locus-tag	class	description
CDO84_00035	COG0738	Major facilitator superfamily
CDO84_00040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO84_00050	COG1063	alcohol dehydrogenase
CDO84_00055	COG0659	secondary active sulfate transmembrane transporter activity
CDO84_00060	COG0385	Bile acid
CDO84_00065	COG2819	hydrolase of the alpha beta superfamily
CDO84_00070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_00075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_00080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDO84_00085	COG2207	Transcriptional regulator
CDO84_00085	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDO84_00090	COG3876	Protein conserved in bacteria
CDO84_00095	COG1472	Belongs to the glycosyl hydrolase 3 family
CDO84_00100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDO84_00105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_00105	COG1263	PTS System
CDO84_00110	COG1737	Transcriptional regulator
CDO84_00115	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDO84_00120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_00125	COG1683	Conserved Protein
CDO84_00155	COG1595	DNA-templated transcription, initiation
CDO84_00160	COG5662	AntiSigma factor
CDO84_00165	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDO84_00170	COG4856	YbbR-like protein
CDO84_00175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO84_00180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDO84_00185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CDO84_00190	COG2169	Transcriptional regulator
CDO84_00195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO84_00200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO84_00205	COG3002	Belongs to the UPF0753 family
CDO84_00210	COG0288	reversible hydration of carbon dioxide
CDO84_00220	COG5609	conserved protein (DUF2294)
CDO84_00225	COG0640	Transcriptional regulator
CDO84_00230	COG2814	Major facilitator Superfamily
CDO84_00245	COG0596	Alpha beta hydrolase
CDO84_00250	COG0745	RESPONSE REGULATOR receiver
CDO84_00255	COG0642	Histidine kinase
CDO84_00265	COG0515	serine threonine protein kinase
CDO84_00280	COG1113	amino acid transport
CDO84_00295	COG2602	Beta-lactamase
CDO84_00300	COG2124	cytochrome p450
CDO84_00310	COG0531	amino acid
CDO84_00315	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDO84_00320	COG0584	glycerophosphoryl diester phosphodiesterase
CDO84_00325	COG2271	Major facilitator Superfamily
CDO84_00340	COG1846	Transcriptional regulator
CDO84_00340	COG0456	acetyltransferase
CDO84_00345	COG2271	Major facilitator Superfamily
CDO84_00355	COG0697	spore germination
CDO84_00360	COG1917	Cupin 2, conserved barrel domain protein
CDO84_00360	COG2207	Transcriptional regulator
CDO84_00365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CDO84_00370	COG3591	Belongs to the peptidase S1B family
CDO84_00380	COG0596	Alpha beta hydrolase
CDO84_00385	COG1183	phosphatidylcholine synthase activity
CDO84_00390	COG0586	Pfam SNARE associated Golgi protein
CDO84_00395	COG0688	phosphatidylethanolamine metabolic process
CDO84_00405	COG2312	Erythromycin esterase
CDO84_00410	COG2207	Transcriptional regulator
CDO84_00420	COG1301	dicarboxylic acid transport
CDO84_00425	COG2190	(PTS) system
CDO84_00425	COG1263	PTS System
CDO84_00425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_00430	COG0363	glucosamine-6-phosphate deaminase activity
CDO84_00445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO84_00450	COG0833	amino acid
CDO84_00455	COG2040	homocysteine
CDO84_00460	COG1115	amino acid carrier protein
CDO84_00465	COG2066	Belongs to the glutaminase family
CDO84_00470	COG4191	Histidine kinase
CDO84_00475	COG0784	Response regulator, receiver
CDO84_00480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO84_00485	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_00490	COG2271	Major facilitator Superfamily
CDO84_00495	COG4948	Mandelate Racemase Muconate Lactonizing
CDO84_00500	COG2186	Transcriptional regulator
CDO84_00505	COG2721	sulfolactate sulfo-lyase activity
CDO84_00510	COG3173	Aminoglycoside phosphotransferase
CDO84_00520	COG0697	spore germination
CDO84_00525	COG0745	RESPONSE REGULATOR receiver
CDO84_00530	COG2205	protein histidine kinase activity
CDO84_00535	COG1131	(ABC) transporter
CDO84_00550	COG3773	Cell wall hydrolase
CDO84_00565	COG3540	Alkaline phosphatase
CDO84_00570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO84_00575	COG0805	protein transport
CDO84_00580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CDO84_00585	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDO84_00590	COG0477	Major facilitator Superfamily
CDO84_00595	COG1309	transcriptional regulator
CDO84_00600	COG0252	asparaginase activity
CDO84_00605	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CDO84_00610	COG1714	RDD family
CDO84_00615	COG1405	negative regulation of cell septum assembly
CDO84_00615	COG3012	SEC-C Motif Domain Protein
CDO84_00620	COG3290	protein histidine kinase activity
CDO84_00625	COG3279	Response regulator of the LytR AlgR family
CDO84_00630	COG4555	ABC transporter
CDO84_00635	COG1668	transmembrane transport
CDO84_00640	COG0667	Aldo Keto reductase
CDO84_00650	COG1595	DNA-templated transcription, initiation
CDO84_00660	COG1595	DNA-templated transcription, initiation
CDO84_00665	COG1876	peptidase activity
CDO84_00670	COG0457	Tetratricopeptide repeat
CDO84_00675	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_00680	COG0366	Alpha amylase catalytic
CDO84_00685	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDO84_00690	COG1121	(ABC) transporter
CDO84_00695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO84_00700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO84_00705	COG2310	stress, protein
CDO84_00710	COG2310	stress, protein
CDO84_00715	COG2310	stress, protein
CDO84_00720	COG0861	Integral membrane protein TerC family
CDO84_00730	COG3853	Toxic anion resistance protein (TelA)
CDO84_00735	COG0477	Major facilitator Superfamily
CDO84_00740	COG2814	Major facilitator Superfamily
CDO84_00745	COG0640	Transcriptional regulator
CDO84_00750	COG4175	Glycine betaine
CDO84_00750	COG0517	IMP dehydrogenase activity
CDO84_00755	COG4176	ABC-type proline glycine betaine transport system permease component
CDO84_00760	COG2113	Glycine betaine
CDO84_00765	COG1473	amidohydrolase
CDO84_00770	COG1288	antiporter activity
CDO84_00780	COG0366	Alpha amylase catalytic
CDO84_00785	COG0039	L-malate dehydrogenase activity
CDO84_00790	COG1620	l-lactate permease
CDO84_00795	COG2814	Major facilitator Superfamily
CDO84_00800	COG1846	Transcriptional regulator
CDO84_00805	COG1280	lysine exporter protein (LysE YggA)
CDO84_00810	COG3403	YqcI/YcgG family
CDO84_00815	COG1113	amino acid transport
CDO84_00820	COG3665	Urea carboxylase-associated protein
CDO84_00825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDO84_00830	COG1660	Displays ATPase and GTPase activities
CDO84_00835	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDO84_00840	COG2226	methyltransferase
CDO84_00845	COG0583	DNA-binding transcription factor activity
CDO84_00850	COG3458	cephalosporin-C deacetylase activity
CDO84_00855	COG3541	Predicted nucleotidyltransferase
CDO84_00860	COG0506	proline dehydrogenase activity
CDO84_00865	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_00870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDO84_00875	COG2508	Transcriptional regulator
CDO84_00880	COG3689	TIGRFAM TIGR03943 family protein
CDO84_00885	COG0701	Predicted permease
CDO84_00890	COG2267	carboxylic ester hydrolase activity
CDO84_00895	COG0492	ferredoxin-NADP+ reductase activity
CDO84_00900	COG1587	Uroporphyrinogen-III synthase
CDO84_00900	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO84_00905	COG2146	nitrite reductase [NAD(P)H] activity
CDO84_00910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO84_00915	COG0243	molybdopterin cofactor binding
CDO84_00920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO84_00925	COG2223	nitrite transmembrane transporter activity
CDO84_00930	COG1469	GTP cyclohydrolase I activity
CDO84_00935	COG1376	ErfK ybiS ycfS ynhG family protein
CDO84_00940	COG0523	cobalamin synthesis protein
CDO84_00945	COG0765	amino acid transport
CDO84_00950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO84_00955	COG1714	RDD family
CDO84_00965	COG2723	6-phospho-beta-galactosidase activity
CDO84_00975	COG3209	COG3209 Rhs family protein
CDO84_00980	COG0840	transmembrane signaling receptor activity
CDO84_00980	COG3290	protein histidine kinase activity
CDO84_00985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDO84_00990	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CDO84_00995	COG1733	regulation of RNA biosynthetic process
CDO84_01000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_01005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_01010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_01015	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CDO84_01020	COG2814	Major facilitator Superfamily
CDO84_01030	COG0697	spore germination
CDO84_01035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_01045	COG2364	Membrane
CDO84_01050	COG1126	abc transporter atp-binding protein
CDO84_01055	COG0765	amino acid transport
CDO84_01060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO84_01065	COG0583	DNA-binding transcription factor activity
CDO84_01070	COG0163	prenyltransferase activity
CDO84_01075	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDO84_01090	COG0596	Alpha beta hydrolase
CDO84_01095	COG3104	oligopeptide transport
CDO84_01100	COG5434	Belongs to the glycosyl hydrolase 28 family
CDO84_01110	COG0697	spore germination
CDO84_01120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CDO84_01125	COG1136	(ABC) transporter
CDO84_01130	COG0577	efflux transmembrane transporter activity
CDO84_01135	COG0745	RESPONSE REGULATOR receiver
CDO84_01140	COG3850	Histidine kinase
CDO84_01140	COG5002	protein histidine kinase activity
CDO84_01145	COG0457	Tetratricopeptide repeat
CDO84_01160	COG0527	aspartate kinase activity
CDO84_01165	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_01170	COG4605	iron ion homeostasis
CDO84_01175	COG4604	ABC transporter, ATP-binding protein
CDO84_01180	COG4607	ABC-type enterochelin transport system periplasmic component
CDO84_01185	COG2814	Major facilitator Superfamily
CDO84_01190	COG1309	transcriptional regulator
CDO84_01195	COG0778	Nitroreductase
CDO84_01200	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CDO84_01205	COG0640	Transcriptional regulator
CDO84_01210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_01215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CDO84_01220	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_01225	COG4975	Glucose uptake
CDO84_01230	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_01235	COG4549	nuclear export factor GLE1
CDO84_01240	COG2372	response to copper ion
CDO84_01240	COG1276	copper resistance
CDO84_01245	COG1349	DNA-binding transcription factor activity
CDO84_01255	COG2213	PTS system mannitol-specific
CDO84_01260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_01265	COG0246	Mannitol dehydrogenase
CDO84_01270	COG0473	3-isopropylmalate dehydrogenase activity
CDO84_01275	COG0681	Belongs to the peptidase S26 family
CDO84_01280	COG0412	Dienelactone hydrolase
CDO84_01285	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO84_01295	COG0561	phosphatase activity
CDO84_01300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CDO84_01305	COG1914	H( )-stimulated, divalent metal cation uptake system
CDO84_01310	COG4336	lyase activity
CDO84_01315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CDO84_01320	COG1984	allophanate hydrolase subunit 2
CDO84_01325	COG1414	Transcriptional regulator
CDO84_01330	COG2755	lipolytic protein G-D-S-L family
CDO84_01340	COG2329	Antibiotic biosynthesis monooxygenase
CDO84_01345	COG0768	penicillin binding
CDO84_01350	COG4989	oxidoreductase activity
CDO84_01355	COG3711	transcriptional antiterminator
CDO84_01360	COG0318	PFAM AMP-dependent synthetase and ligase
CDO84_01365	COG2226	methyltransferase
CDO84_01370	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_01375	COG1917	Cupin 2, conserved barrel domain protein
CDO84_01380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_01385	COG3871	stress protein (general stress protein 26)
CDO84_01395	COG2814	Major facilitator Superfamily
CDO84_01400	COG1522	sequence-specific DNA binding
CDO84_01405	COG0551	DNA topoisomerase type I activity
CDO84_01405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDO84_01410	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CDO84_01415	COG3706	GGDEF domain
CDO84_01420	COG5298	Protein conserved in bacteria
CDO84_01425	COG1215	transferase activity, transferring glycosyl groups
CDO84_01435	COG0531	amino acid
CDO84_01440	COG0494	nUDIX hydrolase
CDO84_01445	COG0028	Belongs to the TPP enzyme family
CDO84_01460	COG1914	H( )-stimulated, divalent metal cation uptake system
CDO84_01465	COG2261	transglycosylase associated protein
CDO84_01470	COG4876	unkown
CDO84_01475	COG2217	Heavy metal translocating P-type atpase
CDO84_01480	COG3729	General stress protein
CDO84_01485	COG0662	Cupin 2, conserved barrel domain protein
CDO84_01490	COG2329	Antibiotic biosynthesis monooxygenase
CDO84_01495	COG3546	catalase activity
CDO84_01500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CDO84_01505	COG3290	protein histidine kinase activity
CDO84_01510	COG4565	transcriptional regulatory protein
CDO84_01515	COG1301	dicarboxylic acid transport
CDO84_01520	COG0628	permease
CDO84_01525	COG1301	dicarboxylic acid transport
CDO84_01530	COG1131	(ABC) transporter
CDO84_01535	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CDO84_01545	COG1960	acyl-CoA dehydrogenase activity
CDO84_01560	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO84_01565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_01570	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDO84_01575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDO84_01585	COG0513	Belongs to the DEAD box helicase family
CDO84_01590	COG3402	PFAM membrane-flanked domain
CDO84_01595	COG3428	Bacterial PH domain
CDO84_01600	COG0705	Rhomboid family
CDO84_01605	COG0736	holo-[acyl-carrier-protein] synthase activity
CDO84_01610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CDO84_01615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDO84_01620	COG0864	Transcriptional regulator
CDO84_01625	COG2337	Toxic component of a toxin-antitoxin (TA) module
CDO84_01630	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_01635	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_01640	COG2172	sigma factor antagonist activity
CDO84_01645	COG2208	phosphoserine phosphatase activity
CDO84_01650	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_01655	COG2172	sigma factor antagonist activity
CDO84_01660	COG1191	sigma factor activity
CDO84_01665	COG2208	phosphoserine phosphatase activity
CDO84_01675	COG1673	EVE domain
CDO84_01680	COG1846	Transcriptional regulator
CDO84_01685	COG2183	response to ionizing radiation
CDO84_01695	COG3091	SprT-like family
CDO84_01735	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_01775	COG1396	sequence-specific DNA binding
CDO84_01800	COG0737	Belongs to the 5'-nucleotidase family
CDO84_01805	COG3764	Sortase (surface protein transpeptidase)
CDO84_01810	COG1278	Cold shock
CDO84_01815	COG0697	spore germination
CDO84_01820	COG1917	Cupin 2, conserved barrel domain protein
CDO84_01820	COG2207	Transcriptional regulator
CDO84_01825	COG0697	spore germination
CDO84_01830	COG2207	Transcriptional regulator
CDO84_01830	COG3708	Transcriptional regulator
CDO84_01835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_01840	COG0477	Major facilitator Superfamily
CDO84_01850	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
CDO84_01860	COG0697	spore germination
CDO84_01865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_01870	COG2030	dehydratase
CDO84_01875	COG3545	Serine hydrolase
CDO84_01880	COG1733	regulation of RNA biosynthetic process
CDO84_01885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDO84_01890	COG2814	Major facilitator Superfamily
CDO84_01895	COG1309	transcriptional regulator
CDO84_01905	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CDO84_01915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_01925	COG0726	polysaccharide deacetylase
CDO84_01935	COG5002	protein histidine kinase activity
CDO84_01940	COG0745	RESPONSE REGULATOR receiver
CDO84_01945	COG0697	spore germination
CDO84_01950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_01955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDO84_01960	COG0640	Transcriptional regulator
CDO84_01965	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO84_01980	COG4585	Histidine kinase
CDO84_01985	COG2197	response regulator
CDO84_01990	COG2409	Drug exporters of the RND superfamily
CDO84_01995	COG0596	Alpha beta hydrolase
CDO84_02005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_02010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CDO84_02015	COG1687	branched-chain amino acid
CDO84_02020	COG1114	Component of the transport system for branched-chain amino acids
CDO84_02030	COG1811	Na channel or pump
CDO84_02035	COG0789	Transcriptional regulator
CDO84_02035	COG4978	Transcriptional regulator
CDO84_02040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO84_02045	COG0778	Nitroreductase
CDO84_02050	COG0346	lactoylglutathione lyase activity
CDO84_02055	COG2259	Doxx family
CDO84_02060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_02075	COG2323	membrane
CDO84_02080	COG2323	membrane
CDO84_02085	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO84_02100	COG1309	transcriptional regulator
CDO84_02110	COG0456	acetyltransferase
CDO84_02120	COG1113	amino acid transport
CDO84_02125	COG2318	DinB family
CDO84_02130	COG1846	Transcriptional regulator
CDO84_02135	COG2409	Drug exporters of the RND superfamily
CDO84_02135	COG1033	growth of symbiont in host cell
CDO84_02140	COG0778	Nitroreductase
CDO84_02145	COG1846	Transcriptional regulator
CDO84_02150	COG2814	Major facilitator Superfamily
CDO84_02155	COG0730	response to heat
CDO84_02160	COG1802	Transcriptional regulator
CDO84_02165	COG1388	LysM domain
CDO84_02165	COG3858	chitin binding
CDO84_02170	COG1819	glycosyl
CDO84_02180	COG1785	Belongs to the alkaline phosphatase family
CDO84_02185	COG5646	InterPro IPR014922
CDO84_02195	COG0454	-acetyltransferase
CDO84_02200	COG1078	dGTPase activity
CDO84_02205	COG1388	LysM domain
CDO84_02210	COG2814	Major facilitator Superfamily
CDO84_02215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDO84_02220	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDO84_02225	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDO84_02230	COG2723	6-phospho-beta-galactosidase activity
CDO84_02235	COG2188	Transcriptional regulator
CDO84_02240	COG1940	carbohydrate kinase activity
CDO84_02245	COG1482	cell wall glycoprotein biosynthetic process
CDO84_02250	COG4124	Belongs to the glycosyl hydrolase 26 family
CDO84_02295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDO84_02300	COG0802	atpase or kinase
CDO84_02305	COG1214	PFAM Peptidase M22, glycoprotease
CDO84_02310	COG0456	acetyltransferase
CDO84_02315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDO84_02320	COG0488	(ABC) transporter
CDO84_02325	COG0315	cyclic pyranopterin monophosphate synthase activity
CDO84_02330	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CDO84_02335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO84_02340	COG0805	protein transport
CDO84_02350	COG1266	CAAX protease self-immunity
CDO84_02355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDO84_02360	COG0459	protein refolding
CDO84_02365	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_02380	COG0457	Tetratricopeptide repeat
CDO84_02385	COG1063	alcohol dehydrogenase
CDO84_02390	COG2211	Major facilitator Superfamily
CDO84_02395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO84_02400	COG1842	Phage shock protein A
CDO84_02405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDO84_02410	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CDO84_02415	COG4260	virion core protein, lumpy skin disease virus
CDO84_02425	COG2814	Major facilitator Superfamily
CDO84_02430	COG1063	alcohol dehydrogenase
CDO84_02435	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDO84_02440	COG0823	Involved in the tonB-independent uptake of proteins
CDO84_02455	COG2267	carboxylic ester hydrolase activity
CDO84_02465	COG2132	Multicopper oxidase
CDO84_02470	COG1113	amino acid transport
CDO84_02480	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDO84_02485	COG0714	Associated with various cellular activities
CDO84_02490	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CDO84_02495	COG1305	Transglutaminase-like
CDO84_02500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDO84_02500	COG0519	Catalyzes the synthesis of GMP from XMP
CDO84_02515	COG2252	PERMEase
CDO84_02520	COG3064	Membrane
CDO84_02530	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
CDO84_02540	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDO84_02545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDO84_02550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDO84_02555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDO84_02560	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO84_02565	COG0047	phosphoribosylformylglycinamidine synthase activity
