locus-tag	class	description
GI482_00015	COG0596	Alpha beta hydrolase
GI482_00040	COG2814	Major facilitator Superfamily
GI482_00050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_00055	COG0318	PFAM AMP-dependent synthetase and ligase
GI482_00060	COG4221	oxidoreductase activity
GI482_00085	COG1525	nuclease
GI482_00090	COG1595	DNA-templated transcription, initiation
GI482_00110	COG0300	oxidoreductase activity
GI482_00140	COG1263	PTS System
GI482_00140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GI482_00155	COG3906	Belongs to the UPF0473 family
GI482_00165	COG1357	PFAM Pentapeptide repeats (8 copies)
GI482_00175	COG3844	kynureninase activity
GI482_00200	COG3739	integral membrane protein
GI482_00210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GI482_00235	COG0753	catalase activity
GI482_00260	COG0708	Exodeoxyribonuclease III
GI482_00275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GI482_00285	COG0714	Associated with various cellular activities
GI482_00290	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GI482_00295	COG1305	Transglutaminase-like
GI482_00300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GI482_00300	COG0519	Catalyzes the synthesis of GMP from XMP
GI482_00305	COG4974	Belongs to the 'phage' integrase family
GI482_00385	COG2252	PERMEase
GI482_00390	COG1247	-acetyltransferase
GI482_00420	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
GI482_00430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GI482_00435	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GI482_00440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GI482_00450	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GI482_00460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GI482_00465	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GI482_00475	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GI482_00485	COG0151	Belongs to the GarS family
GI482_00490	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GI482_00495	COG1470	cell adhesion involved in biofilm formation
GI482_00500	COG4496	protein, YerC YecD
GI482_00510	COG0210	DNA helicase
GI482_00520	COG4851	CamS sex pheromone cAM373 precursor
GI482_00550	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI482_00560	COG1597	lipid kinase activity
GI482_00565	COG1271	oxidase subunit
GI482_00570	COG1294	oxidase, subunit
GI482_00575	COG1011	Hydrolase
GI482_00580	COG0785	Cytochrome C biogenesis protein
GI482_00585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_00590	COG5002	protein histidine kinase activity
GI482_00595	COG0745	RESPONSE REGULATOR receiver
GI482_00610	COG1388	LysM domain
GI482_00620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GI482_00625	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GI482_00635	COG0351	phosphomethylpyrimidine kinase
GI482_00655	COG0583	DNA-binding transcription factor activity
GI482_00660	COG2814	Major facilitator Superfamily
GI482_00695	COG0300	oxidoreductase activity
GI482_00700	COG5522	Integral membrane protein (intg_mem_TP0381)
GI482_00710	COG0596	Alpha beta hydrolase
GI482_00715	COG1609	Transcriptional regulator
GI482_00720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GI482_00725	COG1869	D-ribose catabolic process
GI482_00730	COG1129	ABC transporter
GI482_00735	COG1172	Belongs to the binding-protein-dependent transport system permease family
GI482_00740	COG1879	ABC-type sugar transport system periplasmic component
GI482_00745	COG1268	BioY protein
GI482_00750	COG2205	protein histidine kinase activity
GI482_00750	COG0784	Response regulator, receiver
GI482_00755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GI482_00760	COG2208	phosphoserine phosphatase activity
GI482_00765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GI482_00785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI482_00790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_00800	COG1120	ATPase activity
GI482_00830	COG1396	sequence-specific DNA binding
GI482_00835	COG0477	Major facilitator Superfamily
GI482_00845	COG0346	lactoylglutathione lyase activity
GI482_00870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GI482_00875	COG1595	DNA-templated transcription, initiation
GI482_00890	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GI482_00920	COG3583	domain protein
GI482_00920	COG3584	3D domain protein
GI482_00935	COG2321	neutral zinc metallopeptidase
GI482_00940	COG1619	proteins homologs of microcin C7 resistance protein MccF
GI482_00945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GI482_00965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI482_00970	COG2233	PERMEase
GI482_00975	COG0393	Putative heavy-metal-binding
GI482_00995	COG0527	aspartate kinase activity
GI482_01005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GI482_01010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GI482_01035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GI482_01050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GI482_01065	COG0513	Belongs to the DEAD box helicase family
GI482_01070	COG2309	aminopeptidase activity
GI482_01090	COG3859	Proton-coupled thiamine transporter YuaJ
GI482_01095	COG0024	Methionine aminopeptidase
GI482_01110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_01115	COG0288	reversible hydration of carbon dioxide
GI482_01120	COG1077	Cell shape determining protein MreB Mrl
GI482_01130	COG2309	aminopeptidase activity
GI482_01135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GI482_01140	COG1360	Flagellar Motor Protein
GI482_01145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GI482_01155	COG4840	Belongs to the UPF0435 family
GI482_01160	COG1115	amino acid carrier protein
GI482_01170	COG1295	ribonuclease BN
GI482_01175	COG2217	Heavy metal translocating P-type atpase
GI482_01190	COG0477	Major facilitator Superfamily
GI482_01200	COG1063	alcohol dehydrogenase
GI482_01205	COG2323	membrane
GI482_01220	COG0519	Catalyzes the synthesis of GMP from XMP
GI482_01225	COG1115	amino acid carrier protein
GI482_01235	COG1012	belongs to the aldehyde dehydrogenase family
GI482_01240	COG4807	Protein conserved in bacteria
GI482_01245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GI482_01255	COG1090	epimerase
GI482_01275	COG1988	membrane-bound metal-dependent
GI482_01285	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_01295	COG3557	Belongs to the UPF0374 family
GI482_01300	COG1132	(ABC) transporter
GI482_01305	COG0444	Belongs to the ABC transporter superfamily
GI482_01310	COG4608	Belongs to the ABC transporter superfamily
GI482_01315	COG0747	negative chemotaxis
GI482_01330	COG4129	membrane
GI482_01340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GI482_01345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GI482_01350	COG0735	belongs to the Fur family
GI482_01355	COG0840	transmembrane signaling receptor activity
GI482_01490	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GI482_01510	COG3382	B3 4 domain protein
GI482_01515	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GI482_01520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GI482_01530	COG0656	L-ascorbic acid biosynthetic process
GI482_01550	COG2233	PERMEase
GI482_01555	COG0402	S-adenosylhomocysteine deaminase activity
GI482_01560	COG0564	pseudouridine synthase activity
GI482_01565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_01570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GI482_01575	COG3153	acetyltransferase
GI482_01575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI482_01580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GI482_01585	COG2203	Gaf domain
GI482_01585	COG4585	Histidine kinase
GI482_01590	COG2197	response regulator
GI482_01595	COG1253	flavin adenine dinucleotide binding
GI482_01605	COG1132	(ABC) transporter
GI482_01610	COG1132	(ABC) transporter
GI482_01635	COG1802	Transcriptional regulator
GI482_01640	COG1288	antiporter activity
GI482_01645	COG1473	amidohydrolase
GI482_01670	COG1024	Enoyl-CoA hydratase
GI482_01675	COG1595	DNA-templated transcription, initiation
GI482_01705	COG0420	3'-5' exonuclease activity
GI482_01710	COG4717	serine-type aminopeptidase activity
GI482_01720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GI482_01755	COG0537	adenosine 5'-monophosphoramidase activity
GI482_01760	COG1131	(ABC) transporter
GI482_01765	COG4473	ABC transporter
GI482_01775	COG2329	Antibiotic biosynthesis monooxygenase
GI482_01780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GI482_01795	COG1309	transcriptional regulator
GI482_01800	COG1511	domain protein
GI482_01805	COG1647	Serine aminopeptidase, S33
GI482_01825	COG0095	Lipoate-protein ligase
GI482_01845	COG0745	RESPONSE REGULATOR receiver
GI482_01850	COG2205	protein histidine kinase activity
GI482_01855	COG1136	(ABC) transporter
GI482_01860	COG0577	efflux transmembrane transporter activity
GI482_01865	COG0318	PFAM AMP-dependent synthetase and ligase
GI482_01870	COG0823	Involved in the tonB-independent uptake of proteins
GI482_01870	COG1506	peptidase
GI482_01870	COG4946	Tricorn protease homolog
GI482_01875	COG1113	amino acid transport
GI482_01885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GI482_01890	COG0390	transport system, permease component
GI482_01905	COG0471	metal ion transport
GI482_01905	COG0490	domain, Protein
GI482_01915	COG2226	methyltransferase
GI482_01920	COG1854	S-ribosylhomocysteine lyase activity
GI482_01925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GI482_01930	COG0626	cystathionine gamma-synthase activity
GI482_01935	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_01945	COG5504	Zn-dependent protease
GI482_01950	COG2226	methyltransferase
GI482_01970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GI482_01975	COG0765	amino acid transport
GI482_01980	COG1126	abc transporter atp-binding protein
GI482_02005	COG0745	RESPONSE REGULATOR receiver
GI482_02010	COG2205	protein histidine kinase activity
GI482_02015	COG1131	(ABC) transporter
GI482_02035	COG2084	Dehydrogenase
GI482_02050	COG2610	gluconate transmembrane transporter activity
GI482_02075	COG0668	transmembrane transport
GI482_02090	COG2155	Conserved Protein
GI482_02095	COG2226	methyltransferase
GI482_02140	COG2271	Major facilitator Superfamily
GI482_02145	COG0277	FAD linked oxidase domain protein
GI482_02150	COG1024	Enoyl-CoA hydratase
GI482_02155	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GI482_02175	COG0556	nucleotide-excision repair
GI482_02180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GI482_02185	COG3595	metallopeptidase activity
GI482_02195	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GI482_02205	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
GI482_02215	COG0110	maltose O-acetyltransferase activity
GI482_02220	COG1846	Transcriptional regulator
GI482_02225	COG0778	Nitroreductase
GI482_02240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GI482_02245	COG0131	Imidazoleglycerol-phosphate dehydratase
GI482_02250	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GI482_02255	COG0140	phosphoribosyl-ATP diphosphatase activity
GI482_02255	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GI482_02260	COG0457	Tetratricopeptide repeat
GI482_02265	COG0492	ferredoxin-NADP+ reductase activity
GI482_02270	COG1051	belongs to the nudix hydrolase family
GI482_02280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GI482_02290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GI482_02310	COG0753	catalase activity
GI482_02320	COG1214	PFAM Peptidase M22, glycoprotease
GI482_02320	COG0456	acetyltransferase
GI482_02340	COG2390	Transcriptional regulator
GI482_02355	COG0149	triose-phosphate isomerase activity
GI482_02360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GI482_02380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GI482_02390	COG0557	exoribonuclease II activity
GI482_02430	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
GI482_02500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_02510	COG0748	coenzyme F420 binding
GI482_02525	COG0697	spore germination
GI482_02550	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
GI482_02565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GI482_02570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GI482_02575	COG1012	belongs to the aldehyde dehydrogenase family
GI482_02580	COG0840	transmembrane signaling receptor activity
GI482_02635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GI482_02655	COG1285	pathogenesis
GI482_02660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GI482_02665	COG3944	biosynthesis protein
GI482_02670	COG0489	protein tyrosine kinase activity
GI482_02675	COG0438	transferase activity, transferring glycosyl groups
GI482_02685	COG0728	peptidoglycan biosynthetic process
GI482_02720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI482_02740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_02745	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI482_02745	COG1024	Enoyl-CoA hydratase
GI482_02750	COG0183	Belongs to the thiolase family
GI482_02755	COG1960	acyl-CoA dehydrogenase activity
