locus-tag	class	description
FLK61_00130	COG3883	PFAM NLP P60 protein
FLK61_00130	COG0791	NLP P60 protein
FLK61_00185	COG0629	single-stranded DNA binding
FLK61_00200	COG0582	viral genome integration into host DNA
FLK61_00230	COG1793	dna ligase
FLK61_00245	COG1525	nuclease
FLK61_00345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLK61_00390	COG0457	Tetratricopeptide repeat
FLK61_00425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLK61_00430	COG0592	DNA-directed DNA polymerase activity
FLK61_00435	COG2501	S4 domain
FLK61_00440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLK61_00450	COG0187	DNA topoisomerase II activity
FLK61_00455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLK61_00490	COG0516	GMP reductase activity
FLK61_00490	COG0517	IMP dehydrogenase activity
FLK61_00495	COG1686	Belongs to the peptidase S11 family
FLK61_00500	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FLK61_00505	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FLK61_00510	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FLK61_00520	COG1428	Deoxynucleoside kinase
FLK61_00525	COG1428	Deoxynucleoside kinase
FLK61_00530	COG1388	LysM domain
FLK61_00530	COG3858	chitin binding
FLK61_00535	COG1335	isochorismatase
FLK61_00540	COG0590	tRNA wobble adenosine to inosine editing
FLK61_00550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLK61_00555	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FLK61_00560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FLK61_00605	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
FLK61_00610	COG3853	Toxic anion resistance protein (TelA)
FLK61_00615	COG1982	Orn Lys Arg decarboxylase major
FLK61_00620	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FLK61_00625	COG3870	Protein conserved in bacteria
FLK61_00630	COG1728	Protein conserved in bacteria
FLK61_00635	COG0470	DNA polymerase III
FLK61_00640	COG1774	PSP1 C-terminal conserved region
FLK61_00645	COG4467	Involved in initiation control of chromosome replication
FLK61_00650	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FLK61_00655	COG2827	Endonuclease containing a URI domain
FLK61_00660	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLK61_00665	COG2002	toxin-antitoxin pair type II binding
FLK61_00670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_00670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_00675	COG0084	hydrolase, TatD family'
FLK61_00680	COG3584	3D domain protein
FLK61_00680	COG3583	domain protein
FLK61_00685	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FLK61_00690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FLK61_00700	COG4466	Protein conserved in bacteria
FLK61_00710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLK61_00715	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLK61_00720	COG0251	oxidation-reduction process
FLK61_00725	COG2088	sporulation resulting in formation of a cellular spore
FLK61_00730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLK61_00735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLK61_00740	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FLK61_00745	COG0193	aminoacyl-tRNA hydrolase activity
FLK61_00755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLK61_00760	COG2002	toxin-antitoxin pair type II binding
FLK61_00765	COG2244	polysaccharide biosynthetic process
FLK61_00770	COG3956	TIGRFAM MazG family protein
FLK61_00775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FLK61_00790	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FLK61_00795	COG1098	S1 RNA binding domain
FLK61_00810	COG2208	phosphoserine phosphatase activity
FLK61_00815	COG2304	oxidoreductase activity
FLK61_00820	COG0515	serine threonine protein kinase
FLK61_00825	COG0037	tRNA processing
FLK61_00835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLK61_00840	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FLK61_00845	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FLK61_00850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLK61_00855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLK61_00860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLK61_00865	COG0512	Glutamine amidotransferase of anthranilate synthase
FLK61_00870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK61_00875	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FLK61_00880	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLK61_00885	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLK61_00890	COG1396	sequence-specific DNA binding
FLK61_00895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLK61_00900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FLK61_00980	COG4463	regulation of RNA biosynthetic process
FLK61_00985	COG3880	PFAM UvrB UvrC protein
FLK61_00990	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FLK61_00995	COG0542	response to heat
FLK61_01000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLK61_01005	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FLK61_01010	COG4956	integral membrane protein (PIN domain superfamily)
FLK61_01015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FLK61_01020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FLK61_01025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLK61_01035	COG1045	serine acetyltransferase
FLK61_01040	COG0215	cysteine-tRNA ligase activity
FLK61_01045	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FLK61_01050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLK61_01055	COG3688	RNA-binding protein containing a PIN domain
FLK61_01060	COG1595	DNA-templated transcription, initiation
FLK61_01065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FLK61_01070	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLK61_01075	COG0250	Participates in transcription elongation, termination and antitermination
FLK61_01080	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FLK61_01085	COG0081	regulation of translation
FLK61_01090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FLK61_01095	COG0222	ribosome binding
FLK61_01100	COG2813	Specifically methylates the guanine in position
FLK61_01105	COG0085	RNA polymerase activity
FLK61_01110	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLK61_01115	COG1358	cellular component organization or biogenesis
FLK61_01120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FLK61_01125	COG0049	tRNA binding
FLK61_01130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLK61_01135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLK61_01140	COG0596	Alpha beta hydrolase
FLK61_01145	COG0051	transcription antitermination factor activity, RNA binding
FLK61_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FLK61_01155	COG0088	Forms part of the polypeptide exit tunnel
FLK61_01160	COG0089	rRNA binding
FLK61_01165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FLK61_01170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLK61_01175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FLK61_01180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLK61_01185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLK61_01190	COG0255	Belongs to the universal ribosomal protein uL29 family
FLK61_01195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FLK61_01200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FLK61_01210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FLK61_01220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FLK61_01225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FLK61_01230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FLK61_01235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FLK61_01240	COG1841	ribosomal large subunit assembly
FLK61_01245	COG0200	Binds to the 23S rRNA
FLK61_01250	COG0201	protein transport
FLK61_01255	COG0563	adenylate kinase activity
FLK61_01260	COG0024	Methionine aminopeptidase
FLK61_01265	COG2163	COG2163 Ribosomal protein L14E L6E L27E
FLK61_01270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FLK61_01275	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FLK61_01280	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FLK61_01285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FLK61_01290	COG0202	RNA polymerase activity
FLK61_01295	COG0203	ribosomal protein L17
FLK61_01300	COG1122	ATPase activity
FLK61_01305	COG1122	ATPase activity
FLK61_01310	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLK61_01315	COG0101	tRNA pseudouridine synthase activity
FLK61_01320	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FLK61_01325	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FLK61_01330	COG2226	methyltransferase
FLK61_01340	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_01345	COG0489	protein tyrosine kinase activity
FLK61_01355	COG2194	sulfuric ester hydrolase activity
FLK61_01360	COG0726	polysaccharide deacetylase
FLK61_01445	COG0659	secondary active sulfate transmembrane transporter activity
FLK61_01450	COG0385	Bile acid
FLK61_01455	COG2819	hydrolase of the alpha beta superfamily
FLK61_01460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_01465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_01470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_01475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_01475	COG2207	Transcriptional regulator
FLK61_01480	COG3876	Protein conserved in bacteria
FLK61_01485	COG1472	Belongs to the glycosyl hydrolase 3 family
FLK61_01490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLK61_01495	COG1263	PTS System
FLK61_01495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_01500	COG1737	Transcriptional regulator
FLK61_01505	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FLK61_01510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_01515	COG1683	Conserved Protein
FLK61_01545	COG1595	DNA-templated transcription, initiation
FLK61_01550	COG5662	AntiSigma factor
FLK61_01555	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLK61_01560	COG4856	YbbR-like protein
FLK61_01565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLK61_01575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLK61_01590	COG2169	Transcriptional regulator
FLK61_01595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLK61_01600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FLK61_01605	COG3002	Belongs to the UPF0753 family
FLK61_01610	COG0288	reversible hydration of carbon dioxide
FLK61_01620	COG5609	conserved protein (DUF2294)
FLK61_01630	COG0642	Histidine kinase
FLK61_01640	COG0515	serine threonine protein kinase
FLK61_01655	COG1113	amino acid transport
FLK61_01670	COG2602	Beta-lactamase
FLK61_01675	COG2124	cytochrome p450
FLK61_01685	COG0531	amino acid
FLK61_01690	COG0584	glycerophosphoryl diester phosphodiesterase
FLK61_01695	COG2271	Major facilitator Superfamily
FLK61_01710	COG1846	Transcriptional regulator
FLK61_01710	COG0456	acetyltransferase
FLK61_01730	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_01735	COG0697	spore germination
FLK61_01740	COG2207	Transcriptional regulator
FLK61_01740	COG1917	Cupin 2, conserved barrel domain protein
FLK61_01765	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FLK61_01770	COG3591	Belongs to the peptidase S1B family
FLK61_01780	COG0596	Alpha beta hydrolase
FLK61_01785	COG1183	phosphatidylcholine synthase activity
FLK61_01790	COG0586	Pfam SNARE associated Golgi protein
FLK61_01795	COG0688	phosphatidylethanolamine metabolic process
FLK61_01805	COG2312	Erythromycin esterase
FLK61_01810	COG2207	Transcriptional regulator
FLK61_01820	COG1301	dicarboxylic acid transport
FLK61_01825	COG1263	PTS System
FLK61_01825	COG2190	(PTS) system
FLK61_01825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_01830	COG0363	glucosamine-6-phosphate deaminase activity
FLK61_01845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK61_01850	COG0833	amino acid
FLK61_01855	COG2040	homocysteine
FLK61_01870	COG2066	Belongs to the glutaminase family
FLK61_01875	COG4191	Histidine kinase
FLK61_01880	COG0784	Response regulator, receiver
FLK61_01890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLK61_01895	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_01900	COG2271	Major facilitator Superfamily
FLK61_01905	COG4948	Mandelate Racemase Muconate Lactonizing
FLK61_01910	COG2186	Transcriptional regulator
FLK61_01915	COG2721	sulfolactate sulfo-lyase activity
FLK61_01920	COG3173	Aminoglycoside phosphotransferase
FLK61_01930	COG0697	spore germination
FLK61_01935	COG0745	RESPONSE REGULATOR receiver
FLK61_01940	COG2205	protein histidine kinase activity
FLK61_01945	COG1131	(ABC) transporter
FLK61_01965	COG3773	Cell wall hydrolase
FLK61_01970	COG2304	oxidoreductase activity
FLK61_01980	COG3540	Alkaline phosphatase
FLK61_01985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLK61_01990	COG0805	protein transport
FLK61_01995	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FLK61_02000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLK61_02005	COG0477	Major facilitator Superfamily
FLK61_02010	COG1309	transcriptional regulator
FLK61_02015	COG0252	asparaginase activity
FLK61_02020	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FLK61_02025	COG1714	RDD family
FLK61_02030	COG3012	SEC-C Motif Domain Protein
FLK61_02030	COG1405	negative regulation of cell septum assembly
FLK61_02040	COG3279	Response regulator of the LytR AlgR family
FLK61_02050	COG1668	transmembrane transport
FLK61_02055	COG0667	Aldo Keto reductase
FLK61_02070	COG1595	DNA-templated transcription, initiation
FLK61_02075	COG1595	DNA-templated transcription, initiation
FLK61_02080	COG1876	peptidase activity
FLK61_02090	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_02095	COG0366	Alpha amylase catalytic
FLK61_02100	COG0803	Belongs to the bacterial solute-binding protein 9 family
FLK61_02105	COG1121	(ABC) transporter
FLK61_02110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK61_02120	COG2310	stress, protein
FLK61_02125	COG2310	stress, protein
FLK61_02130	COG2310	stress, protein
FLK61_02135	COG0861	Integral membrane protein TerC family
FLK61_02145	COG3853	Toxic anion resistance protein (TelA)
FLK61_02155	COG0477	Major facilitator Superfamily
FLK61_02160	COG2814	Major facilitator Superfamily
FLK61_02165	COG0640	Transcriptional regulator
FLK61_02170	COG0517	IMP dehydrogenase activity
FLK61_02170	COG4175	Glycine betaine
FLK61_02175	COG4176	ABC-type proline glycine betaine transport system permease component
FLK61_02180	COG2113	Glycine betaine
FLK61_02185	COG1473	amidohydrolase
FLK61_02190	COG1288	antiporter activity
FLK61_02205	COG0039	L-malate dehydrogenase activity
FLK61_02220	COG3403	YqcI/YcgG family
FLK61_02235	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FLK61_02240	COG1660	Displays ATPase and GTPase activities
FLK61_02250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLK61_02260	COG2226	methyltransferase
FLK61_02265	COG0583	DNA-binding transcription factor activity
FLK61_02270	COG3458	cephalosporin-C deacetylase activity
FLK61_02275	COG3541	Predicted nucleotidyltransferase
FLK61_02280	COG0506	proline dehydrogenase activity
FLK61_02285	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_02290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK61_02295	COG2508	Transcriptional regulator
FLK61_02300	COG3689	TIGRFAM TIGR03943 family protein
FLK61_02305	COG0701	Predicted permease
FLK61_02310	COG2267	carboxylic ester hydrolase activity
FLK61_02315	COG0492	ferredoxin-NADP+ reductase activity
FLK61_02320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FLK61_02320	COG1587	Uroporphyrinogen-III synthase
FLK61_02325	COG2146	nitrite reductase [NAD(P)H] activity
FLK61_02330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLK61_02335	COG0243	molybdopterin cofactor binding
FLK61_02340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLK61_02345	COG2223	nitrite transmembrane transporter activity
FLK61_02355	COG1376	ErfK ybiS ycfS ynhG family protein
FLK61_02370	COG0765	amino acid transport
FLK61_02375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK61_02385	COG1714	RDD family
FLK61_02395	COG1846	Transcriptional regulator
FLK61_02410	COG2723	6-phospho-beta-galactosidase activity
FLK61_02420	COG3209	COG3209 Rhs family protein
FLK61_02430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FLK61_02435	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FLK61_02440	COG1733	regulation of RNA biosynthetic process
FLK61_02445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLK61_02450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLK61_02455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLK61_02460	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FLK61_02465	COG2814	Major facilitator Superfamily
FLK61_02475	COG0697	spore germination
FLK61_02480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_02490	COG2364	Membrane
FLK61_02495	COG1126	abc transporter atp-binding protein
FLK61_02500	COG0765	amino acid transport
FLK61_02505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK61_02510	COG0583	DNA-binding transcription factor activity
FLK61_02515	COG0163	prenyltransferase activity
FLK61_02520	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FLK61_02535	COG0596	Alpha beta hydrolase
FLK61_02540	COG3104	oligopeptide transport
FLK61_02545	COG5434	Belongs to the glycosyl hydrolase 28 family
FLK61_02555	COG0697	spore germination
FLK61_02565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLK61_02570	COG1136	(ABC) transporter
FLK61_02575	COG0577	efflux transmembrane transporter activity
FLK61_02580	COG0745	RESPONSE REGULATOR receiver
FLK61_02585	COG3850	Histidine kinase
FLK61_02585	COG5002	protein histidine kinase activity
FLK61_02590	COG0457	Tetratricopeptide repeat
FLK61_02610	COG0527	aspartate kinase activity
FLK61_02615	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_02620	COG4605	iron ion homeostasis
FLK61_02625	COG4604	ABC transporter, ATP-binding protein
FLK61_02630	COG4607	ABC-type enterochelin transport system periplasmic component
FLK61_02640	COG2814	Major facilitator Superfamily
FLK61_02645	COG1309	transcriptional regulator
FLK61_02650	COG0778	Nitroreductase
FLK61_02655	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FLK61_02660	COG0640	Transcriptional regulator
FLK61_02665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_02670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLK61_02675	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_02680	COG4975	Glucose uptake
FLK61_02685	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_02690	COG4549	nuclear export factor GLE1
FLK61_02695	COG1276	copper resistance
FLK61_02695	COG2372	response to copper ion
FLK61_02700	COG1349	DNA-binding transcription factor activity
FLK61_02710	COG2213	PTS system mannitol-specific
FLK61_02715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_02720	COG0246	Mannitol dehydrogenase
FLK61_02725	COG0473	3-isopropylmalate dehydrogenase activity
FLK61_02730	COG0681	Belongs to the peptidase S26 family
FLK61_02740	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FLK61_02750	COG0561	phosphatase activity
FLK61_02755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FLK61_02760	COG1914	H( )-stimulated, divalent metal cation uptake system
FLK61_02765	COG4336	lyase activity
FLK61_02770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FLK61_02775	COG1984	allophanate hydrolase subunit 2
FLK61_02780	COG1414	Transcriptional regulator
FLK61_02785	COG2755	lipolytic protein G-D-S-L family
FLK61_02795	COG2329	Antibiotic biosynthesis monooxygenase
FLK61_02800	COG0768	penicillin binding
FLK61_02805	COG4989	oxidoreductase activity
FLK61_02810	COG3711	transcriptional antiterminator
FLK61_02815	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_02820	COG2226	methyltransferase
FLK61_02825	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_02830	COG1917	Cupin 2, conserved barrel domain protein
FLK61_02835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_02840	COG3871	stress protein (general stress protein 26)
FLK61_02850	COG2814	Major facilitator Superfamily
FLK61_02855	COG1522	sequence-specific DNA binding
FLK61_02860	COG0551	DNA topoisomerase type I activity
FLK61_02860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLK61_02865	COG0494	nUDIX hydrolase
FLK61_02870	COG0028	Belongs to the TPP enzyme family
FLK61_02900	COG1914	H( )-stimulated, divalent metal cation uptake system
