locus-tag	class	description
H7F27_00010	COG3870	Protein conserved in bacteria
H7F27_00015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H7F27_00020	COG1982	Orn Lys Arg decarboxylase major
H7F27_00025	COG3853	Toxic anion resistance protein (TelA)
H7F27_00030	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
H7F27_00075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7F27_00080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H7F27_00085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7F27_00095	COG0590	tRNA wobble adenosine to inosine editing
H7F27_00100	COG1335	isochorismatase
H7F27_00105	COG3858	chitin binding
H7F27_00105	COG1388	LysM domain
H7F27_00110	COG1428	Deoxynucleoside kinase
H7F27_00115	COG1428	Deoxynucleoside kinase
H7F27_00125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H7F27_00130	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
H7F27_00140	COG1686	Belongs to the peptidase S11 family
H7F27_00145	COG0516	GMP reductase activity
H7F27_00145	COG0517	IMP dehydrogenase activity
H7F27_00180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F27_00195	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H7F27_00200	COG2501	S4 domain
H7F27_00205	COG0592	DNA-directed DNA polymerase activity
H7F27_00210	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H7F27_00220	COG0594	ribonuclease P activity
H7F27_00225	COG0706	membrane insertase activity
H7F27_00230	COG1847	R3H domain protein
H7F27_00235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H7F27_00240	COG0445	tRNA wobble uridine modification
H7F27_00245	COG0357	Ribosomal RNA small subunit methyltransferase G
H7F27_00250	COG1475	DNA binding
H7F27_00260	COG1192	Involved in chromosome partitioning
H7F27_00265	COG1475	DNA binding
H7F27_00275	COG3949	Membrane
H7F27_00280	COG4481	Protein conserved in bacteria
H7F27_00285	COG0243	molybdopterin cofactor binding
H7F27_00290	COG0012	GTP binding
H7F27_00295	COG0360	Binds together with S18 to 16S ribosomal RNA
H7F27_00300	COG0629	single-stranded DNA binding
H7F27_00310	COG0708	Exodeoxyribonuclease III
H7F27_00315	COG1609	Transcriptional regulator
H7F27_00320	COG0346	lactoylglutathione lyase activity
H7F27_00325	COG0110	maltose O-acetyltransferase activity
H7F27_00330	COG2814	Major facilitator Superfamily
H7F27_00330	COG0477	Major facilitator Superfamily
H7F27_00335	COG1266	CAAX protease self-immunity
H7F27_00340	COG1331	Highly conserved protein containing a thioredoxin domain
H7F27_00350	COG2856	Zn peptidase
H7F27_00355	COG1396	sequence-specific DNA binding
H7F27_00380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F27_00400	COG2207	Transcriptional regulator
H7F27_00400	COG3708	Transcriptional regulator
H7F27_00405	COG1811	Na channel or pump
H7F27_00410	COG0789	Transcriptional regulator
H7F27_00410	COG4978	Transcriptional regulator
H7F27_00415	COG1309	transcriptional regulator
H7F27_00430	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F27_00435	COG0640	Transcriptional regulator
H7F27_00445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_00460	COG0583	DNA-binding transcription factor activity
H7F27_00470	COG2153	protein acetylation
H7F27_00475	COG0583	DNA-binding transcription factor activity
H7F27_00480	COG2814	Major facilitator Superfamily
H7F27_00485	COG1357	PFAM Pentapeptide repeats (8 copies)
H7F27_00490	COG4319	ketosteroid isomerase
H7F27_00500	COG4978	Transcriptional regulator
H7F27_00500	COG0789	Transcriptional regulator
H7F27_00505	COG2271	Major facilitator Superfamily
H7F27_00520	COG1227	inorganic diphosphatase activity
H7F27_00530	COG5577	PFAM Coat F domain
H7F27_00540	COG4241	membrane
H7F27_00545	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
H7F27_00550	COG0359	binds to the 23S rRNA
H7F27_00555	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F27_00560	COG2807	transmembrane transport
H7F27_00565	COG3093	addiction module antidote protein HigA
H7F27_00580	COG0305	Participates in initiation and elongation during chromosome replication
H7F27_00585	COG0346	lactoylglutathione lyase activity
H7F27_00615	COG0745	RESPONSE REGULATOR receiver
H7F27_00620	COG5002	protein histidine kinase activity
H7F27_00625	COG4863	YycH protein
H7F27_00630	COG4853	Protein conserved in bacteria
H7F27_00635	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
H7F27_00640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F27_00645	COG3829	transcription factor binding
H7F27_00650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F27_00655	COG0833	amino acid
H7F27_00660	COG0010	Belongs to the arginase family
H7F27_00670	COG0457	Tetratricopeptide repeat
H7F27_00675	COG0456	acetyltransferase
H7F27_00680	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
H7F27_00700	COG1063	alcohol dehydrogenase
H7F27_00715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H7F27_00735	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
H7F27_00745	COG2188	Transcriptional regulator
H7F27_00750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_00750	COG2190	(PTS) system
H7F27_00750	COG1263	PTS System
H7F27_00755	COG2723	6-phospho-beta-galactosidase activity
H7F27_00765	COG3634	alkyl hydroperoxide reductase activity
H7F27_00770	COG0450	alkyl hydroperoxide reductase
H7F27_00775	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F27_00780	COG2610	gluconate transmembrane transporter activity
H7F27_00785	COG1070	Carbohydrate kinase
H7F27_00790	COG1802	Transcriptional regulator
H7F27_00795	COG1929	Belongs to the glycerate kinase type-1 family
H7F27_00800	COG5039	Polysaccharide pyruvyl transferase
H7F27_00820	COG1346	cytolysis
H7F27_00825	COG1380	Effector of murein hydrolase LrgA
H7F27_00830	COG1846	Transcriptional regulator
H7F27_00835	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_00840	COG1309	transcriptional regulator
H7F27_00845	COG1917	Cupin 2, conserved barrel domain protein
H7F27_00850	COG2311	Membrane
H7F27_00855	COG1714	RDD family
H7F27_00860	COG0789	Transcriptional regulator
H7F27_00870	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_00875	COG1309	transcriptional regulator
H7F27_00910	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_00920	COG0326	Molecular chaperone. Has ATPase activity
H7F27_00925	COG2814	Major facilitator Superfamily
H7F27_00950	COG0667	Aldo Keto reductase
H7F27_00955	COG1349	DNA-binding transcription factor activity
H7F27_00960	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_00970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F27_00975	COG3962	Belongs to the TPP enzyme family
H7F27_00980	COG1082	Xylose isomerase domain protein TIM barrel
H7F27_00985	COG2814	Major facilitator Superfamily
H7F27_00990	COG0673	inositol 2-dehydrogenase activity
H7F27_00995	COG1082	Xylose isomerase domain protein TIM barrel
H7F27_01005	COG0191	fructose-bisphosphate aldolase activity
H7F27_01010	COG0745	RESPONSE REGULATOR receiver
H7F27_01015	COG2205	protein histidine kinase activity
H7F27_01020	COG1136	(ABC) transporter
H7F27_01025	COG0577	efflux transmembrane transporter activity
H7F27_01030	COG5294	Protein conserved in bacteria
H7F27_01035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F27_01065	COG0561	phosphatase activity
H7F27_01070	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
H7F27_01080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F27_01085	COG0456	acetyltransferase
H7F27_01090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F27_01095	COG0765	amino acid transport
H7F27_01100	COG1126	abc transporter atp-binding protein
H7F27_01105	COG1473	amidohydrolase
H7F27_01110	COG2079	MmgE PrpD family protein
H7F27_01115	COG3192	ethanolamine utilization protein
H7F27_01125	COG2390	Transcriptional regulator
H7F27_01130	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H7F27_01135	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F27_01140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H7F27_01145	COG0833	amino acid
H7F27_01150	COG0010	Belongs to the arginase family
H7F27_01155	COG1228	amidohydrolase
H7F27_01160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H7F27_01165	COG2986	histidine ammonia-lyase
H7F27_01180	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F27_01190	COG0494	nUDIX hydrolase
H7F27_01210	COG5444	nuclease activity
H7F27_01230	COG1263	PTS System
H7F27_01230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_01230	COG2190	(PTS) system
H7F27_01235	COG2723	6-phospho-beta-galactosidase activity
H7F27_01240	COG0589	response to stress
H7F27_01245	COG0697	spore germination
H7F27_01275	COG2755	lipolytic protein G-D-S-L family
H7F27_01275	COG3401	FG-GAP repeat protein
H7F27_01280	COG0513	Belongs to the DEAD box helicase family
H7F27_01295	COG3711	transcriptional antiterminator
H7F27_01300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_01300	COG1263	PTS System
H7F27_01300	COG2190	(PTS) system
H7F27_01305	COG2723	6-phospho-beta-galactosidase activity
H7F27_01315	COG2851	Citrate transporter
H7F27_01320	COG0753	catalase activity
H7F27_01320	COG0693	protein deglycase activity
H7F27_01335	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F27_01340	COG0500	methyltransferase
H7F27_01345	COG2610	gluconate transmembrane transporter activity
H7F27_01350	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7F27_01355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F27_01360	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_01365	COG3829	transcription factor binding
H7F27_01365	COG3290	protein histidine kinase activity
H7F27_01370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F27_01375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F27_01380	COG4894	glucomannan catabolic process
H7F27_01390	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F27_01400	COG0583	DNA-binding transcription factor activity
H7F27_01405	COG1881	PFAM PEBP family protein
H7F27_01410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7F27_01420	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F27_01425	COG2508	Transcriptional regulator
H7F27_01430	COG3842	ATPase activity
H7F27_01440	COG0726	polysaccharide deacetylase
H7F27_01450	COG0501	Belongs to the peptidase M48B family
H7F27_01455	COG3493	citrate carrier protein
H7F27_01460	COG1271	oxidase subunit
H7F27_01465	COG1294	oxidase, subunit
H7F27_01470	COG4988	ABC transporter
H7F27_01475	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H7F27_01480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7F27_01485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7F27_01490	COG1595	DNA-templated transcription, initiation
H7F27_01510	COG1131	(ABC) transporter
H7F27_01515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F27_01520	COG2814	Major facilitator Superfamily
H7F27_01525	COG0753	catalase activity
H7F27_01530	COG2094	Belongs to the DNA glycosylase MPG family
H7F27_01540	COG3711	transcriptional antiterminator
H7F27_01540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_01545	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F27_01550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F27_01555	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F27_01560	COG1486	melibiose metabolic process
H7F27_01565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F27_01570	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
H7F27_01575	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
H7F27_01580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F27_01585	COG1696	Membrane protein involved in D-alanine export
H7F27_01590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_01600	COG1575	Belongs to the MenA family. Type 1 subfamily
H7F27_01605	COG2357	RelA SpoT domain protein
H7F27_01610	COG2234	aminopeptidase activity
H7F27_01615	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F27_01620	COG1846	Transcriptional regulator
H7F27_01625	COG5522	Integral membrane protein (intg_mem_TP0381)
H7F27_01630	COG1442	glycosyl transferase family 8
H7F27_01635	COG3711	transcriptional antiterminator
H7F27_01640	COG1263	PTS System
H7F27_01640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_01645	COG1404	Belongs to the peptidase S8 family
H7F27_01650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F27_01660	COG0346	lactoylglutathione lyase activity
H7F27_01665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H7F27_01670	COG4895	conserved protein (DUF2196)
H7F27_01675	COG2814	Major facilitator Superfamily
H7F27_01680	COG1346	cytolysis
H7F27_01685	COG1380	Effector of murein hydrolase LrgA
H7F27_01690	COG0583	DNA-binding transcription factor activity
H7F27_01695	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H7F27_01700	COG0352	thiamine-phosphate diphosphorylase activity
H7F27_01705	COG0672	)-iron permease
H7F27_01710	COG2822	iron ion transport
H7F27_01715	COG2837	iron assimilation
H7F27_01720	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F27_01725	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F27_01730	COG3162	membrane
H7F27_01740	COG1309	transcriptional regulator
H7F27_01745	COG2246	polysaccharide biosynthetic process
H7F27_01750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H7F27_01755	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
H7F27_01760	COG2261	transglycosylase associated protein
H7F27_01765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F27_01770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F27_01790	COG0772	Belongs to the SEDS family
H7F27_01795	COG0778	Nitroreductase
H7F27_01800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F27_01805	COG1404	Belongs to the peptidase S8 family
H7F27_01815	COG3711	transcriptional antiterminator
H7F27_01820	COG2116	formate transmembrane transporter activity
H7F27_01825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_01825	COG1263	PTS System
H7F27_01830	COG1621	beta-fructofuranosidase activity
H7F27_01840	COG0351	phosphomethylpyrimidine kinase
H7F27_01845	COG1695	Transcriptional regulator
H7F27_01860	COG1216	Glycosyl transferase, family 2
H7F27_01865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H7F27_01870	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_01880	COG2233	PERMEase
H7F27_01885	COG2363	Small membrane protein
H7F27_01900	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F27_01905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F27_01910	COG0456	acetyltransferase
H7F27_01915	COG2089	acid synthase
H7F27_01920	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
H7F27_01925	COG3980	spore coat polysaccharide biosynthesis protein
H7F27_01930	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H7F27_01935	COG1088	dTDP-glucose 4,6-dehydratase activity
H7F27_01940	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7F27_01945	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
H7F27_01955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F27_01960	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_01965	COG4187	Peptidase family M20/M25/M40
H7F27_01970	COG0833	amino acid
H7F27_01980	COG2814	Major facilitator Superfamily
H7F27_01985	COG0077	Prephenate dehydratase
H7F27_01990	COG1917	Cupin 2, conserved barrel domain protein
H7F27_01995	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_02000	COG0151	Belongs to the GarS family
H7F27_02005	COG2814	Major facilitator Superfamily
H7F27_02010	COG0436	Aminotransferase
H7F27_02015	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_02020	COG3253	May function as heme-dependent peroxidase
H7F27_02025	COG0280	phosphate acetyltransferase
H7F27_02030	COG0583	DNA-binding transcription factor activity
H7F27_02035	COG0095	Lipoate-protein ligase
H7F27_02040	COG0697	spore germination
H7F27_02050	COG4844	belongs to the
H7F27_02055	COG1078	dGTPase activity
H7F27_02060	COG3465	dGTPase activity
H7F27_02065	COG1959	2 iron, 2 sulfur cluster binding
H7F27_02070	COG0477	Major facilitator Superfamily
H7F27_02075	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F27_02080	COG1846	Transcriptional regulator
H7F27_02085	COG1942	4-Oxalocrotonate Tautomerase
H7F27_02090	COG1994	Peptidase M50
H7F27_02105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F27_02110	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H7F27_02115	COG0010	Belongs to the arginase family
H7F27_02130	COG0457	Tetratricopeptide repeat
H7F27_02135	COG3391	amine dehydrogenase activity
H7F27_02155	COG0612	Peptidase, M16
H7F27_02165	COG1131	(ABC) transporter
H7F27_02175	COG0535	radical SAM domain protein
H7F27_02185	COG4506	Protein conserved in bacteria
H7F27_02195	COG2223	nitrite transmembrane transporter activity
H7F27_02200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F27_02210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7F27_02215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H7F27_02220	COG1140	nitrate reductase beta subunit
H7F27_02225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H7F27_02230	COG2181	nitrate reductase activity
H7F27_02240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F27_02250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F27_02260	COG4294	response to UV
H7F27_02265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F27_02270	COG0247	lactate metabolic process
H7F27_02270	COG2181	nitrate reductase activity
H7F27_02275	COG1960	acyl-CoA dehydrogenase activity
H7F27_02280	COG3343	RNA polymerase activity
H7F27_02285	COG0504	CTP synthase activity
H7F27_02290	COG4821	SIS domain
H7F27_02295	COG2204	response regulator
H7F27_02300	COG0191	fructose-bisphosphate aldolase activity
H7F27_02305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7F27_02310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F27_02315	COG1494	fructose-1,6-bisphosphatase
H7F27_02325	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H7F27_02335	COG1435	thymidine kinase activity
H7F27_02340	COG0281	malic enzyme
H7F27_02345	COG0679	Auxin Efflux Carrier
H7F27_02350	COG0789	Transcriptional regulator
H7F27_02355	COG0346	lactoylglutathione lyase activity
H7F27_02360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H7F27_02365	COG2890	protein-(glutamine-N5) methyltransferase activity
H7F27_02385	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H7F27_02390	COG0009	L-threonylcarbamoyladenylate synthase
H7F27_02395	COG1971	Probably functions as a manganese efflux pump
H7F27_02405	COG0698	ribose 5-phosphate isomerase
H7F27_02410	COG4475	Protein of unknown function (DUF436)
H7F27_02415	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H7F27_02420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H7F27_02430	COG0356	it plays a direct role in the translocation of protons across the membrane
H7F27_02440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H7F27_02445	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H7F27_02455	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H7F27_02460	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H7F27_02465	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H7F27_02475	COG4836	Membrane
H7F27_02485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7F27_02490	COG2385	sporulation resulting in formation of a cellular spore
H7F27_02495	COG2304	oxidoreductase activity
H7F27_02500	COG2304	oxidoreductase activity
H7F27_02510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7F27_02515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7F27_02520	COG0457	Tetratricopeptide repeat
H7F27_02525	COG1994	Peptidase M50
H7F27_02530	COG3237	CsbD-like
H7F27_02560	COG0831	urea catabolic process
H7F27_02565	COG0832	Belongs to the urease beta subunit family
H7F27_02570	COG0804	urea catabolic process
H7F27_02575	COG1959	2 iron, 2 sulfur cluster binding
H7F27_02580	COG2910	NAD(P)H-binding
H7F27_02590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7F27_02605	COG1247	-acetyltransferase
H7F27_02610	COG0739	heme binding
H7F27_02620	COG0671	phosphoesterase, PA-phosphatase related
H7F27_02625	COG0347	Belongs to the P(II) protein family
H7F27_02630	COG0004	ammonium transporteR
H7F27_02640	COG1335	isochorismatase
H7F27_02645	COG0477	Major facilitator Superfamily
H7F27_02650	COG1953	Uracil, thiamine, allantoin
H7F27_02655	COG3420	alginic acid biosynthetic process
H7F27_02660	COG2814	Major facilitator Superfamily
H7F27_02665	COG1846	Transcriptional regulator
H7F27_02675	COG1609	Transcriptional regulator
H7F27_02680	COG1077	Cell shape determining protein MreB Mrl
H7F27_02685	COG4786	Flagellar basal body rod
H7F27_02690	COG4786	Flagellar basal body rod
H7F27_02695	COG0457	Tetratricopeptide repeat
H7F27_02700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F27_02705	COG1970	mechanosensitive ion channel activity
H7F27_02710	COG2972	Histidine kinase
H7F27_02710	COG0745	RESPONSE REGULATOR receiver
H7F27_02715	COG3279	Response regulator of the LytR AlgR family
H7F27_02725	COG3764	Sortase (surface protein transpeptidase)