GI482_02760	COG1393	Belongs to the ArsC family
GI482_02765	COG0509	glycine decarboxylation via glycine cleavage system
GI482_02770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GI482_02775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_02785	COG2011	ABC-type metal ion transport system permease component
GI482_02790	COG1464	Belongs to the NlpA lipoprotein family
GI482_02805	COG0396	ATPase activity
GI482_02810	COG0719	Fe-S assembly protein
GI482_02815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GI482_02820	COG0822	iron-sulfur transferase activity
GI482_02825	COG0719	Fe-S assembly protein
GI482_02835	COG1801	Protein of unknown function DUF72
GI482_02840	COG0730	response to heat
GI482_02845	COG0737	Belongs to the 5'-nucleotidase family
GI482_02855	COG1757	Na H antiporter
GI482_02860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GI482_02865	COG4470	Protein conserved in bacteria
GI482_02875	COG2445	Protein of unknown function DUF86
GI482_02880	COG0647	UMP catabolic process
GI482_02885	COG4844	belongs to the
GI482_02890	COG1252	NADH dehydrogenase
GI482_02895	COG4837	Protein of unknown function (DUF1462)
GI482_02900	COG0307	riboflavin synthase, alpha
GI482_02920	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GI482_02930	COG0316	Belongs to the HesB IscA family
GI482_02935	COG1252	NADH dehydrogenase
GI482_02955	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GI482_02960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GI482_02970	COG1320	monovalent cation:proton antiporter activity
GI482_02975	COG2212	antiporter activity
GI482_02980	COG1863	multisubunit Na H antiporter MnhE subunit
GI482_02985	COG0651	ATP synthesis coupled electron transport
GI482_02990	COG1006	Multisubunit Na H antiporter MnhC subunit
GI482_02995	COG2111	Na H antiporter
GI482_03000	COG2111	Na H antiporter
GI482_03000	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GI482_03015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI482_03020	COG2814	Major facilitator Superfamily
GI482_03025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GI482_03035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GI482_03050	COG0733	neurotransmitter:sodium symporter activity
GI482_03055	COG1595	DNA-templated transcription, initiation
GI482_03065	COG1098	S1 RNA binding domain
GI482_03070	COG3829	transcription factor binding
GI482_03075	COG1012	belongs to the aldehyde dehydrogenase family
GI482_03080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GI482_03090	COG1979	alcohol dehydrogenase
GI482_03100	COG1285	pathogenesis
GI482_03220	COG1575	Belongs to the MenA family. Type 1 subfamily
GI482_03225	COG1169	isochorismate synthase
GI482_03235	COG0596	Alpha beta hydrolase
GI482_03240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GI482_03245	COG0318	PFAM AMP-dependent synthetase and ligase
GI482_03250	COG0563	adenylate kinase activity
GI482_03275	COG0783	Belongs to the Dps family
GI482_03300	COG2816	NAD+ diphosphatase activity
GI482_03305	COG1506	peptidase
GI482_03320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GI482_03325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GI482_03335	COG0281	malic enzyme
GI482_03340	COG1755	Isoprenylcysteine carboxyl methyltransferase
GI482_03345	COG3424	synthase
GI482_03350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
GI482_03355	COG1242	4 iron, 4 sulfur cluster binding
GI482_03360	COG2814	Major facilitator Superfamily
GI482_03370	COG2318	DinB family
GI482_03375	COG0456	acetyltransferase
GI482_03380	COG0202	RNA polymerase activity
GI482_03395	COG1051	belongs to the nudix hydrolase family
GI482_03405	COG1522	sequence-specific DNA binding
GI482_03415	COG1335	isochorismatase
GI482_03445	COG1368	sulfuric ester hydrolase activity
GI482_03450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GI482_03455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GI482_03460	COG0495	leucyl-tRNA aminoacylation
GI482_03470	COG0512	Glutamine amidotransferase of anthranilate synthase
GI482_03475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GI482_03480	COG2081	HI0933 family
GI482_03485	COG2244	polysaccharide biosynthetic process
GI482_03490	COG1187	pseudouridine synthase activity
GI482_03495	COG1349	DNA-binding transcription factor activity
GI482_03500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI482_03520	COG1597	lipid kinase activity
GI482_03530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI482_03540	COG5584	Small secreted protein
GI482_03545	COG1363	Peptidase, m42
GI482_03550	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GI482_03560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_03565	COG4848	Belongs to the UPF0354 family
GI482_03570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GI482_03575	COG1674	ftsk spoiiie
GI482_03590	COG4980	gas vesicle protein
GI482_03600	COG1605	Chorismate mutase
GI482_03600	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GI482_03620	COG0346	lactoylglutathione lyase activity
GI482_03635	COG0123	including yeast histone deacetylase and acetoin utilization protein
GI482_03640	COG0517	IMP dehydrogenase activity
GI482_03645	COG0454	-acetyltransferase
GI482_03650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI482_03660	COG1113	amino acid transport
GI482_03675	COG0346	lactoylglutathione lyase activity
GI482_03680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GI482_03685	COG0765	amino acid transport
GI482_03690	COG1126	abc transporter atp-binding protein
GI482_03700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GI482_03730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI482_03735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_03740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_03745	COG1120	ATPase activity
GI482_03760	COG4585	Histidine kinase
GI482_03765	COG2197	response regulator
GI482_03775	COG5609	conserved protein (DUF2294)
GI482_03785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GI482_03805	COG1136	(ABC) transporter
GI482_03810	COG0577	efflux transmembrane transporter activity
GI482_03815	COG5002	protein histidine kinase activity
GI482_03815	COG3850	Histidine kinase
GI482_03835	COG2203	Gaf domain
GI482_03835	COG2199	diguanylate cyclase activity
GI482_03840	COG0626	cystathionine gamma-synthase activity
GI482_03845	COG1956	GAF domain-containing protein
GI482_03850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GI482_03855	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GI482_03860	COG1104	cysteine desulfurase activity
GI482_03875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GI482_03885	COG2962	Rard protein
GI482_03890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GI482_03895	COG0616	signal peptide processing
GI482_03900	COG1714	RDD family
GI482_03905	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GI482_03910	COG0827	DNA restriction-modification system
GI482_03915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GI482_03920	COG0589	response to stress
GI482_03930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI482_03935	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GI482_03940	COG0006	proline dipeptidase activity
GI482_03950	COG4109	DRTGG domain
GI482_03960	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GI482_03965	COG0587	DNA-directed DNA polymerase activity
GI482_03980	COG0825	malonyl-CoA metabolic process
GI482_03985	COG0205	6-phosphofructokinase activity
GI482_03995	COG3030	protein affecting phage T7 exclusion by the F plasmid
GI482_04000	COG0628	permease
GI482_04005	COG0372	Belongs to the citrate synthase family
GI482_04010	COG0538	isocitrate dehydrogenase activity
GI482_04025	COG0745	RESPONSE REGULATOR receiver
GI482_04030	COG5002	protein histidine kinase activity
GI482_04050	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_04060	COG0330	HflC and HflK could
GI482_04065	COG0330	HflC and HflK could
GI482_04070	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI482_04070	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GI482_04075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GI482_04080	COG0237	dephospho-CoA kinase activity
GI482_04085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GI482_04100	COG3611	Membrane attachment protein
GI482_04105	COG1484	DNA-dependent DNA replication
GI482_04110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GI482_04115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GI482_04160	COG1363	Peptidase, m42
GI482_04165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GI482_04175	COG1595	DNA-templated transcription, initiation
GI482_04185	COG0385	Bile acid
GI482_04190	COG0277	FAD linked oxidase domain protein
GI482_04205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GI482_04215	COG0072	phenylalanine-tRNA ligase activity
GI482_04215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GI482_04235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI482_04265	COG0456	acetyltransferase
GI482_04265	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GI482_04270	COG2070	2-Nitropropane dioxygenase
GI482_04295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GI482_04295	COG1796	DNA polymerase
GI482_04300	COG1193	negative regulation of DNA recombination
GI482_04305	COG3766	membrane
GI482_04310	COG0318	PFAM AMP-dependent synthetase and ligase
GI482_04315	COG1309	transcriptional regulator
GI482_04320	COG1024	Enoyl-CoA hydratase
GI482_04325	COG2086	electron transfer activity
GI482_04330	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GI482_04335	COG3118	belongs to the thioredoxin family
GI482_04350	COG1719	4-vinyl reductase, 4VR
GI482_04355	COG2009	succinate dehydrogenase
GI482_04360	COG1053	succinate dehydrogenase
GI482_04365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GI482_04370	COG0824	Thioesterase
GI482_04375	COG2197	response regulator
GI482_04380	COG1846	Transcriptional regulator
GI482_04400	COG0622	Phosphoesterase
GI482_04420	COG1476	TRANSCRIPTIONal
GI482_04430	COG2329	Antibiotic biosynthesis monooxygenase
GI482_04475	COG1233	COG1233 Phytoene dehydrogenase and related
GI482_04480	COG1562	ergosterol biosynthetic process
GI482_04500	COG2376	Dihydroxyacetone kinase
GI482_04505	COG5505	Protein of unknown function (DUF819)
GI482_04520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GI482_04525	COG1301	dicarboxylic acid transport
GI482_04540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI482_04545	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GI482_04550	COG1115	amino acid carrier protein
GI482_04565	COG0583	DNA-binding transcription factor activity
GI482_04575	COG0786	glutamate:sodium symporter activity
GI482_04580	COG3275	phosphorelay sensor kinase activity
GI482_04585	COG4753	response regulator
GI482_04585	COG2207	Transcriptional regulator
GI482_04595	COG1175	transmembrane transport
GI482_04600	COG0395	ABC-type sugar transport system, permease component
GI482_04620	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GI482_04625	COG1793	dna ligase
GI482_04625	COG3285	dna ligase
GI482_04650	COG0457	Tetratricopeptide repeat
GI482_04650	COG1477	protein flavinylation
GI482_04655	COG1649	PFAM Uncharacterised BCR, COG1649
GI482_04660	COG1472	Belongs to the glycosyl hydrolase 3 family
GI482_04665	COG1653	transport
GI482_04670	COG4209	transmembrane transport
GI482_04675	COG0395	ABC-type sugar transport system, permease component
GI482_04680	COG5578	integral membrane protein
GI482_04685	COG3876	Protein conserved in bacteria
GI482_04690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GI482_04695	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GI482_04700	COG1737	Transcriptional regulator
GI482_04705	COG2971	BadF BadG BcrA BcrD
GI482_04715	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GI482_04730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GI482_04735	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GI482_04745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GI482_04760	COG0113	porphobilinogen synthase activity
GI482_04780	COG0525	valine-tRNA ligase activity
GI482_04790	COG0189	ligase activity
GI482_04795	COG0285	dihydrofolate synthase activity
GI482_04800	COG0745	RESPONSE REGULATOR receiver
GI482_04800	COG3706	GGDEF domain
GI482_04825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI482_04860	COG0745	RESPONSE REGULATOR receiver
GI482_04860	COG3706	GGDEF domain
GI482_04865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GI482_04880	COG2003	Belongs to the UPF0758 family
GI482_04885	COG1077	Cell shape determining protein MreB Mrl
GI482_04890	COG1792	Involved in formation and maintenance of cell shape
GI482_04895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GI482_04900	COG0850	regulation of cytokinetic process
GI482_04905	COG2894	cell division
GI482_04915	COG1994	Peptidase M50
GI482_04925	COG2868	ribosomal protein
GI482_04950	COG0077	Prephenate dehydratase
GI482_04955	COG1827	regulation of RNA biosynthetic process
GI482_04985	COG0343	queuine tRNA-ribosyltransferase activity
GI482_04990	COG1862	Preprotein translocase
GI482_04995	COG2323	membrane