FLK61_02905	COG2261	transglycosylase associated protein
FLK61_02910	COG4876	unkown
FLK61_02915	COG2217	Heavy metal translocating P-type atpase
FLK61_02920	COG3729	General stress protein
FLK61_02925	COG0662	Cupin 2, conserved barrel domain protein
FLK61_02930	COG2329	Antibiotic biosynthesis monooxygenase
FLK61_02935	COG3546	catalase activity
FLK61_02940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FLK61_02945	COG3290	protein histidine kinase activity
FLK61_02950	COG4565	transcriptional regulatory protein
FLK61_02955	COG1301	dicarboxylic acid transport
FLK61_02960	COG0628	permease
FLK61_02965	COG1131	(ABC) transporter
FLK61_02970	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FLK61_02980	COG1960	acyl-CoA dehydrogenase activity
FLK61_02995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLK61_03000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_03005	COG1181	Belongs to the D-alanine--D-alanine ligase family
FLK61_03010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FLK61_03020	COG0513	Belongs to the DEAD box helicase family
FLK61_03025	COG3402	PFAM membrane-flanked domain
FLK61_03030	COG3428	Bacterial PH domain
FLK61_03035	COG0705	Rhomboid family
FLK61_03040	COG0736	holo-[acyl-carrier-protein] synthase activity
FLK61_03045	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FLK61_03050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLK61_03055	COG0864	Transcriptional regulator
FLK61_03060	COG2337	Toxic component of a toxin-antitoxin (TA) module
FLK61_03065	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_03070	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_03075	COG2172	sigma factor antagonist activity
FLK61_03080	COG2208	phosphoserine phosphatase activity
FLK61_03085	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_03090	COG2172	sigma factor antagonist activity
FLK61_03095	COG1191	sigma factor activity
FLK61_03100	COG2208	phosphoserine phosphatase activity
FLK61_03110	COG1673	EVE domain
FLK61_03115	COG1846	Transcriptional regulator
FLK61_03120	COG2183	response to ionizing radiation
FLK61_03130	COG3091	SprT-like family
FLK61_03170	COG0582	viral genome integration into host DNA
FLK61_03175	COG2856	Zn peptidase
FLK61_03180	COG1396	sequence-specific DNA binding
FLK61_03210	COG1674	ftsk spoiiie
FLK61_03215	COG2946	Replication initiation factor
FLK61_03255	COG0433	COG0433 Predicted ATPase
FLK61_03265	COG5644	endopeptidase inhibitor activity
FLK61_03275	COG0741	lytic transglycosylase activity
FLK61_03275	COG0791	NLP P60 protein
FLK61_03290	COG0457	Tetratricopeptide repeat
FLK61_03325	COG0583	DNA-binding transcription factor activity
FLK61_03330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_03340	COG5444	nuclease activity
FLK61_03350	COG1476	TRANSCRIPTIONal
FLK61_03375	COG0693	protein deglycase activity
FLK61_03380	COG1278	Cold shock
FLK61_03385	COG1329	Transcriptional regulator
FLK61_03395	COG0697	spore germination
FLK61_03400	COG1917	Cupin 2, conserved barrel domain protein
FLK61_03400	COG2207	Transcriptional regulator
FLK61_03410	COG3708	Transcriptional regulator
FLK61_03410	COG2207	Transcriptional regulator
FLK61_03415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_03430	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
FLK61_03445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_03450	COG1309	transcriptional regulator
FLK61_03455	COG0697	spore germination
FLK61_03460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_03465	COG2030	dehydratase
FLK61_03470	COG3545	Serine hydrolase
FLK61_03480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_03485	COG0640	Transcriptional regulator
FLK61_03490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLK61_03500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_03505	COG0697	spore germination
FLK61_03510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_03515	COG0076	glutamate decarboxylase activity
FLK61_03520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLK61_03525	COG0640	Transcriptional regulator
FLK61_03530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLK61_03545	COG4585	Histidine kinase
FLK61_03550	COG2197	response regulator
FLK61_03555	COG2409	Drug exporters of the RND superfamily
FLK61_03560	COG0596	Alpha beta hydrolase
FLK61_03565	COG1811	Na channel or pump
FLK61_03570	COG0789	Transcriptional regulator
FLK61_03570	COG4978	Transcriptional regulator
FLK61_03575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLK61_03580	COG0778	Nitroreductase
FLK61_03585	COG0346	lactoylglutathione lyase activity
FLK61_03590	COG2259	Doxx family
FLK61_03595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_03620	COG2323	membrane
FLK61_03625	COG0071	Belongs to the small heat shock protein (HSP20) family
FLK61_03640	COG1309	transcriptional regulator
FLK61_03650	COG0456	acetyltransferase
FLK61_03665	COG1113	amino acid transport
FLK61_03670	COG2318	DinB family
FLK61_03675	COG1846	Transcriptional regulator
FLK61_03680	COG1033	growth of symbiont in host cell
FLK61_03680	COG2409	Drug exporters of the RND superfamily
FLK61_03685	COG0778	Nitroreductase
FLK61_03690	COG1846	Transcriptional regulator
FLK61_03695	COG2814	Major facilitator Superfamily
FLK61_03700	COG0730	response to heat
FLK61_03705	COG1802	Transcriptional regulator
FLK61_03710	COG1388	LysM domain
FLK61_03710	COG3858	chitin binding
FLK61_03715	COG1819	glycosyl
FLK61_03725	COG1785	Belongs to the alkaline phosphatase family
FLK61_03730	COG5646	InterPro IPR014922
FLK61_03740	COG0454	-acetyltransferase
FLK61_03745	COG1078	dGTPase activity
FLK61_03750	COG1388	LysM domain
FLK61_03755	COG2814	Major facilitator Superfamily
FLK61_03760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLK61_03775	COG2723	6-phospho-beta-galactosidase activity
FLK61_03780	COG2188	Transcriptional regulator
FLK61_03785	COG1940	carbohydrate kinase activity
FLK61_03795	COG4124	Belongs to the glycosyl hydrolase 26 family
FLK61_03840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FLK61_03845	COG0802	atpase or kinase
FLK61_03850	COG1214	PFAM Peptidase M22, glycoprotease
FLK61_03855	COG0456	acetyltransferase
FLK61_03860	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FLK61_03870	COG0488	(ABC) transporter
FLK61_03875	COG0315	cyclic pyranopterin monophosphate synthase activity
FLK61_03880	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FLK61_03885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLK61_03890	COG0805	protein transport
FLK61_03905	COG1266	CAAX protease self-immunity
FLK61_03910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FLK61_03915	COG0459	protein refolding
FLK61_03930	COG0457	Tetratricopeptide repeat
FLK61_03935	COG1063	alcohol dehydrogenase
FLK61_03940	COG2211	Major facilitator Superfamily
FLK61_03945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_03955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLK61_03960	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FLK61_03965	COG4260	virion core protein, lumpy skin disease virus
FLK61_03975	COG2814	Major facilitator Superfamily
FLK61_03980	COG1063	alcohol dehydrogenase
FLK61_03985	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FLK61_03990	COG0823	Involved in the tonB-independent uptake of proteins
FLK61_04010	COG2267	carboxylic ester hydrolase activity
FLK61_04020	COG2132	Multicopper oxidase
FLK61_04025	COG1113	amino acid transport
FLK61_04035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLK61_04040	COG0714	Associated with various cellular activities
FLK61_04045	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FLK61_04050	COG1305	Transglutaminase-like
FLK61_04055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FLK61_04055	COG0519	Catalyzes the synthesis of GMP from XMP
FLK61_04065	COG2252	PERMEase
FLK61_04070	COG3064	Membrane
FLK61_04080	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FLK61_04090	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLK61_04095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLK61_04100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLK61_04105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FLK61_04110	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLK61_04115	COG0047	phosphoribosylformylglycinamidine synthase activity
FLK61_04120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLK61_04125	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLK61_04130	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FLK61_04135	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLK61_04140	COG0138	bifunctional purine biosynthesis protein purh
FLK61_04145	COG0151	Belongs to the GarS family
FLK61_04150	COG1522	sequence-specific DNA binding
FLK61_04155	COG0531	amino acid
FLK61_04165	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FLK61_04170	COG1470	cell adhesion involved in biofilm formation
FLK61_04175	COG4496	protein, YerC YecD
FLK61_04180	COG0069	glutamate synthase activity
FLK61_04185	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FLK61_04190	COG0210	DNA helicase
FLK61_04195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FLK61_04200	COG4851	CamS sex pheromone cAM373 precursor
FLK61_04210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLK61_04215	COG1285	pathogenesis
FLK61_04220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK61_04225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLK61_04230	COG0154	amidase activity
FLK61_04235	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLK61_04240	COG1309	transcriptional regulator
FLK61_04245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLK61_04250	COG1597	lipid kinase activity
FLK61_04255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLK61_04290	COG5444	nuclease activity
FLK61_04300	COG0457	Tetratricopeptide repeat
FLK61_04310	COG0217	transcriptional regulatory protein
FLK61_04320	COG1309	transcriptional regulator
FLK61_04335	COG3546	catalase activity
FLK61_04340	COG0454	-acetyltransferase
FLK61_04350	COG5578	integral membrane protein
FLK61_04355	COG2972	Histidine kinase
FLK61_04365	COG1653	transport
FLK61_04370	COG1175	transmembrane transport
FLK61_04375	COG0395	ABC-type sugar transport system, permease component
FLK61_04380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FLK61_04385	COG2207	Transcriptional regulator
FLK61_04390	COG2755	lipolytic protein G-D-S-L family
FLK61_04400	COG5578	integral membrane protein
FLK61_04405	COG3401	FG-GAP repeat protein
FLK61_04410	COG3401	FG-GAP repeat protein
FLK61_04415	COG2755	lipolytic protein G-D-S-L family
FLK61_04430	COG1653	transport
FLK61_04435	COG4209	transmembrane transport
FLK61_04440	COG0395	ABC-type sugar transport system, permease component
FLK61_04445	COG1486	melibiose metabolic process
FLK61_04450	COG2323	membrane
FLK61_04455	COG2329	Antibiotic biosynthesis monooxygenase
FLK61_04460	COG0346	lactoylglutathione lyase activity
FLK61_04475	COG5583	Uncharacterized small protein (DUF2292)
FLK61_04480	COG0670	Belongs to the BI1 family
FLK61_04485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLK61_04500	COG3328	transposase activity
FLK61_04510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FLK61_04510	COG2124	cytochrome p450
FLK61_04515	COG1368	sulfuric ester hydrolase activity
FLK61_04520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FLK61_04525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLK61_04530	COG1442	glycosyl transferase family 8
FLK61_04535	COG1216	Glycosyl transferase, family 2
FLK61_04540	COG1442	glycosyl transferase family 8
FLK61_04545	COG2223	nitrite transmembrane transporter activity
FLK61_04550	COG1011	Hydrolase
FLK61_04555	COG0531	amino acid
FLK61_04560	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_04565	COG0840	transmembrane signaling receptor activity
FLK61_04570	COG0488	(ABC) transporter
FLK61_04580	COG0789	Transcriptional regulator
FLK61_04585	COG2814	Major facilitator Superfamily
FLK61_04605	COG0488	(ABC) transporter
FLK61_04610	COG0513	Belongs to the DEAD box helicase family
FLK61_04620	COG3866	Pectate lyase
FLK61_04625	COG0471	metal ion transport
FLK61_04630	COG3290	protein histidine kinase activity
FLK61_04635	COG4565	transcriptional regulatory protein
FLK61_04640	COG3181	Tripartite tricarboxylate transporter family receptor
FLK61_04645	COG2851	Citrate transporter
FLK61_04650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_04655	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FLK61_04660	COG1254	Belongs to the acylphosphatase family
FLK61_04665	COG2258	MOSC domain
FLK61_04685	COG0024	Methionine aminopeptidase
FLK61_04690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_04690	COG1263	PTS System
FLK61_04695	COG1368	sulfuric ester hydrolase activity
FLK61_04710	COG1115	amino acid carrier protein
FLK61_04725	COG0697	spore germination
FLK61_04730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_04730	COG1263	PTS System
FLK61_04735	COG0366	Alpha amylase catalytic
FLK61_04740	COG2188	Transcriptional regulator
FLK61_04745	COG0778	Nitroreductase
FLK61_04750	COG0737	Belongs to the 5'-nucleotidase family
FLK61_04755	COG0693	protein deglycase activity
FLK61_04765	COG2814	Major facilitator Superfamily
FLK61_04770	COG4840	Belongs to the UPF0435 family
FLK61_04775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLK61_04780	COG4980	gas vesicle protein
FLK61_04785	COG1295	ribonuclease BN
FLK61_04790	COG0477	Major facilitator Superfamily
FLK61_04795	COG0387	Pfam Sodium calcium exchanger
FLK61_04805	COG0668	transmembrane transport
FLK61_04810	COG0535	radical SAM domain protein
FLK61_04820	COG0726	polysaccharide deacetylase
FLK61_04825	COG2084	Dehydrogenase
FLK61_04830	COG0598	Magnesium transport protein CorA
FLK61_04835	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FLK61_04840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLK61_04850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLK61_04855	COG4637	Psort location Cytoplasmic, score
FLK61_04865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLK61_04870	COG0022	dehydrogenase e1 component
FLK61_04875	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_04880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLK61_04885	COG3284	Transcriptional regulator
FLK61_04895	COG1742	UPF0060 membrane protein
FLK61_04920	COG4842	Belongs to the WXG100 family
FLK61_04925	COG1486	melibiose metabolic process
FLK61_04930	COG1737	Transcriptional regulator
FLK61_04935	COG1263	PTS System
FLK61_04935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_04940	COG5434	Belongs to the glycosyl hydrolase 28 family
FLK61_04945	COG1132	(ABC) transporter
FLK61_04950	COG1132	(ABC) transporter
FLK61_04955	COG2259	Doxx family
FLK61_04960	COG2514	catechol 2,3-dioxygenase activity
FLK61_04965	COG1917	Cupin 2, conserved barrel domain protein
FLK61_04965	COG4977	sequence-specific DNA binding
FLK61_04970	COG2814	Major facilitator Superfamily
FLK61_04975	COG1082	Xylose isomerase domain protein TIM barrel
FLK61_04985	COG4585	Histidine kinase
FLK61_04990	COG2197	response regulator
FLK61_04995	COG1131	(ABC) transporter
FLK61_05000	COG1511	domain protein
FLK61_05000	COG0842	Transport permease protein
FLK61_05005	COG0842	Transport permease protein
FLK61_05010	COG1695	Transcriptional regulator
FLK61_05015	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FLK61_05020	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FLK61_05025	COG1309	transcriptional regulator
FLK61_05030	COG2814	Major facilitator Superfamily
FLK61_05035	COG2318	DinB family
FLK61_05045	COG1846	Transcriptional regulator
FLK61_05050	COG0392	lysyltransferase activity
FLK61_05050	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FLK61_05055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_05060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_05065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_05070	COG0384	phenazine biosynthesis protein PhzF
FLK61_05075	COG0778	Nitroreductase
FLK61_05090	COG1090	epimerase
FLK61_05095	COG2137	regulation of response to DNA damage stimulus
FLK61_05105	COG2814	Major facilitator Superfamily
FLK61_05120	COG3103	Sh3 type 3 domain protein
FLK61_05125	COG5658	integral membrane protein
FLK61_05130	COG0596	Alpha beta hydrolase
FLK61_05135	COG0463	Glycosyl transferase, family 2
FLK61_05140	COG4485	Bacterial membrane protein, YfhO
FLK61_05145	COG1988	membrane-bound metal-dependent
FLK61_05150	COG1194	a g-specific adenine glycosylase
FLK61_05160	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_05175	COG3557	Belongs to the UPF0374 family
FLK61_05180	COG1132	(ABC) transporter
FLK61_05185	COG4129	membrane
FLK61_05190	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLK61_05195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLK61_05200	COG0735	belongs to the Fur family
FLK61_05310	COG4326	sporulation control protein
FLK61_05320	COG5577	PFAM Coat F domain
FLK61_05325	COG3340	Belongs to the peptidase S51 family
FLK61_05330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FLK61_05345	COG0753	catalase activity
FLK61_05350	COG1116	anion transmembrane transporter activity
FLK61_05355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLK61_05360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLK61_05365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLK61_05375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLK61_05385	COG1476	TRANSCRIPTIONal
FLK61_05400	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FLK61_05410	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FLK61_05415	COG0789	Transcriptional regulator
FLK61_05420	COG1664	Polymer-forming cytoskeletal
FLK61_05425	COG1664	Polymer-forming cytoskeletal
FLK61_05430	COG2766	serine protein kinase
FLK61_05435	COG2718	Belongs to the UPF0229 family
FLK61_05440	COG1846	Transcriptional regulator
FLK61_05445	COG1566	PFAM secretion protein HlyD family protein
FLK61_05455	COG0655	NAD(P)H dehydrogenase (quinone) activity
FLK61_05475	COG1725	Transcriptional regulator
FLK61_05480	COG1131	(ABC) transporter
FLK61_05485	COG1131	(ABC) transporter
FLK61_05490	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FLK61_05495	COG1278	Cold shock
FLK61_05505	COG1464	Belongs to the NlpA lipoprotein family
FLK61_05510	COG3706	GGDEF domain
FLK61_05515	COG1823	symporter activity
FLK61_05520	COG5444	nuclease activity
FLK61_05545	COG0582	viral genome integration into host DNA
FLK61_05550	COG2946	Replication initiation factor
FLK61_05600	COG5644	endopeptidase inhibitor activity
FLK61_05605	COG0741	lytic transglycosylase activity
FLK61_05605	COG0791	NLP P60 protein
FLK61_05625	COG0457	Tetratricopeptide repeat
FLK61_05650	COG1525	nuclease
FLK61_05650	COG4085	toxin activity
FLK61_05650	COG0737	Belongs to the 5'-nucleotidase family
FLK61_05655	COG3764	Sortase (surface protein transpeptidase)
FLK61_05660	COG0564	pseudouridine synthase activity
FLK61_05670	COG0517	IMP dehydrogenase activity
FLK61_05675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLK61_05680	COG3153	acetyltransferase
FLK61_05680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLK61_05685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLK61_05690	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FLK61_05695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FLK61_05700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLK61_05705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLK61_05710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLK61_05715	COG4585	Histidine kinase
FLK61_05715	COG2203	Gaf domain
FLK61_05720	COG2197	response regulator
FLK61_05725	COG0431	NADPH-dependent FMN reductase
FLK61_05740	COG1388	LysM domain
FLK61_05740	COG0791	NLP P60 protein
FLK61_05745	COG1959	2 iron, 2 sulfur cluster binding
FLK61_05750	COG0668	transmembrane transport
FLK61_05755	COG2719	SpoVR family
FLK61_05760	COG1785	Belongs to the alkaline phosphatase family
FLK61_05765	COG0791	NLP P60 protein
FLK61_05765	COG1388	LysM domain
FLK61_05770	COG0583	DNA-binding transcription factor activity
FLK61_05775	COG0372	Belongs to the citrate synthase family
FLK61_05780	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_05785	COG0531	amino acid
FLK61_05790	COG0733	neurotransmitter:sodium symporter activity
FLK61_05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_05800	COG0456	acetyltransferase
FLK61_05815	COG1595	DNA-templated transcription, initiation
FLK61_05820	COG0667	Aldo Keto reductase
