locus-tag	class	description
H7F24_00010	COG1575	Belongs to the MenA family. Type 1 subfamily
H7F24_00015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F24_00145	COG3859	Proton-coupled thiamine transporter YuaJ
H7F24_00155	COG1247	-acetyltransferase
H7F24_00160	COG3339	Conserved Protein
H7F24_00165	COG0772	Belongs to the SEDS family
H7F24_00170	COG0772	Belongs to the SEDS family
H7F24_00175	COG2268	Band 7 protein
H7F24_00180	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7F24_00185	COG2318	DinB family
H7F24_00190	COG1454	alcohol dehydrogenase
H7F24_00195	COG1012	belongs to the aldehyde dehydrogenase family
H7F24_00200	COG1510	regulation of RNA biosynthetic process
H7F24_00225	COG3409	Peptidoglycan-binding domain 1 protein
H7F24_00225	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F24_00280	COG3778	Protein conserved in bacteria
H7F24_00285	COG3299	homolog of phage Mu protein gp47
H7F24_00290	COG3628	GPW Gp25 family protein
H7F24_00300	COG4193	domain, Protein
H7F24_00305	COG1652	LysM domain
H7F24_00310	COG3953	SLT domain
H7F24_00310	COG5280	Phage tail tape measure protein TP901
H7F24_00310	COG3953	SLT domain
H7F24_00310	COG5280	Phage tail tape measure protein TP901
H7F24_00365	COG4653	Phage capsid family
H7F24_00370	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H7F24_00375	COG5518	Phage portal protein
H7F24_00380	COG1783	phage Terminase large subunit
H7F24_00385	COG5484	DNA packaging
H7F24_00390	COG1595	DNA-templated transcription, initiation
H7F24_00400	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
H7F24_00420	COG1396	sequence-specific DNA binding
H7F24_00430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7F24_00440	COG1968	undecaprenyl-diphosphatase activity
H7F24_00445	COG0628	permease
H7F24_00455	COG0673	inositol 2-dehydrogenase activity
H7F24_00460	COG0693	protein deglycase activity
H7F24_00465	COG0840	transmembrane signaling receptor activity
H7F24_00470	COG0840	transmembrane signaling receptor activity
H7F24_00475	COG0840	transmembrane signaling receptor activity
H7F24_00480	COG0840	transmembrane signaling receptor activity
H7F24_00495	COG2070	2-Nitropropane dioxygenase
H7F24_00500	COG0432	Pfam Uncharacterised protein family UPF0047
H7F24_00505	COG1253	flavin adenine dinucleotide binding
H7F24_00510	COG2738	Putative neutral zinc metallopeptidase
H7F24_00520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7F24_00535	COG0166	Belongs to the GPI family
H7F24_00540	COG1979	alcohol dehydrogenase
H7F24_00545	COG1979	alcohol dehydrogenase
H7F24_00550	COG2155	Conserved Protein
H7F24_00555	COG1098	S1 RNA binding domain
H7F24_00560	COG0436	Aminotransferase
H7F24_00565	COG1522	sequence-specific DNA binding
H7F24_00570	COG2267	carboxylic ester hydrolase activity
H7F24_00580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7F24_00585	COG2205	protein histidine kinase activity
H7F24_00600	COG5018	Exonuclease
H7F24_00605	COG2814	Major facilitator Superfamily
H7F24_00610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F24_00615	COG3011	Protein conserved in bacteria
H7F24_00625	COG3290	protein histidine kinase activity
H7F24_00630	COG4565	transcriptional regulatory protein
H7F24_00635	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F24_00640	COG3845	ABC transporter
H7F24_00645	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7F24_00650	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F24_00655	COG3493	citrate carrier protein
H7F24_00665	COG2111	Na H antiporter
H7F24_00665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F24_00670	COG2111	Na H antiporter
H7F24_00675	COG1006	Multisubunit Na H antiporter MnhC subunit
H7F24_00680	COG0651	ATP synthesis coupled electron transport
H7F24_00685	COG1863	multisubunit Na H antiporter MnhE subunit
H7F24_00690	COG2212	antiporter activity
H7F24_00695	COG1320	monovalent cation:proton antiporter activity
H7F24_00700	COG2050	protein possibly involved in aromatic compounds catabolism
H7F24_00705	COG2197	response regulator
H7F24_00710	COG4585	Histidine kinase
H7F24_00720	COG0142	geranyltranstransferase activity
H7F24_00735	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7F24_00740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7F24_00745	COG1335	isochorismatase
H7F24_00750	COG5506	Protein of unknown function (DUF1694)
H7F24_00770	COG0628	permease
H7F24_00785	COG1418	mRNA catabolic process
H7F24_00790	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_00800	COG1511	domain protein
H7F24_00805	COG1674	ftsk spoiiie
H7F24_00805	COG0433	COG0433 Predicted ATPase
H7F24_00810	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F24_00815	COG5417	Belongs to the EsaB family
H7F24_00820	COG4842	Belongs to the WXG100 family
H7F24_00825	COG2508	Transcriptional regulator
H7F24_00825	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F24_00830	COG0686	Belongs to the AlaDH PNT family
H7F24_00835	COG1268	BioY protein
H7F24_00840	COG4326	sporulation control protein
H7F24_00845	COG2056	Na+-H+ antiporter family
H7F24_00850	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7F24_00855	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H7F24_00860	COG3584	3D domain protein
H7F24_00875	COG1252	NADH dehydrogenase
H7F24_00880	COG0492	ferredoxin-NADP+ reductase activity
H7F24_00890	COG0789	Transcriptional regulator
H7F24_00895	COG0316	Belongs to the HesB IscA family
H7F24_00900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7F24_00905	COG4844	belongs to the
H7F24_00910	COG1252	NADH dehydrogenase
H7F24_00920	COG4837	Protein of unknown function (DUF1462)
H7F24_00925	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H7F24_00930	COG0823	Involved in the tonB-independent uptake of proteins
H7F24_00930	COG1506	peptidase
H7F24_00930	COG4946	Tricorn protease homolog
H7F24_00935	COG0083	homoserine kinase activity
H7F24_00940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F24_00945	COG0460	homoserine dehydrogenase
H7F24_00950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F24_00955	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F24_00960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F24_00965	COG0647	UMP catabolic process
H7F24_00970	COG2445	Protein of unknown function DUF86
H7F24_00975	COG4470	Protein conserved in bacteria
H7F24_00985	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7F24_00990	COG0739	heme binding
H7F24_01000	COG3377	Domain of unknown function (DUF1805)
H7F24_01005	COG0737	Belongs to the 5'-nucleotidase family
H7F24_01010	COG1801	Protein of unknown function DUF72
H7F24_01015	COG2508	Transcriptional regulator
H7F24_01020	COG2140	Oxalate decarboxylase
H7F24_01025	COG2814	Major facilitator Superfamily
H7F24_01030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7F24_01035	COG2356	endonuclease I
H7F24_01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F24_01065	COG0561	phosphatase activity
H7F24_01075	COG5002	protein histidine kinase activity
H7F24_01075	COG0642	Histidine kinase
H7F24_01080	COG0745	RESPONSE REGULATOR receiver
H7F24_01085	COG2311	Membrane
H7F24_01095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F24_01105	COG1309	transcriptional regulator
H7F24_01110	COG0719	Fe-S assembly protein
H7F24_01115	COG0822	iron-sulfur transferase activity
H7F24_01120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F24_01125	COG0719	Fe-S assembly protein
H7F24_01130	COG0396	ATPase activity
H7F24_01135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F24_01140	COG1464	Belongs to the NlpA lipoprotein family
H7F24_01145	COG2011	ABC-type metal ion transport system permease component
H7F24_01150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F24_01160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_01165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F24_01175	COG0509	glycine decarboxylation via glycine cleavage system
H7F24_01180	COG1393	Belongs to the ArsC family
H7F24_01185	COG1960	acyl-CoA dehydrogenase activity
H7F24_01190	COG0183	Belongs to the thiolase family
H7F24_01195	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F24_01195	COG1024	Enoyl-CoA hydratase
H7F24_01210	COG5577	PFAM Coat F domain
H7F24_01220	COG1120	ATPase activity
H7F24_01230	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_01235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F24_01240	COG0745	RESPONSE REGULATOR receiver
H7F24_01245	COG2770	Histidine kinase
H7F24_01245	COG2205	protein histidine kinase activity
H7F24_01255	COG1309	transcriptional regulator
H7F24_01265	COG0114	fumarate hydratase activity
H7F24_01275	COG0697	spore germination
H7F24_01280	COG0814	amino acid
H7F24_01295	COG2197	response regulator
H7F24_01300	COG4585	Histidine kinase
H7F24_01305	COG4758	membrane
H7F24_01315	COG1842	Phage shock protein A
H7F24_01320	COG4758	membrane
H7F24_01325	COG2096	Adenosyltransferase
H7F24_01330	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_01335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7F24_01345	COG2204	response regulator
H7F24_01360	COG1454	alcohol dehydrogenase
H7F24_01365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F24_01375	COG1120	ATPase activity
H7F24_01380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_01385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F24_01395	COG2721	sulfolactate sulfo-lyase activity
H7F24_01400	COG0246	Mannitol dehydrogenase
H7F24_01405	COG1609	Transcriptional regulator
H7F24_01410	COG1904	glucuronate isomerase
H7F24_01415	COG2205	protein histidine kinase activity
H7F24_01420	COG0745	RESPONSE REGULATOR receiver
H7F24_01425	COG1120	ATPase activity
H7F24_01430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_01435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_01440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F24_01445	COG0531	amino acid
H7F24_01460	COG1988	membrane-bound metal-dependent
H7F24_01465	COG1368	sulfuric ester hydrolase activity
H7F24_01470	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7F24_01475	COG4149	molybdate abc transporter
H7F24_01480	COG0656	L-ascorbic acid biosynthetic process
H7F24_01485	COG1940	carbohydrate kinase activity
H7F24_01490	COG0025	NhaP-type Na H and K H
H7F24_01495	COG2860	membrane
H7F24_01500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7F24_01505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F24_01510	COG2217	Heavy metal translocating P-type atpase
H7F24_01515	COG1121	(ABC) transporter
H7F24_01520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F24_01525	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F24_01535	COG3226	Transcriptional regulator
H7F24_01540	COG0784	Response regulator, receiver
H7F24_01545	COG4191	Histidine kinase
H7F24_01550	COG1027	Aspartate ammonia-lyase
H7F24_01560	COG2217	Heavy metal translocating P-type atpase
H7F24_01565	COG2608	mercury ion transmembrane transporter activity
H7F24_01570	COG1937	Protein conserved in bacteria
H7F24_01620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7F24_01625	COG0557	exoribonuclease II activity
H7F24_01630	COG1647	Serine aminopeptidase, S33
H7F24_01635	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F24_01640	COG2002	toxin-antitoxin pair type II binding
H7F24_01645	COG1476	TRANSCRIPTIONal
H7F24_01650	COG1396	sequence-specific DNA binding
H7F24_01655	COG1396	sequence-specific DNA binding
H7F24_01660	COG1733	regulation of RNA biosynthetic process
H7F24_01665	COG1174	glycine betaine transport
H7F24_01670	COG1732	Glycine betaine
H7F24_01675	COG1174	glycine betaine transport
H7F24_01680	COG1125	glycine betaine transport
H7F24_01680	COG0517	IMP dehydrogenase activity
H7F24_01685	COG1510	regulation of RNA biosynthetic process
H7F24_01690	COG2095	MarC family integral membrane protein
H7F24_01700	COG0456	acetyltransferase
H7F24_01720	COG1122	ATPase activity
H7F24_01730	COG0148	phosphopyruvate hydratase activity
H7F24_01735	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7F24_01740	COG0149	triose-phosphate isomerase activity
H7F24_01745	COG0126	phosphoglycerate kinase activity
H7F24_01750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F24_01755	COG2390	Transcriptional regulator
H7F24_01760	COG0833	amino acid
H7F24_01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F24_01770	COG3829	transcription factor binding
H7F24_01775	COG2186	Transcriptional regulator
H7F24_01780	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F24_01790	COG0534	Mate efflux family protein
H7F24_01800	COG0444	Belongs to the ABC transporter superfamily
H7F24_01805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F24_01810	COG0601	transmembrane transport
H7F24_01815	COG0747	negative chemotaxis
H7F24_01820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F24_01825	COG0110	maltose O-acetyltransferase activity
H7F24_01830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7F24_01835	COG2244	polysaccharide biosynthetic process
H7F24_01840	COG5039	Polysaccharide pyruvyl transferase
H7F24_01845	COG1216	Glycosyl transferase, family 2
H7F24_01855	COG0438	transferase activity, transferring glycosyl groups
H7F24_01860	COG1215	transferase activity, transferring glycosyl groups
H7F24_01865	COG0438	transferase activity, transferring glycosyl groups
H7F24_01870	COG1086	Polysaccharide biosynthesis protein
H7F24_01875	COG0489	protein tyrosine kinase activity
H7F24_01880	COG3944	biosynthesis protein
H7F24_01885	COG1396	sequence-specific DNA binding
H7F24_01895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F24_01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_01905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_01910	COG0726	polysaccharide deacetylase
H7F24_01915	COG0488	(ABC) transporter
H7F24_01935	COG0601	transmembrane transport
H7F24_01940	COG0747	negative chemotaxis
H7F24_01945	COG1819	glycosyl
H7F24_01960	COG0740	serine-type endopeptidase activity
H7F24_01965	COG1611	Belongs to the LOG family
H7F24_01970	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F24_01975	COG0659	secondary active sulfate transmembrane transporter activity
H7F24_01980	COG0288	reversible hydration of carbon dioxide
H7F24_01985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F24_01995	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H7F24_02000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_02005	COG1481	regulation of sporulation
H7F24_02010	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H7F24_02015	COG1660	Displays ATPase and GTPase activities
H7F24_02020	COG1051	belongs to the nudix hydrolase family
H7F24_02025	COG0492	ferredoxin-NADP+ reductase activity
H7F24_02030	COG3883	PFAM NLP P60 protein
H7F24_02030	COG0791	NLP P60 protein
H7F24_02035	COG0457	Tetratricopeptide repeat
H7F24_02040	COG0140	phosphoribosyl-ATP diphosphatase activity
H7F24_02040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7F24_02045	COG0107	imidazoleglycerol-phosphate synthase activity
H7F24_02050	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7F24_02055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7F24_02060	COG0131	Imidazoleglycerol-phosphate dehydratase
H7F24_02065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7F24_02070	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7F24_02075	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H7F24_02080	COG4990	cell redox homeostasis
H7F24_02090	COG2910	NAD(P)H-binding
H7F24_02095	COG1959	2 iron, 2 sulfur cluster binding
H7F24_02100	COG0110	maltose O-acetyltransferase activity
H7F24_02105	COG0546	phosphoglycolate phosphatase activity
H7F24_02110	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H7F24_02120	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7F24_02125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7F24_02130	COG0363	glucosamine-6-phosphate deaminase activity
H7F24_02135	COG2188	Transcriptional regulator
H7F24_02140	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F24_02145	COG1950	PFAM Membrane protein of
H7F24_02150	COG1983	PspC domain protein
H7F24_02155	COG3595	metallopeptidase activity
H7F24_02170	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7F24_02180	COG4897	Protein conserved in bacteria
H7F24_02185	COG0574	Belongs to the PEP-utilizing enzyme family
H7F24_02185	COG3848	Pyruvate phosphate dikinase
H7F24_02190	COG1309	transcriptional regulator
H7F24_02195	COG2814	Major facilitator Superfamily
H7F24_02205	COG0745	RESPONSE REGULATOR receiver
H7F24_02210	COG5002	protein histidine kinase activity
H7F24_02215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F24_02220	COG0463	Glycosyl transferase, family 2
H7F24_02225	COG1113	amino acid transport
H7F24_02230	COG0778	Nitroreductase
H7F24_02235	COG1733	regulation of RNA biosynthetic process
H7F24_02240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F24_02250	COG3409	Peptidoglycan-binding domain 1 protein
H7F24_02250	COG0793	Belongs to the peptidase S41A family
H7F24_02255	COG0730	response to heat
H7F24_02260	COG3883	PFAM NLP P60 protein
H7F24_02260	COG0791	NLP P60 protein
H7F24_02265	COG2177	Part of the ABC transporter FtsEX involved in
H7F24_02270	COG2884	Cell division ATP-binding protein ftsE
H7F24_02275	COG2010	Cytochrome c
H7F24_02280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F24_02300	COG0653	protein targeting
H7F24_02305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7F24_02310	COG0840	transmembrane signaling receptor activity
H7F24_02325	COG1516	flagellar protein fliS
H7F24_02330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H7F24_02335	COG1334	flagellar protein FlaG
H7F24_02340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H7F24_02345	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
H7F24_02355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F24_02360	COG4786	Flagellar basal body rod
H7F24_02360	COG1256	bacterial-type flagellum assembly
H7F24_02365	COG3418	PFAM FlgN family protein
H7F24_02380	COG1040	competence protein
H7F24_02390	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H7F24_02395	COG1307	EDD domain protein, DegV family
H7F24_02400	COG2197	response regulator
H7F24_02405	COG4585	Histidine kinase
H7F24_02410	COG1739	Uncharacterized protein family UPF0029
H7F24_02415	COG1316	TRANSCRIPTIONal
