locus-tag	class	description
OXB_0001	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OXB_0003	COG1506	peptidase
OXB_0004	COG0494	nUDIX hydrolase
OXB_0007	COG0783	Belongs to the Dps family
OXB_0010	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OXB_0011	COG0596	Alpha beta hydrolase
OXB_0013	COG1169	isochorismate synthase
OXB_0014	COG1575	Belongs to the MenA family. Type 1 subfamily
OXB_0015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OXB_0018	COG1285	pathogenesis
OXB_0020	COG1979	alcohol dehydrogenase
OXB_0023	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OXB_0024	COG1012	belongs to the aldehyde dehydrogenase family
OXB_0025	COG3829	transcription factor binding
OXB_0026	COG1098	S1 RNA binding domain
OXB_0029	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OXB_0031	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OXB_0032	COG2814	Major facilitator Superfamily
OXB_0033	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OXB_0036	COG2111	Na H antiporter
OXB_0036	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OXB_0037	COG2111	Na H antiporter
OXB_0038	COG1006	Multisubunit Na H antiporter MnhC subunit
OXB_0039	COG0651	ATP synthesis coupled electron transport
OXB_0040	COG1863	multisubunit Na H antiporter MnhE subunit
OXB_0041	COG2212	antiporter activity
OXB_0042	COG1320	monovalent cation:proton antiporter activity
OXB_0047	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OXB_0049	COG1252	NADH dehydrogenase
OXB_0050	COG0316	Belongs to the HesB IscA family
OXB_0052	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OXB_0053	COG4837	Protein of unknown function (DUF1462)
OXB_0054	COG1252	NADH dehydrogenase
OXB_0056	COG0647	UMP catabolic process
OXB_0057	COG2445	Protein of unknown function DUF86
OXB_0058	COG4470	Protein conserved in bacteria
OXB_0059	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OXB_0061	COG0733	neurotransmitter:sodium symporter activity
OXB_0062	COG1757	Na H antiporter
OXB_0064	COG0737	Belongs to the 5'-nucleotidase family
OXB_0065	COG0730	response to heat
OXB_0066	COG1801	Protein of unknown function DUF72
OXB_0067	COG0719	Fe-S assembly protein
OXB_0068	COG0822	iron-sulfur transferase activity
OXB_0069	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OXB_0070	COG0719	Fe-S assembly protein
OXB_0071	COG0396	ATPase activity
OXB_0073	COG1464	Belongs to the NlpA lipoprotein family
OXB_0074	COG2011	ABC-type metal ion transport system permease component
OXB_0075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OXB_0076	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_0077	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OXB_0078	COG0509	glycine decarboxylation via glycine cleavage system
OXB_0079	COG1393	Belongs to the ArsC family
OXB_0080	COG1960	acyl-CoA dehydrogenase activity
OXB_0081	COG0183	Belongs to the thiolase family
OXB_0082	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_0082	COG1024	Enoyl-CoA hydratase
OXB_0083	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_0086	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_0087	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OXB_0091	COG1595	DNA-templated transcription, initiation
OXB_0093	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OXB_0094	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OXB_0095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OXB_0096	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OXB_0097	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OXB_0098	COG0640	Transcriptional regulator
OXB_0100	COG2271	Major facilitator Superfamily
OXB_0101	COG1473	amidohydrolase
OXB_0108	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_0110	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OXB_0111	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_0113	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_0115	COG0431	NADPH-dependent FMN reductase
OXB_0116	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_0118	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OXB_0121	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OXB_0131	COG5002	protein histidine kinase activity
OXB_0134	COG2311	Membrane
OXB_0137	COG2264	protein methyltransferase activity
OXB_0142	COG3177	Filamentation induced by cAMP protein fic
OXB_0144	COG0557	exoribonuclease II activity
OXB_0146	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OXB_0152	COG0126	phosphoglycerate kinase activity
OXB_0156	COG1704	LemA family
OXB_0158	COG0352	thiamine-phosphate diphosphorylase activity
OXB_0159	COG2104	thiamine diphosphate biosynthetic process
OXB_0160	COG2022	thiamine diphosphate biosynthetic process
OXB_0161	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OXB_0165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OXB_0167	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OXB_0169	COG1051	belongs to the nudix hydrolase family
OXB_0170	COG0492	ferredoxin-NADP+ reductase activity
OXB_0171	COG0457	Tetratricopeptide repeat
OXB_0172	COG0110	maltose O-acetyltransferase activity
OXB_0173	COG0546	phosphoglycolate phosphatase activity
OXB_0174	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OXB_0176	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OXB_0177	COG4372	Transposase
OXB_0180	COG3595	metallopeptidase activity
OXB_0181	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OXB_0182	COG0556	nucleotide-excision repair
OXB_0185	COG1131	(ABC) transporter
OXB_0190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OXB_0191	COG3481	metal-dependent phosphohydrolase, HD sub domain
OXB_0192	COG4717	serine-type aminopeptidase activity
OXB_0193	COG0420	3'-5' exonuclease activity
OXB_0194	COG1668	transmembrane transport
OXB_0195	COG4152	abc transporter atp-binding protein
OXB_0197	COG1476	TRANSCRIPTIONal
OXB_0199	COG1803	Methylglyoxal synthase
OXB_0200	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_0201	COG1024	Enoyl-CoA hydratase
OXB_0202	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OXB_0206	COG3871	stress protein (general stress protein 26)
OXB_0207	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OXB_0213	COG1253	flavin adenine dinucleotide binding
OXB_0214	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OXB_0215	COG3153	acetyltransferase
OXB_0215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OXB_0216	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OXB_0217	COG3118	belongs to the thioredoxin family
OXB_0218	COG0564	pseudouridine synthase activity
OXB_0220	COG2252	PERMEase
OXB_0222	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OXB_0223	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OXB_0224	COG3382	B3 4 domain protein
OXB_0232	COG0735	belongs to the Fur family
OXB_0234	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OXB_0236	COG4129	membrane
OXB_0239	COG0747	negative chemotaxis
OXB_0240	COG4608	Belongs to the ABC transporter superfamily
OXB_0241	COG0444	Belongs to the ABC transporter superfamily
OXB_0242	COG1132	(ABC) transporter
OXB_0243	COG3557	Belongs to the UPF0374 family
OXB_0246	COG1988	membrane-bound metal-dependent
OXB_0248	COG2137	regulation of response to DNA damage stimulus
OXB_0249	COG1090	epimerase
OXB_0255	COG2217	Heavy metal translocating P-type atpase
OXB_0256	COG1295	ribonuclease BN
OXB_0258	COG1115	amino acid carrier protein
OXB_0259	COG4840	Belongs to the UPF0435 family
OXB_0260	COG1360	Flagellar Motor Protein
OXB_0261	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OXB_0262	COG2309	aminopeptidase activity
OXB_0264	COG0288	reversible hydration of carbon dioxide
OXB_0265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OXB_0267	COG3859	Proton-coupled thiamine transporter YuaJ
OXB_0269	COG0024	Methionine aminopeptidase
OXB_0270	COG0513	Belongs to the DEAD box helicase family
OXB_0271	COG1794	racemase activity, acting on amino acids and derivatives
OXB_0274	COG0840	transmembrane signaling receptor activity
OXB_0275	COG0840	transmembrane signaling receptor activity
OXB_0276	COG0109	protoheme IX farnesyltransferase activity
OXB_0277	COG1126	abc transporter atp-binding protein
OXB_0278	COG0765	amino acid transport
OXB_0279	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_0280	COG0410	ABC transporter
OXB_0281	COG0683	leucine binding
OXB_0283	COG0559	Belongs to the binding-protein-dependent transport system permease family
OXB_0284	COG1022	Amp-dependent synthetase and ligase
OXB_0286	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_0287	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OXB_0289	COG1388	LysM domain
OXB_0289	COG3584	3D domain protein
OXB_0290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_0291	COG0840	transmembrane signaling receptor activity
OXB_0296	COG1115	amino acid carrier protein
OXB_0297	COG0346	lactoylglutathione lyase activity
OXB_0311	COG0071	Belongs to the small heat shock protein (HSP20) family
OXB_0312	COG4372	Transposase
OXB_0314	COG4372	Transposase
OXB_0315	COG3546	catalase activity
OXB_0318	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OXB_0320	COG1294	oxidase, subunit
OXB_0321	COG1271	oxidase subunit
OXB_0322	COG0494	nUDIX hydrolase
OXB_0323	COG1597	lipid kinase activity
OXB_0325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OXB_0326	COG0154	amidase activity
OXB_0327	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OXB_0328	COG4851	CamS sex pheromone cAM373 precursor
OXB_0330	COG0210	DNA helicase
OXB_0333	COG4496	protein, YerC YecD
OXB_0334	COG1470	cell adhesion involved in biofilm formation
OXB_0335	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OXB_0337	COG0697	spore germination
OXB_0341	COG0151	Belongs to the GarS family
OXB_0343	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OXB_0345	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OXB_0348	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OXB_0349	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OXB_0350	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OXB_0352	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OXB_0355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_0358	COG2252	PERMEase
OXB_0359	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OXB_0359	COG0519	Catalyzes the synthesis of GMP from XMP
OXB_0360	COG1305	Transglutaminase-like
OXB_0361	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OXB_0362	COG0714	Associated with various cellular activities
OXB_0364	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OXB_0365	COG0656	L-ascorbic acid biosynthetic process
OXB_0366	COG0626	cystathionine gamma-synthase activity
OXB_0367	COG0626	cystathionine gamma-synthase activity
OXB_0368	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OXB_0379	COG1556	Lactate utilization protein
OXB_0380	COG1139	Iron-sulfur cluster binding protein
OXB_0381	COG0247	lactate metabolic process
OXB_0384	COG0488	(ABC) transporter
OXB_0386	COG2814	Major facilitator Superfamily
OXB_0388	COG1846	Transcriptional regulator
OXB_0389	COG2046	Belongs to the sulfate adenylyltransferase family
OXB_0392	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OXB_0395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_0396	COG0039	L-malate dehydrogenase activity
OXB_0397	COG1012	belongs to the aldehyde dehydrogenase family
OXB_0399	COG0583	DNA-binding transcription factor activity
OXB_0400	COG1301	dicarboxylic acid transport
OXB_0402	COG2233	PERMEase
OXB_0406	COG1012	belongs to the aldehyde dehydrogenase family
OXB_0416	COG0450	alkyl hydroperoxide reductase
OXB_0420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OXB_0421	COG1522	sequence-specific DNA binding
OXB_0422	COG0010	Belongs to the arginase family
OXB_0427	COG0668	transmembrane transport
OXB_0429	COG1120	ATPase activity
OXB_0430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_0431	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_0432	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OXB_0433	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OXB_0436	COG2153	protein acetylation
OXB_0437	COG2226	methyltransferase
OXB_0439	COG1120	ATPase activity