GI482_05000	COG2244	polysaccharide biosynthetic process
GI482_05010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI482_05010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI482_05015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GI482_05015	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GI482_05025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GI482_05035	COG3103	Sh3 type 3 domain protein
GI482_05035	COG0860	N-Acetylmuramoyl-L-alanine amidase
GI482_05035	COG4991	sh3 domain protein
GI482_05045	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GI482_05055	COG2814	Major facilitator Superfamily
GI482_05060	COG1280	lysine exporter protein (LysE YggA)
GI482_05070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GI482_05080	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GI482_05085	COG1959	2 iron, 2 sulfur cluster binding
GI482_05090	COG1104	cysteine desulfurase activity
GI482_05100	COG0457	Tetratricopeptide repeat
GI482_05105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GI482_05115	COG4472	Bacterial protein of unknown function (DUF965)
GI482_05125	COG3906	Belongs to the UPF0473 family
GI482_05130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GI482_05150	COG0572	uridine kinase
GI482_05155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GI482_05170	COG1191	sigma factor activity
GI482_05175	COG1183	phosphatidylcholine synthase activity
GI482_05185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
GI482_05190	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GI482_05200	COG1534	Rna-binding protein
GI482_05205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GI482_05210	COG1713	HD superfamily hydrolase involved in NAD metabolism
GI482_05215	COG0799	negative regulation of ribosome biogenesis
GI482_05220	COG2226	methyltransferase
GI482_05225	COG1596	polysaccharide export
GI482_05225	COG1555	photosystem II stabilization
GI482_05230	COG2131	deaminase
GI482_05235	COG0658	competence protein
GI482_05235	COG2333	competence protein COMEC
GI482_05245	COG1466	dna polymerase III delta subunit
GI482_05255	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GI482_05265	COG1876	peptidase activity
GI482_05280	COG0189	ligase activity
GI482_05285	COG0481	GTPase activity
GI482_05295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GI482_05310	COG0443	Heat shock 70 kDa protein
GI482_05320	COG2264	protein methyltransferase activity
GI482_05325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GI482_05330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GI482_05345	COG1030	water channel activity
GI482_05350	COG4864	UPF0365 protein
GI482_05365	COG1702	phosphate starvation-inducible protein PhoH
GI482_05370	COG1480	7TM receptor with intracellular HD hydrolase
GI482_05380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GI482_05395	COG1381	Involved in DNA repair and RecF pathway recombination
GI482_05400	COG0423	glycine-tRNA ligase activity
GI482_05405	COG0517	IMP dehydrogenase activity
GI482_05415	COG0358	DNA primase activity
GI482_05420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GI482_05430	COG1960	acyl-CoA dehydrogenase activity
GI482_05440	COG2384	SAM-dependent methyltransferase
GI482_05445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GI482_05460	COG0513	Belongs to the DEAD box helicase family
GI482_05475	COG1121	(ABC) transporter
GI482_05480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GI482_05485	COG0735	belongs to the Fur family
GI482_05495	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
GI482_05515	COG0704	Plays a role in the regulation of phosphate uptake
GI482_05520	COG2839	Protein conserved in bacteria
GI482_05535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GI482_05540	COG0573	inorganic phosphate transmembrane transporter activity
GI482_05545	COG0581	inorganic phosphate transmembrane transporter activity
GI482_05550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GI482_05555	COG0704	Plays a role in the regulation of phosphate uptake
GI482_05560	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GI482_05570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GI482_05575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GI482_05585	COG1368	sulfuric ester hydrolase activity
GI482_05600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI482_05615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GI482_05620	COG1459	type II secretion system
GI482_05625	COG4537	Required for transformation and DNA binding
GI482_05650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GI482_05655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GI482_05685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GI482_05690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI482_05700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GI482_05710	COG0006	proline dipeptidase activity
GI482_05745	COG0511	ligase activity, forming carbon-carbon bonds
GI482_05750	COG0439	Biotin carboxylase
GI482_05755	COG1302	Protein conserved in bacteria
GI482_05780	COG0142	geranyltranstransferase activity
GI482_05785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GI482_05790	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GI482_05800	COG0497	DNA recombination
GI482_05805	COG0750	zinc metalloprotease
GI482_05830	COG3829	transcription factor binding
GI482_05830	COG3290	protein histidine kinase activity
GI482_05840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GI482_05845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GI482_05850	COG0022	dehydrogenase e1 component
GI482_05855	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI482_05860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GI482_05875	COG0583	DNA-binding transcription factor activity
GI482_05880	COG0372	Belongs to the citrate synthase family
GI482_05890	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_05905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GI482_05915	COG2318	DinB family
GI482_05930	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GI482_05950	COG5002	protein histidine kinase activity
GI482_05960	COG0406	alpha-ribazole phosphatase activity
GI482_05980	COG2814	Major facilitator Superfamily
GI482_06015	COG0454	-acetyltransferase
GI482_06060	COG0667	Aldo Keto reductase
GI482_06070	COG1309	transcriptional regulator
GI482_06090	COG2814	Major facilitator Superfamily
GI482_06095	COG0583	DNA-binding transcription factor activity
GI482_06145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GI482_06160	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GI482_06170	COG1175	transmembrane transport
GI482_06205	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI482_06210	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI482_06210	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI482_06215	COG1703	isobutyryl-CoA mutase activity
GI482_06230	COG0346	lactoylglutathione lyase activity
GI482_06235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GI482_06240	COG2195	Cleaves the N-terminal amino acid of tripeptides
GI482_06250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GI482_06255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI482_06260	COG1234	tRNA 3'-trailer cleavage
GI482_06265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GI482_06275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI482_06280	COG0300	oxidoreductase activity
GI482_06290	COG3340	Belongs to the peptidase S51 family
GI482_06295	COG0346	lactoylglutathione lyase activity
GI482_06300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI482_06305	COG0438	transferase activity, transferring glycosyl groups
GI482_06310	COG0561	phosphatase activity
GI482_06315	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI482_06315	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GI482_06320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GI482_06320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GI482_06365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GI482_06370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GI482_06375	COG2169	Transcriptional regulator
GI482_06380	COG3396	Phenylacetate-CoA oxygenase
GI482_06410	COG1024	Enoyl-CoA hydratase
GI482_06420	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI482_06425	COG0183	Belongs to the thiolase family
GI482_06430	COG3327	negative regulation of DNA-templated transcription, initiation
GI482_06480	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI482_06500	COG3842	ATPase activity
GI482_06505	COG0179	Fumarylacetoacetate (FAA) hydrolase
GI482_06530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GI482_06535	COG1012	belongs to the aldehyde dehydrogenase family
GI482_06550	COG0753	catalase activity
GI482_06555	COG0702	epimerase
GI482_06575	COG2226	methyltransferase
GI482_06600	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_06610	COG2378	regulation of single-species biofilm formation
GI482_06615	COG2318	DinB family
GI482_06620	COG1253	flavin adenine dinucleotide binding
GI482_06625	COG0789	Transcriptional regulator
GI482_06640	COG1902	pentaerythritol trinitrate reductase activity
GI482_06650	COG0165	Argininosuccinate lyase
GI482_06660	COG0659	secondary active sulfate transmembrane transporter activity
GI482_06665	COG0589	response to stress
GI482_06670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_06680	COG1131	(ABC) transporter
GI482_06695	COG1051	belongs to the nudix hydrolase family
GI482_06700	COG0588	phosphoglycerate mutase activity
GI482_06710	COG1316	TRANSCRIPTIONal
GI482_06720	COG2814	Major facilitator Superfamily
GI482_06735	COG0693	protein deglycase activity
GI482_06740	COG1216	Glycosyl transferase, family 2
GI482_06740	COG0463	Glycosyl transferase, family 2
GI482_06755	COG0640	Transcriptional regulator
GI482_06780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GI482_06785	COG0134	indole-3-glycerol-phosphate synthase activity
GI482_06790	COG0135	phosphoribosylanthranilate isomerase activity
GI482_06795	COG0133	tryptophan synthase activity
GI482_06805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_06810	COG0204	Acyl-transferase
GI482_06830	COG0697	spore germination
GI482_06855	COG4974	Belongs to the 'phage' integrase family
GI482_06885	COG2182	Extracellular solute-binding protein
GI482_06890	COG1175	transmembrane transport
GI482_06895	COG3833	ABC-type maltose transport systems, permease component
GI482_06900	COG1874	Beta-galactosidase
GI482_06900	COG0366	Alpha amylase catalytic
GI482_06905	COG0366	Alpha amylase catalytic
GI482_06910	COG1609	Transcriptional regulator
GI482_06925	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GI482_06945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GI482_06955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GI482_07015	COG4974	Belongs to the 'phage' integrase family
GI482_07020	COG4974	Belongs to the 'phage' integrase family
GI482_07080	COG0653	protein targeting
GI482_07110	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GI482_07120	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GI482_07145	COG4974	Belongs to the 'phage' integrase family
GI482_07155	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GI482_07160	COG2205	protein histidine kinase activity
GI482_07195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GI482_07200	COG0187	DNA topoisomerase II activity
GI482_07205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GI482_07210	COG4841	protein insertion into membrane
GI482_07220	COG0824	Thioesterase
GI482_07230	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_07260	COG0411	ABC transporter
GI482_07270	COG2909	trisaccharide binding
GI482_07275	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_07290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GI482_07315	COG1970	mechanosensitive ion channel activity
GI482_07320	COG1999	signal sequence binding
GI482_07345	COG4846	Membrane protein involved in cytochrome C biogenesis
GI482_07350	COG2201	protein-glutamate methylesterase activity
GI482_07355	COG0785	Cytochrome C biogenesis protein
GI482_07360	COG1132	(ABC) transporter
GI482_07365	COG1132	(ABC) transporter
GI482_07370	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_07410	COG2153	protein acetylation
GI482_07420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GI482_07425	COG1078	dGTPase activity
GI482_07440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GI482_07445	COG2226	methyltransferase
GI482_07465	COG1191	sigma factor activity
GI482_07480	COG0346	lactoylglutathione lyase activity
GI482_07490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GI482_07490	COG0237	dephospho-CoA kinase activity
GI482_07495	COG0667	Aldo Keto reductase
GI482_07500	COG1960	acyl-CoA dehydrogenase activity
GI482_07510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GI482_07515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_07525	COG2808	Putative FMN-binding domain
GI482_07530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI482_07530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GI482_07545	COG0412	Dienelactone hydrolase