FLK61_05825	COG0204	Acyl-transferase
FLK61_05830	COG1253	flavin adenine dinucleotide binding
FLK61_05835	COG0789	Transcriptional regulator
FLK61_05845	COG1253	flavin adenine dinucleotide binding
FLK61_05850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLK61_05855	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLK61_05860	COG0584	glycerophosphoryl diester phosphodiesterase
FLK61_05870	COG0668	transmembrane transport
FLK61_05875	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FLK61_05880	COG0726	polysaccharide deacetylase
FLK61_05885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK61_05890	COG1757	Na H antiporter
FLK61_05895	COG0589	response to stress
FLK61_05905	COG1132	(ABC) transporter
FLK61_05910	COG1132	(ABC) transporter
FLK61_05915	COG0702	epimerase
FLK61_05940	COG0189	ligase activity
FLK61_05945	COG0189	ligase activity
FLK61_05950	COG4399	Belongs to the UPF0754 family
FLK61_05955	COG3679	Belongs to the UPF0342 family
FLK61_05965	COG0561	phosphatase activity
FLK61_05970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLK61_05975	COG0475	glutathione-regulated potassium exporter activity
FLK61_05980	COG0490	domain, Protein
FLK61_05990	COG1024	Enoyl-CoA hydratase
FLK61_06000	COG4152	abc transporter atp-binding protein
FLK61_06005	COG1668	transmembrane transport
FLK61_06010	COG0420	3'-5' exonuclease activity
FLK61_06015	COG4717	serine-type aminopeptidase activity
FLK61_06020	COG3481	metal-dependent phosphohydrolase, HD sub domain
FLK61_06030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLK61_06060	COG1846	Transcriptional regulator
FLK61_06065	COG4980	gas vesicle protein
FLK61_06080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FLK61_06085	COG0537	adenosine 5'-monophosphoramidase activity
FLK61_06090	COG1131	(ABC) transporter
FLK61_06095	COG4473	ABC transporter
FLK61_06105	COG1473	amidohydrolase
FLK61_06110	COG3069	C4-dicarboxylate transmembrane transporter activity
FLK61_06120	COG2329	Antibiotic biosynthesis monooxygenase
FLK61_06125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_06130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FLK61_06145	COG1309	transcriptional regulator
FLK61_06150	COG1511	domain protein
FLK61_06155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLK61_06160	COG4377	Putative membrane peptidase family (DUF2324)
FLK61_06170	COG1363	Peptidase, m42
FLK61_06175	COG4405	Protein conserved in bacteria
FLK61_06180	COG1301	dicarboxylic acid transport
FLK61_06190	COG1234	tRNA 3'-trailer cleavage
FLK61_06195	COG0095	Lipoate-protein ligase
FLK61_06200	COG0702	epimerase
FLK61_06205	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_06215	COG0501	Belongs to the peptidase M48B family
FLK61_06225	COG0456	acetyltransferase
FLK61_06230	COG0604	alcohol dehydrogenase
FLK61_06235	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FLK61_06240	COG0406	alpha-ribazole phosphatase activity
FLK61_06245	COG0183	Belongs to the thiolase family
FLK61_06250	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_06255	COG1268	BioY protein
FLK61_06260	COG0840	transmembrane signaling receptor activity
FLK61_06270	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_06280	COG4903	ComK protein
FLK61_06285	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_06295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK61_06310	COG0398	Pfam SNARE associated Golgi protein
FLK61_06315	COG0681	Belongs to the peptidase S26 family
FLK61_06320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FLK61_06325	COG1846	Transcriptional regulator
FLK61_06335	COG0738	Major facilitator superfamily
FLK61_06340	COG0673	inositol 2-dehydrogenase activity
FLK61_06345	COG0561	phosphatase activity
FLK61_06350	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLK61_06355	COG1609	Transcriptional regulator
FLK61_06360	COG3180	Ammonia monooxygenase
FLK61_06365	COG2814	Major facilitator Superfamily
FLK61_06365	COG0477	Major facilitator Superfamily
FLK61_06370	COG4533	DNA binding
FLK61_06390	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FLK61_06395	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FLK61_06400	COG1074	ATP-dependent DNA helicase activity
FLK61_06405	COG0420	3'-5' exonuclease activity
FLK61_06410	COG0419	ATPase involved in DNA repair
FLK61_06415	COG1403	HNH endonuclease
FLK61_06455	COG5337	Spore coat protein CotH
FLK61_06460	COG0179	Fumarylacetoacetate (FAA) hydrolase
FLK61_06470	COG1404	Belongs to the peptidase S8 family
FLK61_06480	COG0367	asparagine synthase
FLK61_06485	COG1562	ergosterol biosynthetic process
FLK61_06490	COG0534	Mate efflux family protein
FLK61_06495	COG1917	Cupin 2, conserved barrel domain protein
FLK61_06495	COG2207	Transcriptional regulator
FLK61_06500	COG1609	Transcriptional regulator
FLK61_06505	COG0673	inositol 2-dehydrogenase activity
FLK61_06510	COG2318	DinB family
FLK61_06515	COG1279	arginine transmembrane transporter activity
FLK61_06520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_06525	COG1357	PFAM Pentapeptide repeats (8 copies)
FLK61_06530	COG2267	carboxylic ester hydrolase activity
FLK61_06540	COG2153	protein acetylation
FLK61_06545	COG0646	methionine synthase
FLK61_06545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FLK61_06550	COG1666	GTP binding
FLK61_06555	COG2996	Protein conserved in bacteria
FLK61_06565	COG1307	EDD domain protein, DegV family
FLK61_06570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_06585	COG0561	phosphatase activity
FLK61_06590	COG1073	alpha beta
FLK61_06595	COG2151	metal-sulfur cluster biosynthetic enzyme
FLK61_06615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLK61_06630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLK61_06635	COG0505	Belongs to the CarA family
FLK61_06640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLK61_06645	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FLK61_06665	COG2267	carboxylic ester hydrolase activity
FLK61_06675	COG1744	ABC transporter substrate-binding protein PnrA-like
FLK61_06690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLK61_06695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLK61_06700	COG5504	Zn-dependent protease
FLK61_06705	COG0444	Belongs to the ABC transporter superfamily
FLK61_06710	COG4608	Belongs to the ABC transporter superfamily
FLK61_06720	COG0601	transmembrane transport
FLK61_06725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLK61_06735	COG0180	Tryptophanyl-tRNA synthetase
FLK61_06740	COG4166	transmembrane transport
FLK61_06745	COG0601	transmembrane transport
FLK61_06750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLK61_06755	COG0444	Belongs to the ABC transporter superfamily
FLK61_06760	COG4608	Belongs to the ABC transporter superfamily
FLK61_06765	COG2814	Major facilitator Superfamily
FLK61_06770	COG0456	acetyltransferase
FLK61_06775	COG1393	Belongs to the ArsC family
FLK61_06780	COG0861	Integral membrane protein TerC family
FLK61_06790	COG4862	establishment of competence for transformation
FLK61_06800	COG4469	Competence protein
FLK61_06805	COG1164	Oligoendopeptidase f
FLK61_06825	COG2346	COG2346, Truncated hemoglobins
FLK61_06830	COG0741	lytic transglycosylase activity
FLK61_06835	COG4116	CYTH
FLK61_06845	COG2357	RelA SpoT domain protein
FLK61_06850	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLK61_06855	COG0564	pseudouridine synthase activity
FLK61_06860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FLK61_06865	COG0475	glutathione-regulated potassium exporter activity
FLK61_06865	COG0569	domain protein
FLK61_06870	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FLK61_06875	COG0352	thiamine-phosphate diphosphorylase activity
FLK61_06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLK61_06885	COG2104	thiamine diphosphate biosynthetic process
FLK61_06890	COG2022	thiamine diphosphate biosynthetic process
FLK61_06895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLK61_06900	COG0351	phosphomethylpyrimidine kinase
FLK61_06905	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FLK61_06960	COG0210	DNA helicase
FLK61_06970	COG2153	protein acetylation
FLK61_06975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FLK61_06980	COG2382	esterase
FLK61_06985	COG0626	cystathionine gamma-synthase activity
FLK61_06990	COG0626	cystathionine gamma-synthase activity
FLK61_06995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_07000	COG5505	Protein of unknown function (DUF819)
FLK61_07035	COG1396	sequence-specific DNA binding
FLK61_07100	COG0457	Tetratricopeptide repeat
FLK61_07105	COG5444	nuclease activity
FLK61_07120	COG3328	transposase activity
FLK61_07185	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FLK61_07195	COG3711	transcriptional antiterminator
FLK61_07195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_07200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLK61_07200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_07200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLK61_07205	COG1482	cell wall glycoprotein biosynthetic process
FLK61_07220	COG3328	transposase activity
FLK61_07225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_07235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLK61_07255	COG0109	protoheme IX farnesyltransferase activity
FLK61_07265	COG0726	polysaccharide deacetylase
FLK61_07280	COG5504	Zn-dependent protease
FLK61_07285	COG2205	protein histidine kinase activity
FLK61_07300	COG2427	Protein of unknown function (DUF1641)
FLK61_07310	COG1051	belongs to the nudix hydrolase family
FLK61_07320	COG2124	cytochrome p450
FLK61_07325	COG1819	glycosyl
FLK61_07335	COG1587	Uroporphyrinogen-III synthase
FLK61_07340	COG0390	transport system, permease component
FLK61_07345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLK61_07350	COG0697	spore germination
FLK61_07365	COG1252	NADH dehydrogenase
FLK61_07370	COG1904	glucuronate isomerase
FLK61_07375	COG2211	Major facilitator Superfamily
FLK61_07380	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FLK61_07385	COG1063	alcohol dehydrogenase
FLK61_07390	COG1312	Catalyzes the dehydration of D-mannonate
FLK61_07395	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_07400	COG2271	Major facilitator Superfamily
FLK61_07405	COG1609	Transcriptional regulator
FLK61_07410	COG0246	Mannitol dehydrogenase
FLK61_07415	COG2721	sulfolactate sulfo-lyase activity
FLK61_07420	COG0730	response to heat
FLK61_07425	COG2318	DinB family
FLK61_07445	COG0457	Tetratricopeptide repeat
FLK61_07460	COG1388	LysM domain
FLK61_07460	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLK61_07460	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_07470	COG4195	phage-related replication protein
FLK61_07475	COG3546	catalase activity
FLK61_07480	COG2856	Zn peptidase
FLK61_07485	COG1396	sequence-specific DNA binding
FLK61_07495	COG1522	sequence-specific DNA binding
FLK61_07500	COG1484	DNA-dependent DNA replication
FLK61_07520	COG1595	DNA-templated transcription, initiation
FLK61_07525	COG3728	DNA packaging
FLK61_07525	COG5484	DNA packaging
FLK61_07530	COG1783	phage Terminase large subunit
FLK61_07535	COG5518	Phage portal protein
FLK61_07540	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FLK61_07545	COG4653	Phage capsid family
FLK61_07595	COG5412	phage tail tape measure protein
FLK61_07595	COG5412	phage tail tape measure protein
FLK61_07595	COG3953	SLT domain
FLK61_07595	COG5412	phage tail tape measure protein
FLK61_07595	COG3953	SLT domain
FLK61_07595	COG3953	SLT domain
FLK61_07600	COG1652	LysM domain
FLK61_07605	COG4193	domain, Protein
FLK61_07615	COG3628	GPW Gp25 family protein
FLK61_07620	COG3299	homolog of phage Mu protein gp47
FLK61_07625	COG3778	Protein conserved in bacteria
FLK61_07665	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_07665	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLK61_07685	COG0306	phosphate transporter
FLK61_07690	COG1392	Phosphate transport regulator
FLK61_07695	COG0531	amino acid
FLK61_07700	COG0346	lactoylglutathione lyase activity
FLK61_07705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FLK61_07710	COG0463	Glycosyl transferase, family 2
FLK61_07715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_07720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLK61_07725	COG2362	D-Aminopeptidase
FLK61_07730	COG0601	transmembrane transport
FLK61_07735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLK61_07740	COG0444	Belongs to the ABC transporter superfamily
FLK61_07745	COG4166	transmembrane transport
FLK61_07750	COG1619	proteins homologs of microcin C7 resistance protein MccF
FLK61_07755	COG4948	Mandelate Racemase Muconate Lactonizing
FLK61_07760	COG0791	NLP P60 protein
FLK61_07765	COG4608	Belongs to the ABC transporter superfamily
FLK61_07770	COG2706	6-phosphogluconolactonase activity
FLK61_07780	COG1607	acyl-coa hydrolase
FLK61_07785	COG1017	nitric oxide dioxygenase activity
FLK61_07785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLK61_07795	COG2323	membrane
FLK61_07800	COG2318	DinB family
FLK61_07805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_07810	COG2076	Multidrug Resistance protein
FLK61_07815	COG2076	Multidrug Resistance protein
FLK61_07820	COG0788	formyltetrahydrofolate deformylase activity
FLK61_07825	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLK61_07830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FLK61_07835	COG1764	response to oxidative stress
FLK61_07840	COG1846	Transcriptional regulator
FLK61_07845	COG1764	response to oxidative stress
FLK61_07855	COG0590	tRNA wobble adenosine to inosine editing
FLK61_07860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FLK61_07865	COG1404	Belongs to the peptidase S8 family
FLK61_07870	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_07875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLK61_07880	COG1122	ATPase activity
FLK61_07885	COG4721	ABC-type cobalt transport system, permease component
FLK61_07895	COG0745	RESPONSE REGULATOR receiver
FLK61_07900	COG5002	protein histidine kinase activity
FLK61_07900	COG3850	Histidine kinase
FLK61_07905	COG3212	peptidase
FLK61_07910	COG3212	peptidase
FLK61_07925	COG2239	Acts as a magnesium transporter
FLK61_07930	COG0789	Transcriptional regulator
FLK61_07945	COG1846	Transcriptional regulator
FLK61_07950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLK61_07955	COG0726	polysaccharide deacetylase
FLK61_07960	COG1408	metallophosphoesterase
FLK61_07970	COG0463	Glycosyl transferase, family 2
FLK61_07975	COG3285	dna ligase
FLK61_07975	COG1793	dna ligase
FLK61_07980	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FLK61_07985	COG5001	Diguanylate cyclase
FLK61_07985	COG3300	MHYT domain
FLK61_07990	COG0586	Pfam SNARE associated Golgi protein
FLK61_07995	COG0861	Integral membrane protein TerC family
FLK61_08000	COG1191	sigma factor activity
FLK61_08020	COG0501	Belongs to the peptidase M48B family
FLK61_08025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLK61_08045	COG3594	Acyltransferase
FLK61_08050	COG5002	protein histidine kinase activity
FLK61_08055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLK61_08065	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FLK61_08070	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FLK61_08075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLK61_08080	COG0436	Aminotransferase
FLK61_08085	COG1850	ribulose-bisphosphate carboxylase activity
FLK61_08090	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FLK61_08095	COG0235	Class ii aldolase
FLK61_08100	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FLK61_08105	COG3339	Conserved Protein
FLK61_08120	COG3852	Histidine kinase
FLK61_08125	COG1846	Transcriptional regulator
FLK61_08130	COG1360	Flagellar Motor Protein
FLK61_08135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLK61_08140	COG0542	response to heat
FLK61_08145	COG3949	Membrane
FLK61_08150	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FLK61_08155	COG0720	synthase
FLK61_08160	COG0602	queuosine metabolic process
FLK61_08165	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FLK61_08175	COG4873	Protein conserved in bacteria
FLK61_08185	COG3773	Cell wall hydrolase
FLK61_08190	COG2244	polysaccharide biosynthetic process
FLK61_08195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_08200	COG2217	Heavy metal translocating P-type atpase
FLK61_08210	COG0006	proline dipeptidase activity
FLK61_08215	COG1609	Transcriptional regulator
FLK61_08220	COG3711	transcriptional antiterminator
FLK61_08225	COG2190	(PTS) system
FLK61_08225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_08225	COG1263	PTS System
FLK61_08230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_08235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLK61_08245	COG1533	DNA photolyase activity
FLK61_08250	COG0456	acetyltransferase
FLK61_08255	COG0840	transmembrane signaling receptor activity
FLK61_08260	COG2084	Dehydrogenase
FLK61_08265	COG3328	transposase activity
FLK61_08275	COG2340	Cysteine-rich secretory protein family
FLK61_08280	COG0768	penicillin binding
FLK61_08285	COG4191	Histidine kinase
FLK61_08290	COG0436	Aminotransferase
FLK61_08300	COG0835	chemotaxis
FLK61_08300	COG0784	Response regulator, receiver
FLK61_08310	COG2814	Major facilitator Superfamily
FLK61_08315	COG1376	ErfK ybiS ycfS ynhG family protein
FLK61_08320	COG1408	metallophosphoesterase
FLK61_08325	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_08330	COG2200	EAL domain
FLK61_08335	COG4703	Protein of unknown function (DUF1797)
FLK61_08340	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
FLK61_08350	COG0517	IMP dehydrogenase activity
FLK61_08355	COG0583	DNA-binding transcription factor activity
FLK61_08360	COG0716	FMN binding
FLK61_08370	COG0716	FMN binding
FLK61_08375	COG2171	N-acyltransferase activity
FLK61_08380	COG1473	amidohydrolase
FLK61_08390	COG0668	transmembrane transport
FLK61_08395	COG0450	alkyl hydroperoxide reductase
FLK61_08400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_08420	COG0746	molybdenum cofactor guanylyltransferase activity
FLK61_08425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLK61_08430	COG0303	'Molybdopterin
FLK61_08435	COG1763	Mo-molybdopterin cofactor biosynthetic process
FLK61_08440	COG0314	molybdopterin synthase activity
FLK61_08445	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FLK61_08455	COG1132	(ABC) transporter
FLK61_08465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLK61_08470	COG1136	(ABC) transporter
FLK61_08475	COG0577	efflux transmembrane transporter activity
FLK61_08480	COG1349	DNA-binding transcription factor activity
FLK61_08485	COG1105	Belongs to the carbohydrate kinase PfkB family
FLK61_08490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLK61_08490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLK61_08490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_08495	COG0681	Belongs to the peptidase S26 family
FLK61_08505	COG0488	(ABC) transporter
FLK61_08510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLK61_08515	COG2309	aminopeptidase activity
FLK61_08525	COG1077	Cell shape determining protein MreB Mrl
FLK61_08530	COG2002	toxin-antitoxin pair type II binding
FLK61_08535	COG3852	Histidine kinase
FLK61_08540	COG2105	PFAM AIG2 family protein
FLK61_08540	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FLK61_08545	COG0569	domain protein
FLK61_08550	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FLK61_08555	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLK61_08565	COG0561	phosphatase activity
FLK61_08570	COG0242	peptide deformylase activity
FLK61_08585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLK61_08590	COG0022	dehydrogenase e1 component
FLK61_08595	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_08600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLK61_08605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_08615	COG1982	Orn Lys Arg decarboxylase major
FLK61_08620	COG4476	Belongs to the UPF0223 family
FLK61_08625	COG4493	Belongs to the UPF0637 family
FLK61_08635	COG0483	inositol monophosphate 1-phosphatase activity
FLK61_08650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FLK61_08700	COG4896	Protein conserved in bacteria
FLK61_08710	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FLK61_08715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FLK61_08720	COG2066	Belongs to the glutaminase family
