locus-tag	class	description
FLK61_00130	COG0791	NLP P60 protein
FLK61_00130	COG3883	PFAM NLP P60 protein
FLK61_00185	COG0629	single-stranded DNA binding
FLK61_00200	COG0582	viral genome integration into host DNA
FLK61_00230	COG1793	dna ligase
FLK61_00245	COG1525	nuclease
FLK61_00345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLK61_00390	COG0457	Tetratricopeptide repeat
FLK61_01120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FLK61_01125	COG0049	tRNA binding
FLK61_01130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLK61_01135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLK61_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FLK61_01155	COG0088	Forms part of the polypeptide exit tunnel
FLK61_01160	COG0089	rRNA binding
FLK61_01165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FLK61_01170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLK61_01175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FLK61_01180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLK61_01185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLK61_01190	COG0255	Belongs to the universal ribosomal protein uL29 family
FLK61_01195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FLK61_01200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FLK61_01205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FLK61_01210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FLK61_01215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLK61_01220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FLK61_01225	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FLK61_01230	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FLK61_01235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FLK61_01240	COG1841	ribosomal large subunit assembly
FLK61_01250	COG0201	protein transport
FLK61_20195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FLK61_22540	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLK61_22545	COG0592	DNA-directed DNA polymerase activity
FLK61_22550	COG2501	S4 domain
FLK61_22555	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLK61_22565	COG0187	DNA topoisomerase II activity
FLK61_22570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLK61_22575	COG3437	response regulator, receiver
FLK61_22585	COG0517	IMP dehydrogenase activity
FLK61_22585	COG0516	GMP reductase activity
FLK61_22595	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FLK61_22600	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FLK61_22610	COG0444	Belongs to the ABC transporter superfamily
FLK61_22615	COG4608	Belongs to the ABC transporter superfamily
FLK61_22620	COG4166	transmembrane transport
FLK61_22625	COG0601	transmembrane transport
FLK61_22630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLK61_22635	COG0590	tRNA wobble adenosine to inosine editing
FLK61_22640	COG3093	addiction module antidote protein HigA
FLK61_22650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLK61_22655	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FLK61_22660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FLK61_22695	COG1982	Orn Lys Arg decarboxylase major
FLK61_22700	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FLK61_22705	COG3870	Protein conserved in bacteria
FLK61_22710	COG0470	DNA polymerase III
FLK61_22715	COG1774	PSP1 C-terminal conserved region
FLK61_22720	COG4467	Involved in initiation control of chromosome replication
FLK61_22725	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FLK61_22730	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLK61_22735	COG2002	toxin-antitoxin pair type II binding
FLK61_22740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_22740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_22745	COG0084	hydrolase, TatD family'
FLK61_22750	COG3583	domain protein
FLK61_22750	COG3584	3D domain protein
FLK61_22760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FLK61_22770	COG4466	Protein conserved in bacteria
FLK61_22775	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLK61_22780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLK61_22785	COG2088	sporulation resulting in formation of a cellular spore
FLK61_22790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLK61_22795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLK61_22800	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FLK61_22805	COG0193	aminoacyl-tRNA hydrolase activity
FLK61_22815	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLK61_22820	COG2002	toxin-antitoxin pair type II binding
FLK61_22825	COG2244	polysaccharide biosynthetic process
FLK61_22830	COG3956	TIGRFAM MazG family protein
FLK61_22835	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FLK61_22855	COG1098	S1 RNA binding domain
FLK61_22860	COG2208	phosphoserine phosphatase activity
FLK61_22865	COG2304	oxidoreductase activity
FLK61_22870	COG0515	serine threonine protein kinase
FLK61_22875	COG2966	Psort location CytoplasmicMembrane, score
FLK61_22885	COG0037	tRNA processing
FLK61_22905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FLK61_22910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLK61_22915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLK61_22920	COG0512	Glutamine amidotransferase of anthranilate synthase
FLK61_22925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK61_22930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FLK61_22935	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLK61_22940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLK61_22945	COG1396	sequence-specific DNA binding
FLK61_22950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FLK61_22985	COG3880	PFAM UvrB UvrC protein
FLK61_22990	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FLK61_22995	COG0542	response to heat
FLK61_23000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLK61_23005	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FLK61_23010	COG4956	integral membrane protein (PIN domain superfamily)
FLK61_23015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FLK61_23025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLK61_23030	COG1045	serine acetyltransferase
FLK61_23035	COG0215	cysteine-tRNA ligase activity
FLK61_23045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLK61_23050	COG3688	RNA-binding protein containing a PIN domain
FLK61_23060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FLK61_23065	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLK61_23070	COG0250	Participates in transcription elongation, termination and antitermination
FLK61_23075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FLK61_23080	COG0081	regulation of translation
FLK61_23085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FLK61_23090	COG0222	ribosome binding
FLK61_23095	COG2813	Specifically methylates the guanine in position
FLK61_23100	COG0085	RNA polymerase activity
FLK61_23105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLK61_23110	COG1358	cellular component organization or biogenesis
FLK61_23120	COG0563	adenylate kinase activity
FLK61_23125	COG0024	Methionine aminopeptidase
FLK61_23130	COG2163	COG2163 Ribosomal protein L14E L6E L27E
FLK61_23135	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FLK61_23140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FLK61_23145	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FLK61_23150	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FLK61_23155	COG0202	RNA polymerase activity
FLK61_23160	COG0203	ribosomal protein L17
FLK61_23170	COG1122	ATPase activity
FLK61_23175	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLK61_23180	COG0101	tRNA pseudouridine synthase activity
FLK61_23185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FLK61_23190	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FLK61_23195	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_23200	COG3386	PFAM SMP-30 Gluconolaconase
FLK61_23255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FLK61_23285	COG2186	Transcriptional regulator
FLK61_23290	COG1556	Lactate utilization protein
FLK61_23295	COG1139	Iron-sulfur cluster binding protein
FLK61_23300	COG0247	lactate metabolic process
FLK61_23305	COG0800	Aldolase
FLK61_23310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_23315	COG2721	sulfolactate sulfo-lyase activity
FLK61_23320	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_23325	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FLK61_23330	COG2207	Transcriptional regulator
FLK61_23330	COG4753	response regulator
FLK61_23335	COG2972	Histidine kinase
FLK61_23340	COG5578	integral membrane protein
FLK61_23345	COG0395	ABC-type sugar transport system, permease component
FLK61_23350	COG1175	transmembrane transport
FLK61_23355	COG1653	transport
FLK61_23360	COG1609	Transcriptional regulator
FLK61_23365	COG1904	glucuronate isomerase
FLK61_23370	COG0246	Mannitol dehydrogenase
FLK61_23375	COG0673	inositol 2-dehydrogenase activity
FLK61_23390	COG1349	DNA-binding transcription factor activity
FLK61_23405	COG3401	FG-GAP repeat protein
FLK61_23415	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FLK61_23420	COG0823	Involved in the tonB-independent uptake of proteins
FLK61_23430	COG1653	transport
FLK61_23435	COG4209	transmembrane transport
FLK61_23440	COG0395	ABC-type sugar transport system, permease component
FLK61_23445	COG2207	Transcriptional regulator
FLK61_23460	COG4806	L-rhamnose isomerase
FLK61_23465	COG1070	Carbohydrate kinase
FLK61_23470	COG3347	Dehydrogenase
FLK61_23470	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_23475	COG1349	DNA-binding transcription factor activity
FLK61_23495	COG1063	alcohol dehydrogenase
FLK61_23505	COG0747	negative chemotaxis
FLK61_23510	COG0601	transmembrane transport
FLK61_23515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLK61_23520	COG0444	Belongs to the ABC transporter superfamily
FLK61_23525	COG4608	Belongs to the ABC transporter superfamily
FLK61_23530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLK61_23545	COG0515	serine threonine protein kinase
FLK61_23550	COG0745	RESPONSE REGULATOR receiver
FLK61_23555	COG5002	protein histidine kinase activity
FLK61_23580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLK61_23600	COG0456	acetyltransferase
FLK61_23605	COG0386	Belongs to the glutathione peroxidase family
FLK61_23640	COG0579	oxidoreductase
FLK61_23645	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLK61_23650	COG5001	Diguanylate cyclase
FLK61_23650	COG3300	MHYT domain
FLK61_23655	COG1979	alcohol dehydrogenase
FLK61_23660	COG4821	SIS domain
FLK61_23680	COG0210	DNA helicase
FLK61_23685	COG0352	thiamine-phosphate diphosphorylase activity
FLK61_23690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLK61_23700	COG2022	thiamine diphosphate biosynthetic process
FLK61_23705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FLK61_23725	COG4607	ABC-type enterochelin transport system periplasmic component
FLK61_23730	COG4604	ABC transporter, ATP-binding protein
FLK61_23735	COG4605	iron ion homeostasis
FLK61_23740	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_23750	COG1215	transferase activity, transferring glycosyl groups
FLK61_23755	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FLK61_23765	COG1902	pentaerythritol trinitrate reductase activity
FLK61_23775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_23780	COG0791	NLP P60 protein
FLK61_23780	COG1388	LysM domain
FLK61_23790	COG0673	inositol 2-dehydrogenase activity
FLK61_23815	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_23820	COG0489	protein tyrosine kinase activity
FLK61_23830	COG2194	sulfuric ester hydrolase activity
FLK61_23835	COG0726	polysaccharide deacetylase
FLK61_23855	COG1595	DNA-templated transcription, initiation
FLK61_23860	COG5662	AntiSigma factor
FLK61_23865	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLK61_23870	COG4856	YbbR-like protein
FLK61_23915	COG2801	Transposase and inactivated derivatives
FLK61_23920	COG0246	Mannitol dehydrogenase
FLK61_23925	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_23930	COG3711	transcriptional antiterminator
FLK61_23940	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FLK61_24015	COG2188	Transcriptional regulator
FLK61_24020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_24020	COG1263	PTS System
FLK61_24020	COG2190	(PTS) system
FLK61_24025	COG2723	6-phospho-beta-galactosidase activity
FLK61_24030	COG0717	Belongs to the dCTP deaminase family
FLK61_24035	COG0523	cobalamin synthesis protein
FLK61_24040	COG0523	cobalamin synthesis protein
FLK61_24060	COG2205	protein histidine kinase activity
FLK61_24065	COG2205	protein histidine kinase activity
FLK61_24075	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FLK61_24080	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FLK61_24095	COG4152	abc transporter atp-binding protein
FLK61_24100	COG1131	(ABC) transporter
FLK61_24130	COG0436	Aminotransferase
FLK61_24135	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FLK61_24140	COG0235	Class ii aldolase
FLK61_24145	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FLK61_24150	COG1850	ribulose-bisphosphate carboxylase activity
FLK61_24155	COG1879	ABC-type sugar transport system periplasmic component
FLK61_24160	COG1129	ABC transporter
FLK61_24165	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLK61_24175	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FLK61_24185	COG5646	InterPro IPR014922
FLK61_24210	COG0346	lactoylglutathione lyase activity
FLK61_24220	COG2130	NADP-dependent
FLK61_24230	COG1595	DNA-templated transcription, initiation
FLK61_24255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_24260	COG2207	Transcriptional regulator
FLK61_24265	COG0456	acetyltransferase
FLK61_24285	COG0456	acetyltransferase
FLK61_24325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLK61_24340	COG0702	epimerase
FLK61_24360	COG1131	(ABC) transporter
FLK61_24390	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FLK61_24395	COG1714	RDD family
FLK61_24410	COG0456	acetyltransferase