CDO84_02570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDO84_02575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDO84_02580	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDO84_02585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDO84_02590	COG0138	bifunctional purine biosynthesis protein purh
CDO84_02595	COG0151	Belongs to the GarS family
CDO84_02600	COG1522	sequence-specific DNA binding
CDO84_02605	COG0531	amino acid
CDO84_02615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO84_02620	COG1470	cell adhesion involved in biofilm formation
CDO84_02625	COG4496	protein, YerC YecD
CDO84_02630	COG0069	glutamate synthase activity
CDO84_02635	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CDO84_02640	COG0210	DNA helicase
CDO84_02645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDO84_02650	COG4851	CamS sex pheromone cAM373 precursor
CDO84_02655	COG2211	Major facilitator Superfamily
CDO84_02665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDO84_02680	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO84_02695	COG1960	acyl-CoA dehydrogenase activity
CDO84_02725	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO84_02730	COG1785	Belongs to the alkaline phosphatase family
CDO84_02740	COG1285	pathogenesis
CDO84_02745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDO84_02750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO84_02755	COG0154	amidase activity
CDO84_02760	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDO84_02770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDO84_02775	COG1597	lipid kinase activity
CDO84_02780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDO84_02805	COG0457	Tetratricopeptide repeat
CDO84_02825	COG5444	nuclease activity
CDO84_02835	COG3586	endonuclease activity
CDO84_02845	COG2323	membrane
CDO84_02850	COG0457	Tetratricopeptide repeat
CDO84_02860	COG0217	transcriptional regulatory protein
CDO84_02870	COG1309	transcriptional regulator
CDO84_02875	COG3631	Ketosteroid isomerase-related protein
CDO84_02895	COG3546	catalase activity
CDO84_02900	COG0454	-acetyltransferase
CDO84_02910	COG5578	integral membrane protein
CDO84_02915	COG2972	Histidine kinase
CDO84_02920	COG2207	Transcriptional regulator
CDO84_02920	COG4753	response regulator
CDO84_02925	COG1653	transport
CDO84_02930	COG1175	transmembrane transport
CDO84_02935	COG0395	ABC-type sugar transport system, permease component
CDO84_02940	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CDO84_02945	COG2207	Transcriptional regulator
CDO84_02950	COG2755	lipolytic protein G-D-S-L family
CDO84_02960	COG5578	integral membrane protein
CDO84_02965	COG3401	FG-GAP repeat protein
CDO84_02970	COG3401	FG-GAP repeat protein
CDO84_02975	COG2755	lipolytic protein G-D-S-L family
CDO84_02980	COG1874	Beta-galactosidase
CDO84_02990	COG1653	transport
CDO84_02995	COG4209	transmembrane transport
CDO84_03000	COG0395	ABC-type sugar transport system, permease component
CDO84_03005	COG1486	melibiose metabolic process
CDO84_03010	COG2323	membrane
CDO84_03015	COG2329	Antibiotic biosynthesis monooxygenase
CDO84_03020	COG0346	lactoylglutathione lyase activity
CDO84_03035	COG5583	Uncharacterized small protein (DUF2292)
CDO84_03040	COG0670	Belongs to the BI1 family
CDO84_03045	COG0697	spore germination
CDO84_03055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO84_03065	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDO84_03065	COG2124	cytochrome p450
CDO84_03070	COG1368	sulfuric ester hydrolase activity
CDO84_03075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDO84_03080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO84_03085	COG1442	glycosyl transferase family 8
CDO84_03090	COG1216	Glycosyl transferase, family 2
CDO84_03095	COG1442	glycosyl transferase family 8
CDO84_03100	COG2223	nitrite transmembrane transporter activity
CDO84_03105	COG1011	Hydrolase
CDO84_03110	COG0531	amino acid
CDO84_03115	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_03120	COG0840	transmembrane signaling receptor activity
CDO84_03125	COG0488	(ABC) transporter
CDO84_03135	COG0789	Transcriptional regulator
CDO84_03140	COG2814	Major facilitator Superfamily
CDO84_03145	COG0488	(ABC) transporter
CDO84_03150	COG0513	Belongs to the DEAD box helicase family
CDO84_03155	COG0456	acetyltransferase
CDO84_03160	COG2130	NADP-dependent
CDO84_03165	COG1120	ATPase activity
CDO84_03170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_03175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_03180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CDO84_03200	COG3866	Pectate lyase
CDO84_03205	COG0471	metal ion transport
CDO84_03225	COG0463	Glycosyl transferase, family 2
CDO84_03225	COG0457	Tetratricopeptide repeat
CDO84_03230	COG1215	transferase activity, transferring glycosyl groups
CDO84_03235	COG3290	protein histidine kinase activity
CDO84_03240	COG4565	transcriptional regulatory protein
CDO84_03245	COG3181	Tripartite tricarboxylate transporter family receptor
CDO84_03250	COG2851	Citrate transporter
CDO84_03255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_03260	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CDO84_03265	COG1254	Belongs to the acylphosphatase family
CDO84_03270	COG2258	MOSC domain
CDO84_03290	COG0024	Methionine aminopeptidase
CDO84_03295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_03295	COG1263	PTS System
CDO84_03300	COG1368	sulfuric ester hydrolase activity
CDO84_03315	COG1115	amino acid carrier protein
CDO84_03330	COG1263	PTS System
CDO84_03330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_03335	COG0366	Alpha amylase catalytic
CDO84_03340	COG2188	Transcriptional regulator
CDO84_03345	COG0778	Nitroreductase
CDO84_03350	COG0737	Belongs to the 5'-nucleotidase family
CDO84_03355	COG0693	protein deglycase activity
CDO84_03360	COG2814	Major facilitator Superfamily
CDO84_03365	COG4840	Belongs to the UPF0435 family
CDO84_03370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDO84_03375	COG4980	gas vesicle protein
CDO84_03380	COG1295	ribonuclease BN
CDO84_03385	COG0477	Major facilitator Superfamily
CDO84_03390	COG0387	Pfam Sodium calcium exchanger
CDO84_03400	COG0668	transmembrane transport
CDO84_03405	COG0535	radical SAM domain protein
CDO84_03415	COG0726	polysaccharide deacetylase
CDO84_03420	COG2084	Dehydrogenase
CDO84_03425	COG0598	Magnesium transport protein CorA
CDO84_03430	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CDO84_03435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDO84_03445	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO84_03455	COG4637	Psort location Cytoplasmic, score
CDO84_03465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO84_03470	COG0022	dehydrogenase e1 component
CDO84_03475	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO84_03480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO84_03485	COG3284	Transcriptional regulator
CDO84_03495	COG1742	UPF0060 membrane protein
CDO84_03515	COG4842	Belongs to the WXG100 family
CDO84_03520	COG1486	melibiose metabolic process
CDO84_03525	COG1737	Transcriptional regulator
CDO84_03530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_03530	COG1263	PTS System
CDO84_03535	COG1132	(ABC) transporter
CDO84_03540	COG1132	(ABC) transporter
CDO84_03545	COG2259	Doxx family
CDO84_03550	COG2514	catechol 2,3-dioxygenase activity
CDO84_03555	COG4585	Histidine kinase
CDO84_03560	COG2197	response regulator
CDO84_03570	COG1131	(ABC) transporter
CDO84_03575	COG1511	domain protein
CDO84_03575	COG0842	Transport permease protein
CDO84_03580	COG0842	Transport permease protein
CDO84_03590	COG1695	Transcriptional regulator
CDO84_03595	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CDO84_03600	COG1309	transcriptional regulator
CDO84_03605	COG2814	Major facilitator Superfamily
CDO84_03610	COG2318	DinB family
CDO84_03615	COG2814	Major facilitator Superfamily
CDO84_03620	COG1846	Transcriptional regulator
CDO84_03625	COG0392	lysyltransferase activity
CDO84_03625	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CDO84_03630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDO84_03640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_03645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_03650	COG0384	phenazine biosynthesis protein PhzF
CDO84_03655	COG0778	Nitroreductase
CDO84_03670	COG1090	epimerase
CDO84_03675	COG2137	regulation of response to DNA damage stimulus
CDO84_03685	COG2814	Major facilitator Superfamily
CDO84_03700	COG3103	Sh3 type 3 domain protein
CDO84_03705	COG5658	integral membrane protein
CDO84_03710	COG0596	Alpha beta hydrolase
CDO84_03715	COG0463	Glycosyl transferase, family 2
CDO84_03720	COG4485	Bacterial membrane protein, YfhO
CDO84_03725	COG1988	membrane-bound metal-dependent
CDO84_03730	COG1194	a g-specific adenine glycosylase
CDO84_03740	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_03755	COG3557	Belongs to the UPF0374 family
CDO84_03760	COG1132	(ABC) transporter
CDO84_03765	COG4129	membrane
CDO84_03770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDO84_03775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDO84_03780	COG0735	belongs to the Fur family
CDO84_03890	COG4326	sporulation control protein
CDO84_03900	COG5577	PFAM Coat F domain
CDO84_03905	COG3340	Belongs to the peptidase S51 family
CDO84_03910	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDO84_03915	COG0277	FAD linked oxidase domain protein
CDO84_03925	COG0753	catalase activity
CDO84_03930	COG1116	anion transmembrane transporter activity
CDO84_03935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO84_03940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO84_03945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO84_03955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDO84_03965	COG1476	TRANSCRIPTIONal
CDO84_03975	COG3382	B3 4 domain protein
CDO84_03980	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDO84_03990	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDO84_03995	COG0789	Transcriptional regulator
CDO84_04000	COG1664	Polymer-forming cytoskeletal
CDO84_04005	COG1664	Polymer-forming cytoskeletal
CDO84_04010	COG2766	serine protein kinase
CDO84_04015	COG2718	Belongs to the UPF0229 family
CDO84_04020	COG1846	Transcriptional regulator
CDO84_04025	COG1566	PFAM secretion protein HlyD family protein
CDO84_04030	COG2814	Major facilitator Superfamily
CDO84_04035	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDO84_04055	COG1725	Transcriptional regulator
CDO84_04060	COG1131	(ABC) transporter
CDO84_04065	COG1131	(ABC) transporter
CDO84_04070	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CDO84_04075	COG1278	Cold shock
CDO84_04085	COG1464	Belongs to the NlpA lipoprotein family
CDO84_04090	COG3706	GGDEF domain
CDO84_04095	COG1823	symporter activity
CDO84_04125	COG5577	PFAM Coat F domain
CDO84_04130	COG0737	Belongs to the 5'-nucleotidase family
CDO84_04130	COG1525	nuclease
CDO84_04130	COG4085	toxin activity
CDO84_04135	COG3764	Sortase (surface protein transpeptidase)
CDO84_04140	COG0564	pseudouridine synthase activity
CDO84_04150	COG0517	IMP dehydrogenase activity
CDO84_04155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO84_04160	COG3153	acetyltransferase
CDO84_04160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO84_04165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO84_04170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CDO84_04175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CDO84_04180	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CDO84_04185	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CDO84_04190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDO84_04195	COG2203	Gaf domain
CDO84_04195	COG4585	Histidine kinase
CDO84_04200	COG2197	response regulator
CDO84_04205	COG0431	NADPH-dependent FMN reductase
CDO84_04220	COG0791	NLP P60 protein
CDO84_04220	COG1388	LysM domain
CDO84_04225	COG1959	2 iron, 2 sulfur cluster binding
CDO84_04230	COG0668	transmembrane transport
CDO84_04235	COG2719	SpoVR family
CDO84_04240	COG1785	Belongs to the alkaline phosphatase family
CDO84_04245	COG0791	NLP P60 protein
CDO84_04245	COG1388	LysM domain
CDO84_04250	COG0583	DNA-binding transcription factor activity
CDO84_04255	COG0372	Belongs to the citrate synthase family
CDO84_04260	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_04265	COG0531	amino acid
CDO84_04270	COG0733	neurotransmitter:sodium symporter activity
CDO84_04275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_04280	COG0456	acetyltransferase
CDO84_04295	COG1595	DNA-templated transcription, initiation
CDO84_04300	COG0667	Aldo Keto reductase
CDO84_04305	COG0204	Acyl-transferase
CDO84_04310	COG1253	flavin adenine dinucleotide binding
CDO84_04315	COG0789	Transcriptional regulator
CDO84_04320	COG0436	Aminotransferase
CDO84_04325	COG1253	flavin adenine dinucleotide binding
CDO84_04330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDO84_04335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDO84_04340	COG0584	glycerophosphoryl diester phosphodiesterase
CDO84_04350	COG0668	transmembrane transport
CDO84_04355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CDO84_04360	COG0726	polysaccharide deacetylase
CDO84_04365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO84_04370	COG1757	Na H antiporter
CDO84_04375	COG0589	response to stress
CDO84_04385	COG1132	(ABC) transporter
CDO84_04390	COG1132	(ABC) transporter
CDO84_04395	COG0702	epimerase
CDO84_04415	COG0189	ligase activity
CDO84_04420	COG0189	ligase activity
CDO84_04425	COG4399	Belongs to the UPF0754 family
CDO84_04430	COG3679	Belongs to the UPF0342 family
CDO84_04435	COG4335	DNA alkylation repair
CDO84_04440	COG0561	phosphatase activity
CDO84_04445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO84_04450	COG0475	glutathione-regulated potassium exporter activity
CDO84_04455	COG0490	domain, Protein
CDO84_04465	COG1024	Enoyl-CoA hydratase
CDO84_04475	COG4152	abc transporter atp-binding protein
CDO84_04480	COG1668	transmembrane transport
CDO84_04485	COG0420	3'-5' exonuclease activity
CDO84_04490	COG4717	serine-type aminopeptidase activity
CDO84_04495	COG3481	metal-dependent phosphohydrolase, HD sub domain
CDO84_04505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO84_04535	COG1846	Transcriptional regulator
CDO84_04540	COG4980	gas vesicle protein
CDO84_04555	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CDO84_04560	COG0537	adenosine 5'-monophosphoramidase activity
CDO84_04565	COG1131	(ABC) transporter
CDO84_04570	COG4473	ABC transporter
CDO84_04580	COG1473	amidohydrolase
CDO84_04585	COG3069	C4-dicarboxylate transmembrane transporter activity
CDO84_04595	COG2329	Antibiotic biosynthesis monooxygenase
CDO84_04600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO84_04605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDO84_04620	COG1309	transcriptional regulator
CDO84_04625	COG1511	domain protein
CDO84_04630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO84_04635	COG4377	Putative membrane peptidase family (DUF2324)
CDO84_04645	COG1363	Peptidase, m42
CDO84_04650	COG4405	Protein conserved in bacteria
CDO84_04655	COG1301	dicarboxylic acid transport
CDO84_04665	COG1234	tRNA 3'-trailer cleavage
CDO84_04670	COG0095	Lipoate-protein ligase
CDO84_04675	COG0702	epimerase
CDO84_04680	COG0318	PFAM AMP-dependent synthetase and ligase
CDO84_04690	COG0501	Belongs to the peptidase M48B family
CDO84_04700	COG0456	acetyltransferase
CDO84_04705	COG0604	alcohol dehydrogenase
CDO84_04710	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CDO84_04715	COG0406	alpha-ribazole phosphatase activity
CDO84_04720	COG0183	Belongs to the thiolase family
CDO84_04725	COG0318	PFAM AMP-dependent synthetase and ligase
CDO84_04730	COG1268	BioY protein
CDO84_04735	COG0840	transmembrane signaling receptor activity
CDO84_04740	COG0723	plastoquinol--plastocyanin reductase activity
CDO84_04740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO84_04745	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_04755	COG4903	ComK protein
CDO84_04770	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_04780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDO84_04795	COG0398	Pfam SNARE associated Golgi protein
CDO84_04800	COG0681	Belongs to the peptidase S26 family
CDO84_04805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDO84_04810	COG1846	Transcriptional regulator
CDO84_04815	COG3180	Ammonia monooxygenase
CDO84_04820	COG2814	Major facilitator Superfamily
CDO84_04820	COG0477	Major facilitator Superfamily
CDO84_04825	COG4533	DNA binding
CDO84_04835	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CDO84_04840	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CDO84_04845	COG1074	ATP-dependent DNA helicase activity
CDO84_04850	COG0420	3'-5' exonuclease activity
CDO84_04855	COG0419	ATPase involved in DNA repair
CDO84_04860	COG1403	HNH endonuclease
CDO84_04900	COG5337	Spore coat protein CotH
CDO84_04905	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDO84_04915	COG1404	Belongs to the peptidase S8 family
CDO84_04925	COG0367	asparagine synthase
CDO84_04930	COG1562	ergosterol biosynthetic process
CDO84_04935	COG0534	Mate efflux family protein
CDO84_04940	COG1917	Cupin 2, conserved barrel domain protein
CDO84_04940	COG2207	Transcriptional regulator
CDO84_04945	COG1609	Transcriptional regulator
CDO84_04950	COG0673	inositol 2-dehydrogenase activity
CDO84_04955	COG2318	DinB family
CDO84_04960	COG1279	arginine transmembrane transporter activity
CDO84_04965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CDO84_04970	COG1357	PFAM Pentapeptide repeats (8 copies)
CDO84_04975	COG2267	carboxylic ester hydrolase activity
CDO84_04980	COG0529	Catalyzes the synthesis of activated sulfate
CDO84_04985	COG2046	Belongs to the sulfate adenylyltransferase family
CDO84_04990	COG0175	sulfate reduction
CDO84_04995	COG2045	Belongs to the ComB family
CDO84_05000	COG1809	phosphosulfolactate synthase activity
CDO84_05005	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDO84_05010	COG4948	Mandelate Racemase Muconate Lactonizing
CDO84_05015	COG2814	Major facilitator Superfamily
CDO84_05020	COG0454	-acetyltransferase
CDO84_05025	COG2153	protein acetylation
CDO84_05030	COG0646	methionine synthase
CDO84_05030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CDO84_05035	COG1666	GTP binding
CDO84_05040	COG2996	Protein conserved in bacteria
CDO84_05060	COG1695	Transcriptional regulator
CDO84_05075	COG3227	Zinc metalloprotease (Elastase)
CDO84_05080	COG1307	EDD domain protein, DegV family
CDO84_05085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDO84_05100	COG0561	phosphatase activity
CDO84_05105	COG1073	alpha beta
CDO84_05110	COG2151	metal-sulfur cluster biosynthetic enzyme
CDO84_05120	COG0277	FAD linked oxidase domain protein
CDO84_05125	COG2271	Major facilitator Superfamily
CDO84_05130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDO84_05145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO84_05150	COG0505	Belongs to the CarA family
CDO84_05155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDO84_05160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDO84_05175	COG2267	carboxylic ester hydrolase activity
CDO84_05185	COG1744	ABC transporter substrate-binding protein PnrA-like
CDO84_05200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO84_05205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO84_05210	COG5504	Zn-dependent protease
CDO84_05215	COG0444	Belongs to the ABC transporter superfamily
CDO84_05220	COG4608	Belongs to the ABC transporter superfamily
CDO84_05230	COG0601	transmembrane transport
CDO84_05235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO84_05245	COG0180	Tryptophanyl-tRNA synthetase
CDO84_05250	COG4166	transmembrane transport
CDO84_05255	COG0601	transmembrane transport
CDO84_05260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO84_05265	COG0444	Belongs to the ABC transporter superfamily
CDO84_05270	COG4608	Belongs to the ABC transporter superfamily
CDO84_05275	COG2814	Major facilitator Superfamily
CDO84_05280	COG0456	acetyltransferase
CDO84_05285	COG1393	Belongs to the ArsC family
CDO84_05290	COG0861	Integral membrane protein TerC family
CDO84_05295	COG4862	establishment of competence for transformation
CDO84_05300	COG4469	Competence protein
CDO84_05305	COG1164	Oligoendopeptidase f
CDO84_05325	COG2346	COG2346, Truncated hemoglobins
CDO84_05330	COG0741	lytic transglycosylase activity
CDO84_05335	COG4116	CYTH
CDO84_05345	COG2357	RelA SpoT domain protein
CDO84_05350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDO84_05355	COG0564	pseudouridine synthase activity
CDO84_05360	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDO84_05365	COG0475	glutathione-regulated potassium exporter activity
CDO84_05365	COG0569	domain protein
CDO84_05370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CDO84_05375	COG0352	thiamine-phosphate diphosphorylase activity
CDO84_05380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO84_05385	COG2104	thiamine diphosphate biosynthetic process
CDO84_05390	COG2022	thiamine diphosphate biosynthetic process
CDO84_05395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDO84_05400	COG0351	phosphomethylpyrimidine kinase
CDO84_05405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDO84_05460	COG0210	DNA helicase
CDO84_05470	COG2153	protein acetylation
CDO84_05475	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CDO84_05480	COG2382	esterase