H7F27_02730	COG2602	Beta-lactamase
H7F27_02745	COG0629	single-stranded DNA binding
H7F27_02750	COG1349	DNA-binding transcription factor activity
H7F27_02755	COG0561	phosphatase activity
H7F27_02760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F27_02765	COG4715	Zinc finger, swim domain protein
H7F27_02775	COG3944	biosynthesis protein
H7F27_02780	COG0489	protein tyrosine kinase activity
H7F27_02785	COG4464	protein tyrosine phosphatase activity
H7F27_02790	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F27_02815	COG5444	nuclease activity
H7F27_02850	COG0583	DNA-binding transcription factor activity
H7F27_02855	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F27_02860	COG2059	Chromate
H7F27_02865	COG2059	Chromate
H7F27_02870	COG1522	sequence-specific DNA binding
H7F27_02875	COG0405	Gamma-glutamyltransferase
H7F27_02885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F27_02900	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_02905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7F27_02915	COG5337	Spore coat protein CotH
H7F27_02930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F27_02935	COG0583	DNA-binding transcription factor activity
H7F27_02940	COG0028	Belongs to the TPP enzyme family
H7F27_02945	COG3527	Alpha-acetolactate decarboxylase
H7F27_02950	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F27_02960	COG3103	Sh3 type 3 domain protein
H7F27_02965	COG1879	ABC-type sugar transport system periplasmic component
H7F27_02970	COG1172	Belongs to the binding-protein-dependent transport system permease family
H7F27_02975	COG1129	ABC transporter
H7F27_02980	COG1869	D-ribose catabolic process
H7F27_02985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F27_02990	COG1609	Transcriptional regulator
H7F27_02995	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F27_03005	COG2843	Capsule synthesis protein
H7F27_03020	COG0791	NLP P60 protein
H7F27_03025	COG0561	phosphatase activity
H7F27_03030	COG1316	TRANSCRIPTIONal
H7F27_03035	COG2814	Major facilitator Superfamily
H7F27_03045	COG0814	amino acid
H7F27_03050	COG0697	spore germination
H7F27_03055	COG1482	cell wall glycoprotein biosynthetic process
H7F27_03060	COG4193	domain, Protein
H7F27_03070	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F27_03075	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
H7F27_03080	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H7F27_03085	COG0438	transferase activity, transferring glycosyl groups
H7F27_03090	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F27_03095	COG1682	transport, permease protein
H7F27_03100	COG1134	teichoic acid transport
H7F27_03115	COG0463	Glycosyl transferase, family 2
H7F27_03120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
H7F27_03120	COG1215	transferase activity, transferring glycosyl groups
H7F27_03140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F27_03145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H7F27_03150	COG1316	TRANSCRIPTIONal
H7F27_03160	COG2385	sporulation resulting in formation of a cellular spore
H7F27_03160	COG2247	cell wall binding repeat
H7F27_03165	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F27_03165	COG2247	cell wall binding repeat
H7F27_03180	COG2244	polysaccharide biosynthetic process
H7F27_03185	COG0438	transferase activity, transferring glycosyl groups
H7F27_03185	COG0297	glycogen (starch) synthase activity
H7F27_03190	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
H7F27_03195	COG3307	-O-antigen
H7F27_03200	COG3206	protein involved in exopolysaccharide biosynthesis
H7F27_03205	COG1215	transferase activity, transferring glycosyl groups
H7F27_03210	COG0438	transferase activity, transferring glycosyl groups
H7F27_03215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F27_03220	COG1316	TRANSCRIPTIONal
H7F27_03225	COG1739	Uncharacterized protein family UPF0029
H7F27_03230	COG4585	Histidine kinase
H7F27_03235	COG2197	response regulator
H7F27_03240	COG1307	EDD domain protein, DegV family
H7F27_03245	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
H7F27_03255	COG1040	competence protein
H7F27_03265	COG2747	anti-sigma28 factor FlgM
H7F27_03270	COG3418	PFAM FlgN family protein
H7F27_03275	COG1256	bacterial-type flagellum assembly
H7F27_03275	COG4786	Flagellar basal body rod
H7F27_03280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F27_03290	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
H7F27_03295	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
H7F27_03300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H7F27_03305	COG1334	flagellar protein FlaG
H7F27_03310	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H7F27_03315	COG1516	flagellar protein fliS
H7F27_03330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H7F27_03335	COG0653	protein targeting
H7F27_03345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F27_03350	COG2010	Cytochrome c
H7F27_03355	COG2884	Cell division ATP-binding protein ftsE
H7F27_03360	COG2177	Part of the ABC transporter FtsEX involved in
H7F27_03365	COG3409	Peptidoglycan-binding domain 1 protein
H7F27_03365	COG0793	Belongs to the peptidase S41A family
H7F27_03375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F27_03380	COG2814	Major facilitator Superfamily
H7F27_03385	COG1309	transcriptional regulator
H7F27_03390	COG3848	Pyruvate phosphate dikinase
H7F27_03390	COG0574	Belongs to the PEP-utilizing enzyme family
H7F27_03395	COG4897	Protein conserved in bacteria
H7F27_03405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7F27_03420	COG3595	metallopeptidase activity
H7F27_03425	COG1983	PspC domain protein
H7F27_03430	COG1950	PFAM Membrane protein of
H7F27_03435	COG2814	Major facilitator Superfamily
H7F27_03440	COG1846	Transcriptional regulator
H7F27_03450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7F27_03455	COG2188	Transcriptional regulator
H7F27_03460	COG0363	glucosamine-6-phosphate deaminase activity
H7F27_03465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H7F27_03470	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H7F27_03475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H7F27_03480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
H7F27_03485	COG0546	phosphoglycolate phosphatase activity
H7F27_03490	COG0110	maltose O-acetyltransferase activity
H7F27_03495	COG5297	Belongs to the glycosyl hydrolase family 6
H7F27_03500	COG4990	cell redox homeostasis
H7F27_03505	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H7F27_03510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7F27_03515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7F27_03520	COG0131	Imidazoleglycerol-phosphate dehydratase
H7F27_03525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7F27_03530	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H7F27_03535	COG0107	imidazoleglycerol-phosphate synthase activity
H7F27_03540	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7F27_03540	COG0140	phosphoribosyl-ATP diphosphatase activity
H7F27_03560	COG1132	(ABC) transporter
H7F27_03565	COG0457	Tetratricopeptide repeat
H7F27_03570	COG0791	NLP P60 protein
H7F27_03570	COG3883	PFAM NLP P60 protein
H7F27_03575	COG0492	ferredoxin-NADP+ reductase activity
H7F27_03580	COG1051	belongs to the nudix hydrolase family
H7F27_03585	COG1660	Displays ATPase and GTPase activities
H7F27_03590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H7F27_03595	COG1481	regulation of sporulation
H7F27_03600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_03605	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H7F27_03615	COG0745	RESPONSE REGULATOR receiver
H7F27_03620	COG5002	protein histidine kinase activity
H7F27_03625	COG1136	(ABC) transporter
H7F27_03630	COG0577	efflux transmembrane transporter activity
H7F27_03635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F27_03640	COG0288	reversible hydration of carbon dioxide
H7F27_03645	COG0659	secondary active sulfate transmembrane transporter activity
H7F27_03650	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F27_03655	COG1611	Belongs to the LOG family
H7F27_03670	COG0277	FAD linked oxidase domain protein
H7F27_03680	COG2076	Multidrug Resistance protein
H7F27_03685	COG2076	Multidrug Resistance protein
H7F27_03690	COG1309	transcriptional regulator
H7F27_03695	COG0531	amino acid
H7F27_03700	COG1621	beta-fructofuranosidase activity
H7F27_03705	COG1621	beta-fructofuranosidase activity
H7F27_03710	COG0640	Transcriptional regulator
H7F27_03715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H7F27_03720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F27_03730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F27_03735	COG1794	racemase activity, acting on amino acids and derivatives
H7F27_03745	COG3479	Phenolic acid decarboxylase
H7F27_03755	COG2272	Belongs to the type-B carboxylesterase lipase family
H7F27_03760	COG1396	sequence-specific DNA binding
H7F27_03765	COG3944	biosynthesis protein
H7F27_03770	COG0489	protein tyrosine kinase activity
H7F27_03775	COG1086	Polysaccharide biosynthesis protein
H7F27_03780	COG0438	transferase activity, transferring glycosyl groups
H7F27_03785	COG1215	transferase activity, transferring glycosyl groups
H7F27_03790	COG0438	transferase activity, transferring glycosyl groups
H7F27_03800	COG1216	Glycosyl transferase, family 2
H7F27_03805	COG5039	Polysaccharide pyruvyl transferase
H7F27_03810	COG1216	Glycosyl transferase, family 2
H7F27_03815	COG2244	polysaccharide biosynthetic process
H7F27_03820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7F27_03825	COG0110	maltose O-acetyltransferase activity
H7F27_03830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F27_03835	COG5039	Polysaccharide pyruvyl transferase
H7F27_03845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
H7F27_03850	COG1620	l-lactate permease
H7F27_03855	COG2186	Transcriptional regulator
H7F27_03860	COG1609	Transcriptional regulator
H7F27_03865	COG2182	Extracellular solute-binding protein
H7F27_03870	COG1175	transmembrane transport
H7F27_03875	COG3833	ABC-type maltose transport systems, permease component
H7F27_03880	COG1874	Beta-galactosidase
H7F27_03885	COG3867	Arabinogalactan endo-beta-1,4-galactanase
H7F27_03890	COG2208	phosphoserine phosphatase activity
H7F27_03895	COG0596	Alpha beta hydrolase
H7F27_03900	COG1131	(ABC) transporter
H7F27_03905	COG0842	Transport permease protein
H7F27_03910	COG4585	Histidine kinase
H7F27_03915	COG2197	response regulator
H7F27_03920	COG0247	lactate metabolic process
H7F27_03925	COG1139	Iron-sulfur cluster binding protein
H7F27_03930	COG1556	Lactate utilization protein
H7F27_03935	COG3858	chitin binding
H7F27_03940	COG1113	amino acid transport
H7F27_03945	COG0697	spore germination
H7F27_03950	COG0583	DNA-binding transcription factor activity
H7F27_03960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F27_03965	COG1609	Transcriptional regulator
H7F27_03970	COG2814	Major facilitator Superfamily
H7F27_03975	COG2390	Transcriptional regulator
H7F27_03980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F27_03990	COG0126	phosphoglycerate kinase activity
H7F27_03995	COG0149	triose-phosphate isomerase activity
H7F27_04000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7F27_04010	COG2234	aminopeptidase activity
H7F27_04020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F27_04025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F27_04045	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F27_04060	COG0456	acetyltransferase
H7F27_04065	COG4640	response to antibiotic
H7F27_04070	COG3064	Membrane
H7F27_04080	COG1510	regulation of RNA biosynthetic process
H7F27_04085	COG1125	glycine betaine transport
H7F27_04085	COG0517	IMP dehydrogenase activity
H7F27_04090	COG1174	glycine betaine transport
H7F27_04095	COG1732	Glycine betaine
H7F27_04100	COG1174	glycine betaine transport
H7F27_04105	COG0640	Transcriptional regulator
H7F27_04110	COG5658	integral membrane protein
H7F27_04130	COG1510	regulation of RNA biosynthetic process
H7F27_04135	COG0517	IMP dehydrogenase activity
H7F27_04135	COG1125	glycine betaine transport
H7F27_04140	COG1174	glycine betaine transport
H7F27_04145	COG1732	Glycine betaine
H7F27_04150	COG1174	glycine betaine transport
H7F27_04155	COG0840	transmembrane signaling receptor activity
H7F27_04160	COG1733	regulation of RNA biosynthetic process
H7F27_04165	COG1396	sequence-specific DNA binding
H7F27_04170	COG1396	sequence-specific DNA binding
H7F27_04175	COG1476	TRANSCRIPTIONal
H7F27_04180	COG0596	Alpha beta hydrolase
H7F27_04185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F27_04190	COG1647	Serine aminopeptidase, S33
H7F27_04195	COG0557	exoribonuclease II activity
H7F27_04200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H7F27_04210	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_04215	COG1309	transcriptional regulator
H7F27_04220	COG2076	Multidrug Resistance protein
H7F27_04230	COG0697	spore germination
H7F27_04235	COG1802	Transcriptional regulator
H7F27_04240	COG1289	transmembrane transporter activity
H7F27_04245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F27_04250	COG0673	inositol 2-dehydrogenase activity
H7F27_04255	COG1937	Protein conserved in bacteria
H7F27_04260	COG2608	mercury ion transmembrane transporter activity
H7F27_04265	COG2217	Heavy metal translocating P-type atpase
H7F27_04270	COG2217	Heavy metal translocating P-type atpase
H7F27_04275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7F27_04280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H7F27_04290	COG2860	membrane
H7F27_04300	COG3973	AAA domain
H7F27_04305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F27_04310	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F27_04315	COG0025	NhaP-type Na H and K H
H7F27_04330	COG0656	L-ascorbic acid biosynthetic process
H7F27_04335	COG4149	molybdate abc transporter
H7F27_04340	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7F27_04345	COG1910	domain protein
H7F27_04350	COG1368	sulfuric ester hydrolase activity
H7F27_04355	COG1988	membrane-bound metal-dependent
H7F27_04365	COG0531	amino acid
H7F27_04370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F27_04375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_04380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_04385	COG1120	ATPase activity
H7F27_04390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F27_04395	COG1136	(ABC) transporter
H7F27_04400	COG0577	efflux transmembrane transporter activity
H7F27_04410	COG2140	Oxalate decarboxylase
H7F27_04420	COG1191	sigma factor activity
H7F27_04430	COG0745	RESPONSE REGULATOR receiver
H7F27_04435	COG2205	protein histidine kinase activity
H7F27_04440	COG3386	PFAM SMP-30 Gluconolaconase
H7F27_04445	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_04450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F27_04455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_04460	COG1120	ATPase activity
H7F27_04465	COG2096	Adenosyltransferase
H7F27_04470	COG2814	Major facilitator Superfamily
H7F27_04475	COG4758	membrane
H7F27_04480	COG1842	Phage shock protein A
H7F27_04485	COG3595	metallopeptidase activity
H7F27_04490	COG4758	membrane
H7F27_04495	COG4585	Histidine kinase
H7F27_04500	COG2197	response regulator
H7F27_04510	COG0814	amino acid
H7F27_04515	COG0697	spore germination
H7F27_04525	COG0114	fumarate hydratase activity
H7F27_04530	COG1309	transcriptional regulator
H7F27_04540	COG2205	protein histidine kinase activity
H7F27_04540	COG2770	Histidine kinase
H7F27_04545	COG0745	RESPONSE REGULATOR receiver
H7F27_04550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F27_04555	COG0783	Belongs to the Dps family
H7F27_04560	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_04575	COG1120	ATPase activity
H7F27_04585	COG0583	DNA-binding transcription factor activity
H7F27_04590	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_04595	COG1942	4-Oxalocrotonate Tautomerase
H7F27_04600	COG0477	Major facilitator Superfamily
H7F27_04605	COG1846	Transcriptional regulator
H7F27_04610	COG5577	PFAM Coat F domain
H7F27_04620	COG0506	proline dehydrogenase activity
H7F27_04630	COG1024	Enoyl-CoA hydratase
H7F27_04630	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F27_04635	COG0183	Belongs to the thiolase family
H7F27_04640	COG1960	acyl-CoA dehydrogenase activity
H7F27_04645	COG1393	Belongs to the ArsC family
H7F27_04650	COG0509	glycine decarboxylation via glycine cleavage system
H7F27_04660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F27_04665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_04675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7F27_04680	COG2011	ABC-type metal ion transport system permease component
H7F27_04685	COG1464	Belongs to the NlpA lipoprotein family
H7F27_04690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F27_04700	COG0396	ATPase activity
H7F27_04705	COG0719	Fe-S assembly protein
H7F27_04710	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F27_04715	COG0822	iron-sulfur transferase activity
H7F27_04720	COG0719	Fe-S assembly protein
H7F27_04735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F27_04740	COG0322	excinuclease ABC activity
H7F27_04745	COG2222	sugar isomerase
H7F27_04750	COG1653	transport
H7F27_04755	COG1175	transmembrane transport
H7F27_04760	COG0395	ABC-type sugar transport system, permease component
H7F27_04765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F27_04770	COG2188	Transcriptional regulator
H7F27_04775	COG3842	ATPase activity
H7F27_04780	COG2356	endonuclease I
H7F27_04790	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7F27_04795	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
H7F27_04800	COG2068	MobA-Related Protein
H7F27_04805	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
H7F27_04810	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7F27_04815	COG2080	2 iron, 2 sulfur cluster binding
H7F27_04825	COG2351	hydroxyisourate hydrolase activity
H7F27_04830	COG3648	Uricase
H7F27_04830	COG3195	allantoin biosynthetic process
H7F27_04835	COG2233	PERMEase
H7F27_04840	COG2233	PERMEase
H7F27_04845	COG2508	Transcriptional regulator
H7F27_04850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F27_04860	COG1801	Protein of unknown function DUF72
H7F27_04865	COG0730	response to heat
H7F27_04870	COG0737	Belongs to the 5'-nucleotidase family
H7F27_04875	COG3377	Domain of unknown function (DUF1805)
H7F27_04885	COG0739	heme binding
H7F27_04900	COG4470	Protein conserved in bacteria
H7F27_04905	COG2445	Protein of unknown function DUF86
H7F27_04910	COG0647	UMP catabolic process
H7F27_04915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F27_04920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F27_04925	COG0460	homoserine dehydrogenase
H7F27_04930	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7F27_04935	COG0083	homoserine kinase activity
H7F27_04940	COG0823	Involved in the tonB-independent uptake of proteins
H7F27_04940	COG1506	peptidase
H7F27_04940	COG4946	Tricorn protease homolog
H7F27_04945	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H7F27_04950	COG4837	Protein of unknown function (DUF1462)
H7F27_04955	COG1252	NADH dehydrogenase
H7F27_04960	COG4844	belongs to the
H7F27_04965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H7F27_04970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H7F27_04975	COG0316	Belongs to the HesB IscA family
H7F27_04980	COG0516	GMP reductase activity
H7F27_04990	COG0492	ferredoxin-NADP+ reductase activity
H7F27_04995	COG1252	NADH dehydrogenase
H7F27_05010	COG3584	3D domain protein
H7F27_05015	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
H7F27_05020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H7F27_05025	COG2056	Na+-H+ antiporter family
H7F27_05030	COG1268	BioY protein
H7F27_05035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F27_05040	COG2819	hydrolase of the alpha beta superfamily
H7F27_05045	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_05050	COG1169	isochorismate synthase
H7F27_05055	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7F27_05060	COG1535	isochorismatase
H7F27_05060	COG3433	isochorismatase activity
H7F27_05065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_05070	COG3251	PFAM MbtH domain protein
H7F27_05075	COG5634	Uncharacterized conserved protein (DUF2278)
H7F27_05080	COG0686	Belongs to the AlaDH PNT family
H7F27_05085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F27_05085	COG2508	Transcriptional regulator
H7F27_05090	COG4842	Belongs to the WXG100 family
H7F27_05095	COG5417	Belongs to the EsaB family
H7F27_05100	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F27_05105	COG1674	ftsk spoiiie
H7F27_05105	COG0433	COG0433 Predicted ATPase
H7F27_05110	COG1511	domain protein