FLK61_08725	COG4838	Belongs to the UPF0358 family
FLK61_08730	COG0772	Belongs to the SEDS family
FLK61_08735	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FLK61_08740	COG1612	heme a metabolic process
FLK61_08745	COG0109	protoheme IX farnesyltransferase activity
FLK61_08750	COG2010	Cytochrome c
FLK61_08750	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FLK61_08755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLK61_08760	COG1845	cytochrome c oxidase, subunit III
FLK61_08765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FLK61_08770	COG3336	cytochrome c oxidase
FLK61_08780	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FLK61_08785	COG2340	Cysteine-rich secretory protein family
FLK61_08800	COG3679	Belongs to the UPF0342 family
FLK61_08805	COG4471	UPF0298 protein
FLK61_08810	COG0742	ribosomal rna small subunit methyltransferase
FLK61_08815	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FLK61_08820	COG3314	Sporulation integral membrane protein YlbJ
FLK61_08825	COG1752	Esterase of the alpha-beta hydrolase superfamily
FLK61_08830	COG3480	Lon protease (S16) C-terminal proteolytic domain
FLK61_08835	COG1323	Belongs to the UPF0348 family
FLK61_08845	COG1399	metal-binding, possibly nucleic acid-binding protein
FLK61_08850	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FLK61_08860	COG0454	-acetyltransferase
FLK61_08865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLK61_08870	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FLK61_08875	COG2001	Belongs to the MraZ family
FLK61_08880	COG0275	rRNA processing
FLK61_08885	COG4839	cell division protein FtsL
FLK61_08895	COG0768	penicillin binding
FLK61_08900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLK61_08905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLK61_08910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLK61_08915	COG0772	Belongs to the SEDS family
FLK61_08920	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLK61_08925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FLK61_08930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FLK61_08935	COG3879	Bacterial protein of unknown function (DUF881)
FLK61_08940	COG3879	Bacterial protein of unknown function (DUF881)
FLK61_08945	COG3856	small basic protein
FLK61_08950	COG0849	cell division
FLK61_08955	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLK61_08960	COG1404	Belongs to the peptidase S8 family
FLK61_08960	COG4412	M6 family metalloprotease domain protein
FLK61_08970	COG1191	sigma factor activity
FLK61_08975	COG1191	sigma factor activity
FLK61_08980	COG1119	ATPase activity
FLK61_08985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLK61_08990	COG1873	PFAM PRC-barrel domain
FLK61_09000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FLK61_09005	COG1799	cell septum assembly
FLK61_09010	COG0762	integral membrane protein
FLK61_09015	COG2302	S4 RNA-binding domain
FLK61_09020	COG3599	regulation of cell shape
FLK61_09025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FLK61_09030	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLK61_09035	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLK61_09040	COG0564	pseudouridine synthase activity
FLK61_09045	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FLK61_09050	COG2233	PERMEase
FLK61_09055	COG0540	Belongs to the ATCase OTCase family
FLK61_09060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLK61_09065	COG0505	Belongs to the CarA family
FLK61_09070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLK61_09075	COG0543	2 iron, 2 sulfur cluster binding
FLK61_09080	COG0167	dihydroorotate dehydrogenase activity
FLK61_09085	COG0284	orotidine-5'-phosphate decarboxylase activity
FLK61_09090	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FLK61_09095	COG0175	sulfate reduction
FLK61_09100	COG0306	phosphate transporter
FLK61_09105	COG2046	Belongs to the sulfate adenylyltransferase family
FLK61_09110	COG0529	Catalyzes the synthesis of activated sulfate
FLK61_09115	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FLK61_09120	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
FLK61_09125	COG1648	precorrin-2 dehydrogenase activity
FLK61_09135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FLK61_09140	COG1561	YicC-like family, N-terminal region
FLK61_09145	COG2052	Domain of unknown function (DUF370)
FLK61_09150	COG0194	GDP metabolic process
FLK61_09155	COG1758	RNA polymerase activity
FLK61_09160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLK61_09165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLK61_09170	COG0242	peptide deformylase activity
FLK61_09175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLK61_09180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLK61_09180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLK61_09185	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FLK61_09190	COG0631	protein serine/threonine phosphatase activity
FLK61_09195	COG2815	serine threonine protein kinase
FLK61_09195	COG0515	serine threonine protein kinase
FLK61_09200	COG1162	GTPase activity
FLK61_09205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLK61_09210	COG1564	THIamine pyrophosphokinase
FLK61_09220	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FLK61_09225	COG1302	Protein conserved in bacteria
FLK61_09230	COG1461	Dihydroxyacetone kinase
FLK61_09235	COG1760	l-serine dehydratase
FLK61_09240	COG1760	l-serine dehydratase
FLK61_09245	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLK61_09250	COG2050	protein possibly involved in aromatic compounds catabolism
FLK61_09250	COG1349	DNA-binding transcription factor activity
FLK61_09255	COG0416	fatty acid biosynthetic process
FLK61_09260	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLK61_09265	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_09270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLK61_09275	COG0571	ribonuclease III activity
FLK61_09280	COG1196	nuclear chromosome segregation
FLK61_09285	COG0552	protein localization to endoplasmic reticulum
FLK61_09295	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FLK61_09300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLK61_09305	COG0228	four-way junction DNA binding
FLK61_09310	COG1837	Belongs to the UPF0109 family
FLK61_09320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FLK61_09325	COG0336	Belongs to the RNA methyltransferase TrmD family
FLK61_09330	COG0335	large ribosomal subunit rRNA binding
FLK61_09335	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FLK61_09340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLK61_09350	COG2257	FlhB HrpN YscU SpaS Family
FLK61_09355	COG0045	succinate-CoA ligase (ADP-forming) activity
FLK61_09360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FLK61_09365	COG0758	DNA mediated transformation
FLK61_09370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLK61_09375	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FLK61_09380	COG4974	Belongs to the 'phage' integrase family
FLK61_09385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FLK61_09390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FLK61_09395	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FLK61_09405	COG1815	bacterial-type flagellum-dependent cell motility
FLK61_09410	COG1558	bacterial-type flagellum-dependent cell motility
FLK61_09415	COG1677	Flagellar hook-basal body complex protein FliE
FLK61_09425	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLK61_09430	COG1317	bacterial-type flagellum organization
FLK61_09435	COG1157	protein secretion by the type III secretion system
FLK61_09440	COG2882	bacterial-type flagellum organization
FLK61_09445	COG3334	PFAM MgtE intracellular
FLK61_09450	COG3144	bacterial-type flagellum assembly
FLK61_09455	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FLK61_09460	COG4786	Flagellar basal body rod
FLK61_09465	COG1582	Flagellar protein (FlbD)
FLK61_09470	COG1580	Controls the rotational direction of flagella during chemotaxis
FLK61_09475	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLK61_09480	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLK61_09480	COG1776	CheC inhibitor of MCP methylation
FLK61_09485	COG2201	protein-glutamate methylesterase activity
FLK61_09490	COG3190	flagellar
FLK61_09495	COG1338	Plays a role in the flagellum-specific transport system
FLK61_09500	COG1987	bacterial-type flagellum assembly
FLK61_09505	COG1684	flagellar biosynthetic protein fliR
FLK61_09510	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLK61_09515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLK61_09520	COG1419	protein localization to endoplasmic reticulum
FLK61_09525	COG0455	bacterial-type flagellum organization
FLK61_09530	COG2201	protein-glutamate methylesterase activity
FLK61_09535	COG0643	Histidine kinase
FLK61_09535	COG2198	Histidine kinase
FLK61_09540	COG0835	chemotaxis
FLK61_09550	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FLK61_09555	COG1191	sigma factor activity
FLK61_09565	COG0052	Belongs to the universal ribosomal protein uS2 family
FLK61_09570	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FLK61_09575	COG0528	UMP kinase activity
FLK61_09580	COG0233	cytoplasmic translational termination
FLK61_09585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLK61_09590	COG4589	Belongs to the CDS family
FLK61_09595	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FLK61_09600	COG0750	zinc metalloprotease
FLK61_09605	COG0442	prolyl-tRNA aminoacylation
FLK61_09610	COG2176	DNA-directed DNA polymerase activity
FLK61_09615	COG0779	Required for maturation of 30S ribosomal subunits
FLK61_09620	COG0195	Participates in both transcription termination and antitermination
FLK61_09625	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FLK61_09630	COG1358	cellular component organization or biogenesis
FLK61_09635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLK61_09640	COG1550	Protein conserved in bacteria
FLK61_09645	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FLK61_09650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLK61_09655	COG0196	riboflavin kinase activity
FLK61_09660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FLK61_09665	COG1185	polyribonucleotide nucleotidyltransferase activity
FLK61_09670	COG0726	polysaccharide deacetylase
FLK61_09675	COG0612	Peptidase, M16
FLK61_09680	COG1873	PFAM PRC-barrel domain
FLK61_09685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLK61_09690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLK61_09695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLK61_09700	COG0527	aspartate kinase activity
FLK61_09705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLK61_09710	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLK61_09715	COG0740	serine-type endopeptidase activity
FLK61_09725	COG4980	gas vesicle protein
FLK61_09725	COG1674	ftsk spoiiie
FLK61_09730	COG2188	Transcriptional regulator
FLK61_09735	COG2814	Major facilitator Superfamily
FLK61_09740	COG0612	Peptidase, M16
FLK61_09745	COG0612	Peptidase, M16
FLK61_09750	COG0300	oxidoreductase activity
FLK61_09765	COG1426	Protein conserved in bacteria
FLK61_09770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLK61_09775	COG1058	Belongs to the CinA family
FLK61_09775	COG1546	Belongs to the CinA family
FLK61_09780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FLK61_09785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FLK61_09790	COG1418	mRNA catabolic process
FLK61_09795	COG1692	metallophosphoesterase
FLK61_09800	COG2359	stage V sporulation protein S
FLK61_09805	COG1063	alcohol dehydrogenase
FLK61_09810	COG0156	8-amino-7-oxononanoate synthase activity
FLK61_09815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLK61_09820	COG4550	Control of competence regulator ComK, YlbF/YmcA
FLK61_09830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FLK61_09835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FLK61_09905	COG3328	transposase activity
FLK61_09925	COG3226	Transcriptional regulator
FLK61_09935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_09940	COG1404	Belongs to the peptidase S8 family
FLK61_09950	COG4195	phage-related replication protein
FLK61_09955	COG1764	response to oxidative stress
FLK61_09960	COG2076	Multidrug Resistance protein
FLK61_09965	COG2076	Multidrug Resistance protein
FLK61_09980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FLK61_09985	COG1923	regulation of RNA biosynthetic process
FLK61_10000	COG1780	Probably involved in ribonucleotide reductase function
FLK61_10005	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLK61_10010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLK61_10015	COG4112	unkown
FLK61_10020	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_10030	COG0464	growth
FLK61_10035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLK61_10040	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FLK61_10045	COG0789	Transcriptional regulator
FLK61_10050	COG0174	glutamine synthetase
FLK61_10055	COG4974	Belongs to the 'phage' integrase family
FLK61_10075	COG3645	SOS response
FLK61_10075	COG3646	Phage regulatory protein
FLK61_10220	COG5412	phage tail tape measure protein
FLK61_10220	COG3953	SLT domain
FLK61_10265	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLK61_10265	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_10265	COG1388	LysM domain
FLK61_10275	COG5444	nuclease activity
FLK61_10315	COG4282	regulation of fungal-type cell wall biogenesis
FLK61_10340	COG3328	transposase activity
FLK61_10355	COG3655	Transcriptional regulator
FLK61_10380	COG0135	phosphoribosylanthranilate isomerase activity
FLK61_10385	COG2211	Major facilitator Superfamily
FLK61_10400	COG3507	Belongs to the glycosyl hydrolase 43 family
FLK61_10405	COG1940	carbohydrate kinase activity
FLK61_10410	COG2115	Belongs to the xylose isomerase family
FLK61_10415	COG1070	Carbohydrate kinase
FLK61_10430	COG3328	transposase activity
FLK61_10435	COG1525	nuclease
FLK61_10440	COG2814	Major facilitator Superfamily
FLK61_10445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLK61_10460	COG0756	dUTP diphosphatase activity
FLK61_10500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLK61_10515	COG3832	glyoxalase III activity
FLK61_10560	COG4195	phage-related replication protein
FLK61_10570	COG0346	lactoylglutathione lyase activity
FLK61_10580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLK61_10585	COG1388	LysM domain
FLK61_10590	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FLK61_10595	COG4224	UPF0291 protein
FLK61_10600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FLK61_10610	COG3763	UPF0154 protein
FLK61_10620	COG0785	Cytochrome C biogenesis protein
FLK61_10625	COG2201	protein-glutamate methylesterase activity
FLK61_10630	COG4846	Membrane protein involved in cytochrome C biogenesis
FLK61_10645	COG0071	Belongs to the small heat shock protein (HSP20) family
FLK61_10660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLK61_10665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_10685	COG0824	Thioesterase
FLK61_10695	COG4841	protein insertion into membrane
FLK61_10700	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FLK61_10705	COG1832	CoA-binding protein
FLK61_10710	COG0187	DNA topoisomerase II activity
FLK61_10715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLK61_10725	COG1115	amino acid carrier protein
FLK61_10730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FLK61_10740	COG5520	Belongs to the glycosyl hydrolase 30 family
FLK61_10750	COG2246	polysaccharide biosynthetic process
FLK61_10755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLK61_10760	COG0586	Pfam SNARE associated Golgi protein
FLK61_10765	COG2404	hydrolase activity, acting on ester bonds
FLK61_10770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FLK61_10775	COG1024	Enoyl-CoA hydratase
FLK61_10780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLK61_10785	COG0511	ligase activity, forming carbon-carbon bonds
FLK61_10790	COG0439	Biotin carboxylase
FLK61_10795	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_10800	COG1960	acyl-CoA dehydrogenase activity
FLK61_10810	COG1649	PFAM Uncharacterised BCR, COG1649
FLK61_10825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLK61_10830	COG2027	D-alanyl-D-alanine carboxypeptidase
FLK61_10835	COG2017	converts alpha-aldose to the beta-anomer
FLK61_10840	COG0534	Mate efflux family protein
FLK61_10860	COG0582	viral genome integration into host DNA
FLK61_10865	COG0166	Belongs to the GPI family
FLK61_10870	COG0405	Gamma-glutamyltransferase
FLK61_10875	COG0583	DNA-binding transcription factor activity
FLK61_10880	COG0604	alcohol dehydrogenase
FLK61_10885	COG0493	'glutamate synthase
FLK61_10890	COG0070	glutamate synthase
FLK61_10890	COG0069	glutamate synthase activity
FLK61_10890	COG0067	glutamate synthase
FLK61_10895	COG0583	DNA-binding transcription factor activity
FLK61_10925	COG0300	oxidoreductase activity
FLK61_10930	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FLK61_10940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_10955	COG1131	(ABC) transporter
FLK61_10965	COG2814	Major facilitator Superfamily
FLK61_10975	COG3328	transposase activity
FLK61_11010	COG3328	transposase activity
FLK61_11070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLK61_11075	COG2226	methyltransferase
FLK61_11080	COG2211	Major facilitator Superfamily
FLK61_11085	COG3328	transposase activity
FLK61_11115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_11135	COG5444	nuclease activity
FLK61_11140	COG4282	regulation of fungal-type cell wall biogenesis
FLK61_11145	COG1231	oxidoreductase activity
FLK61_11150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_11155	COG2207	Transcriptional regulator
FLK61_11155	COG0662	Cupin 2, conserved barrel domain protein
FLK61_11160	COG0456	acetyltransferase
FLK61_11165	COG1309	transcriptional regulator
FLK61_11170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_11175	COG3708	Transcriptional regulator
FLK61_11180	COG2378	regulation of single-species biofilm formation
FLK61_11190	COG0640	Transcriptional regulator
FLK61_11195	COG0741	lytic transglycosylase activity
FLK61_11200	COG2322	membrane
FLK61_11215	COG1619	proteins homologs of microcin C7 resistance protein MccF
FLK61_11220	COG3239	Fatty acid desaturase
FLK61_11225	COG4585	Histidine kinase
FLK61_11230	COG2197	response regulator
FLK61_11235	COG1388	LysM domain
FLK61_11235	COG3584	3D domain protein
FLK61_11240	COG0514	ATP-dependent DNA helicase (RecQ)
FLK61_11255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLK61_11260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLK61_11275	COG0071	Belongs to the small heat shock protein (HSP20) family
FLK61_11300	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_11305	COG1657	PFAM Prenyltransferase squalene oxidase
FLK61_11310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLK61_11315	COG0733	neurotransmitter:sodium symporter activity
FLK61_11320	COG0385	Bile acid
FLK61_11325	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_11330	COG0567	Dehydrogenase, E1 component
FLK61_11335	COG4548	von Willebrand factor, type A
FLK61_11340	COG0714	Associated with various cellular activities
FLK61_11345	COG2032	superoxide dismutase activity
FLK61_11350	COG1388	LysM domain
FLK61_11350	COG0791	NLP P60 protein
FLK61_11355	COG1819	glycosyl
FLK61_11360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLK61_11365	COG0534	Mate efflux family protein
FLK61_11370	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_11375	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLK61_11380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLK61_11390	COG2962	Rard protein
FLK61_11410	COG1942	4-Oxalocrotonate Tautomerase
FLK61_11415	COG1733	regulation of RNA biosynthetic process
FLK61_11420	COG0778	Nitroreductase
FLK61_11430	COG0400	carboxylic ester hydrolase activity
FLK61_11445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK61_11450	COG0793	Belongs to the peptidase S41A family
FLK61_11450	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_11455	COG2226	methyltransferase
FLK61_11465	COG1876	peptidase activity
FLK61_11470	COG0813	purine-nucleoside phosphorylase activity
FLK61_11485	COG0671	phosphoesterase, PA-phosphatase related
FLK61_11510	COG4479	Belongs to the UPF0346 family