CDO84_05485	COG0626	cystathionine gamma-synthase activity
CDO84_05490	COG0626	cystathionine gamma-synthase activity
CDO84_05495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_05500	COG5505	Protein of unknown function (DUF819)
CDO84_05525	COG5444	nuclease activity
CDO84_05540	COG0457	Tetratricopeptide repeat
CDO84_05545	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CDO84_05555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_05555	COG3711	transcriptional antiterminator
CDO84_05560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO84_05560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_05560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO84_05565	COG1482	cell wall glycoprotein biosynthetic process
CDO84_05575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_05585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDO84_05605	COG0109	protoheme IX farnesyltransferase activity
CDO84_05615	COG0726	polysaccharide deacetylase
CDO84_05630	COG5504	Zn-dependent protease
CDO84_05635	COG2205	protein histidine kinase activity
CDO84_05645	COG3383	formate dehydrogenase (NAD+) activity
CDO84_05650	COG2427	Protein of unknown function (DUF1641)
CDO84_05660	COG1051	belongs to the nudix hydrolase family
CDO84_05670	COG2124	cytochrome p450
CDO84_05675	COG1819	glycosyl
CDO84_05685	COG1587	Uroporphyrinogen-III synthase
CDO84_05690	COG0390	transport system, permease component
CDO84_05695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDO84_05700	COG0697	spore germination
CDO84_05705	COG4297	protein containing double-stranded beta helix domain
CDO84_05715	COG1252	NADH dehydrogenase
CDO84_05720	COG1904	glucuronate isomerase
CDO84_05725	COG2211	Major facilitator Superfamily
CDO84_05730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CDO84_05735	COG1063	alcohol dehydrogenase
CDO84_05740	COG1312	Catalyzes the dehydration of D-mannonate
CDO84_05745	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_05750	COG2271	Major facilitator Superfamily
CDO84_05755	COG1609	Transcriptional regulator
CDO84_05760	COG0246	Mannitol dehydrogenase
CDO84_05765	COG2721	sulfolactate sulfo-lyase activity
CDO84_05770	COG0730	response to heat
CDO84_05775	COG2318	DinB family
CDO84_05780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO84_05785	COG0457	Tetratricopeptide repeat
CDO84_05795	COG2350	Protein conserved in bacteria
CDO84_05800	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_05800	COG5632	N-Acetylmuramoyl-L-alanine amidase
CDO84_05800	COG1388	LysM domain
CDO84_05810	COG4195	phage-related replication protein
CDO84_05815	COG3546	catalase activity
CDO84_05820	COG2856	Zn peptidase
CDO84_05825	COG1396	sequence-specific DNA binding
CDO84_05835	COG1522	sequence-specific DNA binding
CDO84_05840	COG1484	DNA-dependent DNA replication
CDO84_05860	COG1595	DNA-templated transcription, initiation
CDO84_05865	COG3728	DNA packaging
CDO84_05865	COG5484	DNA packaging
CDO84_05870	COG1783	phage Terminase large subunit
CDO84_05875	COG5518	Phage portal protein
CDO84_05880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CDO84_05885	COG4653	Phage capsid family
CDO84_05935	COG5412	phage tail tape measure protein
CDO84_05935	COG3953	SLT domain
CDO84_05940	COG1652	LysM domain
CDO84_05945	COG4193	domain, Protein
CDO84_05955	COG3628	GPW Gp25 family protein
CDO84_05960	COG3299	homolog of phage Mu protein gp47
CDO84_05965	COG3778	Protein conserved in bacteria
CDO84_06005	COG5632	N-Acetylmuramoyl-L-alanine amidase
CDO84_06005	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_06020	COG0306	phosphate transporter
CDO84_06025	COG1392	Phosphate transport regulator
CDO84_06030	COG0531	amino acid
CDO84_06035	COG0346	lactoylglutathione lyase activity
CDO84_06040	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO84_06045	COG0463	Glycosyl transferase, family 2
CDO84_06050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO84_06055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO84_06060	COG2362	D-Aminopeptidase
CDO84_06065	COG0601	transmembrane transport
CDO84_06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDO84_06075	COG0444	Belongs to the ABC transporter superfamily
CDO84_06080	COG4166	transmembrane transport
CDO84_06085	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDO84_06090	COG4948	Mandelate Racemase Muconate Lactonizing
CDO84_06095	COG0791	NLP P60 protein
CDO84_06100	COG4608	Belongs to the ABC transporter superfamily
CDO84_06105	COG2706	6-phosphogluconolactonase activity
CDO84_06110	COG1834	amidinotransferase
CDO84_06115	COG1607	acyl-coa hydrolase
CDO84_06120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDO84_06120	COG1017	nitric oxide dioxygenase activity
CDO84_06130	COG2323	membrane
CDO84_06135	COG2318	DinB family
CDO84_06140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_06145	COG2076	Multidrug Resistance protein
CDO84_06150	COG2076	Multidrug Resistance protein
CDO84_06155	COG0788	formyltetrahydrofolate deformylase activity
CDO84_06160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDO84_06165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDO84_06170	COG1764	response to oxidative stress
CDO84_06175	COG1846	Transcriptional regulator
CDO84_06180	COG1764	response to oxidative stress
CDO84_06190	COG0590	tRNA wobble adenosine to inosine editing
CDO84_06195	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDO84_06200	COG1404	Belongs to the peptidase S8 family
CDO84_06205	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_06210	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDO84_06215	COG1122	ATPase activity
CDO84_06220	COG4721	ABC-type cobalt transport system, permease component
CDO84_06230	COG0745	RESPONSE REGULATOR receiver
CDO84_06235	COG5002	protein histidine kinase activity
CDO84_06235	COG3850	Histidine kinase
CDO84_06240	COG3212	peptidase
CDO84_06245	COG3212	peptidase
CDO84_06255	COG2239	Acts as a magnesium transporter
CDO84_06260	COG0789	Transcriptional regulator
CDO84_06275	COG1846	Transcriptional regulator
CDO84_06280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDO84_06285	COG0726	polysaccharide deacetylase
CDO84_06290	COG1408	metallophosphoesterase
CDO84_06300	COG0463	Glycosyl transferase, family 2
CDO84_06305	COG3285	dna ligase
CDO84_06305	COG1793	dna ligase
CDO84_06310	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CDO84_06315	COG3300	MHYT domain
CDO84_06315	COG5001	Diguanylate cyclase
CDO84_06320	COG0586	Pfam SNARE associated Golgi protein
CDO84_06325	COG0861	Integral membrane protein TerC family
CDO84_06330	COG1191	sigma factor activity
CDO84_06350	COG0501	Belongs to the peptidase M48B family
CDO84_06355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDO84_06370	COG3594	Acyltransferase
CDO84_06375	COG5002	protein histidine kinase activity
CDO84_06380	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CDO84_06385	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CDO84_06390	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CDO84_06395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDO84_06400	COG0436	Aminotransferase
CDO84_06405	COG1850	ribulose-bisphosphate carboxylase activity
CDO84_06410	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CDO84_06415	COG0235	Class ii aldolase
CDO84_06420	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CDO84_06425	COG3339	Conserved Protein
CDO84_06440	COG3852	Histidine kinase
CDO84_06445	COG1846	Transcriptional regulator
CDO84_06450	COG1360	Flagellar Motor Protein
CDO84_06455	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDO84_06460	COG0542	response to heat
CDO84_06465	COG3949	Membrane
CDO84_06470	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDO84_06475	COG0720	synthase
CDO84_06480	COG0602	queuosine metabolic process
CDO84_06485	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDO84_06520	COG4873	Protein conserved in bacteria
CDO84_06530	COG3773	Cell wall hydrolase
CDO84_06535	COG2244	polysaccharide biosynthetic process
CDO84_06540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_06545	COG2217	Heavy metal translocating P-type atpase
CDO84_06555	COG0006	proline dipeptidase activity
CDO84_06560	COG1609	Transcriptional regulator
CDO84_06565	COG3711	transcriptional antiterminator
CDO84_06570	COG1263	PTS System
CDO84_06570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_06570	COG2190	(PTS) system
CDO84_06575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_06580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDO84_06590	COG1533	DNA photolyase activity
CDO84_06595	COG0456	acetyltransferase
CDO84_06600	COG0840	transmembrane signaling receptor activity
CDO84_06605	COG2084	Dehydrogenase
CDO84_06610	COG4257	antibiotic catabolic process
CDO84_06615	COG2340	Cysteine-rich secretory protein family
CDO84_06620	COG0768	penicillin binding
CDO84_06625	COG4191	Histidine kinase
CDO84_06630	COG0436	Aminotransferase
CDO84_06640	COG0835	chemotaxis
CDO84_06640	COG0784	Response regulator, receiver
CDO84_06650	COG2814	Major facilitator Superfamily
CDO84_06655	COG1376	ErfK ybiS ycfS ynhG family protein
CDO84_06660	COG1408	metallophosphoesterase
CDO84_06665	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_06670	COG2200	EAL domain
CDO84_06675	COG4703	Protein of unknown function (DUF1797)
CDO84_06680	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CDO84_06690	COG0517	IMP dehydrogenase activity
CDO84_06695	COG0583	DNA-binding transcription factor activity
CDO84_06700	COG0716	FMN binding
CDO84_06710	COG0716	FMN binding
CDO84_06715	COG2171	N-acyltransferase activity
CDO84_06720	COG1473	amidohydrolase
CDO84_06730	COG0668	transmembrane transport
CDO84_06735	COG0450	alkyl hydroperoxide reductase
CDO84_06740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_06755	COG0746	molybdenum cofactor guanylyltransferase activity
CDO84_06760	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CDO84_06765	COG0303	'Molybdopterin
CDO84_06770	COG1763	Mo-molybdopterin cofactor biosynthetic process
CDO84_06775	COG0314	molybdopterin synthase activity
CDO84_06780	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CDO84_06785	COG1132	(ABC) transporter
CDO84_06790	COG1132	(ABC) transporter
CDO84_06800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO84_06805	COG1136	(ABC) transporter
CDO84_06810	COG0577	efflux transmembrane transporter activity
CDO84_06815	COG1349	DNA-binding transcription factor activity
CDO84_06820	COG1105	Belongs to the carbohydrate kinase PfkB family
CDO84_06825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_06825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO84_06825	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CDO84_06830	COG0681	Belongs to the peptidase S26 family
CDO84_06840	COG0488	(ABC) transporter
CDO84_06845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDO84_06850	COG2309	aminopeptidase activity
CDO84_06860	COG1077	Cell shape determining protein MreB Mrl
CDO84_06865	COG2002	toxin-antitoxin pair type II binding
CDO84_06870	COG3852	Histidine kinase
CDO84_06875	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CDO84_06875	COG2105	PFAM AIG2 family protein
CDO84_06880	COG0569	domain protein
CDO84_06885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CDO84_06890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDO84_06900	COG0561	phosphatase activity
CDO84_06905	COG0242	peptide deformylase activity
CDO84_06915	COG0497	DNA recombination
CDO84_06920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO84_06925	COG0022	dehydrogenase e1 component
CDO84_06930	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO84_06935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO84_06940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_06950	COG1982	Orn Lys Arg decarboxylase major
CDO84_06955	COG4476	Belongs to the UPF0223 family
CDO84_06960	COG4493	Belongs to the UPF0637 family
CDO84_06970	COG0483	inositol monophosphate 1-phosphatase activity
CDO84_06980	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CDO84_07000	COG1595	DNA-templated transcription, initiation
CDO84_07030	COG4896	Protein conserved in bacteria
CDO84_07040	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CDO84_07045	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO84_07050	COG2066	Belongs to the glutaminase family
CDO84_07055	COG4838	Belongs to the UPF0358 family
CDO84_07060	COG0772	Belongs to the SEDS family
CDO84_07065	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CDO84_07070	COG1612	heme a metabolic process
CDO84_07075	COG0109	protoheme IX farnesyltransferase activity
CDO84_07080	COG2010	Cytochrome c
CDO84_07080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO84_07085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO84_07090	COG1845	cytochrome c oxidase, subunit III
CDO84_07095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDO84_07100	COG3336	cytochrome c oxidase
CDO84_07110	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CDO84_07115	COG2340	Cysteine-rich secretory protein family
CDO84_07130	COG3679	Belongs to the UPF0342 family
CDO84_07135	COG4471	UPF0298 protein
CDO84_07140	COG0742	ribosomal rna small subunit methyltransferase
CDO84_07145	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDO84_07150	COG3314	Sporulation integral membrane protein YlbJ
CDO84_07155	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO84_07160	COG3480	Lon protease (S16) C-terminal proteolytic domain
CDO84_07165	COG1323	Belongs to the UPF0348 family
CDO84_07175	COG1399	metal-binding, possibly nucleic acid-binding protein
CDO84_07180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDO84_07190	COG0454	-acetyltransferase
CDO84_07195	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CDO84_07200	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CDO84_07205	COG2001	Belongs to the MraZ family
CDO84_07210	COG0275	rRNA processing
CDO84_07215	COG4839	cell division protein FtsL
CDO84_07225	COG0768	penicillin binding
CDO84_07230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDO84_07235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO84_07240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDO84_07245	COG0772	Belongs to the SEDS family
CDO84_07250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDO84_07255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDO84_07260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CDO84_07265	COG3879	Bacterial protein of unknown function (DUF881)
CDO84_07270	COG3879	Bacterial protein of unknown function (DUF881)
CDO84_07275	COG3856	small basic protein
CDO84_07280	COG0849	cell division
CDO84_07285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDO84_07290	COG4412	M6 family metalloprotease domain protein
CDO84_07290	COG1404	Belongs to the peptidase S8 family
CDO84_07300	COG1191	sigma factor activity
CDO84_07305	COG1191	sigma factor activity
CDO84_07310	COG1119	ATPase activity
CDO84_07315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO84_07320	COG1873	PFAM PRC-barrel domain
CDO84_07330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDO84_07335	COG1799	cell septum assembly
CDO84_07340	COG0762	integral membrane protein
CDO84_07345	COG2302	S4 RNA-binding domain
CDO84_07350	COG3599	regulation of cell shape
CDO84_07355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDO84_07360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDO84_07365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDO84_07370	COG0564	pseudouridine synthase activity
CDO84_07375	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CDO84_07380	COG2233	PERMEase
CDO84_07385	COG0540	Belongs to the ATCase OTCase family
CDO84_07390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO84_07395	COG0505	Belongs to the CarA family
CDO84_07400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDO84_07405	COG0543	2 iron, 2 sulfur cluster binding
CDO84_07410	COG0167	dihydroorotate dehydrogenase activity
CDO84_07415	COG0284	orotidine-5'-phosphate decarboxylase activity
CDO84_07420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDO84_07425	COG0175	sulfate reduction
CDO84_07430	COG0306	phosphate transporter
CDO84_07435	COG2046	Belongs to the sulfate adenylyltransferase family
CDO84_07440	COG0529	Catalyzes the synthesis of activated sulfate
CDO84_07445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDO84_07450	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CDO84_07455	COG1648	precorrin-2 dehydrogenase activity
CDO84_07465	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDO84_07470	COG1561	YicC-like family, N-terminal region
CDO84_07475	COG2052	Domain of unknown function (DUF370)
CDO84_07480	COG0194	GDP metabolic process
CDO84_07485	COG1758	RNA polymerase activity
CDO84_07490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDO84_07495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDO84_07500	COG0242	peptide deformylase activity
CDO84_07505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDO84_07510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO84_07510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDO84_07515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDO84_07520	COG0631	protein serine/threonine phosphatase activity
CDO84_07525	COG2815	serine threonine protein kinase
CDO84_07525	COG0515	serine threonine protein kinase
CDO84_07530	COG1162	GTPase activity
CDO84_07535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDO84_07540	COG1564	THIamine pyrophosphokinase
CDO84_07550	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDO84_07555	COG1302	Protein conserved in bacteria
CDO84_07560	COG1461	Dihydroxyacetone kinase
CDO84_07565	COG1760	l-serine dehydratase
CDO84_07570	COG1760	l-serine dehydratase
CDO84_07575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDO84_07580	COG1349	DNA-binding transcription factor activity
CDO84_07580	COG2050	protein possibly involved in aromatic compounds catabolism
CDO84_07585	COG0416	fatty acid biosynthetic process
CDO84_07590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDO84_07595	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_07600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO84_07605	COG0571	ribonuclease III activity
CDO84_07610	COG1196	nuclear chromosome segregation
CDO84_07615	COG0552	protein localization to endoplasmic reticulum
CDO84_07625	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CDO84_07630	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDO84_07635	COG0228	four-way junction DNA binding
CDO84_07640	COG1837	Belongs to the UPF0109 family
CDO84_07650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDO84_07655	COG0336	Belongs to the RNA methyltransferase TrmD family
CDO84_07660	COG0335	large ribosomal subunit rRNA binding
CDO84_07665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CDO84_07670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDO84_07680	COG2257	FlhB HrpN YscU SpaS Family
CDO84_07685	COG0045	succinate-CoA ligase (ADP-forming) activity
CDO84_07690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CDO84_07695	COG0758	DNA mediated transformation
CDO84_07700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDO84_07705	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CDO84_07710	COG4974	Belongs to the 'phage' integrase family
CDO84_07715	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CDO84_07720	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CDO84_07725	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CDO84_07730	COG1815	bacterial-type flagellum-dependent cell motility
CDO84_07735	COG1558	bacterial-type flagellum-dependent cell motility
CDO84_07740	COG1677	Flagellar hook-basal body complex protein FliE
CDO84_07745	COG1766	The M ring may be actively involved in energy transduction
CDO84_07750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO84_07755	COG1317	bacterial-type flagellum organization
CDO84_07760	COG1157	protein secretion by the type III secretion system
CDO84_07765	COG2882	bacterial-type flagellum organization
CDO84_07770	COG3334	PFAM MgtE intracellular
CDO84_07775	COG3144	bacterial-type flagellum assembly
CDO84_07780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CDO84_07785	COG4786	Flagellar basal body rod
CDO84_07790	COG1582	Flagellar protein (FlbD)
CDO84_07795	COG1580	Controls the rotational direction of flagella during chemotaxis
CDO84_07800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO84_07805	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CDO84_07805	COG1776	CheC inhibitor of MCP methylation
CDO84_07810	COG2201	protein-glutamate methylesterase activity
CDO84_07815	COG3190	flagellar
CDO84_07820	COG1338	Plays a role in the flagellum-specific transport system
CDO84_07825	COG1987	bacterial-type flagellum assembly
CDO84_07830	COG1684	flagellar biosynthetic protein fliR
CDO84_07835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO84_07840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CDO84_07845	COG1419	protein localization to endoplasmic reticulum
CDO84_07850	COG0455	bacterial-type flagellum organization
CDO84_07855	COG2201	protein-glutamate methylesterase activity
CDO84_07860	COG2198	Histidine kinase
CDO84_07860	COG0643	Histidine kinase
CDO84_07865	COG0835	chemotaxis
CDO84_07870	COG1776	CheC inhibitor of MCP methylation
CDO84_07875	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CDO84_07880	COG1191	sigma factor activity
CDO84_07890	COG0052	Belongs to the universal ribosomal protein uS2 family