OXB_0440	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_0441	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_0445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_0445	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_0447	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OXB_0449	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OXB_0450	COG1266	CAAX protease self-immunity
OXB_0451	COG1012	belongs to the aldehyde dehydrogenase family
OXB_0454	COG0805	protein transport
OXB_0455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OXB_0457	COG0488	(ABC) transporter
OXB_0458	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OXB_0459	COG0456	acetyltransferase
OXB_0460	COG1214	PFAM Peptidase M22, glycoprotease
OXB_0461	COG0802	atpase or kinase
OXB_0463	COG2183	response to ionizing radiation
OXB_0464	COG2208	phosphoserine phosphatase activity
OXB_0465	COG1191	sigma factor activity
OXB_0466	COG2172	sigma factor antagonist activity
OXB_0468	COG2208	phosphoserine phosphatase activity
OXB_0469	COG2172	sigma factor antagonist activity
OXB_0470	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_0471	COG1366	Belongs to the anti-sigma-factor antagonist family
OXB_0472	COG2337	Toxic component of a toxin-antitoxin (TA) module
OXB_0475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OXB_0476	COG0736	holo-[acyl-carrier-protein] synthase activity
OXB_0477	COG0705	Rhomboid family
OXB_0478	COG3428	Bacterial PH domain
OXB_0479	COG3402	PFAM membrane-flanked domain
OXB_0480	COG0513	Belongs to the DEAD box helicase family
OXB_0482	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OXB_0483	COG1181	Belongs to the D-alanine--D-alanine ligase family
OXB_0484	COG0772	Belongs to the SEDS family
OXB_0485	COG0772	Belongs to the SEDS family
OXB_0488	COG2814	Major facilitator Superfamily
OXB_0489	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OXB_0492	COG0706	membrane insertase activity
OXB_0496	COG0346	lactoylglutathione lyase activity
OXB_0498	COG2996	Protein conserved in bacteria
OXB_0504	COG0589	response to stress
OXB_0505	COG1320	monovalent cation:proton antiporter activity
OXB_0506	COG2212	antiporter activity
OXB_0507	COG1863	multisubunit Na H antiporter MnhE subunit
OXB_0508	COG0651	ATP synthesis coupled electron transport
OXB_0509	COG1006	Multisubunit Na H antiporter MnhC subunit
OXB_0511	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OXB_0511	COG2111	Na H antiporter
OXB_0514	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OXB_0515	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OXB_0516	COG0723	plastoquinol--plastocyanin reductase activity
OXB_0516	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OXB_0517	COG1227	inorganic diphosphatase activity
OXB_0518	COG1959	2 iron, 2 sulfur cluster binding
OXB_0521	COG0693	protein deglycase activity
OXB_0523	COG1132	(ABC) transporter
OXB_0525	COG0477	Major facilitator Superfamily
OXB_0528	COG4607	ABC-type enterochelin transport system periplasmic component
OXB_0529	COG4604	ABC transporter, ATP-binding protein
OXB_0530	COG4605	iron ion homeostasis
OXB_0531	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_0533	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OXB_0537	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OXB_0538	COG0590	tRNA wobble adenosine to inosine editing
OXB_0539	COG4876	unkown
OXB_0540	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_0543	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OXB_0544	COG1116	anion transmembrane transporter activity
OXB_0547	COG2824	Alkylphosphonate utilization operon protein PhnA
OXB_0548	COG1595	DNA-templated transcription, initiation
OXB_0554	COG1595	DNA-templated transcription, initiation
OXB_0558	COG2814	Major facilitator Superfamily
OXB_0559	COG2268	Band 7 protein
OXB_0560	COG1585	Membrane protein implicated in regulation of membrane protease activity
OXB_0561	COG1392	Phosphate transport regulator
OXB_0562	COG0306	phosphate transporter
OXB_0563	COG1278	Cold shock
OXB_0567	COG0500	methyltransferase
OXB_0569	COG1063	alcohol dehydrogenase
OXB_0570	COG2032	superoxide dismutase activity
OXB_0574	COG0456	acetyltransferase
OXB_0582	COG1131	(ABC) transporter
OXB_0586	COG1279	arginine transmembrane transporter activity
OXB_0587	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OXB_0588	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_0590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_0592	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_0593	COG0473	3-isopropylmalate dehydrogenase activity
OXB_0596	COG1024	Enoyl-CoA hydratase
OXB_0597	COG0183	Belongs to the thiolase family
OXB_0598	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_0599	COG1309	transcriptional regulator
OXB_0600	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_0601	COG1960	acyl-CoA dehydrogenase activity
OXB_0602	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_0604	COG0411	ABC transporter
OXB_0606	COG0559	Belongs to the binding-protein-dependent transport system permease family
OXB_0608	COG0789	Transcriptional regulator
OXB_0612	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OXB_0613	COG0393	Putative heavy-metal-binding
OXB_0614	COG1966	Carbon starvation protein
OXB_0616	COG3275	phosphorelay sensor kinase activity
OXB_0617	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OXB_0619	COG4895	conserved protein (DUF2196)
OXB_0621	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OXB_0622	COG0573	inorganic phosphate transmembrane transporter activity
OXB_0623	COG0581	inorganic phosphate transmembrane transporter activity
OXB_0624	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OXB_0625	COG5002	protein histidine kinase activity
OXB_0630	COG3706	GGDEF domain
OXB_0632	COG4856	YbbR-like protein
OXB_0633	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OXB_0634	COG5662	AntiSigma factor
OXB_0635	COG1595	DNA-templated transcription, initiation
OXB_0637	COG5001	Diguanylate cyclase
OXB_0640	COG2194	sulfuric ester hydrolase activity
OXB_0642	COG0489	protein tyrosine kinase activity
OXB_0643	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_0645	COG0662	Cupin 2, conserved barrel domain protein
OXB_0647	COG1304	FMN binding
OXB_0649	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_0650	COG0702	epimerase
OXB_0653	COG5504	Zn-dependent protease
OXB_0655	COG1802	Transcriptional regulator
OXB_0657	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_0658	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_0660	COG0277	FAD linked oxidase domain protein
OXB_0662	COG0542	response to heat
OXB_0664	COG2304	oxidoreductase activity
OXB_0665	COG2318	DinB family
OXB_0669	COG1131	(ABC) transporter
OXB_0670	COG1725	Transcriptional regulator
OXB_0671	COG1115	amino acid carrier protein
OXB_0672	COG2056	Na+-H+ antiporter family
OXB_0673	COG2056	Na+-H+ antiporter family
OXB_0675	COG2986	histidine ammonia-lyase
OXB_0676	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OXB_0677	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OXB_0678	COG0101	tRNA pseudouridine synthase activity
OXB_0679	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OXB_0680	COG1122	ATPase activity
OXB_0681	COG1122	ATPase activity
OXB_0683	COG0202	RNA polymerase activity
OXB_0686	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OXB_0688	COG0201	protein transport
OXB_0692	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OXB_0693	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OXB_0699	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OXB_0700	COG0255	Belongs to the universal ribosomal protein uL29 family
OXB_0701	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OXB_0702	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OXB_0705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OXB_0708	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OXB_0709	COG0051	transcription antitermination factor activity, RNA binding
OXB_0713	COG0049	tRNA binding
OXB_0715	COG1358	cellular component organization or biogenesis
OXB_0718	COG2813	Specifically methylates the guanine in position
OXB_0723	COG0250	Participates in transcription elongation, termination and antitermination
OXB_0724	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OXB_0726	COG3688	RNA-binding protein containing a PIN domain
OXB_0727	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OXB_0730	COG1045	serine acetyltransferase
OXB_0734	COG4956	integral membrane protein (PIN domain superfamily)
OXB_0735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OXB_0736	COG0542	response to heat
OXB_0737	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OXB_0738	COG3880	PFAM UvrB UvrC protein
OXB_0742	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OXB_0743	COG1268	BioY protein
OXB_0745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OXB_0745	COG0646	methionine synthase
OXB_0746	COG0646	methionine synthase
OXB_0746	COG1410	methionine synthase
OXB_0747	COG0415	Belongs to the DNA photolyase family
OXB_0748	COG0415	Belongs to the DNA photolyase family
OXB_0750	COG1136	(ABC) transporter
OXB_0752	COG3011	Protein conserved in bacteria
OXB_0754	COG1012	belongs to the aldehyde dehydrogenase family
OXB_0755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_0756	COG0745	RESPONSE REGULATOR receiver
OXB_0757	COG3850	Histidine kinase
OXB_0757	COG5002	protein histidine kinase activity
OXB_0758	COG3226	Transcriptional regulator
OXB_0760	COG0655	NAD(P)H dehydrogenase (quinone) activity
OXB_0761	COG0400	carboxylic ester hydrolase activity
OXB_0763	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OXB_0764	COG0351	phosphomethylpyrimidine kinase
OXB_0765	COG0352	thiamine-phosphate diphosphorylase activity
OXB_0768	COG2197	response regulator
OXB_0778	COG2197	response regulator
OXB_0779	COG4585	Histidine kinase
OXB_0780	COG3239	Fatty acid desaturase
OXB_0781	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_0782	COG3118	belongs to the thioredoxin family
OXB_0783	COG0671	phosphoesterase, PA-phosphatase related
OXB_0785	COG1970	mechanosensitive ion channel activity
OXB_0789	COG0390	transport system, permease component
OXB_0790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OXB_0791	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OXB_0792	COG1131	(ABC) transporter
OXB_0793	COG1131	(ABC) transporter
OXB_0794	COG1725	Transcriptional regulator
OXB_0799	COG4372	Transposase
OXB_0803	COG0697	spore germination
OXB_0806	COG0840	transmembrane signaling receptor activity
OXB_0807	COG1607	acyl-coa hydrolase
OXB_0808	COG0791	NLP P60 protein
OXB_0809	COG4948	Mandelate Racemase Muconate Lactonizing
OXB_0810	COG1619	proteins homologs of microcin C7 resistance protein MccF
OXB_0813	COG2746	aminoglycoside 3-N-acetyltransferase activity
OXB_0815	COG0133	tryptophan synthase activity
OXB_0816	COG0135	phosphoribosylanthranilate isomerase activity
OXB_0817	COG0134	indole-3-glycerol-phosphate synthase activity
OXB_0818	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OXB_0819	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OXB_0820	COG2508	Transcriptional regulator
OXB_0823	COG1473	amidohydrolase
OXB_0825	COG1187	pseudouridine synthase activity
OXB_0826	COG2239	Acts as a magnesium transporter
OXB_0827	COG0702	epimerase
OXB_0828	COG0427	acetyl-CoA hydrolase
OXB_0830	COG2270	Major facilitator Superfamily
OXB_0831	COG0183	Belongs to the thiolase family
OXB_0832	COG1960	acyl-CoA dehydrogenase activity
OXB_0834	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_0835	COG1024	Enoyl-CoA hydratase
OXB_0836	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_0837	COG2508	Transcriptional regulator
OXB_0838	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OXB_0840	COG0179	Fumarylacetoacetate (FAA) hydrolase
OXB_0842	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OXB_0844	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_0845	COG2211	Major facilitator Superfamily
OXB_0846	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OXB_0848	COG1414	Transcriptional regulator
