	oxidoreductase activity
KH172YL63_00700	COG0515	serine threonine protein kinase
KH172YL63_00710	COG0037	tRNA processing
KH172YL63_00730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KH172YL63_00760	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KH172YL63_00770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KH172YL63_00780	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KH172YL63_00790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KH172YL63_00800	COG0512	Glutamine amidotransferase of anthranilate synthase
KH172YL63_00810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KH172YL63_00820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KH172YL63_00830	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KH172YL63_00840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KH172YL63_00850	COG1396	sequence-specific DNA binding
KH172YL63_00870	COG3344	reverse transcriptase
KH172YL63_00900	COG3880	PFAM UvrB UvrC protein
KH172YL63_00910	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KH172YL63_00920	COG0542	response to heat
KH172YL63_00930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KH172YL63_00940	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KH172YL63_00950	COG4956	integral membrane protein (PIN domain superfamily)
KH172YL63_00970	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KH172YL63_00980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KH172YL63_00990	COG1045	serine acetyltransferase
KH172YL63_01000	COG0215	cysteine-tRNA ligase activity
KH172YL63_01020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KH172YL63_01030	COG3688	RNA-binding protein containing a PIN domain
KH172YL63_01050	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KH172YL63_01060	COG0250	Participates in transcription elongation, termination and antitermination
KH172YL63_01070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KH172YL63_01080	COG0081	regulation of translation
KH172YL63_01100	COG0222	ribosome binding
KH172YL63_01110	COG2813	Specifically methylates the guanine in position
KH172YL63_01140	COG1358	cellular component organization or biogenesis
KH172YL63_01160	COG0049	tRNA binding
KH172YL63_01170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KH172YL63_01180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KH172YL63_01200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KH172YL63_01210	COG0088	Forms part of the polypeptide exit tunnel
KH172YL63_01230	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KH172YL63_01240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KH172YL63_01250	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KH172YL63_01260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KH172YL63_01280	COG0255	Belongs to the universal ribosomal protein uL29 family
KH172YL63_01290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KH172YL63_01300	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KH172YL63_01330	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KH172YL63_01350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KH172YL63_01360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KH172YL63_01370	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KH172YL63_01380	COG1841	ribosomal large subunit assembly
KH172YL63_01400	COG0201	protein transport
KH172YL63_01410	COG0563	adenylate kinase activity
KH172YL63_01420	COG0024	Methionine aminopeptidase
KH172YL63_01430	COG2163	COG2163 Ribosomal protein L14E L6E L27E
KH172YL63_01440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KH172YL63_01450	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KH172YL63_01470	COG0202	RNA polymerase activity
KH172YL63_01480	COG0203	ribosomal protein L17
KH172YL63_01490	COG1122	ATPase activity
KH172YL63_01500	COG1122	ATPase activity
KH172YL63_01510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KH172YL63_01520	COG0101	tRNA pseudouridine synthase activity
KH172YL63_01530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KH172YL63_01540	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KH172YL63_01560	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_01570	COG0489	protein tyrosine kinase activity
KH172YL63_01590	COG2194	sulfuric ester hydrolase activity
KH172YL63_01600	COG0726	polysaccharide deacetylase
KH172YL63_01640	COG1595	DNA-templated transcription, initiation
KH172YL63_01650	COG5662	AntiSigma factor
KH172YL63_01660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KH172YL63_01670	COG4856	YbbR-like protein
KH172YL63_01680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KH172YL63_01700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KH172YL63_01720	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KH172YL63_01750	COG0523	cobalamin synthesis protein
KH172YL63_01760	COG0701	Predicted permease
KH172YL63_01790	COG3403	YqcI/YcgG family
KH172YL63_01810	COG2340	Cysteine-rich secretory protein family
KH172YL63_01820	COG2094	Belongs to the DNA glycosylase MPG family
KH172YL63_01840	COG0601	transmembrane transport
KH172YL63_01850	COG2861	carbohydrate metabolic process
KH172YL63_01860	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_01880	COG2814	Major facilitator Superfamily
KH172YL63_01920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KH172YL63_01930	COG1115	amino acid carrier protein
KH172YL63_01950	COG0517	IMP dehydrogenase activity
KH172YL63_01960	COG2340	Cysteine-rich secretory protein family
KH172YL63_01990	COG1597	lipid kinase activity
KH172YL63_02000	COG1238	metal cluster binding
KH172YL63_02030	COG0772	Belongs to the SEDS family
KH172YL63_02050	COG1489	DNA binding
KH172YL63_02070	COG4134	Bacterial extracellular solute-binding protein
KH172YL63_02110	COG0398	Pfam SNARE associated Golgi protein
KH172YL63_02130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KH172YL63_02170	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KH172YL63_02180	COG1181	Belongs to the D-alanine--D-alanine ligase family
KH172YL63_02190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KH172YL63_02210	COG0513	Belongs to the DEAD box helicase family
KH172YL63_02230	COG4294	response to UV
KH172YL63_02240	COG3402	PFAM membrane-flanked domain
KH172YL63_02250	COG3428	Bacterial PH domain
KH172YL63_02260	COG0705	Rhomboid family
KH172YL63_02270	COG0736	holo-[acyl-carrier-protein] synthase activity
KH172YL63_02280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KH172YL63_02300	COG0864	Transcriptional regulator
KH172YL63_02310	COG2337	Toxic component of a toxin-antitoxin (TA) module
KH172YL63_02320	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_02330	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_02340	COG2172	sigma factor antagonist activity
KH172YL63_02350	COG2208	phosphoserine phosphatase activity
KH172YL63_02360	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_02370	COG2172	sigma factor antagonist activity
KH172YL63_02380	COG1191	sigma factor activity
KH172YL63_02390	COG2208	phosphoserine phosphatase activity
KH172YL63_02400	COG2183	response to ionizing radiation
KH172YL63_02420	COG0802	atpase or kinase
KH172YL63_02430	COG1214	PFAM Peptidase M22, glycoprotease
KH172YL63_02440	COG0456	acetyltransferase
KH172YL63_02460	COG0488	(ABC) transporter
KH172YL63_02470	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KH172YL63_02480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KH172YL63_02490	COG0805	protein transport
KH172YL63_02510	COG1266	CAAX protease self-immunity
KH172YL63_02520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KH172YL63_02530	COG0459	protein refolding
KH172YL63_02540	COG0582	viral genome integration into host DNA
KH172YL63_02590	COG0582	viral genome integration into host DNA
KH172YL63_02650	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KH172YL63_02710	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KH172YL63_02790	COG3973	AAA domain
KH172YL63_02830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KH172YL63_02900	COG2304	oxidoreductase activity
KH172YL63_02970	COG2304	oxidoreductase activity
KH172YL63_03090	COG2304	oxidoreductase activity
KH172YL63_03130	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KH172YL63_03160	COG0714	Associated with various cellular activities
KH172YL63_03170	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KH172YL63_03180	COG1305	Transglutaminase-like
KH172YL63_03190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KH172YL63_03190	COG0519	Catalyzes the synthesis of GMP from XMP
KH172YL63_03200	COG2252	PERMEase
KH172YL63_03210	COG3711	transcriptional antiterminator
KH172YL63_03220	COG1263	PTS System
KH172YL63_03220	COG2190	(PTS) system
KH172YL63_03220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KH172YL63_03250	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KH172YL63_03270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KH172YL63_03280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KH172YL63_03290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KH172YL63_03310	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KH172YL63_03320	COG0047	phosphoribosylformylglycinamidine synthase activity
KH172YL63_03340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KH172YL63_03360	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KH172YL63_03380	COG0151	Belongs to the GarS family
KH172YL63_03410	COG1470	cell adhesion involved in biofilm formation
KH172YL63_03420	COG4496	protein, YerC YecD
KH172YL63_03430	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KH172YL63_03440	COG0210	DNA helicase
KH172YL63_03450	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KH172YL63_03460	COG4851	CamS sex pheromone cAM373 precursor
KH172YL63_03470	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KH172YL63_03480	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KH172YL63_03490	COG2224	Isocitrate lyase
KH172YL63_03500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KH172YL63_03510	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KH172YL63_03540	COG0505	Belongs to the CarA family
KH172YL63_03550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KH172YL63_03560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KH172YL63_03570	COG5506	Protein of unknown function (DUF1694)
KH172YL63_03600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KH172YL63_03690	COG2226	methyltransferase
KH172YL63_03720	COG1597	lipid kinase activity
KH172YL63_03780	COG0166	Belongs to the GPI family
KH172YL63_03790	COG4895	conserved protein (DUF2196)
KH172YL63_03800	COG1914	H( )-stimulated, divalent metal cation uptake system
KH172YL63_03810	COG1984	allophanate hydrolase subunit 2
KH172YL63_03820	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KH172YL63_03830	COG2814	Major facilitator Superfamily
KH172YL63_03850	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_03880	COG1126	abc transporter atp-binding protein
KH172YL63_03890	COG1595	DNA-templated transcription, initiation
KH172YL63_03910	COG1131	(ABC) transporter
KH172YL63_03920	COG1725	Transcriptional regulator
KH172YL63_03930	COG1131	(ABC) transporter
KH172YL63_03970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_03990	COG1595	DNA-templated transcription, initiation
KH172YL63_04020	COG3859	Proton-coupled thiamine transporter YuaJ
KH172YL63_04030	COG2966	Psort location CytoplasmicMembrane, score
KH172YL63_04040	COG3610	response to peptide
KH172YL63_04070	COG1132	(ABC) transporter
KH172YL63_04080	COG1132	(ABC) transporter
KH172YL63_04090	COG3871	stress protein (general stress protein 26)
KH172YL63_04110	COG2323	membrane
KH172YL63_04130	COG1115	amino acid carrier protein
KH172YL63_04150	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_04180	COG0584	glycerophosphoryl diester phosphodiesterase
KH172YL63_04190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KH172YL63_04210	COG2364	Membrane
KH172YL63_04220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KH172YL63_04220	COG1199	ATP-dependent helicase activity
KH172YL63_04230	COG2193	ferroxidase activity
KH172YL63_04260	COG1404	Belongs to the peptidase S8 family
KH172YL63_04270	COG2032	superoxide dismutase activity
KH172YL63_04280	COG0733	neurotransmitter:sodium symporter activity
KH172YL63_04290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KH172YL63_04300	COG0488	(ABC) transporter
KH172YL63_04320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_04330	COG1846	Transcriptional regulator
KH172YL63_04340	COG0477	Major facilitator Superfamily
KH172YL63_04350	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KH172YL63_04360	COG3396	Phenylacetate-CoA oxygenase
KH172YL63_04390	COG2151	metal-sulfur cluster biosynthetic enzyme
KH172YL63_04420	COG1024	Enoyl-CoA hydratase
KH172YL63_04430	COG1012	belongs to the aldehyde dehydrogenase family
KH172YL63_04440	COG1250	3-hydroxyacyl-CoA dehydrogenase
KH172YL63_04450	COG0183	Belongs to the thiolase family
KH172YL63_04470	COG3327	negative regulation of DNA-templated transcription, initiation
KH172YL63_04500	COG4120	Belongs to the binding-protein-dependent transport system permease family
KH172YL63_04560	COG0022	dehydrogenase e1 component
KH172YL63_04590	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KH172YL63_04600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KH172YL63_04610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KH172YL63_04620	COG0179	Fumarylacetoacetate (FAA) hydrolase
KH172YL63_04650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KH172YL63_04660	COG0129	dihydroxy-acid dehydratase activity
KH172YL63_04670	COG0028	Belongs to the TPP enzyme family
KH172YL63_04680	COG0440	acetolactate synthase activity
KH172YL63_04690	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KH172YL63_04700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KH172YL63_04720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KH172YL63_04730	COG0066	3-isopropylmalate dehydratase activity
KH172YL63_04740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KH172YL63_04760	COG0460	homoserine dehydrogenase
KH172YL63_04770	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KH172YL63_04780	COG0083	homoserine kinase activity
KH172YL63_04810	COG3852	Histidine kinase
KH172YL63_04840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KH172YL63_04860	COG0210	DNA helicase
KH172YL63_04890	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KH172YL63_04940	COG1737	Transcriptional regulator
KH172YL63_04950	COG2610	gluconate transmembrane transporter activity
KH172YL63_04960	COG1070	Carbohydrate kinase
KH172YL63_05030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KH172YL63_05050	COG0702	epimerase
KH172YL63_05070	COG1309	transcriptional regulator
KH172YL63_05080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KH172YL63_05090	COG2244	polysaccharide biosynthetic process
KH172YL63_05170	COG4585	Histidine kinase
KH172YL63_05180	COG2197	response regulator
KH172YL63_05220	COG0714	Associated with various cellular activities
KH172YL63_05310	COG1714	RDD family
KH172YL63_05340	COG1012	belongs to the aldehyde dehydrogenase family
KH172YL63_05350	COG2130	NADP-dependent
KH172YL63_05370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_05400	COG0288	reversible hydration of carbon dioxide
KH172YL63_05430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KH172YL63_05520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_05540	COG0488	(ABC) transporter
KH172YL63_05570	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KH172YL63_05630	COG1077	Cell shape determining protein MreB Mrl
KH172YL63_05640	COG0840	transmembrane signaling receptor activity
KH172YL63_05660	COG1607	acyl-coa hydrolase
KH172YL63_05670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KH172YL63_05740	COG2309	aminopeptidase activity
KH172YL63_05760	COG1959	2 iron, 2 sulfur cluster binding
KH172YL63_05820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KH172YL63_05830	COG1360	Flagellar Motor Protein
KH172YL63_05840	COG1115	amino acid carrier protein
KH172YL63_05850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KH172YL63_05860	COG2313	pseudouridylate synthase activity
KH172YL63_05870	COG5002	protein histidine kinase activity
KH172YL63_05880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KH172YL63_05890	COG0275	rRNA processing
KH172YL63_05900	COG3486	L-lysine 6-monooxygenase (NADPH) activity
KH172YL63_05910	COG0693	protein deglycase activity
KH172YL63_05920	COG4840	Belongs to the UPF0435 family
KH172YL63_05930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KH172YL63_05940	COG4980	gas vesicle protein
KH172YL63_05950	COG1295	ribonuclease BN
KH172YL63_05960	COG3275	phosphorelay sensor kinase activity
KH172YL63_05970	COG3279	Response regulator of the LytR AlgR family
KH172YL63_05980	COG1966	Carbon starvation protein
KH172YL63_06000	COG1595	DNA-templated transcription, initiation
KH172YL63_06050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KH172YL63_06090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KH172YL63_06100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KH172YL63_06110	COG2223	nitrite transmembrane transporter activity
KH172YL63_06130	COG3383	formate dehydrogenase (NAD+) activity
KH172YL63_06140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KH172YL63_06150	COG0303	'Molybdopterin
KH172YL63_06160	COG0314	molybdopterin synthase activity
KH172YL63_06170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KH172YL63_06180	COG0521	Mo-molybdopterin cofactor biosynthetic process
KH172YL63_06190	COG0725	ABC transporter, periplasmic molybdate-binding protein
KH172YL63_06200	COG4149	molybdate abc transporter
KH172YL63_06230	COG0746	molybdenum cofactor guanylyltransferase activity
KH172YL63_06250	COG0028	Belongs to the TPP enzyme family
KH172YL63_06270	COG2190	(PTS) system
KH172YL63_06270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KH172YL63_06270	COG1263	PTS System
KH172YL63_06280	COG2217	Heavy metal translocating P-type atpase
KH172YL63_06290	COG0477	Major facilitator Superfamily
KH172YL63_06310	COG0387	Pfam Sodium calcium exchanger
KH172YL63_06350	COG0535	radical SAM domain protein
KH172YL63_06420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KH172YL63_06430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KH172YL63_06440	COG3507	Belongs to the glycosyl hydrolase 43 family
KH172YL63_06450	COG1940	carbohydrate kinase activity
KH172YL63_06460	COG1653	transport
KH172YL63_06470	COG1175	transmembrane transport
KH172YL63_06480	COG0395	ABC-type sugar transport system, permease component
KH172YL63_06490	COG5578	integral membrane protein
KH172YL63_06510	COG1070	Carbohydrate kinase
KH172YL63_06520	COG0667	Aldo Keto reductase
KH172YL63_06530	COG2017	converts alpha-aldose to the beta-anomer
KH172YL63_06540	COG2814	Major facilitator Superfamily
KH172YL63_06540	COG0477	Major facilitator Superfamily
KH172YL63_06550	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KH172YL63_06580	COG1396	sequence-specific DNA binding
KH172YL63_06710	COG2211	Major facilitator Superfamily
KH172YL63_06720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KH172YL63_06730	COG1335	isochorismatase
KH172YL63_06820	COG1595	DNA-templated transcription, initiation
KH172YL63_06840	COG0772	Belongs to the SEDS family
KH172YL63_06900	COG0346	lactoylglutathione lyase activity
KH172YL63_06920	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_06980	COG1129	ABC transporter
KH172YL63_06980	COG0842	Transport permease protein
KH172YL63_07020	COG5278	phosphoserine phosphatase activity
KH172YL63_07020	COG0840	transmembrane signaling receptor activity
KH172YL63_07070	COG5646	InterPro IPR014922
KH172YL63_07090	COG3414	Phosphotransferase system galactitol-specific IIB component
KH172YL63_07100	COG3711	transcriptional antiterminator
KH172YL63_07100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KH172YL63_07110	COG0488	(ABC) transporter
KH172YL63_07140	COG0583	DNA-binding transcription factor activity
KH172YL63_07150	COG0730	response to heat
KH172YL63_07180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KH172YL63_07210	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_07240	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_07270	COG3711	transcriptional antiterminator
KH172YL63_07280	COG0246	Mannitol dehydrogenase
KH172YL63_07300	COG0019	diaminopimelate decarboxylase activity
KH172YL63_07350	COG0583	DNA-binding transcription factor activity
KH172YL63_07360	COG1511	domain protein
KH172YL63_07380	COG0501	Belongs to the peptidase M48B family
KH172YL63_07390	COG5632	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_07400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KH172YL63_07440	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KH172YL63_07460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KH172YL63_07470	COG0351	phosphomethylpyrimidine kinase
KH172YL63_07480	COG0352	thiamine-phosphate diphosphorylase activity
KH172YL63_07510	COG1136	(ABC) transporter
KH172YL63_07540	COG3459	Glycosyltransferase 36 associated
KH172YL63_07560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KH172YL63_07570	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_07590	COG3239	Fatty acid desaturase
KH172YL63_07600	COG2197	response regulator
KH172YL63_07610	COG1187	pseudouridine synthase activity
KH172YL63_07620	COG0789	Transcriptional regulator
KH172YL63_07650	COG1278	Cold shock
KH172YL63_07680	COG3290	protein histidine kinase activity
KH172YL63_07680	COG0840	transmembrane signaling receptor activity
KH172YL63_07690	COG1609	Transcriptional regulator
KH172YL63_07730	COG0395	ABC-type sugar transport system, permease component
KH172YL63_07750	COG0395	ABC-type sugar transport system, permease component
KH172YL63_07760	COG1175	transmembrane transport
KH172YL63_07790	COG3459	Glycosyltransferase 36 associated
KH172YL63_07810	COG1595	DNA-templated transcription, initiation
KH172YL63_07850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KH172YL63_07860	COG1115	amino acid carrier protein
KH172YL63_07880	COG2188	Transcriptional regulator
KH172YL63_07910	COG5001	Diguanylate cyclase
KH172YL63_07910	COG3300	MHYT domain
KH172YL63_07920	COG2824	Alkylphosphonate utilization operon protein PhnA
KH172YL63_07960	COG0640	Transcriptional regulator
KH172YL63_08020	COG1012	belongs to the aldehyde dehydrogenase family
KH172YL63_08080	COG1395	domain, Protein
KH172YL63_08100	COG1231	oxidoreductase activity
KH172YL63_08120	COG3708	Transcriptional regulator
KH172YL63_08120	COG2207	Transcriptional regulator
KH172YL63_08130	COG2132	Multicopper oxidase
KH172YL63_08170	COG2205	protein histidine kinase activity
KH172YL63_08180	COG0778	Nitroreductase
KH172YL63_08190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KH172YL63_08190	COG1918	ferrous iron import across plasma membrane
KH172YL63_08200	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KH172YL63_08210	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KH172YL63_08230	COG1737	Transcriptional regulator
KH172YL63_08270	COG0070	glutamate synthase
KH172YL63_08270	COG0069	glutamate synthase activity
KH172YL63_08270	COG0067	glutamate synthase
KH172YL63_08280	COG0493	'glutamate synthase
KH172YL63_08290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KH172YL63_08290	COG1263	PTS System
KH172YL63_08310	COG1657	PFAM Prenyltransferase squalene oxidase
KH172YL63_08340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KH172YL63_08370	COG1595	DNA-templated transcription, initiation
KH172YL63_08430	COG1607	acyl-coa hydrolase
KH172YL63_08480	COG2207	Transcriptional regulator
KH172YL63_08500	COG2268	Band 7 protein
KH172YL63_08510	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KH172YL63_08520	COG0737	Belongs to the 5'-nucleotidase family
KH172YL63_08530	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KH172YL63_08540	COG0277	FAD linked oxidase domain protein
KH172YL63_08550	COG0385	Bile acid
KH172YL63_08570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KH172YL63_08580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KH172YL63_08590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KH172YL63_08600	COG1120	ATPase activity
KH172YL63_08610	COG0492	ferredoxin-NADP+ reductase activity
KH172YL63_08630	COG0861	Integral membrane protein TerC family
KH172YL63_08660	COG0697	spore germination
KH172YL63_08700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KH172YL63_08710	COG2270	Major facilitator Superfamily
KH172YL63_08730	COG1664	Polymer-forming cytoskeletal
KH172YL63_08740	COG0789	Transcriptional regulator
KH172YL63_08750	COG2188	Transcriptional regulator
KH172YL63_08760	COG1131	(ABC) transporter
KH172YL63_08810	COG0542	response to heat
KH172YL63_08830	COG0561	phosphatase activity
KH172YL63_08840	COG1132	(ABC) transporter
KH172YL63_08860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KH172YL63_08900	COG1090	epimerase
KH172YL63_08940	COG0300	oxidoreductase activity
KH172YL63_08990	COG1988	membrane-bound metal-dependent
KH172YL63_09010	COG1194	a g-specific adenine glycosylase
KH172YL63_09030	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_09060	COG3557	Belongs to the UPF0374 family
KH172YL63_09070	COG1132	(ABC) transporter
KH172YL63_09080	COG0444	Belongs to the ABC transporter superfamily
KH172YL63_09090	COG4608	Belongs to the ABC transporter superfamily
KH172YL63_09100	COG0747	negative chemotaxis
KH172YL63_09130	COG4129	membrane
KH172YL63_09140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KH172YL63_09150	COG4555	ABC transporter
KH172YL63_09190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KH172YL63_09200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KH172YL63_09210	COG2096	Adenosyltransferase
KH172YL63_09220	COG0735	belongs to the Fur family
KH172YL63_09280	COG2972	Histidine kinase
KH172YL63_09290	COG2207	Transcriptional regulator
KH172YL63_09290	COG4753	response regulator
KH172YL63_09310	COG0673	inositol 2-dehydrogenase activity
KH172YL63_09320	COG0673	inositol 2-dehydrogenase activity
KH172YL63_09330	COG1082	Xylose isomerase domain protein TIM barrel
KH172YL63_09350	COG3382	B3 4 domain protein
KH172YL63_09360	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KH172YL63_09380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KH172YL63_09390	COG0778	Nitroreductase
KH172YL63_09400	COG2766	serine protein kinase
KH172YL63_09430	COG2718	Belongs to the UPF0229 family
KH172YL63_09450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KH172YL63_09470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KH172YL63_09480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KH172YL63_09510	COG0039	L-malate dehydrogenase activity
KH172YL63_09540	COG0406	alpha-ribazole phosphatase activity
KH172YL63_09550	COG2252	PERMEase
KH172YL63_09560	COG4187	Peptidase family M20/M25/M40
KH172YL63_09580	COG0778	Nitroreductase
KH172YL63_09590	COG1733	regulation of RNA biosynthetic process
KH172YL63_09610	COG1609	Transcriptional regulator
KH172YL63_09620	COG1970	mechanosensitive ion channel activity
KH172YL63_09640	COG2205	protein histidine kinase activity
KH172YL63_09660	COG3973	AAA domain
KH172YL63_09680	COG0656	L-ascorbic acid biosynthetic process
KH172YL63_09690	COG2259	Doxx family
KH172YL63_09700	COG1741	Belongs to the pirin family
KH172YL63_09710	COG0655	NAD(P)H dehydrogenase (quinone) activity
KH172YL63_09720	COG0564	pseudouridine synthase activity
KH172YL63_09750	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KH172YL63_09760	COG0366	Alpha amylase catalytic
KH172YL63_09770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KH172YL63_09770	COG3153	acetyltransferase
KH172YL63_09780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KH172YL63_09790	COG2203	Gaf domain
KH172YL63_09790	COG4585	Histidine kinase
KH172YL63_09800	COG2197	response regulator
KH172YL63_09810	COG0431	NADPH-dependent FMN reductase
KH172YL63_09840	COG2211	Major facilitator Superfamily
KH172YL63_09850	COG2719	SpoVR family
KH172YL63_09870	COG2364	Membrane
KH172YL63_09880	COG0471	metal ion transport
KH172YL63_09890	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_09900	COG2610	gluconate transmembrane transporter activity
KH172YL63_09910	COG1253	flavin adenine dinucleotide binding
KH172YL63_09970	COG4989	oxidoreductase activity
KH172YL63_10000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KH172YL63_10020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KH172YL63_10040	COG0084	hydrolase, TatD family'
KH172YL63_10060	COG1533	DNA photolyase activity
KH172YL63_10080	COG1301	dicarboxylic acid transport
KH172YL63_10090	COG0415	Belongs to the DNA photolyase family
KH172YL63_10120	COG2814	Major facilitator Superfamily
KH172YL63_10130	COG1595	DNA-templated transcription, initiation
KH172YL63_10160	COG0393	Putative heavy-metal-binding
KH172YL63_10170	COG1132	(ABC) transporter
KH172YL63_10180	COG1132	(ABC) transporter
KH172YL63_10230	COG0702	epimerase
KH172YL63_10240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KH172YL63_10250	COG0765	amino acid transport
KH172YL63_10260	COG1126	abc transporter atp-binding protein
KH172YL63_10270	COG1268	BioY protein
KH172YL63_10280	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_10290	COG0183	Belongs to the thiolase family
KH172YL63_10300	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_10310	COG0114	fumarate hydratase activity
KH172YL63_10340	COG3842	ATPase activity
KH172YL63_10350	COG2508	Transcriptional regulator
KH172YL63_10360	COG1937	Protein conserved in bacteria
KH172YL63_10410	COG0189	ligase activity
KH172YL63_10420	COG0189	ligase activity
KH172YL63_10450	COG4399	Belongs to the UPF0754 family
KH172YL63_10470	COG0561	phosphatase activity
KH172YL63_10480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KH172YL63_10500	COG1024	Enoyl-CoA hydratase
KH172YL63_10520	COG4152	abc transporter atp-binding protein
KH172YL63_10530	COG1668	transmembrane transport
KH172YL63_10540	COG0420	3'-5' exonuclease activity
KH172YL63_10550	COG4717	serine-type aminopeptidase activity
KH172YL63_10560	COG2814	Major facilitator Superfamily
KH172YL63_10570	COG3481	metal-dependent phosphohydrolase, HD sub domain
KH172YL63_10590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KH172YL63_10630	COG1846	Transcriptional regulator
KH172YL63_10670	COG0537	adenosine 5'-monophosphoramidase activity
KH172YL63_10680	COG1131	(ABC) transporter
KH172YL63_10690	COG4473	ABC transporter
KH172YL63_10720	COG1473	amidohydrolase
KH172YL63_10730	COG0671	phosphoesterase, PA-phosphatase related
KH172YL63_10740	COG3069	C4-dicarboxylate transmembrane transporter activity
KH172YL63_10760	COG4585	Histidine kinase
KH172YL63_10770	COG2197	response regulator
KH172YL63_10780	COG1335	isochorismatase
KH172YL63_10790	COG2329	Antibiotic biosynthesis monooxygenase
KH172YL63_10800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KH172YL63_10830	COG0456	acetyltransferase
KH172YL63_10850	COG1511	domain protein
KH172YL63_10870	COG1234	tRNA 3'-trailer cleavage
KH172YL63_10880	COG0095	Lipoate-protein ligase
KH172YL63_10890	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_10900	COG1024	Enoyl-CoA hydratase
KH172YL63_10940	COG2391	methyltransferase activity
KH172YL63_10950	COG5337	Spore coat protein CotH
KH172YL63_10960	COG1396	sequence-specific DNA binding
KH172YL63_10970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KH172YL63_10990	COG0501	Belongs to the peptidase M48B family
KH172YL63_11040	COG1506	peptidase
KH172YL63_11040	COG4946	Tricorn protease homolog
KH172YL63_11040	COG0823	Involved in the tonB-independent uptake of proteins
KH172YL63_11060	COG0398	Pfam SNARE associated Golgi protein
KH172YL63_11080	COG3437	response regulator, receiver
KH172YL63_11080	COG2770	Histidine kinase
KH172YL63_11090	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_11100	COG0183	Belongs to the thiolase family
KH172YL63_11110	COG2356	endonuclease I
KH172YL63_11150	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KH172YL63_11160	COG1074	ATP-dependent DNA helicase activity
KH172YL63_11170	COG1403	HNH endonuclease
KH172YL63_11240	COG2311	Membrane
KH172YL63_11250	COG0179	Fumarylacetoacetate (FAA) hydrolase
KH172YL63_11290	COG0367	asparagine synthase
KH172YL63_11330	COG0004	ammonium transporteR
KH172YL63_11340	COG0347	Belongs to the P(II) protein family
KH172YL63_11350	COG0534	Mate efflux family protein
KH172YL63_11370	COG2182	Extracellular solute-binding protein
KH172YL63_11380	COG1175	transmembrane transport
KH172YL63_11390	COG3833	ABC-type maltose transport systems, permease component
KH172YL63_11400	COG0366	Alpha amylase catalytic
KH172YL63_11400	COG1874	Beta-galactosidase
KH172YL63_11410	COG1609	Transcriptional regulator
KH172YL63_11420	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_11430	COG0446	pyridine nucleotide-disulphide oxidoreductase
KH172YL63_11440	COG1666	GTP binding
KH172YL63_11460	COG1307	EDD domain protein, DegV family
KH172YL63_11470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_11510	COG0561	phosphatase activity
KH172YL63_11520	COG1073	alpha beta
KH172YL63_11530	COG2151	metal-sulfur cluster biosynthetic enzyme
KH172YL63_11540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KH172YL63_11590	COG2267	carboxylic ester hydrolase activity
KH172YL63_11610	COG1744	ABC transporter substrate-binding protein PnrA-like
KH172YL63_11630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KH172YL63_11640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KH172YL63_11650	COG5504	Zn-dependent protease
KH172YL63_11670	COG0180	Tryptophanyl-tRNA synthetase
KH172YL63_11690	COG4166	transmembrane transport
KH172YL63_11700	COG0601	transmembrane transport
KH172YL63_11710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KH172YL63_11720	COG0444	Belongs to the ABC transporter superfamily
KH172YL63_11730	COG4608	Belongs to the ABC transporter superfamily
KH172YL63_11750	COG0456	acetyltransferase
KH172YL63_11760	COG1393	Belongs to the ArsC family
KH172YL63_11770	COG4862	establishment of competence for transformation
KH172YL63_11800	COG1164	Oligoendopeptidase f
KH172YL63_11830	COG2346	COG2346, Truncated hemoglobins
KH172YL63_11840	COG0741	lytic transglycosylase activity
KH172YL63_11850	COG4116	CYTH
KH172YL63_11870	COG2357	RelA SpoT domain protein
KH172YL63_11890	COG0564	pseudouridine synthase activity
KH172YL63_11900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KH172YL63_11910	COG2239	Acts as a magnesium transporter
KH172YL63_11920	COG0475	glutathione-regulated potassium exporter activity
KH172YL63_11920	COG0569	domain protein
KH172YL63_11940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KH172YL63_12010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KH172YL63_12030	COG2323	membrane
KH172YL63_12060	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KH172YL63_12070	COG2323	membrane
KH172YL63_12080	COG2153	protein acetylation
KH172YL63_12090	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KH172YL63_12100	COG2382	esterase
KH172YL63_12110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KH172YL63_12120	COG2358	TRAP transporter, solute receptor (TAXI family
KH172YL63_12160	COG3344	reverse transcriptase
KH172YL63_12210	COG1737	Transcriptional regulator
KH172YL63_12220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KH172YL63_12240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KH172YL63_12260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KH172YL63_12270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KH172YL63_12290	COG1764	response to oxidative stress
KH172YL63_12300	COG1278	Cold shock
KH172YL63_12330	COG1295	ribonuclease BN
KH172YL63_12340	COG3104	oligopeptide transport
KH172YL63_12360	COG1363	Peptidase, m42
KH172YL63_12370	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KH172YL63_12380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KH172YL63_12400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KH172YL63_12410	COG3300	MHYT domain
KH172YL63_12410	COG5001	Diguanylate cyclase
KH172YL63_12450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KH172YL63_12480	COG0861	Integral membrane protein TerC family
KH172YL63_12500	COG1191	sigma factor activity
KH172YL63_12530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KH172YL63_12590	COG3594	Acyltransferase
KH172YL63_12600	COG5002	protein histidine kinase activity
KH172YL63_12610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KH172YL63_12630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KH172YL63_12640	COG0436	Aminotransferase
KH172YL63_12660	COG1846	Transcriptional regulator
KH172YL63_12680	COG3949	Membrane
KH172YL63_12700	COG4873	Protein conserved in bacteria
KH172YL63_12720	COG3773	Cell wall hydrolase
KH172YL63_12740	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_12750	COG0714	Associated with various cellular activities
KH172YL63_12780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KH172YL63_12790	COG0390	transport system, permease component
KH172YL63_12810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KH172YL63_12820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KH172YL63_12830	COG0456	acetyltransferase
KH172YL63_12850	COG0436	Aminotransferase
KH172YL63_12860	COG0598	Magnesium transport protein CorA
KH172YL63_12880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KH172YL63_12890	COG0720	synthase
KH172YL63_12900	COG0602	queuosine metabolic process
KH172YL63_12920	COG0784	Response regulator, receiver
KH172YL63_12920	COG0835	chemotaxis
KH172YL63_12940	COG3300	MHYT domain
KH172YL63_12940	COG5001	Diguanylate cyclase
KH172YL63_12960	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_12970	COG2200	EAL domain
KH172YL63_13010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_13020	COG4703	Protein of unknown function (DUF1797)
KH172YL63_13030	COG0517	IMP dehydrogenase activity
KH172YL63_13040	COG0477	Major facilitator Superfamily
KH172YL63_13060	COG0583	DNA-binding transcription factor activity
KH172YL63_13080	COG1473	amidohydrolase
KH172YL63_13090	COG0668	transmembrane transport
KH172YL63_13100	COG1132	(ABC) transporter
KH172YL63_13110	COG1132	(ABC) transporter
KH172YL63_13120	COG1271	oxidase subunit
KH172YL63_13130	COG1294	oxidase, subunit
KH172YL63_13140	COG0569	domain protein
KH172YL63_13150	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KH172YL63_13170	COG0561	phosphatase activity
KH172YL63_13220	COG0022	dehydrogenase e1 component
KH172YL63_13270	COG0726	polysaccharide deacetylase
KH172YL63_13290	COG1982	Orn Lys Arg decarboxylase major
KH172YL63_13310	COG4476	Belongs to the UPF0223 family
KH172YL63_13340	COG0483	inositol monophosphate 1-phosphatase activity
KH172YL63_13390	COG4896	Protein conserved in bacteria
KH172YL63_13440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KH172YL63_13450	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KH172YL63_13460	COG2066	Belongs to the glutaminase family
KH172YL63_13470	COG4838	Belongs to the UPF0358 family
KH172YL63_13480	COG0772	Belongs to the SEDS family
KH172YL63_13490	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KH172YL63_13540	COG1845	cytochrome c oxidase, subunit III
KH172YL63_13560	COG3336	cytochrome c oxidase
KH172YL63_13600	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KH172YL63_13610	COG2340	Cysteine-rich secretory protein family
KH172YL63_13660	COG3679	Belongs to the UPF0342 family
KH172YL63_13710	COG0742	ribosomal rna small subunit methyltransferase
KH172YL63_13720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KH172YL63_13730	COG3314	Sporulation integral membrane protein YlbJ
KH172YL63_13740	COG1752	Esterase of the alpha-beta hydrolase superfamily
KH172YL63_13750	COG3480	Lon protease (S16) C-terminal proteolytic domain
KH172YL63_13760	COG1323	Belongs to the UPF0348 family
KH172YL63_13770	COG1399	metal-binding, possibly nucleic acid-binding protein
KH172YL63_13780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KH172YL63_13790	COG1024	Enoyl-CoA hydratase
KH172YL63_13810	COG0454	-acetyltransferase
KH172YL63_13820	COG0439	Biotin carboxylase
KH172YL63_13830	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KH172YL63_13840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KH172YL63_13850	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KH172YL63_13870	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KH172YL63_13880	COG2001	Belongs to the MraZ family
KH172YL63_13920	COG0768	penicillin binding
KH172YL63_13950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KH172YL63_13960	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KH172YL63_13970	COG0772	Belongs to the SEDS family
KH172YL63_13980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KH172YL63_13990	COG3879	Bacterial protein of unknown function (DUF881)
KH172YL63_14000	COG3879	Bacterial protein of unknown function (DUF881)
KH172YL63_14010	COG3856	small basic protein
KH172YL63_14020	COG0849	cell division
KH172YL63_14030	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KH172YL63_14050	COG1191	sigma factor activity
KH172YL63_14060	COG1191	sigma factor activity
KH172YL63_14070	COG1873	PFAM PRC-barrel domain
KH172YL63_14090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KH172YL63_14100	COG1799	cell septum assembly
KH172YL63_14110	COG0762	integral membrane protein
KH172YL63_14120	COG2302	S4 RNA-binding domain
KH172YL63_14130	COG3599	regulation of cell shape
KH172YL63_14160	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KH172YL63_14170	COG0564	pseudouridine synthase activity
KH172YL63_14180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KH172YL63_14190	COG2233	PERMEase
KH172YL63_14210	COG0540	Belongs to the ATCase OTCase family
KH172YL63_14220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KH172YL63_14240	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KH172YL63_14250	COG0543	2 iron, 2 sulfur cluster binding
KH172YL63_14260	COG0167	dihydroorotate dehydrogenase activity
KH172YL63_14300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KH172YL63_14310	COG1561	YicC-like family, N-terminal region
KH172YL63_14330	COG0194	GDP metabolic process
KH172YL63_14350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KH172YL63_14360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KH172YL63_14370	COG0242	peptide deformylase activity
KH172YL63_14380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KH172YL63_14390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KH172YL63_14390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KH172YL63_14400	COG0631	protein serine/threonine phosphatase activity
KH172YL63_14410	COG2815	serine threonine protein kinase
KH172YL63_14410	COG0515	serine threonine protein kinase
KH172YL63_14430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KH172YL63_14440	COG1564	THIamine pyrophosphokinase
KH172YL63_14450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KH172YL63_14460	COG1302	Protein conserved in bacteria
KH172YL63_14470	COG1461	Dihydroxyacetone kinase
KH172YL63_14480	COG1760	l-serine dehydratase
KH172YL63_14490	COG1760	l-serine dehydratase
KH172YL63_14500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KH172YL63_14510	COG1349	DNA-binding transcription factor activity
KH172YL63_14520	COG0416	fatty acid biosynthetic process
KH172YL63_14530	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KH172YL63_14540	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_14550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KH172YL63_14570	COG1196	nuclear chromosome segregation
KH172YL63_14580	COG0552	protein localization to endoplasmic reticulum
KH172YL63_14590	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KH172YL63_14600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KH172YL63_14610	COG0228	four-way junction DNA binding
KH172YL63_14620	COG1837	Belongs to the UPF0109 family
KH172YL63_14640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KH172YL63_14650	COG0336	Belongs to the RNA methyltransferase TrmD family
KH172YL63_14660	COG0335	large ribosomal subunit rRNA binding
KH172YL63_14690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KH172YL63_14710	COG2257	FlhB HrpN YscU SpaS Family
KH172YL63_14730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KH172YL63_14740	COG0758	DNA mediated transformation
KH172YL63_14750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KH172YL63_14760	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KH172YL63_14770	COG4974	Belongs to the 'phage' integrase family
KH172YL63_14780	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KH172YL63_14790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KH172YL63_14800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KH172YL63_14810	COG1815	bacterial-type flagellum-dependent cell motility
KH172YL63_14820	COG1558	bacterial-type flagellum-dependent cell motility
KH172YL63_14830	COG1677	Flagellar hook-basal body complex protein FliE
KH172YL63_14840	COG1766	The M ring may be actively involved in energy transduction
KH172YL63_14850	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KH172YL63_14870	COG1157	protein secretion by the type III secretion system
KH172YL63_14880	COG2882	bacterial-type flagellum organization
KH172YL63_14900	COG3144	bacterial-type flagellum assembly
KH172YL63_14910	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KH172YL63_14940	COG1582	Flagellar protein (FlbD)
KH172YL63_14950	COG1580	Controls the rotational direction of flagella during chemotaxis
KH172YL63_14960	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KH172YL63_14970	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KH172YL63_14970	COG1776	CheC inhibitor of MCP methylation
KH172YL63_14980	COG2201	protein-glutamate methylesterase activity
KH172YL63_14990	COG3190	flagellar
KH172YL63_15000	COG1338	Plays a role in the flagellum-specific transport system
KH172YL63_15010	COG1987	bacterial-type flagellum assembly
KH172YL63_15020	COG1684	flagellar biosynthetic protein fliR
KH172YL63_15030	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KH172YL63_15040	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KH172YL63_15050	COG1419	protein localization to endoplasmic reticulum
KH172YL63_15060	COG1419	protein localization to endoplasmic reticulum
KH172YL63_15070	COG0455	bacterial-type flagellum organization
KH172YL63_15080	COG2201	protein-glutamate methylesterase activity
KH172YL63_15090	COG0643	Histidine kinase
KH172YL63_15090	COG2198	Histidine kinase
KH172YL63_15100	COG0835	chemotaxis
KH172YL63_15110	COG1776	CheC inhibitor of MCP methylation
KH172YL63_15120	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KH172YL63_15130	COG1191	sigma factor activity
KH172YL63_15160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KH172YL63_15190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KH172YL63_15200	COG4589	Belongs to the CDS family
KH172YL63_15220	COG0750	zinc metalloprotease
KH172YL63_15240	COG2176	DNA-directed DNA polymerase activity
KH172YL63_15250	COG0779	Required for maturation of 30S ribosomal subunits
KH172YL63_15260	COG0195	Participates in both transcription termination and antitermination
KH172YL63_15270	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KH172YL63_15280	COG1358	cellular component organization or biogenesis
KH172YL63_15290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KH172YL63_15300	COG1550	Protein conserved in bacteria
KH172YL63_15310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KH172YL63_15320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KH172YL63_15330	COG0196	riboflavin kinase activity
KH172YL63_15340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KH172YL63_15350	COG1185	polyribonucleotide nucleotidyltransferase activity
KH172YL63_15360	COG0726	polysaccharide deacetylase
KH172YL63_15370	COG0612	Peptidase, M16
KH172YL63_15380	COG1873	PFAM PRC-barrel domain
KH172YL63_15390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KH172YL63_15400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KH172YL63_15410	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KH172YL63_15420	COG0527	aspartate kinase activity
KH172YL63_15440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KH172YL63_15450	COG0740	serine-type endopeptidase activity
KH172YL63_15470	COG4980	gas vesicle protein
KH172YL63_15470	COG1674	ftsk spoiiie
KH172YL63_15480	COG2188	Transcriptional regulator
KH172YL63_15530	COG0612	Peptidase, M16
KH172YL63_15540	COG0612	Peptidase, M16
KH172YL63_15550	COG0300	oxidoreductase activity
KH172YL63_15580	COG1426	Protein conserved in bacteria
KH172YL63_15590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KH172YL63_15600	COG1546	Belongs to the CinA family
KH172YL63_15600	COG1058	Belongs to the CinA family
KH172YL63_15610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KH172YL63_15630	COG1692	metallophosphoesterase
KH172YL63_15640	COG2359	stage V sporulation protein S
KH172YL63_15660	COG0674	pyruvate-flavodoxin oxidoreductase activity
KH172YL63_15660	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KH172YL63_15670	COG1013	pyruvate-flavodoxin oxidoreductase activity
KH172YL63_15730	COG1216	Glycosyl transferase, family 2
KH172YL63_15780	COG0438	transferase activity, transferring glycosyl groups
KH172YL63_15800	COG1086	Polysaccharide biosynthesis protein
KH172YL63_15850	COG0529	Catalyzes the synthesis of activated sulfate
KH172YL63_15860	COG3273	potassium ion transport
KH172YL63_15860	COG0471	metal ion transport
KH172YL63_15870	COG2046	Belongs to the sulfate adenylyltransferase family
KH172YL63_15900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KH172YL63_15910	COG4550	Control of competence regulator ComK, YlbF/YmcA
KH172YL63_15930	COG0551	DNA topoisomerase type I activity
KH172YL63_15930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KH172YL63_15950	COG1966	Carbon starvation protein
KH172YL63_16040	COG1012	belongs to the aldehyde dehydrogenase family
KH172YL63_16050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KH172YL63_16060	COG2720	vancomycin resistance protein
KH172YL63_16090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KH172YL63_16100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KH172YL63_16110	COG0277	FAD linked oxidase domain protein
KH172YL63_16120	COG2271	Major facilitator Superfamily
KH172YL63_16160	COG0464	growth
KH172YL63_16170	COG2860	membrane
KH172YL63_16180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KH172YL63_16190	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KH172YL63_16200	COG0789	Transcriptional regulator
KH172YL63_16210	COG0174	glutamine synthetase
KH172YL63_16220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KH172YL63_16230	COG1388	LysM domain
KH172YL63_16240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KH172YL63_16250	COG4224	UPF0291 protein
KH172YL63_16280	COG3763	UPF0154 protein
KH172YL63_16480	COG0457	Tetratricopeptide repeat
KH172YL63_16480	COG0515	serine threonine protein kinase
KH172YL63_16610	COG0785	Cytochrome C biogenesis protein
KH172YL63_16620	COG2201	protein-glutamate methylesterase activity
KH172YL63_16630	COG4846	Membrane protein involved in cytochrome C biogenesis
KH172YL63_16640	COG1994	Peptidase M50
KH172YL63_16660	COG3852	Histidine kinase
KH172YL63_16720	COG0419	ATPase involved in DNA repair
KH172YL63_16770	COG5146	pantothenate kinase activity
KH172YL63_16780	COG1999	signal sequence binding
KH172YL63_16790	COG1247	-acetyltransferase
KH172YL63_16870	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KH172YL63_16900	COG1063	alcohol dehydrogenase
KH172YL63_16910	COG0626	cystathionine gamma-synthase activity
KH172YL63_16920	COG0626	cystathionine gamma-synthase activity
KH172YL63_16930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KH172YL63_16930	COG0646	methionine synthase
KH172YL63_16940	COG1410	methionine synthase
KH172YL63_16940	COG0646	methionine synthase
KH172YL63_16980	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_16990	COG0346	lactoylglutathione lyase activity
KH172YL63_17000	COG0400	carboxylic ester hydrolase activity
KH172YL63_17030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KH172YL63_17030	COG2169	Transcriptional regulator
KH172YL63_17050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_17070	COG0584	glycerophosphoryl diester phosphodiesterase
KH172YL63_17100	COG2267	carboxylic ester hydrolase activity
KH172YL63_17110	COG5522	Integral membrane protein (intg_mem_TP0381)
KH172YL63_17120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KH172YL63_17170	COG2205	protein histidine kinase activity
KH172YL63_17180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_17190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KH172YL63_17240	COG1183	phosphatidylcholine synthase activity
KH172YL63_17280	COG1695	Transcriptional regulator
KH172YL63_17290	COG0167	dihydroorotate dehydrogenase activity
KH172YL63_17310	COG0659	secondary active sulfate transmembrane transporter activity
KH172YL63_17360	COG2226	methyltransferase
KH172YL63_17380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_17400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KH172YL63_17410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KH172YL63_17430	COG2814	Major facilitator Superfamily
KH172YL63_17480	COG2318	DinB family
KH172YL63_17510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KH172YL63_17520	COG1695	Transcriptional regulator
KH172YL63_17540	COG3386	PFAM SMP-30 Gluconolaconase
KH172YL63_17560	COG4122	O-methyltransferase activity
KH172YL63_17570	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KH172YL63_17600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KH172YL63_17610	COG2239	Acts as a magnesium transporter
KH172YL63_17620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KH172YL63_17660	COG1131	(ABC) transporter
KH172YL63_17690	COG0477	Major facilitator Superfamily
KH172YL63_17700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KH172YL63_17710	COG1309	transcriptional regulator
KH172YL63_17730	COG0517	IMP dehydrogenase activity
KH172YL63_17730	COG1125	glycine betaine transport
KH172YL63_17740	COG1174	glycine betaine transport
KH172YL63_17760	COG1216	Glycosyl transferase, family 2
KH172YL63_17810	COG3655	Transcriptional regulator
KH172YL63_17830	COG0596	Alpha beta hydrolase
KH172YL63_17840	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_17920	COG3264	Mechanosensitive ion channel
KH172YL63_17920	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KH172YL63_17930	COG1597	lipid kinase activity
KH172YL63_17940	COG0322	excinuclease ABC activity
KH172YL63_17960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KH172YL63_18000	COG0583	DNA-binding transcription factor activity
KH172YL63_18010	COG0372	Belongs to the citrate synthase family
KH172YL63_18020	COG0346	lactoylglutathione lyase activity
KH172YL63_18080	COG1131	(ABC) transporter
KH172YL63_18090	COG0842	Transport permease protein
KH172YL63_18110	COG2304	oxidoreductase activity
KH172YL63_18190	COG0456	acetyltransferase
KH172YL63_18300	COG3344	reverse transcriptase
KH172YL63_18310	COG3344	reverse transcriptase
KH172YL63_18320	COG2362	D-Aminopeptidase
KH172YL63_18330	COG0601	transmembrane transport
KH172YL63_18340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KH172YL63_18350	COG0444	Belongs to the ABC transporter superfamily
KH172YL63_18360	COG4166	transmembrane transport
KH172YL63_18370	COG1619	proteins homologs of microcin C7 resistance protein MccF
KH172YL63_18380	COG4948	Mandelate Racemase Muconate Lactonizing
KH172YL63_18390	COG0791	NLP P60 protein
KH172YL63_18400	COG4608	Belongs to the ABC transporter superfamily
KH172YL63_18480	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_18520	COG0456	acetyltransferase
KH172YL63_18560	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KH172YL63_18570	COG2340	Cysteine-rich secretory protein family
KH172YL63_18630	COG4326	sporulation control protein
KH172YL63_18650	COG4264	IucA IucC family
KH172YL63_18680	COG0019	diaminopimelate decarboxylase activity
KH172YL63_18700	COG0789	Transcriptional regulator
KH172YL63_18710	COG1253	flavin adenine dinucleotide binding
KH172YL63_18750	COG1619	proteins homologs of microcin C7 resistance protein MccF
KH172YL63_18770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KH172YL63_18790	COG1214	PFAM Peptidase M22, glycoprotease
KH172YL63_18790	COG0456	acetyltransferase
KH172YL63_18810	COG2309	aminopeptidase activity
KH172YL63_18830	COG1349	DNA-binding transcription factor activity
KH172YL63_18840	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KH172YL63_18850	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KH172YL63_18870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KH172YL63_18910	COG0006	proline dipeptidase activity
KH172YL63_18930	COG4191	Histidine kinase
KH172YL63_18950	COG1380	Effector of murein hydrolase LrgA
KH172YL63_18960	COG1346	cytolysis
KH172YL63_18980	COG0024	Methionine aminopeptidase
KH172YL63_18990	COG0840	transmembrane signaling receptor activity
KH172YL63_19010	COG3584	3D domain protein
KH172YL63_19010	COG1388	LysM domain
KH172YL63_19020	COG3584	3D domain protein
KH172YL63_19020	COG1388	LysM domain
KH172YL63_19030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KH172YL63_19060	COG0840	transmembrane signaling receptor activity
KH172YL63_19120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KH172YL63_19130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_19170	COG0824	Thioesterase
KH172YL63_19190	COG4841	protein insertion into membrane
KH172YL63_19210	COG2843	Capsule synthesis protein
KH172YL63_19220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KH172YL63_19230	COG2233	PERMEase
KH172YL63_19240	COG0517	IMP dehydrogenase activity
KH172YL63_19240	COG1125	glycine betaine transport
KH172YL63_19250	COG1174	glycine betaine transport
KH172YL63_19260	COG1732	Glycine betaine
KH172YL63_19270	COG1832	CoA-binding protein
KH172YL63_19280	COG0187	DNA topoisomerase II activity
KH172YL63_19290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KH172YL63_19300	COG1115	amino acid carrier protein
KH172YL63_19380	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
KH172YL63_19390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KH172YL63_19410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KH172YL63_19420	COG0529	Catalyzes the synthesis of activated sulfate
KH172YL63_19440	COG0306	phosphate transporter
KH172YL63_19460	COG5583	Uncharacterized small protein (DUF2292)
KH172YL63_19490	COG2030	dehydratase
KH172YL63_19500	COG0352	thiamine-phosphate diphosphorylase activity
KH172YL63_19510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KH172YL63_19520	COG2022	thiamine diphosphate biosynthetic process
KH172YL63_19530	COG2104	thiamine diphosphate biosynthetic process
KH172YL63_19540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KH172YL63_19550	COG0352	thiamine-phosphate diphosphorylase activity
KH172YL63_19570	COG1122	ATPase activity
KH172YL63_19580	COG4721	ABC-type cobalt transport system, permease component
KH172YL63_19590	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KH172YL63_19600	COG2197	response regulator
KH172YL63_19610	COG4585	Histidine kinase
KH172YL63_19690	COG0708	Exodeoxyribonuclease III
KH172YL63_19720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_19740	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KH172YL63_19760	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KH172YL63_19770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KH172YL63_19790	COG1011	Hydrolase
KH172YL63_19830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KH172YL63_19870	COG0693	protein deglycase activity
KH172YL63_19880	COG2084	Dehydrogenase
KH172YL63_19910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_19910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_19920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_19920	COG0425	Belongs to the sulfur carrier protein TusA family
KH172YL63_19940	COG0745	RESPONSE REGULATOR receiver
KH172YL63_19950	COG5002	protein histidine kinase activity
KH172YL63_19960	COG4086	secreted protein
KH172YL63_19970	COG4191	Histidine kinase
KH172YL63_19980	COG0730	response to heat
KH172YL63_19990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_19990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_20000	COG0425	Belongs to the sulfur carrier protein TusA family
KH172YL63_20000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_20010	COG2210	Belongs to the sulfur carrier protein TusA family
KH172YL63_20020	COG0425	Belongs to the sulfur carrier protein TusA family
KH172YL63_20030	COG1937	Protein conserved in bacteria
KH172YL63_20050	COG0003	Pfam Anion-transporting ATPase
KH172YL63_20070	COG1966	Carbon starvation protein
KH172YL63_20140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KH172YL63_20160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KH172YL63_20160	COG0517	IMP dehydrogenase activity
KH172YL63_20170	COG2176	DNA-directed DNA polymerase activity
KH172YL63_20180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KH172YL63_20190	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KH172YL63_20240	COG2096	Adenosyltransferase
KH172YL63_20270	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KH172YL63_20290	COG1120	ATPase activity
KH172YL63_20300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KH172YL63_20310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KH172YL63_20320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KH172YL63_20350	COG0463	Glycosyl transferase, family 2
KH172YL63_20370	COG2996	Protein conserved in bacteria
KH172YL63_20380	COG2252	PERMEase
KH172YL63_20390	COG2223	nitrite transmembrane transporter activity
KH172YL63_20400	COG3973	AAA domain
KH172YL63_20440	COG4807	Protein conserved in bacteria
KH172YL63_20510	COG1181	Belongs to the D-alanine--D-alanine ligase family
KH172YL63_20520	COG0840	transmembrane signaling receptor activity
KH172YL63_20530	COG3852	Histidine kinase
KH172YL63_20600	COG0662	Cupin 2, conserved barrel domain protein
KH172YL63_20610	COG2323	membrane
KH172YL63_20620	COG1132	(ABC) transporter
KH172YL63_20630	COG1132	(ABC) transporter
KH172YL63_20660	COG0300	oxidoreductase activity
KH172YL63_20680	COG0385	Bile acid
KH172YL63_20700	COG1454	alcohol dehydrogenase
KH172YL63_20710	COG2188	Transcriptional regulator
KH172YL63_20720	COG3773	Cell wall hydrolase
KH172YL63_20790	COG1393	Belongs to the ArsC family
KH172YL63_20820	COG0384	phenazine biosynthesis protein PhzF
KH172YL63_20910	COG1595	DNA-templated transcription, initiation
KH172YL63_20940	COG0584	glycerophosphoryl diester phosphodiesterase
KH172YL63_20970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KH172YL63_20980	COG3739	integral membrane protein
KH172YL63_21140	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
KH172YL63_21190	COG1595	DNA-templated transcription, initiation
KH172YL63_21210	COG5002	protein histidine kinase activity
KH172YL63_21240	COG3706	GGDEF domain
KH172YL63_21290	COG2832	Protein of unknown function (DUF454)
KH172YL63_21460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KH172YL63_21470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KH172YL63_21480	COG0640	Transcriptional regulator
KH172YL63_21680	COG1131	(ABC) transporter
KH172YL63_21700	COG1595	DNA-templated transcription, initiation
KH172YL63_21760	COG0546	phosphoglycolate phosphatase activity
KH172YL63_21820	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_21900	COG0346	lactoylglutathione lyase activity
KH172YL63_22070	COG0305	Participates in initiation and elongation during chromosome replication
KH172YL63_22130	COG0494	nUDIX hydrolase
KH172YL63_22140	COG1061	Type III restriction enzyme res subunit
KH172YL63_22170	COG1396	sequence-specific DNA binding
KH172YL63_22230	COG0473	3-isopropylmalate dehydrogenase activity
KH172YL63_22240	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_22270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KH172YL63_22280	COG0183	Belongs to the thiolase family
KH172YL63_22290	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_22300	COG1024	Enoyl-CoA hydratase
KH172YL63_22310	COG1250	3-hydroxyacyl-CoA dehydrogenase
KH172YL63_22330	COG2358	TRAP transporter, solute receptor (TAXI family
KH172YL63_22350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KH172YL63_22370	COG3829	transcription factor binding
KH172YL63_22370	COG3290	protein histidine kinase activity
KH172YL63_22480	COG3853	Toxic anion resistance protein (TelA)
KH172YL63_22510	COG1358	cellular component organization or biogenesis
KH172YL63_22540	COG0861	Integral membrane protein TerC family
KH172YL63_22550	COG2310	stress, protein
KH172YL63_22560	COG2310	stress, protein
KH172YL63_22570	COG2310	stress, protein
KH172YL63_22610	COG2318	DinB family
KH172YL63_22620	COG0412	Dienelactone hydrolase
KH172YL63_22690	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KH172YL63_22730	COG2205	protein histidine kinase activity
KH172YL63_22740	COG0697	spore germination
KH172YL63_22780	COG1309	transcriptional regulator
KH172YL63_22790	COG2814	Major facilitator Superfamily
KH172YL63_22840	COG1131	(ABC) transporter
KH172YL63_22930	COG0446	pyridine nucleotide-disulphide oxidoreductase
KH172YL63_22990	COG2814	Major facilitator Superfamily
KH172YL63_23000	COG0450	alkyl hydroperoxide reductase
KH172YL63_23010	COG3634	alkyl hydroperoxide reductase activity
KH172YL63_23080	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_23090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KH172YL63_23100	COG0183	Belongs to the thiolase family
KH172YL63_23110	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_23120	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_23130	COG3829	transcription factor binding
KH172YL63_23130	COG3290	protein histidine kinase activity
KH172YL63_23190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_23200	COG0537	adenosine 5'-monophosphoramidase activity
KH172YL63_23240	COG0456	acetyltransferase
KH172YL63_23320	COG0604	alcohol dehydrogenase
KH172YL63_23360	COG1131	(ABC) transporter
KH172YL63_23470	COG1164	Oligoendopeptidase f
KH172YL63_23510	COG0702	epimerase
KH172YL63_23600	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_23620	COG1595	DNA-templated transcription, initiation
KH172YL63_23630	COG0500	methyltransferase
KH172YL63_23720	COG1309	transcriptional regulator
KH172YL63_23750	COG0579	oxidoreductase
KH172YL63_23770	COG2186	Transcriptional regulator
KH172YL63_23800	COG1131	(ABC) transporter
KH172YL63_23850	COG4213	ABC transporter substrate-binding protein
KH172YL63_23860	COG4753	response regulator
KH172YL63_23860	COG2207	Transcriptional regulator
KH172YL63_23870	COG2972	Histidine kinase
KH172YL63_23890	COG1172	Belongs to the binding-protein-dependent transport system permease family
KH172YL63_23900	COG1129	ABC transporter
KH172YL63_23910	COG4213	ABC transporter substrate-binding protein
KH172YL63_23950	COG1193	negative regulation of DNA recombination
KH172YL63_23970	COG3339	Conserved Protein
KH172YL63_23980	COG0488	(ABC) transporter
KH172YL63_23990	COG0514	ATP-dependent DNA helicase (RecQ)
KH172YL63_24090	COG1686	Belongs to the peptidase S11 family
KH172YL63_24100	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
KH172YL63_24110	COG3853	Toxic anion resistance protein (TelA)
KH172YL63_24130	COG4548	von Willebrand factor, type A
KH172YL63_24140	COG0714	Associated with various cellular activities
KH172YL63_24150	COG0454	-acetyltransferase
KH172YL63_24150	COG0456	acetyltransferase
KH172YL63_24170	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KH172YL63_24200	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KH172YL63_24200	COG2105	PFAM AIG2 family protein
KH172YL63_24210	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_24240	COG0508	dehydrogenase complex catalyzes the overall conversion of
KH172YL63_24250	COG0567	Dehydrogenase, E1 component
KH172YL63_24270	COG5002	protein histidine kinase activity
KH172YL63_24280	COG0745	RESPONSE REGULATOR receiver
KH172YL63_24290	COG2814	Major facilitator Superfamily
KH172YL63_24320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KH172YL63_24350	COG0432	Pfam Uncharacterised protein family UPF0047
KH172YL63_24360	COG3011	Protein conserved in bacteria
KH172YL63_24370	COG0406	alpha-ribazole phosphatase activity
KH172YL63_24380	COG1366	Belongs to the anti-sigma-factor antagonist family
KH172YL63_24500	COG2076	Multidrug Resistance protein
KH172YL63_24530	COG0697	spore germination
KH172YL63_24540	COG3541	Predicted nucleotidyltransferase
KH172YL63_24550	COG0628	permease
KH172YL63_24580	COG3340	Belongs to the peptidase S51 family
KH172YL63_24590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KH172YL63_24600	COG2356	endonuclease I
KH172YL63_24630	COG1278	Cold shock
KH172YL63_24650	COG1970	mechanosensitive ion channel activity
KH172YL63_24750	COG2226	methyltransferase
KH172YL63_24760	COG1619	proteins homologs of microcin C7 resistance protein MccF
KH172YL63_24820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KH172YL63_24830	COG0512	Glutamine amidotransferase of anthranilate synthase
KH172YL63_24830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KH172YL63_24860	COG4145	pantothenate transmembrane transporter activity
KH172YL63_24890	COG0671	phosphoesterase, PA-phosphatase related
KH172YL63_24900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KH172YL63_24910	COG1793	dna ligase
KH172YL63_24910	COG3285	dna ligase
KH172YL63_24940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KH172YL63_24970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KH172YL63_24970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KH172YL63_24980	COG0307	riboflavin synthase, alpha
KH172YL63_24990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KH172YL63_24990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KH172YL63_25020	COG4667	esterase of the alpha-beta hydrolase superfamily
KH172YL63_25050	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KH172YL63_25060	COG1131	(ABC) transporter
KH172YL63_25100	COG0586	Pfam SNARE associated Golgi protein
KH172YL63_25110	COG1228	amidohydrolase
KH172YL63_25150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KH172YL63_25170	COG1215	transferase activity, transferring glycosyl groups
KH172YL63_25200	COG0534	Mate efflux family protein
KH172YL63_25210	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_25220	COG2340	Cysteine-rich secretory protein family
KH172YL63_25260	COG0477	Major facilitator Superfamily
KH172YL63_25270	COG1846	Transcriptional regulator
KH172YL63_25300	COG0523	cobalamin synthesis protein
KH172YL63_25320	COG3409	Peptidoglycan-binding domain 1 protein
KH172YL63_25320	COG0793	Belongs to the peptidase S41A family
KH172YL63_25330	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_25370	COG0697	spore germination
KH172YL63_25380	COG1876	peptidase activity
KH172YL63_25430	COG4326	sporulation control protein
KH172YL63_25440	COG0515	serine threonine protein kinase
KH172YL63_25490	COG4479	Belongs to the UPF0346 family
KH172YL63_25510	COG1509	lysine 2,3-aminomutase activity
KH172YL63_25530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KH172YL63_25540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KH172YL63_25550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KH172YL63_25560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KH172YL63_25570	COG0840	transmembrane signaling receptor activity
KH172YL63_25600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KH172YL63_25610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KH172YL63_25650	COG2755	lipolytic protein G-D-S-L family
KH172YL63_25680	COG1307	EDD domain protein, DegV family
KH172YL63_25700	COG2135	peptidase activity
KH172YL63_25710	COG1272	protein, Hemolysin III
KH172YL63_25720	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KH172YL63_25730	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KH172YL63_25760	COG2521	methyltransferase
KH172YL63_25760	COG2136	Putative SAM-dependent methyltransferase
KH172YL63_25780	COG1413	lyase activity
KH172YL63_25790	COG0488	(ABC) transporter
KH172YL63_25800	COG1418	mRNA catabolic process
KH172YL63_25810	COG1307	EDD domain protein, DegV family
KH172YL63_25840	COG2226	methyltransferase
KH172YL63_25860	COG1321	iron dependent repressor
KH172YL63_25870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KH172YL63_25880	COG1321	iron dependent repressor
KH172YL63_25880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KH172YL63_25890	COG1121	(ABC) transporter
KH172YL63_25900	COG0803	Belongs to the bacterial solute-binding protein 9 family
KH172YL63_25920	COG1278	Cold shock
KH172YL63_25940	COG0328	RNA-DNA hybrid ribonuclease activity
KH172YL63_25960	COG0328	RNA-DNA hybrid ribonuclease activity
KH172YL63_26000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KH172YL63_26010	COG2897	thiosulfate sulfurtransferase activity
KH172YL63_26020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KH172YL63_26040	COG1755	Isoprenylcysteine carboxyl methyltransferase
KH172YL63_26050	COG3424	synthase
KH172YL63_26070	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_26090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KH172YL63_26100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KH172YL63_26120	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KH172YL63_26130	COG1199	ATP-dependent helicase activity
KH172YL63_26150	COG0116	Belongs to the methyltransferase superfamily
KH172YL63_26180	COG3359	exonuclease
KH172YL63_26190	COG1205	dead DEAH box helicase
KH172YL63_26190	COG1111	helicase
KH172YL63_26270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KH172YL63_26270	COG4499	WXG100 protein secretion system (Wss), protein YukC
KH172YL63_26280	COG3344	reverse transcriptase
KH172YL63_26300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KH172YL63_26310	COG3935	DnaD domain protein
KH172YL63_26320	COG0017	Asparaginyl-tRNA synthetase
KH172YL63_26330	COG0436	Aminotransferase
KH172YL63_26370	COG1199	ATP-dependent helicase activity
KH172YL63_26370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KH172YL63_26380	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KH172YL63_26390	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KH172YL63_26420	COG0617	tRNA 3'-terminal CCA addition
KH172YL63_26430	COG0438	transferase activity, transferring glycosyl groups
KH172YL63_26440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KH172YL63_26450	COG1803	Methylglyoxal synthase
KH172YL63_26470	COG1694	Mazg nucleotide pyrophosphohydrolase
KH172YL63_26480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_26490	COG2738	Putative neutral zinc metallopeptidase
KH172YL63_26510	COG4347	Protein of unknown function (DUF1405)
KH172YL63_26530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KH172YL63_26560	COG5582	Belongs to the UPF0302 family
KH172YL63_26570	COG0457	Tetratricopeptide repeat
KH172YL63_26590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KH172YL63_26600	COG0287	Prephenate dehydrogenase
KH172YL63_26610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KH172YL63_26620	COG4401	Chorismate mutase type I
KH172YL63_26630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KH172YL63_26640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KH172YL63_26650	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KH172YL63_26660	COG0105	UTP biosynthetic process
KH172YL63_26670	COG0142	geranyltranstransferase activity
KH172YL63_26680	COG2226	methyltransferase
KH172YL63_26690	COG0142	geranyltranstransferase activity
KH172YL63_26710	COG0302	gtp cyclohydrolase
KH172YL63_26720	COG0776	regulation of translation
KH172YL63_26730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KH172YL63_26760	COG1160	GTP binding
KH172YL63_26810	COG1304	FMN binding
KH172YL63_26820	COG0539	negative regulation of cytoplasmic translation
KH172YL63_26830	COG0204	Acyl-transferase
KH172YL63_26840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KH172YL63_26860	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
KH172YL63_26870	COG2959	enzyme of heme biosynthesis
KH172YL63_26880	COG3773	Cell wall hydrolase
KH172YL63_26880	COG3409	Peptidoglycan-binding domain 1 protein
KH172YL63_26890	COG2339	peptidase activity
KH172YL63_26900	COG0252	asparaginase activity
KH172YL63_26910	COG0492	ferredoxin-NADP+ reductase activity
KH172YL63_26920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KH172YL63_26940	COG0789	Transcriptional regulator
KH172YL63_26950	COG1408	metallophosphoesterase
KH172YL63_27000	COG3546	catalase activity
KH172YL63_27020	COG0438	transferase activity, transferring glycosyl groups
KH172YL63_27030	COG0671	phosphoesterase, PA-phosphatase related
KH172YL63_27040	COG1388	LysM domain
KH172YL63_27050	COG1266	CAAX protease self-immunity
KH172YL63_27060	COG0514	ATP-dependent DNA helicase (RecQ)
KH172YL63_27070	COG4955	Helix-turn-helix domain
KH172YL63_27080	COG1141	Ferredoxin
KH172YL63_27090	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KH172YL63_27120	COG1595	DNA-templated transcription, initiation
KH172YL63_27130	COG5002	protein histidine kinase activity
KH172YL63_27140	COG0745	RESPONSE REGULATOR receiver
KH172YL63_27150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KH172YL63_27160	COG1333	cytochrome c biogenesis protein
KH172YL63_27170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_27180	COG1187	pseudouridine synthase activity
KH172YL63_27190	COG0700	Nucleoside recognition
KH172YL63_27200	COG2715	membrane protein required for spore maturation
KH172YL63_27210	COG1686	Belongs to the peptidase S11 family
KH172YL63_27220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KH172YL63_27230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KH172YL63_27240	COG1547	Domain of unknown function (DUF309)
KH172YL63_27270	COG0697	spore germination
KH172YL63_27320	COG3344	reverse transcriptase
KH172YL63_27360	COG1686	Belongs to the peptidase S11 family
KH172YL63_27390	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KH172YL63_27400	COG4974	Belongs to the 'phage' integrase family
KH172YL63_27420	COG0735	belongs to the Fur family
KH172YL63_27430	COG1300	Membrane
KH172YL63_27450	COG0494	nUDIX hydrolase
KH172YL63_27460	COG0667	Aldo Keto reductase
KH172YL63_27470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KH172YL63_27470	COG0456	acetyltransferase
KH172YL63_27490	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KH172YL63_27500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KH172YL63_27510	COG0183	Belongs to the thiolase family
KH172YL63_27520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KH172YL63_27540	COG1073	alpha beta
KH172YL63_27560	COG4918	Iron-sulphur cluster biosynthesis
KH172YL63_27590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KH172YL63_27610	COG4975	Glucose uptake
KH172YL63_27640	COG0300	oxidoreductase activity
KH172YL63_27650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_27660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KH172YL63_27670	COG1902	pentaerythritol trinitrate reductase activity
KH172YL63_27700	COG1234	tRNA 3'-trailer cleavage
KH172YL63_27710	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KH172YL63_27720	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KH172YL63_27730	COG1733	regulation of RNA biosynthetic process
KH172YL63_27740	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
KH172YL63_27750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KH172YL63_27800	COG0456	acetyltransferase
KH172YL63_27800	COG0454	-acetyltransferase
KH172YL63_27810	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KH172YL63_27820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KH172YL63_27840	COG2195	Cleaves the N-terminal amino acid of tripeptides
KH172YL63_27850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KH172YL63_27860	COG0346	lactoylglutathione lyase activity
KH172YL63_27870	COG1376	ErfK ybiS ycfS ynhG family protein
KH172YL63_27880	COG4129	membrane
KH172YL63_27890	COG1126	abc transporter atp-binding protein
KH172YL63_27900	COG0765	amino acid transport
KH172YL63_27910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KH172YL63_27930	COG1703	isobutyryl-CoA mutase activity
KH172YL63_27940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KH172YL63_27940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KH172YL63_27950	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KH172YL63_27960	COG1404	Belongs to the peptidase S8 family
KH172YL63_27960	COG4412	M6 family metalloprotease domain protein
KH172YL63_27970	COG0508	dehydrogenase complex catalyzes the overall conversion of
KH172YL63_27980	COG0022	dehydrogenase e1 component
KH172YL63_27990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KH172YL63_28000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KH172YL63_28010	COG3426	butyrate kinase activity
KH172YL63_28030	COG0280	phosphate acetyltransferase
KH172YL63_28040	COG3829	transcription factor binding
KH172YL63_28040	COG3290	protein histidine kinase activity
KH172YL63_28060	COG0584	glycerophosphoryl diester phosphodiesterase
KH172YL63_28090	COG0750	zinc metalloprotease
KH172YL63_28100	COG0497	DNA recombination
KH172YL63_28110	COG1438	arginine binding
KH172YL63_28120	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KH172YL63_28130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KH172YL63_28160	COG1722	exodeoxyribonuclease VII activity
KH172YL63_28170	COG1570	exodeoxyribonuclease VII activity
KH172YL63_28180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KH172YL63_28210	COG1302	Protein conserved in bacteria
KH172YL63_28220	COG0439	Biotin carboxylase
KH172YL63_28230	COG0511	ligase activity, forming carbon-carbon bonds
KH172YL63_28310	COG3854	ATPases associated with a variety of cellular activities
KH172YL63_28320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KH172YL63_28330	COG0006	proline dipeptidase activity
KH172YL63_28340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KH172YL63_28370	COG1752	Esterase of the alpha-beta hydrolase superfamily
KH172YL63_28380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KH172YL63_28390	COG0095	Lipoate-protein ligase
KH172YL63_28400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_28410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KH172YL63_28420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KH172YL63_28430	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KH172YL63_28440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KH172YL63_28470	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KH172YL63_28520	COG4537	Required for transformation and DNA binding
KH172YL63_28540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KH172YL63_28620	COG1388	LysM domain
KH172YL63_28620	COG0791	NLP P60 protein
KH172YL63_28900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KH172YL63_28960	COG0305	Participates in initiation and elongation during chromosome replication
KH172YL63_29010	COG0419	ATPase involved in DNA repair
KH172YL63_29060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KH172YL63_29090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KH172YL63_29220	COG2002	toxin-antitoxin pair type II binding
KH172YL63_29240	COG3723	Recombinational DNA repair protein, rece pathway
KH172YL63_29250	COG3723	Recombinational DNA repair protein, rece pathway
KH172YL63_29260	COG5377	YqaJ viral recombinase family
KH172YL63_29270	COG2843	Capsule synthesis protein
KH172YL63_29300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KH172YL63_29320	COG0840	transmembrane signaling receptor activity
KH172YL63_29350	COG1393	Belongs to the ArsC family
KH172YL63_29370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_29390	COG0011	TIGRFAM Protein of
KH172YL63_29420	COG1368	sulfuric ester hydrolase activity
KH172YL63_29430	COG1940	carbohydrate kinase activity
KH172YL63_29440	COG4483	Protein conserved in bacteria
KH172YL63_29450	COG0697	spore germination
KH172YL63_29470	COG0705	Rhomboid family
KH172YL63_29470	COG0457	Tetratricopeptide repeat
KH172YL63_29500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KH172YL63_29510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KH172YL63_29530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KH172YL63_29570	COG0704	Plays a role in the regulation of phosphate uptake
KH172YL63_29580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KH172YL63_29590	COG0581	inorganic phosphate transmembrane transporter activity
KH172YL63_29600	COG0573	inorganic phosphate transmembrane transporter activity
KH172YL63_29610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KH172YL63_29630	COG0477	Major facilitator Superfamily
KH172YL63_29650	COG2839	Protein conserved in bacteria
KH172YL63_29660	COG1283	sodium-dependent phosphate transmembrane transporter activity
KH172YL63_29670	COG5521	maltodextrose utilization protein MalA
KH172YL63_29680	COG0840	transmembrane signaling receptor activity
KH172YL63_29700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KH172YL63_29710	COG4709	membrane
KH172YL63_29720	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
KH172YL63_29740	COG0735	belongs to the Fur family
KH172YL63_29750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KH172YL63_29760	COG1121	(ABC) transporter
KH172YL63_29770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_29790	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KH172YL63_29800	COG0513	Belongs to the DEAD box helicase family
KH172YL63_29820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KH172YL63_29830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KH172YL63_29840	COG2384	SAM-dependent methyltransferase
KH172YL63_29850	COG2010	Cytochrome c
KH172YL63_29860	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_29880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KH172YL63_29890	COG0358	DNA primase activity
KH172YL63_29900	COG1671	Belongs to the UPF0178 family
KH172YL63_29920	COG0517	IMP dehydrogenase activity
KH172YL63_29940	COG1381	Involved in DNA repair and RecF pathway recombination
KH172YL63_29970	COG0295	cytidine deaminase activity
KH172YL63_29980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KH172YL63_30000	COG1480	7TM receptor with intracellular HD hydrolase
KH172YL63_30010	COG1702	phosphate starvation-inducible protein PhoH
KH172YL63_30050	COG4864	UPF0365 protein
KH172YL63_30060	COG1030	water channel activity
KH172YL63_30070	COG1610	YqeY-like protein
KH172YL63_30090	COG1283	sodium-dependent phosphate transmembrane transporter activity
KH172YL63_30100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KH172YL63_30110	COG0366	Alpha amylase catalytic
KH172YL63_30120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KH172YL63_30130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KH172YL63_30160	COG0443	Heat shock 70 kDa protein
KH172YL63_30170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KH172YL63_30180	COG1420	regulation of RNA biosynthetic process
KH172YL63_30190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KH172YL63_30200	COG0481	GTPase activity
KH172YL63_30220	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_30240	COG0268	Binds directly to 16S ribosomal RNA
KH172YL63_30250	COG1466	dna polymerase III delta subunit
KH172YL63_30270	COG2333	competence protein COMEC
KH172YL63_30270	COG0658	competence protein
KH172YL63_30280	COG2131	deaminase
KH172YL63_30290	COG1596	polysaccharide export
KH172YL63_30290	COG1555	photosystem II stabilization
KH172YL63_30300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KH172YL63_30310	COG2226	methyltransferase
KH172YL63_30320	COG0799	negative regulation of ribosome biogenesis
KH172YL63_30330	COG1713	HD superfamily hydrolase involved in NAD metabolism
KH172YL63_30340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KH172YL63_30350	COG1534	Rna-binding protein
KH172YL63_30370	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KH172YL63_30380	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KH172YL63_30390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KH172YL63_30410	COG0688	phosphatidylethanolamine metabolic process
KH172YL63_30420	COG1183	phosphatidylcholine synthase activity
KH172YL63_30470	COG0626	cystathionine gamma-synthase activity
KH172YL63_30480	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KH172YL63_30490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KH172YL63_30500	COG2226	methyltransferase
KH172YL63_30530	COG0768	penicillin binding
KH172YL63_30540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KH172YL63_30550	COG0572	uridine kinase
KH172YL63_30580	COG4122	O-methyltransferase activity
KH172YL63_30590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KH172YL63_30600	COG3906	Belongs to the UPF0473 family
KH172YL63_30620	COG4472	Bacterial protein of unknown function (DUF965)
KH172YL63_30640	COG0628	permease
KH172YL63_30660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KH172YL63_30690	COG1104	cysteine desulfurase activity
KH172YL63_30700	COG1959	2 iron, 2 sulfur cluster binding
KH172YL63_30710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KH172YL63_30730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KH172YL63_30740	COG1131	(ABC) transporter
KH172YL63_30750	COG1131	(ABC) transporter
KH172YL63_30760	COG1725	Transcriptional regulator
KH172YL63_30800	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KH172YL63_30810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KH172YL63_30820	COG0124	histidyl-tRNA synthetase
KH172YL63_30840	COG4991	sh3 domain protein
KH172YL63_30840	COG3103	Sh3 type 3 domain protein
KH172YL63_30840	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_30850	COG1490	D-aminoacyl-tRNA deacylase activity
KH172YL63_30860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KH172YL63_30870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KH172YL63_30880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KH172YL63_30880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KH172YL63_30890	COG5416	Lipopolysaccharide assembly protein A domain
KH172YL63_30900	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KH172YL63_30910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KH172YL63_30910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KH172YL63_30930	COG2244	polysaccharide biosynthetic process
KH172YL63_30940	COG2323	membrane
KH172YL63_30950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KH172YL63_30970	COG1862	Preprotein translocase
KH172YL63_31000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KH172YL63_31030	COG0632	four-way junction helicase activity
KH172YL63_31070	COG1388	LysM domain
KH172YL63_31090	COG0157	Belongs to the NadC ModD family
KH172YL63_31100	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KH172YL63_31110	COG1104	cysteine desulfurase activity
KH172YL63_31120	COG1827	regulation of RNA biosynthetic process
KH172YL63_31130	COG0077	Prephenate dehydratase
KH172YL63_31140	COG4492	Belongs to the UPF0735 family
KH172YL63_31150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KH172YL63_31160	COG3290	protein histidine kinase activity
KH172YL63_31170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KH172YL63_31180	COG2868	ribosomal protein
KH172YL63_31200	COG1530	ribonuclease E activity
KH172YL63_31210	COG1994	Peptidase M50
KH172YL63_31220	COG0739	heme binding
KH172YL63_31230	COG2894	cell division
KH172YL63_31240	COG0850	regulation of cytokinetic process
KH172YL63_31250	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KH172YL63_31260	COG1792	Involved in formation and maintenance of cell shape
KH172YL63_31270	COG1077	Cell shape determining protein MreB Mrl
KH172YL63_31280	COG2003	Belongs to the UPF0758 family
KH172YL63_31350	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KH172YL63_31360	COG4969	Belongs to the N-Me-Phe pilin family
KH172YL63_31390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KH172YL63_31480	COG0285	dihydrofolate synthase activity
KH172YL63_31490	COG0525	valine-tRNA ligase activity
KH172YL63_31510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KH172YL63_31520	COG1388	LysM domain
KH172YL63_31520	COG1388	LysM domain
KH172YL63_31530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KH172YL63_31540	COG0113	porphobilinogen synthase activity
KH172YL63_31570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KH172YL63_31600	COG1126	abc transporter atp-binding protein
KH172YL63_31630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KH172YL63_31640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KH172YL63_31650	COG0470	DNA polymerase III
KH172YL63_31650	COG1067	ATP-dependent peptidase activity
KH172YL63_31670	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KH172YL63_31690	COG0544	peptidyl-prolyl cis-trans isomerase activity
KH172YL63_31710	COG0622	Phosphoesterase
KH172YL63_31720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KH172YL63_31740	COG5401	PFAM Sporulation and spore germination
KH172YL63_31760	COG1846	Transcriptional regulator
KH172YL63_31770	COG2197	response regulator
KH172YL63_31780	COG0824	Thioesterase
KH172YL63_31790	COG0737	Belongs to the 5'-nucleotidase family
KH172YL63_31800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KH172YL63_31810	COG1053	succinate dehydrogenase
KH172YL63_31820	COG2009	succinate dehydrogenase
KH172YL63_31830	COG1719	4-vinyl reductase, 4VR
KH172YL63_31850	COG0322	excinuclease ABC activity
KH172YL63_31890	COG0463	Glycosyl transferase, family 2
KH172YL63_31940	COG3118	belongs to the thioredoxin family
KH172YL63_31950	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KH172YL63_31960	COG2086	electron transfer activity
KH172YL63_31970	COG1024	Enoyl-CoA hydratase
KH172YL63_31980	COG1309	transcriptional regulator
KH172YL63_31990	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_32000	COG3766	membrane
KH172YL63_32010	COG1193	negative regulation of DNA recombination
KH172YL63_32020	COG1796	DNA polymerase
KH172YL63_32020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KH172YL63_32030	COG1286	toxin biosynthetic process
KH172YL63_32040	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KH172YL63_32050	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KH172YL63_32060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KH172YL63_32060	COG0072	phenylalanine-tRNA ligase activity
KH172YL63_32070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KH172YL63_32080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KH172YL63_32100	COG1335	isochorismatase
KH172YL63_32110	COG1363	Peptidase, m42
KH172YL63_32140	COG0398	Pfam SNARE associated Golgi protein
KH172YL63_32160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KH172YL63_32180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KH172YL63_32190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KH172YL63_32210	COG1484	DNA-dependent DNA replication
KH172YL63_32220	COG3611	Membrane attachment protein
KH172YL63_32230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KH172YL63_32260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KH172YL63_32280	COG0237	dephospho-CoA kinase activity
KH172YL63_32290	COG1971	Probably functions as a manganese efflux pump
KH172YL63_32300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KH172YL63_32310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KH172YL63_32310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KH172YL63_32320	COG0330	HflC and HflK could
KH172YL63_32330	COG0330	HflC and HflK could
KH172YL63_32340	COG5002	protein histidine kinase activity
KH172YL63_32350	COG0745	RESPONSE REGULATOR receiver
KH172YL63_32400	COG0538	isocitrate dehydrogenase activity
KH172YL63_32410	COG0372	Belongs to the citrate synthase family
KH172YL63_32420	COG0628	permease
KH172YL63_32430	COG3030	protein affecting phage T7 exclusion by the F plasmid
KH172YL63_32450	COG0205	6-phosphofructokinase activity
KH172YL63_32460	COG0825	malonyl-CoA metabolic process
KH172YL63_32470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KH172YL63_32480	COG1725	Transcriptional regulator
KH172YL63_32490	COG0281	malic enzyme
KH172YL63_32500	COG0587	DNA-directed DNA polymerase activity
KH172YL63_32560	COG1011	Hydrolase
KH172YL63_32590	COG1595	DNA-templated transcription, initiation
KH172YL63_32640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KH172YL63_32690	COG2267	carboxylic ester hydrolase activity
KH172YL63_32700	COG2329	Antibiotic biosynthesis monooxygenase
KH172YL63_32750	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KH172YL63_32770	COG4109	DRTGG domain
KH172YL63_32780	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_32940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KH172YL63_32950	COG0596	Alpha beta hydrolase
KH172YL63_32990	COG1879	ABC-type sugar transport system periplasmic component
KH172YL63_33000	COG1172	Belongs to the binding-protein-dependent transport system permease family
KH172YL63_33010	COG1129	ABC transporter
KH172YL63_33020	COG1869	D-ribose catabolic process
KH172YL63_33030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KH172YL63_33040	COG1609	Transcriptional regulator
KH172YL63_33060	COG2814	Major facilitator Superfamily
KH172YL63_33070	COG1733	regulation of RNA biosynthetic process
KH172YL63_33080	COG0656	L-ascorbic acid biosynthetic process
KH172YL63_33090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KH172YL63_33140	COG1464	Belongs to the NlpA lipoprotein family
KH172YL63_33150	COG2011	ABC-type metal ion transport system permease component
KH172YL63_33170	COG1285	pathogenesis
KH172YL63_33190	COG3220	belongs to the UPF0276 family
KH172YL63_33220	COG2153	protein acetylation
KH172YL63_33260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KH172YL63_33280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KH172YL63_33310	COG1609	Transcriptional regulator
KH172YL63_33450	COG0842	Transport permease protein
KH172YL63_33460	COG0842	Transport permease protein
KH172YL63_33460	COG1511	domain protein
KH172YL63_33470	COG1131	(ABC) transporter
KH172YL63_33480	COG2197	response regulator
KH172YL63_33490	COG4585	Histidine kinase
KH172YL63_33540	COG3557	Belongs to the UPF0374 family
KH172YL63_33580	COG0667	Aldo Keto reductase
KH172YL63_33590	COG2188	Transcriptional regulator
KH172YL63_33630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KH172YL63_33750	COG0165	Argininosuccinate lyase
KH172YL63_33760	COG0137	argininosuccinate synthase activity
KH172YL63_33780	COG2217	Heavy metal translocating P-type atpase
KH172YL63_33790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KH172YL63_33800	COG0827	DNA restriction-modification system
KH172YL63_33810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KH172YL63_33820	COG3874	Sporulation protein YtfJ
KH172YL63_33840	COG1714	RDD family
KH172YL63_33850	COG0616	signal peptide processing
KH172YL63_33860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KH172YL63_33880	COG2962	Rard protein
KH172YL63_33890	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KH172YL63_33920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KH172YL63_33940	COG0301	tRNA thio-modification
KH172YL63_33950	COG1104	cysteine desulfurase activity
KH172YL63_33960	COG1114	Component of the transport system for branched-chain amino acids
KH172YL63_33970	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KH172YL63_33980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KH172YL63_33990	COG1309	transcriptional regulator
KH172YL63_34000	COG1956	GAF domain-containing protein
KH172YL63_34030	COG2199	diguanylate cyclase activity
KH172YL63_34030	COG2203	Gaf domain
KH172YL63_34040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KH172YL63_34090	COG0747	negative chemotaxis
KH172YL63_34130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KH172YL63_34160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KH172YL63_34170	COG0454	-acetyltransferase
KH172YL63_34180	COG0517	IMP dehydrogenase activity
KH172YL63_34190	COG0123	including yeast histone deacetylase and acetoin utilization protein
KH172YL63_34210	COG3383	formate dehydrogenase (NAD+) activity
KH172YL63_34220	COG2427	Protein of unknown function (DUF1641)
KH172YL63_34240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KH172YL63_34260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KH172YL63_34260	COG1605	Chorismate mutase
KH172YL63_34270	COG0849	cell division
KH172YL63_34310	COG4980	gas vesicle protein
KH172YL63_34330	COG2309	aminopeptidase activity
KH172YL63_34340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KH172YL63_34370	COG1674	ftsk spoiiie
KH172YL63_34380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KH172YL63_34390	COG4848	Belongs to the UPF0354 family
KH172YL63_34400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_34450	COG3104	oligopeptide transport
KH172YL63_34470	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KH172YL63_34480	COG1363	Peptidase, m42
KH172YL63_34500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_34510	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KH172YL63_34530	COG0510	thiamine kinase activity
KH172YL63_34540	COG1523	belongs to the glycosyl hydrolase 13 family
KH172YL63_34550	COG1597	lipid kinase activity
KH172YL63_34580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KH172YL63_34600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KH172YL63_34610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KH172YL63_34620	COG1349	DNA-binding transcription factor activity
KH172YL63_34630	COG1187	pseudouridine synthase activity
KH172YL63_34640	COG2244	polysaccharide biosynthetic process
KH172YL63_34650	COG2081	HI0933 family
KH172YL63_34670	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_34680	COG0495	leucyl-tRNA aminoacylation
KH172YL63_34690	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_34700	COG2610	gluconate transmembrane transporter activity
KH172YL63_34710	COG3829	transcription factor binding
KH172YL63_34710	COG3290	protein histidine kinase activity
KH172YL63_34720	COG4297	protein containing double-stranded beta helix domain
KH172YL63_34730	COG2814	Major facilitator Superfamily
KH172YL63_34760	COG1242	4 iron, 4 sulfur cluster binding
KH172YL63_34770	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KH172YL63_34780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KH172YL63_34810	COG2267	carboxylic ester hydrolase activity
KH172YL63_34820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KH172YL63_34830	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KH172YL63_34840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KH172YL63_34870	COG1268	BioY protein
KH172YL63_34900	COG1506	peptidase
KH172YL63_34910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KH172YL63_34920	COG1116	anion transmembrane transporter activity
KH172YL63_34930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KH172YL63_34960	COG4824	toxin secretion phage lysis holin
KH172YL63_35000	COG1854	S-ribosylhomocysteine lyase activity
KH172YL63_35010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KH172YL63_35020	COG0803	Belongs to the bacterial solute-binding protein 9 family
KH172YL63_35020	COG3443	Belongs to the bacterial solute-binding protein 9 family
KH172YL63_35030	COG1271	oxidase subunit
KH172YL63_35040	COG1294	oxidase, subunit
KH172YL63_35050	COG0300	oxidoreductase activity
KH172YL63_35070	COG3620	sequence-specific DNA binding
KH172YL63_35080	COG4948	Mandelate Racemase Muconate Lactonizing
KH172YL63_35090	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_35100	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KH172YL63_35110	COG0596	Alpha beta hydrolase
KH172YL63_35120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KH172YL63_35130	COG1169	isochorismate synthase
KH172YL63_35140	COG1575	Belongs to the MenA family. Type 1 subfamily
KH172YL63_35150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KH172YL63_35160	COG0058	SHG alpha-glucan phosphorylase activity
KH172YL63_35170	COG0297	glycogen (starch) synthase activity
KH172YL63_35180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KH172YL63_35220	COG1247	-acetyltransferase
KH172YL63_35240	COG1285	pathogenesis
KH172YL63_35250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KH172YL63_35250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KH172YL63_35250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KH172YL63_35260	COG1105	Belongs to the carbohydrate kinase PfkB family
KH172YL63_35270	COG1349	DNA-binding transcription factor activity
KH172YL63_35280	COG1368	sulfuric ester hydrolase activity
KH172YL63_35310	COG0561	phosphatase activity
KH172YL63_35320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KH172YL63_35340	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KH172YL63_35350	COG0363	glucosamine-6-phosphate deaminase activity
KH172YL63_35360	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KH172YL63_35370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KH172YL63_35370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KH172YL63_35410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KH172YL63_35420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KH172YL63_35450	COG1979	alcohol dehydrogenase
KH172YL63_35460	COG2155	Conserved Protein
KH172YL63_35470	COG1012	belongs to the aldehyde dehydrogenase family
KH172YL63_35480	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KH172YL63_35490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KH172YL63_35500	COG1012	belongs to the aldehyde dehydrogenase family
KH172YL63_35510	COG3829	transcription factor binding
KH172YL63_35520	COG0753	catalase activity
KH172YL63_35540	COG1012	belongs to the aldehyde dehydrogenase family
KH172YL63_35560	COG3344	reverse transcriptase
KH172YL63_35570	COG1098	S1 RNA binding domain
KH172YL63_35590	COG1595	DNA-templated transcription, initiation
KH172YL63_35610	COG0733	neurotransmitter:sodium symporter activity
KH172YL63_35630	COG0436	Aminotransferase
KH172YL63_35640	COG1522	sequence-specific DNA binding
KH172YL63_35650	COG2267	carboxylic ester hydrolase activity
KH172YL63_35670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KH172YL63_35680	COG2032	superoxide dismutase activity
KH172YL63_35700	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KH172YL63_35720	COG5018	Exonuclease
KH172YL63_35730	COG2814	Major facilitator Superfamily
KH172YL63_35740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KH172YL63_35770	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KH172YL63_35770	COG2111	Na H antiporter
KH172YL63_35780	COG2111	Na H antiporter
KH172YL63_35790	COG1006	Multisubunit Na H antiporter MnhC subunit
KH172YL63_35800	COG0651	ATP synthesis coupled electron transport
KH172YL63_35810	COG1863	multisubunit Na H antiporter MnhE subunit
KH172YL63_35820	COG2212	antiporter activity
KH172YL63_35840	COG4876	unkown
KH172YL63_35850	COG2050	protein possibly involved in aromatic compounds catabolism
KH172YL63_35880	COG2056	Na+-H+ antiporter family
KH172YL63_35890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KH172YL63_35900	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KH172YL63_35920	COG3584	3D domain protein
KH172YL63_35950	COG1252	NADH dehydrogenase
KH172YL63_35970	COG2808	Putative FMN-binding domain
KH172YL63_35980	COG0702	epimerase
KH172YL63_35990	COG0316	Belongs to the HesB IscA family
KH172YL63_36020	COG1252	NADH dehydrogenase
KH172YL63_36030	COG4837	Protein of unknown function (DUF1462)
KH172YL63_36040	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KH172YL63_36050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KH172YL63_36060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KH172YL63_36070	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KH172YL63_36090	COG0647	UMP catabolic process
KH172YL63_36100	COG2445	Protein of unknown function DUF86
KH172YL63_36140	COG4470	Protein conserved in bacteria
KH172YL63_36170	COG0739	heme binding
KH172YL63_36180	COG0733	neurotransmitter:sodium symporter activity
KH172YL63_36190	COG1757	Na H antiporter
KH172YL63_36220	COG3377	Domain of unknown function (DUF1805)
KH172YL63_36230	COG0737	Belongs to the 5'-nucleotidase family
KH172YL63_36240	COG0730	response to heat
KH172YL63_36250	COG1801	Protein of unknown function DUF72
KH172YL63_36260	COG0719	Fe-S assembly protein
KH172YL63_36270	COG0822	iron-sulfur transferase activity
KH172YL63_36280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KH172YL63_36290	COG0719	Fe-S assembly protein
KH172YL63_36300	COG0396	ATPase activity
KH172YL63_36320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KH172YL63_36330	COG1464	Belongs to the NlpA lipoprotein family
KH172YL63_36340	COG2011	ABC-type metal ion transport system permease component
KH172YL63_36350	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KH172YL63_36370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_36380	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KH172YL63_36400	COG0509	glycine decarboxylation via glycine cleavage system
KH172YL63_36410	COG1393	Belongs to the ArsC family
KH172YL63_36440	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_36450	COG0183	Belongs to the thiolase family
KH172YL63_36460	COG1250	3-hydroxyacyl-CoA dehydrogenase
KH172YL63_36460	COG1024	Enoyl-CoA hydratase
KH172YL63_36480	COG2364	Membrane
KH172YL63_36490	COG0385	Bile acid
KH172YL63_36520	COG0506	proline dehydrogenase activity
KH172YL63_36550	COG5577	PFAM Coat F domain
KH172YL63_36580	COG1120	ATPase activity
KH172YL63_36590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KH172YL63_36600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KH172YL63_36610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KH172YL63_36650	COG0673	inositol 2-dehydrogenase activity
KH172YL63_36660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_36700	COG1785	Belongs to the alkaline phosphatase family
KH172YL63_36710	COG1834	amidinotransferase
KH172YL63_36720	COG0318	PFAM AMP-dependent synthetase and ligase
KH172YL63_36760	COG1979	alcohol dehydrogenase
KH172YL63_36770	COG0583	DNA-binding transcription factor activity
KH172YL63_36780	COG0655	NAD(P)H dehydrogenase (quinone) activity
KH172YL63_36820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KH172YL63_36830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KH172YL63_36840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KH172YL63_36840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KH172YL63_36850	COG5002	protein histidine kinase activity
KH172YL63_36940	COG0716	FMN binding
KH172YL63_36950	COG2814	Major facilitator Superfamily
KH172YL63_36980	COG3227	Zinc metalloprotease (Elastase)
KH172YL63_37010	COG1113	amino acid transport
KH172YL63_37020	COG3403	YqcI/YcgG family
KH172YL63_37030	COG1280	lysine exporter protein (LysE YggA)
KH172YL63_37040	COG5577	PFAM Coat F domain
KH172YL63_37060	COG0460	homoserine dehydrogenase
KH172YL63_37080	COG1027	Aspartate ammonia-lyase
KH172YL63_37100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KH172YL63_37120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KH172YL63_37160	COG2217	Heavy metal translocating P-type atpase
KH172YL63_37180	COG3682	Transcriptional regulator
KH172YL63_37190	COG1388	LysM domain
KH172YL63_37200	COG5002	protein histidine kinase activity
KH172YL63_37210	COG0745	RESPONSE REGULATOR receiver
KH172YL63_37240	COG0701	Predicted permease
KH172YL63_37260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KH172YL63_37270	COG0557	exoribonuclease II activity
KH172YL63_37280	COG1647	Serine aminopeptidase, S33
KH172YL63_37290	COG3344	reverse transcriptase
KH172YL63_37300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KH172YL63_37310	COG0148	phosphopyruvate hydratase activity
KH172YL63_37380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KH172YL63_37390	COG0840	transmembrane signaling receptor activity
KH172YL63_37440	COG5002	protein histidine kinase activity
KH172YL63_37450	COG0745	RESPONSE REGULATOR receiver
KH172YL63_37500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KH172YL63_37510	COG1481	regulation of sporulation
KH172YL63_37520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KH172YL63_37530	COG1660	Displays ATPase and GTPase activities
KH172YL63_37540	COG1051	belongs to the nudix hydrolase family
KH172YL63_37580	COG0492	ferredoxin-NADP+ reductase activity
KH172YL63_37590	COG0457	Tetratricopeptide repeat
KH172YL63_37600	COG0140	phosphoribosyl-ATP diphosphatase activity
KH172YL63_37600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KH172YL63_37610	COG0107	imidazoleglycerol-phosphate synthase activity
KH172YL63_37620	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KH172YL63_37630	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KH172YL63_37640	COG0131	Imidazoleglycerol-phosphate dehydratase
KH172YL63_37650	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KH172YL63_37660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KH172YL63_37670	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KH172YL63_37680	COG0110	maltose O-acetyltransferase activity
KH172YL63_37690	COG0546	phosphoglycolate phosphatase activity
KH172YL63_37700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KH172YL63_37720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KH172YL63_37740	COG1950	PFAM Membrane protein of
KH172YL63_37750	COG1983	PspC domain protein
KH172YL63_37760	COG3595	metallopeptidase activity
KH172YL63_37780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KH172YL63_37790	COG0556	nucleotide-excision repair
KH172YL63_37810	COG4897	Protein conserved in bacteria
KH172YL63_37830	COG0596	Alpha beta hydrolase
KH172YL63_37840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KH172YL63_37860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KH172YL63_37870	COG0569	domain protein
KH172YL63_37890	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KH172YL63_37900	COG1216	Glycosyl transferase, family 2
KH172YL63_37920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KH172YL63_37950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KH172YL63_37960	COG0297	glycogen (starch) synthase activity
KH172YL63_37990	COG4464	protein tyrosine phosphatase activity
KH172YL63_38010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KH172YL63_38020	COG0793	Belongs to the peptidase S41A family
KH172YL63_38020	COG3409	Peptidoglycan-binding domain 1 protein
KH172YL63_38030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KH172YL63_38050	COG0626	cystathionine gamma-synthase activity
KH172YL63_38070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KH172YL63_38100	COG3344	reverse transcriptase
KH172YL63_38110	COG0739	heme binding
KH172YL63_38120	COG2177	Part of the ABC transporter FtsEX involved in
KH172YL63_38130	COG2884	Cell division ATP-binding protein ftsE
KH172YL63_38150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KH172YL63_38160	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KH172YL63_38170	COG0653	protein targeting
KH172YL63_38180	COG1405	negative regulation of cell septum assembly
KH172YL63_38180	COG3012	SEC-C Motif Domain Protein
KH172YL63_38270	COG1516	flagellar protein fliS
KH172YL63_38280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KH172YL63_38290	COG1334	flagellar protein FlaG
KH172YL63_38310	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KH172YL63_38320	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KH172YL63_38340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KH172YL63_38350	COG4786	Flagellar basal body rod
KH172YL63_38350	COG1256	bacterial-type flagellum assembly
KH172YL63_38370	COG2747	anti-sigma28 factor FlgM
KH172YL63_38400	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KH172YL63_38410	COG1307	EDD domain protein, DegV family
KH172YL63_38440	COG1847	R3H domain protein
KH172YL63_38450	COG2208	phosphoserine phosphatase activity
KH172YL63_38500	COG0300	oxidoreductase activity
KH172YL63_38540	COG3300	MHYT domain
KH172YL63_38540	COG5001	Diguanylate cyclase
KH172YL63_38580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KH172YL63_38630	COG0346	lactoylglutathione lyase activity
KH172YL63_38650	COG1227	inorganic diphosphatase activity
KH172YL63_38680	COG0768	penicillin binding
KH172YL63_38710	COG0791	NLP P60 protein
KH172YL63_38710	COG1388	LysM domain
KH172YL63_38720	COG3850	Histidine kinase
KH172YL63_38720	COG5002	protein histidine kinase activity
KH172YL63_38760	COG1263	PTS System
KH172YL63_38760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KH172YL63_38770	COG0366	Alpha amylase catalytic
KH172YL63_38820	COG2188	Transcriptional regulator
KH172YL63_38830	COG2197	response regulator
KH172YL63_38840	COG4585	Histidine kinase
KH172YL63_38850	COG1739	Uncharacterized protein family UPF0029
KH172YL63_38860	COG1316	TRANSCRIPTIONal
KH172YL63_38870	COG0438	transferase activity, transferring glycosyl groups
KH172YL63_38890	COG2244	polysaccharide biosynthetic process
KH172YL63_38900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KH172YL63_38910	COG1215	transferase activity, transferring glycosyl groups
KH172YL63_38940	COG3307	-O-antigen
KH172YL63_38960	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KH172YL63_38970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KH172YL63_38980	COG2385	sporulation resulting in formation of a cellular spore
KH172YL63_38980	COG2247	cell wall binding repeat
KH172YL63_38980	COG2385	sporulation resulting in formation of a cellular spore
KH172YL63_38980	COG2247	cell wall binding repeat
KH172YL63_39000	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_39020	COG1404	Belongs to the peptidase S8 family
KH172YL63_39040	COG2247	cell wall binding repeat
KH172YL63_39040	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_39050	COG2247	cell wall binding repeat
KH172YL63_39050	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_39060	COG2247	cell wall binding repeat
KH172YL63_39060	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_39090	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_39090	COG2247	cell wall binding repeat
KH172YL63_39130	COG0438	transferase activity, transferring glycosyl groups
KH172YL63_39150	COG0737	Belongs to the 5'-nucleotidase family
KH172YL63_39180	COG1464	Belongs to the NlpA lipoprotein family
KH172YL63_39190	COG2011	ABC-type metal ion transport system permease component
KH172YL63_39200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KH172YL63_39230	COG1511	domain protein
KH172YL63_39240	COG1309	transcriptional regulator
KH172YL63_39250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KH172YL63_39270	COG1595	DNA-templated transcription, initiation
KH172YL63_39280	COG5001	Diguanylate cyclase
KH172YL63_39280	COG3300	MHYT domain
KH172YL63_39290	COG3852	Histidine kinase
KH172YL63_39310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KH172YL63_39320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KH172YL63_39340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KH172YL63_39340	COG1263	PTS System
KH172YL63_39350	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KH172YL63_39370	COG1404	Belongs to the peptidase S8 family
KH172YL63_39410	COG4974	Belongs to the 'phage' integrase family
KH172YL63_39440	COG2610	gluconate transmembrane transporter activity
KH172YL63_39610	COG1316	TRANSCRIPTIONal
KH172YL63_39660	COG5444	nuclease activity
KH172YL63_39700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KH172YL63_39720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KH172YL63_39720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KH172YL63_39720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KH172YL63_39730	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KH172YL63_39730	COG3711	transcriptional antiterminator
KH172YL63_39760	COG1621	beta-fructofuranosidase activity
KH172YL63_39770	COG1929	Belongs to the glycerate kinase type-1 family
KH172YL63_39790	COG0383	alpha-mannosidase activity
KH172YL63_39800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KH172YL63_39800	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KH172YL63_39800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KH172YL63_39810	COG1737	Transcriptional regulator
KH172YL63_39820	COG1482	cell wall glycoprotein biosynthetic process
KH172YL63_39830	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KH172YL63_39840	COG1940	carbohydrate kinase activity
KH172YL63_39850	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
KH172YL63_39870	COG1653	transport
KH172YL63_39880	COG1175	transmembrane transport
KH172YL63_39890	COG0395	ABC-type sugar transport system, permease component
KH172YL63_39920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KH172YL63_39930	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KH172YL63_39980	COG0438	transferase activity, transferring glycosyl groups
KH172YL63_40040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KH172YL63_40050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KH172YL63_40070	COG4464	protein tyrosine phosphatase activity
KH172YL63_40080	COG0489	protein tyrosine kinase activity
KH172YL63_40090	COG3944	biosynthesis protein
KH172YL63_40110	COG1388	LysM domain
KH172YL63_40110	COG0791	NLP P60 protein
KH172YL63_40120	COG1316	TRANSCRIPTIONal
KH172YL63_40170	COG0010	Belongs to the arginase family
KH172YL63_40180	COG1228	amidohydrolase
KH172YL63_40190	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KH172YL63_40200	COG2986	histidine ammonia-lyase
KH172YL63_40230	COG1943	Transposase
KH172YL63_40290	COG1785	Belongs to the alkaline phosphatase family
KH172YL63_40300	COG4715	Zinc finger, swim domain protein
KH172YL63_40310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KH172YL63_40330	COG0629	single-stranded DNA binding
KH172YL63_40350	COG1396	sequence-specific DNA binding
KH172YL63_40410	COG4786	Flagellar basal body rod
KH172YL63_40420	COG4786	Flagellar basal body rod
KH172YL63_40430	COG1077	Cell shape determining protein MreB Mrl
KH172YL63_40440	COG1609	Transcriptional regulator
KH172YL63_40450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KH172YL63_40480	COG0739	heme binding
KH172YL63_40500	COG2385	sporulation resulting in formation of a cellular spore
KH172YL63_40530	COG4836	Membrane
KH172YL63_40570	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KH172YL63_40580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KH172YL63_40590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KH172YL63_40600	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KH172YL63_40610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KH172YL63_40620	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KH172YL63_40630	COG0356	it plays a direct role in the translocation of protons across the membrane
KH172YL63_40660	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KH172YL63_40670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KH172YL63_40690	COG0698	ribose 5-phosphate isomerase
KH172YL63_40700	COG0840	transmembrane signaling receptor activity
KH172YL63_40730	COG1971	Probably functions as a manganese efflux pump
KH172YL63_40740	COG0009	L-threonylcarbamoyladenylate synthase
KH172YL63_40780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KH172YL63_40800	COG1435	thymidine kinase activity
KH172YL63_40820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KH172YL63_40830	COG1494	fructose-1,6-bisphosphatase
KH172YL63_40840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KH172YL63_40860	COG0191	fructose-bisphosphate aldolase activity
KH172YL63_40870	COG2204	response regulator
KH172YL63_40880	COG4821	SIS domain
KH172YL63_40890	COG0504	CTP synthase activity
KH172YL63_40930	COG1703	isobutyryl-CoA mutase activity
KH172YL63_40930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KH172YL63_40930	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KH172YL63_40950	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_40960	COG1960	acyl-CoA dehydrogenase activity
KH172YL63_40970	COG1250	3-hydroxyacyl-CoA dehydrogenase
KH172YL63_40980	COG0183	Belongs to the thiolase family
KH172YL63_40990	COG2181	nitrate reductase activity
KH172YL63_40990	COG0247	lactate metabolic process
KH172YL63_41000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KH172YL63_41010	COG4294	response to UV
KH172YL63_41040	COG0018	arginyl-trna synthetase
KH172YL63_41050	COG4506	Protein conserved in bacteria
KH172YL63_41060	COG0010	Belongs to the arginase family
KH172YL63_41070	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KH172YL63_41080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KH172YL63_41100	COG1994	Peptidase M50
KH172YL63_41130	COG3465	dGTPase activity
KH172YL63_41140	COG1078	dGTPase activity
KH172YL63_41180	COG0280	phosphate acetyltransferase
KH172YL63_41200	COG3773	Cell wall hydrolase
KH172YL63_41220	COG2363	Small membrane protein
KH172YL63_41240	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KH172YL63_41270	COG0351	phosphomethylpyrimidine kinase
KH172YL63_41280	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KH172YL63_41300	COG1131	(ABC) transporter
KH172YL63_41350	COG1191	sigma factor activity
KH172YL63_41380	COG0860	N-Acetylmuramoyl-L-alanine amidase
KH172YL63_41420	COG0561	phosphatase activity
KH172YL63_41440	COG2031	fatty acid transporter
KH172YL63_41470	COG4191	Histidine kinase
KH172YL63_41530	COG1620	l-lactate permease
KH172YL63_41550	COG2318	DinB family
KH172YL63_41560	COG2364	Membrane
KH172YL63_41580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KH172YL63_41590	COG0723	plastoquinol--plastocyanin reductase activity
KH172YL63_41590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KH172YL63_41620	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KH172YL63_41620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KH172YL63_41680	COG3835	regulator
KH172YL63_41690	COG1929	Belongs to the glycerate kinase type-1 family
KH172YL63_41700	COG2610	gluconate transmembrane transporter activity
KH172YL63_41730	COG1028	Short-chain dehydrogenase reductase Sdr
KH172YL63_41740	COG2610	gluconate transmembrane transporter activity
KH172YL63_41750	COG0583	DNA-binding transcription factor activity
KH172YL63_41770	COG1511	domain protein
KH172YL63_41780	COG0433	COG0433 Predicted ATPase
KH172YL63_41780	COG1674	ftsk spoiiie
KH172YL63_41790	COG4499	WXG100 protein secretion system (Wss), protein YukC
KH172YL63_41800	COG5417	Belongs to the EsaB family
KH172YL63_41810	COG4842	Belongs to the WXG100 family
KH172YL63_41830	COG0745	RESPONSE REGULATOR receiver
KH172YL63_41840	COG0642	Histidine kinase
KH172YL63_41850	COG1136	(ABC) transporter
KH172YL63_41860	COG0577	efflux transmembrane transporter activity
KH172YL63_41960	COG2814	Major facilitator Superfamily
KH172YL63_41970	COG4682	membrane
KH172YL63_41980	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KH172YL63_41990	COG1064	alcohol dehydrogenase
KH172YL63_42000	COG3300	MHYT domain
KH172YL63_42000	COG5001	Diguanylate cyclase
KH172YL63_42060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KH172YL63_42070	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KH172YL63_42080	COG4853	Protein conserved in bacteria
KH172YL63_42090	COG4863	YycH protein
KH172YL63_42100	COG5002	protein histidine kinase activity
KH172YL63_42110	COG0745	RESPONSE REGULATOR receiver
KH172YL63_42120	COG0739	heme binding
KH172YL63_42150	COG0754	glutathionylspermidine amidase activity
KH172YL63_42180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KH172YL63_42190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KH172YL63_42200	COG1132	(ABC) transporter
KH172YL63_42210	COG0305	Participates in initiation and elongation during chromosome replication
KH172YL63_42220	COG0359	binds to the 23S rRNA
KH172YL63_42230	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KH172YL63_42240	COG4241	membrane
KH172YL63_42250	COG0840	transmembrane signaling receptor activity
KH172YL63_42260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KH172YL63_42280	COG0360	Binds together with S18 to 16S ribosomal RNA
KH172YL63_42290	COG0012	GTP binding
KH172YL63_42300	COG4481	Protein conserved in bacteria
KH172YL63_42310	COG0668	transmembrane transport
KH172YL63_42340	COG1475	DNA binding
KH172YL63_42350	COG1192	Involved in chromosome partitioning
KH172YL63_42360	COG1475	DNA binding
KH172YL63_42370	COG0357	Ribosomal RNA small subunit methyltransferase G
KH172YL63_42380	COG0445	tRNA wobble uridine modification
KH172YL63_42390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KH172YL63_42400	COG1847	R3H domain protein
KH172YL63_42420	COG0594	ribonuclease P activity
KH172YL63_42430	COG0230	Belongs to the bacterial ribosomal protein bL34 family