FLK61_24415	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLK61_24470	COG2814	Major facilitator Superfamily
FLK61_24495	COG0745	RESPONSE REGULATOR receiver
FLK61_24500	COG5002	protein histidine kinase activity
FLK61_24540	COG1695	Transcriptional regulator
FLK61_24560	COG2323	membrane
FLK61_24565	COG2203	Gaf domain
FLK61_24565	COG4585	Histidine kinase
FLK61_24570	COG2197	response regulator
FLK61_24580	COG5001	Diguanylate cyclase
FLK61_24580	COG4251	negative regulation of phosphorylation
FLK61_24580	COG3706	GGDEF domain
FLK61_24580	COG2203	Gaf domain
FLK61_24590	COG1846	Transcriptional regulator
FLK61_24605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_24630	COG1132	(ABC) transporter
FLK61_24640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLK61_24645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLK61_24650	COG2323	membrane
FLK61_24655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FLK61_24665	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FLK61_24700	COG0778	Nitroreductase
FLK61_24715	COG1695	Transcriptional regulator
FLK61_24725	COG1741	Belongs to the pirin family
FLK61_24745	COG0666	response to abiotic stimulus
FLK61_24775	COG1131	(ABC) transporter
FLK61_24790	COG2203	Gaf domain
FLK61_24790	COG2199	diguanylate cyclase activity
FLK61_24810	COG1064	alcohol dehydrogenase
FLK61_24820	COG1464	Belongs to the NlpA lipoprotein family
FLK61_24825	COG2011	ABC-type metal ion transport system permease component
FLK61_24830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLK61_24835	COG5583	Uncharacterized small protein (DUF2292)
FLK61_24845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLK61_24870	COG2801	Transposase and inactivated derivatives
FLK61_24885	COG2340	Cysteine-rich secretory protein family
FLK61_24905	COG3764	Sortase (surface protein transpeptidase)
FLK61_24925	COG1069	ribulokinase activity
FLK61_24935	COG1653	transport
FLK61_24940	COG1175	transmembrane transport
FLK61_24945	COG0395	ABC-type sugar transport system, permease component
FLK61_24955	COG3534	alpha-L-arabinofuranosidase
FLK61_24960	COG1609	Transcriptional regulator
FLK61_24970	COG0673	inositol 2-dehydrogenase activity
FLK61_24975	COG0747	negative chemotaxis
FLK61_24980	COG0501	Belongs to the peptidase M48B family
FLK61_24990	COG0346	lactoylglutathione lyase activity
FLK61_25000	COG2391	methyltransferase activity
FLK61_25040	COG0076	glutamate decarboxylase activity
FLK61_25045	COG0702	epimerase
FLK61_25080	COG1302	Protein conserved in bacteria
FLK61_25085	COG0840	transmembrane signaling receptor activity
FLK61_25110	COG0582	viral genome integration into host DNA
FLK61_25120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_25125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_25130	COG1120	ATPase activity
FLK61_25145	COG0488	(ABC) transporter
FLK61_25150	COG2746	aminoglycoside 3-N-acetyltransferase activity
FLK61_25170	COG0583	DNA-binding transcription factor activity
FLK61_25180	COG2226	methyltransferase
FLK61_25185	COG1854	S-ribosylhomocysteine lyase activity
FLK61_25190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLK61_25195	COG0626	cystathionine gamma-synthase activity
FLK61_25205	COG1131	(ABC) transporter
FLK61_25215	COG0584	glycerophosphoryl diester phosphodiesterase
FLK61_25220	COG3842	ATPase activity
FLK61_25225	COG1175	transmembrane transport
FLK61_25230	COG0395	ABC-type sugar transport system, permease component
FLK61_25240	COG2188	Transcriptional regulator
FLK61_25255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLK61_25260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLK61_25265	COG4152	abc transporter atp-binding protein
FLK61_25275	COG0346	lactoylglutathione lyase activity
FLK61_25280	COG0693	protein deglycase activity
FLK61_25285	COG2860	membrane
FLK61_25300	COG1272	protein, Hemolysin III
FLK61_25305	COG1295	ribonuclease BN
FLK61_25320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FLK61_25360	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLK61_25365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLK61_25370	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FLK61_25375	COG4876	unkown
FLK61_25400	COG2514	catechol 2,3-dioxygenase activity
FLK61_25405	COG1227	inorganic diphosphatase activity
FLK61_25410	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_25415	COG0765	amino acid transport
FLK61_25420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK61_25430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLK61_25435	COG0745	RESPONSE REGULATOR receiver
FLK61_25440	COG3850	Histidine kinase
FLK61_25440	COG5002	protein histidine kinase activity
FLK61_25445	COG3212	peptidase
FLK61_25450	COG3212	peptidase
FLK61_25470	COG1454	alcohol dehydrogenase
FLK61_25490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FLK61_25500	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_25525	COG2814	Major facilitator Superfamily
FLK61_25545	COG1609	Transcriptional regulator
FLK61_25555	COG0673	inositol 2-dehydrogenase activity
FLK61_25560	COG0673	inositol 2-dehydrogenase activity
FLK61_25565	COG1082	Xylose isomerase domain protein TIM barrel
FLK61_25570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_25570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLK61_25570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FLK61_25575	COG1105	Belongs to the carbohydrate kinase PfkB family
FLK61_25580	COG1349	DNA-binding transcription factor activity
FLK61_25590	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FLK61_25595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FLK61_25600	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FLK61_25605	COG1940	carbohydrate kinase activity
FLK61_25610	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_25610	COG2202	Pas domain
FLK61_25615	COG0753	catalase activity
FLK61_25640	COG0589	response to stress
FLK61_25645	COG0659	secondary active sulfate transmembrane transporter activity
FLK61_25650	COG0561	phosphatase activity
FLK61_25655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLK61_25660	COG0363	glucosamine-6-phosphate deaminase activity
FLK61_25685	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_25690	COG0840	transmembrane signaling receptor activity
FLK61_25690	COG5278	phosphoserine phosphatase activity
FLK61_25705	COG0861	Integral membrane protein TerC family
FLK61_25710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLK61_25715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_25740	COG1595	DNA-templated transcription, initiation
FLK61_25750	COG1132	(ABC) transporter
FLK61_25755	COG3829	transcription factor binding
FLK61_25760	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_25765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLK61_25770	COG0506	proline dehydrogenase activity
FLK61_25780	COG2239	Acts as a magnesium transporter
FLK61_25785	COG3842	ATPase activity
FLK61_25795	COG1178	ABC-type Fe3 transport system permease component
FLK61_25800	COG0705	Rhomboid family
FLK61_25810	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FLK61_25820	COG0864	Transcriptional regulator
FLK61_25825	COG2337	Toxic component of a toxin-antitoxin (TA) module
FLK61_25830	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_25835	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_25840	COG2172	sigma factor antagonist activity
FLK61_25845	COG2208	phosphoserine phosphatase activity
FLK61_25850	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_25855	COG2172	sigma factor antagonist activity
FLK61_25860	COG1191	sigma factor activity
FLK61_25870	COG2183	response to ionizing radiation
FLK61_25920	COG0626	cystathionine gamma-synthase activity
FLK61_25925	COG0802	atpase or kinase
FLK61_25930	COG1214	PFAM Peptidase M22, glycoprotease
FLK61_25935	COG0456	acetyltransferase
FLK61_25965	COG0488	(ABC) transporter
FLK61_25970	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FLK61_25995	COG1396	sequence-specific DNA binding
FLK61_26035	COG0305	Participates in initiation and elongation during chromosome replication
FLK61_26135	COG0582	viral genome integration into host DNA
FLK61_26215	COG0739	heme binding
FLK61_26275	COG4974	Belongs to the 'phage' integrase family
FLK61_26305	COG2814	Major facilitator Superfamily
FLK61_26315	COG1266	CAAX protease self-immunity
FLK61_26325	COG0459	protein refolding
FLK61_26340	COG0697	spore germination
FLK61_26375	COG5578	integral membrane protein
FLK61_26385	COG0395	ABC-type sugar transport system, permease component
FLK61_26395	COG2972	Histidine kinase
FLK61_26395	COG0745	RESPONSE REGULATOR receiver
FLK61_26400	COG4753	response regulator
FLK61_26400	COG2207	Transcriptional regulator
FLK61_26425	COG2207	Transcriptional regulator
FLK61_26425	COG3708	Transcriptional regulator
FLK61_26455	COG0583	DNA-binding transcription factor activity
FLK61_26480	COG1309	transcriptional regulator
FLK61_26515	COG0596	Alpha beta hydrolase
FLK61_26560	COG3708	Transcriptional regulator
FLK61_26560	COG2207	Transcriptional regulator
FLK61_26595	COG0604	alcohol dehydrogenase
FLK61_26610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLK61_26620	COG1473	amidohydrolase
FLK61_26625	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FLK61_26640	COG3328	transposase activity
FLK61_26650	COG2409	Drug exporters of the RND superfamily
FLK61_26670	COG0492	ferredoxin-NADP+ reductase activity
FLK61_26685	COG4585	Histidine kinase
FLK61_26690	COG2197	response regulator
FLK61_26695	COG1131	(ABC) transporter
FLK61_26710	COG2357	RelA SpoT domain protein
FLK61_26715	COG0662	Cupin 2, conserved barrel domain protein
FLK61_26725	COG3706	GGDEF domain
FLK61_26730	COG1181	Belongs to the D-alanine--D-alanine ligase family
FLK61_26735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FLK61_26745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_26745	COG1263	PTS System
FLK61_26745	COG2190	(PTS) system
FLK61_26750	COG2723	6-phospho-beta-galactosidase activity
FLK61_26755	COG2723	6-phospho-beta-galactosidase activity
FLK61_26760	COG3711	transcriptional antiterminator
FLK61_26765	COG0194	GDP metabolic process
FLK61_26770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FLK61_26780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FLK61_26790	COG0840	transmembrane signaling receptor activity
FLK61_26805	COG0791	NLP P60 protein
FLK61_26805	COG1388	LysM domain
FLK61_26810	COG0784	Response regulator, receiver
FLK61_26810	COG2198	Histidine kinase
FLK61_26810	COG5002	protein histidine kinase activity
FLK61_26815	COG0745	RESPONSE REGULATOR receiver
FLK61_26850	COG0500	methyltransferase
FLK61_26855	COG5002	protein histidine kinase activity
FLK61_26860	COG0596	Alpha beta hydrolase
FLK61_26870	COG0110	maltose O-acetyltransferase activity
FLK61_26885	COG2801	Transposase and inactivated derivatives
FLK61_26890	COG0737	Belongs to the 5'-nucleotidase family
FLK61_26905	COG0456	acetyltransferase
FLK61_26905	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLK61_26910	COG4988	ABC transporter
FLK61_26915	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FLK61_26925	COG1595	DNA-templated transcription, initiation
FLK61_26940	COG1131	(ABC) transporter
FLK61_26970	COG0714	Associated with various cellular activities
FLK61_26975	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
FLK61_26980	COG1305	Transglutaminase-like
FLK61_26985	COG0519	Catalyzes the synthesis of GMP from XMP
FLK61_26985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FLK61_26995	COG3655	Transcriptional regulator
FLK61_27005	COG2252	PERMEase
FLK61_27010	COG3424	synthase
FLK61_27015	COG1755	Isoprenylcysteine carboxyl methyltransferase
FLK61_27035	COG4946	Tricorn protease homolog
FLK61_27035	COG1506	peptidase
FLK61_27035	COG0823	Involved in the tonB-independent uptake of proteins
FLK61_27045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLK61_27050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLK61_27055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLK61_27060	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FLK61_27065	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLK61_27070	COG0047	phosphoribosylformylglycinamidine synthase activity
FLK61_27075	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLK61_27080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLK61_27085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FLK61_27090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLK61_27100	COG0151	Belongs to the GarS family
FLK61_27105	COG0405	Gamma-glutamyltransferase
FLK61_27110	COG1181	Belongs to the D-alanine--D-alanine ligase family
FLK61_27125	COG4721	ABC-type cobalt transport system, permease component
FLK61_27130	COG4172	Belongs to the ABC transporter superfamily
FLK61_27135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLK61_27140	COG1253	flavin adenine dinucleotide binding
FLK61_27150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_27160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FLK61_27165	COG1470	cell adhesion involved in biofilm formation
FLK61_27170	COG4496	protein, YerC YecD
FLK61_27175	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FLK61_27180	COG0210	DNA helicase
FLK61_27185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FLK61_27190	COG4851	CamS sex pheromone cAM373 precursor
FLK61_27200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK61_27205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLK61_27210	COG0154	amidase activity
FLK61_27230	COG0714	Associated with various cellular activities
FLK61_27245	COG1597	lipid kinase activity
FLK61_27255	COG1131	(ABC) transporter
FLK61_27285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLK61_27290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FLK61_27300	COG2390	Transcriptional regulator
FLK61_27320	COG1405	negative regulation of cell septum assembly
FLK61_27320	COG3012	SEC-C Motif Domain Protein
FLK61_27325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLK61_27330	COG0667	Aldo Keto reductase
FLK61_27355	COG1361	Conserved repeat domain
FLK61_27365	COG0596	Alpha beta hydrolase
FLK61_27395	COG2808	Putative FMN-binding domain
FLK61_27425	COG1454	alcohol dehydrogenase