H7F27_05120	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_05125	COG1418	mRNA catabolic process
H7F27_05135	COG0628	permease
H7F27_05150	COG5506	Protein of unknown function (DUF1694)
H7F27_05160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H7F27_05165	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H7F27_05180	COG0142	geranyltranstransferase activity
H7F27_05190	COG4585	Histidine kinase
H7F27_05195	COG2197	response regulator
H7F27_05200	COG2050	protein possibly involved in aromatic compounds catabolism
H7F27_05205	COG1320	monovalent cation:proton antiporter activity
H7F27_05210	COG2212	antiporter activity
H7F27_05215	COG1863	multisubunit Na H antiporter MnhE subunit
H7F27_05220	COG0651	ATP synthesis coupled electron transport
H7F27_05225	COG1006	Multisubunit Na H antiporter MnhC subunit
H7F27_05230	COG2111	Na H antiporter
H7F27_05235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F27_05235	COG2111	Na H antiporter
H7F27_05245	COG3493	citrate carrier protein
H7F27_05250	COG1079	Belongs to the binding-protein-dependent transport system permease family
H7F27_05255	COG4603	Belongs to the binding-protein-dependent transport system permease family
H7F27_05260	COG3845	ABC transporter
H7F27_05265	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F27_05270	COG4565	transcriptional regulatory protein
H7F27_05275	COG3290	protein histidine kinase activity
H7F27_05285	COG3011	Protein conserved in bacteria
H7F27_05290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F27_05295	COG2814	Major facilitator Superfamily
H7F27_05300	COG5018	Exonuclease
H7F27_05310	COG2205	protein histidine kinase activity
H7F27_05315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H7F27_05325	COG2267	carboxylic ester hydrolase activity
H7F27_05330	COG1522	sequence-specific DNA binding
H7F27_05335	COG0436	Aminotransferase
H7F27_05340	COG1098	S1 RNA binding domain
H7F27_05345	COG2155	Conserved Protein
H7F27_05350	COG1979	alcohol dehydrogenase
H7F27_05355	COG1979	alcohol dehydrogenase
H7F27_05360	COG0166	Belongs to the GPI family
H7F27_05375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7F27_05390	COG2738	Putative neutral zinc metallopeptidase
H7F27_05395	COG1253	flavin adenine dinucleotide binding
H7F27_05400	COG0366	Alpha amylase catalytic
H7F27_05405	COG0432	Pfam Uncharacterised protein family UPF0047
H7F27_05410	COG2070	2-Nitropropane dioxygenase
H7F27_05425	COG0840	transmembrane signaling receptor activity
H7F27_05430	COG0840	transmembrane signaling receptor activity
H7F27_05435	COG0840	transmembrane signaling receptor activity
H7F27_05440	COG0840	transmembrane signaling receptor activity
H7F27_05445	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_05445	COG3347	Dehydrogenase
H7F27_05450	COG1349	DNA-binding transcription factor activity
H7F27_05455	COG1070	Carbohydrate kinase
H7F27_05460	COG3254	rhamnose metabolic process
H7F27_05465	COG4806	L-rhamnose isomerase
H7F27_05470	COG0673	inositol 2-dehydrogenase activity
H7F27_05475	COG0628	permease
H7F27_05480	COG1968	undecaprenyl-diphosphatase activity
H7F27_05490	COG5553	Cysteine dioxygenase type I
H7F27_05495	COG0477	Major facilitator Superfamily
H7F27_05500	COG1705	Flagellar rod assembly protein muramidase FlgJ
H7F27_05505	COG4682	membrane
H7F27_05510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F27_05515	COG0569	domain protein
H7F27_05525	COG1510	regulation of RNA biosynthetic process
H7F27_05530	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_05535	COG1454	alcohol dehydrogenase
H7F27_05545	COG2318	DinB family
H7F27_05550	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7F27_05555	COG2268	Band 7 protein
H7F27_05560	COG1247	-acetyltransferase
H7F27_05565	COG3859	Proton-coupled thiamine transporter YuaJ
H7F27_05690	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H7F27_05695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F27_05700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H7F27_05705	COG0297	glycogen (starch) synthase activity
H7F27_05710	COG0058	SHG alpha-glucan phosphorylase activity
H7F27_05715	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
H7F27_05720	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F27_05725	COG1169	isochorismate synthase
H7F27_05730	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H7F27_05735	COG0596	Alpha beta hydrolase
H7F27_05740	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H7F27_05745	COG0318	PFAM AMP-dependent synthetase and ligase
H7F27_05750	COG4948	Mandelate Racemase Muconate Lactonizing
H7F27_05755	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F27_05760	COG1121	(ABC) transporter
H7F27_05765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F27_05765	COG1321	iron dependent repressor
H7F27_05770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F27_05780	COG1294	oxidase, subunit
H7F27_05785	COG1271	oxidase subunit
H7F27_05790	COG0254	rRNA binding
H7F27_05795	COG0288	reversible hydration of carbon dioxide
H7F27_05800	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H7F27_05805	COG1854	S-ribosylhomocysteine lyase activity
H7F27_05820	COG0783	Belongs to the Dps family
H7F27_05825	COG4824	toxin secretion phage lysis holin
H7F27_05830	COG0494	nUDIX hydrolase
H7F27_05835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F27_05840	COG1116	anion transmembrane transporter activity
H7F27_05845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F27_05850	COG1506	peptidase
H7F27_05860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H7F27_05865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H7F27_05870	COG0367	asparagine synthase
H7F27_05875	COG1113	amino acid transport
H7F27_05880	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7F27_05885	COG2267	carboxylic ester hydrolase activity
H7F27_05895	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
H7F27_05900	COG1242	4 iron, 4 sulfur cluster binding
H7F27_05915	COG1725	Transcriptional regulator
H7F27_05920	COG1131	(ABC) transporter
H7F27_05935	COG1136	(ABC) transporter
H7F27_05940	COG0577	efflux transmembrane transporter activity
H7F27_05945	COG0745	RESPONSE REGULATOR receiver
H7F27_05950	COG2205	protein histidine kinase activity
H7F27_05955	COG1136	(ABC) transporter
H7F27_05960	COG0577	efflux transmembrane transporter activity
H7F27_05965	COG2433	Pfam Transposase IS66
H7F27_05970	COG2814	Major facilitator Superfamily
H7F27_05975	COG2202	Pas domain
H7F27_05975	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_05985	COG0495	leucyl-tRNA aminoacylation
H7F27_05990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F27_05995	COG1486	melibiose metabolic process
H7F27_06000	COG0395	ABC-type sugar transport system, permease component
H7F27_06005	COG1175	transmembrane transport
H7F27_06010	COG1653	transport
H7F27_06015	COG1609	Transcriptional regulator
H7F27_06020	COG1073	alpha beta
H7F27_06030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F27_06035	COG0156	8-amino-7-oxononanoate synthase activity
H7F27_06045	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H7F27_06050	COG2124	cytochrome p450
H7F27_06055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F27_06060	COG0395	ABC-type sugar transport system, permease component
H7F27_06065	COG1653	transport
H7F27_06070	COG2207	Transcriptional regulator
H7F27_06075	COG4209	transmembrane transport
H7F27_06080	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F27_06085	COG1653	transport
H7F27_06090	COG0673	inositol 2-dehydrogenase activity
H7F27_06095	COG5578	integral membrane protein
H7F27_06105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7F27_06110	COG2081	HI0933 family
H7F27_06115	COG2244	polysaccharide biosynthetic process
H7F27_06120	COG1187	pseudouridine synthase activity
H7F27_06125	COG1349	DNA-binding transcription factor activity
H7F27_06130	COG1131	(ABC) transporter
H7F27_06135	COG4473	ABC transporter
H7F27_06140	COG2252	PERMEase
H7F27_06145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F27_06150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F27_06155	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F27_06165	COG1597	lipid kinase activity
H7F27_06170	COG1523	belongs to the glycosyl hydrolase 13 family
H7F27_06175	COG0510	thiamine kinase activity
H7F27_06185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7F27_06190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_06195	COG0281	malic enzyme
H7F27_06200	COG5584	Small secreted protein
H7F27_06205	COG1363	Peptidase, m42
H7F27_06220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_06225	COG4848	Belongs to the UPF0354 family
H7F27_06230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F27_06235	COG1674	ftsk spoiiie
H7F27_06240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7F27_06245	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H7F27_06250	COG4980	gas vesicle protein
H7F27_06255	COG3118	belongs to the thioredoxin family
H7F27_06260	COG1605	Chorismate mutase
H7F27_06260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
H7F27_06265	COG1609	Transcriptional regulator
H7F27_06270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F27_06275	COG1360	Flagellar Motor Protein
H7F27_06280	COG0123	including yeast histone deacetylase and acetoin utilization protein
H7F27_06290	COG0454	-acetyltransferase
H7F27_06295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F27_06300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7F27_06310	COG2203	Gaf domain
H7F27_06310	COG2199	diguanylate cyclase activity
H7F27_06315	COG1956	GAF domain-containing protein
H7F27_06320	COG1309	transcriptional regulator
H7F27_06325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F27_06330	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
H7F27_06335	COG1114	Component of the transport system for branched-chain amino acids
H7F27_06340	COG1104	cysteine desulfurase activity
H7F27_06345	COG0301	tRNA thio-modification
H7F27_06355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7F27_06360	COG1574	metal-dependent hydrolase with the TIM-barrel fold
H7F27_06365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F27_06370	COG0616	signal peptide processing
H7F27_06375	COG1714	RDD family
H7F27_06385	COG3874	Sporulation protein YtfJ
H7F27_06390	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
H7F27_06395	COG0827	DNA restriction-modification system
H7F27_06400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7F27_06405	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7F27_06410	COG0137	argininosuccinate synthase activity
H7F27_06415	COG0165	Argininosuccinate lyase
H7F27_06420	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_06425	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F27_06430	COG0583	DNA-binding transcription factor activity
H7F27_06435	COG0454	-acetyltransferase
H7F27_06440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F27_06445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F27_06450	COG0765	amino acid transport
H7F27_06455	COG0765	amino acid transport
H7F27_06460	COG1126	abc transporter atp-binding protein
H7F27_06465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F27_06470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7F27_06475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F27_06480	COG0196	riboflavin kinase activity
H7F27_06485	COG1473	amidohydrolase
H7F27_06490	COG0730	response to heat
H7F27_06495	COG4109	DRTGG domain
H7F27_06505	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H7F27_06525	COG0587	DNA-directed DNA polymerase activity
H7F27_06530	COG0281	malic enzyme
H7F27_06535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H7F27_06540	COG0825	malonyl-CoA metabolic process
H7F27_06545	COG0205	6-phosphofructokinase activity
H7F27_06550	COG0469	pyruvate kinase activity
H7F27_06555	COG3030	protein affecting phage T7 exclusion by the F plasmid
H7F27_06560	COG0628	permease
H7F27_06565	COG2707	UPF0756 membrane protein
H7F27_06570	COG0372	Belongs to the citrate synthase family
H7F27_06575	COG0538	isocitrate dehydrogenase activity
H7F27_06580	COG0039	L-malate dehydrogenase activity
H7F27_06585	COG0745	RESPONSE REGULATOR receiver
H7F27_06590	COG5002	protein histidine kinase activity
H7F27_06595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F27_06595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F27_06600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H7F27_06605	COG1971	Probably functions as a manganese efflux pump
H7F27_06610	COG0237	dephospho-CoA kinase activity
H7F27_06615	COG0656	L-ascorbic acid biosynthetic process
H7F27_06620	COG2814	Major facilitator Superfamily
H7F27_06625	COG1733	regulation of RNA biosynthetic process
H7F27_06630	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7F27_06635	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H7F27_06640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7F27_06645	COG3611	Membrane attachment protein
H7F27_06650	COG1484	DNA-dependent DNA replication
H7F27_06655	COG0398	Pfam SNARE associated Golgi protein
H7F27_06665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H7F27_06670	COG1011	Hydrolase
H7F27_06675	COG3275	phosphorelay sensor kinase activity
H7F27_06680	COG3279	Response regulator of the LytR AlgR family
H7F27_06685	COG1380	Effector of murein hydrolase LrgA
H7F27_06690	COG1346	cytolysis
H7F27_06700	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H7F27_06705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H7F27_06710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H7F27_06715	COG3326	Membrane
H7F27_06725	COG1363	Peptidase, m42
H7F27_06730	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F27_06735	COG2160	L-arabinose isomerase activity
H7F27_06740	COG1069	ribulokinase activity
H7F27_06745	COG0235	Class ii aldolase
H7F27_06750	COG0647	UMP catabolic process
H7F27_06755	COG0371	Dehydrogenase
H7F27_06760	COG1653	transport
H7F27_06765	COG1175	transmembrane transport
H7F27_06770	COG0395	ABC-type sugar transport system, permease component
H7F27_06775	COG3534	alpha-L-arabinofuranosidase
H7F27_06780	COG1695	Transcriptional regulator
H7F27_06795	COG1966	Carbon starvation protein
H7F27_06800	COG0346	lactoylglutathione lyase activity
H7F27_06805	COG0247	lactate metabolic process
H7F27_06810	COG0277	FAD linked oxidase domain protein
H7F27_06835	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H7F27_06840	COG0072	phenylalanine-tRNA ligase activity
H7F27_06840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F27_06845	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F27_06850	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H7F27_06855	COG1286	toxin biosynthetic process
H7F27_06860	COG1796	DNA polymerase
H7F27_06860	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H7F27_06865	COG1193	negative regulation of DNA recombination
H7F27_06870	COG3766	membrane
H7F27_06875	COG0318	PFAM AMP-dependent synthetase and ligase
H7F27_06880	COG1309	transcriptional regulator
H7F27_06885	COG1024	Enoyl-CoA hydratase
H7F27_06890	COG2086	electron transfer activity
H7F27_06895	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
H7F27_06900	COG3534	alpha-L-arabinofuranosidase
H7F27_06905	COG3118	belongs to the thioredoxin family
H7F27_06910	COG0322	excinuclease ABC activity
H7F27_06920	COG0527	aspartate kinase activity
H7F27_06925	COG1719	4-vinyl reductase, 4VR
H7F27_06930	COG2009	succinate dehydrogenase
H7F27_06935	COG1053	succinate dehydrogenase
H7F27_06940	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7F27_06945	COG0824	Thioesterase
H7F27_06950	COG2197	response regulator
H7F27_06955	COG1846	Transcriptional regulator
H7F27_06960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7F27_06965	COG5401	PFAM Sporulation and spore germination
H7F27_06970	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H7F27_06975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H7F27_06980	COG0622	Phosphoesterase
H7F27_06990	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
H7F27_07000	COG0454	-acetyltransferase
H7F27_07010	COG0028	Belongs to the TPP enzyme family
H7F27_07015	COG0440	acetolactate synthase activity
H7F27_07020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H7F27_07025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F27_07030	COG0473	3-isopropylmalate dehydrogenase activity
H7F27_07035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H7F27_07040	COG0066	3-isopropylmalate dehydratase activity
H7F27_07045	COG0457	Tetratricopeptide repeat
H7F27_07045	COG1477	protein flavinylation
H7F27_07050	COG0544	peptidyl-prolyl cis-trans isomerase activity
H7F27_07055	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H7F27_07060	COG0470	DNA polymerase III
H7F27_07060	COG1067	ATP-dependent peptidase activity
H7F27_07065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H7F27_07070	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H7F27_07080	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H7F27_07085	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F27_07090	COG0181	hydroxymethylbilane synthase activity
H7F27_07095	COG1587	Uroporphyrinogen-III synthase
H7F27_07100	COG0113	porphobilinogen synthase activity
H7F27_07105	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F27_07110	COG1388	LysM domain
H7F27_07115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F27_07125	COG0525	valine-tRNA ligase activity
H7F27_07130	COG0285	dihydrofolate synthase activity
H7F27_07135	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H7F27_07145	COG0424	maF-like protein
H7F27_07150	COG2003	Belongs to the UPF0758 family
H7F27_07155	COG1077	Cell shape determining protein MreB Mrl
H7F27_07165	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7F27_07170	COG0850	regulation of cytokinetic process
H7F27_07175	COG2894	cell division
H7F27_07180	COG0739	heme binding
H7F27_07185	COG1994	Peptidase M50
H7F27_07190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H7F27_07195	COG2868	ribosomal protein
H7F27_07200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H7F27_07210	COG3290	protein histidine kinase activity
H7F27_07215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H7F27_07220	COG4492	Belongs to the UPF0735 family
H7F27_07225	COG0077	Prephenate dehydratase
H7F27_07230	COG1827	regulation of RNA biosynthetic process
H7F27_07235	COG1104	cysteine desulfurase activity
H7F27_07240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H7F27_07245	COG0157	Belongs to the NadC ModD family
H7F27_07250	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7F27_07255	COG1388	LysM domain
H7F27_07270	COG1115	amino acid carrier protein
H7F27_07285	COG2112	serine threonine protein kinase
H7F27_07290	COG0673	inositol 2-dehydrogenase activity
H7F27_07295	COG2814	Major facilitator Superfamily
H7F27_07305	COG0632	four-way junction helicase activity
H7F27_07310	COG2255	four-way junction helicase activity
H7F27_07320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H7F27_07325	COG0343	queuine tRNA-ribosyltransferase activity
H7F27_07330	COG1862	Preprotein translocase
H7F27_07340	COG2323	membrane
H7F27_07345	COG2244	polysaccharide biosynthetic process
H7F27_07355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F27_07355	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7F27_07360	COG0490	domain, Protein
H7F27_07365	COG5416	Lipopolysaccharide assembly protein A domain
H7F27_07370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7F27_07370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
H7F27_07375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F27_07380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7F27_07385	COG1490	D-aminoacyl-tRNA deacylase activity
H7F27_07390	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F27_07390	COG3103	Sh3 type 3 domain protein
H7F27_07390	COG4991	sh3 domain protein
H7F27_07400	COG0124	histidyl-tRNA synthetase
H7F27_07405	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H7F27_07415	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7F27_07420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7F27_07425	COG1959	2 iron, 2 sulfur cluster binding
H7F27_07435	COG0482	sulfurtransferase activity
H7F27_07440	COG0457	Tetratricopeptide repeat
H7F27_07445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7F27_07450	COG3881	PFAM PRC-barrel domain
H7F27_07465	COG0765	amino acid transport
H7F27_07470	COG0765	amino acid transport
H7F27_07475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F27_07480	COG1126	abc transporter atp-binding protein
H7F27_07485	COG0628	permease
H7F27_07490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H7F27_07495	COG4472	Bacterial protein of unknown function (DUF965)
H7F27_07500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7F27_07505	COG3906	Belongs to the UPF0473 family