H7F24_02420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F24_02425	COG0438	transferase activity, transferring glycosyl groups
H7F24_02430	COG1215	transferase activity, transferring glycosyl groups
H7F24_02435	COG3206	protein involved in exopolysaccharide biosynthesis
H7F24_02440	COG3307	-O-antigen
H7F24_02445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F24_02450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F24_02455	COG0438	transferase activity, transferring glycosyl groups
H7F24_02455	COG0297	glycogen (starch) synthase activity
H7F24_02460	COG2244	polysaccharide biosynthetic process
H7F24_02475	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F24_02475	COG2247	cell wall binding repeat
H7F24_02480	COG2247	cell wall binding repeat
H7F24_02480	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F24_02485	COG2247	cell wall binding repeat
H7F24_02485	COG2385	sporulation resulting in formation of a cellular spore
H7F24_02495	COG1316	TRANSCRIPTIONal
H7F24_02500	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7F24_02505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F24_02510	COG1134	teichoic acid transport
H7F24_02515	COG1682	transport, permease protein
H7F24_02525	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F24_02535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7F24_02540	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H7F24_02545	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F24_02550	COG4193	domain, Protein
H7F24_02555	COG1482	cell wall glycoprotein biosynthetic process
H7F24_02565	COG1175	transmembrane transport
H7F24_02570	COG1653	transport
H7F24_02575	COG2201	protein-glutamate methylesterase activity
H7F24_02580	COG2972	Histidine kinase
H7F24_02590	COG0454	-acetyltransferase
H7F24_02595	COG0800	Aldolase
H7F24_02600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F24_02605	COG1609	Transcriptional regulator
H7F24_02610	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H7F24_02615	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_02620	COG0697	spore germination
H7F24_02625	COG0814	amino acid
H7F24_02640	COG2814	Major facilitator Superfamily
H7F24_02645	COG1316	TRANSCRIPTIONal
H7F24_02650	COG0561	phosphatase activity
H7F24_02655	COG0791	NLP P60 protein
H7F24_02665	COG2843	Capsule synthesis protein
H7F24_02675	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F24_02680	COG0697	spore germination
H7F24_02695	COG1609	Transcriptional regulator
H7F24_02700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F24_02705	COG1869	D-ribose catabolic process
H7F24_02710	COG1129	ABC transporter
H7F24_02715	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F24_02720	COG1879	ABC-type sugar transport system periplasmic component
H7F24_02725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F24_02730	COG0583	DNA-binding transcription factor activity
H7F24_02735	COG0028	Belongs to the TPP enzyme family
H7F24_02740	COG3527	Alpha-acetolactate decarboxylase
H7F24_02745	COG1522	sequence-specific DNA binding
H7F24_02750	COG2059	Chromate
H7F24_02755	COG2059	Chromate
H7F24_02760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F24_02770	COG4715	Zinc finger, swim domain protein
H7F24_02775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F24_02780	COG2202	Pas domain
H7F24_02780	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_02785	COG0561	phosphatase activity
H7F24_02800	COG1970	mechanosensitive ion channel activity
H7F24_02805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F24_02810	COG0457	Tetratricopeptide repeat
H7F24_02815	COG4786	Flagellar basal body rod
H7F24_02820	COG4786	Flagellar basal body rod
H7F24_02825	COG1077	Cell shape determining protein MreB Mrl
H7F24_02830	COG1609	Transcriptional regulator
H7F24_02835	COG1846	Transcriptional regulator
H7F24_02840	COG2814	Major facilitator Superfamily
H7F24_02845	COG0671	phosphoesterase, PA-phosphatase related
H7F24_02850	COG0477	Major facilitator Superfamily
H7F24_02855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F24_02860	COG0765	amino acid transport
H7F24_02870	COG0004	ammonium transporteR
H7F24_02875	COG0347	Belongs to the P(II) protein family
H7F24_02880	COG0739	heme binding
H7F24_02885	COG1247	-acetyltransferase
H7F24_02925	COG0523	cobalamin synthesis protein
H7F24_02930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F24_02935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7F24_02940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7F24_02945	COG2223	nitrite transmembrane transporter activity
H7F24_02950	COG0243	molybdopterin cofactor binding
H7F24_02955	COG2304	oxidoreductase activity
H7F24_02960	COG2304	oxidoreductase activity
H7F24_02965	COG2385	sporulation resulting in formation of a cellular spore
H7F24_02970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F24_02980	COG4836	Membrane
H7F24_02990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7F24_02995	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7F24_03000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7F24_03005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H7F24_03010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F24_03015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7F24_03020	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F24_03025	COG0356	it plays a direct role in the translocation of protons across the membrane
H7F24_03035	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7F24_03040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7F24_03045	COG4475	Protein of unknown function (DUF436)
H7F24_03050	COG0698	ribose 5-phosphate isomerase
H7F24_03055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F24_03060	COG1971	Probably functions as a manganese efflux pump
H7F24_03065	COG0009	L-threonylcarbamoyladenylate synthase
H7F24_03070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7F24_03085	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F24_03090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7F24_03095	COG0789	Transcriptional regulator
H7F24_03100	COG0679	Auxin Efflux Carrier
H7F24_03105	COG0281	malic enzyme
H7F24_03110	COG1435	thymidine kinase activity
H7F24_03115	COG0254	rRNA binding
H7F24_03120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7F24_03125	COG1494	fructose-1,6-bisphosphatase
H7F24_03130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F24_03135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F24_03140	COG0191	fructose-bisphosphate aldolase activity
H7F24_03145	COG2204	response regulator
H7F24_03150	COG4821	SIS domain
H7F24_03155	COG0504	CTP synthase activity
H7F24_03160	COG3343	RNA polymerase activity
H7F24_03170	COG1960	acyl-CoA dehydrogenase activity
H7F24_03175	COG1960	acyl-CoA dehydrogenase activity
H7F24_03180	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F24_03185	COG0183	Belongs to the thiolase family
H7F24_03190	COG2181	nitrate reductase activity
H7F24_03190	COG0247	lactate metabolic process
H7F24_03195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F24_03200	COG4294	response to UV
H7F24_03210	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F24_03215	COG1132	(ABC) transporter
H7F24_03220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F24_03225	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F24_03230	COG0018	arginyl-trna synthetase
H7F24_03235	COG4506	Protein conserved in bacteria
H7F24_03245	COG0010	Belongs to the arginase family
H7F24_03250	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F24_03255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F24_03265	COG1994	Peptidase M50
H7F24_03270	COG1942	4-Oxalocrotonate Tautomerase
H7F24_03280	COG3465	dGTPase activity
H7F24_03285	COG1078	dGTPase activity
H7F24_03290	COG4844	belongs to the
H7F24_03340	COG5444	nuclease activity
H7F24_03370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7F24_03380	COG0280	phosphate acetyltransferase
H7F24_03390	COG2814	Major facilitator Superfamily
H7F24_03395	COG1522	sequence-specific DNA binding
H7F24_03400	COG2814	Major facilitator Superfamily
H7F24_03405	COG0077	Prephenate dehydratase
H7F24_03415	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_03420	COG0151	Belongs to the GarS family
H7F24_03425	COG0436	Aminotransferase
H7F24_03430	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_03435	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H7F24_03440	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7F24_03445	COG1088	dTDP-glucose 4,6-dehydratase activity
H7F24_03450	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H7F24_03455	COG3980	spore coat polysaccharide biosynthesis protein
H7F24_03460	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H7F24_03465	COG2089	acid synthase
H7F24_03470	COG0456	acetyltransferase
H7F24_03475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F24_03480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F24_03485	COG0463	Glycosyl transferase, family 2
H7F24_03505	COG2363	Small membrane protein
H7F24_03510	COG2233	PERMEase
H7F24_03520	COG1012	belongs to the aldehyde dehydrogenase family
H7F24_03525	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F24_03530	COG1216	Glycosyl transferase, family 2
H7F24_03540	COG0351	phosphomethylpyrimidine kinase
H7F24_03560	COG3964	amidohydrolase
H7F24_03565	COG1621	beta-fructofuranosidase activity
H7F24_03570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_03570	COG1263	PTS System
H7F24_03575	COG3711	transcriptional antiterminator
H7F24_03585	COG1404	Belongs to the peptidase S8 family
H7F24_03590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F24_03595	COG0778	Nitroreductase
H7F24_03600	COG0772	Belongs to the SEDS family
H7F24_03610	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F24_03615	COG1845	cytochrome c oxidase, subunit III
H7F24_03620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F24_03625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F24_03635	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H7F24_03640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F24_03645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H7F24_03660	COG2246	polysaccharide biosynthetic process
H7F24_03680	COG3162	membrane
H7F24_03685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F24_03695	COG0352	thiamine-phosphate diphosphorylase activity
H7F24_03700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H7F24_03705	COG0583	DNA-binding transcription factor activity
H7F24_03710	COG1380	Effector of murein hydrolase LrgA
H7F24_03715	COG1346	cytolysis
H7F24_03720	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7F24_03725	COG0346	lactoylglutathione lyase activity
H7F24_03735	COG0765	amino acid transport
H7F24_03740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F24_03745	COG0457	Tetratricopeptide repeat
H7F24_03755	COG2357	RelA SpoT domain protein
H7F24_03760	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F24_03765	COG1129	ABC transporter
H7F24_03775	COG3420	alginic acid biosynthetic process
H7F24_03780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F24_03790	COG1486	melibiose metabolic process
H7F24_03795	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F24_03800	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F24_03805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F24_03810	COG3711	transcriptional antiterminator
H7F24_03810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_03825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F24_03840	COG1595	DNA-templated transcription, initiation
H7F24_03850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7F24_03855	COG4988	ABC transporter
H7F24_03860	COG1294	oxidase, subunit
H7F24_03865	COG1271	oxidase subunit
H7F24_03885	COG4509	Sortase family
H7F24_03910	COG5386	Cell surface protein
H7F24_03915	COG5386	Cell surface protein
H7F24_03920	COG1733	regulation of RNA biosynthetic process
H7F24_03925	COG2514	catechol 2,3-dioxygenase activity
H7F24_03930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F24_03930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F24_03935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F24_03935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F24_03945	COG0726	polysaccharide deacetylase
H7F24_03950	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F24_03955	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F24_03960	COG2723	6-phospho-beta-galactosidase activity
H7F24_03965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F24_03970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_03970	COG3711	transcriptional antiterminator
H7F24_03995	COG1757	Na H antiporter
H7F24_04000	COG1027	Aspartate ammonia-lyase
H7F24_04005	COG0252	asparaginase activity
H7F24_04010	COG1396	sequence-specific DNA binding
H7F24_04035	COG4842	Belongs to the WXG100 family
H7F24_04040	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F24_04055	COG1737	Transcriptional regulator
H7F24_04060	COG2084	Dehydrogenase
H7F24_04070	COG2610	gluconate transmembrane transporter activity
H7F24_04075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F24_04085	COG2723	6-phospho-beta-galactosidase activity
H7F24_04090	COG2190	(PTS) system
H7F24_04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_04090	COG1263	PTS System
H7F24_04095	COG3711	transcriptional antiterminator
H7F24_04100	COG3878	Protein conserved in bacteria
H7F24_04110	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F24_04115	COG1122	ATPase activity
H7F24_04120	COG4721	ABC-type cobalt transport system, permease component
H7F24_04125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F24_04160	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F24_04165	COG0778	Nitroreductase
H7F24_04170	COG1846	Transcriptional regulator
H7F24_04175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H7F24_04180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F24_04185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F24_04190	COG2390	Transcriptional regulator
H7F24_04200	COG2755	lipolytic protein G-D-S-L family
H7F24_04200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F24_04220	COG0561	phosphatase activity
H7F24_04225	COG0789	Transcriptional regulator
H7F24_04230	COG0673	inositol 2-dehydrogenase activity
H7F24_04235	COG0840	transmembrane signaling receptor activity
H7F24_04240	COG1113	amino acid transport
H7F24_04245	COG4335	DNA alkylation repair
H7F24_04255	COG1070	Carbohydrate kinase
H7F24_04260	COG1737	Transcriptional regulator
H7F24_04290	COG0583	DNA-binding transcription factor activity
H7F24_04295	COG1609	Transcriptional regulator
H7F24_04300	COG2182	Extracellular solute-binding protein
H7F24_04305	COG1175	transmembrane transport
H7F24_04310	COG3833	ABC-type maltose transport systems, permease component
H7F24_04320	COG1874	Beta-galactosidase
H7F24_04325	COG2851	Citrate transporter
H7F24_04335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F24_04340	COG1131	(ABC) transporter
H7F24_04345	COG2824	Alkylphosphonate utilization operon protein PhnA
H7F24_04350	COG1929	Belongs to the glycerate kinase type-1 family
H7F24_04355	COG2610	gluconate transmembrane transporter activity
H7F24_04360	COG3835	regulator
H7F24_04365	COG1309	transcriptional regulator
H7F24_04370	COG2814	Major facilitator Superfamily
H7F24_04380	COG0577	efflux transmembrane transporter activity
H7F24_04380	COG1136	(ABC) transporter
H7F24_04390	COG0457	Tetratricopeptide repeat
H7F24_04395	COG3711	transcriptional antiterminator
H7F24_04400	COG2723	6-phospho-beta-galactosidase activity
H7F24_04405	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_04405	COG1263	PTS System
H7F24_04405	COG2190	(PTS) system
H7F24_04440	COG1113	amino acid transport
H7F24_04445	COG1609	Transcriptional regulator
H7F24_04450	COG2814	Major facilitator Superfamily
H7F24_04460	COG2814	Major facilitator Superfamily
H7F24_04480	COG5444	nuclease activity
H7F24_04490	COG2723	6-phospho-beta-galactosidase activity
H7F24_04500	COG2188	Transcriptional regulator
H7F24_04510	COG0384	phenazine biosynthesis protein PhzF
H7F24_04515	COG0583	DNA-binding transcription factor activity
H7F24_04540	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F24_04550	COG2814	Major facilitator Superfamily
H7F24_04555	COG0640	Transcriptional regulator
H7F24_04575	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7F24_04585	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F24_04595	COG4720	Psort location CytoplasmicMembrane, score
H7F24_04615	COG0456	acetyltransferase
H7F24_04620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F24_04625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7F24_04630	COG4853	Protein conserved in bacteria
H7F24_04635	COG4863	YycH protein
H7F24_04640	COG5002	protein histidine kinase activity
H7F24_04645	COG0745	RESPONSE REGULATOR receiver
H7F24_04670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F24_04680	COG2311	Membrane
H7F24_04685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7F24_04690	COG0346	lactoylglutathione lyase activity
H7F24_04695	COG0305	Participates in initiation and elongation during chromosome replication
H7F24_04720	COG2819	hydrolase of the alpha beta superfamily
H7F24_04725	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_04730	COG1169	isochorismate synthase
H7F24_04735	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7F24_04740	COG1535	isochorismatase
H7F24_04740	COG3433	isochorismatase activity
H7F24_04745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F24_04750	COG3251	PFAM MbtH domain protein
H7F24_04755	COG2207	Transcriptional regulator
H7F24_04755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F24_04760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F24_04765	COG2819	hydrolase of the alpha beta superfamily
H7F24_04770	COG3093	addiction module antidote protein HigA
H7F24_04775	COG2807	transmembrane transport
H7F24_04780	COG0359	binds to the 23S rRNA
H7F24_04785	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H7F24_04790	COG4241	membrane
H7F24_04795	COG1227	inorganic diphosphatase activity
H7F24_04805	COG1595	DNA-templated transcription, initiation
H7F24_04815	COG0753	catalase activity
H7F24_04820	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F24_04825	COG0400	carboxylic ester hydrolase activity