OXB_0850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OXB_0857	COG0559	Belongs to the binding-protein-dependent transport system permease family
OXB_0859	COG2814	Major facilitator Superfamily
OXB_0861	COG2514	catechol 2,3-dioxygenase activity
OXB_0862	COG1733	regulation of RNA biosynthetic process
OXB_0866	COG1012	belongs to the aldehyde dehydrogenase family
OXB_0870	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_0872	COG0247	lactate metabolic process
OXB_0873	COG0277	FAD linked oxidase domain protein
OXB_0874	COG2186	Transcriptional regulator
OXB_0876	COG2233	PERMEase
OXB_0877	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OXB_0880	COG0583	DNA-binding transcription factor activity
OXB_0882	COG2304	oxidoreductase activity
OXB_0883	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
OXB_0886	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OXB_0887	COG1533	DNA photolyase activity
OXB_0889	COG1473	amidohydrolase
OXB_0891	COG2011	ABC-type metal ion transport system permease component
OXB_0892	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OXB_0895	COG0154	amidase activity
OXB_0897	COG0579	oxidoreductase
OXB_0903	COG3290	protein histidine kinase activity
OXB_0904	COG4565	transcriptional regulatory protein
OXB_0905	COG2851	Citrate transporter
OXB_0907	COG1114	Component of the transport system for branched-chain amino acids
OXB_0908	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_0911	COG0300	oxidoreductase activity
OXB_0918	COG0322	excinuclease ABC activity
OXB_0923	COG4372	Transposase
OXB_0930	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OXB_0939	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_0942	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OXB_0943	COG4853	Protein conserved in bacteria
OXB_0944	COG4863	YycH protein
OXB_0945	COG5002	protein histidine kinase activity
OXB_0946	COG0745	RESPONSE REGULATOR receiver
OXB_0947	COG0741	lytic transglycosylase activity
OXB_0947	COG1196	nuclear chromosome segregation
OXB_0947	COG0739	heme binding
OXB_0948	COG0305	Participates in initiation and elongation during chromosome replication
OXB_0950	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OXB_0952	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OXB_0953	COG0629	single-stranded DNA binding
OXB_0956	COG0012	GTP binding
OXB_0957	COG4481	Protein conserved in bacteria
OXB_0958	COG0668	transmembrane transport
OXB_0960	COG1811	Na channel or pump
OXB_0961	COG1475	DNA binding
OXB_0962	COG1192	Involved in chromosome partitioning
OXB_0967	COG1847	R3H domain protein
OXB_0968	COG0706	membrane insertase activity
OXB_0969	COG0594	ribonuclease P activity
OXB_0970	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OXB_0972	COG0592	DNA-directed DNA polymerase activity
OXB_0975	COG0187	DNA topoisomerase II activity
OXB_0976	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OXB_0981	COG0516	GMP reductase activity
OXB_0981	COG0517	IMP dehydrogenase activity
OXB_0983	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OXB_0984	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OXB_0985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OXB_0986	COG0590	tRNA wobble adenosine to inosine editing
OXB_0987	COG1428	Deoxynucleoside kinase
OXB_0988	COG1428	Deoxynucleoside kinase
OXB_0989	COG0527	aspartate kinase activity
OXB_0990	COG0460	homoserine dehydrogenase
OXB_0991	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OXB_0994	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OXB_0995	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OXB_1003	COG1982	Orn Lys Arg decarboxylase major
OXB_1004	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OXB_1005	COG3870	Protein conserved in bacteria
OXB_1006	COG1728	Protein conserved in bacteria
OXB_1007	COG0470	DNA polymerase III
OXB_1008	COG1774	PSP1 C-terminal conserved region
OXB_1009	COG4467	Involved in initiation control of chromosome replication
OXB_1010	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OXB_1012	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OXB_1013	COG2002	toxin-antitoxin pair type II binding
OXB_1015	COG0084	hydrolase, TatD family'
OXB_1016	COG3584	3D domain protein
OXB_1016	COG3583	domain protein
OXB_1019	COG4466	Protein conserved in bacteria
OXB_1021	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OXB_1022	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OXB_1023	COG0251	oxidation-reduction process
OXB_1024	COG2088	sporulation resulting in formation of a cellular spore
OXB_1025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OXB_1026	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OXB_1028	COG0193	aminoacyl-tRNA hydrolase activity
OXB_1030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OXB_1031	COG2002	toxin-antitoxin pair type II binding
OXB_1032	COG2244	polysaccharide biosynthetic process
OXB_1033	COG3956	TIGRFAM MazG family protein
OXB_1034	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OXB_1038	COG1098	S1 RNA binding domain
OXB_1039	COG2208	phosphoserine phosphatase activity
OXB_1040	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OXB_1040	COG0037	tRNA processing
OXB_1042	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OXB_1043	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OXB_1045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OXB_1046	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OXB_1047	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OXB_1048	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OXB_1049	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OXB_1050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OXB_1051	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OXB_1056	COG1295	ribonuclease BN
OXB_1058	COG5002	protein histidine kinase activity
OXB_1058	COG3850	Histidine kinase
OXB_1070	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OXB_1071	COG4841	protein insertion into membrane
OXB_1080	COG4149	molybdate abc transporter
OXB_1081	COG0725	ABC transporter, periplasmic molybdate-binding protein
OXB_1082	COG3842	ATPase activity
OXB_1083	COG4841	protein insertion into membrane
OXB_1086	COG0697	spore germination
OXB_1087	COG4682	membrane
OXB_1088	COG2112	serine threonine protein kinase
OXB_1089	COG2217	Heavy metal translocating P-type atpase
OXB_1090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OXB_1091	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OXB_1092	COG1522	sequence-specific DNA binding
OXB_1099	COG0640	Transcriptional regulator
OXB_1101	COG1937	Protein conserved in bacteria
OXB_1102	COG2608	mercury ion transmembrane transporter activity
OXB_1103	COG2217	Heavy metal translocating P-type atpase
OXB_1106	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OXB_1107	COG2814	Major facilitator Superfamily
OXB_1113	COG0745	RESPONSE REGULATOR receiver
OXB_1113	COG2972	Histidine kinase
OXB_1114	COG3300	MHYT domain
OXB_1114	COG5001	Diguanylate cyclase
OXB_1115	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OXB_1117	COG5298	Protein conserved in bacteria
OXB_1118	COG1215	transferase activity, transferring glycosyl groups
OXB_1121	COG1595	DNA-templated transcription, initiation
OXB_1123	COG0277	FAD linked oxidase domain protein
OXB_1131	COG0697	spore germination
OXB_1133	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OXB_1137	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_1139	COG0805	protein transport
OXB_1140	COG2814	Major facilitator Superfamily
OXB_1142	COG1346	cytolysis
OXB_1143	COG1380	Effector of murein hydrolase LrgA
OXB_1144	COG0628	permease
OXB_1145	COG1309	transcriptional regulator
OXB_1153	COG0427	acetyl-CoA hydrolase
OXB_1154	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_1155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_1156	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_1160	COG1960	acyl-CoA dehydrogenase activity
OXB_1161	COG1960	acyl-CoA dehydrogenase activity
OXB_1162	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OXB_1163	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_1164	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_1165	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_1166	COG1960	acyl-CoA dehydrogenase activity
OXB_1167	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_1168	COG1024	Enoyl-CoA hydratase
OXB_1169	COG0697	spore germination
OXB_1170	COG2195	Cleaves the N-terminal amino acid of tripeptides
OXB_1171	COG0583	DNA-binding transcription factor activity
OXB_1172	COG2855	membrane
OXB_1174	COG1937	Protein conserved in bacteria
OXB_1175	COG2210	Belongs to the sulfur carrier protein TusA family
OXB_1177	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_1177	COG0425	Belongs to the sulfur carrier protein TusA family
OXB_1178	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_1178	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_1179	COG0425	Belongs to the sulfur carrier protein TusA family
OXB_1180	COG0730	response to heat
OXB_1181	COG2814	Major facilitator Superfamily
OXB_1182	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OXB_1184	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OXB_1185	COG0559	Belongs to the binding-protein-dependent transport system permease family
OXB_1186	COG0559	Belongs to the binding-protein-dependent transport system permease family
OXB_1191	COG0492	ferredoxin-NADP+ reductase activity
OXB_1192	COG1141	Ferredoxin
OXB_1193	COG3396	Phenylacetate-CoA oxygenase
OXB_1199	COG1024	Enoyl-CoA hydratase
OXB_1201	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_1202	COG0183	Belongs to the thiolase family
OXB_1203	COG1024	Enoyl-CoA hydratase
OXB_1204	COG3327	negative regulation of DNA-templated transcription, initiation
OXB_1207	COG0840	transmembrane signaling receptor activity
OXB_1208	COG0386	Belongs to the glutathione peroxidase family
OXB_1209	COG0166	Belongs to the GPI family
OXB_1211	COG2258	MOSC domain
OXB_1212	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OXB_1213	COG0431	NADPH-dependent FMN reductase
OXB_1214	COG0697	spore germination
OXB_1219	COG0784	Response regulator, receiver
OXB_1219	COG2198	Histidine kinase
OXB_1219	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_1219	COG2205	protein histidine kinase activity
OXB_1228	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
OXB_1233	COG1120	ATPase activity
OXB_1234	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_1238	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_1239	COG1120	ATPase activity
OXB_1240	COG0357	Ribosomal RNA small subunit methyltransferase G
OXB_1242	COG2234	aminopeptidase activity
OXB_1243	COG2197	response regulator
OXB_1248	COG0183	Belongs to the thiolase family
OXB_1251	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_1254	COG0586	Pfam SNARE associated Golgi protein
OXB_1255	COG1968	undecaprenyl-diphosphatase activity
OXB_1256	COG1234	tRNA 3'-trailer cleavage
OXB_1258	COG0745	RESPONSE REGULATOR receiver
OXB_1259	COG5002	protein histidine kinase activity
OXB_1259	COG3850	Histidine kinase
OXB_1261	COG0840	transmembrane signaling receptor activity
OXB_1265	COG3279	Response regulator of the LytR AlgR family
OXB_1266	COG1732	Glycine betaine
OXB_1267	COG1174	glycine betaine transport
OXB_1268	COG1125	glycine betaine transport
OXB_1268	COG0517	IMP dehydrogenase activity
OXB_1269	COG0745	RESPONSE REGULATOR receiver
OXB_1270	COG2205	protein histidine kinase activity
OXB_1271	COG1136	(ABC) transporter
OXB_1272	COG0577	efflux transmembrane transporter activity
OXB_1273	COG1573	uracil-dna glycosylase
OXB_1276	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OXB_1277	COG1140	nitrate reductase beta subunit
OXB_1279	COG2181	nitrate reductase activity
OXB_1281	COG4585	Histidine kinase
OXB_1282	COG2197	response regulator
OXB_1284	COG2223	nitrite transmembrane transporter activity
OXB_1285	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OXB_1287	COG0315	cyclic pyranopterin monophosphate synthase activity
OXB_1290	COG0314	molybdopterin synthase activity
OXB_1292	COG0746	molybdenum cofactor guanylyltransferase activity