H7F27_07510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F27_07515	COG4122	O-methyltransferase activity
H7F27_07520	COG0826	peptidase U32
H7F27_07525	COG0826	peptidase U32
H7F27_07530	COG0572	uridine kinase
H7F27_07535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7F27_07540	COG0768	penicillin binding
H7F27_07555	COG2226	methyltransferase
H7F27_07560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7F27_07565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F27_07570	COG0626	cystathionine gamma-synthase activity
H7F27_07580	COG2427	Protein of unknown function (DUF1641)
H7F27_07585	COG3383	formate dehydrogenase (NAD+) activity
H7F27_07590	COG5609	conserved protein (DUF2294)
H7F27_07595	COG2116	formate transmembrane transporter activity
H7F27_07610	COG2226	methyltransferase
H7F27_07615	COG1309	transcriptional regulator
H7F27_07620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F27_07620	COG2124	cytochrome p450
H7F27_07630	COG2755	lipolytic protein G-D-S-L family
H7F27_07630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7F27_07640	COG1595	DNA-templated transcription, initiation
H7F27_07645	COG1378	Sugar-specific transcriptional regulator TrmB
H7F27_07650	COG1280	lysine exporter protein (LysE YggA)
H7F27_07655	COG1113	amino acid transport
H7F27_07660	COG3933	PFAM sigma-54 factor interaction domain-containing protein
H7F27_07660	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F27_07665	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_07670	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_07675	COG3715	PTS system
H7F27_07680	COG3716	PTS system mannose fructose sorbose family IID component
H7F27_07685	COG1621	beta-fructofuranosidase activity
H7F27_07690	COG0693	protein deglycase activity
H7F27_07695	COG1064	alcohol dehydrogenase
H7F27_07700	COG0789	Transcriptional regulator
H7F27_07720	COG1794	racemase activity, acting on amino acids and derivatives
H7F27_07730	COG4991	sh3 domain protein
H7F27_07735	COG4991	sh3 domain protein
H7F27_07745	COG3443	Belongs to the bacterial solute-binding protein 9 family
H7F27_07755	COG4608	Belongs to the ABC transporter superfamily
H7F27_07760	COG0444	Belongs to the ABC transporter superfamily
H7F27_07765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F27_07770	COG0601	transmembrane transport
H7F27_07775	COG0747	negative chemotaxis
H7F27_07790	COG1725	Transcriptional regulator
H7F27_07815	COG2732	(Barnase) inhibitor
H7F27_07845	COG1733	regulation of RNA biosynthetic process
H7F27_07850	COG2085	NADP oxidoreductase coenzyme F420-dependent
H7F27_07860	COG0583	DNA-binding transcription factor activity
H7F27_07865	COG0114	fumarate hydratase activity
H7F27_07880	COG0563	adenylate kinase activity
H7F27_07955	COG1335	isochorismatase
H7F27_07990	COG0662	Cupin 2, conserved barrel domain protein
H7F27_07995	COG1937	Protein conserved in bacteria
H7F27_08000	COG2210	Belongs to the sulfur carrier protein TusA family
H7F27_08005	COG1054	Belongs to the UPF0176 family
H7F27_08010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F27_08010	COG0425	Belongs to the sulfur carrier protein TusA family
H7F27_08020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F27_08020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_08025	COG0425	Belongs to the sulfur carrier protein TusA family
H7F27_08030	COG0730	response to heat
H7F27_08065	COG1230	cation diffusion facilitator family transporter
H7F27_08070	COG2072	flavoprotein involved in K transport
H7F27_08075	COG0457	Tetratricopeptide repeat
H7F27_08080	COG2814	Major facilitator Superfamily
H7F27_08095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F27_08130	COG3209	COG3209 Rhs family protein
H7F27_08140	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
H7F27_08145	COG0398	Pfam SNARE associated Golgi protein
H7F27_08150	COG3409	Peptidoglycan-binding domain 1 protein
H7F27_08150	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F27_08155	COG2755	lipolytic protein G-D-S-L family
H7F27_08165	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
H7F27_08170	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F27_08175	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H7F27_08180	COG1534	Rna-binding protein
H7F27_08185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H7F27_08190	COG1713	HD superfamily hydrolase involved in NAD metabolism
H7F27_08195	COG0799	negative regulation of ribosome biogenesis
H7F27_08200	COG2226	methyltransferase
H7F27_08205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F27_08210	COG1555	photosystem II stabilization
H7F27_08210	COG1596	polysaccharide export
H7F27_08215	COG2131	deaminase
H7F27_08235	COG1466	dna polymerase III delta subunit
H7F27_08245	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
H7F27_08250	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F27_08260	COG0481	GTPase activity
H7F27_08265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F27_08270	COG1420	regulation of RNA biosynthetic process
H7F27_08275	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H7F27_08285	COG0484	heat shock protein binding
H7F27_08290	COG2264	protein methyltransferase activity
H7F27_08295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7F27_08300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F27_08305	COG1283	sodium-dependent phosphate transmembrane transporter activity
H7F27_08315	COG1610	YqeY-like protein
H7F27_08320	COG1030	water channel activity
H7F27_08325	COG4864	UPF0365 protein
H7F27_08340	COG0561	phosphatase activity
H7F27_08345	COG1702	phosphate starvation-inducible protein PhoH
H7F27_08350	COG1480	7TM receptor with intracellular HD hydrolase
H7F27_08355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H7F27_08360	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H7F27_08365	COG0295	cytidine deaminase activity
H7F27_08370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7F27_08380	COG1381	Involved in DNA repair and RecF pathway recombination
H7F27_08385	COG0752	glycyl-tRNA synthetase alpha subunit
H7F27_08390	COG0751	glycine-tRNA ligase activity
H7F27_08395	COG0517	IMP dehydrogenase activity
H7F27_08400	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H7F27_08405	COG1671	Belongs to the UPF0178 family
H7F27_08410	COG0358	DNA primase activity
H7F27_08415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H7F27_08420	COG2010	Cytochrome c
H7F27_08425	COG2384	SAM-dependent methyltransferase
H7F27_08430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7F27_08435	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H7F27_08445	COG0513	Belongs to the DEAD box helicase family
H7F27_08450	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H7F27_08460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F27_08465	COG0735	belongs to the Fur family
H7F27_08470	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
H7F27_08475	COG4709	membrane
H7F27_08480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H7F27_08485	COG1388	LysM domain
H7F27_08490	COG5521	maltodextrose utilization protein MalA
H7F27_08495	COG2839	Protein conserved in bacteria
H7F27_08500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F27_08505	COG0477	Major facilitator Superfamily
H7F27_08510	COG0768	penicillin binding
H7F27_08515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7F27_08520	COG0573	inorganic phosphate transmembrane transporter activity
H7F27_08525	COG0581	inorganic phosphate transmembrane transporter activity
H7F27_08530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F27_08535	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F27_08540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7F27_08555	COG0438	transferase activity, transferring glycosyl groups
H7F27_08565	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7F27_08575	COG0705	Rhomboid family
H7F27_08575	COG0457	Tetratricopeptide repeat
H7F27_08580	COG4483	Protein conserved in bacteria
H7F27_08585	COG1940	carbohydrate kinase activity
H7F27_08590	COG1368	sulfuric ester hydrolase activity
H7F27_08595	COG2866	Carboxypeptidase
H7F27_08605	COG0011	TIGRFAM Protein of
H7F27_08615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_08625	COG1393	Belongs to the ArsC family
H7F27_08635	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_08640	COG1253	flavin adenine dinucleotide binding
H7F27_08645	COG0598	Magnesium transport protein CorA
H7F27_08650	COG0517	IMP dehydrogenase activity
H7F27_08655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7F27_08660	COG1459	type II secretion system
H7F27_08665	COG4537	Required for transformation and DNA binding
H7F27_08670	COG4970	Tfp pilus assembly protein FimT
H7F27_08680	COG4940	Competence protein ComGF
H7F27_08705	COG0681	Belongs to the peptidase S26 family
H7F27_08715	COG1396	sequence-specific DNA binding
H7F27_08730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H7F27_08735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H7F27_08740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F27_08745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H7F27_08750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H7F27_08755	COG0095	Lipoate-protein ligase
H7F27_08760	COG1321	iron dependent repressor
H7F27_08765	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F27_08775	COG3872	metal-dependent enzyme
H7F27_08785	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H7F27_08790	COG0006	proline dipeptidase activity
H7F27_08795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H7F27_08805	COG3854	ATPases associated with a variety of cellular activities
H7F27_08845	COG0511	ligase activity, forming carbon-carbon bonds
H7F27_08850	COG0439	Biotin carboxylase
H7F27_08855	COG1302	Protein conserved in bacteria
H7F27_08860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F27_08865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H7F27_08870	COG1570	exodeoxyribonuclease VII activity
H7F27_08875	COG1722	exodeoxyribonuclease VII activity
H7F27_08880	COG0142	geranyltranstransferase activity
H7F27_08885	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H7F27_08890	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
H7F27_08895	COG1438	arginine binding
H7F27_08900	COG0497	DNA recombination
H7F27_08905	COG0750	zinc metalloprotease
H7F27_08910	COG0745	RESPONSE REGULATOR receiver
H7F27_08915	COG1902	pentaerythritol trinitrate reductase activity
H7F27_08930	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F27_08935	COG0584	glycerophosphoryl diester phosphodiesterase
H7F27_08940	COG0183	Belongs to the thiolase family
H7F27_08945	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7F27_08950	COG1960	acyl-CoA dehydrogenase activity
H7F27_08955	COG0372	Belongs to the citrate synthase family
H7F27_08960	COG2079	MmgE PrpD family protein
H7F27_08965	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H7F27_08975	COG3829	transcription factor binding
H7F27_08975	COG3290	protein histidine kinase activity
H7F27_08980	COG0280	phosphate acetyltransferase
H7F27_08990	COG3426	butyrate kinase activity
H7F27_08995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F27_09000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F27_09005	COG0022	dehydrogenase e1 component
H7F27_09010	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F27_09015	COG0789	Transcriptional regulator
H7F27_09015	COG4978	Transcriptional regulator
H7F27_09020	COG2814	Major facilitator Superfamily
H7F27_09025	COG1597	lipid kinase activity
H7F27_09035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F27_09040	COG0765	amino acid transport
H7F27_09045	COG1126	abc transporter atp-binding protein
H7F27_09050	COG4129	membrane
H7F27_09055	COG1376	ErfK ybiS ycfS ynhG family protein
H7F27_09065	COG0346	lactoylglutathione lyase activity
H7F27_09070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F27_09075	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7F27_09080	COG3361	conserved protein (COG2071)
H7F27_09085	COG0706	membrane insertase activity
H7F27_09095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F27_09100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H7F27_09110	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H7F27_09115	COG1234	tRNA 3'-trailer cleavage
H7F27_09130	COG0596	Alpha beta hydrolase
H7F27_09135	COG1902	pentaerythritol trinitrate reductase activity
H7F27_09140	COG4187	Peptidase family M20/M25/M40
H7F27_09145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F27_09150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_09155	COG0300	oxidoreductase activity
H7F27_09160	COG3048	D-serine ammonia-lyase activity
H7F27_09165	COG1072	(Pantothenic acid kinase))
H7F27_09180	COG2211	Major facilitator Superfamily
H7F27_09195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7F27_09205	COG0456	acetyltransferase
H7F27_09210	COG2329	Antibiotic biosynthesis monooxygenase
H7F27_09215	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7F27_09215	COG0456	acetyltransferase
H7F27_09220	COG4918	Iron-sulphur cluster biosynthesis
H7F27_09230	COG1073	alpha beta
H7F27_09240	COG0667	Aldo Keto reductase
H7F27_09250	COG0494	nUDIX hydrolase
H7F27_09255	COG1379	DNA repair
H7F27_09260	COG1396	sequence-specific DNA binding
H7F27_09265	COG0252	asparaginase activity
H7F27_09270	COG1027	Aspartate ammonia-lyase
H7F27_09275	COG1757	Na H antiporter
H7F27_09280	COG0281	malic enzyme
H7F27_09290	COG1300	Membrane
H7F27_09295	COG0735	belongs to the Fur family
H7F27_09305	COG4974	Belongs to the 'phage' integrase family
H7F27_09310	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H7F27_09315	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H7F27_09320	COG1686	Belongs to the peptidase S11 family
H7F27_09325	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_09330	COG2172	sigma factor antagonist activity
H7F27_09335	COG1191	sigma factor activity
H7F27_09355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F27_09370	COG0697	spore germination
H7F27_09375	COG0019	diaminopimelate decarboxylase activity
H7F27_09380	COG4086	secreted protein
H7F27_09385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7F27_09390	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
H7F27_09395	COG0681	Belongs to the peptidase S26 family
H7F27_09405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F27_09405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7F27_09410	COG0307	riboflavin synthase, alpha
H7F27_09415	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F27_09415	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7F27_09420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H7F27_09425	COG0456	acetyltransferase
H7F27_09430	COG1547	Domain of unknown function (DUF309)
H7F27_09440	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7F27_09445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7F27_09455	COG1686	Belongs to the peptidase S11 family
H7F27_09460	COG2715	membrane protein required for spore maturation
H7F27_09465	COG0700	Nucleoside recognition
H7F27_09470	COG1187	pseudouridine synthase activity
H7F27_09475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_09480	COG1333	cytochrome c biogenesis protein
H7F27_09485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H7F27_09490	COG0745	RESPONSE REGULATOR receiver
H7F27_09495	COG5002	protein histidine kinase activity
H7F27_09500	COG1595	DNA-templated transcription, initiation
H7F27_09510	COG0710	3-dehydroquinate dehydratase activity
H7F27_09515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F27_09520	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
H7F27_09525	COG1141	Ferredoxin
H7F27_09530	COG4955	Helix-turn-helix domain
H7F27_09535	COG0514	ATP-dependent DNA helicase (RecQ)
H7F27_09540	COG1266	CAAX protease self-immunity
H7F27_09545	COG1388	LysM domain
H7F27_09555	COG1408	metallophosphoesterase
H7F27_09560	COG4862	establishment of competence for transformation
H7F27_09565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7F27_09570	COG0492	ferredoxin-NADP+ reductase activity
H7F27_09575	COG2339	peptidase activity
H7F27_09580	COG3773	Cell wall hydrolase
H7F27_09580	COG3409	Peptidoglycan-binding domain 1 protein
H7F27_09585	COG2959	enzyme of heme biosynthesis
H7F27_09590	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
H7F27_09600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H7F27_09605	COG0539	negative regulation of cytoplasmic translation
H7F27_09610	COG1304	FMN binding
H7F27_09635	COG1160	GTP binding
H7F27_09640	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H7F27_09655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F27_09660	COG0776	regulation of translation
H7F27_09665	COG0302	gtp cyclohydrolase
H7F27_09675	COG0142	geranyltranstransferase activity
H7F27_09680	COG2226	methyltransferase
H7F27_09685	COG0142	geranyltranstransferase activity
H7F27_09690	COG0105	UTP biosynthetic process
H7F27_09695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H7F27_09700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H7F27_09705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H7F27_09710	COG4401	Chorismate mutase type I
H7F27_09715	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F27_09720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7F27_09730	COG0135	phosphoribosylanthranilate isomerase activity
H7F27_09735	COG0133	tryptophan synthase activity
H7F27_09740	COG0159	tryptophan synthase activity
H7F27_09745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H7F27_09750	COG0287	Prephenate dehydrogenase
H7F27_09755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7F27_09760	COG0457	Tetratricopeptide repeat
H7F27_09765	COG5582	Belongs to the UPF0302 family
H7F27_09775	COG0723	plastoquinol--plastocyanin reductase activity
H7F27_09780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F27_09785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H7F27_09785	COG2010	Cytochrome c
H7F27_09790	COG4347	Protein of unknown function (DUF1405)
H7F27_09800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F27_09805	COG1694	Mazg nucleotide pyrophosphohydrolase
H7F27_09810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H7F27_09815	COG1803	Methylglyoxal synthase
H7F27_09820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F27_09825	COG0438	transferase activity, transferring glycosyl groups
H7F27_09830	COG0617	tRNA 3'-terminal CCA addition
H7F27_09835	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
H7F27_09835	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
H7F27_09840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H7F27_09845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H7F27_09850	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H7F27_09865	COG5353	protein conserved in bacteria
H7F27_09870	COG0436	Aminotransferase
H7F27_09875	COG0017	Asparaginyl-tRNA synthetase
H7F27_09880	COG3935	DnaD domain protein
H7F27_09885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7F27_09895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F27_09895	COG4499	WXG100 protein secretion system (Wss), protein YukC
H7F27_09900	COG3331	DNA recombination
H7F27_09935	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F27_09940	COG2190	(PTS) system
H7F27_09945	COG1205	dead DEAH box helicase
H7F27_09945	COG1111	helicase
H7F27_09950	COG3359	exonuclease
H7F27_09965	COG4474	Belongs to the UPF0398 family
H7F27_09980	COG0116	Belongs to the methyltransferase superfamily
H7F27_09995	COG1199	ATP-dependent helicase activity
H7F27_10000	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_10005	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
H7F27_10010	COG1609	Transcriptional regulator
H7F27_10015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F27_10020	COG0800	Aldolase
H7F27_10030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H7F27_10035	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F27_10040	COG2233	PERMEase
H7F27_10045	COG3424	synthase
H7F27_10050	COG1755	Isoprenylcysteine carboxyl methyltransferase
H7F27_10060	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
H7F27_10075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7F27_10085	COG0328	RNA-DNA hybrid ribonuclease activity
H7F27_10090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H7F27_10095	COG0328	RNA-DNA hybrid ribonuclease activity
H7F27_10115	COG1278	Cold shock
H7F27_10125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F27_10130	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H7F27_10135	COG0386	Belongs to the glutathione peroxidase family
H7F27_10140	COG1418	mRNA catabolic process
H7F27_10145	COG1413	lyase activity
H7F27_10150	COG0129	dihydroxy-acid dehydratase activity
H7F27_10160	COG2136	Putative SAM-dependent methyltransferase
H7F27_10160	COG2521	methyltransferase