H7F24_04830	COG0346	lactoylglutathione lyase activity
H7F24_04835	COG1174	glycine betaine transport
H7F24_04840	COG1125	glycine betaine transport
H7F24_04840	COG0517	IMP dehydrogenase activity
H7F24_04845	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H7F24_04850	COG0629	single-stranded DNA binding
H7F24_04855	COG0360	Binds together with S18 to 16S ribosomal RNA
H7F24_04860	COG0012	GTP binding
H7F24_04865	COG4481	Protein conserved in bacteria
H7F24_04880	COG3949	Membrane
H7F24_04890	COG1475	DNA binding
H7F24_04895	COG1192	Involved in chromosome partitioning
H7F24_04905	COG1475	DNA binding
H7F24_04910	COG0357	Ribosomal RNA small subunit methyltransferase G
H7F24_04915	COG0445	tRNA wobble uridine modification
H7F24_04920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F24_04925	COG1847	R3H domain protein
H7F24_04930	COG0706	membrane insertase activity
H7F24_04935	COG0594	ribonuclease P activity
H7F24_04940	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H7F24_04945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F24_04950	COG0592	DNA-directed DNA polymerase activity
H7F24_04955	COG2501	S4 domain
H7F24_04960	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7F24_04970	COG0187	DNA topoisomerase II activity
H7F24_04975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F24_05010	COG0517	IMP dehydrogenase activity
H7F24_05010	COG0516	GMP reductase activity
H7F24_05015	COG1686	Belongs to the peptidase S11 family
H7F24_05020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F24_05025	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
H7F24_05030	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
H7F24_05035	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7F24_05040	COG0840	transmembrane signaling receptor activity
H7F24_05050	COG1428	Deoxynucleoside kinase
H7F24_05055	COG1428	Deoxynucleoside kinase
H7F24_05060	COG3858	chitin binding
H7F24_05060	COG1388	LysM domain
H7F24_05065	COG1335	isochorismatase
H7F24_05070	COG0590	tRNA wobble adenosine to inosine editing
H7F24_05080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7F24_05085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7F24_05090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7F24_05135	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H7F24_05140	COG3853	Toxic anion resistance protein (TelA)
H7F24_05145	COG1982	Orn Lys Arg decarboxylase major
H7F24_05150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7F24_05155	COG3870	Protein conserved in bacteria
H7F24_05160	COG1728	Protein conserved in bacteria
H7F24_05165	COG0470	DNA polymerase III
H7F24_05170	COG1774	PSP1 C-terminal conserved region
H7F24_05175	COG4467	Involved in initiation control of chromosome replication
H7F24_05180	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H7F24_05185	COG2827	Endonuclease containing a URI domain
H7F24_05190	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F24_05195	COG2002	toxin-antitoxin pair type II binding
H7F24_05200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F24_05200	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F24_05205	COG0084	hydrolase, TatD family'
H7F24_05210	COG3583	domain protein
H7F24_05210	COG3584	3D domain protein
H7F24_05215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F24_05220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F24_05230	COG4466	Protein conserved in bacteria
H7F24_05240	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7F24_05245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F24_05250	COG0251	oxidation-reduction process
H7F24_05255	COG2088	sporulation resulting in formation of a cellular spore
H7F24_05265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7F24_05270	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7F24_05275	COG0193	aminoacyl-tRNA hydrolase activity
H7F24_05285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7F24_05290	COG2002	toxin-antitoxin pair type II binding
H7F24_05295	COG2244	polysaccharide biosynthetic process
H7F24_05300	COG3956	TIGRFAM MazG family protein
H7F24_05305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7F24_05320	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7F24_05325	COG1098	S1 RNA binding domain
H7F24_05340	COG2208	phosphoserine phosphatase activity
H7F24_05345	COG2304	oxidoreductase activity
H7F24_05350	COG0515	serine threonine protein kinase
H7F24_05355	COG0037	tRNA processing
H7F24_05360	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H7F24_05365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F24_05370	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H7F24_05375	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7F24_05380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F24_05385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F24_05390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F24_05395	COG0512	Glutamine amidotransferase of anthranilate synthase
H7F24_05400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F24_05405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7F24_05410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7F24_05415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7F24_05420	COG1396	sequence-specific DNA binding
H7F24_05425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F24_05430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7F24_05510	COG4463	regulation of RNA biosynthetic process
H7F24_05515	COG3880	PFAM UvrB UvrC protein
H7F24_05520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
H7F24_05525	COG0542	response to heat
H7F24_05530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H7F24_05535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H7F24_05540	COG4956	integral membrane protein (PIN domain superfamily)
H7F24_05545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F24_05550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F24_05555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F24_05560	COG1045	serine acetyltransferase
H7F24_05565	COG0215	cysteine-tRNA ligase activity
H7F24_05570	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H7F24_05575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F24_05580	COG3688	RNA-binding protein containing a PIN domain
H7F24_05585	COG1595	DNA-templated transcription, initiation
H7F24_05590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F24_05595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F24_05600	COG0250	Participates in transcription elongation, termination and antitermination
H7F24_05610	COG0081	regulation of translation
H7F24_05615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H7F24_05620	COG0222	ribosome binding
H7F24_05625	COG2813	Specifically methylates the guanine in position
H7F24_05630	COG0085	RNA polymerase activity
H7F24_05635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7F24_05640	COG1358	cellular component organization or biogenesis
H7F24_05645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H7F24_05650	COG0049	tRNA binding
H7F24_05655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F24_05660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F24_05665	COG0596	Alpha beta hydrolase
H7F24_05675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7F24_05680	COG0088	Forms part of the polypeptide exit tunnel
H7F24_05685	COG0089	rRNA binding
H7F24_05690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7F24_05695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H7F24_05700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H7F24_05705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H7F24_05715	COG0255	Belongs to the universal ribosomal protein uL29 family
H7F24_05720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7F24_05725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7F24_05730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H7F24_05735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7F24_05740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F24_05745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7F24_05750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7F24_05755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7F24_05760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H7F24_05765	COG1841	ribosomal large subunit assembly
H7F24_05770	COG0200	Binds to the 23S rRNA
H7F24_05775	COG0201	protein transport
H7F24_05780	COG0563	adenylate kinase activity
H7F24_05785	COG0024	Methionine aminopeptidase
H7F24_05790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H7F24_05795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F24_05800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H7F24_05805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7F24_05810	COG0202	RNA polymerase activity
H7F24_05815	COG0203	ribosomal protein L17
H7F24_05820	COG1122	ATPase activity
H7F24_05825	COG1122	ATPase activity
H7F24_05830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F24_05835	COG0101	tRNA pseudouridine synthase activity
H7F24_05840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7F24_05845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7F24_05850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F24_05875	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F24_05880	COG0489	protein tyrosine kinase activity
H7F24_05890	COG2194	sulfuric ester hydrolase activity
H7F24_05895	COG0726	polysaccharide deacetylase
H7F24_05925	COG0659	secondary active sulfate transmembrane transporter activity
H7F24_05930	COG0385	Bile acid
H7F24_05935	COG3876	Protein conserved in bacteria
H7F24_05940	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F24_05945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F24_05950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_05950	COG1263	PTS System
H7F24_05955	COG1737	Transcriptional regulator
H7F24_05960	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H7F24_05995	COG1595	DNA-templated transcription, initiation
H7F24_06000	COG5662	AntiSigma factor
H7F24_06005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F24_06010	COG4856	YbbR-like protein
H7F24_06015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F24_06020	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7F24_06040	COG1131	(ABC) transporter
H7F24_06055	COG1131	(ABC) transporter
H7F24_06065	COG1413	lyase activity
H7F24_06075	COG2311	Membrane
H7F24_06095	COG1113	amino acid transport
H7F24_06100	COG0584	glycerophosphoryl diester phosphodiesterase
H7F24_06105	COG2271	Major facilitator Superfamily
H7F24_06115	COG1331	Highly conserved protein containing a thioredoxin domain
H7F24_06120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F24_06140	COG1937	Protein conserved in bacteria
H7F24_06145	COG2210	Belongs to the sulfur carrier protein TusA family
H7F24_06155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F24_06155	COG0425	Belongs to the sulfur carrier protein TusA family
H7F24_06160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F24_06160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F24_06165	COG0425	Belongs to the sulfur carrier protein TusA family
H7F24_06170	COG0730	response to heat
H7F24_06180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F24_06185	COG2814	Major facilitator Superfamily
H7F24_06195	COG1846	Transcriptional regulator
H7F24_06205	COG1683	Conserved Protein
H7F24_06215	COG0656	L-ascorbic acid biosynthetic process
H7F24_06220	COG1054	Belongs to the UPF0176 family
H7F24_06225	COG0531	amino acid
H7F24_06235	COG3711	transcriptional antiterminator
H7F24_06240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_06240	COG2190	(PTS) system
H7F24_06240	COG1263	PTS System
H7F24_06245	COG2723	6-phospho-beta-galactosidase activity
H7F24_06265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_06265	COG3711	transcriptional antiterminator
H7F24_06270	COG1940	carbohydrate kinase activity
H7F24_06275	COG0383	alpha-mannosidase activity
H7F24_06280	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_06285	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_06295	COG1404	Belongs to the peptidase S8 family
H7F24_06310	COG0833	amino acid
H7F24_06315	COG2040	homocysteine
H7F24_06320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F24_06325	COG1695	Transcriptional regulator
H7F24_06340	COG2814	Major facilitator Superfamily
H7F24_06345	COG0456	acetyltransferase
H7F24_06360	COG1404	Belongs to the peptidase S8 family
H7F24_06370	COG1309	transcriptional regulator
H7F24_06375	COG1917	Cupin 2, conserved barrel domain protein
H7F24_06380	COG1063	alcohol dehydrogenase
H7F24_06385	COG1846	Transcriptional regulator
H7F24_06390	COG0318	PFAM AMP-dependent synthetase and ligase
H7F24_06395	COG0531	amino acid
H7F24_06405	COG0596	Alpha beta hydrolase
H7F24_06410	COG1115	amino acid carrier protein
H7F24_06415	COG2066	Belongs to the glutaminase family
H7F24_06420	COG4191	Histidine kinase
H7F24_06425	COG0784	Response regulator, receiver
H7F24_06430	COG1405	negative regulation of cell septum assembly
H7F24_06430	COG3012	SEC-C Motif Domain Protein
H7F24_06440	COG2197	response regulator
H7F24_06445	COG4585	Histidine kinase
H7F24_06455	COG0667	Aldo Keto reductase
H7F24_06460	COG3290	protein histidine kinase activity
H7F24_06465	COG3279	Response regulator of the LytR AlgR family
H7F24_06470	COG4555	ABC transporter
H7F24_06475	COG1668	transmembrane transport
H7F24_06490	COG3773	Cell wall hydrolase
H7F24_06495	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_06505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F24_06510	COG2310	stress, protein
H7F24_06515	COG2310	stress, protein
H7F24_06520	COG2310	stress, protein
H7F24_06525	COG0861	Integral membrane protein TerC family
H7F24_06555	COG3853	Toxic anion resistance protein (TelA)
H7F24_06560	COG4175	Glycine betaine
H7F24_06560	COG0517	IMP dehydrogenase activity
H7F24_06565	COG4176	ABC-type proline glycine betaine transport system permease component
H7F24_06570	COG2113	Glycine betaine
H7F24_06585	COG1473	amidohydrolase
H7F24_06590	COG1288	antiporter activity
H7F24_06595	COG0039	L-malate dehydrogenase activity
H7F24_06600	COG1620	l-lactate permease
H7F24_06605	COG1609	Transcriptional regulator
H7F24_06610	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F24_06615	COG0561	phosphatase activity
H7F24_06620	COG0673	inositol 2-dehydrogenase activity
H7F24_06625	COG0738	Major facilitator superfamily
H7F24_06630	COG1280	lysine exporter protein (LysE YggA)
H7F24_06640	COG3403	YqcI/YcgG family
H7F24_06645	COG1113	amino acid transport
H7F24_06650	COG3665	Urea carboxylase-associated protein
H7F24_06655	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7F24_06665	COG1012	belongs to the aldehyde dehydrogenase family
H7F24_06670	COG0710	3-dehydroquinate dehydratase activity
H7F24_06675	COG0028	Belongs to the TPP enzyme family
H7F24_06685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7F24_06690	COG2271	Major facilitator Superfamily
H7F24_06705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F24_06710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F24_06715	COG1609	Transcriptional regulator
H7F24_06720	COG0477	Major facilitator Superfamily
H7F24_06725	COG2226	methyltransferase
H7F24_06730	COG0583	DNA-binding transcription factor activity
H7F24_06735	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F24_06740	COG3458	cephalosporin-C deacetylase activity
H7F24_06750	COG3541	Predicted nucleotidyltransferase
H7F24_06755	COG0506	proline dehydrogenase activity
H7F24_06760	COG1012	belongs to the aldehyde dehydrogenase family
H7F24_06765	COG2508	Transcriptional regulator
H7F24_06770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F24_06775	COG0765	amino acid transport
H7F24_06780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F24_06790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F24_06795	COG1522	sequence-specific DNA binding
H7F24_06800	COG2746	aminoglycoside 3-N-acetyltransferase activity
H7F24_06810	COG3290	protein histidine kinase activity
H7F24_06810	COG0840	transmembrane signaling receptor activity
H7F24_06815	COG3209	COG3209 Rhs family protein
H7F24_06835	COG3842	ATPase activity
H7F24_06850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F24_06855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F24_06860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F24_06875	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7F24_06880	COG0697	spore germination
H7F24_06885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F24_06900	COG2364	Membrane
H7F24_06905	COG1126	abc transporter atp-binding protein
H7F24_06910	COG0765	amino acid transport
H7F24_06915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F24_06920	COG0833	amino acid
H7F24_06930	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_06935	COG1312	Catalyzes the dehydration of D-mannonate
H7F24_06940	COG1802	Transcriptional regulator
H7F24_06945	COG0673	inositol 2-dehydrogenase activity
H7F24_06955	COG1904	glucuronate isomerase
H7F24_06960	COG3104	oligopeptide transport
H7F24_06965	COG5434	Belongs to the glycosyl hydrolase 28 family
H7F24_06970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F24_06975	COG0456	acetyltransferase
H7F24_06980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F24_06985	COG0765	amino acid transport
H7F24_06990	COG1126	abc transporter atp-binding protein
H7F24_06995	COG1473	amidohydrolase
H7F24_07000	COG2079	MmgE PrpD family protein
H7F24_07005	COG0745	RESPONSE REGULATOR receiver
H7F24_07010	COG3850	Histidine kinase
H7F24_07010	COG5002	protein histidine kinase activity
H7F24_07015	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_07020	COG0527	aspartate kinase activity
H7F24_07025	COG2814	Major facilitator Superfamily
H7F24_07030	COG1309	transcriptional regulator
H7F24_07040	COG0640	Transcriptional regulator
H7F24_07045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F24_07050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F24_07055	COG0531	amino acid
H7F24_07060	COG1012	belongs to the aldehyde dehydrogenase family
H7F24_07065	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F24_07070	COG4549	nuclear export factor GLE1
H7F24_07075	COG1276	copper resistance
H7F24_07075	COG2372	response to copper ion