FLK61_27445	COG0028	Belongs to the TPP enzyme family
FLK61_27455	COG0456	acetyltransferase
FLK61_27455	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLK61_27490	COG0446	pyridine nucleotide-disulphide oxidoreductase
FLK61_27505	COG2226	methyltransferase
FLK61_27530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_27530	COG1263	PTS System
FLK61_27535	COG1621	beta-fructofuranosidase activity
FLK61_27540	COG1609	Transcriptional regulator
FLK61_27545	COG0791	NLP P60 protein
FLK61_27555	COG2176	DNA-directed DNA polymerase activity
FLK61_27575	COG1404	Belongs to the peptidase S8 family
FLK61_27590	COG1376	ErfK ybiS ycfS ynhG family protein
FLK61_27630	COG4895	conserved protein (DUF2196)
FLK61_27640	COG0840	transmembrane signaling receptor activity
FLK61_27645	COG2153	protein acetylation
FLK61_27650	COG5001	Diguanylate cyclase
FLK61_27655	COG0366	Alpha amylase catalytic
FLK61_27665	COG1132	(ABC) transporter
FLK61_27670	COG1132	(ABC) transporter
FLK61_27680	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FLK61_27685	COG0840	transmembrane signaling receptor activity
FLK61_27690	COG0352	thiamine-phosphate diphosphorylase activity
FLK61_27695	COG0351	phosphomethylpyrimidine kinase
FLK61_27700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FLK61_27705	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FLK61_27715	COG0514	ATP-dependent DNA helicase (RecQ)
FLK61_27720	COG0346	lactoylglutathione lyase activity
FLK61_27725	COG0400	carboxylic ester hydrolase activity
FLK61_27730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLK61_27735	COG4251	negative regulation of phosphorylation
FLK61_27735	COG3706	GGDEF domain
FLK61_27735	COG2203	Gaf domain
FLK61_27735	COG5001	Diguanylate cyclase
FLK61_27740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLK61_27750	COG0488	(ABC) transporter
FLK61_27765	COG0628	permease
FLK61_27770	COG1216	Glycosyl transferase, family 2
FLK61_27775	COG1597	lipid kinase activity
FLK61_27785	COG0288	reversible hydration of carbon dioxide
FLK61_27790	COG1077	Cell shape determining protein MreB Mrl
FLK61_27810	COG0534	Mate efflux family protein
FLK61_27815	COG1994	Peptidase M50
FLK61_27820	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_27840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLK61_27860	COG1254	Belongs to the acylphosphatase family
FLK61_27865	COG3835	regulator
FLK61_27870	COG2610	gluconate transmembrane transporter activity
FLK61_27875	COG1929	Belongs to the glycerate kinase type-1 family
FLK61_27895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_27900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLK61_27920	COG0477	Major facilitator Superfamily
FLK61_27930	COG0534	Mate efflux family protein
FLK61_27945	COG0535	radical SAM domain protein
FLK61_27955	COG0406	alpha-ribazole phosphatase activity
FLK61_27970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FLK61_27975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLK61_27985	COG4512	PFAM Accessory gene regulator B
FLK61_27995	COG3852	Histidine kinase
FLK61_28000	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLK61_28005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLK61_28045	COG1120	ATPase activity
FLK61_28055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_28060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_28065	COG0366	Alpha amylase catalytic
FLK61_28070	COG2188	Transcriptional regulator
FLK61_28085	COG1090	epimerase
FLK61_28090	COG2137	regulation of response to DNA damage stimulus
FLK61_28105	COG1988	membrane-bound metal-dependent
FLK61_28115	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_28135	COG2059	Chromate
FLK61_28140	COG2059	Chromate
FLK61_28145	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_28160	COG3557	Belongs to the UPF0374 family
FLK61_28165	COG1132	(ABC) transporter
FLK61_28170	COG4129	membrane
FLK61_28175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLK61_28180	COG4555	ABC transporter
FLK61_28200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLK61_28215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLK61_28220	COG3870	Protein conserved in bacteria
FLK61_28225	COG0735	belongs to the Fur family
FLK61_28260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLK61_28285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_28290	COG2766	serine protein kinase
FLK61_28300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FLK61_28305	COG2718	Belongs to the UPF0229 family
FLK61_28320	COG0702	epimerase
FLK61_28330	COG3546	catalase activity
FLK61_28335	COG4191	Histidine kinase
FLK61_28345	COG3192	ethanolamine utilization protein
FLK61_28350	COG0655	NAD(P)H dehydrogenase (quinone) activity
FLK61_28385	COG0395	ABC-type sugar transport system, permease component
FLK61_28390	COG0840	transmembrane signaling receptor activity
FLK61_28395	COG2201	protein-glutamate methylesterase activity
FLK61_28430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLK61_28430	COG3153	acetyltransferase
FLK61_28435	COG2017	converts alpha-aldose to the beta-anomer
FLK61_28440	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FLK61_28445	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FLK61_28450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLK61_28455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLK61_28460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLK61_28470	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FLK61_28475	COG0066	3-isopropylmalate dehydratase activity
FLK61_28480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FLK61_28485	COG0473	3-isopropylmalate dehydrogenase activity
FLK61_28490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLK61_28495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FLK61_28500	COG0440	acetolactate synthase activity
FLK61_28505	COG0028	Belongs to the TPP enzyme family
FLK61_28515	COG3620	sequence-specific DNA binding
FLK61_28520	COG2719	SpoVR family
FLK61_28525	COG0398	Pfam SNARE associated Golgi protein
FLK61_28545	COG0667	Aldo Keto reductase
FLK61_28555	COG1388	LysM domain
FLK61_28555	COG3584	3D domain protein
FLK61_28570	COG0024	Methionine aminopeptidase
FLK61_28580	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_28585	COG2340	Cysteine-rich secretory protein family
FLK61_28600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FLK61_28610	COG2313	pseudouridylate synthase activity
FLK61_28620	COG5609	conserved protein (DUF2294)
FLK61_28625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_28625	COG1263	PTS System
FLK61_28635	COG1131	(ABC) transporter
FLK61_28640	COG1725	Transcriptional regulator
FLK61_28670	COG1294	oxidase, subunit
FLK61_28675	COG1271	oxidase subunit
FLK61_28680	COG2197	response regulator
FLK61_28685	COG1132	(ABC) transporter
FLK61_28690	COG1132	(ABC) transporter
FLK61_28700	COG0702	epimerase
FLK61_28705	COG1960	acyl-CoA dehydrogenase activity
FLK61_28710	COG0439	Biotin carboxylase
FLK61_28715	COG0511	ligase activity, forming carbon-carbon bonds
FLK61_28720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLK61_28725	COG1024	Enoyl-CoA hydratase
FLK61_28730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FLK61_28735	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLK61_28750	COG3842	ATPase activity
FLK61_28755	COG2508	Transcriptional regulator
FLK61_28765	COG4399	Belongs to the UPF0754 family
FLK61_28775	COG0561	phosphatase activity
FLK61_28790	COG0420	3'-5' exonuclease activity
FLK61_28795	COG4717	serine-type aminopeptidase activity
FLK61_28800	COG0745	RESPONSE REGULATOR receiver
FLK61_28805	COG2770	Histidine kinase
FLK61_28805	COG2205	protein histidine kinase activity
FLK61_28810	COG3481	metal-dependent phosphohydrolase, HD sub domain
FLK61_28820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FLK61_28850	COG1846	Transcriptional regulator
FLK61_28855	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FLK61_28860	COG0537	adenosine 5'-monophosphoramidase activity
FLK61_28865	COG1131	(ABC) transporter
FLK61_28870	COG4473	ABC transporter
FLK61_28875	COG1473	amidohydrolase
FLK61_28880	COG0785	Cytochrome C biogenesis protein
FLK61_28885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_28890	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FLK61_28905	COG0010	Belongs to the arginase family
FLK61_28915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FLK61_28920	COG4492	Belongs to the UPF0735 family
FLK61_28925	COG0077	Prephenate dehydratase
FLK61_28940	COG0217	transcriptional regulatory protein
FLK61_28950	COG0632	four-way junction helicase activity
FLK61_28970	COG0343	queuine tRNA-ribosyltransferase activity
FLK61_28975	COG1862	Preprotein translocase
FLK61_28990	COG2323	membrane
FLK61_28995	COG2244	polysaccharide biosynthetic process
FLK61_29010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK61_29010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK61_29015	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK61_29015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLK61_29020	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLK61_29025	COG5416	Lipopolysaccharide assembly protein A domain
FLK61_29030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FLK61_29030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FLK61_29035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLK61_29040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLK61_29045	COG1490	D-aminoacyl-tRNA deacylase activity
FLK61_29050	COG0124	histidyl-tRNA synthetase
FLK61_29055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FLK61_29070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FLK61_29075	COG2364	Membrane
FLK61_29080	COG1959	2 iron, 2 sulfur cluster binding
FLK61_29085	COG1104	cysteine desulfurase activity
FLK61_29090	COG0482	sulfurtransferase activity
FLK61_29100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FLK61_29115	COG0628	permease
FLK61_29125	COG4472	Bacterial protein of unknown function (DUF965)
FLK61_29130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FLK61_29135	COG3906	Belongs to the UPF0473 family
FLK61_29145	COG4122	O-methyltransferase activity
FLK61_29150	COG0572	uridine kinase
FLK61_29155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FLK61_29170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLK61_29180	COG0823	Involved in the tonB-independent uptake of proteins
FLK61_29180	COG4946	Tricorn protease homolog
FLK61_29180	COG1506	peptidase
FLK61_29185	COG0803	Belongs to the bacterial solute-binding protein 9 family
FLK61_29195	COG0667	Aldo Keto reductase
FLK61_29200	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FLK61_29205	COG0656	L-ascorbic acid biosynthetic process
FLK61_29225	COG0697	spore germination
FLK61_29230	COG0095	Lipoate-protein ligase
FLK61_29245	COG0617	tRNA 3'-terminal CCA addition
FLK61_29245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FLK61_29245	COG3620	sequence-specific DNA binding
FLK61_29295	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FLK61_29300	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FLK61_29310	COG1534	Rna-binding protein
FLK61_29315	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLK61_29320	COG1713	HD superfamily hydrolase involved in NAD metabolism
FLK61_29325	COG0799	negative regulation of ribosome biogenesis
FLK61_29330	COG2226	methyltransferase
FLK61_29335	COG1555	photosystem II stabilization
FLK61_29335	COG1596	polysaccharide export
FLK61_29340	COG2131	deaminase
FLK61_29345	COG2333	competence protein COMEC
FLK61_29345	COG0658	competence protein
FLK61_29355	COG1466	dna polymerase III delta subunit
FLK61_29365	COG0268	Binds directly to 16S ribosomal RNA
FLK61_29375	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_29385	COG0481	GTPase activity
FLK61_29390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FLK61_29395	COG1420	regulation of RNA biosynthetic process
FLK61_29400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FLK61_29405	COG0443	Heat shock 70 kDa protein
FLK61_29410	COG0484	heat shock protein binding
FLK61_29415	COG2264	protein methyltransferase activity
FLK61_29420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FLK61_29425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLK61_29430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FLK61_29435	COG1610	YqeY-like protein
FLK61_29445	COG1030	water channel activity
FLK61_29450	COG4864	UPF0365 protein
FLK61_29470	COG1702	phosphate starvation-inducible protein PhoH
FLK61_29475	COG1480	7TM receptor with intracellular HD hydrolase
FLK61_29480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FLK61_29485	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FLK61_29490	COG0295	cytidine deaminase activity
FLK61_29495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FLK61_29505	COG1381	Involved in DNA repair and RecF pathway recombination
FLK61_29510	COG0752	glycyl-tRNA synthetase alpha subunit
FLK61_29515	COG0751	glycine-tRNA ligase activity
FLK61_29520	COG0517	IMP dehydrogenase activity
FLK61_29525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FLK61_29530	COG1671	Belongs to the UPF0178 family
FLK61_29535	COG0358	DNA primase activity
FLK61_29540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLK61_29550	COG0584	glycerophosphoryl diester phosphodiesterase
FLK61_29565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLK61_29570	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FLK61_29575	COG1329	Transcriptional regulator
FLK61_29580	COG0513	Belongs to the DEAD box helicase family
FLK61_29585	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FLK61_29595	COG1121	(ABC) transporter
FLK61_29600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK61_29610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FLK61_29620	COG1121	(ABC) transporter
FLK61_29625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK61_29630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FLK61_29635	COG0735	belongs to the Fur family
FLK61_29640	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
FLK61_29645	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FLK61_29655	COG4086	secreted protein