OXB_1293	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OXB_1296	COG3192	ethanolamine utilization protein
OXB_1297	COG4810	utilization protein
OXB_1298	COG4917	ethanolamine utilization protein
OXB_1299	COG4819	ethanolamine utilization protein
OXB_1300	COG4303	Ethanolamine ammonia lyase large subunit
OXB_1301	COG4302	ethanolamine ammonia-lyase activity
OXB_1302	COG4816	utilization protein
OXB_1303	COG1012	belongs to the aldehyde dehydrogenase family
OXB_1303	COG1454	alcohol dehydrogenase
OXB_1304	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
OXB_1306	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
OXB_1307	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
OXB_1308	COG0039	L-malate dehydrogenase activity
OXB_1313	COG1405	negative regulation of cell septum assembly
OXB_1313	COG3012	SEC-C Motif Domain Protein
OXB_1315	COG1309	transcriptional regulator
OXB_1316	COG2814	Major facilitator Superfamily
OXB_1317	COG1405	negative regulation of cell septum assembly
OXB_1317	COG3012	SEC-C Motif Domain Protein
OXB_1318	COG1012	belongs to the aldehyde dehydrogenase family
OXB_1320	COG1960	acyl-CoA dehydrogenase activity
OXB_1321	COG0583	DNA-binding transcription factor activity
OXB_1325	COG1914	H( )-stimulated, divalent metal cation uptake system
OXB_1327	COG0010	Belongs to the arginase family
OXB_1328	COG0436	Aminotransferase
OXB_1329	COG1309	transcriptional regulator
OXB_1330	COG1511	domain protein
OXB_1331	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_1332	COG0471	metal ion transport
OXB_1334	COG2966	Psort location CytoplasmicMembrane, score
OXB_1335	COG3610	response to peptide
OXB_1336	COG2200	EAL domain
OXB_1336	COG2199	diguanylate cyclase activity
OXB_1336	COG2202	Pas domain
OXB_1337	COG0697	spore germination
OXB_1340	COG1131	(ABC) transporter
OXB_1341	COG1725	Transcriptional regulator
OXB_1342	COG1132	(ABC) transporter
OXB_1343	COG1132	(ABC) transporter
OXB_1346	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OXB_1350	COG1307	EDD domain protein, DegV family
OXB_1352	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OXB_1353	COG4536	flavin adenine dinucleotide binding
OXB_1359	COG0431	NADPH-dependent FMN reductase
OXB_1360	COG0551	DNA topoisomerase type I activity
OXB_1360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OXB_1362	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OXB_1363	COG2364	Membrane
OXB_1367	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OXB_1373	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OXB_1375	COG2363	Small membrane protein
OXB_1379	COG0280	phosphate acetyltransferase
OXB_1383	COG1078	dGTPase activity
OXB_1384	COG3465	dGTPase activity
OXB_1388	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OXB_1392	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OXB_1394	COG1492	cobalamin metabolic process
OXB_1395	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
OXB_1398	COG2096	Adenosyltransferase
OXB_1399	COG0247	lactate metabolic process
OXB_1399	COG2181	nitrate reductase activity
OXB_1400	COG0183	Belongs to the thiolase family
OXB_1401	COG1250	3-hydroxyacyl-CoA dehydrogenase
OXB_1402	COG1960	acyl-CoA dehydrogenase activity
OXB_1403	COG1960	acyl-CoA dehydrogenase activity
OXB_1404	COG3226	Transcriptional regulator
OXB_1405	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_1405	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_1405	COG1703	isobutyryl-CoA mutase activity
OXB_1408	COG0504	CTP synthase activity
OXB_1410	COG4821	SIS domain
OXB_1411	COG4585	Histidine kinase
OXB_1412	COG2197	response regulator
OXB_1413	COG2204	response regulator
OXB_1414	COG0191	fructose-bisphosphate aldolase activity
OXB_1416	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OXB_1417	COG1494	fructose-1,6-bisphosphatase
OXB_1418	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OXB_1419	COG0254	rRNA binding
OXB_1421	COG1435	thymidine kinase activity
OXB_1423	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OXB_1426	COG0009	L-threonylcarbamoyladenylate synthase
OXB_1429	COG0840	transmembrane signaling receptor activity
OXB_1430	COG0698	ribose 5-phosphate isomerase
OXB_1431	COG4475	Protein of unknown function (DUF436)
OXB_1434	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OXB_1435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OXB_1437	COG0356	it plays a direct role in the translocation of protons across the membrane
OXB_1438	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OXB_1440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OXB_1443	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OXB_1445	COG4836	Membrane
OXB_1448	COG2385	sporulation resulting in formation of a cellular spore
OXB_1450	COG1609	Transcriptional regulator
OXB_1451	COG1077	Cell shape determining protein MreB Mrl
OXB_1452	COG4786	Flagellar basal body rod
OXB_1453	COG4786	Flagellar basal body rod
OXB_1462	COG0629	single-stranded DNA binding
OXB_1465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OXB_1467	COG1396	sequence-specific DNA binding
OXB_1474	COG2076	Multidrug Resistance protein
OXB_1478	COG2340	Cysteine-rich secretory protein family
OXB_1479	COG0793	Belongs to the peptidase S41A family
OXB_1479	COG3409	Peptidoglycan-binding domain 1 protein
OXB_1500	COG4372	Transposase
OXB_1502	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OXB_1503	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OXB_1505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OXB_1506	COG1228	amidohydrolase
OXB_1508	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OXB_1510	COG1309	transcriptional regulator
OXB_1511	COG1309	transcriptional regulator
OXB_1515	COG2267	carboxylic ester hydrolase activity
OXB_1517	COG0747	negative chemotaxis
OXB_1518	COG0606	chelatase, subunit chli
OXB_1520	COG3275	phosphorelay sensor kinase activity
OXB_1521	COG4753	response regulator
OXB_1521	COG2207	Transcriptional regulator
OXB_1523	COG0601	transmembrane transport
OXB_1525	COG0444	Belongs to the ABC transporter superfamily
OXB_1526	COG4608	Belongs to the ABC transporter superfamily
OXB_1539	COG2113	Glycine betaine
OXB_1548	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OXB_1549	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_1552	COG1228	amidohydrolase
OXB_1556	COG0444	Belongs to the ABC transporter superfamily
OXB_1557	COG4608	Belongs to the ABC transporter superfamily
OXB_1562	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_1563	COG1733	regulation of RNA biosynthetic process
OXB_1570	COG0069	glutamate synthase activity
OXB_1572	COG1953	Uracil, thiamine, allantoin
OXB_1574	COG0788	formyltetrahydrofolate deformylase activity
OXB_1576	COG0840	transmembrane signaling receptor activity
OXB_1577	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
OXB_1579	COG1120	ATPase activity
OXB_1580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_1581	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OXB_1586	COG5263	repeat protein
OXB_1586	COG4193	domain, Protein
OXB_1595	COG0726	polysaccharide deacetylase
OXB_1597	COG0196	riboflavin kinase activity
OXB_1598	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OXB_1601	COG1473	amidohydrolase
OXB_1603	COG4948	Mandelate Racemase Muconate Lactonizing
OXB_1604	COG1737	Transcriptional regulator
OXB_1606	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OXB_1608	COG4948	Mandelate Racemase Muconate Lactonizing
OXB_1609	COG3949	Membrane
OXB_1612	COG0129	dihydroxy-acid dehydratase activity
OXB_1613	COG0028	Belongs to the TPP enzyme family
OXB_1614	COG0440	acetolactate synthase activity
OXB_1619	COG0066	3-isopropylmalate dehydratase activity
OXB_1629	COG3279	Response regulator of the LytR AlgR family
OXB_1630	COG2224	Isocitrate lyase
OXB_1633	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_1634	COG0791	NLP P60 protein
OXB_1635	COG0438	transferase activity, transferring glycosyl groups
OXB_1635	COG0297	glycogen (starch) synthase activity
OXB_1637	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OXB_1638	COG0659	secondary active sulfate transmembrane transporter activity
OXB_1639	COG0791	NLP P60 protein
OXB_1639	COG1388	LysM domain
OXB_1640	COG1114	Component of the transport system for branched-chain amino acids
OXB_1641	COG5001	Diguanylate cyclase
OXB_1641	COG1716	ATPase activity
OXB_1642	COG0281	malic enzyme
OXB_1643	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OXB_1644	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OXB_1646	COG0363	glucosamine-6-phosphate deaminase activity
OXB_1647	COG0791	NLP P60 protein
OXB_1650	COG0653	protein targeting
OXB_1651	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OXB_1652	COG1316	TRANSCRIPTIONal
OXB_1653	COG1739	Uncharacterized protein family UPF0029
OXB_1654	COG4585	Histidine kinase
OXB_1655	COG2197	response regulator
OXB_1659	COG1473	amidohydrolase
OXB_1660	COG2329	Antibiotic biosynthesis monooxygenase
OXB_1661	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OXB_1666	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_1667	COG0095	Lipoate-protein ligase
OXB_1668	COG0745	RESPONSE REGULATOR receiver
OXB_1669	COG2205	protein histidine kinase activity
OXB_1670	COG1136	(ABC) transporter
OXB_1671	COG0577	efflux transmembrane transporter activity
OXB_1672	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_1675	COG1131	(ABC) transporter
OXB_1680	COG0823	Involved in the tonB-independent uptake of proteins
OXB_1680	COG1506	peptidase
OXB_1680	COG4946	Tricorn protease homolog
OXB_1683	COG1131	(ABC) transporter
OXB_1684	COG1511	domain protein
OXB_1684	COG0842	Transport permease protein
OXB_1685	COG1309	transcriptional regulator
OXB_1686	COG1027	Aspartate ammonia-lyase
OXB_1688	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_1690	COG1024	Enoyl-CoA hydratase
OXB_1691	COG1307	EDD domain protein, DegV family
OXB_1692	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OXB_1697	COG2747	anti-sigma28 factor FlgM
OXB_1698	COG3418	PFAM FlgN family protein
OXB_1699	COG1256	bacterial-type flagellum assembly
OXB_1699	COG4786	Flagellar basal body rod
OXB_1700	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_1704	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OXB_1705	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OXB_1706	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OXB_1718	COG0179	Fumarylacetoacetate (FAA) hydrolase
OXB_1719	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OXB_1732	COG1610	YqeY-like protein
OXB_1736	COG0840	transmembrane signaling receptor activity
OXB_1738	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OXB_1739	COG1516	flagellar protein fliS
OXB_1744	COG0653	protein targeting
OXB_1745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OXB_1748	COG2010	Cytochrome c
OXB_1749	COG2884	Cell division ATP-binding protein ftsE
OXB_1750	COG2177	Part of the ABC transporter FtsEX involved in
OXB_1751	COG0739	heme binding
OXB_1753	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_1754	COG0793	Belongs to the peptidase S41A family
OXB_1754	COG3409	Peptidoglycan-binding domain 1 protein
OXB_1756	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OXB_1758	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_1759	COG1349	DNA-binding transcription factor activity
OXB_1760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OXB_1761	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OXB_1762	COG0531	amino acid
OXB_1763	COG0546	phosphoglycolate phosphatase activity
OXB_1766	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
OXB_1767	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
OXB_1768	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
OXB_1769	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
OXB_1770	COG0039	L-malate dehydrogenase activity
OXB_1772	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OXB_1773	COG0398	Pfam SNARE associated Golgi protein
OXB_1776	COG1695	Transcriptional regulator
OXB_1784	COG2311	Membrane
OXB_1785	COG0179	Fumarylacetoacetate (FAA) hydrolase
OXB_1787	COG0366	Alpha amylase catalytic
OXB_1787	COG1874	Beta-galactosidase