CDO84_07895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDO84_07900	COG0528	UMP kinase activity
CDO84_07905	COG0233	cytoplasmic translational termination
CDO84_07910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDO84_07915	COG4589	Belongs to the CDS family
CDO84_07920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDO84_07925	COG0750	zinc metalloprotease
CDO84_07930	COG0442	prolyl-tRNA aminoacylation
CDO84_07935	COG2176	DNA-directed DNA polymerase activity
CDO84_07940	COG0779	Required for maturation of 30S ribosomal subunits
CDO84_07945	COG0195	Participates in both transcription termination and antitermination
CDO84_07950	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CDO84_07955	COG1358	cellular component organization or biogenesis
CDO84_07960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDO84_07965	COG1550	Protein conserved in bacteria
CDO84_07970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDO84_07975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDO84_07980	COG0196	riboflavin kinase activity
CDO84_07985	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDO84_07990	COG1185	polyribonucleotide nucleotidyltransferase activity
CDO84_07995	COG0726	polysaccharide deacetylase
CDO84_08000	COG0612	Peptidase, M16
CDO84_08005	COG1873	PFAM PRC-barrel domain
CDO84_08010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO84_08015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDO84_08020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDO84_08025	COG0527	aspartate kinase activity
CDO84_08030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDO84_08035	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDO84_08040	COG0740	serine-type endopeptidase activity
CDO84_08050	COG4980	gas vesicle protein
CDO84_08050	COG1674	ftsk spoiiie
CDO84_08055	COG2188	Transcriptional regulator
CDO84_08060	COG2814	Major facilitator Superfamily
CDO84_08065	COG0612	Peptidase, M16
CDO84_08070	COG0612	Peptidase, M16
CDO84_08075	COG0300	oxidoreductase activity
CDO84_08090	COG1426	Protein conserved in bacteria
CDO84_08095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDO84_08100	COG1546	Belongs to the CinA family
CDO84_08100	COG1058	Belongs to the CinA family
CDO84_08105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDO84_08110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDO84_08115	COG1418	mRNA catabolic process
CDO84_08120	COG1692	metallophosphoesterase
CDO84_08125	COG2359	stage V sporulation protein S
CDO84_08130	COG1063	alcohol dehydrogenase
CDO84_08135	COG0156	8-amino-7-oxononanoate synthase activity
CDO84_08140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO84_08145	COG4550	Control of competence regulator ComK, YlbF/YmcA
CDO84_08155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDO84_08160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDO84_08205	COG3226	Transcriptional regulator
CDO84_08210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_08220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDO84_08225	COG3321	synthase
CDO84_08230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDO84_08230	COG2070	2-Nitropropane dioxygenase
CDO84_08235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO84_08240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDO84_08245	COG3425	synthase
CDO84_08250	COG1024	Enoyl-CoA hydratase
CDO84_08255	COG1024	Enoyl-CoA hydratase
CDO84_08260	COG3321	synthase
CDO84_08260	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_08260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08260	COG0318	PFAM AMP-dependent synthetase and ligase
CDO84_08260	COG0300	oxidoreductase activity
CDO84_08265	COG4221	oxidoreductase activity
CDO84_08265	COG3321	synthase
CDO84_08265	COG0300	oxidoreductase activity
CDO84_08265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO84_08270	COG3321	synthase
CDO84_08270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO84_08270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08270	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_08270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO84_08275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08275	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_08275	COG3321	synthase
CDO84_08275	COG4221	oxidoreductase activity
CDO84_08280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO84_08280	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CDO84_08280	COG3321	synthase
CDO84_08280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDO84_08285	COG2124	cytochrome p450
CDO84_08295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_08300	COG1404	Belongs to the peptidase S8 family
CDO84_08310	COG4195	phage-related replication protein
CDO84_08315	COG1764	response to oxidative stress
CDO84_08320	COG2076	Multidrug Resistance protein
CDO84_08325	COG2076	Multidrug Resistance protein
CDO84_08340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDO84_08345	COG1923	regulation of RNA biosynthetic process
CDO84_08360	COG1780	Probably involved in ribonucleotide reductase function
CDO84_08365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO84_08370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CDO84_08375	COG4112	unkown
CDO84_08380	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO84_08390	COG0464	growth
CDO84_08395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CDO84_08400	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CDO84_08405	COG0789	Transcriptional regulator
CDO84_08410	COG0174	glutamine synthetase
CDO84_08430	COG5444	nuclease activity
CDO84_08455	COG5444	nuclease activity
CDO84_08460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO84_08470	COG0457	Tetratricopeptide repeat
CDO84_08475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_08490	COG0135	phosphoribosylanthranilate isomerase activity
CDO84_08495	COG2211	Major facilitator Superfamily
CDO84_08500	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO84_08510	COG2115	Belongs to the xylose isomerase family
CDO84_08515	COG1070	Carbohydrate kinase
CDO84_08525	COG1525	nuclease
CDO84_08530	COG2814	Major facilitator Superfamily
CDO84_08535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDO84_08545	COG0756	dUTP diphosphatase activity
CDO84_08555	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CDO84_08585	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDO84_08595	COG3832	glyoxalase III activity
CDO84_08630	COG4195	phage-related replication protein
CDO84_08640	COG0346	lactoylglutathione lyase activity
CDO84_08650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CDO84_08655	COG1388	LysM domain
CDO84_08660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDO84_08665	COG4224	UPF0291 protein
CDO84_08670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO84_08680	COG3763	UPF0154 protein
CDO84_08690	COG0785	Cytochrome C biogenesis protein
CDO84_08695	COG2201	protein-glutamate methylesterase activity
CDO84_08700	COG4846	Membrane protein involved in cytochrome C biogenesis
CDO84_08710	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO84_08725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CDO84_08730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_08750	COG0824	Thioesterase
CDO84_08760	COG4841	protein insertion into membrane
CDO84_08765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDO84_08770	COG1832	CoA-binding protein
CDO84_08775	COG0187	DNA topoisomerase II activity
CDO84_08780	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO84_08790	COG1115	amino acid carrier protein
CDO84_08805	COG5520	Belongs to the glycosyl hydrolase 30 family
CDO84_08810	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO84_08815	COG2246	polysaccharide biosynthetic process
CDO84_08820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO84_08825	COG0586	Pfam SNARE associated Golgi protein
CDO84_08830	COG2404	hydrolase activity, acting on ester bonds
CDO84_08835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO84_08840	COG1024	Enoyl-CoA hydratase
CDO84_08845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO84_08850	COG0511	ligase activity, forming carbon-carbon bonds
CDO84_08855	COG0439	Biotin carboxylase
CDO84_08860	COG0318	PFAM AMP-dependent synthetase and ligase
CDO84_08865	COG1960	acyl-CoA dehydrogenase activity
CDO84_08885	COG1649	PFAM Uncharacterised BCR, COG1649
CDO84_08895	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CDO84_08895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_08920	COG2027	D-alanyl-D-alanine carboxypeptidase
CDO84_08925	COG2017	converts alpha-aldose to the beta-anomer
CDO84_08930	COG0534	Mate efflux family protein
CDO84_08945	COG0582	viral genome integration into host DNA
CDO84_08950	COG0166	Belongs to the GPI family
CDO84_08955	COG0405	Gamma-glutamyltransferase
CDO84_08960	COG0583	DNA-binding transcription factor activity
CDO84_08965	COG0604	alcohol dehydrogenase
CDO84_08970	COG0493	'glutamate synthase
CDO84_08975	COG0069	glutamate synthase activity
CDO84_08975	COG0067	glutamate synthase
CDO84_08975	COG0070	glutamate synthase
CDO84_08980	COG0583	DNA-binding transcription factor activity
CDO84_08985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDO84_08990	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO84_09000	COG0300	oxidoreductase activity
CDO84_09005	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CDO84_09015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CDO84_09030	COG2814	Major facilitator Superfamily
CDO84_09035	COG1070	Carbohydrate kinase
CDO84_09040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO84_09045	COG0243	molybdopterin cofactor binding
CDO84_09070	COG0840	transmembrane signaling receptor activity
CDO84_09070	COG5278	phosphoserine phosphatase activity
CDO84_09075	COG2368	4-hydroxyphenylacetate
CDO84_09080	COG4305	rare lipoprotein A
CDO84_09085	COG3619	membrane
CDO84_09090	COG3866	Pectate lyase
CDO84_09095	COG2135	peptidase activity
CDO84_09100	COG2140	Oxalate decarboxylase
CDO84_09110	COG0456	acetyltransferase
CDO84_09125	COG2720	vancomycin resistance protein
CDO84_09140	COG3739	integral membrane protein
CDO84_09145	COG0583	DNA-binding transcription factor activity
CDO84_09150	COG0697	spore germination
CDO84_09175	COG0574	Belongs to the PEP-utilizing enzyme family
CDO84_09175	COG3848	Pyruvate phosphate dikinase
CDO84_09180	COG4282	regulation of fungal-type cell wall biogenesis
CDO84_09185	COG1231	oxidoreductase activity
CDO84_09190	COG5434	Belongs to the glycosyl hydrolase 28 family
CDO84_09195	COG0726	polysaccharide deacetylase
CDO84_09300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO84_09305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO84_09310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO84_09340	COG5444	nuclease activity
CDO84_09365	COG1136	(ABC) transporter
CDO84_09365	COG0577	efflux transmembrane transporter activity
CDO84_09380	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_09385	COG1733	regulation of RNA biosynthetic process
CDO84_09395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO84_09400	COG0662	Cupin 2, conserved barrel domain protein
CDO84_09400	COG2207	Transcriptional regulator
CDO84_09405	COG0456	acetyltransferase
CDO84_09410	COG1309	transcriptional regulator
CDO84_09415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_09420	COG3708	Transcriptional regulator
CDO84_09425	COG2378	regulation of single-species biofilm formation
CDO84_09435	COG0640	Transcriptional regulator
CDO84_09440	COG0741	lytic transglycosylase activity
CDO84_09445	COG2322	membrane
CDO84_09460	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDO84_09465	COG3239	Fatty acid desaturase
CDO84_09470	COG4585	Histidine kinase
CDO84_09475	COG2197	response regulator
CDO84_09480	COG3584	3D domain protein
CDO84_09480	COG1388	LysM domain
CDO84_09485	COG0514	ATP-dependent DNA helicase (RecQ)
CDO84_09500	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDO84_09505	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDO84_09520	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO84_09545	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_09550	COG1657	PFAM Prenyltransferase squalene oxidase
CDO84_09555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO84_09560	COG0733	neurotransmitter:sodium symporter activity
CDO84_09565	COG0385	Bile acid
CDO84_09570	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO84_09575	COG0567	Dehydrogenase, E1 component
CDO84_09580	COG4548	von Willebrand factor, type A
CDO84_09585	COG0714	Associated with various cellular activities
CDO84_09590	COG2032	superoxide dismutase activity
CDO84_09595	COG0791	NLP P60 protein
CDO84_09595	COG1388	LysM domain
CDO84_09600	COG1819	glycosyl
CDO84_09605	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CDO84_09610	COG0534	Mate efflux family protein
CDO84_09615	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_09620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDO84_09625	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDO84_09635	COG2962	Rard protein
CDO84_09655	COG1942	4-Oxalocrotonate Tautomerase
CDO84_09660	COG1733	regulation of RNA biosynthetic process
CDO84_09665	COG0778	Nitroreductase
CDO84_09670	COG0400	carboxylic ester hydrolase activity
CDO84_09675	COG0346	lactoylglutathione lyase activity
CDO84_09685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDO84_09690	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_09690	COG0793	Belongs to the peptidase S41A family
CDO84_09695	COG2226	methyltransferase
CDO84_09705	COG1876	peptidase activity
CDO84_09710	COG0813	purine-nucleoside phosphorylase activity
CDO84_09725	COG0671	phosphoesterase, PA-phosphatase related
CDO84_09745	COG4479	Belongs to the UPF0346 family
CDO84_09755	COG1509	lysine 2,3-aminomutase activity
CDO84_09760	COG0456	acetyltransferase
CDO84_09765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO84_09770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDO84_09775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDO84_09780	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO84_09790	COG0456	acetyltransferase
CDO84_09795	COG0463	Glycosyl transferase, family 2
CDO84_09810	COG4641	Protein conserved in bacteria
CDO84_09815	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
CDO84_09820	COG1086	Polysaccharide biosynthesis protein
CDO84_09825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO84_09830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDO84_09835	COG1846	Transcriptional regulator
CDO84_09840	COG0534	Mate efflux family protein
CDO84_09850	COG4698	Protein conserved in bacteria
CDO84_09855	COG2755	lipolytic protein G-D-S-L family
CDO84_09860	COG1999	signal sequence binding
CDO84_09870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CDO84_09875	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDO84_09880	COG1272	protein, Hemolysin III
CDO84_09885	COG0204	Acyl-transferase
CDO84_09890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDO84_09895	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDO84_09905	COG2136	Putative SAM-dependent methyltransferase
CDO84_09905	COG2521	methyltransferase
CDO84_09915	COG0129	dihydroxy-acid dehydratase activity
CDO84_09920	COG1413	lyase activity
CDO84_09925	COG1418	mRNA catabolic process
CDO84_09930	COG0386	Belongs to the glutathione peroxidase family
CDO84_09935	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CDO84_09940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDO84_09945	COG1278	Cold shock
CDO84_09965	COG0328	RNA-DNA hybrid ribonuclease activity
CDO84_09970	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CDO84_09975	COG0328	RNA-DNA hybrid ribonuclease activity
CDO84_09985	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO84_10000	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDO84_10005	COG1755	Isoprenylcysteine carboxyl methyltransferase
CDO84_10010	COG3424	synthase
CDO84_10015	COG2233	PERMEase
CDO84_10020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO84_10025	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CDO84_10035	COG0800	Aldolase
CDO84_10040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO84_10045	COG1609	Transcriptional regulator
CDO84_10050	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CDO84_10055	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_10060	COG1199	ATP-dependent helicase activity
CDO84_10075	COG0116	Belongs to the methyltransferase superfamily
CDO84_10090	COG4474	Belongs to the UPF0398 family
CDO84_10100	COG3359	exonuclease
CDO84_10105	COG1205	dead DEAH box helicase
CDO84_10105	COG1111	helicase
CDO84_10110	COG2190	(PTS) system
CDO84_10115	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO84_10150	COG3331	DNA recombination
CDO84_10155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO84_10155	COG4499	WXG100 protein secretion system (Wss), protein YukC
CDO84_10165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDO84_10170	COG3935	DnaD domain protein
CDO84_10175	COG0017	Asparaginyl-tRNA synthetase
CDO84_10180	COG0436	Aminotransferase
CDO84_10185	COG5353	protein conserved in bacteria
CDO84_10195	COG1199	ATP-dependent helicase activity
CDO84_10195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CDO84_10200	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CDO84_10205	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDO84_10210	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDO84_10215	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CDO84_10215	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CDO84_10220	COG0617	tRNA 3'-terminal CCA addition
CDO84_10225	COG0438	transferase activity, transferring glycosyl groups
CDO84_10230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CDO84_10235	COG1803	Methylglyoxal synthase
CDO84_10240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDO84_10245	COG1694	Mazg nucleotide pyrophosphohydrolase
CDO84_10250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDO84_10260	COG4347	Protein of unknown function (DUF1405)
CDO84_10265	COG2010	Cytochrome c
CDO84_10265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDO84_10270	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CDO84_10275	COG0723	plastoquinol--plastocyanin reductase activity
CDO84_10285	COG5582	Belongs to the UPF0302 family
CDO84_10290	COG0457	Tetratricopeptide repeat
CDO84_10295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDO84_10300	COG0287	Prephenate dehydrogenase
CDO84_10305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDO84_10310	COG0159	tryptophan synthase activity
CDO84_10315	COG0133	tryptophan synthase activity
CDO84_10320	COG0135	phosphoribosylanthranilate isomerase activity
CDO84_10330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDO84_10335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO84_10340	COG4401	Chorismate mutase type I
CDO84_10345	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDO84_10350	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDO84_10355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CDO84_10360	COG0105	UTP biosynthetic process
CDO84_10365	COG0142	geranyltranstransferase activity
CDO84_10370	COG2226	methyltransferase
CDO84_10375	COG0142	geranyltranstransferase activity
CDO84_10385	COG0302	gtp cyclohydrolase
CDO84_10390	COG0776	regulation of translation
CDO84_10395	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CDO84_10410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDO84_10415	COG1160	GTP binding
CDO84_10440	COG1304	FMN binding
CDO84_10445	COG0539	negative regulation of cytoplasmic translation
CDO84_10450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDO84_10460	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CDO84_10465	COG2959	enzyme of heme biosynthesis
CDO84_10470	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_10470	COG3773	Cell wall hydrolase
CDO84_10475	COG2339	peptidase activity
CDO84_10480	COG0492	ferredoxin-NADP+ reductase activity
CDO84_10485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO84_10490	COG4862	establishment of competence for transformation
CDO84_10495	COG1408	metallophosphoesterase
CDO84_10505	COG1388	LysM domain
CDO84_10510	COG1266	CAAX protease self-immunity
CDO84_10515	COG0514	ATP-dependent DNA helicase (RecQ)
CDO84_10520	COG4955	Helix-turn-helix domain
CDO84_10525	COG1141	Ferredoxin
CDO84_10530	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CDO84_10535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDO84_10540	COG0710	3-dehydroquinate dehydratase activity
CDO84_10550	COG1595	DNA-templated transcription, initiation
CDO84_10555	COG5002	protein histidine kinase activity
CDO84_10560	COG0745	RESPONSE REGULATOR receiver
CDO84_10565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO84_10570	COG1333	cytochrome c biogenesis protein
CDO84_10575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_10580	COG1187	pseudouridine synthase activity
CDO84_10585	COG0700	Nucleoside recognition
CDO84_10590	COG2715	membrane protein required for spore maturation
CDO84_10595	COG1686	Belongs to the peptidase S11 family
CDO84_10605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CDO84_10610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CDO84_10615	COG1547	Domain of unknown function (DUF309)
CDO84_10620	COG0456	acetyltransferase
CDO84_10625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDO84_10630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO84_10630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDO84_10635	COG0307	riboflavin synthase, alpha