H7F27_10170	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7F27_10180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7F27_10185	COG0204	Acyl-transferase
H7F27_10190	COG1272	protein, Hemolysin III
H7F27_10195	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H7F27_10200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7F27_10210	COG1999	signal sequence binding
H7F27_10215	COG2755	lipolytic protein G-D-S-L family
H7F27_10220	COG4698	Protein conserved in bacteria
H7F27_10230	COG0534	Mate efflux family protein
H7F27_10235	COG1846	Transcriptional regulator
H7F27_10240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H7F27_10250	COG1086	Polysaccharide biosynthesis protein
H7F27_10255	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
H7F27_10260	COG4641	Protein conserved in bacteria
H7F27_10275	COG0463	Glycosyl transferase, family 2
H7F27_10280	COG0456	acetyltransferase
H7F27_10290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F27_10295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7F27_10300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7F27_10305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F27_10310	COG0456	acetyltransferase
H7F27_10315	COG1509	lysine 2,3-aminomutase activity
H7F27_10325	COG4479	Belongs to the UPF0346 family
H7F27_10345	COG0671	phosphoesterase, PA-phosphatase related
H7F27_10360	COG0813	purine-nucleoside phosphorylase activity
H7F27_10365	COG1876	peptidase activity
H7F27_10375	COG2226	methyltransferase
H7F27_10380	COG0793	Belongs to the peptidase S41A family
H7F27_10380	COG3409	Peptidoglycan-binding domain 1 protein
H7F27_10385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F27_10395	COG0346	lactoylglutathione lyase activity
H7F27_10400	COG0400	carboxylic ester hydrolase activity
H7F27_10405	COG0778	Nitroreductase
H7F27_10410	COG1733	regulation of RNA biosynthetic process
H7F27_10420	COG1942	4-Oxalocrotonate Tautomerase
H7F27_10440	COG2962	Rard protein
H7F27_10450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F27_10455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
H7F27_10460	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_10465	COG0534	Mate efflux family protein
H7F27_10470	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F27_10475	COG1819	glycosyl
H7F27_10485	COG2032	superoxide dismutase activity
H7F27_10490	COG0714	Associated with various cellular activities
H7F27_10500	COG0567	Dehydrogenase, E1 component
H7F27_10505	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F27_10510	COG0385	Bile acid
H7F27_10515	COG0733	neurotransmitter:sodium symporter activity
H7F27_10520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7F27_10525	COG1657	PFAM Prenyltransferase squalene oxidase
H7F27_10530	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_10545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F27_10550	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7F27_10560	COG0514	ATP-dependent DNA helicase (RecQ)
H7F27_10565	COG3584	3D domain protein
H7F27_10565	COG1388	LysM domain
H7F27_10575	COG2197	response regulator
H7F27_10580	COG4585	Histidine kinase
H7F27_10585	COG3239	Fatty acid desaturase
H7F27_10590	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F27_10605	COG2322	membrane
H7F27_10610	COG0741	lytic transglycosylase activity
H7F27_10615	COG0640	Transcriptional regulator
H7F27_10625	COG2378	regulation of single-species biofilm formation
H7F27_10630	COG3708	Transcriptional regulator
H7F27_10635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_10640	COG1309	transcriptional regulator
H7F27_10645	COG0456	acetyltransferase
H7F27_10650	COG0662	Cupin 2, conserved barrel domain protein
H7F27_10650	COG2207	Transcriptional regulator
H7F27_10655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F27_10665	COG1733	regulation of RNA biosynthetic process
H7F27_10670	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_10705	COG0457	Tetratricopeptide repeat
H7F27_10745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F27_10750	COG2318	DinB family
H7F27_10755	COG3397	chitin binding
H7F27_10770	COG2211	Major facilitator Superfamily
H7F27_10775	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F27_10790	COG1070	Carbohydrate kinase
H7F27_10805	COG1231	oxidoreductase activity
H7F27_10810	COG1525	nuclease
H7F27_10815	COG2814	Major facilitator Superfamily
H7F27_10855	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_10865	COG3619	membrane
H7F27_10870	COG4305	rare lipoprotein A
H7F27_10880	COG0243	molybdopterin cofactor binding
H7F27_10885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7F27_10890	COG1070	Carbohydrate kinase
H7F27_10895	COG2814	Major facilitator Superfamily
H7F27_10905	COG1131	(ABC) transporter
H7F27_10930	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
H7F27_10935	COG0300	oxidoreductase activity
H7F27_10960	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F27_10965	COG0583	DNA-binding transcription factor activity
H7F27_10970	COG0069	glutamate synthase activity
H7F27_10970	COG0070	glutamate synthase
H7F27_10970	COG0067	glutamate synthase
H7F27_10975	COG0493	'glutamate synthase
H7F27_10980	COG0604	alcohol dehydrogenase
H7F27_10985	COG0583	DNA-binding transcription factor activity
H7F27_10990	COG0405	Gamma-glutamyltransferase
H7F27_10995	COG0166	Belongs to the GPI family
H7F27_11000	COG0582	viral genome integration into host DNA
H7F27_11015	COG0534	Mate efflux family protein
H7F27_11020	COG2017	converts alpha-aldose to the beta-anomer
H7F27_11025	COG2027	D-alanyl-D-alanine carboxypeptidase
H7F27_11030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_11040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_11045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_11060	COG1649	PFAM Uncharacterised BCR, COG1649
H7F27_11070	COG1960	acyl-CoA dehydrogenase activity
H7F27_11075	COG0318	PFAM AMP-dependent synthetase and ligase
H7F27_11080	COG0439	Biotin carboxylase
H7F27_11085	COG0511	ligase activity, forming carbon-carbon bonds
H7F27_11090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7F27_11095	COG1024	Enoyl-CoA hydratase
H7F27_11100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7F27_11105	COG2404	hydrolase activity, acting on ester bonds
H7F27_11110	COG0586	Pfam SNARE associated Golgi protein
H7F27_11115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7F27_11120	COG2246	polysaccharide biosynthetic process
H7F27_11135	COG3507	Belongs to the glycosyl hydrolase 43 family
H7F27_11140	COG5520	Belongs to the glycosyl hydrolase 30 family
H7F27_11155	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
H7F27_11160	COG1115	amino acid carrier protein
H7F27_11170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H7F27_11180	COG1832	CoA-binding protein
H7F27_11185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H7F27_11190	COG4841	protein insertion into membrane
H7F27_11200	COG0824	Thioesterase
H7F27_11220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_11225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7F27_11240	COG0071	Belongs to the small heat shock protein (HSP20) family
H7F27_11250	COG4846	Membrane protein involved in cytochrome C biogenesis
H7F27_11255	COG2201	protein-glutamate methylesterase activity
H7F27_11260	COG0785	Cytochrome C biogenesis protein
H7F27_11270	COG3763	UPF0154 protein
H7F27_11280	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7F27_11285	COG4224	UPF0291 protein
H7F27_11290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H7F27_11295	COG1388	LysM domain
H7F27_11300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H7F27_11310	COG0346	lactoylglutathione lyase activity
H7F27_11330	COG4195	phage-related replication protein
H7F27_11360	COG3832	glyoxalase III activity
H7F27_11370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F27_11390	COG5434	Belongs to the glycosyl hydrolase 28 family
H7F27_11395	COG2135	peptidase activity
H7F27_11405	COG3655	Transcriptional regulator
H7F27_11410	COG3739	integral membrane protein
H7F27_11415	COG2720	vancomycin resistance protein
H7F27_11420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F27_11445	COG0726	polysaccharide deacetylase
H7F27_11470	COG0457	Tetratricopeptide repeat
H7F27_11485	COG2273	Hydrolase Family 16
H7F27_11560	COG0583	DNA-binding transcription factor activity
H7F27_11565	COG0697	spore germination
H7F27_11570	COG1388	LysM domain
H7F27_11595	COG0174	glutamine synthetase
H7F27_11600	COG0789	Transcriptional regulator
H7F27_11605	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
H7F27_11610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7F27_11615	COG0464	growth
H7F27_11620	COG1131	(ABC) transporter
H7F27_11625	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F27_11630	COG4112	unkown
H7F27_11635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F27_11640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7F27_11645	COG1780	Probably involved in ribonucleotide reductase function
H7F27_11665	COG1923	regulation of RNA biosynthetic process
H7F27_11670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H7F27_11695	COG1764	response to oxidative stress
H7F27_11700	COG4195	phage-related replication protein
H7F27_11705	COG1404	Belongs to the peptidase S8 family
H7F27_11715	COG2124	cytochrome p450
H7F27_11720	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H7F27_11720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7F27_11720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F27_11720	COG3321	synthase
H7F27_11725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_11725	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_11725	COG3321	synthase
H7F27_11725	COG4221	oxidoreductase activity
H7F27_11730	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_11730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F27_11730	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_11730	COG3321	synthase
H7F27_11730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F27_11735	COG4221	oxidoreductase activity
H7F27_11735	COG3321	synthase
H7F27_11735	COG0300	oxidoreductase activity
H7F27_11735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F27_11740	COG0300	oxidoreductase activity
H7F27_11740	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_11740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_11740	COG0318	PFAM AMP-dependent synthetase and ligase
H7F27_11740	COG3321	synthase
H7F27_11745	COG1024	Enoyl-CoA hydratase
H7F27_11750	COG1024	Enoyl-CoA hydratase
H7F27_11755	COG3425	synthase
H7F27_11760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F27_11765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7F27_11770	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F27_11770	COG2070	2-Nitropropane dioxygenase
H7F27_11775	COG3321	synthase
H7F27_11780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F27_11785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_11790	COG3226	Transcriptional regulator
H7F27_11850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7F27_11855	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H7F27_11865	COG4550	Control of competence regulator ComK, YlbF/YmcA
H7F27_11870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H7F27_11875	COG0156	8-amino-7-oxononanoate synthase activity
H7F27_11880	COG1063	alcohol dehydrogenase
H7F27_11885	COG2359	stage V sporulation protein S
H7F27_11890	COG1692	metallophosphoesterase
H7F27_11895	COG1418	mRNA catabolic process
H7F27_11900	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F27_11905	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H7F27_11910	COG1546	Belongs to the CinA family
H7F27_11910	COG1058	Belongs to the CinA family
H7F27_11915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7F27_11920	COG1426	Protein conserved in bacteria
H7F27_11935	COG0300	oxidoreductase activity
H7F27_11940	COG0612	Peptidase, M16
H7F27_11945	COG0612	Peptidase, M16
H7F27_11950	COG2814	Major facilitator Superfamily
H7F27_11955	COG2188	Transcriptional regulator
H7F27_11960	COG1674	ftsk spoiiie
H7F27_11960	COG4980	gas vesicle protein
H7F27_11970	COG0740	serine-type endopeptidase activity
H7F27_11975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F27_11980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F27_11985	COG0527	aspartate kinase activity
H7F27_11990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H7F27_11995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F27_12000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H7F27_12005	COG1873	PFAM PRC-barrel domain
H7F27_12010	COG0612	Peptidase, M16
H7F27_12015	COG0726	polysaccharide deacetylase
H7F27_12020	COG1185	polyribonucleotide nucleotidyltransferase activity
H7F27_12030	COG0196	riboflavin kinase activity
H7F27_12035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7F27_12040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H7F27_12045	COG1550	Protein conserved in bacteria
H7F27_12050	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H7F27_12055	COG1358	cellular component organization or biogenesis
H7F27_12060	COG2740	Nucleic-acid-binding protein implicated in transcription termination
H7F27_12065	COG0195	Participates in both transcription termination and antitermination
H7F27_12070	COG0779	Required for maturation of 30S ribosomal subunits
H7F27_12075	COG2176	DNA-directed DNA polymerase activity
H7F27_12080	COG0442	prolyl-tRNA aminoacylation
H7F27_12085	COG0750	zinc metalloprotease
H7F27_12090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H7F27_12095	COG4589	Belongs to the CDS family
H7F27_12100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7F27_12105	COG0233	cytoplasmic translational termination
H7F27_12110	COG0528	UMP kinase activity
H7F27_12115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H7F27_12120	COG0052	Belongs to the universal ribosomal protein uS2 family
H7F27_12135	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H7F27_12140	COG1776	CheC inhibitor of MCP methylation
H7F27_12145	COG0835	chemotaxis
H7F27_12155	COG2201	protein-glutamate methylesterase activity
H7F27_12160	COG0455	bacterial-type flagellum organization
H7F27_12165	COG1419	protein localization to endoplasmic reticulum
H7F27_12170	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F27_12175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H7F27_12180	COG1684	flagellar biosynthetic protein fliR
H7F27_12185	COG1987	bacterial-type flagellum assembly
H7F27_12190	COG1338	Plays a role in the flagellum-specific transport system
H7F27_12195	COG3190	flagellar
H7F27_12200	COG2201	protein-glutamate methylesterase activity
H7F27_12205	COG1776	CheC inhibitor of MCP methylation
H7F27_12205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F27_12210	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F27_12215	COG1580	Controls the rotational direction of flagella during chemotaxis
H7F27_12220	COG1582	Flagellar protein (FlbD)
H7F27_12225	COG4786	Flagellar basal body rod
H7F27_12230	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H7F27_12235	COG3144	bacterial-type flagellum assembly
H7F27_12240	COG3334	PFAM MgtE intracellular
H7F27_12245	COG2882	bacterial-type flagellum organization
H7F27_12250	COG1157	protein secretion by the type III secretion system
H7F27_12255	COG1317	bacterial-type flagellum organization
H7F27_12260	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H7F27_12265	COG1766	The M ring may be actively involved in energy transduction
H7F27_12270	COG1677	Flagellar hook-basal body complex protein FliE
H7F27_12275	COG1558	bacterial-type flagellum-dependent cell motility
H7F27_12280	COG1815	bacterial-type flagellum-dependent cell motility
H7F27_12285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H7F27_12290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H7F27_12295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H7F27_12300	COG4974	Belongs to the 'phage' integrase family
H7F27_12305	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
H7F27_12310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F27_12315	COG0758	DNA mediated transformation
H7F27_12320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H7F27_12325	COG0045	succinate-CoA ligase (ADP-forming) activity
H7F27_12330	COG2257	FlhB HrpN YscU SpaS Family
H7F27_12340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7F27_12345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
H7F27_12350	COG0335	large ribosomal subunit rRNA binding
H7F27_12355	COG0336	Belongs to the RNA methyltransferase TrmD family
H7F27_12360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7F27_12370	COG1837	Belongs to the UPF0109 family
H7F27_12375	COG0228	four-way junction DNA binding
H7F27_12380	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7F27_12385	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
H7F27_12395	COG0552	protein localization to endoplasmic reticulum
H7F27_12405	COG0571	ribonuclease III activity
H7F27_12415	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_12420	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7F27_12425	COG0416	fatty acid biosynthetic process
H7F27_12430	COG1349	DNA-binding transcription factor activity
H7F27_12430	COG2050	protein possibly involved in aromatic compounds catabolism
H7F27_12435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7F27_12440	COG1760	l-serine dehydratase
H7F27_12445	COG1760	l-serine dehydratase
H7F27_12450	COG1461	Dihydroxyacetone kinase
H7F27_12455	COG1302	Protein conserved in bacteria
H7F27_12460	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H7F27_12470	COG1564	THIamine pyrophosphokinase
H7F27_12475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7F27_12480	COG1162	GTPase activity
H7F27_12485	COG2815	serine threonine protein kinase
H7F27_12485	COG0515	serine threonine protein kinase
H7F27_12490	COG0631	protein serine/threonine phosphatase activity
H7F27_12495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H7F27_12500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H7F27_12500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H7F27_12505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H7F27_12510	COG0242	peptide deformylase activity
H7F27_12515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7F27_12520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7F27_12525	COG1758	RNA polymerase activity
H7F27_12530	COG0194	GDP metabolic process
H7F27_12540	COG1561	YicC-like family, N-terminal region
H7F27_12545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7F27_12555	COG1648	precorrin-2 dehydrogenase activity
H7F27_12560	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
H7F27_12565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F27_12570	COG0529	Catalyzes the synthesis of activated sulfate
H7F27_12575	COG2046	Belongs to the sulfate adenylyltransferase family
H7F27_12580	COG0306	phosphate transporter
H7F27_12585	COG0175	sulfate reduction
H7F27_12590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H7F27_12595	COG0284	orotidine-5'-phosphate decarboxylase activity
H7F27_12600	COG0167	dihydroorotate dehydrogenase activity
H7F27_12605	COG0543	2 iron, 2 sulfur cluster binding
H7F27_12610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F27_12615	COG0505	Belongs to the CarA family
H7F27_12620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H7F27_12625	COG0540	Belongs to the ATCase OTCase family
H7F27_12630	COG2233	PERMEase
H7F27_12635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H7F27_12640	COG0564	pseudouridine synthase activity
H7F27_12645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H7F27_12650	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7F27_12655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7F27_12660	COG3599	regulation of cell shape
H7F27_12665	COG2302	S4 RNA-binding domain
H7F27_12670	COG0762	integral membrane protein
H7F27_12675	COG1799	cell septum assembly
H7F27_12680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H7F27_12685	COG1496	oxidoreductase activity
H7F27_12690	COG1873	PFAM PRC-barrel domain
H7F27_12695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H7F27_12700	COG1119	ATPase activity
H7F27_12705	COG1191	sigma factor activity
H7F27_12710	COG1191	sigma factor activity
H7F27_12720	COG4412	M6 family metalloprotease domain protein
H7F27_12720	COG1404	Belongs to the peptidase S8 family
H7F27_12725	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7F27_12730	COG0849	cell division
H7F27_12735	COG3856	small basic protein
H7F27_12740	COG3879	Bacterial protein of unknown function (DUF881)
H7F27_12745	COG3879	Bacterial protein of unknown function (DUF881)
H7F27_12750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7F27_12755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H7F27_12760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F27_12765	COG0772	Belongs to the SEDS family