FLK61_29675	COG1396	sequence-specific DNA binding
FLK61_29715	COG5521	maltodextrose utilization protein MalA
FLK61_29725	COG4918	Iron-sulphur cluster biosynthesis
FLK61_29730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLK61_29740	COG0768	penicillin binding
FLK61_29760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FLK61_29765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLK61_29770	COG1836	PFAM Integral membrane protein DUF92
FLK61_29785	COG0457	Tetratricopeptide repeat
FLK61_29785	COG0705	Rhomboid family
FLK61_29790	COG0697	spore germination
FLK61_29805	COG1940	carbohydrate kinase activity
FLK61_29825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_29835	COG4980	gas vesicle protein
FLK61_29840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLK61_29845	COG1459	type II secretion system
FLK61_29850	COG4537	Required for transformation and DNA binding
FLK61_29875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLK61_29890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FLK61_29895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FLK61_29900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLK61_29905	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLK61_29910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK61_29915	COG0095	Lipoate-protein ligase
FLK61_29920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLK61_29935	COG1752	Esterase of the alpha-beta hydrolase superfamily
FLK61_29955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FLK61_29960	COG0006	proline dipeptidase activity
FLK61_29965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FLK61_29970	COG3854	ATPases associated with a variety of cellular activities
FLK61_30015	COG0511	ligase activity, forming carbon-carbon bonds
FLK61_30020	COG0439	Biotin carboxylase
FLK61_30025	COG1302	Protein conserved in bacteria
FLK61_30030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLK61_30040	COG1570	exodeoxyribonuclease VII activity
FLK61_30045	COG1722	exodeoxyribonuclease VII activity
FLK61_30050	COG0142	geranyltranstransferase activity
FLK61_30060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLK61_30065	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FLK61_30070	COG1438	arginine binding
FLK61_30075	COG0497	DNA recombination
FLK61_30080	COG0750	zinc metalloprotease
FLK61_30085	COG0745	RESPONSE REGULATOR receiver
FLK61_30095	COG3829	transcription factor binding
FLK61_30095	COG3290	protein histidine kinase activity
FLK61_30100	COG0280	phosphate acetyltransferase
FLK61_30110	COG3426	butyrate kinase activity
FLK61_30115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLK61_30120	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLK61_30125	COG0022	dehydrogenase e1 component
FLK61_30130	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_30155	COG4129	membrane
FLK61_30165	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FLK61_30165	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FLK61_30170	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FLK61_30170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FLK61_30175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FLK61_30180	COG2195	Cleaves the N-terminal amino acid of tripeptides
FLK61_30190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLK61_30200	COG2257	FlhB HrpN YscU SpaS Family
FLK61_30215	COG1728	Protein conserved in bacteria
FLK61_30225	COG0517	IMP dehydrogenase activity
FLK61_30230	COG4187	Peptidase family M20/M25/M40
FLK61_30235	COG0789	Transcriptional regulator
FLK61_30245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLK61_30250	COG0300	oxidoreductase activity
FLK61_30260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLK61_30270	COG0367	asparagine synthase
FLK61_30285	COG1562	ergosterol biosynthetic process
FLK61_30310	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_30315	COG0561	phosphatase activity
FLK61_30320	COG2190	(PTS) system
FLK61_30325	COG1968	undecaprenyl-diphosphatase activity
FLK61_30335	COG0667	Aldo Keto reductase
FLK61_30340	COG0494	nUDIX hydrolase
FLK61_30345	COG1300	Membrane
FLK61_30350	COG0735	belongs to the Fur family
FLK61_30360	COG4974	Belongs to the 'phage' integrase family
FLK61_30375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FLK61_30385	COG1686	Belongs to the peptidase S11 family
FLK61_30390	COG1366	Belongs to the anti-sigma-factor antagonist family
FLK61_30395	COG2172	sigma factor antagonist activity
FLK61_30405	COG0697	spore germination
FLK61_30410	COG0019	diaminopimelate decarboxylase activity
FLK61_30415	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLK61_30420	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLK61_30420	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLK61_30425	COG0307	riboflavin synthase, alpha
FLK61_30430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLK61_30430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLK61_30435	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FLK61_30440	COG1547	Domain of unknown function (DUF309)
FLK61_30445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FLK61_30450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLK61_30455	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_30475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLK61_30485	COG1686	Belongs to the peptidase S11 family
FLK61_30490	COG2715	membrane protein required for spore maturation
FLK61_30495	COG0700	Nucleoside recognition
FLK61_30500	COG1187	pseudouridine synthase activity
FLK61_30505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_30510	COG1333	cytochrome c biogenesis protein
FLK61_30515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLK61_30520	COG0745	RESPONSE REGULATOR receiver
FLK61_30525	COG5002	protein histidine kinase activity
FLK61_30530	COG2096	Adenosyltransferase
FLK61_30540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FLK61_30545	COG1141	Ferredoxin
FLK61_30555	COG0514	ATP-dependent DNA helicase (RecQ)
FLK61_30560	COG1266	CAAX protease self-immunity
FLK61_30575	COG1408	metallophosphoesterase
FLK61_30590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FLK61_30595	COG0492	ferredoxin-NADP+ reductase activity
FLK61_30600	COG0252	asparaginase activity
FLK61_30605	COG2339	peptidase activity
FLK61_30615	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_30615	COG3773	Cell wall hydrolase
FLK61_30620	COG2959	enzyme of heme biosynthesis
FLK61_30630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FLK61_30635	COG0204	Acyl-transferase
FLK61_30645	COG1304	FMN binding
FLK61_30655	COG1160	GTP binding
FLK61_30660	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FLK61_30665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FLK61_30685	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FLK61_30695	COG0302	gtp cyclohydrolase
FLK61_30705	COG0142	geranyltranstransferase activity
FLK61_30710	COG2226	methyltransferase
FLK61_30715	COG0109	protoheme IX farnesyltransferase activity
FLK61_30720	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FLK61_30725	COG0142	geranyltranstransferase activity
FLK61_30730	COG0105	UTP biosynthetic process
FLK61_30735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FLK61_30740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FLK61_30745	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FLK61_30755	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLK61_30760	COG0134	indole-3-glycerol-phosphate synthase activity
FLK61_30765	COG0133	tryptophan synthase activity
FLK61_30770	COG0159	tryptophan synthase activity
FLK61_30775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLK61_30780	COG0287	Prephenate dehydrogenase
FLK61_30785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FLK61_30790	COG0457	Tetratricopeptide repeat
FLK61_30795	COG5582	Belongs to the UPF0302 family
FLK61_30805	COG0723	plastoquinol--plastocyanin reductase activity
FLK61_30810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLK61_30815	COG2010	Cytochrome c
FLK61_30815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FLK61_30820	COG4347	Protein of unknown function (DUF1405)
FLK61_30830	COG2738	Putative neutral zinc metallopeptidase
FLK61_30835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_30840	COG1694	Mazg nucleotide pyrophosphohydrolase
FLK61_30845	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FLK61_30850	COG1803	Methylglyoxal synthase
FLK61_30855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLK61_30860	COG0438	transferase activity, transferring glycosyl groups
FLK61_30870	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FLK61_30870	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FLK61_30875	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FLK61_30880	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FLK61_30885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FLK61_30890	COG1199	ATP-dependent helicase activity
FLK61_30890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FLK61_30895	COG0402	S-adenosylhomocysteine deaminase activity
FLK61_30915	COG0017	Asparaginyl-tRNA synthetase
FLK61_30920	COG3935	DnaD domain protein
FLK61_30925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLK61_30935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_30935	COG4499	WXG100 protein secretion system (Wss), protein YukC
FLK61_30940	COG3331	DNA recombination
FLK61_30965	COG1335	isochorismatase
FLK61_30975	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FLK61_30980	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FLK61_30985	COG0492	ferredoxin-NADP+ reductase activity
FLK61_30985	COG3118	belongs to the thioredoxin family
FLK61_30995	COG1413	lyase activity
FLK61_31005	COG3402	PFAM membrane-flanked domain
FLK61_31010	COG3428	Bacterial PH domain
FLK61_31020	COG1191	sigma factor activity
FLK61_31055	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLK61_31060	COG0805	protein transport
FLK61_31065	COG1428	Deoxynucleoside kinase
FLK61_31070	COG1428	Deoxynucleoside kinase
FLK61_31080	COG4667	esterase of the alpha-beta hydrolase superfamily
FLK61_31085	COG2814	Major facilitator Superfamily
FLK61_31100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLK61_31105	COG0114	fumarate hydratase activity
FLK61_31115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_31120	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_31135	COG0436	Aminotransferase
FLK61_31140	COG0567	Dehydrogenase, E1 component
FLK61_31145	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_31155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_31160	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FLK61_31180	COG0205	6-phosphofructokinase activity
FLK61_31185	COG0671	phosphoesterase, PA-phosphatase related
FLK61_31190	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FLK61_31200	COG1183	phosphatidylcholine synthase activity
FLK61_31205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLK61_31210	COG0628	permease
FLK61_31215	COG1295	ribonuclease BN
FLK61_31220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLK61_31225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLK61_31230	COG0398	Pfam SNARE associated Golgi protein
FLK61_31240	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FLK61_31245	COG1074	ATP-dependent DNA helicase activity
FLK61_31250	COG0420	3'-5' exonuclease activity
FLK61_31255	COG0419	ATPase involved in DNA repair
FLK61_31265	COG2011	ABC-type metal ion transport system permease component
FLK61_31270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLK61_31280	COG1960	acyl-CoA dehydrogenase activity
FLK61_31285	COG0488	(ABC) transporter
FLK61_31310	COG0523	cobalamin synthesis protein
FLK61_31335	COG2267	carboxylic ester hydrolase activity
FLK61_31340	COG1764	response to oxidative stress
FLK61_31360	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_31360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_31365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_31375	COG0346	lactoylglutathione lyase activity
FLK61_31380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLK61_31420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLK61_31425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FLK61_31430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FLK61_31435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FLK61_31440	COG0505	Belongs to the CarA family
FLK61_31450	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FLK61_31455	COG0137	argininosuccinate synthase activity
FLK61_31460	COG0165	Argininosuccinate lyase
FLK61_31465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FLK61_31470	COG3209	COG3209 Rhs family protein
FLK61_31515	COG3209	COG3209 Rhs family protein
FLK61_31530	COG4637	Psort location Cytoplasmic, score
FLK61_31540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK61_31550	COG3011	Protein conserved in bacteria
FLK61_31555	COG0456	acetyltransferase
FLK61_31570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FLK61_31575	COG0582	viral genome integration into host DNA
FLK61_31580	COG3180	Ammonia monooxygenase
FLK61_31585	COG1917	Cupin 2, conserved barrel domain protein
FLK61_31590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLK61_31595	COG0456	acetyltransferase
FLK61_31615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLK61_31630	COG3830	Belongs to the UPF0237 family
FLK61_31640	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FLK61_31650	COG0004	ammonium transporteR
FLK61_31670	COG4221	oxidoreductase activity
FLK61_31675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLK61_31680	COG2996	Protein conserved in bacteria
FLK61_31685	COG0551	DNA topoisomerase type I activity
FLK61_31685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLK61_31690	COG1408	metallophosphoesterase
FLK61_31710	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_31720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FLK61_31730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FLK61_31740	COG0561	phosphatase activity