CDO84_10640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO84_10640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDO84_10650	COG0681	Belongs to the peptidase S26 family
CDO84_10660	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
CDO84_10675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDO84_10685	COG4086	secreted protein
CDO84_10690	COG0019	diaminopimelate decarboxylase activity
CDO84_10695	COG0697	spore germination
CDO84_10710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDO84_10730	COG1191	sigma factor activity
CDO84_10735	COG2172	sigma factor antagonist activity
CDO84_10740	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_10745	COG1686	Belongs to the peptidase S11 family
CDO84_10750	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CDO84_10755	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CDO84_10760	COG4974	Belongs to the 'phage' integrase family
CDO84_10770	COG0735	belongs to the Fur family
CDO84_10775	COG1300	Membrane
CDO84_10785	COG0281	malic enzyme
CDO84_10790	COG1757	Na H antiporter
CDO84_10795	COG1027	Aspartate ammonia-lyase
CDO84_10800	COG0252	asparaginase activity
CDO84_10805	COG1396	sequence-specific DNA binding
CDO84_10810	COG1379	DNA repair
CDO84_10815	COG0494	nUDIX hydrolase
CDO84_10825	COG0667	Aldo Keto reductase
CDO84_10835	COG1073	alpha beta
CDO84_10845	COG4918	Iron-sulphur cluster biosynthesis
CDO84_10850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CDO84_10850	COG0456	acetyltransferase
CDO84_10855	COG2329	Antibiotic biosynthesis monooxygenase
CDO84_10860	COG0456	acetyltransferase
CDO84_10870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO84_10880	COG2211	Major facilitator Superfamily
CDO84_10890	COG0346	lactoylglutathione lyase activity
CDO84_10895	COG1072	(Pantothenic acid kinase))
CDO84_10900	COG3048	D-serine ammonia-lyase activity
CDO84_10905	COG0300	oxidoreductase activity
CDO84_10910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_10915	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO84_10920	COG4187	Peptidase family M20/M25/M40
CDO84_10925	COG1902	pentaerythritol trinitrate reductase activity
CDO84_10930	COG0596	Alpha beta hydrolase
CDO84_10940	COG1234	tRNA 3'-trailer cleavage
CDO84_10945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDO84_10950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDO84_10955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CDO84_10965	COG0706	membrane insertase activity
CDO84_10970	COG3361	conserved protein (COG2071)
CDO84_10975	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO84_10980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CDO84_10985	COG0346	lactoylglutathione lyase activity
CDO84_10990	COG1376	ErfK ybiS ycfS ynhG family protein
CDO84_10995	COG4129	membrane
CDO84_11000	COG1126	abc transporter atp-binding protein
CDO84_11005	COG0765	amino acid transport
CDO84_11010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO84_11020	COG1597	lipid kinase activity
CDO84_11025	COG2814	Major facilitator Superfamily
CDO84_11030	COG4978	Transcriptional regulator
CDO84_11030	COG0789	Transcriptional regulator
CDO84_11035	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDO84_11040	COG0022	dehydrogenase e1 component
CDO84_11045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDO84_11050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDO84_11055	COG3426	butyrate kinase activity
CDO84_11060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO84_11065	COG0280	phosphate acetyltransferase
CDO84_11070	COG3290	protein histidine kinase activity
CDO84_11070	COG3829	transcription factor binding
CDO84_11080	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CDO84_11085	COG2079	MmgE PrpD family protein
CDO84_11090	COG0372	Belongs to the citrate synthase family
CDO84_11095	COG1960	acyl-CoA dehydrogenase activity
CDO84_11100	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO84_11105	COG0183	Belongs to the thiolase family
CDO84_11110	COG0584	glycerophosphoryl diester phosphodiesterase
CDO84_11115	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO84_11125	COG1902	pentaerythritol trinitrate reductase activity
CDO84_11135	COG0745	RESPONSE REGULATOR receiver
CDO84_11145	COG0750	zinc metalloprotease
CDO84_11150	COG0497	DNA recombination
CDO84_11155	COG1438	arginine binding
CDO84_11160	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CDO84_11165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDO84_11170	COG0142	geranyltranstransferase activity
CDO84_11175	COG1722	exodeoxyribonuclease VII activity
CDO84_11180	COG1570	exodeoxyribonuclease VII activity
CDO84_11185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDO84_11190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDO84_11195	COG1302	Protein conserved in bacteria
CDO84_11200	COG0439	Biotin carboxylase
CDO84_11205	COG0511	ligase activity, forming carbon-carbon bonds
CDO84_11245	COG3854	ATPases associated with a variety of cellular activities
CDO84_11255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDO84_11260	COG0006	proline dipeptidase activity
CDO84_11265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDO84_11275	COG3872	metal-dependent enzyme
CDO84_11285	COG1752	Esterase of the alpha-beta hydrolase superfamily
CDO84_11290	COG1321	iron dependent repressor
CDO84_11295	COG0095	Lipoate-protein ligase
CDO84_11300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDO84_11305	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO84_11310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDO84_11315	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDO84_11320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDO84_11335	COG1396	sequence-specific DNA binding
CDO84_11345	COG0681	Belongs to the peptidase S26 family
CDO84_11370	COG4940	Competence protein ComGF
CDO84_11380	COG4970	Tfp pilus assembly protein FimT
CDO84_11385	COG4537	Required for transformation and DNA binding
CDO84_11390	COG1459	type II secretion system
CDO84_11395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDO84_11405	COG0517	IMP dehydrogenase activity
CDO84_11410	COG0598	Magnesium transport protein CorA
CDO84_11415	COG1253	flavin adenine dinucleotide binding
CDO84_11420	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_11430	COG1393	Belongs to the ArsC family
CDO84_11440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_11450	COG0011	TIGRFAM Protein of
CDO84_11460	COG2866	Carboxypeptidase
CDO84_11465	COG1368	sulfuric ester hydrolase activity
CDO84_11470	COG1940	carbohydrate kinase activity
CDO84_11480	COG0457	Tetratricopeptide repeat
CDO84_11480	COG0705	Rhomboid family
CDO84_11490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDO84_11495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDO84_11500	COG0438	transferase activity, transferring glycosyl groups
CDO84_11515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDO84_11520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDO84_11525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDO84_11530	COG0581	inorganic phosphate transmembrane transporter activity
CDO84_11535	COG0573	inorganic phosphate transmembrane transporter activity
CDO84_11540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDO84_11550	COG0477	Major facilitator Superfamily
CDO84_11555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CDO84_11560	COG2839	Protein conserved in bacteria
CDO84_11565	COG5521	maltodextrose utilization protein MalA
CDO84_11570	COG1388	LysM domain
CDO84_11575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDO84_11580	COG4709	membrane
CDO84_11585	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CDO84_11590	COG0735	belongs to the Fur family
CDO84_11595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDO84_11605	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CDO84_11610	COG0513	Belongs to the DEAD box helicase family
CDO84_11620	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDO84_11625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CDO84_11630	COG2384	SAM-dependent methyltransferase
CDO84_11635	COG2010	Cytochrome c
CDO84_11645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDO84_11650	COG0358	DNA primase activity
CDO84_11655	COG1671	Belongs to the UPF0178 family
CDO84_11660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CDO84_11665	COG0517	IMP dehydrogenase activity
CDO84_11670	COG0751	glycine-tRNA ligase activity
CDO84_11675	COG0752	glycyl-tRNA synthetase alpha subunit
CDO84_11680	COG1381	Involved in DNA repair and RecF pathway recombination
CDO84_11690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDO84_11695	COG0295	cytidine deaminase activity
CDO84_11700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDO84_11705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDO84_11710	COG1480	7TM receptor with intracellular HD hydrolase
CDO84_11715	COG1702	phosphate starvation-inducible protein PhoH
CDO84_11720	COG0561	phosphatase activity
CDO84_11735	COG4864	UPF0365 protein
CDO84_11740	COG1030	water channel activity
CDO84_11745	COG1610	YqeY-like protein
CDO84_11750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDO84_11755	COG1283	sodium-dependent phosphate transmembrane transporter activity
CDO84_11760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDO84_11765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDO84_11770	COG2264	protein methyltransferase activity
CDO84_11775	COG0484	heat shock protein binding
CDO84_11785	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDO84_11790	COG1420	regulation of RNA biosynthetic process
CDO84_11795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDO84_11800	COG0481	GTPase activity
CDO84_11810	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO84_11815	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CDO84_11820	COG0268	Binds directly to 16S ribosomal RNA
CDO84_11825	COG1466	dna polymerase III delta subunit
CDO84_11835	COG2333	competence protein COMEC
CDO84_11835	COG0658	competence protein
CDO84_11840	COG2131	deaminase
CDO84_11845	COG1555	photosystem II stabilization
CDO84_11845	COG1596	polysaccharide export
CDO84_11850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDO84_11855	COG2226	methyltransferase
CDO84_11860	COG0799	negative regulation of ribosome biogenesis
CDO84_11865	COG1713	HD superfamily hydrolase involved in NAD metabolism
CDO84_11870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDO84_11875	COG1534	Rna-binding protein
CDO84_11880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDO84_11885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CDO84_11890	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CDO84_11900	COG2755	lipolytic protein G-D-S-L family
CDO84_11905	COG0398	Pfam SNARE associated Golgi protein
CDO84_11920	COG3209	COG3209 Rhs family protein
CDO84_11930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CDO84_11945	COG0604	alcohol dehydrogenase
CDO84_11955	COG3403	YqcI/YcgG family
CDO84_11975	COG1215	transferase activity, transferring glycosyl groups
CDO84_11980	COG0463	Glycosyl transferase, family 2
CDO84_11980	COG0457	Tetratricopeptide repeat
CDO84_12000	COG0662	Cupin 2, conserved barrel domain protein
CDO84_12015	COG0457	Tetratricopeptide repeat
CDO84_12025	COG5444	nuclease activity
CDO84_12060	COG5632	N-Acetylmuramoyl-L-alanine amidase
CDO84_12060	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_12060	COG1388	LysM domain
CDO84_12065	COG4824	toxin secretion phage lysis holin
CDO84_12095	COG3778	Protein conserved in bacteria
CDO84_12100	COG3299	homolog of phage Mu protein gp47
CDO84_12105	COG3628	GPW Gp25 family protein
CDO84_12115	COG4193	domain, Protein
CDO84_12120	COG1652	LysM domain
CDO84_12125	COG5280	Phage tail tape measure protein TP901
CDO84_12125	COG3953	SLT domain
CDO84_12190	COG4653	Phage capsid family
CDO84_12195	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CDO84_12205	COG2369	cell adhesion
CDO84_12210	COG5518	Phage portal protein
CDO84_12215	COG1783	phage Terminase large subunit
CDO84_12220	COG5484	DNA packaging
CDO84_12230	COG3677	Transposase
CDO84_12255	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
CDO84_12265	COG1484	DNA-dependent DNA replication
CDO84_12270	COG3935	DnaD domain protein
CDO84_12275	COG3723	Recombinational DNA repair protein, rece pathway
CDO84_12280	COG5377	YqaJ viral recombinase family
CDO84_12310	COG3620	sequence-specific DNA binding
CDO84_12320	COG2856	Zn peptidase
CDO84_12350	COG0457	Tetratricopeptide repeat
CDO84_12365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO84_12375	COG5444	nuclease activity
CDO84_12385	COG2732	(Barnase) inhibitor
CDO84_12400	COG0563	adenylate kinase activity
CDO84_12405	COG2856	Zn peptidase
CDO84_12410	COG1331	Highly conserved protein containing a thioredoxin domain
CDO84_12420	COG0730	response to heat
CDO84_12425	COG0425	Belongs to the sulfur carrier protein TusA family
CDO84_12435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDO84_12435	COG0425	Belongs to the sulfur carrier protein TusA family
CDO84_12445	COG2210	Belongs to the sulfur carrier protein TusA family
CDO84_12450	COG1937	Protein conserved in bacteria
CDO84_12465	COG0662	Cupin 2, conserved barrel domain protein
CDO84_12475	COG0789	Transcriptional regulator
CDO84_12475	COG4978	Transcriptional regulator
CDO84_12480	COG2814	Major facilitator Superfamily
CDO84_12485	COG0456	acetyltransferase
CDO84_12505	COG2068	MobA-Related Protein
CDO84_12510	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDO84_12530	COG2072	flavoprotein involved in K transport
CDO84_12545	COG3299	homolog of phage Mu protein gp47
CDO84_12550	COG1335	isochorismatase
CDO84_12560	COG2318	DinB family
CDO84_12570	COG0583	DNA-binding transcription factor activity
CDO84_12575	COG2070	2-Nitropropane dioxygenase
CDO84_12580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDO84_12590	COG2186	Transcriptional regulator
CDO84_12600	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_12605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDO84_12610	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDO84_12615	COG0477	Major facilitator Superfamily
CDO84_12620	COG1846	Transcriptional regulator
CDO84_12625	COG3443	Belongs to the bacterial solute-binding protein 9 family
CDO84_12635	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_12640	COG5566	PFAM Mor transcription activator
CDO84_12645	COG0596	Alpha beta hydrolase
CDO84_12650	COG4991	sh3 domain protein
CDO84_12655	COG4991	sh3 domain protein
CDO84_12660	COG0346	lactoylglutathione lyase activity
CDO84_12670	COG5577	PFAM Coat F domain
CDO84_12675	COG1063	alcohol dehydrogenase
CDO84_12685	COG5577	PFAM Coat F domain
CDO84_12690	COG1621	beta-fructofuranosidase activity
CDO84_12695	COG3716	PTS system mannose fructose sorbose family IID component
CDO84_12700	COG3715	PTS system
CDO84_12705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_12710	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_12715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CDO84_12715	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CDO84_12720	COG1113	amino acid transport
CDO84_12725	COG1280	lysine exporter protein (LysE YggA)
CDO84_12730	COG1378	Sugar-specific transcriptional regulator TrmB
CDO84_12735	COG1595	DNA-templated transcription, initiation
CDO84_12745	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CDO84_12745	COG2755	lipolytic protein G-D-S-L family
CDO84_12755	COG2124	cytochrome p450
CDO84_12755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDO84_12760	COG1309	transcriptional regulator
CDO84_12765	COG2226	methyltransferase
CDO84_12775	COG2116	formate transmembrane transporter activity
CDO84_12780	COG5609	conserved protein (DUF2294)
CDO84_12785	COG3383	formate dehydrogenase (NAD+) activity
CDO84_12790	COG2427	Protein of unknown function (DUF1641)
CDO84_12800	COG0626	cystathionine gamma-synthase activity
CDO84_12805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDO84_12810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CDO84_12815	COG2226	methyltransferase
CDO84_12830	COG0768	penicillin binding
CDO84_12835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CDO84_12840	COG0572	uridine kinase
CDO84_12860	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CDO84_12865	COG3906	Belongs to the UPF0473 family
CDO84_12870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDO84_12875	COG4472	Bacterial protein of unknown function (DUF965)
CDO84_12880	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDO84_12885	COG0628	permease
CDO84_12900	COG3881	PFAM PRC-barrel domain
CDO84_12905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CDO84_12910	COG0457	Tetratricopeptide repeat
CDO84_12915	COG0482	sulfurtransferase activity
CDO84_12920	COG1104	cysteine desulfurase activity
CDO84_12925	COG1959	2 iron, 2 sulfur cluster binding
CDO84_12930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CDO84_12935	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CDO84_12945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDO84_12950	COG0124	histidyl-tRNA synthetase
CDO84_12960	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO84_12960	COG3103	Sh3 type 3 domain protein
CDO84_12960	COG4991	sh3 domain protein
CDO84_12965	COG1490	D-aminoacyl-tRNA deacylase activity
CDO84_12970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDO84_12975	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO84_12980	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDO84_12980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDO84_12985	COG5416	Lipopolysaccharide assembly protein A domain
CDO84_12990	COG0490	domain, Protein
CDO84_12995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDO84_12995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDO84_13005	COG2244	polysaccharide biosynthetic process
CDO84_13010	COG2323	membrane
CDO84_13020	COG1862	Preprotein translocase
CDO84_13025	COG0343	queuine tRNA-ribosyltransferase activity
CDO84_13030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDO84_13040	COG2255	four-way junction helicase activity
CDO84_13045	COG0632	four-way junction helicase activity
CDO84_13055	COG2814	Major facilitator Superfamily
CDO84_13060	COG0673	inositol 2-dehydrogenase activity
CDO84_13065	COG2112	serine threonine protein kinase
CDO84_13075	COG1115	amino acid carrier protein
CDO84_13080	COG0217	transcriptional regulatory protein
CDO84_13090	COG1388	LysM domain
CDO84_13095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDO84_13100	COG0157	Belongs to the NadC ModD family
CDO84_13105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CDO84_13110	COG1104	cysteine desulfurase activity
CDO84_13115	COG1827	regulation of RNA biosynthetic process
CDO84_13120	COG0077	Prephenate dehydratase
CDO84_13125	COG4492	Belongs to the UPF0735 family
CDO84_13130	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDO84_13135	COG3290	protein histidine kinase activity
CDO84_13140	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDO84_13145	COG2868	ribosomal protein
CDO84_13150	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDO84_13155	COG1994	Peptidase M50
CDO84_13160	COG0739	heme binding
CDO84_13165	COG2894	cell division
CDO84_13170	COG0850	regulation of cytokinetic process
CDO84_13175	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CDO84_13180	COG1792	Involved in formation and maintenance of cell shape
CDO84_13185	COG1077	Cell shape determining protein MreB Mrl
CDO84_13190	COG2003	Belongs to the UPF0758 family
CDO84_13195	COG0424	maF-like protein
CDO84_13205	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CDO84_13210	COG0285	dihydrofolate synthase activity
CDO84_13215	COG0525	valine-tRNA ligase activity
CDO84_13225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO84_13230	COG1388	LysM domain
CDO84_13235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDO84_13240	COG0113	porphobilinogen synthase activity
CDO84_13245	COG1587	Uroporphyrinogen-III synthase
CDO84_13250	COG0181	hydroxymethylbilane synthase activity
CDO84_13255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDO84_13260	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CDO84_13270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CDO84_13275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CDO84_13280	COG0470	DNA polymerase III
CDO84_13280	COG1067	ATP-dependent peptidase activity
CDO84_13285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDO84_13290	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDO84_13295	COG0457	Tetratricopeptide repeat
CDO84_13295	COG1477	protein flavinylation
CDO84_13300	COG0066	3-isopropylmalate dehydratase activity
CDO84_13305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDO84_13310	COG0473	3-isopropylmalate dehydrogenase activity
CDO84_13315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDO84_13320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDO84_13325	COG0440	acetolactate synthase activity
CDO84_13330	COG0028	Belongs to the TPP enzyme family
CDO84_13345	COG0454	-acetyltransferase
CDO84_13350	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
CDO84_13375	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CDO84_13390	COG0622	Phosphoesterase
CDO84_13395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDO84_13400	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDO84_13405	COG5401	PFAM Sporulation and spore germination
CDO84_13410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDO84_13415	COG1846	Transcriptional regulator