GI482_07585	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GI482_07595	COG0488	(ABC) transporter
GI482_07610	COG0628	permease
GI482_07615	COG1316	TRANSCRIPTIONal
GI482_07620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GI482_07625	COG2076	Multidrug Resistance protein
GI482_07630	COG2076	Multidrug Resistance protein
GI482_07645	COG0488	(ABC) transporter
GI482_07660	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_07665	COG1278	Cold shock
GI482_07675	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
GI482_07680	COG3853	Toxic anion resistance protein (TelA)
GI482_07685	COG4548	von Willebrand factor, type A
GI482_07690	COG0714	Associated with various cellular activities
GI482_07700	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI482_07705	COG0567	Dehydrogenase, E1 component
GI482_07710	COG5002	protein histidine kinase activity
GI482_07715	COG0745	RESPONSE REGULATOR receiver
GI482_07730	COG0534	Mate efflux family protein
GI482_07735	COG2340	Cysteine-rich secretory protein family
GI482_07745	COG0523	cobalamin synthesis protein
GI482_07750	COG0793	Belongs to the peptidase S41A family
GI482_07750	COG3409	Peptidoglycan-binding domain 1 protein
GI482_07755	COG0813	purine-nucleoside phosphorylase activity
GI482_07765	COG0840	transmembrane signaling receptor activity
GI482_07805	COG2755	lipolytic protein G-D-S-L family
GI482_07810	COG1307	EDD domain protein, DegV family
GI482_07820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GI482_07835	COG2521	methyltransferase
GI482_07835	COG2136	Putative SAM-dependent methyltransferase
GI482_07855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GI482_07875	COG1413	lyase activity
GI482_07880	COG0488	(ABC) transporter
GI482_07885	COG1418	mRNA catabolic process
GI482_07890	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GI482_07905	COG0328	RNA-DNA hybrid ribonuclease activity
GI482_07915	COG1278	Cold shock
GI482_07930	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GI482_07940	COG1272	protein, Hemolysin III
GI482_07955	COG1764	response to oxidative stress
GI482_07965	COG0745	RESPONSE REGULATOR receiver
GI482_07965	COG3706	GGDEF domain
GI482_07975	COG0411	ABC transporter
GI482_08005	COG2270	Major facilitator Superfamily
GI482_08010	COG0110	maltose O-acetyltransferase activity
GI482_08025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GI482_08030	COG0436	Aminotransferase
GI482_08040	COG1464	Belongs to the NlpA lipoprotein family
GI482_08050	COG2011	ABC-type metal ion transport system permease component
GI482_08055	COG1024	Enoyl-CoA hydratase
GI482_08065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GI482_08070	COG3546	catalase activity
GI482_08090	COG5577	PFAM Coat F domain
GI482_08100	COG0107	imidazoleglycerol-phosphate synthase activity
GI482_08105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GI482_08110	COG0493	'glutamate synthase
GI482_08115	COG0070	glutamate synthase
GI482_08115	COG0069	glutamate synthase activity
GI482_08115	COG0067	glutamate synthase
GI482_08120	COG0583	DNA-binding transcription factor activity
GI482_08135	COG2610	gluconate transmembrane transporter activity
GI482_08140	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GI482_08145	COG3395	kinase activity
GI482_08150	COG1349	DNA-binding transcription factor activity
GI482_08155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GI482_08160	COG0753	catalase activity
GI482_08170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GI482_08190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI482_08205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GI482_08210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GI482_08220	COG1199	ATP-dependent helicase activity
GI482_08225	COG0116	Belongs to the methyltransferase superfamily
GI482_08240	COG3599	regulation of cell shape
GI482_08245	COG3359	exonuclease
GI482_08250	COG1111	helicase
GI482_08250	COG1205	dead DEAH box helicase
GI482_08270	COG4499	WXG100 protein secretion system (Wss), protein YukC
GI482_08270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI482_08290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GI482_08295	COG3935	DnaD domain protein
GI482_08300	COG0017	Asparaginyl-tRNA synthetase
GI482_08315	COG1199	ATP-dependent helicase activity
GI482_08315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GI482_08320	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GI482_08335	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GI482_08335	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GI482_08340	COG0617	tRNA 3'-terminal CCA addition
GI482_08345	COG0438	transferase activity, transferring glycosyl groups
GI482_08360	COG1694	Mazg nucleotide pyrophosphohydrolase
GI482_08365	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI482_08370	COG2738	Putative neutral zinc metallopeptidase
GI482_08375	COG4347	Protein of unknown function (DUF1405)
GI482_08385	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GI482_08390	COG0723	plastoquinol--plastocyanin reductase activity
GI482_08400	COG5582	Belongs to the UPF0302 family
GI482_08405	COG0457	Tetratricopeptide repeat
GI482_08410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GI482_08415	COG0287	Prephenate dehydrogenase
GI482_08425	COG4401	Chorismate mutase type I
GI482_08440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GI482_08445	COG0105	UTP biosynthetic process
GI482_08450	COG0142	geranyltranstransferase activity
GI482_08480	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GI482_08500	COG1160	GTP binding
GI482_08505	COG0539	negative regulation of cytoplasmic translation
GI482_08510	COG0204	Acyl-transferase
GI482_08525	COG2959	enzyme of heme biosynthesis
GI482_08530	COG3409	Peptidoglycan-binding domain 1 protein
GI482_08530	COG3773	Cell wall hydrolase
GI482_08535	COG2339	peptidase activity
GI482_08550	COG0492	ferredoxin-NADP+ reductase activity
GI482_08555	COG1408	metallophosphoesterase
GI482_08565	COG1388	LysM domain
GI482_08570	COG0514	ATP-dependent DNA helicase (RecQ)
GI482_08580	COG1141	Ferredoxin
GI482_08585	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GI482_08595	COG1595	DNA-templated transcription, initiation
GI482_08600	COG5002	protein histidine kinase activity
GI482_08605	COG0745	RESPONSE REGULATOR receiver
GI482_08610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GI482_08615	COG1333	cytochrome c biogenesis protein
GI482_08620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_08625	COG1187	pseudouridine synthase activity
GI482_08630	COG1686	Belongs to the peptidase S11 family
GI482_08635	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GI482_08640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GI482_08645	COG1547	Domain of unknown function (DUF309)
GI482_08650	COG0456	acetyltransferase
GI482_08655	COG0019	diaminopimelate decarboxylase activity
GI482_08660	COG0697	spore germination
GI482_08680	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GI482_08685	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GI482_08690	COG4974	Belongs to the 'phage' integrase family
GI482_08695	COG0735	belongs to the Fur family
GI482_08710	COG0667	Aldo Keto reductase
GI482_08715	COG0563	adenylate kinase activity
GI482_08730	COG1653	transport
GI482_08735	COG0395	ABC-type sugar transport system, permease component
GI482_08740	COG4209	transmembrane transport
GI482_08745	COG5578	integral membrane protein
GI482_08755	COG2188	Transcriptional regulator
GI482_08790	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GI482_08795	COG1073	alpha beta
GI482_08800	COG3763	UPF0154 protein
GI482_08815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI482_08850	COG0860	N-Acetylmuramoyl-L-alanine amidase
GI482_08865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GI482_08900	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GI482_08945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI482_08960	COG0592	DNA-directed DNA polymerase activity
GI482_08990	COG1876	peptidase activity
GI482_09070	COG0174	glutamine synthetase
GI482_09075	COG0789	Transcriptional regulator
GI482_09080	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
GI482_09085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI482_09105	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GI482_09110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GI482_09115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GI482_09140	COG1131	(ABC) transporter
GI482_09145	COG2807	transmembrane transport
GI482_09155	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GI482_09225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GI482_09280	COG2252	PERMEase
GI482_09295	COG1309	transcriptional regulator
GI482_09300	COG2211	Major facilitator Superfamily
GI482_09310	COG5566	PFAM Mor transcription activator
GI482_09330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_09365	COG0456	acetyltransferase
GI482_09370	COG0789	Transcriptional regulator
GI482_09370	COG4978	Transcriptional regulator
GI482_09420	COG0745	RESPONSE REGULATOR receiver
GI482_09420	COG3706	GGDEF domain
GI482_09425	COG1725	Transcriptional regulator
GI482_09435	COG1131	(ABC) transporter
GI482_09440	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI482_09445	COG1131	(ABC) transporter
GI482_09475	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GI482_09480	COG1335	isochorismatase
GI482_09485	COG0494	nUDIX hydrolase
GI482_09500	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI482_09505	COG1051	belongs to the nudix hydrolase family
GI482_09515	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_09520	COG4166	transmembrane transport
GI482_09525	COG2027	D-alanyl-D-alanine carboxypeptidase
GI482_09530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI482_09540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_09580	COG0386	Belongs to the glutathione peroxidase family
GI482_09590	COG2318	DinB family
GI482_09610	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GI482_09615	COG2217	Heavy metal translocating P-type atpase
GI482_09650	COG0500	methyltransferase
GI482_09650	COG3615	Tellurite resistance protein tehB
GI482_09675	COG2211	Major facilitator Superfamily
GI482_09690	COG3279	Response regulator of the LytR AlgR family
GI482_09710	COG4550	Control of competence regulator ComK, YlbF/YmcA
GI482_09715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GI482_09720	COG1013	pyruvate-flavodoxin oxidoreductase activity
GI482_09725	COG0674	pyruvate-flavodoxin oxidoreductase activity
GI482_09725	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GI482_09730	COG2359	stage V sporulation protein S
GI482_09735	COG1692	metallophosphoesterase
GI482_09745	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GI482_09755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GI482_09760	COG1426	Protein conserved in bacteria
GI482_09770	COG0300	oxidoreductase activity
GI482_09775	COG0612	Peptidase, M16
GI482_09780	COG0612	Peptidase, M16
GI482_09805	COG2188	Transcriptional regulator
GI482_09810	COG1674	ftsk spoiiie
GI482_09815	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GI482_09825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GI482_09830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GI482_09835	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GI482_09845	COG0612	Peptidase, M16
GI482_09860	COG0196	riboflavin kinase activity
GI482_09870	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GI482_09875	COG1550	Protein conserved in bacteria
GI482_09885	COG1358	cellular component organization or biogenesis
GI482_09890	COG2740	Nucleic-acid-binding protein implicated in transcription termination
GI482_09895	COG0195	Participates in both transcription termination and antitermination
GI482_09905	COG2176	DNA-directed DNA polymerase activity
GI482_09910	COG0750	zinc metalloprotease
GI482_09920	COG4589	Belongs to the CDS family
GI482_09930	COG0233	cytoplasmic translational termination
GI482_09935	COG0528	UMP kinase activity
GI482_09960	COG1191	sigma factor activity
GI482_09970	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GI482_09975	COG1776	CheC inhibitor of MCP methylation
GI482_09980	COG0835	chemotaxis
GI482_09985	COG0643	Histidine kinase
GI482_09985	COG2198	Histidine kinase
GI482_09990	COG2201	protein-glutamate methylesterase activity
GI482_09995	COG0455	bacterial-type flagellum organization
GI482_10000	COG1419	protein localization to endoplasmic reticulum
GI482_10005	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GI482_10010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GI482_10015	COG1684	flagellar biosynthetic protein fliR
GI482_10020	COG1987	bacterial-type flagellum assembly
GI482_10025	COG1338	Plays a role in the flagellum-specific transport system
GI482_10030	COG3190	flagellar
GI482_10035	COG2201	protein-glutamate methylesterase activity
GI482_10040	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI482_10040	COG1776	CheC inhibitor of MCP methylation
GI482_10045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI482_10050	COG1580	Controls the rotational direction of flagella during chemotaxis