FLK61_11520	COG1509	lysine 2,3-aminomutase activity
FLK61_11525	COG0456	acetyltransferase
FLK61_11530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLK61_11535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FLK61_11540	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLK61_11545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLK61_11560	COG0456	acetyltransferase
FLK61_11565	COG0463	Glycosyl transferase, family 2
FLK61_11580	COG4641	Protein conserved in bacteria
FLK61_11585	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
FLK61_11590	COG1086	Polysaccharide biosynthesis protein
FLK61_11595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_11600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_11605	COG1846	Transcriptional regulator
FLK61_11610	COG0534	Mate efflux family protein
FLK61_11620	COG4698	Protein conserved in bacteria
FLK61_11625	COG2755	lipolytic protein G-D-S-L family
FLK61_11630	COG1999	signal sequence binding
FLK61_11640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLK61_11645	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FLK61_11650	COG1272	protein, Hemolysin III
FLK61_11655	COG0204	Acyl-transferase
FLK61_11660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLK61_11665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FLK61_11675	COG2521	methyltransferase
FLK61_11675	COG2136	Putative SAM-dependent methyltransferase
FLK61_11685	COG0129	dihydroxy-acid dehydratase activity
FLK61_11690	COG1413	lyase activity
FLK61_11695	COG1418	mRNA catabolic process
FLK61_11700	COG0386	Belongs to the glutathione peroxidase family
FLK61_11705	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FLK61_11710	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLK61_11720	COG1278	Cold shock
FLK61_11740	COG0328	RNA-DNA hybrid ribonuclease activity
FLK61_11745	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FLK61_11750	COG0328	RNA-DNA hybrid ribonuclease activity
FLK61_11760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK61_11775	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FLK61_11785	COG1755	Isoprenylcysteine carboxyl methyltransferase
FLK61_11790	COG3424	synthase
FLK61_11795	COG2233	PERMEase
FLK61_11800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLK61_11805	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FLK61_11815	COG0800	Aldolase
FLK61_11820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_11825	COG1609	Transcriptional regulator
FLK61_11830	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FLK61_11835	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_11840	COG1199	ATP-dependent helicase activity
FLK61_11855	COG0116	Belongs to the methyltransferase superfamily
FLK61_11870	COG4474	Belongs to the UPF0398 family
FLK61_11885	COG3359	exonuclease
FLK61_11890	COG1205	dead DEAH box helicase
FLK61_11890	COG1111	helicase
FLK61_11895	COG2190	(PTS) system
FLK61_11900	COG0071	Belongs to the small heat shock protein (HSP20) family
FLK61_11935	COG3331	DNA recombination
FLK61_11940	COG4499	WXG100 protein secretion system (Wss), protein YukC
FLK61_11940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_11950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLK61_11955	COG3935	DnaD domain protein
FLK61_11960	COG0017	Asparaginyl-tRNA synthetase
FLK61_11965	COG0436	Aminotransferase
FLK61_11970	COG5353	protein conserved in bacteria
FLK61_11980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FLK61_11980	COG1199	ATP-dependent helicase activity
FLK61_11985	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FLK61_11990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FLK61_11995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FLK61_12000	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FLK61_12000	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FLK61_12005	COG0617	tRNA 3'-terminal CCA addition
FLK61_12010	COG0438	transferase activity, transferring glycosyl groups
FLK61_12015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLK61_12020	COG1803	Methylglyoxal synthase
FLK61_12025	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FLK61_12030	COG1694	Mazg nucleotide pyrophosphohydrolase
FLK61_12035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_12045	COG4347	Protein of unknown function (DUF1405)
FLK61_12050	COG2010	Cytochrome c
FLK61_12050	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLK61_12055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLK61_12060	COG0723	plastoquinol--plastocyanin reductase activity
FLK61_12070	COG5582	Belongs to the UPF0302 family
FLK61_12075	COG0457	Tetratricopeptide repeat
FLK61_12080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FLK61_12085	COG0287	Prephenate dehydrogenase
FLK61_12100	COG0133	tryptophan synthase activity
FLK61_12105	COG0135	phosphoribosylanthranilate isomerase activity
FLK61_12115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLK61_12120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLK61_12125	COG4401	Chorismate mutase type I
FLK61_12130	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FLK61_12135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FLK61_12140	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FLK61_12145	COG0105	UTP biosynthetic process
FLK61_12150	COG0142	geranyltranstransferase activity
FLK61_12155	COG2226	methyltransferase
FLK61_12160	COG0142	geranyltranstransferase activity
FLK61_12170	COG0302	gtp cyclohydrolase
FLK61_12175	COG0776	regulation of translation
FLK61_12180	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FLK61_12195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FLK61_12200	COG1160	GTP binding
FLK61_12225	COG1304	FMN binding
FLK61_12230	COG0539	negative regulation of cytoplasmic translation
FLK61_12235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FLK61_12245	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FLK61_12250	COG2959	enzyme of heme biosynthesis
FLK61_12255	COG3773	Cell wall hydrolase
FLK61_12255	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_12260	COG2339	peptidase activity
FLK61_12265	COG0492	ferredoxin-NADP+ reductase activity
FLK61_12270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLK61_12275	COG4862	establishment of competence for transformation
FLK61_12280	COG1408	metallophosphoesterase
FLK61_12290	COG1388	LysM domain
FLK61_12295	COG1266	CAAX protease self-immunity
FLK61_12300	COG0514	ATP-dependent DNA helicase (RecQ)
FLK61_12305	COG4955	Helix-turn-helix domain
FLK61_12310	COG1141	Ferredoxin
FLK61_12315	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FLK61_12320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLK61_12325	COG0710	3-dehydroquinate dehydratase activity
FLK61_12335	COG1595	DNA-templated transcription, initiation
FLK61_12340	COG5002	protein histidine kinase activity
FLK61_12345	COG0745	RESPONSE REGULATOR receiver
FLK61_12350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLK61_12355	COG1333	cytochrome c biogenesis protein
FLK61_12360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_12365	COG1187	pseudouridine synthase activity
FLK61_12370	COG0700	Nucleoside recognition
FLK61_12375	COG2715	membrane protein required for spore maturation
FLK61_12380	COG1686	Belongs to the peptidase S11 family
FLK61_12390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLK61_12395	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FLK61_12400	COG1547	Domain of unknown function (DUF309)
FLK61_12405	COG0456	acetyltransferase
FLK61_12410	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FLK61_12415	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLK61_12415	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLK61_12420	COG0307	riboflavin synthase, alpha
FLK61_12425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLK61_12425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLK61_12435	COG0681	Belongs to the peptidase S26 family
FLK61_12445	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
FLK61_12495	COG3328	transposase activity
FLK61_12550	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLK61_12565	COG4086	secreted protein
FLK61_12570	COG0019	diaminopimelate decarboxylase activity
FLK61_12575	COG0697	spore germination
FLK61_12590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLK61_12610	COG1191	sigma factor activity
FLK61_12615	COG2172	sigma factor antagonist activity
FLK61_12620	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_12625	COG1686	Belongs to the peptidase S11 family
FLK61_12630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FLK61_12635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FLK61_12640	COG4974	Belongs to the 'phage' integrase family
FLK61_12650	COG0735	belongs to the Fur family
FLK61_12655	COG1300	Membrane
FLK61_12665	COG0281	malic enzyme
FLK61_12670	COG1757	Na H antiporter
FLK61_12675	COG1027	Aspartate ammonia-lyase
FLK61_12680	COG0252	asparaginase activity
FLK61_12685	COG1396	sequence-specific DNA binding
FLK61_12690	COG1379	DNA repair
FLK61_12695	COG0494	nUDIX hydrolase
FLK61_12705	COG0667	Aldo Keto reductase
FLK61_12715	COG1073	alpha beta
FLK61_12725	COG4918	Iron-sulphur cluster biosynthesis
FLK61_12730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLK61_12730	COG0456	acetyltransferase
FLK61_12735	COG2329	Antibiotic biosynthesis monooxygenase
FLK61_12740	COG0456	acetyltransferase
FLK61_12750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLK61_12760	COG2211	Major facilitator Superfamily
FLK61_12765	COG0346	lactoylglutathione lyase activity
FLK61_12770	COG1072	(Pantothenic acid kinase))
FLK61_12775	COG3048	D-serine ammonia-lyase activity
FLK61_12780	COG0300	oxidoreductase activity
FLK61_12785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_12790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLK61_12795	COG4187	Peptidase family M20/M25/M40
FLK61_12800	COG1902	pentaerythritol trinitrate reductase activity
FLK61_12815	COG0596	Alpha beta hydrolase
FLK61_12825	COG1234	tRNA 3'-trailer cleavage
FLK61_12830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLK61_12835	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLK61_12840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLK61_12850	COG0706	membrane insertase activity
FLK61_12855	COG3361	conserved protein (COG2071)
FLK61_12860	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLK61_12870	COG0346	lactoylglutathione lyase activity
FLK61_12875	COG1376	ErfK ybiS ycfS ynhG family protein
FLK61_12880	COG4129	membrane
FLK61_12885	COG1126	abc transporter atp-binding protein
FLK61_12890	COG0765	amino acid transport
FLK61_12895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK61_12905	COG1597	lipid kinase activity
FLK61_12915	COG0789	Transcriptional regulator
FLK61_12915	COG4978	Transcriptional regulator
FLK61_12920	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_12925	COG0022	dehydrogenase e1 component
FLK61_12930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLK61_12935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLK61_12940	COG3426	butyrate kinase activity
FLK61_12945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLK61_12950	COG0280	phosphate acetyltransferase
FLK61_12955	COG3290	protein histidine kinase activity
FLK61_12955	COG3829	transcription factor binding
FLK61_12965	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FLK61_12970	COG2079	MmgE PrpD family protein
FLK61_12975	COG0372	Belongs to the citrate synthase family
FLK61_12980	COG1960	acyl-CoA dehydrogenase activity
FLK61_12985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLK61_12990	COG0183	Belongs to the thiolase family
FLK61_12995	COG0584	glycerophosphoryl diester phosphodiesterase
FLK61_13000	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_13015	COG1902	pentaerythritol trinitrate reductase activity
FLK61_13020	COG0745	RESPONSE REGULATOR receiver
FLK61_13030	COG0750	zinc metalloprotease
FLK61_13035	COG0497	DNA recombination
FLK61_13040	COG1438	arginine binding
FLK61_13045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FLK61_13050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLK61_13055	COG0142	geranyltranstransferase activity
FLK61_13060	COG1722	exodeoxyribonuclease VII activity
FLK61_13065	COG1570	exodeoxyribonuclease VII activity
FLK61_13070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FLK61_13075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLK61_13080	COG1302	Protein conserved in bacteria
FLK61_13085	COG0439	Biotin carboxylase
FLK61_13090	COG0511	ligase activity, forming carbon-carbon bonds
FLK61_13135	COG3854	ATPases associated with a variety of cellular activities
FLK61_13145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FLK61_13150	COG0006	proline dipeptidase activity
FLK61_13155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FLK61_13165	COG3872	metal-dependent enzyme
FLK61_13175	COG1752	Esterase of the alpha-beta hydrolase superfamily
FLK61_13180	COG1321	iron dependent repressor
FLK61_13185	COG0095	Lipoate-protein ligase
FLK61_13190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK61_13195	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLK61_13200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLK61_13205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLK61_13210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLK61_13225	COG1396	sequence-specific DNA binding
FLK61_13235	COG0681	Belongs to the peptidase S26 family
FLK61_13260	COG4940	Competence protein ComGF
FLK61_13270	COG4970	Tfp pilus assembly protein FimT
FLK61_13275	COG4537	Required for transformation and DNA binding
FLK61_13280	COG1459	type II secretion system
FLK61_13285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLK61_13290	COG0517	IMP dehydrogenase activity
FLK61_13295	COG0598	Magnesium transport protein CorA
FLK61_13300	COG1253	flavin adenine dinucleotide binding
FLK61_13305	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_13315	COG1393	Belongs to the ArsC family
FLK61_13325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_13335	COG0011	TIGRFAM Protein of
FLK61_13345	COG2866	Carboxypeptidase
FLK61_13350	COG1368	sulfuric ester hydrolase activity
FLK61_13355	COG1940	carbohydrate kinase activity
FLK61_13360	COG4483	Protein conserved in bacteria
FLK61_13365	COG0457	Tetratricopeptide repeat
FLK61_13365	COG0705	Rhomboid family
FLK61_13375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLK61_13380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FLK61_13385	COG0438	transferase activity, transferring glycosyl groups
FLK61_13400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLK61_13405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLK61_13410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLK61_13415	COG0581	inorganic phosphate transmembrane transporter activity
FLK61_13420	COG0573	inorganic phosphate transmembrane transporter activity
FLK61_13425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FLK61_13435	COG0477	Major facilitator Superfamily
FLK61_13440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLK61_13445	COG2839	Protein conserved in bacteria
FLK61_13450	COG5521	maltodextrose utilization protein MalA
FLK61_13455	COG1388	LysM domain
FLK61_13460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FLK61_13465	COG4709	membrane
FLK61_13470	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FLK61_13475	COG0735	belongs to the Fur family
FLK61_13480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_13490	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FLK61_13495	COG0513	Belongs to the DEAD box helicase family
FLK61_13505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FLK61_13510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLK61_13515	COG2384	SAM-dependent methyltransferase
FLK61_13520	COG2010	Cytochrome c
FLK61_13530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLK61_13535	COG0358	DNA primase activity
FLK61_13540	COG1671	Belongs to the UPF0178 family
FLK61_13545	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FLK61_13550	COG0517	IMP dehydrogenase activity
FLK61_13555	COG0751	glycine-tRNA ligase activity
FLK61_13560	COG0752	glycyl-tRNA synthetase alpha subunit
FLK61_13565	COG1381	Involved in DNA repair and RecF pathway recombination
FLK61_13575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FLK61_13580	COG0295	cytidine deaminase activity
FLK61_13585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FLK61_13590	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FLK61_13595	COG1480	7TM receptor with intracellular HD hydrolase
FLK61_13600	COG1702	phosphate starvation-inducible protein PhoH
FLK61_13605	COG0561	phosphatase activity
FLK61_13620	COG4864	UPF0365 protein
FLK61_13625	COG1030	water channel activity
FLK61_13630	COG1610	YqeY-like protein
FLK61_13635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FLK61_13640	COG1283	sodium-dependent phosphate transmembrane transporter activity
FLK61_13645	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLK61_13650	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FLK61_13655	COG2264	protein methyltransferase activity
FLK61_13660	COG0484	heat shock protein binding
FLK61_13665	COG0443	Heat shock 70 kDa protein
FLK61_13670	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FLK61_13675	COG1420	regulation of RNA biosynthetic process
FLK61_13680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLK61_13685	COG0481	GTPase activity
FLK61_13695	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_13700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FLK61_13705	COG0268	Binds directly to 16S ribosomal RNA
FLK61_13710	COG1466	dna polymerase III delta subunit
FLK61_13725	COG0658	competence protein
FLK61_13725	COG2333	competence protein COMEC
FLK61_13730	COG2131	deaminase
FLK61_13735	COG1596	polysaccharide export
FLK61_13735	COG1555	photosystem II stabilization
FLK61_13740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLK61_13745	COG2226	methyltransferase
FLK61_13750	COG0799	negative regulation of ribosome biogenesis
FLK61_13755	COG1713	HD superfamily hydrolase involved in NAD metabolism
FLK61_13760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLK61_13765	COG1534	Rna-binding protein
FLK61_13770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLK61_13775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FLK61_13780	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FLK61_13790	COG2755	lipolytic protein G-D-S-L family
FLK61_13795	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLK61_13795	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_13800	COG0398	Pfam SNARE associated Golgi protein
FLK61_13805	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FLK61_13815	COG3209	COG3209 Rhs family protein
FLK61_13835	COG0114	fumarate hydratase activity
FLK61_13840	COG0583	DNA-binding transcription factor activity
FLK61_13855	COG0457	Tetratricopeptide repeat
FLK61_13990	COG0789	Transcriptional regulator
FLK61_13990	COG4978	Transcriptional regulator
FLK61_13995	COG2814	Major facilitator Superfamily
FLK61_14000	COG0456	acetyltransferase
FLK61_14005	COG1253	flavin adenine dinucleotide binding
FLK61_14015	COG0697	spore germination
FLK61_14020	COG0583	DNA-binding transcription factor activity
FLK61_14025	COG2072	flavoprotein involved in K transport
FLK61_14030	COG1230	cation diffusion facilitator family transporter
FLK61_14040	COG1114	Component of the transport system for branched-chain amino acids
FLK61_14045	COG1687	branched-chain amino acid
FLK61_14055	COG1522	sequence-specific DNA binding
FLK61_14060	COG2732	(Barnase) inhibitor
FLK61_14065	COG2124	cytochrome p450
FLK61_14075	COG1335	isochorismatase
FLK61_14090	COG2318	DinB family
FLK61_14100	COG2070	2-Nitropropane dioxygenase
FLK61_14115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FLK61_14135	COG3443	Belongs to the bacterial solute-binding protein 9 family
FLK61_14140	COG1595	DNA-templated transcription, initiation
FLK61_14145	COG0667	Aldo Keto reductase
FLK61_14150	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_14155	COG5566	PFAM Mor transcription activator
FLK61_14165	COG4991	sh3 domain protein
FLK61_14170	COG4991	sh3 domain protein
FLK61_14180	COG0346	lactoylglutathione lyase activity
FLK61_14190	COG5577	PFAM Coat F domain
FLK61_14195	COG1063	alcohol dehydrogenase
FLK61_14205	COG5577	PFAM Coat F domain
FLK61_14210	COG0789	Transcriptional regulator