CDO84_13420	COG2197	response regulator
CDO84_13425	COG0824	Thioesterase
CDO84_13430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDO84_13435	COG1053	succinate dehydrogenase
CDO84_13440	COG2009	succinate dehydrogenase
CDO84_13445	COG1719	4-vinyl reductase, 4VR
CDO84_13450	COG0527	aspartate kinase activity
CDO84_13460	COG0322	excinuclease ABC activity
CDO84_13465	COG3118	belongs to the thioredoxin family
CDO84_13475	COG3534	alpha-L-arabinofuranosidase
CDO84_13480	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CDO84_13485	COG2086	electron transfer activity
CDO84_13490	COG1024	Enoyl-CoA hydratase
CDO84_13495	COG1309	transcriptional regulator
CDO84_13500	COG0318	PFAM AMP-dependent synthetase and ligase
CDO84_13505	COG3766	membrane
CDO84_13510	COG1193	negative regulation of DNA recombination
CDO84_13515	COG1796	DNA polymerase
CDO84_13515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDO84_13520	COG1286	toxin biosynthetic process
CDO84_13525	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CDO84_13530	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDO84_13535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO84_13535	COG0072	phenylalanine-tRNA ligase activity
CDO84_13540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDO84_13550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO84_13560	COG3835	regulator
CDO84_13565	COG0277	FAD linked oxidase domain protein
CDO84_13570	COG0247	lactate metabolic process
CDO84_13575	COG0346	lactoylglutathione lyase activity
CDO84_13585	COG1966	Carbon starvation protein
CDO84_13600	COG1695	Transcriptional regulator
CDO84_13605	COG3534	alpha-L-arabinofuranosidase
CDO84_13610	COG0395	ABC-type sugar transport system, permease component
CDO84_13615	COG1175	transmembrane transport
CDO84_13620	COG1653	transport
CDO84_13625	COG0371	Dehydrogenase
CDO84_13630	COG0647	UMP catabolic process
CDO84_13635	COG0235	Class ii aldolase
CDO84_13640	COG1069	ribulokinase activity
CDO84_13645	COG2160	L-arabinose isomerase activity
CDO84_13650	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO84_13655	COG1363	Peptidase, m42
CDO84_13665	COG3326	Membrane
CDO84_13670	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDO84_13675	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDO84_13680	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDO84_13690	COG1346	cytolysis
CDO84_13695	COG1380	Effector of murein hydrolase LrgA
CDO84_13700	COG3279	Response regulator of the LytR AlgR family
CDO84_13705	COG3275	phosphorelay sensor kinase activity
CDO84_13715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDO84_13725	COG0398	Pfam SNARE associated Golgi protein
CDO84_13730	COG1484	DNA-dependent DNA replication
CDO84_13735	COG3611	Membrane attachment protein
CDO84_13740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDO84_13745	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CDO84_13750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDO84_13755	COG1733	regulation of RNA biosynthetic process
CDO84_13760	COG2814	Major facilitator Superfamily
CDO84_13765	COG0656	L-ascorbic acid biosynthetic process
CDO84_13770	COG0237	dephospho-CoA kinase activity
CDO84_13775	COG1971	Probably functions as a manganese efflux pump
CDO84_13780	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDO84_13785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO84_13785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDO84_13790	COG5002	protein histidine kinase activity
CDO84_13795	COG0745	RESPONSE REGULATOR receiver
CDO84_13800	COG0039	L-malate dehydrogenase activity
CDO84_13805	COG0538	isocitrate dehydrogenase activity
CDO84_13810	COG0372	Belongs to the citrate synthase family
CDO84_13815	COG2707	UPF0756 membrane protein
CDO84_13820	COG0628	permease
CDO84_13825	COG3030	protein affecting phage T7 exclusion by the F plasmid
CDO84_13830	COG0469	pyruvate kinase activity
CDO84_13835	COG0205	6-phosphofructokinase activity
CDO84_13840	COG0825	malonyl-CoA metabolic process
CDO84_13845	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDO84_13850	COG0281	malic enzyme
CDO84_13855	COG0587	DNA-directed DNA polymerase activity
CDO84_13875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDO84_13885	COG4109	DRTGG domain
CDO84_13890	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CDO84_13895	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_13905	COG0165	Argininosuccinate lyase
CDO84_13910	COG0137	argininosuccinate synthase activity
CDO84_13915	COG0521	Mo-molybdopterin cofactor biosynthetic process
CDO84_13920	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDO84_13930	COG0827	DNA restriction-modification system
CDO84_13935	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CDO84_13940	COG3874	Sporulation protein YtfJ
CDO84_13950	COG1714	RDD family
CDO84_13955	COG0616	signal peptide processing
CDO84_13960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDO84_13965	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CDO84_13970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO84_13980	COG0301	tRNA thio-modification
CDO84_13985	COG1104	cysteine desulfurase activity
CDO84_13990	COG1114	Component of the transport system for branched-chain amino acids
CDO84_13995	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CDO84_14000	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CDO84_14005	COG1309	transcriptional regulator
CDO84_14010	COG1956	GAF domain-containing protein
CDO84_14015	COG2199	diguanylate cyclase activity
CDO84_14015	COG2203	Gaf domain
CDO84_14025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDO84_14030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDO84_14040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDO84_14045	COG0454	-acetyltransferase
CDO84_14050	COG0517	IMP dehydrogenase activity
CDO84_14055	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDO84_14060	COG1360	Flagellar Motor Protein
CDO84_14065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CDO84_14070	COG1609	Transcriptional regulator
CDO84_14075	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDO84_14075	COG1605	Chorismate mutase
CDO84_14080	COG3118	belongs to the thioredoxin family
CDO84_14085	COG4980	gas vesicle protein
CDO84_14090	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CDO84_14095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDO84_14100	COG1674	ftsk spoiiie
CDO84_14105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO84_14110	COG4848	Belongs to the UPF0354 family
CDO84_14115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_14125	COG1363	Peptidase, m42
CDO84_14130	COG5584	Small secreted protein
CDO84_14135	COG0281	malic enzyme
CDO84_14140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_14145	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDO84_14155	COG0510	thiamine kinase activity
CDO84_14160	COG1523	belongs to the glycosyl hydrolase 13 family
CDO84_14165	COG1597	lipid kinase activity
CDO84_14175	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CDO84_14180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDO84_14185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO84_14190	COG2252	PERMEase
CDO84_14195	COG4473	ABC transporter
CDO84_14200	COG1131	(ABC) transporter
CDO84_14205	COG1349	DNA-binding transcription factor activity
CDO84_14210	COG1187	pseudouridine synthase activity
CDO84_14215	COG2244	polysaccharide biosynthetic process
CDO84_14220	COG2081	HI0933 family
CDO84_14225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CDO84_14235	COG5578	integral membrane protein
CDO84_14240	COG0673	inositol 2-dehydrogenase activity
CDO84_14245	COG1653	transport
CDO84_14250	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CDO84_14255	COG4209	transmembrane transport
CDO84_14260	COG2207	Transcriptional regulator
CDO84_14265	COG1653	transport
CDO84_14270	COG0395	ABC-type sugar transport system, permease component
CDO84_14275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO84_14280	COG2124	cytochrome p450
CDO84_14285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDO84_14295	COG0156	8-amino-7-oxononanoate synthase activity
CDO84_14300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDO84_14315	COG1073	alpha beta
CDO84_14340	COG1486	melibiose metabolic process
CDO84_14345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDO84_14350	COG0495	leucyl-tRNA aminoacylation
CDO84_14360	COG1366	Belongs to the anti-sigma-factor antagonist family
CDO84_14360	COG2202	Pas domain
CDO84_14365	COG2814	Major facilitator Superfamily
CDO84_14370	COG2433	Pfam Transposase IS66
CDO84_14375	COG0577	efflux transmembrane transporter activity
CDO84_14380	COG1136	(ABC) transporter
CDO84_14385	COG2205	protein histidine kinase activity
CDO84_14390	COG0745	RESPONSE REGULATOR receiver
CDO84_14395	COG0577	efflux transmembrane transporter activity
CDO84_14400	COG1136	(ABC) transporter
CDO84_14415	COG1131	(ABC) transporter
CDO84_14420	COG1725	Transcriptional regulator
CDO84_14430	COG1242	4 iron, 4 sulfur cluster binding
CDO84_14435	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CDO84_14445	COG2267	carboxylic ester hydrolase activity
CDO84_14450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDO84_14455	COG1113	amino acid transport
CDO84_14460	COG0367	asparagine synthase
CDO84_14465	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDO84_14470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CDO84_14480	COG1506	peptidase
CDO84_14485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDO84_14490	COG1116	anion transmembrane transporter activity
CDO84_14495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDO84_14500	COG0494	nUDIX hydrolase
CDO84_14505	COG4824	toxin secretion phage lysis holin
CDO84_14515	COG0783	Belongs to the Dps family
CDO84_14530	COG1854	S-ribosylhomocysteine lyase activity
CDO84_14535	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDO84_14540	COG0288	reversible hydration of carbon dioxide
CDO84_14545	COG0254	rRNA binding
CDO84_14550	COG1271	oxidase subunit
CDO84_14555	COG1294	oxidase, subunit
CDO84_14565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO84_14570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDO84_14570	COG1321	iron dependent repressor
CDO84_14575	COG1121	(ABC) transporter
CDO84_14580	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDO84_14585	COG4948	Mandelate Racemase Muconate Lactonizing
CDO84_14590	COG0318	PFAM AMP-dependent synthetase and ligase
CDO84_14595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CDO84_14600	COG0596	Alpha beta hydrolase
CDO84_14605	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDO84_14610	COG1169	isochorismate synthase
CDO84_14620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CDO84_14625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO84_14630	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDO84_14635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDO84_14640	COG0438	transferase activity, transferring glycosyl groups
CDO84_14650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO84_14655	COG0438	transferase activity, transferring glycosyl groups
CDO84_14660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO84_14665	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CDO84_14670	COG0058	SHG alpha-glucan phosphorylase activity
CDO84_14675	COG0297	glycogen (starch) synthase activity
CDO84_14680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDO84_14685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDO84_14690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDO84_14815	COG3859	Proton-coupled thiamine transporter YuaJ
CDO84_14820	COG1247	-acetyltransferase
CDO84_14825	COG2268	Band 7 protein
CDO84_14830	COG1585	Membrane protein implicated in regulation of membrane protease activity
CDO84_14835	COG2318	DinB family
CDO84_14845	COG1454	alcohol dehydrogenase
CDO84_14855	COG1510	regulation of RNA biosynthetic process
CDO84_14865	COG0569	domain protein
CDO84_14870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDO84_14875	COG4682	membrane
CDO84_14880	COG1705	Flagellar rod assembly protein muramidase FlgJ
CDO84_14885	COG0477	Major facilitator Superfamily
CDO84_14895	COG5553	Cysteine dioxygenase type I
CDO84_14905	COG1968	undecaprenyl-diphosphatase activity
CDO84_14910	COG0628	permease
CDO84_14915	COG0673	inositol 2-dehydrogenase activity
CDO84_14920	COG4806	L-rhamnose isomerase
CDO84_14925	COG3254	rhamnose metabolic process
CDO84_14930	COG1070	Carbohydrate kinase
CDO84_14935	COG1349	DNA-binding transcription factor activity
CDO84_14940	COG3347	Dehydrogenase
CDO84_14940	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_14950	COG0840	transmembrane signaling receptor activity
CDO84_14955	COG0840	transmembrane signaling receptor activity
CDO84_14960	COG0840	transmembrane signaling receptor activity
CDO84_14965	COG0840	transmembrane signaling receptor activity
CDO84_14980	COG0432	Pfam Uncharacterised protein family UPF0047
CDO84_14985	COG0366	Alpha amylase catalytic
CDO84_14990	COG1253	flavin adenine dinucleotide binding
CDO84_14995	COG2738	Putative neutral zinc metallopeptidase
CDO84_15010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CDO84_15025	COG0166	Belongs to the GPI family
CDO84_15030	COG1979	alcohol dehydrogenase
CDO84_15035	COG1979	alcohol dehydrogenase
CDO84_15040	COG2155	Conserved Protein
CDO84_15045	COG1098	S1 RNA binding domain
CDO84_15050	COG0436	Aminotransferase
CDO84_15055	COG1522	sequence-specific DNA binding
CDO84_15060	COG2267	carboxylic ester hydrolase activity
CDO84_15070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CDO84_15075	COG2205	protein histidine kinase activity
CDO84_15085	COG5018	Exonuclease
CDO84_15095	COG2814	Major facilitator Superfamily
CDO84_15100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO84_15105	COG3011	Protein conserved in bacteria
CDO84_15115	COG3290	protein histidine kinase activity
CDO84_15120	COG4565	transcriptional regulatory protein
CDO84_15145	COG3493	citrate carrier protein
CDO84_15155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDO84_15155	COG2111	Na H antiporter
CDO84_15160	COG2111	Na H antiporter
CDO84_15165	COG1006	Multisubunit Na H antiporter MnhC subunit
CDO84_15170	COG0651	ATP synthesis coupled electron transport
CDO84_15175	COG1863	multisubunit Na H antiporter MnhE subunit
CDO84_15180	COG2212	antiporter activity
CDO84_15185	COG1320	monovalent cation:proton antiporter activity
CDO84_15190	COG2050	protein possibly involved in aromatic compounds catabolism
CDO84_15195	COG2197	response regulator
CDO84_15200	COG4585	Histidine kinase
CDO84_15210	COG0142	geranyltranstransferase activity
CDO84_15225	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CDO84_15230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CDO84_15235	COG1335	isochorismatase
CDO84_15240	COG5506	Protein of unknown function (DUF1694)
CDO84_15255	COG0628	permease
CDO84_15270	COG1418	mRNA catabolic process
CDO84_15275	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_15285	COG1511	domain protein
CDO84_15290	COG1674	ftsk spoiiie
CDO84_15290	COG0433	COG0433 Predicted ATPase
CDO84_15295	COG4499	WXG100 protein secretion system (Wss), protein YukC
CDO84_15300	COG5417	Belongs to the EsaB family
CDO84_15305	COG4842	Belongs to the WXG100 family
CDO84_15310	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CDO84_15310	COG2508	Transcriptional regulator
CDO84_15315	COG0686	Belongs to the AlaDH PNT family
CDO84_15320	COG5634	Uncharacterized conserved protein (DUF2278)
CDO84_15325	COG3251	PFAM MbtH domain protein
CDO84_15330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_15335	COG1535	isochorismatase
CDO84_15335	COG3433	isochorismatase activity
CDO84_15340	COG1021	2,3-dihydroxybenzoate-AMP ligase
CDO84_15345	COG1169	isochorismate synthase
CDO84_15350	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_15355	COG2819	hydrolase of the alpha beta superfamily
CDO84_15360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CDO84_15365	COG1268	BioY protein
CDO84_15370	COG2056	Na+-H+ antiporter family
CDO84_15375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDO84_15380	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CDO84_15385	COG3584	3D domain protein
CDO84_15400	COG1252	NADH dehydrogenase
CDO84_15405	COG0492	ferredoxin-NADP+ reductase activity
CDO84_15415	COG0516	GMP reductase activity
CDO84_15420	COG2808	Putative FMN-binding domain
CDO84_15425	COG0456	acetyltransferase
CDO84_15430	COG0316	Belongs to the HesB IscA family
CDO84_15435	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDO84_15440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDO84_15445	COG4844	belongs to the
CDO84_15450	COG1252	NADH dehydrogenase
CDO84_15455	COG4837	Protein of unknown function (DUF1462)
CDO84_15460	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDO84_15465	COG4946	Tricorn protease homolog
CDO84_15465	COG1506	peptidase
CDO84_15465	COG0823	Involved in the tonB-independent uptake of proteins
CDO84_15470	COG0083	homoserine kinase activity
CDO84_15475	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDO84_15480	COG0460	homoserine dehydrogenase
CDO84_15485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CDO84_15490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CDO84_15495	COG0647	UMP catabolic process
CDO84_15500	COG2445	Protein of unknown function DUF86
CDO84_15505	COG4470	Protein conserved in bacteria
CDO84_15515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDO84_15520	COG0739	heme binding
CDO84_15530	COG3377	Domain of unknown function (DUF1805)
CDO84_15535	COG0737	Belongs to the 5'-nucleotidase family
CDO84_15540	COG0730	response to heat
CDO84_15545	COG1801	Protein of unknown function DUF72
CDO84_15555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDO84_15560	COG2508	Transcriptional regulator
CDO84_15565	COG2233	PERMEase
CDO84_15570	COG2233	PERMEase
CDO84_15575	COG3648	Uricase
CDO84_15575	COG3195	allantoin biosynthetic process
CDO84_15580	COG2351	hydroxyisourate hydrolase activity
CDO84_15585	COG1595	DNA-templated transcription, initiation
CDO84_15655	COG2080	2 iron, 2 sulfur cluster binding
CDO84_15660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CDO84_15665	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CDO84_15670	COG2068	MobA-Related Protein
CDO84_15675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CDO84_15680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CDO84_15685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CDO84_15695	COG2356	endonuclease I
CDO84_15700	COG3842	ATPase activity
CDO84_15705	COG2188	Transcriptional regulator
CDO84_15710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO84_15715	COG0395	ABC-type sugar transport system, permease component
CDO84_15720	COG1175	transmembrane transport
CDO84_15725	COG1653	transport
CDO84_15730	COG2222	sugar isomerase
CDO84_15735	COG0322	excinuclease ABC activity
CDO84_15740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDO84_15755	COG0719	Fe-S assembly protein
CDO84_15760	COG0822	iron-sulfur transferase activity
CDO84_15765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDO84_15770	COG0719	Fe-S assembly protein
CDO84_15775	COG0396	ATPase activity
CDO84_15790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CDO84_15795	COG1464	Belongs to the NlpA lipoprotein family
CDO84_15800	COG2011	ABC-type metal ion transport system permease component
CDO84_15805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDO84_15815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDO84_15820	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CDO84_15830	COG0509	glycine decarboxylation via glycine cleavage system
CDO84_15835	COG1393	Belongs to the ArsC family
CDO84_15840	COG1960	acyl-CoA dehydrogenase activity
CDO84_15845	COG0183	Belongs to the thiolase family
CDO84_15850	COG1024	Enoyl-CoA hydratase
CDO84_15850	COG1250	3-hydroxyacyl-CoA dehydrogenase
CDO84_15860	COG0506	proline dehydrogenase activity
CDO84_15870	COG5577	PFAM Coat F domain
CDO84_15875	COG1846	Transcriptional regulator
CDO84_15880	COG0477	Major facilitator Superfamily
CDO84_15885	COG1942	4-Oxalocrotonate Tautomerase
CDO84_15890	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_15895	COG0583	DNA-binding transcription factor activity
CDO84_15905	COG1120	ATPase activity
CDO84_15925	COG1131	(ABC) transporter
CDO84_15970	COG0783	Belongs to the Dps family
CDO84_15975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO84_15980	COG0745	RESPONSE REGULATOR receiver
CDO84_15985	COG2770	Histidine kinase
CDO84_15985	COG2205	protein histidine kinase activity
CDO84_15995	COG1309	transcriptional regulator
CDO84_16000	COG0114	fumarate hydratase activity
CDO84_16010	COG0697	spore germination
CDO84_16015	COG0814	amino acid
CDO84_16025	COG2197	response regulator
CDO84_16030	COG4585	Histidine kinase
CDO84_16035	COG4758	membrane
CDO84_16040	COG3595	metallopeptidase activity
CDO84_16045	COG1842	Phage shock protein A
CDO84_16050	COG4758	membrane
CDO84_16055	COG2814	Major facilitator Superfamily
CDO84_16060	COG2096	Adenosyltransferase
CDO84_16065	COG1120	ATPase activity
CDO84_16070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_16075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDO84_16080	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_16085	COG3386	PFAM SMP-30 Gluconolaconase
CDO84_16090	COG2205	protein histidine kinase activity
CDO84_16095	COG0745	RESPONSE REGULATOR receiver