H7F27_12770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H7F27_12775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H7F27_12780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7F27_12785	COG0768	penicillin binding
H7F27_12790	COG0768	penicillin binding
H7F27_12795	COG4839	cell division protein FtsL
H7F27_12800	COG0275	rRNA processing
H7F27_12805	COG2001	Belongs to the MraZ family
H7F27_12810	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
H7F27_12815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F27_12820	COG0454	-acetyltransferase
H7F27_12835	COG1399	metal-binding, possibly nucleic acid-binding protein
H7F27_12840	COG1323	Belongs to the UPF0348 family
H7F27_12850	COG3480	Lon protease (S16) C-terminal proteolytic domain
H7F27_12855	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7F27_12860	COG3314	Sporulation integral membrane protein YlbJ
H7F27_12865	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H7F27_12870	COG0742	ribosomal rna small subunit methyltransferase
H7F27_12875	COG4471	UPF0298 protein
H7F27_12880	COG3679	Belongs to the UPF0342 family
H7F27_12895	COG2340	Cysteine-rich secretory protein family
H7F27_12900	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H7F27_12910	COG3336	cytochrome c oxidase
H7F27_12915	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7F27_12920	COG1845	cytochrome c oxidase, subunit III
H7F27_12925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7F27_12930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7F27_12930	COG2010	Cytochrome c
H7F27_12935	COG0109	protoheme IX farnesyltransferase activity
H7F27_12940	COG1612	heme a metabolic process
H7F27_12945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
H7F27_12950	COG0772	Belongs to the SEDS family
H7F27_12955	COG4838	Belongs to the UPF0358 family
H7F27_12960	COG2066	Belongs to the glutaminase family
H7F27_12965	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H7F27_12970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H7F27_12980	COG4896	Protein conserved in bacteria
H7F27_12990	COG1217	gtp-binding protein TYPA
H7F27_13020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H7F27_13030	COG0483	inositol monophosphate 1-phosphatase activity
H7F27_13040	COG4493	Belongs to the UPF0637 family
H7F27_13045	COG4476	Belongs to the UPF0223 family
H7F27_13050	COG1982	Orn Lys Arg decarboxylase major
H7F27_13060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_13065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7F27_13070	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F27_13075	COG0022	dehydrogenase e1 component
H7F27_13080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F27_13085	COG0497	DNA recombination
H7F27_13095	COG0242	peptide deformylase activity
H7F27_13100	COG0561	phosphatase activity
H7F27_13105	COG5503	Protein of unknown function (DUF1447)
H7F27_13110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H7F27_13115	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F27_13120	COG0569	domain protein
H7F27_13125	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
H7F27_13125	COG2105	PFAM AIG2 family protein
H7F27_13130	COG3852	Histidine kinase
H7F27_13135	COG2002	toxin-antitoxin pair type II binding
H7F27_13140	COG1077	Cell shape determining protein MreB Mrl
H7F27_13150	COG2309	aminopeptidase activity
H7F27_13155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H7F27_13160	COG0488	(ABC) transporter
H7F27_13170	COG0681	Belongs to the peptidase S26 family
H7F27_13175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F27_13175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_13175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F27_13180	COG1105	Belongs to the carbohydrate kinase PfkB family
H7F27_13185	COG1349	DNA-binding transcription factor activity
H7F27_13190	COG0577	efflux transmembrane transporter activity
H7F27_13195	COG1136	(ABC) transporter
H7F27_13200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7F27_13210	COG1132	(ABC) transporter
H7F27_13215	COG1132	(ABC) transporter
H7F27_13220	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H7F27_13230	COG1763	Mo-molybdopterin cofactor biosynthetic process
H7F27_13235	COG0303	'Molybdopterin
H7F27_13240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F27_13245	COG0746	molybdenum cofactor guanylyltransferase activity
H7F27_13260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_13265	COG0450	alkyl hydroperoxide reductase
H7F27_13270	COG0668	transmembrane transport
H7F27_13280	COG1473	amidohydrolase
H7F27_13285	COG2171	N-acyltransferase activity
H7F27_13290	COG0716	FMN binding
H7F27_13300	COG0716	FMN binding
H7F27_13305	COG0583	DNA-binding transcription factor activity
H7F27_13310	COG0517	IMP dehydrogenase activity
H7F27_13320	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
H7F27_13325	COG4703	Protein of unknown function (DUF1797)
H7F27_13330	COG3546	catalase activity
H7F27_13335	COG2200	EAL domain
H7F27_13340	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_13345	COG1408	metallophosphoesterase
H7F27_13350	COG1376	ErfK ybiS ycfS ynhG family protein
H7F27_13355	COG2814	Major facilitator Superfamily
H7F27_13365	COG0835	chemotaxis
H7F27_13365	COG0784	Response regulator, receiver
H7F27_13375	COG0436	Aminotransferase
H7F27_13380	COG4191	Histidine kinase
H7F27_13385	COG0768	penicillin binding
H7F27_13390	COG2340	Cysteine-rich secretory protein family
H7F27_13395	COG2084	Dehydrogenase
H7F27_13400	COG0840	transmembrane signaling receptor activity
H7F27_13405	COG0456	acetyltransferase
H7F27_13410	COG1533	DNA photolyase activity
H7F27_13420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7F27_13425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_13430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_13430	COG1263	PTS System
H7F27_13430	COG2190	(PTS) system
H7F27_13435	COG3711	transcriptional antiterminator
H7F27_13440	COG1609	Transcriptional regulator
H7F27_13445	COG0006	proline dipeptidase activity
H7F27_13455	COG2217	Heavy metal translocating P-type atpase
H7F27_13460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_13465	COG2244	polysaccharide biosynthetic process
H7F27_13470	COG3773	Cell wall hydrolase
H7F27_13480	COG4873	Protein conserved in bacteria
H7F27_13490	COG3858	chitin binding
H7F27_13495	COG1388	LysM domain
H7F27_13500	COG4641	Protein conserved in bacteria
H7F27_13500	COG1388	LysM domain
H7F27_13505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H7F27_13510	COG0602	queuosine metabolic process
H7F27_13515	COG0720	synthase
H7F27_13520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7F27_13525	COG3949	Membrane
H7F27_13530	COG0542	response to heat
H7F27_13535	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H7F27_13540	COG1360	Flagellar Motor Protein
H7F27_13545	COG1846	Transcriptional regulator
H7F27_13550	COG3852	Histidine kinase
H7F27_13565	COG3339	Conserved Protein
H7F27_13570	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H7F27_13575	COG0235	Class ii aldolase
H7F27_13580	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
H7F27_13585	COG1850	ribulose-bisphosphate carboxylase activity
H7F27_13590	COG0436	Aminotransferase
H7F27_13595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F27_13600	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
H7F27_13605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
H7F27_13615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7F27_13620	COG5002	protein histidine kinase activity
H7F27_13625	COG3594	Acyltransferase
H7F27_13640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7F27_13645	COG0501	Belongs to the peptidase M48B family
H7F27_13665	COG1191	sigma factor activity
H7F27_13670	COG0861	Integral membrane protein TerC family
H7F27_13675	COG0586	Pfam SNARE associated Golgi protein
H7F27_13680	COG5001	Diguanylate cyclase
H7F27_13680	COG3300	MHYT domain
H7F27_13685	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
H7F27_13690	COG1793	dna ligase
H7F27_13690	COG3285	dna ligase
H7F27_13705	COG1408	metallophosphoesterase
H7F27_13710	COG0726	polysaccharide deacetylase
H7F27_13715	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H7F27_13720	COG1846	Transcriptional regulator
H7F27_13735	COG0789	Transcriptional regulator
H7F27_13740	COG2239	Acts as a magnesium transporter
H7F27_13750	COG3212	peptidase
H7F27_13755	COG3212	peptidase
H7F27_13760	COG5002	protein histidine kinase activity
H7F27_13760	COG3850	Histidine kinase
H7F27_13765	COG0745	RESPONSE REGULATOR receiver
H7F27_13775	COG4721	ABC-type cobalt transport system, permease component
H7F27_13780	COG1122	ATPase activity
H7F27_13785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F27_13790	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_13795	COG1404	Belongs to the peptidase S8 family
H7F27_13800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H7F27_13805	COG0406	alpha-ribazole phosphatase activity
H7F27_13810	COG0590	tRNA wobble adenosine to inosine editing
H7F27_13815	COG0457	Tetratricopeptide repeat
H7F27_13815	COG0463	Glycosyl transferase, family 2
H7F27_13820	COG1764	response to oxidative stress
H7F27_13825	COG1846	Transcriptional regulator
H7F27_13830	COG1764	response to oxidative stress
H7F27_13835	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H7F27_13840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H7F27_13845	COG0788	formyltetrahydrofolate deformylase activity
H7F27_13850	COG2076	Multidrug Resistance protein
H7F27_13855	COG2076	Multidrug Resistance protein
H7F27_13860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F27_13865	COG2318	DinB family
H7F27_13870	COG2323	membrane
H7F27_13880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7F27_13880	COG1017	nitric oxide dioxygenase activity
H7F27_13885	COG1607	acyl-coa hydrolase
H7F27_13890	COG1834	amidinotransferase
H7F27_13895	COG2706	6-phosphogluconolactonase activity
H7F27_13900	COG4608	Belongs to the ABC transporter superfamily
H7F27_13905	COG0791	NLP P60 protein
H7F27_13910	COG4948	Mandelate Racemase Muconate Lactonizing
H7F27_13915	COG1619	proteins homologs of microcin C7 resistance protein MccF
H7F27_13920	COG4166	transmembrane transport
H7F27_13925	COG0444	Belongs to the ABC transporter superfamily
H7F27_13930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F27_13935	COG0601	transmembrane transport
H7F27_13940	COG2362	D-Aminopeptidase
H7F27_13945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H7F27_13950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7F27_13960	COG0463	Glycosyl transferase, family 2
H7F27_13965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H7F27_13970	COG0346	lactoylglutathione lyase activity
H7F27_13975	COG0531	amino acid
H7F27_13980	COG1392	Phosphate transport regulator
H7F27_13985	COG0306	phosphate transporter
H7F27_14045	COG3778	Protein conserved in bacteria
H7F27_14050	COG3299	homolog of phage Mu protein gp47
H7F27_14055	COG3628	GPW Gp25 family protein
H7F27_14065	COG4193	domain, Protein
H7F27_14070	COG1652	LysM domain
H7F27_14075	COG3953	SLT domain
H7F27_14075	COG5412	phage tail tape measure protein
H7F27_14125	COG4653	Phage capsid family
H7F27_14130	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H7F27_14135	COG5518	Phage portal protein
H7F27_14140	COG1783	phage Terminase large subunit
H7F27_14145	COG3728	DNA packaging
H7F27_14145	COG5484	DNA packaging
H7F27_14150	COG1595	DNA-templated transcription, initiation
H7F27_14170	COG1484	DNA-dependent DNA replication
H7F27_14175	COG1522	sequence-specific DNA binding
H7F27_14185	COG1396	sequence-specific DNA binding
H7F27_14190	COG2856	Zn peptidase
H7F27_14195	COG3546	catalase activity
H7F27_14200	COG4195	phage-related replication protein
H7F27_14210	COG3409	Peptidoglycan-binding domain 1 protein
H7F27_14210	COG1388	LysM domain
H7F27_14210	COG5632	N-Acetylmuramoyl-L-alanine amidase
H7F27_14215	COG2350	Protein conserved in bacteria
H7F27_14225	COG0457	Tetratricopeptide repeat
H7F27_14230	COG2318	DinB family
H7F27_14235	COG0730	response to heat
H7F27_14240	COG2721	sulfolactate sulfo-lyase activity
H7F27_14245	COG0246	Mannitol dehydrogenase
H7F27_14250	COG1609	Transcriptional regulator
H7F27_14255	COG2271	Major facilitator Superfamily
H7F27_14260	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_14265	COG1312	Catalyzes the dehydration of D-mannonate
H7F27_14270	COG1063	alcohol dehydrogenase
H7F27_14275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
H7F27_14280	COG2211	Major facilitator Superfamily
H7F27_14285	COG1904	glucuronate isomerase
H7F27_14290	COG1252	NADH dehydrogenase
H7F27_14300	COG4297	protein containing double-stranded beta helix domain
H7F27_14305	COG0697	spore germination
H7F27_14310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7F27_14315	COG0390	transport system, permease component
H7F27_14320	COG1587	Uroporphyrinogen-III synthase
H7F27_14335	COG1819	glycosyl
H7F27_14340	COG2124	cytochrome p450
H7F27_14350	COG1051	belongs to the nudix hydrolase family
H7F27_14360	COG2427	Protein of unknown function (DUF1641)
H7F27_14365	COG3383	formate dehydrogenase (NAD+) activity
H7F27_14375	COG2205	protein histidine kinase activity
H7F27_14380	COG5504	Zn-dependent protease
H7F27_14395	COG0726	polysaccharide deacetylase
H7F27_14405	COG0109	protoheme IX farnesyltransferase activity
H7F27_14425	COG0789	Transcriptional regulator
H7F27_14435	COG0697	spore germination
H7F27_14440	COG0583	DNA-binding transcription factor activity
H7F27_14445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F27_14465	COG3409	Peptidoglycan-binding domain 1 protein
H7F27_14495	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F27_14510	COG5505	Protein of unknown function (DUF819)
H7F27_14515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F27_14520	COG0626	cystathionine gamma-synthase activity
H7F27_14525	COG0626	cystathionine gamma-synthase activity
H7F27_14530	COG2382	esterase
H7F27_14535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
H7F27_14540	COG2153	protein acetylation
H7F27_14550	COG0210	DNA helicase
H7F27_14605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H7F27_14610	COG0351	phosphomethylpyrimidine kinase
H7F27_14615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H7F27_14620	COG2022	thiamine diphosphate biosynthetic process
H7F27_14625	COG2104	thiamine diphosphate biosynthetic process
H7F27_14630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F27_14635	COG0352	thiamine-phosphate diphosphorylase activity
H7F27_14640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7F27_14645	COG0569	domain protein
H7F27_14645	COG0475	glutathione-regulated potassium exporter activity
H7F27_14650	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7F27_14655	COG0564	pseudouridine synthase activity
H7F27_14660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7F27_14665	COG2357	RelA SpoT domain protein
H7F27_14675	COG4116	CYTH
H7F27_14680	COG0741	lytic transglycosylase activity
H7F27_14685	COG2346	COG2346, Truncated hemoglobins
H7F27_14690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7F27_14700	COG1164	Oligoendopeptidase f
H7F27_14705	COG4469	Competence protein
H7F27_14710	COG4862	establishment of competence for transformation
H7F27_14720	COG0861	Integral membrane protein TerC family
H7F27_14725	COG1393	Belongs to the ArsC family
H7F27_14730	COG0456	acetyltransferase
H7F27_14735	COG2814	Major facilitator Superfamily
H7F27_14740	COG4608	Belongs to the ABC transporter superfamily
H7F27_14745	COG0444	Belongs to the ABC transporter superfamily
H7F27_14750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F27_14755	COG0601	transmembrane transport
H7F27_14760	COG4166	transmembrane transport
H7F27_14765	COG0180	Tryptophanyl-tRNA synthetase
H7F27_14775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7F27_14780	COG0601	transmembrane transport
H7F27_14790	COG4608	Belongs to the ABC transporter superfamily
H7F27_14795	COG0444	Belongs to the ABC transporter superfamily
H7F27_14800	COG5504	Zn-dependent protease
H7F27_14805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7F27_14810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F27_14825	COG1744	ABC transporter substrate-binding protein PnrA-like
H7F27_14835	COG2267	carboxylic ester hydrolase activity
H7F27_14850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H7F27_14855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H7F27_14860	COG0505	Belongs to the CarA family
H7F27_14865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7F27_14875	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7F27_14880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H7F27_14885	COG2271	Major facilitator Superfamily
H7F27_14890	COG0277	FAD linked oxidase domain protein
H7F27_14900	COG2151	metal-sulfur cluster biosynthetic enzyme
H7F27_14905	COG1073	alpha beta
H7F27_14910	COG0561	phosphatase activity
H7F27_14930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F27_14935	COG1307	EDD domain protein, DegV family
H7F27_14940	COG3227	Zinc metalloprotease (Elastase)
H7F27_14955	COG1695	Transcriptional regulator
H7F27_14975	COG2996	Protein conserved in bacteria
H7F27_14980	COG1666	GTP binding
H7F27_14985	COG0646	methionine synthase
H7F27_14985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7F27_14990	COG2153	protein acetylation
H7F27_14995	COG0454	-acetyltransferase
H7F27_15000	COG2814	Major facilitator Superfamily
H7F27_15005	COG4948	Mandelate Racemase Muconate Lactonizing
H7F27_15010	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F27_15015	COG1809	phosphosulfolactate synthase activity
H7F27_15020	COG2045	Belongs to the ComB family
H7F27_15025	COG0175	sulfate reduction
H7F27_15030	COG2046	Belongs to the sulfate adenylyltransferase family
H7F27_15035	COG0529	Catalyzes the synthesis of activated sulfate
H7F27_15040	COG2267	carboxylic ester hydrolase activity
H7F27_15045	COG1357	PFAM Pentapeptide repeats (8 copies)
H7F27_15050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F27_15055	COG1279	arginine transmembrane transporter activity
H7F27_15060	COG2318	DinB family
H7F27_15065	COG0673	inositol 2-dehydrogenase activity
H7F27_15070	COG1609	Transcriptional regulator
H7F27_15075	COG1917	Cupin 2, conserved barrel domain protein
H7F27_15075	COG2207	Transcriptional regulator
H7F27_15080	COG0534	Mate efflux family protein
H7F27_15085	COG1562	ergosterol biosynthetic process
H7F27_15090	COG2318	DinB family
H7F27_15095	COG0367	asparagine synthase
H7F27_15105	COG1404	Belongs to the peptidase S8 family
H7F27_15115	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7F27_15120	COG5337	Spore coat protein CotH
H7F27_15160	COG1403	HNH endonuclease
H7F27_15165	COG0419	ATPase involved in DNA repair
H7F27_15170	COG0420	3'-5' exonuclease activity
H7F27_15175	COG1074	ATP-dependent DNA helicase activity
H7F27_15180	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
H7F27_15185	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
H7F27_15195	COG4533	DNA binding
H7F27_15200	COG2814	Major facilitator Superfamily
H7F27_15200	COG0477	Major facilitator Superfamily
H7F27_15205	COG3180	Ammonia monooxygenase
H7F27_15210	COG1609	Transcriptional regulator
H7F27_15215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H7F27_15220	COG0561	phosphatase activity
H7F27_15225	COG0673	inositol 2-dehydrogenase activity
H7F27_15230	COG0738	Major facilitator superfamily
H7F27_15235	COG1846	Transcriptional regulator
H7F27_15240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F27_15245	COG0681	Belongs to the peptidase S26 family
H7F27_15250	COG0398	Pfam SNARE associated Golgi protein
H7F27_15265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F27_15275	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_15280	COG4903	ComK protein
H7F27_15290	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_15295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F27_15295	COG0723	plastoquinol--plastocyanin reductase activity
H7F27_15300	COG0840	transmembrane signaling receptor activity
H7F27_15305	COG1268	BioY protein
H7F27_15310	COG0318	PFAM AMP-dependent synthetase and ligase
H7F27_15315	COG0183	Belongs to the thiolase family
H7F27_15320	COG0406	alpha-ribazole phosphatase activity
H7F27_15325	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H7F27_15330	COG0604	alcohol dehydrogenase
H7F27_15335	COG0456	acetyltransferase
H7F27_15340	COG1404	Belongs to the peptidase S8 family
H7F27_15345	COG0501	Belongs to the peptidase M48B family
H7F27_15355	COG0318	PFAM AMP-dependent synthetase and ligase
H7F27_15360	COG0702	epimerase
H7F27_15365	COG0095	Lipoate-protein ligase
H7F27_15370	COG1234	tRNA 3'-trailer cleavage
H7F27_15380	COG1301	dicarboxylic acid transport