FLK61_31765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLK61_31780	COG0577	efflux transmembrane transporter activity
FLK61_31785	COG1136	(ABC) transporter
FLK61_31790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLK61_31795	COG0187	DNA topoisomerase II activity
FLK61_31800	COG1832	CoA-binding protein
FLK61_31810	COG1174	glycine betaine transport
FLK61_31820	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FLK61_31835	COG0116	Belongs to the methyltransferase superfamily
FLK61_31845	COG0328	RNA-DNA hybrid ribonuclease activity
FLK61_31850	COG3599	regulation of cell shape
FLK61_31875	COG3359	exonuclease
FLK61_31880	COG1205	dead DEAH box helicase
FLK61_31880	COG1111	helicase
FLK61_31885	COG1331	Highly conserved protein containing a thioredoxin domain
FLK61_31900	COG2267	carboxylic ester hydrolase activity
FLK61_31905	COG0693	protein deglycase activity
FLK61_31910	COG1418	mRNA catabolic process
FLK61_31920	COG0835	chemotaxis
FLK61_31920	COG0784	Response regulator, receiver
FLK61_31935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLK61_31975	COG2200	EAL domain
FLK61_31980	COG0613	PHP domain protein
FLK61_31985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FLK61_31995	COG0824	Thioesterase
FLK61_32000	COG0464	growth
FLK61_32005	COG0398	Pfam SNARE associated Golgi protein
FLK61_32015	COG2323	membrane
FLK61_32020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLK61_32025	COG1921	L-seryl-tRNASec selenium transferase activity
FLK61_32050	COG4846	Membrane protein involved in cytochrome C biogenesis
FLK61_32070	COG1937	Protein conserved in bacteria
FLK61_32075	COG1132	(ABC) transporter
FLK61_32080	COG1132	(ABC) transporter
FLK61_32085	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FLK61_32090	COG3763	UPF0154 protein
FLK61_32100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FLK61_32105	COG4224	UPF0291 protein
FLK61_32110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FLK61_32120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLK61_32130	COG0174	glutamine synthetase
FLK61_32135	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FLK61_32145	COG0464	growth
FLK61_32150	COG1923	regulation of RNA biosynthetic process
FLK61_32155	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FLK61_32160	COG2136	Putative SAM-dependent methyltransferase
FLK61_32160	COG2521	methyltransferase
FLK61_32165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FLK61_32170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FLK61_32180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FLK61_32185	COG4550	Control of competence regulator ComK, YlbF/YmcA
FLK61_32190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLK61_32195	COG0156	8-amino-7-oxononanoate synthase activity
FLK61_32200	COG1063	alcohol dehydrogenase
FLK61_32205	COG2359	stage V sporulation protein S
FLK61_32210	COG1692	metallophosphoesterase
FLK61_32215	COG1418	mRNA catabolic process
FLK61_32220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FLK61_32225	COG0513	Belongs to the DEAD box helicase family
FLK61_32230	COG1546	Belongs to the CinA family
FLK61_32230	COG1058	Belongs to the CinA family
FLK61_32235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLK61_32240	COG1426	Protein conserved in bacteria
FLK61_32255	COG0300	oxidoreductase activity
FLK61_32260	COG0612	Peptidase, M16
FLK61_32265	COG0612	Peptidase, M16
FLK61_32270	COG2188	Transcriptional regulator
FLK61_32275	COG1674	ftsk spoiiie
FLK61_32280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLK61_32290	COG0527	aspartate kinase activity
FLK61_32295	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLK61_32300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLK61_32305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLK61_32310	COG1873	PFAM PRC-barrel domain
FLK61_32315	COG0612	Peptidase, M16
FLK61_32320	COG0726	polysaccharide deacetylase
FLK61_32325	COG1185	polyribonucleotide nucleotidyltransferase activity
FLK61_32330	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FLK61_32335	COG0196	riboflavin kinase activity
FLK61_32340	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLK61_32345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FLK61_32355	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLK61_32360	COG1358	cellular component organization or biogenesis
FLK61_32365	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FLK61_32370	COG0195	Participates in both transcription termination and antitermination
FLK61_32375	COG0779	Required for maturation of 30S ribosomal subunits
FLK61_32380	COG2176	DNA-directed DNA polymerase activity
FLK61_32385	COG0442	prolyl-tRNA aminoacylation
FLK61_32390	COG0750	zinc metalloprotease
FLK61_32400	COG4589	Belongs to the CDS family
FLK61_32405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLK61_32410	COG0233	cytoplasmic translational termination
FLK61_32415	COG0528	UMP kinase activity
FLK61_32420	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FLK61_32425	COG0052	Belongs to the universal ribosomal protein uS2 family
FLK61_32445	COG1191	sigma factor activity
FLK61_32455	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FLK61_32460	COG1776	CheC inhibitor of MCP methylation
FLK61_32465	COG0835	chemotaxis
FLK61_32470	COG0643	Histidine kinase
FLK61_32470	COG2198	Histidine kinase
FLK61_32475	COG2201	protein-glutamate methylesterase activity
FLK61_32480	COG0455	bacterial-type flagellum organization
FLK61_32485	COG1419	protein localization to endoplasmic reticulum
FLK61_32490	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLK61_32495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLK61_32500	COG1684	flagellar biosynthetic protein fliR
FLK61_32505	COG1987	bacterial-type flagellum assembly
FLK61_32510	COG1338	Plays a role in the flagellum-specific transport system
FLK61_32515	COG3190	flagellar
FLK61_32520	COG2201	protein-glutamate methylesterase activity
FLK61_32525	COG1776	CheC inhibitor of MCP methylation
FLK61_32525	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLK61_32530	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLK61_32535	COG1580	Controls the rotational direction of flagella during chemotaxis
FLK61_32540	COG1582	Flagellar protein (FlbD)
FLK61_32545	COG4786	Flagellar basal body rod
FLK61_32555	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FLK61_32575	COG1157	protein secretion by the type III secretion system
FLK61_32580	COG1317	bacterial-type flagellum organization
FLK61_32585	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLK61_32590	COG1766	The M ring may be actively involved in energy transduction
FLK61_32595	COG1677	Flagellar hook-basal body complex protein FliE
FLK61_32600	COG1558	bacterial-type flagellum-dependent cell motility
FLK61_32605	COG1815	bacterial-type flagellum-dependent cell motility
FLK61_32610	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FLK61_32615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FLK61_32620	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FLK61_32625	COG4974	Belongs to the 'phage' integrase family
FLK61_32630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLK61_32635	COG0758	DNA mediated transformation
FLK61_32640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FLK61_32645	COG0045	succinate-CoA ligase (ADP-forming) activity
FLK61_32650	COG2257	FlhB HrpN YscU SpaS Family
FLK61_32660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLK61_32675	COG0335	large ribosomal subunit rRNA binding
FLK61_32680	COG0336	Belongs to the RNA methyltransferase TrmD family
FLK61_32685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FLK61_32695	COG1837	Belongs to the UPF0109 family
FLK61_32700	COG0228	four-way junction DNA binding
FLK61_32705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLK61_32715	COG0552	protein localization to endoplasmic reticulum
FLK61_32720	COG1196	nuclear chromosome segregation
FLK61_32725	COG4840	Belongs to the UPF0435 family
FLK61_32735	COG3328	transposase activity
FLK61_32745	COG0571	ribonuclease III activity
FLK61_32750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLK61_32755	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_32760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FLK61_32765	COG0416	fatty acid biosynthetic process
FLK61_32770	COG1349	DNA-binding transcription factor activity
FLK61_32775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLK61_32780	COG1760	l-serine dehydratase
FLK61_32785	COG1760	l-serine dehydratase
FLK61_32790	COG1307	EDD domain protein, DegV family
FLK61_32795	COG1461	Dihydroxyacetone kinase
FLK61_32800	COG1302	Protein conserved in bacteria
FLK61_32805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FLK61_32815	COG1564	THIamine pyrophosphokinase
FLK61_32820	COG3859	Proton-coupled thiamine transporter YuaJ
FLK61_32825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLK61_32830	COG1162	GTPase activity
FLK61_32835	COG0515	serine threonine protein kinase
FLK61_32835	COG2815	serine threonine protein kinase
FLK61_32840	COG0631	protein serine/threonine phosphatase activity
FLK61_32845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLK61_32845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLK61_32855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLK61_32860	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLK61_32865	COG1758	RNA polymerase activity
FLK61_32870	COG0194	GDP metabolic process
FLK61_32875	COG2052	Domain of unknown function (DUF370)
FLK61_32880	COG1561	YicC-like family, N-terminal region
FLK61_32895	COG1132	(ABC) transporter
FLK61_32900	COG1132	(ABC) transporter
FLK61_32910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FLK61_32915	COG0284	orotidine-5'-phosphate decarboxylase activity
FLK61_32920	COG0167	dihydroorotate dehydrogenase activity
FLK61_32930	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FLK61_32935	COG0505	Belongs to the CarA family
FLK61_32945	COG0540	Belongs to the ATCase OTCase family
FLK61_32955	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FLK61_32960	COG0564	pseudouridine synthase activity
FLK61_32965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLK61_32970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FLK61_32975	COG3599	regulation of cell shape
FLK61_32980	COG2302	S4 RNA-binding domain
FLK61_32985	COG0762	integral membrane protein
FLK61_32990	COG1799	cell septum assembly
FLK61_32995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FLK61_33000	COG1873	PFAM PRC-barrel domain
FLK61_33005	COG1191	sigma factor activity
FLK61_33010	COG1191	sigma factor activity
FLK61_33025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLK61_33030	COG0849	cell division
FLK61_33035	COG3856	small basic protein
FLK61_33040	COG3879	Bacterial protein of unknown function (DUF881)
FLK61_33045	COG3879	Bacterial protein of unknown function (DUF881)
FLK61_33050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FLK61_33060	COG0772	Belongs to the SEDS family
FLK61_33065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLK61_33070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLK61_33080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLK61_33085	COG0768	penicillin binding
FLK61_33100	COG0275	rRNA processing
FLK61_33105	COG2001	Belongs to the MraZ family
FLK61_33110	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FLK61_33120	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLK61_33125	COG0454	-acetyltransferase
FLK61_33130	COG1024	Enoyl-CoA hydratase
FLK61_33135	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FLK61_33140	COG1399	metal-binding, possibly nucleic acid-binding protein
FLK61_33145	COG1323	Belongs to the UPF0348 family
FLK61_33150	COG3480	Lon protease (S16) C-terminal proteolytic domain
FLK61_33155	COG3314	Sporulation integral membrane protein YlbJ
FLK61_33160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FLK61_33165	COG0742	ribosomal rna small subunit methyltransferase
FLK61_33170	COG4471	UPF0298 protein
FLK61_33175	COG3679	Belongs to the UPF0342 family
FLK61_33190	COG2340	Cysteine-rich secretory protein family
FLK61_33195	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FLK61_33225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLK61_33240	COG1612	heme a metabolic process
FLK61_33245	COG0783	Belongs to the Dps family
FLK61_33250	COG4838	Belongs to the UPF0358 family
FLK61_33255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FLK61_33260	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FLK61_33270	COG4896	Protein conserved in bacteria
FLK61_33285	COG0483	inositol monophosphate 1-phosphatase activity
FLK61_33295	COG4493	Belongs to the UPF0637 family
FLK61_33300	COG4476	Belongs to the UPF0223 family
FLK61_33305	COG1982	Orn Lys Arg decarboxylase major
FLK61_33325	COG0726	polysaccharide deacetylase
FLK61_33340	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_33345	COG0022	dehydrogenase e1 component
FLK61_33375	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLK61_33380	COG0569	domain protein
FLK61_33385	COG0668	transmembrane transport
FLK61_33395	COG1473	amidohydrolase
FLK61_33400	COG2171	N-acyltransferase activity
FLK61_33410	COG0668	transmembrane transport
FLK61_33415	COG1132	(ABC) transporter
FLK61_33430	COG0778	Nitroreductase
FLK61_33445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FLK61_33475	COG1278	Cold shock
FLK61_33480	COG4989	oxidoreductase activity
FLK61_33490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLK61_33520	COG0604	alcohol dehydrogenase
FLK61_33525	COG2839	Protein conserved in bacteria
FLK61_33540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLK61_33545	COG0747	negative chemotaxis
FLK61_33560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
FLK61_33570	COG0602	queuosine metabolic process
FLK61_33575	COG0720	synthase
FLK61_33580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FLK61_33595	COG0425	Belongs to the sulfur carrier protein TusA family
FLK61_33600	COG0425	Belongs to the sulfur carrier protein TusA family
FLK61_33600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK61_33605	COG2210	Belongs to the sulfur carrier protein TusA family