OXB_1788	COG0446	pyridine nucleotide-disulphide oxidoreductase
OXB_1789	COG1307	EDD domain protein, DegV family
OXB_1790	COG0561	phosphatase activity
OXB_1791	COG1073	alpha beta
OXB_1792	COG2151	metal-sulfur cluster biosynthetic enzyme
OXB_1795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OXB_1798	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OXB_1799	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OXB_1802	COG0180	Tryptophanyl-tRNA synthetase
OXB_1805	COG4166	transmembrane transport
OXB_1806	COG0601	transmembrane transport
OXB_1807	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OXB_1808	COG0444	Belongs to the ABC transporter superfamily
OXB_1809	COG4608	Belongs to the ABC transporter superfamily
OXB_1811	COG1393	Belongs to the ArsC family
OXB_1812	COG4862	establishment of competence for transformation
OXB_1814	COG1164	Oligoendopeptidase f
OXB_1817	COG2346	COG2346, Truncated hemoglobins
OXB_1818	COG0741	lytic transglycosylase activity
OXB_1818	COG0739	heme binding
OXB_1818	COG1196	nuclear chromosome segregation
OXB_1820	COG2357	RelA SpoT domain protein
OXB_1822	COG0564	pseudouridine synthase activity
OXB_1823	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OXB_1824	COG2239	Acts as a magnesium transporter
OXB_1829	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OXB_1834	COG2153	protein acetylation
OXB_1836	COG2382	esterase
OXB_1837	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OXB_1838	COG1126	abc transporter atp-binding protein
OXB_1839	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_1840	COG0765	amino acid transport
OXB_1841	COG0765	amino acid transport
OXB_1843	COG1024	Enoyl-CoA hydratase
OXB_1844	COG0697	spore germination
OXB_1845	COG0697	spore germination
OXB_1850	COG4172	Belongs to the ABC transporter superfamily
OXB_1853	COG0477	Major facilitator Superfamily
OXB_1854	COG0753	catalase activity
OXB_1856	COG1012	belongs to the aldehyde dehydrogenase family
OXB_1857	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OXB_1859	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OXB_1862	COG0861	Integral membrane protein TerC family
OXB_1863	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OXB_1865	COG5002	protein histidine kinase activity
OXB_1866	COG1846	Transcriptional regulator
OXB_1869	COG4873	Protein conserved in bacteria
OXB_1871	COG2084	Dehydrogenase
OXB_1873	COG5001	Diguanylate cyclase
OXB_1873	COG3300	MHYT domain
OXB_1874	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_1876	COG0517	IMP dehydrogenase activity
OXB_1877	COG0477	Major facilitator Superfamily
OXB_1878	COG0583	DNA-binding transcription factor activity
OXB_1880	COG1131	(ABC) transporter
OXB_1883	COG0714	Associated with various cellular activities
OXB_1887	COG2814	Major facilitator Superfamily
OXB_1888	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OXB_1889	COG1177	transmembrane transport
OXB_1890	COG1176	ABC-type spermidine putrescine transport system, permease component I
OXB_1891	COG3842	ATPase activity
OXB_1895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_1896	COG0569	domain protein
OXB_1899	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_1904	COG0022	dehydrogenase e1 component
OXB_1905	COG0508	dehydrogenase complex catalyzes the overall conversion of
OXB_1910	COG0483	inositol monophosphate 1-phosphatase activity
OXB_1914	COG4896	Protein conserved in bacteria
OXB_1915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OXB_1917	COG0772	Belongs to the SEDS family
OXB_1918	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OXB_1925	COG3336	cytochrome c oxidase
OXB_1926	COG2322	membrane
OXB_1930	COG0527	aspartate kinase activity
OXB_1931	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OXB_1932	COG3679	Belongs to the UPF0342 family
OXB_1933	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_1937	COG0742	ribosomal rna small subunit methyltransferase
OXB_1938	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OXB_1940	COG3480	Lon protease (S16) C-terminal proteolytic domain
OXB_1943	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OXB_1944	COG1024	Enoyl-CoA hydratase
OXB_1945	COG0439	Biotin carboxylase
OXB_1946	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OXB_1947	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OXB_1948	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OXB_1951	COG2001	Belongs to the MraZ family
OXB_1953	COG4839	cell division protein FtsL
OXB_1955	COG0768	penicillin binding
OXB_1956	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OXB_1957	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OXB_1958	COG0772	Belongs to the SEDS family
OXB_1959	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OXB_1960	COG3879	Bacterial protein of unknown function (DUF881)
OXB_1961	COG3879	Bacterial protein of unknown function (DUF881)
OXB_1962	COG3856	small basic protein
OXB_1963	COG0849	cell division
OXB_1964	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OXB_1966	COG1191	sigma factor activity
OXB_1967	COG1191	sigma factor activity
OXB_1969	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OXB_1971	COG0762	integral membrane protein
OXB_1972	COG2302	S4 RNA-binding domain
OXB_1973	COG3599	regulation of cell shape
OXB_1975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OXB_1976	COG0564	pseudouridine synthase activity
OXB_1977	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OXB_1979	COG0540	Belongs to the ATCase OTCase family
OXB_1981	COG0505	Belongs to the CarA family
OXB_1984	COG0167	dihydroorotate dehydrogenase activity
OXB_1986	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OXB_1991	COG0194	GDP metabolic process
OXB_1993	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OXB_1994	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OXB_1995	COG0242	peptide deformylase activity
OXB_1997	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OXB_1997	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OXB_1998	COG0631	protein serine/threonine phosphatase activity
OXB_1999	COG2815	serine threonine protein kinase
OXB_1999	COG0515	serine threonine protein kinase
OXB_2000	COG1162	GTPase activity
OXB_2001	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OXB_2003	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OXB_2004	COG1302	Protein conserved in bacteria
OXB_2005	COG1461	Dihydroxyacetone kinase
OXB_2006	COG1760	l-serine dehydratase
OXB_2007	COG1760	l-serine dehydratase
OXB_2008	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OXB_2009	COG2050	protein possibly involved in aromatic compounds catabolism
OXB_2009	COG1349	DNA-binding transcription factor activity
OXB_2010	COG0416	fatty acid biosynthetic process
OXB_2011	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OXB_2012	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_2013	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OXB_2014	COG0571	ribonuclease III activity
OXB_2015	COG1196	nuclear chromosome segregation
OXB_2016	COG0552	protein localization to endoplasmic reticulum
OXB_2018	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OXB_2019	COG0228	four-way junction DNA binding
OXB_2020	COG1837	Belongs to the UPF0109 family
OXB_2021	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OXB_2023	COG0335	large ribosomal subunit rRNA binding
OXB_2025	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OXB_2026	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OXB_2028	COG2257	FlhB HrpN YscU SpaS Family
OXB_2029	COG0045	succinate-CoA ligase (ADP-forming) activity
OXB_2030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OXB_2031	COG0758	DNA mediated transformation
OXB_2032	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OXB_2034	COG4974	Belongs to the 'phage' integrase family
OXB_2036	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OXB_2037	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OXB_2039	COG1815	bacterial-type flagellum-dependent cell motility
OXB_2040	COG1558	bacterial-type flagellum-dependent cell motility
OXB_2041	COG1677	Flagellar hook-basal body complex protein FliE
OXB_2042	COG1766	The M ring may be actively involved in energy transduction
OXB_2043	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OXB_2045	COG1157	protein secretion by the type III secretion system
OXB_2046	COG2882	bacterial-type flagellum organization
OXB_2049	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OXB_2051	COG4786	Flagellar basal body rod
OXB_2052	COG1582	Flagellar protein (FlbD)
OXB_2053	COG1580	Controls the rotational direction of flagella during chemotaxis
OXB_2054	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OXB_2055	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OXB_2055	COG1776	CheC inhibitor of MCP methylation
OXB_2056	COG2201	protein-glutamate methylesterase activity
OXB_2057	COG3190	flagellar
OXB_2058	COG1338	Plays a role in the flagellum-specific transport system
OXB_2059	COG1987	bacterial-type flagellum assembly
OXB_2060	COG1684	flagellar biosynthetic protein fliR
OXB_2061	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OXB_2063	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OXB_2064	COG1419	protein localization to endoplasmic reticulum
OXB_2065	COG0455	bacterial-type flagellum organization
OXB_2066	COG2201	protein-glutamate methylesterase activity
OXB_2067	COG2198	Histidine kinase
OXB_2067	COG0643	Histidine kinase
OXB_2068	COG0835	chemotaxis
OXB_2069	COG1776	CheC inhibitor of MCP methylation
OXB_2070	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OXB_2071	COG1191	sigma factor activity
OXB_2076	COG0528	UMP kinase activity
OXB_2077	COG0233	cytoplasmic translational termination
OXB_2078	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OXB_2079	COG4589	Belongs to the CDS family
OXB_2081	COG0750	zinc metalloprotease
OXB_2083	COG2176	DNA-directed DNA polymerase activity
OXB_2085	COG0195	Participates in both transcription termination and antitermination
OXB_2086	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OXB_2087	COG1358	cellular component organization or biogenesis
OXB_2091	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OXB_2093	COG0196	riboflavin kinase activity
OXB_2094	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OXB_2095	COG0561	phosphatase activity
OXB_2097	COG0612	Peptidase, M16
OXB_2100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OXB_2101	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OXB_2103	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OXB_2104	COG1674	ftsk spoiiie
OXB_2105	COG2188	Transcriptional regulator
OXB_2110	COG0612	Peptidase, M16
OXB_2111	COG0612	Peptidase, M16
OXB_2112	COG0300	oxidoreductase activity
OXB_2114	COG1426	Protein conserved in bacteria
OXB_2115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OXB_2117	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OXB_2119	COG1692	metallophosphoesterase
OXB_2120	COG2359	stage V sporulation protein S
OXB_2121	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_2122	COG4550	Control of competence regulator ComK, YlbF/YmcA
OXB_2125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OXB_2126	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OXB_2130	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OXB_2133	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OXB_2144	COG1073	alpha beta
OXB_2145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OXB_2150	COG0596	Alpha beta hydrolase
OXB_2154	COG0697	spore germination
OXB_2155	COG1414	Transcriptional regulator
OXB_2157	COG1984	allophanate hydrolase subunit 2
OXB_2158	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OXB_2159	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OXB_2160	COG1914	H( )-stimulated, divalent metal cation uptake system
OXB_2162	COG4336	lyase activity
OXB_2163	COG0840	transmembrane signaling receptor activity
OXB_2164	COG2155	Conserved Protein
OXB_2165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_2170	COG0387	Pfam Sodium calcium exchanger
OXB_2178	COG2323	membrane
OXB_2179	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_2180	COG0840	transmembrane signaling receptor activity
