locus-tag	class	description
KPL75_00045	COG2124	cytochrome p450
KPL75_00085	COG0463	Glycosyl transferase, family 2
KPL75_00100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KPL75_00110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_00135	COG0577	efflux transmembrane transporter activity
KPL75_00140	COG1136	(ABC) transporter
KPL75_00155	COG0488	(ABC) transporter
KPL75_00160	COG0667	Aldo Keto reductase
KPL75_00165	COG0583	DNA-binding transcription factor activity
KPL75_00180	COG2205	protein histidine kinase activity
KPL75_00185	COG0745	RESPONSE REGULATOR receiver
KPL75_00195	COG3773	Cell wall hydrolase
KPL75_00200	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KPL75_00210	COG3386	PFAM SMP-30 Gluconolaconase
KPL75_00250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_00265	COG2959	enzyme of heme biosynthesis
KPL75_00300	COG3844	kynureninase activity
KPL75_00305	COG1309	transcriptional regulator
KPL75_00330	COG3284	Transcriptional regulator
KPL75_00345	COG1349	DNA-binding transcription factor activity
KPL75_00365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPL75_00370	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPL75_00375	COG0022	dehydrogenase e1 component
KPL75_00380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KPL75_00400	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_00440	COG4176	ABC-type proline glycine betaine transport system permease component
KPL75_00445	COG4175	Glycine betaine
KPL75_00445	COG0517	IMP dehydrogenase activity
KPL75_00470	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KPL75_00475	COG2153	protein acetylation
KPL75_00480	COG3397	chitin binding
KPL75_00490	COG1819	glycosyl
KPL75_00510	COG2205	protein histidine kinase activity
KPL75_00515	COG2226	methyltransferase
KPL75_00520	COG2315	Protein conserved in bacteria
KPL75_00565	COG3973	AAA domain
KPL75_00580	COG0514	ATP-dependent DNA helicase (RecQ)
KPL75_00615	COG4637	Psort location Cytoplasmic, score
KPL75_00635	COG1227	inorganic diphosphatase activity
KPL75_00640	COG3397	chitin binding
KPL75_00645	COG2318	DinB family
KPL75_00660	COG1162	GTPase activity
KPL75_00665	COG1115	amino acid carrier protein
KPL75_00670	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_00675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KPL75_00685	COG3938	Belongs to the proline racemase family
KPL75_00690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_00745	COG1078	dGTPase activity
KPL75_00750	COG0586	Pfam SNARE associated Golgi protein
KPL75_00765	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPL75_00770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_00775	COG4166	transmembrane transport
KPL75_00785	COG4948	Mandelate Racemase Muconate Lactonizing
KPL75_00800	COG0667	Aldo Keto reductase
KPL75_00830	COG2936	dipeptidyl-peptidase activity
KPL75_00840	COG0745	RESPONSE REGULATOR receiver
KPL75_00855	COG0456	acetyltransferase
KPL75_00870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_00880	COG1164	Oligoendopeptidase f
KPL75_00885	COG0456	acetyltransferase
KPL75_00890	COG1307	EDD domain protein, DegV family
KPL75_00920	COG1181	Belongs to the D-alanine--D-alanine ligase family
KPL75_00935	COG2814	Major facilitator Superfamily
KPL75_00945	COG1664	Polymer-forming cytoskeletal
KPL75_00950	COG0789	Transcriptional regulator
KPL75_00955	COG4533	DNA binding
KPL75_00960	COG0477	Major facilitator Superfamily
KPL75_00960	COG2814	Major facilitator Superfamily
KPL75_00980	COG2261	transglycosylase associated protein
KPL75_00995	COG2226	methyltransferase
KPL75_01030	COG0436	Aminotransferase
KPL75_01035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KPL75_01060	COG1131	(ABC) transporter
KPL75_01115	COG0628	permease
KPL75_01125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPL75_01130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_01135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_01175	COG2746	aminoglycoside 3-N-acetyltransferase activity
KPL75_01200	COG0697	spore germination
KPL75_01220	COG4912	Dna alkylation repair
KPL75_01260	COG2814	Major facilitator Superfamily
KPL75_01265	COG1368	sulfuric ester hydrolase activity
KPL75_01275	COG0488	(ABC) transporter
KPL75_01280	COG1033	growth of symbiont in host cell
KPL75_01280	COG2409	Drug exporters of the RND superfamily
KPL75_01285	COG1309	transcriptional regulator
KPL75_01300	COG0287	Prephenate dehydrogenase
KPL75_01315	COG1605	Chorismate mutase
KPL75_01315	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KPL75_01345	COG1388	LysM domain
KPL75_01345	COG3584	3D domain protein
KPL75_01365	COG0277	FAD linked oxidase domain protein
KPL75_01385	COG1309	transcriptional regulator
KPL75_01395	COG1595	DNA-templated transcription, initiation
KPL75_01420	COG0579	oxidoreductase
KPL75_01425	COG1879	ABC-type sugar transport system periplasmic component
KPL75_01430	COG1172	Belongs to the binding-protein-dependent transport system permease family
KPL75_01445	COG2390	Transcriptional regulator
KPL75_01460	COG1830	Aldolase
KPL75_01465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_01490	COG0346	lactoylglutathione lyase activity
KPL75_01495	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_01515	COG1472	Belongs to the glycosyl hydrolase 3 family
KPL75_01520	COG2207	Transcriptional regulator
KPL75_01525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_01530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KPL75_01535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KPL75_01540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPL75_01545	COG3239	Fatty acid desaturase
KPL75_01560	COG3655	Transcriptional regulator
KPL75_01575	COG4377	Putative membrane peptidase family (DUF2324)
KPL75_01585	COG3279	Response regulator of the LytR AlgR family
KPL75_01605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_01610	COG0346	lactoylglutathione lyase activity
KPL75_01640	COG0714	Associated with various cellular activities
KPL75_01660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KPL75_01665	COG0753	catalase activity
KPL75_01700	COG0778	Nitroreductase
KPL75_01705	COG1846	Transcriptional regulator
KPL75_01720	COG0494	nUDIX hydrolase
KPL75_01725	COG3831	ATPase activity
KPL75_01725	COG4884	unkown
KPL75_01730	COG1136	(ABC) transporter
KPL75_01765	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_01770	COG1309	transcriptional regulator
KPL75_01810	COG0456	acetyltransferase
KPL75_01825	COG0697	spore germination
KPL75_01830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_01860	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_01860	COG0456	acetyltransferase
KPL75_01885	COG0730	response to heat
KPL75_01895	COG0833	amino acid
KPL75_01905	COG4335	DNA alkylation repair
KPL75_01930	COG0768	penicillin binding
KPL75_01940	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KPL75_01955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KPL75_01960	COG1984	allophanate hydrolase subunit 2
KPL75_01965	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KPL75_01970	COG1414	Transcriptional regulator
KPL75_01985	COG3142	Participates in the control of copper homeostasis
KPL75_01990	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_01995	COG0640	Transcriptional regulator
KPL75_02010	COG1960	acyl-CoA dehydrogenase activity
KPL75_02035	COG0640	Transcriptional regulator
KPL75_02040	COG3314	Sporulation integral membrane protein YlbJ
KPL75_02060	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
KPL75_02080	COG0574	Belongs to the PEP-utilizing enzyme family
KPL75_02080	COG3848	Pyruvate phosphate dikinase
KPL75_02090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPL75_02100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KPL75_02110	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KPL75_02115	COG0730	response to heat
KPL75_02150	COG1575	Belongs to the MenA family. Type 1 subfamily
KPL75_02165	COG0803	Belongs to the bacterial solute-binding protein 9 family
KPL75_02170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KPL75_02175	COG1121	(ABC) transporter
KPL75_02195	COG0798	PFAM Bile acid sodium symporter
KPL75_02200	COG0346	lactoylglutathione lyase activity
KPL75_02205	COG0640	Transcriptional regulator
KPL75_02210	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_02215	COG1522	sequence-specific DNA binding
KPL75_02230	COG0346	lactoylglutathione lyase activity
KPL75_02235	COG3850	Histidine kinase
KPL75_02235	COG5002	protein histidine kinase activity
KPL75_02240	COG0745	RESPONSE REGULATOR receiver
KPL75_02300	COG0384	phenazine biosynthesis protein PhzF
KPL75_02305	COG2814	Major facilitator Superfamily
KPL75_02315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KPL75_02320	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KPL75_02350	COG0789	Transcriptional regulator
KPL75_02360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KPL75_02380	COG0277	FAD linked oxidase domain protein
KPL75_02390	COG0577	efflux transmembrane transporter activity
KPL75_02405	COG3850	Histidine kinase
KPL75_02405	COG5002	protein histidine kinase activity
KPL75_02420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_02435	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_02450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KPL75_02485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPL75_02505	COG2814	Major facilitator Superfamily
KPL75_02660	COG0477	Major facilitator Superfamily
KPL75_02670	COG1846	Transcriptional regulator
KPL75_02675	COG2814	Major facilitator Superfamily
KPL75_02695	COG2814	Major facilitator Superfamily
KPL75_02700	COG1309	transcriptional regulator
KPL75_02710	COG2357	RelA SpoT domain protein
KPL75_02720	COG2197	response regulator
KPL75_02750	COG3409	Peptidoglycan-binding domain 1 protein
KPL75_02750	COG5632	N-Acetylmuramoyl-L-alanine amidase
KPL75_02805	COG0657	acetylesterase activity
KPL75_02815	COG2814	Major facilitator Superfamily
KPL75_02820	COG1309	transcriptional regulator
KPL75_02835	COG0825	malonyl-CoA metabolic process
KPL75_02845	COG2205	protein histidine kinase activity
KPL75_02850	COG0745	RESPONSE REGULATOR receiver
KPL75_02855	COG0577	efflux transmembrane transporter activity
KPL75_02860	COG1136	(ABC) transporter
KPL75_02890	COG1136	(ABC) transporter
KPL75_02930	COG2031	fatty acid transporter
KPL75_02940	COG2249	NAD(P)H dehydrogenase (quinone) activity
KPL75_02990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KPL75_02995	COG1288	antiporter activity
KPL75_03000	COG2356	endonuclease I
KPL75_03010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_03015	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KPL75_03050	COG1785	Belongs to the alkaline phosphatase family
KPL75_03055	COG0778	Nitroreductase
KPL75_03060	COG1733	regulation of RNA biosynthetic process
KPL75_03080	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_03090	COG1131	(ABC) transporter
KPL75_03120	COG1011	Hydrolase
KPL75_03130	COG2365	Tyrosine phosphatase family
KPL75_03150	COG0346	lactoylglutathione lyase activity
KPL75_03155	COG1940	carbohydrate kinase activity
KPL75_03165	COG0110	maltose O-acetyltransferase activity
KPL75_03180	COG0628	permease
KPL75_03205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KPL75_03215	COG0477	Major facilitator Superfamily
KPL75_03225	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
KPL75_03235	COG1253	flavin adenine dinucleotide binding
KPL75_03240	COG0789	Transcriptional regulator
KPL75_03245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KPL75_03270	COG0697	spore germination
KPL75_03280	COG1357	PFAM Pentapeptide repeats (8 copies)
KPL75_03285	COG3813	Protein conserved in bacteria
KPL75_03295	COG2706	6-phosphogluconolactonase activity
KPL75_03300	COG1070	Carbohydrate kinase
KPL75_03310	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KPL75_03315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KPL75_03320	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KPL75_03325	COG4702	Belongs to the UPF0303 family
KPL75_03355	COG1733	regulation of RNA biosynthetic process
KPL75_03360	COG2188	Transcriptional regulator
KPL75_03365	COG0673	inositol 2-dehydrogenase activity
KPL75_03385	COG2801	Transposase and inactivated derivatives
KPL75_03400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_03415	COG0494	nUDIX hydrolase
KPL75_03430	COG0384	phenazine biosynthesis protein PhzF
KPL75_03435	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_03445	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_03450	COG2249	NAD(P)H dehydrogenase (quinone) activity
KPL75_03455	COG1733	regulation of RNA biosynthetic process
KPL75_03470	COG1191	sigma factor activity
KPL75_03540	COG2197	response regulator
KPL75_03545	COG4585	Histidine kinase
KPL75_03575	COG0814	amino acid
KPL75_03610	COG1151	hydroxylamine reductase activity
KPL75_03650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_03660	COG2072	flavoprotein involved in K transport
KPL75_03705	COG1695	Transcriptional regulator
KPL75_03710	COG0604	alcohol dehydrogenase
KPL75_03715	COG1113	amino acid transport
KPL75_03725	COG2814	Major facilitator Superfamily
KPL75_03735	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_03740	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_03750	COG0534	Mate efflux family protein
KPL75_03755	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_03760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_03775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KPL75_03780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPL75_03795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_03800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_03805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_03810	COG3739	integral membrane protein
KPL75_03830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_03845	COG0583	DNA-binding transcription factor activity
KPL75_03870	COG1193	negative regulation of DNA recombination
KPL75_03880	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KPL75_03885	COG1164	Oligoendopeptidase f
KPL75_03910	COG3781	membrane
KPL75_03925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_03935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KPL75_03940	COG0640	Transcriptional regulator
KPL75_03945	COG0604	alcohol dehydrogenase
KPL75_03950	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KPL75_03955	COG0457	Tetratricopeptide repeat
KPL75_03960	COG2808	Putative FMN-binding domain
KPL75_03965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_03975	COG0277	FAD linked oxidase domain protein
KPL75_03995	COG1285	pathogenesis
KPL75_04005	COG2514	catechol 2,3-dioxygenase activity
KPL75_04010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_04015	COG1126	abc transporter atp-binding protein
KPL75_04020	COG0765	amino acid transport
KPL75_04025	COG2720	vancomycin resistance protein
KPL75_04050	COG1278	Cold shock
KPL75_04060	COG0716	FMN binding
KPL75_04075	COG1051	belongs to the nudix hydrolase family
KPL75_04095	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_04105	COG0165	Argininosuccinate lyase
KPL75_04120	COG4145	pantothenate transmembrane transporter activity
KPL75_04130	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_04135	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_04145	COG1657	PFAM Prenyltransferase squalene oxidase
KPL75_04150	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KPL75_04155	COG2962	Rard protein
KPL75_04160	COG3326	Membrane
KPL75_04165	COG0531	amino acid
KPL75_04195	COG2226	methyltransferase
KPL75_04200	COG4166	transmembrane transport
KPL75_04205	COG4166	transmembrane transport
KPL75_04210	COG4166	transmembrane transport
KPL75_04225	COG1595	DNA-templated transcription, initiation
KPL75_04235	COG1131	(ABC) transporter
KPL75_04255	COG0673	inositol 2-dehydrogenase activity
KPL75_04260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPL75_04265	COG0187	DNA topoisomerase II activity
KPL75_04270	COG1832	CoA-binding protein
KPL75_04275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPL75_04280	COG0745	RESPONSE REGULATOR receiver
KPL75_04290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPL75_04290	COG1328	CTP reductase activity
KPL75_04300	COG4841	protein insertion into membrane
KPL75_04305	COG0824	Thioesterase
KPL75_04340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_04360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KPL75_04390	COG2211	Major facilitator Superfamily
KPL75_04400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPL75_04415	COG0183	Belongs to the thiolase family
KPL75_04420	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_04425	COG1268	BioY protein
KPL75_04430	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_04445	COG1396	sequence-specific DNA binding
KPL75_04470	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KPL75_04490	COG0830	nickel cation binding
KPL75_04530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_04540	COG5002	protein histidine kinase activity
KPL75_04550	COG0400	carboxylic ester hydrolase activity
KPL75_04555	COG0346	lactoylglutathione lyase activity
KPL75_04560	COG0069	glutamate synthase activity
KPL75_04565	COG1902	pentaerythritol trinitrate reductase activity