CDO84_16105	COG1191	sigma factor activity
CDO84_16115	COG2140	Oxalate decarboxylase
CDO84_16125	COG0577	efflux transmembrane transporter activity
CDO84_16130	COG1136	(ABC) transporter
CDO84_16135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDO84_16140	COG1120	ATPase activity
CDO84_16145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_16150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CDO84_16155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDO84_16165	COG0531	amino acid
CDO84_16180	COG1988	membrane-bound metal-dependent
CDO84_16185	COG1368	sulfuric ester hydrolase activity
CDO84_16190	COG1910	domain protein
CDO84_16195	COG0725	ABC transporter, periplasmic molybdate-binding protein
CDO84_16200	COG4149	molybdate abc transporter
CDO84_16205	COG0656	L-ascorbic acid biosynthetic process
CDO84_16215	COG0025	NhaP-type Na H and K H
CDO84_16220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDO84_16225	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDO84_16230	COG3973	AAA domain
CDO84_16235	COG2860	membrane
CDO84_16240	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CDO84_16245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CDO84_16250	COG2217	Heavy metal translocating P-type atpase
CDO84_16255	COG2217	Heavy metal translocating P-type atpase
CDO84_16260	COG2608	mercury ion transmembrane transporter activity
CDO84_16265	COG1937	Protein conserved in bacteria
CDO84_16270	COG0673	inositol 2-dehydrogenase activity
CDO84_16275	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CDO84_16280	COG1289	transmembrane transporter activity
CDO84_16290	COG2076	Multidrug Resistance protein
CDO84_16295	COG1309	transcriptional regulator
CDO84_16300	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_16310	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDO84_16315	COG0557	exoribonuclease II activity
CDO84_16320	COG1647	Serine aminopeptidase, S33
CDO84_16325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDO84_16330	COG0596	Alpha beta hydrolase
CDO84_16335	COG1476	TRANSCRIPTIONal
CDO84_16340	COG1396	sequence-specific DNA binding
CDO84_16345	COG1396	sequence-specific DNA binding
CDO84_16350	COG1733	regulation of RNA biosynthetic process
CDO84_16355	COG0840	transmembrane signaling receptor activity
CDO84_16360	COG1174	glycine betaine transport
CDO84_16365	COG1732	Glycine betaine
CDO84_16370	COG1174	glycine betaine transport
CDO84_16375	COG0517	IMP dehydrogenase activity
CDO84_16375	COG1125	glycine betaine transport
CDO84_16380	COG1510	regulation of RNA biosynthetic process
CDO84_16385	COG1174	glycine betaine transport
CDO84_16390	COG1732	Glycine betaine
CDO84_16395	COG1174	glycine betaine transport
CDO84_16400	COG1125	glycine betaine transport
CDO84_16400	COG0517	IMP dehydrogenase activity
CDO84_16405	COG1510	regulation of RNA biosynthetic process
CDO84_16410	COG2095	MarC family integral membrane protein
CDO84_16420	COG3064	Membrane
CDO84_16425	COG4640	response to antibiotic
CDO84_16430	COG0456	acetyltransferase
CDO84_16445	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDO84_16450	COG0149	triose-phosphate isomerase activity
CDO84_16455	COG0126	phosphoglycerate kinase activity
CDO84_16460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDO84_16465	COG2390	Transcriptional regulator
CDO84_16470	COG2814	Major facilitator Superfamily
CDO84_16475	COG1609	Transcriptional regulator
CDO84_16480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO84_16490	COG0583	DNA-binding transcription factor activity
CDO84_16495	COG0697	spore germination
CDO84_16500	COG1113	amino acid transport
CDO84_16505	COG3858	chitin binding
CDO84_16510	COG1556	Lactate utilization protein
CDO84_16515	COG1139	Iron-sulfur cluster binding protein
CDO84_16520	COG0247	lactate metabolic process
CDO84_16525	COG2197	response regulator
CDO84_16530	COG4585	Histidine kinase
CDO84_16535	COG0842	Transport permease protein
CDO84_16540	COG1131	(ABC) transporter
CDO84_16545	COG0596	Alpha beta hydrolase
CDO84_16550	COG2208	phosphoserine phosphatase activity
CDO84_16555	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CDO84_16560	COG1874	Beta-galactosidase
CDO84_16565	COG3833	ABC-type maltose transport systems, permease component
CDO84_16570	COG1175	transmembrane transport
CDO84_16575	COG2182	Extracellular solute-binding protein
CDO84_16580	COG1609	Transcriptional regulator
CDO84_16585	COG2186	Transcriptional regulator
CDO84_16590	COG1620	l-lactate permease
CDO84_16595	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CDO84_16605	COG5039	Polysaccharide pyruvyl transferase
CDO84_16610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDO84_16615	COG0110	maltose O-acetyltransferase activity
CDO84_16620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDO84_16625	COG2244	polysaccharide biosynthetic process
CDO84_16630	COG1216	Glycosyl transferase, family 2
CDO84_16635	COG5039	Polysaccharide pyruvyl transferase
CDO84_16640	COG1216	Glycosyl transferase, family 2
CDO84_16650	COG0438	transferase activity, transferring glycosyl groups
CDO84_16655	COG1215	transferase activity, transferring glycosyl groups
CDO84_16660	COG0438	transferase activity, transferring glycosyl groups
CDO84_16665	COG1086	Polysaccharide biosynthesis protein
CDO84_16670	COG0489	protein tyrosine kinase activity
CDO84_16675	COG3944	biosynthesis protein
CDO84_16680	COG1396	sequence-specific DNA binding
CDO84_16685	COG2272	Belongs to the type-B carboxylesterase lipase family
CDO84_16695	COG3479	Phenolic acid decarboxylase
CDO84_16710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CDO84_16715	COG1621	beta-fructofuranosidase activity
CDO84_16720	COG1621	beta-fructofuranosidase activity
CDO84_16725	COG0531	amino acid
CDO84_16730	COG1309	transcriptional regulator
CDO84_16735	COG2076	Multidrug Resistance protein
CDO84_16740	COG2076	Multidrug Resistance protein
CDO84_16755	COG0740	serine-type endopeptidase activity
CDO84_16760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDO84_16765	COG0366	Alpha amylase catalytic
CDO84_16770	COG1554	hydrolase, family 65, central catalytic
CDO84_16775	COG5521	maltodextrose utilization protein MalA
CDO84_16780	COG3833	ABC-type maltose transport systems, permease component
CDO84_16785	COG1175	transmembrane transport
CDO84_16790	COG2182	Extracellular solute-binding protein
CDO84_16800	COG1609	Transcriptional regulator
CDO84_16805	COG1611	Belongs to the LOG family
CDO84_16810	COG1694	Mazg nucleotide pyrophosphohydrolase
CDO84_16815	COG0659	secondary active sulfate transmembrane transporter activity
CDO84_16820	COG0288	reversible hydration of carbon dioxide
CDO84_16825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDO84_16830	COG0577	efflux transmembrane transporter activity
CDO84_16835	COG1136	(ABC) transporter
CDO84_16840	COG5002	protein histidine kinase activity
CDO84_16845	COG0745	RESPONSE REGULATOR receiver
CDO84_16860	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CDO84_16865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_16870	COG1481	regulation of sporulation
CDO84_16875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CDO84_16880	COG1660	Displays ATPase and GTPase activities
CDO84_16885	COG1051	belongs to the nudix hydrolase family
CDO84_16890	COG0492	ferredoxin-NADP+ reductase activity
CDO84_16895	COG0791	NLP P60 protein
CDO84_16895	COG3883	PFAM NLP P60 protein
CDO84_16900	COG0457	Tetratricopeptide repeat
CDO84_16905	COG1132	(ABC) transporter
CDO84_16945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDO84_16945	COG0140	phosphoribosyl-ATP diphosphatase activity
CDO84_16950	COG0107	imidazoleglycerol-phosphate synthase activity
CDO84_16955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDO84_16960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDO84_16965	COG0131	Imidazoleglycerol-phosphate dehydratase
CDO84_16970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDO84_16975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDO84_16980	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDO84_16985	COG4990	cell redox homeostasis
CDO84_16990	COG5297	Belongs to the glycosyl hydrolase family 6
CDO84_16995	COG0110	maltose O-acetyltransferase activity
CDO84_17000	COG0546	phosphoglycolate phosphatase activity
CDO84_17005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CDO84_17010	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDO84_17015	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CDO84_17020	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDO84_17025	COG0363	glucosamine-6-phosphate deaminase activity
CDO84_17035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDO84_17040	COG1950	PFAM Membrane protein of
CDO84_17045	COG1983	PspC domain protein
CDO84_17050	COG3595	metallopeptidase activity
CDO84_17065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO84_17070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDO84_17075	COG0556	nucleotide-excision repair
CDO84_17080	COG4897	Protein conserved in bacteria
CDO84_17085	COG3848	Pyruvate phosphate dikinase
CDO84_17085	COG0574	Belongs to the PEP-utilizing enzyme family
CDO84_17090	COG1309	transcriptional regulator
CDO84_17095	COG2814	Major facilitator Superfamily
CDO84_17100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO84_17110	COG0793	Belongs to the peptidase S41A family
CDO84_17110	COG3409	Peptidoglycan-binding domain 1 protein
CDO84_17115	COG2177	Part of the ABC transporter FtsEX involved in
CDO84_17120	COG2884	Cell division ATP-binding protein ftsE
CDO84_17125	COG2010	Cytochrome c
CDO84_17130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDO84_17140	COG0653	protein targeting
CDO84_17145	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDO84_17160	COG1516	flagellar protein fliS
CDO84_17165	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CDO84_17170	COG1334	flagellar protein FlaG
CDO84_17175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO84_17180	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CDO84_17185	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CDO84_17195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CDO84_17200	COG4786	Flagellar basal body rod
CDO84_17200	COG1256	bacterial-type flagellum assembly
CDO84_17205	COG3418	PFAM FlgN family protein
CDO84_17210	COG2747	anti-sigma28 factor FlgM
CDO84_17220	COG1040	competence protein
CDO84_17230	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CDO84_17235	COG1307	EDD domain protein, DegV family
CDO84_17240	COG2197	response regulator
CDO84_17245	COG4585	Histidine kinase
CDO84_17250	COG1739	Uncharacterized protein family UPF0029
CDO84_17255	COG1316	TRANSCRIPTIONal
CDO84_17260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDO84_17265	COG0438	transferase activity, transferring glycosyl groups
CDO84_17270	COG1215	transferase activity, transferring glycosyl groups
CDO84_17275	COG3206	protein involved in exopolysaccharide biosynthesis
CDO84_17280	COG3307	-O-antigen
CDO84_17285	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDO84_17290	COG0297	glycogen (starch) synthase activity
CDO84_17290	COG0438	transferase activity, transferring glycosyl groups
CDO84_17295	COG2244	polysaccharide biosynthetic process
CDO84_17305	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO84_17305	COG2247	cell wall binding repeat
CDO84_17310	COG2385	sporulation resulting in formation of a cellular spore
CDO84_17310	COG2247	cell wall binding repeat
CDO84_17320	COG1316	TRANSCRIPTIONal
CDO84_17325	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDO84_17330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CDO84_17340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDO84_17340	COG1215	transferase activity, transferring glycosyl groups
CDO84_17345	COG0463	Glycosyl transferase, family 2
CDO84_17365	COG1134	teichoic acid transport
CDO84_17370	COG1682	transport, permease protein
CDO84_17375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDO84_17380	COG0438	transferase activity, transferring glycosyl groups
CDO84_17385	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDO84_17390	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CDO84_17395	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDO84_17405	COG4193	domain, Protein
CDO84_17410	COG1482	cell wall glycoprotein biosynthetic process
CDO84_17415	COG0697	spore germination
CDO84_17420	COG0814	amino acid
CDO84_17430	COG2814	Major facilitator Superfamily
CDO84_17435	COG1316	TRANSCRIPTIONal
CDO84_17440	COG0561	phosphatase activity
CDO84_17445	COG0791	NLP P60 protein
CDO84_17455	COG2843	Capsule synthesis protein
CDO84_17465	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDO84_17470	COG1609	Transcriptional regulator
CDO84_17475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO84_17480	COG1869	D-ribose catabolic process
CDO84_17485	COG1129	ABC transporter
CDO84_17490	COG1172	Belongs to the binding-protein-dependent transport system permease family
CDO84_17495	COG1879	ABC-type sugar transport system periplasmic component
CDO84_17500	COG3103	Sh3 type 3 domain protein
CDO84_17510	COG2249	NAD(P)H dehydrogenase (quinone) activity
CDO84_17515	COG3527	Alpha-acetolactate decarboxylase
CDO84_17520	COG0028	Belongs to the TPP enzyme family
CDO84_17525	COG0583	DNA-binding transcription factor activity
CDO84_17530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CDO84_17545	COG5337	Spore coat protein CotH
CDO84_17555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDO84_17565	COG0405	Gamma-glutamyltransferase
CDO84_17570	COG1522	sequence-specific DNA binding
CDO84_17575	COG2059	Chromate
CDO84_17580	COG2059	Chromate
CDO84_17590	COG0655	NAD(P)H dehydrogenase (quinone) activity
CDO84_17595	COG0583	DNA-binding transcription factor activity
CDO84_17615	COG5444	nuclease activity
CDO84_17630	COG3878	Protein conserved in bacteria
CDO84_17635	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDO84_17640	COG4464	protein tyrosine phosphatase activity
CDO84_17645	COG0489	protein tyrosine kinase activity
CDO84_17650	COG3944	biosynthesis protein
CDO84_17660	COG4715	Zinc finger, swim domain protein
CDO84_17665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDO84_17670	COG0561	phosphatase activity
CDO84_17675	COG1349	DNA-binding transcription factor activity
CDO84_17680	COG0629	single-stranded DNA binding
CDO84_17695	COG3764	Sortase (surface protein transpeptidase)
CDO84_17705	COG3279	Response regulator of the LytR AlgR family
CDO84_17710	COG2972	Histidine kinase
CDO84_17710	COG0745	RESPONSE REGULATOR receiver
CDO84_17715	COG1970	mechanosensitive ion channel activity
CDO84_17720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDO84_17725	COG0457	Tetratricopeptide repeat
CDO84_17730	COG4786	Flagellar basal body rod
CDO84_17735	COG4786	Flagellar basal body rod
CDO84_17740	COG1077	Cell shape determining protein MreB Mrl
CDO84_17745	COG1609	Transcriptional regulator
CDO84_17755	COG1846	Transcriptional regulator
CDO84_17760	COG2814	Major facilitator Superfamily
CDO84_17765	COG3420	alginic acid biosynthetic process
CDO84_17770	COG1953	Uracil, thiamine, allantoin
CDO84_17775	COG0477	Major facilitator Superfamily
CDO84_17780	COG1335	isochorismatase
CDO84_17790	COG0004	ammonium transporteR
CDO84_17795	COG0347	Belongs to the P(II) protein family
CDO84_17800	COG0671	phosphoesterase, PA-phosphatase related
CDO84_17810	COG0739	heme binding
CDO84_17815	COG1247	-acetyltransferase
CDO84_17830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO84_17835	COG0789	Transcriptional regulator
CDO84_17845	COG2910	NAD(P)H-binding
CDO84_17850	COG1959	2 iron, 2 sulfur cluster binding
CDO84_17855	COG0804	urea catabolic process
CDO84_17860	COG0832	Belongs to the urease beta subunit family
CDO84_17865	COG0831	urea catabolic process
CDO84_17870	COG1122	ATPase activity
CDO84_17880	COG3237	CsbD-like
CDO84_17885	COG1994	Peptidase M50
CDO84_17890	COG0457	Tetratricopeptide repeat
CDO84_17895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDO84_17900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CDO84_17910	COG2304	oxidoreductase activity
CDO84_17915	COG2304	oxidoreductase activity
CDO84_17920	COG2385	sporulation resulting in formation of a cellular spore
CDO84_17925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDO84_17935	COG4836	Membrane
CDO84_17945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDO84_17950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDO84_17955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDO84_17960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDO84_17965	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO84_17970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDO84_17975	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDO84_17980	COG0356	it plays a direct role in the translocation of protons across the membrane
CDO84_17990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDO84_17995	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDO84_18000	COG4475	Protein of unknown function (DUF436)
CDO84_18005	COG0698	ribose 5-phosphate isomerase
CDO84_18010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDO84_18015	COG1971	Probably functions as a manganese efflux pump
CDO84_18020	COG0009	L-threonylcarbamoyladenylate synthase
CDO84_18025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CDO84_18045	COG2890	protein-(glutamine-N5) methyltransferase activity
CDO84_18050	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDO84_18055	COG0346	lactoylglutathione lyase activity
CDO84_18060	COG0789	Transcriptional regulator
CDO84_18065	COG0679	Auxin Efflux Carrier
CDO84_18070	COG0281	malic enzyme
CDO84_18075	COG1435	thymidine kinase activity
CDO84_18080	COG0254	rRNA binding
CDO84_18085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CDO84_18090	COG1494	fructose-1,6-bisphosphatase
CDO84_18095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDO84_18100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDO84_18105	COG0191	fructose-bisphosphate aldolase activity
CDO84_18110	COG2204	response regulator
CDO84_18115	COG4821	SIS domain
CDO84_18120	COG0504	CTP synthase activity
CDO84_18125	COG3343	RNA polymerase activity
CDO84_18130	COG1960	acyl-CoA dehydrogenase activity
CDO84_18135	COG2181	nitrate reductase activity
CDO84_18135	COG0247	lactate metabolic process
CDO84_18140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO84_18145	COG4294	response to UV
CDO84_18155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDO84_18160	COG1132	(ABC) transporter
CDO84_18165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CDO84_18175	COG2181	nitrate reductase activity
CDO84_18180	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CDO84_18185	COG1140	nitrate reductase beta subunit
CDO84_18190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CDO84_18195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO84_18205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDO84_18210	COG2223	nitrite transmembrane transporter activity
CDO84_18215	COG0018	arginyl-trna synthetase
CDO84_18220	COG4506	Protein conserved in bacteria
CDO84_18235	COG0535	radical SAM domain protein
CDO84_18245	COG1131	(ABC) transporter
CDO84_18250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDO84_18255	COG0612	Peptidase, M16
CDO84_18260	COG0612	Peptidase, M16
CDO84_18270	COG3391	amine dehydrogenase activity
CDO84_18275	COG3391	amine dehydrogenase activity
CDO84_18285	COG0457	Tetratricopeptide repeat
CDO84_18295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CDO84_18300	COG0010	Belongs to the arginase family
CDO84_18305	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CDO84_18310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CDO84_18325	COG1994	Peptidase M50
CDO84_18330	COG1942	4-Oxalocrotonate Tautomerase
CDO84_18335	COG1846	Transcriptional regulator
CDO84_18340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDO84_18350	COG0477	Major facilitator Superfamily
CDO84_18355	COG1959	2 iron, 2 sulfur cluster binding
CDO84_18360	COG3465	dGTPase activity
CDO84_18365	COG1078	dGTPase activity
CDO84_18370	COG4844	belongs to the
CDO84_18380	COG0697	spore germination
CDO84_18385	COG0095	Lipoate-protein ligase
CDO84_18390	COG0583	DNA-binding transcription factor activity
CDO84_18395	COG0280	phosphate acetyltransferase
CDO84_18405	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_18410	COG0436	Aminotransferase
CDO84_18415	COG2814	Major facilitator Superfamily
CDO84_18420	COG0151	Belongs to the GarS family
CDO84_18425	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_18430	COG1917	Cupin 2, conserved barrel domain protein
CDO84_18435	COG0077	Prephenate dehydratase
CDO84_18440	COG2814	Major facilitator Superfamily
CDO84_18445	COG0833	amino acid
CDO84_18450	COG4187	Peptidase family M20/M25/M40
CDO84_18455	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_18460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CDO84_18470	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CDO84_18475	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDO84_18480	COG1088	dTDP-glucose 4,6-dehydratase activity
CDO84_18485	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CDO84_18490	COG3980	spore coat polysaccharide biosynthesis protein
CDO84_18495	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CDO84_18500	COG2089	acid synthase
CDO84_18505	COG0456	acetyltransferase
CDO84_18510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDO84_18515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CDO84_18520	COG0463	Glycosyl transferase, family 2