FLK61_33610	COG1937	Protein conserved in bacteria
FLK61_33630	COG2962	Rard protein
FLK61_33655	COG1131	(ABC) transporter
FLK61_33660	COG2188	Transcriptional regulator
FLK61_33675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FLK61_33710	COG0431	NADPH-dependent FMN reductase
FLK61_33710	COG3976	FMN-binding domain protein
FLK61_33710	COG1053	succinate dehydrogenase
FLK61_33970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLK61_34025	COG4974	Belongs to the 'phage' integrase family
FLK61_34265	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLK61_34320	COG4974	Belongs to the 'phage' integrase family
FLK61_34325	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FLK61_34330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FLK61_34335	COG0564	pseudouridine synthase activity
FLK61_34340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLK61_34345	COG2357	RelA SpoT domain protein
FLK61_34350	COG4116	CYTH
FLK61_34355	COG0741	lytic transglycosylase activity
FLK61_34360	COG2346	COG2346, Truncated hemoglobins
FLK61_34370	COG1164	Oligoendopeptidase f
FLK61_34385	COG0861	Integral membrane protein TerC family
FLK61_34390	COG1393	Belongs to the ArsC family
FLK61_34395	COG0456	acetyltransferase
FLK61_34405	COG1418	mRNA catabolic process
FLK61_34420	COG1522	sequence-specific DNA binding
FLK61_34425	COG1301	dicarboxylic acid transport
FLK61_34430	COG0180	Tryptophanyl-tRNA synthetase
FLK61_34445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FLK61_34450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLK61_34465	COG1744	ABC transporter substrate-binding protein PnrA-like
FLK61_34475	COG4841	protein insertion into membrane
FLK61_34480	COG1999	signal sequence binding
FLK61_34485	COG3336	cytochrome c oxidase
FLK61_34500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FLK61_34515	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FLK61_34520	COG1461	Dihydroxyacetone kinase
FLK61_34525	COG2376	Dihydroxyacetone kinase
FLK61_34545	COG0747	negative chemotaxis
FLK61_34550	COG1609	Transcriptional regulator
FLK61_34555	COG3833	ABC-type maltose transport systems, permease component
FLK61_34560	COG1175	transmembrane transport
FLK61_34565	COG2182	Extracellular solute-binding protein
FLK61_34570	COG0840	transmembrane signaling receptor activity
FLK61_34575	COG1917	Cupin 2, conserved barrel domain protein
FLK61_34575	COG2207	Transcriptional regulator
FLK61_34580	COG0534	Mate efflux family protein
FLK61_34585	COG2358	TRAP transporter, solute receptor (TAXI family
FLK61_34600	COG1509	lysine 2,3-aminomutase activity
FLK61_34615	COG2249	NAD(P)H dehydrogenase (quinone) activity
FLK61_34620	COG2203	Gaf domain
FLK61_34620	COG4251	negative regulation of phosphorylation
FLK61_34620	COG5001	Diguanylate cyclase
FLK61_34620	COG3706	GGDEF domain
FLK61_34625	COG2154	pterin-4-alpha-carbinolamine dehydratase
FLK61_34635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLK61_34640	COG0640	Transcriptional regulator
FLK61_34675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLK61_34700	COG0686	Belongs to the AlaDH PNT family
FLK61_34710	COG2801	Transposase and inactivated derivatives
FLK61_34725	COG0745	RESPONSE REGULATOR receiver
FLK61_34730	COG0704	Plays a role in the regulation of phosphate uptake
FLK61_34735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FLK61_34740	COG0581	inorganic phosphate transmembrane transporter activity
FLK61_34745	COG0573	inorganic phosphate transmembrane transporter activity
FLK61_34750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FLK61_34760	COG1234	tRNA 3'-trailer cleavage
FLK61_34765	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FLK61_34770	COG2868	ribosomal protein
FLK61_34775	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FLK61_34780	COG1530	ribonuclease E activity
FLK61_34805	COG1609	Transcriptional regulator
FLK61_34810	COG1653	transport
FLK61_34815	COG2894	cell division
FLK61_34820	COG0850	regulation of cytokinetic process
FLK61_34825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FLK61_34830	COG1792	Involved in formation and maintenance of cell shape
FLK61_34835	COG1077	Cell shape determining protein MreB Mrl
FLK61_34845	COG2003	Belongs to the UPF0758 family
FLK61_34855	COG2003	Belongs to the UPF0758 family
FLK61_34860	COG0424	maF-like protein
FLK61_34885	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FLK61_34895	COG1459	type II secretion system
FLK61_34905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLK61_34920	COG0285	dihydrofolate synthase activity
FLK61_34930	COG0189	ligase activity
FLK61_34935	COG2197	response regulator
FLK61_34960	COG2252	PERMEase
FLK61_34965	COG0525	valine-tRNA ligase activity
FLK61_34975	COG1388	LysM domain
FLK61_35000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FLK61_35005	COG0113	porphobilinogen synthase activity
FLK61_35015	COG0181	hydroxymethylbilane synthase activity
FLK61_35020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FLK61_35025	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FLK61_35030	COG1126	abc transporter atp-binding protein
FLK61_35035	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FLK61_35040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FLK61_35045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLK61_35050	COG0544	peptidyl-prolyl cis-trans isomerase activity
FLK61_35055	COG1477	protein flavinylation
FLK61_35055	COG0457	Tetratricopeptide repeat
FLK61_35075	COG4824	toxin secretion phage lysis holin
FLK61_35220	COG0582	viral genome integration into host DNA
FLK61_35280	COG0305	Participates in initiation and elongation during chromosome replication
FLK61_35330	COG1396	sequence-specific DNA binding
FLK61_35350	COG4974	Belongs to the 'phage' integrase family
FLK61_35465	COG0622	Phosphoesterase
FLK61_35470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLK61_35475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FLK61_35480	COG5401	PFAM Sporulation and spore germination
FLK61_35500	COG1846	Transcriptional regulator
FLK61_35510	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_35515	COG3711	transcriptional antiterminator
FLK61_35520	COG2197	response regulator
FLK61_35530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FLK61_35535	COG1053	succinate dehydrogenase
FLK61_35540	COG2009	succinate dehydrogenase
FLK61_35545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLK61_35565	COG0322	excinuclease ABC activity
FLK61_35570	COG3118	belongs to the thioredoxin family
FLK61_35575	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FLK61_35580	COG2086	electron transfer activity
FLK61_35585	COG1024	Enoyl-CoA hydratase
FLK61_35590	COG1309	transcriptional regulator
FLK61_35595	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_35600	COG0318	PFAM AMP-dependent synthetase and ligase
FLK61_35625	COG3766	membrane
FLK61_35630	COG1193	negative regulation of DNA recombination
FLK61_35635	COG1796	DNA polymerase
FLK61_35635	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FLK61_35640	COG1286	toxin biosynthetic process
FLK61_35645	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FLK61_35650	COG0135	phosphoribosylanthranilate isomerase activity
FLK61_35655	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLK61_35665	COG0072	phenylalanine-tRNA ligase activity
FLK61_35665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLK61_35670	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FLK61_35675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLK61_35685	COG1363	Peptidase, m42
FLK61_35690	COG0756	dUTP diphosphatase activity
FLK61_35710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FLK61_35715	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FLK61_35720	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FLK61_35730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLK61_35740	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FLK61_35745	COG1484	DNA-dependent DNA replication
FLK61_35750	COG3611	Membrane attachment protein
FLK61_35755	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FLK61_35765	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FLK61_35770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLK61_35780	COG1971	Probably functions as a manganese efflux pump
FLK61_35785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FLK61_35790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK61_35790	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLK61_35795	COG5002	protein histidine kinase activity
FLK61_35800	COG0745	RESPONSE REGULATOR receiver
FLK61_35810	COG0039	L-malate dehydrogenase activity
FLK61_35815	COG0538	isocitrate dehydrogenase activity
FLK61_35820	COG0372	Belongs to the citrate synthase family
FLK61_35825	COG2707	UPF0756 membrane protein
FLK61_35830	COG3030	protein affecting phage T7 exclusion by the F plasmid
FLK61_35840	COG0205	6-phosphofructokinase activity
FLK61_35845	COG0825	malonyl-CoA metabolic process
FLK61_35850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FLK61_35855	COG2186	Transcriptional regulator
FLK61_35860	COG0281	malic enzyme
FLK61_35865	COG0587	DNA-directed DNA polymerase activity
FLK61_35880	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FLK61_35890	COG4109	DRTGG domain
FLK61_35900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FLK61_35905	COG0006	proline dipeptidase activity
FLK61_35915	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_35935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLK61_35940	COG0827	DNA restriction-modification system
FLK61_35950	COG3874	Sporulation protein YtfJ
FLK61_35960	COG1714	RDD family
FLK61_35965	COG0616	signal peptide processing
FLK61_35970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLK61_35975	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FLK61_35985	COG1104	cysteine desulfurase activity
FLK61_35995	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FLK61_36000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FLK61_36005	COG1309	transcriptional regulator
FLK61_36010	COG1956	GAF domain-containing protein
FLK61_36015	COG2203	Gaf domain
FLK61_36015	COG2199	diguanylate cyclase activity
FLK61_36020	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FLK61_36040	COG0454	-acetyltransferase
FLK61_36045	COG0517	IMP dehydrogenase activity
FLK61_36045	COG0516	GMP reductase activity
FLK61_36050	COG0123	including yeast histone deacetylase and acetoin utilization protein
FLK61_36055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLK61_36075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FLK61_36075	COG1605	Chorismate mutase
FLK61_36080	COG0849	cell division
FLK61_36085	COG3118	belongs to the thioredoxin family
FLK61_36090	COG4980	gas vesicle protein
FLK61_36105	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FLK61_36125	COG1674	ftsk spoiiie
FLK61_36130	COG4848	Belongs to the UPF0354 family
FLK61_36135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FLK61_36155	COG1363	Peptidase, m42
FLK61_36165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_36170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FLK61_36175	COG0510	thiamine kinase activity
FLK61_36180	COG1523	belongs to the glycosyl hydrolase 13 family
FLK61_36185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FLK61_36190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLK61_36195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLK61_36200	COG0297	glycogen (starch) synthase activity
FLK61_36205	COG0058	SHG alpha-glucan phosphorylase activity
FLK61_36220	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FLK61_36225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FLK61_36235	COG1349	DNA-binding transcription factor activity
FLK61_36240	COG1187	pseudouridine synthase activity
FLK61_36245	COG0772	Belongs to the SEDS family
FLK61_36260	COG1733	regulation of RNA biosynthetic process
FLK61_36265	COG2244	polysaccharide biosynthetic process
FLK61_36270	COG0432	Pfam Uncharacterised protein family UPF0047
FLK61_36275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLK61_36285	COG2081	HI0933 family
FLK61_36290	COG0495	leucyl-tRNA aminoacylation
FLK61_36295	COG2814	Major facilitator Superfamily
FLK61_36305	COG1242	4 iron, 4 sulfur cluster binding
FLK61_36310	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FLK61_36315	COG2267	carboxylic ester hydrolase activity
FLK61_36320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLK61_36325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FLK61_36330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FLK61_36335	COG1116	anion transmembrane transporter activity
FLK61_36340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLK61_36345	COG0494	nUDIX hydrolase
FLK61_36350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLK61_36360	COG0840	transmembrane signaling receptor activity
FLK61_36360	COG5278	phosphoserine phosphatase activity
FLK61_36375	COG1011	Hydrolase
FLK61_36380	COG2133	pyrroloquinoline quinone binding
FLK61_36390	COG2184	nucleotidyltransferase activity
FLK61_36410	COG3186	Phenylalanine-4-hydroxylase
FLK61_36420	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_36435	COG0006	proline dipeptidase activity
FLK61_36440	COG0402	S-adenosylhomocysteine deaminase activity
FLK61_36445	COG2508	Transcriptional regulator
FLK61_36450	COG0733	neurotransmitter:sodium symporter activity
FLK61_36455	COG0179	Fumarylacetoacetate (FAA) hydrolase
FLK61_36470	COG0671	phosphoesterase, PA-phosphatase related
FLK61_36505	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FLK61_36515	COG0166	Belongs to the GPI family
FLK61_36520	COG1979	alcohol dehydrogenase
FLK61_36525	COG2155	Conserved Protein
FLK61_36530	COG1098	S1 RNA binding domain
FLK61_36535	COG0436	Aminotransferase
FLK61_36540	COG1522	sequence-specific DNA binding
FLK61_36550	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_36620	COG2056	Na+-H+ antiporter family
FLK61_36625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FLK61_36630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FLK61_36640	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FLK61_36655	COG1252	NADH dehydrogenase