OXB_2185	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OXB_2186	COG1653	transport
OXB_2188	COG0395	ABC-type sugar transport system, permease component
OXB_2190	COG3842	ATPase activity
OXB_2191	COG0647	UMP catabolic process
OXB_2194	COG0840	transmembrane signaling receptor activity
OXB_2197	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OXB_2199	COG1011	Hydrolase
OXB_2207	COG3773	Cell wall hydrolase
OXB_2208	COG0786	glutamate:sodium symporter activity
OXB_2210	COG0583	DNA-binding transcription factor activity
OXB_2211	COG2766	serine protein kinase
OXB_2212	COG2718	Belongs to the UPF0229 family
OXB_2213	COG2719	SpoVR family
OXB_2215	COG0488	(ABC) transporter
OXB_2216	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OXB_2217	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_2218	COG1116	anion transmembrane transporter activity
OXB_2219	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OXB_2220	COG0174	glutamine synthetase
OXB_2221	COG3377	Domain of unknown function (DUF1805)
OXB_2224	COG2076	Multidrug Resistance protein
OXB_2225	COG2076	Multidrug Resistance protein
OXB_2227	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_2230	COG1690	Belongs to the RtcB family
OXB_2232	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OXB_2234	COG0778	Nitroreductase
OXB_2238	COG2323	membrane
OXB_2242	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OXB_2244	COG0688	phosphatidylethanolamine metabolic process
OXB_2246	COG2030	dehydratase
OXB_2250	COG1595	DNA-templated transcription, initiation
OXB_2252	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_2253	COG3243	poly(R)-hydroxyalkanoic acid synthase
OXB_2255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OXB_2256	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OXB_2259	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_2261	COG2027	D-alanyl-D-alanine carboxypeptidase
OXB_2263	COG0564	pseudouridine synthase activity
OXB_2266	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OXB_2268	COG4120	Belongs to the binding-protein-dependent transport system permease family
OXB_2269	COG1116	anion transmembrane transporter activity
OXB_2269	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OXB_2270	COG5001	Diguanylate cyclase
OXB_2270	COG3300	MHYT domain
OXB_2271	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OXB_2272	COG0708	Exodeoxyribonuclease III
OXB_2273	COG2807	transmembrane transport
OXB_2274	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OXB_2275	COG2233	PERMEase
OXB_2276	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OXB_2277	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OXB_2278	COG1316	TRANSCRIPTIONal
OXB_2280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OXB_2282	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_2284	COG0667	Aldo Keto reductase
OXB_2285	COG0494	nUDIX hydrolase
OXB_2287	COG0735	belongs to the Fur family
OXB_2288	COG4974	Belongs to the 'phage' integrase family
OXB_2290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OXB_2292	COG0305	Participates in initiation and elongation during chromosome replication
OXB_2296	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OXB_2297	COG0732	type I restriction modification DNA specificity domain
OXB_2298	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OXB_2301	COG1191	sigma factor activity
OXB_2302	COG0697	spore germination
OXB_2303	COG0019	diaminopimelate decarboxylase activity
OXB_2305	COG1547	Domain of unknown function (DUF309)
OXB_2308	COG1686	Belongs to the peptidase S11 family
OXB_2309	COG1187	pseudouridine synthase activity
OXB_2310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_2311	COG1333	cytochrome c biogenesis protein
OXB_2312	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OXB_2313	COG0745	RESPONSE REGULATOR receiver
OXB_2314	COG5002	protein histidine kinase activity
OXB_2315	COG1595	DNA-templated transcription, initiation
OXB_2317	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OXB_2318	COG1141	Ferredoxin
OXB_2319	COG4955	Helix-turn-helix domain
OXB_2320	COG0514	ATP-dependent DNA helicase (RecQ)
OXB_2322	COG1408	metallophosphoesterase
OXB_2323	COG0492	ferredoxin-NADP+ reductase activity
OXB_2324	COG2339	peptidase activity
OXB_2325	COG3409	Peptidoglycan-binding domain 1 protein
OXB_2325	COG3773	Cell wall hydrolase
OXB_2330	COG0539	negative regulation of cytoplasmic translation
OXB_2335	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OXB_2339	COG0142	geranyltranstransferase activity
OXB_2342	COG0105	UTP biosynthetic process
OXB_2343	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OXB_2346	COG4401	Chorismate mutase type I
OXB_2348	COG0287	Prephenate dehydrogenase
OXB_2349	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OXB_2350	COG0457	Tetratricopeptide repeat
OXB_2351	COG5582	Belongs to the UPF0302 family
OXB_2353	COG0723	plastoquinol--plastocyanin reductase activity
OXB_2356	COG4347	Protein of unknown function (DUF1405)
OXB_2357	COG2738	Putative neutral zinc metallopeptidase
OXB_2358	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_2359	COG1694	Mazg nucleotide pyrophosphohydrolase
OXB_2361	COG0438	transferase activity, transferring glycosyl groups
OXB_2363	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OXB_2363	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OXB_2366	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OXB_2367	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OXB_2367	COG1199	ATP-dependent helicase activity
OXB_2370	COG3935	DnaD domain protein
OXB_2371	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OXB_2373	COG4499	WXG100 protein secretion system (Wss), protein YukC
OXB_2373	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OXB_2375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OXB_2378	COG0786	glutamate:sodium symporter activity
OXB_2379	COG1301	dicarboxylic acid transport
OXB_2380	COG0805	protein transport
OXB_2383	COG0765	amino acid transport
OXB_2388	COG1012	belongs to the aldehyde dehydrogenase family
OXB_2389	COG2204	response regulator
OXB_2390	COG3852	Histidine kinase
OXB_2393	COG0494	nUDIX hydrolase
OXB_2395	COG4638	Rieske (2fe-2S)
OXB_2396	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OXB_2397	COG4977	sequence-specific DNA binding
OXB_2397	COG1917	Cupin 2, conserved barrel domain protein
OXB_2398	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_2406	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_2410	COG3336	cytochrome c oxidase
OXB_2411	COG0778	Nitroreductase
OXB_2413	COG1132	(ABC) transporter
OXB_2418	COG0693	protein deglycase activity
OXB_2418	COG0753	catalase activity
OXB_2427	COG5001	Diguanylate cyclase
OXB_2427	COG3300	MHYT domain
OXB_2429	COG0535	radical SAM domain protein
OXB_2432	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OXB_2437	COG4842	Belongs to the WXG100 family
OXB_2438	COG5417	Belongs to the EsaB family
OXB_2439	COG4499	WXG100 protein secretion system (Wss), protein YukC
OXB_2440	COG1674	ftsk spoiiie
OXB_2440	COG0433	COG0433 Predicted ATPase
OXB_2441	COG1511	domain protein
OXB_2451	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OXB_2456	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OXB_2460	COG0765	amino acid transport
OXB_2461	COG1126	abc transporter atp-binding protein
OXB_2466	COG1834	amidinotransferase
OXB_2475	COG1205	dead DEAH box helicase
OXB_2475	COG1111	helicase
OXB_2481	COG3359	exonuclease
OXB_2482	COG3599	regulation of cell shape
OXB_2484	COG0116	Belongs to the methyltransferase superfamily
OXB_2485	COG1199	ATP-dependent helicase activity
OXB_2487	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OXB_2490	COG0328	RNA-DNA hybrid ribonuclease activity
OXB_2493	COG1827	regulation of RNA biosynthetic process
OXB_2494	COG1104	cysteine desulfurase activity
OXB_2495	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OXB_2496	COG0157	Belongs to the NadC ModD family
OXB_2497	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OXB_2498	COG2321	neutral zinc metallopeptidase
OXB_2502	COG4569	acetaldehyde dehydrogenase (acetylating) activity
OXB_2503	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OXB_2506	COG1942	4-Oxalocrotonate Tautomerase
OXB_2509	COG0840	transmembrane signaling receptor activity
OXB_2512	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_2515	COG1131	(ABC) transporter
OXB_2518	COG0488	(ABC) transporter
OXB_2519	COG1413	lyase activity
OXB_2521	COG2136	Putative SAM-dependent methyltransferase
OXB_2521	COG2521	methyltransferase
OXB_2523	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OXB_2524	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OXB_2525	COG1307	EDD domain protein, DegV family
OXB_2526	COG2755	lipolytic protein G-D-S-L family
OXB_2528	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OXB_2530	COG4479	Belongs to the UPF0346 family
OXB_2531	COG0813	purine-nucleoside phosphorylase activity
OXB_2532	COG0793	Belongs to the peptidase S41A family
OXB_2532	COG3409	Peptidoglycan-binding domain 1 protein
OXB_2534	COG2340	Cysteine-rich secretory protein family
OXB_2535	COG0697	spore germination
OXB_2539	COG0534	Mate efflux family protein
OXB_2540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OXB_2541	COG0567	Dehydrogenase, E1 component
OXB_2542	COG0508	dehydrogenase complex catalyzes the overall conversion of
OXB_2544	COG0714	Associated with various cellular activities
OXB_2545	COG4548	von Willebrand factor, type A
OXB_2546	COG3853	Toxic anion resistance protein (TelA)
OXB_2547	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OXB_2550	COG1278	Cold shock
OXB_2552	COG0488	(ABC) transporter
OXB_2554	COG1376	ErfK ybiS ycfS ynhG family protein
OXB_2557	COG1121	(ABC) transporter
OXB_2566	COG0840	transmembrane signaling receptor activity
OXB_2567	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OXB_2568	COG1316	TRANSCRIPTIONal
OXB_2569	COG0628	permease
OXB_2573	COG1846	Transcriptional regulator
OXB_2574	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_2576	COG0697	spore germination
OXB_2580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OXB_2581	COG3383	formate dehydrogenase (NAD+) activity
OXB_2582	COG2427	Protein of unknown function (DUF1641)
OXB_2586	COG5522	Integral membrane protein (intg_mem_TP0381)
OXB_2587	COG3858	chitin binding
OXB_2587	COG1388	LysM domain
OXB_2589	COG4260	virion core protein, lumpy skin disease virus
OXB_2591	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OXB_2591	COG0723	plastoquinol--plastocyanin reductase activity
OXB_2595	COG5002	protein histidine kinase activity
OXB_2596	COG0745	RESPONSE REGULATOR receiver
OXB_2597	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OXB_2598	COG0187	DNA topoisomerase II activity
OXB_2599	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OXB_2600	COG4841	protein insertion into membrane
OXB_2601	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_2602	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_2604	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OXB_2608	COG0410	ABC transporter
OXB_2609	COG0411	ABC transporter
OXB_2611	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OXB_2612	COG2030	dehydratase
OXB_2613	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_2616	COG2909	trisaccharide binding
OXB_2618	COG0824	Thioesterase
OXB_2619	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OXB_2620	COG1335	isochorismatase
OXB_2625	COG1999	signal sequence binding
OXB_2630	COG4846	Membrane protein involved in cytochrome C biogenesis
OXB_2631	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_2632	COG0785	Cytochrome C biogenesis protein
OXB_2634	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OXB_2636	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OXB_2637	COG0477	Major facilitator Superfamily
OXB_2640	COG3300	MHYT domain
OXB_2640	COG5001	Diguanylate cyclase
OXB_2643	COG1061	Type III restriction enzyme res subunit
OXB_2644	COG0494	nUDIX hydrolase