GI482_10055	COG1582	Flagellar protein (FlbD)
GI482_10060	COG4786	Flagellar basal body rod
GI482_10070	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GI482_10085	COG2882	bacterial-type flagellum organization
GI482_10090	COG1157	protein secretion by the type III secretion system
GI482_10100	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GI482_10105	COG1766	The M ring may be actively involved in energy transduction
GI482_10110	COG1677	Flagellar hook-basal body complex protein FliE
GI482_10115	COG1558	bacterial-type flagellum-dependent cell motility
GI482_10120	COG1815	bacterial-type flagellum-dependent cell motility
GI482_10130	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GI482_10140	COG4974	Belongs to the 'phage' integrase family
GI482_10150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GI482_10180	COG0726	polysaccharide deacetylase
GI482_10195	COG2323	membrane
GI482_10215	COG0758	DNA mediated transformation
GI482_10220	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GI482_10225	COG0045	succinate-CoA ligase (ADP-forming) activity
GI482_10230	COG2257	FlhB HrpN YscU SpaS Family
GI482_10240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GI482_10270	COG1837	Belongs to the UPF0109 family
GI482_10280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GI482_10290	COG0552	protein localization to endoplasmic reticulum
GI482_10295	COG1196	nuclear chromosome segregation
GI482_10300	COG0571	ribonuclease III activity
GI482_10305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GI482_10310	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_10315	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GI482_10325	COG1349	DNA-binding transcription factor activity
GI482_10330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GI482_10335	COG1760	l-serine dehydratase
GI482_10340	COG1760	l-serine dehydratase
GI482_10345	COG1461	Dihydroxyacetone kinase
GI482_10350	COG1302	Protein conserved in bacteria
GI482_10355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GI482_10370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GI482_10375	COG1162	GTPase activity
GI482_10380	COG0515	serine threonine protein kinase
GI482_10380	COG2815	serine threonine protein kinase
GI482_10385	COG0631	protein serine/threonine phosphatase activity
GI482_10390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GI482_10390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GI482_10400	COG0242	peptide deformylase activity
GI482_10405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GI482_10410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GI482_10420	COG0194	GDP metabolic process
GI482_10440	COG2267	carboxylic ester hydrolase activity
GI482_10455	COG0004	ammonium transporteR
GI482_10460	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI482_10465	COG0567	Dehydrogenase, E1 component
GI482_10470	COG0471	metal ion transport
GI482_10475	COG1305	Transglutaminase-like
GI482_10485	COG0583	DNA-binding transcription factor activity
GI482_10505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GI482_10515	COG0167	dihydroorotate dehydrogenase activity
GI482_10540	COG0540	Belongs to the ATCase OTCase family
GI482_10550	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GI482_10555	COG0564	pseudouridine synthase activity
GI482_10560	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GI482_10570	COG3599	regulation of cell shape
GI482_10580	COG0762	integral membrane protein
GI482_10585	COG1799	cell septum assembly
GI482_10590	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GI482_10600	COG1191	sigma factor activity
GI482_10605	COG1191	sigma factor activity
GI482_10615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GI482_10620	COG0849	cell division
GI482_10625	COG3856	small basic protein
GI482_10630	COG3879	Bacterial protein of unknown function (DUF881)
GI482_10635	COG3879	Bacterial protein of unknown function (DUF881)
GI482_10640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GI482_10645	COG0772	Belongs to the SEDS family
GI482_10655	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GI482_10660	COG0768	penicillin binding
GI482_10680	COG2001	Belongs to the MraZ family
GI482_10695	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GI482_10700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GI482_10705	COG0511	ligase activity, forming carbon-carbon bonds
GI482_10710	COG0439	Biotin carboxylase
GI482_10720	COG1024	Enoyl-CoA hydratase
GI482_10730	COG1399	metal-binding, possibly nucleic acid-binding protein
GI482_10740	COG3480	Lon protease (S16) C-terminal proteolytic domain
GI482_10750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GI482_10755	COG0742	ribosomal rna small subunit methyltransferase
GI482_10775	COG0584	glycerophosphoryl diester phosphodiesterase
GI482_10780	COG3679	Belongs to the UPF0342 family
GI482_10800	COG2340	Cysteine-rich secretory protein family
GI482_10820	COG3336	cytochrome c oxidase
GI482_10825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GI482_10840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GI482_10840	COG2010	Cytochrome c
GI482_10855	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GI482_10860	COG0772	Belongs to the SEDS family
GI482_10870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GI482_10875	COG4896	Protein conserved in bacteria
GI482_10895	COG0483	inositol monophosphate 1-phosphatase activity
GI482_10920	COG1982	Orn Lys Arg decarboxylase major
GI482_10925	COG1346	cytolysis
GI482_10930	COG1380	Effector of murein hydrolase LrgA
GI482_10945	COG0508	dehydrogenase complex catalyzes the overall conversion of
GI482_10950	COG0022	dehydrogenase e1 component
GI482_10975	COG0561	phosphatase activity
GI482_10985	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GI482_10995	COG0569	domain protein
GI482_11000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_11015	COG1176	ABC-type spermidine putrescine transport system, permease component I
GI482_11020	COG1177	transmembrane transport
GI482_11030	COG2814	Major facilitator Superfamily
GI482_11050	COG0714	Associated with various cellular activities
GI482_11065	COG1131	(ABC) transporter
GI482_11075	COG0583	DNA-binding transcription factor activity
GI482_11080	COG0517	IMP dehydrogenase activity
GI482_11085	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_11090	COG1126	abc transporter atp-binding protein
GI482_11100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GI482_11110	COG1063	alcohol dehydrogenase
GI482_11140	COG2207	Transcriptional regulator
GI482_11140	COG3708	Transcriptional regulator
GI482_11170	COG0784	Response regulator, receiver
GI482_11170	COG0835	chemotaxis
GI482_11175	COG2084	Dehydrogenase
GI482_11190	COG0714	Associated with various cellular activities
GI482_11205	COG4873	Protein conserved in bacteria
GI482_11220	COG1846	Transcriptional regulator
GI482_11225	COG5002	protein histidine kinase activity
GI482_11235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GI482_11240	COG0861	Integral membrane protein TerC family
GI482_11255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GI482_11260	COG1363	Peptidase, m42
GI482_11265	COG5002	protein histidine kinase activity
GI482_11275	COG1012	belongs to the aldehyde dehydrogenase family
GI482_11285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GI482_11290	COG2382	esterase
GI482_11325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GI482_11350	COG2239	Acts as a magnesium transporter
GI482_11355	COG0564	pseudouridine synthase activity
GI482_11365	COG2357	RelA SpoT domain protein
GI482_11375	COG4116	CYTH
GI482_11380	COG0741	lytic transglycosylase activity
GI482_11385	COG2346	COG2346, Truncated hemoglobins
GI482_11395	COG1164	Oligoendopeptidase f
GI482_11410	COG1393	Belongs to the ArsC family
GI482_11420	COG4608	Belongs to the ABC transporter superfamily
GI482_11425	COG0444	Belongs to the ABC transporter superfamily
GI482_11430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI482_11435	COG0601	transmembrane transport
GI482_11440	COG4166	transmembrane transport
GI482_11450	COG0180	Tryptophanyl-tRNA synthetase
GI482_11460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI482_11465	COG0601	transmembrane transport
GI482_11470	COG4608	Belongs to the ABC transporter superfamily
GI482_11480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GI482_11485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GI482_11495	COG0542	response to heat
GI482_11500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GI482_11505	COG2151	metal-sulfur cluster biosynthetic enzyme
GI482_11510	COG1073	alpha beta
GI482_11515	COG0561	phosphatase activity
GI482_11520	COG1307	EDD domain protein, DegV family
GI482_11530	COG1874	Beta-galactosidase
GI482_11530	COG0366	Alpha amylase catalytic
GI482_11545	COG2311	Membrane
GI482_11565	COG0398	Pfam SNARE associated Golgi protein
GI482_11570	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GI482_11585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GI482_11590	COG2011	ABC-type metal ion transport system permease component
GI482_11605	COG4897	Protein conserved in bacteria
GI482_11610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI482_11615	COG0793	Belongs to the peptidase S41A family
GI482_11615	COG3409	Peptidoglycan-binding domain 1 protein
GI482_11620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_11625	COG0791	NLP P60 protein
GI482_11625	COG3883	PFAM NLP P60 protein
GI482_11630	COG2177	Part of the ABC transporter FtsEX involved in
GI482_11635	COG2884	Cell division ATP-binding protein ftsE
GI482_11650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI482_11655	COG0840	transmembrane signaling receptor activity
GI482_11665	COG0653	protein targeting
GI482_11680	COG0791	NLP P60 protein
GI482_11685	COG0840	transmembrane signaling receptor activity
GI482_11690	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_11695	COG2514	catechol 2,3-dioxygenase activity
GI482_11700	COG0066	3-isopropylmalate dehydratase activity
GI482_11725	COG0440	acetolactate synthase activity
GI482_11730	COG0028	Belongs to the TPP enzyme family
GI482_11735	COG0129	dihydroxy-acid dehydratase activity
GI482_11745	COG0840	transmembrane signaling receptor activity
GI482_11750	COG0840	transmembrane signaling receptor activity
GI482_11755	COG0791	NLP P60 protein
GI482_11755	COG1388	LysM domain
GI482_11770	COG1516	flagellar protein fliS
GI482_11775	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GI482_11780	COG1334	flagellar protein FlaG
GI482_11785	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GI482_11790	COG1083	cytidylyl-transferase
GI482_11795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GI482_11805	COG2089	acid synthase
GI482_11810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GI482_11815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GI482_11820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI482_11835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GI482_11840	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GI482_11855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GI482_11860	COG1256	bacterial-type flagellum assembly
GI482_11860	COG4786	Flagellar basal body rod
GI482_11870	COG2747	anti-sigma28 factor FlgM
GI482_11880	COG1040	competence protein
GI482_11885	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GI482_11890	COG1307	EDD domain protein, DegV family
GI482_11905	COG2197	response regulator
GI482_11910	COG4585	Histidine kinase
GI482_11915	COG1739	Uncharacterized protein family UPF0029
GI482_11920	COG2340	Cysteine-rich secretory protein family
GI482_11930	COG2385	sporulation resulting in formation of a cellular spore
GI482_11930	COG2247	cell wall binding repeat
GI482_11940	COG0860	N-Acetylmuramoyl-L-alanine amidase
GI482_11945	COG1316	TRANSCRIPTIONal
GI482_11950	COG0438	transferase activity, transferring glycosyl groups
GI482_11955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GI482_11960	COG0297	glycogen (starch) synthase activity
GI482_12010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GI482_12030	COG0653	protein targeting
GI482_12040	COG0840	transmembrane signaling receptor activity
GI482_12050	COG1984	allophanate hydrolase subunit 2
GI482_12055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GI482_12060	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GI482_12065	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GI482_12075	COG0436	Aminotransferase
GI482_12080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GI482_12090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GI482_12095	COG1802	Transcriptional regulator
GI482_12100	COG0277	FAD linked oxidase domain protein
GI482_12125	COG1331	Highly conserved protein containing a thioredoxin domain
GI482_12150	COG4948	Mandelate Racemase Muconate Lactonizing
GI482_12160	COG0737	Belongs to the 5'-nucleotidase family
GI482_12170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GI482_12180	COG5002	protein histidine kinase activity
GI482_12180	COG3850	Histidine kinase
GI482_12185	COG0745	RESPONSE REGULATOR receiver
GI482_12195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GI482_12210	COG2610	gluconate transmembrane transporter activity
GI482_12215	COG1929	Belongs to the glycerate kinase type-1 family
GI482_12220	COG3835	regulator
GI482_12225	COG0791	NLP P60 protein
GI482_12230	COG0840	transmembrane signaling receptor activity
GI482_12235	COG1473	amidohydrolase
GI482_12240	COG4187	Peptidase family M20/M25/M40
GI482_12270	COG5444	nuclease activity
GI482_12290	COG1511	domain protein
GI482_12295	COG0433	COG0433 Predicted ATPase
GI482_12295	COG1674	ftsk spoiiie
GI482_12300	COG4499	WXG100 protein secretion system (Wss), protein YukC
GI482_12305	COG5417	Belongs to the EsaB family
GI482_12310	COG4842	Belongs to the WXG100 family
GI482_12315	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI482_12325	COG0318	PFAM AMP-dependent synthetase and ligase
GI482_12330	COG1309	transcriptional regulator
GI482_12335	COG1960	acyl-CoA dehydrogenase activity
GI482_12340	COG0668	transmembrane transport
GI482_12345	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_12350	COG3118	belongs to the thioredoxin family
GI482_12365	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
GI482_12380	COG0739	heme binding
GI482_12385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GI482_12400	COG0385	Bile acid
GI482_12405	COG2267	carboxylic ester hydrolase activity
GI482_12435	COG1988	membrane-bound metal-dependent
GI482_12445	COG1473	amidohydrolase
GI482_12450	COG1473	amidohydrolase
GI482_12455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GI482_12485	COG0656	L-ascorbic acid biosynthetic process
GI482_12490	COG0328	RNA-DNA hybrid ribonuclease activity
GI482_12520	COG0737	Belongs to the 5'-nucleotidase family
GI482_12525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI482_12530	COG0006	proline dipeptidase activity
GI482_12540	COG2508	Transcriptional regulator
GI482_12550	COG0577	efflux transmembrane transporter activity
GI482_12550	COG1136	(ABC) transporter
GI482_12555	COG1136	(ABC) transporter
GI482_12565	COG2909	trisaccharide binding
GI482_12575	COG1114	Component of the transport system for branched-chain amino acids
GI482_12585	COG0506	proline dehydrogenase activity
GI482_12590	COG3829	transcription factor binding
GI482_12595	COG1012	belongs to the aldehyde dehydrogenase family
GI482_12600	COG2356	endonuclease I
GI482_12605	COG0737	Belongs to the 5'-nucleotidase family
GI482_12615	COG0477	Major facilitator Superfamily
GI482_12625	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_12635	COG0704	Plays a role in the regulation of phosphate uptake
GI482_12645	COG0581	inorganic phosphate transmembrane transporter activity
GI482_12650	COG0573	inorganic phosphate transmembrane transporter activity
GI482_12655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GI482_12660	COG1595	DNA-templated transcription, initiation
GI482_12670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GI482_12710	COG2195	Cleaves the N-terminal amino acid of tripeptides
GI482_12715	COG4608	Belongs to the ABC transporter superfamily
GI482_12720	COG0444	Belongs to the ABC transporter superfamily
GI482_12725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI482_12730	COG0601	transmembrane transport
GI482_12740	COG1473	amidohydrolase
GI482_12745	COG2723	6-phospho-beta-galactosidase activity
GI482_12760	COG0395	ABC-type sugar transport system, permease component
GI482_12765	COG1175	transmembrane transport
GI482_12830	COG0438	transferase activity, transferring glycosyl groups
GI482_12865	COG0489	protein tyrosine kinase activity
GI482_12870	COG3944	biosynthesis protein
GI482_12915	COG0642	Histidine kinase
GI482_12920	COG0745	RESPONSE REGULATOR receiver
GI482_12925	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GI482_12925	COG2273	Hydrolase Family 16
GI482_12930	COG1215	transferase activity, transferring glycosyl groups
GI482_12935	COG0318	PFAM AMP-dependent synthetase and ligase
GI482_12940	COG1024	Enoyl-CoA hydratase
GI482_12960	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI482_12965	COG0183	Belongs to the thiolase family
GI482_12970	COG2610	gluconate transmembrane transporter activity
GI482_12975	COG1024	Enoyl-CoA hydratase
GI482_12985	COG1012	belongs to the aldehyde dehydrogenase family
GI482_12990	COG1454	alcohol dehydrogenase
GI482_13015	COG1914	H( )-stimulated, divalent metal cation uptake system
GI482_13020	COG1404	Belongs to the peptidase S8 family
GI482_13025	COG4608	Belongs to the ABC transporter superfamily
GI482_13030	COG0444	Belongs to the ABC transporter superfamily
GI482_13075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GI482_13080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GI482_13085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GI482_13090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI482_13100	COG1191	sigma factor activity
GI482_13130	COG0793	Belongs to the peptidase S41A family
GI482_13135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GI482_13155	COG4715	Zinc finger, swim domain protein
GI482_13160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI482_13165	COG0629	single-stranded DNA binding
GI482_13180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GI482_13190	COG4786	Flagellar basal body rod
GI482_13195	COG4786	Flagellar basal body rod
GI482_13200	COG1077	Cell shape determining protein MreB Mrl
GI482_13205	COG1609	Transcriptional regulator
GI482_13215	COG2385	sporulation resulting in formation of a cellular spore
GI482_13225	COG4836	Membrane
GI482_13240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GI482_13275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GI482_13285	COG4475	Protein of unknown function (DUF436)
GI482_13290	COG0698	ribose 5-phosphate isomerase
GI482_13310	COG0456	acetyltransferase
GI482_13340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_13355	COG1316	TRANSCRIPTIONal
GI482_13440	COG0009	L-threonylcarbamoyladenylate synthase
GI482_13450	COG2890	protein-(glutamine-N5) methyltransferase activity
GI482_13460	COG1435	thymidine kinase activity
GI482_13465	COG0254	rRNA binding
GI482_13470	COG0772	Belongs to the SEDS family
GI482_13500	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GI482_13505	COG1494	fructose-1,6-bisphosphatase
GI482_13510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GI482_13520	COG0191	fructose-bisphosphate aldolase activity
GI482_13525	COG2204	response regulator
GI482_13535	COG0504	CTP synthase activity
GI482_13545	COG1703	isobutyryl-CoA mutase activity
GI482_13545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI482_13545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GI482_13550	COG1309	transcriptional regulator
GI482_13555	COG1960	acyl-CoA dehydrogenase activity
GI482_13560	COG1960	acyl-CoA dehydrogenase activity
GI482_13565	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI482_13570	COG0183	Belongs to the thiolase family
GI482_13575	COG2181	nitrate reductase activity
GI482_13575	COG0247	lactate metabolic process
GI482_13600	COG2096	Adenosyltransferase
GI482_13615	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GI482_13625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GI482_13630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
GI482_13635	COG1120	ATPase activity
GI482_13640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_13645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI482_13660	COG3655	Transcriptional regulator
GI482_13670	COG0018	arginyl-trna synthetase
GI482_13680	COG0010	Belongs to the arginase family
GI482_13685	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GI482_13690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GI482_13710	COG3465	dGTPase activity
GI482_13715	COG1078	dGTPase activity
GI482_13735	COG0280	phosphate acetyltransferase
GI482_13745	COG3773	Cell wall hydrolase
GI482_13755	COG2363	Small membrane protein
GI482_13790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI482_13795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GI482_13805	COG0456	acetyltransferase
GI482_13840	COG5002	protein histidine kinase activity
GI482_13845	COG0745	RESPONSE REGULATOR receiver
GI482_13850	COG3321	synthase
GI482_13850	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_13850	COG0604	alcohol dehydrogenase
GI482_13860	COG2252	PERMEase
GI482_13865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GI482_13875	COG0156	8-amino-7-oxononanoate synthase activity
GI482_13885	COG2364	Membrane
GI482_13890	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GI482_13905	COG1388	LysM domain
GI482_13910	COG2217	Heavy metal translocating P-type atpase
GI482_13915	COG2608	mercury ion transmembrane transporter activity
GI482_13920	COG1937	Protein conserved in bacteria
GI482_13925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GI482_13930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GI482_13940	COG0501	Belongs to the peptidase M48B family
GI482_13960	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_13985	COG0494	nUDIX hydrolase
GI482_13990	COG4260	virion core protein, lumpy skin disease virus
GI482_13995	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GI482_14000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GI482_14005	COG1842	Phage shock protein A
GI482_14010	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_14020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GI482_14035	COG0431	NADPH-dependent FMN reductase
GI482_14040	COG0702	epimerase
GI482_14055	COG0488	(ABC) transporter
GI482_14065	COG1595	DNA-templated transcription, initiation
GI482_14070	COG1253	flavin adenine dinucleotide binding
GI482_14075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GI482_14090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GI482_14100	COG0778	Nitroreductase
GI482_14105	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GI482_14115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_14135	COG1120	ATPase activity
GI482_14140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI482_14145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_14150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_14155	COG0584	glycerophosphoryl diester phosphodiesterase
GI482_14165	COG1132	(ABC) transporter
GI482_14170	COG1132	(ABC) transporter
GI482_14175	COG0697	spore germination
GI482_14180	COG3300	MHYT domain
GI482_14180	COG5001	Diguanylate cyclase
GI482_14190	COG3610	response to peptide
GI482_14205	COG2031	fatty acid transporter
GI482_14210	COG1960	acyl-CoA dehydrogenase activity
GI482_14220	COG1012	belongs to the aldehyde dehydrogenase family
GI482_14235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GI482_14265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI482_14270	COG0601	transmembrane transport
GI482_14275	COG4172	Belongs to the ABC transporter superfamily
GI482_14280	COG0626	cystathionine gamma-synthase activity
GI482_14285	COG0626	cystathionine gamma-synthase activity
GI482_14290	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GI482_14310	COG1476	TRANSCRIPTIONal
GI482_14350	COG3546	catalase activity
GI482_14355	COG0726	polysaccharide deacetylase
GI482_14370	COG2027	D-alanyl-D-alanine carboxypeptidase
GI482_14385	COG2226	methyltransferase
GI482_14395	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GI482_14435	COG1215	transferase activity, transferring glycosyl groups
GI482_14450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GI482_14460	COG2814	Major facilitator Superfamily
GI482_14475	COG0737	Belongs to the 5'-nucleotidase family
GI482_14490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GI482_14495	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GI482_14510	COG3842	ATPase activity
GI482_14515	COG1840	ABC-type Fe3 transport system, periplasmic component
GI482_14530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI482_14535	COG2176	DNA-directed DNA polymerase activity
GI482_14560	COG3012	SEC-C Motif Domain Protein
GI482_14560	COG1405	negative regulation of cell septum assembly
GI482_14565	COG5002	protein histidine kinase activity
GI482_14565	COG3850	Histidine kinase
GI482_14585	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_14595	COG1250	3-hydroxyacyl-CoA dehydrogenase
GI482_14600	COG2610	gluconate transmembrane transporter activity
GI482_14650	COG1595	DNA-templated transcription, initiation
GI482_14670	COG3852	Histidine kinase
GI482_14675	COG4191	Histidine kinase
GI482_14695	COG3871	stress protein (general stress protein 26)
GI482_14700	COG1752	Esterase of the alpha-beta hydrolase superfamily
GI482_14710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GI482_14715	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_14720	COG2719	SpoVR family
GI482_14725	COG2718	Belongs to the UPF0229 family
GI482_14730	COG2766	serine protein kinase
GI482_14780	COG2986	histidine ammonia-lyase
GI482_14785	COG1376	ErfK ybiS ycfS ynhG family protein
GI482_14815	COG3377	Domain of unknown function (DUF1805)
GI482_14820	COG4412	M6 family metalloprotease domain protein
GI482_14820	COG1404	Belongs to the peptidase S8 family
GI482_14825	COG3361	conserved protein (COG2071)
GI482_14830	COG3584	3D domain protein
GI482_14830	COG1388	LysM domain
GI482_14840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI482_14855	COG3162	membrane
GI482_14860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI482_14870	COG1473	amidohydrolase
GI482_14875	COG2310	stress, protein
GI482_14880	COG2310	stress, protein
GI482_14895	COG1358	cellular component organization or biogenesis
GI482_14910	COG3853	Toxic anion resistance protein (TelA)
GI482_14915	COG2310	stress, protein
GI482_14920	COG2508	Transcriptional regulator
GI482_14925	COG3842	ATPase activity
GI482_14965	COG3458	cephalosporin-C deacetylase activity
GI482_14970	COG0673	inositol 2-dehydrogenase activity
GI482_14980	COG0395	ABC-type sugar transport system, permease component
GI482_14995	COG5578	integral membrane protein
GI482_15005	COG0730	response to heat
GI482_15010	COG0425	Belongs to the sulfur carrier protein TusA family
GI482_15015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI482_15015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI482_15025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI482_15025	COG0425	Belongs to the sulfur carrier protein TusA family
GI482_15030	COG0425	Belongs to the sulfur carrier protein TusA family
GI482_15030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GI482_15040	COG2210	Belongs to the sulfur carrier protein TusA family
GI482_15045	COG1937	Protein conserved in bacteria
GI482_15050	COG0697	spore germination
GI482_15060	COG2124	cytochrome p450
GI482_15080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GI482_15115	COG0559	Belongs to the binding-protein-dependent transport system permease family
GI482_15120	COG1022	Amp-dependent synthetase and ligase
GI482_15130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GI482_15135	COG2200	EAL domain
GI482_15145	COG0596	Alpha beta hydrolase
GI482_15150	COG4876	unkown
GI482_15165	COG2391	methyltransferase activity
GI482_15170	COG0425	Belongs to the sulfur carrier protein TusA family
GI482_15175	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GI482_15205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI482_15210	COG3361	conserved protein (COG2071)
GI482_15215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GI482_15220	COG1902	pentaerythritol trinitrate reductase activity
GI482_15230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI482_15240	COG2304	oxidoreductase activity
GI482_15280	COG1070	Carbohydrate kinase
GI482_15290	COG5578	integral membrane protein
GI482_15295	COG0395	ABC-type sugar transport system, permease component
GI482_15310	COG1940	carbohydrate kinase activity
GI482_15315	COG3507	Belongs to the glycosyl hydrolase 43 family
GI482_15330	COG1744	ABC transporter substrate-binding protein PnrA-like
GI482_15335	COG5278	phosphoserine phosphatase activity
GI482_15335	COG0840	transmembrane signaling receptor activity
GI482_15340	COG1966	Carbon starvation protein
GI482_15360	COG3181	Tripartite tricarboxylate transporter family receptor
GI482_15365	COG1053	succinate dehydrogenase
GI482_15370	COG0583	DNA-binding transcription factor activity
GI482_15405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GI482_15425	COG1288	antiporter activity
GI482_15435	COG0559	Belongs to the binding-protein-dependent transport system permease family
GI482_15460	COG2368	4-hydroxyphenylacetate
GI482_15470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GI482_15475	COG1309	transcriptional regulator
GI482_15495	COG3448	diguanylate cyclase activity
GI482_15495	COG4175	Glycine betaine
GI482_15500	COG4176	ABC-type proline glycine betaine transport system permease component
GI482_15510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GI482_15520	COG4721	ABC-type cobalt transport system, permease component
GI482_15525	COG1122	ATPase activity
GI482_15530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GI482_15550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GI482_15555	COG1309	transcriptional regulator
GI482_15575	COG1131	(ABC) transporter
GI482_15580	COG0745	RESPONSE REGULATOR receiver
GI482_15585	COG2205	protein histidine kinase activity
GI482_15600	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GI482_15605	COG0716	FMN binding
GI482_15610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GI482_15615	COG2311	Membrane
GI482_15620	COG0745	RESPONSE REGULATOR receiver
GI482_15625	COG2205	protein histidine kinase activity
GI482_15630	COG1968	undecaprenyl-diphosphatase activity
GI482_15635	COG0586	Pfam SNARE associated Golgi protein
GI482_15660	COG4585	Histidine kinase
GI482_15665	COG2197	response regulator
GI482_15675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GI482_15710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GI482_15720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GI482_15725	COG2224	Isocitrate lyase
GI482_15730	COG3279	Response regulator of the LytR AlgR family
GI482_15750	COG1595	DNA-templated transcription, initiation
GI482_15765	COG0697	spore germination
GI482_15770	COG0166	Belongs to the GPI family
GI482_15775	COG0460	homoserine dehydrogenase
GI482_15785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GI482_15805	COG1714	RDD family
GI482_15820	COG0697	spore germination
GI482_15825	COG1511	domain protein
GI482_15855	COG0628	permease
GI482_15875	COG0514	ATP-dependent DNA helicase (RecQ)
GI482_15885	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GI482_15895	COG0640	Transcriptional regulator
GI482_15900	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GI482_15905	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI482_15925	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_15930	COG2267	carboxylic ester hydrolase activity
GI482_15940	COG4607	ABC-type enterochelin transport system periplasmic component
GI482_15945	COG4604	ABC transporter, ATP-binding protein
GI482_15950	COG4605	iron ion homeostasis
GI482_15955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GI482_15985	COG1473	amidohydrolase
GI482_15990	COG4895	conserved protein (DUF2196)
GI482_16000	COG1278	Cold shock
GI482_16025	COG1473	amidohydrolase
GI482_16035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GI482_16055	COG2188	Transcriptional regulator
GI482_16090	COG0395	ABC-type sugar transport system, permease component
GI482_16095	COG1175	transmembrane transport
GI482_16100	COG3842	ATPase activity
GI482_16105	COG0584	glycerophosphoryl diester phosphodiesterase
GI482_16110	COG1671	Belongs to the UPF0178 family
GI482_16120	COG1116	anion transmembrane transporter activity
GI482_16125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GI482_16135	COG0037	tRNA processing
GI482_16135	COG0590	tRNA wobble adenosine to inosine editing
GI482_16140	COG0419	ATPase involved in DNA repair
GI482_16145	COG0420	3'-5' exonuclease activity
GI482_16150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GI482_16155	COG3239	Fatty acid desaturase
GI482_16160	COG4585	Histidine kinase
GI482_16165	COG2197	response regulator
GI482_16175	COG1408	metallophosphoesterase
GI482_16190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI482_16195	COG1131	(ABC) transporter
GI482_16310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GI482_16315	COG1396	sequence-specific DNA binding
GI482_16320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GI482_16325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GI482_16330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GI482_16335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GI482_16345	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GI482_16350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GI482_16370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GI482_16385	COG2208	phosphoserine phosphatase activity
GI482_16415	COG1098	S1 RNA binding domain
GI482_16435	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GI482_16440	COG3956	TIGRFAM MazG family protein
GI482_16445	COG2244	polysaccharide biosynthetic process
GI482_16450	COG2002	toxin-antitoxin pair type II binding
GI482_16455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GI482_16465	COG0193	aminoacyl-tRNA hydrolase activity
GI482_16475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GI482_16480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GI482_16490	COG0251	oxidation-reduction process
GI482_16495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GI482_16500	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GI482_16510	COG4466	Protein conserved in bacteria
GI482_16525	COG3584	3D domain protein
GI482_16525	COG3583	domain protein
GI482_16530	COG0084	hydrolase, TatD family'
GI482_16555	COG2002	toxin-antitoxin pair type II binding
GI482_16560	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GI482_16570	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GI482_16575	COG4467	Involved in initiation control of chromosome replication
GI482_16580	COG1774	PSP1 C-terminal conserved region
GI482_16585	COG0470	DNA polymerase III
GI482_16590	COG1728	Protein conserved in bacteria
GI482_16595	COG3870	Protein conserved in bacteria
GI482_16605	COG1982	Orn Lys Arg decarboxylase major
GI482_16635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GI482_16645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GI482_16660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_16665	COG1428	Deoxynucleoside kinase
GI482_16670	COG1428	Deoxynucleoside kinase
GI482_16675	COG3858	chitin binding
GI482_16675	COG1388	LysM domain
GI482_16680	COG0590	tRNA wobble adenosine to inosine editing
GI482_16685	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GI482_16690	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GI482_16695	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GI482_16700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GI482_16710	COG0516	GMP reductase activity
GI482_16710	COG0517	IMP dehydrogenase activity
GI482_16735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GI482_16740	COG0187	DNA topoisomerase II activity
GI482_16750	COG2501	S4 domain
GI482_16755	COG0592	DNA-directed DNA polymerase activity
GI482_16765	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GI482_16770	COG0594	ribonuclease P activity
GI482_16775	COG0706	membrane insertase activity
GI482_16780	COG1847	R3H domain protein
GI482_16805	COG1192	Involved in chromosome partitioning
GI482_16810	COG1475	DNA binding
GI482_16815	COG1811	Na channel or pump
GI482_16825	COG0668	transmembrane transport
GI482_16830	COG4481	Protein conserved in bacteria
GI482_16835	COG0012	GTP binding
GI482_16850	COG0629	single-stranded DNA binding
GI482_16855	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GI482_16865	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
GI482_16875	COG0305	Participates in initiation and elongation during chromosome replication
GI482_16885	COG0741	lytic transglycosylase activity
GI482_16885	COG1196	nuclear chromosome segregation
GI482_16885	COG0739	heme binding
GI482_16890	COG0745	RESPONSE REGULATOR receiver
GI482_16895	COG5002	protein histidine kinase activity
GI482_16905	COG4853	Protein conserved in bacteria
GI482_16910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GI482_16915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GI482_16945	COG2003	Belongs to the UPF0758 family
GI482_16980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GI482_17030	COG3773	Cell wall hydrolase
GI482_17045	COG3541	Predicted nucleotidyltransferase
GI482_17055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GI482_17065	COG4720	Psort location CytoplasmicMembrane, score
GI482_17070	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_17075	COG1595	DNA-templated transcription, initiation
GI482_17085	COG0726	polysaccharide deacetylase
GI482_17100	COG0450	alkyl hydroperoxide reductase
GI482_17115	COG1388	LysM domain
GI482_17115	COG3858	chitin binding
GI482_17125	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_17130	COG4708	membrane
GI482_17140	COG1533	DNA photolyase activity
GI482_17150	COG2340	Cysteine-rich secretory protein family
GI482_17160	COG0765	amino acid transport
GI482_17165	COG1126	abc transporter atp-binding protein
GI482_17170	COG0596	Alpha beta hydrolase
GI482_17175	COG3706	GGDEF domain
GI482_17185	COG2329	Antibiotic biosynthesis monooxygenase
GI482_17195	COG2200	EAL domain
GI482_17200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GI482_17205	COG0805	protein transport
GI482_17230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GI482_17235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GI482_17235	COG1321	iron dependent repressor
GI482_17240	COG1121	(ABC) transporter
GI482_17245	COG0803	Belongs to the bacterial solute-binding protein 9 family
GI482_17285	COG0427	acetyl-CoA hydrolase
GI482_17290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GI482_17295	COG1012	belongs to the aldehyde dehydrogenase family
GI482_17310	COG2340	Cysteine-rich secretory protein family
GI482_17315	COG2032	superoxide dismutase activity
GI482_17320	COG2814	Major facilitator Superfamily
GI482_17325	COG1846	Transcriptional regulator
GI482_17335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GI482_17355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GI482_17375	COG1187	pseudouridine synthase activity
GI482_17385	COG1607	acyl-coa hydrolase
GI482_17400	COG1690	Belongs to the RtcB family
GI482_17405	COG0598	Magnesium transport protein CorA
GI482_17410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GI482_17425	COG2362	D-Aminopeptidase
GI482_17430	COG0601	transmembrane transport
GI482_17435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI482_17440	COG0444	Belongs to the ABC transporter superfamily
GI482_17445	COG4166	transmembrane transport
GI482_17450	COG1619	proteins homologs of microcin C7 resistance protein MccF
GI482_17455	COG4948	Mandelate Racemase Muconate Lactonizing
GI482_17460	COG0791	NLP P60 protein
GI482_17465	COG4608	Belongs to the ABC transporter superfamily
GI482_17475	COG1725	Transcriptional regulator
GI482_17480	COG1131	(ABC) transporter
GI482_17485	COG1131	(ABC) transporter
GI482_17490	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
GI482_17500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GI482_17500	COG0456	acetyltransferase
GI482_17515	COG3869	Catalyzes the specific phosphorylation of arginine residues in
GI482_17520	COG0542	response to heat
GI482_17525	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GI482_17530	COG4956	integral membrane protein (PIN domain superfamily)
GI482_17550	COG1045	serine acetyltransferase
GI482_17565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GI482_17570	COG3688	RNA-binding protein containing a PIN domain
GI482_17580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GI482_17585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GI482_17590	COG0250	Participates in transcription elongation, termination and antitermination
GI482_17615	COG2813	Specifically methylates the guanine in position
GI482_17630	COG1358	cellular component organization or biogenesis
GI482_17640	COG0049	tRNA binding
GI482_17655	COG0745	RESPONSE REGULATOR receiver
GI482_17660	COG0642	Histidine kinase
GI482_17665	COG1136	(ABC) transporter
GI482_17670	COG0577	efflux transmembrane transporter activity
GI482_17675	COG2056	Na+-H+ antiporter family
GI482_17680	COG0051	transcription antitermination factor activity, RNA binding
GI482_17700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GI482_17725	COG0255	Belongs to the universal ribosomal protein uL29 family
GI482_17730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GI482_17760	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GI482_17785	COG0201	protein transport
GI482_17795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GI482_17815	COG0202	RNA polymerase activity
GI482_17825	COG1122	ATPase activity
GI482_17835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GI482_17845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GI482_17860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_17865	COG2211	Major facilitator Superfamily
GI482_17870	COG0860	N-Acetylmuramoyl-L-alanine amidase
GI482_17875	COG0489	protein tyrosine kinase activity
GI482_17885	COG2194	sulfuric ester hydrolase activity
GI482_17955	COG1595	DNA-templated transcription, initiation
GI482_17960	COG5662	AntiSigma factor
GI482_17965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GI482_17970	COG4856	YbbR-like protein
GI482_17980	COG0693	protein deglycase activity
GI482_17985	COG1522	sequence-specific DNA binding
GI482_17995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GI482_18000	COG0747	negative chemotaxis
GI482_18005	COG0444	Belongs to the ABC transporter superfamily
GI482_18010	COG4608	Belongs to the ABC transporter superfamily
GI482_18015	COG0405	Gamma-glutamyltransferase
GI482_18020	COG2059	Chromate
GI482_18025	COG2059	Chromate
GI482_18030	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GI482_18060	COG2814	Major facilitator Superfamily
GI482_18125	COG0640	Transcriptional regulator
GI482_18150	COG0477	Major facilitator Superfamily
GI482_18165	COG1028	Short-chain dehydrogenase reductase Sdr
GI482_18180	COG0431	NADPH-dependent FMN reductase
GI482_18185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GI482_18190	COG1733	regulation of RNA biosynthetic process
GI482_18200	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GI482_18205	COG0028	Belongs to the TPP enzyme family
GI482_18210	COG2824	Alkylphosphonate utilization operon protein PhnA
GI482_18215	COG0366	Alpha amylase catalytic
GI482_18220	COG1940	carbohydrate kinase activity
GI482_18225	COG0166	Belongs to the GPI family
GI482_18245	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GI482_18250	COG1122	ATPase activity
GI482_18255	COG4720	Psort location CytoplasmicMembrane, score
GI482_18285	COG4682	membrane
GI482_18300	COG0572	uridine kinase
GI482_18335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GI482_18370	COG0697	spore germination
GI482_18375	COG2814	Major facilitator Superfamily
GI482_18385	COG1846	Transcriptional regulator
GI482_18390	COG0386	Belongs to the glutathione peroxidase family
GI482_18405	COG0534	Mate efflux family protein
GI482_18410	COG5001	Diguanylate cyclase
GI482_18415	COG0436	Aminotransferase
GI482_18420	COG1136	(ABC) transporter
GI482_18425	COG0577	efflux transmembrane transporter activity
GI482_18430	COG0840	transmembrane signaling receptor activity
GI482_18435	COG0789	Transcriptional regulator
GI482_18470	COG5002	protein histidine kinase activity
GI482_18475	COG0745	RESPONSE REGULATOR receiver
GI482_18490	COG0446	pyridine nucleotide-disulphide oxidoreductase
GI482_18495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_18505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_18510	COG1307	EDD domain protein, DegV family
GI482_18540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GI482_18555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GI482_18575	COG0494	nUDIX hydrolase
GI482_18590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GI482_18610	COG0217	transcriptional regulatory protein
GI482_18640	COG2171	N-acyltransferase activity
GI482_18645	COG1473	amidohydrolase
GI482_18650	COG4106	trans-aconitate 2-methyltransferase activity
GI482_18655	COG0367	asparagine synthase
GI482_18660	COG1668	transmembrane transport
GI482_18665	COG4152	abc transporter atp-binding protein
GI482_18675	COG0456	acetyltransferase
GI482_18695	COG0018	arginyl-trna synthetase
GI482_18700	COG2311	Membrane
GI482_18710	COG5002	protein histidine kinase activity
GI482_18735	COG1695	Transcriptional regulator
GI482_18745	COG0789	Transcriptional regulator
GI482_18750	COG0406	alpha-ribazole phosphatase activity
GI482_18760	COG1834	amidinotransferase
GI482_18765	COG3403	YqcI/YcgG family
GI482_18770	COG1472	Belongs to the glycosyl hydrolase 3 family
GI482_18775	COG2323	membrane
GI482_18780	COG2223	nitrite transmembrane transporter activity
GI482_18790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GI482_18790	COG2111	Na H antiporter
GI482_18795	COG2111	Na H antiporter
GI482_18800	COG1006	Multisubunit Na H antiporter MnhC subunit
GI482_18805	COG0651	ATP synthesis coupled electron transport
GI482_18810	COG1863	multisubunit Na H antiporter MnhE subunit
GI482_18815	COG2212	antiporter activity
GI482_18825	COG1114	Component of the transport system for branched-chain amino acids
GI482_18830	COG1802	Transcriptional regulator
GI482_18840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GI482_18845	COG3011	Protein conserved in bacteria
GI482_18850	COG0492	ferredoxin-NADP+ reductase activity
GI482_18855	COG0322	excinuclease ABC activity
GI482_18880	COG0400	carboxylic ester hydrolase activity
GI482_18885	COG2409	Drug exporters of the RND superfamily
GI482_18895	COG0306	phosphate transporter
GI482_18900	COG1392	Phosphate transport regulator
GI482_18910	COG2268	Band 7 protein
GI482_18920	COG0114	fumarate hydratase activity
GI482_18930	COG1136	(ABC) transporter
GI482_18935	COG0577	efflux transmembrane transporter activity
GI482_18950	COG0318	PFAM AMP-dependent synthetase and ligase
GI482_18960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GI482_18965	COG1132	(ABC) transporter
GI482_18970	COG3104	oligopeptide transport
GI482_18980	COG0492	ferredoxin-NADP+ reductase activity
GI482_19005	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GI482_19010	COG0477	Major facilitator Superfamily
GI482_19015	COG2274	protein secretion by the type I secretion system
GI482_19015	COG3271	cysteine-type peptidase activity
GI482_19020	COG0427	acetyl-CoA hydrolase
GI482_19040	COG1959	2 iron, 2 sulfur cluster binding
GI482_19045	COG1227	inorganic diphosphatase activity
GI482_19050	COG1115	amino acid carrier protein
GI482_19055	COG0723	plastoquinol--plastocyanin reductase activity
GI482_19055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GI482_19065	COG1132	(ABC) transporter
GI482_19070	COG1132	(ABC) transporter
GI482_19085	COG1132	(ABC) transporter
GI482_19095	COG1473	amidohydrolase
GI482_19110	COG2353	YceI-like domain
GI482_19115	COG1733	regulation of RNA biosynthetic process
GI482_19120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GI482_19140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_19170	COG0346	lactoylglutathione lyase activity
GI482_19175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GI482_19185	COG3153	acetyltransferase
GI482_19200	COG1597	lipid kinase activity
GI482_19210	COG0706	membrane insertase activity
GI482_19220	COG2814	Major facilitator Superfamily
GI482_19225	COG1876	peptidase activity
GI482_19230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GI482_19235	COG1131	(ABC) transporter
GI482_19250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GI482_19280	COG0517	IMP dehydrogenase activity
GI482_19285	COG0772	Belongs to the SEDS family
GI482_19295	COG2076	Multidrug Resistance protein
GI482_19300	COG2076	Multidrug Resistance protein
GI482_19305	COG1181	Belongs to the D-alanine--D-alanine ligase family
GI482_19310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GI482_19315	COG0596	Alpha beta hydrolase
GI482_19320	COG0513	Belongs to the DEAD box helicase family
GI482_19325	COG3402	PFAM membrane-flanked domain
GI482_19330	COG3428	Bacterial PH domain
GI482_19335	COG0705	Rhomboid family
GI482_19340	COG0736	holo-[acyl-carrier-protein] synthase activity
GI482_19345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GI482_19360	COG2337	Toxic component of a toxin-antitoxin (TA) module
GI482_19365	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_19370	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_19375	COG2172	sigma factor antagonist activity
GI482_19380	COG2208	phosphoserine phosphatase activity
GI482_19385	COG1366	Belongs to the anti-sigma-factor antagonist family
GI482_19390	COG2172	sigma factor antagonist activity
GI482_19395	COG1191	sigma factor activity
GI482_19405	COG2183	response to ionizing radiation
GI482_19410	COG3091	SprT-like family
GI482_19470	COG2207	Transcriptional regulator
GI482_19480	COG1131	(ABC) transporter
GI482_19495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GI482_19505	COG2133	pyrroloquinoline quinone binding
GI482_19515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GI482_19530	COG2720	vancomycin resistance protein
GI482_19535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GI482_19560	COG0653	protein targeting
GI482_19570	COG3290	protein histidine kinase activity
GI482_19575	COG4565	transcriptional regulatory protein
GI482_19580	COG3181	Tripartite tricarboxylate transporter family receptor
GI482_19595	COG0840	transmembrane signaling receptor activity
GI482_19625	COG0653	protein targeting
GI482_19635	COG1272	protein, Hemolysin III
GI482_19660	COG0494	nUDIX hydrolase
GI482_19730	COG5444	nuclease activity
GI482_19750	COG1414	Transcriptional regulator
GI482_19755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GI482_19760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GI482_19765	COG0183	Belongs to the thiolase family
GI482_19775	COG4977	sequence-specific DNA binding
GI482_19785	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GI482_19790	COG1228	amidohydrolase
GI482_19795	COG0010	Belongs to the arginase family
GI482_19805	COG3583	domain protein
GI482_19805	COG3584	3D domain protein
GI482_19810	COG0788	formyltetrahydrofolate deformylase activity
GI482_19835	COG1120	ATPase activity
GI482_19845	COG2755	lipolytic protein G-D-S-L family
GI482_19855	COG0802	atpase or kinase
GI482_19860	COG1214	PFAM Peptidase M22, glycoprotease
GI482_19865	COG0456	acetyltransferase
GI482_19875	COG0488	(ABC) transporter
GI482_19885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GI482_19890	COG1266	CAAX protease self-immunity
GI482_19895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GI482_19915	COG4221	oxidoreductase activity
GI482_19955	COG2972	Histidine kinase
GI482_19960	COG4753	response regulator
GI482_19960	COG2207	Transcriptional regulator
GI482_19965	COG4213	ABC transporter substrate-binding protein
GI482_19970	COG0477	Major facilitator Superfamily
GI482_19975	COG1309	transcriptional regulator