FLK61_14220	COG1064	alcohol dehydrogenase
FLK61_14225	COG0693	protein deglycase activity
FLK61_14230	COG1621	beta-fructofuranosidase activity
FLK61_14235	COG3716	PTS system mannose fructose sorbose family IID component
FLK61_14240	COG3715	PTS system
FLK61_14245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_14250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_14255	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FLK61_14255	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FLK61_14265	COG1113	amino acid transport
FLK61_14270	COG1280	lysine exporter protein (LysE YggA)
FLK61_14275	COG1378	Sugar-specific transcriptional regulator TrmB
FLK61_14280	COG1595	DNA-templated transcription, initiation
FLK61_14305	COG1309	transcriptional regulator
FLK61_14310	COG2226	methyltransferase
FLK61_14325	COG2116	formate transmembrane transporter activity
FLK61_14330	COG5609	conserved protein (DUF2294)
FLK61_14335	COG3383	formate dehydrogenase (NAD+) activity
FLK61_14340	COG2427	Protein of unknown function (DUF1641)
FLK61_14355	COG0626	cystathionine gamma-synthase activity
FLK61_14360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLK61_14365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLK61_14370	COG2226	methyltransferase
FLK61_14385	COG0768	penicillin binding
FLK61_14390	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLK61_14395	COG0572	uridine kinase
FLK61_14415	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLK61_14420	COG3906	Belongs to the UPF0473 family
FLK61_14425	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FLK61_14430	COG4472	Bacterial protein of unknown function (DUF965)
FLK61_14435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLK61_14440	COG0628	permease
FLK61_14445	COG1126	abc transporter atp-binding protein
FLK61_14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK61_14455	COG0765	amino acid transport
FLK61_14460	COG0765	amino acid transport
FLK61_14475	COG3881	PFAM PRC-barrel domain
FLK61_14480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLK61_14485	COG0457	Tetratricopeptide repeat
FLK61_14490	COG0482	sulfurtransferase activity
FLK61_14495	COG1104	cysteine desulfurase activity
FLK61_14500	COG1959	2 iron, 2 sulfur cluster binding
FLK61_14505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FLK61_14510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FLK61_14520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FLK61_14525	COG0124	histidyl-tRNA synthetase
FLK61_14535	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_14535	COG3103	Sh3 type 3 domain protein
FLK61_14535	COG4991	sh3 domain protein
FLK61_14540	COG1490	D-aminoacyl-tRNA deacylase activity
FLK61_14545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLK61_14550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLK61_14555	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FLK61_14555	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FLK61_14560	COG5416	Lipopolysaccharide assembly protein A domain
FLK61_14565	COG0490	domain, Protein
FLK61_14570	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK61_14570	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK61_14580	COG2244	polysaccharide biosynthetic process
FLK61_14585	COG2323	membrane
FLK61_14595	COG1862	Preprotein translocase
FLK61_14600	COG0343	queuine tRNA-ribosyltransferase activity
FLK61_14605	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FLK61_14615	COG2255	four-way junction helicase activity
FLK61_14620	COG0632	four-way junction helicase activity
FLK61_14630	COG2814	Major facilitator Superfamily
FLK61_14640	COG2112	serine threonine protein kinase
FLK61_14660	COG1115	amino acid carrier protein
FLK61_14665	COG0217	transcriptional regulatory protein
FLK61_14675	COG1388	LysM domain
FLK61_14680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FLK61_14685	COG0157	Belongs to the NadC ModD family
FLK61_14690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FLK61_14695	COG1104	cysteine desulfurase activity
FLK61_14700	COG1827	regulation of RNA biosynthetic process
FLK61_14705	COG0077	Prephenate dehydratase
FLK61_14710	COG4492	Belongs to the UPF0735 family
FLK61_14715	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FLK61_14720	COG3290	protein histidine kinase activity
FLK61_14730	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FLK61_14735	COG2868	ribosomal protein
FLK61_14740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FLK61_14745	COG1994	Peptidase M50
FLK61_14750	COG0739	heme binding
FLK61_14755	COG2894	cell division
FLK61_14760	COG0850	regulation of cytokinetic process
FLK61_14765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FLK61_14770	COG1792	Involved in formation and maintenance of cell shape
FLK61_14775	COG1077	Cell shape determining protein MreB Mrl
FLK61_14780	COG2003	Belongs to the UPF0758 family
FLK61_14785	COG0424	maF-like protein
FLK61_14795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FLK61_14800	COG0285	dihydrofolate synthase activity
FLK61_14805	COG0525	valine-tRNA ligase activity
FLK61_14815	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLK61_14820	COG1388	LysM domain
FLK61_14825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLK61_14830	COG0113	porphobilinogen synthase activity
FLK61_14835	COG1587	Uroporphyrinogen-III synthase
FLK61_14840	COG0181	hydroxymethylbilane synthase activity
FLK61_14845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLK61_14850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FLK61_14860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FLK61_14865	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FLK61_14870	COG1067	ATP-dependent peptidase activity
FLK61_14870	COG0470	DNA polymerase III
FLK61_14875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLK61_14880	COG0544	peptidyl-prolyl cis-trans isomerase activity
FLK61_14885	COG1477	protein flavinylation
FLK61_14885	COG0457	Tetratricopeptide repeat
FLK61_14890	COG0066	3-isopropylmalate dehydratase activity
FLK61_14895	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FLK61_14900	COG0473	3-isopropylmalate dehydrogenase activity
FLK61_14905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLK61_14910	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FLK61_14915	COG0440	acetolactate synthase activity
FLK61_14920	COG0028	Belongs to the TPP enzyme family
FLK61_14935	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
FLK61_14965	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FLK61_14990	COG0622	Phosphoesterase
FLK61_14995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLK61_15000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FLK61_15005	COG5401	PFAM Sporulation and spore germination
FLK61_15010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FLK61_15015	COG1846	Transcriptional regulator
FLK61_15020	COG2197	response regulator
FLK61_15025	COG0824	Thioesterase
FLK61_15030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FLK61_15035	COG1053	succinate dehydrogenase
FLK61_15040	COG2009	succinate dehydrogenase
FLK61_15045	COG1719	4-vinyl reductase, 4VR
FLK61_15050	COG0527	aspartate kinase activity
FLK61_15060	COG0322	excinuclease ABC activity
FLK61_15065	COG3118	belongs to the thioredoxin family
FLK61_15070	COG3534	alpha-L-arabinofuranosidase
FLK61_15075	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FLK61_15080	COG2086	electron transfer activity
FLK61_15085	COG1024	Enoyl-CoA hydratase
FLK61_15090	COG1309	transcriptional regulator
FLK61_15095	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_15100	COG3766	membrane
FLK61_15105	COG1193	negative regulation of DNA recombination
FLK61_15110	COG1796	DNA polymerase
FLK61_15110	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FLK61_15115	COG1286	toxin biosynthetic process
FLK61_15120	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FLK61_15125	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLK61_15130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_15130	COG0072	phenylalanine-tRNA ligase activity
FLK61_15135	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FLK61_15145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLK61_15155	COG3835	regulator
FLK61_15160	COG0277	FAD linked oxidase domain protein
FLK61_15165	COG0247	lactate metabolic process
FLK61_15170	COG0346	lactoylglutathione lyase activity
FLK61_15175	COG1966	Carbon starvation protein
FLK61_15180	COG3534	alpha-L-arabinofuranosidase
FLK61_15185	COG0395	ABC-type sugar transport system, permease component
FLK61_15190	COG1175	transmembrane transport
FLK61_15195	COG1653	transport
FLK61_15200	COG0371	Dehydrogenase
FLK61_15205	COG0647	UMP catabolic process
FLK61_15210	COG0235	Class ii aldolase
FLK61_15215	COG1069	ribulokinase activity
FLK61_15220	COG2160	L-arabinose isomerase activity
FLK61_15230	COG1363	Peptidase, m42
FLK61_15240	COG3326	Membrane
FLK61_15245	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FLK61_15250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FLK61_15255	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FLK61_15265	COG1346	cytolysis
FLK61_15270	COG1380	Effector of murein hydrolase LrgA
FLK61_15275	COG3279	Response regulator of the LytR AlgR family
FLK61_15280	COG3275	phosphorelay sensor kinase activity
FLK61_15290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLK61_15300	COG0398	Pfam SNARE associated Golgi protein
FLK61_15305	COG1484	DNA-dependent DNA replication
FLK61_15310	COG3611	Membrane attachment protein
FLK61_15315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FLK61_15320	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FLK61_15325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLK61_15330	COG1733	regulation of RNA biosynthetic process
FLK61_15335	COG2814	Major facilitator Superfamily
FLK61_15340	COG0656	L-ascorbic acid biosynthetic process
FLK61_15345	COG0237	dephospho-CoA kinase activity
FLK61_15350	COG1971	Probably functions as a manganese efflux pump
FLK61_15355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLK61_15360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK61_15360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK61_15365	COG5002	protein histidine kinase activity
FLK61_15370	COG0745	RESPONSE REGULATOR receiver
FLK61_15375	COG0039	L-malate dehydrogenase activity
FLK61_15380	COG0538	isocitrate dehydrogenase activity
FLK61_15385	COG0372	Belongs to the citrate synthase family
FLK61_15390	COG2707	UPF0756 membrane protein
FLK61_15395	COG0628	permease
FLK61_15400	COG3030	protein affecting phage T7 exclusion by the F plasmid
FLK61_15405	COG0469	pyruvate kinase activity
FLK61_15410	COG0205	6-phosphofructokinase activity
FLK61_15415	COG0825	malonyl-CoA metabolic process
FLK61_15420	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FLK61_15425	COG0281	malic enzyme
FLK61_15430	COG0587	DNA-directed DNA polymerase activity
FLK61_15450	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FLK61_15460	COG4109	DRTGG domain
FLK61_15470	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FLK61_15475	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_15485	COG0165	Argininosuccinate lyase
FLK61_15490	COG0137	argininosuccinate synthase activity
FLK61_15495	COG0521	Mo-molybdopterin cofactor biosynthetic process
FLK61_15500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLK61_15510	COG0827	DNA restriction-modification system
FLK61_15515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FLK61_15520	COG3874	Sporulation protein YtfJ
FLK61_15530	COG1714	RDD family
FLK61_15535	COG0616	signal peptide processing
FLK61_15540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLK61_15545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FLK61_15550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLK61_15560	COG0301	tRNA thio-modification
FLK61_15565	COG1104	cysteine desulfurase activity
FLK61_15570	COG1114	Component of the transport system for branched-chain amino acids
FLK61_15575	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FLK61_15580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FLK61_15585	COG1309	transcriptional regulator
FLK61_15590	COG1956	GAF domain-containing protein
FLK61_15595	COG2199	diguanylate cyclase activity
FLK61_15595	COG2203	Gaf domain
FLK61_15605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FLK61_15610	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLK61_15615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLK61_15620	COG0454	-acetyltransferase
FLK61_15625	COG0517	IMP dehydrogenase activity
FLK61_15630	COG0123	including yeast histone deacetylase and acetoin utilization protein
FLK61_15635	COG1360	Flagellar Motor Protein
FLK61_15640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FLK61_15645	COG1609	Transcriptional regulator
FLK61_15650	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FLK61_15650	COG1605	Chorismate mutase
FLK61_15655	COG3118	belongs to the thioredoxin family
FLK61_15660	COG4980	gas vesicle protein
FLK61_15665	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FLK61_15670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLK61_15675	COG1674	ftsk spoiiie
FLK61_15680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_15685	COG4848	Belongs to the UPF0354 family
FLK61_15690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_15705	COG1363	Peptidase, m42
FLK61_15710	COG5584	Small secreted protein
FLK61_15715	COG0281	malic enzyme
FLK61_15720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_15725	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FLK61_15735	COG0510	thiamine kinase activity
FLK61_15740	COG1523	belongs to the glycosyl hydrolase 13 family
FLK61_15745	COG1597	lipid kinase activity
FLK61_15755	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FLK61_15760	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLK61_15765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLK61_15770	COG2252	PERMEase
FLK61_15775	COG4473	ABC transporter
FLK61_15780	COG1131	(ABC) transporter
FLK61_15785	COG1349	DNA-binding transcription factor activity
FLK61_15790	COG1187	pseudouridine synthase activity
FLK61_15795	COG2244	polysaccharide biosynthetic process
FLK61_15800	COG2081	HI0933 family
FLK61_15805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLK61_15825	COG1653	transport
FLK61_15830	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FLK61_15835	COG4209	transmembrane transport
FLK61_15845	COG1653	transport
FLK61_15850	COG0395	ABC-type sugar transport system, permease component
FLK61_15855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLK61_15860	COG2124	cytochrome p450
FLK61_15880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FLK61_15890	COG1073	alpha beta
FLK61_15915	COG1486	melibiose metabolic process
FLK61_15920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK61_15925	COG0495	leucyl-tRNA aminoacylation
FLK61_15935	COG2202	Pas domain
FLK61_15935	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_15940	COG2814	Major facilitator Superfamily
FLK61_15945	COG2433	Pfam Transposase IS66
FLK61_15950	COG0577	efflux transmembrane transporter activity
FLK61_15955	COG1136	(ABC) transporter
FLK61_15960	COG2205	protein histidine kinase activity
FLK61_15965	COG0745	RESPONSE REGULATOR receiver
FLK61_15970	COG0577	efflux transmembrane transporter activity
FLK61_15975	COG1136	(ABC) transporter
FLK61_15990	COG1131	(ABC) transporter
FLK61_15995	COG1725	Transcriptional regulator
FLK61_16010	COG1242	4 iron, 4 sulfur cluster binding
FLK61_16015	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FLK61_16025	COG2267	carboxylic ester hydrolase activity
FLK61_16030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLK61_16035	COG1113	amino acid transport
FLK61_16040	COG0367	asparagine synthase
FLK61_16045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FLK61_16050	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FLK61_16060	COG1506	peptidase
FLK61_16065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLK61_16070	COG1116	anion transmembrane transporter activity
FLK61_16075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLK61_16080	COG0494	nUDIX hydrolase
FLK61_16085	COG4824	toxin secretion phage lysis holin
FLK61_16090	COG0783	Belongs to the Dps family
FLK61_16105	COG1854	S-ribosylhomocysteine lyase activity
FLK61_16110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FLK61_16115	COG0288	reversible hydration of carbon dioxide
FLK61_16120	COG0254	rRNA binding
FLK61_16125	COG1271	oxidase subunit
FLK61_16130	COG1294	oxidase, subunit
FLK61_16140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK61_16145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK61_16145	COG1321	iron dependent repressor
FLK61_16150	COG1121	(ABC) transporter
FLK61_16155	COG0803	Belongs to the bacterial solute-binding protein 9 family
FLK61_16160	COG4948	Mandelate Racemase Muconate Lactonizing
FLK61_16165	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_16170	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FLK61_16175	COG0596	Alpha beta hydrolase
FLK61_16180	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FLK61_16185	COG1169	isochorismate synthase
FLK61_16195	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLK61_16200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLK61_16205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLK61_16210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLK61_16215	COG0438	transferase activity, transferring glycosyl groups
FLK61_16225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLK61_16230	COG0438	transferase activity, transferring glycosyl groups
FLK61_16235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLK61_16240	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FLK61_16245	COG0058	SHG alpha-glucan phosphorylase activity
FLK61_16250	COG0297	glycogen (starch) synthase activity
FLK61_16255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLK61_16260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLK61_16265	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FLK61_16390	COG3859	Proton-coupled thiamine transporter YuaJ
FLK61_16395	COG1247	-acetyltransferase
FLK61_16400	COG2268	Band 7 protein
FLK61_16405	COG1585	Membrane protein implicated in regulation of membrane protease activity
FLK61_16410	COG2318	DinB family
FLK61_16420	COG1454	alcohol dehydrogenase
FLK61_16430	COG1510	regulation of RNA biosynthetic process
FLK61_16440	COG0569	domain protein
FLK61_16445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLK61_16450	COG4682	membrane
FLK61_16455	COG1705	Flagellar rod assembly protein muramidase FlgJ
FLK61_16460	COG0477	Major facilitator Superfamily
FLK61_16465	COG5553	Cysteine dioxygenase type I
FLK61_16475	COG1968	undecaprenyl-diphosphatase activity
FLK61_16480	COG0628	permease
FLK61_16485	COG0673	inositol 2-dehydrogenase activity
FLK61_16490	COG4806	L-rhamnose isomerase
FLK61_16495	COG3254	rhamnose metabolic process
FLK61_16500	COG1070	Carbohydrate kinase
FLK61_16505	COG1349	DNA-binding transcription factor activity
FLK61_16510	COG3347	Dehydrogenase
FLK61_16510	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_16525	COG0840	transmembrane signaling receptor activity
FLK61_16535	COG0840	transmembrane signaling receptor activity
FLK61_16550	COG0432	Pfam Uncharacterised protein family UPF0047
FLK61_16560	COG0366	Alpha amylase catalytic
FLK61_16565	COG1253	flavin adenine dinucleotide binding
FLK61_16570	COG2738	Putative neutral zinc metallopeptidase
FLK61_16585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLK61_16600	COG0166	Belongs to the GPI family
FLK61_16605	COG1979	alcohol dehydrogenase
FLK61_16610	COG1979	alcohol dehydrogenase
FLK61_16615	COG2155	Conserved Protein
FLK61_16620	COG1098	S1 RNA binding domain
FLK61_16625	COG0436	Aminotransferase
FLK61_16630	COG1522	sequence-specific DNA binding
FLK61_16635	COG2267	carboxylic ester hydrolase activity
FLK61_16645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FLK61_16650	COG2205	protein histidine kinase activity
FLK61_16660	COG5018	Exonuclease
FLK61_16670	COG2814	Major facilitator Superfamily
FLK61_16675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_16680	COG3011	Protein conserved in bacteria
FLK61_16690	COG3290	protein histidine kinase activity
FLK61_16695	COG4565	transcriptional regulatory protein
FLK61_16720	COG3493	citrate carrier protein