KPL75_04570	COG1329	Transcriptional regulator
KPL75_04575	COG0010	Belongs to the arginase family
KPL75_04585	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KPL75_04590	COG2986	histidine ammonia-lyase
KPL75_04600	COG2226	methyltransferase
KPL75_04625	COG4846	Membrane protein involved in cytochrome C biogenesis
KPL75_04630	COG0785	Cytochrome C biogenesis protein
KPL75_04640	COG1473	amidohydrolase
KPL75_04650	COG1131	(ABC) transporter
KPL75_04660	COG0583	DNA-binding transcription factor activity
KPL75_04670	COG1346	cytolysis
KPL75_04685	COG0730	response to heat
KPL75_04710	COG1132	(ABC) transporter
KPL75_04715	COG1132	(ABC) transporter
KPL75_04720	COG3763	UPF0154 protein
KPL75_04740	COG3639	organic phosphonate transmembrane transporter activity
KPL75_04750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_04755	COG0737	Belongs to the 5'-nucleotidase family
KPL75_04765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KPL75_04770	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KPL75_04785	COG1695	Transcriptional regulator
KPL75_04790	COG1132	(ABC) transporter
KPL75_04795	COG0174	glutamine synthetase
KPL75_04800	COG0789	Transcriptional regulator
KPL75_04805	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
KPL75_04810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPL75_04815	COG2860	membrane
KPL75_04825	COG0464	growth
KPL75_04845	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KPL75_04855	COG1388	LysM domain
KPL75_04855	COG3584	3D domain protein
KPL75_04860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KPL75_04860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPL75_04860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KPL75_04865	COG1105	Belongs to the carbohydrate kinase PfkB family
KPL75_04870	COG1349	DNA-binding transcription factor activity
KPL75_04875	COG1979	alcohol dehydrogenase
KPL75_04880	COG2322	membrane
KPL75_04890	COG1113	amino acid transport
KPL75_04900	COG1473	amidohydrolase
KPL75_04905	COG1408	metallophosphoesterase
KPL75_04910	COG2116	formate transmembrane transporter activity
KPL75_04920	COG0454	-acetyltransferase
KPL75_04925	COG2217	Heavy metal translocating P-type atpase
KPL75_04935	COG1937	Protein conserved in bacteria
KPL75_04965	COG2819	hydrolase of the alpha beta superfamily
KPL75_04970	COG1120	ATPase activity
KPL75_04975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_04980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_04985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_04995	COG0708	Exodeoxyribonuclease III
KPL75_05000	COG2169	Transcriptional regulator
KPL75_05005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPL75_05010	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KPL75_05015	COG2195	Cleaves the N-terminal amino acid of tripeptides
KPL75_05020	COG2364	Membrane
KPL75_05040	COG0346	lactoylglutathione lyase activity
KPL75_05045	COG5001	Diguanylate cyclase
KPL75_05045	COG3300	MHYT domain
KPL75_05080	COG1346	cytolysis
KPL75_05090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_05095	COG2945	thiolester hydrolase activity
KPL75_05095	COG0596	Alpha beta hydrolase
KPL75_05100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KPL75_05110	COG2188	Transcriptional regulator
KPL75_05115	COG2723	6-phospho-beta-galactosidase activity
KPL75_05125	COG3773	Cell wall hydrolase
KPL75_05135	COG1368	sulfuric ester hydrolase activity
KPL75_05150	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KPL75_05155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KPL75_05170	COG4550	Control of competence regulator ComK, YlbF/YmcA
KPL75_05175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KPL75_05180	COG1013	pyruvate-flavodoxin oxidoreductase activity
KPL75_05185	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KPL75_05185	COG0674	pyruvate-flavodoxin oxidoreductase activity
KPL75_05195	COG2359	stage V sporulation protein S
KPL75_05200	COG1692	metallophosphoesterase
KPL75_05205	COG1418	mRNA catabolic process
KPL75_05210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KPL75_05215	COG1058	Belongs to the CinA family
KPL75_05215	COG1546	Belongs to the CinA family
KPL75_05220	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KPL75_05225	COG1426	Protein conserved in bacteria
KPL75_05240	COG0300	oxidoreductase activity
KPL75_05245	COG0612	Peptidase, M16
KPL75_05250	COG0612	Peptidase, M16
KPL75_05255	COG1079	Belongs to the binding-protein-dependent transport system permease family
KPL75_05260	COG4603	Belongs to the binding-protein-dependent transport system permease family
KPL75_05265	COG3845	ABC transporter
KPL75_05270	COG1744	ABC transporter substrate-binding protein PnrA-like
KPL75_05275	COG2188	Transcriptional regulator
KPL75_05285	COG1674	ftsk spoiiie
KPL75_05295	COG0740	serine-type endopeptidase activity
KPL75_05300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPL75_05310	COG0527	aspartate kinase activity
KPL75_05315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPL75_05320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPL75_05455	COG0582	viral genome integration into host DNA
KPL75_05490	COG0305	Participates in initiation and elongation during chromosome replication
KPL75_05535	COG1396	sequence-specific DNA binding
KPL75_05550	COG2856	Zn peptidase
KPL75_05565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPL75_05570	COG1873	PFAM PRC-barrel domain
KPL75_05575	COG0612	Peptidase, M16
KPL75_05580	COG0726	polysaccharide deacetylase
KPL75_05585	COG1185	polyribonucleotide nucleotidyltransferase activity
KPL75_05595	COG0196	riboflavin kinase activity
KPL75_05605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KPL75_05610	COG1550	Protein conserved in bacteria
KPL75_05615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KPL75_05620	COG1358	cellular component organization or biogenesis
KPL75_05625	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KPL75_05630	COG0195	Participates in both transcription termination and antitermination
KPL75_05635	COG0779	Required for maturation of 30S ribosomal subunits
KPL75_05645	COG0442	prolyl-tRNA aminoacylation
KPL75_05650	COG0750	zinc metalloprotease
KPL75_05660	COG4589	Belongs to the CDS family
KPL75_05670	COG0233	cytoplasmic translational termination
KPL75_05675	COG0528	UMP kinase activity
KPL75_05680	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KPL75_05690	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KPL75_05695	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KPL75_05700	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KPL75_05705	COG4974	Belongs to the 'phage' integrase family
KPL75_05710	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KPL75_05715	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPL75_05720	COG0758	DNA mediated transformation
KPL75_05725	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KPL75_05730	COG0045	succinate-CoA ligase (ADP-forming) activity
KPL75_05735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPL75_05750	COG0335	large ribosomal subunit rRNA binding
KPL75_05755	COG0336	Belongs to the RNA methyltransferase TrmD family
KPL75_05760	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KPL75_05765	COG1837	Belongs to the UPF0109 family
KPL75_05775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KPL75_05785	COG0552	protein localization to endoplasmic reticulum
KPL75_05790	COG1196	nuclear chromosome segregation
KPL75_05795	COG0571	ribonuclease III activity
KPL75_05800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPL75_05805	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_05810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KPL75_05825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KPL75_05830	COG1461	Dihydroxyacetone kinase
KPL75_05835	COG1302	Protein conserved in bacteria
KPL75_05850	COG1564	THIamine pyrophosphokinase
KPL75_05855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KPL75_05865	COG0515	serine threonine protein kinase
KPL75_05865	COG2815	serine threonine protein kinase
KPL75_05870	COG0631	protein serine/threonine phosphatase activity
KPL75_05875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KPL75_05880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KPL75_05880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPL75_05885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPL75_05890	COG0242	peptide deformylase activity
KPL75_05895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KPL75_05900	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KPL75_05905	COG1758	RNA polymerase activity
KPL75_05920	COG1561	YicC-like family, N-terminal region
KPL75_05925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KPL75_05940	COG0006	proline dipeptidase activity
KPL75_05960	COG3069	C4-dicarboxylate transmembrane transporter activity
KPL75_05960	COG3069	C4-dicarboxylate transmembrane transporter activity
KPL75_06020	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KPL75_06025	COG0564	pseudouridine synthase activity
KPL75_06045	COG3599	regulation of cell shape
KPL75_06050	COG2302	S4 RNA-binding domain
KPL75_06055	COG0762	integral membrane protein
KPL75_06060	COG1799	cell septum assembly
KPL75_06065	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KPL75_06075	COG1873	PFAM PRC-barrel domain
KPL75_06080	COG1191	sigma factor activity
KPL75_06085	COG1191	sigma factor activity
KPL75_06095	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KPL75_06100	COG0849	cell division
KPL75_06105	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KPL75_06120	COG0772	Belongs to the SEDS family
KPL75_06125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KPL75_06130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPL75_06135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KPL75_06140	COG0768	penicillin binding
KPL75_06145	COG0768	penicillin binding
KPL75_06155	COG0275	rRNA processing
KPL75_06160	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KPL75_06165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPL75_06170	COG0454	-acetyltransferase
KPL75_06180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KPL75_06185	COG1399	metal-binding, possibly nucleic acid-binding protein
KPL75_06190	COG1323	Belongs to the UPF0348 family
KPL75_06195	COG3480	Lon protease (S16) C-terminal proteolytic domain
KPL75_06200	COG1752	Esterase of the alpha-beta hydrolase superfamily
KPL75_06205	COG3314	Sporulation integral membrane protein YlbJ
KPL75_06215	COG0742	ribosomal rna small subunit methyltransferase
KPL75_06225	COG4471	UPF0298 protein
KPL75_06230	COG3679	Belongs to the UPF0342 family
KPL75_06235	COG0406	alpha-ribazole phosphatase activity
KPL75_06250	COG2340	Cysteine-rich secretory protein family
KPL75_06265	COG3336	cytochrome c oxidase
KPL75_06290	COG0109	protoheme IX farnesyltransferase activity
KPL75_06295	COG1612	heme a metabolic process
KPL75_06300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KPL75_06305	COG0772	Belongs to the SEDS family
KPL75_06310	COG4838	Belongs to the UPF0358 family
KPL75_06315	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KPL75_06320	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KPL75_06330	COG4896	Protein conserved in bacteria
KPL75_06345	COG1217	gtp-binding protein TYPA
KPL75_06355	COG0483	inositol monophosphate 1-phosphatase activity
KPL75_06365	COG4493	Belongs to the UPF0637 family
KPL75_06370	COG4476	Belongs to the UPF0223 family
KPL75_06375	COG1982	Orn Lys Arg decarboxylase major
KPL75_06425	COG0022	dehydrogenase e1 component
KPL75_06430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KPL75_06445	COG0561	phosphatase activity
KPL75_06450	COG5503	Protein of unknown function (DUF1447)
KPL75_06455	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KPL75_06460	COG0569	domain protein
KPL75_06470	COG1473	amidohydrolase
KPL75_06475	COG2171	N-acyltransferase activity
KPL75_06480	COG0583	DNA-binding transcription factor activity
KPL75_06485	COG0517	IMP dehydrogenase activity
KPL75_06495	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
KPL75_06505	COG4703	Protein of unknown function (DUF1797)
KPL75_06520	COG2200	EAL domain
KPL75_06525	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_06530	COG1408	metallophosphoesterase
KPL75_06575	COG2814	Major facilitator Superfamily
KPL75_06585	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KPL75_06595	COG3209	COG3209 Rhs family protein
KPL75_06605	COG2205	protein histidine kinase activity
KPL75_06615	COG0436	Aminotransferase
KPL75_06620	COG1609	Transcriptional regulator
KPL75_06625	COG3833	ABC-type maltose transport systems, permease component
KPL75_06630	COG1175	transmembrane transport
KPL75_06635	COG2182	Extracellular solute-binding protein
KPL75_06645	COG0366	Alpha amylase catalytic
KPL75_06650	COG3842	ATPase activity
KPL75_06690	COG0183	Belongs to the thiolase family
KPL75_06720	COG1695	Transcriptional regulator
KPL75_06725	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_06735	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KPL75_06740	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KPL75_06745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KPL75_06750	COG0436	Aminotransferase
KPL75_06760	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KPL75_06765	COG0235	Class ii aldolase
KPL75_06770	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KPL75_06785	COG2084	Dehydrogenase
KPL75_06795	COG2199	diguanylate cyclase activity
KPL75_06800	COG0778	Nitroreductase
KPL75_06825	COG1263	PTS System
KPL75_06825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_06825	COG2190	(PTS) system
KPL75_06830	COG3711	transcriptional antiterminator
KPL75_06840	COG2188	Transcriptional regulator
KPL75_06845	COG0363	glucosamine-6-phosphate deaminase activity
KPL75_06860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KPL75_06865	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KPL75_06875	COG1547	Domain of unknown function (DUF309)
KPL75_06885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KPL75_06890	COG4086	secreted protein
KPL75_06895	COG0561	phosphatase activity
KPL75_06900	COG0697	spore germination
KPL75_06915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPL75_06955	COG1686	Belongs to the peptidase S11 family
KPL75_06960	COG1725	Transcriptional regulator
KPL75_06965	COG1131	(ABC) transporter
KPL75_06990	COG1846	Transcriptional regulator
KPL75_07005	COG0598	Magnesium transport protein CorA
KPL75_07030	COG4974	Belongs to the 'phage' integrase family
KPL75_07040	COG0735	belongs to the Fur family
KPL75_07045	COG1300	Membrane
KPL75_07065	COG0667	Aldo Keto reductase
KPL75_07070	COG0656	L-ascorbic acid biosynthetic process
KPL75_07075	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_07075	COG0456	acetyltransferase
KPL75_07085	COG0737	Belongs to the 5'-nucleotidase family
KPL75_07085	COG1525	nuclease
KPL75_07085	COG4085	toxin activity
KPL75_07100	COG0596	Alpha beta hydrolase
KPL75_07105	COG2056	Na+-H+ antiporter family
KPL75_07110	COG1609	Transcriptional regulator
KPL75_07115	COG0456	acetyltransferase
KPL75_07120	COG1073	alpha beta
KPL75_07135	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPL75_07135	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KPL75_07140	COG0307	riboflavin synthase, alpha
KPL75_07145	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KPL75_07145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KPL75_07160	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KPL75_07170	COG1073	alpha beta
KPL75_07170	COG2226	methyltransferase
KPL75_07175	COG0156	8-amino-7-oxononanoate synthase activity
KPL75_07185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_07195	COG1757	Na H antiporter
KPL75_07200	COG0737	Belongs to the 5'-nucleotidase family
KPL75_07210	COG1522	sequence-specific DNA binding
KPL75_07230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KPL75_07255	COG0300	oxidoreductase activity
KPL75_07260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_07265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPL75_07270	COG1760	l-serine dehydratase
KPL75_07275	COG1760	l-serine dehydratase
KPL75_07290	COG1234	tRNA 3'-trailer cleavage
KPL75_07305	COG1285	pathogenesis
KPL75_07325	COG2195	Cleaves the N-terminal amino acid of tripeptides
KPL75_07330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_07345	COG1376	ErfK ybiS ycfS ynhG family protein
KPL75_07350	COG4129	membrane
KPL75_07355	COG1126	abc transporter atp-binding protein
KPL75_07360	COG0765	amino acid transport
KPL75_07365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_07380	COG2816	NAD+ diphosphatase activity
KPL75_07385	COG2323	membrane
KPL75_07390	COG0772	Belongs to the SEDS family
KPL75_07395	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPL75_07400	COG0022	dehydrogenase e1 component
KPL75_07405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KPL75_07410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KPL75_07415	COG3426	butyrate kinase activity
KPL75_07425	COG0280	phosphate acetyltransferase
KPL75_07430	COG3290	protein histidine kinase activity
KPL75_07430	COG3829	transcription factor binding
KPL75_07440	COG0584	glycerophosphoryl diester phosphodiesterase
KPL75_07445	COG3093	addiction module antidote protein HigA
KPL75_07550	COG0745	RESPONSE REGULATOR receiver
KPL75_07555	COG0750	zinc metalloprotease
KPL75_07560	COG0497	DNA recombination
KPL75_07565	COG1438	arginine binding
KPL75_07570	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KPL75_07575	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KPL75_07580	COG0142	geranyltranstransferase activity
KPL75_07585	COG1722	exodeoxyribonuclease VII activity
KPL75_07590	COG1570	exodeoxyribonuclease VII activity
KPL75_07595	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KPL75_07600	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KPL75_07605	COG1302	Protein conserved in bacteria
KPL75_07610	COG0439	Biotin carboxylase
KPL75_07615	COG0511	ligase activity, forming carbon-carbon bonds
KPL75_07660	COG3854	ATPases associated with a variety of cellular activities
KPL75_07680	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KPL75_07685	COG0006	proline dipeptidase activity
KPL75_07700	COG3872	metal-dependent enzyme
KPL75_07710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KPL75_07745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_07755	COG1609	Transcriptional regulator
KPL75_07765	COG2076	Multidrug Resistance protein
KPL75_07770	COG2076	Multidrug Resistance protein
KPL75_07810	COG1725	Transcriptional regulator
KPL75_07825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KPL75_07830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KPL75_07835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KPL75_07840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KPL75_07855	COG2801	Transposase and inactivated derivatives
KPL75_07880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KPL75_07905	COG4970	Tfp pilus assembly protein FimT
KPL75_07915	COG1459	type II secretion system
KPL75_07920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KPL75_07975	COG1410	methionine synthase
KPL75_07975	COG0646	methionine synthase
KPL75_07980	COG0646	methionine synthase
KPL75_07980	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KPL75_07985	COG0626	cystathionine gamma-synthase activity
KPL75_07990	COG0626	cystathionine gamma-synthase activity
KPL75_08010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_08020	COG1940	carbohydrate kinase activity
KPL75_08025	COG4483	Protein conserved in bacteria
KPL75_08030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KPL75_08035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KPL75_08040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KPL75_08045	COG0704	Plays a role in the regulation of phosphate uptake
KPL75_08055	COG0581	inorganic phosphate transmembrane transporter activity
KPL75_08060	COG0573	inorganic phosphate transmembrane transporter activity
KPL75_08065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KPL75_08070	COG0768	penicillin binding
KPL75_08075	COG0477	Major facilitator Superfamily
KPL75_08080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KPL75_08100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KPL75_08105	COG0735	belongs to the Fur family
KPL75_08110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KPL75_08115	COG1121	(ABC) transporter
KPL75_08120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_08130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KPL75_08150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KPL75_08155	COG2384	SAM-dependent methyltransferase
KPL75_08160	COG2010	Cytochrome c
KPL75_08165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KPL75_08170	COG0358	DNA primase activity
KPL75_08180	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KPL75_08185	COG0517	IMP dehydrogenase activity
KPL75_08190	COG1381	Involved in DNA repair and RecF pathway recombination
KPL75_08200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KPL75_08205	COG0295	cytidine deaminase activity
KPL75_08210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KPL75_08215	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KPL75_08220	COG1480	7TM receptor with intracellular HD hydrolase
KPL75_08225	COG1702	phosphate starvation-inducible protein PhoH
KPL75_08240	COG1610	YqeY-like protein
KPL75_08245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KPL75_08250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KPL75_08255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KPL75_08265	COG0484	heat shock protein binding
KPL75_08270	COG0443	Heat shock 70 kDa protein
KPL75_08280	COG1420	regulation of RNA biosynthetic process
KPL75_08290	COG1733	regulation of RNA biosynthetic process
KPL75_08295	COG0481	GTPase activity
KPL75_08305	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KPL75_08310	COG0268	Binds directly to 16S ribosomal RNA
KPL75_08315	COG1466	dna polymerase III delta subunit
KPL75_08325	COG0658	competence protein
KPL75_08325	COG2333	competence protein COMEC
KPL75_08330	COG2131	deaminase
KPL75_08335	COG1555	photosystem II stabilization
KPL75_08335	COG1596	polysaccharide export
KPL75_08340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KPL75_08345	COG2226	methyltransferase
KPL75_08350	COG0799	negative regulation of ribosome biogenesis
KPL75_08355	COG1713	HD superfamily hydrolase involved in NAD metabolism
KPL75_08360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KPL75_08365	COG1534	Rna-binding protein
KPL75_08370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KPL75_08375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KPL75_08380	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KPL75_08390	COG0688	phosphatidylethanolamine metabolic process
KPL75_08410	COG2357	RelA SpoT domain protein
KPL75_08420	COG1785	Belongs to the alkaline phosphatase family
KPL75_08430	COG2267	carboxylic ester hydrolase activity
KPL75_08470	COG3186	Phenylalanine-4-hydroxylase
KPL75_08475	COG2154	pterin-4-alpha-carbinolamine dehydratase
KPL75_08480	COG2801	Transposase and inactivated derivatives
KPL75_08490	COG2514	catechol 2,3-dioxygenase activity
KPL75_08495	COG2259	Doxx family
KPL75_08535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KPL75_08545	COG1454	alcohol dehydrogenase
KPL75_08545	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_08550	COG0626	cystathionine gamma-synthase activity
KPL75_08555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KPL75_08560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_08565	COG2226	methyltransferase
KPL75_08580	COG0768	penicillin binding
KPL75_08590	COG0572	uridine kinase
KPL75_08595	COG0826	peptidase U32
KPL75_08600	COG0826	peptidase U32
KPL75_08605	COG4122	O-methyltransferase activity
KPL75_08610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KPL75_08620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KPL75_08630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KPL75_08640	COG0628	permease
KPL75_08660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KPL75_08670	COG0482	sulfurtransferase activity
KPL75_08675	COG1104	cysteine desulfurase activity
KPL75_08680	COG1959	2 iron, 2 sulfur cluster binding
KPL75_08685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KPL75_08695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KPL75_08730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KPL75_08735	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPL75_08740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KPL75_08740	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KPL75_08745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPL75_08750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KPL75_08750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KPL75_08760	COG2244	polysaccharide biosynthetic process
KPL75_08765	COG2323	membrane
KPL75_08775	COG1862	Preprotein translocase
KPL75_08795	COG2255	four-way junction helicase activity
KPL75_08800	COG0632	four-way junction helicase activity
KPL75_08805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KPL75_08815	COG0697	spore germination
KPL75_08820	COG0640	Transcriptional regulator
KPL75_08825	COG2801	Transposase and inactivated derivatives
KPL75_08850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KPL75_08855	COG0157	Belongs to the NadC ModD family
KPL75_08860	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KPL75_08865	COG1104	cysteine desulfurase activity
KPL75_08870	COG1827	regulation of RNA biosynthetic process
KPL75_08875	COG2258	MOSC domain
KPL75_08880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_08885	COG0077	Prephenate dehydratase
KPL75_08890	COG0577	efflux transmembrane transporter activity
KPL75_08895	COG0577	efflux transmembrane transporter activity
KPL75_08900	COG1136	(ABC) transporter
KPL75_08905	COG5002	protein histidine kinase activity
KPL75_08910	COG0745	RESPONSE REGULATOR receiver
KPL75_08915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KPL75_08920	COG3290	protein histidine kinase activity
KPL75_08930	COG2868	ribosomal protein
KPL75_08940	COG1530	ribonuclease E activity
KPL75_08945	COG1994	Peptidase M50
KPL75_08950	COG0739	heme binding
KPL75_08955	COG2894	cell division
KPL75_08960	COG0850	regulation of cytokinetic process
KPL75_08975	COG1077	Cell shape determining protein MreB Mrl
KPL75_08980	COG2003	Belongs to the UPF0758 family
KPL75_08985	COG0424	maF-like protein
KPL75_08995	COG0285	dihydrofolate synthase activity
KPL75_09010	COG1388	LysM domain
KPL75_09015	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KPL75_09020	COG0113	porphobilinogen synthase activity
KPL75_09025	COG1587	Uroporphyrinogen-III synthase
KPL75_09030	COG0181	hydroxymethylbilane synthase activity
KPL75_09035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KPL75_09040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KPL75_09045	COG1846	Transcriptional regulator
KPL75_09050	COG1764	response to oxidative stress
KPL75_09055	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KPL75_09065	COG0470	DNA polymerase III
KPL75_09065	COG1067	ATP-dependent peptidase activity
KPL75_09075	COG0544	peptidyl-prolyl cis-trans isomerase activity
KPL75_09105	COG0622	Phosphoesterase
KPL75_09115	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KPL75_09120	COG5401	PFAM Sporulation and spore germination
KPL75_09130	COG2197	response regulator
KPL75_09135	COG2233	PERMEase
KPL75_09140	COG0402	S-adenosylhomocysteine deaminase activity
KPL75_09145	COG1983	PspC domain protein
KPL75_09150	COG1396	sequence-specific DNA binding
KPL75_09155	COG0697	spore germination
KPL75_09165	COG1959	2 iron, 2 sulfur cluster binding
KPL75_09170	COG1668	transmembrane transport
KPL75_09175	COG4152	abc transporter atp-binding protein
KPL75_09180	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
KPL75_09185	COG1360	Flagellar Motor Protein
KPL75_09190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KPL75_09195	COG1876	peptidase activity
KPL75_09200	COG0824	Thioesterase
KPL75_09205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KPL75_09210	COG1053	succinate dehydrogenase
KPL75_09215	COG2009	succinate dehydrogenase
KPL75_09220	COG1719	4-vinyl reductase, 4VR
KPL75_09225	COG0322	excinuclease ABC activity
KPL75_09230	COG3118	belongs to the thioredoxin family
KPL75_09235	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KPL75_09240	COG2086	electron transfer activity
KPL75_09245	COG1024	Enoyl-CoA hydratase
KPL75_09250	COG1309	transcriptional regulator
KPL75_09255	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_09265	COG2318	DinB family
KPL75_09295	COG1131	(ABC) transporter
KPL75_09300	COG2205	protein histidine kinase activity
KPL75_09305	COG0745	RESPONSE REGULATOR receiver
KPL75_09315	COG4895	conserved protein (DUF2196)
KPL75_09320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KPL75_09330	COG4509	Sortase family
KPL75_09335	COG1120	ATPase activity
KPL75_09350	COG5386	Cell surface protein
KPL75_09360	COG5386	Cell surface protein
KPL75_09365	COG1114	Component of the transport system for branched-chain amino acids
KPL75_09375	COG1193	negative regulation of DNA recombination
KPL75_09380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KPL75_09380	COG1796	DNA polymerase
KPL75_09385	COG1286	toxin biosynthetic process
KPL75_09390	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KPL75_09395	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KPL75_09415	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_09430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KPL75_09435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPL75_09445	COG1418	mRNA catabolic process
KPL75_09465	COG2814	Major facilitator Superfamily
KPL75_09470	COG1566	PFAM secretion protein HlyD family protein
KPL75_09475	COG1309	transcriptional regulator
KPL75_09480	COG1363	Peptidase, m42
KPL75_09490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KPL75_09505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPL75_09515	COG1484	DNA-dependent DNA replication
KPL75_09520	COG3611	Membrane attachment protein
KPL75_09525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KPL75_09530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KPL75_09535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KPL75_09545	COG1971	Probably functions as a manganese efflux pump
KPL75_09555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPL75_09555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPL75_09560	COG5002	protein histidine kinase activity
KPL75_09565	COG0745	RESPONSE REGULATOR receiver
KPL75_09585	COG0538	isocitrate dehydrogenase activity
KPL75_09590	COG0372	Belongs to the citrate synthase family
KPL75_09600	COG0628	permease
KPL75_09605	COG3030	protein affecting phage T7 exclusion by the F plasmid
KPL75_09615	COG0205	6-phosphofructokinase activity
KPL75_09625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KPL75_09630	COG1725	Transcriptional regulator
KPL75_09635	COG0281	malic enzyme
KPL75_09640	COG0587	DNA-directed DNA polymerase activity
KPL75_09655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KPL75_09670	COG4109	DRTGG domain
KPL75_09685	COG0006	proline dipeptidase activity
KPL75_09725	COG0662	Cupin 2, conserved barrel domain protein
KPL75_09740	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_09745	COG0589	response to stress
KPL75_09765	COG0165	Argininosuccinate lyase
KPL75_09770	COG0137	argininosuccinate synthase activity
KPL75_09785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_09805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KPL75_09810	COG0827	DNA restriction-modification system
KPL75_09815	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KPL75_09820	COG3874	Sporulation protein YtfJ
KPL75_09835	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KPL75_09845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KPL75_09860	COG1104	cysteine desulfurase activity
KPL75_09865	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KPL75_09870	COG0583	DNA-binding transcription factor activity
KPL75_09875	COG0697	spore germination
KPL75_09880	COG1309	transcriptional regulator
KPL75_09885	COG1956	GAF domain-containing protein
KPL75_09890	COG0626	cystathionine gamma-synthase activity
KPL75_09895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KPL75_09920	COG1595	DNA-templated transcription, initiation
KPL75_09930	COG0110	maltose O-acetyltransferase activity
KPL75_09940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KPL75_09945	COG0454	-acetyltransferase
KPL75_09950	COG0517	IMP dehydrogenase activity
KPL75_09955	COG0123	including yeast histone deacetylase and acetoin utilization protein
KPL75_09960	COG2267	carboxylic ester hydrolase activity
KPL75_09975	COG0673	inositol 2-dehydrogenase activity
KPL75_09980	COG1970	mechanosensitive ion channel activity
KPL75_10000	COG1609	Transcriptional regulator
KPL75_10005	COG4851	CamS sex pheromone cAM373 precursor
KPL75_10010	COG3118	belongs to the thioredoxin family
KPL75_10020	COG2309	aminopeptidase activity
KPL75_10045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_10050	COG0697	spore germination
KPL75_10055	COG0789	Transcriptional regulator
KPL75_10060	COG1695	Transcriptional regulator
KPL75_10070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KPL75_10080	COG1674	ftsk spoiiie
KPL75_10095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPL75_10100	COG4848	Belongs to the UPF0354 family
KPL75_10105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_10110	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KPL75_10115	COG1363	Peptidase, m42
KPL75_10125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_10130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KPL75_10140	COG0510	thiamine kinase activity
KPL75_10145	COG1523	belongs to the glycosyl hydrolase 13 family
KPL75_10155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KPL75_10160	COG1349	DNA-binding transcription factor activity
KPL75_10165	COG1187	pseudouridine synthase activity
KPL75_10170	COG2244	polysaccharide biosynthetic process
KPL75_10175	COG2081	HI0933 family
KPL75_10180	COG2814	Major facilitator Superfamily
KPL75_10190	COG3832	glyoxalase III activity
KPL75_10210	COG1329	Transcriptional regulator