FLK61_36670	COG0316	Belongs to the HesB IscA family
FLK61_36675	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FLK61_36685	COG4844	belongs to the
FLK61_36690	COG1252	NADH dehydrogenase
FLK61_36695	COG4837	Protein of unknown function (DUF1462)
FLK61_36700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FLK61_36705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLK61_36715	COG0647	UMP catabolic process
FLK61_36720	COG2445	Protein of unknown function DUF86
FLK61_36725	COG1494	fructose-1,6-bisphosphatase
FLK61_36735	COG4470	Protein conserved in bacteria
FLK61_36745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FLK61_36750	COG0739	heme binding
FLK61_36755	COG0733	neurotransmitter:sodium symporter activity
FLK61_36760	COG1757	Na H antiporter
FLK61_36770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLK61_36785	COG0737	Belongs to the 5'-nucleotidase family
FLK61_36790	COG0730	response to heat
FLK61_36795	COG1801	Protein of unknown function DUF72
FLK61_36800	COG3546	catalase activity
FLK61_36815	COG0719	Fe-S assembly protein
FLK61_36820	COG0822	iron-sulfur transferase activity
FLK61_36825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLK61_36830	COG0719	Fe-S assembly protein
FLK61_36835	COG0396	ATPase activity
FLK61_36845	COG1464	Belongs to the NlpA lipoprotein family
FLK61_36850	COG2011	ABC-type metal ion transport system permease component
FLK61_36855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLK61_36865	COG0509	glycine decarboxylation via glycine cleavage system
FLK61_36870	COG1393	Belongs to the ArsC family
FLK61_36880	COG1960	acyl-CoA dehydrogenase activity
FLK61_36885	COG0183	Belongs to the thiolase family
FLK61_36890	COG1024	Enoyl-CoA hydratase
FLK61_36890	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLK61_36900	COG5577	PFAM Coat F domain
FLK61_36905	COG0201	protein transport
FLK61_36920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FLK61_36930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FLK61_36945	COG0129	dihydroxy-acid dehydratase activity
FLK61_36955	COG2116	formate transmembrane transporter activity
FLK61_36975	COG0557	exoribonuclease II activity
FLK61_36980	COG1647	Serine aminopeptidase, S33
FLK61_36990	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FLK61_36995	COG0673	inositol 2-dehydrogenase activity
FLK61_37005	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FLK61_37010	COG0148	phosphopyruvate hydratase activity
FLK61_37015	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FLK61_37030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FLK61_37045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FLK61_37050	COG0740	serine-type endopeptidase activity
FLK61_37055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_37060	COG1481	regulation of sporulation
FLK61_37065	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FLK61_37070	COG1660	Displays ATPase and GTPase activities
FLK61_37075	COG1051	belongs to the nudix hydrolase family
FLK61_37080	COG0492	ferredoxin-NADP+ reductase activity
FLK61_37105	COG0140	phosphoribosyl-ATP diphosphatase activity
FLK61_37105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FLK61_37110	COG0107	imidazoleglycerol-phosphate synthase activity
FLK61_37115	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FLK61_37120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLK61_37125	COG0131	Imidazoleglycerol-phosphate dehydratase
FLK61_37130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FLK61_37135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FLK61_37140	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FLK61_37150	COG0110	maltose O-acetyltransferase activity
FLK61_37155	COG0546	phosphoglycolate phosphatase activity
FLK61_37160	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FLK61_37165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FLK61_37170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FLK61_37180	COG1950	PFAM Membrane protein of
FLK61_37185	COG1983	PspC domain protein
FLK61_37190	COG3595	metallopeptidase activity
FLK61_37195	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FLK61_37200	COG0556	nucleotide-excision repair
FLK61_37205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_37210	COG3409	Peptidoglycan-binding domain 1 protein
FLK61_37210	COG0793	Belongs to the peptidase S41A family
FLK61_37215	COG1196	nuclear chromosome segregation
FLK61_37215	COG0741	lytic transglycosylase activity
FLK61_37215	COG0739	heme binding
FLK61_37220	COG2177	Part of the ABC transporter FtsEX involved in
FLK61_37225	COG2884	Cell division ATP-binding protein ftsE
FLK61_37235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLK61_37250	COG0653	protein targeting
FLK61_37265	COG3711	transcriptional antiterminator
FLK61_37270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FLK61_37270	COG2190	(PTS) system
FLK61_37270	COG1263	PTS System
FLK61_37290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLK61_37295	COG1278	Cold shock
FLK61_37300	COG0629	single-stranded DNA binding
FLK61_37310	COG1482	cell wall glycoprotein biosynthetic process
FLK61_37350	COG3458	cephalosporin-C deacetylase activity
FLK61_37365	COG1334	flagellar protein FlaG
FLK61_37375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FLK61_37385	COG1309	transcriptional regulator
FLK61_37390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FLK61_37425	COG3239	Fatty acid desaturase
FLK61_37490	COG3063	Type IV pilus biogenesis stability protein PilW
FLK61_37515	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLK61_37515	COG0456	acetyltransferase
FLK61_37525	COG4585	Histidine kinase
FLK61_37530	COG2197	response regulator
FLK61_37535	COG2843	Capsule synthesis protein
FLK61_37540	COG0778	Nitroreductase
FLK61_37550	COG0167	dihydroorotate dehydrogenase activity
FLK61_37555	COG0543	2 iron, 2 sulfur cluster binding
FLK61_37560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FLK61_37565	COG2508	Transcriptional regulator
FLK61_37575	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FLK61_37585	COG0737	Belongs to the 5'-nucleotidase family
FLK61_37600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLK61_37615	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FLK61_37640	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FLK61_37645	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FLK61_37655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLK61_37660	COG4786	Flagellar basal body rod
FLK61_37660	COG1256	bacterial-type flagellum assembly
FLK61_37670	COG2747	anti-sigma28 factor FlgM
FLK61_37680	COG1040	competence protein
FLK61_37685	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FLK61_37690	COG1307	EDD domain protein, DegV family
FLK61_37710	COG1739	Uncharacterized protein family UPF0029
FLK61_37720	COG2801	Transposase and inactivated derivatives
FLK61_37730	COG0395	ABC-type sugar transport system, permease component
FLK61_37740	COG1653	transport
FLK61_37745	COG5578	integral membrane protein
FLK61_37755	COG2723	6-phospho-beta-galactosidase activity
FLK61_37760	COG1940	carbohydrate kinase activity
FLK61_37770	COG3620	sequence-specific DNA binding
FLK61_37775	COG1316	TRANSCRIPTIONal
FLK61_37780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLK61_37795	COG2244	polysaccharide biosynthetic process
FLK61_37805	COG0653	protein targeting
FLK61_37815	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_37820	COG4193	domain, Protein
FLK61_37820	COG5263	repeat protein
FLK61_37865	COG2340	Cysteine-rich secretory protein family
FLK61_37875	COG5001	Diguanylate cyclase
FLK61_37880	COG1361	Conserved repeat domain
FLK61_37880	COG2911	Protein conserved in bacteria
FLK61_37880	COG3266	domain, Protein
FLK61_37890	COG0737	Belongs to the 5'-nucleotidase family
FLK61_37895	COG0737	Belongs to the 5'-nucleotidase family
FLK61_37905	COG1686	Belongs to the peptidase S11 family
FLK61_37920	COG2268	Band 7 protein
FLK61_37935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLK61_37960	COG1653	transport
FLK61_37970	COG1285	pathogenesis
FLK61_37975	COG2151	metal-sulfur cluster biosynthetic enzyme
FLK61_37980	COG3290	protein histidine kinase activity
FLK61_37980	COG0840	transmembrane signaling receptor activity
FLK61_37985	COG3361	conserved protein (COG2071)
FLK61_37990	COG0415	Belongs to the DNA photolyase family
FLK61_37995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FLK61_38005	COG2311	Membrane
FLK61_38015	COG1984	allophanate hydrolase subunit 2
FLK61_38025	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FLK61_38030	COG4191	Histidine kinase
FLK61_38035	COG1744	ABC transporter substrate-binding protein PnrA-like
FLK61_38040	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FLK61_38055	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLK61_38085	COG0326	Molecular chaperone. Has ATPase activity
FLK61_38090	COG3328	transposase activity
FLK61_38110	COG2197	response regulator
FLK61_38135	COG1309	transcriptional regulator
FLK61_38140	COG1131	(ABC) transporter
FLK61_38145	COG3559	Exporter of polyketide antibiotics
FLK61_38170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FLK61_38180	COG0022	dehydrogenase e1 component
FLK61_38180	COG0508	dehydrogenase complex catalyzes the overall conversion of
FLK61_38185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FLK61_38195	COG3730	PTS system glucitol sorbitol-specific
FLK61_38200	COG3732	PTS system glucitol sorbitol-specific
FLK61_38225	COG3443	Belongs to the bacterial solute-binding protein 9 family
FLK61_38230	COG0697	spore germination
FLK61_38240	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FLK61_38245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FLK61_38250	COG0574	Belongs to the PEP-utilizing enzyme family
FLK61_38250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLK61_38255	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FLK61_38265	COG2304	oxidoreductase activity
FLK61_38300	COG2304	oxidoreductase activity
FLK61_38365	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FLK61_38375	COG3639	organic phosphonate transmembrane transporter activity
FLK61_38380	COG0561	phosphatase activity
FLK61_38390	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FLK61_38400	COG0800	Aldolase
FLK61_38405	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_38410	COG1312	Catalyzes the dehydration of D-mannonate
FLK61_38415	COG1904	glucuronate isomerase
FLK61_38420	COG3250	beta-galactosidase activity
FLK61_38425	COG2207	Transcriptional regulator
FLK61_38425	COG4753	response regulator
FLK61_38430	COG2972	Histidine kinase
FLK61_38435	COG1653	transport
FLK61_38440	COG0395	ABC-type sugar transport system, permease component
FLK61_38445	COG1175	transmembrane transport
FLK61_38460	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FLK61_38465	COG3173	Aminoglycoside phosphotransferase
FLK61_38470	COG0840	transmembrane signaling receptor activity
FLK61_38485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLK61_38490	COG1528	Iron-storage protein
FLK61_38495	COG3250	beta-galactosidase activity
FLK61_38515	COG3275	phosphorelay sensor kinase activity
FLK61_38520	COG2207	Transcriptional regulator
FLK61_38520	COG4753	response regulator
FLK61_38525	COG3290	protein histidine kinase activity
FLK61_38525	COG0840	transmembrane signaling receptor activity
FLK61_38535	COG0281	malic enzyme
FLK61_38540	COG4565	transcriptional regulatory protein
FLK61_38545	COG3290	protein histidine kinase activity
FLK61_38555	COG3177	Filamentation induced by cAMP protein fic
FLK61_38560	COG2318	DinB family
FLK61_38585	COG1486	melibiose metabolic process
FLK61_38590	COG2188	Transcriptional regulator
FLK61_38650	COG2182	Extracellular solute-binding protein
FLK61_38665	COG1879	ABC-type sugar transport system periplasmic component
FLK61_38670	COG1172	Belongs to the binding-protein-dependent transport system permease family
FLK61_38675	COG1129	ABC transporter
FLK61_38680	COG1869	D-ribose catabolic process
FLK61_38685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_38690	COG1609	Transcriptional regulator
FLK61_38695	COG0658	competence protein
FLK61_38695	COG2333	competence protein COMEC
FLK61_38710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLK61_38715	COG1846	Transcriptional regulator
FLK61_38735	COG2207	Transcriptional regulator
FLK61_38735	COG4753	response regulator
FLK61_38750	COG3842	ATPase activity
FLK61_38785	COG2213	PTS system mannitol-specific
FLK61_38795	COG0246	Mannitol dehydrogenase
FLK61_38800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FLK61_38805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FLK61_38815	COG3328	transposase activity
FLK61_38830	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_38835	COG0277	FAD linked oxidase domain protein
FLK61_38840	COG1070	Carbohydrate kinase
FLK61_38880	COG0657	acetylesterase activity
FLK61_38895	COG2801	Transposase and inactivated derivatives
FLK61_38930	COG0655	NAD(P)H dehydrogenase (quinone) activity
FLK61_38935	COG0583	DNA-binding transcription factor activity
FLK61_38965	COG3206	protein involved in exopolysaccharide biosynthesis
FLK61_38975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLK61_39000	COG0438	transferase activity, transferring glycosyl groups
FLK61_39005	COG0438	transferase activity, transferring glycosyl groups
FLK61_39010	COG1045	serine acetyltransferase
FLK61_39015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FLK61_39020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FLK61_39025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FLK61_39035	COG4464	protein tyrosine phosphatase activity
FLK61_39040	COG0489	protein tyrosine kinase activity
FLK61_39045	COG3944	biosynthesis protein
FLK61_39060	COG3693	PFAM glycoside hydrolase, family 10
FLK61_39115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FLK61_39140	COG3328	transposase activity
FLK61_39150	COG1523	belongs to the glycosyl hydrolase 13 family
FLK61_39160	COG3266	domain, Protein
FLK61_39160	COG1361	Conserved repeat domain
FLK61_39160	COG2911	Protein conserved in bacteria