OXB_2645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OXB_2653	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OXB_2654	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OXB_2656	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OXB_2659	COG0305	Participates in initiation and elongation during chromosome replication
OXB_2665	COG1595	DNA-templated transcription, initiation
OXB_2666	COG0726	polysaccharide deacetylase
OXB_2667	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OXB_2667	COG2755	lipolytic protein G-D-S-L family
OXB_2669	COG3973	AAA domain
OXB_2671	COG0577	efflux transmembrane transporter activity
OXB_2672	COG1136	(ABC) transporter
OXB_2673	COG1819	glycosyl
OXB_2674	COG3620	sequence-specific DNA binding
OXB_2677	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OXB_2678	COG2258	MOSC domain
OXB_2681	COG0183	Belongs to the thiolase family
OXB_2682	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_2683	COG1268	BioY protein
OXB_2685	COG3485	protocatechuate 3,4-dioxygenase
OXB_2688	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OXB_2689	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OXB_2693	COG1414	Transcriptional regulator
OXB_2695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OXB_2697	COG5002	protein histidine kinase activity
OXB_2700	COG0745	RESPONSE REGULATOR receiver
OXB_2710	COG2207	Transcriptional regulator
OXB_2712	COG0659	secondary active sulfate transmembrane transporter activity
OXB_2714	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_2715	COG0300	oxidoreductase activity
OXB_2716	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_2717	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OXB_2718	COG1902	pentaerythritol trinitrate reductase activity
OXB_2720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OXB_2721	COG0835	chemotaxis
OXB_2722	COG2195	Cleaves the N-terminal amino acid of tripeptides
OXB_2723	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OXB_2724	COG0346	lactoylglutathione lyase activity
OXB_2726	COG1703	isobutyryl-CoA mutase activity
OXB_2727	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_2727	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_2728	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OXB_2729	COG0508	dehydrogenase complex catalyzes the overall conversion of
OXB_2730	COG0022	dehydrogenase e1 component
OXB_2731	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OXB_2732	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OXB_2734	COG3290	protein histidine kinase activity
OXB_2734	COG3829	transcription factor binding
OXB_2736	COG0584	glycerophosphoryl diester phosphodiesterase
OXB_2739	COG0750	zinc metalloprotease
OXB_2740	COG0497	DNA recombination
OXB_2742	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OXB_2743	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OXB_2744	COG0142	geranyltranstransferase activity
OXB_2749	COG1302	Protein conserved in bacteria
OXB_2750	COG0439	Biotin carboxylase
OXB_2751	COG0511	ligase activity, forming carbon-carbon bonds
OXB_2757	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OXB_2758	COG0006	proline dipeptidase activity
OXB_2760	COG3872	metal-dependent enzyme
OXB_2762	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OXB_2765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OXB_2769	COG2030	dehydratase
OXB_2770	COG4670	ketone body catabolic process
OXB_2771	COG0583	DNA-binding transcription factor activity
OXB_2772	COG1414	Transcriptional regulator
OXB_2773	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OXB_2774	COG0667	Aldo Keto reductase
OXB_2779	COG1012	belongs to the aldehyde dehydrogenase family
OXB_2783	COG0673	inositol 2-dehydrogenase activity
OXB_2785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_2787	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_2788	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_2791	COG1012	belongs to the aldehyde dehydrogenase family
OXB_2792	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OXB_2793	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OXB_2794	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OXB_2795	COG2186	Transcriptional regulator
OXB_2796	COG0710	3-dehydroquinate dehydratase activity
OXB_2799	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OXB_2800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OXB_2805	COG4537	Required for transformation and DNA binding
OXB_2807	COG1525	nuclease
OXB_2823	COG3628	GPW Gp25 family protein
OXB_2847	COG1783	phage Terminase large subunit
OXB_2848	COG3728	DNA packaging
OXB_2848	COG5484	DNA packaging
OXB_2857	COG3331	DNA recombination
OXB_2872	COG1484	DNA-dependent DNA replication
OXB_2873	COG1522	sequence-specific DNA binding
OXB_2891	COG0582	viral genome integration into host DNA
OXB_2893	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OXB_2895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_2898	COG1368	sulfuric ester hydrolase activity
OXB_2900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OXB_2901	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OXB_2906	COG2839	Protein conserved in bacteria
OXB_2910	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OXB_2911	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OXB_2912	COG0735	belongs to the Fur family
OXB_2913	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OXB_2914	COG1121	(ABC) transporter
OXB_2917	COG0513	Belongs to the DEAD box helicase family
OXB_2922	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OXB_2923	COG0733	neurotransmitter:sodium symporter activity
OXB_2924	COG1522	sequence-specific DNA binding
OXB_2926	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OXB_2927	COG2384	SAM-dependent methyltransferase
OXB_2929	COG1960	acyl-CoA dehydrogenase activity
OXB_2931	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OXB_2932	COG0358	DNA primase activity
OXB_2934	COG0517	IMP dehydrogenase activity
OXB_2935	COG0423	glycine-tRNA ligase activity
OXB_2936	COG1381	Involved in DNA repair and RecF pathway recombination
OXB_2939	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OXB_2941	COG1480	7TM receptor with intracellular HD hydrolase
OXB_2942	COG1702	phosphate starvation-inducible protein PhoH
OXB_2946	COG4864	UPF0365 protein
OXB_2947	COG1030	water channel activity
OXB_2952	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_2957	COG4974	Belongs to the 'phage' integrase family
OXB_2985	COG0740	serine-type endopeptidase activity
OXB_2990	COG0582	viral genome integration into host DNA
OXB_3008	COG0305	Participates in initiation and elongation during chromosome replication
OXB_3019	COG1396	sequence-specific DNA binding
OXB_3024	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OXB_3025	COG2264	protein methyltransferase activity
OXB_3028	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OXB_3030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OXB_3031	COG0481	GTPase activity
OXB_3033	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OXB_3034	COG0268	Binds directly to 16S ribosomal RNA
OXB_3035	COG1466	dna polymerase III delta subunit
OXB_3037	COG0658	competence protein
OXB_3037	COG2333	competence protein COMEC
OXB_3038	COG2131	deaminase
OXB_3040	COG2226	methyltransferase
OXB_3041	COG0799	negative regulation of ribosome biogenesis
OXB_3042	COG1713	HD superfamily hydrolase involved in NAD metabolism
OXB_3043	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OXB_3044	COG1534	Rna-binding protein
OXB_3046	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OXB_3047	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OXB_3048	COG1191	sigma factor activity
OXB_3051	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OXB_3052	COG0572	uridine kinase
OXB_3054	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OXB_3055	COG3906	Belongs to the UPF0473 family
OXB_3056	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OXB_3057	COG4472	Bacterial protein of unknown function (DUF965)
OXB_3058	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OXB_3059	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OXB_3060	COG0457	Tetratricopeptide repeat
OXB_3062	COG1104	cysteine desulfurase activity
OXB_3063	COG1959	2 iron, 2 sulfur cluster binding
OXB_3064	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OXB_3065	COG0835	chemotaxis
OXB_3065	COG0784	Response regulator, receiver
OXB_3067	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OXB_3068	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OXB_3070	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OXB_3071	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OXB_3074	COG0860	N-Acetylmuramoyl-L-alanine amidase
OXB_3074	COG3103	Sh3 type 3 domain protein
OXB_3074	COG4991	sh3 domain protein
OXB_3077	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OXB_3078	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OXB_3079	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OXB_3079	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OXB_3080	COG5416	Lipopolysaccharide assembly protein A domain
OXB_3081	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OXB_3081	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OXB_3083	COG2244	polysaccharide biosynthetic process
OXB_3084	COG2323	membrane
OXB_3085	COG1862	Preprotein translocase
OXB_3086	COG0343	queuine tRNA-ribosyltransferase activity
OXB_3090	COG0217	transcriptional regulatory protein
OXB_3093	COG0077	Prephenate dehydratase
OXB_3095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OXB_3099	COG2868	ribosomal protein
OXB_3102	COG0693	protein deglycase activity
OXB_3102	COG0753	catalase activity
OXB_3103	COG1994	Peptidase M50
OXB_3103	COG0517	IMP dehydrogenase activity
OXB_3105	COG2894	cell division
OXB_3106	COG0850	regulation of cytokinetic process
OXB_3108	COG1792	Involved in formation and maintenance of cell shape
OXB_3109	COG1077	Cell shape determining protein MreB Mrl
OXB_3110	COG2003	Belongs to the UPF0758 family
OXB_3111	COG0424	maF-like protein
OXB_3113	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OXB_3118	COG1459	type II secretion system
OXB_3120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OXB_3126	COG3706	GGDEF domain
OXB_3126	COG0745	RESPONSE REGULATOR receiver
OXB_3127	COG3706	GGDEF domain
OXB_3127	COG0745	RESPONSE REGULATOR receiver
OXB_3128	COG0285	dihydrofolate synthase activity
OXB_3129	COG0189	ligase activity
OXB_3132	COG0154	amidase activity
OXB_3133	COG0525	valine-tRNA ligase activity
OXB_3137	COG0113	porphobilinogen synthase activity
OXB_3140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OXB_3142	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OXB_3143	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OXB_3145	COG0544	peptidyl-prolyl cis-trans isomerase activity
OXB_3148	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_3148	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_3150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OXB_3151	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OXB_3152	COG1024	Enoyl-CoA hydratase
OXB_3153	COG1053	succinate dehydrogenase
OXB_3154	COG4670	ketone body catabolic process
OXB_3155	COG1960	acyl-CoA dehydrogenase activity
OXB_3156	COG1012	belongs to the aldehyde dehydrogenase family
OXB_3159	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OXB_3160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OXB_3163	COG1929	Belongs to the glycerate kinase type-1 family
OXB_3164	COG1802	Transcriptional regulator
OXB_3167	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_3169	COG2197	response regulator
OXB_3173	COG1012	belongs to the aldehyde dehydrogenase family
OXB_3178	COG0789	Transcriptional regulator
OXB_3178	COG4978	Transcriptional regulator
OXB_3181	COG2030	dehydratase
OXB_3186	COG3290	protein histidine kinase activity
OXB_3186	COG0840	transmembrane signaling receptor activity
OXB_3191	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OXB_3192	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OXB_3195	COG2197	response regulator
OXB_3196	COG0824	Thioesterase
OXB_3197	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OXB_3198	COG1053	succinate dehydrogenase