KPL75_10235	COG0314	molybdopterin synthase activity
KPL75_10240	COG1763	Mo-molybdopterin cofactor biosynthetic process
KPL75_10245	COG0303	'Molybdopterin
KPL75_10250	COG0315	cyclic pyranopterin monophosphate synthase activity
KPL75_10255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_10260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KPL75_10280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_10290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KPL75_10335	COG2814	Major facilitator Superfamily
KPL75_10340	COG0475	glutathione-regulated potassium exporter activity
KPL75_10345	COG0490	domain, Protein
KPL75_10350	COG0582	viral genome integration into host DNA
KPL75_10365	COG1136	(ABC) transporter
KPL75_10385	COG1242	4 iron, 4 sulfur cluster binding
KPL75_10390	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KPL75_10395	COG1794	racemase activity, acting on amino acids and derivatives
KPL75_10410	COG2267	carboxylic ester hydrolase activity
KPL75_10415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KPL75_10420	COG0671	phosphoesterase, PA-phosphatase related
KPL75_10425	COG0438	transferase activity, transferring glycosyl groups
KPL75_10450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KPL75_10455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KPL75_10495	COG5002	protein histidine kinase activity
KPL75_10500	COG3852	Histidine kinase
KPL75_10505	COG0753	catalase activity
KPL75_10510	COG2267	carboxylic ester hydrolase activity
KPL75_10520	COG1368	sulfuric ester hydrolase activity
KPL75_10530	COG4895	conserved protein (DUF2196)
KPL75_10550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_10555	COG1116	anion transmembrane transporter activity
KPL75_10560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_10580	COG0494	nUDIX hydrolase
KPL75_10615	COG1854	S-ribosylhomocysteine lyase activity
KPL75_10625	COG0288	reversible hydration of carbon dioxide
KPL75_10630	COG1271	oxidase subunit
KPL75_10635	COG1294	oxidase, subunit
KPL75_10655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_10680	COG1842	Phage shock protein A
KPL75_10705	COG3859	Proton-coupled thiamine transporter YuaJ
KPL75_10710	COG5002	protein histidine kinase activity
KPL75_10715	COG0745	RESPONSE REGULATOR receiver
KPL75_10740	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KPL75_10745	COG1597	lipid kinase activity
KPL75_10760	COG1136	(ABC) transporter
KPL75_10775	COG5002	protein histidine kinase activity
KPL75_10785	COG0586	Pfam SNARE associated Golgi protein
KPL75_10795	COG0577	efflux transmembrane transporter activity
KPL75_10800	COG1136	(ABC) transporter
KPL75_10805	COG2207	Transcriptional regulator
KPL75_10805	COG3708	Transcriptional regulator
KPL75_10815	COG1131	(ABC) transporter
KPL75_10825	COG5658	integral membrane protein
KPL75_10830	COG0640	Transcriptional regulator
KPL75_10835	COG0745	RESPONSE REGULATOR receiver
KPL75_10840	COG2205	protein histidine kinase activity
KPL75_10845	COG0577	efflux transmembrane transporter activity
KPL75_10850	COG0577	efflux transmembrane transporter activity
KPL75_10855	COG1136	(ABC) transporter
KPL75_10860	COG0577	efflux transmembrane transporter activity
KPL75_10875	COG2188	Transcriptional regulator
KPL75_10895	COG3964	amidohydrolase
KPL75_10910	COG0745	RESPONSE REGULATOR receiver
KPL75_10915	COG4948	Mandelate Racemase Muconate Lactonizing
KPL75_10925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KPL75_10930	COG0596	Alpha beta hydrolase
KPL75_10935	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KPL75_10940	COG1169	isochorismate synthase
KPL75_10945	COG1575	Belongs to the MenA family. Type 1 subfamily
KPL75_10950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KPL75_10955	COG1278	Cold shock
KPL75_10980	COG0058	SHG alpha-glucan phosphorylase activity
KPL75_10990	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPL75_10995	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KPL75_11000	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KPL75_11015	COG1309	transcriptional regulator
KPL75_11155	COG1285	pathogenesis
KPL75_11160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KPL75_11170	COG0166	Belongs to the GPI family
KPL75_11175	COG2155	Conserved Protein
KPL75_11180	COG1098	S1 RNA binding domain
KPL75_11185	COG0436	Aminotransferase
KPL75_11190	COG1522	sequence-specific DNA binding
KPL75_11195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KPL75_11200	COG2267	carboxylic ester hydrolase activity
KPL75_11210	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KPL75_11230	COG5018	Exonuclease
KPL75_11235	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPL75_11255	COG2050	protein possibly involved in aromatic compounds catabolism
KPL75_11265	COG1268	BioY protein
KPL75_11275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KPL75_11280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KPL75_11290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KPL75_11295	COG3584	3D domain protein
KPL75_11320	COG1252	NADH dehydrogenase
KPL75_11325	COG0492	ferredoxin-NADP+ reductase activity
KPL75_11330	COG3708	Transcriptional regulator
KPL75_11345	COG1683	Conserved Protein
KPL75_11355	COG0316	Belongs to the HesB IscA family
KPL75_11360	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KPL75_11365	COG4844	belongs to the
KPL75_11370	COG1252	NADH dehydrogenase
KPL75_11380	COG2274	protein secretion by the type I secretion system
KPL75_11385	COG0390	transport system, permease component
KPL75_11390	COG2824	Alkylphosphonate utilization operon protein PhnA
KPL75_11440	COG4837	Protein of unknown function (DUF1462)
KPL75_11445	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KPL75_11455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KPL75_11460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KPL75_11480	COG1358	cellular component organization or biogenesis
KPL75_11495	COG0647	UMP catabolic process
KPL75_11505	COG2445	Protein of unknown function DUF86
KPL75_11510	COG1494	fructose-1,6-bisphosphatase
KPL75_11530	COG4470	Protein conserved in bacteria
KPL75_11540	COG0789	Transcriptional regulator
KPL75_11545	COG4377	Putative membrane peptidase family (DUF2324)
KPL75_11570	COG0739	heme binding
KPL75_11580	COG3377	Domain of unknown function (DUF1805)
KPL75_11585	COG0737	Belongs to the 5'-nucleotidase family
KPL75_11590	COG0719	Fe-S assembly protein
KPL75_11595	COG0822	iron-sulfur transferase activity
KPL75_11600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KPL75_11605	COG0719	Fe-S assembly protein
KPL75_11610	COG0396	ATPase activity
KPL75_11615	COG1464	Belongs to the NlpA lipoprotein family
KPL75_11620	COG1464	Belongs to the NlpA lipoprotein family
KPL75_11625	COG2011	ABC-type metal ion transport system permease component
KPL75_11640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_11645	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPL75_11650	COG0509	glycine decarboxylation via glycine cleavage system
KPL75_11655	COG1393	Belongs to the ArsC family
KPL75_11700	COG1309	transcriptional regulator
KPL75_11705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_11710	COG1960	acyl-CoA dehydrogenase activity
KPL75_11715	COG0183	Belongs to the thiolase family
KPL75_11720	COG1024	Enoyl-CoA hydratase
KPL75_11720	COG1250	3-hydroxyacyl-CoA dehydrogenase
KPL75_11730	COG1686	Belongs to the peptidase S11 family
KPL75_11735	COG0506	proline dehydrogenase activity
KPL75_11745	COG0011	TIGRFAM Protein of
KPL75_11750	COG0840	transmembrane signaling receptor activity
KPL75_11770	COG2801	Transposase and inactivated derivatives
KPL75_11775	COG2814	Major facilitator Superfamily
KPL75_11780	COG0531	amino acid
KPL75_11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_11810	COG5002	protein histidine kinase activity
KPL75_11815	COG0745	RESPONSE REGULATOR receiver
KPL75_11830	COG1131	(ABC) transporter
KPL75_11855	COG0586	Pfam SNARE associated Golgi protein
KPL75_11865	COG1376	ErfK ybiS ycfS ynhG family protein
KPL75_11870	COG0745	RESPONSE REGULATOR receiver
KPL75_11875	COG5002	protein histidine kinase activity
KPL75_11890	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPL75_11900	COG0840	transmembrane signaling receptor activity
KPL75_11910	COG2151	metal-sulfur cluster biosynthetic enzyme
KPL75_11915	COG3227	Zinc metalloprotease (Elastase)
KPL75_11935	COG0586	Pfam SNARE associated Golgi protein
KPL75_11940	COG0475	glutathione-regulated potassium exporter activity
KPL75_11945	COG0490	domain, Protein
KPL75_11950	COG1115	amino acid carrier protein
KPL75_11955	COG0783	Belongs to the Dps family
KPL75_11975	COG1611	Belongs to the LOG family
KPL75_11985	COG1528	Iron-storage protein
KPL75_11995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_12000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_12005	COG1115	amino acid carrier protein
KPL75_12010	COG1115	amino acid carrier protein
KPL75_12015	COG2910	NAD(P)H-binding
KPL75_12035	COG0656	L-ascorbic acid biosynthetic process
KPL75_12040	COG2814	Major facilitator Superfamily
KPL75_12045	COG1733	regulation of RNA biosynthetic process
KPL75_12055	COG1252	NADH dehydrogenase
KPL75_12060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KPL75_12075	COG0840	transmembrane signaling receptor activity
KPL75_12075	COG3290	protein histidine kinase activity
KPL75_12115	COG0488	(ABC) transporter
KPL75_12120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_12145	COG1522	sequence-specific DNA binding
KPL75_12150	COG0288	reversible hydration of carbon dioxide
KPL75_12155	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
KPL75_12160	COG2233	PERMEase
KPL75_12210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KPL75_12215	COG0557	exoribonuclease II activity
KPL75_12220	COG1647	Serine aminopeptidase, S33
KPL75_12225	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KPL75_12230	COG1346	cytolysis
KPL75_12245	COG0148	phosphopyruvate hydratase activity
KPL75_12260	COG0126	phosphoglycerate kinase activity
KPL75_12265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KPL75_12280	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
KPL75_12310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPL75_12325	COG2323	membrane
KPL75_12335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPL75_12340	COG1481	regulation of sporulation
KPL75_12345	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KPL75_12350	COG1660	Displays ATPase and GTPase activities
KPL75_12355	COG1051	belongs to the nudix hydrolase family
KPL75_12365	COG0492	ferredoxin-NADP+ reductase activity
KPL75_12370	COG0457	Tetratricopeptide repeat
KPL75_12375	COG0110	maltose O-acetyltransferase activity
KPL75_12380	COG0546	phosphoglycolate phosphatase activity
KPL75_12385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KPL75_12390	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KPL75_12395	COG1950	PFAM Membrane protein of
KPL75_12400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPL75_12420	COG0789	Transcriptional regulator
KPL75_12450	COG0583	DNA-binding transcription factor activity
KPL75_12460	COG0655	NAD(P)H dehydrogenase (quinone) activity
KPL75_12465	COG0488	(ABC) transporter
KPL75_12475	COG1132	(ABC) transporter
KPL75_12480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPL75_12485	COG0793	Belongs to the peptidase S41A family
KPL75_12485	COG3409	Peptidoglycan-binding domain 1 protein
KPL75_12490	COG2177	Part of the ABC transporter FtsEX involved in
KPL75_12495	COG2884	Cell division ATP-binding protein ftsE
KPL75_12520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KPL75_12525	COG1278	Cold shock
KPL75_12530	COG1040	competence protein
KPL75_12535	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KPL75_12540	COG0791	NLP P60 protein
KPL75_12540	COG1388	LysM domain
KPL75_12545	COG1733	regulation of RNA biosynthetic process
KPL75_12550	COG1307	EDD domain protein, DegV family
KPL75_12555	COG1739	Uncharacterized protein family UPF0029
KPL75_12560	COG1316	TRANSCRIPTIONal
KPL75_12565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KPL75_12570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KPL75_12575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KPL75_12585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KPL75_12585	COG3933	PFAM sigma-54 factor interaction domain-containing protein
KPL75_12605	COG1486	melibiose metabolic process
KPL75_12610	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPL75_12615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPL75_12625	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPL75_12635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPL75_12640	COG1301	dicarboxylic acid transport
KPL75_12655	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KPL75_12665	COG1271	oxidase subunit
KPL75_12670	COG1294	oxidase, subunit
KPL75_12675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KPL75_12680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KPL75_12685	COG1620	l-lactate permease
KPL75_12695	COG2389	metal-binding protein
KPL75_12705	COG1368	sulfuric ester hydrolase activity
KPL75_12715	COG0791	NLP P60 protein
KPL75_12715	COG1388	LysM domain
KPL75_12720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_12730	COG1215	transferase activity, transferring glycosyl groups
KPL75_12735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KPL75_12740	COG1388	LysM domain
KPL75_12740	COG3584	3D domain protein
KPL75_12750	COG4715	Zinc finger, swim domain protein
KPL75_12755	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KPL75_12795	COG0577	efflux transmembrane transporter activity
KPL75_12800	COG1136	(ABC) transporter
KPL75_12835	COG3850	Histidine kinase
KPL75_12835	COG5002	protein histidine kinase activity
KPL75_12840	COG0745	RESPONSE REGULATOR receiver
KPL75_12845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KPL75_12860	COG1091	dTDP-4-dehydrorhamnose reductase activity
KPL75_12875	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPL75_12890	COG0110	maltose O-acetyltransferase activity
KPL75_12940	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KPL75_12945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KPL75_12950	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KPL75_12955	COG4464	protein tyrosine phosphatase activity
KPL75_12960	COG0489	protein tyrosine kinase activity
KPL75_12965	COG3944	biosynthesis protein
KPL75_12970	COG0489	protein tyrosine kinase activity
KPL75_12985	COG1609	Transcriptional regulator
KPL75_12995	COG0739	heme binding
KPL75_13010	COG4555	ABC transporter
KPL75_13015	COG2385	sporulation resulting in formation of a cellular spore
KPL75_13030	COG4836	Membrane
KPL75_13035	COG1007	ATP synthesis coupled electron transport
KPL75_13040	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_13045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KPL75_13050	COG0713	ATP synthesis coupled electron transport
KPL75_13055	COG0839	Belongs to the complex I subunit 6 family
KPL75_13065	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KPL75_13070	COG0649	NAD binding
KPL75_13075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_13080	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_13085	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KPL75_13090	COG5001	Diguanylate cyclase
KPL75_13090	COG3300	MHYT domain
KPL75_13105	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KPL75_13110	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KPL75_13115	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KPL75_13120	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KPL75_13125	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KPL75_13130	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KPL75_13140	COG0356	it plays a direct role in the translocation of protons across the membrane
KPL75_13165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KPL75_13175	COG0698	ribose 5-phosphate isomerase
KPL75_13185	COG2190	(PTS) system
KPL75_13190	COG2259	Doxx family
KPL75_13195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KPL75_13205	COG1971	Probably functions as a manganese efflux pump
KPL75_13210	COG0009	L-threonylcarbamoyladenylate synthase
KPL75_13225	COG2890	protein-(glutamine-N5) methyltransferase activity
KPL75_13230	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KPL75_13235	COG1435	thymidine kinase activity
KPL75_13245	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KPL75_13250	COG1494	fructose-1,6-bisphosphatase
KPL75_13270	COG4821	SIS domain
KPL75_13275	COG0504	CTP synthase activity
KPL75_13290	COG1960	acyl-CoA dehydrogenase activity
KPL75_13295	COG1960	acyl-CoA dehydrogenase activity
KPL75_13300	COG1250	3-hydroxyacyl-CoA dehydrogenase
KPL75_13305	COG0183	Belongs to the thiolase family
KPL75_13310	COG0247	lactate metabolic process
KPL75_13310	COG2181	nitrate reductase activity
KPL75_13315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_13320	COG4294	response to UV
KPL75_13325	COG5001	Diguanylate cyclase
KPL75_13325	COG3300	MHYT domain
KPL75_13340	COG3227	Zinc metalloprotease (Elastase)
KPL75_13345	COG2197	response regulator
KPL75_13350	COG4585	Histidine kinase
KPL75_13355	COG0842	Transport permease protein
KPL75_13360	COG1131	(ABC) transporter