FLK61_39205	COG1472	Belongs to the glycosyl hydrolase 3 family
FLK61_39210	COG0662	Cupin 2, conserved barrel domain protein
FLK61_39210	COG2207	Transcriptional regulator
FLK61_39215	COG1361	Conserved repeat domain
FLK61_39215	COG3266	domain, Protein
FLK61_39215	COG2911	Protein conserved in bacteria
FLK61_39230	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_39240	COG3266	domain, Protein
FLK61_39240	COG2911	Protein conserved in bacteria
FLK61_39240	COG1361	Conserved repeat domain
FLK61_39245	COG1523	belongs to the glycosyl hydrolase 13 family
FLK61_39255	COG0569	domain protein
FLK61_39260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FLK61_39275	COG3275	phosphorelay sensor kinase activity
FLK61_39285	COG1966	Carbon starvation protein
FLK61_39290	COG3654	unkown
FLK61_39305	COG0745	RESPONSE REGULATOR receiver
FLK61_39310	COG5002	protein histidine kinase activity
FLK61_39345	COG0561	phosphatase activity
FLK61_39360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FLK61_39395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FLK61_39400	COG1361	Conserved repeat domain
FLK61_39410	COG5294	Protein conserved in bacteria
FLK61_39415	COG0577	efflux transmembrane transporter activity
FLK61_39420	COG1136	(ABC) transporter
FLK61_39425	COG2205	protein histidine kinase activity
FLK61_39430	COG0745	RESPONSE REGULATOR receiver
FLK61_39435	COG0778	Nitroreductase
FLK61_39470	COG0791	NLP P60 protein
FLK61_39470	COG1388	LysM domain
FLK61_39485	COG0840	transmembrane signaling receptor activity
FLK61_39495	COG1404	Belongs to the peptidase S8 family
FLK61_39500	COG0456	acetyltransferase
FLK61_39520	COG1595	DNA-templated transcription, initiation
FLK61_39535	COG2247	cell wall binding repeat
FLK61_39535	COG0860	N-Acetylmuramoyl-L-alanine amidase
FLK61_39540	COG0577	efflux transmembrane transporter activity
FLK61_39540	COG1136	(ABC) transporter
FLK61_39555	COG0789	Transcriptional regulator
FLK61_39560	COG1309	transcriptional regulator
FLK61_39565	COG2814	Major facilitator Superfamily
FLK61_39575	COG1595	DNA-templated transcription, initiation
FLK61_39600	COG0737	Belongs to the 5'-nucleotidase family
FLK61_39605	COG0840	transmembrane signaling receptor activity
FLK61_39610	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FLK61_39615	COG1737	Transcriptional regulator
FLK61_39620	COG1070	Carbohydrate kinase
FLK61_39625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLK61_39630	COG0129	dihydroxy-acid dehydratase activity
FLK61_39635	COG1414	Transcriptional regulator
FLK61_39650	COG0300	oxidoreductase activity
FLK61_39660	COG0791	NLP P60 protein
FLK61_39660	COG1388	LysM domain
FLK61_39695	COG4786	Flagellar basal body rod
FLK61_39700	COG4786	Flagellar basal body rod
FLK61_39710	COG1609	Transcriptional regulator
FLK61_39715	COG0739	heme binding
FLK61_39720	COG2385	sporulation resulting in formation of a cellular spore
FLK61_39725	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLK61_39735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FLK61_39765	COG0356	it plays a direct role in the translocation of protons across the membrane
FLK61_39780	COG1404	Belongs to the peptidase S8 family
FLK61_39790	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FLK61_39795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FLK61_39800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FLK61_39805	COG4475	Protein of unknown function (DUF436)
FLK61_39810	COG0698	ribose 5-phosphate isomerase
FLK61_39820	COG1971	Probably functions as a manganese efflux pump
FLK61_39845	COG0009	L-threonylcarbamoyladenylate synthase
FLK61_39860	COG2890	protein-(glutamine-N5) methyltransferase activity
FLK61_39865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FLK61_39875	COG2801	Transposase and inactivated derivatives
FLK61_39900	COG1435	thymidine kinase activity
FLK61_39905	COG0254	rRNA binding
FLK61_39910	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FLK61_39915	COG1494	fructose-1,6-bisphosphatase
FLK61_39920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLK61_39925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLK61_39930	COG0191	fructose-bisphosphate aldolase activity
FLK61_39935	COG2204	response regulator
FLK61_39960	COG0504	CTP synthase activity
FLK61_39965	COG3343	RNA polymerase activity
FLK61_39980	COG1703	isobutyryl-CoA mutase activity
FLK61_39985	COG1960	acyl-CoA dehydrogenase activity
FLK61_39990	COG1960	acyl-CoA dehydrogenase activity
FLK61_39995	COG1250	3-hydroxyacyl-CoA dehydrogenase
FLK61_40000	COG0183	Belongs to the thiolase family
FLK61_40015	COG0247	lactate metabolic process
FLK61_40015	COG2181	nitrate reductase activity
FLK61_40020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLK61_40030	COG0596	Alpha beta hydrolase
FLK61_40050	COG0018	arginyl-trna synthetase
FLK61_40070	COG0010	Belongs to the arginase family
FLK61_40075	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FLK61_40090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FLK61_40105	COG1942	4-Oxalocrotonate Tautomerase
FLK61_40115	COG0384	phenazine biosynthesis protein PhzF
FLK61_40125	COG3465	dGTPase activity
FLK61_40130	COG1078	dGTPase activity
FLK61_40135	COG0095	Lipoate-protein ligase
FLK61_40155	COG2239	Acts as a magnesium transporter
FLK61_40165	COG1361	Conserved repeat domain
FLK61_40175	COG1609	Transcriptional regulator
FLK61_40185	COG1069	ribulokinase activity
FLK61_40205	COG0395	ABC-type sugar transport system, permease component
FLK61_40210	COG1175	transmembrane transport
FLK61_40215	COG1653	transport
FLK61_40220	COG1361	Conserved repeat domain
FLK61_40220	COG2911	Protein conserved in bacteria
FLK61_40220	COG3266	domain, Protein
FLK61_40255	COG0280	phosphate acetyltransferase
FLK61_40260	COG0446	pyridine nucleotide-disulphide oxidoreductase
FLK61_40260	COG1902	pentaerythritol trinitrate reductase activity
FLK61_40265	COG1024	Enoyl-CoA hydratase
FLK61_40275	COG1737	Transcriptional regulator
FLK61_40290	COG0395	ABC-type sugar transport system, permease component
FLK61_40295	COG1175	transmembrane transport
FLK61_40320	COG1940	carbohydrate kinase activity
FLK61_40335	COG3773	Cell wall hydrolase
FLK61_40345	COG2363	Small membrane protein
FLK61_40350	COG0456	acetyltransferase
FLK61_40375	COG0702	epimerase
FLK61_40380	COG3852	Histidine kinase
FLK61_40385	COG2084	Dehydrogenase
FLK61_40390	COG0656	L-ascorbic acid biosynthetic process
FLK61_40395	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FLK61_40400	COG2201	protein-glutamate methylesterase activity
FLK61_40405	COG1621	beta-fructofuranosidase activity
FLK61_40410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLK61_40415	COG0840	transmembrane signaling receptor activity
FLK61_40430	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FLK61_40450	COG1368	sulfuric ester hydrolase activity
FLK61_40455	COG2309	aminopeptidase activity
FLK61_40460	COG0024	Methionine aminopeptidase
FLK61_40465	COG1115	amino acid carrier protein
FLK61_40480	COG1072	(Pantothenic acid kinase))
FLK61_40495	COG2308	Evidence 4 Homologs of previously reported genes of
FLK61_40500	COG0723	plastoquinol--plastocyanin reductase activity
FLK61_40500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FLK61_40505	COG1473	amidohydrolase
FLK61_40535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FLK61_40575	COG3046	protein related to deoxyribodipyrimidine photolyase
FLK61_40580	COG5002	protein histidine kinase activity
FLK61_40585	COG0745	RESPONSE REGULATOR receiver
FLK61_40605	COG0460	homoserine dehydrogenase
FLK61_40610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FLK61_40615	COG0083	homoserine kinase activity
FLK61_40620	COG0778	Nitroreductase
FLK61_40630	COG0561	phosphatase activity
FLK61_40635	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FLK61_40650	COG0527	aspartate kinase activity
FLK61_40655	COG0747	negative chemotaxis
FLK61_40665	COG0601	transmembrane transport
FLK61_40670	COG0444	Belongs to the ABC transporter superfamily
FLK61_40675	COG4608	Belongs to the ABC transporter superfamily
FLK61_40695	COG3842	ATPase activity
FLK61_40700	COG3833	ABC-type maltose transport systems, permease component
FLK61_40710	COG4134	Bacterial extracellular solute-binding protein
FLK61_40720	COG1607	acyl-coa hydrolase
FLK61_40735	COG0493	'glutamate synthase
FLK61_40740	COG0069	glutamate synthase activity
FLK61_40740	COG0070	glutamate synthase
FLK61_40740	COG0067	glutamate synthase
FLK61_40750	COG1090	epimerase
FLK61_40755	COG1119	ATPase activity
FLK61_40765	COG1126	abc transporter atp-binding protein
FLK61_40770	COG0765	amino acid transport
FLK61_40775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FLK61_40785	COG1115	amino acid carrier protein
FLK61_40790	COG0655	NAD(P)H dehydrogenase (quinone) activity
FLK61_40795	COG1404	Belongs to the peptidase S8 family
FLK61_40815	COG2223	nitrite transmembrane transporter activity
FLK61_40825	COG0726	polysaccharide deacetylase
FLK61_40840	COG2267	carboxylic ester hydrolase activity
FLK61_40855	COG5001	Diguanylate cyclase
FLK61_40855	COG3300	MHYT domain
FLK61_40860	COG0446	pyridine nucleotide-disulphide oxidoreductase
FLK61_40875	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_40880	COG1070	Carbohydrate kinase
FLK61_40885	COG2115	Belongs to the xylose isomerase family
FLK61_40895	COG1028	Short-chain dehydrogenase reductase Sdr
FLK61_40905	COG1802	Transcriptional regulator
FLK61_40915	COG0395	ABC-type sugar transport system, permease component
FLK61_40920	COG4209	transmembrane transport
FLK61_40925	COG1653	transport
FLK61_40930	COG5578	integral membrane protein
FLK61_40940	COG2972	Histidine kinase
FLK61_40950	COG1653	transport
FLK61_40960	COG0395	ABC-type sugar transport system, permease component
FLK61_40965	COG3507	Belongs to the glycosyl hydrolase 43 family
FLK61_40970	COG5578	integral membrane protein
FLK61_40975	COG3693	PFAM glycoside hydrolase, family 10
FLK61_41000	COG2182	Extracellular solute-binding protein
FLK61_41005	COG1175	transmembrane transport
FLK61_41010	COG3833	ABC-type maltose transport systems, permease component
FLK61_41015	COG1874	Beta-galactosidase
FLK61_41025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_41055	COG0745	RESPONSE REGULATOR receiver
FLK61_41070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLK61_41090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_41095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLK61_41100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FLK61_41115	COG1307	EDD domain protein, DegV family
FLK61_41130	COG0789	Transcriptional regulator
FLK61_41135	COG0840	transmembrane signaling receptor activity
FLK61_41140	COG1609	Transcriptional regulator
FLK61_41155	COG0454	-acetyltransferase
FLK61_41195	COG2205	protein histidine kinase activity
FLK61_41200	COG0745	RESPONSE REGULATOR receiver
FLK61_41205	COG1136	(ABC) transporter
FLK61_41210	COG0577	efflux transmembrane transporter activity
FLK61_41225	COG0730	response to heat
FLK61_41230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK61_41230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FLK61_41235	COG2210	Belongs to the sulfur carrier protein TusA family
FLK61_41240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLK61_41240	COG0425	Belongs to the sulfur carrier protein TusA family
FLK61_41275	COG0688	phosphatidylethanolamine metabolic process
FLK61_41285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLK61_41305	COG0456	acetyltransferase
FLK61_41315	COG2814	Major facilitator Superfamily
FLK61_41320	COG1309	transcriptional regulator
FLK61_41325	COG0745	RESPONSE REGULATOR receiver
FLK61_41335	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FLK61_41340	COG1061	Type III restriction enzyme res subunit
FLK61_41365	COG2226	methyltransferase
FLK61_41370	COG3708	Transcriptional regulator
FLK61_41370	COG2207	Transcriptional regulator
FLK61_41380	COG1834	amidinotransferase
FLK61_41385	COG3403	YqcI/YcgG family
FLK61_41395	COG1595	DNA-templated transcription, initiation
FLK61_41470	COG1401	restriction endodeoxyribonuclease activity
FLK61_41490	COG2801	Transposase and inactivated derivatives
FLK61_41515	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FLK61_41555	COG0415	Belongs to the DNA photolyase family
FLK61_41565	COG3706	GGDEF domain
FLK61_41580	COG0747	negative chemotaxis
FLK61_41585	COG4608	Belongs to the ABC transporter superfamily
FLK61_41590	COG0444	Belongs to the ABC transporter superfamily
FLK61_41595	COG1012	belongs to the aldehyde dehydrogenase family
FLK61_41615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLK61_41620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FLK61_41625	COG4853	Protein conserved in bacteria
FLK61_41630	COG4863	YycH protein
FLK61_41635	COG5002	protein histidine kinase activity
FLK61_41640	COG0745	RESPONSE REGULATOR receiver
FLK61_41655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FLK61_41660	COG0305	Participates in initiation and elongation during chromosome replication
FLK61_41665	COG0359	binds to the 23S rRNA
FLK61_41670	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FLK61_41675	COG4241	membrane
FLK61_41685	COG1174	glycine betaine transport
FLK61_41690	COG0517	IMP dehydrogenase activity
FLK61_41690	COG1125	glycine betaine transport
FLK61_41700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FLK61_41705	COG0629	single-stranded DNA binding
FLK61_41710	COG0360	Binds together with S18 to 16S ribosomal RNA
FLK61_41715	COG0012	GTP binding
FLK61_41720	COG4481	Protein conserved in bacteria
FLK61_41725	COG3949	Membrane
FLK61_41735	COG1811	Na channel or pump
FLK61_41740	COG1475	DNA binding
FLK61_41745	COG1192	Involved in chromosome partitioning
FLK61_41750	COG1475	DNA binding
FLK61_41755	COG0357	Ribosomal RNA small subunit methyltransferase G
FLK61_41760	COG0445	tRNA wobble uridine modification
FLK61_41765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FLK61_41770	COG1847	R3H domain protein
FLK61_41775	COG0706	membrane insertase activity
FLK61_41780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FLK61_41790	COG0230	Belongs to the bacterial ribosomal protein bL34 family