CDO84_18535	COG2363	Small membrane protein
CDO84_18540	COG2233	PERMEase
CDO84_18550	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_18555	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CDO84_18560	COG1216	Glycosyl transferase, family 2
CDO84_18575	COG1695	Transcriptional regulator
CDO84_18580	COG0351	phosphomethylpyrimidine kinase
CDO84_18590	COG1621	beta-fructofuranosidase activity
CDO84_18595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_18595	COG1263	PTS System
CDO84_18600	COG2116	formate transmembrane transporter activity
CDO84_18605	COG3711	transcriptional antiterminator
CDO84_18615	COG1404	Belongs to the peptidase S8 family
CDO84_18620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CDO84_18625	COG0778	Nitroreductase
CDO84_18630	COG0772	Belongs to the SEDS family
CDO84_18645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CDO84_18650	COG1845	cytochrome c oxidase, subunit III
CDO84_18655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CDO84_18660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CDO84_18665	COG2261	transglycosylase associated protein
CDO84_18670	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CDO84_18675	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CDO84_18680	COG2246	polysaccharide biosynthetic process
CDO84_18685	COG1309	transcriptional regulator
CDO84_18695	COG3162	membrane
CDO84_18700	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CDO84_18705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CDO84_18710	COG2837	iron assimilation
CDO84_18715	COG2822	iron ion transport
CDO84_18720	COG0672	)-iron permease
CDO84_18725	COG0352	thiamine-phosphate diphosphorylase activity
CDO84_18730	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CDO84_18735	COG0583	DNA-binding transcription factor activity
CDO84_18740	COG1380	Effector of murein hydrolase LrgA
CDO84_18745	COG1346	cytolysis
CDO84_18750	COG2814	Major facilitator Superfamily
CDO84_18755	COG4895	conserved protein (DUF2196)
CDO84_18760	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CDO84_18765	COG0346	lactoylglutathione lyase activity
CDO84_18775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDO84_18785	COG1404	Belongs to the peptidase S8 family
CDO84_18795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_18795	COG1263	PTS System
CDO84_18800	COG3711	transcriptional antiterminator
CDO84_18805	COG1442	glycosyl transferase family 8
CDO84_18810	COG5522	Integral membrane protein (intg_mem_TP0381)
CDO84_18815	COG1846	Transcriptional regulator
CDO84_18820	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDO84_18825	COG2234	aminopeptidase activity
CDO84_18840	COG2814	Major facilitator Superfamily
CDO84_18845	COG2357	RelA SpoT domain protein
CDO84_18850	COG1575	Belongs to the MenA family. Type 1 subfamily
CDO84_18860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CDO84_18865	COG1696	Membrane protein involved in D-alanine export
CDO84_18870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDO84_18875	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CDO84_18880	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CDO84_18885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO84_18890	COG1486	melibiose metabolic process
CDO84_18895	COG1447	Phosphotransferase system cellobiose-specific component IIA
CDO84_18900	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDO84_18905	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CDO84_18910	COG3711	transcriptional antiterminator
CDO84_18910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CDO84_18920	COG2094	Belongs to the DNA glycosylase MPG family
CDO84_18925	COG0753	catalase activity
CDO84_18930	COG2814	Major facilitator Superfamily
CDO84_18935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CDO84_18940	COG1131	(ABC) transporter
CDO84_18960	COG1595	DNA-templated transcription, initiation
CDO84_18965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CDO84_18970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDO84_18975	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CDO84_18980	COG4988	ABC transporter
CDO84_18985	COG1294	oxidase, subunit
CDO84_18990	COG1271	oxidase subunit
CDO84_18995	COG3493	citrate carrier protein
CDO84_19000	COG0501	Belongs to the peptidase M48B family
CDO84_19010	COG0726	polysaccharide deacetylase
CDO84_19020	COG3842	ATPase activity
CDO84_19025	COG2508	Transcriptional regulator
CDO84_19030	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_19035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CDO84_19045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDO84_19055	COG4585	Histidine kinase
CDO84_19060	COG2197	response regulator
CDO84_19065	COG2195	Cleaves the N-terminal amino acid of tripeptides
CDO84_19075	COG4894	glucomannan catabolic process
CDO84_19080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDO84_19085	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDO84_19090	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_19095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CDO84_19100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CDO84_19105	COG2610	gluconate transmembrane transporter activity
CDO84_19110	COG0500	methyltransferase
CDO84_19115	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_19120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDO84_19135	COG0693	protein deglycase activity
CDO84_19135	COG0753	catalase activity
CDO84_19140	COG2851	Citrate transporter
CDO84_19145	COG2273	Hydrolase Family 16
CDO84_19150	COG3711	transcriptional antiterminator
CDO84_19160	COG2270	Major facilitator Superfamily
CDO84_19165	COG0513	Belongs to the DEAD box helicase family
CDO84_19170	COG2755	lipolytic protein G-D-S-L family
CDO84_19170	COG3401	FG-GAP repeat protein
CDO84_19230	COG0697	spore germination
CDO84_19245	COG0589	response to stress
CDO84_19250	COG2723	6-phospho-beta-galactosidase activity
CDO84_19255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_19255	COG2190	(PTS) system
CDO84_19255	COG1263	PTS System
CDO84_19300	COG5444	nuclease activity
CDO84_19315	COG3507	Belongs to the glycosyl hydrolase 43 family
CDO84_19330	COG2986	histidine ammonia-lyase
CDO84_19335	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CDO84_19340	COG1228	amidohydrolase
CDO84_19345	COG0010	Belongs to the arginase family
CDO84_19350	COG0833	amino acid
CDO84_19355	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CDO84_19360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CDO84_19365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDO84_19370	COG2390	Transcriptional regulator
CDO84_19380	COG3192	ethanolamine utilization protein
CDO84_19385	COG2079	MmgE PrpD family protein
CDO84_19395	COG1126	abc transporter atp-binding protein
CDO84_19400	COG0765	amino acid transport
CDO84_19405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CDO84_19420	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CDO84_19425	COG0561	phosphatase activity
CDO84_19455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDO84_19460	COG5294	Protein conserved in bacteria
CDO84_19465	COG0577	efflux transmembrane transporter activity
CDO84_19470	COG1136	(ABC) transporter
CDO84_19475	COG2205	protein histidine kinase activity
CDO84_19480	COG0745	RESPONSE REGULATOR receiver
CDO84_19485	COG0191	fructose-bisphosphate aldolase activity
CDO84_19490	COG1082	Xylose isomerase domain protein TIM barrel
CDO84_19495	COG1082	Xylose isomerase domain protein TIM barrel
CDO84_19500	COG0673	inositol 2-dehydrogenase activity
CDO84_19505	COG2814	Major facilitator Superfamily
CDO84_19510	COG1082	Xylose isomerase domain protein TIM barrel
CDO84_19515	COG3962	Belongs to the TPP enzyme family
CDO84_19520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CDO84_19530	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_19535	COG1349	DNA-binding transcription factor activity
CDO84_19540	COG0667	Aldo Keto reductase
CDO84_19570	COG2814	Major facilitator Superfamily
CDO84_19575	COG0326	Molecular chaperone. Has ATPase activity
CDO84_19585	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_19615	COG1309	transcriptional regulator
CDO84_19620	COG1012	belongs to the aldehyde dehydrogenase family
CDO84_19625	COG1714	RDD family
CDO84_19630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CDO84_19640	COG1714	RDD family
CDO84_19650	COG1917	Cupin 2, conserved barrel domain protein
CDO84_19655	COG1309	transcriptional regulator
CDO84_19660	COG1028	Short-chain dehydrogenase reductase Sdr
CDO84_19665	COG1846	Transcriptional regulator
CDO84_19670	COG1380	Effector of murein hydrolase LrgA
CDO84_19675	COG1346	cytolysis
CDO84_19685	COG5039	Polysaccharide pyruvyl transferase
CDO84_19690	COG1929	Belongs to the glycerate kinase type-1 family
CDO84_19695	COG1802	Transcriptional regulator
CDO84_19700	COG1070	Carbohydrate kinase
CDO84_19705	COG2610	gluconate transmembrane transporter activity
CDO84_19710	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDO84_19715	COG0450	alkyl hydroperoxide reductase
CDO84_19720	COG3634	alkyl hydroperoxide reductase activity
CDO84_19725	COG2723	6-phospho-beta-galactosidase activity
CDO84_19735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CDO84_19735	COG2190	(PTS) system
CDO84_19735	COG1263	PTS System
CDO84_19740	COG2188	Transcriptional regulator
CDO84_19750	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CDO84_19765	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CDO84_19780	COG1063	alcohol dehydrogenase
CDO84_19800	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CDO84_19805	COG0456	acetyltransferase
CDO84_19810	COG0457	Tetratricopeptide repeat
CDO84_19820	COG0010	Belongs to the arginase family
CDO84_19825	COG0833	amino acid
CDO84_19830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDO84_19855	COG5658	integral membrane protein
CDO84_19860	COG0640	Transcriptional regulator
CDO84_19865	COG3829	transcription factor binding
CDO84_19870	COG5002	protein histidine kinase activity
CDO84_19885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDO84_19890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CDO84_19895	COG4853	Protein conserved in bacteria
CDO84_19900	COG4863	YycH protein
CDO84_19905	COG5002	protein histidine kinase activity
CDO84_19910	COG0745	RESPONSE REGULATOR receiver
CDO84_19940	COG0346	lactoylglutathione lyase activity
CDO84_19945	COG0305	Participates in initiation and elongation during chromosome replication
CDO84_19960	COG3093	addiction module antidote protein HigA
CDO84_19965	COG2807	transmembrane transport
CDO84_19970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CDO84_19975	COG0359	binds to the 23S rRNA
CDO84_19980	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CDO84_19985	COG4241	membrane
CDO84_19995	COG5577	PFAM Coat F domain
CDO84_20000	COG1733	regulation of RNA biosynthetic process
CDO84_20005	COG1227	inorganic diphosphatase activity
CDO84_20020	COG2271	Major facilitator Superfamily
CDO84_20040	COG0071	Belongs to the small heat shock protein (HSP20) family
CDO84_20055	COG4319	ketosteroid isomerase
CDO84_20060	COG1357	PFAM Pentapeptide repeats (8 copies)
CDO84_20065	COG2814	Major facilitator Superfamily
CDO84_20070	COG0583	DNA-binding transcription factor activity
CDO84_20075	COG2153	protein acetylation
CDO84_20085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDO84_20090	COG1846	Transcriptional regulator
CDO84_20095	COG2153	protein acetylation
CDO84_20100	COG2364	Membrane
CDO84_20105	COG0456	acetyltransferase
CDO84_20110	COG2315	Protein conserved in bacteria
CDO84_20115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CDO84_20125	COG2814	Major facilitator Superfamily
CDO84_20135	COG0789	Transcriptional regulator
CDO84_20140	COG0697	spore germination
CDO84_20145	COG1331	Highly conserved protein containing a thioredoxin domain
CDO84_20150	COG1266	CAAX protease self-immunity
CDO84_20155	COG0477	Major facilitator Superfamily
CDO84_20155	COG2814	Major facilitator Superfamily
CDO84_20160	COG0110	maltose O-acetyltransferase activity
CDO84_20165	COG0346	lactoylglutathione lyase activity
CDO84_20170	COG1609	Transcriptional regulator
CDO84_20175	COG0708	Exodeoxyribonuclease III
CDO84_20180	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDO84_20185	COG0629	single-stranded DNA binding
CDO84_20190	COG0360	Binds together with S18 to 16S ribosomal RNA
CDO84_20195	COG0012	GTP binding
CDO84_20200	COG0243	molybdopterin cofactor binding
CDO84_20205	COG4481	Protein conserved in bacteria
CDO84_20210	COG3949	Membrane
CDO84_20220	COG1475	DNA binding
CDO84_20225	COG1192	Involved in chromosome partitioning
CDO84_20235	COG1475	DNA binding
CDO84_20240	COG0357	Ribosomal RNA small subunit methyltransferase G
CDO84_20245	COG0445	tRNA wobble uridine modification
CDO84_20250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDO84_20255	COG1847	R3H domain protein
CDO84_20260	COG0706	membrane insertase activity
CDO84_20265	COG0594	ribonuclease P activity
CDO84_20270	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDO84_20275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDO84_20280	COG0592	DNA-directed DNA polymerase activity
CDO84_20285	COG2501	S4 domain
CDO84_20290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDO84_20300	COG0187	DNA topoisomerase II activity
CDO84_20305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDO84_20340	COG0517	IMP dehydrogenase activity
CDO84_20340	COG0516	GMP reductase activity
CDO84_20345	COG1686	Belongs to the peptidase S11 family
CDO84_20350	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CDO84_20355	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CDO84_20360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDO84_20370	COG1428	Deoxynucleoside kinase
CDO84_20375	COG1428	Deoxynucleoside kinase
CDO84_20380	COG1388	LysM domain
CDO84_20380	COG3858	chitin binding
CDO84_20385	COG1335	isochorismatase
CDO84_20390	COG0590	tRNA wobble adenosine to inosine editing
CDO84_20400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDO84_20405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDO84_20410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDO84_20455	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CDO84_20460	COG3853	Toxic anion resistance protein (TelA)
CDO84_20465	COG1982	Orn Lys Arg decarboxylase major
CDO84_20470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDO84_20475	COG3870	Protein conserved in bacteria
CDO84_20480	COG1728	Protein conserved in bacteria
CDO84_20485	COG0470	DNA polymerase III
CDO84_20490	COG1774	PSP1 C-terminal conserved region
CDO84_20495	COG4467	Involved in initiation control of chromosome replication
CDO84_20500	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CDO84_20505	COG2827	Endonuclease containing a URI domain
CDO84_20510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDO84_20515	COG2002	toxin-antitoxin pair type II binding
CDO84_20520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO84_20520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDO84_20525	COG0084	hydrolase, TatD family'
CDO84_20530	COG3583	domain protein
CDO84_20530	COG3584	3D domain protein
CDO84_20535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CDO84_20540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDO84_20555	COG4466	Protein conserved in bacteria
CDO84_20565	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDO84_20570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDO84_20575	COG0251	oxidation-reduction process
CDO84_20580	COG2088	sporulation resulting in formation of a cellular spore
CDO84_20585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDO84_20590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDO84_20595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDO84_20600	COG0193	aminoacyl-tRNA hydrolase activity
CDO84_20610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDO84_20615	COG2002	toxin-antitoxin pair type II binding
CDO84_20620	COG2244	polysaccharide biosynthetic process
CDO84_20625	COG3956	TIGRFAM MazG family protein
CDO84_20630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CDO84_20645	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CDO84_20650	COG1098	S1 RNA binding domain
CDO84_20665	COG2208	phosphoserine phosphatase activity
CDO84_20670	COG2304	oxidoreductase activity
CDO84_20675	COG0515	serine threonine protein kinase
CDO84_20680	COG0037	tRNA processing
CDO84_20690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDO84_20695	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDO84_20700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDO84_20705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CDO84_20710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDO84_20715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDO84_20720	COG0512	Glutamine amidotransferase of anthranilate synthase
CDO84_20725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDO84_20730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDO84_20735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDO84_20740	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDO84_20745	COG1396	sequence-specific DNA binding
CDO84_20750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDO84_20755	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDO84_20840	COG4463	regulation of RNA biosynthetic process
CDO84_20845	COG3880	PFAM UvrB UvrC protein
CDO84_20850	COG3869	Catalyzes the specific phosphorylation of arginine residues in
CDO84_20855	COG0542	response to heat
CDO84_20860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDO84_20865	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CDO84_20870	COG4956	integral membrane protein (PIN domain superfamily)
CDO84_20875	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDO84_20880	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDO84_20885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDO84_20890	COG1045	serine acetyltransferase
CDO84_20895	COG0215	cysteine-tRNA ligase activity
CDO84_20900	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CDO84_20905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDO84_20910	COG3688	RNA-binding protein containing a PIN domain
CDO84_20915	COG1595	DNA-templated transcription, initiation
CDO84_20920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDO84_20925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CDO84_20930	COG0250	Participates in transcription elongation, termination and antitermination
CDO84_20935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDO84_20940	COG0081	regulation of translation
CDO84_20945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDO84_20950	COG0222	ribosome binding
CDO84_20955	COG2813	Specifically methylates the guanine in position
CDO84_20960	COG0085	RNA polymerase activity
CDO84_20965	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDO84_20970	COG1358	cellular component organization or biogenesis
CDO84_20975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDO84_20980	COG0049	tRNA binding
CDO84_20985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDO84_20990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDO84_20995	COG0596	Alpha beta hydrolase
CDO84_21000	COG0051	transcription antitermination factor activity, RNA binding
CDO84_21005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDO84_21010	COG0088	Forms part of the polypeptide exit tunnel
CDO84_21015	COG0089	rRNA binding
CDO84_21020	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDO84_21025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDO84_21030	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDO84_21035	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDO84_21040	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDO84_21045	COG0255	Belongs to the universal ribosomal protein uL29 family
CDO84_21050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDO84_21055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDO84_21065	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDO84_21075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDO84_21080	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDO84_21085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDO84_21090	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDO84_21095	COG1841	ribosomal large subunit assembly
CDO84_21100	COG0200	Binds to the 23S rRNA
CDO84_21105	COG0201	protein transport
CDO84_21110	COG0563	adenylate kinase activity
CDO84_21115	COG0024	Methionine aminopeptidase
CDO84_21120	COG2163	COG2163 Ribosomal protein L14E L6E L27E
CDO84_21125	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDO84_21130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDO84_21135	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDO84_21140	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDO84_21145	COG0202	RNA polymerase activity
CDO84_21150	COG0203	ribosomal protein L17
CDO84_21155	COG1122	ATPase activity
CDO84_21160	COG1122	ATPase activity
CDO84_21165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDO84_21170	COG0101	tRNA pseudouridine synthase activity
CDO84_21175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDO84_21180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDO84_21185	COG2226	methyltransferase
CDO84_21195	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDO84_21200	COG0489	protein tyrosine kinase activity
CDO84_21210	COG2194	sulfuric ester hydrolase activity
CDO84_21215	COG0726	polysaccharide deacetylase