H7F27_15385	COG4405	Protein conserved in bacteria
H7F27_15390	COG1363	Peptidase, m42
H7F27_15395	COG4377	Putative membrane peptidase family (DUF2324)
H7F27_15400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H7F27_15405	COG1511	domain protein
H7F27_15410	COG1309	transcriptional regulator
H7F27_15415	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H7F27_15420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H7F27_15425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H7F27_15430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7F27_15435	COG2329	Antibiotic biosynthesis monooxygenase
H7F27_15445	COG3069	C4-dicarboxylate transmembrane transporter activity
H7F27_15450	COG1473	amidohydrolase
H7F27_15460	COG4473	ABC transporter
H7F27_15465	COG1131	(ABC) transporter
H7F27_15470	COG0537	adenosine 5'-monophosphoramidase activity
H7F27_15475	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H7F27_15490	COG4980	gas vesicle protein
H7F27_15495	COG1846	Transcriptional regulator
H7F27_15525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F27_15535	COG3481	metal-dependent phosphohydrolase, HD sub domain
H7F27_15540	COG4717	serine-type aminopeptidase activity
H7F27_15545	COG0420	3'-5' exonuclease activity
H7F27_15550	COG1668	transmembrane transport
H7F27_15555	COG4152	abc transporter atp-binding protein
H7F27_15565	COG1024	Enoyl-CoA hydratase
H7F27_15575	COG0490	domain, Protein
H7F27_15580	COG0475	glutathione-regulated potassium exporter activity
H7F27_15585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7F27_15590	COG0561	phosphatase activity
H7F27_15595	COG4335	DNA alkylation repair
H7F27_15600	COG3679	Belongs to the UPF0342 family
H7F27_15605	COG4399	Belongs to the UPF0754 family
H7F27_15610	COG0189	ligase activity
H7F27_15615	COG0189	ligase activity
H7F27_15635	COG0702	epimerase
H7F27_15640	COG1132	(ABC) transporter
H7F27_15645	COG1132	(ABC) transporter
H7F27_15650	COG0589	response to stress
H7F27_15655	COG1757	Na H antiporter
H7F27_15660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F27_15665	COG0726	polysaccharide deacetylase
H7F27_15670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7F27_15675	COG0668	transmembrane transport
H7F27_15685	COG0584	glycerophosphoryl diester phosphodiesterase
H7F27_15690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F27_15695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H7F27_15700	COG1253	flavin adenine dinucleotide binding
H7F27_15705	COG0436	Aminotransferase
H7F27_15710	COG0789	Transcriptional regulator
H7F27_15715	COG1253	flavin adenine dinucleotide binding
H7F27_15720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F27_15725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7F27_15730	COG0204	Acyl-transferase
H7F27_15735	COG0667	Aldo Keto reductase
H7F27_15740	COG1595	DNA-templated transcription, initiation
H7F27_15755	COG0456	acetyltransferase
H7F27_15765	COG0733	neurotransmitter:sodium symporter activity
H7F27_15770	COG0531	amino acid
H7F27_15775	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_15780	COG0372	Belongs to the citrate synthase family
H7F27_15785	COG0583	DNA-binding transcription factor activity
H7F27_15790	COG1388	LysM domain
H7F27_15790	COG0791	NLP P60 protein
H7F27_15795	COG1785	Belongs to the alkaline phosphatase family
H7F27_15800	COG2719	SpoVR family
H7F27_15805	COG0668	transmembrane transport
H7F27_15810	COG1959	2 iron, 2 sulfur cluster binding
H7F27_15815	COG1388	LysM domain
H7F27_15815	COG0791	NLP P60 protein
H7F27_15830	COG0431	NADPH-dependent FMN reductase
H7F27_15835	COG2197	response regulator
H7F27_15840	COG2203	Gaf domain
H7F27_15840	COG4585	Histidine kinase
H7F27_15845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F27_15850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H7F27_15855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7F27_15860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H7F27_15865	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
H7F27_15870	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H7F27_15880	COG3153	acetyltransferase
H7F27_15880	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7F27_15885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7F27_15890	COG0517	IMP dehydrogenase activity
H7F27_15900	COG0564	pseudouridine synthase activity
H7F27_15905	COG3764	Sortase (surface protein transpeptidase)
H7F27_15910	COG4085	toxin activity
H7F27_15910	COG1525	nuclease
H7F27_15910	COG0737	Belongs to the 5'-nucleotidase family
H7F27_15915	COG5577	PFAM Coat F domain
H7F27_15935	COG1823	symporter activity
H7F27_15940	COG3706	GGDEF domain
H7F27_15945	COG1464	Belongs to the NlpA lipoprotein family
H7F27_15950	COG1278	Cold shock
H7F27_15955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F27_15960	COG1131	(ABC) transporter
H7F27_15965	COG1131	(ABC) transporter
H7F27_15970	COG1725	Transcriptional regulator
H7F27_15985	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7F27_15990	COG2814	Major facilitator Superfamily
H7F27_15995	COG1566	PFAM secretion protein HlyD family protein
H7F27_16000	COG1846	Transcriptional regulator
H7F27_16005	COG2718	Belongs to the UPF0229 family
H7F27_16010	COG2766	serine protein kinase
H7F27_16015	COG1664	Polymer-forming cytoskeletal
H7F27_16020	COG1664	Polymer-forming cytoskeletal
H7F27_16025	COG0789	Transcriptional regulator
H7F27_16030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7F27_16040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7F27_16045	COG3382	B3 4 domain protein
H7F27_16055	COG1476	TRANSCRIPTIONal
H7F27_16065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H7F27_16075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F27_16080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7F27_16085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7F27_16090	COG1116	anion transmembrane transporter activity
H7F27_16095	COG0753	catalase activity
H7F27_16105	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H7F27_16110	COG3340	Belongs to the peptidase S51 family
H7F27_16120	COG5577	PFAM Coat F domain
H7F27_16125	COG1063	alcohol dehydrogenase
H7F27_16135	COG4326	sporulation control protein
H7F27_16245	COG0735	belongs to the Fur family
H7F27_16250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7F27_16255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H7F27_16260	COG4129	membrane
H7F27_16265	COG1132	(ABC) transporter
H7F27_16270	COG3557	Belongs to the UPF0374 family
H7F27_16285	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_16295	COG1194	a g-specific adenine glycosylase
H7F27_16305	COG4485	Bacterial membrane protein, YfhO
H7F27_16310	COG0463	Glycosyl transferase, family 2
H7F27_16315	COG0596	Alpha beta hydrolase
H7F27_16320	COG5658	integral membrane protein
H7F27_16325	COG3103	Sh3 type 3 domain protein
H7F27_16330	COG1476	TRANSCRIPTIONal
H7F27_16345	COG2814	Major facilitator Superfamily
H7F27_16355	COG2137	regulation of response to DNA damage stimulus
H7F27_16360	COG1090	epimerase
H7F27_16375	COG0778	Nitroreductase
H7F27_16380	COG0384	phenazine biosynthesis protein PhzF
H7F27_16385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_16390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_16395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F27_16400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H7F27_16400	COG0392	lysyltransferase activity
H7F27_16405	COG1846	Transcriptional regulator
H7F27_16410	COG2814	Major facilitator Superfamily
H7F27_16420	COG2814	Major facilitator Superfamily
H7F27_16425	COG1309	transcriptional regulator
H7F27_16430	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
H7F27_16435	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F27_16440	COG1695	Transcriptional regulator
H7F27_16445	COG0842	Transport permease protein
H7F27_16450	COG1511	domain protein
H7F27_16450	COG0842	Transport permease protein
H7F27_16455	COG1131	(ABC) transporter
H7F27_16460	COG2197	response regulator
H7F27_16465	COG4585	Histidine kinase
H7F27_16470	COG0673	inositol 2-dehydrogenase activity
H7F27_16475	COG1082	Xylose isomerase domain protein TIM barrel
H7F27_16480	COG2814	Major facilitator Superfamily
H7F27_16485	COG4977	sequence-specific DNA binding
H7F27_16485	COG1917	Cupin 2, conserved barrel domain protein
H7F27_16490	COG2514	catechol 2,3-dioxygenase activity
H7F27_16495	COG2259	Doxx family
H7F27_16500	COG1132	(ABC) transporter
H7F27_16505	COG1132	(ABC) transporter
H7F27_16510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_16510	COG1263	PTS System
H7F27_16515	COG1737	Transcriptional regulator
H7F27_16520	COG1486	melibiose metabolic process
H7F27_16525	COG4842	Belongs to the WXG100 family
H7F27_16550	COG1742	UPF0060 membrane protein
H7F27_16560	COG3284	Transcriptional regulator
H7F27_16570	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7F27_16575	COG0022	dehydrogenase e1 component
H7F27_16580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7F27_16590	COG4637	Psort location Cytoplasmic, score
H7F27_16605	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H7F27_16615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F27_16620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F27_16625	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H7F27_16630	COG0598	Magnesium transport protein CorA
H7F27_16635	COG2084	Dehydrogenase
H7F27_16640	COG0726	polysaccharide deacetylase
H7F27_16650	COG0535	radical SAM domain protein
H7F27_16655	COG0668	transmembrane transport
H7F27_16665	COG0387	Pfam Sodium calcium exchanger
H7F27_16670	COG0477	Major facilitator Superfamily
H7F27_16675	COG1295	ribonuclease BN
H7F27_16680	COG4980	gas vesicle protein
H7F27_16685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7F27_16690	COG4840	Belongs to the UPF0435 family
H7F27_16695	COG2814	Major facilitator Superfamily
H7F27_16700	COG0693	protein deglycase activity
H7F27_16705	COG0737	Belongs to the 5'-nucleotidase family
H7F27_16715	COG0778	Nitroreductase
H7F27_16720	COG2188	Transcriptional regulator
H7F27_16725	COG0366	Alpha amylase catalytic
H7F27_16730	COG1263	PTS System
H7F27_16730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_16745	COG1368	sulfuric ester hydrolase activity
H7F27_16750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_16750	COG1263	PTS System
H7F27_16755	COG0024	Methionine aminopeptidase
H7F27_16775	COG2258	MOSC domain
H7F27_16780	COG1254	Belongs to the acylphosphatase family
H7F27_16785	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
H7F27_16790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7F27_16795	COG2851	Citrate transporter
H7F27_16800	COG3181	Tripartite tricarboxylate transporter family receptor
H7F27_16805	COG4565	transcriptional regulatory protein
H7F27_16810	COG3290	protein histidine kinase activity
H7F27_16820	COG0463	Glycosyl transferase, family 2
H7F27_16840	COG0471	metal ion transport
H7F27_16845	COG3866	Pectate lyase
H7F27_16860	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H7F27_16865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_16870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_16875	COG1120	ATPase activity
H7F27_16880	COG2130	NADP-dependent
H7F27_16885	COG0456	acetyltransferase
H7F27_16890	COG0513	Belongs to the DEAD box helicase family
H7F27_16895	COG0488	(ABC) transporter
H7F27_16905	COG2814	Major facilitator Superfamily
H7F27_16910	COG0789	Transcriptional regulator
H7F27_16920	COG0488	(ABC) transporter
H7F27_16925	COG0840	transmembrane signaling receptor activity
H7F27_16930	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_16935	COG0531	amino acid
H7F27_16940	COG1011	Hydrolase
H7F27_16945	COG2223	nitrite transmembrane transporter activity
H7F27_16950	COG1442	glycosyl transferase family 8
H7F27_16955	COG1216	Glycosyl transferase, family 2
H7F27_16960	COG1442	glycosyl transferase family 8
H7F27_16965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7F27_16970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7F27_16975	COG1368	sulfuric ester hydrolase activity
H7F27_16980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7F27_16980	COG2124	cytochrome p450
H7F27_16995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7F27_17000	COG1846	Transcriptional regulator
H7F27_17005	COG0670	Belongs to the BI1 family
H7F27_17010	COG5583	Uncharacterized small protein (DUF2292)
H7F27_17015	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_17025	COG0346	lactoylglutathione lyase activity
H7F27_17030	COG2329	Antibiotic biosynthesis monooxygenase
H7F27_17035	COG2323	membrane
H7F27_17040	COG1486	melibiose metabolic process
H7F27_17045	COG0395	ABC-type sugar transport system, permease component
H7F27_17050	COG4209	transmembrane transport
H7F27_17055	COG1653	transport
H7F27_17065	COG1874	Beta-galactosidase
H7F27_17070	COG2755	lipolytic protein G-D-S-L family
H7F27_17075	COG0667	Aldo Keto reductase
H7F27_17080	COG3401	FG-GAP repeat protein
H7F27_17085	COG3401	FG-GAP repeat protein
H7F27_17090	COG5578	integral membrane protein
H7F27_17100	COG2755	lipolytic protein G-D-S-L family
H7F27_17105	COG2207	Transcriptional regulator
H7F27_17110	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
H7F27_17115	COG0395	ABC-type sugar transport system, permease component
H7F27_17120	COG1175	transmembrane transport
H7F27_17125	COG1653	transport
H7F27_17130	COG4753	response regulator
H7F27_17130	COG2207	Transcriptional regulator
H7F27_17135	COG2972	Histidine kinase
H7F27_17140	COG5578	integral membrane protein
H7F27_17150	COG0454	-acetyltransferase
H7F27_17155	COG3546	catalase activity
H7F27_17170	COG1309	transcriptional regulator
H7F27_17175	COG2159	amidohydrolase
H7F27_17180	COG0702	epimerase
H7F27_17185	COG3631	Ketosteroid isomerase-related protein
H7F27_17190	COG1309	transcriptional regulator
H7F27_17200	COG0217	transcriptional regulatory protein
H7F27_17210	COG0457	Tetratricopeptide repeat
H7F27_17215	COG3391	amine dehydrogenase activity
H7F27_17220	COG3586	endonuclease activity
H7F27_17230	COG5444	nuclease activity
H7F27_17290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H7F27_17295	COG1597	lipid kinase activity
H7F27_17300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7F27_17305	COG1309	transcriptional regulator
H7F27_17310	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F27_17315	COG0154	amidase activity
H7F27_17320	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7F27_17325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F27_17330	COG1285	pathogenesis
H7F27_17335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7F27_17340	COG4851	CamS sex pheromone cAM373 precursor
H7F27_17345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H7F27_17350	COG0210	DNA helicase
H7F27_17355	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
H7F27_17360	COG0069	glutamate synthase activity
H7F27_17365	COG4496	protein, YerC YecD
H7F27_17370	COG1470	cell adhesion involved in biofilm formation
H7F27_17375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7F27_17385	COG0531	amino acid
H7F27_17395	COG0151	Belongs to the GarS family
H7F27_17400	COG0138	bifunctional purine biosynthesis protein purh
H7F27_17405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7F27_17410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H7F27_17415	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H7F27_17420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F27_17425	COG0047	phosphoribosylformylglycinamidine synthase activity
H7F27_17430	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7F27_17435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H7F27_17440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7F27_17445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7F27_17450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H7F27_17460	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
H7F27_17470	COG3064	Membrane
H7F27_17475	COG2252	PERMEase
H7F27_17495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7F27_17495	COG0519	Catalyzes the synthesis of GMP from XMP
H7F27_17500	COG1305	Transglutaminase-like
H7F27_17505	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
H7F27_17510	COG0714	Associated with various cellular activities
H7F27_17515	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F27_17520	COG1113	amino acid transport
H7F27_17525	COG2132	Multicopper oxidase
H7F27_17535	COG2267	carboxylic ester hydrolase activity
H7F27_17550	COG0823	Involved in the tonB-independent uptake of proteins
H7F27_17555	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7F27_17560	COG1063	alcohol dehydrogenase
H7F27_17565	COG2814	Major facilitator Superfamily
H7F27_17575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7F27_17580	COG2211	Major facilitator Superfamily
H7F27_17585	COG1063	alcohol dehydrogenase
H7F27_17590	COG0457	Tetratricopeptide repeat
H7F27_17600	COG3409	Peptidoglycan-binding domain 1 protein
H7F27_17615	COG1266	CAAX protease self-immunity
H7F27_17625	COG0805	protein transport
H7F27_17630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F27_17635	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
H7F27_17640	COG0315	cyclic pyranopterin monophosphate synthase activity
H7F27_17645	COG0488	(ABC) transporter
H7F27_17650	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H7F27_17655	COG0456	acetyltransferase
H7F27_17660	COG1214	PFAM Peptidase M22, glycoprotease
H7F27_17665	COG0802	atpase or kinase
H7F27_17670	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7F27_17715	COG4124	Belongs to the glycosyl hydrolase 26 family
H7F27_17720	COG1482	cell wall glycoprotein biosynthetic process
H7F27_17725	COG1940	carbohydrate kinase activity
H7F27_17730	COG2188	Transcriptional regulator
H7F27_17735	COG2723	6-phospho-beta-galactosidase activity
H7F27_17740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F27_17745	COG1447	Phosphotransferase system cellobiose-specific component IIA
H7F27_17750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H7F27_17755	COG2814	Major facilitator Superfamily
H7F27_17760	COG1388	LysM domain
H7F27_17765	COG1078	dGTPase activity
H7F27_17780	COG1785	Belongs to the alkaline phosphatase family
H7F27_17795	COG1819	glycosyl
H7F27_17800	COG1388	LysM domain
H7F27_17800	COG3858	chitin binding
H7F27_17805	COG1802	Transcriptional regulator
H7F27_17810	COG0730	response to heat
H7F27_17815	COG2814	Major facilitator Superfamily
H7F27_17825	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7F27_17830	COG1396	sequence-specific DNA binding
H7F27_17835	COG1846	Transcriptional regulator
H7F27_17840	COG0778	Nitroreductase
H7F27_17845	COG2409	Drug exporters of the RND superfamily
H7F27_17845	COG1033	growth of symbiont in host cell
H7F27_17850	COG1846	Transcriptional regulator
H7F27_17855	COG2318	DinB family
H7F27_17860	COG1113	amino acid transport
H7F27_17865	COG0488	(ABC) transporter
H7F27_17870	COG1082	Xylose isomerase domain protein TIM barrel
H7F27_17875	COG2814	Major facilitator Superfamily
H7F27_17880	COG1609	Transcriptional regulator
H7F27_17885	COG0673	inositol 2-dehydrogenase activity
H7F27_17895	COG0456	acetyltransferase
H7F27_17905	COG1309	transcriptional regulator
H7F27_17910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_17915	COG2323	membrane
H7F27_17920	COG1522	sequence-specific DNA binding
H7F27_17925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
H7F27_17930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F27_17935	COG0596	Alpha beta hydrolase
H7F27_17940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F27_17945	COG0697	spore germination
H7F27_17950	COG2030	dehydratase
H7F27_17955	COG1482	cell wall glycoprotein biosynthetic process
H7F27_17960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_17960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F27_17960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7F27_17965	COG3711	transcriptional antiterminator
H7F27_17965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7F27_17970	COG0456	acetyltransferase
H7F27_17980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H7F27_17985	COG1733	regulation of RNA biosynthetic process
H7F27_17990	COG3545	Serine hydrolase
H7F27_18000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F27_18005	COG0697	spore germination
H7F27_18020	COG0693	protein deglycase activity
H7F27_18035	COG2808	Putative FMN-binding domain
H7F27_18040	COG0456	acetyltransferase
H7F27_18045	COG1846	Transcriptional regulator
H7F27_18050	COG2364	Membrane
H7F27_18065	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
H7F27_18085	COG0346	lactoylglutathione lyase activity
H7F27_18090	COG2315	Protein conserved in bacteria
H7F27_18095	COG1329	Transcriptional regulator
H7F27_18105	COG1278	Cold shock
H7F27_18110	COG1278	Cold shock
H7F27_18115	COG3239	Fatty acid desaturase
H7F27_18120	COG1476	TRANSCRIPTIONal
H7F27_18145	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7F27_18175	COG2856	Zn peptidase
H7F27_18210	COG1191	sigma factor activity
H7F27_18275	COG3091	SprT-like family
H7F27_18285	COG2183	response to ionizing radiation
H7F27_18290	COG1846	Transcriptional regulator
H7F27_18295	COG1673	EVE domain
H7F27_18305	COG2208	phosphoserine phosphatase activity
H7F27_18310	COG1191	sigma factor activity
H7F27_18315	COG2172	sigma factor antagonist activity
H7F27_18320	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_18325	COG2208	phosphoserine phosphatase activity
H7F27_18330	COG2172	sigma factor antagonist activity
H7F27_18335	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_18340	COG1366	Belongs to the anti-sigma-factor antagonist family
H7F27_18345	COG2337	Toxic component of a toxin-antitoxin (TA) module
H7F27_18350	COG0864	Transcriptional regulator
H7F27_18355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7F27_18360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7F27_18365	COG0736	holo-[acyl-carrier-protein] synthase activity
H7F27_18370	COG0705	Rhomboid family
H7F27_18375	COG3428	Bacterial PH domain
H7F27_18380	COG3402	PFAM membrane-flanked domain
H7F27_18385	COG0513	Belongs to the DEAD box helicase family
H7F27_18390	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7F27_18395	COG1181	Belongs to the D-alanine--D-alanine ligase family
H7F27_18400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H7F27_18405	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H7F27_18420	COG1960	acyl-CoA dehydrogenase activity
H7F27_18430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H7F27_18435	COG1131	(ABC) transporter
H7F27_18440	COG1301	dicarboxylic acid transport
H7F27_18445	COG0628	permease
H7F27_18450	COG1301	dicarboxylic acid transport
H7F27_18455	COG4565	transcriptional regulatory protein
H7F27_18460	COG3290	protein histidine kinase activity
H7F27_18465	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H7F27_18470	COG3546	catalase activity
H7F27_18480	COG2329	Antibiotic biosynthesis monooxygenase
H7F27_18485	COG0662	Cupin 2, conserved barrel domain protein
H7F27_18490	COG3729	General stress protein
H7F27_18495	COG2217	Heavy metal translocating P-type atpase
H7F27_18500	COG4876	unkown
H7F27_18505	COG2261	transglycosylase associated protein
H7F27_18510	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F27_18520	COG0028	Belongs to the TPP enzyme family
H7F27_18525	COG0494	nUDIX hydrolase
H7F27_18530	COG0531	amino acid
H7F27_18540	COG1215	transferase activity, transferring glycosyl groups
H7F27_18545	COG5298	Protein conserved in bacteria
H7F27_18550	COG3706	GGDEF domain
H7F27_18555	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H7F27_18560	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H7F27_18560	COG0551	DNA topoisomerase type I activity
H7F27_18565	COG1522	sequence-specific DNA binding
H7F27_18570	COG2814	Major facilitator Superfamily
H7F27_18575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7F27_18585	COG3871	stress protein (general stress protein 26)
H7F27_18590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F27_18595	COG1917	Cupin 2, conserved barrel domain protein
H7F27_18600	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_18605	COG2226	methyltransferase
H7F27_18610	COG0318	PFAM AMP-dependent synthetase and ligase
H7F27_18615	COG3711	transcriptional antiterminator
H7F27_18620	COG4989	oxidoreductase activity
H7F27_18625	COG0768	penicillin binding
H7F27_18630	COG2329	Antibiotic biosynthesis monooxygenase
H7F27_18640	COG2755	lipolytic protein G-D-S-L family
H7F27_18645	COG1414	Transcriptional regulator
H7F27_18650	COG1984	allophanate hydrolase subunit 2
H7F27_18655	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H7F27_18660	COG4336	lyase activity
H7F27_18665	COG1914	H( )-stimulated, divalent metal cation uptake system
H7F27_18670	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H7F27_18675	COG0561	phosphatase activity
H7F27_18685	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H7F27_18695	COG0473	3-isopropylmalate dehydrogenase activity
H7F27_18700	COG0246	Mannitol dehydrogenase
H7F27_18715	COG1349	DNA-binding transcription factor activity
H7F27_18720	COG2372	response to copper ion
H7F27_18720	COG1276	copper resistance
H7F27_18725	COG4549	nuclear export factor GLE1
H7F27_18730	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_18735	COG4975	Glucose uptake
H7F27_18740	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_18745	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7F27_18750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F27_18755	COG0640	Transcriptional regulator
H7F27_18760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7F27_18765	COG0778	Nitroreductase
H7F27_18770	COG1309	transcriptional regulator
H7F27_18775	COG2814	Major facilitator Superfamily
H7F27_18780	COG4607	ABC-type enterochelin transport system periplasmic component
H7F27_18785	COG4604	ABC transporter, ATP-binding protein
H7F27_18790	COG4605	iron ion homeostasis
H7F27_18795	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_18800	COG0527	aspartate kinase activity
H7F27_18820	COG0457	Tetratricopeptide repeat
H7F27_18825	COG3850	Histidine kinase
H7F27_18825	COG5002	protein histidine kinase activity
H7F27_18830	COG0745	RESPONSE REGULATOR receiver
H7F27_18835	COG0577	efflux transmembrane transporter activity
H7F27_18840	COG1136	(ABC) transporter
H7F27_18845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7F27_18855	COG0697	spore germination
H7F27_18865	COG5434	Belongs to the glycosyl hydrolase 28 family
H7F27_18870	COG3104	oligopeptide transport
H7F27_18875	COG0596	Alpha beta hydrolase
H7F27_18890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H7F27_18895	COG0163	prenyltransferase activity
H7F27_18900	COG0583	DNA-binding transcription factor activity
H7F27_18905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F27_18910	COG0765	amino acid transport
H7F27_18915	COG1126	abc transporter atp-binding protein
H7F27_18920	COG2364	Membrane
H7F27_18930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7F27_18935	COG0697	spore germination
H7F27_18945	COG2814	Major facilitator Superfamily
H7F27_18950	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7F27_18955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_18960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_18965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7F27_18970	COG1733	regulation of RNA biosynthetic process
H7F27_18975	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
H7F27_18980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H7F27_18985	COG0840	transmembrane signaling receptor activity
H7F27_18985	COG3290	protein histidine kinase activity
H7F27_18990	COG3209	COG3209 Rhs family protein
H7F27_19000	COG2723	6-phospho-beta-galactosidase activity
H7F27_19005	COG3842	ATPase activity
H7F27_19015	COG1714	RDD family
H7F27_19020	COG1063	alcohol dehydrogenase
H7F27_19025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7F27_19030	COG0765	amino acid transport
H7F27_19035	COG0523	cobalamin synthesis protein
H7F27_19045	COG1376	ErfK ybiS ycfS ynhG family protein
H7F27_19050	COG1469	GTP cyclohydrolase I activity
H7F27_19055	COG2223	nitrite transmembrane transporter activity
H7F27_19060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F27_19065	COG0243	molybdopterin cofactor binding
H7F27_19070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7F27_19075	COG2146	nitrite reductase [NAD(P)H] activity
H7F27_19080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7F27_19080	COG1587	Uroporphyrinogen-III synthase
H7F27_19085	COG0492	ferredoxin-NADP+ reductase activity
H7F27_19090	COG0701	Predicted permease
H7F27_19095	COG3689	TIGRFAM TIGR03943 family protein
H7F27_19100	COG2508	Transcriptional regulator
H7F27_19105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7F27_19110	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_19115	COG0506	proline dehydrogenase activity
H7F27_19120	COG3541	Predicted nucleotidyltransferase
H7F27_19125	COG3458	cephalosporin-C deacetylase activity
H7F27_19130	COG0583	DNA-binding transcription factor activity
H7F27_19135	COG2226	methyltransferase
H7F27_19145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H7F27_19155	COG1660	Displays ATPase and GTPase activities
H7F27_19160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7F27_19165	COG3665	Urea carboxylase-associated protein
H7F27_19170	COG1113	amino acid transport
H7F27_19175	COG3403	YqcI/YcgG family
H7F27_19180	COG1280	lysine exporter protein (LysE YggA)
H7F27_19185	COG1846	Transcriptional regulator
H7F27_19190	COG2814	Major facilitator Superfamily
H7F27_19195	COG1620	l-lactate permease
H7F27_19200	COG0039	L-malate dehydrogenase activity
H7F27_19205	COG0366	Alpha amylase catalytic
H7F27_19215	COG1288	antiporter activity
H7F27_19220	COG1473	amidohydrolase
H7F27_19225	COG2113	Glycine betaine
H7F27_19230	COG4176	ABC-type proline glycine betaine transport system permease component
H7F27_19235	COG4175	Glycine betaine
H7F27_19235	COG0517	IMP dehydrogenase activity
H7F27_19240	COG0640	Transcriptional regulator
H7F27_19245	COG2814	Major facilitator Superfamily
H7F27_19250	COG0477	Major facilitator Superfamily
H7F27_19255	COG3853	Toxic anion resistance protein (TelA)
H7F27_19270	COG1358	cellular component organization or biogenesis
H7F27_19285	COG0861	Integral membrane protein TerC family
H7F27_19290	COG2310	stress, protein
H7F27_19295	COG2310	stress, protein
H7F27_19300	COG2310	stress, protein
H7F27_19305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7F27_19310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7F27_19315	COG1121	(ABC) transporter
H7F27_19320	COG0803	Belongs to the bacterial solute-binding protein 9 family
H7F27_19325	COG0366	Alpha amylase catalytic
H7F27_19330	COG1028	Short-chain dehydrogenase reductase Sdr
H7F27_19335	COG0457	Tetratricopeptide repeat
H7F27_19340	COG1876	peptidase activity
H7F27_19345	COG1595	DNA-templated transcription, initiation
H7F27_19350	COG1595	DNA-templated transcription, initiation
H7F27_19360	COG0667	Aldo Keto reductase
H7F27_19365	COG1668	transmembrane transport
H7F27_19370	COG4555	ABC transporter
H7F27_19375	COG3279	Response regulator of the LytR AlgR family
H7F27_19380	COG3290	protein histidine kinase activity
H7F27_19385	COG3012	SEC-C Motif Domain Protein
H7F27_19385	COG1405	negative regulation of cell septum assembly
H7F27_19390	COG1714	RDD family
H7F27_19395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H7F27_19400	COG0252	asparaginase activity
H7F27_19405	COG1309	transcriptional regulator
H7F27_19410	COG0477	Major facilitator Superfamily
H7F27_19415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7F27_19420	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H7F27_19425	COG0805	protein transport
H7F27_19430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H7F27_19435	COG3540	Alkaline phosphatase
H7F27_19445	COG2304	oxidoreductase activity
H7F27_19450	COG3773	Cell wall hydrolase
H7F27_19470	COG1131	(ABC) transporter
H7F27_19475	COG2205	protein histidine kinase activity
H7F27_19480	COG0745	RESPONSE REGULATOR receiver
H7F27_19490	COG3173	Aminoglycoside phosphotransferase
H7F27_19495	COG2721	sulfolactate sulfo-lyase activity
H7F27_19500	COG2186	Transcriptional regulator
H7F27_19505	COG4948	Mandelate Racemase Muconate Lactonizing
H7F27_19510	COG2271	Major facilitator Superfamily
H7F27_19515	COG1012	belongs to the aldehyde dehydrogenase family
H7F27_19520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7F27_19525	COG0784	Response regulator, receiver
H7F27_19530	COG4191	Histidine kinase
H7F27_19535	COG2066	Belongs to the glutaminase family
H7F27_19540	COG1115	amino acid carrier protein
H7F27_19545	COG2040	homocysteine
H7F27_19550	COG0833	amino acid
H7F27_19555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F27_19565	COG2188	Transcriptional regulator
H7F27_19570	COG0363	glucosamine-6-phosphate deaminase activity
H7F27_19575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_19575	COG1263	PTS System
H7F27_19575	COG2190	(PTS) system
H7F27_19580	COG1301	dicarboxylic acid transport
H7F27_19585	COG1054	Belongs to the UPF0176 family
H7F27_19590	COG2207	Transcriptional regulator
H7F27_19595	COG2312	Erythromycin esterase
H7F27_19605	COG0688	phosphatidylethanolamine metabolic process
H7F27_19610	COG0586	Pfam SNARE associated Golgi protein
H7F27_19615	COG1183	phosphatidylcholine synthase activity
H7F27_19620	COG0596	Alpha beta hydrolase
H7F27_19630	COG3591	Belongs to the peptidase S1B family
H7F27_19635	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H7F27_19640	COG0371	Dehydrogenase
H7F27_19655	COG2271	Major facilitator Superfamily
H7F27_19660	COG1846	Transcriptional regulator
H7F27_19660	COG0456	acetyltransferase
H7F27_19670	COG2271	Major facilitator Superfamily
H7F27_19675	COG0584	glycerophosphoryl diester phosphodiesterase
H7F27_19680	COG0531	amino acid
H7F27_19690	COG2124	cytochrome p450
H7F27_19695	COG2602	Beta-lactamase
H7F27_19710	COG1113	amino acid transport
H7F27_19725	COG0515	serine threonine protein kinase
H7F27_19735	COG0642	Histidine kinase
H7F27_19740	COG0745	RESPONSE REGULATOR receiver
H7F27_19745	COG0596	Alpha beta hydrolase
H7F27_19755	COG1413	lyase activity
H7F27_19760	COG2814	Major facilitator Superfamily
H7F27_19765	COG0640	Transcriptional regulator
H7F27_19770	COG5609	conserved protein (DUF2294)
H7F27_19780	COG0288	reversible hydration of carbon dioxide
H7F27_19785	COG3002	Belongs to the UPF0753 family
H7F27_19790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7F27_19800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7F27_19805	COG4856	YbbR-like protein
H7F27_19810	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
H7F27_19815	COG5662	AntiSigma factor
H7F27_19820	COG1595	DNA-templated transcription, initiation
H7F27_19850	COG1683	Conserved Protein
H7F27_19855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7F27_19860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H7F27_19865	COG1737	Transcriptional regulator
H7F27_19870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H7F27_19870	COG1263	PTS System
H7F27_19875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7F27_19880	COG1472	Belongs to the glycosyl hydrolase 3 family
H7F27_19885	COG3876	Protein conserved in bacteria
H7F27_19890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F27_19890	COG2207	Transcriptional regulator
H7F27_19895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H7F27_19900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_19905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7F27_19910	COG2819	hydrolase of the alpha beta superfamily
H7F27_19915	COG0385	Bile acid
H7F27_19920	COG0659	secondary active sulfate transmembrane transporter activity
H7F27_20000	COG0726	polysaccharide deacetylase
H7F27_20005	COG2194	sulfuric ester hydrolase activity
H7F27_20015	COG0489	protein tyrosine kinase activity
H7F27_20020	COG0860	N-Acetylmuramoyl-L-alanine amidase
H7F27_20030	COG2226	methyltransferase
H7F27_20040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H7F27_20045	COG0101	tRNA pseudouridine synthase activity
H7F27_20050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
H7F27_20055	COG1122	ATPase activity
H7F27_20060	COG1122	ATPase activity
H7F27_20065	COG0203	ribosomal protein L17
H7F27_20070	COG0202	RNA polymerase activity
H7F27_20075	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H7F27_20085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H7F27_20095	COG0024	Methionine aminopeptidase
H7F27_20100	COG0563	adenylate kinase activity
H7F27_20105	COG0201	protein transport
H7F27_20110	COG0200	Binds to the 23S rRNA
H7F27_20125	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H7F27_20130	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H7F27_20135	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H7F27_20145	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H7F27_20155	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H7F27_20160	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H7F27_20170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H7F27_20190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H7F27_20205	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H7F27_20215	COG0596	Alpha beta hydrolase
H7F27_20220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H7F27_20225	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H7F27_20230	COG0049	tRNA binding
H7F27_20240	COG1358	cellular component organization or biogenesis
H7F27_20245	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H7F27_20250	COG0085	RNA polymerase activity
H7F27_20255	COG2813	Specifically methylates the guanine in position
H7F27_20270	COG0081	regulation of translation
H7F27_20280	COG0250	Participates in transcription elongation, termination and antitermination
H7F27_20285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H7F27_20295	COG1595	DNA-templated transcription, initiation
H7F27_20300	COG3688	RNA-binding protein containing a PIN domain
H7F27_20305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7F27_20310	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
H7F27_20315	COG0215	cysteine-tRNA ligase activity
H7F27_20320	COG1045	serine acetyltransferase
H7F27_20325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7F27_20330	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H7F27_20335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H7F27_20340	COG4956	integral membrane protein (PIN domain superfamily)
H7F27_20345	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
H7F27_20350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H7F27_20355	COG0542	response to heat
H7F27_20360	COG3869	Catalyzes the specific phosphorylation of arginine residues in
H7F27_20365	COG3880	PFAM UvrB UvrC protein
H7F27_20370	COG4463	regulation of RNA biosynthetic process
H7F27_20450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H7F27_20455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7F27_20460	COG1396	sequence-specific DNA binding
H7F27_20465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7F27_20470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7F27_20475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7F27_20480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7F27_20485	COG0512	Glutamine amidotransferase of anthranilate synthase
H7F27_20490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7F27_20495	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7F27_20500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7F27_20505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H7F27_20510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H7F27_20515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7F27_20520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H7F27_20525	COG0037	tRNA processing
H7F27_20530	COG0515	serine threonine protein kinase
H7F27_20535	COG2304	oxidoreductase activity
H7F27_20540	COG2208	phosphoserine phosphatase activity
H7F27_20555	COG1098	S1 RNA binding domain
H7F27_20560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7F27_20575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7F27_20580	COG3956	TIGRFAM MazG family protein
H7F27_20585	COG2244	polysaccharide biosynthetic process
H7F27_20590	COG2002	toxin-antitoxin pair type II binding
H7F27_20595	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7F27_20605	COG0193	aminoacyl-tRNA hydrolase activity
H7F27_20610	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H7F27_20615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7F27_20620	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H7F27_20625	COG2088	sporulation resulting in formation of a cellular spore
H7F27_20630	COG0251	oxidation-reduction process
H7F27_20635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H7F27_20640	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H7F27_20650	COG4466	Protein conserved in bacteria
H7F27_20660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7F27_20665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
H7F27_20670	COG3583	domain protein
H7F27_20670	COG3584	3D domain protein
H7F27_20675	COG0084	hydrolase, TatD family'
H7F27_20680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F27_20680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7F27_20685	COG2002	toxin-antitoxin pair type II binding
H7F27_20690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H7F27_20695	COG2827	Endonuclease containing a URI domain
H7F27_20700	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H7F27_20710	COG1774	PSP1 C-terminal conserved region
H7F27_20715	COG0470	DNA polymerase III