KPL75_13365	COG0024	Methionine aminopeptidase
KPL75_13375	COG2234	aminopeptidase activity
KPL75_13390	COG4506	Protein conserved in bacteria
KPL75_13395	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_13420	COG2814	Major facilitator Superfamily
KPL75_13425	COG0789	Transcriptional regulator
KPL75_13430	COG0584	glycerophosphoryl diester phosphodiesterase
KPL75_13435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_13445	COG1994	Peptidase M50
KPL75_13455	COG1078	dGTPase activity
KPL75_13460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_13465	COG1120	ATPase activity
KPL75_13470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_13475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_13480	COG4844	belongs to the
KPL75_13495	COG0280	phosphate acetyltransferase
KPL75_13500	COG3253	May function as heme-dependent peroxidase
KPL75_13510	COG3773	Cell wall hydrolase
KPL75_13520	COG2363	Small membrane protein
KPL75_13530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KPL75_13535	COG2233	PERMEase
KPL75_13540	COG0561	phosphatase activity
KPL75_13545	COG2814	Major facilitator Superfamily
KPL75_13550	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KPL75_13555	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
KPL75_13560	COG1131	(ABC) transporter
KPL75_13565	COG2755	lipolytic protein G-D-S-L family
KPL75_13570	COG1609	Transcriptional regulator
KPL75_13580	COG0460	homoserine dehydrogenase
KPL75_13585	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KPL75_13590	COG2873	o-acetylhomoserine
KPL75_13600	COG1011	Hydrolase
KPL75_13605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KPL75_13615	COG2197	response regulator
KPL75_13620	COG2203	Gaf domain
KPL75_13620	COG4585	Histidine kinase
KPL75_13625	COG0351	phosphomethylpyrimidine kinase
KPL75_13630	COG3706	GGDEF domain
KPL75_13635	COG2879	small protein
KPL75_13640	COG1966	Carbon starvation protein
KPL75_13645	COG3279	Response regulator of the LytR AlgR family
KPL75_13650	COG0477	Major facilitator Superfamily
KPL75_13675	COG0840	transmembrane signaling receptor activity
KPL75_13685	COG1607	acyl-coa hydrolase
KPL75_13690	COG1216	Glycosyl transferase, family 2
KPL75_13700	COG1216	Glycosyl transferase, family 2
KPL75_13715	COG0488	(ABC) transporter
KPL75_13730	COG0463	Glycosyl transferase, family 2
KPL75_13735	COG1309	transcriptional regulator
KPL75_13740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KPL75_13745	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPL75_13745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPL75_13750	COG0628	permease
KPL75_13760	COG1380	Effector of murein hydrolase LrgA
KPL75_13765	COG3279	Response regulator of the LytR AlgR family
KPL75_13770	COG3275	phosphorelay sensor kinase activity
KPL75_13780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KPL75_13785	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KPL75_13820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KPL75_13825	COG1272	protein, Hemolysin III
KPL75_13850	COG1164	Oligoendopeptidase f
KPL75_13865	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KPL75_13875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KPL75_13880	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KPL75_13885	COG4853	Protein conserved in bacteria
KPL75_13895	COG5002	protein histidine kinase activity
KPL75_13900	COG0745	RESPONSE REGULATOR receiver
KPL75_13930	COG0305	Participates in initiation and elongation during chromosome replication
KPL75_13940	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
KPL75_13945	COG4241	membrane
KPL75_13955	COG0629	single-stranded DNA binding
KPL75_13960	COG0360	Binds together with S18 to 16S ribosomal RNA
KPL75_13965	COG0012	GTP binding
KPL75_13970	COG4481	Protein conserved in bacteria
KPL75_13975	COG0668	transmembrane transport
KPL75_13985	COG1475	DNA binding
KPL75_13990	COG1192	Involved in chromosome partitioning
KPL75_13995	COG1475	DNA binding
KPL75_14000	COG0357	Ribosomal RNA small subunit methyltransferase G
KPL75_14005	COG0445	tRNA wobble uridine modification
KPL75_14010	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KPL75_14015	COG1847	R3H domain protein
KPL75_14020	COG0706	membrane insertase activity
KPL75_14025	COG0594	ribonuclease P activity
KPL75_14030	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KPL75_14035	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KPL75_14040	COG0592	DNA-directed DNA polymerase activity
KPL75_14045	COG2501	S4 domain
KPL75_14050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KPL75_14055	COG0187	DNA topoisomerase II activity
KPL75_14060	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KPL75_14095	COG0516	GMP reductase activity
KPL75_14095	COG0517	IMP dehydrogenase activity
KPL75_14100	COG1686	Belongs to the peptidase S11 family
KPL75_14110	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KPL75_14130	COG1428	Deoxynucleoside kinase
KPL75_14135	COG1428	Deoxynucleoside kinase
KPL75_14140	COG1335	isochorismatase
KPL75_14145	COG0590	tRNA wobble adenosine to inosine editing
KPL75_14155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KPL75_14165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KPL75_14210	COG1982	Orn Lys Arg decarboxylase major
KPL75_14215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KPL75_14220	COG0470	DNA polymerase III
KPL75_14225	COG1774	PSP1 C-terminal conserved region
KPL75_14230	COG4467	Involved in initiation control of chromosome replication
KPL75_14235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KPL75_14245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KPL75_14250	COG2002	toxin-antitoxin pair type II binding
KPL75_14260	COG0084	hydrolase, TatD family'
KPL75_14265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KPL75_14270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KPL75_14280	COG4466	Protein conserved in bacteria
KPL75_14295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KPL75_14300	COG0251	oxidation-reduction process
KPL75_14305	COG2088	sporulation resulting in formation of a cellular spore
KPL75_14310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KPL75_14330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KPL75_14335	COG2002	toxin-antitoxin pair type II binding
KPL75_14340	COG2244	polysaccharide biosynthetic process
KPL75_14345	COG3956	TIGRFAM MazG family protein
KPL75_14350	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KPL75_14370	COG1098	S1 RNA binding domain
KPL75_14385	COG2208	phosphoserine phosphatase activity
KPL75_14395	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KPL75_14400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KPL75_14410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KPL75_14415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KPL75_14420	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KPL75_14425	COG0512	Glutamine amidotransferase of anthranilate synthase
KPL75_14430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KPL75_14435	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KPL75_14440	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KPL75_14445	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KPL75_14450	COG1396	sequence-specific DNA binding
KPL75_14455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPL75_14545	COG3880	PFAM UvrB UvrC protein
KPL75_14550	COG3869	Catalyzes the specific phosphorylation of arginine residues in
KPL75_14555	COG0542	response to heat
KPL75_14560	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KPL75_14565	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KPL75_14570	COG4956	integral membrane protein (PIN domain superfamily)
KPL75_14575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KPL75_14585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KPL75_14590	COG1045	serine acetyltransferase
KPL75_14595	COG0215	cysteine-tRNA ligase activity
KPL75_14605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KPL75_14610	COG3688	RNA-binding protein containing a PIN domain
KPL75_14620	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KPL75_14625	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KPL75_14630	COG0250	Participates in transcription elongation, termination and antitermination
KPL75_14635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KPL75_14640	COG0081	regulation of translation
KPL75_14645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KPL75_14650	COG0222	ribosome binding
KPL75_14655	COG2813	Specifically methylates the guanine in position
KPL75_14660	COG0085	RNA polymerase activity
KPL75_14665	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KPL75_14670	COG1358	cellular component organization or biogenesis
KPL75_14675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KPL75_14685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KPL75_14690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KPL75_14695	COG0051	transcription antitermination factor activity, RNA binding
KPL75_14700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KPL75_14705	COG0088	Forms part of the polypeptide exit tunnel
KPL75_14710	COG0089	rRNA binding
KPL75_14715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KPL75_14740	COG0255	Belongs to the universal ribosomal protein uL29 family
KPL75_14745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KPL75_14755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KPL75_14760	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KPL75_14770	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KPL75_14780	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KPL75_14790	COG1841	ribosomal large subunit assembly
KPL75_14795	COG0200	Binds to the 23S rRNA
KPL75_14800	COG0201	protein transport
KPL75_14805	COG0563	adenylate kinase activity
KPL75_14810	COG0024	Methionine aminopeptidase
KPL75_14820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KPL75_14825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KPL75_14830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KPL75_14855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KPL75_14865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KPL75_14880	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_14885	COG0489	protein tyrosine kinase activity
KPL75_14895	COG2194	sulfuric ester hydrolase activity
KPL75_14900	COG0726	polysaccharide deacetylase
KPL75_14980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KPL75_14985	COG4856	YbbR-like protein
KPL75_15005	COG0823	Involved in the tonB-independent uptake of proteins
KPL75_15005	COG4946	Tricorn protease homolog
KPL75_15005	COG1506	peptidase
KPL75_15040	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_15045	COG2011	ABC-type metal ion transport system permease component
KPL75_15055	COG1464	Belongs to the NlpA lipoprotein family
KPL75_15060	COG0604	alcohol dehydrogenase
KPL75_15065	COG0277	FAD linked oxidase domain protein
KPL75_15070	COG2271	Major facilitator Superfamily
KPL75_15080	COG2814	Major facilitator Superfamily
KPL75_15100	COG0601	transmembrane transport
KPL75_15105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_15110	COG0444	Belongs to the ABC transporter superfamily
KPL75_15115	COG4608	Belongs to the ABC transporter superfamily
KPL75_15120	COG4166	transmembrane transport
KPL75_15130	COG1309	transcriptional regulator
KPL75_15140	COG4166	transmembrane transport
KPL75_15145	COG4166	transmembrane transport
KPL75_15150	COG0656	L-ascorbic acid biosynthetic process
KPL75_15170	COG4149	molybdate abc transporter
KPL75_15175	COG0725	ABC transporter, periplasmic molybdate-binding protein
KPL75_15180	COG1910	domain protein
KPL75_15195	COG0697	spore germination
KPL75_15210	COG0204	Acyl-transferase
KPL75_15220	COG1609	Transcriptional regulator
KPL75_15230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_15245	COG5298	Protein conserved in bacteria
KPL75_15270	COG0488	(ABC) transporter
KPL75_15275	COG4585	Histidine kinase
KPL75_15280	COG2197	response regulator
KPL75_15285	COG1131	(ABC) transporter
KPL75_15290	COG1511	domain protein
KPL75_15290	COG0842	Transport permease protein
KPL75_15295	COG0842	Transport permease protein
KPL75_15305	COG0747	negative chemotaxis
KPL75_15310	COG0747	negative chemotaxis
KPL75_15315	COG0601	transmembrane transport
KPL75_15320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_15325	COG0444	Belongs to the ABC transporter superfamily
KPL75_15330	COG4608	Belongs to the ABC transporter superfamily
KPL75_15335	COG0561	phosphatase activity
KPL75_15375	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KPL75_15380	COG0179	Fumarylacetoacetate (FAA) hydrolase
KPL75_15390	COG0531	amino acid
KPL75_15395	COG2814	Major facilitator Superfamily
KPL75_15405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KPL75_15415	COG4294	response to UV
KPL75_15420	COG0705	Rhomboid family
KPL75_15425	COG0736	holo-[acyl-carrier-protein] synthase activity
KPL75_15430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KPL75_15435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPL75_15440	COG0864	Transcriptional regulator
KPL75_15445	COG2337	Toxic component of a toxin-antitoxin (TA) module
KPL75_15450	COG2183	response to ionizing radiation
KPL75_15550	COG0802	atpase or kinase
KPL75_15555	COG1214	PFAM Peptidase M22, glycoprotease
KPL75_15560	COG0456	acetyltransferase
KPL75_15570	COG0488	(ABC) transporter
KPL75_15575	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KPL75_15585	COG1266	CAAX protease self-immunity
KPL75_15590	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KPL75_15595	COG0459	protein refolding
KPL75_15600	COG0519	Catalyzes the synthesis of GMP from XMP
KPL75_15600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KPL75_15605	COG2252	PERMEase
KPL75_15615	COG5002	protein histidine kinase activity
KPL75_15640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KPL75_15675	COG2226	methyltransferase
KPL75_15685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KPL75_15695	COG1215	transferase activity, transferring glycosyl groups
KPL75_15755	COG0697	spore germination
KPL75_15780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KPL75_15785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KPL75_15790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KPL75_15800	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KPL75_15805	COG0047	phosphoribosylformylglycinamidine synthase activity
KPL75_15815	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KPL75_15825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KPL75_15830	COG0138	bifunctional purine biosynthesis protein purh
KPL75_15835	COG0151	Belongs to the GarS family
KPL75_15855	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KPL75_15860	COG0210	DNA helicase
KPL75_15865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KPL75_15870	COG4851	CamS sex pheromone cAM373 precursor
KPL75_15880	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_15885	COG1335	isochorismatase
KPL75_15895	COG2011	ABC-type metal ion transport system permease component
KPL75_15900	COG1464	Belongs to the NlpA lipoprotein family
KPL75_15915	COG0003	Pfam Anion-transporting ATPase
KPL75_15920	COG1846	Transcriptional regulator
KPL75_15925	COG4682	membrane
KPL75_15940	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KPL75_15945	COG1597	lipid kinase activity
KPL75_15955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPL75_15965	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_15970	COG2076	Multidrug Resistance protein
KPL75_15975	COG2309	aminopeptidase activity
KPL75_15990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_16000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KPL75_16005	COG5002	protein histidine kinase activity
KPL75_16015	COG4807	Protein conserved in bacteria
KPL75_16040	COG1757	Na H antiporter
KPL75_16045	COG1473	amidohydrolase
KPL75_16060	COG0450	alkyl hydroperoxide reductase
KPL75_16070	COG3279	Response regulator of the LytR AlgR family
KPL75_16075	COG2972	Histidine kinase
KPL75_16075	COG0745	RESPONSE REGULATOR receiver
KPL75_16085	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KPL75_16095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_16100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_16105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_16110	COG0492	ferredoxin-NADP+ reductase activity
KPL75_16120	COG0166	Belongs to the GPI family
KPL75_16145	COG5002	protein histidine kinase activity
KPL75_16165	COG3541	Predicted nucleotidyltransferase
KPL75_16170	COG2814	Major facilitator Superfamily
KPL75_16175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_16175	COG0723	plastoquinol--plastocyanin reductase activity
KPL75_16185	COG0765	amino acid transport
KPL75_16190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_16200	COG0840	transmembrane signaling receptor activity
KPL75_16205	COG0277	FAD linked oxidase domain protein
KPL75_16210	COG0366	Alpha amylase catalytic
KPL75_16215	COG2190	(PTS) system
KPL75_16215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_16215	COG1263	PTS System
KPL75_16235	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KPL75_16240	COG0352	thiamine-phosphate diphosphorylase activity