H7F24_07080	COG2213	PTS system mannitol-specific
H7F24_07085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_07090	COG0246	Mannitol dehydrogenase
H7F24_07095	COG0840	transmembrane signaling receptor activity
H7F24_07120	COG0346	lactoylglutathione lyase activity
H7F24_07130	COG0561	phosphatase activity
H7F24_07135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F24_07140	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F24_07145	COG4336	lyase activity
H7F24_07150	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F24_07155	COG1984	allophanate hydrolase subunit 2
H7F24_07160	COG1414	Transcriptional regulator
H7F24_07165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F24_07170	COG2755	lipolytic protein G-D-S-L family
H7F24_07180	COG3711	transcriptional antiterminator
H7F24_07185	COG2226	methyltransferase
H7F24_07190	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_07195	COG3871	stress protein (general stress protein 26)
H7F24_07220	COG2814	Major facilitator Superfamily
H7F24_07225	COG1802	Transcriptional regulator
H7F24_07230	COG2207	Transcriptional regulator
H7F24_07230	COG1917	Cupin 2, conserved barrel domain protein
H7F24_07235	COG0697	spore germination
H7F24_07240	COG0473	3-isopropylmalate dehydrogenase activity
H7F24_07245	COG0551	DNA topoisomerase type I activity
H7F24_07245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F24_07250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H7F24_07255	COG3706	GGDEF domain
H7F24_07260	COG5298	Protein conserved in bacteria
H7F24_07265	COG1215	transferase activity, transferring glycosyl groups
H7F24_07275	COG0531	amino acid
H7F24_07280	COG0028	Belongs to the TPP enzyme family
H7F24_07285	COG5444	nuclease activity
H7F24_07310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F24_07315	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F24_07320	COG2261	transglycosylase associated protein
H7F24_07325	COG2217	Heavy metal translocating P-type atpase
H7F24_07330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F24_07335	COG3290	protein histidine kinase activity
H7F24_07340	COG4565	transcriptional regulatory protein
H7F24_07345	COG1301	dicarboxylic acid transport
H7F24_07350	COG0628	permease
H7F24_07355	COG1301	dicarboxylic acid transport
H7F24_07360	COG1131	(ABC) transporter
H7F24_07365	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F24_07380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_07385	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F24_07390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F24_07405	COG0513	Belongs to the DEAD box helicase family
H7F24_07410	COG3402	PFAM membrane-flanked domain
H7F24_07415	COG3428	Bacterial PH domain
H7F24_07420	COG0705	Rhomboid family
H7F24_07425	COG0736	holo-[acyl-carrier-protein] synthase activity
H7F24_07430	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7F24_07435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F24_07440	COG0864	Transcriptional regulator
H7F24_07445	COG2337	Toxic component of a toxin-antitoxin (TA) module
H7F24_07450	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_07455	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_07460	COG2172	sigma factor antagonist activity
H7F24_07465	COG2208	phosphoserine phosphatase activity
H7F24_07470	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_07475	COG2172	sigma factor antagonist activity
H7F24_07480	COG1191	sigma factor activity
H7F24_07485	COG2208	phosphoserine phosphatase activity
H7F24_07490	COG2183	response to ionizing radiation
H7F24_07500	COG3091	SprT-like family
H7F24_07505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F24_07510	COG0022	dehydrogenase e1 component
H7F24_07515	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F24_07520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F24_07525	COG3284	Transcriptional regulator
H7F24_07565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H7F24_07575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F24_07580	COG0456	acetyltransferase
H7F24_07580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7F24_07585	COG1278	Cold shock
H7F24_07590	COG1404	Belongs to the peptidase S8 family
H7F24_07605	COG0789	Transcriptional regulator
H7F24_07615	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F24_07640	COG0477	Major facilitator Superfamily
H7F24_07645	COG0657	acetylesterase activity
H7F24_07650	COG4221	oxidoreductase activity
H7F24_07660	COG0252	asparaginase activity
H7F24_07680	COG2814	Major facilitator Superfamily
H7F24_07685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F24_07715	COG1309	transcriptional regulator
H7F24_07720	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F24_07725	COG1846	Transcriptional regulator
H7F24_07730	COG0778	Nitroreductase
H7F24_07745	COG1396	sequence-specific DNA binding
H7F24_07765	COG4122	O-methyltransferase activity
H7F24_07775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7F24_07780	COG0697	spore germination
H7F24_07790	COG1301	dicarboxylic acid transport
H7F24_07830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7F24_07835	COG0802	atpase or kinase
H7F24_07840	COG1214	PFAM Peptidase M22, glycoprotease
H7F24_07845	COG0456	acetyltransferase
H7F24_07850	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7F24_07855	COG0488	(ABC) transporter
H7F24_07860	COG0315	cyclic pyranopterin monophosphate synthase activity
H7F24_07865	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H7F24_07870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F24_07875	COG0805	protein transport
H7F24_07890	COG1266	CAAX protease self-immunity
H7F24_07895	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H7F24_07900	COG0459	protein refolding
H7F24_07975	COG1846	Transcriptional regulator
H7F24_07980	COG0456	acetyltransferase
H7F24_07985	COG2808	Putative FMN-binding domain
H7F24_08015	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F24_08020	COG0823	Involved in the tonB-independent uptake of proteins
H7F24_08030	COG2132	Multicopper oxidase
H7F24_08035	COG1113	amino acid transport
H7F24_08040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F24_08045	COG0714	Associated with various cellular activities
H7F24_08050	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H7F24_08055	COG1305	Transglutaminase-like
H7F24_08060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F24_08060	COG0519	Catalyzes the synthesis of GMP from XMP
H7F24_08065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7F24_08075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F24_08080	COG2207	Transcriptional regulator
H7F24_08095	COG1404	Belongs to the peptidase S8 family
H7F24_08110	COG2814	Major facilitator Superfamily
H7F24_08115	COG0583	DNA-binding transcription factor activity
H7F24_08120	COG2252	PERMEase
H7F24_08135	COG3064	Membrane
H7F24_08140	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
H7F24_08150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7F24_08155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7F24_08160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7F24_08165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7F24_08170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F24_08175	COG0047	phosphoribosylformylglycinamidine synthase activity
H7F24_08180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F24_08185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H7F24_08190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7F24_08195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F24_08200	COG0138	bifunctional purine biosynthesis protein purh
H7F24_08205	COG0151	Belongs to the GarS family
H7F24_08225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F24_08230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7F24_08235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F24_08240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F24_08250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F24_08255	COG4496	protein, YerC YecD
H7F24_08260	COG0069	glutamate synthase activity
H7F24_08275	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H7F24_08280	COG0210	DNA helicase
H7F24_08285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F24_08290	COG4851	CamS sex pheromone cAM373 precursor
H7F24_08305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F24_08320	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F24_08335	COG1960	acyl-CoA dehydrogenase activity
H7F24_08365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F24_08370	COG1785	Belongs to the alkaline phosphatase family
H7F24_08375	COG1285	pathogenesis
H7F24_08380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F24_08385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F24_08390	COG0154	amidase activity
H7F24_08395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F24_08400	COG1309	transcriptional regulator
H7F24_08405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F24_08410	COG1957	nucleoside hydrolase
H7F24_08415	COG1597	lipid kinase activity
H7F24_08420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F24_08425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F24_08435	COG1737	Transcriptional regulator
H7F24_08440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_08440	COG1263	PTS System
H7F24_08445	COG1486	melibiose metabolic process
H7F24_08455	COG1959	2 iron, 2 sulfur cluster binding
H7F24_08460	COG0492	ferredoxin-NADP+ reductase activity
H7F24_08475	COG1486	melibiose metabolic process
H7F24_08485	COG2211	Major facilitator Superfamily
H7F24_08515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7F24_08520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F24_08525	COG1442	glycosyl transferase family 8
H7F24_08530	COG1216	Glycosyl transferase, family 2
H7F24_08535	COG1442	glycosyl transferase family 8
H7F24_08540	COG2223	nitrite transmembrane transporter activity
H7F24_08550	COG0471	metal ion transport
H7F24_08565	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F24_08580	COG0531	amino acid
H7F24_08585	COG0463	Glycosyl transferase, family 2
H7F24_08590	COG0488	(ABC) transporter
H7F24_08595	COG1469	GTP cyclohydrolase I activity
H7F24_08600	COG0789	Transcriptional regulator
H7F24_08605	COG2814	Major facilitator Superfamily
H7F24_08610	COG0488	(ABC) transporter
H7F24_08615	COG0513	Belongs to the DEAD box helicase family
H7F24_08630	COG2130	NADP-dependent
H7F24_08650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F24_08650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F24_08655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7F24_08665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F24_08665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F24_08675	COG3290	protein histidine kinase activity
H7F24_08680	COG4565	transcriptional regulatory protein
H7F24_08685	COG3181	Tripartite tricarboxylate transporter family receptor
H7F24_08690	COG2851	Citrate transporter
H7F24_08700	COG3479	Phenolic acid decarboxylase
H7F24_08705	COG1695	Transcriptional regulator
H7F24_08710	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H7F24_08715	COG1254	Belongs to the acylphosphatase family
H7F24_08720	COG2258	MOSC domain
H7F24_08735	COG0024	Methionine aminopeptidase
H7F24_08740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_08740	COG1263	PTS System
H7F24_08745	COG3739	integral membrane protein
H7F24_08760	COG1368	sulfuric ester hydrolase activity
H7F24_08765	COG0076	glutamate decarboxylase activity
H7F24_08770	COG0840	transmembrane signaling receptor activity
H7F24_08780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_08780	COG1263	PTS System
H7F24_08785	COG0366	Alpha amylase catalytic
H7F24_08790	COG2188	Transcriptional regulator
H7F24_08800	COG0737	Belongs to the 5'-nucleotidase family
H7F24_08805	COG0693	protein deglycase activity
H7F24_08810	COG4840	Belongs to the UPF0435 family
H7F24_08815	COG1115	amino acid carrier protein
H7F24_08820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F24_08825	COG4980	gas vesicle protein
H7F24_08830	COG1295	ribonuclease BN
H7F24_08835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F24_08840	COG0477	Major facilitator Superfamily
H7F24_08850	COG0387	Pfam Sodium calcium exchanger
H7F24_08860	COG0217	transcriptional regulatory protein
H7F24_08865	COG0668	transmembrane transport
H7F24_08870	COG0535	radical SAM domain protein
H7F24_08880	COG0726	polysaccharide deacetylase
H7F24_08885	COG0598	Magnesium transport protein CorA
H7F24_08895	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H7F24_08900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F24_08915	COG0789	Transcriptional regulator
H7F24_08920	COG2814	Major facilitator Superfamily
H7F24_08930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F24_08975	COG2076	Multidrug Resistance protein
H7F24_08980	COG2076	Multidrug Resistance protein
H7F24_08985	COG1309	transcriptional regulator
H7F24_08995	COG4637	Psort location Cytoplasmic, score
H7F24_09000	COG2755	lipolytic protein G-D-S-L family
H7F24_09005	COG0492	ferredoxin-NADP+ reductase activity
H7F24_09010	COG1742	UPF0060 membrane protein
H7F24_09025	COG2318	DinB family
H7F24_09035	COG1846	Transcriptional regulator
H7F24_09040	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H7F24_09040	COG0392	lysyltransferase activity
H7F24_09060	COG0778	Nitroreductase
H7F24_09075	COG1090	epimerase
H7F24_09080	COG2137	regulation of response to DNA damage stimulus
H7F24_09105	COG0463	Glycosyl transferase, family 2
H7F24_09110	COG4485	Bacterial membrane protein, YfhO
H7F24_09120	COG2140	Oxalate decarboxylase
H7F24_09130	COG1191	sigma factor activity
H7F24_09140	COG1988	membrane-bound metal-dependent
H7F24_09145	COG1194	a g-specific adenine glycosylase
H7F24_09155	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_09170	COG3557	Belongs to the UPF0374 family
H7F24_09175	COG1132	(ABC) transporter
H7F24_09180	COG0444	Belongs to the ABC transporter superfamily
H7F24_09185	COG4608	Belongs to the ABC transporter superfamily
H7F24_09190	COG0747	negative chemotaxis
H7F24_09195	COG0601	transmembrane transport
H7F24_09200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F24_09205	COG4129	membrane
H7F24_09210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F24_09215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F24_09220	COG0735	belongs to the Fur family
H7F24_09370	COG1368	sulfuric ester hydrolase activity
H7F24_09375	COG0681	Belongs to the peptidase S26 family
H7F24_09380	COG2873	o-acetylhomoserine
H7F24_09390	COG1116	anion transmembrane transporter activity
H7F24_09395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F24_09400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F24_09415	COG4152	abc transporter atp-binding protein
H7F24_09445	COG3382	B3 4 domain protein
H7F24_09450	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7F24_09460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7F24_09465	COG2766	serine protein kinase
H7F24_09470	COG2718	Belongs to the UPF0229 family
H7F24_09475	COG1566	PFAM secretion protein HlyD family protein
H7F24_09480	COG2814	Major facilitator Superfamily
H7F24_09485	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F24_09495	COG1278	Cold shock
H7F24_09500	COG3706	GGDEF domain
H7F24_09525	COG5577	PFAM Coat F domain
H7F24_09530	COG5002	protein histidine kinase activity
H7F24_09535	COG1525	nuclease
H7F24_09535	COG4085	toxin activity
H7F24_09535	COG0737	Belongs to the 5'-nucleotidase family
H7F24_09540	COG3764	Sortase (surface protein transpeptidase)
H7F24_09545	COG0564	pseudouridine synthase activity
H7F24_09555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F24_09560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F24_09560	COG3153	acetyltransferase
H7F24_09575	COG3835	regulator
H7F24_09580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F24_09585	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H7F24_09590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7F24_09595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F24_09600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7F24_09605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F24_09610	COG2203	Gaf domain
H7F24_09610	COG4585	Histidine kinase
H7F24_09615	COG2197	response regulator
H7F24_09630	COG0753	catalase activity
H7F24_09635	COG1959	2 iron, 2 sulfur cluster binding
H7F24_09640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F24_09640	COG1017	nitric oxide dioxygenase activity
H7F24_09645	COG2719	SpoVR family
H7F24_09650	COG1785	Belongs to the alkaline phosphatase family
H7F24_09655	COG0791	NLP P60 protein
H7F24_09655	COG1388	LysM domain
H7F24_09660	COG0531	amino acid
H7F24_09675	COG1595	DNA-templated transcription, initiation
H7F24_09680	COG0204	Acyl-transferase
H7F24_09685	COG1253	flavin adenine dinucleotide binding
H7F24_09690	COG0789	Transcriptional regulator
H7F24_09695	COG1253	flavin adenine dinucleotide binding
H7F24_09705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F24_09710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F24_09715	COG0584	glycerophosphoryl diester phosphodiesterase
H7F24_09725	COG0668	transmembrane transport
H7F24_09730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7F24_09735	COG0726	polysaccharide deacetylase
H7F24_09740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F24_09745	COG0589	response to stress
H7F24_09750	COG1132	(ABC) transporter
H7F24_09755	COG1132	(ABC) transporter
H7F24_09765	COG0702	epimerase
H7F24_09775	COG3842	ATPase activity
H7F24_09780	COG2508	Transcriptional regulator
H7F24_09790	COG0189	ligase activity
H7F24_09795	COG0189	ligase activity
H7F24_09800	COG4399	Belongs to the UPF0754 family
H7F24_09805	COG3679	Belongs to the UPF0342 family
H7F24_09810	COG0561	phosphatase activity
H7F24_09815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F24_09825	COG0475	glutathione-regulated potassium exporter activity
H7F24_09830	COG0490	domain, Protein
H7F24_09840	COG1024	Enoyl-CoA hydratase
H7F24_09850	COG0420	3'-5' exonuclease activity
H7F24_09855	COG4717	serine-type aminopeptidase activity
H7F24_09860	COG3481	metal-dependent phosphohydrolase, HD sub domain
H7F24_09870	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F24_09895	COG1846	Transcriptional regulator