OXB_3199	COG2009	succinate dehydrogenase
OXB_3200	COG1719	4-vinyl reductase, 4VR
OXB_3201	COG0322	excinuclease ABC activity
OXB_3202	COG3118	belongs to the thioredoxin family
OXB_3203	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OXB_3204	COG2086	electron transfer activity
OXB_3205	COG1024	Enoyl-CoA hydratase
OXB_3206	COG1309	transcriptional regulator
OXB_3207	COG0318	PFAM AMP-dependent synthetase and ligase
OXB_3208	COG3766	membrane
OXB_3209	COG1193	negative regulation of DNA recombination
OXB_3210	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OXB_3210	COG1796	DNA polymerase
OXB_3216	COG0072	phenylalanine-tRNA ligase activity
OXB_3216	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OXB_3218	COG1335	isochorismatase
OXB_3221	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OXB_3223	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OXB_3224	COG1363	Peptidase, m42
OXB_3228	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OXB_3229	COG0514	ATP-dependent DNA helicase (RecQ)
OXB_3233	COG2188	Transcriptional regulator
OXB_3234	COG0726	polysaccharide deacetylase
OXB_3236	COG0492	ferredoxin-NADP+ reductase activity
OXB_3241	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OXB_3244	COG0604	alcohol dehydrogenase
OXB_3251	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OXB_3252	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OXB_3253	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OXB_3254	COG1484	DNA-dependent DNA replication
OXB_3255	COG3611	Membrane attachment protein
OXB_3257	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OXB_3258	COG0237	dephospho-CoA kinase activity
OXB_3259	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OXB_3260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OXB_3260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OXB_3261	COG0330	HflC and HflK could
OXB_3262	COG0330	HflC and HflK could
OXB_3263	COG5002	protein histidine kinase activity
OXB_3264	COG0745	RESPONSE REGULATOR receiver
OXB_3266	COG0039	L-malate dehydrogenase activity
OXB_3267	COG0538	isocitrate dehydrogenase activity
OXB_3268	COG0372	Belongs to the citrate synthase family
OXB_3269	COG0628	permease
OXB_3270	COG3030	protein affecting phage T7 exclusion by the F plasmid
OXB_3272	COG0205	6-phosphofructokinase activity
OXB_3273	COG0825	malonyl-CoA metabolic process
OXB_3275	COG1725	Transcriptional regulator
OXB_3276	COG0587	DNA-directed DNA polymerase activity
OXB_3277	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OXB_3279	COG4109	DRTGG domain
OXB_3281	COG0006	proline dipeptidase activity
OXB_3284	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OXB_3285	COG0827	DNA restriction-modification system
OXB_3286	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OXB_3287	COG1714	RDD family
OXB_3288	COG0616	signal peptide processing
OXB_3289	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OXB_3291	COG2962	Rard protein
OXB_3292	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OXB_3295	COG1104	cysteine desulfurase activity
OXB_3296	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OXB_3297	COG1956	GAF domain-containing protein
OXB_3298	COG0626	cystathionine gamma-synthase activity
OXB_3299	COG2203	Gaf domain
OXB_3299	COG2199	diguanylate cyclase activity
OXB_3302	COG1793	dna ligase
OXB_3302	COG3285	dna ligase
OXB_3304	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OXB_3306	COG0477	Major facilitator Superfamily
OXB_3307	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OXB_3308	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OXB_3309	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OXB_3310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OXB_3311	COG0454	-acetyltransferase
OXB_3312	COG0517	IMP dehydrogenase activity
OXB_3313	COG0123	including yeast histone deacetylase and acetoin utilization protein
OXB_3315	COG1605	Chorismate mutase
OXB_3315	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OXB_3316	COG0849	cell division
OXB_3317	COG4980	gas vesicle protein
OXB_3320	COG1674	ftsk spoiiie
OXB_3321	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OXB_3322	COG4848	Belongs to the UPF0354 family
OXB_3324	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OXB_3325	COG1363	Peptidase, m42
OXB_3328	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OXB_3332	COG1349	DNA-binding transcription factor activity
OXB_3333	COG1187	pseudouridine synthase activity
OXB_3334	COG2244	polysaccharide biosynthetic process
OXB_3335	COG1012	belongs to the aldehyde dehydrogenase family
OXB_3337	COG2081	HI0933 family
OXB_3339	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OXB_3340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OXB_3341	COG1242	4 iron, 4 sulfur cluster binding
OXB_3342	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OXB_3343	COG1119	ATPase activity
OXB_3344	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_3354	COG0628	permease
OXB_3355	COG0534	Mate efflux family protein
OXB_3357	COG3739	integral membrane protein
OXB_3358	COG3655	Transcriptional regulator
OXB_3363	COG3583	domain protein
OXB_3363	COG3584	3D domain protein
OXB_3364	COG1802	Transcriptional regulator
OXB_3365	COG1114	Component of the transport system for branched-chain amino acids
OXB_3367	COG0420	3'-5' exonuclease activity
OXB_3368	COG0803	Belongs to the bacterial solute-binding protein 9 family
OXB_3369	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OXB_3370	COG1121	(ABC) transporter
OXB_3374	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OXB_3375	COG2135	peptidase activity
OXB_3378	COG2814	Major facilitator Superfamily
OXB_3379	COG1846	Transcriptional regulator
OXB_3380	COG2223	nitrite transmembrane transporter activity
OXB_3381	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OXB_3387	COG1164	Oligoendopeptidase f
OXB_3388	COG1464	Belongs to the NlpA lipoprotein family
OXB_3389	COG1464	Belongs to the NlpA lipoprotein family
OXB_3390	COG2011	ABC-type metal ion transport system permease component
OXB_3391	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OXB_3392	COG0436	Aminotransferase
OXB_3395	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OXB_3396	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OXB_3396	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OXB_3397	COG0307	riboflavin synthase, alpha
OXB_3398	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_3398	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OXB_3400	COG2113	Glycine betaine
OXB_3401	COG4176	ABC-type proline glycine betaine transport system permease component
OXB_3402	COG0517	IMP dehydrogenase activity
OXB_3402	COG4175	Glycine betaine
OXB_3403	COG1510	regulation of RNA biosynthetic process
OXB_3404	COG0840	transmembrane signaling receptor activity
OXB_3404	COG3290	protein histidine kinase activity
OXB_3406	COG0745	RESPONSE REGULATOR receiver
OXB_3407	COG5002	protein histidine kinase activity
OXB_3408	COG1999	signal sequence binding
OXB_3411	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OXB_3414	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OXB_3415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OXB_3415	COG0140	phosphoribosyl-ATP diphosphatase activity
OXB_3416	COG0107	imidazoleglycerol-phosphate synthase activity
OXB_3417	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OXB_3418	COG0131	Imidazoleglycerol-phosphate dehydratase
OXB_3419	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OXB_3420	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OXB_3421	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OXB_3422	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OXB_3424	COG1595	DNA-templated transcription, initiation
OXB_3425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OXB_3427	COG0697	spore germination
OXB_3433	COG1131	(ABC) transporter
OXB_3436	COG1012	belongs to the aldehyde dehydrogenase family
OXB_3437	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OXB_3449	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OXB_3451	COG0789	Transcriptional regulator
OXB_3451	COG4978	Transcriptional regulator
OXB_3453	COG0583	DNA-binding transcription factor activity
OXB_3456	COG0137	argininosuccinate synthase activity
OXB_3457	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OXB_3459	COG1388	LysM domain
OXB_3459	COG3858	chitin binding
OXB_3460	COG5577	PFAM Coat F domain
OXB_3462	COG0564	pseudouridine synthase activity
OXB_3465	COG0281	malic enzyme
OXB_3466	COG2323	membrane
OXB_3468	COG1960	acyl-CoA dehydrogenase activity
OXB_3470	COG2002	toxin-antitoxin pair type II binding
OXB_3473	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OXB_3474	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OXB_3477	COG0739	heme binding
OXB_3478	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OXB_3480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OXB_3482	COG0598	Magnesium transport protein CorA
OXB_3485	COG0840	transmembrane signaling receptor activity
OXB_3488	COG0471	metal ion transport
OXB_3488	COG0490	domain, Protein
OXB_3489	COG0753	catalase activity
OXB_3492	COG0745	RESPONSE REGULATOR receiver
OXB_3494	COG0840	transmembrane signaling receptor activity
OXB_3496	COG0697	spore germination
OXB_3498	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OXB_3499	COG1012	belongs to the aldehyde dehydrogenase family
OXB_3500	COG1404	Belongs to the peptidase S8 family
OXB_3501	COG1132	(ABC) transporter
OXB_3508	COG0745	RESPONSE REGULATOR receiver
OXB_3509	COG5002	protein histidine kinase activity
OXB_3510	COG0133	tryptophan synthase activity
OXB_3511	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OXB_3514	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
OXB_3517	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OXB_3518	COG0726	polysaccharide deacetylase
OXB_3521	COG1982	Orn Lys Arg decarboxylase major
OXB_3522	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OXB_3523	COG0010	Belongs to the arginase family
OXB_3526	COG3706	GGDEF domain
OXB_3526	COG4251	negative regulation of phosphorylation
OXB_3526	COG2203	Gaf domain
OXB_3526	COG5001	Diguanylate cyclase
OXB_3527	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_3528	COG0765	amino acid transport
OXB_3529	COG1126	abc transporter atp-binding protein
OXB_3532	COG2124	cytochrome p450
OXB_3534	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OXB_3535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OXB_3536	COG1268	BioY protein
OXB_3537	COG1752	Esterase of the alpha-beta hydrolase superfamily
OXB_3538	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OXB_3539	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OXB_3542	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OXB_3543	COG0765	amino acid transport
OXB_3544	COG1126	abc transporter atp-binding protein
OXB_3545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OXB_3545	COG1648	precorrin-2 dehydrogenase activity
OXB_3548	COG0529	Catalyzes the synthesis of activated sulfate
OXB_3550	COG0175	sulfate reduction
OXB_3555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OXB_3556	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OXB_3557	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OXB_3558	COG1028	Short-chain dehydrogenase reductase Sdr
OXB_3564	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OXB_3567	COG1695	Transcriptional regulator
OXB_3571	COG1671	Belongs to the UPF0178 family
OXB_3573	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OXB_3574	COG3424	synthase
OXB_3575	COG1755	Isoprenylcysteine carboxyl methyltransferase
OXB_3577	COG1525	nuclease
OXB_3578	COG1785	Belongs to the alkaline phosphatase family
OXB_3579	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OXB_3580	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OXB_3581	COG0210	DNA helicase
OXB_3584	COG0681	Belongs to the peptidase S26 family
OXB_3585	COG0840	transmembrane signaling receptor activity
OXB_3586	COG2267	carboxylic ester hydrolase activity
OXB_3587	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily