locus-tag	class	description
G4O42_00010	COG0592	DNA-directed DNA polymerase activity
G4O42_00015	COG2501	S4 domain
G4O42_00030	COG0187	DNA topoisomerase II activity
G4O42_00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4O42_00070	COG0516	GMP reductase activity
G4O42_00070	COG0517	IMP dehydrogenase activity
G4O42_00075	COG1686	Belongs to the peptidase S11 family
G4O42_00095	COG1929	Belongs to the glycerate kinase type-1 family
G4O42_00105	COG1428	Deoxynucleoside kinase
G4O42_00110	COG1428	Deoxynucleoside kinase
G4O42_00115	COG3858	chitin binding
G4O42_00115	COG1388	LysM domain
G4O42_00120	COG1335	isochorismatase
G4O42_00125	COG0590	tRNA wobble adenosine to inosine editing
G4O42_00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G4O42_00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G4O42_00145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G4O42_00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
G4O42_00195	COG3853	Toxic anion resistance protein (TelA)
G4O42_00200	COG1982	Orn Lys Arg decarboxylase major
G4O42_00210	COG3870	Protein conserved in bacteria
G4O42_00215	COG1728	Protein conserved in bacteria
G4O42_00220	COG0470	DNA polymerase III
G4O42_00225	COG1774	PSP1 C-terminal conserved region
G4O42_00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G4O42_00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G4O42_00250	COG2002	toxin-antitoxin pair type II binding
G4O42_00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_00260	COG0084	hydrolase, TatD family'
G4O42_00265	COG3584	3D domain protein
G4O42_00265	COG3583	domain protein
G4O42_00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G4O42_00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G4O42_00285	COG4466	Protein conserved in bacteria
G4O42_00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G4O42_00305	COG0251	oxidation-reduction process
G4O42_00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G4O42_00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G4O42_00345	COG2002	toxin-antitoxin pair type II binding
G4O42_00350	COG2244	polysaccharide biosynthetic process
G4O42_00355	COG3956	TIGRFAM MazG family protein
G4O42_00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G4O42_00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G4O42_00380	COG1098	S1 RNA binding domain
G4O42_00395	COG2208	phosphoserine phosphatase activity
G4O42_00400	COG2304	oxidoreductase activity
G4O42_00405	COG0515	serine threonine protein kinase
G4O42_00410	COG0037	tRNA processing
G4O42_00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G4O42_00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4O42_00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4O42_00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G4O42_00450	COG0512	Glutamine amidotransferase of anthranilate synthase
G4O42_00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G4O42_00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G4O42_00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G4O42_00475	COG1396	sequence-specific DNA binding
G4O42_00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G4O42_00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G4O42_00565	COG4463	regulation of RNA biosynthetic process
G4O42_00570	COG3880	PFAM UvrB UvrC protein
G4O42_00580	COG0542	response to heat
G4O42_00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G4O42_00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G4O42_00595	COG4956	integral membrane protein (PIN domain superfamily)
G4O42_00615	COG1045	serine acetyltransferase
G4O42_00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
G4O42_00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4O42_00635	COG3688	RNA-binding protein containing a PIN domain
G4O42_00640	COG1595	DNA-templated transcription, initiation
G4O42_00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G4O42_00655	COG0250	Participates in transcription elongation, termination and antitermination
G4O42_00680	COG2813	Specifically methylates the guanine in position
G4O42_00695	COG1358	cellular component organization or biogenesis
G4O42_00720	COG0596	Alpha beta hydrolase
G4O42_00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G4O42_00830	COG0201	protein transport
G4O42_00840	COG0024	Methionine aminopeptidase
G4O42_00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G4O42_00880	COG1122	ATPase activity
G4O42_00885	COG1122	ATPase activity
G4O42_00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G4O42_00910	COG2226	methyltransferase
G4O42_00915	COG2318	DinB family
G4O42_00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_00930	COG0489	protein tyrosine kinase activity
G4O42_00940	COG2194	sulfuric ester hydrolase activity
G4O42_00945	COG0726	polysaccharide deacetylase
G4O42_01005	COG0738	Major facilitator superfamily
G4O42_01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4O42_01020	COG1063	alcohol dehydrogenase
G4O42_01025	COG0659	secondary active sulfate transmembrane transporter activity
G4O42_01030	COG0385	Bile acid
G4O42_01035	COG2819	hydrolase of the alpha beta superfamily
G4O42_01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_01055	COG2207	Transcriptional regulator
G4O42_01060	COG3876	Protein conserved in bacteria
G4O42_01065	COG1472	Belongs to the glycosyl hydrolase 3 family
G4O42_01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_01075	COG1263	PTS System
G4O42_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_01090	COG1683	Conserved Protein
G4O42_01120	COG1595	DNA-templated transcription, initiation
G4O42_01125	COG5662	AntiSigma factor
G4O42_01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G4O42_01135	COG4856	YbbR-like protein
G4O42_01165	COG5002	protein histidine kinase activity
G4O42_01170	COG1136	(ABC) transporter
G4O42_01175	COG0577	efflux transmembrane transporter activity
G4O42_01195	COG1346	cytolysis
G4O42_01200	COG1380	Effector of murein hydrolase LrgA
G4O42_01205	COG1846	Transcriptional regulator
G4O42_01210	COG1113	amino acid transport
G4O42_01215	COG1011	Hydrolase
G4O42_01220	COG4585	Histidine kinase
G4O42_01225	COG2197	response regulator
G4O42_01230	COG1131	(ABC) transporter
G4O42_01270	COG0531	amino acid
G4O42_01275	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
G4O42_01290	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_01295	COG2271	Major facilitator Superfamily
G4O42_01305	COG2368	4-hydroxyphenylacetate
G4O42_01315	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_01330	COG1397	ADP-ribosylglycohydrolase
G4O42_01335	COG5444	nuclease activity
G4O42_01345	COG0371	Dehydrogenase
G4O42_01355	COG1183	phosphatidylcholine synthase activity
G4O42_01360	COG0586	Pfam SNARE associated Golgi protein
G4O42_01365	COG0688	phosphatidylethanolamine metabolic process
G4O42_01380	COG1301	dicarboxylic acid transport
G4O42_01385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_01390	COG0833	amino acid
G4O42_01395	COG2040	homocysteine
G4O42_01400	COG1115	amino acid carrier protein
G4O42_01405	COG2066	Belongs to the glutaminase family
G4O42_01410	COG4191	Histidine kinase
G4O42_01415	COG0784	Response regulator, receiver
G4O42_01420	COG3173	Aminoglycoside phosphotransferase
G4O42_01435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4O42_01440	COG0778	Nitroreductase
G4O42_01445	COG0346	lactoylglutathione lyase activity
G4O42_01450	COG2259	Doxx family
G4O42_01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_01470	COG3773	Cell wall hydrolase
G4O42_01475	COG3540	Alkaline phosphatase
G4O42_01480	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4O42_01485	COG0805	protein transport
G4O42_01495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4O42_01500	COG0477	Major facilitator Superfamily
G4O42_01505	COG1309	transcriptional regulator
G4O42_01510	COG0252	asparaginase activity
G4O42_01515	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G4O42_01520	COG1405	negative regulation of cell septum assembly
G4O42_01520	COG3012	SEC-C Motif Domain Protein
G4O42_01535	COG1595	DNA-templated transcription, initiation
G4O42_01540	COG1595	DNA-templated transcription, initiation
G4O42_01545	COG1876	peptidase activity
G4O42_01550	COG0457	Tetratricopeptide repeat
G4O42_01555	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_01560	COG0366	Alpha amylase catalytic
G4O42_01565	COG0803	Belongs to the bacterial solute-binding protein 9 family
G4O42_01570	COG1121	(ABC) transporter
G4O42_01575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G4O42_01580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_01585	COG2310	stress, protein
G4O42_01590	COG2310	stress, protein
G4O42_01595	COG2310	stress, protein
G4O42_01600	COG0861	Integral membrane protein TerC family
G4O42_01610	COG3853	Toxic anion resistance protein (TelA)
G4O42_01615	COG0477	Major facilitator Superfamily
G4O42_01620	COG0517	IMP dehydrogenase activity
G4O42_01620	COG4175	Glycine betaine
G4O42_01625	COG4176	ABC-type proline glycine betaine transport system permease component
G4O42_01630	COG2113	Glycine betaine
G4O42_01635	COG1473	amidohydrolase
G4O42_01640	COG1288	antiporter activity
G4O42_01660	COG2814	Major facilitator Superfamily
G4O42_01665	COG1846	Transcriptional regulator
G4O42_01670	COG1280	lysine exporter protein (LysE YggA)
G4O42_01675	COG3403	YqcI/YcgG family
G4O42_01680	COG1113	amino acid transport
G4O42_01685	COG3665	Urea carboxylase-associated protein
G4O42_01700	COG1660	Displays ATPase and GTPase activities
G4O42_01705	COG1082	Xylose isomerase domain protein TIM barrel
G4O42_01710	COG2271	Major facilitator Superfamily
G4O42_01715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G4O42_01720	COG3458	cephalosporin-C deacetylase activity
G4O42_01725	COG3541	Predicted nucleotidyltransferase
G4O42_01730	COG0506	proline dehydrogenase activity
G4O42_01735	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_01740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_01745	COG2508	Transcriptional regulator
G4O42_01755	COG1587	Uroporphyrinogen-III synthase
G4O42_01755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4O42_01760	COG2146	nitrite reductase [NAD(P)H] activity
G4O42_01765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4O42_01770	COG0243	molybdopterin cofactor binding
G4O42_01775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G4O42_01780	COG2223	nitrite transmembrane transporter activity
G4O42_01785	COG0523	cobalamin synthesis protein
G4O42_01790	COG1063	alcohol dehydrogenase
G4O42_01795	COG1714	RDD family
G4O42_01805	COG2723	6-phospho-beta-galactosidase activity
G4O42_01820	COG3209	COG3209 Rhs family protein
G4O42_01825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G4O42_01830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
G4O42_01835	COG1733	regulation of RNA biosynthetic process
G4O42_01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_01850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_01855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G4O42_01870	COG2364	Membrane
G4O42_01875	COG1126	abc transporter atp-binding protein
G4O42_01880	COG0765	amino acid transport
G4O42_01890	COG0583	DNA-binding transcription factor activity
G4O42_01895	COG0163	prenyltransferase activity
G4O42_01900	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G4O42_01915	COG3104	oligopeptide transport
G4O42_01920	COG5434	Belongs to the glycosyl hydrolase 28 family
G4O42_01930	COG0697	spore germination
G4O42_01940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4O42_01945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_01950	COG0456	acetyltransferase
G4O42_01955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_01960	COG0765	amino acid transport
G4O42_01965	COG1126	abc transporter atp-binding protein
G4O42_01970	COG1473	amidohydrolase
G4O42_01975	COG2079	MmgE PrpD family protein
G4O42_01980	COG1136	(ABC) transporter
G4O42_01985	COG0577	efflux transmembrane transporter activity
G4O42_01990	COG0745	RESPONSE REGULATOR receiver
G4O42_01995	COG5002	protein histidine kinase activity
G4O42_01995	COG3850	Histidine kinase
G4O42_02000	COG0457	Tetratricopeptide repeat
G4O42_02015	COG0527	aspartate kinase activity
G4O42_02020	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_02025	COG4605	iron ion homeostasis
G4O42_02030	COG4604	ABC transporter, ATP-binding protein
G4O42_02035	COG4607	ABC-type enterochelin transport system periplasmic component
G4O42_02040	COG2814	Major facilitator Superfamily
G4O42_02045	COG1309	transcriptional regulator
G4O42_02050	COG0778	Nitroreductase
G4O42_02055	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G4O42_02060	COG0640	Transcriptional regulator
G4O42_02065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_02070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G4O42_02075	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_02080	COG4975	Glucose uptake
G4O42_02085	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_02090	COG4549	nuclear export factor GLE1
G4O42_02095	COG2372	response to copper ion
G4O42_02095	COG1276	copper resistance
G4O42_02100	COG1349	DNA-binding transcription factor activity
G4O42_02110	COG2213	PTS system mannitol-specific
G4O42_02115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_02125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G4O42_02135	COG0561	phosphatase activity
G4O42_02145	COG1914	H( )-stimulated, divalent metal cation uptake system
G4O42_02155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G4O42_02160	COG1984	allophanate hydrolase subunit 2
G4O42_02165	COG1414	Transcriptional regulator
G4O42_02170	COG2755	lipolytic protein G-D-S-L family
G4O42_02180	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_02185	COG0768	penicillin binding
G4O42_02190	COG4989	oxidoreductase activity
G4O42_02195	COG3711	transcriptional antiterminator
G4O42_02200	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_02205	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_02210	COG1917	Cupin 2, conserved barrel domain protein
G4O42_02215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_02220	COG3871	stress protein (general stress protein 26)
G4O42_02230	COG2814	Major facilitator Superfamily
G4O42_02235	COG1522	sequence-specific DNA binding
G4O42_02240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4O42_02240	COG0551	DNA topoisomerase type I activity
G4O42_02245	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
G4O42_02250	COG3706	GGDEF domain
G4O42_02255	COG5298	Protein conserved in bacteria
G4O42_02260	COG1215	transferase activity, transferring glycosyl groups
G4O42_02270	COG0531	amino acid
G4O42_02280	COG0028	Belongs to the TPP enzyme family
G4O42_02305	COG0457	Tetratricopeptide repeat
G4O42_02330	COG1914	H( )-stimulated, divalent metal cation uptake system
G4O42_02340	COG4876	unkown
G4O42_02350	COG2076	Multidrug Resistance protein
G4O42_02355	COG2217	Heavy metal translocating P-type atpase
G4O42_02360	COG3729	General stress protein
G4O42_02365	COG0662	Cupin 2, conserved barrel domain protein
G4O42_02370	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_02375	COG3546	catalase activity
G4O42_02380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G4O42_02385	COG3290	protein histidine kinase activity
G4O42_02390	COG4565	transcriptional regulatory protein
G4O42_02395	COG1301	dicarboxylic acid transport
G4O42_02400	COG0628	permease
G4O42_02405	COG1131	(ABC) transporter
G4O42_02410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4O42_02420	COG1960	acyl-CoA dehydrogenase activity
G4O42_02435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4O42_02440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_02450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G4O42_02455	COG0513	Belongs to the DEAD box helicase family
G4O42_02460	COG3402	PFAM membrane-flanked domain
G4O42_02465	COG3428	Bacterial PH domain
G4O42_02470	COG0705	Rhomboid family
G4O42_02480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G4O42_02485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4O42_02490	COG0864	Transcriptional regulator
G4O42_02495	COG2337	Toxic component of a toxin-antitoxin (TA) module
G4O42_02500	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_02505	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_02510	COG2172	sigma factor antagonist activity
G4O42_02515	COG2208	phosphoserine phosphatase activity
G4O42_02520	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_02530	COG1191	sigma factor activity
G4O42_02535	COG2208	phosphoserine phosphatase activity
G4O42_02540	COG2183	response to ionizing radiation
G4O42_02605	COG5444	nuclease activity
G4O42_02610	COG0457	Tetratricopeptide repeat
G4O42_02625	COG0477	Major facilitator Superfamily
G4O42_02630	COG1846	Transcriptional regulator
G4O42_02640	COG2030	dehydratase
G4O42_02655	COG1959	2 iron, 2 sulfur cluster binding
G4O42_02660	COG2910	NAD(P)H-binding
G4O42_02675	COG1278	Cold shock
G4O42_02680	COG1329	Transcriptional regulator
G4O42_02685	COG1937	Protein conserved in bacteria
G4O42_02690	COG2210	Belongs to the sulfur carrier protein TusA family
G4O42_02700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_02700	COG0425	Belongs to the sulfur carrier protein TusA family
G4O42_02705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_02705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_02710	COG0425	Belongs to the sulfur carrier protein TusA family
G4O42_02715	COG0730	response to heat
G4O42_02720	COG1794	racemase activity, acting on amino acids and derivatives
G4O42_02735	COG3621	Patatin-like phospholipase
G4O42_02745	COG0662	Cupin 2, conserved barrel domain protein
G4O42_02760	COG0277	FAD linked oxidase domain protein
G4O42_02785	COG0662	Cupin 2, conserved barrel domain protein
G4O42_02790	COG2318	DinB family
G4O42_02825	COG1064	alcohol dehydrogenase
G4O42_02830	COG0789	Transcriptional regulator
G4O42_02840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_02855	COG2814	Major facilitator Superfamily
G4O42_02860	COG1309	transcriptional regulator
G4O42_02865	COG0697	spore germination
G4O42_02870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_02875	COG5577	PFAM Coat F domain
G4O42_02885	COG1063	alcohol dehydrogenase
G4O42_02890	COG5577	PFAM Coat F domain
G4O42_02900	COG4585	Histidine kinase
G4O42_02905	COG2197	response regulator
G4O42_02910	COG2409	Drug exporters of the RND superfamily
G4O42_02915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G4O42_02925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_02930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_02940	COG2814	Major facilitator Superfamily
G4O42_02945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4O42_02955	COG0730	response to heat
G4O42_02960	COG0456	acetyltransferase
G4O42_02965	COG0789	Transcriptional regulator
G4O42_02965	COG4978	Transcriptional regulator
G4O42_02970	COG0697	spore germination
G4O42_02975	COG1051	belongs to the nudix hydrolase family
G4O42_02980	COG2226	methyltransferase
G4O42_02985	COG0473	3-isopropylmalate dehydrogenase activity
G4O42_02990	COG1802	Transcriptional regulator
G4O42_02995	COG1819	glycosyl
G4O42_03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_03015	COG1388	LysM domain
G4O42_03020	COG2814	Major facilitator Superfamily
G4O42_03025	COG2188	Transcriptional regulator
G4O42_03030	COG2186	Transcriptional regulator
G4O42_03035	COG2807	transmembrane transport
G4O42_03040	COG2076	Multidrug Resistance protein
G4O42_03045	COG2076	Multidrug Resistance protein
G4O42_03050	COG1309	transcriptional regulator
G4O42_03055	COG0531	amino acid
G4O42_03065	COG3832	glyoxalase III activity
G4O42_03070	COG0604	alcohol dehydrogenase
G4O42_03075	COG2814	Major facilitator Superfamily
G4O42_03115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G4O42_03120	COG0802	atpase or kinase
G4O42_03125	COG1214	PFAM Peptidase M22, glycoprotease
G4O42_03130	COG0456	acetyltransferase
G4O42_03135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G4O42_03140	COG0488	(ABC) transporter
G4O42_03155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G4O42_03160	COG0805	protein transport
G4O42_03170	COG1266	CAAX protease self-immunity
G4O42_03210	COG0457	Tetratricopeptide repeat
G4O42_03215	COG1063	alcohol dehydrogenase
G4O42_03220	COG2211	Major facilitator Superfamily
G4O42_03225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4O42_03235	COG1842	Phage shock protein A
G4O42_03240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4O42_03245	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G4O42_03250	COG4260	virion core protein, lumpy skin disease virus
G4O42_03255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G4O42_03255	COG2755	lipolytic protein G-D-S-L family
G4O42_03265	COG1595	DNA-templated transcription, initiation
G4O42_03270	COG1063	alcohol dehydrogenase
G4O42_03275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G4O42_03280	COG0823	Involved in the tonB-independent uptake of proteins
G4O42_03290	COG2132	Multicopper oxidase
G4O42_03295	COG1113	amino acid transport
G4O42_03300	COG0714	Associated with various cellular activities
G4O42_03305	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
G4O42_03310	COG1305	Transglutaminase-like
G4O42_03335	COG2252	PERMEase
G4O42_03340	COG3064	Membrane
G4O42_03360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G4O42_03365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G4O42_03370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G4O42_03375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G4O42_03380	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G4O42_03395	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G4O42_03405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G4O42_03410	COG0138	bifunctional purine biosynthesis protein purh
G4O42_03415	COG0151	Belongs to the GarS family
G4O42_03425	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G4O42_03430	COG1470	cell adhesion involved in biofilm formation
G4O42_03435	COG4496	protein, YerC YecD
G4O42_03440	COG0069	glutamate synthase activity
G4O42_03450	COG0210	DNA helicase
G4O42_03460	COG4851	CamS sex pheromone cAM373 precursor
G4O42_03465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4O42_03470	COG1285	pathogenesis
G4O42_03475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_03495	COG1309	transcriptional regulator
G4O42_03500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G4O42_03505	COG1597	lipid kinase activity
G4O42_03510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4O42_03520	COG1131	(ABC) transporter
G4O42_03560	COG5444	nuclease activity
G4O42_03590	COG3546	catalase activity
G4O42_03595	COG0454	-acetyltransferase
G4O42_03605	COG2323	membrane
G4O42_03610	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_03615	COG0346	lactoylglutathione lyase activity
G4O42_03620	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_03625	COG5583	Uncharacterized small protein (DUF2292)
G4O42_03630	COG0196	riboflavin kinase activity
G4O42_03635	COG0670	Belongs to the BI1 family
G4O42_03640	COG1846	Transcriptional regulator
G4O42_03645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4O42_03655	COG2124	cytochrome p450
G4O42_03655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4O42_03660	COG1368	sulfuric ester hydrolase activity
G4O42_03665	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G4O42_03670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_03675	COG1442	glycosyl transferase family 8
G4O42_03680	COG1216	Glycosyl transferase, family 2
G4O42_03685	COG1442	glycosyl transferase family 8
G4O42_03690	COG2223	nitrite transmembrane transporter activity
G4O42_03695	COG0531	amino acid
G4O42_03700	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_03705	COG0840	transmembrane signaling receptor activity
G4O42_03710	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_03715	COG0457	Tetratricopeptide repeat
G4O42_03715	COG0463	Glycosyl transferase, family 2
G4O42_03720	COG0488	(ABC) transporter
G4O42_03725	COG0789	Transcriptional regulator
G4O42_03730	COG2814	Major facilitator Superfamily
G4O42_03735	COG0488	(ABC) transporter
G4O42_03740	COG0513	Belongs to the DEAD box helicase family
G4O42_03745	COG0456	acetyltransferase
G4O42_03750	COG2130	NADP-dependent
G4O42_03765	COG3866	Pectate lyase
G4O42_03770	COG0471	metal ion transport
G4O42_03790	COG3290	protein histidine kinase activity
G4O42_03795	COG4565	transcriptional regulatory protein
G4O42_03800	COG3181	Tripartite tricarboxylate transporter family receptor
G4O42_03805	COG2851	Citrate transporter
G4O42_03810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_03815	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
G4O42_03825	COG2258	MOSC domain
G4O42_03845	COG0024	Methionine aminopeptidase
G4O42_03850	COG1263	PTS System
G4O42_03850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_03860	COG1368	sulfuric ester hydrolase activity
G4O42_03870	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_03885	COG1263	PTS System
G4O42_03885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_03890	COG0366	Alpha amylase catalytic
G4O42_03895	COG2188	Transcriptional regulator
G4O42_03900	COG0778	Nitroreductase
G4O42_03915	COG0737	Belongs to the 5'-nucleotidase family
G4O42_03920	COG0693	protein deglycase activity
G4O42_03925	COG1609	Transcriptional regulator
G4O42_03940	COG2814	Major facilitator Superfamily
G4O42_03950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4O42_03955	COG4980	gas vesicle protein
G4O42_03960	COG1295	ribonuclease BN
G4O42_03965	COG0477	Major facilitator Superfamily
G4O42_03970	COG0387	Pfam Sodium calcium exchanger
G4O42_03980	COG0668	transmembrane transport
G4O42_03985	COG0535	radical SAM domain protein
G4O42_03995	COG0726	polysaccharide deacetylase
G4O42_04015	COG0745	RESPONSE REGULATOR receiver
G4O42_04020	COG2205	protein histidine kinase activity
G4O42_04025	COG2084	Dehydrogenase
G4O42_04035	COG0598	Magnesium transport protein CorA
G4O42_04040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
G4O42_04045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G4O42_04055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G4O42_04060	COG4637	Psort location Cytoplasmic, score
G4O42_04065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4O42_04070	COG0022	dehydrogenase e1 component
G4O42_04075	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_04080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4O42_04085	COG3284	Transcriptional regulator
G4O42_04095	COG1486	melibiose metabolic process
G4O42_04100	COG1737	Transcriptional regulator
G4O42_04105	COG1263	PTS System
G4O42_04105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_04115	COG1132	(ABC) transporter
G4O42_04120	COG1132	(ABC) transporter
G4O42_04125	COG2259	Doxx family
G4O42_04130	COG2514	catechol 2,3-dioxygenase activity
G4O42_04140	COG1695	Transcriptional regulator
G4O42_04145	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4O42_04150	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
G4O42_04155	COG3848	Pyruvate phosphate dikinase
G4O42_04155	COG0574	Belongs to the PEP-utilizing enzyme family
G4O42_04160	COG2732	(Barnase) inhibitor
G4O42_04165	COG2318	DinB family
G4O42_04170	COG2814	Major facilitator Superfamily
G4O42_04175	COG1846	Transcriptional regulator
G4O42_04180	COG0392	lysyltransferase activity
G4O42_04180	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
G4O42_04185	COG0384	phenazine biosynthesis protein PhzF
G4O42_04190	COG0778	Nitroreductase
G4O42_04205	COG1090	epimerase
G4O42_04220	COG2814	Major facilitator Superfamily
G4O42_04230	COG3591	Belongs to the peptidase S1B family
G4O42_04245	COG3103	Sh3 type 3 domain protein
G4O42_04250	COG5658	integral membrane protein
G4O42_04255	COG0596	Alpha beta hydrolase
G4O42_04260	COG0463	Glycosyl transferase, family 2
G4O42_04265	COG4485	Bacterial membrane protein, YfhO
G4O42_04270	COG1988	membrane-bound metal-dependent
G4O42_04275	COG1194	a g-specific adenine glycosylase
G4O42_04285	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_04305	COG1132	(ABC) transporter
G4O42_04310	COG4129	membrane
G4O42_04320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G4O42_04325	COG0735	belongs to the Fur family
G4O42_04440	COG3340	Belongs to the peptidase S51 family
G4O42_04450	COG0277	FAD linked oxidase domain protein
G4O42_04460	COG0747	negative chemotaxis
G4O42_04465	COG0601	transmembrane transport
G4O42_04470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_04475	COG0444	Belongs to the ABC transporter superfamily
G4O42_04480	COG4608	Belongs to the ABC transporter superfamily
G4O42_04485	COG0753	catalase activity
G4O42_04495	COG1116	anion transmembrane transporter activity
G4O42_04500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4O42_04505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4O42_04525	COG1476	TRANSCRIPTIONal
G4O42_04535	COG3382	B3 4 domain protein
G4O42_04540	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G4O42_04550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G4O42_04555	COG0789	Transcriptional regulator
G4O42_04560	COG1664	Polymer-forming cytoskeletal
G4O42_04565	COG1664	Polymer-forming cytoskeletal
G4O42_04570	COG2766	serine protein kinase
G4O42_04580	COG1846	Transcriptional regulator
G4O42_04585	COG1566	PFAM secretion protein HlyD family protein
G4O42_04590	COG2814	Major facilitator Superfamily
G4O42_04595	COG0655	NAD(P)H dehydrogenase (quinone) activity
G4O42_04610	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4O42_04615	COG1278	Cold shock
G4O42_04620	COG1464	Belongs to the NlpA lipoprotein family
G4O42_04625	COG3706	GGDEF domain
G4O42_04630	COG1823	symporter activity
G4O42_04650	COG5577	PFAM Coat F domain
G4O42_04655	COG1525	nuclease
G4O42_04655	COG0737	Belongs to the 5'-nucleotidase family
G4O42_04655	COG4085	toxin activity
G4O42_04660	COG3764	Sortase (surface protein transpeptidase)
G4O42_04665	COG0564	pseudouridine synthase activity
G4O42_04675	COG0517	IMP dehydrogenase activity
G4O42_04680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4O42_04685	COG3153	acetyltransferase
G4O42_04685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4O42_04690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4O42_04695	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
G4O42_04700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G4O42_04710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G4O42_04715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G4O42_04720	COG4585	Histidine kinase
G4O42_04720	COG2203	Gaf domain
G4O42_04725	COG2197	response regulator
G4O42_04730	COG0431	NADPH-dependent FMN reductase
G4O42_04745	COG0791	NLP P60 protein
G4O42_04745	COG1388	LysM domain
G4O42_04750	COG1959	2 iron, 2 sulfur cluster binding
G4O42_04755	COG0668	transmembrane transport
G4O42_04760	COG2719	SpoVR family
G4O42_04765	COG1785	Belongs to the alkaline phosphatase family
G4O42_04770	COG0791	NLP P60 protein
G4O42_04770	COG1388	LysM domain
G4O42_04775	COG0583	DNA-binding transcription factor activity
G4O42_04780	COG0372	Belongs to the citrate synthase family
G4O42_04785	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_04790	COG0531	amino acid
G4O42_04795	COG0733	neurotransmitter:sodium symporter activity
G4O42_04810	COG1595	DNA-templated transcription, initiation
G4O42_04815	COG0204	Acyl-transferase
G4O42_04820	COG1253	flavin adenine dinucleotide binding
G4O42_04825	COG0789	Transcriptional regulator
G4O42_04830	COG0436	Aminotransferase
G4O42_04835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4O42_04840	COG1253	flavin adenine dinucleotide binding
G4O42_04845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4O42_04850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G4O42_04855	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_04865	COG0668	transmembrane transport
G4O42_04870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G4O42_04875	COG0726	polysaccharide deacetylase
G4O42_04880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_04885	COG3226	Transcriptional regulator
G4O42_04895	COG0589	response to stress
G4O42_04900	COG1132	(ABC) transporter
G4O42_04905	COG1132	(ABC) transporter
G4O42_04910	COG0702	epimerase
G4O42_04925	COG0189	ligase activity
G4O42_04930	COG0189	ligase activity
G4O42_04945	COG4335	DNA alkylation repair
G4O42_04950	COG0561	phosphatase activity
G4O42_04955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4O42_04965	COG0475	glutathione-regulated potassium exporter activity
G4O42_04970	COG0490	domain, Protein
G4O42_04980	COG1024	Enoyl-CoA hydratase
G4O42_04990	COG4152	abc transporter atp-binding protein
G4O42_04995	COG1668	transmembrane transport
G4O42_05000	COG0420	3'-5' exonuclease activity
G4O42_05005	COG4717	serine-type aminopeptidase activity
G4O42_05020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G4O42_05055	COG4980	gas vesicle protein
G4O42_05070	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G4O42_05075	COG0537	adenosine 5'-monophosphoramidase activity
G4O42_05080	COG1131	(ABC) transporter
G4O42_05085	COG4473	ABC transporter
G4O42_05095	COG1473	amidohydrolase
G4O42_05100	COG3069	C4-dicarboxylate transmembrane transporter activity
G4O42_05105	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_05110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_05130	COG1309	transcriptional regulator
G4O42_05135	COG1511	domain protein
G4O42_05140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4O42_05150	COG1363	Peptidase, m42
G4O42_05155	COG1301	dicarboxylic acid transport
G4O42_05165	COG1234	tRNA 3'-trailer cleavage
G4O42_05170	COG0095	Lipoate-protein ligase
G4O42_05175	COG0702	epimerase
G4O42_05180	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_05190	COG0501	Belongs to the peptidase M48B family
G4O42_05195	COG1404	Belongs to the peptidase S8 family
G4O42_05205	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G4O42_05210	COG0406	alpha-ribazole phosphatase activity
G4O42_05215	COG0183	Belongs to the thiolase family
G4O42_05220	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_05225	COG1268	BioY protein
G4O42_05230	COG0840	transmembrane signaling receptor activity
G4O42_05235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4O42_05235	COG0723	plastoquinol--plastocyanin reductase activity
G4O42_05240	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_05250	COG4903	ComK protein
G4O42_05260	COG5646	InterPro IPR014922
G4O42_05280	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_05295	COG0398	Pfam SNARE associated Golgi protein
G4O42_05300	COG0681	Belongs to the peptidase S26 family
G4O42_05305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G4O42_05310	COG1846	Transcriptional regulator
G4O42_05315	COG3180	Ammonia monooxygenase
G4O42_05320	COG2814	Major facilitator Superfamily
G4O42_05330	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
G4O42_05335	COG2323	membrane
G4O42_05350	COG0420	3'-5' exonuclease activity
G4O42_05355	COG0419	ATPase involved in DNA repair
G4O42_05360	COG1403	HNH endonuclease
G4O42_05400	COG0179	Fumarylacetoacetate (FAA) hydrolase
G4O42_05415	COG0367	asparagine synthase
G4O42_05420	COG1562	ergosterol biosynthetic process
G4O42_05425	COG0534	Mate efflux family protein
G4O42_05430	COG1917	Cupin 2, conserved barrel domain protein
G4O42_05430	COG2207	Transcriptional regulator
G4O42_05440	COG2318	DinB family
G4O42_05445	COG1279	arginine transmembrane transporter activity
G4O42_05450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_05455	COG1357	PFAM Pentapeptide repeats (8 copies)
G4O42_05460	COG2153	protein acetylation
G4O42_05465	COG0646	methionine synthase
G4O42_05465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G4O42_05475	COG2996	Protein conserved in bacteria
G4O42_05485	COG0840	transmembrane signaling receptor activity
G4O42_05490	COG2124	cytochrome p450
G4O42_05500	COG1307	EDD domain protein, DegV family
G4O42_05505	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_05520	COG0561	phosphatase activity
G4O42_05525	COG1073	alpha beta
G4O42_05530	COG2151	metal-sulfur cluster biosynthetic enzyme
G4O42_05540	COG0277	FAD linked oxidase domain protein
G4O42_05545	COG2271	Major facilitator Superfamily
G4O42_05555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G4O42_05565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4O42_05570	COG0505	Belongs to the CarA family
G4O42_05575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4O42_05580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G4O42_05595	COG2267	carboxylic ester hydrolase activity
G4O42_05605	COG1744	ABC transporter substrate-binding protein PnrA-like
G4O42_05620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4O42_05625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G4O42_05630	COG5504	Zn-dependent protease
G4O42_05635	COG0444	Belongs to the ABC transporter superfamily
G4O42_05640	COG4608	Belongs to the ABC transporter superfamily
G4O42_05650	COG0601	transmembrane transport
G4O42_05655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_05665	COG0180	Tryptophanyl-tRNA synthetase
G4O42_05670	COG4166	transmembrane transport
G4O42_05675	COG0601	transmembrane transport
G4O42_05680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_05685	COG0444	Belongs to the ABC transporter superfamily
G4O42_05690	COG4608	Belongs to the ABC transporter superfamily
G4O42_05700	COG0456	acetyltransferase
G4O42_05705	COG1393	Belongs to the ArsC family
G4O42_05710	COG0861	Integral membrane protein TerC family
G4O42_05715	COG4862	establishment of competence for transformation
G4O42_05720	COG4469	Competence protein
G4O42_05725	COG1164	Oligoendopeptidase f
G4O42_05735	COG2346	COG2346, Truncated hemoglobins
G4O42_05740	COG0741	lytic transglycosylase activity
G4O42_05745	COG4116	CYTH
G4O42_05755	COG2357	RelA SpoT domain protein
G4O42_05760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4O42_05765	COG0564	pseudouridine synthase activity
G4O42_05775	COG0569	domain protein
G4O42_05775	COG0475	glutathione-regulated potassium exporter activity
G4O42_05780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G4O42_05785	COG0352	thiamine-phosphate diphosphorylase activity
G4O42_05790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4O42_05795	COG2104	thiamine diphosphate biosynthetic process
G4O42_05805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4O42_05810	COG0351	phosphomethylpyrimidine kinase
G4O42_05815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G4O42_05870	COG0210	DNA helicase
G4O42_05890	COG1131	(ABC) transporter
G4O42_05900	COG2153	protein acetylation
G4O42_05910	COG2382	esterase
G4O42_05915	COG0626	cystathionine gamma-synthase activity
G4O42_05920	COG0626	cystathionine gamma-synthase activity
G4O42_05950	COG5444	nuclease activity
G4O42_05960	COG0346	lactoylglutathione lyase activity
G4O42_05965	COG2367	Beta-lactamase
G4O42_05970	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G4O42_05975	COG0477	Major facilitator Superfamily
G4O42_05980	COG1846	Transcriptional regulator
G4O42_05990	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G4O42_05995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4O42_06000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G4O42_06005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_06005	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_06010	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4O42_06020	COG1349	DNA-binding transcription factor activity
G4O42_06040	COG1285	pathogenesis
G4O42_06055	COG2205	protein histidine kinase activity
G4O42_06065	COG3383	formate dehydrogenase (NAD+) activity
G4O42_06070	COG2427	Protein of unknown function (DUF1641)
G4O42_06075	COG2124	cytochrome p450
G4O42_06080	COG1819	glycosyl
G4O42_06090	COG1587	Uroporphyrinogen-III synthase
G4O42_06095	COG0390	transport system, permease component
G4O42_06100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4O42_06105	COG0697	spore germination
G4O42_06110	COG4297	protein containing double-stranded beta helix domain
G4O42_06120	COG1252	NADH dehydrogenase
G4O42_06130	COG2211	Major facilitator Superfamily
G4O42_06135	COG1609	Transcriptional regulator
G4O42_06140	COG0246	Mannitol dehydrogenase
G4O42_06145	COG2721	sulfolactate sulfo-lyase activity
G4O42_06150	COG0745	RESPONSE REGULATOR receiver
G4O42_06155	COG2205	protein histidine kinase activity
G4O42_06155	COG2770	Histidine kinase
G4O42_06175	COG4585	Histidine kinase
G4O42_06180	COG2197	response regulator
G4O42_06205	COG0730	response to heat
G4O42_06210	COG2318	DinB family
G4O42_06215	COG0457	Tetratricopeptide repeat
G4O42_06225	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4O42_06225	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_06225	COG1388	LysM domain
G4O42_06235	COG4195	phage-related replication protein
G4O42_06240	COG2856	Zn peptidase
G4O42_06245	COG1396	sequence-specific DNA binding
G4O42_06255	COG1522	sequence-specific DNA binding
G4O42_06260	COG1484	DNA-dependent DNA replication
G4O42_06275	COG1595	DNA-templated transcription, initiation
G4O42_06280	COG5484	DNA packaging
G4O42_06280	COG3728	DNA packaging
G4O42_06285	COG1783	phage Terminase large subunit
G4O42_06290	COG5518	Phage portal protein
G4O42_06295	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G4O42_06300	COG4653	Phage capsid family
G4O42_06350	COG3953	SLT domain
G4O42_06350	COG5412	phage tail tape measure protein
G4O42_06350	COG3953	SLT domain
G4O42_06350	COG5412	phage tail tape measure protein
G4O42_06350	COG5412	phage tail tape measure protein
G4O42_06350	COG3953	SLT domain
G4O42_06355	COG1652	LysM domain
G4O42_06360	COG4193	domain, Protein
G4O42_06370	COG3628	GPW Gp25 family protein
G4O42_06375	COG3299	homolog of phage Mu protein gp47
G4O42_06380	COG3778	Protein conserved in bacteria
G4O42_06420	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_06420	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4O42_06435	COG0306	phosphate transporter
G4O42_06440	COG1392	Phosphate transport regulator
G4O42_06445	COG0531	amino acid
G4O42_06450	COG0346	lactoylglutathione lyase activity
G4O42_06455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G4O42_06460	COG0463	Glycosyl transferase, family 2
G4O42_06465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_06470	COG0477	Major facilitator Superfamily
G4O42_06475	COG2362	D-Aminopeptidase
G4O42_06480	COG0601	transmembrane transport
G4O42_06485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G4O42_06490	COG0444	Belongs to the ABC transporter superfamily
G4O42_06495	COG4166	transmembrane transport
G4O42_06500	COG1619	proteins homologs of microcin C7 resistance protein MccF
G4O42_06505	COG4948	Mandelate Racemase Muconate Lactonizing
G4O42_06510	COG0791	NLP P60 protein
G4O42_06515	COG4608	Belongs to the ABC transporter superfamily
G4O42_06520	COG2706	6-phosphogluconolactonase activity
G4O42_06525	COG1834	amidinotransferase
G4O42_06530	COG1607	acyl-coa hydrolase
G4O42_06535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_06540	COG2076	Multidrug Resistance protein
G4O42_06545	COG2076	Multidrug Resistance protein
G4O42_06550	COG0788	formyltetrahydrofolate deformylase activity
G4O42_06555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G4O42_06565	COG1764	response to oxidative stress
G4O42_06570	COG1846	Transcriptional regulator
G4O42_06575	COG1764	response to oxidative stress
G4O42_06590	COG0457	Tetratricopeptide repeat
G4O42_06590	COG0463	Glycosyl transferase, family 2
G4O42_06610	COG1404	Belongs to the peptidase S8 family
G4O42_06615	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_06620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G4O42_06625	COG1122	ATPase activity
G4O42_06630	COG4721	ABC-type cobalt transport system, permease component
G4O42_06635	COG3858	chitin binding
G4O42_06635	COG1388	LysM domain
G4O42_06650	COG2239	Acts as a magnesium transporter
G4O42_06655	COG0789	Transcriptional regulator
G4O42_06670	COG1846	Transcriptional regulator
G4O42_06675	COG0726	polysaccharide deacetylase
G4O42_06680	COG1793	dna ligase
G4O42_06680	COG3285	dna ligase
G4O42_06685	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G4O42_06690	COG0586	Pfam SNARE associated Golgi protein
G4O42_06695	COG0861	Integral membrane protein TerC family
G4O42_06700	COG1191	sigma factor activity
G4O42_06725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G4O42_06730	COG2323	membrane
G4O42_06740	COG3594	Acyltransferase
G4O42_06745	COG5002	protein histidine kinase activity
G4O42_06750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4O42_06765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G4O42_06770	COG0436	Aminotransferase
G4O42_06800	COG3852	Histidine kinase
G4O42_06805	COG1846	Transcriptional regulator
G4O42_06810	COG1360	Flagellar Motor Protein
G4O42_06815	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4O42_06820	COG0542	response to heat
G4O42_06825	COG3949	Membrane
G4O42_06840	COG0720	synthase
G4O42_06845	COG0602	queuosine metabolic process
G4O42_06860	COG1733	regulation of RNA biosynthetic process
G4O42_06865	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_06880	COG4873	Protein conserved in bacteria
G4O42_06890	COG3773	Cell wall hydrolase
G4O42_06895	COG2244	polysaccharide biosynthetic process
G4O42_06900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_06905	COG2217	Heavy metal translocating P-type atpase
G4O42_06910	COG0006	proline dipeptidase activity
G4O42_06915	COG1609	Transcriptional regulator
G4O42_06920	COG3711	transcriptional antiterminator
G4O42_06925	COG2190	(PTS) system
G4O42_06925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_06925	COG1263	PTS System
G4O42_06930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_06935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G4O42_06945	COG1533	DNA photolyase activity
G4O42_06950	COG0840	transmembrane signaling receptor activity
G4O42_06955	COG2084	Dehydrogenase
G4O42_06960	COG2340	Cysteine-rich secretory protein family
G4O42_06965	COG0768	penicillin binding
G4O42_06970	COG4191	Histidine kinase
G4O42_06975	COG0436	Aminotransferase
G4O42_06980	COG0835	chemotaxis
G4O42_06980	COG0784	Response regulator, receiver
G4O42_06990	COG2814	Major facilitator Superfamily
G4O42_06995	COG1376	ErfK ybiS ycfS ynhG family protein
G4O42_07000	COG1408	metallophosphoesterase
G4O42_07005	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_07015	COG2200	EAL domain
G4O42_07020	COG4703	Protein of unknown function (DUF1797)
G4O42_07025	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
G4O42_07035	COG0517	IMP dehydrogenase activity
G4O42_07040	COG0583	DNA-binding transcription factor activity
G4O42_07045	COG0716	FMN binding
G4O42_07055	COG0716	FMN binding
G4O42_07075	COG0668	transmembrane transport
G4O42_07080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_07100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4O42_07105	COG0303	'Molybdopterin
G4O42_07110	COG1763	Mo-molybdopterin cofactor biosynthetic process
G4O42_07115	COG0314	molybdopterin synthase activity
G4O42_07120	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G4O42_07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G4O42_07135	COG1136	(ABC) transporter
G4O42_07140	COG0577	efflux transmembrane transporter activity
G4O42_07145	COG1349	DNA-binding transcription factor activity
G4O42_07150	COG1105	Belongs to the carbohydrate kinase PfkB family
G4O42_07155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_07155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_07155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_07160	COG0681	Belongs to the peptidase S26 family
G4O42_07170	COG0488	(ABC) transporter
G4O42_07175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4O42_07180	COG2309	aminopeptidase activity
G4O42_07190	COG1077	Cell shape determining protein MreB Mrl
G4O42_07195	COG2002	toxin-antitoxin pair type II binding
G4O42_07200	COG3852	Histidine kinase
G4O42_07205	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
G4O42_07205	COG2105	PFAM AIG2 family protein
G4O42_07210	COG0569	domain protein
G4O42_07220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G4O42_07230	COG0561	phosphatase activity
G4O42_07235	COG0242	peptide deformylase activity
G4O42_07245	COG0497	DNA recombination
G4O42_07250	COG2070	2-Nitropropane dioxygenase
G4O42_07250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4O42_07255	COG4221	oxidoreductase activity
G4O42_07255	COG3321	synthase
G4O42_07255	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_07255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_07260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_07260	COG4221	oxidoreductase activity
G4O42_07260	COG0300	oxidoreductase activity
G4O42_07260	COG3321	synthase
G4O42_07265	COG3321	synthase
G4O42_07265	COG4221	oxidoreductase activity
G4O42_07265	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_07265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_07270	COG0300	oxidoreductase activity
G4O42_07270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_07270	COG3321	synthase
G4O42_07270	COG4221	oxidoreductase activity
G4O42_07275	COG0300	oxidoreductase activity
G4O42_07275	COG4221	oxidoreductase activity
G4O42_07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_07275	COG3321	synthase
G4O42_07280	COG0300	oxidoreductase activity
G4O42_07280	COG4221	oxidoreductase activity
G4O42_07280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_07280	COG3321	synthase
G4O42_07285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_07285	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_07285	COG3321	synthase
G4O42_07285	COG4221	oxidoreductase activity
G4O42_07290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_07295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4O42_07300	COG0022	dehydrogenase e1 component
G4O42_07305	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_07310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4O42_07315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_07330	COG1982	Orn Lys Arg decarboxylase major
G4O42_07350	COG0483	inositol monophosphate 1-phosphatase activity
G4O42_07360	COG3227	Zinc metalloprotease (Elastase)
G4O42_07395	COG4896	Protein conserved in bacteria
G4O42_07405	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G4O42_07410	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4O42_07415	COG2066	Belongs to the glutaminase family
G4O42_07425	COG0772	Belongs to the SEDS family
G4O42_07430	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G4O42_07445	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4O42_07445	COG2010	Cytochrome c
G4O42_07450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4O42_07455	COG1845	cytochrome c oxidase, subunit III
G4O42_07460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G4O42_07465	COG3336	cytochrome c oxidase
G4O42_07475	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G4O42_07480	COG2340	Cysteine-rich secretory protein family
G4O42_07495	COG3679	Belongs to the UPF0342 family
G4O42_07505	COG0742	ribosomal rna small subunit methyltransferase
G4O42_07515	COG3314	Sporulation integral membrane protein YlbJ
G4O42_07520	COG1752	Esterase of the alpha-beta hydrolase superfamily
G4O42_07525	COG3480	Lon protease (S16) C-terminal proteolytic domain
G4O42_07535	COG1399	metal-binding, possibly nucleic acid-binding protein
G4O42_07555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G4O42_07575	COG4839	cell division protein FtsL
G4O42_07585	COG0768	penicillin binding
G4O42_07605	COG0772	Belongs to the SEDS family
G4O42_07620	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G4O42_07625	COG0849	cell division
G4O42_07630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G4O42_07635	COG1404	Belongs to the peptidase S8 family
G4O42_07635	COG4412	M6 family metalloprotease domain protein
G4O42_07645	COG1191	sigma factor activity
G4O42_07650	COG1191	sigma factor activity
G4O42_07655	COG1119	ATPase activity
G4O42_07660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_07665	COG1873	PFAM PRC-barrel domain
G4O42_07675	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G4O42_07685	COG0762	integral membrane protein
G4O42_07690	COG2302	S4 RNA-binding domain
G4O42_07695	COG3599	regulation of cell shape
G4O42_07700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G4O42_07705	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4O42_07715	COG0564	pseudouridine synthase activity
G4O42_07725	COG2233	PERMEase
G4O42_07735	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G4O42_07740	COG0505	Belongs to the CarA family
G4O42_07745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G4O42_07760	COG0284	orotidine-5'-phosphate decarboxylase activity
G4O42_07765	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G4O42_07775	COG0306	phosphate transporter
G4O42_07790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G4O42_07795	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
G4O42_07800	COG1648	precorrin-2 dehydrogenase activity
G4O42_07810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G4O42_07815	COG1561	YicC-like family, N-terminal region
G4O42_07825	COG0194	GDP metabolic process
G4O42_07835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4O42_07840	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G4O42_07845	COG0242	peptide deformylase activity
G4O42_07855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G4O42_07855	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G4O42_07865	COG0631	protein serine/threonine phosphatase activity
G4O42_07870	COG2815	serine threonine protein kinase
G4O42_07870	COG0515	serine threonine protein kinase
G4O42_07880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G4O42_07885	COG1564	THIamine pyrophosphokinase
G4O42_07900	COG1302	Protein conserved in bacteria
G4O42_07905	COG1461	Dihydroxyacetone kinase
G4O42_07910	COG1760	l-serine dehydratase
G4O42_07915	COG1760	l-serine dehydratase
G4O42_07920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G4O42_07935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4O42_07940	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_07955	COG1196	nuclear chromosome segregation
G4O42_07960	COG0552	protein localization to endoplasmic reticulum
G4O42_07975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G4O42_07985	COG1837	Belongs to the UPF0109 family
G4O42_08010	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G4O42_08025	COG2257	FlhB HrpN YscU SpaS Family
G4O42_08035	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G4O42_08040	COG0758	DNA mediated transformation
G4O42_08045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G4O42_08055	COG4974	Belongs to the 'phage' integrase family
G4O42_08075	COG1815	bacterial-type flagellum-dependent cell motility
G4O42_08080	COG1558	bacterial-type flagellum-dependent cell motility
G4O42_08085	COG1677	Flagellar hook-basal body complex protein FliE
G4O42_08090	COG1766	The M ring may be actively involved in energy transduction
G4O42_08095	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4O42_08100	COG1317	bacterial-type flagellum organization
G4O42_08105	COG1157	protein secretion by the type III secretion system
G4O42_08110	COG2882	bacterial-type flagellum organization
G4O42_08115	COG3334	PFAM MgtE intracellular
G4O42_08120	COG3144	bacterial-type flagellum assembly
G4O42_08125	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G4O42_08130	COG4786	Flagellar basal body rod
G4O42_08135	COG1582	Flagellar protein (FlbD)
G4O42_08140	COG1580	Controls the rotational direction of flagella during chemotaxis
G4O42_08145	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4O42_08150	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G4O42_08150	COG1776	CheC inhibitor of MCP methylation
G4O42_08155	COG2201	protein-glutamate methylesterase activity
G4O42_08160	COG3190	flagellar
G4O42_08165	COG1338	Plays a role in the flagellum-specific transport system
G4O42_08170	COG1987	bacterial-type flagellum assembly
G4O42_08175	COG1684	flagellar biosynthetic protein fliR
G4O42_08180	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4O42_08185	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G4O42_08190	COG1419	protein localization to endoplasmic reticulum
G4O42_08195	COG0455	bacterial-type flagellum organization
G4O42_08200	COG2201	protein-glutamate methylesterase activity
G4O42_08205	COG0643	Histidine kinase
G4O42_08205	COG2198	Histidine kinase
G4O42_08210	COG0835	chemotaxis
G4O42_08215	COG1776	CheC inhibitor of MCP methylation
G4O42_08225	COG1191	sigma factor activity
G4O42_08255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G4O42_08260	COG4589	Belongs to the CDS family
G4O42_08270	COG0750	zinc metalloprotease
G4O42_08280	COG2176	DNA-directed DNA polymerase activity
G4O42_08290	COG0195	Participates in both transcription termination and antitermination
G4O42_08295	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G4O42_08300	COG1358	cellular component organization or biogenesis
G4O42_08310	COG1550	Protein conserved in bacteria
G4O42_08325	COG0196	riboflavin kinase activity
G4O42_08340	COG0726	polysaccharide deacetylase
G4O42_08345	COG0612	Peptidase, M16
G4O42_08350	COG1873	PFAM PRC-barrel domain
G4O42_08355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4O42_08360	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G4O42_08365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G4O42_08370	COG0527	aspartate kinase activity
G4O42_08380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G4O42_08385	COG0740	serine-type endopeptidase activity
G4O42_08395	COG4980	gas vesicle protein
G4O42_08395	COG1674	ftsk spoiiie
G4O42_08400	COG2188	Transcriptional regulator
G4O42_08405	COG2814	Major facilitator Superfamily
G4O42_08410	COG1846	Transcriptional regulator
G4O42_08415	COG1033	growth of symbiont in host cell
G4O42_08415	COG2409	Drug exporters of the RND superfamily
G4O42_08420	COG0612	Peptidase, M16
G4O42_08425	COG0612	Peptidase, M16
G4O42_08430	COG0300	oxidoreductase activity
G4O42_08445	COG1426	Protein conserved in bacteria
G4O42_08450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G4O42_08465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G4O42_08475	COG1692	metallophosphoesterase
G4O42_08480	COG2359	stage V sporulation protein S
G4O42_08500	COG4550	Control of competence regulator ComK, YlbF/YmcA
G4O42_08545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_08550	COG3425	synthase
G4O42_08555	COG1024	Enoyl-CoA hydratase
G4O42_08560	COG1024	Enoyl-CoA hydratase
G4O42_08565	COG3321	synthase
G4O42_08565	COG0300	oxidoreductase activity
G4O42_08565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_08565	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_08565	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_08570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_08570	COG3321	synthase
G4O42_08570	COG4221	oxidoreductase activity
G4O42_08570	COG0300	oxidoreductase activity
G4O42_08575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_08575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_08575	COG3321	synthase
G4O42_08575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_08575	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_08575	COG3321	synthase
G4O42_08575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_08575	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_08575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_08575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_08580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_08580	COG4221	oxidoreductase activity
G4O42_08580	COG3321	synthase
G4O42_08580	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_08585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_08585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G4O42_08585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G4O42_08585	COG3321	synthase
G4O42_08590	COG2124	cytochrome p450
G4O42_08595	COG3209	COG3209 Rhs family protein
G4O42_08600	COG3619	membrane
G4O42_08610	COG1404	Belongs to the peptidase S8 family
G4O42_08620	COG4195	phage-related replication protein
G4O42_08625	COG1764	response to oxidative stress
G4O42_08635	COG2076	Multidrug Resistance protein
G4O42_08675	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4O42_08680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G4O42_08685	COG4112	unkown
G4O42_08690	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_08700	COG0464	growth
G4O42_08705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G4O42_08710	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
G4O42_08715	COG0789	Transcriptional regulator
G4O42_08720	COG0174	glutamine synthetase
G4O42_08760	COG2211	Major facilitator Superfamily
G4O42_08765	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_08780	COG1070	Carbohydrate kinase
G4O42_08785	COG3848	Pyruvate phosphate dikinase
G4O42_08785	COG0574	Belongs to the PEP-utilizing enzyme family
G4O42_08810	COG1064	alcohol dehydrogenase
G4O42_08815	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G4O42_08815	COG4451	ribulose bisphosphate carboxylase, small
G4O42_08855	COG3397	chitin binding
G4O42_08875	COG5434	Belongs to the glycosyl hydrolase 28 family
G4O42_08880	COG0756	dUTP diphosphatase activity
G4O42_08885	COG4195	phage-related replication protein
G4O42_08915	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4O42_08925	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G4O42_08945	COG0785	Cytochrome C biogenesis protein
G4O42_08950	COG2201	protein-glutamate methylesterase activity
G4O42_08955	COG4846	Membrane protein involved in cytochrome C biogenesis
G4O42_08965	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_08980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G4O42_08985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_09005	COG0824	Thioesterase
G4O42_09015	COG4841	protein insertion into membrane
G4O42_09025	COG1832	CoA-binding protein
G4O42_09030	COG0187	DNA topoisomerase II activity
G4O42_09035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G4O42_09045	COG1115	amino acid carrier protein
G4O42_09055	COG1063	alcohol dehydrogenase
G4O42_09060	COG0800	Aldolase
G4O42_09065	COG1312	Catalyzes the dehydration of D-mannonate
G4O42_09070	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_09075	COG1609	Transcriptional regulator
G4O42_09080	COG2271	Major facilitator Superfamily
G4O42_09125	COG2205	protein histidine kinase activity
G4O42_09130	COG0745	RESPONSE REGULATOR receiver
G4O42_09140	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_09165	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_09170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4O42_09175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4O42_09180	COG2610	gluconate transmembrane transporter activity
G4O42_09185	COG2124	cytochrome p450
G4O42_09205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4O42_09215	COG2246	polysaccharide biosynthetic process
G4O42_09225	COG0586	Pfam SNARE associated Golgi protein
G4O42_09230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4O42_09235	COG1024	Enoyl-CoA hydratase
G4O42_09240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G4O42_09245	COG0511	ligase activity, forming carbon-carbon bonds
G4O42_09250	COG0439	Biotin carboxylase
G4O42_09255	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_09260	COG1960	acyl-CoA dehydrogenase activity
G4O42_09265	COG1649	PFAM Uncharacterised BCR, COG1649
G4O42_09275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_09275	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G4O42_09280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_09285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_09290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_09295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_09300	COG2027	D-alanyl-D-alanine carboxypeptidase
G4O42_09305	COG2017	converts alpha-aldose to the beta-anomer
G4O42_09310	COG0534	Mate efflux family protein
G4O42_09325	COG0582	viral genome integration into host DNA
G4O42_09330	COG0166	Belongs to the GPI family
G4O42_09335	COG0405	Gamma-glutamyltransferase
G4O42_09340	COG2814	Major facilitator Superfamily
G4O42_09345	COG0640	Transcriptional regulator
G4O42_09350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G4O42_09360	COG0604	alcohol dehydrogenase
G4O42_09365	COG0493	'glutamate synthase
G4O42_09370	COG0067	glutamate synthase
G4O42_09370	COG0069	glutamate synthase activity
G4O42_09370	COG0070	glutamate synthase
G4O42_09375	COG0583	DNA-binding transcription factor activity
G4O42_09380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G4O42_09395	COG0300	oxidoreductase activity
G4O42_09400	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
G4O42_09410	COG2814	Major facilitator Superfamily
G4O42_09415	COG1070	Carbohydrate kinase
G4O42_09420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4O42_09425	COG0243	molybdopterin cofactor binding
G4O42_09455	COG5444	nuclease activity
G4O42_09460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_09465	COG2207	Transcriptional regulator
G4O42_09465	COG0662	Cupin 2, conserved barrel domain protein
G4O42_09470	COG1309	transcriptional regulator
G4O42_09475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_09485	COG0640	Transcriptional regulator
G4O42_09490	COG0741	lytic transglycosylase activity
G4O42_09495	COG2322	membrane
G4O42_09510	COG1619	proteins homologs of microcin C7 resistance protein MccF
G4O42_09520	COG1388	LysM domain
G4O42_09520	COG3584	3D domain protein
G4O42_09525	COG0514	ATP-dependent DNA helicase (RecQ)
G4O42_09535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G4O42_09540	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4O42_09555	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_09585	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_09590	COG1657	PFAM Prenyltransferase squalene oxidase
G4O42_09595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G4O42_09600	COG0733	neurotransmitter:sodium symporter activity
G4O42_09605	COG0385	Bile acid
G4O42_09610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_09615	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_09625	COG4548	von Willebrand factor, type A
G4O42_09630	COG0714	Associated with various cellular activities
G4O42_09635	COG2032	superoxide dismutase activity
G4O42_09640	COG0791	NLP P60 protein
G4O42_09640	COG1388	LysM domain
G4O42_09645	COG1819	glycosyl
G4O42_09650	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G4O42_09655	COG0534	Mate efflux family protein
G4O42_09660	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_09665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_09670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_09680	COG2962	Rard protein
G4O42_09695	COG1942	4-Oxalocrotonate Tautomerase
G4O42_09705	COG1733	regulation of RNA biosynthetic process
G4O42_09710	COG0778	Nitroreductase
G4O42_09715	COG0400	carboxylic ester hydrolase activity
G4O42_09720	COG0346	lactoylglutathione lyase activity
G4O42_09730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G4O42_09740	COG2723	6-phospho-beta-galactosidase activity
G4O42_09745	COG2188	Transcriptional regulator
G4O42_09750	COG0793	Belongs to the peptidase S41A family
G4O42_09750	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_09755	COG2226	methyltransferase
G4O42_09765	COG1876	peptidase activity
G4O42_09785	COG0671	phosphoesterase, PA-phosphatase related
G4O42_09810	COG1509	lysine 2,3-aminomutase activity
G4O42_09815	COG0456	acetyltransferase
G4O42_09820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_09825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G4O42_09830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G4O42_09835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G4O42_09840	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
G4O42_09850	COG0456	acetyltransferase
G4O42_09855	COG0463	Glycosyl transferase, family 2
G4O42_09870	COG4641	Protein conserved in bacteria
G4O42_09880	COG1086	Polysaccharide biosynthesis protein
G4O42_09915	COG0457	Tetratricopeptide repeat
G4O42_09925	COG3391	amine dehydrogenase activity
G4O42_09945	COG5444	nuclease activity
G4O42_09950	COG4282	regulation of fungal-type cell wall biogenesis
G4O42_09955	COG1525	nuclease
G4O42_09960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4O42_09980	COG1846	Transcriptional regulator
G4O42_09985	COG4698	Protein conserved in bacteria
G4O42_09990	COG2755	lipolytic protein G-D-S-L family
G4O42_09995	COG1999	signal sequence binding
G4O42_10005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G4O42_10010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G4O42_10015	COG1272	protein, Hemolysin III
G4O42_10020	COG0204	Acyl-transferase
G4O42_10025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4O42_10040	COG2136	Putative SAM-dependent methyltransferase
G4O42_10040	COG2521	methyltransferase
G4O42_10055	COG1413	lyase activity
G4O42_10060	COG1418	mRNA catabolic process
G4O42_10065	COG0386	Belongs to the glutathione peroxidase family
G4O42_10075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G4O42_10085	COG1278	Cold shock
G4O42_10105	COG0328	RNA-DNA hybrid ribonuclease activity
G4O42_10110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G4O42_10115	COG0328	RNA-DNA hybrid ribonuclease activity
G4O42_10125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4O42_10140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G4O42_10150	COG1755	Isoprenylcysteine carboxyl methyltransferase
G4O42_10155	COG3424	synthase
G4O42_10175	COG1335	isochorismatase
G4O42_10185	COG2233	PERMEase
G4O42_10195	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G4O42_10200	COG1199	ATP-dependent helicase activity
G4O42_10215	COG0116	Belongs to the methyltransferase superfamily
G4O42_10245	COG3359	exonuclease
G4O42_10250	COG1205	dead DEAH box helicase
G4O42_10250	COG1111	helicase
G4O42_10255	COG2190	(PTS) system
G4O42_10260	COG0071	Belongs to the small heat shock protein (HSP20) family
G4O42_10300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_10300	COG4499	WXG100 protein secretion system (Wss), protein YukC
G4O42_10310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G4O42_10315	COG3935	DnaD domain protein
G4O42_10325	COG0436	Aminotransferase
G4O42_10330	COG5353	protein conserved in bacteria
G4O42_10340	COG1199	ATP-dependent helicase activity
G4O42_10340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G4O42_10370	COG0438	transferase activity, transferring glycosyl groups
G4O42_10375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_10390	COG1694	Mazg nucleotide pyrophosphohydrolase
G4O42_10395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_10410	COG4347	Protein of unknown function (DUF1405)
G4O42_10415	COG2010	Cytochrome c
G4O42_10415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G4O42_10420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G4O42_10425	COG0723	plastoquinol--plastocyanin reductase activity
G4O42_10440	COG0457	Tetratricopeptide repeat
G4O42_10450	COG0287	Prephenate dehydrogenase
G4O42_10485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G4O42_10490	COG4401	Chorismate mutase type I
G4O42_10505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G4O42_10510	COG0105	UTP biosynthetic process
G4O42_10515	COG0142	geranyltranstransferase activity
G4O42_10525	COG0142	geranyltranstransferase activity
G4O42_10540	COG0776	regulation of translation
G4O42_10545	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G4O42_10585	COG0539	negative regulation of cytoplasmic translation
G4O42_10600	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
G4O42_10605	COG2959	enzyme of heme biosynthesis
G4O42_10610	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_10610	COG3773	Cell wall hydrolase
G4O42_10615	COG2339	peptidase activity
G4O42_10620	COG0492	ferredoxin-NADP+ reductase activity
G4O42_10625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4O42_10630	COG4862	establishment of competence for transformation
G4O42_10635	COG1408	metallophosphoesterase
G4O42_10645	COG1388	LysM domain
G4O42_10650	COG1266	CAAX protease self-immunity
G4O42_10655	COG0514	ATP-dependent DNA helicase (RecQ)
G4O42_10660	COG4955	Helix-turn-helix domain
G4O42_10665	COG1141	Ferredoxin
G4O42_10670	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G4O42_10675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G4O42_10685	COG1595	DNA-templated transcription, initiation
G4O42_10690	COG5002	protein histidine kinase activity
G4O42_10695	COG0745	RESPONSE REGULATOR receiver
G4O42_10700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G4O42_10705	COG1333	cytochrome c biogenesis protein
G4O42_10710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_10715	COG1187	pseudouridine synthase activity
G4O42_10720	COG0700	Nucleoside recognition
G4O42_10725	COG2715	membrane protein required for spore maturation
G4O42_10730	COG1686	Belongs to the peptidase S11 family
G4O42_10755	COG1547	Domain of unknown function (DUF309)
G4O42_10760	COG0456	acetyltransferase
G4O42_10775	COG0307	riboflavin synthase, alpha
G4O42_10780	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4O42_10780	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G4O42_10790	COG0681	Belongs to the peptidase S26 family
G4O42_10800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G4O42_10805	COG4086	secreted protein
G4O42_10810	COG0019	diaminopimelate decarboxylase activity
G4O42_10815	COG0697	spore germination
G4O42_10830	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G4O42_10850	COG1191	sigma factor activity
G4O42_10860	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_10865	COG1686	Belongs to the peptidase S11 family
G4O42_10870	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G4O42_10875	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G4O42_10880	COG4974	Belongs to the 'phage' integrase family
G4O42_10890	COG0735	belongs to the Fur family
G4O42_10895	COG1300	Membrane
G4O42_10910	COG0281	malic enzyme
G4O42_10915	COG1757	Na H antiporter
G4O42_10920	COG1027	Aspartate ammonia-lyase
G4O42_10925	COG0252	asparaginase activity
G4O42_10930	COG1396	sequence-specific DNA binding
G4O42_10935	COG1379	DNA repair
G4O42_10940	COG0494	nUDIX hydrolase
G4O42_10950	COG0667	Aldo Keto reductase
G4O42_10960	COG1073	alpha beta
G4O42_10970	COG4918	Iron-sulphur cluster biosynthesis
G4O42_10975	COG0456	acetyltransferase
G4O42_10975	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G4O42_10980	COG2329	Antibiotic biosynthesis monooxygenase
G4O42_10985	COG0456	acetyltransferase
G4O42_10990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G4O42_11005	COG0628	permease
G4O42_11015	COG0346	lactoylglutathione lyase activity
G4O42_11025	COG3048	D-serine ammonia-lyase activity
G4O42_11030	COG0300	oxidoreductase activity
G4O42_11035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_11040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4O42_11045	COG1024	Enoyl-CoA hydratase
G4O42_11050	COG3425	synthase
G4O42_11055	COG2124	cytochrome p450
G4O42_11060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_11060	COG3321	synthase
G4O42_11060	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_11060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_11065	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_11065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_11065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_11065	COG3321	synthase
G4O42_11070	COG3321	synthase
G4O42_11070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_11070	COG0300	oxidoreductase activity
G4O42_11070	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_11070	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11075	COG3321	synthase
G4O42_11075	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_11075	COG0300	oxidoreductase activity
G4O42_11075	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_11080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_11080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_11080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_11080	COG3321	synthase
G4O42_11080	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11085	COG0300	oxidoreductase activity
G4O42_11085	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_11085	COG3321	synthase
G4O42_11085	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_11090	COG3321	synthase
G4O42_11090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G4O42_11090	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_11090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_11095	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_11100	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_11115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G4O42_11115	COG2070	2-Nitropropane dioxygenase
G4O42_11120	COG0250	Participates in transcription elongation, termination and antitermination
G4O42_11140	COG0596	Alpha beta hydrolase
G4O42_11155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G4O42_11160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G4O42_11175	COG0706	membrane insertase activity
G4O42_11180	COG2195	Cleaves the N-terminal amino acid of tripeptides
G4O42_11185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G4O42_11190	COG0346	lactoylglutathione lyase activity
G4O42_11205	COG4129	membrane
G4O42_11210	COG1126	abc transporter atp-binding protein
G4O42_11215	COG0765	amino acid transport
G4O42_11220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_11230	COG1597	lipid kinase activity
G4O42_11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
G4O42_11240	COG0022	dehydrogenase e1 component
G4O42_11245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G4O42_11250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G4O42_11255	COG3426	butyrate kinase activity
G4O42_11260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4O42_11265	COG0280	phosphate acetyltransferase
G4O42_11270	COG3829	transcription factor binding
G4O42_11270	COG3290	protein histidine kinase activity
G4O42_11280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G4O42_11285	COG2079	MmgE PrpD family protein
G4O42_11290	COG0372	Belongs to the citrate synthase family
G4O42_11295	COG1960	acyl-CoA dehydrogenase activity
G4O42_11300	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4O42_11305	COG0183	Belongs to the thiolase family
G4O42_11310	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_11315	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_11335	COG1902	pentaerythritol trinitrate reductase activity
G4O42_11350	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G4O42_11355	COG0745	RESPONSE REGULATOR receiver
G4O42_11360	COG0750	zinc metalloprotease
G4O42_11365	COG0497	DNA recombination
G4O42_11375	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G4O42_11385	COG0142	geranyltranstransferase activity
G4O42_11395	COG1570	exodeoxyribonuclease VII activity
G4O42_11410	COG1302	Protein conserved in bacteria
G4O42_11415	COG0439	Biotin carboxylase
G4O42_11420	COG0511	ligase activity, forming carbon-carbon bonds
G4O42_11460	COG3854	ATPases associated with a variety of cellular activities
G4O42_11475	COG0006	proline dipeptidase activity
G4O42_11485	COG3872	metal-dependent enzyme
G4O42_11495	COG1752	Esterase of the alpha-beta hydrolase superfamily
G4O42_11510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_11530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4O42_11545	COG1396	sequence-specific DNA binding
G4O42_11555	COG0681	Belongs to the peptidase S26 family
G4O42_11580	COG4940	Competence protein ComGF
G4O42_11590	COG4970	Tfp pilus assembly protein FimT
G4O42_11595	COG4537	Required for transformation and DNA binding
G4O42_11600	COG1459	type II secretion system
G4O42_11605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G4O42_11610	COG0598	Magnesium transport protein CorA
G4O42_11615	COG1253	flavin adenine dinucleotide binding
G4O42_11620	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_11630	COG1393	Belongs to the ArsC family
G4O42_11640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_11650	COG0011	TIGRFAM Protein of
G4O42_11660	COG2866	Carboxypeptidase
G4O42_11665	COG1940	carbohydrate kinase activity
G4O42_11670	COG4483	Protein conserved in bacteria
G4O42_11675	COG1757	Na H antiporter
G4O42_11685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G4O42_11700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4O42_11705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4O42_11710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G4O42_11715	COG0581	inorganic phosphate transmembrane transporter activity
G4O42_11720	COG0573	inorganic phosphate transmembrane transporter activity
G4O42_11725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G4O42_11735	COG0477	Major facilitator Superfamily
G4O42_11740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G4O42_11745	COG2839	Protein conserved in bacteria
G4O42_11750	COG5521	maltodextrose utilization protein MalA
G4O42_11755	COG1388	LysM domain
G4O42_11765	COG4709	membrane
G4O42_11770	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
G4O42_11775	COG0735	belongs to the Fur family
G4O42_11780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_11795	COG0513	Belongs to the DEAD box helicase family
G4O42_11810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G4O42_11815	COG2384	SAM-dependent methyltransferase
G4O42_11820	COG2010	Cytochrome c
G4O42_11825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G4O42_11830	COG0358	DNA primase activity
G4O42_11845	COG0517	IMP dehydrogenase activity
G4O42_11850	COG0751	glycine-tRNA ligase activity
G4O42_11870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G4O42_11875	COG0295	cytidine deaminase activity
G4O42_11880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G4O42_11890	COG1480	7TM receptor with intracellular HD hydrolase
G4O42_11895	COG1702	phosphate starvation-inducible protein PhoH
G4O42_11900	COG0561	phosphatase activity
G4O42_11915	COG4864	UPF0365 protein
G4O42_11920	COG1030	water channel activity
G4O42_11925	COG1610	YqeY-like protein
G4O42_11935	COG1283	sodium-dependent phosphate transmembrane transporter activity
G4O42_11940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G4O42_11945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G4O42_11975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G4O42_11990	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_12005	COG1466	dna polymerase III delta subunit
G4O42_12020	COG0658	competence protein
G4O42_12020	COG2333	competence protein COMEC
G4O42_12025	COG2131	deaminase
G4O42_12030	COG1555	photosystem II stabilization
G4O42_12030	COG1596	polysaccharide export
G4O42_12035	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G4O42_12040	COG2226	methyltransferase
G4O42_12045	COG0799	negative regulation of ribosome biogenesis
G4O42_12050	COG1713	HD superfamily hydrolase involved in NAD metabolism
G4O42_12060	COG1534	Rna-binding protein
G4O42_12065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G4O42_12070	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G4O42_12075	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
G4O42_12085	COG2755	lipolytic protein G-D-S-L family
G4O42_12095	COG0398	Pfam SNARE associated Golgi protein
G4O42_12120	COG1794	racemase activity, acting on amino acids and derivatives
G4O42_12135	COG1733	regulation of RNA biosynthetic process
G4O42_12140	COG0656	L-ascorbic acid biosynthetic process
G4O42_12170	COG3677	Transposase
G4O42_12210	COG5002	protein histidine kinase activity
G4O42_12210	COG0642	Histidine kinase
G4O42_12215	COG0745	RESPONSE REGULATOR receiver
G4O42_12220	COG2311	Membrane
G4O42_12230	COG0454	-acetyltransferase
G4O42_12235	COG0563	adenylate kinase activity
G4O42_12245	COG2814	Major facilitator Superfamily
G4O42_12255	COG0456	acetyltransferase
G4O42_12260	COG2318	DinB family
G4O42_12270	COG0561	phosphatase activity
G4O42_12275	COG0561	phosphatase activity
G4O42_12285	COG1482	cell wall glycoprotein biosynthetic process
G4O42_12290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_12290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_12290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G4O42_12295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_12295	COG3711	transcriptional antiterminator
G4O42_12305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G4O42_12310	COG0583	DNA-binding transcription factor activity
G4O42_12315	COG2814	Major facilitator Superfamily
G4O42_12320	COG2124	cytochrome p450
G4O42_12320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4O42_12325	COG1309	transcriptional regulator
G4O42_12330	COG2226	methyltransferase
G4O42_12340	COG2116	formate transmembrane transporter activity
G4O42_12345	COG5609	conserved protein (DUF2294)
G4O42_12350	COG3383	formate dehydrogenase (NAD+) activity
G4O42_12355	COG2427	Protein of unknown function (DUF1641)
G4O42_12365	COG0626	cystathionine gamma-synthase activity
G4O42_12370	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4O42_12395	COG0768	penicillin binding
G4O42_12420	COG4122	O-methyltransferase activity
G4O42_12425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G4O42_12450	COG0628	permease
G4O42_12455	COG1126	abc transporter atp-binding protein
G4O42_12460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_12465	COG0765	amino acid transport
G4O42_12470	COG0765	amino acid transport
G4O42_12485	COG3881	PFAM PRC-barrel domain
G4O42_12490	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G4O42_12495	COG0457	Tetratricopeptide repeat
G4O42_12505	COG1104	cysteine desulfurase activity
G4O42_12510	COG1959	2 iron, 2 sulfur cluster binding
G4O42_12515	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G4O42_12520	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G4O42_12545	COG3103	Sh3 type 3 domain protein
G4O42_12545	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_12545	COG4991	sh3 domain protein
G4O42_12555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G4O42_12565	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G4O42_12565	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G4O42_12570	COG5416	Lipopolysaccharide assembly protein A domain
G4O42_12575	COG0490	domain, Protein
G4O42_12580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4O42_12580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G4O42_12590	COG2244	polysaccharide biosynthetic process
G4O42_12595	COG2323	membrane
G4O42_12605	COG1862	Preprotein translocase
G4O42_12645	COG1388	LysM domain
G4O42_12655	COG0157	Belongs to the NadC ModD family
G4O42_12660	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G4O42_12665	COG1104	cysteine desulfurase activity
G4O42_12670	COG1827	regulation of RNA biosynthetic process
G4O42_12675	COG0077	Prephenate dehydratase
G4O42_12690	COG3290	protein histidine kinase activity
G4O42_12695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G4O42_12700	COG2868	ribosomal protein
G4O42_12710	COG1994	Peptidase M50
G4O42_12715	COG0739	heme binding
G4O42_12720	COG2894	cell division
G4O42_12725	COG0850	regulation of cytokinetic process
G4O42_12730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G4O42_12740	COG1077	Cell shape determining protein MreB Mrl
G4O42_12760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G4O42_12765	COG0285	dihydrofolate synthase activity
G4O42_12770	COG0525	valine-tRNA ligase activity
G4O42_12780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4O42_12785	COG1388	LysM domain
G4O42_12795	COG0113	porphobilinogen synthase activity
G4O42_12800	COG1587	Uroporphyrinogen-III synthase
G4O42_12810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G4O42_12830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G4O42_12835	COG0470	DNA polymerase III
G4O42_12835	COG1067	ATP-dependent peptidase activity
G4O42_12850	COG0457	Tetratricopeptide repeat
G4O42_12850	COG1477	protein flavinylation
G4O42_12865	COG0473	3-isopropylmalate dehydrogenase activity
G4O42_12880	COG0440	acetolactate synthase activity
G4O42_12885	COG0028	Belongs to the TPP enzyme family
G4O42_12910	COG0622	Phosphoesterase
G4O42_12915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G4O42_12925	COG5401	PFAM Sporulation and spore germination
G4O42_12935	COG1846	Transcriptional regulator
G4O42_12940	COG2197	response regulator
G4O42_12945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G4O42_12950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G4O42_12980	COG5444	nuclease activity
G4O42_13000	COG5632	N-Acetylmuramoyl-L-alanine amidase
G4O42_13005	COG4824	toxin secretion phage lysis holin
G4O42_13060	COG3953	SLT domain
G4O42_13060	COG5280	Phage tail tape measure protein TP901
G4O42_13135	COG5484	DNA packaging
G4O42_13145	COG3677	Transposase
G4O42_13230	COG1484	DNA-dependent DNA replication
G4O42_13235	COG3935	DnaD domain protein
G4O42_13240	COG3723	Recombinational DNA repair protein, rece pathway
G4O42_13245	COG5377	YqaJ viral recombinase family
G4O42_13275	COG3617	BRO family, N-terminal domain
G4O42_13290	COG3620	sequence-specific DNA binding
G4O42_13295	COG1525	nuclease
G4O42_13305	COG2856	Zn peptidase
G4O42_13310	COG2197	response regulator
G4O42_13315	COG0824	Thioesterase
G4O42_13320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G4O42_13325	COG1053	succinate dehydrogenase
G4O42_13330	COG2009	succinate dehydrogenase
G4O42_13335	COG1719	4-vinyl reductase, 4VR
G4O42_13340	COG0527	aspartate kinase activity
G4O42_13350	COG3118	belongs to the thioredoxin family
G4O42_13355	COG3534	alpha-L-arabinofuranosidase
G4O42_13360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G4O42_13365	COG2086	electron transfer activity
G4O42_13370	COG1024	Enoyl-CoA hydratase
G4O42_13375	COG1309	transcriptional regulator
G4O42_13380	COG0318	PFAM AMP-dependent synthetase and ligase
G4O42_13390	COG3766	membrane
G4O42_13400	COG1796	DNA polymerase
G4O42_13400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G4O42_13405	COG1286	toxin biosynthetic process
G4O42_13420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_13420	COG0072	phenylalanine-tRNA ligase activity
G4O42_13425	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G4O42_13430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G4O42_13440	COG3835	regulator
G4O42_13445	COG0277	FAD linked oxidase domain protein
G4O42_13450	COG0247	lactate metabolic process
G4O42_13455	COG1966	Carbon starvation protein
G4O42_13460	COG3534	alpha-L-arabinofuranosidase
G4O42_13465	COG0395	ABC-type sugar transport system, permease component
G4O42_13470	COG1175	transmembrane transport
G4O42_13475	COG1653	transport
G4O42_13485	COG0647	UMP catabolic process
G4O42_13490	COG0235	Class ii aldolase
G4O42_13495	COG1069	ribulokinase activity
G4O42_13500	COG2160	L-arabinose isomerase activity
G4O42_13505	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_13510	COG1363	Peptidase, m42
G4O42_13520	COG3326	Membrane
G4O42_13535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G4O42_13540	COG1346	cytolysis
G4O42_13545	COG1380	Effector of murein hydrolase LrgA
G4O42_13550	COG3279	Response regulator of the LytR AlgR family
G4O42_13555	COG3275	phosphorelay sensor kinase activity
G4O42_13560	COG1011	Hydrolase
G4O42_13575	COG0398	Pfam SNARE associated Golgi protein
G4O42_13580	COG1484	DNA-dependent DNA replication
G4O42_13585	COG3611	Membrane attachment protein
G4O42_13600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4O42_13605	COG1733	regulation of RNA biosynthetic process
G4O42_13610	COG2814	Major facilitator Superfamily
G4O42_13615	COG0656	L-ascorbic acid biosynthetic process
G4O42_13620	COG0237	dephospho-CoA kinase activity
G4O42_13625	COG1971	Probably functions as a manganese efflux pump
G4O42_13630	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G4O42_13635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4O42_13635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G4O42_13640	COG5002	protein histidine kinase activity
G4O42_13645	COG0745	RESPONSE REGULATOR receiver
G4O42_13655	COG0538	isocitrate dehydrogenase activity
G4O42_13660	COG0372	Belongs to the citrate synthase family
G4O42_13685	COG0628	permease
G4O42_13690	COG3030	protein affecting phage T7 exclusion by the F plasmid
G4O42_13695	COG0469	pyruvate kinase activity
G4O42_13715	COG0281	malic enzyme
G4O42_13720	COG0587	DNA-directed DNA polymerase activity
G4O42_13740	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G4O42_13750	COG4109	DRTGG domain
G4O42_13760	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_13775	COG0521	Mo-molybdopterin cofactor biosynthetic process
G4O42_13785	COG0827	DNA restriction-modification system
G4O42_13790	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G4O42_13795	COG3874	Sporulation protein YtfJ
G4O42_13805	COG1714	RDD family
G4O42_13810	COG0616	signal peptide processing
G4O42_13815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G4O42_13820	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G4O42_13825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4O42_13840	COG1104	cysteine desulfurase activity
G4O42_13845	COG1114	Component of the transport system for branched-chain amino acids
G4O42_13855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G4O42_13860	COG1309	transcriptional regulator
G4O42_13865	COG1956	GAF domain-containing protein
G4O42_13870	COG2199	diguanylate cyclase activity
G4O42_13870	COG2203	Gaf domain
G4O42_13885	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_13890	COG4282	regulation of fungal-type cell wall biogenesis
G4O42_13935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4O42_13935	COG1017	nitric oxide dioxygenase activity
G4O42_13950	COG0693	protein deglycase activity
G4O42_13965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G4O42_13970	COG1378	Sugar-specific transcriptional regulator TrmB
G4O42_13990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G4O42_13995	COG0454	-acetyltransferase
G4O42_14000	COG0517	IMP dehydrogenase activity
G4O42_14005	COG0123	including yeast histone deacetylase and acetoin utilization protein
G4O42_14010	COG1360	Flagellar Motor Protein
G4O42_14015	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G4O42_14020	COG1609	Transcriptional regulator
G4O42_14025	COG1605	Chorismate mutase
G4O42_14025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G4O42_14030	COG3118	belongs to the thioredoxin family
G4O42_14035	COG4980	gas vesicle protein
G4O42_14040	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
G4O42_14050	COG1674	ftsk spoiiie
G4O42_14055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G4O42_14065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_14075	COG1363	Peptidase, m42
G4O42_14080	COG5584	Small secreted protein
G4O42_14085	COG0281	malic enzyme
G4O42_14090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G4O42_14105	COG0510	thiamine kinase activity
G4O42_14110	COG1597	lipid kinase activity
G4O42_14120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G4O42_14125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G4O42_14130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_14135	COG2252	PERMEase
G4O42_14140	COG4473	ABC transporter
G4O42_14145	COG1131	(ABC) transporter
G4O42_14150	COG1349	DNA-binding transcription factor activity
G4O42_14155	COG1187	pseudouridine synthase activity
G4O42_14160	COG2244	polysaccharide biosynthetic process
G4O42_14165	COG2081	HI0933 family
G4O42_14170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G4O42_14180	COG1609	Transcriptional regulator
G4O42_14185	COG1653	transport
G4O42_14190	COG1175	transmembrane transport
G4O42_14195	COG0395	ABC-type sugar transport system, permease component
G4O42_14200	COG1486	melibiose metabolic process
G4O42_14210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G4O42_14225	COG2202	Pas domain
G4O42_14225	COG1366	Belongs to the anti-sigma-factor antagonist family
G4O42_14230	COG2814	Major facilitator Superfamily
G4O42_14235	COG5522	Integral membrane protein (intg_mem_TP0381)
G4O42_14240	COG0577	efflux transmembrane transporter activity
G4O42_14245	COG1136	(ABC) transporter
G4O42_14250	COG2205	protein histidine kinase activity
G4O42_14255	COG0745	RESPONSE REGULATOR receiver
G4O42_14260	COG0577	efflux transmembrane transporter activity
G4O42_14265	COG1136	(ABC) transporter
G4O42_14285	COG1131	(ABC) transporter
G4O42_14290	COG1725	Transcriptional regulator
G4O42_14300	COG1242	4 iron, 4 sulfur cluster binding
G4O42_14305	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
G4O42_14315	COG0584	glycerophosphoryl diester phosphodiesterase
G4O42_14325	COG2267	carboxylic ester hydrolase activity
G4O42_14330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G4O42_14335	COG1113	amino acid transport
G4O42_14340	COG0367	asparagine synthase
G4O42_14360	COG1506	peptidase
G4O42_14365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G4O42_14370	COG1116	anion transmembrane transporter activity
G4O42_14375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G4O42_14380	COG0494	nUDIX hydrolase
G4O42_14385	COG4824	toxin secretion phage lysis holin
G4O42_14390	COG0783	Belongs to the Dps family
G4O42_14415	COG0288	reversible hydration of carbon dioxide
G4O42_14425	COG1271	oxidase subunit
G4O42_14430	COG1294	oxidase, subunit
G4O42_14445	COG4948	Mandelate Racemase Muconate Lactonizing
G4O42_14455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G4O42_14460	COG0596	Alpha beta hydrolase
G4O42_14470	COG1169	isochorismate synthase
G4O42_14475	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G4O42_14480	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
G4O42_14605	COG3859	Proton-coupled thiamine transporter YuaJ
G4O42_14610	COG2268	Band 7 protein
G4O42_14615	COG1585	Membrane protein implicated in regulation of membrane protease activity
G4O42_14620	COG2318	DinB family
G4O42_14630	COG1454	alcohol dehydrogenase
G4O42_14635	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_14640	COG1510	regulation of RNA biosynthetic process
G4O42_14650	COG0569	domain protein
G4O42_14655	COG1705	Flagellar rod assembly protein muramidase FlgJ
G4O42_14660	COG1017	nitric oxide dioxygenase activity
G4O42_14660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G4O42_14685	COG0628	permease
G4O42_14690	COG0673	inositol 2-dehydrogenase activity
G4O42_14695	COG0693	protein deglycase activity
G4O42_14700	COG0840	transmembrane signaling receptor activity
G4O42_14705	COG0840	transmembrane signaling receptor activity
G4O42_14710	COG0840	transmembrane signaling receptor activity
G4O42_14715	COG0840	transmembrane signaling receptor activity
G4O42_14730	COG2070	2-Nitropropane dioxygenase
G4O42_14735	COG0432	Pfam Uncharacterised protein family UPF0047
G4O42_14740	COG0366	Alpha amylase catalytic
G4O42_14745	COG1253	flavin adenine dinucleotide binding
G4O42_14750	COG2738	Putative neutral zinc metallopeptidase
G4O42_14765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G4O42_14790	COG1335	isochorismatase
G4O42_14795	COG1979	alcohol dehydrogenase
G4O42_14800	COG1979	alcohol dehydrogenase
G4O42_14805	COG2155	Conserved Protein
G4O42_14810	COG1098	S1 RNA binding domain
G4O42_14815	COG0436	Aminotransferase
G4O42_14820	COG1522	sequence-specific DNA binding
G4O42_14825	COG2267	carboxylic ester hydrolase activity
G4O42_14835	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G4O42_14840	COG2205	protein histidine kinase activity
G4O42_14850	COG5018	Exonuclease
G4O42_14855	COG2814	Major facilitator Superfamily
G4O42_14860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_14865	COG3011	Protein conserved in bacteria
G4O42_14875	COG3290	protein histidine kinase activity
G4O42_14880	COG4565	transcriptional regulatory protein
G4O42_14910	COG2111	Na H antiporter
G4O42_14910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G4O42_14915	COG2111	Na H antiporter
G4O42_14920	COG1006	Multisubunit Na H antiporter MnhC subunit
G4O42_14925	COG0651	ATP synthesis coupled electron transport
G4O42_14930	COG1863	multisubunit Na H antiporter MnhE subunit
G4O42_14935	COG2212	antiporter activity
G4O42_14940	COG1320	monovalent cation:proton antiporter activity
G4O42_14945	COG2050	protein possibly involved in aromatic compounds catabolism
G4O42_14950	COG2197	response regulator
G4O42_14955	COG4585	Histidine kinase
G4O42_14985	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G4O42_14990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G4O42_14995	COG1335	isochorismatase
G4O42_15000	COG5506	Protein of unknown function (DUF1694)
G4O42_15015	COG0628	permease
G4O42_15025	COG1418	mRNA catabolic process
G4O42_15030	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_15040	COG1511	domain protein
G4O42_15045	COG0433	COG0433 Predicted ATPase
G4O42_15045	COG1674	ftsk spoiiie
G4O42_15050	COG4499	WXG100 protein secretion system (Wss), protein YukC
G4O42_15055	COG5417	Belongs to the EsaB family
G4O42_15060	COG4842	Belongs to the WXG100 family
G4O42_15065	COG2508	Transcriptional regulator
G4O42_15065	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G4O42_15070	COG0686	Belongs to the AlaDH PNT family
G4O42_15075	COG5634	Uncharacterized conserved protein (DUF2278)
G4O42_15080	COG3251	PFAM MbtH domain protein
G4O42_15085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G4O42_15090	COG3433	isochorismatase activity
G4O42_15090	COG1535	isochorismatase
G4O42_15095	COG1021	2,3-dihydroxybenzoate-AMP ligase
G4O42_15100	COG1169	isochorismate synthase
G4O42_15105	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_15110	COG2819	hydrolase of the alpha beta superfamily
G4O42_15115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G4O42_15120	COG1268	BioY protein
G4O42_15125	COG2056	Na+-H+ antiporter family
G4O42_15135	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
G4O42_15140	COG3584	3D domain protein
G4O42_15155	COG1252	NADH dehydrogenase
G4O42_15180	COG1131	(ABC) transporter
G4O42_15200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G4O42_15205	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G4O42_15210	COG0316	Belongs to the HesB IscA family
G4O42_15220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4O42_15230	COG1252	NADH dehydrogenase
G4O42_15235	COG4837	Protein of unknown function (DUF1462)
G4O42_15240	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G4O42_15245	COG4946	Tricorn protease homolog
G4O42_15245	COG0823	Involved in the tonB-independent uptake of proteins
G4O42_15245	COG1506	peptidase
G4O42_15255	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G4O42_15260	COG0460	homoserine dehydrogenase
G4O42_15265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G4O42_15270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G4O42_15275	COG0647	UMP catabolic process
G4O42_15280	COG2445	Protein of unknown function DUF86
G4O42_15285	COG4470	Protein conserved in bacteria
G4O42_15295	COG0739	heme binding
G4O42_15305	COG0737	Belongs to the 5'-nucleotidase family
G4O42_15310	COG0730	response to heat
G4O42_15315	COG1801	Protein of unknown function DUF72
G4O42_15330	COG2508	Transcriptional regulator
G4O42_15350	COG2814	Major facilitator Superfamily
G4O42_15355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G4O42_15360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G4O42_15365	COG2356	endonuclease I
G4O42_15370	COG3842	ATPase activity
G4O42_15375	COG2188	Transcriptional regulator
G4O42_15380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4O42_15385	COG0395	ABC-type sugar transport system, permease component
G4O42_15390	COG1175	transmembrane transport
G4O42_15395	COG1653	transport
G4O42_15400	COG2222	sugar isomerase
G4O42_15405	COG0789	Transcriptional regulator
G4O42_15430	COG0322	excinuclease ABC activity
G4O42_15435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G4O42_15455	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_15460	COG0719	Fe-S assembly protein
G4O42_15465	COG0822	iron-sulfur transferase activity
G4O42_15470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G4O42_15475	COG0719	Fe-S assembly protein
G4O42_15480	COG0396	ATPase activity
G4O42_15490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4O42_15495	COG1464	Belongs to the NlpA lipoprotein family
G4O42_15500	COG2011	ABC-type metal ion transport system permease component
G4O42_15505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G4O42_15515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G4O42_15520	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G4O42_15535	COG1393	Belongs to the ArsC family
G4O42_15540	COG1960	acyl-CoA dehydrogenase activity
G4O42_15545	COG0183	Belongs to the thiolase family
G4O42_15550	COG1250	3-hydroxyacyl-CoA dehydrogenase
G4O42_15550	COG1024	Enoyl-CoA hydratase
G4O42_15570	COG5577	PFAM Coat F domain
G4O42_15575	COG1846	Transcriptional regulator
G4O42_15580	COG0477	Major facilitator Superfamily
G4O42_15585	COG1942	4-Oxalocrotonate Tautomerase
G4O42_15590	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_15595	COG0583	DNA-binding transcription factor activity
G4O42_15605	COG0583	DNA-binding transcription factor activity
G4O42_15625	COG1120	ATPase activity
G4O42_15640	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_15645	COG0783	Belongs to the Dps family
G4O42_15650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_15655	COG0745	RESPONSE REGULATOR receiver
G4O42_15660	COG2205	protein histidine kinase activity
G4O42_15660	COG2770	Histidine kinase
G4O42_15670	COG1309	transcriptional regulator
G4O42_15675	COG0114	fumarate hydratase activity
G4O42_15685	COG0697	spore germination
G4O42_15690	COG0814	amino acid
G4O42_15700	COG2197	response regulator
G4O42_15705	COG4585	Histidine kinase
G4O42_15710	COG4758	membrane
G4O42_15715	COG3595	metallopeptidase activity
G4O42_15720	COG1842	Phage shock protein A
G4O42_15725	COG4758	membrane
G4O42_15730	COG2814	Major facilitator Superfamily
G4O42_15735	COG2096	Adenosyltransferase
G4O42_15740	COG1120	ATPase activity
G4O42_15745	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_15750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_15755	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_15760	COG3386	PFAM SMP-30 Gluconolaconase
G4O42_15765	COG2205	protein histidine kinase activity
G4O42_15770	COG0745	RESPONSE REGULATOR receiver
G4O42_15780	COG1191	sigma factor activity
G4O42_15790	COG2140	Oxalate decarboxylase
G4O42_15800	COG1120	ATPase activity
G4O42_15805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_15810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_15815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_15820	COG0531	amino acid
G4O42_15830	COG1988	membrane-bound metal-dependent
G4O42_15835	COG1368	sulfuric ester hydrolase activity
G4O42_15840	COG1910	domain protein
G4O42_15845	COG0725	ABC transporter, periplasmic molybdate-binding protein
G4O42_15850	COG4149	molybdate abc transporter
G4O42_15855	COG2197	response regulator
G4O42_15860	COG3850	Histidine kinase
G4O42_15865	COG1131	(ABC) transporter
G4O42_15875	COG0842	Transport permease protein
G4O42_15880	COG0656	L-ascorbic acid biosynthetic process
G4O42_15900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G4O42_15905	COG3973	AAA domain
G4O42_15910	COG2860	membrane
G4O42_15920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G4O42_15925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G4O42_15930	COG2217	Heavy metal translocating P-type atpase
G4O42_15935	COG2217	Heavy metal translocating P-type atpase
G4O42_15940	COG2608	mercury ion transmembrane transporter activity
G4O42_15945	COG1937	Protein conserved in bacteria
G4O42_15950	COG0673	inositol 2-dehydrogenase activity
G4O42_15960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_15965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G4O42_15970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_15975	COG1126	abc transporter atp-binding protein
G4O42_15980	COG0765	amino acid transport
G4O42_15985	COG0765	amino acid transport
G4O42_15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_15995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G4O42_16000	COG0454	-acetyltransferase
G4O42_16005	COG0583	DNA-binding transcription factor activity
G4O42_16010	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_16050	COG0557	exoribonuclease II activity
G4O42_16055	COG1647	Serine aminopeptidase, S33
G4O42_16060	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G4O42_16065	COG1476	TRANSCRIPTIONal
G4O42_16070	COG1396	sequence-specific DNA binding
G4O42_16075	COG1396	sequence-specific DNA binding
G4O42_16080	COG1733	regulation of RNA biosynthetic process
G4O42_16105	COG1131	(ABC) transporter
G4O42_16110	COG1174	glycine betaine transport
G4O42_16115	COG1732	Glycine betaine
G4O42_16120	COG1174	glycine betaine transport
G4O42_16125	COG1125	glycine betaine transport
G4O42_16125	COG0517	IMP dehydrogenase activity
G4O42_16130	COG1510	regulation of RNA biosynthetic process
G4O42_16135	COG1174	glycine betaine transport
G4O42_16140	COG1732	Glycine betaine
G4O42_16145	COG1174	glycine betaine transport
G4O42_16150	COG0517	IMP dehydrogenase activity
G4O42_16150	COG1125	glycine betaine transport
G4O42_16155	COG1510	regulation of RNA biosynthetic process
G4O42_16160	COG2095	MarC family integral membrane protein
G4O42_16165	COG3064	Membrane
G4O42_16170	COG4640	response to antibiotic
G4O42_16175	COG0456	acetyltransferase
G4O42_16190	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G4O42_16210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G4O42_16215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4O42_16225	COG2234	aminopeptidase activity
G4O42_16245	COG0126	phosphoglycerate kinase activity
G4O42_16250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G4O42_16255	COG2390	Transcriptional regulator
G4O42_16260	COG2814	Major facilitator Superfamily
G4O42_16265	COG1609	Transcriptional regulator
G4O42_16270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_16280	COG0583	DNA-binding transcription factor activity
G4O42_16285	COG0697	spore germination
G4O42_16290	COG1113	amino acid transport
G4O42_16295	COG1609	Transcriptional regulator
G4O42_16305	COG0561	phosphatase activity
G4O42_16310	COG1737	Transcriptional regulator
G4O42_16315	COG1070	Carbohydrate kinase
G4O42_16355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_16360	COG2186	Transcriptional regulator
G4O42_16365	COG1620	l-lactate permease
G4O42_16370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G4O42_16380	COG5039	Polysaccharide pyruvyl transferase
G4O42_16385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4O42_16390	COG0110	maltose O-acetyltransferase activity
G4O42_16395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G4O42_16400	COG2244	polysaccharide biosynthetic process
G4O42_16405	COG1216	Glycosyl transferase, family 2
G4O42_16410	COG5039	Polysaccharide pyruvyl transferase
G4O42_16415	COG1216	Glycosyl transferase, family 2
G4O42_16425	COG0438	transferase activity, transferring glycosyl groups
G4O42_16430	COG1215	transferase activity, transferring glycosyl groups
G4O42_16435	COG0438	transferase activity, transferring glycosyl groups
G4O42_16440	COG1086	Polysaccharide biosynthesis protein
G4O42_16445	COG0489	protein tyrosine kinase activity
G4O42_16450	COG3944	biosynthesis protein
G4O42_16455	COG1396	sequence-specific DNA binding
G4O42_16460	COG2272	Belongs to the type-B carboxylesterase lipase family
G4O42_16465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G4O42_16470	COG2364	Membrane
G4O42_16475	COG0456	acetyltransferase
G4O42_16480	COG3479	Phenolic acid decarboxylase
G4O42_16530	COG2223	nitrite transmembrane transporter activity
G4O42_16535	COG1609	Transcriptional regulator
G4O42_16545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G4O42_16550	COG0366	Alpha amylase catalytic
G4O42_16555	COG1554	hydrolase, family 65, central catalytic
G4O42_16560	COG5521	maltodextrose utilization protein MalA
G4O42_16565	COG3833	ABC-type maltose transport systems, permease component
G4O42_16570	COG1175	transmembrane transport
G4O42_16575	COG2182	Extracellular solute-binding protein
G4O42_16580	COG0366	Alpha amylase catalytic
G4O42_16585	COG1609	Transcriptional regulator
G4O42_16590	COG1611	Belongs to the LOG family
G4O42_16595	COG1694	Mazg nucleotide pyrophosphohydrolase
G4O42_16600	COG0659	secondary active sulfate transmembrane transporter activity
G4O42_16605	COG0288	reversible hydration of carbon dioxide
G4O42_16610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G4O42_16615	COG4290	ribonuclease
G4O42_16620	COG2162	N-hydroxyarylamine O-acetyltransferase activity
G4O42_16625	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_16635	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G4O42_16645	COG1051	belongs to the nudix hydrolase family
G4O42_16650	COG0492	ferredoxin-NADP+ reductase activity
G4O42_16655	COG3883	PFAM NLP P60 protein
G4O42_16655	COG0791	NLP P60 protein
G4O42_16660	COG0457	Tetratricopeptide repeat
G4O42_16665	COG5002	protein histidine kinase activity
G4O42_16670	COG0745	RESPONSE REGULATOR receiver
G4O42_16675	COG1132	(ABC) transporter
G4O42_16680	COG0140	phosphoribosyl-ATP diphosphatase activity
G4O42_16680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G4O42_16705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G4O42_16720	COG4990	cell redox homeostasis
G4O42_16725	COG0110	maltose O-acetyltransferase activity
G4O42_16745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G4O42_16755	COG2188	Transcriptional regulator
G4O42_16760	COG1309	transcriptional regulator
G4O42_16765	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G4O42_16770	COG1950	PFAM Membrane protein of
G4O42_16775	COG1983	PspC domain protein
G4O42_16780	COG3595	metallopeptidase activity
G4O42_16795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G4O42_16805	COG4897	Protein conserved in bacteria
G4O42_16810	COG3848	Pyruvate phosphate dikinase
G4O42_16810	COG0574	Belongs to the PEP-utilizing enzyme family
G4O42_16815	COG1309	transcriptional regulator
G4O42_16820	COG2814	Major facilitator Superfamily
G4O42_16835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_16845	COG3409	Peptidoglycan-binding domain 1 protein
G4O42_16845	COG0793	Belongs to the peptidase S41A family
G4O42_16850	COG3420	alginic acid biosynthetic process
G4O42_16855	COG2177	Part of the ABC transporter FtsEX involved in
G4O42_16860	COG2884	Cell division ATP-binding protein ftsE
G4O42_16865	COG2010	Cytochrome c
G4O42_16870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_16885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G4O42_16900	COG1516	flagellar protein fliS
G4O42_16905	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G4O42_16910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4O42_16930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G4O42_16935	COG4786	Flagellar basal body rod
G4O42_16935	COG1256	bacterial-type flagellum assembly
G4O42_16940	COG3418	PFAM FlgN family protein
G4O42_16945	COG2747	anti-sigma28 factor FlgM
G4O42_16955	COG1040	competence protein
G4O42_16965	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
G4O42_16970	COG1307	EDD domain protein, DegV family
G4O42_16975	COG2197	response regulator
G4O42_16980	COG4585	Histidine kinase
G4O42_16985	COG1739	Uncharacterized protein family UPF0029
G4O42_16990	COG1316	TRANSCRIPTIONal
G4O42_16995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G4O42_17000	COG0438	transferase activity, transferring glycosyl groups
G4O42_17005	COG1215	transferase activity, transferring glycosyl groups
G4O42_17010	COG3206	protein involved in exopolysaccharide biosynthesis
G4O42_17015	COG3307	-O-antigen
G4O42_17020	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4O42_17025	COG0438	transferase activity, transferring glycosyl groups
G4O42_17025	COG0297	glycogen (starch) synthase activity
G4O42_17030	COG2244	polysaccharide biosynthetic process
G4O42_17040	COG2247	cell wall binding repeat
G4O42_17040	COG0860	N-Acetylmuramoyl-L-alanine amidase
G4O42_17045	COG2385	sporulation resulting in formation of a cellular spore
G4O42_17045	COG2247	cell wall binding repeat
G4O42_17055	COG1316	TRANSCRIPTIONal
G4O42_17060	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G4O42_17065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G4O42_17070	COG1134	teichoic acid transport
G4O42_17075	COG1682	transport, permease protein
G4O42_17080	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4O42_17090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G4O42_17095	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
G4O42_17100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4O42_17105	COG4193	domain, Protein
G4O42_17110	COG1482	cell wall glycoprotein biosynthetic process
G4O42_17115	COG0697	spore germination
G4O42_17120	COG0814	amino acid
G4O42_17130	COG1215	transferase activity, transferring glycosyl groups
G4O42_17135	COG2814	Major facilitator Superfamily
G4O42_17140	COG1316	TRANSCRIPTIONal
G4O42_17145	COG0561	phosphatase activity
G4O42_17150	COG2433	Pfam Transposase IS66
G4O42_17155	COG0791	NLP P60 protein
G4O42_17165	COG2843	Capsule synthesis protein
G4O42_17175	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G4O42_17180	COG0697	spore germination
G4O42_17185	COG0814	amino acid
G4O42_17195	COG1609	Transcriptional regulator
G4O42_17200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G4O42_17210	COG1129	ABC transporter
G4O42_17215	COG1172	Belongs to the binding-protein-dependent transport system permease family
G4O42_17220	COG1879	ABC-type sugar transport system periplasmic component
G4O42_17225	COG3103	Sh3 type 3 domain protein
G4O42_17230	COG2249	NAD(P)H dehydrogenase (quinone) activity
G4O42_17235	COG3527	Alpha-acetolactate decarboxylase
G4O42_17240	COG0028	Belongs to the TPP enzyme family
G4O42_17245	COG0583	DNA-binding transcription factor activity
G4O42_17250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G4O42_17265	COG5337	Spore coat protein CotH
G4O42_17275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G4O42_17285	COG0405	Gamma-glutamyltransferase
G4O42_17290	COG1522	sequence-specific DNA binding
G4O42_17295	COG2059	Chromate
G4O42_17300	COG2059	Chromate
G4O42_17310	COG0655	NAD(P)H dehydrogenase (quinone) activity
G4O42_17315	COG0583	DNA-binding transcription factor activity
G4O42_17340	COG5444	nuclease activity
G4O42_17355	COG3878	Protein conserved in bacteria
G4O42_17360	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G4O42_17365	COG4464	protein tyrosine phosphatase activity
G4O42_17370	COG0489	protein tyrosine kinase activity
G4O42_17375	COG3944	biosynthesis protein
G4O42_17385	COG4715	Zinc finger, swim domain protein
G4O42_17390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G4O42_17395	COG0561	phosphatase activity
G4O42_17400	COG1349	DNA-binding transcription factor activity
G4O42_17405	COG0629	single-stranded DNA binding
G4O42_17430	COG0457	Tetratricopeptide repeat
G4O42_17435	COG4786	Flagellar basal body rod
G4O42_17440	COG4786	Flagellar basal body rod
G4O42_17445	COG1077	Cell shape determining protein MreB Mrl
G4O42_17450	COG1609	Transcriptional regulator
G4O42_17455	COG1846	Transcriptional regulator
G4O42_17460	COG2814	Major facilitator Superfamily
G4O42_17465	COG1953	Uracil, thiamine, allantoin
G4O42_17470	COG0477	Major facilitator Superfamily
G4O42_17475	COG1335	isochorismatase
G4O42_17480	COG0004	ammonium transporteR
G4O42_17485	COG0347	Belongs to the P(II) protein family
G4O42_17490	COG0772	Belongs to the SEDS family
G4O42_17495	COG0671	phosphoesterase, PA-phosphatase related
G4O42_17505	COG0739	heme binding
G4O42_17510	COG1247	-acetyltransferase
G4O42_17525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4O42_17535	COG0726	polysaccharide deacetylase
G4O42_17545	COG1959	2 iron, 2 sulfur cluster binding
G4O42_17560	COG0831	urea catabolic process
G4O42_17565	COG3237	CsbD-like
G4O42_17570	COG1994	Peptidase M50
G4O42_17575	COG0457	Tetratricopeptide repeat
G4O42_17585	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G4O42_17590	COG2304	oxidoreductase activity
G4O42_17595	COG2304	oxidoreductase activity
G4O42_17600	COG2385	sporulation resulting in formation of a cellular spore
G4O42_17605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4O42_17615	COG4836	Membrane
G4O42_17685	COG0698	ribose 5-phosphate isomerase
G4O42_17690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G4O42_17700	COG0009	L-threonylcarbamoyladenylate synthase
G4O42_17705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G4O42_17725	COG2890	protein-(glutamine-N5) methyltransferase activity
G4O42_17730	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G4O42_17735	COG0346	lactoylglutathione lyase activity
G4O42_17740	COG0789	Transcriptional regulator
G4O42_17745	COG0679	Auxin Efflux Carrier
G4O42_17750	COG0281	malic enzyme
G4O42_17765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G4O42_17770	COG1494	fructose-1,6-bisphosphatase
G4O42_17775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G4O42_17785	COG0191	fructose-bisphosphate aldolase activity
G4O42_17790	COG2204	response regulator
G4O42_17795	COG4821	SIS domain
G4O42_17810	COG2181	nitrate reductase activity
G4O42_17810	COG0247	lactate metabolic process
G4O42_17815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4O42_17830	COG1132	(ABC) transporter
G4O42_17835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G4O42_17845	COG2181	nitrate reductase activity
G4O42_17850	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
G4O42_17855	COG1140	nitrate reductase beta subunit
G4O42_17860	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
G4O42_17865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4O42_17875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G4O42_17880	COG2223	nitrite transmembrane transporter activity
G4O42_17890	COG4506	Protein conserved in bacteria
G4O42_17900	COG3391	amine dehydrogenase activity
G4O42_17905	COG3391	amine dehydrogenase activity
G4O42_17910	COG0457	Tetratricopeptide repeat
G4O42_17920	COG0010	Belongs to the arginase family
G4O42_17925	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G4O42_17930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G4O42_17945	COG1994	Peptidase M50
G4O42_17950	COG1942	4-Oxalocrotonate Tautomerase
G4O42_17955	COG1846	Transcriptional regulator
G4O42_17960	COG0531	amino acid
G4O42_17965	COG3465	dGTPase activity
G4O42_17970	COG1078	dGTPase activity
G4O42_17985	COG1695	Transcriptional regulator
G4O42_17995	COG1131	(ABC) transporter
G4O42_18000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G4O42_18030	COG0583	DNA-binding transcription factor activity
G4O42_18035	COG2855	membrane
G4O42_18040	COG0280	phosphate acetyltransferase
G4O42_18050	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_18055	COG0436	Aminotransferase
G4O42_18085	COG2814	Major facilitator Superfamily
G4O42_18090	COG2814	Major facilitator Superfamily
G4O42_18095	COG0833	amino acid
G4O42_18100	COG4187	Peptidase family M20/M25/M40
G4O42_18105	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_18110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G4O42_18115	COG2205	protein histidine kinase activity
G4O42_18120	COG0745	RESPONSE REGULATOR receiver
G4O42_18135	COG1131	(ABC) transporter
G4O42_18140	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
G4O42_18145	COG1091	dTDP-4-dehydrorhamnose reductase activity
G4O42_18150	COG1088	dTDP-glucose 4,6-dehydratase activity
G4O42_18155	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G4O42_18160	COG3980	spore coat polysaccharide biosynthesis protein
G4O42_18165	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
G4O42_18170	COG2089	acid synthase
G4O42_18175	COG0456	acetyltransferase
G4O42_18180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G4O42_18185	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G4O42_18190	COG0463	Glycosyl transferase, family 2
G4O42_18200	COG2363	Small membrane protein
G4O42_18205	COG2233	PERMEase
G4O42_18220	COG1216	Glycosyl transferase, family 2
G4O42_18235	COG1695	Transcriptional regulator
G4O42_18240	COG0351	phosphomethylpyrimidine kinase
G4O42_18250	COG1621	beta-fructofuranosidase activity
G4O42_18255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G4O42_18255	COG1263	PTS System
G4O42_18260	COG3711	transcriptional antiterminator
G4O42_18270	COG1404	Belongs to the peptidase S8 family
G4O42_18275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G4O42_18280	COG0778	Nitroreductase
G4O42_18285	COG0772	Belongs to the SEDS family
G4O42_18290	COG0454	-acetyltransferase
G4O42_18310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G4O42_18315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G4O42_18320	COG2261	transglycosylase associated protein
G4O42_18325	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G4O42_18330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G4O42_18335	COG2246	polysaccharide biosynthetic process
G4O42_18340	COG1309	transcriptional regulator
G4O42_18360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G4O42_18365	COG2837	iron assimilation
G4O42_18380	COG0583	DNA-binding transcription factor activity
G4O42_18390	COG1346	cytolysis
G4O42_18395	COG4895	conserved protein (DUF2196)
G4O42_18400	COG0789	Transcriptional regulator
G4O42_18405	COG5504	Zn-dependent protease
G4O42_18410	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G4O42_18415	COG0346	lactoylglutathione lyase activity
G4O42_18420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_18425	COG1404	Belongs to the peptidase S8 family
G4O42_18430	COG1442	glycosyl transferase family 8
G4O42_18435	COG2357	RelA SpoT domain protein
G4O42_18440	COG1575	Belongs to the MenA family. Type 1 subfamily
G4O42_18455	COG1696	Membrane protein involved in D-alanine export
G4O42_18465	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
G4O42_18470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G4O42_18475	COG1486	melibiose metabolic process
G4O42_18480	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4O42_18485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_18490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_18495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G4O42_18495	COG3711	transcriptional antiterminator
G4O42_18505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_18510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G4O42_18520	COG0640	Transcriptional regulator
G4O42_18525	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G4O42_18530	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_18535	COG1447	Phosphotransferase system cellobiose-specific component IIA
G4O42_18540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G4O42_18545	COG2723	6-phospho-beta-galactosidase activity
G4O42_18555	COG1482	cell wall glycoprotein biosynthetic process
G4O42_18565	COG0753	catalase activity
G4O42_18570	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
G4O42_18575	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G4O42_18595	COG3279	Response regulator of the LytR AlgR family
G4O42_18615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G4O42_18620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G4O42_18625	COG4988	ABC transporter
G4O42_18630	COG1294	oxidase, subunit
G4O42_18635	COG1271	oxidase subunit
G4O42_18640	COG3493	citrate carrier protein
G4O42_18645	COG0726	polysaccharide deacetylase
G4O42_18650	COG3842	ATPase activity
G4O42_18655	COG2508	Transcriptional regulator
G4O42_18660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_18670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G4O42_18680	COG4894	glucomannan catabolic process
G4O42_18685	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G4O42_18690	COG0500	methyltransferase
G4O42_18695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4O42_18710	COG0693	protein deglycase activity
G4O42_18710	COG0753	catalase activity
G4O42_18715	COG2851	Citrate transporter
G4O42_18720	COG2273	Hydrolase Family 16
G4O42_18730	COG2270	Major facilitator Superfamily
G4O42_18735	COG0513	Belongs to the DEAD box helicase family
G4O42_18745	COG0697	spore germination
G4O42_18750	COG0589	response to stress
G4O42_18805	COG3507	Belongs to the glycosyl hydrolase 43 family
G4O42_18830	COG0010	Belongs to the arginase family
G4O42_18835	COG0833	amino acid
G4O42_18840	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G4O42_18845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G4O42_18855	COG2390	Transcriptional regulator
G4O42_18860	COG0561	phosphatase activity
G4O42_18890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G4O42_18895	COG5294	Protein conserved in bacteria
G4O42_18900	COG0577	efflux transmembrane transporter activity
G4O42_18905	COG1136	(ABC) transporter
G4O42_18910	COG2205	protein histidine kinase activity
G4O42_18915	COG0745	RESPONSE REGULATOR receiver
G4O42_18920	COG2205	protein histidine kinase activity
G4O42_18925	COG0745	RESPONSE REGULATOR receiver
G4O42_18955	COG1082	Xylose isomerase domain protein TIM barrel
G4O42_18965	COG2814	Major facilitator Superfamily
G4O42_18995	COG1349	DNA-binding transcription factor activity
G4O42_19000	COG0667	Aldo Keto reductase
G4O42_19005	COG2814	Major facilitator Superfamily
G4O42_19020	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_19025	COG2197	response regulator
G4O42_19030	COG4585	Histidine kinase
G4O42_19035	COG3239	Fatty acid desaturase
G4O42_19040	COG1309	transcriptional regulator
G4O42_19045	COG1012	belongs to the aldehyde dehydrogenase family
G4O42_19050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G4O42_19060	COG0640	Transcriptional regulator
G4O42_19065	COG2814	Major facilitator Superfamily
G4O42_19070	COG1714	RDD family
G4O42_19080	COG0450	alkyl hydroperoxide reductase
G4O42_19085	COG3634	alkyl hydroperoxide reductase activity
G4O42_19090	COG3177	Filamentation induced by cAMP protein fic
G4O42_19095	COG1113	amino acid transport
G4O42_19105	COG2080	2 iron, 2 sulfur cluster binding
G4O42_19120	COG2068	MobA-Related Protein
G4O42_19125	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G4O42_19180	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
G4O42_19185	COG0667	Aldo Keto reductase
G4O42_19190	COG0456	acetyltransferase
G4O42_19195	COG0457	Tetratricopeptide repeat
G4O42_19200	COG0010	Belongs to the arginase family
G4O42_19205	COG0833	amino acid
G4O42_19210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G4O42_19215	COG5658	integral membrane protein
G4O42_19220	COG0640	Transcriptional regulator
G4O42_19225	COG3829	transcription factor binding
G4O42_19235	COG0488	(ABC) transporter
G4O42_19250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G4O42_19255	COG3850	Histidine kinase
G4O42_19255	COG5002	protein histidine kinase activity
G4O42_19260	COG0745	RESPONSE REGULATOR receiver
G4O42_19265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G4O42_19270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G4O42_19275	COG4853	Protein conserved in bacteria
G4O42_19280	COG4863	YycH protein
G4O42_19285	COG5002	protein histidine kinase activity
G4O42_19290	COG0745	RESPONSE REGULATOR receiver
G4O42_19320	COG0346	lactoylglutathione lyase activity
G4O42_19325	COG0305	Participates in initiation and elongation during chromosome replication
G4O42_19340	COG3093	addiction module antidote protein HigA
G4O42_19345	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G4O42_19350	COG0297	glycogen (starch) synthase activity
G4O42_19360	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G4O42_19365	COG0438	transferase activity, transferring glycosyl groups
G4O42_19385	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
G4O42_19390	COG4241	membrane
G4O42_19400	COG5577	PFAM Coat F domain
G4O42_19405	COG1733	regulation of RNA biosynthetic process
G4O42_19415	COG0697	spore germination
G4O42_19420	COG1621	beta-fructofuranosidase activity
G4O42_19425	COG1621	beta-fructofuranosidase activity
G4O42_19435	COG2318	DinB family
G4O42_19440	COG2211	Major facilitator Superfamily
G4O42_19450	COG0778	Nitroreductase
G4O42_19455	COG1846	Transcriptional regulator
G4O42_19460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G4O42_19465	COG1846	Transcriptional regulator
G4O42_19470	COG2153	protein acetylation
G4O42_19480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G4O42_19485	COG0583	DNA-binding transcription factor activity
G4O42_19490	COG1028	Short-chain dehydrogenase reductase Sdr
G4O42_19495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G4O42_19500	COG0697	spore germination
G4O42_19505	COG1331	Highly conserved protein containing a thioredoxin domain
G4O42_19530	COG1331	Highly conserved protein containing a thioredoxin domain
G4O42_19535	COG1266	CAAX protease self-immunity
G4O42_19540	COG0477	Major facilitator Superfamily
G4O42_19540	COG2814	Major facilitator Superfamily
G4O42_19545	COG0346	lactoylglutathione lyase activity
G4O42_19550	COG1609	Transcriptional regulator
G4O42_19555	COG0708	Exodeoxyribonuclease III
G4O42_19560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G4O42_19565	COG2169	Transcriptional regulator
G4O42_19575	COG0629	single-stranded DNA binding
G4O42_19585	COG0012	GTP binding
G4O42_19590	COG0243	molybdopterin cofactor binding
G4O42_19595	COG4481	Protein conserved in bacteria
G4O42_19600	COG3949	Membrane
G4O42_19615	COG1475	DNA binding
G4O42_19620	COG1192	Involved in chromosome partitioning
G4O42_19645	COG1847	R3H domain protein
G4O42_19650	COG0706	membrane insertase activity