H7F24_09900	COG4980	gas vesicle protein
H7F24_09915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7F24_09920	COG0537	adenosine 5'-monophosphoramidase activity
H7F24_09925	COG1131	(ABC) transporter
H7F24_09930	COG4473	ABC transporter
H7F24_09940	COG1473	amidohydrolase
H7F24_09950	COG2329	Antibiotic biosynthesis monooxygenase
H7F24_09955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F24_09960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7F24_09965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F24_09970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H7F24_09975	COG1309	transcriptional regulator
H7F24_09980	COG1511	domain protein
H7F24_09985	COG1363	Peptidase, m42
H7F24_09990	COG1301	dicarboxylic acid transport
H7F24_10000	COG1234	tRNA 3'-trailer cleavage
H7F24_10005	COG0095	Lipoate-protein ligase
H7F24_10010	COG0318	PFAM AMP-dependent synthetase and ligase
H7F24_10020	COG0501	Belongs to the peptidase M48B family
H7F24_10025	COG1404	Belongs to the peptidase S8 family
H7F24_10030	COG0406	alpha-ribazole phosphatase activity
H7F24_10035	COG0840	transmembrane signaling receptor activity
H7F24_10040	COG0723	plastoquinol--plastocyanin reductase activity
H7F24_10040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F24_10045	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_10055	COG4903	ComK protein
H7F24_10065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F24_10070	COG2814	Major facilitator Superfamily
H7F24_10075	COG2732	(Barnase) inhibitor
H7F24_10080	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F24_10085	COG4605	iron ion homeostasis
H7F24_10090	COG4604	ABC transporter, ATP-binding protein
H7F24_10095	COG4607	ABC-type enterochelin transport system periplasmic component
H7F24_10100	COG1316	TRANSCRIPTIONal
H7F24_10110	COG0398	Pfam SNARE associated Golgi protein
H7F24_10115	COG0681	Belongs to the peptidase S26 family
H7F24_10120	COG3180	Ammonia monooxygenase
H7F24_10130	COG0501	Belongs to the peptidase M48B family
H7F24_10135	COG2259	Doxx family
H7F24_10140	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H7F24_10145	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H7F24_10150	COG1074	ATP-dependent DNA helicase activity
H7F24_10155	COG0420	3'-5' exonuclease activity
H7F24_10160	COG0419	ATPase involved in DNA repair
H7F24_10165	COG1403	HNH endonuclease
H7F24_10205	COG5337	Spore coat protein CotH
H7F24_10215	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F24_10230	COG0367	asparagine synthase
H7F24_10245	COG1562	ergosterol biosynthetic process
H7F24_10250	COG0534	Mate efflux family protein
H7F24_10255	COG1917	Cupin 2, conserved barrel domain protein
H7F24_10255	COG2207	Transcriptional regulator
H7F24_10285	COG0076	glutamate decarboxylase activity
H7F24_10315	COG1410	methionine synthase
H7F24_10315	COG0646	methionine synthase
H7F24_10320	COG0646	methionine synthase
H7F24_10320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7F24_10325	COG1666	GTP binding
H7F24_10330	COG2996	Protein conserved in bacteria
H7F24_10335	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F24_10340	COG0840	transmembrane signaling receptor activity
H7F24_10345	COG1307	EDD domain protein, DegV family
H7F24_10350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F24_10370	COG0561	phosphatase activity
H7F24_10375	COG1073	alpha beta
H7F24_10380	COG2151	metal-sulfur cluster biosynthetic enzyme
H7F24_10385	COG0277	FAD linked oxidase domain protein
H7F24_10390	COG2271	Major facilitator Superfamily
H7F24_10395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F24_10400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7F24_10405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H7F24_10410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F24_10415	COG0505	Belongs to the CarA family
H7F24_10420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F24_10425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F24_10435	COG2814	Major facilitator Superfamily
H7F24_10445	COG2267	carboxylic ester hydrolase activity
H7F24_10455	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F24_10470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F24_10475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F24_10480	COG5504	Zn-dependent protease
H7F24_10485	COG0444	Belongs to the ABC transporter superfamily
H7F24_10490	COG4608	Belongs to the ABC transporter superfamily
H7F24_10500	COG0601	transmembrane transport
H7F24_10505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F24_10525	COG0180	Tryptophanyl-tRNA synthetase
H7F24_10535	COG4166	transmembrane transport
H7F24_10540	COG0601	transmembrane transport
H7F24_10545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F24_10550	COG0444	Belongs to the ABC transporter superfamily
H7F24_10555	COG4608	Belongs to the ABC transporter superfamily
H7F24_10565	COG0456	acetyltransferase
H7F24_10570	COG1393	Belongs to the ArsC family
H7F24_10575	COG0861	Integral membrane protein TerC family
H7F24_10580	COG4862	establishment of competence for transformation
H7F24_10585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F24_10595	COG1164	Oligoendopeptidase f
H7F24_10605	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F24_10610	COG2346	COG2346, Truncated hemoglobins
H7F24_10615	COG0741	lytic transglycosylase activity
H7F24_10620	COG4116	CYTH
H7F24_10630	COG2357	RelA SpoT domain protein
H7F24_10635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F24_10640	COG0564	pseudouridine synthase activity
H7F24_10645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7F24_10650	COG0569	domain protein
H7F24_10650	COG0475	glutathione-regulated potassium exporter activity
H7F24_10655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F24_10660	COG0352	thiamine-phosphate diphosphorylase activity
H7F24_10670	COG2104	thiamine diphosphate biosynthetic process
H7F24_10675	COG2022	thiamine diphosphate biosynthetic process
H7F24_10680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F24_10685	COG0351	phosphomethylpyrimidine kinase
H7F24_10690	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7F24_10745	COG0210	DNA helicase
H7F24_10760	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F24_10765	COG2382	esterase
H7F24_10770	COG0626	cystathionine gamma-synthase activity
H7F24_10775	COG0626	cystathionine gamma-synthase activity
H7F24_10925	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H7F24_10955	COG1780	Probably involved in ribonucleotide reductase function
H7F24_10960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F24_10970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F24_10990	COG0756	dUTP diphosphatase activity
H7F24_11000	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
H7F24_11085	COG0582	viral genome integration into host DNA
H7F24_11160	COG1705	Flagellar rod assembly protein muramidase FlgJ
H7F24_11195	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F24_11195	COG3409	Peptidoglycan-binding domain 1 protein
H7F24_11230	COG0457	Tetratricopeptide repeat
H7F24_11235	COG1733	regulation of RNA biosynthetic process
H7F24_11245	COG0604	alcohol dehydrogenase
H7F24_11255	COG0825	malonyl-CoA metabolic process
H7F24_11265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F24_11315	COG0457	Tetratricopeptide repeat
H7F24_11345	COG0583	DNA-binding transcription factor activity
H7F24_11350	COG2807	transmembrane transport
H7F24_11370	COG0457	Tetratricopeptide repeat
H7F24_11400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F24_11420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F24_11425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F24_11430	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F24_11450	COG4195	phage-related replication protein
H7F24_11455	COG2856	Zn peptidase
H7F24_11460	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F24_11460	COG3409	Peptidoglycan-binding domain 1 protein
H7F24_11480	COG0306	phosphate transporter
H7F24_11485	COG1392	Phosphate transport regulator
H7F24_11495	COG0405	Gamma-glutamyltransferase
H7F24_11500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7F24_11510	COG4208	sulfate ABC transporter
H7F24_11515	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7F24_11525	COG3775	system Galactitol-specific IIC component
H7F24_11540	COG1063	alcohol dehydrogenase
H7F24_11545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F24_11550	COG0022	dehydrogenase e1 component
H7F24_11550	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F24_11555	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F24_11560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F24_11565	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_11570	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_11575	COG2390	Transcriptional regulator
H7F24_11585	COG0531	amino acid
H7F24_11590	COG0346	lactoylglutathione lyase activity
H7F24_11595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F24_11600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F24_11605	COG2362	D-Aminopeptidase
H7F24_11610	COG0601	transmembrane transport
H7F24_11615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F24_11620	COG0444	Belongs to the ABC transporter superfamily
H7F24_11625	COG4166	transmembrane transport
H7F24_11630	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F24_11635	COG4948	Mandelate Racemase Muconate Lactonizing
H7F24_11640	COG0791	NLP P60 protein
H7F24_11645	COG4608	Belongs to the ABC transporter superfamily
H7F24_11650	COG1834	amidinotransferase
H7F24_11655	COG1607	acyl-coa hydrolase
H7F24_11660	COG1695	Transcriptional regulator
H7F24_11675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F24_11690	COG2076	Multidrug Resistance protein
H7F24_11695	COG2076	Multidrug Resistance protein
H7F24_11705	COG0788	formyltetrahydrofolate deformylase activity
H7F24_11710	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F24_11715	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F24_11720	COG0457	Tetratricopeptide repeat
H7F24_11730	COG1764	response to oxidative stress
H7F24_11735	COG1846	Transcriptional regulator
H7F24_11740	COG1764	response to oxidative stress
H7F24_11745	COG0590	tRNA wobble adenosine to inosine editing
H7F24_11750	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F24_11755	COG1404	Belongs to the peptidase S8 family
H7F24_11760	COG0745	RESPONSE REGULATOR receiver
H7F24_11765	COG3850	Histidine kinase
H7F24_11765	COG5002	protein histidine kinase activity
H7F24_11770	COG3212	peptidase
H7F24_11775	COG3212	peptidase
H7F24_11785	COG2239	Acts as a magnesium transporter
H7F24_11795	COG0789	Transcriptional regulator
H7F24_11815	COG1846	Transcriptional regulator
H7F24_11820	COG5001	Diguanylate cyclase
H7F24_11820	COG3300	MHYT domain
H7F24_11825	COG0586	Pfam SNARE associated Golgi protein
H7F24_11830	COG0861	Integral membrane protein TerC family
H7F24_11835	COG1191	sigma factor activity
H7F24_11855	COG0501	Belongs to the peptidase M48B family
H7F24_11860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F24_11865	COG2323	membrane
H7F24_11880	COG3594	Acyltransferase
H7F24_11885	COG5002	protein histidine kinase activity
H7F24_11890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F24_11900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H7F24_11905	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H7F24_11910	COG0436	Aminotransferase
H7F24_11915	COG1850	ribulose-bisphosphate carboxylase activity
H7F24_11925	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H7F24_11935	COG3852	Histidine kinase
H7F24_11940	COG1846	Transcriptional regulator
H7F24_11945	COG1360	Flagellar Motor Protein
H7F24_11950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F24_11955	COG0542	response to heat
H7F24_11960	COG3949	Membrane
H7F24_11965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7F24_11970	COG0720	synthase
H7F24_11975	COG0602	queuosine metabolic process
H7F24_11980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F24_11985	COG1733	regulation of RNA biosynthetic process
H7F24_11990	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_12000	COG4873	Protein conserved in bacteria
H7F24_12010	COG3773	Cell wall hydrolase
H7F24_12015	COG2244	polysaccharide biosynthetic process
H7F24_12020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_12025	COG2217	Heavy metal translocating P-type atpase
H7F24_12030	COG0006	proline dipeptidase activity
H7F24_12040	COG1609	Transcriptional regulator
H7F24_12045	COG3711	transcriptional antiterminator
H7F24_12050	COG1263	PTS System
H7F24_12050	COG2190	(PTS) system
H7F24_12050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_12055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_12060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F24_12070	COG1533	DNA photolyase activity
H7F24_12075	COG0840	transmembrane signaling receptor activity
H7F24_12085	COG2084	Dehydrogenase
H7F24_12090	COG2340	Cysteine-rich secretory protein family
H7F24_12095	COG0768	penicillin binding
H7F24_12100	COG4191	Histidine kinase
H7F24_12105	COG0436	Aminotransferase
H7F24_12110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F24_12120	COG1714	RDD family
H7F24_12130	COG0784	Response regulator, receiver
H7F24_12130	COG0835	chemotaxis
H7F24_12140	COG2207	Transcriptional regulator
H7F24_12140	COG1917	Cupin 2, conserved barrel domain protein
H7F24_12145	COG0697	spore germination
H7F24_12155	COG2814	Major facilitator Superfamily
H7F24_12160	COG1376	ErfK ybiS ycfS ynhG family protein
H7F24_12165	COG1408	metallophosphoesterase
H7F24_12170	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_12175	COG2200	EAL domain
H7F24_12180	COG3546	catalase activity
H7F24_12185	COG4703	Protein of unknown function (DUF1797)
H7F24_12190	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H7F24_12200	COG0517	IMP dehydrogenase activity
H7F24_12205	COG0583	DNA-binding transcription factor activity
H7F24_12210	COG0716	FMN binding
H7F24_12220	COG0716	FMN binding
H7F24_12225	COG2171	N-acyltransferase activity
H7F24_12230	COG1473	amidohydrolase
H7F24_12240	COG0668	transmembrane transport
H7F24_12245	COG0450	alkyl hydroperoxide reductase
H7F24_12250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_12265	COG0746	molybdenum cofactor guanylyltransferase activity
H7F24_12270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F24_12275	COG0303	'Molybdopterin
H7F24_12280	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7F24_12285	COG0314	molybdopterin synthase activity
H7F24_12290	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H7F24_12305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F24_12310	COG1136	(ABC) transporter
H7F24_12315	COG0577	efflux transmembrane transporter activity
H7F24_12320	COG1349	DNA-binding transcription factor activity
H7F24_12325	COG1105	Belongs to the carbohydrate kinase PfkB family
H7F24_12330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_12330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_12330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_12335	COG0681	Belongs to the peptidase S26 family
H7F24_12345	COG0488	(ABC) transporter
H7F24_12350	COG2309	aminopeptidase activity
H7F24_12360	COG1077	Cell shape determining protein MreB Mrl
H7F24_12365	COG2002	toxin-antitoxin pair type II binding
H7F24_12370	COG3852	Histidine kinase
H7F24_12375	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H7F24_12375	COG2105	PFAM AIG2 family protein
H7F24_12380	COG0569	domain protein
H7F24_12385	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F24_12390	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F24_12395	COG5503	Protein of unknown function (DUF1447)
H7F24_12400	COG0561	phosphatase activity
H7F24_12405	COG0242	peptide deformylase activity
H7F24_12420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F24_12425	COG0022	dehydrogenase e1 component
H7F24_12430	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F24_12435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F24_12440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_12450	COG1982	Orn Lys Arg decarboxylase major
H7F24_12455	COG4476	Belongs to the UPF0223 family
H7F24_12460	COG4493	Belongs to the UPF0637 family
H7F24_12470	COG0483	inositol monophosphate 1-phosphatase activity
H7F24_12485	COG1595	DNA-templated transcription, initiation
H7F24_12505	COG1217	gtp-binding protein TYPA
H7F24_12515	COG4896	Protein conserved in bacteria
H7F24_12525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7F24_12530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F24_12535	COG2066	Belongs to the glutaminase family
H7F24_12540	COG4838	Belongs to the UPF0358 family
H7F24_12545	COG0772	Belongs to the SEDS family
H7F24_12550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H7F24_12555	COG0415	Belongs to the DNA photolyase family
H7F24_12560	COG1612	heme a metabolic process
H7F24_12565	COG0109	protoheme IX farnesyltransferase activity
H7F24_12570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F24_12570	COG2010	Cytochrome c
H7F24_12575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F24_12580	COG1845	cytochrome c oxidase, subunit III
H7F24_12585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F24_12590	COG3336	cytochrome c oxidase
H7F24_12600	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H7F24_12605	COG2340	Cysteine-rich secretory protein family
H7F24_12625	COG3679	Belongs to the UPF0342 family
H7F24_12630	COG4471	UPF0298 protein
H7F24_12635	COG0742	ribosomal rna small subunit methyltransferase
H7F24_12640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7F24_12645	COG3314	Sporulation integral membrane protein YlbJ
H7F24_12650	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F24_12655	COG3480	Lon protease (S16) C-terminal proteolytic domain
H7F24_12665	COG1399	metal-binding, possibly nucleic acid-binding protein
H7F24_12670	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H7F24_12680	COG0454	-acetyltransferase
H7F24_12685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F24_12690	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H7F24_12695	COG2001	Belongs to the MraZ family
H7F24_12700	COG0275	rRNA processing
H7F24_12705	COG4839	cell division protein FtsL
H7F24_12710	COG0768	penicillin binding
H7F24_12715	COG0768	penicillin binding
H7F24_12720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F24_12725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F24_12730	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F24_12735	COG0772	Belongs to the SEDS family
H7F24_12740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F24_12745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7F24_12750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7F24_12755	COG3879	Bacterial protein of unknown function (DUF881)
H7F24_12760	COG3879	Bacterial protein of unknown function (DUF881)
H7F24_12765	COG3856	small basic protein
H7F24_12770	COG0849	cell division
H7F24_12775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7F24_12780	COG1404	Belongs to the peptidase S8 family
H7F24_12780	COG4412	M6 family metalloprotease domain protein
H7F24_12790	COG1191	sigma factor activity
H7F24_12795	COG1191	sigma factor activity
H7F24_12800	COG2390	Transcriptional regulator
H7F24_12815	COG3730	PTS system glucitol sorbitol-specific
H7F24_12820	COG3732	PTS system glucitol sorbitol-specific
H7F24_12830	COG1119	ATPase activity
H7F24_12835	COG1873	PFAM PRC-barrel domain
H7F24_12840	COG1496	oxidoreductase activity
H7F24_12845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7F24_12850	COG1799	cell septum assembly
H7F24_12855	COG0762	integral membrane protein
H7F24_12860	COG2302	S4 RNA-binding domain
H7F24_12865	COG3599	regulation of cell shape
H7F24_12870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7F24_12875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F24_12880	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7F24_12885	COG0564	pseudouridine synthase activity
H7F24_12890	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7F24_12895	COG2233	PERMEase
H7F24_12900	COG0540	Belongs to the ATCase OTCase family
H7F24_12910	COG0505	Belongs to the CarA family
H7F24_12915	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F24_12920	COG0543	2 iron, 2 sulfur cluster binding
H7F24_12925	COG0167	dihydroorotate dehydrogenase activity
H7F24_12930	COG0284	orotidine-5'-phosphate decarboxylase activity
H7F24_12935	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7F24_12945	COG0175	sulfate reduction
H7F24_12950	COG0306	phosphate transporter
H7F24_12955	COG2046	Belongs to the sulfate adenylyltransferase family
H7F24_12960	COG0529	Catalyzes the synthesis of activated sulfate
H7F24_12965	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F24_12970	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H7F24_12975	COG1648	precorrin-2 dehydrogenase activity
H7F24_12985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F24_12990	COG1561	YicC-like family, N-terminal region
H7F24_12995	COG2052	Domain of unknown function (DUF370)
H7F24_13000	COG0194	GDP metabolic process
H7F24_13005	COG1758	RNA polymerase activity
H7F24_13010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F24_13015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F24_13020	COG0242	peptide deformylase activity
H7F24_13025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F24_13030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F24_13030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7F24_13035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F24_13040	COG0631	protein serine/threonine phosphatase activity
H7F24_13045	COG2815	serine threonine protein kinase
H7F24_13045	COG0515	serine threonine protein kinase
H7F24_13050	COG1162	GTPase activity
H7F24_13055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F24_13060	COG1564	THIamine pyrophosphokinase
H7F24_13070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7F24_13075	COG1302	Protein conserved in bacteria
H7F24_13080	COG1461	Dihydroxyacetone kinase
H7F24_13085	COG1760	l-serine dehydratase
H7F24_13090	COG1760	l-serine dehydratase
H7F24_13095	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7F24_13100	COG1349	DNA-binding transcription factor activity
H7F24_13105	COG0416	fatty acid biosynthetic process
H7F24_13110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F24_13115	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_13120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F24_13130	COG1196	nuclear chromosome segregation
H7F24_13135	COG0552	protein localization to endoplasmic reticulum
H7F24_13140	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H7F24_13145	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7F24_13150	COG0228	four-way junction DNA binding
H7F24_13155	COG1837	Belongs to the UPF0109 family
H7F24_13165	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7F24_13170	COG0336	Belongs to the RNA methyltransferase TrmD family
H7F24_13175	COG0335	large ribosomal subunit rRNA binding
H7F24_13180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F24_13185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F24_13195	COG2257	FlhB HrpN YscU SpaS Family
H7F24_13200	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F24_13205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F24_13210	COG0758	DNA mediated transformation
H7F24_13215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F24_13220	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H7F24_13225	COG4974	Belongs to the 'phage' integrase family
H7F24_13230	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F24_13235	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7F24_13240	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F24_13245	COG1815	bacterial-type flagellum-dependent cell motility
H7F24_13250	COG1558	bacterial-type flagellum-dependent cell motility
H7F24_13255	COG1677	Flagellar hook-basal body complex protein FliE
H7F24_13260	COG1766	The M ring may be actively involved in energy transduction
H7F24_13265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F24_13270	COG1317	bacterial-type flagellum organization
H7F24_13275	COG1157	protein secretion by the type III secretion system
H7F24_13280	COG2882	bacterial-type flagellum organization
H7F24_13285	COG3334	PFAM MgtE intracellular
H7F24_13290	COG3144	bacterial-type flagellum assembly
H7F24_13295	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H7F24_13300	COG4786	Flagellar basal body rod
H7F24_13305	COG1582	Flagellar protein (FlbD)
H7F24_13310	COG1580	Controls the rotational direction of flagella during chemotaxis
H7F24_13315	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F24_13320	COG1776	CheC inhibitor of MCP methylation
H7F24_13320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F24_13325	COG2201	protein-glutamate methylesterase activity
H7F24_13330	COG3190	flagellar
H7F24_13335	COG1338	Plays a role in the flagellum-specific transport system
H7F24_13340	COG1987	bacterial-type flagellum assembly
H7F24_13345	COG1684	flagellar biosynthetic protein fliR
H7F24_13350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F24_13355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F24_13360	COG1419	protein localization to endoplasmic reticulum
H7F24_13365	COG0455	bacterial-type flagellum organization
H7F24_13370	COG2201	protein-glutamate methylesterase activity
H7F24_13375	COG0643	Histidine kinase
H7F24_13375	COG2198	Histidine kinase
H7F24_13380	COG0835	chemotaxis
H7F24_13385	COG1776	CheC inhibitor of MCP methylation
H7F24_13395	COG1191	sigma factor activity
H7F24_13410	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7F24_13415	COG0528	UMP kinase activity
H7F24_13420	COG0233	cytoplasmic translational termination
H7F24_13425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7F24_13430	COG4589	Belongs to the CDS family
H7F24_13435	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7F24_13440	COG0750	zinc metalloprotease
H7F24_13445	COG0442	prolyl-tRNA aminoacylation
H7F24_13450	COG2176	DNA-directed DNA polymerase activity
H7F24_13465	COG3693	PFAM glycoside hydrolase, family 10
H7F24_13475	COG0779	Required for maturation of 30S ribosomal subunits
H7F24_13480	COG0195	Participates in both transcription termination and antitermination
H7F24_13485	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H7F24_13490	COG1358	cellular component organization or biogenesis
H7F24_13495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7F24_13500	COG1550	Protein conserved in bacteria
H7F24_13505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7F24_13510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7F24_13515	COG0196	riboflavin kinase activity
H7F24_13520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H7F24_13525	COG1185	polyribonucleotide nucleotidyltransferase activity
H7F24_13530	COG0726	polysaccharide deacetylase
H7F24_13535	COG0612	Peptidase, M16
H7F24_13545	COG1873	PFAM PRC-barrel domain
H7F24_13550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F24_13555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F24_13560	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7F24_13565	COG0527	aspartate kinase activity
H7F24_13575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F24_13580	COG0740	serine-type endopeptidase activity
H7F24_13590	COG1674	ftsk spoiiie
H7F24_13590	COG4980	gas vesicle protein
H7F24_13595	COG2188	Transcriptional regulator
H7F24_13600	COG2814	Major facilitator Superfamily
H7F24_13605	COG2409	Drug exporters of the RND superfamily
H7F24_13605	COG1033	growth of symbiont in host cell
H7F24_13610	COG0612	Peptidase, M16
H7F24_13615	COG0612	Peptidase, M16
H7F24_13625	COG1033	growth of symbiont in host cell
H7F24_13625	COG2409	Drug exporters of the RND superfamily
H7F24_13630	COG0300	oxidoreductase activity
H7F24_13645	COG1426	Protein conserved in bacteria
H7F24_13650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7F24_13655	COG1546	Belongs to the CinA family
H7F24_13655	COG1058	Belongs to the CinA family
H7F24_13660	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H7F24_13665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F24_13670	COG1418	mRNA catabolic process
H7F24_13675	COG1692	metallophosphoesterase
H7F24_13680	COG2359	stage V sporulation protein S
H7F24_13685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F24_13690	COG1063	alcohol dehydrogenase
H7F24_13695	COG0156	8-amino-7-oxononanoate synthase activity
H7F24_13705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F24_13710	COG4550	Control of competence regulator ComK, YlbF/YmcA
H7F24_13720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7F24_13725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7F24_13745	COG1329	Transcriptional regulator
H7F24_13750	COG4195	phage-related replication protein
H7F24_13755	COG0457	Tetratricopeptide repeat
H7F24_13760	COG1404	Belongs to the peptidase S8 family
H7F24_13765	COG4195	phage-related replication protein
H7F24_13770	COG1764	response to oxidative stress
H7F24_13775	COG2076	Multidrug Resistance protein
H7F24_13800	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7F24_13805	COG1923	regulation of RNA biosynthetic process
H7F24_13820	COG1780	Probably involved in ribonucleotide reductase function
H7F24_13825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F24_13830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F24_13835	COG4112	unkown
H7F24_13840	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F24_13845	COG0464	growth
H7F24_13850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7F24_13855	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H7F24_13860	COG0789	Transcriptional regulator
H7F24_13865	COG0174	glutamine synthetase
H7F24_13875	COG4282	regulation of fungal-type cell wall biogenesis
H7F24_13900	COG0457	Tetratricopeptide repeat
H7F24_13905	COG5444	nuclease activity
H7F24_13925	COG5646	InterPro IPR014922
H7F24_13930	COG0457	Tetratricopeptide repeat
H7F24_13935	COG3619	membrane
H7F24_13940	COG3285	dna ligase
H7F24_13940	COG1793	dna ligase
H7F24_13945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H7F24_13950	COG4876	unkown
H7F24_13955	COG0346	lactoylglutathione lyase activity
H7F24_13960	COG1959	2 iron, 2 sulfur cluster binding
H7F24_13965	COG0702	epimerase
H7F24_13985	COG2323	membrane
H7F24_13990	COG1309	transcriptional regulator
H7F24_13995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F24_13995	COG2124	cytochrome p450
H7F24_14000	COG3591	Belongs to the peptidase S1B family
H7F24_14005	COG3209	COG3209 Rhs family protein
H7F24_14010	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_14025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F24_14030	COG1388	LysM domain
H7F24_14035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7F24_14040	COG4224	UPF0291 protein
H7F24_14045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7F24_14055	COG3763	UPF0154 protein
H7F24_14065	COG0785	Cytochrome C biogenesis protein
H7F24_14070	COG4846	Membrane protein involved in cytochrome C biogenesis
H7F24_14080	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F24_14095	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7F24_14100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_14120	COG0824	Thioesterase
H7F24_14130	COG4841	protein insertion into membrane
H7F24_14135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7F24_14140	COG1832	CoA-binding protein
H7F24_14145	COG0187	DNA topoisomerase II activity
H7F24_14150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F24_14160	COG0738	Major facilitator superfamily
H7F24_14165	COG0110	maltose O-acetyltransferase activity
H7F24_14170	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F24_14175	COG1733	regulation of RNA biosynthetic process
H7F24_14185	COG1139	Iron-sulfur cluster binding protein
H7F24_14190	COG0247	lactate metabolic process
H7F24_14205	COG2205	protein histidine kinase activity
H7F24_14205	COG0745	RESPONSE REGULATOR receiver
H7F24_14205	COG3292	Two component regulator propeller
H7F24_14210	COG2197	response regulator
H7F24_14215	COG4585	Histidine kinase
H7F24_14220	COG2409	Drug exporters of the RND superfamily
H7F24_14225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F24_14230	COG0251	oxidation-reduction process
H7F24_14270	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F24_14285	COG0583	DNA-binding transcription factor activity
H7F24_14305	COG0657	acetylesterase activity
H7F24_14310	COG0789	Transcriptional regulator
H7F24_14315	COG2723	6-phospho-beta-galactosidase activity
H7F24_14320	COG1263	PTS System
H7F24_14320	COG2190	(PTS) system
H7F24_14320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F24_14335	COG2205	protein histidine kinase activity
H7F24_14340	COG0745	RESPONSE REGULATOR receiver
H7F24_14350	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F24_14355	COG1012	belongs to the aldehyde dehydrogenase family
H7F24_14360	COG1486	melibiose metabolic process
H7F24_14365	COG0395	ABC-type sugar transport system, permease component
H7F24_14370	COG1175	transmembrane transport
H7F24_14375	COG1653	transport
H7F24_14380	COG1609	Transcriptional regulator
H7F24_14385	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F24_14400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_14430	COG5444	nuclease activity
H7F24_14435	COG1846	Transcriptional regulator
H7F24_14440	COG2814	Major facilitator Superfamily
H7F24_14450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_14450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_14450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_14455	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F24_14455	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_14455	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F24_14460	COG1105	Belongs to the carbohydrate kinase PfkB family
H7F24_14470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F24_14500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F24_14505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F24_14510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F24_14515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F24_14520	COG1024	Enoyl-CoA hydratase
H7F24_14525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F24_14530	COG0511	ligase activity, forming carbon-carbon bonds
H7F24_14535	COG0439	Biotin carboxylase
H7F24_14540	COG0318	PFAM AMP-dependent synthetase and ligase
H7F24_14545	COG1960	acyl-CoA dehydrogenase activity
H7F24_14550	COG1649	PFAM Uncharacterised BCR, COG1649
H7F24_14555	COG2365	Tyrosine phosphatase family
H7F24_14560	COG1349	DNA-binding transcription factor activity
H7F24_14570	COG3835	regulator
H7F24_14575	COG0277	FAD linked oxidase domain protein
H7F24_14580	COG0247	lactate metabolic process
H7F24_14605	COG0166	Belongs to the GPI family
H7F24_14610	COG2246	polysaccharide biosynthetic process
H7F24_14615	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F24_14620	COG0586	Pfam SNARE associated Golgi protein
H7F24_14625	COG1587	Uroporphyrinogen-III synthase
H7F24_14635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F24_14650	COG0534	Mate efflux family protein
H7F24_14655	COG2027	D-alanyl-D-alanine carboxypeptidase
H7F24_14660	COG4677	pectinesterase activity
H7F24_14665	COG2323	membrane
H7F24_14670	COG2146	nitrite reductase [NAD(P)H] activity
H7F24_14675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F24_14680	COG0243	molybdopterin cofactor binding
H7F24_14685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F24_14690	COG2223	nitrite transmembrane transporter activity
H7F24_14695	COG0493	'glutamate synthase
H7F24_14700	COG0067	glutamate synthase
H7F24_14700	COG0070	glutamate synthase
H7F24_14700	COG0069	glutamate synthase activity
H7F24_14705	COG0583	DNA-binding transcription factor activity
H7F24_14715	COG1132	(ABC) transporter
H7F24_14720	COG4978	Transcriptional regulator
H7F24_14720	COG0789	Transcriptional regulator
H7F24_14725	COG0454	-acetyltransferase
H7F24_14730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F24_14735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F24_14750	COG0243	molybdopterin cofactor binding
H7F24_14760	COG1070	Carbohydrate kinase
H7F24_14765	COG2115	Belongs to the xylose isomerase family
H7F24_14780	COG2211	Major facilitator Superfamily
H7F24_14785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F24_14790	COG1994	Peptidase M50
H7F24_14810	COG1309	transcriptional regulator
H7F24_14815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F24_14820	COG3708	Transcriptional regulator
H7F24_14825	COG2378	regulation of single-species biofilm formation
H7F24_14835	COG0640	Transcriptional regulator
H7F24_14840	COG0531	amino acid
H7F24_14845	COG0741	lytic transglycosylase activity
H7F24_14850	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7F24_14855	COG2079	MmgE PrpD family protein
H7F24_14860	COG0372	Belongs to the citrate synthase family
H7F24_14865	COG2322	membrane
H7F24_14875	COG3584	3D domain protein
H7F24_14875	COG1388	LysM domain
H7F24_14880	COG0514	ATP-dependent DNA helicase (RecQ)
H7F24_14890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F24_14915	COG1012	belongs to the aldehyde dehydrogenase family
H7F24_14920	COG1657	PFAM Prenyltransferase squalene oxidase
H7F24_14925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F24_14930	COG0385	Bile acid
H7F24_14935	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F24_14940	COG0567	Dehydrogenase, E1 component
H7F24_14945	COG4548	von Willebrand factor, type A
H7F24_14950	COG0714	Associated with various cellular activities
H7F24_14955	COG2032	superoxide dismutase activity
H7F24_14960	COG1388	LysM domain
H7F24_14960	COG0791	NLP P60 protein
H7F24_14965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F24_14970	COG0534	Mate efflux family protein
H7F24_14975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F24_14980	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F24_14990	COG2962	Rard protein
H7F24_15005	COG1733	regulation of RNA biosynthetic process
H7F24_15010	COG0778	Nitroreductase
H7F24_15020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F24_15025	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H7F24_15030	COG3409	Peptidoglycan-binding domain 1 protein
H7F24_15030	COG0793	Belongs to the peptidase S41A family
H7F24_15035	COG2226	methyltransferase
H7F24_15045	COG1876	peptidase activity
H7F24_15050	COG0813	purine-nucleoside phosphorylase activity
H7F24_15060	COG0671	phosphoesterase, PA-phosphatase related
H7F24_15075	COG4479	Belongs to the UPF0346 family
H7F24_15085	COG1509	lysine 2,3-aminomutase activity
H7F24_15090	COG3829	transcription factor binding
H7F24_15095	COG0463	Glycosyl transferase, family 2
H7F24_15110	COG4641	Protein conserved in bacteria
H7F24_15120	COG1086	Polysaccharide biosynthesis protein
H7F24_15125	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F24_15130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F24_15135	COG1846	Transcriptional regulator
H7F24_15155	COG4698	Protein conserved in bacteria
H7F24_15160	COG2755	lipolytic protein G-D-S-L family
H7F24_15165	COG1999	signal sequence binding
H7F24_15180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F24_15185	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F24_15190	COG1272	protein, Hemolysin III
H7F24_15195	COG0204	Acyl-transferase
H7F24_15200	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F24_15205	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H7F24_15210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F24_15220	COG2136	Putative SAM-dependent methyltransferase
H7F24_15220	COG2521	methyltransferase
H7F24_15230	COG0129	dihydroxy-acid dehydratase activity
H7F24_15235	COG1413	lyase activity
H7F24_15240	COG1418	mRNA catabolic process
H7F24_15245	COG0386	Belongs to the glutathione peroxidase family
H7F24_15250	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H7F24_15255	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H7F24_15260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F24_15270	COG1278	Cold shock
H7F24_15285	COG0328	RNA-DNA hybrid ribonuclease activity
H7F24_15290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H7F24_15295	COG0328	RNA-DNA hybrid ribonuclease activity
H7F24_15305	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F24_15315	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F24_15325	COG1755	Isoprenylcysteine carboxyl methyltransferase
H7F24_15330	COG3424	synthase
H7F24_15340	COG0726	polysaccharide deacetylase
H7F24_15345	COG2233	PERMEase
H7F24_15350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F24_15355	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H7F24_15360	COG1199	ATP-dependent helicase activity
H7F24_15370	COG0116	Belongs to the methyltransferase superfamily
H7F24_15380	COG3599	regulation of cell shape
H7F24_15385	COG4474	Belongs to the UPF0398 family
H7F24_15395	COG3359	exonuclease
H7F24_15400	COG1111	helicase
H7F24_15400	COG1205	dead DEAH box helicase
H7F24_15405	COG1902	pentaerythritol trinitrate reductase activity
H7F24_15410	COG2190	(PTS) system
H7F24_15415	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F24_15445	COG3331	DNA recombination
H7F24_15450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F24_15450	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F24_15460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7F24_15465	COG3935	DnaD domain protein
H7F24_15470	COG0017	Asparaginyl-tRNA synthetase
H7F24_15475	COG5353	protein conserved in bacteria
H7F24_15485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7F24_15485	COG1199	ATP-dependent helicase activity
H7F24_15490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H7F24_15495	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H7F24_15500	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H7F24_15510	COG0617	tRNA 3'-terminal CCA addition
H7F24_15515	COG0438	transferase activity, transferring glycosyl groups
H7F24_15520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F24_15525	COG1803	Methylglyoxal synthase
H7F24_15530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7F24_15535	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F24_15540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F24_15550	COG4347	Protein of unknown function (DUF1405)
H7F24_15555	COG2010	Cytochrome c
H7F24_15555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F24_15560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F24_15565	COG0723	plastoquinol--plastocyanin reductase activity
H7F24_15575	COG5582	Belongs to the UPF0302 family
H7F24_15580	COG0457	Tetratricopeptide repeat
H7F24_15585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7F24_15590	COG0287	Prephenate dehydrogenase
H7F24_15595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F24_15600	COG0159	tryptophan synthase activity
H7F24_15605	COG0133	tryptophan synthase activity
H7F24_15615	COG0134	indole-3-glycerol-phosphate synthase activity
H7F24_15630	COG4401	Chorismate mutase type I
H7F24_15635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7F24_15640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7F24_15645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F24_15650	COG0105	UTP biosynthetic process
H7F24_15655	COG0142	geranyltranstransferase activity
H7F24_15660	COG2226	methyltransferase
H7F24_15665	COG0142	geranyltranstransferase activity
H7F24_15675	COG0302	gtp cyclohydrolase
H7F24_15680	COG0776	regulation of translation
H7F24_15685	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F24_15700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7F24_15705	COG1160	GTP binding
H7F24_15730	COG1304	FMN binding
H7F24_15735	COG0539	negative regulation of cytoplasmic translation
H7F24_15740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H7F24_15750	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H7F24_15755	COG2959	enzyme of heme biosynthesis
H7F24_15760	COG3409	Peptidoglycan-binding domain 1 protein
H7F24_15760	COG3773	Cell wall hydrolase
H7F24_15765	COG2339	peptidase activity
H7F24_15770	COG0492	ferredoxin-NADP+ reductase activity
H7F24_15775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F24_15780	COG4862	establishment of competence for transformation
H7F24_15785	COG1408	metallophosphoesterase
H7F24_15795	COG1388	LysM domain
H7F24_15800	COG1266	CAAX protease self-immunity
H7F24_15805	COG0514	ATP-dependent DNA helicase (RecQ)
H7F24_15810	COG4955	Helix-turn-helix domain
H7F24_15815	COG1141	Ferredoxin
H7F24_15820	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H7F24_15825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F24_15830	COG3409	Peptidoglycan-binding domain 1 protein
H7F24_15830	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F24_15840	COG1595	DNA-templated transcription, initiation
H7F24_15845	COG5002	protein histidine kinase activity
H7F24_15850	COG0745	RESPONSE REGULATOR receiver
H7F24_15855	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F24_15860	COG1333	cytochrome c biogenesis protein
H7F24_15865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_15870	COG1187	pseudouridine synthase activity
H7F24_15875	COG0700	Nucleoside recognition
H7F24_15880	COG2715	membrane protein required for spore maturation
H7F24_15885	COG1686	Belongs to the peptidase S11 family
H7F24_15895	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7F24_15900	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7F24_15910	COG1547	Domain of unknown function (DUF309)
H7F24_15915	COG0456	acetyltransferase
H7F24_15920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F24_15925	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F24_15925	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F24_15930	COG0307	riboflavin synthase, alpha
H7F24_15950	COG2814	Major facilitator Superfamily
H7F24_15955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7F24_15960	COG4086	secreted protein
H7F24_15965	COG0019	diaminopimelate decarboxylase activity
H7F24_15970	COG0697	spore germination
H7F24_15985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F24_16005	COG1191	sigma factor activity
H7F24_16010	COG2172	sigma factor antagonist activity
H7F24_16020	COG1686	Belongs to the peptidase S11 family
H7F24_16025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H7F24_16030	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7F24_16035	COG4974	Belongs to the 'phage' integrase family
H7F24_16045	COG0735	belongs to the Fur family
H7F24_16050	COG1300	Membrane
H7F24_16055	COG1404	Belongs to the peptidase S8 family
H7F24_16065	COG2153	protein acetylation
H7F24_16070	COG1379	DNA repair
H7F24_16075	COG0494	nUDIX hydrolase
H7F24_16080	COG0667	Aldo Keto reductase
H7F24_16095	COG1073	alpha beta
H7F24_16100	COG0457	Tetratricopeptide repeat
H7F24_16115	COG4918	Iron-sulphur cluster biosynthesis
H7F24_16120	COG0456	acetyltransferase
H7F24_16120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7F24_16125	COG0456	acetyltransferase
H7F24_16135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F24_16145	COG2211	Major facilitator Superfamily
H7F24_16150	COG1072	(Pantothenic acid kinase))
H7F24_16155	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7F24_16160	COG0300	oxidoreductase activity
H7F24_16165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F24_16170	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F24_16180	COG4187	Peptidase family M20/M25/M40
H7F24_16185	COG1902	pentaerythritol trinitrate reductase activity
H7F24_16190	COG0596	Alpha beta hydrolase
H7F24_16195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F24_16205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7F24_16210	COG2188	Transcriptional regulator
H7F24_16215	COG2723	6-phospho-beta-galactosidase activity
H7F24_16220	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F24_16225	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F24_16230	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F24_16235	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_16245	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F24_16250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F24_16265	COG0706	membrane insertase activity
H7F24_16275	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F24_16280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F24_16285	COG0346	lactoylglutathione lyase activity
H7F24_16295	COG1376	ErfK ybiS ycfS ynhG family protein
H7F24_16300	COG4129	membrane
H7F24_16305	COG1126	abc transporter atp-binding protein
H7F24_16310	COG0765	amino acid transport
H7F24_16315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F24_16325	COG1597	lipid kinase activity
H7F24_16335	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F24_16340	COG0022	dehydrogenase e1 component
H7F24_16345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F24_16350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F24_16355	COG3426	butyrate kinase activity
H7F24_16360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F24_16365	COG0280	phosphate acetyltransferase
H7F24_16370	COG3829	transcription factor binding
H7F24_16370	COG3290	protein histidine kinase activity
H7F24_16380	COG0584	glycerophosphoryl diester phosphodiesterase
H7F24_16385	COG0457	Tetratricopeptide repeat
H7F24_16395	COG0745	RESPONSE REGULATOR receiver
H7F24_16400	COG0750	zinc metalloprotease
H7F24_16405	COG0497	DNA recombination
H7F24_16410	COG1438	arginine binding
H7F24_16415	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H7F24_16420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F24_16425	COG0142	geranyltranstransferase activity
H7F24_16430	COG1722	exodeoxyribonuclease VII activity
H7F24_16435	COG1570	exodeoxyribonuclease VII activity
H7F24_16440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7F24_16445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F24_16450	COG1302	Protein conserved in bacteria
H7F24_16455	COG0439	Biotin carboxylase
H7F24_16460	COG0511	ligase activity, forming carbon-carbon bonds
H7F24_16500	COG3854	ATPases associated with a variety of cellular activities
H7F24_16510	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7F24_16515	COG0006	proline dipeptidase activity
H7F24_16520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7F24_16530	COG3872	metal-dependent enzyme
H7F24_16540	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F24_16545	COG1321	iron dependent repressor
H7F24_16550	COG0095	Lipoate-protein ligase
H7F24_16555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F24_16560	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F24_16565	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F24_16570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7F24_16575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F24_16600	COG0681	Belongs to the peptidase S26 family
H7F24_16635	COG4970	Tfp pilus assembly protein FimT
H7F24_16640	COG4537	Required for transformation and DNA binding
H7F24_16645	COG1459	type II secretion system
H7F24_16650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F24_16655	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_16665	COG1393	Belongs to the ArsC family
H7F24_16675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F24_16685	COG0011	TIGRFAM Protein of
H7F24_16690	COG2814	Major facilitator Superfamily
H7F24_16695	COG2866	Carboxypeptidase
H7F24_16700	COG1368	sulfuric ester hydrolase activity
H7F24_16705	COG1940	carbohydrate kinase activity
H7F24_16710	COG4483	Protein conserved in bacteria
H7F24_16715	COG0705	Rhomboid family
H7F24_16715	COG0457	Tetratricopeptide repeat
H7F24_16725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7F24_16730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H7F24_16740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F24_16745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F24_16750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F24_16755	COG0581	inorganic phosphate transmembrane transporter activity
H7F24_16760	COG0573	inorganic phosphate transmembrane transporter activity
H7F24_16765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7F24_16770	COG0768	penicillin binding
H7F24_16775	COG0477	Major facilitator Superfamily
H7F24_16780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F24_16785	COG2839	Protein conserved in bacteria
H7F24_16790	COG5521	maltodextrose utilization protein MalA
H7F24_16795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F24_16800	COG1388	LysM domain
H7F24_16805	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7F24_16810	COG4709	membrane
H7F24_16815	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H7F24_16820	COG1940	carbohydrate kinase activity
H7F24_16825	COG0735	belongs to the Fur family
H7F24_16830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F24_16835	COG1121	(ABC) transporter
H7F24_16840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F24_16855	COG0513	Belongs to the DEAD box helicase family
H7F24_16865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7F24_16870	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7F24_16875	COG2384	SAM-dependent methyltransferase
H7F24_16880	COG2010	Cytochrome c
H7F24_16885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7F24_16890	COG0358	DNA primase activity
H7F24_16895	COG1671	Belongs to the UPF0178 family
H7F24_16900	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7F24_16905	COG0517	IMP dehydrogenase activity
H7F24_16910	COG0751	glycine-tRNA ligase activity
H7F24_16915	COG0752	glycyl-tRNA synthetase alpha subunit
H7F24_16920	COG1381	Involved in DNA repair and RecF pathway recombination
H7F24_16930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7F24_16935	COG0295	cytidine deaminase activity
H7F24_16940	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7F24_16945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7F24_16950	COG1480	7TM receptor with intracellular HD hydrolase
H7F24_16955	COG1702	phosphate starvation-inducible protein PhoH
H7F24_16960	COG0561	phosphatase activity
H7F24_16975	COG4864	UPF0365 protein
H7F24_16980	COG1030	water channel activity
H7F24_16985	COG1610	YqeY-like protein
H7F24_16995	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F24_17000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F24_17005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7F24_17010	COG2264	protein methyltransferase activity
H7F24_17015	COG0484	heat shock protein binding
H7F24_17020	COG0443	Heat shock 70 kDa protein
H7F24_17025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7F24_17030	COG1420	regulation of RNA biosynthetic process
H7F24_17035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F24_17040	COG0481	GTPase activity
H7F24_17050	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F24_17055	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H7F24_17060	COG0268	Binds directly to 16S ribosomal RNA
H7F24_17065	COG1466	dna polymerase III delta subunit
H7F24_17075	COG2333	competence protein COMEC
H7F24_17075	COG0658	competence protein
H7F24_17080	COG2131	deaminase
H7F24_17085	COG1555	photosystem II stabilization
H7F24_17090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F24_17095	COG2226	methyltransferase
H7F24_17100	COG0799	negative regulation of ribosome biogenesis
H7F24_17105	COG1713	HD superfamily hydrolase involved in NAD metabolism
H7F24_17110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7F24_17115	COG1534	Rna-binding protein
H7F24_17120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F24_17125	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F24_17130	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H7F24_17145	COG2755	lipolytic protein G-D-S-L family
H7F24_17155	COG0457	Tetratricopeptide repeat
H7F24_17165	COG2186	Transcriptional regulator
H7F24_17180	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_17185	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F24_17190	COG3959	Transketolase, thiamine diphosphate binding domain
H7F24_17215	COG0726	polysaccharide deacetylase
H7F24_17250	COG1131	(ABC) transporter
H7F24_17270	COG2160	L-arabinose isomerase activity
H7F24_17285	COG1609	Transcriptional regulator
H7F24_17295	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7F24_17300	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H7F24_17305	COG1733	regulation of RNA biosynthetic process
H7F24_17310	COG0657	acetylesterase activity
H7F24_17325	COG1309	transcriptional regulator
H7F24_17330	COG0109	protoheme IX farnesyltransferase activity
H7F24_17335	COG2602	Beta-lactamase
H7F24_17340	COG1960	acyl-CoA dehydrogenase activity
H7F24_17345	COG1126	abc transporter atp-binding protein
H7F24_17355	COG0765	amino acid transport
H7F24_17365	COG3546	catalase activity
H7F24_17370	COG1063	alcohol dehydrogenase
H7F24_17380	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_17390	COG1115	amino acid carrier protein
H7F24_17395	COG0583	DNA-binding transcription factor activity
H7F24_17400	COG0842	Transport permease protein
H7F24_17405	COG1511	domain protein
H7F24_17405	COG0842	Transport permease protein
H7F24_17410	COG1131	(ABC) transporter
H7F24_17415	COG2226	methyltransferase
H7F24_17420	COG1063	alcohol dehydrogenase
H7F24_17425	COG2226	methyltransferase
H7F24_17450	COG0626	cystathionine gamma-synthase activity
H7F24_17455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F24_17460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F24_17465	COG2226	methyltransferase
H7F24_17480	COG0768	penicillin binding
H7F24_17485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F24_17495	COG0572	uridine kinase
H7F24_17500	COG0826	peptidase U32
H7F24_17505	COG0826	peptidase U32
H7F24_17510	COG4122	O-methyltransferase activity
H7F24_17515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F24_17520	COG0183	Belongs to the thiolase family
H7F24_17525	COG0318	PFAM AMP-dependent synthetase and ligase
H7F24_17530	COG1268	BioY protein
H7F24_17535	COG3906	Belongs to the UPF0473 family
H7F24_17540	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7F24_17545	COG4472	Bacterial protein of unknown function (DUF965)
H7F24_17550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F24_17555	COG0628	permease
H7F24_17560	COG1126	abc transporter atp-binding protein
H7F24_17565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F24_17570	COG0765	amino acid transport
H7F24_17575	COG0765	amino acid transport
H7F24_17590	COG3881	PFAM PRC-barrel domain
H7F24_17595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7F24_17600	COG0457	Tetratricopeptide repeat
H7F24_17605	COG0482	sulfurtransferase activity
H7F24_17610	COG1104	cysteine desulfurase activity
H7F24_17615	COG1959	2 iron, 2 sulfur cluster binding
H7F24_17620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7F24_17625	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7F24_17640	COG0124	histidyl-tRNA synthetase
H7F24_17650	COG3103	Sh3 type 3 domain protein
H7F24_17650	COG4991	sh3 domain protein
H7F24_17650	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F24_17655	COG1490	D-aminoacyl-tRNA deacylase activity
H7F24_17660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F24_17665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F24_17670	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H7F24_17670	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7F24_17675	COG5416	Lipopolysaccharide assembly protein A domain
H7F24_17680	COG0490	domain, Protein
H7F24_17685	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F24_17685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F24_17695	COG2244	polysaccharide biosynthetic process
H7F24_17700	COG2323	membrane
H7F24_17710	COG1862	Preprotein translocase
H7F24_17715	COG0343	queuine tRNA-ribosyltransferase activity
H7F24_17720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7F24_17730	COG2255	four-way junction helicase activity
H7F24_17735	COG0632	four-way junction helicase activity
H7F24_17745	COG2112	serine threonine protein kinase
H7F24_17760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7F24_17775	COG1388	LysM domain
H7F24_17775	COG1388	LysM domain
H7F24_17780	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7F24_17785	COG0157	Belongs to the NadC ModD family
H7F24_17790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7F24_17795	COG1104	cysteine desulfurase activity
H7F24_17800	COG1827	regulation of RNA biosynthetic process
H7F24_17805	COG0077	Prephenate dehydratase
H7F24_17810	COG4492	Belongs to the UPF0735 family
H7F24_17815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7F24_17820	COG3290	protein histidine kinase activity
H7F24_17825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7F24_17830	COG2868	ribosomal protein
H7F24_17835	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7F24_17840	COG1994	Peptidase M50
H7F24_17845	COG0739	heme binding
H7F24_17850	COG2894	cell division
H7F24_17855	COG0850	regulation of cytokinetic process
H7F24_17860	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7F24_17870	COG1077	Cell shape determining protein MreB Mrl
H7F24_17875	COG2003	Belongs to the UPF0758 family
H7F24_17880	COG0424	maF-like protein
H7F24_17890	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7F24_17895	COG0285	dihydrofolate synthase activity
H7F24_17900	COG0525	valine-tRNA ligase activity
H7F24_17905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F24_17910	COG1388	LysM domain
H7F24_17915	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F24_17920	COG0113	porphobilinogen synthase activity
H7F24_17925	COG1587	Uroporphyrinogen-III synthase
H7F24_17930	COG0181	hydroxymethylbilane synthase activity
H7F24_17935	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F24_17940	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7F24_17950	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7F24_17955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7F24_17960	COG0470	DNA polymerase III
H7F24_17960	COG1067	ATP-dependent peptidase activity
H7F24_17965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7F24_17970	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7F24_17975	COG1477	protein flavinylation
H7F24_17975	COG0457	Tetratricopeptide repeat
H7F24_17980	COG0066	3-isopropylmalate dehydratase activity
H7F24_17985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F24_17990	COG0473	3-isopropylmalate dehydrogenase activity
H7F24_17995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F24_18000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7F24_18005	COG0440	acetolactate synthase activity
H7F24_18010	COG0028	Belongs to the TPP enzyme family
H7F24_18015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F24_18020	COG2706	6-phosphogluconolactonase activity
H7F24_18025	COG3339	Conserved Protein
H7F24_18030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H7F24_18035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F24_18040	COG1696	Membrane protein involved in D-alanine export
H7F24_18090	COG0622	Phosphoesterase
H7F24_18095	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7F24_18100	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7F24_18105	COG5401	PFAM Sporulation and spore germination
H7F24_18110	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7F24_18115	COG1846	Transcriptional regulator
H7F24_18120	COG2197	response regulator
H7F24_18125	COG2851	Citrate transporter
H7F24_18130	COG0583	DNA-binding transcription factor activity
H7F24_18135	COG2828	Protein conserved in bacteria
H7F24_18145	COG0824	Thioesterase
H7F24_18150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7F24_18155	COG1053	succinate dehydrogenase
H7F24_18160	COG2009	succinate dehydrogenase
H7F24_18165	COG1719	4-vinyl reductase, 4VR
H7F24_18170	COG0527	aspartate kinase activity
H7F24_18175	COG0322	excinuclease ABC activity
H7F24_18180	COG3118	belongs to the thioredoxin family
H7F24_18185	COG3534	alpha-L-arabinofuranosidase
H7F24_18190	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H7F24_18195	COG2086	electron transfer activity
H7F24_18200	COG1024	Enoyl-CoA hydratase
H7F24_18205	COG1309	transcriptional regulator
H7F24_18210	COG0318	PFAM AMP-dependent synthetase and ligase
H7F24_18220	COG3766	membrane
H7F24_18225	COG1193	negative regulation of DNA recombination
H7F24_18230	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F24_18230	COG1796	DNA polymerase
H7F24_18235	COG1286	toxin biosynthetic process
H7F24_18240	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H7F24_18245	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F24_18255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F24_18255	COG0072	phenylalanine-tRNA ligase activity
H7F24_18260	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7F24_18265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F24_18275	COG1966	Carbon starvation protein
H7F24_18280	COG1363	Peptidase, m42
H7F24_18290	COG3326	Membrane
H7F24_18295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7F24_18300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7F24_18305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7F24_18310	COG1346	cytolysis
H7F24_18320	COG3279	Response regulator of the LytR AlgR family
H7F24_18325	COG3275	phosphorelay sensor kinase activity
H7F24_18330	COG1011	Hydrolase
H7F24_18340	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F24_18350	COG0398	Pfam SNARE associated Golgi protein
H7F24_18355	COG1484	DNA-dependent DNA replication
H7F24_18360	COG3611	Membrane attachment protein
H7F24_18365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7F24_18375	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H7F24_18380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F24_18385	COG0237	dephospho-CoA kinase activity
H7F24_18390	COG1971	Probably functions as a manganese efflux pump
H7F24_18395	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7F24_18400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F24_18400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F24_18405	COG5002	protein histidine kinase activity
H7F24_18410	COG0745	RESPONSE REGULATOR receiver
H7F24_18415	COG0039	L-malate dehydrogenase activity
H7F24_18420	COG0538	isocitrate dehydrogenase activity
H7F24_18425	COG0372	Belongs to the citrate synthase family
H7F24_18430	COG2707	UPF0756 membrane protein
H7F24_18435	COG0628	permease
H7F24_18440	COG3030	protein affecting phage T7 exclusion by the F plasmid
H7F24_18450	COG0205	6-phosphofructokinase activity
H7F24_18455	COG0825	malonyl-CoA metabolic process
H7F24_18460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7F24_18465	COG0281	malic enzyme
H7F24_18470	COG0587	DNA-directed DNA polymerase activity
H7F24_18490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7F24_18500	COG4109	DRTGG domain
H7F24_18505	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F24_18510	COG1028	Short-chain dehydrogenase reductase Sdr
H7F24_18520	COG0165	Argininosuccinate lyase
H7F24_18525	COG0137	argininosuccinate synthase activity
H7F24_18530	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7F24_18535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7F24_18540	COG0827	DNA restriction-modification system
H7F24_18545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H7F24_18550	COG3874	Sporulation protein YtfJ
H7F24_18560	COG1714	RDD family
H7F24_18565	COG0616	signal peptide processing
H7F24_18570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F24_18580	COG3239	Fatty acid desaturase
H7F24_18585	COG4585	Histidine kinase
H7F24_18590	COG2197	response regulator
H7F24_18595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F24_18600	COG0745	RESPONSE REGULATOR receiver
H7F24_18605	COG0642	Histidine kinase
H7F24_18610	COG1136	(ABC) transporter
H7F24_18615	COG0577	efflux transmembrane transporter activity
H7F24_18620	COG0402	S-adenosylhomocysteine deaminase activity
H7F24_18635	COG1279	arginine transmembrane transporter activity
H7F24_18655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F24_18665	COG0301	tRNA thio-modification
H7F24_18670	COG1104	cysteine desulfurase activity
H7F24_18675	COG1114	Component of the transport system for branched-chain amino acids
H7F24_18680	COG1114	Component of the transport system for branched-chain amino acids
H7F24_18685	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H7F24_18690	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F24_18695	COG1309	transcriptional regulator
H7F24_18700	COG1956	GAF domain-containing protein
H7F24_18705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H7F24_18710	COG1335	isochorismatase
H7F24_18720	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F24_18725	COG2329	Antibiotic biosynthesis monooxygenase
H7F24_18730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F24_18735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F24_18740	COG0454	-acetyltransferase
H7F24_18745	COG0517	IMP dehydrogenase activity
H7F24_18750	COG0123	including yeast histone deacetylase and acetoin utilization protein
H7F24_18755	COG1609	Transcriptional regulator
H7F24_18760	COG1605	Chorismate mutase
H7F24_18760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H7F24_18765	COG3118	belongs to the thioredoxin family
H7F24_18770	COG4980	gas vesicle protein
H7F24_18775	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H7F24_18780	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F24_18785	COG1674	ftsk spoiiie
H7F24_18790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F24_18795	COG4848	Belongs to the UPF0354 family
H7F24_18800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F24_18815	COG1363	Peptidase, m42
H7F24_18820	COG5584	Small secreted protein
H7F24_18825	COG0281	malic enzyme
H7F24_18830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F24_18835	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7F24_18845	COG0510	thiamine kinase activity
H7F24_18850	COG1597	lipid kinase activity
H7F24_18860	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F24_18865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F24_18870	COG3340	Belongs to the peptidase S51 family
H7F24_18875	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F24_18880	COG2252	PERMEase
H7F24_18885	COG1349	DNA-binding transcription factor activity
H7F24_18890	COG1187	pseudouridine synthase activity
H7F24_18895	COG2244	polysaccharide biosynthetic process
H7F24_18900	COG2081	HI0933 family
H7F24_18910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7F24_18915	COG3196	Protein conserved in bacteria
H7F24_18925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F24_18930	COG5578	integral membrane protein
H7F24_18935	COG0673	inositol 2-dehydrogenase activity
H7F24_18940	COG1653	transport
H7F24_18945	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F24_18950	COG4209	transmembrane transport
H7F24_18955	COG2207	Transcriptional regulator
H7F24_18960	COG1733	regulation of RNA biosynthetic process
H7F24_18965	COG2814	Major facilitator Superfamily
H7F24_18970	COG0656	L-ascorbic acid biosynthetic process
H7F24_18975	COG1653	transport
H7F24_18980	COG0395	ABC-type sugar transport system, permease component
H7F24_18985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F24_18990	COG1073	alpha beta
H7F24_18995	COG0495	leucyl-tRNA aminoacylation
H7F24_19005	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F24_19005	COG2202	Pas domain
H7F24_19010	COG2433	Pfam Transposase IS66
H7F24_19015	COG0577	efflux transmembrane transporter activity
H7F24_19020	COG1136	(ABC) transporter
H7F24_19030	COG1131	(ABC) transporter
H7F24_19035	COG1725	Transcriptional regulator
H7F24_19050	COG1242	4 iron, 4 sulfur cluster binding
H7F24_19055	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H7F24_19065	COG2267	carboxylic ester hydrolase activity
H7F24_19070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7F24_19075	COG0367	asparagine synthase
H7F24_19080	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7F24_19085	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H7F24_19095	COG1506	peptidase
H7F24_19100	COG1233	COG1233 Phytoene dehydrogenase and related
H7F24_19120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F24_19125	COG1116	anion transmembrane transporter activity
H7F24_19130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F24_19135	COG0494	nUDIX hydrolase
H7F24_19140	COG2310	stress, protein
H7F24_19155	COG4824	toxin secretion phage lysis holin
H7F24_19165	COG0783	Belongs to the Dps family
H7F24_19180	COG1854	S-ribosylhomocysteine lyase activity
H7F24_19185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F24_19190	COG0288	reversible hydration of carbon dioxide
H7F24_19195	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F24_19195	COG3443	Belongs to the bacterial solute-binding protein 9 family
H7F24_19210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F24_19215	COG1854	S-ribosylhomocysteine lyase activity
H7F24_19240	COG4824	toxin secretion phage lysis holin
H7F24_19255	COG2310	stress, protein
H7F24_19260	COG0494	nUDIX hydrolase