KPL75_16245	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KPL75_16260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_16265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_16270	COG1116	anion transmembrane transporter activity
KPL75_16280	COG0488	(ABC) transporter
KPL75_16320	COG2270	Major facilitator Superfamily
KPL75_16350	COG2310	stress, protein
KPL75_16355	COG2310	stress, protein
KPL75_16360	COG2310	stress, protein
KPL75_16365	COG0861	Integral membrane protein TerC family
KPL75_16375	COG3853	Toxic anion resistance protein (TelA)
KPL75_16385	COG4840	Belongs to the UPF0435 family
KPL75_16390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KPL75_16400	COG1295	ribonuclease BN
KPL75_16405	COG2217	Heavy metal translocating P-type atpase
KPL75_16410	COG0697	spore germination
KPL75_16430	COG0586	Pfam SNARE associated Golgi protein
KPL75_16445	COG3871	stress protein (general stress protein 26)
KPL75_16450	COG0387	Pfam Sodium calcium exchanger
KPL75_16460	COG0535	radical SAM domain protein
KPL75_16480	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KPL75_16500	COG3829	transcription factor binding
KPL75_16510	COG0833	amino acid
KPL75_16540	COG1263	PTS System
KPL75_16540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_16545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_16560	COG1216	Glycosyl transferase, family 2
KPL75_16570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KPL75_16570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KPL75_16575	COG0463	Glycosyl transferase, family 2
KPL75_16590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KPL75_16595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KPL75_16610	COG1228	amidohydrolase
KPL75_16615	COG1090	epimerase
KPL75_16620	COG2137	regulation of response to DNA damage stimulus
KPL75_16645	COG1988	membrane-bound metal-dependent
KPL75_16650	COG1194	a g-specific adenine glycosylase
KPL75_16670	COG3557	Belongs to the UPF0374 family
KPL75_16675	COG1132	(ABC) transporter
KPL75_16680	COG4129	membrane
KPL75_16685	COG0067	glutamate synthase
KPL75_16685	COG0069	glutamate synthase activity
KPL75_16685	COG0070	glutamate synthase
KPL75_16690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KPL75_16695	COG4555	ABC transporter
KPL75_16715	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KPL75_16720	COG0735	belongs to the Fur family
KPL75_16835	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KPL75_16840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KPL75_16860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KPL75_16870	COG2766	serine protein kinase
KPL75_16875	COG2718	Belongs to the UPF0229 family
KPL75_16890	COG1585	Membrane protein implicated in regulation of membrane protease activity
KPL75_16895	COG2268	Band 7 protein
KPL75_16905	COG3290	protein histidine kinase activity
KPL75_16910	COG4565	transcriptional regulatory protein
KPL75_16915	COG2851	Citrate transporter
KPL75_16940	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KPL75_16945	COG3842	ATPase activity
KPL75_16950	COG1175	transmembrane transport
KPL75_16955	COG0395	ABC-type sugar transport system, permease component
KPL75_16965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KPL75_16970	COG0745	RESPONSE REGULATOR receiver
KPL75_16975	COG5002	protein histidine kinase activity
KPL75_16985	COG4990	cell redox homeostasis
KPL75_16995	COG3290	protein histidine kinase activity
KPL75_17000	COG4565	transcriptional regulatory protein
KPL75_17005	COG3493	citrate carrier protein
KPL75_17010	COG0281	malic enzyme
KPL75_17020	COG0697	spore germination
KPL75_17025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_17035	COG5002	protein histidine kinase activity
KPL75_17040	COG0745	RESPONSE REGULATOR receiver
KPL75_17045	COG0456	acetyltransferase
KPL75_17050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KPL75_17055	COG3383	formate dehydrogenase (NAD+) activity
KPL75_17060	COG2427	Protein of unknown function (DUF1641)
KPL75_17075	COG0531	amino acid
KPL75_17085	COG0640	Transcriptional regulator
KPL75_17090	COG2217	Heavy metal translocating P-type atpase
KPL75_17095	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KPL75_17110	COG3227	Zinc metalloprotease (Elastase)
KPL75_17130	COG2720	vancomycin resistance protein
KPL75_17135	COG1316	TRANSCRIPTIONal
KPL75_17140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_17145	COG0346	lactoylglutathione lyase activity
KPL75_17150	COG1253	flavin adenine dinucleotide binding
KPL75_17155	COG1027	Aspartate ammonia-lyase
KPL75_17160	COG1620	l-lactate permease
KPL75_17175	COG3104	oligopeptide transport
KPL75_17180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_17185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_17190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KPL75_17210	COG0156	8-amino-7-oxononanoate synthase activity
KPL75_17215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KPL75_17220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KPL75_17230	COG4548	von Willebrand factor, type A
KPL75_17235	COG0714	Associated with various cellular activities
KPL75_17240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_17260	COG0531	amino acid
KPL75_17265	COG2188	Transcriptional regulator
KPL75_17270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_17270	COG1263	PTS System
KPL75_17275	COG0366	Alpha amylase catalytic
KPL75_17290	COG0697	spore germination
KPL75_17300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KPL75_17305	COG1115	amino acid carrier protein
KPL75_17310	COG1126	abc transporter atp-binding protein
KPL75_17315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_17320	COG0765	amino acid transport
KPL75_17325	COG0765	amino acid transport
KPL75_17330	COG0833	amino acid
KPL75_17345	COG1595	DNA-templated transcription, initiation
KPL75_17355	COG2378	regulation of single-species biofilm formation
KPL75_17360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPL75_17365	COG5002	protein histidine kinase activity
KPL75_17385	COG2814	Major facilitator Superfamily
KPL75_17390	COG0659	secondary active sulfate transmembrane transporter activity
KPL75_17405	COG0747	negative chemotaxis
KPL75_17415	COG0601	transmembrane transport
KPL75_17420	COG4608	Belongs to the ABC transporter superfamily
KPL75_17430	COG2271	Major facilitator Superfamily
KPL75_17435	COG1846	Transcriptional regulator
KPL75_17440	COG0477	Major facilitator Superfamily
KPL75_17445	COG1609	Transcriptional regulator
KPL75_17450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KPL75_17455	COG1869	D-ribose catabolic process
KPL75_17465	COG1172	Belongs to the binding-protein-dependent transport system permease family
KPL75_17470	COG1879	ABC-type sugar transport system periplasmic component
KPL75_17500	COG1063	alcohol dehydrogenase
KPL75_17515	COG3568	Endonuclease Exonuclease Phosphatase
KPL75_17545	COG0840	transmembrane signaling receptor activity
KPL75_17550	COG3584	3D domain protein
KPL75_17550	COG1388	LysM domain
KPL75_17555	COG1476	TRANSCRIPTIONal
KPL75_17575	COG3104	oligopeptide transport
KPL75_17585	COG1114	Component of the transport system for branched-chain amino acids
KPL75_17600	COG1113	amino acid transport
KPL75_17605	COG2252	PERMEase
KPL75_17620	COG2153	protein acetylation
KPL75_17630	COG0569	domain protein
KPL75_17630	COG0475	glutathione-regulated potassium exporter activity
KPL75_17640	COG1845	cytochrome c oxidase, subunit III
KPL75_17645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KPL75_17655	COG0833	amino acid
KPL75_17660	COG4990	cell redox homeostasis
KPL75_17680	COG0697	spore germination
KPL75_17685	COG0531	amino acid
KPL75_17700	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KPL75_17705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KPL75_17710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KPL75_17710	COG1918	ferrous iron import across plasma membrane
KPL75_17715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KPL75_17720	COG0573	inorganic phosphate transmembrane transporter activity
KPL75_17725	COG0581	inorganic phosphate transmembrane transporter activity
KPL75_17735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KPL75_17855	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KPL75_17870	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_17870	COG3103	Sh3 type 3 domain protein
KPL75_17870	COG4991	sh3 domain protein
KPL75_17875	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KPL75_17880	COG1116	anion transmembrane transporter activity
KPL75_17885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KPL75_17890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KPL75_17895	COG0352	thiamine-phosphate diphosphorylase activity
KPL75_17900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_17905	COG2104	thiamine diphosphate biosynthetic process
KPL75_17915	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_17920	COG0351	phosphomethylpyrimidine kinase
KPL75_17945	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KPL75_17950	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KPL75_17955	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KPL75_17960	COG2205	protein histidine kinase activity
KPL75_17965	COG2814	Major facilitator Superfamily
KPL75_17970	COG1846	Transcriptional regulator
KPL75_17990	COG1172	Belongs to the binding-protein-dependent transport system permease family
KPL75_17995	COG1129	ABC transporter
KPL75_18005	COG2252	PERMEase
KPL75_18010	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_18015	COG1376	ErfK ybiS ycfS ynhG family protein
KPL75_18070	COG0778	Nitroreductase
KPL75_18075	COG2719	SpoVR family
KPL75_18095	COG3591	Belongs to the peptidase S1B family
KPL75_18105	COG1937	Protein conserved in bacteria
KPL75_18110	COG0425	Belongs to the sulfur carrier protein TusA family
KPL75_18110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_18115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_18115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_18120	COG0425	Belongs to the sulfur carrier protein TusA family
KPL75_18125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_18125	COG0425	Belongs to the sulfur carrier protein TusA family
KPL75_18130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KPL75_18135	COG2210	Belongs to the sulfur carrier protein TusA family
KPL75_18140	COG0730	response to heat
KPL75_18150	COG1316	TRANSCRIPTIONal
KPL75_18155	COG0604	alcohol dehydrogenase
KPL75_18160	COG1283	sodium-dependent phosphate transmembrane transporter activity
KPL75_18165	COG2814	Major facilitator Superfamily
KPL75_18175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KPL75_18175	COG3711	transcriptional antiterminator
KPL75_18180	COG1447	Phosphotransferase system cellobiose-specific component IIA
KPL75_18185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KPL75_18205	COG1388	LysM domain
KPL75_18205	COG3584	3D domain protein
KPL75_18210	COG0577	efflux transmembrane transporter activity
KPL75_18215	COG1136	(ABC) transporter
KPL75_18225	COG5522	Integral membrane protein (intg_mem_TP0381)
KPL75_18240	COG0577	efflux transmembrane transporter activity
KPL75_18245	COG1114	Component of the transport system for branched-chain amino acids
KPL75_18250	COG3546	catalase activity
KPL75_18275	COG0586	Pfam SNARE associated Golgi protein
KPL75_18305	COG0531	amino acid
KPL75_18310	COG0475	glutathione-regulated potassium exporter activity
KPL75_18320	COG1737	Transcriptional regulator
KPL75_18330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_18330	COG1263	PTS System
KPL75_18340	COG2259	Doxx family
KPL75_18360	COG1522	sequence-specific DNA binding
KPL75_18385	COG2076	Multidrug Resistance protein
KPL75_18390	COG1309	transcriptional regulator
KPL75_18395	COG2814	Major facilitator Superfamily
KPL75_18400	COG1733	regulation of RNA biosynthetic process
KPL75_18410	COG2249	NAD(P)H dehydrogenase (quinone) activity
KPL75_18420	COG4533	DNA binding
KPL75_18425	COG2211	Major facilitator Superfamily
KPL75_18440	COG0531	amino acid
KPL75_18445	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_18450	COG1132	(ABC) transporter
KPL75_18455	COG1132	(ABC) transporter
KPL75_18460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KPL75_18465	COG0765	amino acid transport
KPL75_18470	COG1126	abc transporter atp-binding protein
KPL75_18485	COG0189	ligase activity
KPL75_18495	COG4399	Belongs to the UPF0754 family
KPL75_18500	COG3679	Belongs to the UPF0342 family
KPL75_18515	COG0028	Belongs to the TPP enzyme family
KPL75_18520	COG3527	Alpha-acetolactate decarboxylase
KPL75_18525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPL75_18535	COG0561	phosphatase activity
KPL75_18545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KPL75_18560	COG0586	Pfam SNARE associated Golgi protein
KPL75_18570	COG4978	Transcriptional regulator
KPL75_18570	COG0789	Transcriptional regulator
KPL75_18580	COG0659	secondary active sulfate transmembrane transporter activity
KPL75_18600	COG2244	polysaccharide biosynthetic process
KPL75_18615	COG1361	Conserved repeat domain
KPL75_18630	COG1024	Enoyl-CoA hydratase
KPL75_18645	COG1363	Peptidase, m42
KPL75_18680	COG0579	oxidoreductase
KPL75_18700	COG0601	transmembrane transport
KPL75_18705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_18710	COG0444	Belongs to the ABC transporter superfamily
KPL75_18715	COG4608	Belongs to the ABC transporter superfamily
KPL75_18815	COG0477	Major facilitator Superfamily
KPL75_18820	COG3290	protein histidine kinase activity
KPL75_18825	COG4565	transcriptional regulatory protein
KPL75_18830	COG3181	Tripartite tricarboxylate transporter family receptor
KPL75_18875	COG4978	Transcriptional regulator
KPL75_18875	COG0789	Transcriptional regulator
KPL75_18890	COG0305	Participates in initiation and elongation during chromosome replication
KPL75_18915	COG1842	Phage shock protein A
KPL75_18930	COG0477	Major facilitator Superfamily
KPL75_18970	COG2814	Major facilitator Superfamily
KPL75_18975	COG0640	Transcriptional regulator
KPL75_18980	COG3711	transcriptional antiterminator
KPL75_18985	COG2190	(PTS) system
KPL75_18985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KPL75_18985	COG1263	PTS System
KPL75_18990	COG2723	6-phospho-beta-galactosidase activity
KPL75_19005	COG2376	Dihydroxyacetone kinase
KPL75_19015	COG2376	Dihydroxyacetone kinase
KPL75_19035	COG1335	isochorismatase
KPL75_19085	COG2801	Transposase and inactivated derivatives
KPL75_19100	COG0076	glutamate decarboxylase activity
KPL75_19125	COG1388	LysM domain
KPL75_19145	COG2807	transmembrane transport
KPL75_19165	COG4585	Histidine kinase
KPL75_19170	COG2197	response regulator
KPL75_19200	COG0420	3'-5' exonuclease activity
KPL75_19205	COG4717	serine-type aminopeptidase activity
KPL75_19210	COG3481	metal-dependent phosphohydrolase, HD sub domain
KPL75_19220	COG0346	lactoylglutathione lyase activity
KPL75_19225	COG0346	lactoylglutathione lyase activity
KPL75_19240	COG2267	carboxylic ester hydrolase activity
KPL75_19250	COG2140	Oxalate decarboxylase
KPL75_19255	COG3620	sequence-specific DNA binding
KPL75_19260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KPL75_19265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KPL75_19270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KPL75_19275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KPL75_19290	COG1595	DNA-templated transcription, initiation
KPL75_19300	COG0772	Belongs to the SEDS family
KPL75_19310	COG3973	AAA domain
KPL75_19330	COG1846	Transcriptional regulator
KPL75_19340	COG0537	adenosine 5'-monophosphoramidase activity
KPL75_19345	COG1131	(ABC) transporter
KPL75_19350	COG4473	ABC transporter
KPL75_19360	COG0247	lactate metabolic process
KPL75_19365	COG1139	Iron-sulfur cluster binding protein
KPL75_19370	COG1556	Lactate utilization protein
KPL75_19390	COG3402	PFAM membrane-flanked domain
KPL75_19395	COG3428	Bacterial PH domain
KPL75_19435	COG1136	(ABC) transporter
KPL75_19440	COG0577	efflux transmembrane transporter activity
KPL75_19460	COG3402	PFAM membrane-flanked domain
KPL75_19465	COG3428	Bacterial PH domain
KPL75_19470	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_19475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_19490	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KPL75_19530	COG1309	transcriptional regulator
KPL75_19535	COG1511	domain protein
KPL75_19535	COG1511	domain protein
KPL75_19570	COG2378	regulation of single-species biofilm formation
KPL75_19575	COG1609	Transcriptional regulator
KPL75_19585	COG1234	tRNA 3'-trailer cleavage
KPL75_19590	COG0095	Lipoate-protein ligase
KPL75_19595	COG0318	PFAM AMP-dependent synthetase and ligase
KPL75_19605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KPL75_19615	COG4208	sulfate ABC transporter
KPL75_19630	COG1408	metallophosphoesterase
KPL75_19635	COG1078	dGTPase activity
KPL75_19650	COG1595	DNA-templated transcription, initiation
KPL75_19655	COG3708	Transcriptional regulator
KPL75_19655	COG2207	Transcriptional regulator
KPL75_19660	COG2205	protein histidine kinase activity
KPL75_19665	COG0745	RESPONSE REGULATOR receiver
KPL75_19690	COG0501	Belongs to the peptidase M48B family
KPL75_19695	COG0697	spore germination
KPL75_19710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KPL75_19715	COG2224	Isocitrate lyase
KPL75_19725	COG1278	Cold shock
KPL75_19735	COG4903	ComK protein
KPL75_19745	COG0398	Pfam SNARE associated Golgi protein
KPL75_19755	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KPL75_19815	COG0179	Fumarylacetoacetate (FAA) hydrolase
KPL75_19840	COG0367	asparagine synthase
KPL75_19855	COG0753	catalase activity
KPL75_19870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KPL75_19890	COG3339	Conserved Protein
KPL75_19895	COG0004	ammonium transporteR
KPL75_19910	COG2996	Protein conserved in bacteria
KPL75_19925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KPL75_19935	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_19950	COG0561	phosphatase activity
KPL75_19970	COG2267	carboxylic ester hydrolase activity
KPL75_19985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KPL75_19990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KPL75_19995	COG5504	Zn-dependent protease
KPL75_20010	COG0180	Tryptophanyl-tRNA synthetase
KPL75_20020	COG4166	transmembrane transport
KPL75_20025	COG0601	transmembrane transport
KPL75_20030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KPL75_20035	COG0444	Belongs to the ABC transporter superfamily
KPL75_20040	COG4608	Belongs to the ABC transporter superfamily
KPL75_20055	COG0534	Mate efflux family protein
KPL75_20060	COG4166	transmembrane transport
KPL75_20075	COG0861	Integral membrane protein TerC family
KPL75_20080	COG4862	establishment of competence for transformation
KPL75_20085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_20095	COG1164	Oligoendopeptidase f
KPL75_20110	COG2346	COG2346, Truncated hemoglobins
KPL75_20115	COG4116	CYTH
KPL75_20125	COG2357	RelA SpoT domain protein
KPL75_20135	COG0564	pseudouridine synthase activity
KPL75_20145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KPL75_20150	COG0772	Belongs to the SEDS family
KPL75_20155	COG1216	Glycosyl transferase, family 2
KPL75_20175	COG0463	Glycosyl transferase, family 2
KPL75_20175	COG0457	Tetratricopeptide repeat
KPL75_20195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KPL75_20210	COG1091	dTDP-4-dehydrorhamnose reductase activity
KPL75_20255	COG2153	protein acetylation
KPL75_20260	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KPL75_20265	COG2382	esterase
KPL75_20290	COG5492	domain, Protein
KPL75_20295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPL75_20305	COG0512	Glutamine amidotransferase of anthranilate synthase
KPL75_20305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPL75_20310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KPL75_20315	COG0134	indole-3-glycerol-phosphate synthase activity
KPL75_20320	COG0135	phosphoribosylanthranilate isomerase activity
KPL75_20325	COG0133	tryptophan synthase activity
KPL75_20330	COG0159	tryptophan synthase activity
KPL75_20340	COG1620	l-lactate permease
KPL75_20345	COG5634	Uncharacterized conserved protein (DUF2278)
KPL75_20385	COG2226	methyltransferase
KPL75_20405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KPL75_20410	COG0567	Dehydrogenase, E1 component
KPL75_20415	COG1476	TRANSCRIPTIONal
KPL75_20460	COG1686	Belongs to the peptidase S11 family
KPL75_20465	COG0681	Belongs to the peptidase S26 family
KPL75_20500	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_20510	COG1176	ABC-type spermidine putrescine transport system, permease component I
KPL75_20515	COG1177	transmembrane transport
KPL75_20520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KPL75_20530	COG2409	Drug exporters of the RND superfamily
KPL75_20540	COG0564	pseudouridine synthase activity
KPL75_20550	COG2801	Transposase and inactivated derivatives
KPL75_20560	COG2340	Cysteine-rich secretory protein family
KPL75_20565	COG0247	lactate metabolic process
KPL75_20570	COG0277	FAD linked oxidase domain protein
KPL75_20575	COG3835	regulator
KPL75_20585	COG0745	RESPONSE REGULATOR receiver
KPL75_20595	COG2186	Transcriptional regulator
KPL75_20610	COG1556	Lactate utilization protein
KPL75_20615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KPL75_20625	COG2116	formate transmembrane transporter activity
KPL75_20630	COG0861	Integral membrane protein TerC family
KPL75_20635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KPL75_20645	COG2030	dehydratase
KPL75_20665	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_20670	COG3243	poly(R)-hydroxyalkanoic acid synthase
KPL75_20680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KPL75_20695	COG1840	ABC-type Fe3 transport system, periplasmic component
KPL75_20700	COG3842	ATPase activity
KPL75_20710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KPL75_20715	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KPL75_20725	COG1349	DNA-binding transcription factor activity
KPL75_20735	COG0235	Class ii aldolase
KPL75_20745	COG2861	carbohydrate metabolic process
KPL75_20755	COG3852	Histidine kinase
KPL75_20760	COG1846	Transcriptional regulator
KPL75_20770	COG2318	DinB family
KPL75_20775	COG5002	protein histidine kinase activity
KPL75_20785	COG0720	synthase
KPL75_20800	COG4873	Protein conserved in bacteria
KPL75_20830	COG1780	Probably involved in ribonucleotide reductase function
KPL75_20845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KPL75_20850	COG0531	amino acid
KPL75_20855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KPL75_20870	COG2204	response regulator
KPL75_20875	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_20885	COG1725	Transcriptional regulator
KPL75_20890	COG1131	(ABC) transporter
KPL75_20900	COG1131	(ABC) transporter
KPL75_20910	COG1266	CAAX protease self-immunity
KPL75_20920	COG1522	sequence-specific DNA binding
KPL75_20930	COG1335	isochorismatase
KPL75_20940	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_20945	COG2070	2-Nitropropane dioxygenase
KPL75_20950	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KPL75_20955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPL75_20960	COG1696	Membrane protein involved in D-alanine export
KPL75_20985	COG0716	FMN binding
KPL75_21000	COG3173	Aminoglycoside phosphotransferase
KPL75_21020	COG0534	Mate efflux family protein
KPL75_21040	COG1846	Transcriptional regulator
KPL75_21055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KPL75_21065	COG3874	Sporulation protein YtfJ
KPL75_21090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KPL75_21095	COG0028	Belongs to the TPP enzyme family
KPL75_21100	COG0440	acetolactate synthase activity
KPL75_21110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPL75_21120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KPL75_21130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KPL75_21135	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KPL75_21150	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KPL75_21155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KPL75_21160	COG0107	imidazoleglycerol-phosphate synthase activity
KPL75_21170	COG0140	phosphoribosyl-ATP diphosphatase activity
KPL75_21175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KPL75_21190	COG1183	phosphatidylcholine synthase activity
KPL75_21195	COG1368	sulfuric ester hydrolase activity
KPL75_21205	COG0019	diaminopimelate decarboxylase activity
KPL75_21225	COG0529	Catalyzes the synthesis of activated sulfate
KPL75_21230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KPL75_21250	COG1648	precorrin-2 dehydrogenase activity
KPL75_21255	COG0733	neurotransmitter:sodium symporter activity
KPL75_21280	COG1757	Na H antiporter
KPL75_21300	COG4758	membrane
KPL75_21305	COG4585	Histidine kinase
KPL75_21310	COG2197	response regulator
KPL75_21320	COG1114	Component of the transport system for branched-chain amino acids
KPL75_21370	COG0730	response to heat
KPL75_21375	COG0306	phosphate transporter
KPL75_21380	COG1392	Phosphate transport regulator
KPL75_21385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_21400	COG3852	Histidine kinase
KPL75_21405	COG1801	Protein of unknown function DUF72
KPL75_21415	COG0582	viral genome integration into host DNA
KPL75_21420	COG5002	protein histidine kinase activity
KPL75_21435	COG0392	lysyltransferase activity
KPL75_21435	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KPL75_21450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KPL75_21455	COG1686	Belongs to the peptidase S11 family
KPL75_21460	COG2715	membrane protein required for spore maturation
KPL75_21465	COG0700	Nucleoside recognition
KPL75_21470	COG1187	pseudouridine synthase activity
KPL75_21480	COG1333	cytochrome c biogenesis protein
KPL75_21485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KPL75_21490	COG0745	RESPONSE REGULATOR receiver
KPL75_21495	COG5002	protein histidine kinase activity
KPL75_21500	COG2096	Adenosyltransferase
KPL75_21505	COG4942	peptidase
KPL75_21515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KPL75_21520	COG1141	Ferredoxin
KPL75_21525	COG4955	Helix-turn-helix domain
KPL75_21530	COG0514	ATP-dependent DNA helicase (RecQ)
KPL75_21535	COG1266	CAAX protease self-immunity
KPL75_21545	COG1408	metallophosphoesterase
KPL75_21560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KPL75_21580	COG0492	ferredoxin-NADP+ reductase activity
KPL75_21585	COG0252	asparaginase activity
KPL75_21595	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KPL75_21605	COG1304	FMN binding
KPL75_21640	COG1160	GTP binding
KPL75_21665	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KPL75_21680	COG0142	geranyltranstransferase activity
KPL75_21685	COG2226	methyltransferase
KPL75_21690	COG0142	geranyltranstransferase activity
KPL75_21705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KPL75_21715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KPL75_21720	COG0457	Tetratricopeptide repeat
KPL75_21725	COG5582	Belongs to the UPF0302 family
KPL75_21740	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KPL75_21750	COG4347	Protein of unknown function (DUF1405)
KPL75_21765	COG2738	Putative neutral zinc metallopeptidase
KPL75_21775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_21780	COG1694	Mazg nucleotide pyrophosphohydrolase
KPL75_21785	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KPL75_21790	COG1803	Methylglyoxal synthase
KPL75_21795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KPL75_21800	COG0438	transferase activity, transferring glycosyl groups
KPL75_21805	COG0617	tRNA 3'-terminal CCA addition
KPL75_21815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KPL75_21820	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KPL75_21830	COG1199	ATP-dependent helicase activity
KPL75_21830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KPL75_21850	COG3935	DnaD domain protein
KPL75_21855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KPL75_21865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_21865	COG4499	WXG100 protein secretion system (Wss), protein YukC
KPL75_21870	COG3331	DNA recombination
KPL75_21905	COG4474	Belongs to the UPF0398 family
KPL75_21910	COG3599	regulation of cell shape
KPL75_21920	COG0116	Belongs to the methyltransferase superfamily
KPL75_21930	COG1199	ATP-dependent helicase activity
KPL75_21935	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KPL75_21940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_21945	COG0024	Methionine aminopeptidase
KPL75_21955	COG2233	PERMEase
KPL75_21960	COG2311	Membrane
KPL75_21970	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KPL75_21980	COG0456	acetyltransferase
KPL75_22010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KPL75_22035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KPL75_22050	COG1215	transferase activity, transferring glycosyl groups
KPL75_22055	COG0438	transferase activity, transferring glycosyl groups
KPL75_22090	COG0328	RNA-DNA hybrid ribonuclease activity
KPL75_22125	COG3403	YqcI/YcgG family
KPL75_22130	COG1280	lysine exporter protein (LysE YggA)
KPL75_22145	COG3162	membrane
KPL75_22150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KPL75_22155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_22165	COG0475	glutathione-regulated potassium exporter activity
KPL75_22170	COG0789	Transcriptional regulator
KPL75_22170	COG4978	Transcriptional regulator
KPL75_22180	COG2323	membrane
KPL75_22185	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KPL75_22240	COG1923	regulation of RNA biosynthetic process
KPL75_22250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KPL75_22255	COG1360	Flagellar Motor Protein
KPL75_22260	COG2201	protein-glutamate methylesterase activity
KPL75_22265	COG2198	Histidine kinase
KPL75_22265	COG0643	Histidine kinase
KPL75_22270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_22270	COG1776	CheC inhibitor of MCP methylation
KPL75_22290	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KPL75_22310	COG1256	bacterial-type flagellum assembly
KPL75_22315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_22335	COG1815	bacterial-type flagellum-dependent cell motility
KPL75_22340	COG1558	bacterial-type flagellum-dependent cell motility
KPL75_22350	COG1766	The M ring may be actively involved in energy transduction
KPL75_22355	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_22365	COG1157	protein secretion by the type III secretion system
KPL75_22400	COG0784	Response regulator, receiver
KPL75_22400	COG0835	chemotaxis
KPL75_22420	COG0861	Integral membrane protein TerC family
KPL75_22430	COG3383	formate dehydrogenase (NAD+) activity
KPL75_22435	COG2427	Protein of unknown function (DUF1641)
KPL75_22440	COG5609	conserved protein (DUF2294)
KPL75_22445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KPL75_22455	COG2116	formate transmembrane transporter activity
KPL75_22460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_22465	COG0303	'Molybdopterin
KPL75_22470	COG0314	molybdopterin synthase activity
KPL75_22475	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KPL75_22485	COG0489	protein tyrosine kinase activity
KPL75_22490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_22495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_22500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_22505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KPL75_22510	COG0741	lytic transglycosylase activity
KPL75_22520	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_22525	COG1776	CheC inhibitor of MCP methylation
KPL75_22525	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KPL75_22535	COG1338	Plays a role in the flagellum-specific transport system
KPL75_22540	COG1987	bacterial-type flagellum assembly
KPL75_22550	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KPL75_22555	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KPL75_22560	COG1419	protein localization to endoplasmic reticulum
KPL75_22565	COG4786	Flagellar basal body rod
KPL75_22605	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_22640	COG0583	DNA-binding transcription factor activity
KPL75_22645	COG3842	ATPase activity
KPL75_22675	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_22710	COG1846	Transcriptional regulator
KPL75_22720	COG0367	asparagine synthase
KPL75_22760	COG1216	Glycosyl transferase, family 2
KPL75_22760	COG0438	transferase activity, transferring glycosyl groups
KPL75_22765	COG1757	Na H antiporter
KPL75_22795	COG0534	Mate efflux family protein
KPL75_22800	COG3340	Belongs to the peptidase S51 family
KPL75_22820	COG0785	Cytochrome C biogenesis protein
KPL75_22825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_22840	COG3048	D-serine ammonia-lyase activity
KPL75_22845	COG2733	membrane
KPL75_22880	COG1131	(ABC) transporter
KPL75_22900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_22905	COG2801	Transposase and inactivated derivatives
KPL75_22955	COG0528	UMP kinase activity
KPL75_22965	COG1027	Aspartate ammonia-lyase
KPL75_22970	COG0281	malic enzyme
KPL75_22975	COG4191	Histidine kinase
KPL75_22980	COG0784	Response regulator, receiver
KPL75_22985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KPL75_23040	COG2814	Major facilitator Superfamily
KPL75_23060	COG1695	Transcriptional regulator
KPL75_23070	COG0477	Major facilitator Superfamily
KPL75_23085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KPL75_23090	COG2223	nitrite transmembrane transporter activity
KPL75_23095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KPL75_23110	COG2244	polysaccharide biosynthetic process
KPL75_23115	COG0733	neurotransmitter:sodium symporter activity
KPL75_23120	COG5566	PFAM Mor transcription activator
KPL75_23125	COG2323	membrane
KPL75_23140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KPL75_23155	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KPL75_23180	COG2814	Major facilitator Superfamily
KPL75_23190	COG3384	dioxygenase
KPL75_23200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_23240	COG4166	transmembrane transport
KPL75_23250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_23270	COG1914	H( )-stimulated, divalent metal cation uptake system
KPL75_23275	COG1054	Belongs to the UPF0176 family
KPL75_23285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KPL75_23290	COG0531	amino acid
KPL75_23330	COG0745	RESPONSE REGULATOR receiver
KPL75_23335	COG5002	protein histidine kinase activity
KPL75_23360	COG2390	Transcriptional regulator
KPL75_23370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KPL75_23375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KPL75_23380	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KPL75_23395	COG4846	Membrane protein involved in cytochrome C biogenesis
KPL75_23415	COG0583	DNA-binding transcription factor activity
KPL75_23430	COG0006	proline dipeptidase activity
KPL75_23440	COG2132	Multicopper oxidase
KPL75_23450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KPL75_23460	COG0583	DNA-binding transcription factor activity
KPL75_23480	COG1114	Component of the transport system for branched-chain amino acids
KPL75_23490	COG4641	Protein conserved in bacteria
KPL75_23500	COG2372	response to copper ion
KPL75_23500	COG1276	copper resistance
KPL75_23505	COG4549	nuclear export factor GLE1
KPL75_23515	COG0697	spore germination
KPL75_23520	COG0583	DNA-binding transcription factor activity
KPL75_23525	COG1959	2 iron, 2 sulfur cluster binding
KPL75_23530	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KPL75_23535	COG0778	Nitroreductase
KPL75_23545	COG0628	permease
KPL75_23560	COG1231	oxidoreductase activity
KPL75_23565	COG0523	cobalamin synthesis protein
KPL75_23575	COG0411	ABC transporter
KPL75_23595	COG0583	DNA-binding transcription factor activity
KPL75_23605	COG1942	4-Oxalocrotonate Tautomerase
KPL75_23620	COG0346	lactoylglutathione lyase activity
KPL75_23630	COG1271	oxidase subunit
KPL75_23635	COG1294	oxidase, subunit
KPL75_23640	COG4988	ABC transporter
KPL75_23645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KPL75_23670	COG1619	proteins homologs of microcin C7 resistance protein MccF
KPL75_23675	COG1686	Belongs to the peptidase S11 family
KPL75_23690	COG1388	LysM domain
KPL75_23690	COG0791	NLP P60 protein
KPL75_23700	COG1132	(ABC) transporter
KPL75_23705	COG0745	RESPONSE REGULATOR receiver
KPL75_23710	COG5002	protein histidine kinase activity
KPL75_23715	COG0300	oxidoreductase activity
KPL75_23720	COG4122	O-methyltransferase activity
KPL75_23750	COG0460	homoserine dehydrogenase
KPL75_23760	COG0083	homoserine kinase activity
KPL75_23775	COG1316	TRANSCRIPTIONal
KPL75_23785	COG0745	RESPONSE REGULATOR receiver
KPL75_23790	COG5002	protein histidine kinase activity
KPL75_23805	COG1285	pathogenesis
KPL75_23810	COG1247	-acetyltransferase
KPL75_23830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KPL75_23840	COG1082	Xylose isomerase domain protein TIM barrel
KPL75_23850	COG2814	Major facilitator Superfamily
KPL75_23855	COG1279	arginine transmembrane transporter activity
KPL75_23860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_23870	COG1752	Esterase of the alpha-beta hydrolase superfamily
KPL75_23905	COG0577	efflux transmembrane transporter activity
KPL75_23910	COG2002	toxin-antitoxin pair type II binding
KPL75_23940	COG1404	Belongs to the peptidase S8 family
KPL75_23945	COG0640	Transcriptional regulator
KPL75_23950	COG0667	Aldo Keto reductase
KPL75_23955	COG2814	Major facilitator Superfamily
KPL75_23995	COG3949	Membrane
KPL75_24000	COG0783	Belongs to the Dps family
KPL75_24015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KPL75_24025	COG1231	oxidoreductase activity
KPL75_24035	COG4989	oxidoreductase activity
KPL75_24040	COG0523	cobalamin synthesis protein
KPL75_24055	COG0456	acetyltransferase
KPL75_24060	COG0803	Belongs to the bacterial solute-binding protein 9 family
KPL75_24075	COG1902	pentaerythritol trinitrate reductase activity
KPL75_24080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KPL75_24090	COG4166	transmembrane transport
KPL75_24095	COG0346	lactoylglutathione lyase activity
KPL75_24105	COG0406	alpha-ribazole phosphatase activity
KPL75_24115	COG5337	Spore coat protein CotH
KPL75_24120	COG1051	belongs to the nudix hydrolase family
KPL75_24125	COG0586	Pfam SNARE associated Golgi protein
KPL75_24130	COG2244	polysaccharide biosynthetic process
KPL75_24140	COG0701	Predicted permease
KPL75_24145	COG3689	TIGRFAM TIGR03943 family protein
KPL75_24150	COG1607	acyl-coa hydrolase
KPL75_24160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KPL75_24175	COG0702	epimerase
KPL75_24180	COG2839	Protein conserved in bacteria
KPL75_24185	COG1253	flavin adenine dinucleotide binding
KPL75_24210	COG1114	Component of the transport system for branched-chain amino acids
KPL75_24215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KPL75_24230	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_24240	COG1876	peptidase activity
KPL75_24255	COG2211	Major facilitator Superfamily
KPL75_24280	COG0561	phosphatase activity
KPL75_24290	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPL75_24305	COG1819	glycosyl
KPL75_24310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KPL75_24315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_24340	COG0456	acetyltransferase
KPL75_24375	COG4499	WXG100 protein secretion system (Wss), protein YukC
KPL75_24460	COG3874	Sporulation protein YtfJ
KPL75_24485	COG2226	methyltransferase
KPL75_24510	COG0346	lactoylglutathione lyase activity
KPL75_24520	COG0604	alcohol dehydrogenase
KPL75_24525	COG1595	DNA-templated transcription, initiation
KPL75_24545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KPL75_24545	COG0426	domain, Protein
KPL75_24555	COG0386	Belongs to the glutathione peroxidase family
KPL75_24560	COG1305	Transglutaminase-like
KPL75_24565	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
KPL75_24570	COG0714	Associated with various cellular activities
KPL75_24575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KPL75_24580	COG1140	nitrate reductase beta subunit
KPL75_24585	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
KPL75_24590	COG2181	nitrate reductase activity
KPL75_24595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KPL75_24600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KPL75_24605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KPL75_24610	COG0303	'Molybdopterin
KPL75_24615	COG0314	molybdopterin synthase activity
KPL75_24625	COG2223	nitrite transmembrane transporter activity
KPL75_24640	COG1648	precorrin-2 dehydrogenase activity
KPL75_24650	COG1587	Uroporphyrinogen-III synthase
KPL75_24650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KPL75_24655	COG2146	nitrite reductase [NAD(P)H] activity
KPL75_24660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KPL75_24665	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KPL75_24700	COG2359	stage V sporulation protein S
KPL75_24710	COG1418	mRNA catabolic process
KPL75_24715	COG0488	(ABC) transporter
KPL75_24730	COG0629	single-stranded DNA binding
KPL75_24755	COG1413	lyase activity
KPL75_24770	COG2136	Putative SAM-dependent methyltransferase
KPL75_24770	COG2521	methyltransferase
KPL75_24820	COG0017	Asparaginyl-tRNA synthetase
KPL75_24825	COG0733	neurotransmitter:sodium symporter activity
KPL75_24850	COG2610	gluconate transmembrane transporter activity
KPL75_24855	COG1454	alcohol dehydrogenase
KPL75_24860	COG1794	racemase activity, acting on amino acids and derivatives
KPL75_24870	COG0456	acetyltransferase
KPL75_24875	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KPL75_24885	COG1131	(ABC) transporter
KPL75_24890	COG4473	ABC transporter
KPL75_24900	COG0546	phosphoglycolate phosphatase activity
KPL75_24940	COG0768	penicillin binding
KPL75_24955	COG1272	protein, Hemolysin III
KPL75_24960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KPL75_24965	COG0805	protein transport
KPL75_24975	COG1307	EDD domain protein, DegV family
KPL75_24980	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KPL75_24985	COG1999	signal sequence binding
KPL75_24990	COG0071	Belongs to the small heat shock protein (HSP20) family
KPL75_24995	COG0367	asparagine synthase
KPL75_25010	COG0860	N-Acetylmuramoyl-L-alanine amidase
KPL75_25015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KPL75_25020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KPL75_25035	COG1335	isochorismatase
KPL75_25040	COG1051	belongs to the nudix hydrolase family
KPL75_25045	COG0668	transmembrane transport
KPL75_25050	COG2203	Gaf domain
KPL75_25050	COG4585	Histidine kinase
KPL75_25055	COG2197	response regulator
KPL75_25060	COG1737	Transcriptional regulator
KPL75_25065	COG1064	alcohol dehydrogenase
KPL75_25080	COG1070	Carbohydrate kinase
KPL75_25090	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KPL75_25125	COG1125	glycine betaine transport
KPL75_25125	COG0517	IMP dehydrogenase activity
KPL75_25130	COG1174	glycine betaine transport
KPL75_25165	COG1253	flavin adenine dinucleotide binding
KPL75_25170	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_25175	COG5506	Protein of unknown function (DUF1694)
KPL75_25190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KPL75_25195	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KPL75_25200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KPL75_25205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KPL75_25210	COG0456	acetyltransferase
KPL75_25215	COG3829	transcription factor binding
KPL75_25220	COG1509	lysine 2,3-aminomutase activity
KPL75_25230	COG4479	Belongs to the UPF0346 family
KPL75_25255	COG4991	sh3 domain protein
KPL75_25255	COG3064	Membrane
KPL75_25255	COG0515	serine threonine protein kinase
KPL75_25265	COG0671	phosphoesterase, PA-phosphatase related
KPL75_25270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KPL75_25280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KPL75_25285	COG0582	viral genome integration into host DNA
KPL75_25330	COG2801	Transposase and inactivated derivatives
KPL75_25355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KPL75_25375	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_25395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KPL75_25395	COG4499	WXG100 protein secretion system (Wss), protein YukC
KPL75_25405	COG2814	Major facilitator Superfamily
KPL75_25410	COG0372	Belongs to the citrate synthase family
KPL75_25415	COG2079	MmgE PrpD family protein
KPL75_25420	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KPL75_25425	COG1960	acyl-CoA dehydrogenase activity
KPL75_25430	COG2084	Dehydrogenase
KPL75_25435	COG1012	belongs to the aldehyde dehydrogenase family
KPL75_25440	COG1280	lysine exporter protein (LysE YggA)
KPL75_25445	COG1024	Enoyl-CoA hydratase
KPL75_25460	COG0420	3'-5' exonuclease activity
KPL75_25465	COG0419	ATPase involved in DNA repair
KPL75_25475	COG3397	chitin binding
KPL75_25480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KPL75_25495	COG2223	nitrite transmembrane transporter activity
KPL75_25500	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_25505	COG1169	isochorismate synthase
KPL75_25510	COG1021	2,3-dihydroxybenzoate-AMP ligase
KPL75_25515	COG1535	isochorismatase
KPL75_25515	COG3433	isochorismatase activity
KPL75_25520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KPL75_25525	COG3251	PFAM MbtH domain protein
KPL75_25530	COG2814	Major facilitator Superfamily
KPL75_25545	COG0776	regulation of translation
KPL75_25555	COG1115	amino acid carrier protein
KPL75_25575	COG2329	Antibiotic biosynthesis monooxygenase
KPL75_25580	COG1187	pseudouridine synthase activity
KPL75_25585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KPL75_25665	COG1136	(ABC) transporter
KPL75_25675	COG0596	Alpha beta hydrolase
KPL75_25680	COG2814	Major facilitator Superfamily
KPL75_25695	COG0028	Belongs to the TPP enzyme family
KPL75_25705	COG2226	methyltransferase
KPL75_25710	COG1253	flavin adenine dinucleotide binding
KPL75_25745	COG1846	Transcriptional regulator
KPL75_25755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KPL75_25760	COG1309	transcriptional regulator
KPL75_25790	COG1247	-acetyltransferase
KPL75_25825	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KPL75_25840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KPL75_25870	COG0561	phosphatase activity
KPL75_25880	COG0583	DNA-binding transcription factor activity
KPL75_25885	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KPL75_25905	COG0583	DNA-binding transcription factor activity
KPL75_25910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KPL75_25915	COG2258	MOSC domain
KPL75_25925	COG1132	(ABC) transporter
KPL75_25930	COG1132	(ABC) transporter
KPL75_25945	COG1396	sequence-specific DNA binding
KPL75_25980	COG1595	DNA-templated transcription, initiation
KPL75_26005	COG1649	PFAM Uncharacterised BCR, COG1649
KPL75_26030	COG2971	BadF BadG BcrA BcrD
KPL75_26050	COG1846	Transcriptional regulator
KPL75_26085	COG1309	transcriptional regulator
KPL75_26100	COG1136	(ABC) transporter
KPL75_26115	COG2226	methyltransferase
KPL75_26155	COG2195	Cleaves the N-terminal amino acid of tripeptides
KPL75_26175	COG1686	Belongs to the peptidase S11 family
KPL75_26205	COG1136	(ABC) transporter
KPL75_26210	COG0577	efflux transmembrane transporter activity
KPL75_26220	COG2205	protein histidine kinase activity
KPL75_26225	COG1136	(ABC) transporter
KPL75_26230	COG0577	efflux transmembrane transporter activity
KPL75_26240	COG0768	penicillin binding
KPL75_26245	COG1595	DNA-templated transcription, initiation
KPL75_26255	COG0768	penicillin binding
KPL75_26260	COG0768	penicillin binding
KPL75_26295	COG1316	TRANSCRIPTIONal
KPL75_26300	COG2239	Acts as a magnesium transporter
KPL75_26305	COG0772	Belongs to the SEDS family
KPL75_26315	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KPL75_26335	COG0697	spore germination
KPL75_26365	COG3397	chitin binding
KPL75_26380	COG1408	metallophosphoesterase
KPL75_26390	COG1131	(ABC) transporter
KPL75_26400	COG1309	transcriptional regulator
KPL75_26410	COG1960	acyl-CoA dehydrogenase activity
KPL75_26415	COG0439	Biotin carboxylase
KPL75_26420	COG0511	ligase activity, forming carbon-carbon bonds
KPL75_26425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KPL75_26430	COG1024	Enoyl-CoA hydratase
KPL75_26435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KPL75_26440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KPL75_26465	COG0572	uridine kinase
KPL75_26480	COG1686	Belongs to the peptidase S11 family
KPL75_26505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KPL75_26545	COG0577	efflux transmembrane transporter activity
KPL75_26545	COG1136	(ABC) transporter
KPL75_26555	COG0745	RESPONSE REGULATOR receiver
KPL75_26560	COG5002	protein histidine kinase activity
KPL75_26570	COG2207	Transcriptional regulator
KPL75_26600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KPL75_26620	COG0693	protein deglycase activity
KPL75_26640	COG0789	Transcriptional regulator
KPL75_26640	COG4978	Transcriptional regulator
KPL75_26650	COG1028	Short-chain dehydrogenase reductase Sdr
KPL75_26655	COG1733	regulation of RNA biosynthetic process
KPL75_26680	COG1309	transcriptional regulator
KPL75_26710	COG0697	spore germination
KPL75_26715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_26730	COG2368	4-hydroxyphenylacetate
KPL75_26745	COG1063	alcohol dehydrogenase
KPL75_26755	COG2323	membrane
KPL75_26770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_26775	COG0697	spore germination
KPL75_26795	COG0201	protein transport
KPL75_26825	COG1523	belongs to the glycosyl hydrolase 13 family
KPL75_26830	COG1073	alpha beta
KPL75_26855	COG0577	efflux transmembrane transporter activity
KPL75_26860	COG1136	(ABC) transporter
KPL75_26895	COG5002	protein histidine kinase activity
KPL75_26900	COG0745	RESPONSE REGULATOR receiver
KPL75_26905	COG1011	Hydrolase
KPL75_26930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KPL75_26935	COG1183	phosphatidylcholine synthase activity
KPL75_26940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KPL75_26950	COG1132	(ABC) transporter
KPL75_26960	COG3961	Belongs to the TPP enzyme family
KPL75_26980	COG0322	excinuclease ABC activity
KPL75_27005	COG2318	DinB family
KPL75_27020	COG4667	esterase of the alpha-beta hydrolase superfamily
KPL75_27040	COG3878	Protein conserved in bacteria
KPL75_27060	COG1051	belongs to the nudix hydrolase family
KPL75_27065	COG0592	DNA-directed DNA polymerase activity
KPL75_27075	COG2223	nitrite transmembrane transporter activity
KPL75_27085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KPL75_27110	COG0697	spore germination
KPL75_27115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KPL75_27135	COG0584	glycerophosphoryl diester phosphodiesterase
KPL75_27150	COG2814	Major facilitator Superfamily
KPL75_27195	COG0768	penicillin binding
KPL75_27200	COG0671	phosphoesterase, PA-phosphatase related
KPL75_27205	COG0604	alcohol dehydrogenase
KPL75_27210	COG5002	protein histidine kinase activity
KPL75_27215	COG0745	RESPONSE REGULATOR receiver
KPL75_27225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KPL75_27235	COG2205	protein histidine kinase activity
KPL75_27250	COG1122	ATPase activity
KPL75_27255	COG4720	Psort location CytoplasmicMembrane, score
KPL75_27260	COG1794	racemase activity, acting on amino acids and derivatives
KPL75_27265	COG1819	glycosyl
KPL75_27275	COG0768	penicillin binding
KPL75_27280	COG5002	protein histidine kinase activity