FLK61_16730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FLK61_16730	COG2111	Na H antiporter
FLK61_16735	COG2111	Na H antiporter
FLK61_16740	COG1006	Multisubunit Na H antiporter MnhC subunit
FLK61_16745	COG0651	ATP synthesis coupled electron transport
FLK61_16750	COG1863	multisubunit Na H antiporter MnhE subunit
FLK61_16755	COG2212	antiporter activity
FLK61_16760	COG1320	monovalent cation:proton antiporter activity
FLK61_16765	COG2050	protein possibly involved in aromatic compounds catabolism
FLK61_16770	COG2197	response regulator
FLK61_16775	COG4585	Histidine kinase
FLK61_16785	COG0142	geranyltranstransferase activity
FLK61_16805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FLK61_16810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FLK61_16815	COG1335	isochorismatase
FLK61_16820	COG5506	Protein of unknown function (DUF1694)
FLK61_16835	COG0628	permease
FLK61_16850	COG1418	mRNA catabolic process
FLK61_16855	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_16865	COG1511	domain protein
FLK61_16870	COG1674	ftsk spoiiie
FLK61_16870	COG0433	COG0433 Predicted ATPase
FLK61_16875	COG4499	WXG100 protein secretion system (Wss), protein YukC
FLK61_16880	COG5417	Belongs to the EsaB family
FLK61_16885	COG4842	Belongs to the WXG100 family
FLK61_16895	COG2508	Transcriptional regulator
FLK61_16895	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FLK61_16900	COG0686	Belongs to the AlaDH PNT family
FLK61_16905	COG5634	Uncharacterized conserved protein (DUF2278)
FLK61_16910	COG3251	PFAM MbtH domain protein
FLK61_16915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLK61_16920	COG1535	isochorismatase
FLK61_16920	COG3433	isochorismatase activity
FLK61_16925	COG1021	2,3-dihydroxybenzoate-AMP ligase
FLK61_16930	COG1169	isochorismate synthase
FLK61_16935	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_16940	COG2819	hydrolase of the alpha beta superfamily
FLK61_16945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FLK61_16950	COG1268	BioY protein
FLK61_16955	COG2056	Na+-H+ antiporter family
FLK61_16960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLK61_16965	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FLK61_16970	COG3584	3D domain protein
FLK61_16985	COG1252	NADH dehydrogenase
FLK61_16990	COG0492	ferredoxin-NADP+ reductase activity
FLK61_17000	COG0516	GMP reductase activity
FLK61_17005	COG2808	Putative FMN-binding domain
FLK61_17010	COG0456	acetyltransferase
FLK61_17110	COG0582	viral genome integration into host DNA
FLK61_17120	COG4974	Belongs to the 'phage' integrase family
FLK61_17125	COG0316	Belongs to the HesB IscA family
FLK61_17130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FLK61_17135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLK61_17140	COG4844	belongs to the
FLK61_17145	COG1252	NADH dehydrogenase
FLK61_17150	COG4837	Protein of unknown function (DUF1462)
FLK61_17155	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FLK61_17160	COG0823	Involved in the tonB-independent uptake of proteins
FLK61_17160	COG1506	peptidase
FLK61_17160	COG4946	Tricorn protease homolog
FLK61_17165	COG0083	homoserine kinase activity
FLK61_17170	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FLK61_17175	COG0460	homoserine dehydrogenase
FLK61_17180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLK61_17185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FLK61_17190	COG0647	UMP catabolic process
FLK61_17195	COG2445	Protein of unknown function DUF86
FLK61_17200	COG4470	Protein conserved in bacteria
FLK61_17210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FLK61_17215	COG0739	heme binding
FLK61_17225	COG3377	Domain of unknown function (DUF1805)
FLK61_17230	COG0737	Belongs to the 5'-nucleotidase family
FLK61_17235	COG0730	response to heat
FLK61_17240	COG1801	Protein of unknown function DUF72
FLK61_17250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FLK61_17255	COG2508	Transcriptional regulator
FLK61_17260	COG2233	PERMEase
FLK61_17265	COG2233	PERMEase
FLK61_17270	COG3195	allantoin biosynthetic process
FLK61_17270	COG3648	Uricase
FLK61_17275	COG2351	hydroxyisourate hydrolase activity
FLK61_17285	COG2080	2 iron, 2 sulfur cluster binding
FLK61_17290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FLK61_17295	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FLK61_17300	COG2068	MobA-Related Protein
FLK61_17305	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FLK61_17310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FLK61_17315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLK61_17325	COG2356	endonuclease I
FLK61_17330	COG3842	ATPase activity
FLK61_17335	COG2188	Transcriptional regulator
FLK61_17340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_17350	COG1175	transmembrane transport
FLK61_17355	COG1653	transport
FLK61_17360	COG2222	sugar isomerase
FLK61_17365	COG0322	excinuclease ABC activity
FLK61_17370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLK61_17385	COG0346	lactoylglutathione lyase activity
FLK61_17390	COG0640	Transcriptional regulator
FLK61_17395	COG0719	Fe-S assembly protein
FLK61_17400	COG0822	iron-sulfur transferase activity
FLK61_17405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLK61_17410	COG0719	Fe-S assembly protein
FLK61_17415	COG0396	ATPase activity
FLK61_17435	COG1464	Belongs to the NlpA lipoprotein family
FLK61_17440	COG2011	ABC-type metal ion transport system permease component
FLK61_17445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLK61_17455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_17460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FLK61_17470	COG0509	glycine decarboxylation via glycine cleavage system
FLK61_17475	COG1393	Belongs to the ArsC family
FLK61_17480	COG1960	acyl-CoA dehydrogenase activity
FLK61_17485	COG0183	Belongs to the thiolase family
FLK61_17490	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLK61_17490	COG1024	Enoyl-CoA hydratase
FLK61_17510	COG5577	PFAM Coat F domain
FLK61_17515	COG1846	Transcriptional regulator
FLK61_17520	COG0477	Major facilitator Superfamily
FLK61_17525	COG1942	4-Oxalocrotonate Tautomerase
FLK61_17530	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_17535	COG0583	DNA-binding transcription factor activity
FLK61_17545	COG1120	ATPase activity
FLK61_17565	COG1131	(ABC) transporter
FLK61_17610	COG0783	Belongs to the Dps family
FLK61_17615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_17620	COG0745	RESPONSE REGULATOR receiver
FLK61_17625	COG2770	Histidine kinase
FLK61_17625	COG2205	protein histidine kinase activity
FLK61_17635	COG1309	transcriptional regulator
FLK61_17640	COG0114	fumarate hydratase activity
FLK61_17650	COG0697	spore germination
FLK61_17655	COG0814	amino acid
FLK61_17665	COG2197	response regulator
FLK61_17670	COG4585	Histidine kinase
FLK61_17675	COG4758	membrane
FLK61_17680	COG3595	metallopeptidase activity
FLK61_17685	COG1842	Phage shock protein A
FLK61_17690	COG4758	membrane
FLK61_17695	COG2814	Major facilitator Superfamily
FLK61_17700	COG2096	Adenosyltransferase
FLK61_17705	COG1120	ATPase activity
FLK61_17710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_17715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_17720	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_17725	COG3386	PFAM SMP-30 Gluconolaconase
FLK61_17730	COG2205	protein histidine kinase activity
FLK61_17735	COG0745	RESPONSE REGULATOR receiver
FLK61_17755	COG2140	Oxalate decarboxylase
FLK61_17765	COG0577	efflux transmembrane transporter activity
FLK61_17770	COG1136	(ABC) transporter
FLK61_17775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLK61_17780	COG1120	ATPase activity
FLK61_17785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_17790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_17795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_17805	COG0531	amino acid
FLK61_17820	COG1988	membrane-bound metal-dependent
FLK61_17825	COG1368	sulfuric ester hydrolase activity
FLK61_17830	COG1910	domain protein
FLK61_17835	COG0725	ABC transporter, periplasmic molybdate-binding protein
FLK61_17840	COG4149	molybdate abc transporter
FLK61_17845	COG0656	L-ascorbic acid biosynthetic process
FLK61_17855	COG0025	NhaP-type Na H and K H
FLK61_17860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLK61_17865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FLK61_17870	COG3973	AAA domain
FLK61_17880	COG2860	membrane
FLK61_17885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FLK61_17890	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FLK61_17895	COG2217	Heavy metal translocating P-type atpase
FLK61_17900	COG2217	Heavy metal translocating P-type atpase
FLK61_17905	COG2608	mercury ion transmembrane transporter activity
FLK61_17910	COG1937	Protein conserved in bacteria
FLK61_17915	COG0673	inositol 2-dehydrogenase activity
FLK61_17925	COG1289	transmembrane transporter activity
FLK61_17935	COG2076	Multidrug Resistance protein
FLK61_17940	COG1309	transcriptional regulator
FLK61_17945	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_17955	COG5444	nuclease activity
FLK61_17970	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_17970	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLK61_17975	COG4824	toxin secretion phage lysis holin
FLK61_18000	COG1705	Flagellar rod assembly protein muramidase FlgJ
FLK61_18000	COG3942	CHAP domain
FLK61_18225	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FLK61_18230	COG0557	exoribonuclease II activity
FLK61_18235	COG1647	Serine aminopeptidase, S33
FLK61_18240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLK61_18245	COG0596	Alpha beta hydrolase
FLK61_18250	COG1476	TRANSCRIPTIONal
FLK61_18255	COG1396	sequence-specific DNA binding
FLK61_18260	COG1396	sequence-specific DNA binding
FLK61_18265	COG1733	regulation of RNA biosynthetic process
FLK61_18270	COG0840	transmembrane signaling receptor activity
FLK61_18275	COG1174	glycine betaine transport
FLK61_18280	COG1732	Glycine betaine
FLK61_18285	COG1174	glycine betaine transport
FLK61_18290	COG0517	IMP dehydrogenase activity
FLK61_18290	COG1125	glycine betaine transport
FLK61_18295	COG1510	regulation of RNA biosynthetic process
FLK61_18300	COG1174	glycine betaine transport
FLK61_18305	COG1732	Glycine betaine
FLK61_18310	COG1174	glycine betaine transport
FLK61_18315	COG0517	IMP dehydrogenase activity
FLK61_18315	COG1125	glycine betaine transport
FLK61_18320	COG1510	regulation of RNA biosynthetic process
FLK61_18325	COG2095	MarC family integral membrane protein
FLK61_18335	COG3064	Membrane
FLK61_18340	COG4640	response to antibiotic
FLK61_18345	COG0456	acetyltransferase
FLK61_18350	COG0148	phosphopyruvate hydratase activity
FLK61_18355	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FLK61_18360	COG0149	triose-phosphate isomerase activity
FLK61_18365	COG0126	phosphoglycerate kinase activity
FLK61_18370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLK61_18375	COG2390	Transcriptional regulator
FLK61_18380	COG2814	Major facilitator Superfamily
FLK61_18385	COG1609	Transcriptional regulator
FLK61_18390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLK61_18400	COG0583	DNA-binding transcription factor activity
FLK61_18405	COG0697	spore germination
FLK61_18410	COG1113	amino acid transport
FLK61_18420	COG1556	Lactate utilization protein
FLK61_18425	COG1139	Iron-sulfur cluster binding protein
FLK61_18430	COG0247	lactate metabolic process
FLK61_18435	COG2197	response regulator
FLK61_18440	COG4585	Histidine kinase
FLK61_18445	COG0842	Transport permease protein
FLK61_18450	COG1131	(ABC) transporter
FLK61_18470	COG0596	Alpha beta hydrolase
FLK61_18475	COG2208	phosphoserine phosphatase activity
FLK61_18480	COG3867	Arabinogalactan endo-beta-1,4-galactanase
FLK61_18485	COG1874	Beta-galactosidase
FLK61_18490	COG3833	ABC-type maltose transport systems, permease component
FLK61_18495	COG1175	transmembrane transport
FLK61_18500	COG2182	Extracellular solute-binding protein
FLK61_18505	COG1609	Transcriptional regulator
FLK61_18510	COG2186	Transcriptional regulator
FLK61_18515	COG1620	l-lactate permease
FLK61_18520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FLK61_18530	COG5039	Polysaccharide pyruvyl transferase
FLK61_18535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLK61_18540	COG0110	maltose O-acetyltransferase activity
FLK61_18545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FLK61_18550	COG2244	polysaccharide biosynthetic process
FLK61_18555	COG1216	Glycosyl transferase, family 2
FLK61_18560	COG5039	Polysaccharide pyruvyl transferase
FLK61_18565	COG1216	Glycosyl transferase, family 2
FLK61_18575	COG0438	transferase activity, transferring glycosyl groups
FLK61_18580	COG1215	transferase activity, transferring glycosyl groups
FLK61_18585	COG0438	transferase activity, transferring glycosyl groups
FLK61_18590	COG1086	Polysaccharide biosynthesis protein
FLK61_18595	COG0489	protein tyrosine kinase activity
FLK61_18600	COG3944	biosynthesis protein
FLK61_18605	COG1396	sequence-specific DNA binding
FLK61_18610	COG2272	Belongs to the type-B carboxylesterase lipase family
FLK61_18620	COG3479	Phenolic acid decarboxylase
FLK61_18635	COG1794	racemase activity, acting on amino acids and derivatives
FLK61_18645	COG1621	beta-fructofuranosidase activity
FLK61_18650	COG1621	beta-fructofuranosidase activity
FLK61_18655	COG0531	amino acid
FLK61_18660	COG1309	transcriptional regulator
FLK61_18665	COG2076	Multidrug Resistance protein
FLK61_18670	COG2076	Multidrug Resistance protein
FLK61_18690	COG1674	ftsk spoiiie
FLK61_18710	COG1388	LysM domain
FLK61_18710	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_18710	COG5632	N-Acetylmuramoyl-L-alanine amidase
FLK61_18745	COG1705	Flagellar rod assembly protein muramidase FlgJ
FLK61_18825	COG0582	viral genome integration into host DNA
FLK61_18925	COG4974	Belongs to the 'phage' integrase family
FLK61_18935	COG0740	serine-type endopeptidase activity
FLK61_18940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLK61_18945	COG0366	Alpha amylase catalytic
FLK61_18950	COG1554	hydrolase, family 65, central catalytic
FLK61_18955	COG5521	maltodextrose utilization protein MalA
FLK61_18960	COG3833	ABC-type maltose transport systems, permease component
FLK61_18965	COG1175	transmembrane transport
FLK61_18970	COG2182	Extracellular solute-binding protein
FLK61_18980	COG1609	Transcriptional regulator
FLK61_18985	COG1611	Belongs to the LOG family
FLK61_18995	COG0659	secondary active sulfate transmembrane transporter activity
FLK61_19000	COG0288	reversible hydration of carbon dioxide
FLK61_19005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLK61_19010	COG0577	efflux transmembrane transporter activity
FLK61_19015	COG1136	(ABC) transporter
FLK61_19020	COG5002	protein histidine kinase activity
FLK61_19025	COG0745	RESPONSE REGULATOR receiver
FLK61_19035	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FLK61_19040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_19045	COG1481	regulation of sporulation
FLK61_19050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FLK61_19055	COG1660	Displays ATPase and GTPase activities
FLK61_19060	COG1051	belongs to the nudix hydrolase family
FLK61_19065	COG0492	ferredoxin-NADP+ reductase activity
FLK61_19070	COG0791	NLP P60 protein
FLK61_19070	COG3883	PFAM NLP P60 protein
FLK61_19075	COG0457	Tetratricopeptide repeat
FLK61_19080	COG1132	(ABC) transporter
FLK61_19100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLK61_19100	COG0140	phosphoribosyl-ATP diphosphatase activity
FLK61_19105	COG0107	imidazoleglycerol-phosphate synthase activity
FLK61_19110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FLK61_19115	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLK61_19120	COG0131	Imidazoleglycerol-phosphate dehydratase
FLK61_19125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FLK61_19130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FLK61_19135	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FLK61_19140	COG4990	cell redox homeostasis
FLK61_19145	COG5297	Belongs to the glycosyl hydrolase family 6
FLK61_19160	COG0546	phosphoglycolate phosphatase activity
FLK61_19165	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FLK61_19170	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FLK61_19175	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FLK61_19180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLK61_19185	COG0363	glucosamine-6-phosphate deaminase activity
FLK61_19195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FLK61_19210	COG1950	PFAM Membrane protein of
FLK61_19215	COG1983	PspC domain protein
FLK61_19220	COG3595	metallopeptidase activity
FLK61_19235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLK61_19240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FLK61_19245	COG0556	nucleotide-excision repair
FLK61_19250	COG4897	Protein conserved in bacteria
FLK61_19255	COG0574	Belongs to the PEP-utilizing enzyme family
FLK61_19255	COG3848	Pyruvate phosphate dikinase
FLK61_19260	COG1309	transcriptional regulator
FLK61_19265	COG2814	Major facilitator Superfamily
FLK61_19270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_19280	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_19280	COG0793	Belongs to the peptidase S41A family
FLK61_19285	COG2177	Part of the ABC transporter FtsEX involved in
FLK61_19290	COG2884	Cell division ATP-binding protein ftsE
FLK61_19295	COG2010	Cytochrome c
FLK61_19300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_19310	COG0653	protein targeting
FLK61_19315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLK61_19330	COG1516	flagellar protein fliS
FLK61_19335	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FLK61_19340	COG1334	flagellar protein FlaG
FLK61_19345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLK61_19350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FLK61_19355	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FLK61_19365	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLK61_19370	COG1256	bacterial-type flagellum assembly
FLK61_19370	COG4786	Flagellar basal body rod
FLK61_19375	COG3418	PFAM FlgN family protein
FLK61_19380	COG2747	anti-sigma28 factor FlgM
FLK61_19390	COG1040	competence protein
FLK61_19400	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FLK61_19405	COG1307	EDD domain protein, DegV family
FLK61_19410	COG2197	response regulator
FLK61_19415	COG4585	Histidine kinase
FLK61_19420	COG1739	Uncharacterized protein family UPF0029
FLK61_19425	COG1316	TRANSCRIPTIONal
FLK61_19460	COG1131	(ABC) transporter
FLK61_19470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLK61_19475	COG0438	transferase activity, transferring glycosyl groups
FLK61_19480	COG1215	transferase activity, transferring glycosyl groups
FLK61_19485	COG3206	protein involved in exopolysaccharide biosynthesis
FLK61_19490	COG3307	-O-antigen
FLK61_19500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLK61_19505	COG0297	glycogen (starch) synthase activity
FLK61_19505	COG0438	transferase activity, transferring glycosyl groups
FLK61_19510	COG2244	polysaccharide biosynthetic process
FLK61_19525	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_19525	COG2247	cell wall binding repeat
FLK61_19530	COG2385	sporulation resulting in formation of a cellular spore
FLK61_19530	COG2247	cell wall binding repeat
FLK61_19560	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FLK61_19565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLK61_19575	COG1134	teichoic acid transport
FLK61_19580	COG1682	transport, permease protein
FLK61_19595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLK61_19595	COG0463	Glycosyl transferase, family 2
FLK61_19600	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLK61_19605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FLK61_19610	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FLK61_19615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLK61_19620	COG4193	domain, Protein
FLK61_19625	COG1482	cell wall glycoprotein biosynthetic process
FLK61_19630	COG0697	spore germination
FLK61_19635	COG0814	amino acid
FLK61_19650	COG1316	TRANSCRIPTIONal
FLK61_19655	COG0561	phosphatase activity
FLK61_19660	COG0791	NLP P60 protein
FLK61_19670	COG2843	Capsule synthesis protein
FLK61_19680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLK61_19690	COG1609	Transcriptional regulator
FLK61_19695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_19700	COG1869	D-ribose catabolic process
FLK61_19705	COG1129	ABC transporter
FLK61_19710	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLK61_19715	COG1879	ABC-type sugar transport system periplasmic component
FLK61_19720	COG3103	Sh3 type 3 domain protein
FLK61_19730	COG2249	NAD(P)H dehydrogenase (quinone) activity
FLK61_19735	COG3527	Alpha-acetolactate decarboxylase
FLK61_19740	COG0028	Belongs to the TPP enzyme family
FLK61_19745	COG0583	DNA-binding transcription factor activity
FLK61_19750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLK61_19765	COG5337	Spore coat protein CotH
FLK61_19775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLK61_19785	COG0405	Gamma-glutamyltransferase
FLK61_19790	COG1522	sequence-specific DNA binding
FLK61_19795	COG2059	Chromate
FLK61_19800	COG2059	Chromate
FLK61_19810	COG0655	NAD(P)H dehydrogenase (quinone) activity
FLK61_19815	COG0583	DNA-binding transcription factor activity
FLK61_19845	COG5444	nuclease activity
FLK61_19870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLK61_19875	COG4464	protein tyrosine phosphatase activity
FLK61_19880	COG0489	protein tyrosine kinase activity
FLK61_19885	COG3944	biosynthesis protein
FLK61_19895	COG4715	Zinc finger, swim domain protein
FLK61_19900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLK61_19910	COG0561	phosphatase activity
FLK61_19915	COG1349	DNA-binding transcription factor activity
FLK61_19920	COG0629	single-stranded DNA binding
FLK61_19935	COG3764	Sortase (surface protein transpeptidase)
FLK61_19945	COG2972	Histidine kinase
FLK61_19945	COG0745	RESPONSE REGULATOR receiver
FLK61_19950	COG1970	mechanosensitive ion channel activity
FLK61_19955	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FLK61_19960	COG0457	Tetratricopeptide repeat
FLK61_19965	COG4786	Flagellar basal body rod
FLK61_19970	COG4786	Flagellar basal body rod
FLK61_19975	COG1077	Cell shape determining protein MreB Mrl
FLK61_19980	COG1609	Transcriptional regulator
FLK61_19990	COG1846	Transcriptional regulator
FLK61_19995	COG2814	Major facilitator Superfamily
FLK61_20000	COG3420	alginic acid biosynthetic process
FLK61_20005	COG1953	Uracil, thiamine, allantoin
FLK61_20010	COG0477	Major facilitator Superfamily
FLK61_20015	COG1335	isochorismatase
FLK61_20025	COG0004	ammonium transporteR
FLK61_20030	COG0347	Belongs to the P(II) protein family
FLK61_20035	COG0671	phosphoesterase, PA-phosphatase related
FLK61_20045	COG0739	heme binding
FLK61_20050	COG1247	-acetyltransferase
FLK61_20060	COG2089	acid synthase
FLK61_20070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLK61_20075	COG0789	Transcriptional regulator
FLK61_20085	COG2910	NAD(P)H-binding
FLK61_20090	COG1959	2 iron, 2 sulfur cluster binding
FLK61_20095	COG0804	urea catabolic process
FLK61_20100	COG0832	Belongs to the urease beta subunit family
FLK61_20105	COG0831	urea catabolic process
FLK61_20120	COG3237	CsbD-like
FLK61_20125	COG1994	Peptidase M50
FLK61_20130	COG0457	Tetratricopeptide repeat
FLK61_20135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FLK61_20140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FLK61_20150	COG2304	oxidoreductase activity
FLK61_20160	COG2304	oxidoreductase activity
FLK61_20165	COG2385	sporulation resulting in formation of a cellular spore
FLK61_20170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLK61_20180	COG4836	Membrane
FLK61_20190	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FLK61_20195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FLK61_20200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FLK61_20205	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FLK61_20210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLK61_20215	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLK61_20220	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLK61_20225	COG0356	it plays a direct role in the translocation of protons across the membrane
FLK61_20235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FLK61_20240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FLK61_20245	COG4475	Protein of unknown function (DUF436)
FLK61_20250	COG0698	ribose 5-phosphate isomerase
FLK61_20255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLK61_20260	COG1971	Probably functions as a manganese efflux pump
FLK61_20265	COG0009	L-threonylcarbamoyladenylate synthase
FLK61_20270	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FLK61_20290	COG2890	protein-(glutamine-N5) methyltransferase activity
FLK61_20295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FLK61_20300	COG0346	lactoylglutathione lyase activity
FLK61_20305	COG0789	Transcriptional regulator
FLK61_20310	COG0679	Auxin Efflux Carrier
FLK61_20315	COG0281	malic enzyme
FLK61_20320	COG1435	thymidine kinase activity
FLK61_20325	COG0254	rRNA binding
FLK61_20330	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FLK61_20340	COG1494	fructose-1,6-bisphosphatase
FLK61_20345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLK61_20350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLK61_20355	COG0191	fructose-bisphosphate aldolase activity
FLK61_20360	COG2204	response regulator
FLK61_20365	COG4821	SIS domain
FLK61_20370	COG0504	CTP synthase activity
FLK61_20375	COG3343	RNA polymerase activity
FLK61_20380	COG1960	acyl-CoA dehydrogenase activity
FLK61_20385	COG0247	lactate metabolic process
FLK61_20385	COG2181	nitrate reductase activity
FLK61_20390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLK61_20395	COG4294	response to UV
FLK61_20405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLK61_20415	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLK61_20425	COG2181	nitrate reductase activity
FLK61_20430	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FLK61_20435	COG1140	nitrate reductase beta subunit
FLK61_20440	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FLK61_20445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLK61_20455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLK61_20460	COG2223	nitrite transmembrane transporter activity
FLK61_20465	COG0018	arginyl-trna synthetase
FLK61_20470	COG4506	Protein conserved in bacteria
FLK61_20485	COG0535	radical SAM domain protein
FLK61_20495	COG1131	(ABC) transporter
FLK61_20500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FLK61_20505	COG0612	Peptidase, M16
FLK61_20510	COG0612	Peptidase, M16
FLK61_20520	COG3391	amine dehydrogenase activity
FLK61_20525	COG3391	amine dehydrogenase activity
FLK61_20535	COG0457	Tetratricopeptide repeat
FLK61_20545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLK61_20550	COG0010	Belongs to the arginase family
FLK61_20555	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FLK61_20560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_20575	COG1994	Peptidase M50
FLK61_20580	COG1942	4-Oxalocrotonate Tautomerase
FLK61_20585	COG1846	Transcriptional regulator
FLK61_20590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLK61_20600	COG0477	Major facilitator Superfamily
FLK61_20605	COG1959	2 iron, 2 sulfur cluster binding
FLK61_20610	COG3465	dGTPase activity
FLK61_20615	COG1078	dGTPase activity
FLK61_20620	COG4844	belongs to the
FLK61_20630	COG0697	spore germination
FLK61_20635	COG0095	Lipoate-protein ligase
FLK61_20640	COG0583	DNA-binding transcription factor activity
FLK61_20645	COG0280	phosphate acetyltransferase
FLK61_20655	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_20660	COG0436	Aminotransferase
FLK61_20665	COG2814	Major facilitator Superfamily
FLK61_20670	COG0151	Belongs to the GarS family
FLK61_20675	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_20680	COG1917	Cupin 2, conserved barrel domain protein
FLK61_20685	COG0077	Prephenate dehydratase
FLK61_20690	COG2814	Major facilitator Superfamily
FLK61_20695	COG0833	amino acid
FLK61_20700	COG4187	Peptidase family M20/M25/M40
FLK61_20705	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_20710	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLK61_20720	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FLK61_20725	COG1091	dTDP-4-dehydrorhamnose reductase activity
FLK61_20730	COG1088	dTDP-glucose 4,6-dehydratase activity
FLK61_20735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FLK61_20740	COG3980	spore coat polysaccharide biosynthesis protein
FLK61_20745	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
FLK61_20750	COG2089	acid synthase
FLK61_20755	COG0456	acetyltransferase
FLK61_20760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLK61_20765	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLK61_20770	COG0463	Glycosyl transferase, family 2
FLK61_20785	COG2363	Small membrane protein
FLK61_20790	COG2233	PERMEase
FLK61_20800	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_20805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FLK61_20810	COG1216	Glycosyl transferase, family 2
FLK61_20815	COG0351	phosphomethylpyrimidine kinase
FLK61_20825	COG1621	beta-fructofuranosidase activity
FLK61_20830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_20830	COG1263	PTS System
FLK61_20835	COG2116	formate transmembrane transporter activity
FLK61_20850	COG1404	Belongs to the peptidase S8 family
FLK61_20855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLK61_20860	COG0778	Nitroreductase
FLK61_20865	COG0772	Belongs to the SEDS family
FLK61_20880	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FLK61_20885	COG1845	cytochrome c oxidase, subunit III
FLK61_20890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLK61_20895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FLK61_20900	COG2261	transglycosylase associated protein
FLK61_20905	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FLK61_20910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FLK61_20915	COG2246	polysaccharide biosynthetic process
FLK61_20920	COG1309	transcriptional regulator
FLK61_20930	COG3162	membrane
FLK61_20935	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK61_20940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FLK61_20945	COG2837	iron assimilation
FLK61_20950	COG2822	iron ion transport
FLK61_20955	COG0672	)-iron permease
FLK61_20960	COG0352	thiamine-phosphate diphosphorylase activity
FLK61_20965	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FLK61_20970	COG0583	DNA-binding transcription factor activity
FLK61_20975	COG1380	Effector of murein hydrolase LrgA
FLK61_20980	COG1346	cytolysis
FLK61_20985	COG2814	Major facilitator Superfamily
FLK61_20990	COG4895	conserved protein (DUF2196)
FLK61_20995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FLK61_21000	COG0346	lactoylglutathione lyase activity
FLK61_21010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLK61_21020	COG1263	PTS System
FLK61_21020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_21025	COG3711	transcriptional antiterminator
FLK61_21030	COG1442	glycosyl transferase family 8
FLK61_21035	COG5522	Integral membrane protein (intg_mem_TP0381)
FLK61_21040	COG1846	Transcriptional regulator
FLK61_21045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLK61_21050	COG2234	aminopeptidase activity
FLK61_21055	COG2357	RelA SpoT domain protein
FLK61_21065	COG1575	Belongs to the MenA family. Type 1 subfamily
FLK61_21085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FLK61_21090	COG1696	Membrane protein involved in D-alanine export
FLK61_21095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLK61_21100	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FLK61_21110	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK61_21115	COG1486	melibiose metabolic process
FLK61_21120	COG1447	Phosphotransferase system cellobiose-specific component IIA
FLK61_21125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLK61_21130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FLK61_21135	COG3711	transcriptional antiterminator
FLK61_21135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_21145	COG2094	Belongs to the DNA glycosylase MPG family
FLK61_21150	COG0753	catalase activity
FLK61_21155	COG2814	Major facilitator Superfamily
FLK61_21160	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FLK61_21165	COG1131	(ABC) transporter
FLK61_21185	COG1595	DNA-templated transcription, initiation
FLK61_21190	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FLK61_21195	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FLK61_21200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLK61_21205	COG4988	ABC transporter
FLK61_21210	COG1294	oxidase, subunit
FLK61_21215	COG1271	oxidase subunit
FLK61_21220	COG3493	citrate carrier protein
FLK61_21225	COG0501	Belongs to the peptidase M48B family
FLK61_21235	COG0726	polysaccharide deacetylase
FLK61_21240	COG3842	ATPase activity
FLK61_21245	COG2508	Transcriptional regulator
FLK61_21250	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_21255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_21260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FLK61_21270	COG4585	Histidine kinase
FLK61_21275	COG2197	response regulator
FLK61_21280	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLK61_21290	COG4894	glucomannan catabolic process
FLK61_21295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FLK61_21300	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FLK61_21305	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_21310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FLK61_21315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLK61_21320	COG2610	gluconate transmembrane transporter activity
FLK61_21325	COG0500	methyltransferase
FLK61_21330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLK61_21345	COG0693	protein deglycase activity
FLK61_21345	COG0753	catalase activity
FLK61_21350	COG2851	Citrate transporter
FLK61_21355	COG2273	Hydrolase Family 16
FLK61_21360	COG3711	transcriptional antiterminator
FLK61_21375	COG2270	Major facilitator Superfamily
FLK61_21380	COG0513	Belongs to the DEAD box helicase family
FLK61_21385	COG2755	lipolytic protein G-D-S-L family
FLK61_21385	COG3401	FG-GAP repeat protein
FLK61_21515	COG0589	response to stress
FLK61_21525	COG2190	(PTS) system
FLK61_21525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_21525	COG1263	PTS System
FLK61_21545	COG5444	nuclease activity
FLK61_21565	COG0494	nUDIX hydrolase
FLK61_21570	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FLK61_21575	COG3507	Belongs to the glycosyl hydrolase 43 family
FLK61_21590	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FLK61_21595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLK61_21600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FLK61_21605	COG2390	Transcriptional regulator
FLK61_21615	COG3192	ethanolamine utilization protein
FLK61_21620	COG2079	MmgE PrpD family protein
FLK61_21630	COG1126	abc transporter atp-binding protein
FLK61_21635	COG0765	amino acid transport
FLK61_21640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK61_21655	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FLK61_21660	COG0561	phosphatase activity
FLK61_21690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_21695	COG5294	Protein conserved in bacteria
FLK61_21710	COG2205	protein histidine kinase activity
FLK61_21715	COG0745	RESPONSE REGULATOR receiver
FLK61_21720	COG0191	fructose-bisphosphate aldolase activity
FLK61_21725	COG1082	Xylose isomerase domain protein TIM barrel
FLK61_21730	COG1082	Xylose isomerase domain protein TIM barrel
FLK61_21735	COG0673	inositol 2-dehydrogenase activity
FLK61_21740	COG2814	Major facilitator Superfamily
FLK61_21745	COG1082	Xylose isomerase domain protein TIM barrel
FLK61_21750	COG3962	Belongs to the TPP enzyme family
FLK61_21755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_21775	COG1349	DNA-binding transcription factor activity
FLK61_21780	COG0667	Aldo Keto reductase
FLK61_21810	COG0326	Molecular chaperone. Has ATPase activity
FLK61_21870	COG1917	Cupin 2, conserved barrel domain protein
FLK61_21875	COG1309	transcriptional regulator
FLK61_21880	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_21885	COG1846	Transcriptional regulator
FLK61_21890	COG1380	Effector of murein hydrolase LrgA
FLK61_21895	COG1346	cytolysis
FLK61_21900	COG5039	Polysaccharide pyruvyl transferase
FLK61_21905	COG1929	Belongs to the glycerate kinase type-1 family
FLK61_21910	COG1802	Transcriptional regulator
FLK61_21915	COG1070	Carbohydrate kinase
FLK61_21920	COG2610	gluconate transmembrane transporter activity
FLK61_21925	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLK61_21930	COG0450	alkyl hydroperoxide reductase
FLK61_21935	COG3634	alkyl hydroperoxide reductase activity
FLK61_21940	COG2723	6-phospho-beta-galactosidase activity
FLK61_21955	COG2188	Transcriptional regulator
FLK61_21965	COG1131	(ABC) transporter
FLK61_21970	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
FLK61_21985	COG0071	Belongs to the small heat shock protein (HSP20) family
FLK61_22020	COG0210	DNA helicase
FLK61_22050	COG2963	transposase activity
FLK61_22085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FLK61_22100	COG1063	alcohol dehydrogenase
FLK61_22120	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FLK61_22125	COG0456	acetyltransferase
FLK61_22130	COG0457	Tetratricopeptide repeat
FLK61_22140	COG0010	Belongs to the arginase family
FLK61_22145	COG0833	amino acid
FLK61_22150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLK61_22170	COG5658	integral membrane protein
FLK61_22175	COG0640	Transcriptional regulator
FLK61_22180	COG3829	transcription factor binding
FLK61_22195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_22200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FLK61_22205	COG4853	Protein conserved in bacteria
FLK61_22210	COG4863	YycH protein
FLK61_22215	COG5002	protein histidine kinase activity
FLK61_22220	COG0745	RESPONSE REGULATOR receiver
FLK61_22250	COG0346	lactoylglutathione lyase activity
FLK61_22255	COG0305	Participates in initiation and elongation during chromosome replication
FLK61_22270	COG3093	addiction module antidote protein HigA
FLK61_22275	COG2807	transmembrane transport
FLK61_22280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FLK61_22285	COG0359	binds to the 23S rRNA
FLK61_22290	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FLK61_22295	COG4241	membrane
FLK61_22310	COG1733	regulation of RNA biosynthetic process
FLK61_22315	COG1227	inorganic diphosphatase activity
FLK61_22325	COG2271	Major facilitator Superfamily
FLK61_22330	COG4978	Transcriptional regulator
FLK61_22330	COG0789	Transcriptional regulator
FLK61_22340	COG4319	ketosteroid isomerase
FLK61_22345	COG1357	PFAM Pentapeptide repeats (8 copies)
FLK61_22360	COG1846	Transcriptional regulator
FLK61_22365	COG2153	protein acetylation
FLK61_22370	COG2364	Membrane
FLK61_22375	COG0456	acetyltransferase
FLK61_22380	COG2315	Protein conserved in bacteria
FLK61_22385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLK61_22390	COG1331	Highly conserved protein containing a thioredoxin domain
FLK61_22395	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FLK61_22400	COG1331	Highly conserved protein containing a thioredoxin domain
FLK61_22405	COG1266	CAAX protease self-immunity
FLK61_22410	COG0477	Major facilitator Superfamily
FLK61_22410	COG2814	Major facilitator Superfamily
FLK61_22415	COG0346	lactoylglutathione lyase activity
FLK61_22420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLK61_22425	COG0542	response to heat
FLK61_22440	COG0708	Exodeoxyribonuclease III
FLK61_22445	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FLK61_22450	COG0629	single-stranded DNA binding
FLK61_22455	COG0360	Binds together with S18 to 16S ribosomal RNA
FLK61_22460	COG0012	GTP binding
FLK61_22465	COG0243	molybdopterin cofactor binding
FLK61_22470	COG4481	Protein conserved in bacteria
FLK61_22475	COG3949	Membrane
FLK61_22485	COG1475	DNA binding
FLK61_22490	COG1192	Involved in chromosome partitioning
FLK61_22500	COG1475	DNA binding
FLK61_22505	COG0357	Ribosomal RNA small subunit methyltransferase G
FLK61_22510	COG0445	tRNA wobble uridine modification
FLK61_22515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FLK61_22520	COG1847	R3H domain protein
FLK61_22525	COG0706	membrane insertase activity
FLK61_22530	COG0594	ribonuclease P activity
FLK61_22535	COG0230	Belongs to the bacterial ribosomal protein bL34 family